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An enzyme histochemical study of torpedoes and dendritic swellings in the cerebellum

dc.contributor.authorFriede, Reinhard L.en_US
dc.date.accessioned2006-09-11T18:44:02Z
dc.date.available2006-09-11T18:44:02Z
dc.date.issued1965-05en_US
dc.identifier.citationFriede, Reinhard L.; (1965). "An enzyme histochemical study of torpedoes and dendritic swellings in the cerebellum." Acta Neuropathologica 4(3): 288-292. <http://hdl.handle.net/2027.42/47226>en_US
dc.identifier.issn0001-6322en_US
dc.identifier.issn1432-0533en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/47226
dc.description.abstractIn 8 cases, the following enzymes were studied in the dendritic swellings and torpedoes of Purkinje cells of cerebellum: succinic dehydrogenase, cytochrome oxidase, lactic dehydrogenase, NAD-diaphorase, alkaline phosphatase, acid phosphatase, acetyl cholinesterase and nonspecific cholinesterase. Activity of the oxidative enzymes was always extremely high in the dendritic swellings, but varied greatly among cases in the torpedoes; 4 cases showed very weak activity of oxidative enzymes in torpedoes, while 4 other cases showed an intense reaction. Dendritic swellings and torpedoes exhibited no alkaline phosphatase, acetyl cholinesterase, or nonspecific cholinesterase activity. In Dendritenanschwellungen und Torpedos der Purkinje-Zellen des Kleinhirns von 8 Fällen wurden die folgenden Enzyme untersucht: Bernsteinsäure-Dehydrogenase, Cytochrom-Oxidase, Milchsäure-Dehydrogenase, NAD-Diaphorase, alkalische Phosphatase, saure Phosphatase, Acetylcholinesterase und unspezifische Cholinesterase. Die Aktivität der oxidativen Enzyme war in den Dendritenanschwellungen immer sehr hoch, in den Torpedos aber von Fall zu Fall sehr unterschiedlich: 4 Fälle zeigten nur sehr geringe Aktivität, die 4 anderen jedoch eine sehr intensive Reaktion. Die Dendritenanschwellungen und Torpedos zeigten keine Aktivität der alkalischen Phosphatase, Acetylcholinesterase oder unspezifischen Cholinesterase.en_US
dc.format.extent1388673 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherSpringer-Verlagen_US
dc.subject.otherPathologyen_US
dc.subject.otherMedicine & Public Healthen_US
dc.titleAn enzyme histochemical study of torpedoes and dendritic swellings in the cerebellumen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPathologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumMental Health Research Institute and Department of Pathology, The University of Michigan, Ann Arbor, Michiganen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/47226/1/401_2004_Article_BF00687526.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF00687526en_US
dc.identifier.sourceActa Neuropathologicaen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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