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Neuroimaging Studies of Emotional Responses in PTSD

dc.contributor.authorLiberzon, Israelen_US
dc.contributor.authorMartis, Brianen_US
dc.date.accessioned2010-06-01T21:06:25Z
dc.date.available2010-06-01T21:06:25Z
dc.date.issued2006-07en_US
dc.identifier.citationLIBERZON, ISRAEL; MARTIS, BRIAN (2006). "Neuroimaging Studies of Emotional Responses in PTSD." Annals of the New York Academy of Sciences 1071(1 Psychobiology of Posttraumatic Stress Disorder: A Decade of Progress ): 87-109. <http://hdl.handle.net/2027.42/74195>en_US
dc.identifier.issn0077-8923en_US
dc.identifier.issn1749-6632en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/74195
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=16891565&dopt=citationen_US
dc.description.abstractNeuroimaging research offers a powerful and noninvasive means to understand healthy as well as dysregulated emotional processing in healthy subjects and PTSD patients. Functional neuroimaging findings suggest specific roles for subregions of the medial prefrontal (mPFC), orbito frontal (OFC), anterior cingulate (ACC), and insular cortices as well as the sublenticular extended amygdala (SLEA) and hippocampus in various components of emotional processing. Some of the same regions appear to be associated with emotional response to trauma, and with symptom formation in PTSD. Neuroimaging findings of emotional processing in healthy subjects and PTSD patients are discussed, addressing the specific roles of cortical regions like mPFC, ACC, and insula, and their potential contribution to PTSD pathophysiology. Processes of cognitive–emotional interactions and social emotions are discussed in an attempt to synthesize the prefrontal findings in healthy subjects and PTSD patients. Further links between functional neuroanatomy of emotional responses and neuroendocrine stress regulation are proposed.en_US
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dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
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dc.publisherBlackwell Publishing Incen_US
dc.rights2006 New York Academy of Sciencesen_US
dc.subject.otherPTSDen_US
dc.subject.otherEmotion Regulationen_US
dc.subject.otherNeural Circuitryen_US
dc.subject.otherFunctional Neuroimagingen_US
dc.subject.otherMedial Prefrontal Cortexen_US
dc.subject.otherAnterior Cingulated Cortexen_US
dc.subject.otherAmygdalaen_US
dc.subject.otherHippocampusen_US
dc.titleNeuroimaging Studies of Emotional Responses in PTSDen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelScience (General)en_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumTrauma Stress and Anxiety Research Group, VA Ann Arbor Healthcare System, Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109-0118, USAen_US
dc.identifier.pmid16891565en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/74195/1/annals.1364.009.pdf
dc.identifier.doi10.1196/annals.1364.009en_US
dc.identifier.sourceAnnals of the New York Academy of Sciencesen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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