Adaptation and major chromosomal changes in populations of Saccharomyces cerevisiae
dc.contributor.author | Simlar, J. | en_US |
dc.contributor.author | Puskas-Rozsa, S. | en_US |
dc.contributor.author | Wilke, C. M. | en_US |
dc.contributor.author | Adams, Julian | en_US |
dc.date.accessioned | 2006-09-11T18:26:44Z | |
dc.date.available | 2006-09-11T18:26:44Z | |
dc.date.issued | 1992-07 | en_US |
dc.identifier.citation | Adams, Julian; Puskas-Rozsa, S.; Simlar, J.; Wilke, C. M.; (1992). "Adaptation and major chromosomal changes in populations of Saccharomyces cerevisiae ." Current Genetics 22(1): 13-19. <http://hdl.handle.net/2027.42/46975> | en_US |
dc.identifier.issn | 0172-8083 | en_US |
dc.identifier.issn | 1432-0983 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/46975 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1611666&dopt=citation | en_US |
dc.description.abstract | Thirteen independent populations of Saccharomyces cerevisiae (nine haploid and four diploid) were maintained in continuous culture for up to approximately 1000 generations, with growth limited by the concentration of organic phosphates in medium buffered at pH 6. Analysis of clones isolated from these populations showed that a number (17) of large-scale chromosomallength variants and rearrangements were present in the populations at their termination. Nine of the 16 yeast chromosomes were involved in such changes. Few of the changes could be explained by copy-number increases in the structural loci for acid phosphatase. Several considerations concerning the nature and frequency of the chromosome-length variants observed lead us to conclude that they are selectively advantageous. | en_US |
dc.format.extent | 1207340 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag | en_US |
dc.subject.other | Plant Sciences | en_US |
dc.subject.other | Adaptation | en_US |
dc.subject.other | Continuous Culture | en_US |
dc.subject.other | Proteomics | en_US |
dc.subject.other | Microbiology | en_US |
dc.subject.other | Life Sciences | en_US |
dc.subject.other | Chromosome Length Variants | en_US |
dc.subject.other | Biochemistry, General | en_US |
dc.subject.other | Cell Biology | en_US |
dc.subject.other | Microbial Genetics and Genomics | en_US |
dc.subject.other | Yeast | en_US |
dc.title | Adaptation and major chromosomal changes in populations of Saccharomyces cerevisiae | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Biology, University of Michigan, 48109, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Department of Biology, University of Michigan, 48109, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Department of Biology, University of Michigan, 48109, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Department of Biology, University of Michigan, 48109, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 1611666 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/46975/1/294_2004_Article_BF00351736.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF00351736 | en_US |
dc.identifier.source | Current Genetics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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