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Inositol-requiring 1/X-box-binding protein 1 is a regulatory hub that links endoplasmic reticulum homeostasis with innate immunity and metabolism

dc.contributor.authorKaufman, Randal J.en_US
dc.contributor.authorCao, Siyanen_US
dc.date.accessioned2010-07-06T14:27:24Z
dc.date.available2011-03-01T16:26:45Zen_US
dc.date.issued2010-06en_US
dc.identifier.citationKaufman, Randal J.; Cao, Siyan (2010). "Inositol-requiring 1/X-box-binding protein 1 is a regulatory hub that links endoplasmic reticulum homeostasis with innate immunity and metabolism." EMBO Molecular Medicine 2(6): 189-192. <http://hdl.handle.net/2027.42/77427>en_US
dc.identifier.issn1757-4676en_US
dc.identifier.issn1757-4684en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/77427
dc.description.abstractInositol-requiring 1 (IRE1)/X-box-binding protein 1 (XBP1)-mediated signalling represents the most conserved branch of the unfolded protein response. A series of recent studies reveal novel and potentially ancient roles for this pathway in the coordination of metabolic and immune responses.en_US
dc.format.extent271940 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWILEY-VCH Verlagen_US
dc.subject.otherCell Biologyen_US
dc.subject.otherGeneticsen_US
dc.titleInositol-requiring 1/X-box-binding protein 1 is a regulatory hub that links endoplasmic reticulum homeostasis with innate immunity and metabolismen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, MI, USA ; Howard Hughes Medical Institute, University of Michigan Medical Center, Ann Arbor, MI, USA ; Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA ; Tel: 734-763-9037; Fax: 734-763-9323en_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, MI, USAen_US
dc.identifier.pmid20533428en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/77427/1/189_ftp.pdf
dc.identifier.doi10.1002/emmm.201000076en_US
dc.identifier.sourceEMBO Molecular Medicineen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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