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- Creator:
- Skerlos, Steven J.
- Description:
- Supporting Information for research article "Life cycle comparison of environmental emissions from three disposal options for unused pharmaceutical". This spreadsheet provides the calculations and values used for this study; please refer to the manuscript and supporting information (as text) available at http://dx.doi.org/10.1021/es203987b for details about how to use this spreadsheet. We use life cycle assessment methodology to compare three disposal options for unused pharmaceuticals: (i) incineration after take-back to a pharmacy, (ii) wastewater treatment after toilet disposal, and (iii) landfilling or incineration after trash disposal. For each option, emissions of active pharmaceutical ingredients to the environment (API emissions) are estimated along with nine other types of emissions to air and water (non-API emissions). Under a scenario with 50% take-back to a pharmacy and 50% trash disposal, current API emissions are expected to be reduced by 93%. This is within 6% of a 100% trash disposal scenario, which achieves an 88% reduction. The 50% take-back scenario achieves a modest reduction in API emissions over a 100% trash scenario while increasing most non-API emissions by over 300%. If the 50% of unused pharmaceuticals not taken-back are toileted instead of trashed, all emissions increase relative to 100% trash disposal. Evidence suggests that 50% participation in take-back programs could be an upper bound. As a result, we recommend trash disposal for unused pharmaceuticals. A 100% trash disposal program would have similar API emissions to a take-back program with 50% participation, while also having significantly lower non-API emissions, lower financial costs, higher convenience, and higher compliance rates.
- Discipline:
- Engineering
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- Creator:
- Grosh, Karl and Li, Yizeng
- Description:
- In a sensitive cochlea, the basilar membrane response to transient excitation of any kind--normal acoustic or artificial intracochlear excitation--consists of not only a primary impulse but also a coda of delayed secondary responses with varying amplitudes but similar spectral content around the characteristic frequency of the measurement location. The coda, sometimes referred to as echoes or ringing, has been described as a form of local, short term memory which may influence the ability of the auditory system to detect gaps in an acoustic stimulus such as speech. Depending on the individual cochlea, the temporal gap between the primary impulse and the following coda ranges from once to thrice the group delay of the primary impulse (the group delay of the primary impulse is on the order of a few hundred microseconds). The coda is physiologically vulnerable, disappearing when the cochlea is compromised even slightly. The multicomponent sensitive response is not yet completely understood. We use a physiologically-based, mathematical model to investigate (i) the generation of the primary impulse response and the dependence of the group delay on the various stimulation methods, (ii) the effect of spatial perturbations in the properties of mechanically sensitive ion channels on the generation and separation of delayed secondary responses. The model suggests that the presence of the secondary responses depends on the wavenumber content of a perturbation and the activity level of the cochlea. In addition, the model shows that the varying temporal gaps between adjacent coda seen in experiments depend on the individual profiles of perturbations. Implications for non-invasive cochlear diagnosis are also discussed.
- Citation to related publication:
- http://dx.doi.org/10.1371/journal.pcbi.1005015
- Discipline:
- Engineering and Health Sciences
-
- Creator:
- Fries, Kevin J.
- Description:
- This data is in support of the WRR paper by Fries and Kerkez: Big Ship Data: Using Vessel Measurements to Improve Estimates of Temperature and Wind Speed on the Great Lakes Code is also provided
- Keyword:
- Gaussian process regression, Data integration, Wind speed, Water surface temperature, and Air temperature
- Citation to related publication:
- Fries, K., and B. Kerkez (2017), Big Ship Data: Using vessel measurements to improve estimates of temperature and wind speed on the Great Lakes, Water Resour. Res., 53, 3662–3679, http://doi.org/10.1002/2016WR020084.
- Discipline:
- Engineering
-
- Creator:
- University of Michigan Transportation Research Institute, Rupp, Jonathan D., Klein, Katelyn F., and Reed, Matthew P.
- Description:
- The files include an Excel file with the x-, y-, and z- coordinates that make up the nodal coordinates for a surface model of small (5th percentle) female pelvis geometry, the finite element model (.k file) that represents the nodal coordinates, and two surface files that represent the geometry (.obj and .ply).
