A novel H28Y mutation in LEC rats leads to decreased NAT protein stability in vivo and in vitro
dc.contributor.author | Huang, Zheping | en_US |
dc.contributor.author | Deng, Jie | en_US |
dc.contributor.author | Borjigin, Jimo | en_US |
dc.date.accessioned | 2010-06-01T20:33:20Z | |
dc.date.available | 2010-06-01T20:33:20Z | |
dc.date.issued | 2005-08 | en_US |
dc.identifier.citation | Huang, Zheping; Deng, Jie; Borjigin, Jimo (2005). "A novel H28Y mutation in LEC rats leads to decreased NAT protein stability in vivo and in vitro." Journal of Pineal Research 39(1): 84-90. <http://hdl.handle.net/2027.42/73664> | en_US |
dc.identifier.issn | 0742-3098 | en_US |
dc.identifier.issn | 1600-079X | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/73664 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=15978062&dopt=citation | en_US |
dc.format.extent | 286954 bytes | |
dc.format.extent | 3109 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Munksgaard International Publishers | en_US |
dc.publisher | Blackwell Publishing Ltd | en_US |
dc.rights | 2005 Blackwell Munksgaard | en_US |
dc.subject.other | Circadian Rhythms | en_US |
dc.subject.other | Long Evans Cinnamon Rats | en_US |
dc.subject.other | Melatonin | en_US |
dc.subject.other | Pineal Gland | en_US |
dc.subject.other | Protein Stability | en_US |
dc.subject.other | Serotonin N-acetyltransferase | en_US |
dc.title | A novel H28Y mutation in LEC rats leads to decreased NAT protein stability in vivo and in vitro | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI | en_US |
dc.contributor.affiliationother | Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA | en_US |
dc.identifier.pmid | 15978062 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/73664/1/j.1600-079X.2005.00222.x.pdf | |
dc.identifier.doi | 10.1111/j.1600-079X.2005.00222.x | en_US |
dc.identifier.source | Journal of Pineal Research | en_US |
dc.identifier.citedreference | Tan DX, Manchester LC, Hardeland R et al. Melatonin: a hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitamin. J Pineal Res 2003; 34: 75 – 78. | en_US |
dc.identifier.citedreference | Arendt J. Melatonin and the Mammalian Pineal Gland, 1st edn. Chapman & Hall, London and New York, 1995. | en_US |
dc.identifier.citedreference | Klein DC, Coon SL, Roseboom PH et al. The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal gland. Rec Prog Horm Res 1997; 52: 305 – 357. | en_US |
dc.identifier.citedreference | Borjigin J, Li X, Snyder SH. The pineal gland and melatonin: molecular and pharmacologic regulation. Annu Rev Pharmacol Toxicol 1999; 39: 53 – 65. | en_US |
dc.identifier.citedreference | Simonneaux V, Ribelayga C. Generation of the melatonin endocrine message in mammals: a review of the complex regulation of melatonin synthesis by norepinephrine, peptides, and other pineal transmitters. Pharmacol Rev 2003; 55: 325 – 395. | en_US |
dc.identifier.citedreference | Klein DC, Weller JL. Indole metabolism in the pineal gland: a circadian rhythm in N-acetyltransferase. Science 1970; 169: 1093 – 1095. | en_US |
dc.identifier.citedreference | Borjigin J, Wang MM, Snyder SH. Diurnal variation in mRNA encoding serotonin N-acetyltransferase in pineal gland. Nature 1995; 378: 783 – 785. | en_US |
dc.identifier.citedreference | Gastel JA, Roseboom PH, Rinaldi PA et al. Melatonin production: proteasomal proteolysis in serotonin N-acetyltransferase regulation. Science 1998; 279: 1358 – 1360. | en_US |
dc.identifier.citedreference | Borjigin J, Payne AS, Deng J et al. A novel pineal night-specific ATPase encoded by the Wilson disease gene. J Neurosci 1999; 19: 1018 – 1026. | en_US |
dc.identifier.citedreference | Borjigin J, Deng J, Wang MM et al. Circadian rhythm of patched1 transcription in the pineal regulated by adrenergic stimulation and cAMP. J Biol Chem 1999; 274: 35012 – 35015. | en_US |
dc.identifier.citedreference | Borjigin J, Deng J, Sun X et al. Diurnal pineal 3-O-sulphotransferase 2 expression controlled by beta-adrenergic repression. J Biol Chem 2003; 278: 16315 – 16319. | en_US |
dc.identifier.citedreference | Cox DW, Moore SD. Copper transporting P-type ATPases and human disease. J Bioenerg Biomembr 2002; 34: 333 – 338. | en_US |
dc.identifier.citedreference | Li X, Chen S, Wang Q et al. A pineal regulatory element (PIRE) mediates transactivation by the pineal/retina-specific transcription factor CRX. Proc Natl Acad Sci U S A 1998; 95: 1876 – 1881. | en_US |
dc.identifier.citedreference | Yoshida MC, Masuda R, Sasaki M et al. New mutation causing hereditary hepatitis in the laboratory rat. J Heredity 1987; 78: 361 – 365. | en_US |
