<1. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24732494 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Glassman D AU - White L AU - Lewis A AU - King H AU - Clarke A AU - Glassman T AU - Comstock B AU - Hannaford B AU - Lendvay TS FA - Glassman, Deanna FA - White, Lee FA - Lewis, Andrew FA - King, Hawkeye FA - Clarke, Alicia FA - Glassman, Thomas FA - Comstock, Bryan FA - Hannaford, Blake FA - Lendvay, Thomas S IN - Glassman, Deanna. University of Washington School of Medicine. IN - White, Lee. University of Washington Biorobotics Laboratory. IN - Lewis, Andrew. University of Washington Biorobotics Laboratory. IN - King, Hawkeye. University of Washington Biorobotics Laboratory. IN - Clarke, Alicia. University of Washington Biorobotics Laboratory. IN - Glassman, Thomas. Albers School of Business & Economics; Seattle University. IN - Comstock, Bryan. University of Washington Department of Biostatistics. IN - Hannaford, Blake. University of Washington Biorobotics Laboratory. IN - Lendvay, Thomas S. Department of Urology, University of Washington. TI - Raven surgical robot training in preparation for da vinci. SO - Studies in Health Technology & Informatics. 196:135-41, 2014 AS - Stud Health Technol Inform. 196:135-41, 2014 NJ - Studies in health technology and informatics PI - Journal available in: Print PI - Citation processed from: Internet JC - ck1, 9214582 IO - Stud Health Technol Inform SB - Health Technology Assessment Journals CP - Netherlands MH - Adult MH - *Clinical Competence MH - Female MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - *Robotic Surgical Procedures/is [Instrumentation] MH - Students, Medical MH - Young Adult AB - The rapid adoption of robotic assisted surgery challenges the pace at which adequate robotic training can occur due to access limitations to the da Vinci robot. Thirty medical students completed a randomized controlled trial evaluating whether the Raven robot could be used as an alternative training tool for the Fundamentals of Laparoscopic Surgery (FLS) block transfer task on the da Vinci robot. Two groups, one trained on the da Vinci and one trained on the Raven, were tested on a criterion FLS block transfer task on the da Vinci. After robotic FLS block transfer proficiency training there was no statistically significant difference between path length (p=0.39) and economy of motion scores (p=0.06) between the two groups, but those trained on the da Vinci did have faster task times (p=0.01). These results provide evidence for the value of using the Raven robot for training prior to using the da Vinci surgical system for similar tasks. IS - 0926-9630 IL - 0926-9630 PT - Journal Article PT - Randomized Controlled Trial PP - ppublish LG - English DP - 2014 DC - 20140415 EZ - 2014/04/16 06:00 DA - 2017/04/19 06:00 DT - 2014/04/16 06:00 YR - 2014 ED - 20170418 RD - 20170418 UP - 20170420 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24732494 <2. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27493469 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Schiff L AU - Tsafrir Z AU - Aoun J AU - Taylor A AU - Theoharis E AU - Eisenstein D FA - Schiff, Lauren FA - Tsafrir, Ziv FA - Aoun, Joelle FA - Taylor, Andrew FA - Theoharis, Evan FA - Eisenstein, David IN - Schiff, Lauren. Division of Advanced Laparoscopy and Pelvic Pain, Department of Obstetrics and Gynecology. University of North Carolina, Chapel Hill, North Carolina, USA. IN - Tsafrir, Ziv. Division of Minimally Invasive Gynecology, Women's Health Services, Henry Ford Hospital, West Bloomfield, Michigan, USA. IN - Aoun, Joelle. Division of Minimally Invasive Gynecology, Women's Health Services, Henry Ford Hospital, West Bloomfield, Michigan, USA. IN - Taylor, Andrew. Division of Biostatistics, Public Health Sciences, Henry Ford Health System, Detroit, Michigan, USA. IN - Theoharis, Evan. Division of Minimally Invasive Gynecology, Women's Health Services, Henry Ford Hospital, West Bloomfield, Michigan, USA. IN - Eisenstein, David. Division of Minimally Invasive Gynecology, Women's Health Services, Henry Ford Hospital, West Bloomfield, Michigan, USA. TI - Quality of Communication in Robotic Surgery and Surgical Outcomes. SO - Journal of the Society of Laparoendoscopic Surgeons. 20(3), 2016 Jul-Sep AS - J Soc Laparoendosc Surg. 20(3), 2016 Jul-Sep NJ - JSLS : Journal of the Society of Laparoendoscopic Surgeons PI - Journal available in: Print PI - Citation processed from: Internet JC - 100884618, c8o IO - JSLS PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949353 SB - Index Medicus CP - United States MH - Adult MH - Blood Loss, Surgical MH - *Communication MH - *Gynecologic Surgical Procedures/st [Standards] MH - Humans MH - *Interprofessional Relations MH - Middle Aged MH - Operative Time MH - *Patient Care Team/st [Standards] MH - Pilot Projects MH - Postoperative Complications/ep [Epidemiology] MH - Principal Component Analysis MH - Prospective Studies MH - Quality Assurance, Health Care MH - Quality Indicators, Health Care/sn [Statistics & Numerical Data] MH - *Robotic Surgical Procedures/st [Standards] KW - *Communication; *Gynecology; *Robotic surgery; *Surgical outcomes; *Teamwork AB - BACKGROUND AND OBJECTIVES: Robotic surgery has introduced unique challenges to surgical workflow. The association between quality of communication in robotic-assisted laparoscopic surgery and surgical outcomes was evaluated. AB - METHODS: After each gynecologic robotic surgery, the team members involved in the surgery completed a survey regarding the quality of communication. A composite quality-of-communication score was developed using principal component analysis. A higher composite quality-of-communication score signified poor communication. Objective parameters, such as operative time and estimated blood loss (EBL), were gathered from the patient's medical record and correlated with the composite quality-of-communication scores. AB - RESULTS: Forty robotic cases from March through May 2013 were included. Thirty-two participants including surgeons, circulating nurses, and surgical technicians participated in the study. A higher composite quality-of-communication score was associated with greater EBL (P = .010) and longer operative time (P = .045), after adjustment for body mass index, prior major abdominal surgery, and uterine weight. Specifically, for every 1-SD increase in the perceived lack of communication, there was an additional 51 mL EBL and a 31-min increase in operative time. The most common reasons reported for poor communication in the operating room were noise level (28/36, 78%) and console-to-bedside communication problems (23/36, 64%). AB - CONCLUSION: Our study demonstrates a significant association between poor intraoperative team communication and worse surgical outcomes in robotic gynecologic surgery. Employing strategies to decrease extraneous room noise, improve console-to-bedside communication and team training may have a positive impact on communication and related surgical outcomes. ES - 1938-3797 IL - 1086-8089 DI - e2016.00026 DI - JSLS.2016.00026 DO - https://dx.doi.org/10.4293/JSLS.2016.00026 PT - Clinical Trial PT - Journal Article ID - 10.4293/JSLS.2016.00026 [doi] ID - JSLS.2016.00026 [pii] ID - PMC4949353 [pmc] PP - ppublish LG - English DP - 2016 Jul-Sep DC - 20160805 EZ - 2016/08/06 06:00 DA - 2017/04/15 06:00 DT - 2016/08/06 06:00 YR - 2016 ED - 20170414 RD - 20170414 UP - 20170417 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=27493469 <3. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27568160 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Korst RJ AU - Lee BE FA - Korst, Robert J FA - Lee, Benjamin E IN - Korst, Robert J. The Daniel and Gloria Blumenthal Cancer Center, Paramus, New Jersey; Department of Surgery, The Valley Hospital/Valley Health System, Ridgewood, New Jersey. Electronic address: korsro@valleyhealth.com. IN - Lee, Benjamin E. The Daniel and Gloria Blumenthal Cancer Center, Paramus, New Jersey. TI - Robotic Assisted Thoracic Surgery Lobectomy versus Video Assisted Thoracic Surgery Lobectomy: Is a Randomized Trial Really Necessary?. SO - Seminars in Thoracic & Cardiovascular Surgery. 28(1):193-4, 2016 Spring AS - Semin Thorac Cardiovasc Surg. 28(1):193-4, 2016 Spring NJ - Seminars in thoracic and cardiovascular surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - a2l, 8917640 IO - Semin. Thorac. Cardiovasc. Surg. SB - Index Medicus CP - United States MH - Humans MH - *Lung Neoplasms/su [Surgery] MH - *Pneumonectomy/mt [Methods] MH - Randomized Controlled Trials as Topic MH - *Robotic Surgical Procedures MH - *Thoracic Surgery, Video-Assisted ES - 1532-9488 IL - 1043-0679 DI - S1043-0679(16)30016-8 DO - https://dx.doi.org/10.1053/j.semtcvs.2016.04.012 PT - Comparative Study PT - Editorial ID - S1043-0679(16)30016-8 [pii] ID - 10.1053/j.semtcvs.2016.04.012 [doi] PP - ppublish PH - 2016/04/21 [accepted] LG - English EP - 20160426 DP - 2016 Spring DC - 20160829 EZ - 2016/08/29 06:00 DA - 2017/04/14 06:00 DT - 2016/08/29 06:00 YR - 2016 ED - 20170413 RD - 20170413 UP - 20170417 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=27568160 <4. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27247200 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Minig L AU - Zanagnolo V AU - Cardenas-Rebollo JM AU - Colombo N AU - Maggioni A FA - Minig, L FA - Zanagnolo, V FA - Cardenas-Rebollo, J M FA - Colombo, N FA - Maggioni, A IN - Minig, L. Gynecology Department, Valencian Institute of Oncology (IVO), Valencia, Spain. Electronic address: miniglucas@gmail.com. IN - Zanagnolo, V. Gynecology Department, European Institute of Oncology (IEO), Milan, Italy. IN - Cardenas-Rebollo, J M. Department of Applied Mathematics and Statistics CEU San Pablo University, Madrid, Spain. IN - Colombo, N. Gynecology Department, European Institute of Oncology (IEO), Milan, Italy. IN - Maggioni, A. Gynecology Department, European Institute of Oncology (IEO), Milan, Italy. TI - Feasibility of robotic radical hysterectomy after neoadjuvant chemotherapy in women with locally advanced cervical cancer. SO - European Journal of Surgical Oncology. 42(9):1372-7, 2016 Sep AS - Eur J Surg Oncol. 