- Citation to related publication:
- https://deepblue.lib.umich.edu/handle/2027.42/117574
- Discipline:
- Engineering
-
- Creator:
- Stoev, Stilian and Hu, Weifeng
- Description:
- Many data sets come as point patterns of the form (longitude, latitude, time, magnitude). The examples of data sets in this format includes tornado events, origins/destination of internet flows, earthquakes, terrorist attacks and etc. It is difficult to visualize the data with simple plotting. This research project studies and implements non-parametric kernel smoothing in Python as a way of visualizing the intensity of point patterns in space and time. A two-dimensional grid M with size mx, my is used to store the calculation result for the kernel smoothing of each grid points. The heat-map in Python then uses the grid to plot the resulting images on a map where the resolution is determined by mx and my. The resulting images also depend on a spatial and a temporal smoothing parameters, which control the resolution (smoothness) of the figure. The Python code is applied to visualize over 56,000 tornado landings in the continental U.S. from the period 1950 - 2014. The magnitudes of the tornado are based on Fujita scale.
- Discipline:
- Engineering and Science
-
- Creator:
- Figueroa, C. Alberto
- Description:
- Magnetic resonance angiography (MRA) of the aorta of a 30 yo healthy volunteer, segmented and discretized using the software CRIMSON ( www.crimson.software). Additionally, models corresponding to virtually-aged aortic geometries at ages: 40, 60, and 75.
- Keyword:
- Pulse Wave Velocity, Blood flow modeling, Hypertension, and Aging
- Citation to related publication:
- Cuomo F, Roccabianca S, Dillon-Murphy D, Xiao N, Humphrey JD, Figueroa CA (2017) Effects of age-associated regional changes in aortic stiffness on human hemodynamics revealed by computational modeling. PLoS ONE 12(3): e0173177. https://doi.org/10.1371/journal.pone.0173177
- Discipline:
- Engineering
-
- Creator:
- Larson, Ronald G., Wen, Fei, Huang, Wenjun, and Huang, Ming
- Description:
- We provide the parameters used in Umbrella Sampling simulations reported in our study "Efficient Estimation of Binding Free Energies between Peptides and an MHC Class II Molecule Using Coarse-Grained Molecular Dynamics Simulations with a Weighted Histogram Analysis Method", namely the set positions and spring constants for each window in simulations. Two tables are provided. Table 1 lists the names of the peptides and their corresponding sequences. Table 2 lists the parameters. The abstract of our work is the following: We estimate the binding free energy between peptides and an MHC class II molecule using molecular dynamics (MD) simulations with Weighted Histogram Analysis Method (WHAM). We show that, owing to its more thorough sampling in the available computational time, the binding free energy obtained by pulling the whole peptide using a coarse-grained (CG) force field (MARTINI) is less prone to significant error induced by biased-sampling than using an atomistic force field (AMBER). We further demonstrate that using CG MD to pull 3-4 residue peptide segments while leaving the remain-ing peptide segments in the binding groove and adding up the binding free energies of all peptide segments gives robust binding free energy estimations, which are in good agreement with the experimentally measured binding affinities for the peptide sequences studied. Our approach thus provides a promising and computationally efficient way to rapidly and relia-bly estimate the binding free energy between an arbitrary peptide and an MHC class II molecule.
- Keyword:
- Molecular Dynamics, Binding Free Energy, Protein, MHC, and Coarse-Grained
- Citation to related publication:
- M. Huang, W. Huang, F. Wen, R. G. Larson. J. Comput. Chem. 2017, 38, 2007–2019. https://doi.org/10.1002/jcc.24845
- Discipline:
- Science and Engineering
-
- Creator:
- Jones, Monica L.H.
- Description:
- This study evaluated the performance of a video-based intervention for improving the belt fit obtained by drivers. Previous laboratory studies have demonstrated that some drivers position their seat belts suboptimally. Specifically, the lap portion of the belt may be higher and farther forward relative to the pelvis than best practice, and the shoulder portion of the belt may be outboard or inboard of mid-shoulder. A video was developed to present the most important aspects of belt fit best practices, with emphasis on the lap belt. The video demonstrated how a seat belt should be routed with respect to an individual’s anatomy to ensure a proper fit. The three key belt fit concepts conveyed in the video were: 1) Lap belt low on hips, touching the thighs. 2) Shoulder belt crossing middle of collarbone. 3) Belt snug, as close to bones as possible. Additional context about the ability to achieve to good belt fit, such as opening a heavy coat or adjusting the height adjusters on the B-pillar behind the windows, were also presented.