dc.identifier.citedreference | Wu J, Forbes JR, Chen HS et al. The LEC rat has a deletion in the copper transporting ATPase gene homologous to the Wilson disease gene. Nat Genet 1994; 7: 541 – 545. | en_US |
dc.identifier.citedreference | Champney TH, Holtorf AP, Steger RW et al. Concurrent determination of enzymatic activities and substrate concentrations in the melatonin synthetic pathway within the same rat pineal gland. J Neurosci Res 1984; 11: 59 – 66. | en_US |
dc.identifier.citedreference | Borjigin J, Nathans J. Insertional mutagenesis as a probe of rhodopsin's topography, stability, and activity. J Biol Chem 1994; 269: 14715 – 14722. | en_US |
dc.identifier.citedreference | Li X. The Regulation of Tissue-Specific and Rhythmic Expression of Serotonin N-acetyltransferase. Neuroscience. The Johns Hopkins University, Baltimore, MD, 2000; pp. 90. | en_US |
dc.identifier.citedreference | Ganguly S, Gastel JA, Weller JL et al. Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis. Proc Natl Acad Sci U S A 2001; 98: 8083 – 8088. | en_US |
dc.identifier.citedreference | Obsil T, Ghirlando R, Klein DC et al. Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. A role for scaffolding in enzyme regulation. Cell 2001; 105: 257 – 267. | en_US |
dc.identifier.citedreference | Klein DC, Ganguly S, Coon SL et al. 14-3-3 proteins in pineal photoneuroendocrine transduction: how many roles ? J Neuroendocrinol 2003; 15: 370 – 377. | en_US |
dc.identifier.citedreference | Choi BH, Chae HD, Park TJ et al. Protein kinase C regulates the activity and stability of serotonin N-acetyltransferase. J Neurochem 2004; 90: 442 – 454. | en_US |
dc.identifier.citedreference | Roseboom PH, Coon SL, Baler R et al. Melatonin synthesis: analysis of the more than 150-fold nocturnal increase in serotonin N-acetyltransferase messenger ribonucleic acid in the rat pineal gland. Endocrinology 1996; 137: 3033 – 3045. | en_US |
dc.identifier.citedreference | Coon SL, Mazuruk K, Bernard M et al. The human serotonin N-acetyltransferase (EC 2.3.1.87) gene (AANAT): structure, chromosomal localization, and tissue expression. Genomics 1996; 34: 76 – 84. | en_US |
dc.identifier.citedreference | Coon SL, Del Olmo E, Young WS, III et al. Melatonin synthesis enzymes in Macaca mulatta: focus on arylalkylamine N-acetyltransferase (EC 2.3.1.87). J Clin Endocrinol Metab 2002; 87: 4699 – 4706. | en_US |
dc.identifier.citedreference | Coon SL, Roseboom PH, Baler R et al. Pineal serotonin N-acetyltransferase: expression cloning and molecular analysis. Science 1995; 270: 1681 – 1683. | en_US |
dc.identifier.citedreference | Gauer F, Poirel VJ, Garidou ML et al. Molecular cloning of the arylalkylamine-N-acetyltransferase and daily variations of its mRNA expression in the Syrian hamster pineal gland. Brain Res Mol Brain Res 1999; 71: 87 – 95. | en_US |
dc.identifier.citedreference | Sakamoto K, Ishida N. Molecular cloning of serotonin N-acetyltransferase gene from the mouse and its daily expression in the retina. Neurosci Lett 1998; 250: 181 – 184. | en_US |
dc.identifier.citedreference | Roseboom PH, Namboodiri MA, Zimonjic DB et al. Natural melatonin ‘knockdown’ in C57BL/6J mice: rare mechanism truncates serotonin N-acetyltransferase. Brain Res Mol Brain Res 1998; 63: 189 – 197. | en_US |
dc.identifier.citedreference | Bernard M, Iuvone PM, Cassone VM et al. Avian melatonin synthesis: photic and circadian regulation of serotonin N-acetyltransferase mRNA in the chicken pineal gland and retina. J Neurochem 1997; 68: 213 – 224. | en_US |
dc.identifier.citedreference | Fidler AE, Kuhn S, Gwinner E. Convergent evolution of strigiform and caprimulgiform dark-activity is supported by phylogenetic analysis using the arylalkylamine N-acetyltransferase (AANAT) gene. Mol Phylogenet Evol 2004; 33: 908 – 921. | en_US |
dc.identifier.citedreference | Zilberman-Peled B, Benhar I, Coon SL et al. Duality of serotonin-N-acetyltransferase in the gilthead seabream ( Sparus aurata ): molecular cloning and characterization of recombinant enzymes. Gen Comp Endocrinol 2004; 138: 139 – 147. | en_US |
dc.identifier.citedreference | Gothilf Y, Coon SL, Toyama R et al. Zebrafish serotonin N-acetyltransferase-2: marker for development of pineal photoreceptors and circadian clock function. Endocrinology 1999; 140: 4895 – 4903. | en_US |
dc.identifier.citedreference | Kemp BE, Pearson RB. Protein kinase recognition sequence motifs. Trends Biochem Sci 1990; 15: 342 – 346. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.