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- Creator:
- Wang, Danhao and Mi, Zetian
- Description:
- Wurtzite ferroelectrics possess transformative potential for next-generation microelectronics. A comprehensive understanding of their ferroelectric properties and domain energetics is crucial for tailoring their ferroelectric characteristics and exploiting their functional properties in practical devices. Despite burgeoning interest, the exact configurations, and electronic structures of domain walls in wurtzite ferroelectrics remain elusive. In this work, we elucidate the atomic configurations and electronic properties of electric-field-induced domain walls in ferroelectric ScGaN. By combining transmission electron microscopy and theoretical calculations, a novel charged domain wall with a buckled two-dimensional hexagonal phase is revealed. Density functional theory calculations confirm that such domain wall structures further give rise to unprecedented mid-gap states within the forbidden band. Quantitative analysis unveils a universal charge-compensation mechanism stabilizing antipolar domain walls in ferroelectric materials, wherein the polarization discontinuity at the 180º domain wall is compensated by the unbonded valence electrons. Furthermore, the reconfigurable conductivity of these domain walls is experimentally demonstrated, showcasing their potential for ultra-scaled device applications. Our findings represent a pivotal advancement in understanding the structural and electronic properties of wurtzite ferroelectric domain walls and lay the groundwork for fundamental physics studies and device applications.
- Keyword:
- Charged domain walls, Scanning transmission electron microscopy, and Density functional theory calculations
- Discipline:
- Science
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- Creator:
- Brinkmeier, Michelle L, Wang, Su Qing, Pittman, Hannah, Cheung, Leonard Y, and Prasov, Lev
- Description:
- MYRF is a gene that regulates the development and function of the retinal pigmented epithelium (RPE), which play an important role in maintaining photoreceptor structure and function. Mutations in patients have been implicated in eye size disorders, particularly causing a small, but structurally normal eye. We have utilized a molecular technique, single cell RNA sequencing, to investigate how loss of Myrf specifically in the RPE in a mouse model impacts downstream gene expression at three developmental timepoints and used this information to define the role of Myrf in development. Our work identified key cytoskeletal structural genes specific to the RPE, Ermn and Upk3b, and a gene important for the cell survival, Sox10, as critical targets of Myrf. In addition, we have identified and confirmed that the TGFbeta signaling pathway is dysregulated when Myrf is lost during development. This pathway is particularly relevant in RPE health and eye growth. Our electron microscopy and histologic analyses also confirm a defect in RPE structure and function. We place MYRF within a hierarchy of genes involved in RPE development and introduce novel candidate genes for further study as retinal degeneration and nanophthalmos candidate genes.
- Keyword:
- ERMN, MYRF, Hypopigmentation, TMEM98, SOX10, Retinal Pigment Epithelium (RPE), and Retinal degeneration
- Discipline:
- Science
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- Creator:
- Liao, Jiankan, Deng, Sidi, Huan, Xun, and Cooper, Daniel R.
- Description:
- We apply Bayesian inference to reduce network structure uncertainty on material flow analysis (MFA) and demonstrate the methodology through a case study on U.S. steel flow. In addition, we derive an input/output-based analysis to conduct decision-making based on the uncertainty results from MFA
- Keyword:
- Bayesian inference, Network structure uncertainty, Bayesian model selection, and Input/output analysis
- Citation to related publication:
- Liao, Jiankan, Deng, Sidi, Xun Huan, and Daniel Cooper. "Bayesian Model Selection for Network Discrimination and Risk-informed Decision Making in Material Flow Analysis." arXiv preprint arXiv:2501.05556 (2025).
- Discipline:
- Engineering
-
- Creator:
- University of Michigan Museum of Zoology
- Description:
- Scan of specimen ummz:herps:238369 (NOTOTRITON PICADOI) - Limbs. Raw Dataset includes 1601 TIF images (each 461 x 741 x 1 voxel at 0.01300206 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction. and Scan of specimen ummz:herps:238369 (NOTOTRITON PICADOI) - Limbs. Reconstructed Dataset includes 0.013002 TIF images (each 461 x 741 x 1 voxel at 0.013002 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction.
- Keyword:
- Animalia, Chordata, Amphibia, CAUDATA, PLETHODONTIDAE, NOTOTRITON PICADOI, 1987030882, computed tomography, X-ray, and 3D
- Citation to related publication:
- For more information on the original UMMZ specimen, see: https://www.gbif.org/occurrence/1987030882
- Discipline:
- Science
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- Creator:
- University of Michigan Museum of Zoology
- Description:
- Scan of specimen ummz:herps:194448 (PSEUDOTRITON RUBER) - Limbs. Raw Dataset includes 1601 TIF images (each 372 x 652 x 1 voxel at 0.03100344 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction. and Scan of specimen ummz:herps:194448 (PSEUDOTRITON RUBER) - Limbs. Reconstructed Dataset includes 0.031003 TIF images (each 372 x 652 x 1 voxel at 0.031003 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction.
