This project aimed to discover and analyze the molecular mechanism of synthesis of two particular fucosylated oligosaccharide products in a mutant enzyme, Thermatoga maratima Alpha-L-Fucosidase D224G, whose wild type performs the opposite reaction (cleavage of fucosyl glycosidic bonds). Discovery of the mechanism was performed using an unbiased simulations method known as aimless shooting, whereas analysis of the mechanism in terms of the energy profile was performed using a separate method known as equilibrium path sampling. The data here concerns the latter method. and The contents of the atesa_master.zip are the ATESA GitHub project. A Python program for automating transition path sampling with aimless shooting using Amber. https://github.com/team-mayes/atesa
Internally administered targeted radionuclide therapy (TRT) with radio-labelled targeting molecules that deliver cytotoxic radiation to tumor has been used successfully to treat multiple cancers. Lu-177, used increasingly in TRT, emits both beta particles that deliver the therapeutic effect. FDA recently approved a fixed activity (4 cycles of 7.4 GBq/cycle as in NETTER -1) administered every 8 weeks. With the patient studies under this treatment, we collected CT images and corresponding volume of interest (organs, lesions) contours.
Files contain the atmospheric CO2 mole fraction responses to land flux type (HRcasa, HRcorpse, HRmimics) and land flux region (latband variable). Land flux regions are categorized as: Northern Hemisphere high latitudes (NHL; 61 to 90°N), midlatitudes (NML; 24 to 60°N), tropics (NT; 1 to 23°N), Southern Hemisphere tropics (ST; 0 to 23°S), and extratropics (SE; 24 to 90°S). See the README file for how these land flux region definitions relate to the file's latband variable. and To cite dataset: Basile, S., Lin, X., Keppel-Aleks, G. (2019). Simulated CO2 dataset using the atmospheric transport model GEOSChem v12.0.0: Response to regional land carbon fluxes [Data set]. University of Michigan - Deep Blue. https://doi.org/10.7302/xjzc-xy05
Model simulations were conducted to investigate the role of soil moisture on the terrestrial carbon and water cycles. The data are composed of NetCDF files generated by the simulations that contain the data variables analyzed in the paper. and CLM5 Documentation - http://www.cesm.ucar.edu/models/cesm2/land/.
We compared the response rates, cost, and the average income of participants pertaining to 6 different survey distribution methods used in an initial study about mobility-on-demand services. We used the data to identify survey and recruitment methods that are more effective in reaching hard-to-reach populations. All the raw data used for calculations and the calculations themselves can be found in the attached spreadsheets. and Initial analyses have identified in-person onsite recruitment as one of the better methods of reaching hard-to-reach populations, and is calling for continued work in improving research methods in the field of HCI.
The project outputs summarize all the publications, talks, and codes we accomplished under this NSF funding. In the project, we develop methodologies to manage uncertainty in future electric power systems and quantify how uncertainty affects power system sustainability. and Talks, papers, and poster in Deep Blue: http://hdl.handle.net/2027.42/149653
SWMF is used to study the segmentation of SED plume into polar cap patches during the geomagnetic storm on Sep 7, 2017. The database includes the 3D output in the upper atmosphere from GITM, the 2D output from Ionospheric Electrodynamics (IE) and 3D output from BATSRUS. The output from GITM can be read with thermo_batch_new.pro. The output from IE can be opened with Spacepy at https://pythonhosted.org/SpacePy/. The output from BATSRUS can be opened with tecplot.
More details can be found in Readme.txt.
This is the code that resulted from NSF grant ECCS-1508943, "Inferring the behavior of distributed energy resources from incomplete measurements." The project focused on developing control, estimation, and modeling methods for residential demand response and electric distribution networks.
The talks, papers, and poster in Deep Blue: http://hdl.handle.net/2027.42/149480
Manganese in the sedimentary record has been interpreted by many as a powerful redox proxy for paleoenvironments, and yet very little work has been done to ensure that the manganese-rich minerals in the rock record are actually recording primary signals. In the accompanying manuscript, we present an in-depth characterization of the manganese mineralogy from two correlated regions recording the Transvaal Supergroup in South Africa with markedly different alteration histories to investigate if there can be post-depositional emplacement of manganese-rich minerals. The data uploaded here are X-ray absorption spectra of (1) manganese standard minerals that were useful in our analyses and (2) minerals from an important well-characterized sample that may be useful as comparative standards in future studies.