42(9):1372-7, 2016 Sep NJ - European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 8504356, eur IO - Eur J Surg Oncol SB - Index Medicus CP - England MH - Adenocarcinoma/pa [Pathology] MH - *Adenocarcinoma/th [Therapy] MH - Adult MH - *Antineoplastic Combined Chemotherapy Protocols/tu [Therapeutic Use] MH - Carcinoma, Squamous Cell/pa [Pathology] MH - *Carcinoma, Squamous Cell/th [Therapy] MH - Cisplatin/ad [Administration & Dosage] MH - Cisplatin/tu [Therapeutic Use] MH - Epirubicin/ad [Administration & Dosage] MH - Feasibility Studies MH - Female MH - Humans MH - *Hysterectomy/mt [Methods] MH - Ifosfamide/tu [Therapeutic Use] MH - Longitudinal Studies MH - Middle Aged MH - *Neoadjuvant Therapy MH - Paclitaxel/ad [Administration & Dosage] MH - Retrospective Studies MH - *Robotic Surgical Procedures/mt [Methods] MH - Taxoids/tu [Therapeutic Use] MH - Uterine Cervical Neoplasms/pa [Pathology] MH - *Uterine Cervical Neoplasms/th [Therapy] KW - *Abdominal radical hysterectomy; *Cervical cancer; *Complications; *Neoadjuvant chemotherapy; *Robotic radical hysterectomy AB - OBJECTIVE: To evaluate the safety and feasibility of robotic radical hysterectomy (RRH) in women with locally advanced cervical cancer (LACC) after neoadjuvant chemotherapy (NACT). AB - MATERIAL AND METHODS: A retrospective comparative longitudinal observational study was performed in 30 patients with LACC FIGO stage IB2-IIB who underwent RRH after NACT between February 2008 and September 2014. This group was compared with a cohort of 176 patients underwent RRH with cervical cancer FIGO stage IA2-IB1 in the same period of time. AB - RESULTS: Patients' age, BMI, ASA score, comorbidity, and previous abdominal surgery, was similar between groups. FIGO stage significantly differed between groups; 29 (96.6%) of patients had FIGO stage IB2 in NACT group and 163 (92.6%) were FIGO stag IB1 in women without NACT, p < 0.001. Type of RRH was also significantly different between groups. Type C1 RRH was significantly more common in NACT group, p = 0.015. Mean (SD) tumor size was significantly bigger in NACT, 27.0 (13.7) mm versus 20.9 (9.0) mm in early stage versus LACC, respectively. p = 0.023. Mean (SD) surgical time was significantly longer in NACT group (307.8 (40.2) min versus 277.4 (45.4) min, p = 0.001). Estimated blood loss and length of the hospital stay were similar between groups. There were no significant differences in terms of intraoperative and postoperative complications. AB - CONCLUSIONS: RRH after NACT in women with LACC seems to be safe and feasible. These results need to be confirmed in studies with a larger patients sample. AB - Copyright © 2016 Elsevier Ltd. All rights reserved. RN - 0 (Taxoids) RN - 3Z8479ZZ5X (Epirubicin) RN - P88XT4IS4D (Paclitaxel) RN - Q20Q21Q62J (Cisplatin) RN - UM20QQM95Y (Ifosfamide) PS - TIP regimen ES - 1532-2157 IL - 0748-7983 DI - S0748-7983(16)30149-4 DO - https://dx.doi.org/10.1016/j.ejso.2016.04.060 PT - Comparative Study PT - Journal Article PT - Observational Study ID - S0748-7983(16)30149-4 [pii] ID - 10.1016/j.ejso.2016.04.060 [doi] PP - ppublish PH - 2015/12/29 [received] PH - 2016/03/03 [revised] PH - 2016/04/18 [accepted] LG - English EP - 20160518 DP - 2016 Sep DC - 20160827 EZ - 2016/06/02 06:00 DA - 2017/04/11 06:00 DT - 2016/06/02 06:00 YR - 2016 ED - 20170410 RD - 20170410 UP - 20170412 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=27247200 <5. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27602928 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - van Iersel JJ AU - de Witte CJ AU - Verheijen PM AU - Broeders IA AU - Lenters E AU - Consten EC AU - Schraffordt Koops SE FA - van Iersel, Jan J FA - de Witte, Chris J FA - Verheijen, Paul M FA - Broeders, Ivo A M J FA - Lenters, Egbert FA - Consten, Esther C J FA - Schraffordt Koops, Steven E IN - van Iersel, Jan J. 1 Department of Surgery, Meander Medical Center, Amersfoort, the Netherlands 2 Faculty of Science and Technology, Institute of Technical Medicine, Twente University, Enschede, the Netherlands 3 Department of Gynecology, Meander Medical Center, Amersfoort, the Netherlands. TI - Robot-Assisted Sacrocolporectopexy for Multicompartment Prolapse of the Pelvic Floor: A Prospective Cohort Study Evaluating Functional and Sexual Outcome. SO - Diseases of the Colon & Rectum. 59(10):968-74, 2016 Oct AS - Dis Colon Rectum. 59(10):968-74, 2016 Oct NJ - Diseases of the colon and rectum PI - Journal available in: Print PI - Citation processed from: Internet JC - eab, 0372764 IO - Dis. Colon Rectum SB - Index Medicus CP - United States MH - Digestive System Surgical Procedures/ae [Adverse Effects] MH - Digestive System Surgical Procedures/is [Instrumentation] MH - Digestive System Surgical Procedures/mt [Methods] MH - *Digestive System Surgical Procedures MH - Female MH - Humans MH - Male MH - Middle Aged MH - Netherlands MH - Pelvic Floor/pp [Physiopathology] MH - *Pelvic Floor/su [Surgery] MH - Pelvic Organ Prolapse/di [Diagnosis] MH - Pelvic Organ Prolapse/pp [Physiopathology] MH - Pelvic Organ Prolapse/su [Surgery] MH - Postoperative Complications/di [Diagnosis] MH - Postoperative Complications/pp [Physiopathology] MH - Postoperative Complications/px [Psychology] MH - *Postoperative Complications MH - Prospective Studies MH - Quality of Life MH - Reconstructive Surgical Procedures/ae [Adverse Effects] MH - Reconstructive Surgical Procedures/is [Instrumentation] MH - Reconstructive Surgical Procedures/mt [Methods] MH - *Reconstructive Surgical Procedures MH - Recovery of Function MH - Rectal Prolapse/di [Diagnosis] MH - Rectal Prolapse/pp [Physiopathology] MH - Rectal Prolapse/su [Surgery] MH - *Rectal Prolapse MH - *Rectum/su [Surgery] MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - Robotic Surgical Procedures/is [Instrumentation] MH - Robotic Surgical Procedures/mt [Methods] MH - *Robotic Surgical Procedures MH - Sexual Behavior MH - Surgical Mesh MH - Surveys and Questionnaires MH - Treatment Outcome AB - BACKGROUND: Pelvic floor disorders are a major public health issue. For female genital prolapse, sacrocolpopexy is the gold standard. Laparoscopic ventral mesh rectopexy is a relatively new and promising technique correcting rectal prolapse. There is no literature combining the 2 robotically assisted techniques. AB - OBJECTIVE: This study was designed to evaluate the safety, quality of life, and functional and sexual outcomes of robot-assisted sacrocolporectopexy for multicompartment prolapse of the pelvic floor. AB - DESIGN: This was a prospective, observational cohort study. AB - SETTINGS: The study was conducted in a tertiary care setting. AB - PATIENTS: All sexually active patients undergoing robot-assisted sacrocolporectopexy at our institution between 2012 and 2014 were included. AB - INTERVENTION: Robot-assisted sacrocolporectopexy was the study intervention. AB - MAIN OUTCOME MEASURES: Preoperative and postoperative (12 months) questionnaires using the Urinary Distress Inventory, Pescatori Incontinence Scale, Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire, and Pelvic Floor Impact Questionnaire were completed. In addition Wexner and Vaizey incontinence scores and the Wexner constipation score were recorded postoperatively. AB - RESULTS: Fifty-one patients underwent robot-assisted sacrocolporectopexy (median follow-up, 12.5 months). The simplified Pelvic Organ Prolapse Quantification improved significantly (p < 0.0005) for all 4 of the anatomic landmarks. Both median fecal (preoperative and postoperative Pescatori 4 vs 3, p = 0.002) and urinary incontinence scores (Urinary Distress Inventory, 27.8 vs 22.2; p < 0.0005) improved significantly at 12 months. Postoperatively median Wexner (3) and Vaizey incontinence (6) and Wexner Constipation (7) scores were noted. A positive effect on sexual function (Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire score 31.8 vs 35.9; p = 0.002) and quality of life for each compartment (p < 0.0005) was observed. One patient (2%) developed mesh erosion. No multicompartment recurrences were detected. AB - LIMITATIONS: This was a observational study with a limited follow-up, no control group, and no preoperatively validated constipation score. AB - CONCLUSIONS: Robot-assisted sacrocolporectopexy is a safe and effective technique for multicompartment prolapse in terms of functional outcome, quality of life, and sexual function. ES - 1530-0358 IL - 0012-3706 DI - 00003453-201610000-00009 DO - https://dx.doi.org/10.1097/DCR.0000000000000669 PT - Journal Article PT - Observational Study ID - 10.1097/DCR.0000000000000669 [doi] ID - 00003453-201610000-00009 [pii] PP - ppublish LG - English DP - 2016 Oct DC - 20160908 EZ - 2016/09/08 06:00 DA - 2017/04/08 06:00 DT - 2016/09/08 06:00 YR - 2016 ED - 20170407 RD - 20170407 UP - 20170410 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=27602928 <6. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28183345 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Grochola LF AU - Soll C AU - Zehnder A AU - Wyss R AU - Herzog P AU - Breitenstein S AI - Breitenstein, Stefan; ORCID: http://orcid.org/0000-0002-9673-2788 FA - Grochola, Lukasz Filip FA - Soll, Christopher FA - Zehnder, Adrian FA - Wyss, Roland FA - Herzog, Pascal FA - Breitenstein, Stefan IN - Grochola, Lukasz Filip. Department of Surgery, Cantonal Hospital of Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland. IN - Soll, Christopher. Department of Surgery, Cantonal Hospital of Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland. IN - Zehnder, Adrian. Department of Surgery, Cantonal Hospital of Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland. IN - Wyss, Roland. Department of Surgery, Cantonal Hospital of Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland. IN - Herzog, Pascal. Department of Surgery, Cantonal Hospital of Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland. IN - Breitenstein, Stefan. Department of Surgery, Cantonal Hospital of Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland. stefan.breitenstein@ksw.ch. TI - Robot-assisted single-site compared with laparoscopic single-incision cholecystectomy for benign gallbladder disease: protocol for a randomized controlled trial. SO - BMC Surgery. 