EVIDENCE FOR OVERDOMINANT SELECTION MAINTAINING X-LINKED FITNESS VARIATION IN DROSOPHILA MELANOGASTER
dc.contributor.author | Connallon, Tim | en_US |
dc.contributor.author | Knowles, L. Lacey | en_US |
dc.date.accessioned | 2010-06-01T22:27:07Z | |
dc.date.available | 2010-06-01T22:27:07Z | |
dc.date.issued | 2006-07 | en_US |
dc.identifier.citation | Connallon, Tim; Knowles, L. Lacey (2006). "EVIDENCE FOR OVERDOMINANT SELECTION MAINTAINING X-LINKED FITNESS VARIATION IN DROSOPHILA MELANOGASTER ." Evolution 60(7): 1445-1453. <http://hdl.handle.net/2027.42/75442> | en_US |
dc.identifier.issn | 0014-3820 | en_US |
dc.identifier.issn | 1558-5646 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/75442 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=16929661&dopt=citation | en_US |
dc.description.abstract | The role of balancing selection in maintaining genetic variation for fitness is largely unresolved. This reflects the inherent difficult in distinguishing between models of recurrent mutation versus selection, which produce similar patterns of inbreeding depression, as well as the limitations of testing such hypotheses when fitness variation is averaged across the genome. Signatures of X-linked overdominant selection are less likely to be obscured by mutational variation because X-linked mutations are rapidly eliminated by purifying selection in males. Although models maintaining genetic variation for fitness are not necessarily mutually exlusive, a series of predictins for identifying X-linked overdominant selection can be used to separate its contribution from other underlying processes. We consider the role of overdominant selection in maintaining fitness variation in a sample of 12 X chromosomes from a population of Drosophila melanogaster. Substantial variation was observed for male reproductive success and female fecundity, with heterozygous-X genotypes exhibiting the greatest gegree of variance, a finding that agress well with predictions of the overdominance model. The importance of X-linked overdominant selection is discussed along with models of recurrent mutation and sexually antagonistic selection. | en_US |
dc.format.extent | 133054 bytes | |
dc.format.extent | 3109 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Blackwell Publishing Ltd | en_US |
dc.rights | 2006 The Society for the Study of Evolution | en_US |
dc.subject.other | Balancing Selection | en_US |
dc.subject.other | Fitness Variation | en_US |
dc.subject.other | Overdominant Selection | en_US |
dc.subject.other | Sex-by-Genotype Interaction | en_US |
dc.subject.other | Sexual Antagonism | en_US |
dc.subject.other | X Chromosome | en_US |
dc.title | EVIDENCE FOR OVERDOMINANT SELECTION MAINTAINING X-LINKED FITNESS VARIATION IN DROSOPHILA MELANOGASTER | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Ecology of Evolutionary Biology and Museum of Zoology, 2019 Natural Science Building, 830 North Unversity, University of Michigan, Ann Arbor, Michigan 48109-1048 | en_US |
dc.identifier.pmid | 16929661 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/75442/1/j.0014-3820.2006.tb01223.x.pdf | |
dc.identifier.doi | 10.1111/j.0014-3820.2006.tb01223.x | en_US |
dc.identifier.source | Evolution | en_US |
dc.identifier.citedreference | Aulard, S., J. R. David, and F. Lemeunier. 2002. Chromosomal inversion polymorphism in Afrotropical populations of Drosophila melanogaster. Genet. Res. 79: 79 – 63. | en_US |
dc.identifier.citedreference | Bateman, A. J. 1948. Intrasexual selection in Drosophila. Heredity 2: 349 – 368. | en_US |
dc.identifier.citedreference | Betancourt, A. J., Y. Kim, and H. A. Orr. 2004. A pseudohitchhiking model of X vs. autosomal diversity. Genetics 168: 2261 – 2269. | en_US |
dc.identifier.citedreference | Charlesworth, B., and D. Charlesworth. 1999. The genetic basis of inbreeding depression. Genet. Res. 74: 329 – 340. | en_US |
