Hypoglossal nerve conduction findings in obstructive sleep apnea
dc.contributor.author | Ramchandren, Sindhu | en_US |
dc.contributor.author | Gruis, Kirsten L. | en_US |
dc.contributor.author | Chervin, Ronald D. | en_US |
dc.contributor.author | Lisabeth, Lynda D. | en_US |
dc.contributor.author | Concannon, Maryann | en_US |
dc.contributor.author | Wolfe, James | en_US |
dc.contributor.author | Albers, James W. | en_US |
dc.contributor.author | Brown, Devin L. | en_US |
dc.date.accessioned | 2010-08-02T17:47:36Z | |
dc.date.available | 2011-03-01T16:26:48Z | en_US |
dc.date.issued | 2010-08 | en_US |
dc.identifier.citation | Ramchandren, Sindhu; Gruis, Kirsten L.; Chervin, Ronald D.; Lisabeth, Lynda D.; Concannon, Maryann; Wolfe, James; Albers, James W.; Brown, Devin L. (2010). "Hypoglossal nerve conduction findings in obstructive sleep apnea." Muscle & Nerve 42(2): 257-261. <http://hdl.handle.net/2027.42/77518> | en_US |
dc.identifier.issn | 0148-639X | en_US |
dc.identifier.issn | 1097-4598 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/77518 | |
dc.description.abstract | Denervation of oropharyngeal muscles in obstructive sleep apnea (OSA) has been suggested by needle electromyography (EMG) and muscle biopsy, but little is known about oropharyngeal nerve conduction abnormalities in OSA. We sought to compare hypoglossal nerve conduction studies in patients with and without OSA. Unilateral hypoglossal nerve conduction studies were performed on 20 subjects with OSA and 20 age-matched controls using standard techniques. Median age was 48 years in OSA subjects and 47 years in controls. Hypoglossal compound muscle action potential (CMAP) amplitudes were significantly reduced ( P = 0.01, Wilcoxon signed-rank test), but prolongation of latencies in OSA subjects did not reach significance in comparison to those of controls. Among a subgroup of subjects without polyneuropathy (15 pairs), reduced amplitudes in OSA subjects retained borderline significance ( P = 0.05). Hypoglossal nerve conduction abnormalities may distinguish patients with OSA from controls. These abnormalities could potentially contribute to, or arise from, OSA. Muscle Nerve, 2010 | en_US |
dc.format.extent | 139807 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Neuroscience, Neurology and Psychiatry | en_US |
dc.title | Hypoglossal nerve conduction findings in obstructive sleep apnea | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Neuromuscular Program and EMG Laboratory, Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Sleep Disorders Center, University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | The Cardiovascular Center, Stroke Program, 1500 East Medical Center Drive, SPC 5855, Ann Arbor, Michigan 48109-5855, USA ; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Neuromuscular Program and EMG Laboratory, Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Neuromuscular Program and EMG Laboratory, Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationother | Department of Neurology, Wayne State University–Detroit Medical Center, Detroit, Michigan, USA | en_US |
dc.contributor.affiliationother | The Cardiovascular Center, Stroke Program, 1500 East Medical Center Drive, SPC 5855, Ann Arbor, Michigan 48109-5855, USA | en_US |
dc.contributor.affiliationother | The Cardiovascular Center, Stroke Program, 1500 East Medical Center Drive, SPC 5855, Ann Arbor, Michigan 48109-5855, USA ; The Cardiovascular Center, Stroke Program, 1500 East Medical Center Drive, SPC 5855, Ann Arbor, Michigan 48109-5855, USA | en_US |
dc.identifier.pmid | 20544939 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/77518/1/21690_ftp.pdf | |
dc.identifier.doi | 10.1002/mus.21690 | en_US |
dc.identifier.source | Muscle & Nerve | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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