Targeted metabolomics analysis of primary WT murine bone marrow-derived macrophages (BMDM) mock-treated or infected with methicillin-resistant Staphylococcus aureus (MRSA) (File S1). Targeted metabolomics analysis of mock-treated or MRSA-infected WT or Ifnar1-/- iBMDM (File S2).
Type I interferon governs immunometabolic checkpoints that coordinate inflammation during Staphylococcal infection Mack B. Reynolds, Benjamin Klein, Michael J. McFadden, Norah K. Judge, Hannah E. Navarrete, Britton C Michmerhuizen, Dominik Awad, Tracey L. Schultz, Paul W. Harms, Li Zhang, Teresa R. O’Meara, Jonathan Z. Sexton, Costas A. Lyssiotis, J. Michelle Kahlenberg, Mary X. O’Riordan bioRxiv 2024.01.10.575104; doi: https://doi.org/10.1101/2024.01.10.575104 and Reynolds et al., Type I Interferon governs immunometabolic checkpoints that coordinate inflammation during Staphylococcal infection, Cell Reports (2024), https://doi.org/10.1016/j.celrep.2024.114607
Scan of specimen ummz:mammals:100776 (Erignathus barbatus barbatus) - Skull. Raw Dataset includes 1601 TIF images (each 1385 x 1900 x 1 voxel at 0.09676982 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction. and Scan of specimen ummz:mammals:100776 (Erignathus barbatus barbatus) - Skull. Reconstructed Dataset includes 1440 TIF images (each 1385 x 1900 x 1 voxel at 0.096770 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction.
Scan of specimen ummz:mammals:103505 (Erignathus barbatus NAUTICA) - Skull. Raw Dataset includes 1601 TIF images (each 1346 x 1927 x 1 voxel at 0.1103895 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction. and Scan of specimen ummz:mammals:103505 (Erignathus barbatus NAUTICA) - Skull. Reconstructed Dataset includes 1497 TIF images (each 1346 x 1927 x 1 voxel at 0.110390 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction.
Scan of specimen ummz:mammals:123394 (Potos flavus) - WholeBody. Raw Dataset includes 1601 TIF images (each 1237 x 1177 x 1 voxel at 0.04900547 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction. and Scan of specimen ummz:mammals:123394 (Potos flavus) - WholeBody. Reconstructed Dataset includes 1941 TIF images (each 1237 x 1177 x 1 voxel at 0.049005 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction.
Scan of specimen ummz:mammals:157859 (Uncia uncia) - Skull. Raw Dataset includes 1601 TIF images (each 1400 x 1858 x 1 voxel at 0.1052879 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction. and Scan of specimen ummz:mammals:157859 (Uncia uncia) - Skull. Reconstructed Dataset includes 1367 TIF images (each 1400 x 1858 x 1 voxel at 0.105288 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction.
Scan of specimen ummz:mammals:161319 (Prionailurus bengalensis chinensis) - Skull. Raw Dataset includes 1601 TIF images (each 1259 x 1245 x 1 voxel at 0.04473831 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction. and Scan of specimen ummz:mammals:161319 (Prionailurus bengalensis chinensis) - Skull. Reconstructed Dataset includes 1932 TIF images (each 1259 x 1245 x 1 voxel at 0.044738 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction.
Scan of specimen ummz:mammals:177443 (Phoca vitulina) - Skull. Raw Dataset includes 1601 TIF images (each 1921 x 1443 x 1 voxel at 0.09976429 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction. and Scan of specimen ummz:mammals:177443 (Phoca vitulina) - Skull. Reconstructed Dataset includes 1701 TIF images (each 1921 x 1443 x 1 voxel at 0.099764 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction.
Scan of specimen ummz:mammals:178190 (Leptailurus serval) - Skull. Raw Dataset includes 1601 TIF images (each 1881 x 1287 x 1 voxel at 0.06803631 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction. and Scan of specimen ummz:mammals:178190 (Leptailurus serval) - Skull. Reconstructed Dataset includes 1003 TIF images (each 1881 x 1287 x 1 voxel at 0.068036 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction.
Scan of specimen ummz:mammals:95748 (Hyaena brunnea) - Skull. Raw Dataset includes 1601 TIF images (each 1427 x 1939 x 1 voxel at 0.117297 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction. and Scan of specimen ummz:mammals:95748 (Hyaena brunnea) - Skull. Reconstructed Dataset includes 1662 TIF images (each 1427 x 1939 x 1 voxel at 0.117297 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction.
MCF10A non-tumorigenic breast cells were dosed with environmental toxicants and stained with multiple cellular stains to study morphological perturbations. Following up on feature results, MCF10A cells were stained with an anti-beta catenin antibody to study beta catenin nuclear translocation. Cell profiler software was used to measure and export per cell data .CSV formats to be further analyze din BMDExpress2 and R studio
