Now showing items 1-4 of 4
An improved method for immobilizing IgG antibodies on protein A-agarose
(Elsevier, 1990-03-09)
This report describes a modification of a procedure developed by others for crosslinking IgG to protein A which itself is covalently linked to a gel support. Earlier immunoaffinity columns were described as having large ...
The oral gold compound auranofin triggers arachidonate release and cyclooxygenase metabolism in the alveolar macrophage
(Elsevier, 1988-12)
We examined the effect of in vitro incubation with the oral gold compound auranofin (AF) on arachidonic acid (AA) release and metabolism by rat alveolar macrophages (AMs). AF stimulated dose- and time-dependent release of ...
Reduced 5-lipoxygenase metabolism of arachidonic acid in macrophages rrom 1,25-dihydroxyvitamin D3-deficient rats
(Elsevier, 1994-11)
The peripheral blood monocyte (PBM) migrates into tissues and differentiates into mature tissue macrophages. Previous investigations from our laboratory have demonstrated that PBM have reduced 5-lipoxygenase (5-LO) metabolism ...
TLR9 activation is a key event for the maintenance of a mycobacterial antigen-elicited pulmonary granulomatous response
(WILEY-VCH Verlag, 2007-10)
Type 1 (Th1) granulomas can be studied in mice sensitized with mycobacterium antigens followed by challenge of agarose beads covalently coupled to purified protein derivative. TLR9 is known to play a role in the regulation ...