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- Creator:
- Kim, Yongsung, Cheng, Weiqiu, Cho, Chun-Seok, Kang, Hyun Min, and Lee, Jun Hee
- Description:
- This dataset contains a typical example of Seq-Scope dataset that investigators would generate after examining the initial sequence data. If the quality of the initial Seq-Scope dataset looks great, one may decide to sequence the library much more deeply to maximize the information content. (see NovaScope tutorial at https://seqscope.github.io/NovaScope/ for more details). The spatial barcode sequences and the initial version of the sequenced cDNA library are deposited separate repository, which is described in the NovaScope documentation ( https://seqscope.github.io/NovaScope/). This data repository contains a deeper sequencing of the same library. A shallower version of sequencing, which does not have overlapping data with the current repository can be found at https://doi.org/10.5281/zenodo.10840695
- Keyword:
- Seq-Scope, Spatial Transcriptomics
- Citation to related publication:
- Yongsung Kim, Weiqiu Cheng, Chun-Seok Cho, Yongha Hwang, Yichen Si, Anna Park, Mitchell Schrank, Jer-En Hsu, Jingyue Xi, Myungjin Kim, Ellen Pedersen, Olivia I. Koues, Thomas Wilson, Goo Jun, Hyun Min Kang2, Jun Hee Lee, “Seq-Scope Protocol: Repurposing Illumina Sequencing Flow Cells for High-Resolution Spatial Transcriptomics” (submitted)
- Discipline:
- Science
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- Creator:
- Alvarado, Roman, Scheven, Ulrich M., and Meiners, Jens-Christian
- Description:
- MRI raw data Image analysis script Raw pressure and vitals data
- Keyword:
- Decompression Sickness
- Citation to related publication:
- Alvarado R, Scheven U. M, Meiners, J. C.: Real-time Imaging of Decompression Gas Bubble Growth in the Spinal Cord of Live Rats, Magnetic Resonance in Medicine, 2024, in press
- Discipline:
- Health Sciences
-
- Creator:
- Lehman, John T
- Description:
- The research was directed at the trophic dynamics, food web structure, and secondary production of lower food web members of the Great Lakes ecosystem. It documented species invasion of the upper Great Lakes by the Eurasian invertebrate predator Bythotrephes, commonly called the spiny water flea.
- Keyword:
- Invasive Species, Limnology, Trophic Dynamics, Zooplankton, Water Chemistry, Secondary Production, Lake Erie, Lake Huron, Lake Michigan, and Lake Superior
- Citation to related publication:
- Burgess, S., E.W. Jackson, L. Schwarzman, N. Gezon, and J.T. Lehman. 2015. Improved estimates of calanoid copepod biomass in the St. Lawrence Great Lakes. Journal of Great Lakes Research 41: 484-491., Doubek, J.P. and J.T. Lehman. 2014. Historical trophic position of Limnocalanus macrurus in Lake Michigan. Journal of Great Lakes Research 40: 1027-1032., Jackson, E.W., J.P. Doubek, J.S. Schaeffer, and J.T. Lehman. 2013. Historical and Recent Biomass and Food Web Relations of Limnocalanus in Lake Huron. Journal of Great Lakes Research 39: 404-408., Doubek, J. P. and J.T. Lehman. 2011. Historical biomass of Limnocalanus in Lake Michigan. Journal of Great Lakes Research 37: 159-164., Sullivan, C. and J.T. Lehman. 1998. Character variation and evidence for spine length selection in the invertebrate predator Bythotrephes (Crustacea: Cladocera) from Lakes Michigan, Huron, and Erie. Arch. Hydrobiol. 142: 35-52., Bilkovic, D.M. and J.T. Lehman. 1997. Lipid content and size variation of Bythotrephes (Cladocera: Cercopagidae) from Lakes Erie, Huron and Michigan. J. Great Lakes Research 23: 149-159., Lehman, J.T., D.M. Bilkovic, and C. Sullivan. 1997. Predicting development, metabolism, and secondary production for the invertebrate predator Bythotrephes. Freshwater Biology 38:343-352., Lehman, J.T. and D.A. Lehman. 1996. Status of the non-indigenous invertebrate predator Bythotrephes cederstroemi (Crustacea: Cladocera) in Lakes Erie, Huron, and Michigan. Proc. Symp. on non-indigenous species in Western Aquatic Ecosystems. Portland State Univ. Lakes and Reservoirs Program Publication No. 96-8: 7-14. , Branstrator, D.K. and J.T. Lehman. 1996. Evidence for juvenile fish predation on Bythotrephes cederstroemi in Lake Michigan. J. Great Lakes Research 22: 917-924., Lehman, J.T. and D.K. Branstrator 1996. Predicting assimilation and development rates of invertebrate predators. J. Great Lakes Research 22: 930-934., Lehman, J.T. and D.K. Branstrator. 1995. A model for growth, development, bioenergetics and diet selection by the invertebrate predator Bythotrephes cederstroemi. J. Great Lakes Research 21: 610-619., Burkhardt, S. and J.T. Lehman. 