Now showing items 1-10 of 37
Structural and mechanical evaluations of a topology optimized titanium interbody fusion cage fabricated by selective laser melting process
(Wiley Subscription Services, Inc., A Wiley Company, 2007-11)
A topology optimized lumbar interbody fusion cage was made of Ti-Al6-V4 alloy by the rapid prototyping process of selective laser melting (SLM) to reproduce designed microstructure features. Radiographic characterizations ...
Peptide transporter 2 (PEPT2) expression in brain protects against 5-aminolevulinic acid neurotoxicity
(Blackwell Publishing Ltd, 2007-12)
Current Status and Future Opportunities for Controlling Acromegaly
(Kluwer Academic Publishers; Springer Science+Business Media, 2002-09)
Growth-hormone (GH) secreting adenomas, including acromegaly, account for approximately one-sixth of all pituitary adenomas and are associated with mortality rates at least twice that of the general population. The ultimate ...
Surgical reversal of prolonged blindness from a metastatic neuroblastoma
(Springer-Verlag, 2005-07)
Reports of tumor-related anterior visual pathway blindness that have resolved after surgical decompression are rare. The longest reported duration of tumor-related blindness completely reversed by optic nerve decompression ...
Management of Intrathecal Catheter-Tip Inflammatory Masses: A Consensus Statement
(Blackwell Science Inc, 2002-12)
In a companion article, we synthesized current clinical and preclinical data to formulate hypotheses about the etiology of drug administration catheter-tip inflammatory masses. In this article, we communicate our recommendations ...
Intramedullary Spinal Tumors of Disordered Embryogenesis
(Kluwer Academic Publishers; Springer Science+Business Media, 2000-05)
Abnormal spinal embryogenesis is quite commonplace. While greater than 90 percent of these errors of embryogenesis leads to occult spinal dysraphism with minimal neurologic or orthopedic sequelae, there is a significant ...
Rapid Re-expansion of a Macroprolactinoma After Early Discontinuation of Bromocriptine
(Kluwer Academic Publishers; Springer Science+Business Media, 2000-11)
Prolactin (PRL)-secreting pituitary adenomas are the most common functioning pituitary tumors. Medical treatment with dopamine agonists is the therapy of choice for macroprolactinomas (≥10 mm). Withdrawal of bromocriptine ...
Pergolide As Primary Therapy for Macroprolactinomas
(Kluwer Academic Publishers; Springer Science+Business Media, 2000-12)
The objective of this study is to determine whether pergolide therapy is an effective modality for the de novo treatment of patients with macroprolactinomas. Twenty-two consecutive patients with macroprolactinomas were ...
Medical Management of Growth Hormone-Secreting Pituitary Adenomas
(Kluwer Academic Publishers; Springer Science+Business Media, 2002-06)
The primary treatment of acromegaly remains transsphenoidal adenomectomy, yet the tissue overgrowth of acromegaly often progresses following surgery, and responds to radiotherapy only after significant delay. Persistently ...
GH Receptor Antagonist: Mechanism of Action and Clinical Utility
(Kluwer Academic Publishers; Springer Science+Business Media, Inc., 2005-01)
This review focuses on the development of GH receptor antagonist as a novel agent for treatment of acromegaly, its mechanism of action and potential areas of use. A brief overview of acromegaly, its diagnosis and existing ...