17(1):13, 2017 Feb 09 AS - BMC surg.. 17(1):13, 2017 Feb 09 NJ - BMC surgery PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 100968567 IO - BMC Surg SB - Index Medicus CP - England MH - Blood Loss, Surgical MH - *Cholecystectomy/mt [Methods] MH - *Cholecystectomy, Laparoscopic/mt [Methods] MH - *Gallbladder Diseases/su [Surgery] MH - Humans MH - Laparoscopy/mt [Methods] MH - Learning Curve MH - Length of Stay MH - Operative Time MH - Quality of Life MH - *Robotics/mt [Methods] MH - Single-Blind Method KW - *Cholecystectomy; *Robot-assisted laparoscopy; *Single Site; *Single incision; *Stress load; *Surgeon's Comfort; *da Vinci AB - BACKGROUND: Recent advances in robotic technology suggest that the utilization of the da Vinci Single-SiteTM platform for cholecystectomy is safe, feasible and results in a shorter learning curve compared to conventional single-incision laparoscopic cholecystectomy. Moreover, the robot-assisted technology has been shown to reduce the surgeon's stress load compared to standard single-incision laparoscopy in an experimental setup, suggesting an important advantage of the da Vinci platform. However, the above-mentioned observations are based solely on case series, case reports and experimental data, as high-quality clinical trials to demonstrate the benefits of the da Vinci Single-SiteTM cholecystectomy have not been performed to date. AB - METHODS: This study addresses the question whether robot-assisted Single-SiteTM cholecystectomy provides significant benefits over single-incision laparoscopic cholecystectomy in terms of surgeon's stress load, while matching the standards of the conventional single-incision approach with regard to peri- and postoperative outcomes. It is designed as a single centre, single-blinded randomized controlled trial, which compares both surgical approaches with the primary endpoint surgeon's physical and mental stress load at the time of surgery. In addition, the study aims to assess secondary endpoints such as operating time, conversion rates, additional trocar placement, intra-operative blood loss, length of hospital stay, costs of procedure, health-related quality of life, cosmesis and complications. Patients as well as ward staff are blinded until the 1^st postoperative year. Sample size calculation based on the results of a previously published experimental setup utilizing an estimated effect size of surgeon's comfort of 0.8 (power of 0.8, alpha-error level of 0.05, error margin of 10-15%) resulted in a number of 30 randomized patients per arm. AB - DISCUSSION: The study is the first randomized controlled trial that compares the da Vinci Single SiteTM platform to conventional laparoscopic approaches in cholecystectomy, one of the most frequently performed operations in general surgery. AB - TRIAL REGISTRATION: This trial is registered at clinicaltrials.gov (trial number: NCT02485392 ). Registered February 19, 2015. ES - 1471-2482 IL - 1471-2482 DI - 10.1186/s12893-017-0206-1 DO - https://dx.doi.org/10.1186/s12893-017-0206-1 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 10.1186/s12893-017-0206-1 [doi] ID - 10.1186/s12893-017-0206-1 [pii] PP - epublish PH - 2016/08/23 [received] PH - 2017/01/10 [accepted] LG - English EP - 20170209 DP - 2017 Feb 09 DC - 20170210 EZ - 2017/02/11 06:00 DA - 2017/04/05 06:00 DT - 2017/02/12 06:00 YR - 2017 ED - 20170404 RD - 20170404 UP - 20170406 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=28183345 <7. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27749475 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Schootman M AU - Hendren S AU - Ratnapradipa K AU - Stringer L AU - Davidson NO FA - Schootman, Mario FA - Hendren, Samantha FA - Ratnapradipa, Kendra FA - Stringer, Lisa FA - Davidson, Nick O IN - Schootman, Mario. 1 Department of Epidemiology, College for Public Health and Social Justice, St. Louis University, St. Louis, Missouri 2 Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine, St. Louis, Missouri 3 Department of Surgery, University of Michigan, Ann Arbor, Michigan 4 Department of Health Management and Policy, College for Public Health and Social Justice, St. Louis University, St. Louis, Missouri 5 Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri. TI - Adoption of Robotic Technology for Treating Colorectal Cancer. SO - Diseases of the Colon & Rectum. 59(11):1011-1018, 2016 Nov AS - Dis Colon Rectum. 59(11):1011-1018, 2016 Nov NJ - Diseases of the colon and rectum PI - Journal available in: Print PI - Citation processed from: Internet JC - eab, 0372764 IO - Dis. Colon Rectum SB - Index Medicus CP - United States MH - Colectomy/ae [Adverse Effects] MH - Colectomy/mt [Methods] MH - Colectomy/td [Trends] MH - *Colectomy MH - Colorectal Neoplasms/ep [Epidemiology] MH - Colorectal Neoplasms/su [Surgery] MH - *Colorectal Neoplasms MH - Cross-Sectional Studies MH - Delivery of Health Care/sn [Statistics & Numerical Data] MH - Female MH - Health Care Surveys MH - Hospitals/sn [Statistics & Numerical Data] MH - Hospitals/td [Trends] MH - *Hospitals MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/mt [Methods] MH - *Laparoscopy MH - Male MH - Middle Aged MH - Minimally Invasive Surgical Procedures/mt [Methods] MH - Neoplasm Staging MH - *Postoperative Complications/ep [Epidemiology] MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - Robotic Surgical Procedures/mt [Methods] MH - Robotic Surgical Procedures/td [Trends] MH - *Robotic Surgical Procedures MH - United States/ep [Epidemiology] AB - BACKGROUND: Debate exists regarding the role of robotic-assisted surgery in colorectal cancer. Robotic-assisted surgery has been promoted as a strategy to increase the availability of minimally invasive surgery, which is associated with improved short-term morbidity; however, robotic-assisted surgery is much more expensive than laparoscopic surgery. AB - OBJECTIVE: We aimed to understand hospital and patient trends in the adoption of robotic-assisted surgery. AB - DESIGN: The study used cross-sectional and longitudinal designs. AB - SETTINGS: The study included 2010 and 2012 American Hospital Association surveys, as well as the 2010-2012 Nationwide Inpatient Sample. AB - PATIENTS: US hospitals responding to the American Hospital Association survey were included to measure patients with colorectal cancer who were undergoing elective minimally invasive surgery or open resection. AB - MAIN OUTCOME MEASURES: Robotic-assisted surgery adoption by US hospitals was measured, regarding specifically patients with colorectal cancer who were treated with robotic surgery. AB - RESULTS: In 2010, 20.1% of hospitals adopted robotic-assisted surgery, increasing to 27.4% by 2012. Hospitals more likely to adopt robotic-assisted surgery included teaching hospitals, those with more advanced imaging services, those in metropolitan rather than rural areas, and those performing the highest inpatient surgery volume. Robotic-assisted surgery only accounted for 1.3% of colorectal cancer operations during 2010-2012, but patient probability of robotic-assisted surgery ranged from 0.1% to 15.2%. The percentage of patients with colorectal cancer who were treated robotically among those undergoing minimally invasive surgery increased over time (2010, 1.5%; 2012, 3.6%). Robotic-assisted surgery is increasing more rapidly for patients with rectal cancer with minimally invasive surgery (2010, 5.5%; 2012, 13.3%) versus patients with colon cancer treated with minimally invasive surgery (2010, 1.3%; 2012, 3.3%). AB - LIMITATIONS: The study was limited by its observational study design. AB - CONCLUSIONS: Robotic-assisted surgery uptake remains low for colon cancer but higher for rectal cancer surgery, suggesting a more thoughtful adoption of robotic-assisted surgery for colorectal cancer by focusing its use on more technically challenging cases. ES - 1530-0358 IL - 0012-3706 DI - 00003453-201611000-00002 DO - https://dx.doi.org/10.1097/DCR.0000000000000688 PT - Journal Article PT - Observational Study ID - 10.1097/DCR.0000000000000688 [doi] ID - 00003453-201611000-00002 [pii] PP - ppublish GI - No: R01 DK056260 Organization: (DK) *NIDDK NIH HHS* Country: United States No: R01 HL038180 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English DP - 2016 Nov DC - 20161017 EZ - 2016/10/18 06:00 DA - 2017/04/05 06:00 DT - 2016/10/18 06:00 YR - 2016 ED - 20170404 RD - 20170404 UP - 20170406 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=27749475 <8. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27749475 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Schootman M AU - Hendren S AU - Ratnapradipa K AU - Stringer L AU - Davidson NO FA - Schootman, Mario FA - Hendren, Samantha FA - Ratnapradipa, Kendra FA - Stringer, Lisa FA - Davidson, Nick O IN - Schootman, Mario. 1 Department of Epidemiology, College for Public Health and Social Justice, St. Louis University, St. Louis, Missouri 2 Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine, St. Louis, Missouri 3 Department of Surgery, University of Michigan, Ann Arbor, Michigan 4 Department of Health Management and Policy, College for Public Health and Social Justice, St. Louis University, St. Louis, Missouri 5 Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri. TI - Adoption of Robotic Technology for Treating Colorectal Cancer. SO - Diseases of the Colon & Rectum. 59(11):1011-1018, 2016 Nov AS - Dis Colon Rectum. 59(11):1011-1018, 2016 Nov NJ - Diseases of the colon and rectum PI - Journal available in: Print PI - Citation processed from: Internet JC - eab, 0372764 IO - Dis. Colon Rectum SB - Index Medicus CP - United States MH - Colectomy/ae [Adverse Effects] MH - Colectomy/mt [Methods] MH - Colectomy/td [Trends] MH - *Colectomy MH - Colorectal Neoplasms/ep [Epidemiology] MH - Colorectal Neoplasms/su [Surgery] MH - *Colorectal Neoplasms MH - Cross-Sectional Studies MH - Delivery of Health Care/sn [Statistics & Numerical Data] MH - Female MH - Health Care Surveys MH - Hospitals/sn [Statistics & Numerical Data] MH - Hospitals/td [Trends] MH - *Hospitals MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/mt [Methods] MH - *Laparoscopy MH - Male MH - Middle Aged MH - Minimally Invasive Surgical Procedures/mt [Methods] MH - Neoplasm Staging MH - *Postoperative Complications/ep [Epidemiology] MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - Robotic Surgical Procedures/mt [Methods] MH - Robotic Surgical Procedures/td [Trends] MH - *Robotic Surgical Procedures MH - United States/ep [Epidemiology] AB - BACKGROUND: Debate exists regarding the role of robotic-assisted surgery in colorectal cancer. Robotic-assisted surgery has been promoted as a strategy to increase the availability of minimally invasive surgery, which is associated with improved short-term morbidity; however, robotic-assisted surgery is much more expensive than laparoscopic surgery. AB - OBJECTIVE: We aimed to understand hospital and patient trends in the adoption of robotic-assisted surgery. AB - DESIGN: The study used cross-sectional and longitudinal designs. AB - SETTINGS: The study included 2010 and 2012 American Hospital Association surveys, as well as the 2010-2012 Nationwide Inpatient Sample. AB - PATIENTS: US hospitals responding to the American Hospital Association survey were included to measure patients with colorectal cancer who were undergoing elective minimally invasive surgery or open resection. AB - MAIN OUTCOME MEASURES: Robotic-assisted surgery adoption by US hospitals was measured, regarding specifically patients with colorectal cancer who were treated with robotic surgery. AB - RESULTS: In 2010, 20.1% of hospitals adopted robotic-assisted surgery, increasing to 27.4% by 2012. Hospitals more likely to adopt robotic-assisted surgery included teaching hospitals, those with more advanced imaging services, those in metropolitan rather than rural areas, and those performing the highest inpatient surgery volume. Robotic-assisted surgery only accounted for 1.3% of colorectal cancer operations during 2010-2012, but patient probability of robotic-assisted surgery ranged from 0.1% to 15.2%. The percentage of patients with colorectal cancer who were treated robotically among those undergoing minimally invasive surgery increased over time (2010, 1.5%; 2012, 3.6%). Robotic-assisted surgery is increasing more rapidly for patients with rectal cancer with minimally invasive surgery (2010, 5.5%; 2012, 13.3%) versus patients with colon cancer treated with minimally invasive surgery (2010, 1.3%; 2012, 3.3%). AB - LIMITATIONS: The study was limited by its observational study design. AB - CONCLUSIONS: Robotic-assisted surgery uptake remains low for colon cancer but higher for rectal cancer surgery, suggesting a more thoughtful adoption of robotic-assisted surgery for colorectal cancer by focusing its use on more technically challenging cases. ES - 1530-0358 IL - 0012-3706 DI - 00003453-201611000-00002 DO - https://dx.doi.org/10.1097/DCR.0000000000000688 PT - Journal Article PT - Observational Study ID - 10.1097/DCR.0000000000000688 [doi] ID - 00003453-201611000-00002 [pii] PP - ppublish GI - No: P30 CA091842 Organization: (CA) *NCI NIH HHS* Country: United States No: R01 DK056260 Organization: (DK) *NIDDK NIH HHS* Country: United States No: R01 HL038180 Organization: (HL) *NHLBI NIH HHS* Country: United States No: UL1 TR000448 Organization: (TR) *NCATS NIH HHS* Country: United States LG - English DP - 2016 Nov DC - 20161017 EZ - 2016/10/18 06:00 DA - 2017/04/05 06:00 DT - 2016/10/18 06:00 YR - 2016 ED - 20170404 RD - 20170420 UP - 20170421 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=27749475 <9. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28183345 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Grochola LF AU - Soll C AU - Zehnder A AU - Wyss R AU - Herzog P AU - Breitenstein S AI - Breitenstein, Stefan; ORCID: http://orcid.org/0000-0002-9673-2788 FA - Grochola, Lukasz Filip FA - Soll, Christopher FA - Zehnder, Adrian FA - Wyss, Roland FA - Herzog, Pascal FA - Breitenstein, Stefan IN - Grochola, Lukasz Filip. Department of Surgery, Cantonal Hospital of Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland. IN - Soll, Christopher. Department of Surgery, Cantonal Hospital of Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland. IN - Zehnder, Adrian. Department of Surgery, Cantonal Hospital of Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland. IN - Wyss, Roland. Department of Surgery, Cantonal Hospital of Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland. IN - Herzog, Pascal. Department of Surgery, Cantonal Hospital of Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland. IN - Breitenstein, Stefan. Department of Surgery, Cantonal Hospital of Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland. stefan.breitenstein@ksw.ch. TI - Robot-assisted single-site compared with laparoscopic single-incision cholecystectomy for benign gallbladder disease: protocol for a randomized controlled trial. SO - BMC Surgery. 17(1):13, 2017 Feb 09 AS - BMC surg.. 17(1):13, 2017 Feb 09 NJ - BMC surgery PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 100968567 IO - BMC Surg SB - Index Medicus CP - England MH - Blood Loss, Surgical MH - *Cholecystectomy/mt [Methods] MH - *Cholecystectomy, Laparoscopic/mt [Methods] MH - *Gallbladder Diseases/su [Surgery] MH - Humans MH - Laparoscopy/mt [Methods] MH - Learning Curve MH - Length of Stay MH - Operative Time MH - Quality of Life MH - *Robotics/mt [Methods] MH - Single-Blind Method KW - *Cholecystectomy; *Robot-assisted laparoscopy; *Single Site; *Single incision; *Stress load; *Surgeon's Comfort; *da Vinci AB - BACKGROUND: Recent advances in robotic technology suggest that the utilization of the da Vinci Single-SiteTM platform for cholecystectomy is safe, feasible and results in a shorter learning curve compared to conventional single-incision laparoscopic cholecystectomy. Moreover, the robot-assisted technology has been shown to reduce the surgeon's stress load compared to standard single-incision laparoscopy in an experimental setup, suggesting an important advantage of the da Vinci platform. However, the above-mentioned observations are based solely on case series, case reports and experimental data, as high-quality clinical trials to demonstrate the benefits of the da Vinci Single-SiteTM cholecystectomy have not been performed to date. AB - METHODS: This study addresses the question whether robot-assisted Single-SiteTM cholecystectomy provides significant benefits over single-incision laparoscopic cholecystectomy in terms of surgeon's stress load, while matching the standards of the conventional single-incision approach with regard to peri- and postoperative outcomes. It is designed as a single centre, single-blinded randomized controlled trial, which compares both surgical approaches with the primary endpoint surgeon's physical and mental stress load at the time of surgery. In addition, the study aims to assess secondary endpoints such as operating time, conversion rates, additional trocar placement, intra-operative blood loss, length of hospital stay, costs of procedure, health-related quality of life, cosmesis and complications. Patients as well as ward staff are blinded until the 1^st postoperative year. Sample size calculation based on the results of a previously published experimental setup utilizing an estimated effect size of surgeon's comfort of 0.8 (power of 0.8, alpha-error level of 0.05, error margin of 10-15%) resulted in a number of 30 randomized patients per arm. AB - DISCUSSION: The study is the first randomized controlled trial that compares the da Vinci Single SiteTM platform to conventional laparoscopic approaches in cholecystectomy, one of the most frequently performed operations in general surgery. AB - TRIAL REGISTRATION: This trial is registered at clinicaltrials.gov (trial number: NCT02485392 ). Registered February 19, 2015. ES - 1471-2482 IL - 1471-2482 DI - 10.1186/s12893-017-0206-1 DO - https://dx.doi.org/10.1186/s12893-017-0206-1 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 10.1186/s12893-017-0206-1 [doi] ID - 10.1186/s12893-017-0206-1 [pii] ID - PMC5301379 [pmc] PP - epublish PH - 2016/08/23 [received] PH - 2017/01/10 [accepted] LG - English EP - 20170209 DP - 2017 Feb 09 DC - 20170210 EZ - 2017/02/11 06:00 DA - 2017/04/05 06:00 DT - 2017/02/12 06:00 YR - 2017 ED - 20170404 RD - 20170410 UP - 20170411 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=28183345 <10. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27817158 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Elschot M AU - Selnaes KM AU - Sandsmark E AU - Kruger-Stokke B AU - Storkersen O AU - Tessem MB AU - Moestue SA AU - Bertilsson H AU - Bathen TF AI - Elschot, Mattijs; ORCID: http://orcid.org/0000-0002-8056-9103 FA - Elschot, Mattijs FA - Selnaes, Kirsten M FA - Sandsmark, Elise FA - Kruger-Stokke, Brage FA - Storkersen, Oystein FA - Tessem, May-Britt FA - Moestue, Siver A FA - Bertilsson, Helena FA - Bathen, Tone F IN - Elschot, Mattijs. Deparment of Circulation and Medical Imaging, Faculty of Medicine, NTNU, Norwegian University of Science and Technology, Mail MTFS*3.1313, POBox 8905, N-7491, Trondheim, Norway. mattijs.elschot@ntnu.no. IN - Selnaes, Kirsten M. Deparment of Circulation and Medical Imaging, Faculty of Medicine, NTNU, Norwegian University of Science and Technology, Mail MTFS*3.1313, POBox 8905, N-7491, Trondheim, Norway. IN - Selnaes, Kirsten M. St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway. IN - Sandsmark, Elise. Deparment of Circulation and Medical Imaging, Faculty of Medicine, NTNU, Norwegian University of Science and Technology, Mail MTFS*3.1313, POBox 8905, N-7491, Trondheim, Norway. IN - Kruger-Stokke, Brage. Deparment of Circulation and Medical Imaging, Faculty of Medicine, NTNU, Norwegian University of Science and Technology, Mail MTFS*3.1313, POBox 8905, N-7491, Trondheim, Norway. IN - Kruger-Stokke, Brage. Department of Radiology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway. IN - Storkersen, Oystein. Department of Pathology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway. IN - Tessem, May-Britt. Deparment of Circulation and Medical Imaging, Faculty of Medicine, NTNU, Norwegian University of Science and Technology, Mail MTFS*3.1313, POBox 8905, N-7491, Trondheim, Norway. IN - Moestue, Siver A. Deparment of Circulation and Medical Imaging, Faculty of Medicine, NTNU, Norwegian University of Science and Technology, Mail MTFS*3.1313, POBox 8905, N-7491, Trondheim, Norway. IN - Moestue, Siver A. Department of Laboratory Medicine, Children's and Women's Health, Faculty of Medicine, NTNU, Norwegian University of Science and Technology, Trondheim, Norway. IN - Bertilsson, Helena. Department of Urology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway. IN - Bertilsson, Helena. Department of Cancer Research and Molecular Medicine, Faculty of Medicine, NTNU, Norwegian University of Science and Technology, Trondheim, Norway. IN - Bathen, Tone F. Deparment of Circulation and Medical Imaging, Faculty of Medicine, NTNU, Norwegian University of Science and Technology, Mail MTFS*3.1313, POBox 8905, N-7491, Trondheim, Norway. IN - Bathen, Tone F. St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway. TI - A PET/MRI study towards finding the optimal [¹⁸F]Fluciclovine PET protocol for detection and characterisation of primary prostate cancer. SO - European Journal of Nuclear Medicine & Molecular Imaging. 44(4):695-703, 2017 Apr AS - Eur J Nucl Med Mol Imaging. 