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Expulsion mechanism of xylitol 5-phosphate in Streptococcus mutans

dc.contributor.authorPihlanto-Leppälä, Anneen_US
dc.contributor.authorSöderling, Evaen_US
dc.contributor.authorMakinen, Kauko K.en_US
dc.date.accessioned2010-06-01T18:34:17Z
dc.date.available2010-06-01T18:34:17Z
dc.date.issued1990-04en_US
dc.identifier.citationPIHLANTO-LEPPÄLÄ, ANNE; SÖDERLING, EVA; MÄKINEN, KAUKO K. (1990). "Expulsion mechanism of xylitol 5-phosphate in Streptococcus mutans." European Journal of Oral Sciences 98(2): 112-119. <http://hdl.handle.net/2027.42/71776>en_US
dc.identifier.issn0909-8836en_US
dc.identifier.issn1600-0722en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/71776
dc.description.abstractThe expulsion mechanism of xylitol 5-phosphate in Streptococcus mutans ATCC 25175 was studied using resting cells incubated in the presence of 14 C-xylitol. The expulsion appeared to be a two-step process: xylitol 5-phosphate was first hydrolyzed to xylitol and inorganic phosphate, and the xylitol was subsequently expelled from the cells. The dephosphorylation step appeared to be energy-requiring and it was most likely associated with a phosphatase which was active on xylitol 5-phosphate. Two to three successive cultivations of the cells in the presence of 6% xylitol increased this enzyme activity 4.3-fold. These results are in accordance with the presence of an energy-dependent xylitol 5-phosphate cycle in S. mutans , which is regulated by exogenous xylitol.en_US
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dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
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dc.publisherBlackwell Publishing Ltden_US
dc.rightsMunksgaard 1990en_US
dc.subject.otherS. Mutansen_US
dc.subject.otherXylitolen_US
dc.titleExpulsion mechanism of xylitol 5-phosphate in Streptococcus mutansen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelDentistryen_US
dc.subject.hlbsecondlevelOtolaryngologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumSchool of Dentistry, The University of Michigan, Ann Arbor, MI, USAen_US
dc.contributor.affiliationotherDepartment of Biochemistry, Institute of Dentistry, Univrsity of Turku, Turku, Finlanden_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/71776/1/j.1600-0722.1990.tb00949.x.pdf
dc.identifier.doi10.1111/j.1600-0722.1990.tb00949.xen_US
dc.identifier.sourceEuropean Journal of Oral Sciencesen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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