Search Constraints
Number of results to display per page
View results as:
Search Results
-
- Creator:
- Dumlao, James M. Zumel and Teplitskiy, Misha
- Description:
- The data sources and methods used to process the raw data are described in the paper forthcoming in Science and the associated Supplementary Information. A preprint for an earlier version of this paper is available here: https://osf.io/preprints/socarxiv/754e3. These data are anonymized (see Methodology for details). Consequently, running the same code on these data vs. the data in the paper does not yield *identical* results but qualitatively similar ones.
- Keyword:
- peer review, double-anonymization, geographic diversity, homophily, fairness, and bias
- Citation to related publication:
- J. M. Z. Dumlao, M. Teplitskiy, Science, forthcoming. and Zumel Dumlao, J. M. and M. Teplitskiy. 2023. “The Effect of Reviewer Geographical Diversity on Evaluations Is Reduced by Anonymizing Submissions”. Retrieved (osf.io/preprints/socarxiv/754e3).
- Discipline:
- Science and Social Sciences
-
Neuronal splicing of the unmethylated histone H3K4 reader, PHF21A, prevents excessive synaptogenesis
- Creator:
- Nagai, Masayoshi, Porter, Robert S., Miyasato, Maxwell, Wang, Aijia, Gavilan, Cecilia M., Hughes, Elizabeth D., Wu, Michael C., Saunders, Thomas L., and Iwase, Shigeki
- Description:
- LSD1 histone H3K4 demethylase and its binding partner PHF21A, a reader protein for unmethylated H3K4, both undergo neuron-specific microexon splicing. The LSD1 neuronal microexon weakens H3K4 demethylation activity and can alter the substrate specificity to H3K9 or H4K20. Meanwhile, the PHF21A neuronal microexon interferes with nucleosome binding. However, the temporal expression patterns of LSD1 and PHF21A splicing isoforms during brain development remain unknown. In this work, we report that neuronal PHF21A isoform expression precedes neuronal LSD1 isoform expression during human neuron differentiation and mouse brain development. The asynchronous splicing events resulted in stepwise deactivation of the LSD1-PHF21A complex in reversing H3K4 methylation. We further show that the enzymatically inactive LSD1-PHF21A complex interacts with neuron-specific binding partners, including MYT1-family transcription factors and post-transcriptional mRNA processing proteins such as VIRMA. The interaction with the neuron-specific components, however, did not require the PHF21A microexon, indicating that the neuronal proteomic milieu, rather than the microexon-encoded PHF21A segment, is responsible for neuron-specific complex formation. These results indicate that the PHF21A microexon is dispensable for neuron-specific protein-protein interactions, yet the enzymatically inactive LSD1-PHF21A complex might have unique gene-regulatory roles in neurons.
- Citation to related publication:
- Nagai, M., Porter, R. S., Miyasato, M., Wang, A., Gavilan, C. M., Hughes, E. D., Wu, M. C., Saunders, T. L., Iwase, S. Neuronal splicing of the unmethylated histone H3K4 reader, PHF21A, prevents excessive synaptogenesis. Journal of Biological Chemistry (2024).
- Discipline:
- Science
-
- Creator:
- Pedde, Meredith
- Description:
- In this study, we took advantage of the randomized allocation of the US EPA's funding for school bus replacements and retrofits to causally assess the impacts of upgrading buses on student attendance through the EPA’s national School Bus Rebate Program. Specifically, we used classical intent-to-treat analyses for randomized controlled trials to compare the change in school district level attendance rates after vs before the 2012 through 2017 lotteries by funding selection status . We used overall district attendance rates since rates were not available for only school-bus riders.
- Keyword:
- School Bus Emissions, Diesel Air Pollution, and School Attendance
- Citation to related publication:
- Pedde, M., Szpiro, A., Hirth, R. et al. Randomized design evidence of the attendance benefits of the EPA School Bus Rebate Program. Nat Sustain (2023). https://doi.org/10.1038/s41893-023-01088-7
- Discipline:
- Health Sciences
-
- Creator:
- Pedde, Meredith
- Description:
- In this study, we took advantage of the randomized allocation of the US EPA's funding for school bus replacements and retrofits to causally assess the impacts of upgrading buses on students' educational performance through the EPA’s national School Bus Rebate Program. Specifically, we used classical intent-to-treat analyses for randomized controlled trials to compare the change in school district level reading and language arts and math standardized test scores after vs before the 2012 through 2016 lotteries by funding selection status . We used overall district average standardized test scores since rates were not available for only school-bus riders.
- Keyword:
- School Bus Emissions, Diesel Air Pollution, and Student standardized testing
- Citation to related publication:
- Pedde, M., Szpiro, A., Hirth, R., Adar, S. School Bus Rebate Program and Student Educational Performance Test Scores. JAMA Network Open (2024). https://doi.org/10.1001/jamanetworkopen.2024.3121
- Discipline:
- Health Sciences
-
- Creator:
- A. Abeid, Bachir , L. Fabiilli, Mario , Aliabouzar, Mitra, and Estrada, Jon B.
- Description:
- Images of droplet dynamics during and after optical excitation experiments were recorded in the ultra-fast regime at 1 million frames per second (fps) while the low-speed, quasi-static evolution was carried at 1 fps. During both the inertial and quasi-static phases, we record 1–3 frames in the reference configuration prior to the arrival of the laser-pulse to distinguish the bubble from the background. Lastly, due to the complex physics of plasma formation and chemistry, forward simulations begin at the time when the bubble reaches its maximum expansion
- Keyword:
- optical droplet vaporization, cavitation, viscoelasticity, ultra-high-speed imaging, hydrogel, numerical modeling.