44(4):695-703, 2017 Apr NJ - European journal of nuclear medicine and molecular imaging PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101140988 IO - Eur. J. Nucl. Med. Mol. Imaging SB - Index Medicus CP - Germany MH - Aged MH - *Carboxylic Acids/ad [Administration & Dosage] MH - Carboxylic Acids/ae [Adverse Effects] MH - Carboxylic Acids/pk [Pharmacokinetics] MH - *Cyclobutanes/ad [Administration & Dosage] MH - Cyclobutanes/ae [Adverse Effects] MH - Cyclobutanes/pk [Pharmacokinetics] MH - Humans MH - Magnetic Resonance Imaging MH - Male MH - Middle Aged MH - Multimodal Imaging MH - *Positron-Emission Tomography MH - *Prostatic Neoplasms/dg [Diagnostic Imaging] MH - *Radiopharmaceuticals/ad [Administration & Dosage] MH - Radiopharmaceuticals/ae [Adverse Effects] MH - Radiopharmaceuticals/pk [Pharmacokinetics] MH - Sensitivity and Specificity KW - *Dynamic PET; *PET/MRI; *Prostate Cancer; *[18F]FACBC; *[18F]Fluciclovine AB - PURPOSE: [¹⁸F]Fluciclovine PET imaging shows promise for the assessment of prostate cancer. The purpose of this PET/MRI study is to optimise the PET imaging protocol for detection and characterisation of primary prostate cancer, by quantitative evaluation of the dynamic uptake of [¹⁸F]Fluciclovine in cancerous and benign tissue. AB - METHODS: Patients diagnosed with high-risk primary prostate cancer underwent an integrated [¹⁸F]Fluciclovine PET/MRI exam before robot-assisted radical prostatectomy with extended pelvic lymph node dissection. Volumes-of-interest (VOIs) of selected organs (prostate, bladder, blood pool) and sub-glandular prostate structures (tumour, benign prostatic hyperplasia (BPH), inflammation, healthy tissue) were delineated on T2-weighted MR images, using whole-mount histology samples as a reference. Three candidate windows for optimal PET imaging were identified based on the dynamic curves of the mean and maximum standardised uptake value (SUV_mean and SUV_max, respectively). The statistical significance of differences in SUV between VOIs were analysed using Wilcoxon rank sum tests (p<0.05, adjusted for multiple testing). AB - RESULTS: Twenty-eight (28) patients [median (range) age: 66 (55-72) years] were included. An early (W1: 5-10 minutes post-injection) and two late candidate windows (W2: 18-23; W3: 33-38 minutes post-injection) were selected. Late compared with early imaging was better able to distinguish between malignant and benign tissue [W3, SUV_mean: tumour vs. BPH 2.5 vs. 2.0 (p<0.001), tumour vs. inflammation 2.5 vs. 1.7 (p<0.001), tumour vs. healthy tissue 2.5 vs. 2.0 (p<0.001); W1, SUV_mean: tumour vs. BPH 3.1 vs. 3.1 (p=0.771), tumour vs inflammation 3.1 vs. 2.2 (p=0.021), tumour vs. healthy tissue 3.1 vs. 2.5 (p<0.001)] as well as between high-grade and low/intermediate-grade tumours (W3, SUV_mean: 2.6 vs. 2.1 (p=0.040); W1, SUV_mean: 3.1 vs. 2.8 (p=0.173)). These differences were relevant to the peripheral zone, but not the central gland. AB - CONCLUSION: Late-window [¹⁸F]Fluciclovine PET imaging shows promise for distinguishing between prostate tumours and benign tissue and for assessment of tumour aggressiveness. RN - 0 (Carboxylic Acids) RN - 0 (Cyclobutanes) RN - 0 (Radiopharmaceuticals) RN - 38R1Q0L1ZE (fluciclovine F-18) ES - 1619-7089 IL - 1619-7070 DI - 10.1007/s00259-016-3562-7 DO - https://dx.doi.org/10.1007/s00259-016-3562-7 PT - Clinical Trial PT - Journal Article ID - 10.1007/s00259-016-3562-7 [doi] ID - 10.1007/s00259-016-3562-7 [pii] PP - ppublish PH - 2016/06/23 [received] PH - 2016/10/25 [accepted] LG - English EP - 20161105 DP - 2017 Apr DC - 20161106 EZ - 2016/11/07 06:00 DA - 2017/03/14 06:00 DT - 2016/11/07 06:00 YR - 2017 ED - 20170313 RD - 20170313 UP - 20170315 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=27817158 <11. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27531014 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Angenete E AU - Angeras U AU - Borjesson M AU - Ekelund J AU - Gellerstedt M AU - Thorsteinsdottir T AU - Steineck G AU - Haglind E FA - Angenete, E FA - Angeras, U FA - Borjesson, M FA - Ekelund, J FA - Gellerstedt, M FA - Thorsteinsdottir, T FA - Steineck, G FA - Haglind, E IN - Angenete, E. Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, SSORG, Sahlgrenska University Hospital/Ostra, SE-416 85, Gothenburg, Sweden. eva.angenete@vgregion.se. IN - Angeras, U. Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, SSORG, Sahlgrenska University Hospital/Ostra, SE-416 85, Gothenburg, Sweden. IN - Borjesson, M. Swedish School of Sport and Health Sciences, Stockholm, Sweden. IN - Borjesson, M. Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden. IN - Ekelund, J. Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, SSORG, Sahlgrenska University Hospital/Ostra, SE-416 85, Gothenburg, Sweden. IN - Gellerstedt, M. University West, Trollhattan, Sweden. IN - Thorsteinsdottir, T. Faculty of Nursing, School of Health Sciences, University of Iceland, Reykjavik, Iceland. IN - Steineck, G. Division of Clinical Cancer Epidemiology, Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden. IN - Steineck, G. Department of Oncology and Pathology, Division of Clinical Cancer Epidemiology, Karolinska Institutet, Solna, Sweden. IN - Haglind, E. Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, SSORG, Sahlgrenska University Hospital/Ostra, SE-416 85, Gothenburg, Sweden. TI - Physical activity before radical prostatectomy reduces sick leave after surgery - results from a prospective, non-randomized controlled clinical trial (LAPPRO). SO - BMC Urology. 16(1):50, 2016 Aug 16 AS - BMC Urol. 16(1):50, 2016 Aug 16 NJ - BMC urology PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 100968571 IO - BMC Urol PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986175 SB - Index Medicus CP - England MH - Adult MH - *Exercise MH - Humans MH - *Length of Stay/sn [Statistics & Numerical Data] MH - Male MH - Middle Aged MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - *Sick Leave/sn [Statistics & Numerical Data] KW - *Physical fitness; *Prostatectomy; *Prostatic neoplasm AB - BACKGROUND: Studies have reported that early physical rehabilitation after surgical procedures is associated with improved outcome measured as shorter hospital stay and enhanced recovery. The aim of this study was to explore the relationship between the preoperative physical activity level and subsequent postoperative complications, sick-leave and hospital stay after radical prostatectomy for prostate cancer in the setting of the LAPPRO trial (LAParoscopic Prostatectomy Robot Open). AB - METHODS: LAPPRO is a prospective controlled trial, comparing robot-assisted laparoscopic and open surgery for localized prostate cancer between 2008 and 2011. 1569 patients aged 64 or less with an occupation were included in this sub-study. The Gleason score was <7 in 52 % of the patients. Demographics and the level of self-assessed preoperative physical activity, length of hospital stay, complications, quality of life, recovery and sick-leave were extracted from clinical record forms and questionnaires. Multivariable logistic regression, with log-link and logit-link functions, was used to adjust for potential confounding variables. AB - RESULTS: The patients were divided into four groups based on their level of activity. As the group with lowest engagement of physical activity was found to be significantly different in base line characteristics from the other groups they were excluded from further analysis. Among patients that were physically active preoperativelly (n=1467) there was no significant difference between the physical activity-groups regarding hospital stay, recovery or complications. However, in the group with the highest self-assessed level of physical activity, 5-7 times per week, 13 % required no sick leave, compared to 6.3 % in the group with a physical activity level of 1-2 times per week only (p<0.0001). AB - CONCLUSIONS: In our study of med operated with radical prostatectomy, a high level of physical activity preoperatively was associated with reduced need for sick leave after radical prostatectomy compared to men with lower physical activity. AB - TRIAL REGISTRATION: The trial is registered at the ISCRTN register. ISRCTN06393679 . ES - 1471-2490 IL - 1471-2490 DI - 10.1186/s12894-016-0168-0 DO - https://dx.doi.org/10.1186/s12894-016-0168-0 PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article PT - Multicenter Study ID - 27531014 [pubmed] ID - 10.1186/s12894-016-0168-0 [doi] ID - 10.1186/s12894-016-0168-0 [pii] ID - PMC4986175 [pmc] PP - epublish PH - 2015/01/28 [received] PH - 2016/08/08 [accepted] LG - English EP - 20160816 DP - 2016 Aug 16 DC - 20160817 EZ - 2016/08/18 06:00 DA - 2017/02/28 06:00 DT - 2016/08/18 06:00 YR - 2016 ED - 20170227 RD - 20170227 UP - 20170301 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=27531014 <12. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27749525 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bianchi R AU - Cozzi G AU - Petralia G AU - Alessi S AU - Renne G AU - Bottero D AU - Brescia A AU - Cioffi A AU - Cordima G AU - Ferro M AU - Matei DV AU - Mazzoleni F AU - Musi G AU - Mistretta FA AU - Serino A AU - Tringali VM AU - Coman I AU - De Cobelli O FA - Bianchi, Roberto FA - Cozzi, Gabriele FA - Petralia, Giuseppe FA - Alessi, Sarah FA - Renne, Giuseppe FA - Bottero, Danilo FA - Brescia, Antonio FA - Cioffi, Antonio FA - Cordima, Giovanni FA - Ferro, Matteo FA - Matei, Deliu Victor FA - Mazzoleni, Federica FA - Musi, Gennaro FA - Mistretta, Francesco Alessandro FA - Serino, Alessandro FA - Tringali, Valeria Maria Lucia FA - Coman, Ioan FA - De Cobelli, Ottavio IN - Bianchi, Roberto. aDivision of Urology bDivision of Radiology cDivision of Pathology, European Institute of Oncology dUniversita degli Studi di Milano, Milan, Italy eDepartment of Urology "Iuliu Hatieganu," University of Medicine and Pharmacy, Cluj-Napoca, Romania. TI - Multiparametric magnetic resonance imaging and frozen-section analysis efficiently predict upgrading, upstaging, and extraprostatic extension in patients undergoing nerve-sparing robotic-assisted radical prostatectomy. SO - Medicine. 95(40):e4519, 2016 Oct AS - Medicine (Baltimore). 