1994. Prey consumption and predatory effects of an invertebrate predator (Bythotrephes: Cladocera, Cercopagidae) based on phosphorus budgets. Limnol. Oceanogr. 39: 1007-1019., Lehman, J.T. and C. Caceres. 1993. Food web responses to species invasion by a predatory invertebrate: Bythotrephes in Lake Michigan. Limnology and Oceanography 37: 879-891., Branstrator, D.K. and J.T. Lehman. 1991. Invertebrate predation in Lake Michigan: Regulation of Bosmina longirostris by Leptodora kindti. Limnology and Oceanography 36: 483-495., Lehman, J.T. 1991. Causes and consequences of cladoceran dynamics in Lake Michigan: Implications of species invasion by Bythotrephes. Journal of Great Lakes Research 17: 437-445., Lehman, J.T., J.A. Bowers, R.W. Gensemer, G.J. Warren, and D.K. Branstrator. 1990. Mysis relicta in Lake Michigan: Abundances and relationships with their potential prey, Daphnia. Canadian J. Fisheries and Aquatic Sciences 47: 977-983., Lehman, J.T. and C.D. Sandgren. 1990. Trophic dynamics of Lake Michigan: Response of algal production to changes in the zooplankton community. Verh. Internat. Verein. Limnol. 24: 397-400., Sandgren, C.D. and J.T. Lehman. 1990. Response of chlorophyll a, phytoplankton, and microzooplankton to the invasion of Lake Michigan by Bythotrephes. Verh. Internat. Verein. Limnol. 24: 386-392., Lehman, J.T. 1988. Algal biomass unaltered by food web changes in Lake Michigan. Nature 332: 537-538., Warren, G.J. and J.T. Lehman. 1988. Young-of-the-year Coregonus hoyi in Lake Michigan: Prey selection and influence on the zooplankton community. Journal of Great Lakes Research 14: 420-426., Dorazio, R.M., J.A. Bowers, and J.T. Lehman. 1987. Food-web manipulations influence grazer control of phytoplankton growth rates in Lake Michigan. Journal of Plankton Research 9: 891-899., and Lehman, J.T. 1987. Palearctic predator invades North American Great Lakes. Oecologia 74: 478-480.
- Discipline:
- Science
-
- Creator:
- Su, Xue and Zhang, Youxue
- Description:
- The H2O concentration and H2O/Ce ratio in olivine-hosted melt inclusions are high (H2O up to 1410 ppm; H2O/Ce up to 77) in lunar sample 74220 but lower (H2O up to 430 ppm; H2O/Ce up to 9.4) in all other lunar samples studied before this work. This difference is absent for other volatiles (F, S, and Cl) in melt inclusions in 74220 and other lunar samples. Because H2O (or H) is a critical volatile component with significant ramifications on the origin and evolution of the Moon, it is important to understand what causes such a large gap in H2O/Ce ratio between 74220 and other lunar samples. Two explanations have been advanced. One is that volcanic product in sample 74220 has the highest cooling rate and thus best preserved H2O in melt inclusions compared to melt inclusions in other samples. The other explanation is that sample 74220 is a localized heterogeneity enriched in some volatiles. To distinguish the two possibilities, here we present new data from three rapidly cooled lunar samples: olivine-hosted glassy melt inclusions (OHMIs) in 74220 regolith and 79135 regolith breccia, and pyroxene-hosted glassy melt inclusions (PHMIs) in 15597 pigeonite basalts. If the gap is due to the difference in cooling rates, samples with cooling rates between 74220 and other studied lunar samples should have preserved intermediate H2O concentrations and H2O/Ce ratios. Our results show that melt inclusions in 79135 and 15597 contain high H2O concentrations (up to 969 ppm in 79135 and up to 793 ppm in 15597) and high H2O/Ce ratios (up to 21 in 79135 and up to 13 in 15997). Combined with literature data, we confirm that H2O/Ce ratios of different lunar samples are positively correlated to the cooling rates and independent of the type of mare basalts. Our work bridges the big gap in H2O/Ce ratio among 74220 and other lunar samples. We hence reinforce the interpretation that the lunar sample with the highest cooling rate best represents pre-eruptive volatiles in lunar basalts due to the least degassing. H2O, F, P, S and Cl concentrations in the lunar primitive mantle are also estimated in this work. and *** 2024-03-19: In addition to the files in the previous version, this updated deposit contains more data files as the supplementary files of the paper. For example, we added a summary excel file containing data that are used for figures in the paper, and an excel file contains data in the tables of the paper for easy use by readers. See ReadMe.txt for changes.
