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| Title: | Sleep and circadian rhythms in mood |
| Authors: | Armitage, R |
| Keywords: | Sleep
Depression |
| Issue Date: | 2007 |
| Publisher: | Blackwell Munksgaard |
| Citation: | Acta Scandinavica, 2007, 115, 104-115. <http://hdl.handle.net/2027.42/60185> |
| Abstract: | Objective: Self-reported sleep disturbances are present in over 80% of
patients with depression. However, sleep electroencephalography
(EEG) findings, based on overnight polysomnography have not always
differentiated depressed patients from healthy individuals.
Method: The present paper will review the findings on sleep EEG
studies in depression highlighting how recent technological and
methodological advances have impacted on study outcomes.
Results: The majority of studies, including our own work, do indicate
that sleep homeostasis and sleep EEG rhythms are abnormal in
depression, but the sleep disturbances were strongly moderated by
gender and age. Melancholic features of depression correlated
significantly with low slow-wave activity in depressed men, but not in
depressed women. Women with depression showed low temporal
coherence of sleep EEG rhythms but the presence or absence of
melancholic features did not influence correlations.
Conclusion: Diagnostic classification schemas and clinical features of
depression may influence sleep EEG findings, but gender may be a
more important consideration. |
| Appears in Collections: | Psychiatry, Department of
Interdisciplinary and Peer-Reviewed
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| armitage.ACTA.2007.pdf | | 181Kb | Adobe PDF | View/Open |
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