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A novel H28Y mutation in LEC rats leads to decreased NAT protein stability in vivo and in vitro

dc.contributor.authorHuang, Zhepingen_US
dc.contributor.authorDeng, Jieen_US
dc.contributor.authorBorjigin, Jimoen_US
dc.date.accessioned2010-06-01T20:33:20Z
dc.date.available2010-06-01T20:33:20Z
dc.date.issued2005-08en_US
dc.identifier.citationHuang, Zheping; Deng, Jie; Borjigin, Jimo (2005). "A novel H28Y mutation in LEC rats leads to decreased NAT protein stability in vivo and in vitro." Journal of Pineal Research 39(1): 84-90. <http://hdl.handle.net/2027.42/73664>en_US
dc.identifier.issn0742-3098en_US
dc.identifier.issn1600-079Xen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/73664
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=15978062&dopt=citationen_US
dc.format.extent286954 bytes
dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherMunksgaard International Publishersen_US
dc.publisherBlackwell Publishing Ltden_US
dc.rights2005 Blackwell Munksgaarden_US
dc.subject.otherCircadian Rhythmsen_US
dc.subject.otherLong Evans Cinnamon Ratsen_US
dc.subject.otherMelatoninen_US
dc.subject.otherPineal Glanden_US
dc.subject.otherProtein Stabilityen_US
dc.subject.otherSerotonin N-acetyltransferaseen_US
dc.titleA novel H28Y mutation in LEC rats leads to decreased NAT protein stability in vivo and in vitroen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelInternal Medicine and Specialtiesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MIen_US
dc.contributor.affiliationotherDepartment of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USAen_US
dc.identifier.pmid15978062en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/73664/1/j.1600-079X.2005.00222.x.pdf
dc.identifier.doi10.1111/j.1600-079X.2005.00222.xen_US
dc.identifier.sourceJournal of Pineal Researchen_US
dc.identifier.citedreferenceTan DX, Manchester LC, Hardeland R et al. Melatonin: a hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitamin. J Pineal Res 2003; 34: 75 – 78.en_US
dc.identifier.citedreferenceArendt J. Melatonin and the Mammalian Pineal Gland, 1st edn. Chapman & Hall, London and New York, 1995.en_US
dc.identifier.citedreferenceKlein DC, Coon SL, Roseboom PH et al. The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal gland. Rec Prog Horm Res 1997; 52: 305 – 357.en_US
dc.identifier.citedreferenceBorjigin J, Li X, Snyder SH. The pineal gland and melatonin: molecular and pharmacologic regulation. Annu Rev Pharmacol Toxicol 1999; 39: 53 – 65.en_US
dc.identifier.citedreferenceSimonneaux V, Ribelayga C. Generation of the melatonin endocrine message in mammals: a review of the complex regulation of melatonin synthesis by norepinephrine, peptides, and other pineal transmitters. Pharmacol Rev 2003; 55: 325 – 395.en_US
dc.identifier.citedreferenceKlein DC, Weller JL. Indole metabolism in the pineal gland: a circadian rhythm in N-acetyltransferase. Science 1970; 169: 1093 – 1095.en_US
dc.identifier.citedreferenceBorjigin J, Wang MM, Snyder SH. Diurnal variation in mRNA encoding serotonin N-acetyltransferase in pineal gland. Nature 1995; 378: 783 – 785.en_US
dc.identifier.citedreferenceGastel JA, Roseboom PH, Rinaldi PA et al. Melatonin production: proteasomal proteolysis in serotonin N-acetyltransferase regulation. Science 1998; 279: 1358 – 1360.en_US
dc.identifier.citedreferenceBorjigin J, Payne AS, Deng J et al. A novel pineal night-specific ATPase encoded by the Wilson disease gene. J Neurosci 1999; 19: 1018 – 1026.en_US
dc.identifier.citedreferenceBorjigin J, Deng J, Wang MM et al. Circadian rhythm of patched1 transcription in the pineal regulated by adrenergic stimulation and cAMP. J Biol Chem 1999; 274: 35012 – 35015.en_US
dc.identifier.citedreferenceBorjigin J, Deng J, Sun X et al. Diurnal pineal 3-O-sulphotransferase 2 expression controlled by beta-adrenergic repression. J Biol Chem 2003; 278: 16315 – 16319.en_US
dc.identifier.citedreferenceCox DW, Moore SD. Copper transporting P-type ATPases and human disease. J Bioenerg Biomembr 2002; 34: 333 – 338.en_US
dc.identifier.citedreferenceLi X, Chen S, Wang Q et al. A pineal regulatory element (PIRE) mediates transactivation by the pineal/retina-specific transcription factor CRX. Proc Natl Acad Sci U S A 1998; 95: 1876 – 1881.en_US
dc.identifier.citedreferenceYoshida MC, Masuda R, Sasaki M et al. New mutation causing hereditary hepatitis in the laboratory rat. J Heredity 1987; 78: 361 – 365.en_US