- Keyword:
- Safety, Seatbelt Fit, Intervention, and Evaluation
- Citation to related publication:
- Jones, M.L.H., Ebert, S.M., Buckley, L., Park, J., and Reed, M.P. (2016). Evaluating an Intervention to Improve Belt Fit for Drivers. Technical Report UMTRI 2016-12. University of Michigan Transportation Research Institute, Ann Arbor, MI. , Reed, M.P., Ebert-Hamilton, S.M. and Rupp, J.D. (2012). Effects of obesity on seat belt fit. Traffic Injury Prevention, 13(4):364-372. https://doi.org/10.1080/15389588.2012.659363, Reed, M.P., Ebert, S.M. and Hallman, J.J. (2013). Effects of driver characteristics on seat belt fit. Stapp Car Crash Journal, 57:43-57., and Jones, M.L.H., Ebert, S.M., and Reed, M.P. (2015). Effects of High Levels of Obesity on Driver Seat Belt Fit. Advancing Transportation Leadership and Safety Technical Report ATLAS-2015-016. University of Michigan Transportation Research Institute, Ann Arbor, MI.
- Discipline:
- Engineering
-
- Creator:
- Grosky, William I. and Ruas, Terry L.
- Description:
- This dataset was used for a proof-of-concept of fixed lexical chain approach for semantic information retrieval.
- Keyword:
- fixed lexical chains
- Citation to related publication:
- Ruas, T. L., & Grosky, W. I. (2017). Exploring and expanding the use of lexical chains in information retrieval. Ann Arbor: University of Michigan. Retrieved from the Deep Blue institutional repository website: http://dx.doi.org/10.3998/2027.42/136659
- Discipline:
- Engineering
-
- Creator:
- Engel, Michael, Glotzer, Sharon C., Anderson, Joshua A., Antonaglia, James, and Millan, Jaime A.
- Description:
- This dataset was generated for our work "Shape and symmetry determine two-dimensional melting transitions of hard regular polygons". The dataset includes simulation results for 13 different polygons (equilateral triangles through regular tetradecagons and the 4-fold pentille) at a variety of packing fractions near the isotropic fluid to solid phase transition. Each trajectory contains the final 4 frames of each simulation run we conducted at system sizes of over one million particles. For each shape, there is a JSON file that describes the vertices of the polygon and a number of simulation trajectory files in GSD ( https://bitbucket.org/glotzer/gsd) format. The trajectory files contain the positions and orientations of all the polygons at each frame, along with the simulation box size. The trajectory file names identify the packing fraction of that simulation run.
- Discipline:
- Engineering
-
- Creator:
- Malik, Hafiz and Khan, Muhammad Khurran, King Saud University
- Description:
- Details of the microphone used for data collection, acoustic environment in which data was collected, and naming convention used are provided here. 1 - Microphones Used: The microphones used to collect this dataset belong to 7 different trademarks. Table (1) illustrates the number of used Mics of different trademarks and models. Table 1: Trademarks and models of Mics Mic Trademark Mic Model # of Mics Shure SM-58 3 Electro-Voice RE-20 2 Sennheiser MD-421 3 AKG C 451 2 AKG C 3000 B 2 Neumann KM184 2 Coles 4038 2 The t.bone MB88U 6 Total 22 2- Environment Description: A brief description of the 6 environments in which the dataset was collected is presented here: (i) Soundproof room: a small room (nearly 1.5m × 1.5m × 2m), which is closed and completely isolated. With an exception of a small window in the front side of the room which is made of glass, all the walls of the room are made of wood and covered by a layer of sponge from the inner side, and the floor is covered by carpet. (ii) Class room: standard class room (6m × 5m × 3m). (iii) Lab: small lab (4m × 4m × 3m). All the walls are made of glasses and the floor is covered by carpet. The lab contains 9 computers. (iv) Stairs: is in the second floor. The place of recording is 3m × 5m (v) Parking: is the college parking. (vi) Garden: is an open space outside the buildings. 3- Naming Convention: This set of rules were followed as a naming convention to give each file in the dataset a unique name: (i) The file name is 19 characters long, and consists of 5 sections separated by underscores. (ii) The first section is of 3 characters indicates the Microphone trademark. (iii) The second section of 4 characters indicates the microphone model as in table (2). (iv) The third section of 2 characters indicates a specific microphone within a set of microphones of the same trademark and model, since we have more than one microphone of the same trademark and model. (v) The fourth section of 2 characters indicates the environment, where Soundproof room --> 01 Class room --> 02 Lab --> 03 Stairs --> 04 Parking --> 05 Garden --> 06 (vi) The fifth section of 2 characters indicates the language, where Arabic --> 01 English --> 02 Chinese --> 03 Indonesian --> 04 (vii) The sixth section of 2 characters indicates the speaker. Table 2: Microphones Naming Criteria Original Mic Trademark and model --> Naming Convenient Shure SM-58 --> SHU_0058 Electro-Voice RE-20 --> ELE_0020 Sennheiser MD-421 --> SEN_0421 AKG C 451 --> AKG_0451 AKG C 3000 B --> AKG_3000 Neumann KM184 --> NEU_0184 Coles 4038 --> COL_4038 The t.bone MB88U --> TBO_0088 For example: SEN_0421_02_01_02_03 is an English file recorded by speaker number 3 in the soundproof room using microphone number 2 of Sennheiser MD-421
