Work Description

Title: Dataset: Models generated for the bioinformatic analysis of MPER/protein fusions binding to antibody Open Access Deposited

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Attribute Value
Methodology
  • This dataset includes atomic coordinates (.pdb files) for bioinformatic models of antibody fragment binding to an MPER epitope – membrane protein fusion. For each membrane protein subject, MPER fusion was evaluated in several different registers, and evaluated for binding by four different antibody fragments. A model is provided for each fusion register and antibody fragment. More details about the methodology used in generating this data set are included in the readme file.
Description
  • This project evaluated the binding of antibody fragments to membrane proteins fused to a short epitope sequence (“MPER”). This dataset includes atomic coordinates (.pdb files) for bioinformatic models of antibody fragment binding to an MPER epitope – membrane protein fusion.
Creator
Depositor
  • stockbr@umich.edu
Contact information
Discipline
Funding agency
  • National Institutes of Health (NIH)
ORSP grant number
  • NIH grant R35GM128768 to Randy B. Stockbridge, Intramural Research Program of the Vaccine Research Center, NIAID, NIH to Peter D. Kwong
Keyword
Citations to related material
  • McIlwain, B. C., Erwin, A. L., Davis, A. R., Ben Koff, B., Chang, L., Bylund, T., Chuang, G.-Y., Kwong, P. D., Ohi, M. D., Lai, Y.-T., & Stockbridge, R. B. (2021). N-terminal Transmembrane-Helix Epitope Tag for X-ray Crystallography and Electron Microscopy of Small Membrane Proteins. Journal of Molecular Biology, 166909. https://doi.org/10.1016/j.jmb.2021.166909
Resource type
Last modified
  • 11/19/2022
Published
  • 02/19/2021
Language
DOI
  • https://doi.org/10.7302/7ym7-gp78
License
To Cite this Work:
Bylund, T., Chuang, G., Kwong, P., Lai, Y., McIlwain, B., Stockbridge, R. B. (2021). Dataset: Models generated for the bioinformatic analysis of MPER/protein fusions binding to antibody [Data set], University of Michigan - Deep Blue Data. https://doi.org/10.7302/7ym7-gp78

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Files (Count: 2; Size: 1.04 GB)

Thumbnailthumbnail-column Title Original Upload Last Modified File Size Access Actions
Readme.pdf 2021-02-18 2021-02-20 413 KB Open Access
bio_unit_mper_mmbrn.zip 2020-09-04 2020-09-04 1.04 GB Open Access

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