Scan of specimen ummz:mammals:123037 (Tscherskia TRITON) - WholeBody. Raw Dataset includes 1601 TIF images (each 715 x 1288 x 1 voxel at 0.0493711582967448 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction. and Scan of specimen ummz:mammals:123037 (Tscherskia TRITON) - WholeBody. Reconstructed Dataset includes 2000 TIF images (each 715 x 1288 x 1 voxel at 0.049371 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction.
Scan of specimen ummz:mammals:111984 (Handleyomys ALFAROI ALFAROI) - WholeBody. Raw Dataset includes 1601 TIF images (each 815 x 1310 x 1 voxel at 0.0421497172804555 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction. and Scan of specimen ummz:mammals:111984 (Handleyomys ALFAROI ALFAROI) - WholeBody. Reconstructed Dataset includes 2000 TIF images (each 815 x 1310 x 1 voxel at 0.042150 mm resolution, derived from 1601 scan projections), xtek and vgi files for volume reconstruction.
Scientists often try to reproduce observations with a model, helping them explain the observations by adjusting known and controllable features within the model. They then use a large variety of metrics for assessing the ability of a model to reproduce the observations. One such metric is called the relative operating characteristic (ROC) curve, a tool that assesses a model’s ability to predict events within the data. The ROC curve is made by sliding the event-definition threshold in the model output, calculating certain metrics and making a graph of the results. Here, a new model assessment tool is introduced, called the sliding threshold of observation for numeric evaluation (STONE) curve. The STONE curve is created by sliding the event definition threshold not only for the model output but also simultaneously for the data values. This is applicable when the model output is trying to reproduce the exact values of a particular data set. While the ROC curve is still a highly valuable tool for optimizing the prediction of known and pre-classified events, it is argued here that the STONE curve is better for assessing model prediction of a continuous-valued data set.
and Data and code were created using IDL, but can also be accessed with the open-source Gnu Data Language (GDL; see https://github.com/gnudatalanguage/gdl)
Liemohn, M. W., Azari, A. R., Ganushkina, N. Yu., & Rastätter, L. (2020). The STONE curve: A ROC-derived model performance assessment tool. Earth and Space Science, 7, e2020EA001106. https://doi.org/10.2019/2020EA001106
The editorial decision process for the Journal of Geophysics Research Space Physics is assisted by over 1,000 scientists every year, providing over 3,000 reviews per year. These statistics are presented for the years 2013 through 2018, showing some fluctuations but, overall, consistency in the response of the space physics research community to requests to serve as manuscript reviewers. Over half of these reviews are submitted on time, and the average time to review actually dropped as the load increased. This is greatly appreciated and the community is to be commended and thanked for their willingness to help make this journal thrive and remain a premiere publication in the field.
The Division of Reptiles and Amphibians maintains a collection that is worldwide in scope. The research collections contain over 200,000 catalogued lots representing approximately 435,000 individual specimens.
The Division of Mammals at the Museum of Zoology was established in 1837, and has grown steadily to its current size, with over 150,000 specimens. An important feature of the mammal collection at the Museum of Zoology is our emphasis on non-traditional specimens.
The University of Michigan Museum of Zoology (UMMZ) is the center for the study of animal diversity on campus, focusing on the evolutionary origins of the planet’s animal species, the genetic information they contain and the communities and ecosystems they help form. Now an integral part of the Department of Ecology and Evolutionary Biology (EEB), the UMMZ houses world-class collections, containing more than 15 million specimens, span almost 200 years of regional and global biodiversity studies and that support a multi-faceted Departmental research and teaching program.
Craniosynostosis is the premature fusion of cranial bones. The goal of this study was to determine if delivery of recombinant tissue nonspecific alkaline phosphatase (TNAP) could prevent or diminish the severity of craniosynostosis in a C57BL/6 FGFR2C342Y/+ model of neonatal onset craniosynostosis or a BALB/c FGFR2C342Y/+ model of postnatal onset craniosynostosis. Mice were injected with a lentivirus encoding a mineral targeted form of TNAP immediately after birth. Cranial bone fusion as well as cranial bone volume, mineral content and density were assessed by micro computed tomography. Craniofacial shape was measured with calipers., Alkaline phosphatase, alanine amino transferase (ALT) and aspartate amino transferase (AST) activity levels were measured in serum. Neonatal delivery of TNAP diminished craniosynostosis severity from 94% suture obliteration in vehicle treated mice to 67% suture obliteration in treated mice, p<0.02) and the incidence of malocclusion from 82.4% to 34.7% (p<0.03), with no effect on cranial bone in C57BL/6 FGFR2C342Y/+ mice. In contrast, treatment with TNAP improved cranial bone volume (p< 0.01), density (p< 0.01) and mineral content (p< 0.01) but had no effect on craniosynostosis or malocclusion in BALB/c FGFR2C342Y/+ mice. , These results indicate that post-natal recombinant TNAP enzyme therapy diminishes craniosynostosis severity in the C57BL/6 FGFR2C342Y/+ neonatal onset mouse model of Crouzon syndrome, and that effects of exogenous TNAP are genetic background dependent., and Included in this collection is one set of images representing the C57BL/6 FGFR2C342Y/+ model of neonatal onset craniosynostosis, and one for the BALB/c FGFR2C342Y/+ model of postnatal onset craniosynostosis
The data file contains (1) the grayscale images of the nano-tomography experiments that can be segmented into binary images and visualized to show the 3D morphology of spiral eutectics; and (2) crystallographic orientation maps of serial-sectioned sample, which can be processed in a variety of EBSD software packages.