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Orphanin FQ inhibits capsaicin-induced thermal nociception in monkeys by activation of peripheral ORL1 receptors

dc.contributor.authorKo, M. C. Holdenen_US
dc.contributor.authorNaughton, N. N.en_US
dc.contributor.authorTraynor, John R.en_US
dc.contributor.authorSong, M. S.en_US
dc.contributor.authorWoods, James H.en_US
dc.contributor.authorRice, Kenner C.en_US
dc.contributor.authorMcKnight, A. T.en_US
dc.date.accessioned2010-06-01T21:21:16Z
dc.date.available2010-06-01T21:21:16Z
dc.date.issued2002-02en_US
dc.identifier.citationKo, M C H; Naughton, N N; Traynor, J R; Song, M S; Woods, J H; Rice, K C; McKnight, A T (2002). "Orphanin FQ inhibits capsaicin-induced thermal nociception in monkeys by activation of peripheral ORL1 receptors." British Journal of Pharmacology 135(4): 943-950. <http://hdl.handle.net/2027.42/74419>en_US
dc.identifier.issn0007-1188en_US
dc.identifier.issn1476-5381en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/74419
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=11861322&dopt=citationen_US
dc.format.extent286913 bytes
dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.rights2002 British Pharmacological Societyen_US
dc.subject.otherAntinociceptionen_US
dc.subject.otherOrphanin FQen_US
dc.subject.otherORL1 Receptorsen_US
dc.subject.otherCapsaicinen_US
dc.subject.otherPeripheral Tissuesen_US
dc.subject.otherPrimary Afferent Nociceptorsen_US
dc.subject.otherHyperalgesiaen_US
dc.titleOrphanin FQ inhibits capsaicin-induced thermal nociception in monkeys by activation of peripheral ORL1 receptorsen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationotherOxford Natural Products, Charlbury, Oxfordshireen_US
dc.identifier.pmid11861322en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/74419/1/sj.bjp.0704535.pdf
dc.identifier.doi10.1038/sj.bjp.0704535en_US
dc.identifier.sourceBritish Journal of Pharmacologyen_US
dc.identifier.citedreferenceANDREEV, N., URBAN, L. & DRAY, A. ( 1994 ). Opioids suppress spontaneous activity of polymodal nociceptors in rat paw skin induced by ultraviolet irradiation. Neuroscience, 58, 793 – 798.en_US
dc.identifier.citedreferenceANTONIJEVIC, I., MOUSA, S.A., SCHAFER, M. & STEIN, C. ( 1995 ). Perineurial defect and peripheral opioid analgesia in inflammation. J. Neurosci., 15, 165 – 172.en_US
dc.identifier.citedreferenceBARTHÓ, L., STEIN, C. & HERZ, A. ( 1990 ). Involvement of capsaicin-sensitive neurones in hyperalgesia and enhanced opioid antinociception in inflammation. Naunyn-Schmiedeberg's Arch. Pharmacol., 342, 666 – 670.en_US
dc.identifier.citedreferenceBUTELMAN, E.R., NEGUS, S.S., GATCH, M.B., CHANG, K.J. & WOODS, J.H. ( 1995 ). BW373U86, a d-opioid receptor agonist, reverses bradykinin-induced thermal allodynia in rhesus monkeys. Eur. J. Pharmacol., 277, 285 – 287.en_US
dc.identifier.citedreferenceCALO, G., GUERRINI, R., RIZZI, A., SALVADORI, S. & REGOLI, D. ( 2000 ). Pharmacology of nociceptin and its receptor: a novel therapeutic target. Br. J. Pharmacol., 129, 1261 – 1283.en_US