- Keyword:
- Animalia, Chordata, Amphibia, CAUDATA, PLETHODONTIDAE, PSEUDOTRITON RUBER, 1987126336, computed tomography, X-ray, and 3D
- Citation to related publication:
- For more information on the original UMMZ specimen, see: https://www.gbif.org/occurrence/1987126336
- Discipline:
- Science
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- Creator:
- University of Michigan Museum of Zoology
- Description:
- Scan of specimen ummz:herps:143736 (PSEUDOEURYCEA BELLII) - Limbs. Raw Dataset includes 1601 TIF images (each 642 x 2000 x 1 voxel at 0.02199678 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction., Scan of specimen ummz:herps:143736 (PSEUDOEURYCEA BELLII) - Limbs. Reconstructed Dataset includes 0.021997 TIF images (each 642 x 2000 x 1 voxel at 0.021997 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction., and Scan of specimen ummz:herps:143736 (PSEUDOEURYCEA BELLII) - Limbs. Reconstructed Dataset includes 0.021997 TIF images (each 642 x 2000 x 1 voxel at 0.021997 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction.
- Keyword:
- Animalia, Chordata, Amphibia, CAUDATA, PLETHODONTIDAE, PSEUDOEURYCEA BELLII, 1987206748, computed tomography, X-ray, and 3D
- Citation to related publication:
- For more information on the original UMMZ specimen, see: https://www.gbif.org/occurrence/1987206748
- Discipline:
- Science
-
- Creator:
- University of Michigan Museum of Zoology
- Description:
- Scan of specimen ummz:herps:137395 (OEDIPINA POELZI) - Limbs. Raw Dataset includes 1601 TIF images (each 514 x 670 x 1 voxel at 0.02500204 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction. and Scan of specimen ummz:herps:137395 (OEDIPINA POELZI) - Limbs. Reconstructed Dataset includes 0.025002 TIF images (each 514 x 670 x 1 voxel at 0.025002 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction.
- Keyword:
- Animalia, Chordata, Amphibia, CAUDATA, PLETHODONTIDAE, OEDIPINA POELZI, 1987178002, computed tomography, X-ray, and 3D
- Citation to related publication:
- For more information on the original UMMZ specimen, see: https://www.gbif.org/occurrence/1987178002
- Discipline:
- Science
-
- Creator:
- University of Michigan Museum of Zoology
- Description:
- Scan of specimen ummz:herps:126557A (STEREOCHILUS MARGINATUS) - Limbs. Raw Dataset includes 1601 TIF images (each 322 x 588 x 1 voxel at 0.01900397 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction. and Scan of specimen ummz:herps:126557A (STEREOCHILUS MARGINATUS) - Limbs. Reconstructed Dataset includes 0.019004 TIF images (each 322 x 588 x 1 voxel at 0.019004 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction.
- Keyword:
- Animalia, Chordata, Amphibia, CAUDATA, PLETHODONTIDAE, STEREOCHILUS MARGINATUS, 1987059875, computed tomography, X-ray, and 3D
- Citation to related publication:
- For more information on the original UMMZ specimen, see: https://www.gbif.org/occurrence/1987059875
- Discipline:
- Science
-
- Creator:
- University of Michigan Museum of Zoology
- Description:
- Scan of specimen ummz:herps:119705 (THORIUS MACDOUGALLI) - Limbs. Raw Dataset includes 1601 TIF images (each 499 x 1109 x 1 voxel at 0.00900072 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction. and Scan of specimen ummz:herps:119705 (THORIUS MACDOUGALLI) - Limbs. Reconstructed Dataset includes 0.009001 TIF images (each 499 x 1109 x 1 voxel at 0.009001 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction.
- Keyword:
- Animalia, Chordata, Amphibia, CAUDATA, PLETHODONTIDAE, THORIUS MACDOUGALLI, 1987144849, computed tomography, X-ray, and 3D
- Citation to related publication:
- For more information on the original UMMZ specimen, see: https://www.gbif.org/occurrence/1987144849
- Discipline:
- Science
-
- Creator:
- University of Michigan Museum of Zoology
- Description:
- Scan of specimen ummz:herps:119705 (THORIUS MACDOUGALLI) - Limbs. Raw Dataset includes 3141 TIF images (each 658 x 1194 x 1 voxel at 0.00700461 mm resolution, derived from 3141 scan projections), xtek and vgi files for volume reconstruction. and Scan of specimen ummz:herps:119705 (THORIUS MACDOUGALLI) - Limbs. Reconstructed Dataset includes 0.007005 TIF images (each 658 x 1194 x 1 voxel at 0.007005 mm resolution, derived from 3141 scan projections), xtek and vgi files for volume reconstruction.
- Keyword:
- Animalia, Chordata, Amphibia, CAUDATA, PLETHODONTIDAE, THORIUS MACDOUGALLI, 1987144849, computed tomography, X-ray, and 3D
- Citation to related publication:
- For more information on the original UMMZ specimen, see: https://www.gbif.org/occurrence/1987144849
- Discipline:
- Science