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Large granular lymphocyte leukemia (LGL) in a child with hyper IgM syndrome and autoimmune hemolytic anemia

dc.contributor.authorKitchen, Brenda J.en_US
dc.contributor.authorBoxer, Laurence A.en_US
dc.date.accessioned2007-12-04T18:36:40Z
dc.date.available2009-01-07T20:01:15Zen_US
dc.date.issued2008-01en_US
dc.identifier.citationKitchen, Brenda J.; Boxer, Laurence A. (2008). "Large granular lymphocyte leukemia (LGL) in a child with hyper IgM syndrome and autoimmune hemolytic anemia." Pediatric Blood & Cancer 50(1): 142-145. <http://hdl.handle.net/2027.42/57398>en_US
dc.identifier.issn1545-5009en_US
dc.identifier.issn1545-5017en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/57398
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=16767728&dopt=citationen_US
dc.description.abstractWe describe a female with a history of autosomal recessive hyper-IgM (HIGM) syndrome along with a history of autoimmune hemolytic anemia and intermittent lymphadenopathy. She subsequently developed neutropenia, lymphocyostosis and mild thrombocytopenia. Flow cytometry of the peripheral blood revealed the presence of a marked predominance of cytotoxic T lymphocytes, shown to be clonal, with concomitant natural killer (NK) antigen expression. She responded to weekly methotrexate therapy. Pediatr Blood Cancer 2008;50:142–145. © 2006 Wiley-Liss, Inc.en_US
dc.format.extent106489 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherLife and Medical Sciencesen_US
dc.subject.otherCancer Research, Oncology and Pathologyen_US
dc.titleLarge granular lymphocyte leukemia (LGL) in a child with hyper IgM syndrome and autoimmune hemolytic anemiaen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPediatricsen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDivision of Hematology/Oncology, Department of Pediatrics and Communicable Diseases, University of Michigan, Mott Children's Hospital, Ann Arbor, Michigan ; Women's Hospital Rm L2110, 1500 E. Medical Center Dr., Box 0238, Ann Arbor, MI 48109.en_US
dc.contributor.affiliationumDivision of Hematology/Oncology, Department of Pediatrics and Communicable Diseases, University of Michigan, Mott Children's Hospital, Ann Arbor, Michiganen_US
dc.identifier.pmid16767728en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/57398/1/20902_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/pbc.20902en_US
dc.identifier.sourcePediatric Blood & Canceren_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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