- Keyword:
- Water in the Moon, volatiles in the Moon, olivine-hosted melt inclusions, pyroxene-hosted melt inclusions, F/P ratio, S/Dy ratio, Cl/Ba ratio
- Discipline:
- Science
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Division of Birds
User Collection- Creator:
- University of Michigan Museum of Zoology
- Description:
- University of Michigan Museum of Zoology Division of Birds
- Discipline:
- Science
1Works -
Division of Fishes
User Collection- Creator:
- University of Michigan Museum of Zoology
- Description:
- Division of Fishes
- Discipline:
- Science
48Works -
Division of Reptiles and Amphibians
User Collection- Creator:
- University of Michigan Museum of Zoology
- Description:
- The Division of Reptiles and Amphibians maintains a collection that is worldwide in scope. The research collections contain over 200,000 catalogued lots representing approximately 435,000 individual specimens.
- Discipline:
- Science
13Works -
Division of Mammals
User Collection- Creator:
- University of Michigan Museum of Zoology
- Description:
- The Division of Mammals at the Museum of Zoology was established in 1837, and has grown steadily to its current size, with over 150,000 specimens. An important feature of the mammal collection at the Museum of Zoology is our emphasis on non-traditional specimens.
- Discipline:
- Science
22Works -
University of Michigan Museum of Zoology
User Collection- Creator:
- University of Michigan Museum of Zoology
- Description:
- The University of Michigan Museum of Zoology (UMMZ) is the center for the study of animal diversity on campus, focusing on the evolutionary origins of the planet’s animal species, the genetic information they contain and the communities and ecosystems they help form. Now an integral part of the Department of Ecology and Evolutionary Biology (EEB), the UMMZ houses world-class collections, containing more than 15 million specimens, span almost 200 years of regional and global biodiversity studies and that support a multi-faceted Departmental research and teaching program.
- Discipline:
- Science
4Sub-collections0Works -
- Creator:
- Irani, Sanaya , Tolia, Sangini, Finks, Jonathan, and Sandhu, Gurjit
- Description:
- Program Description DoT was founded in 2012 with a mission to increase diversity amongst medical professionals by preparing students from underrepresented communities in Detroit to successfully pursue careers in healthcare. Our program builds on a partnership between Cass Technical High School (CTHS) and the University of Michigan Medical School (UMMS). The CTHS student body is reflective of the Detroit population with more than 80% of students identifying with racial and ethnic minority backgrounds. Students with an interest in healthcare apply for the program as ninth graders. In recent years, the program has received over 60 applications for approximately 30 positions in each grade. DoT’s unique strength lies in its longitudinal structure. There are three branches of the program – Foundations (ninth and tenth grade), Rising (eleventh and twelfth grade) and Succeed (undergraduate). Ninth graders start out in DoT Foundations. Each student is paired with a first-year medical student mentor at UMMS for the entire academic year. DoT students travel to UMMS every month for a visit day, with activities designed to give students hands-on experiences in healthcare, such as suturing and ultrasound skills in the simulation center, and clinical shadowing. Students then meet with their medical student mentor over lunch. The latter part of the day is dedicated to working on their capstone projects. For the capstone projects, students work in small teams led by medical student leaders to identify a community health issue, partner with a local organization, and present their proposed solutions at a formal symposium at the end of the year. , Transition to Virtual Programming In light of the recent COVID-19 pandemic, a growing number of universities cancelled all campus events including those of pipeline programs. We felt that our programming offered an important service to our students that would be greatly missed, so our team worked to quickly create and implement a virtual program. We ensured that each of our students had access to technology at home and those who did not were offered scholarships. During our introductory student session and new parent meeting, our leadership team discussed how to set up a Gmail email address for weekly communications and taught the students how to use Zoom, Google Drive, Google Docs and Google Sheets for online learning collaboration. For the virtual Foundations program, we offered 1-hour seminars each month, where a physician was invited to give a 30-minute presentation about different organ systems, followed by a 30-minute case-based session where students worked with medical student mentors to apply their new knowledge. We also created novel sessions such as “The Path to College and Medical School” and collaborated with members of the Black Medical Association (BMA) and Latin American and Native American Medical Association (LANAMA) to host a panel session where students could learn from medical students who identified as URiM. For the mentorship aspect, we created “pods” of Foundations, Rising, and Succeed students along with medical student and physician mentors. The Foundations students and mentors met every month for an hour on Zoom, a virtual communication platform, to work on their Capstone project. Rising and Succeed students joined the group for three full-pod meetings. The goal was to increase near-peer mentorship and connections between DoT students at all levels. , and Study Population Due to the virtual nature of the 2020-2021 program, we accepted 100% of 9th grade applicants from CTHS. We also expanded our reach to a new school, The School at Marygrove (TSM), which is also located in Detroit, Michigan. TSM is involved in the Detroit-20 Partnership with the University of Michigan College of Education and includes a novel three-year residency program for novice teachers. During the 2020-2021 school year, 108 students participated in the Foundations programming with 72 of them being 9th graders and 36 being 10th graders. The students were mostly from CTHS with 12 students out of the 108 total being from TSM. Students were predominantly from an African American/Black racial background (68.4% from N=98 respondents). The students were representative of their respective schools. The majority of students at CTHS identify as black, come from low-income homes, and have variable levels of parental education.
- Keyword:
- pipeline program, Underrepresented in medicine, Mentorship, Medical education, and COVID-19
- Discipline:
- Health Sciences