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Identification and DNA sequence of tdcR , a positive regulatory gene of the tdc operon of Escherichia coli

dc.contributor.authorSchweizer, Herbert P.en_US
dc.contributor.authorDatta, Prasantaen_US
dc.date.accessioned2006-09-11T19:08:05Z
dc.date.available2006-09-11T19:08:05Z
dc.date.issued1989-09en_US
dc.identifier.citationSchweizer, Herbert P.; Datta, Prasanta; (1989). "Identification and DNA sequence of tdcR , a positive regulatory gene of the tdc operon of Escherichia coli ." MGG Molecular & General Genetics 218(3): 516-522. <http://hdl.handle.net/2027.42/47570>en_US
dc.identifier.issn0026-8925en_US
dc.identifier.issn1617-4623en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/47570
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2573820&dopt=citationen_US
dc.description.abstractEfficient in vivo expression of the biodegradative threonine dehydratase ( tdc ) operon of Escherichia coli is dependent on a regulatory gene, tdcR . The tdcR gene is located 198 base pairs upstream of the tdc operon and is transcribed divergently from this operon. The nucleotide sequence of tdcR and two unrelated reading frames has been determined. The deduced amino acid sequence of TdcR indicates that is is a polypeptide of M r 12000 with 99 amino acid residues and contains a potential helix-turnhelix DNA binding motif. Deletion analysis and minicell expression of the tdcR gene suggest that TdcR may serve as a trans -acting positive activator for the tdc operon.en_US
dc.format.extent760094 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherSpringer-Verlagen_US
dc.subject.otherCell Biologyen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherGene Regulationen_US
dc.subject.otherTdc Activatoren_US
dc.subject.otherMicrobial Genetics and Genomicsen_US
dc.subject.otherTdc Operonen_US
dc.subject.otherEscherichia Colien_US
dc.subject.otherLife Sciencesen_US
dc.titleIdentification and DNA sequence of tdcR , a positive regulatory gene of the tdc operon of Escherichia colien_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelGeneticsen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan, Medical School, 48109-0606, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan, Medical School, 48109-0606, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid2573820en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/47570/1/438_2004_Article_BF00332418.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF00332418en_US
dc.identifier.sourceMGG Molecular & General Geneticsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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