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Prospective, Randomized, Controlled Trial of Tissue Adhesive (2-Octylcyanoacrylate) vs Standard Wound Closure Techniques for Laceration Repair

dc.contributor.authorSinger, Adam J.en_US
dc.contributor.authorHollander, Judd E.en_US
dc.contributor.authorValentine, Sharon M.en_US
dc.contributor.authorTurque, Theo W.en_US
dc.contributor.authorMcCuskey, Charles F.en_US
dc.contributor.authorQuinn, James V.en_US
dc.date.accessioned2010-06-01T22:36:10Z
dc.date.available2010-06-01T22:36:10Z
dc.date.issued1998-02en_US
dc.identifier.citationSinger, Adam J.; Hollander, Judd E.; Valentine, Sharon M.; Turque, Theo W.; McCuskey, Charles F.; Quinn, James V. (1998). "Prospective, Randomized, Controlled Trial of Tissue Adhesive (2-Octylcyanoacrylate) vs Standard Wound Closure Techniques for Laceration Repair." Academic Emergency Medicine 5(2): 94-99. <http://hdl.handle.net/2027.42/75580>en_US
dc.identifier.issn1069-6563en_US
dc.identifier.issn1553-2712en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/75580
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9492126&dopt=citationen_US
dc.description.abstractObjective: To compare a new tissue adhesive, 2-octylcyanoacrylate, with standard wound closure techniques for the repair of traumatic lacerations. Methods: A prospective, randomized, controlled clinical trial enrolled consecutive patients >1 year of age with non-bite, non-crush-induced lacerations who presented <6 hours after injury. Structured closed-question data sheets were completed at the time of laceration repair and suture removal. Patients were randomly assigned to treatment with either 2-octylcyanoacrylate or standard wound closure. Infection was determined at the time of suture removal. Long-term cosmetic appearance (>3 months) was assessed by physicians using a previously validated categorical cosmetic scale and by patients using a 100-mm visual analog scale. Results : There were 63 patients randomized to the octylcyanoacrylate group and 61 patients treated with standard wound closure techniques. The 2 treatment groups were similar with respect to age, gender, race, medical history, and wound characteristics. At the 5-to-10-day follow-up, only 1 wound was infected and only 2 wounds required reclosure due to dehiscence. These 3 patients received treatment with octylcyanoacrylate. At long-term follow-up, the cosmetic appearances were similar according to the patients (octylcyanoacrylate, 83.8 ± 19.4 mm vs standard techniques, 82.5 ± 17.6 mm; p = 0.72) and the physicians (optimal cosmetic appearance, 77% vs 80%; p = 0.67). Conclusions: Wounds treated with octylcyanoacrylate and standard wound closure techniques have similar cosmetic appearances 3 months later.en_US
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dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
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dc.publisherBlackwell Publishing Ltden_US
dc.rights1998 Society for Academic Emergency Medicineen_US
dc.subject.otherLacerationsen_US
dc.subject.otherTissue Adhesivesen_US
dc.subject.otherSuturesen_US
dc.subject.otherStaplesen_US
dc.subject.otherInfectionen_US
dc.subject.otherCosmetic Appearanceen_US
dc.subject.otherCyano-acrylateen_US
dc.subject.otherOctylcyanoacrylateen_US
dc.titleProspective, Randomized, Controlled Trial of Tissue Adhesive (2-Octylcyanoacrylate) vs Standard Wound Closure Techniques for Laceration Repairen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelMedicine (General)en_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumUniversity of Michigan, Ann Arbor, Ml, Department of Surgery, Division of Emergency Medicineen_US
dc.contributor.affiliationotherState University of New York at Stony Brook, University Medical Center, Stony Brook, NY, Department of Emergency Medicineen_US
dc.contributor.affiliationotherUniversity of Ottawa, Ottawa, Ontario, Canada, Division of Emergency Medicineen_US
dc.contributor.affiliationotherHospital of the University of Pennsylvania, Philadelphia, PA, Department of Emergency Medicineen_US
dc.identifier.pmid9492126en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/75580/1/j.1553-2712.1998.tb02590.x.pdf
dc.identifier.doi10.1111/j.1553-2712.1998.tb02590.xen_US
dc.identifier.sourceAcademic Emergency Medicineen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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