- Citation to related publication:
- Abeid, Bachir A, et al. (2024). Experimental and numerical investigations of ultra-high-speed dynamics of optically induced droplet cavitation in soft materials
- Discipline:
- Science and Engineering
-
- Creator:
- Hawes, Jason K
- Description:
- Most of this deposit is composed of a step-by-step explanation of how to replicate the work conducted in Chapters 2 and 5 of my dissertation (available in DeepBlue Documents under the title Urban Agriculture: Good for People, Places, and Planet?). Very little actual data is catalogued here, instead largely relying on links to the secondary datasets online. In fact, this is an intentional choice, since any replication would likely want updated data to produce more real-time results. This deposit is intended to accompany the dissertation and may not be the final version of these two manuscripts or their associated methods. For more up-to-date methods and analysis, please search Google Scholar or your affiliated library for Jason Hawes and some combination of keywords including urban agriculture, scaling-up, tradeoffs, or the names of the cities in question.
- Keyword:
- urban agriculture, tradeoffs, remote sensing, and multi-criteria analysis
- Discipline:
- Social Sciences
-
- Creator:
- Wu, Wenbing, Kadar, Alain, Lee, Sang Hyun, Jung, Hong Ju, Park, Bum Chul, Raymond, Jeffery, Tsotsis, Thomas, Cesnik, Carlos, Glotzer, Sharon, Goss, Valerie, and Kotov, Nicholas
- Description:
- The goal of this project is to relate properties of nanowire networks to their structure. The structure of these networks was determined from electron and atomic force microscopy, which were used as the basis for property predictions. Properties include sheet resistance, conductive anisotropy, absorption spectra, and current capacity.
- Keyword:
- structural complexity, nanowires, graph theory (GT), complex particle systems, complex composites, correlated disorder
- Citation to related publication:
- Preprint: https://arxiv.org/pdf/2310.15369
- Discipline:
- Engineering
-
- Creator:
- El Shair, Zaid A., Abu-raddaha, Abdalmalek , Cofield, Aaron, Alawneh, Hisham, Aladem, Mohamed, Hamzeh, Yazan, and Rawashdeh, Samir A.
- Description:
- The SID dataset was curated to support advanced research in autonomous driving systems, particularly focusing on perception under adverse weather and lighting conditions. This dataset encompasses over 178k high-resolution stereo image pairs organized into 27 sequences, reflecting a rich variety of conditions such as snow, rain, fog, and low light. It covers dynamic changes in driving scenarios and environmental backgrounds, including university campuses, residential streets, and urban settings. The dataset is designed to challenge perception algorithms with scenarios such as partially obscured camera lenses and varying visibility, promoting the development of robust computer vision models. No specialized software or scripts are necessary for accessing the image data, as the files are provided in standard PNG format. However, researchers and developers may require their image processing and computer vision toolkits to utilize the dataset effectively in their work.
- Keyword:
- Autonomous Driving, Adverse Weather, Stereo Vision, Image Dataset, Computer Vision, and Perception Algorithms
- Citation to related publication:
- El-Shair, Z.A., Abu-raddaha, A., Cofield, A., Alawneh, H., Aladem, M., Hamzeh, Y. and Rawashdeh, S.A., 2024, July. SID: Stereo Image Dataset for Autonomous Driving in Adverse Conditions. In NAECON 2024-IEEE National Aerospace and Electronics Conference (pp. 403-408). IEEE.
- Discipline:
- Engineering
-
- Creator:
- Ye, Zhengwei and Mi, Zetian
- Description:
- Generation of C2+ compounds using sunlight, carbon dioxide, and water provides a promising path for carbon neutrality. The exploration of a catalyst to break the bottleneck of C-C coupling, for constructing a rational artificial photosynthesis integrated device, is at the core. Herein, based on operando spectroscopy measurements, theoretical calculations, and feedstock experiments, it is discovered that gold, in conjunction with iridium, can catalyze the reduction of CO2, achieving C-C coupling by insertion of CO2 into -CH3. Owing to a combination of optoelectronic and catalytic properties, the assembly of AuIr with InGaN nanowires on silicon (AuIr@InGaN NWs/Si) enables the achievement of a C2H6 activity of 58.8 mmol‧g-1‧h-1 with a turnover number of 54,595 over 60 hours. A light-to-fuels efficiency of ~0.59% for solar fuels production from CO2 and H2O is achieved without any other energy inputs. This work provides a carbon-negative path for producing higher order C compounds.
- Keyword:
- Carbon dioxide reduction and Photocatalysis
- Discipline:
- Science
-
- Creator:
- Quartey, Nii-Boi A and Liemohn, Michael W
- Description:
- This dataset contains results from the BATS-R-US multispecies MHD code simulating the solar wind interaction at Mars at the following orbital and solar cycle locations: solar maximum at perihelion, solar maximum at aphelion, solar minimum at perihelion, solar minimum at aphelion. These simulations contain results with and without the crustal magnetic fields and includes variables such as the magnetic field and ion density.
- Keyword:
- mars, magnetosphere, magnetotail, current sheet, asymmetry, multispecies, multifluid, MHD, and MAVEN
- Discipline:
- Science