95(40):e4519, 2016 Oct NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - *Frozen Sections MH - Humans MH - *Magnetic Resonance Imaging MH - Male MH - Margins of Excision MH - Middle Aged MH - Neoplasm Grading MH - Neoplasm Staging MH - Predictive Value of Tests MH - *Prostatectomy MH - *Prostatic Neoplasms/dg [Diagnostic Imaging] MH - *Prostatic Neoplasms/pa [Pathology] MH - Prostatic Neoplasms/su [Surgery] MH - Retrospective Studies MH - *Robotic Surgical Procedures AB - To evaluate the role of multiparametric magnetic resonance imaging (mpMRI) in predicting upgrading, upstaging, and extraprostatic extension in patients with low-risk prostate cancer (PCa). MpMRI may reduce positive surgical margins (PSM) and improve nerve-sparing during robotic-assisted radical prostatectomy (RARP) for localized prostate cancer PCa.This was a retrospective, monocentric, observational study. We retrieved the records of patients undergoing RARP from January 2012 to December 2013 at our Institution. Inclusion criteria were: PSA <10 ng/mL; clinical stage VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27749525 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bianchi R AU - Cozzi G AU - Petralia G AU - Alessi S AU - Renne G AU - Bottero D AU - Brescia A AU - Cioffi A AU - Cordima G AU - Ferro M AU - Matei DV AU - Mazzoleni F AU - Musi G AU - Mistretta FA AU - Serino A AU - Tringali VM AU - Coman I AU - De Cobelli O FA - Bianchi, Roberto FA - Cozzi, Gabriele FA - Petralia, Giuseppe FA - Alessi, Sarah FA - Renne, Giuseppe FA - Bottero, Danilo FA - Brescia, Antonio FA - Cioffi, Antonio FA - Cordima, Giovanni FA - Ferro, Matteo FA - Matei, Deliu Victor FA - Mazzoleni, Federica FA - Musi, Gennaro FA - Mistretta, Francesco Alessandro FA - Serino, Alessandro FA - Tringali, Valeria Maria Lucia FA - Coman, Ioan FA - De Cobelli, Ottavio IN - Bianchi, Roberto. aDivision of Urology bDivision of Radiology cDivision of Pathology, European Institute of Oncology dUniversita degli Studi di Milano, Milan, Italy eDepartment of Urology "Iuliu Hatieganu," University of Medicine and Pharmacy, Cluj-Napoca, Romania. TI - Multiparametric magnetic resonance imaging and frozen-section analysis efficiently predict upgrading, upstaging, and extraprostatic extension in patients undergoing nerve-sparing robotic-assisted radical prostatectomy. SO - Medicine. 95(40):e4519, 2016 Oct AS - Medicine (Baltimore). 95(40):e4519, 2016 Oct NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - *Frozen Sections MH - Humans MH - *Magnetic Resonance Imaging MH - Male MH - Margins of Excision MH - Middle Aged MH - Neoplasm Grading MH - Neoplasm Staging MH - Predictive Value of Tests MH - *Prostatectomy MH - *Prostatic Neoplasms/dg [Diagnostic Imaging] MH - *Prostatic Neoplasms/pa [Pathology] MH - Prostatic Neoplasms/su [Surgery] MH - Retrospective Studies MH - *Robotic Surgical Procedures AB - To evaluate the role of multiparametric magnetic resonance imaging (mpMRI) in predicting upgrading, upstaging, and extraprostatic extension in patients with low-risk prostate cancer (PCa). MpMRI may reduce positive surgical margins (PSM) and improve nerve-sparing during robotic-assisted radical prostatectomy (RARP) for localized prostate cancer PCa.This was a retrospective, monocentric, observational study. We retrieved the records of patients undergoing RARP from January 2012 to December 2013 at our Institution. Inclusion criteria were: PSA <10 ng/mL; clinical stage VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27741101 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Park JH AU - Cho S AU - Choi YS AU - Seo SK AU - Lee BS FA - Park, Joo Hyun FA - Cho, SiHyun FA - Choi, Young Sik FA - Seo, Seok Kyo FA - Lee, Byung Seok IN - Park, Joo Hyun. aDepartment of Obstetrics and Gynecology, Gangnam Severance Hospital bDepartment of Obstetrics and Gynecology, Severance Hospital cInstitute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, South Korea. TI - Robot-assisted segmental resection of tubal pregnancy followed by end-to-end reanastomosis for preserving tubal patency and fertility: An initial report. SO - Medicine. 95(41):e4714, 2016 Oct AS - Medicine (Baltimore). 95(41):e4714, 2016 Oct NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - *Fallopian Tubes/su [Surgery] MH - Female MH - *Fertility MH - Follow-Up Studies MH - Humans MH - Pregnancy MH - Pregnancy Outcome MH - Pregnancy Rate/td [Trends] MH - *Pregnancy, Tubal/su [Surgery] MH - Reproducibility of Results MH - Retrospective Studies MH - *Robotics/mt [Methods] MH - *Sterilization Reversal/mt [Methods] MH - Time Factors MH - Young Adult AB - The objective of this study was to evaluate whether robotic tubal reanastomosis after segmental resection of tubal pregnancy is a feasible means of preserving tubal integrity and natural fertility in those with compromised contralateral tubal condition.The study was performed at a university medical center in a retrospective manner where da Vinci robotic system-guided segmental resection of tubal ectopic mass followed by reanastomosis was performed to salvage tubal patency and fertility in those with a single viable fallopian tube. Of the 17 patients with tubal pregnancies that were selected, 14 patients with successful tubal segmental resection and reanastomosis were followed up. The reproducibility of anastomosis success and cumulative pregnancy rates of up to 24 months were analyzed.Patient mean age was 28.88 +/- 4.74 years, mean amenorrheic period was 7.01 +/- 1.57 weeks and mean human chorionic gonadotropin (hCG) level was 9289.00 +/- 7510.00 mIU/mL. The overall intraoperative cancellation rate due to unfavorable positioning or size of the tubal mass was 17.65% (3/17), which was converted to either salpingectomy or milking of ectopic mass. Of the 14 attempted, anastomosis for all 14 cases was successful, with 1 anastomotic leakage. One patient wishing to postpone pregnancy and 2 patients where patency of the contralateral tube was confirmed during the operation, were excluded from the pregnancy outcome analysis. Cumulative pregnancy rate was 63.64% (7/11), with 3 (27.27%) ongoing pregnancies, 3 (27.27%) livebirths, and 1 missed abortion at 24 months. During the follow-up, hysterosalpingography (HSG) was performed at 6 months for those who consented, and all 10 fallopian tubes tested were patent. No subsequent tubal pregnancies occurred in the reananstomosed tube for up to a period 24 months.For patients with absent or defective contralateral tubal function, da Vinci-guided reanastomosis after segmental resection of tubal pregnancy is feasible for salvaging tubal patency and fertility. ES - 1536-5964 IL - 0025-7974 DI - 00005792-201610110-00005 DO - https://dx.doi.org/10.1097/MD.0000000000004714 PT - Journal Article PT - Observational Study ID - 27741101 [pubmed] ID - 10.1097/MD.0000000000004714 [doi] ID - 00005792-201610110-00005 [pii] ID - PMC5072928 [pmc] PP - ppublish LG - English DP - 2016 Oct DC - 20161014 EZ - 2016/10/15 06:00 DA - 2017/02/15 06:00 DT - 2016/10/16 06:00 YR - 2016 ED - 20170214 RD - 20170214 UP - 20170216 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=27741101 <15. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27741101 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Park JH AU - Cho S AU - Choi YS AU - Seo SK AU - Lee BS FA - Park, Joo Hyun FA - Cho, SiHyun FA - Choi, Young Sik FA - Seo, Seok Kyo FA - Lee, Byung Seok IN - Park, Joo Hyun. aDepartment of Obstetrics and Gynecology, Gangnam Severance Hospital bDepartment of Obstetrics and Gynecology, Severance Hospital cInstitute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, South Korea. TI - Robot-assisted segmental resection of tubal pregnancy followed by end-to-end reanastomosis for preserving tubal patency and fertility: An initial report. SO - Medicine. 95(41):e4714, 2016 Oct AS - Medicine (Baltimore). 95(41):e4714, 2016 Oct NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - *Fallopian Tubes/su [Surgery] MH - Female MH - *Fertility MH - Follow-Up Studies MH - Humans MH - Pregnancy MH - Pregnancy Outcome MH - Pregnancy Rate/td [Trends] MH - *Pregnancy, Tubal/su [Surgery] MH - Reproducibility of Results MH - Retrospective Studies MH - *Robotics/mt [Methods] MH - *Sterilization Reversal/mt [Methods] MH - Time Factors MH - Young Adult AB - The objective of this study was to evaluate whether robotic tubal reanastomosis after segmental resection of tubal pregnancy is a feasible means of preserving tubal integrity and natural fertility in those with compromised contralateral tubal condition.The study was performed at a university medical center in a retrospective manner where da Vinci robotic system-guided segmental resection of tubal ectopic mass followed by reanastomosis was performed to salvage tubal patency and fertility in those with a single viable fallopian tube. Of the 17 patients with tubal pregnancies that were selected, 14 patients with successful tubal segmental resection and reanastomosis were followed up. The reproducibility of anastomosis success and cumulative pregnancy rates of up to 24 months were analyzed.Patient mean age was 28.88 +/- 4.74 years, mean amenorrheic period was 7.01 +/- 1.57 weeks and mean human chorionic gonadotropin (hCG) level was 9289.00 +/- 7510.00 mIU/mL. The overall intraoperative cancellation rate due to unfavorable positioning or size of the tubal mass was 17.65% (3/17), which was converted to either salpingectomy or milking of ectopic mass. Of the 14 attempted, anastomosis for all 14 cases was successful, with 1 anastomotic leakage. One patient wishing to postpone pregnancy and 2 patients where patency of the contralateral tube was confirmed during the operation, were excluded from the pregnancy outcome analysis. Cumulative pregnancy rate was 63.64% (7/11), with 3 (27.27%) ongoing pregnancies, 3 (27.27%) livebirths, and 1 missed abortion at 24 months. During the follow-up, hysterosalpingography (HSG) was performed at 6 months for those who consented, and all 10 fallopian tubes tested were patent. No subsequent tubal pregnancies occurred in the reananstomosed tube for up to a period 24 months.For patients with absent or defective contralateral tubal function, da Vinci-guided reanastomosis after segmental resection of tubal pregnancy is feasible for salvaging tubal patency and fertility. CI - The authors report no conflicts of interest. ES - 1536-5964 IL - 0025-7974 DI - 00005792-201610110-00005 DO - https://dx.doi.org/10.1097/MD.0000000000004714 PT - Journal Article PT - Observational Study ID - 27741101 [pubmed] ID - 10.1097/MD.0000000000004714 [doi] ID - 00005792-201610110-00005 [pii] ID - PMC5072928 [pmc] PP - ppublish LG - English DP - 2016 Oct DC - 20161014 EZ - 2016/10/15 06:00 DA - 2017/02/15 06:00 DT - 2016/10/16 06:00 YR - 2016 ED - 20170214 RD - 20170224 UP - 20170228 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=27741101 <16. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27175685 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kim NY AU - Han DW AU - Koh JC AU - Rha KH AU - Hong JH AU - Park JM AU - Kim SY FA - Kim, Na Young FA - Han, Dong Woo FA - Koh, Jae Chul FA - Rha, Koon Ho FA - Hong, Jung Hwa FA - Park, Jong Min FA - Kim, So Yeon IN - Kim, Na Young. From the Department of Anesthesiology and Pain Medicine (NYK, DWH, JCK, JMP, SYK); Anesthesia and Pain Research Institute (NYK, DWH, JCK, SYK); Department of Urology, Urological Science Institute (KHR); Department of Research Affairs, Biostatistics Collaboration Units (JHH), Yonsei University College of Medicine, Seoul, Republic of Korea. TI - Effect of Dexmedetomidine on Heart Rate-Corrected QT and Tpeak-Tend Intervals During Robot-Assisted Laparoscopic Prostatectomy With Steep Trendelenburg Position: A Prospective, Randomized, Double-Blinded, Controlled Study. SO - Medicine. 