dc.identifier.citedreferenceCATERINA, M.J., LEFFLER, A., MALMBERG, A.B., MARTIN, W.J., TRAFTON, J., PETERSEN-ZEITZ, K.R., KOLTZENBURG, M., BASBAUM, A.I. & JULIUS, D. ( 2000 ). Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science, 288, 306 – 313.en_US
dc.identifier.citedreferenceCATERINA, M.J., SCHUMACHER, M.A., TOMINAGA, M., ROSEN, T.A., LEVINE, J.D. & JULIUS, D. ( 1997 ). The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature, 389, 816 – 824.en_US
dc.identifier.citedreferenceCONNOR, M., YEO, A. & HENDERSON, G. ( 1996 ). The effect of nociceptin on Ca2+ channel current and intracellular Ca2+ in the SH-SY5Y human neuroblastoma cell line. Br. J. Pharmacol., 118, 205 – 207.en_US
dc.identifier.citedreferenceDARLAND, T., HEINRICHER, M.M. & GRANDY, D.K. ( 1998 ). Orphanin FQ/nociceptin: a role in pain and analgesia, but so much more. Trends Neurosci., 21, 215 – 221.en_US
dc.identifier.citedreferenceDAUTZENBERG, F.M., WICHMANN, J., HIGELIN, J., PY-LANG, G., KRATZEISEN, C., MALHERBE, P., KILPATRICK, G.J. & JENCK, F. ( 2001 ). Pharmacological characterization of the novel nonpeptide orphanin FQ/nociceptin receptor agonist Ro 64-6198: rapid and reversible desensitization of the ORL1 receptor in vitro and lack of tolerance in vivo. J. Pharmacol. Exp. Ther., 298, 812 – 819.en_US
dc.identifier.citedreferenceDAVIS, J.B., GRAY, J., GUNTHORPE, M.J., HATCHER, J.P., DAVEY, P.T., OVEREND, P., HARRIES, M.H., LATCHAM, J., CLAPHAM, C., ATKINSON, K., HUGHES, S.A., RANCE, K., GRAU, E., HARPER, A.J., PUGH, P.L., ROGERS, D.C., BINGHAM, S., RANDALL, A. & SHEARDOWN, S.A. ( 2000 ). Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. Nature, 405, 183 – 187.en_US
dc.identifier.citedreferenceEISENACH, J.C., HOOD, D.D., CURRY, R. & TONG, C. ( 1997 ). Alfentanil, but not amitriptyline, redices pain, hyperalgesia, and allodynia from intradermal injection of capsaicin in humans. Anesthesiology, 86, 1279 – 1287.en_US
dc.identifier.citedreferenceGIULIANI, S. & MAGGI, C.A. ( 1996 ). Inhibition of tachykinin release from peripheral endings of sensory nerves by nociceptin, a novel opioid peptide. Br. J. Pharmacol., 118, 1567 – 1569.en_US
dc.identifier.citedreferenceGIULIANI, S. & MAGGI, C.A. ( 1997 ). Prejunctional modulation by nociceptin of nerve-mediated inotropic responses in guinea-pig left atrium. Eur. J. Pharmacol., 332, 231 – 236.en_US
dc.identifier.citedreferenceHALEY, J., KETCHUM, S. & DICKENSON, A. ( 1990 ). Peripheral k-opioid modulation of the formalin response: an electrophysiological study in the rat. Eur. J. Pharmacol., 191, 437 – 446.en_US
dc.identifier.citedreferenceHASHIBA, E., HARRISON, C., GALO, G., GUERRINI, R., ROWBOTHAM, D.J., SMITH, G. & LAMBERT, D.G. ( 2001 ). Characterisation and comparison of novel ligands for the nociceptin/orphanin FQ receptor. Naunyn Schmiedebergs Arch Pharmacol., 363, 28 – 33.en_US
dc.identifier.citedreferenceHELYES, Z., NEMETH, J., PINTER, E. & SZOLCSANYI, J. ( 1997 ). Inhibition by nociceptin of neurogenic inflammation and the release of SP and CGRP from sensory nerve terminals. Br. J. Pharmacol., 121, 613 – 615.en_US