dc.identifier.citedreference | Charlesworth, B., and K. A. Hughes. 1999. The maintenance of genetic variation in life-history traits. Pp. 369 – 392 in R. S. Singh and C. B. Krimbas, eds. Evolutionary genetics: from molecules to morphology, 1. Cambridge Univ. Press, Cambridge, U.K. | en_US |
dc.identifier.citedreference | Charlesworth, D., and B. Charlesworth. 1987. Inbreeding depression and its evolutionary consequences. Annu. Rev. Ecol. Syst. 18: 237 – 268. | en_US |
dc.identifier.citedreference | Chippindale, A. K., J. R. Gibson, and W. R. Rice. 2001. Negative genetic correlation for adult fitness between sexes reveals ontogenetic togenetic conflict in Drosophila. Proc. Natl. Acad. Sci. USA 98: 1671 – 1675. | en_US |
dc.identifier.citedreference | Crow, J. F. 1993. Mutation, mean fitness, and genetic load. Pp. 3 – 42, in D. Futuyma and J. Antovics, eds. Oxford surveys in evolutionary biology. 9. Oxford Univ. Press, New York. | en_US |
dc.identifier.citedreference | Crozier, R. H. 1976. Why male-haploid and sex-linked genetic systems seem to have unusually sex-limited mutational genetic loads. Evolution 30: 623 – 624. | en_US |
dc.identifier.citedreference | Eanes, W. F., J. Hey, and D. Houle. 1985. Homozygous and hemizygous viability variation on the X chromosome of Drosophila melanogaster. Genetics 111: 831 – 844. | en_US |
dc.identifier.citedreference | Falconer, D. S., and T. F. C. Mackay. 1996. Introduction to quantitative genetics. 4th ed. Longman, Essex, U.K. | en_US |
dc.identifier.citedreference | Fisher, R. A. 1922. On the dominance ratio. Proc. R. Soc. Edinburgh 52: 312 – 341. | en_US |
dc.identifier.citedreference | Fry, J. D. 2004. On the rate and linearity of viability declines in Drosophila mutation-accumulation experiments: genomic mutation rates and synergistic epistasis revisited. Genetics 166: 797 – 806. | en_US |
dc.identifier.citedreference | Gardner, M. P., K. Fowler, N. H. Barton, and L. Partridge. 2005. Genetic variation for total fitness in Drosophila melanogaster: complex yet replicable patterns. Genetics 169: 1553 – 1571. | en_US |
dc.identifier.citedreference | Gibson, J. R., A. K. Chippindale, and W. R. Rice. 2002. The X chromosome is a hot spot for sexually antagonistic fitness variation. Proc. R. Soc. Lond. B 269: 499 – 505. | en_US |
dc.identifier.citedreference | Greenberg, R., and J. F. Crow. 1960. A comparison of the effect of lethal and detrimental chromosomes from Drosophila populations. Genetics 45: 1153 – 1163. | en_US |
dc.identifier.citedreference | Hartl, D. L., and A. G. Clark. 1997. Principles of population genetics. 3rd ed. Sinauer, Sunderland, MA. | en_US |
dc.identifier.citedreference | Hedrick, P. W. 1985. Genetics of populations. Jones and Bartlett, Boston, MA. | en_US |
dc.identifier.citedreference | Hedrick, P. W., and J. D. Parker. 1997. Evolutionary genetics and genetic variation of haplodiploids and X-linked genes. Annu. Rev. Ecol. Syst. 28: 55 – 83. | en_US |
dc.identifier.citedreference | Holland, B. and W. R. Rice. 1999. Experimental removal of sexual selection reverses intersexual antagonistic coevolution and removes a reproductive load. Proc. Natl. Acad. Sci. USA 96: 5083 – 5088. | en_US |
dc.identifier.citedreference | Houle, D., and L. Rowe. 2003. Natural selection in a bottle. Am. Nat. 161: 50 – 67. | en_US |
dc.identifier.citedreference | Hughes, K. A., and B. Charlesworth. 1994. A genetic analysis of senescence in Drosophila. Nature 367: 64 – 66. | en_US |
dc.identifier.citedreference | James, J. W. 1973. Covariances between relatives due to sex-linked genes. Biometrics 29: 584 – 588. | en_US |
dc.identifier.citedreference | Lewontin, R. C. 1974. The genetic basis of evolutionary change. Columbia Univ. Press, New York. | en_US |
