Now showing items 21-30 of 345
Intratumoral IL-12 and TNF-α–Loaded Microspheres Lead To Regression of Breast Cancer and Systemic Antitumor Immunity
(Springer-Verlag; The Society of Surgical Oncology, Inc., 2004-01)
Background: Local, sustained delivery of cytokines at a tumor can enhance induction of antitumor immunity and may be a feasible neoadjuvant immunotherapy for breast cancer. We evaluated the ability of intratumoral ...
Comparative proteomic study of two closely related ovarian endometrioid adenocarcinoma cell lines using cIEF fractionation and pathway analysis
(WILEY-VCH Verlag, 2009-04)
The proteomic profiles from two distinct ovarian endometrioid tumor-derived cell lines, (MDAH-2774 and TOV-112D) each with different morphological characteristics and genetic mutations, have been studied. Characterization ...
Ultrastructure and cell-cell coupling of cardiac myocytes differentiating in embryonic stem cell cultures
(John Wiley & Sons, Inc., 1997)
Differentiation cultures of embryonic stem (ES) cells can be a useful in vitro system for understanding cardiac myocyte development. However, cell morphometry, sarcomere development, and functional cell-cell junction ...
Supercritical fluid jet expansions of polar aromatic carboxylic acids using simple derivatization with detection by resonant two-photon ionization
(Elsevier, 1988)
In this work simple derivatization is used as a means of enhancing the solubility of polar aromatic carboxylic acids in supercritical CO2 and N2O. The supercritical fluid is then expanded from 200 atm and 40[deg]C through ...
Effects of dimethyl sulfoxide on the globally ischemic heart: Possible general relevance to hypothermic organ preservation
(Elsevier, 1982-02)
Isolated perfused rabbit hearts were made globally ischemic for 2 hr, then reperfused. For 5 min before and after ischemia hearts were perfused with hypothermic (20 or 27 [deg]C), hypoxic, substrate-free cardioplegic ...
Plasma gut hormone levels in 37 patients with pheochromocytomas
(Springer-Verlag; Société Internationale de Chirurgie, 1986-08)
Pheochromocytomas are usually recognized by the effects of overproduction of catecholamines, but there are clinical features that cannot be ascribed to catecholamine excess that may be due to vasoactive peptides. We, ...
Mitochondrial function after global cardiac ischemia and reperfusion: Influences of organelle isolation protocols
(Steinkopff-Verlag; Dr. Dietrich Steinkopff Verlag ; Springer Science+Business Media, 1981-05)
Dog hearts were made globally ischemic for 1 hr at normothermia, at 28°C, or at normothermia after perfusion with a hyperkalemic cardioplegia solution. After 1 hr of reperfusion mitochondria were isolated from each heart ...
Comparative proteomic analysis of low stage and high stage endometrioid ovarian adenocarcinomas
(WILEY-VCH Verlag, 2008-04)
Ovarian cancer, the second most common gynecological malignancy, accounts for 3% of all cancers among women in the United States, and has a high mortality rate, largely because existing therapies for widespread disease are ...
Concurrent cisplatin, paclitaxel, and radiotherapy as preoperative treatment for patients with locoregional esophageal carcinoma
(Wiley Subscription Services, Inc., A Wiley Company, 2003-11-15)
BACKGROUND A Phase II trial was conducted at the University of Michigan to determine the efficacy of a preoperative regimen of concurrent cisplatin, paclitaxel, and radiation for patients with locoregional esophageal ...