- Keyword:
- audio forensic, multimedia forensics, microphone identification, tamper detection, splicing detection, and codec identification
- Citation to related publication:
- http://dx.doi.org/10.1080/00450618.2017.1296186
- Discipline:
- Government, Politics and Law, Science, and Engineering
-
- Creator:
- Schiffmann, Philipp, Sick, Volker, and Reuss, David L
- Description:
- This archive contains data files from motored internal combustion engine experiments. Included are two-dimensional two-component velocity fields from four measurement planes with maximized field of view. in-cylinder pressure measurements, external pressure and temperature data, as well as details on the geometry of the optical engine to enable setups of simulation configurations. Motored operating conditions include 40kPa and 90kPa MAP, 800 and 1300 RPM.
- Keyword:
- TCC III engine, internal combustion engine, particle image velocimetry, in-cylinder flow, turbulence in engines, CFD validation data, motored engine, optical engine, cyclic variability , and PIV
- Citation to related publication:
- http://dx.doi.org/10.2516/ogst/2015028
- Discipline:
- Engineering
-
- Creator:
- Schiffmann, Philipp, Sick, Volker, and Reuss, David L
- Description:
- This archive contains data files from spark-ignited homogenous combustion internal combustion engine experiments. Included are two-dimensional two-component velocity fields acquired in a small, high-resolution field of view near the spark plug, and images of hydroxyl radical chemiluminescence recording the early flame-kernel growth. Included are in-cylinder pressure measurements, external pressure and temperature data, as well as details on the geometry of the optical engine to enable setups of simulation configurations. Included are tables of one-per-cycle parameters for each test with methane or propane at stoichiometric, dilute limit, lean limit, and rich limit, operation conducted at 40kPa and 1300 RPM.
- Keyword:
- OH* imaging, TCC III engine, internal combustion engine, particle image velocimetry, in-cylinder flow, turbulence in engines, CFD validation data, cyclic variability, early flame kernel growth, optical engine, combustion variability, ignition, and PIV
- Citation to related publication:
- dx.doi.org/10.1177/1468087417720558
- Discipline:
- Engineering
-
- Creator:
- Schiffmann, Philipp, Sick, Volker, and Reuss, David L
- Description:
- This archive contains data files from spark-ignited homogenous combustion internal combustion engine experiments. Included are two-dimensional two-component velocity fields from various measurement planes with maximized field of view, in-cylinder pressure measurements, external pressure and temperature data, as well as details on the geometry of the optical engine to enable setups of simulation configurations. Fired operation was with stoichiometric propane air, 40kPa MAP, at 1300 RPM.
- Keyword:
- TCC III engine, internal combustion engine, particle image velocimetry, in-cylinder flow, turbulence in engines, CFD validation data, cyclic variability, optical engine, combustion variability, and PIV
- Citation to related publication:
- dx.doi.org/10.1177/1468087417720558
- Discipline:
- Engineering
-
- Creator:
- Mathieu, Johanna L, Balzano, Laura, and Ledva, Gregory S
- Description:
- This data set contains the relevant time series for constructing and testing electricity load models within the related paper. The files within are a '.mat' file that contains the data and a 'readme.txt' file detailing the contents of the data.
- Keyword:
- Output feedback, Online learning, Machine learning, Real-time filtering, and Energy disaggregation
- Citation to related publication:
- https://arxiv.org/abs/1701.04389
- Discipline:
- Engineering
-
- Creator:
- Mathews, Elizabeth and Verhoff, Frank
- Description:
- Each pdf is an electronic version of the paper output for each experiment. Each text file is the electronic version of the data on the computer cards for each experiment. These text files are directly readable by Excel. Once in Excel, the data can be manipulated as desired. Additional information is in the theses.
