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Yersinia effectors target mammalian signalling pathways

dc.contributor.authorJuris, Stephen J.en_US
dc.contributor.authorShao, Fengen_US
dc.contributor.authorDixon, Jack E.en_US
dc.date.accessioned2010-06-01T20:20:58Z
dc.date.available2010-06-01T20:20:58Z
dc.date.issued2002-04en_US
dc.identifier.citationJuris, Stephen J . ; Shao, Feng; Dixon, Jack E . (2002). " Yersinia effectors target mammalian signalling pathways." Cellular Microbiology 4(4): 201-211. <http://hdl.handle.net/2027.42/73466>en_US
dc.identifier.issn1462-5814en_US
dc.identifier.issn1462-5822en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/73466
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=11952637&dopt=citationen_US
dc.description.abstractAnimals have an immune system to fight off challenges from both viruses and bacteria. The first line of defence is innate immunity, which is composed of cells that engulf pathogens as well as cells that release potent signalling molecules to activate an inflammatory response and the adaptive immune system. Pathogenic bacteria have evolved a set of weapons, or effectors, to ensure survival in the host. Yersinia spp. use a type III secretion system to translocate these effector proteins, called Yops, into the host. This report outlines how Yops thwart the signalling machinery of the host immune system.en_US
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dc.publisherBlackwell Science Asia Pty. Ltd.en_US
dc.rightsBlackwell Science Ltden_US
dc.titleYersinia effectors target mammalian signalling pathwaysen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumUniversity of Michigan, 1301 East Catherine, 4433 Medical Science I, Ann Arbor, MI 48109-0606, USA.en_US
dc.identifier.pmid11952637en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/73466/1/j.1462-5822.2002.00182.x.pdf
dc.identifier.doi10.1046/j.1462-5822.2002.00182.xen_US
dc.identifier.sourceCellular Microbiologyen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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