dc.identifier.citedreferenceHENDERSON, G. & MCKNIGHT, A.T. ( 1997 ). The orphan opioid receptor and its endogenous ligand–nociceptin/orphanin FQ. Trends Pharmacol. Sci., 18, 293 – 300.en_US
dc.identifier.citedreferenceHONORE, P., BURITOVA, J. & BESSON, J.M. ( 1996 ). Intraplantar morphine depresses spinal c-Fos expression induced by carrageenin inflammation but not by noxious heat. Br. J. Pharmacol., 118, 671 – 680.en_US
dc.identifier.citedreferenceJENNINGS, E.A. ( 2001 ). Postsynaptic K+ current induced by nociceptin in medullary dorsal horn neurons. Neuroreport, 12, 645 – 648.en_US
dc.identifier.citedreferenceKAWAMOTO, H., OZAKI, S., ITOH, Y., MIYAJI, M., ARAI, S., NAKASHIMA, H., KATO, T., OHTA, H. & IWASAWA, Y. ( 1999 ). Discovery of the first potent and selective small molecule opioid receptor-like (ORL1) antagonist: 1-[(3R,4R)-1-cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl-1, 3-dihydro-2H-benzimidazol-2-one (J-113397). J. Med. Chem., 42, 5061 – 5063.en_US
dc.identifier.citedreferenceKIM, Y.I., NA, H.S., HAN, J.S. & HONG, S.K. ( 1995 ). Critical role of the capsaicin-sensitive nerve fibers in the development of the causalgic symptoms produced by transecting some but not all of the nerves innervating the rat tail. J. Neurosci., 15, 4133 – 4139.en_US
dc.identifier.citedreferenceKNOFLACH, F., REINSCHEID, R.K., CIVELLI, O. & KEMP, J.A. ( 1996 ). Modulation of voltage-gated calcium channels by orphanin FQ in freshly dissociated hippocampal neurons. J. Neurosci., 16, 6657 – 6664.en_US
dc.identifier.citedreferenceKO, M.C., BUTELMAN, E.R. & WOODS, J.H. ( 1998 ). The role of peripheral mu opioid receptors in the modulation of capsaicin-induced thermal nociception in rhesus monkeys. J. Pharmacol. Exp. Ther., 286, 150 – 156.en_US
dc.identifier.citedreferenceKO, M.C., BUTELMAN, E.R. & WOODS, J.H. ( 1999a ). Activation of peripheral kappa opioid receptors inhibits capsaicin- induced thermal nociception in rhesus monkeys. J. Pharmacol. Exp. Ther., 289, 378 – 385.en_US
dc.identifier.citedreferenceKO, M.C.H., JOHNSON, M.D., BUTELMAN, E.R., WILLMONT, K.J., MOSBERG, H.I. & WOODS, J.H. ( 1999b ). Intracisternal nor-binaltorphimine distinguishes central and peripheral kappa-opioid antinociception in rhesus monkeys. J. Pharmacol. Exp. Ther., 291, 1113 – 1120.en_US
dc.identifier.citedreferenceKO, M.C.H., WILLMONT, K.J., BURRITT, A., HRUBY, V.J. & WOODS, J.H. ( 2000 ). Local inhibitory effects of dynorphin A-(1-17) on capsaicin-induced thermal allodynia in rhesus monkeys. Eur. J. Pharmacol., 402, 69 – 76.en_US
dc.identifier.citedreferenceLAMOTTE, R.H., LUNDBERG, L.E.R. & TOREBJORK, H.E. ( 1992 ). Pain, hyperalgesia and activity in nociceptive C units in humans after intradermal injection of capsaicin. J. Physiol., 448, 749 – 764.en_US
dc.identifier.citedreferenceMEUNIER, J.-C., MOLLEREAU, C., TOLL, L., SUAUDEAU, C., MOISAND, C., ALVINERIE, P., BUTOUR, J.-L., GUILLEMOT, J.-C., FERRARA, P., MONSARRAT, B., MAZARGULL, H., VASSART, G., PARMENTIER, M. & COSTENTIN, J. ( 1995 ). Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature, 377, 532 – 535.en_US