- Keyword:
- Two Liquid Phase Processes, Droplet Size and Concentration, Population Balances, and Dispersed Phase Mixing
- Citation to related publication:
- Ross, S. L. (1971). Measurements and models of the dispersed phase mixing process (Doctoral dissertation). Retrieved from http://hdl.handle.net/2027.42/136886 and Verhoff, F. H. (1969). A study of the bivariate analysis of dispersed phase mixing (Doctoral dissertation). Retrieved from http://hdl.handle.net/2027.42/137651
- Discipline:
- Engineering and Science
-
- Creator:
- Fries, Kevin J
- Description:
- This data is in support of the publication in review "Using sensor data to dynamically map large-scale models to site-scale forecasts: A case study using the National Water Model". It is all the raw data extracted from the NWM flow forecasts for Iowa and the IFIS stage readings. For the NWM data, each date has it's own tab-delimited file with columns being the time (hrs) and rows being the NHD site. For the IFIS gages, each tab delimited file is for a single site for the period of record.
- Discipline:
- Engineering
-
- Creator:
- Regoli, Leonardo H.
- Description:
- The data contained in the file comprises those collected during the characterization of the sensor as described in the article "Investigation of a low-cost magneto-inductive magnetometer for space science applications" (cited below). This includes: , - Resolution , - Stability , - Linearity , - Frequency response, and Curation note: Addendum to README added June 1, 2018 regarding several files not used in preparing the manuscript with which the dataset is associated.
- Keyword:
- magnetometer, magnetic fields, CubeSat, and geomagnetic activity
- Citation to related publication:
- Regoli, L. H., Moldwin, M. B., Pellioni, M., Bronner, B., Hite, K., Sheinker, A., & Ponder, B. M.: Investigation of a low-cost magneto-inductive magnetometer for space science applications, Geosci. Instrum. Method. Data Syst., 7, 129-142, https://doi.org/10.5194/gi-2017-53, 2018.
- Discipline:
- Engineering
-
- Creator:
- Gliske, Stephen V and Stacey, William C
- Description:
- This data is part of a large program to translate detection and interpretation of HFOs into clinical use. A zip file is included which contains hfo detections, metadata, and Matlab scripts. The matlab scripts analyze this input data and produce figures as in the referenced paper (note: the blind source separation method is stochastic, and so the figures may not be exactly the same). A file "README.txt" provides more detail about each individual file within the zip file.
- Keyword:
- hfo, high frequency oscillation, ripple, fast ripple, blind source separation, non-negative matrix factorization, and temporal variability
- Citation to related publication:
- Stephen V. Gliske, Zachary T. Irwin, Cynthia Chestek, Garnett L. Hegeman, Benjamin Brinkmann, Oren Sagher, Hugh J. L. Garton, Greg A. Worrell, William C. Stacey. "Variability in the location of High Frequency Oscillations during prolonged intracranial EEG recordings." Nature Communications. https://doi.org/10.1038/s41467-018-04549-2
- Discipline:
- Health Sciences, Science, and Engineering
-
- Creator:
- Nguyen, Thanh H., Wright, Mason, Wellman, Michael P., and Singh, Satinder
- Description:
- In this work , we study the problem of allocating limited security countermeasures to protect network data from cyber-attacks, for scenarios modeled by Bayesian attack graphs. We consider multi-stage interactions between a network administrator and cybercriminals, formulated as a security game. We propose parameterized heuristic strategies for the attacker and defender and provide detailed analysis of their time complexity. Our heuristics exploit the topological structure of attack graphs and employ sampling methods to overcome the computational complexity in predicting opponent actions. Due to the complexity of the game, we employ a simulation-based approach and perform empirical game analysis over an enumerated set of heuristic strategies. Finally, we conduct experiments in various game settings to evaluate the performance of our heuristics in defending networks, in a manner that is robust to uncertainty about the security environment.
- Keyword:
- Empirical Game-Theoretic Analysis, Multi-stage Security Games, Attack Graph, Game Theory, and Moving Target Defense
- Citation to related publication:
- Nguyen, T. H., Wright, M., Wellman, M. P., & Singh, S. (2017). Multi-stage attack graph security games: Heuristic strategies, with empirical game-theoretic analysis. In MTD 2017 - Proceedings of the 2017 Workshop on Moving Target Defense, co-located with CCS 2017 (Vol. 2017-January, pp. 87-97). Association for Computing Machinery, Inc. https://doi.org/10.1145/3140549.3140562
- Discipline:
- Science and Engineering