Now showing items 1-7 of 7
A cellular model of oxidant-mediated neuronal injury
(Elsevier, 1993-06-25)
Oxidants derived from the partial reduction of oxygen are thought to play a significant role in neuronal injury. We present here a cellular model of neuronal injury mediated by hydrogen peroxide (H2O2) using the PC 12 rat ...
The identification of phosphoglycerate kinase-1 and histone H4 autoantibodies in pancreatic cancer patient serum using a natural protein microarray
(WILEY-VCH Verlag, 2009-06)
Protein microarrays have been used to explore whether a humoral response to pancreatic cancer-specific tumor antigens has utility as a biomarker of pancreatic cancer. To determine if such arrays can be used to identify ...
Validation of reverse phase protein array for practical screening of potential biomarkers in serum and plasma: Accurate detection of CA19-9 levels in pancreatic cancer
(WILEY-VCH Verlag, 2008-08)
The current study analyzed reverse phase protein arrays (RPPA) as a means to experimentally validate biomarkers in blood samples. One microliter samples of sera ( n 14= 1471), and plasma ( n 14= 1478) were serially diluted ...
Pancreatic cancer stem cells and relevance to cancer treatments
(Wiley Subscription Services, Inc., A Wiley Company, 2009-05-01)
Pancreatic cancer continues to be a malignancy with few therapeutic options. The majority of patients that present for an evaluation have locally advanced or metastatic disease that is incurable by surgical approaches. ...
Intercellular calcium waves in cultured enteric glia from neonatal guinea pig
(Wiley Subscription Services, Inc., A Wiley Company, 2003-05)
Enteric glia are important participants in information processing in the enteric nervous system. However, intercellular signaling mechanisms in enteric glia remain largely unknown. We postulated that intercellular calcium ...
Stimulation of myenteric plexus neurite outgrowth by insulin and insulin-like growth factors I and II
(Elsevier, 1992)
A defined culture medium containing insulin, insulin-like growth factor I (IGF-I) or insulin-like growth II (IGF-II) supported morphological development of myenteric plexus neurons derived from neonatal guinea pigs. Insulin ...
Automated integration of monolith-based protein separation with on-plate digestion for mass spectrometric analysis of esophageal adenocarcinoma human epithelial samples
(WILEY-VCH Verlag, 2006-09)
A unique approach of automating the integration of monolithic capillary HPLC-based protein separation and on-plate digestion for subsequent MALDI-MS analysis has been developed. All liquid-handling procedures were performed ...