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Receipt of Cardiac Medications Upon Discharge Among Men and Women With Acute Coronary Syndrome and Nonobstructive Coronary Artery Disease

dc.contributor.authorRamanath, Vijay S.en_US
dc.contributor.authorArmstrong, David F.en_US
dc.contributor.authorGrzybowski, Maryen_US
dc.contributor.authorRahnama-Mohagdam, Sahanden_US
dc.contributor.authorTamhane, Umesh U.en_US
dc.contributor.authorGordon, Kellyen_US
dc.contributor.authorFroehlich, James B.en_US
dc.contributor.authorEagle, Kim A.en_US
dc.contributor.authorJackson, Elizabeth A.en_US
dc.date.accessioned2010-02-02T15:30:13Z
dc.date.available2011-03-01T16:26:43Zen_US
dc.date.issued2010-01en_US
dc.identifier.citationRamanath, Vijay S.; Armstrong, David F.; Grzybowski, Mary; Rahnama-Mohagdam, Sahand; Tamhane, Umesh U.; Gordon, Kelly; Froehlich, James B.; Eagle, Kim A.; Jackson, Elizabeth A. (2010). "Receipt of Cardiac Medications Upon Discharge Among Men and Women With Acute Coronary Syndrome and Nonobstructive Coronary Artery Disease." Clinical Cardiology 33(1): 36-41. <http://hdl.handle.net/2027.42/64902>en_US
dc.identifier.issn0160-9289en_US
dc.identifier.issn1932-8737en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/64902
dc.description.abstractBackground Management of acute coronary syndrome (ACS) patients with nonobstructive epicardial coronary artery disease (CAD) remains poorly understood. Hypothesis Acute coronary syndrome patients with nonobstructive CAD are less likely to receive effective cardiac medications upon discharge from the hospital. Methods We identified patients hospitalized with ACS that underwent coronary angiography and had a 6-month follow-up. Patients were grouped by CAD severity: nonobstructive CAD (<50% blockage in all vessels) or obstructive CAD (≥50% blockage in ≥ 1 vessels). Data were collected on demographics, medications at discharge, and adverse outcomes at 6 months, for all patients. Results Of the 2264 ACS patients included in the study: 123 patients had nonobstructive CAD and 2141 had obstructive CAD. Cardiac risk factors including hypertension and diabetes were common among patients with nonobstructive CAD. Men and women with nonobstructive CAD were less likely to receive cardiac medications compared to patients with obstructive CAD including aspirin (87.8% vs 95.0%, P = 0.001), Β-blockers (74.0% vs 89.2%, P < 0.001), or statins (69.1% vs 81.2%, P = 0.001). No gender-related differences in discharge medications were observed for patients with nonobstructive CAD. However, women with nonobstructive CAD had similar rates of cardiac-related rehospitalization as men with obstructive CAD (23.3% and 25.9%, respectively). Conclusions Patients with nonobstructive CAD are less likely to receive evidence-based medications compared to patients with obstructive CAD, despite the presence of CAD risk factors and occurrence of an ACS event. Further research is warranted to determine if receipt of effective cardiac medications among patients with nonobstructive CAD would reduce cardiac-related events. Copyright © 2010 Wiley Periodicals, Inc.en_US
dc.format.extent123021 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWiley Periodicals, Inc.en_US
dc.subject.otherMedicine and Healthcareen_US
dc.subject.otherCardiovascular Diseaseen_US
dc.titleReceipt of Cardiac Medications Upon Discharge Among Men and Women With Acute Coronary Syndrome and Nonobstructive Coronary Artery Diseaseen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelInternal Medicine and Specialitiesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michiganen_US
dc.contributor.affiliationumDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michiganen_US
dc.contributor.affiliationumDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michiganen_US
dc.contributor.affiliationumDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michiganen_US
dc.contributor.affiliationumDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michiganen_US
dc.contributor.affiliationumDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michiganen_US
dc.contributor.affiliationumDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michiganen_US
dc.contributor.affiliationumDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan ; Division of Cardiovascular Medicine University of Michigan Health System 24 Frank Lloyd Wright Drive Ann Arbor, Michigan 48106.en_US
dc.contributor.affiliationotherDepartment of Medicine, Section of Cardiology, Dartmouth-Hitchcock Medical Center, Dartmouth Medical School, Lebanon, New Hampshireen_US
dc.identifier.pmid20063300en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/64902/1/20701_ftp.pdf
dc.identifier.doi10.1002/clc.20701en_US
dc.identifier.sourceClinical Cardiologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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