95(19):e3645, 2016 May AS - Medicine (Baltimore). 95(19):e3645, 2016 May NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902527 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - *Dexmedetomidine/pd [Pharmacology] MH - Double-Blind Method MH - Head-Down Tilt MH - *Heart Conduction System/de [Drug Effects] MH - *Heart Rate/de [Drug Effects] MH - Humans MH - *Hypnotics and Sedatives/pd [Pharmacology] MH - Intraoperative Care/mt [Methods] MH - Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - Robotic Surgical Procedures/mt [Methods] AB - Intraperitoneal insufflation of carbon dioxide may affect the sympathetic activity that leads to changes in ventricular repolarization. This in turn can result in changes of heart rate-corrected QT (QTc) interval and Tpeak-Tend (Tp-e) interval. Dexmedetomidine is a highly selective alpha2-receptor agonist and has potential antiarrhythmic properties. This prospective, randomized, double-blinded, controlled study evaluated the effects of dexmedetomidine administration on QTc and Tp-e intervals during robot-assisted laparoscopic prostatectomy with steep Trendelenburg position.Fifty patients scheduled for robot-assisted laparoscopic prostatectomy randomly received either a continuous infusion of dexmedetomidine at a rate of 0.3 mug/kg/hour, from anesthetic induction until the end of the Trendelenburg position (dexmedetomidine group; n = 25), or the same volume of normal saline (control group; n = 25). Anesthesia was maintained with sevoflurane and remifentanil. The primary and secondary goals were to evaluate the effect of dexmedetomidine on the QTc and Tp-e interval changes. Mean arterial pressure, heart rate, end-tidal CO2, and end-tidal sevoflurane concentrations were assessed as well.Forty-seven patients (94%) completed the study. Dexmedetomidine significantly attenuated QTc interval prolongation and reduced the Tp-e interval, even though the baseline values of the QTc and Tp-e intervals were similar between the 2 groups (PGroup x Time = 0.001 and 0.014, respectively). Twenty-two patients (96%) in the control group and 13 (54%) in the dexmedetomidine group had QTc interval prolongation of >20 ms from the baseline value during surgery (P = 0.001). The maximum QTc interval prolongation from the baseline value during surgery was 46 +/- 21 ms in the control group and 24 +/- 21 ms in the dexmedetomidine group (mean +/- SD, P = 0.001). Mean arterial pressure and heart rate were comparable between the groups.Continuous infusion of dexmedetomidine at a rate of 0.3 mug/kg/hour significantly attenuated the QTc interval prolongation induced by CO2 pneumoperitoneum with steep Trendelenburg position. Furthermore, dexmedetomidine reduced the Tp-e interval. Thus, dexmedetomidine administration may be effective for patients who are susceptible to the development of ventricular arrhythmia during robot-assisted laparoscopic prostatectomy. RN - 0 (Hypnotics and Sedatives) RN - 67VB76HONO (Dexmedetomidine) ES - 1536-5964 IL - 0025-7974 DI - 00005792-201605100-00064 DO - https://dx.doi.org/10.1097/MD.0000000000003645 PT - Journal Article PT - Randomized Controlled Trial ID - 27175685 [pubmed] ID - 10.1097/MD.0000000000003645 [doi] ID - 00005792-201605100-00064 [pii] ID - PMC4902527 [pmc] PP - ppublish LG - English DP - 2016 May DC - 20160514 EZ - 2016/05/14 06:00 DA - 2017/02/10 06:00 DT - 2016/05/14 06:00 YR - 2016 ED - 20170209 RD - 20170209 UP - 20170213 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=27175685 <17. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27613357 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Krane LS AU - Peyton CC AU - Olympio MA AU - Hemal AK FA - Krane, Louis S FA - Peyton, Charles C FA - Olympio, Michael A FA - Hemal, Ashok K IN - Krane, Louis S. Department of Urology, Wake Forest Baptist Health, Winston Salem, North Carolina. IN - Peyton, Charles C. Department of Urology, Wake Forest Baptist Health, Winston Salem, North Carolina. IN - Olympio, Michael A. Department of Urology, Wake Forest Baptist Health, Winston Salem, North Carolina. IN - Hemal, Ashok K. Department of Urology, Wake Forest Baptist Health, Winston Salem, North Carolina. ahemal@wakehealth.edu. TI - A randomized double blinded placebo controlled trial of sildenafil for renoprotection prior to hilar clamping in patients undergoing robotic assisted laparoscopic partial nephrectomy. SO - Journal of Surgical Oncology. 114(7):785-788, 2016 Dec AS - J Surg Oncol. 114(7):785-788, 2016 Dec NJ - Journal of surgical oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - k79, 0222643 IO - J Surg Oncol SB - Index Medicus CP - United States MH - Acute Kidney Injury/di [Diagnosis] MH - Acute Kidney Injury/et [Etiology] MH - *Acute Kidney Injury/pc [Prevention & Control] MH - Administration, Oral MH - Adult MH - Aged MH - Double-Blind Method MH - Drug Administration Schedule MH - Female MH - Follow-Up Studies MH - *Hemostasis, Surgical/ae [Adverse Effects] MH - Hemostasis, Surgical/mt [Methods] MH - Humans MH - Laparoscopy MH - Male MH - Middle Aged MH - Nephrectomy/mt [Methods] MH - *Nephrectomy MH - *Phosphodiesterase 5 Inhibitors/tu [Therapeutic Use] MH - Postoperative Complications/di [Diagnosis] MH - Postoperative Complications/et [Etiology] MH - *Postoperative Complications/pc [Prevention & Control] MH - Preoperative Care MH - Prospective Studies MH - Protective Agents/tu [Therapeutic Use] MH - Reperfusion Injury/di [Diagnosis] MH - Reperfusion Injury/et [Etiology] MH - *Reperfusion Injury/pc [Prevention & Control] MH - Robotic Surgical Procedures MH - *Sildenafil Citrate/tu [Therapeutic Use] MH - Treatment Outcome KW - acute kidney injury; ischemia; kidney; partial nephrectomy; phosphodiesterase inhibitor; robotic AB - OBJECTIVE: To perform a randomized control trial (RCT) assessing the effect of phosphodiesterase 5 inhibitor (PDE5i) used prior to hilar clamping during robot assisted partial nephrectomy (RAPN) for renoprotection. AB - MATERIALS AND METHODS: We performed an institutional review board approved, placebo controlled, double blinded RCT evaluating a single 100mg oral dose of sildenafil immediately prior to RAPN. Primary end point was accrual, participation and retention of patients with secondary endpoints assessing post-operative renal functional outcomes and safety. Exclusion criteria included history of coronary artery disease, solitary kidney, suspected benign pathology, PDE5i intolerance or pregnant females. AB - RESULTS: Of 40 eligible consecutive patients undergoing RPN between 9/2013 and 12/2014, 30 (75%) were randomized to treatment and there was 100% participation and retention. The groups were well matched for all measured comorbidities. Intraoperative outcomes including warm ischemia time (median 15 vs. 16.5min, P=0.29) were similar. Change in eGFR demonstrated similar decrease between sildenafil versus placebo at 1 day (-8% vs. -10%, P=0.53), 2 days (-9% vs. -9%, P=0.77), and 1 month (-4% vs. -6%, P=0.31) following RAPN. Intermediate follow up (median 183 days) demonstrated similar results (-8% vs. -1%, P=0.16) between the two cohorts. Safety profiles were similar between the two cohorts without any adverse reactions to the sildenafil. AB - CONCLUSIONS: Successful retention of patients was achieved in this RCT. The secondary outcome of renoprotection was not identified. J. Surg. Oncol. 2016;114:785-788. © 2016 2016 Wiley Periodicals, Inc. AB - Copyright © 2016 Wiley Periodicals, Inc. RN - 0 (Phosphodiesterase 5 Inhibitors) RN - 0 (Protective Agents) RN - BW9B0ZE037 (Sildenafil Citrate) ES - 1096-9098 IL - 0022-4790 DO - https://dx.doi.org/10.1002/jso.24419 PT - Journal Article PT - Randomized Controlled Trial ID - 27613357 [pubmed] ID - 10.1002/jso.24419 [doi] PP - ppublish PH - 2016/03/15 [received] PH - 2016/08/01 [accepted] LG - English EP - 20160909 DP - 2016 Dec DC - 20160910 EZ - 2016/09/11 06:00 DA - 2017/02/10 06:00 DT - 2016/10/30 06:00 YR - 2016 ED - 20170209 RD - 20170209 UP - 20170213 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=27613357 <18. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27495072 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kim JS AU - Choi JB AU - Lee SY AU - Kim WH AU - Baek NH AU - Kim J AU - Park CK AU - Lee YJ AU - Park SY FA - Kim, Jin Soo FA - Choi, Jong Bum FA - Lee, Sook Young FA - Kim, Wook Hwan FA - Baek, Nam Hyun FA - Kim, Jayoun FA - Park, Chu Kyung FA - Lee, Yeon Ju FA - Park, Sung Yong IN - Kim, Jin Soo. aDepartment of Anesthesiology and Pain Medicine bDepartment of Surgery cOffice of Biostatistics, Ajou University, School of Medicine, Suwon, Korea. TI - Pain related to robotic cholecystectomy with lower abdominal ports: effect of the bilateral ultrasound-guided split injection technique of rectus sheath block in female patients: A prospective randomised trial. SO - Medicine. 95(31):e4445, 2016 Aug AS - Medicine (Baltimore). 