Work Description

Title: Data for "The Coda of the Transient Response in a Sensitive Cochlea" Open Access Deposited

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Attribute Value
Methodology
  • We used a finite element approximation of a physiologically-based, mechano-electro-acoustical model for a gerbil cochlea to simulate the response of the cochlea to internal and normal external stimulation.
Description
  • In a sensitive cochlea, the basilar membrane response to transient excitation of any kind--normal acoustic or artificial intracochlear excitation--consists of not only a primary impulse but also a coda of delayed secondary responses with varying amplitudes but similar spectral content around the characteristic frequency of the measurement location. The coda, sometimes referred to as echoes or ringing, has been described as a form of local, short term memory which may influence the ability of the auditory system to detect gaps in an acoustic stimulus such as speech. Depending on the individual cochlea, the temporal gap between the primary impulse and the following coda ranges from once to thrice the group delay of the primary impulse (the group delay of the primary impulse is on the order of a few hundred microseconds). The coda is physiologically vulnerable, disappearing when the cochlea is compromised even slightly. The multicomponent sensitive response is not yet completely understood. We use a physiologically-based, mathematical model to investigate (i) the generation of the primary impulse response and the dependence of the group delay on the various stimulation methods, (ii) the effect of spatial perturbations in the properties of mechanically sensitive ion channels on the generation and separation of delayed secondary responses. The model suggests that the presence of the secondary responses depends on the wavenumber content of a perturbation and the activity level of the cochlea. In addition, the model shows that the varying temporal gaps between adjacent coda seen in experiments depend on the individual profiles of perturbations. Implications for non-invasive cochlear diagnosis are also discussed.
Creator
Depositor
  • yizengli@umich.edu
Contact information
Discipline
Citations to related material
  • Li, Yizeng, and Karl Grosh. “The Coda of the Transient Response in a Sensitive Cochlea: A Computational Modeling Study.” PLOS Computational Biology 12, no. 7 (July 5, 2016): e1005015. https://doi.org/10.1371/journal.pcbi.1005015
Resource type
Curation notes
  • On 2/24/2020, updated "Citation to related material" to include full citation to related publication, not just DOI. No other changes were made to Work.
Last modified
  • 02/24/2020
Published
  • 06/10/2016
DOI
  • https://doi.org/10.7302/dpv8-4r68
License
To Cite this Work:
Grosh, K., Li, Y. (2016). Data for "The Coda of the Transient Response in a Sensitive Cochlea" [Data set], University of Michigan - Deep Blue Data. https://doi.org/10.7302/dpv8-4r68

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Files (Count: 16; Size: 270 MB)

Thumbnailthumbnail-column Title Original Upload Last Modified File Size Access Actions
readme.txt 2017-01-23 2017-01-23 2.53 KB Open Access
Random Profiles.xlsx 2016-06-10 2016-06-10 44 KB Open Access
Random_wavenumber.m 2016-06-10 2016-06-10 597 Bytes Open Access
acoustic_0.9active_1250_200.mat 2016-06-10 2016-06-10 24.9 MB Open Access
acoustic_0.9active_2.0r1G_1250_200.mat 2016-06-10 2016-06-10 24.9 MB Open Access
acoustic_0.9active_2.0r2G_1250_200.mat 2016-06-10 2016-06-10 24.9 MB Open Access
acoustic_0.9active_12deltaGat2.5...0.mat 2016-06-10 2016-06-10 24.9 MB Open Access
pres2.5mm_above_0.9active_1250_200.mat 2016-06-10 2016-06-10 24.1 MB Open Access
pres2.5mm_below_0.9active_1250_200.mat 2016-06-10 2016-06-10 24.2 MB Open Access
pres2.5mm_above_0.9active_2.0r1G...0.mat 2016-06-10 2016-06-10 24.1 MB Open Access
pres2.5mm_below_0.9active_2.0r2G...0.mat 2016-06-10 2016-06-10 24.2 MB Open Access
pres2.5mm_above_0.9active_2.0r2G...0.mat 2016-06-10 2016-06-10 24.1 MB Open Access
pres2.5mm_below_0.9active_2.0r1G...0.mat 2016-06-10 2016-06-10 24.2 MB Open Access
force2.5mm_0.9active_1250_200.mat 2016-06-10 2016-06-10 25 MB Open Access
spectrum_plot.m 2016-06-10 2016-06-10 641 Bytes Open Access
temporal_plot.m 2016-06-10 2017-01-23 5.42 KB Open Access

Read Me

This set of data produces the figures in the paper titled "The Coda of the Transient Response in a Sensitive Cochlea: A Computational Modeling Study." The following explains what each file is.

In all of the Matlab data files:
ubm: the displacement of the BM in cm. There are 441 longitudinal data point for each frequency.
ust: the displacement of the stapes in cm.
There are 1250 frequency steps beginning with 200 Hz, and the frequency increment is also 200 Hz.

Random Profiles.xlsx
This is the random profiles for R1 and R2 seen in Fig.3 in the paper.

Random_wavenumber.m
This m file is used to generate the spectrum of the random numbers shown in Fig.11.

acoustic_0.9active_1250_200.mat
This file contains the impulse acoustic response of the smooth system. It is used to generate Fig.4AB and Fig.9AB.

acoustic_0.9active_2.0r1G_1250_200.mat
This file contains the impulse acoustic response of the system under R1. It is used to generate Fig.4CD and Fig.5A.

acoustic_0.9active_2.0r2G_1250_200.mat
This file contains the impulse acoustic response of the system under R2. It is used to generate Fig.4EF, Fig.5B, and Fig.6AB.

acoustic_0.9active_12deltaGat2.5mm_1250_200.mat
This file contains the impulse acoustic response of the system under a localized perturbation. It is used to generate Fig.7 and Fig.9CD.

pres2.5mm_above_0.9active_1250_200.mat
pres2.5mm_below_0.9active_1250_200.mat
These two files contain the internal heating response of the smooth system. They are used to generate Fig.8A. A linear combination of these two with fractions of 0.52(below) and 0.48(above) is needed.

pres2.5mm_above_0.9active_2.0r1G_1250_200.mat
pres2.5mm_below_0.9active_2.0r2G_1250_200.mat
These two files contain the internal heating response of the system under R1. They are used to generate Fig.8B. A linear combination of these two with fractions of 0.52(below) and 0.48(above) is needed.

pres2.5mm_above_0.9active_2.0r2G_1250_200.mat
pres2.5mm_below_0.9active_2.0r1G_1250_200.mat
These two files contain the internal heating response of the system under R2. They are used to generate Fig.8C. A linear combination of these two with fractions of 0.52(below) and 0.48(above) is needed.

force2.5mm_0.9active_1250_200.mat
This file contains the impulse response under an internal force. It is used to generate Fig.10B.

spectrum_plot.m
This m file is used to read the mat files and generate the corresponding spectral plot.

Temporal_plot.m
This m file is used to read the mat files and generate the corresponding temporal plot.

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