Now showing items 21-30 of 83
New trends in the treatment of bone metastasis
(Wiley Subscription Services, Inc., A Wiley Company, 2007-12-01)
Bone metastasis is often the penultimate harbinger of death for many cancer patients. Bone metastases are often associated with fractures and severe pain resulting in decreased quality of life. Accordingly, effective ...
Substitution of D-Trp 32 in NPY Destabilizes the Binding Transition State to the Y1 Receptor Site in SK-N-MC Cell Membranes
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1997-04)
The retention rate of the spin label 3-isothiocyanto methyl-2,2,5,5-tetramethyl-1-pyrrolidinyl oxyl spin label (proxyl) attached to the porcine N-acetyl-NPY peptide and the porcine N-acetyl-D-Trp 32 -NPY peptide at Lys 4 ...
Free-jet spectra and structure of o-, m- and p-dihydroxybenzenes
(Elsevier, 1985-11-15)
Analysis of the free-jet spectra of hydroquinone (para), catechol (ortho) and resorcinol (meta) shows the presence of multiple origins in each molecular spectrum which are interpreted as belonging to separate structural isomers.
Rapid profiling of E. coli proteins up to 500 kDa from whole cell lysates using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
(John Wiley & Sons, Ltd., 1997-11)
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry was used to rapidly detect and profile large proteins from Escherichia coli whole cell lysates in the mass range 25–500 kDa. The bacterial ...
Satellite cell depletion in degenerative skeletal muscle
(Kluwer Academic Publishers; Springer Science+Business Media, 2003-12)
Adult skeletal muscle has the striking ability to repair and regenerate itself after injury. This would not be possible without satellite cells, a subpopulation of cells existing at the margin of the myofiber. Under most ...
Chromatofocusing nonporous reversed-phase high-performance liquid chromatography/electrospray ionization time-of-flight mass spectrometry of proteins from human breast cancer whole cell lysates: a novel two-dimensional liquid chromatography/mass spectrometry method
(John Wiley & Sons, Ltd., 2001-02-28)
A novel two-dimensional two-column liquid chromatography/mass spectrometry (LC/MS) technique is described in this work, where chromatofocusing (CF) has been coupled to nonporous reversed-phase (NPS-RP) HPLC to separate ...
Injectable microparticle–gel system for prolonged and localized lidocaine release. II. in vivo anesthetic effects
(Wiley Subscription Services, Inc., A Wiley Company, 2004-09-01)
Current treatment protocols for postoperative pain are beset by either the short duration of the anesthetic effect or requirement of hospitalization of the patients. We reported herein a novel treatment by applying to the ...
Protein profiles and identification of high performance liquid chromatography isolated proteins of cancer cell lines using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
(John Wiley & Sons, Ltd., 1998-12-30)
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) has been used to rapidly profile the protein content of human cell lysates from MCF-10 cell and variant lines. The method was used ...
Improved resolution in the detection of oligonucleotides up to 60-mers in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry using pulsed–delayed extraction with a simple high voltage transistor switch SPONSOR REFEREE: W.H. Benner, Engineering Division, Berkeley National Laboratory, Building 70A, Room 2255E, 1 Cyclotron Road, Berkeley, CA 94720, USA
(John Wiley & Sons, Ltd., 1997-06-15)
Pulsed–delayed extraction using a simple high voltage transistor switch together with various sample purification approaches were used to enhance the resolution in matrix-assisted laser desorption/ionization time-of-flight ...
The identification of phosphoglycerate kinase-1 and histone H4 autoantibodies in pancreatic cancer patient serum using a natural protein microarray
(WILEY-VCH Verlag, 2009-06)
Protein microarrays have been used to explore whether a humoral response to pancreatic cancer-specific tumor antigens has utility as a biomarker of pancreatic cancer. To determine if such arrays can be used to identify ...