Now showing items 1-10 of 26
Temporal pattern of C1q deposition after transient focal cerebral ischemia
(Wiley Subscription Services, Inc., A Wiley Company, 2006-04)
Recent studies have focused on elucidating the contribution of individual complement proteins to post-ischemic cellular injury. As the timing of complement activation and deposition after cerebral ischemia is not well ...
More TORC for the gluconeogenic engine
(Wiley Subscription Services, Inc., A Wiley Company, 2006-03)
Hepatic gluconeogenesis plays a key role in the maintenance of glucose homeostasis. The hormone glucagon stimulates this process, whereas insulin and adiponectin are inhibitory. In a recent report, Koo et al identify the ...
Sarcolemma-localized nNOS is required to maintain activity after mild exercise
(Nature Publishing Group, 2008-11-27)
Many neuromuscular conditions are characterized by an exaggerated exercise- induced fatigue response that is disproportionate to activity level. This fatigue is not necessarily correlated with greater central or peripheral ...
Modulation of Cardiac Performance by Motor Protein Gene Transfer
(Blackwell Publishing Inc, 2008-03)
Direct monitoring pressure overload predicts cardiac hypertrophy in mice
(IOP Publishing Ltd, 2007-11-01)
Pressure overload (POL) is a classical model for studying cardiac hypertrophy, but there has been no direct measure of hemodynamics in a conscious ambulatory mouse model of POL. We used abdominal aortic constriction to ...
MyoD and myogenin protein expression in skeletal muscles of senile rats
(Springer-Verlag, 2003-03)
We analyzed the level of protein expression of two myogenic regulatory factors (MRFs), MyoD and myogenin, in senile skeletal muscles and determined the cellular source of their production in young adult (4 months old), old ...
Projections from the trigeminal nuclear complex to the cochlear nuclei: A retrograde and anterograde tracing study in the guinea pig
(Wiley Subscription Services, Inc., A Wiley Company, 2004-12-15)
In addition to input from auditory centers, the cochlear nucleus (CN) receives inputs from nonauditory centers, including the trigeminal sensory complex. The detailed anatomy, however, and the functional implications of ...
Reparative myogenesis in long-term denervated skeletal muscles of adult rats results in a reduction of the satellite cell population
(John Wiley & Sons, Inc., 2001-06-01)
This study, conducted on 25-month denervated rat hindlimb muscles, was directed toward elucidating the basis for the poor regeneration that is observed in long-term denervated muscles. Despite a ∼97.6% loss in mean ...
The identification of phosphoglycerate kinase-1 and histone H4 autoantibodies in pancreatic cancer patient serum using a natural protein microarray
(WILEY-VCH Verlag, 2009-06)
Protein microarrays have been used to explore whether a humoral response to pancreatic cancer-specific tumor antigens has utility as a biomarker of pancreatic cancer. To determine if such arrays can be used to identify ...
Transcriptional coactivator PGC-1a integrates the mammalian clock and energy metabolism
(Nature Publishing Group, 2007-05-24)
The mammalian clock regulates major aspects of energy metabolism, including glucose and lipid homeostasis and mitochondrial oxidative metabolism(1,2). The biochemical basis for coordinated control of the circadian clock ...