dc.identifier.citedreferenceWu J, Forbes JR, Chen HS et al. The LEC rat has a deletion in the copper transporting ATPase gene homologous to the Wilson disease gene. Nat Genet 1994; 7: 541 – 545.en_US
dc.identifier.citedreferenceChampney TH, Holtorf AP, Steger RW et al. Concurrent determination of enzymatic activities and substrate concentrations in the melatonin synthetic pathway within the same rat pineal gland. J Neurosci Res 1984; 11: 59 – 66.en_US
dc.identifier.citedreferenceBorjigin J, Nathans J. Insertional mutagenesis as a probe of rhodopsin's topography, stability, and activity. J Biol Chem 1994; 269: 14715 – 14722.en_US
dc.identifier.citedreferenceLi X. The Regulation of Tissue-Specific and Rhythmic Expression of Serotonin N-acetyltransferase. Neuroscience. The Johns Hopkins University, Baltimore, MD, 2000; pp. 90.en_US
dc.identifier.citedreferenceGanguly S, Gastel JA, Weller JL et al. Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis. Proc Natl Acad Sci U S A 2001; 98: 8083 – 8088.en_US
dc.identifier.citedreferenceObsil T, Ghirlando R, Klein DC et al. Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. A role for scaffolding in enzyme regulation. Cell 2001; 105: 257 – 267.en_US
dc.identifier.citedreferenceKlein DC, Ganguly S, Coon SL et al. 14-3-3 proteins in pineal photoneuroendocrine transduction: how many roles ? J Neuroendocrinol 2003; 15: 370 – 377.en_US
dc.identifier.citedreferenceChoi BH, Chae HD, Park TJ et al. Protein kinase C regulates the activity and stability of serotonin N-acetyltransferase. J Neurochem 2004; 90: 442 – 454.en_US
dc.identifier.citedreferenceRoseboom PH, Coon SL, Baler R et al. Melatonin synthesis: analysis of the more than 150-fold nocturnal increase in serotonin N-acetyltransferase messenger ribonucleic acid in the rat pineal gland. Endocrinology 1996; 137: 3033 – 3045.en_US
dc.identifier.citedreferenceCoon SL, Mazuruk K, Bernard M et al. The human serotonin N-acetyltransferase (EC 2.3.1.87) gene (AANAT): structure, chromosomal localization, and tissue expression. Genomics 1996; 34: 76 – 84.en_US
dc.identifier.citedreferenceCoon SL, Del Olmo E, Young WS, III et al. Melatonin synthesis enzymes in Macaca mulatta: focus on arylalkylamine N-acetyltransferase (EC 2.3.1.87). J Clin Endocrinol Metab 2002; 87: 4699 – 4706.en_US
dc.identifier.citedreferenceCoon SL, Roseboom PH, Baler R et al. Pineal serotonin N-acetyltransferase: expression cloning and molecular analysis. Science 1995; 270: 1681 – 1683.en_US
dc.identifier.citedreferenceGauer F, Poirel VJ, Garidou ML et al. Molecular cloning of the arylalkylamine-N-acetyltransferase and daily variations of its mRNA expression in the Syrian hamster pineal gland. Brain Res Mol Brain Res 1999; 71: 87 – 95.en_US
dc.identifier.citedreferenceSakamoto K, Ishida N. Molecular cloning of serotonin N-acetyltransferase gene from the mouse and its daily expression in the retina. Neurosci Lett 1998; 250: 181 – 184.en_US
dc.identifier.citedreferenceRoseboom PH, Namboodiri MA, Zimonjic DB et al. Natural melatonin ‘knockdown’ in C57BL/6J mice: rare mechanism truncates serotonin N-acetyltransferase. Brain Res Mol Brain Res 1998; 63: 189 – 197.en_US
dc.identifier.citedreferenceBernard M, Iuvone PM, Cassone VM et al. Avian melatonin synthesis: photic and circadian regulation of serotonin N-acetyltransferase mRNA in the chicken pineal gland and retina. J Neurochem 1997; 68: 213 – 224.en_US
dc.identifier.citedreferenceFidler AE, Kuhn S, Gwinner E. Convergent evolution of strigiform and caprimulgiform dark-activity is supported by phylogenetic analysis using the arylalkylamine N-acetyltransferase (AANAT) gene. Mol Phylogenet Evol 2004; 33: 908 – 921.en_US
dc.identifier.citedreferenceZilberman-Peled B, Benhar I, Coon SL et al. Duality of serotonin-N-acetyltransferase in the gilthead seabream ( Sparus aurata ): molecular cloning and characterization of recombinant enzymes. Gen Comp Endocrinol 2004; 138: 139 – 147.en_US
dc.identifier.citedreferenceGothilf Y, Coon SL, Toyama R et al. Zebrafish serotonin N-acetyltransferase-2: marker for development of pineal photoreceptors and circadian clock function. Endocrinology 1999; 140: 4895 – 4903.en_US
dc.identifier.citedreferenceKemp BE, Pearson RB. Protein kinase recognition sequence motifs. Trends Biochem Sci 1990; 15: 342 – 346.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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