dc.identifier.citedreferenceMOLLEREAU, C., PARMENTIER, M., MAILLEUX, P., BUTOUR, J.L., MOISAND, C., CHALON, P., CAPUT, D., VASSART, G. & MEUNIER, J.C. ( 1994 ). ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization. FEBS Lett., 341, 33 – 38.en_US
dc.identifier.citedreferenceNAGASAKA, H., AWAD, H. & YAKSH, T.L. ( 1996 ). Peripheral and spinal actions of opioids in the blockade of the autonomic response evoked by compression of the inflamed knee joint. Anesthesiology, 85, 808 – 816.en_US
dc.identifier.citedreferenceOZAKI, S., KAWAMOTO, H., ITOH, Y., MIYAJI, M., AZUMA, T., ICHIKAWA, D., NAMBU, H., IGUCHI, T., IWASAWA, Y. & OHTA, H. ( 2000 ). In vitro and in vivo pharmacological characterization of J-113397, a potent and selective non-peptidyl ORL1 receptor antagonist. Eur. J. Pharmacol., 402, 45 – 53.en_US
dc.identifier.citedreferenceRAJA, S.N., MEYER, R.A., CAMPBELL, J.N. & KHAN, A.A. ( 1986 ). Narcotics do not alter the heat response of unmyelinated primary afferents in monkeys. Anesthesiology, 65, 468 – 473.en_US
dc.identifier.citedreferenceREINSCHEID, R.K., NOTHACKER, H.-P., BOURSON, A., ARDATI, A., HENNINGSEN, R.A., BUNZOW, J.R., GRANDY, D.K., LANGEN, H., MONSMA JR, F.J. & CIVELLI, O. ( 1995 ). Orphanin FQ: A neuropeptide that activates an opioidlike G protein-coupled receptor. Science, 270, 792 – 794.en_US
dc.identifier.citedreferenceRUSSELL, N.J.W., SCHAIBLE, H.-G. & SCHMIDT, R.F. ( 1987 ). Opiates inhibit the discharges of fine afferent units from inflamed knee joint of the cat. Neurosci. Lett., 76, 107 – 112.en_US
dc.identifier.citedreferenceSENAMI, M., AOKI, M., KITAHATA, L.M., COLLINS, J.G., KUMETA, Y. & MURATA, K. ( 1986 ). Lack of opiate effects on cat C ploymodal nociceptive fibers. Pain, 27, 81 – 90.en_US
dc.identifier.citedreferenceSIMONE, D.A., BAUMANN, T.K. & LAMOTTE, R.H. ( 1989 ). Dose-dependent pain and mechanical hyperalgesia in humans after intradermal injection of capsaicin. Pain, 38, 99 – 107.en_US
dc.identifier.citedreferenceSTEIN, C., MILLAN, M.J., SHIPPENBERG, T.S., PETER, K. & HERZ, A. ( 1989 ). Peripheral opioid receptors mediating antinociception in inflammation. Evidence for involvement of mu, delta and kappa receptors. J. Pharmacol. Exp. Ther., 248, 1269 – 1275.en_US
dc.identifier.citedreferenceSZALLASI, A. & BLUMBERG, P.M. ( 1999 ). Vanilloid (Capsaicin) receptors and mechanisms. Pharmacol. Rev., 51, 159 – 212.en_US
dc.identifier.citedreferenceVAUGHAN, C.W. & CHRISTIE, M.J. ( 1996 ). Increase by the ORL1 receptor (opioid receptor-like1) ligand, nociceptin, of inwardly rectifying K conductance in dorsal raphe nucleus neurones. Br. J. Pharmacol., 117, 1609 – 1611.en_US
dc.identifier.citedreferenceWINTER, J., BEVAN, S. & CAMPBELL, E.A. ( 1995 ). Capsaicin and pain mechanisms. Br. J. Anaesth., 75, 157 – 168.en_US
dc.identifier.citedreferenceYONEHARA, N., IMAI, Y., CHEN, J.-Q., TAKIUCHI, S. & INOKI, R. ( 1992 ). Influence of opioids on substance P release evoked by antidromic stimulation of primary afferent fibers in the hind instep of rats. Reg. Pept., 38, 13 – 22.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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