Now showing items 21-30 of 50
Optimal design of feedback control by inhibition
(Springer-Verlag, 1975-09)
The local stability of unbranched biosynthetic pathways is examined by mathematical analysis and computer simulation using a novel nonlinear formalism that appears to accurately describe biochemical systems. Four factors ...
Metabolic regulation of aminoacyl-tRNA synthetase formation in bacteria
(Elsevier, 1972-10-17)
The cellular levels of several aminoacyl-tRNA synthetases vary with the rate of growth of , and of , in different media. Over a seven-fold range in growth rate the levels of arginyl- and of valyl-tRNA synthetase change ...
Cooperative effects of bacterial mutations affecting [lambda] N gene expression : I. Isolation and characterization of a nusB mutant
(Elsevier, 1976-08)
We report the isolation and characterization of an Escherichia coli mutant which limits the growth of phage [lambda] by inhibiting the expression of the N gene regulatory function. The mutation involved maps near minute ...
Bacteraemia in asymptomatic human subjects
(Elsevier, 1977)
The common occurrence of post-tooth extraction bacteraemia provides a convenient model system to evaluate techniques which demonstrate the magnitude of the bacteraemia. The system used continuous anaerobiosis and membrane ...
Relative effectiveness of methods for immunizing BALB/cwm mice to transplantable myelomonocytic leukemia
(Elsevier, 1979)
An experimental model of transplantable myelomonocytic leukemia (WEHI-3B) was developed in syngeneic BALB/cwm mice to characterize immune mechanisms in this disease. The relative effectiveness of various methods for ...
Plasmid transfer in Streptococcus faecalis: Production of multiple sex pheromones by recipients
(Elsevier, 1979-07)
In a previous report (1978, Proc. Nat. Acad. Sci. USA 75, 3479-3483), we showed that recipient strains of Streptococcus faecalis excrete a heat-stable substance (sex pheromone) which induces donor cells carrying certain ...
Inhibition of growth by imadazol(on)e propionic acid: Evidence in vivo for coordination of histidine catabolism with the catabolism of other amino acids
(Springer-Verlag, 1979-01)
Imidazole propionic acid (ipa), a gratuitous inducer of the histidine-utilization ( hut ) system in Salmonella typhimurium , inhibits the organism's growth on succinate minimal medium. Induction of the hut system is ...
A possible role in the regulation of primary amination for a complex of glutamine: [alpha]-Ketoglutarate amidotransferase and glutamate dehydrogenase in
(Elsevier, 1972-07-11)
Both glutamine: [alpha]-ketoglutarate amidotransferase and glutamate dehydrogenase activities are obtained from grown in minimal medium containing glucose and ammonia. These activities are not additive, suggesting an ...
Interference with the expression of the N gene function of phage [lambda] in a mutant of Escherichia coli
(Elsevier, 1973-01)
An Escherichia coli mutant nus, which inhibits the growth of [lambda] by inhibiting the expression of the [lambda] N gene product, has been further characterized. The N protein regulates phage development by stimulating ...
Genetic characterization of a bacterial locus involved in the activity of the N function of phage [lambda]
(Elsevier, 1974-03)
We report the genetic mapping of a locus of the Escherichia coli chromosome involved in the expression of the N gene function of phage [lambda]. This phage specified function regulates the subsequent transcription of most ...