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Dynamic increases in dopamine during paced copulation in the female rat

dc.contributor.authorJenkins, William J.en_US
dc.contributor.authorBecker, Jill B.en_US
dc.date.accessioned2010-06-01T21:10:29Z
dc.date.available2010-06-01T21:10:29Z
dc.date.issued2003-10en_US
dc.identifier.citationJenkins, William J.; Becker, Jill B. (2003). "Dynamic increases in dopamine during paced copulation in the female rat." European Journal of Neuroscience 18(7): 1997-2001. <http://hdl.handle.net/2027.42/74256>en_US
dc.identifier.issn0953-816Xen_US
dc.identifier.issn1460-9568en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/74256
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=14622232&dopt=citationen_US
dc.description.abstractThe role of dopamine in the rewarding aspects of sexual behaviour in female rats was investigated. This is a unique model because sexual behaviour is only rewarding when copulatory stimuli are experienced at the preferred rate of copulation for a female rat. In addition, increases in dopamine in the nucleus accumbens occur during sexual behaviour only when the female achieves this preferred rate of copulation. In this study, minute-by-minute changes in nucleus accumbens dopamine were monitored using in vivo microdialysis. We report here that extracellular dopamine in the nucleus accumbens increases before coital stimulation only when sexual behaviour is occurring under conditions that are rewarding to the female rat. We conclude that increases in dopamine in the nucleus accumbens are involved in anticipation, not consummation, of sexual behaviour in the female rat.en_US
dc.format.extent107211 bytes
dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
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dc.publisherBlackwell Science, Ltden_US
dc.rights© Federation of European Neuroscience Societiesen_US
dc.subject.otherDopamineen_US
dc.subject.otherIntromissionen_US
dc.subject.otherNucleus Accumbensen_US
dc.subject.otherSexual Behaviouren_US
dc.titleDynamic increases in dopamine during paced copulation in the female raten_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumNeuroscience Program, University of Michigan, 525 E. University, Ann Arbor, MI 48109–1109 USAen_US
dc.contributor.affiliationotherDepartment of Psychology, Reproductive Sciences Program, anden_US
dc.identifier.pmid14622232en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/74256/1/j.1460-9568.2003.02923.x.pdf
dc.identifier.doi10.1046/j.1460-9568.2003.02923.xen_US
dc.identifier.sourceEuropean Journal of Neuroscienceen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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