Deep Blue: Browsing by Author "Jucker, Mathias"

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AD-causing variants that affect PSEN1 transmembrane domains are associated with faster neurodegeneration and cognitive decline compared to those affecting cytoplasmic domains

Schultz, Stephanie A.; Allegri, Ricardo Francisco; Schultz, Aaron P; Goate, Alison; Levey, Allan I.; Fagan, Anne M.; Hanseeuw, Bernard J; Koeppe, Robert A.; Gordon, Brian A.; Cruchaga, Carlos; Karch, Celeste M.; Chen, Charles D.; Xiong, Chengjie; Jack, Clifford R.; Fitzpatrick, Colleen D; McDade, Eric; Chui, Helena C; Mori, Hiroshi; Lee, Jae-Hong; Noble, James M; Hassenstab, Jason J.; Levin, Johannes; Morris, John C.; Johnson, Keith A.; Liu, Lei; Farlow, Martin R.; Jucker, Mathias; Farrell, Michelle E.; Graff-Radford, Neill R.; Joseph-Mathurin, Nelly; Fox, Nick C; Schofield, Peter R; Martins, Ralph N; Sanchez-Valle, Raquel; Perrin, Richard J.; Berman, Sarah; Salloway, Stephen P.; Shirzadi, Zahra; Rosa-Neto, Pedro; Benzinger, Tammie L.S.; Bateman, Randall J.; Sperling, Reisa A.; Chhatwal, Jasmeer P. (Wiley Periodicals, Inc., 2022-12)

(1.7MB)
AD-causing variants that affect PSEN1 transmembrane domains are associated with faster neurodegeneration and cognitive decline compared to those affecting cytoplasmic domains.

Schultz, Stephanie A.; Allegri, Ricardo Francisco; Schultz, Aaron P.; Goate, Alison; Levey, Allan I.; Fagan, Anne M.; Hanseeuw, Bernard J; Koeppe, Robert A.; Gordon, Brian A.; Cruchaga, Carlos; Karch, Celeste M.; Chen, Charles D.; Xiong, Chengjie; Jack, Clifford R.; Fitzpatrick, Colleen D; McDade, Eric; Chui, Helena C; Mori, Hiroshi; Lee, Jae-Hong; Noble, James M; Hassenstab, Jason J.; Levin, Johannes; Morris, John C.; Johnson, Keith A.; Liu, Lei; Farlow, Martin R.; Jucker, Mathias; Farrell, Michelle E.; Graff-Radford, Neill R.; Joseph-Mathurin, Nelly; Fox, Nick C; Schofield, Peter R; Martins, Ralph N; Sanchez-Valle, Raquel; Perrin, Richard J.; Berman, Sarah; Salloway, Stephen P.; Shirzadi, Zahra; Rosa-Neto, Pedro; Benzinger, Tammie L.S.; Bateman, Randall J.; Sperling, Reisa A.; Chhatwal, Jasmeer P. (Wiley Periodicals, Inc., 2022-12)

(1.3MB)
Biomarker clustering in autosomal dominant Alzheimer’s disease

Luckett, Patrick H.; Chen, Charlie; Gordon, Brian A.; Wisch, Julie; Berman, Sarah B.; Chhatwal, Jasmeer P.; Cruchaga, Carlos; Fagan, Anne M.; Farlow, Martin R.; Fox, Nick C.; Jucker, Mathias; Levin, Johannes; Masters, Colin L.; Mori, Hiroshi; Noble, James M.; Salloway, Stephen; Schofield, Peter R.; Brickman, Adam M.; Brooks, William S.; Cash, David M.; Fulham, Michael J.; Ghetti, Bernardino; Jack, Clifford R.; Vöglein, Jonathan; Klunk, William E.; Koeppe, Robert; Su, Yi; Weiner, Michael; Wang, Qing; Marcus, Daniel; Koudelis, Deborah; Joseph-Mathurin, Nelly; Cash, Lisa; Hornbeck, Russ; Xiong, Chengjie; Perrin, Richard J.; Karch, Celeste M.; Hassenstab, Jason; McDade, Eric; Morris, John C.; Benzinger, Tammie L.S.; Bateman, Randall J.; Ances, Beau M. (Wiley Periodicals, Inc., 2023-01)

(1.4MB) (551.5KB) (930.2KB)
Modeling autosomal dominant Alzheimer’s disease with machine learning

Luckett, Patrick H.; McCullough, Austin; Gordon, Brian A.; Strain, Jeremy; Flores, Shaney; Dincer, Aylin; McCarthy, John; Kuffner, Todd; Stern, Ari; Meeker, Karin L.; Berman, Sarah B.; Chhatwal, Jasmeer P.; Cruchaga, Carlos; Fagan, Anne M.; Farlow, Martin R.; Fox, Nick C.; Jucker, Mathias; Levin, Johannes; Masters, Colin L.; Mori, Hiroshi; Noble, James M.; Salloway, Stephen; Schofield, Peter R.; Brickman, Adam M.; Brooks, William S.; Cash, David M.; Fulham, Michael J.; Ghetti, Bernardino; Jack, Clifford R.; Vöglein, Jonathan; Klunk, William; Koeppe, Robert; Oh, Hwamee; Su, Yi; Weiner, Michael; Wang, Qing; Swisher, Laura; Marcus, Dan; Koudelis, Deborah; Joseph‐mathurin, Nelly; Cash, Lisa; Hornbeck, Russ; Xiong, Chengjie; Perrin, Richard J.; Karch, Celeste M.; Hassenstab, Jason; McDade, Eric; Morris, John C.; Benzinger, Tammie L.S.; Bateman, Randall J.; Ances, Beau M. (MIT PressWiley Periodicals, Inc., 2021-06)

(1.4MB) (1.4MB)
Progressive white matter injury in autosomal dominant Alzheimer’s disease is strongly associated with cerebral microbleeds and neurodegeneration

Shirzadi, Zahra; Schultz, Stephanie A.; Yau, Wai-Ying Wendy; Joseph-Mathurin, Nelly; Kantarci, Kejal; Preboske, Gregory M.; Jack, Clifford R.; Farlow, Martin R.; Fagan, Anne M.; Hassenstab, Jason J.; Jucker, Mathias; Morris, John C.; Xiong, Chengjie; Karch, Celeste M.; Fitzpatrick, Colleen D; Levey, Allan I.; Gordon, Brian A.; Schofield, Peter W.; Salloway, Stephen P.; Perrin, Richard J.; McDade, Eric; Levin, Johannes; Cruchaga, Carlos; Allegri, Ricardo Francisco; Fox, Nick C; Goate, Alison; Graff-Radford, Neill R.; Koeppe, Robert; Noble, James M; Chui, Helena C; Berman, Sarah; Mori, Hiroshi; Sanchez-Valle, Raquel; Lee, Jae-Hong; Rosa-Neto, Pedro; Benzinger, Tammie L.S.; Sohrabi, Hamid R; Martins, Ralph N; Schultz, Aaron P.; Bateman, Randall J.; Johnson, Keith A.; Sperling, Reisa A.; Greenberg, Steven M; Chhatwal, Jasmeer P. (Wiley Periodicals, Inc., 2022-12)

(1.6MB)