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Ultrasound ionization of biomolecules

dc.contributor.authorWu, Chen-Ien_US
dc.contributor.authorWang, Yi-Shengen_US
dc.contributor.authorChen, Nelson G.en_US
dc.contributor.authorWu, Chung-Yien_US
dc.contributor.authorChen, Chung-Hsuanen_US
dc.date.accessioned2010-09-02T15:21:11Z
dc.date.available2011-03-01T16:26:44Zen_US
dc.date.issued2010-09-15en_US
dc.identifier.citationWu, Chen-I; Wang, Yi-Sheng; Chen, Nelson G.; Wu, Chung-Yi; Chen, Chung-Hsuan (2010). "Ultrasound ionization of biomolecules." Rapid Communications in Mass Spectrometry 24(17): 2569-2574. <http://hdl.handle.net/2027.42/77951>en_US
dc.identifier.issn0951-4198en_US
dc.identifier.issn1097-0231en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/77951
dc.description.abstractTo date, mass spectrometric analysis of biomolecules has been primarily performed with either matrix-assisted laser desorption/ionization (MALDI) or electrospray ionization (ESI). In this work, ultrasound produced by a simple piezoelectric device is shown as an alternative method for soft ionization of biomolecules. Precursor ions of proteins, saccharides and fatty acids showed little fragmentation. Cavitation is considered as a primary mechanism for the ionization of biomolecules. Copyright © 2010 John Wiley & Sons, Ltd.en_US
dc.format.extent204923 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherJohn Wiley & Sons, Ltd.en_US
dc.subject.otherChemistryen_US
dc.subject.otherAnalytical Chemistry and Spectroscopyen_US
dc.titleUltrasound ionization of biomoleculesen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USAen_US
dc.contributor.affiliationotherThe Genomics Research Center, Academia Sinica, Taipei, Taiwan, Republic of Chinaen_US
dc.contributor.affiliationotherThe Genomics Research Center, Academia Sinica, Taipei, Taiwan, Republic of Chinaen_US
dc.contributor.affiliationotherThe Genomics Research Center, Academia Sinica, Taipei, Taiwan, Republic of Chinaen_US
dc.contributor.affiliationotherThe Genomics Research Center, Academia Sinica, Taipei, Taiwan, Republic of China ; The Genomics Research Center, Academia Sinica, 128 Academia Road, Sec.2, Nankang, Taipei, Taiwan.en_US
dc.identifier.pmid20740532en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/77951/1/4677_ftp.pdf
dc.identifier.doi10.1002/rcm.4677en_US
dc.identifier.sourceRapid Communications in Mass Spectrometryen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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