dc.identifier.citedreference | Medawar, P. B. 1952. An unsolved problem of biology. Lewis, London. | en_US |
dc.identifier.citedreference | Mukai, T. 1969. Genetic structure of natural populations of Drosophila melanogaster. 7. Synergistic interaction of spontaneous mutant polygenes controlling viability. Genetics 61: 749 – 1969. | en_US |
dc.identifier.citedreference | Mukai, T., and O. Yamaguchi. 1974. The genetic structure of natural populations of Drosophila melanogaster. XI. Genetic variability in a local population. Genetics 76: 339 – 366. | en_US |
dc.identifier.citedreference | O'Brien, R. G. 1981. A simple test for variance effects in experimental designs. Psych. Bull. 89: 570 – 574. | en_US |
dc.identifier.citedreference | Pamilo, P. 1979. Genic variation at sex-linked loci: quantification of regular selection models. Hereditas 91: 129 – 133. | en_US |
dc.identifier.citedreference | Parisi, M., R. Nuttall, D. Naiman, G. Bouffard, J. Malley, J. Andrews, S. Eastman, and B. Oliver. 2003. Paucity of genes on the Drosophila X chromosome showing male-biased expression. Science 299: 697 – 700. | en_US |
dc.identifier.citedreference | Partridge, L. 1980. Mate choice increases a component of offspring fitness in fruit flies. Nature 283: 290 – 291. | en_US |
dc.identifier.citedreference | Promislow, D. E. L., M. Tatar, A. Khazaeli, and J. W. Curtsinger. 1996. Age-specific patterns of genetic variance in Drosophila melanogaster. I. Mortality. Genetics 143: 839 – 848. | en_US |
dc.identifier.citedreference | Ranz, J. M., C. I. Castillo-Davis, C. D. Meiklejohn, and D. L. Hartl. 2003. Sex-dependent gene expression and evolution of the Drosophila transcriptome. Science 300: 1742 – 1745. | en_US |
dc.identifier.citedreference | Rice, W. R. 1984. Sex chromosomes and the evolution of sexual dimorphism. Evolution 38: 735 – 742. | en_US |
dc.identifier.citedreference | Rice, W. R. 2002. Experimental tests of the adaptive significance of sexual recombination. Nat. Rev. Genet. 3: 241 – 251. | en_US |
dc.identifier.citedreference | Rosa, J. M., S. Camacho, and A. Garcia-Dorado. 2005. A measure of the within-chromosopme epistasis of Drosophila viability. J. Evol. Biol. 18: 1130 – 1137. | en_US |
dc.identifier.citedreference | Saccheri, I. J., H. D. Lloyd, S. J. Helyar, and P. M. Brakefield. 2005. Inbreeding uncovers fundamental differences in the genetic load affecting male and female fertility in a butterfly. Proc. R. Soc. Lond. B 272: 39 – 46. | en_US |
dc.identifier.citedreference | Simmons, M. J., and J. F. Crow. 1977. Mutations affecting fitness in Drosophila populations. Ann. Rev. Genet. 11: 48 – 78. | en_US |
dc.identifier.citedreference | Sokal, R. R., and F. J. Rohlf. 1995. Biometry. 3rd ed. W. H. Freeman, New York. | en_US |
dc.identifier.citedreference | Tracey, M. L., and F. J. Ayala. 1974. Genetic load in natural populations: is it compatible with the hypothesis that many polymorphisms are maintained by natural selection ? Genetics 77: 569 – 589. | en_US |
dc.identifier.citedreference | Trivers, R. L. 1972. Parental investment and reproductive success. Pp. 136 – 179 in B. Campbel, ed. Sexual selection and the descent of man. Aldine-Atherton, Chicago. | en_US |
dc.identifier.citedreference | Wilton, A. D., and J. A. Sved. 1979. X chromosomal heterosis in Drosophila melanogaster. Genet. Res. 34: 303 – 315. | en_US |
dc.identifier.citedreference | Zeh, J. A., and D. W. Zeh. 1996. The evolution of polyandry. I. Intragenomic conflict and genetic incompatibility. Proc. R. Soc. Lond. B 263: 1711 – 1717. | en_US |
dc.identifier.citedreference | Zhang, X.-S., and W. G. Hill. 2005. Genetic variability under mutation selection balance. Trends Ecol. Evol. 20: 468 – 470. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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