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Lead exposure and periodontitis in US adults

dc.contributor.authorSaraiva, M. C. P.en_US
dc.contributor.authorTaichman, Russell S.en_US
dc.contributor.authorBraun, T.en_US
dc.contributor.authorNriagu, Jerome O.en_US
dc.contributor.authorEklund, Stephen A.en_US
dc.contributor.authorBurt, Brian A.en_US
dc.date.accessioned2010-04-01T14:48:13Z
dc.date.available2010-04-01T14:48:13Z
dc.date.issued2007-02en_US
dc.identifier.citationSaraiva, M. C. P.; Taichman, R. S.; Braun, T.; Nriagu, J.; Eklund, S. A.; Burt, B. A. (2007). "Lead exposure and periodontitis in US adults." Journal of Periodontal Research 42(1): 45-52. <http://hdl.handle.net/2027.42/65253>en_US
dc.identifier.issn0022-3484en_US
dc.identifier.issn1600-0765en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/65253
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=17214639&dopt=citationen_US
dc.description.abstractLead is known to have significant effects on bone metabolism and the immune system. This study tested the hypothesis that lead exposure affects periodontitis in adults. Material and Methods:  This study used the data from the Third National Health and Nutrition Examination Survey (NHANES III, 1988–94). It analyzed data from 2500 men and 2399 women, 20–56 yr old, who received complete periodontal examination. Periodontitis was defined as the presence of > 20% of mesial sites with ≥ 4 mm of attachment loss. Lead exposure was grouped into three categories: < 3; 3–7; and > 7 μg/dL. Covariates were cotinine levels, poverty ratio, race/ethnicity, education, bone mineral density, diabetes, calcium intake, dental visit, and menopause (for women). All analyses were performed separately for men and women and considering the effect design. Univariate, bivariate, and stratified analysis was followed by multivariable analysis by estimating prevalence ratios through poisson regression. Results:  After adjustment for confounders, the prevalence ratios, comparing those with a lead blood level of > 7 μg/dL to those with a lead blood level of < 3 μg/dL was 1.70 (95% confidence interval (CI): 1.02, 2.85) for men and 3.80 (95% CI: 1.66, 8.73) for women. Conclusion:  The lead blood level was positively and statistically associated with periodontitis for both men and women. Considering the public health importance of periodontitis and lead exposure, further studies are necessary to confirm this association.en_US
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dc.format.extent3110 bytes
dc.format.mimetypeapplication/pdf
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dc.publisherBlackwell Publishing Ltden_US
dc.rights2007 The Authors. Journal compilation 2007 Blackwell Munksgaarden_US
dc.subject.otherAdultsen_US
dc.subject.otherLead Exposureen_US
dc.subject.otherOral Healthen_US
dc.subject.otherPeriodontitisen_US
dc.subject.otherToxicologyen_US
dc.titleLead exposure and periodontitis in US adultsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelDentistryen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Periodontics and Oral Medicine, Prevention, Geriatrics, School of Dentistry, University of Michigan, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumEpidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USAen_US
dc.contributor.affiliationotherDepartment of Paediatrics and Social Dentistry, School of Dentistry of RibeirÃo Preto, University of SÃo Paulo, SP, Brazilen_US
dc.contributor.affiliationotherBiostatisticsen_US
dc.contributor.affiliationotherEnvironmental Health Scienceen_US
dc.identifier.pmid17214639en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/65253/1/j.1600-0765.2006.00913.x.pdf
dc.identifier.doi10.1111/j.1600-0765.2006.00913.xen_US
dc.identifier.sourceJournal of Periodontal Researchen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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