Now showing items 61-70 of 477
Role of CFTR in lysosome acidification
(Elsevier, 1992-04-15)
The role of CFTR in lysosome acidification was examined in CFPAC-1 pancreatic adenocarcinoma cells with the [Delta]F508 mutation that were transduced with a retroviral vector (PLJ-CFPAC) or with the normal CFTR gene ...
Gastroduodenal mucosal damage with salsalate versus aspirin: Results of experimental models and endoscopic studies in humans
(Elsevier, 1990-10)
Animal models have identified multiple mechanisms of aspirin toxicity. Aspirin inhibits cyclooxygenase in the gastroduodenal mucosa leading to a decrease in endogenous prostaglandins. Prostaglandin mediated mucus and ...
Overexpression of Human Intestinal Oligopeptide Transporter in Mammalian Cells via Adenoviral Transduction
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1998-09)
Purpose . Our goals are to establish an in vitro screening system and to evaluate a new approach in improving oral absorption of peptides and peptide-like drugs by overexpression of the human intestinal oligo-peptide ...
The Absence of Accessible Vitronectin Receptors in Differentiated Tissue Hinders Adenoviral-Mediated Gene Transfer to the Intestinal Epithelium In Vitro
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1997-09)
Purpose . Adenoviral (Ad) vectors have been used as efficient tools for gene therapy in various tissues, whereas in some differentiated epithelium transduction efficiency is almost abolished.
The human ZBP-89 homolog, located at Chromosome 3q21, represses gastrin gene expression
(Springer-Verlag; Springer-Verlag New York Inc., 1998-02)
TECHNICAL REPORT: Rapid confirmation of gene targeting in embryonic stem cells using two long-range PCR techniques
(Kluwer Academic Publishers; Chapman and Hall ; Springer Science+Business Media, 1998-03)
Gene targeting in mouse embryonic stem (ES) cells generally includes the analysis of numerous colonies to identify a few with mutations resulting from homologous recombination with a targeting vector. Thus, simple and ...
Delayed Gastric Emptying after Laparoscopic Anterior Highly Selective and Posterior Truncal Vagotomy
(Blackwell Publishing Ltd, 1995-05)
Colorimetric method for susceptibility testing of voriconazole and other triazoles against Candida species
(Blackwell Science Ltd, 1999-11)