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WITHDRAWAL OF ENDOGENOUS SYMPATHETIC DRIVE LOWERS BLOOD PRESSURE IN PRIMARY ALDOSTERONISM

dc.contributor.authorNicholls, M. Garyen_US
dc.contributor.authorJulius, Stevoen_US
dc.contributor.authorZweifler, Andrew J.en_US
dc.date.accessioned2010-06-01T20:40:31Z
dc.date.available2010-06-01T20:40:31Z
dc.date.issued1981-09en_US
dc.identifier.citationNICHOLLS, M. G.; JULIUS, S.; ZWEIFLER, A. J. (1981). "WITHDRAWAL OF ENDOGENOUS SYMPATHETIC DRIVE LOWERS BLOOD PRESSURE IN PRIMARY ALDOSTERONISM." Clinical Endocrinology 15(3): 253-258. <http://hdl.handle.net/2027.42/73780>en_US
dc.identifier.issn0300-0664en_US
dc.identifier.issn1365-2265en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/73780
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6975670&dopt=citationen_US
dc.description.abstractWe were able to observe the effect of withdrawal of endogenous sympathetic drive in a hypertensive patient with an aldosterone-secreting adrenal adenoma. Acute stimulation of both carotid sinus nerves lowered blood pressure to normotensive or hypotensive levels by reducing peripheral resistance. When chronic carotid sinus nerve stimulation was discontinued, peripheral resistance and blood pressure increased. These data suggest that the sympathetic nervous system is important in the maintenance of hypertension in established primary aldosteronism.en_US
dc.format.extent344358 bytes
dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
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dc.publisherBlackwell Publishing Ltden_US
dc.rights1981 Blackwell Scientific Publicationsen_US
dc.titleWITHDRAWAL OF ENDOGENOUS SYMPATHETIC DRIVE LOWERS BLOOD PRESSURE IN PRIMARY ALDOSTERONISMen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelInternal Medicine and Specialtiesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDivision of Hypertension, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, USAen_US
dc.identifier.pmid6975670en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/73780/1/j.1365-2265.1981.tb00663.x.pdf
dc.identifier.doi10.1111/j.1365-2265.1981.tb00663.xen_US
dc.identifier.sourceClinical Endocrinologyen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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