95(31):e4445, 2016 Aug NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979826 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Anesthetics, Local/ad [Administration & Dosage] MH - Cholecystectomy, Laparoscopic/ae [Adverse Effects] MH - *Cholecystectomy, Laparoscopic/mt [Methods] MH - Female MH - Follow-Up Studies MH - Humans MH - Middle Aged MH - *Nerve Block/mt [Methods] MH - Pain Measurement MH - *Pain, Postoperative/pc [Prevention & Control] MH - Prospective Studies MH - *Rectus Abdominis/de [Drug Effects] MH - Risk Assessment MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures/mt [Methods] MH - Robotics MH - Single-Blind Method MH - Treatment Outcome MH - *Ultrasonography, Interventional/mt [Methods] AB - BACKGROUND: Robotic cholecystectomy (RC) using port sites in the lower abdominal area (T12-L1) rather than the upper abdomen has recently been introduced as an alternative procedure for laparoscopic cholecystectomy. Therefore, we investigated the time course of different components of pain and the analgesic effect of the bilateral ultrasound-guided split injection technique for rectus sheath block (sRSB) after RC in female patients. AB - METHODS: We randomly assigned 40 patients to undergo ultrasound-guided sRSB (RSB group, n = 20) or to not undergo any block (control group, n = 20). Pain was subdivided into 3 components: superficial wound pain, deep abdominal pain, and referred shoulder pain, which were evaluated with a numeric rating scale (from 0 to 10) at baseline (time of awakening) and at 1, 6, 9, and 24 hours postoperatively. Consumption of fentanyl and general satisfaction were also evaluated 1 hour (before discharge from the postanesthesia care unit) and 24 hours postoperatively (end of study). AB - RESULTS: Superficial wound pain was predominant only at awakening, and after postoperative 1 hour in the control group. Bilateral ultrasound-guided sRSB significantly decreased superficial pain after RC (P < 0.01) and resulted in a better satisfaction score (P < 0.05) 1 hour after RC in the RSB group compared with the control group. The cumulative postoperative consumption of fentanyl at 6, 9, and 24 hours was not significantly different between groups. AB - CONCLUSIONS: After RC with lower abdominal ports, superficial wound pain predominates over deep intra-abdominal pain and shoulder pain only at the time of awakening. Afterwards, superficial and deep pain decreased to insignificant levels in 6 hours. Bilateral ultrasound-guided sRSB was effective only during the first hour. This limited benefit should be balanced against the time and risks entailed in performing RSB. RN - 0 (Anesthetics, Local) ES - 1536-5964 IL - 0025-7974 DI - 00005792-201608020-00058 DO - https://dx.doi.org/10.1097/MD.0000000000004445 PT - Journal Article PT - Randomized Controlled Trial ID - 27495072 [pubmed] ID - 10.1097/MD.0000000000004445 [doi] ID - 00005792-201608020-00058 [pii] ID - PMC4979826 [pmc] PP - ppublish LG - English DP - 2016 Aug DC - 20160806 EZ - 2016/08/07 06:00 DA - 2017/02/09 06:00 DT - 2016/08/09 06:00 YR - 2016 ED - 20170208 RD - 20170208 UP - 20170210 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=27495072 <19. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26872808 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Nickel F AU - Hendrie JD AU - Bruckner T AU - Kowalewski KF AU - Kenngott HG AU - Muller-Stich BP AU - Fischer L FA - Nickel, Felix FA - Hendrie, Jonathan D FA - Bruckner, Thomas FA - Kowalewski, Karl F FA - Kenngott, Hannes G FA - Muller-Stich, Beat P FA - Fischer, Lars IN - Nickel, Felix. Department of General, Visceral and Transplantation Surgery, Heidelberg University, INF 110, 69120, Heidelberg, Germany. IN - Hendrie, Jonathan D. Department of General, Visceral and Transplantation Surgery, Heidelberg University, INF 110, 69120, Heidelberg, Germany. IN - Bruckner, Thomas. Institute for Medical Biometry and Informatics, Heidelberg University, INF 305, 69120, Heidelberg, Germany. IN - Kowalewski, Karl F. Department of General, Visceral and Transplantation Surgery, Heidelberg University, INF 110, 69120, Heidelberg, Germany. IN - Kenngott, Hannes G. Department of General, Visceral and Transplantation Surgery, Heidelberg University, INF 110, 69120, Heidelberg, Germany. IN - Muller-Stich, Beat P. Department of General, Visceral and Transplantation Surgery, Heidelberg University, INF 110, 69120, Heidelberg, Germany. IN - Fischer, Lars. Department of General, Visceral and Transplantation Surgery, Heidelberg University, INF 110, 69120, Heidelberg, Germany. lars.fischer@med.uni-heidelberg.de. TI - Successful learning of surgical liver anatomy in a computer-based teaching module. SO - International Journal of Computer Assisted Radiology & Surgery. 11(12):2295-2301, 2016 Dec AS - Int. j. comput. assist. radiol. surg.. 11(12):2295-2301, 2016 Dec NJ - International journal of computer assisted radiology and surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101499225 IO - Int J Comput Assist Radiol Surg SB - Index Medicus CP - Germany MH - *Biliary Tract Surgical Procedures/ed [Education] MH - *Computer-Assisted Instruction MH - Educational Measurement MH - Female MH - Humans MH - *Imaging, Three-Dimensional MH - Liver/ah [Anatomy & Histology] MH - *Liver/su [Surgery] MH - Male MH - Tomography, X-Ray Computed KW - Education; Hepatic; Liver; Oncology; Surgery AB - AIM: To analyze factors influencing the learning of surgical liver anatomy in a computer-based teaching module (TM). AB - METHODS: Medical students in their third to fifth year of training (N [Formula: see text] 410) participated in three randomized trials, each with a different primary hypothesis, comparing two- (2D) and three-dimensional (3D) presentation modes in a TM for surgical liver anatomy. Computed tomography images were presented according to the study and allocation group. Students had to answer eleven questions on surgical liver anatomy and four evaluative questions. Scores and time taken to answer the questions were automatically recorded. Since the three studies used the same 15 questions in the TM, a pooled analysis was performed to compare learning factors across studies. AB - RESULTS: 3D groups had higher scores (7.5 +/- 1.7 vs. 5.6 +/- 2.0; p < 0.001) and needed less time (503.5 +/- 187.4 vs. 603.1 +/- 246.7 s; p < 0.001) than 2D groups. Intensive training improved scores in 2D (p < 0.001). Men gave more correct answers than women, independent of presentation mode (7.2 +/- 2.0 vs. 6.5 +/- 2.1; p [Formula: see text] 0.003). An overall association was found between having fun and higher scores in 11 anatomical questions (p < 0.001). In subgroup analysis, 3D groups had more fun than 2D groups (84.7 vs. 65.1 %; p < 0.001). If given the option, more students in the 2D groups (58.9 %) would have preferred a 3D presentation than students in the 3D group (35.9 %) would have preferred 2D (p < 0.001). AB - CONCLUSION: 3D was superior to 2D for learning of surgical liver anatomy. With training 2D showed similar results. Fun and gender were relevant factors for learning success. ES - 1861-6429 IL - 1861-6410 DI - 10.1007/s11548-016-1354-y DO - https://dx.doi.org/10.1007/s11548-016-1354-y PT - Journal Article PT - Randomized Controlled Trial ID - 26872808 [pubmed] ID - 10.1007/s11548-016-1354-y [doi] ID - 10.1007/s11548-016-1354-y [pii] PP - ppublish PH - 2015/07/03 [received] PH - 2016/01/25 [accepted] LG - English EP - 20160212 DP - 2016 Dec DC - 20160702 EZ - 2016/02/14 06:00 DA - 2017/02/02 06:00 DT - 2016/02/14 06:00 YR - 2016 ED - 20170201 RD - 20170201 UP - 20170203 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26872808 <20. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26806248 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lucereau B AU - Thaveau F AU - Lejay A AU - Roussin M AU - Georg Y AU - Heim F AU - Lee JT AU - Chakfe N FA - Lucereau, Benoit FA - Thaveau, Fabien FA - Lejay, Anne FA - Roussin, Mathieu FA - Georg, Yannick FA - Heim, Frederic FA - Lee, Jason T FA - Chakfe, Nabil IN - Lucereau, Benoit. Department of Vascular Surgery and Kidney Transplantation, University Hospital of Strasbourg, Strasbourg, France. IN - Thaveau, Fabien. Department of Vascular Surgery and Kidney Transplantation, University Hospital of Strasbourg, Strasbourg, France. Electronic address: Fabien.thaveau@chru-strasbourg.fr. IN - Lejay, Anne. Department of Vascular Surgery and Kidney Transplantation, University Hospital of Strasbourg, Strasbourg, France. IN - Roussin, Mathieu. Department of Vascular Surgery and Kidney Transplantation, University Hospital of Strasbourg, Strasbourg, France. IN - Georg, Yannick. Department of Vascular Surgery and Kidney Transplantation, University Hospital of Strasbourg, Strasbourg, France. IN - Heim, Frederic. Laboratoire de Physique et Mecanique des Textiles, Universite de Haute-Alsace, Mulhouse, France. IN - Lee, Jason T. Department of Vascular Surgery, Stanford University Medical Center, Stanford, CA. IN - Chakfe, Nabil. Department of Vascular Surgery and Kidney Transplantation, University Hospital of Strasbourg, Strasbourg, France. TI - Learning Curve of Robotic-Assisted Anastomosis: Shorter than the Laparoscopic Technique? An Educational Study. SO - Annals of Vascular Surgery. 33:39-44, 2016 May AS - Ann Vasc Surg. 33:39-44, 2016 May NJ - Annals of vascular surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - avs, 8703941 IO - Ann Vasc Surg SB - Index Medicus CP - Netherlands MH - Adult MH - Anastomosis, Surgical MH - Blood Vessel Prosthesis MH - *Blood Vessel Prosthesis Implantation/ed [Education] MH - Blood Vessel Prosthesis Implantation/is [Instrumentation] MH - Clinical Competence MH - *Education, Medical, Graduate/mt [Methods] MH - Humans MH - Internship and Residency MH - *Laparoscopy/ed [Education] MH - *Learning Curve MH - Motor Skills MH - Operative Time MH - Polytetrafluoroethylene MH - Prosthesis Design MH - *Robotic Surgical Procedures/ed [Education] MH - Suture Techniques MH - Time Factors AB - BACKGROUND: Achieving aortic anastomosis in laparoscopic surgery remains a technical challenge. The Da Vinci robot could theoretically counteract this issue by minimizing the technical challenge. The aim of this study was to compare the learning curves of performing vascular anastomoses by trainees without any experience using purely laparoscopic versus robotic-assisted techniques. AB - METHODS: Surgery residents were randomly included in the laparoscopic group (group A, n = 3) and the robotic group (group B, n = 3). They performed 10 end-to-end anastomoses on 18-mm-diameter tubular expanded polytetrafluoroethylene grafts. The parameters recorded were duration to complete the anastomosis and an indirect sealing quality evaluation (ISQE) defined as the following ratio: number of stitches with a distance of less than 4 mm/total number of stitches. AB - RESULTS: The mean duration to perform the anastomosis decreased from 2340 s (+/-64) for the first anastomosis to 651 s (+/-248) for the last in group A (P < 0.05) and from 1989 s (+/-556) to 801 s (+/-120) in group B (P < 0.05). The mean ISQE increased from 74% (+/-18) for the first anastomosis to 98% (+/-3) for the last in group A (P < 0.05) and decreased from 100% to 98% (+/-2) in group B (nonsignificant). The mean duration to perform the first anastomosis was lower in group B than in group A (P < 0.05). The mean duration to perform the last anastomosis was not significantly different between the groups. Sealing tended to be better in group B for the first anastomosis compared with group A. AB - CONCLUSIONS: Minimally invasive laparoscopic technique training demonstrates a learning curve to perform vascular anastomoses. The robotic-assisted technique tended to improve suturing skills and should be considered as a valuable tool to reduce the technical learning curve. AB - Copyright © 2016 Elsevier Inc. All rights reserved. RN - 9002-84-0 (Polytetrafluoroethylene) ES - 1615-5947 IL - 0890-5096 DI - S0890-5096(16)30004-8 DO - https://dx.doi.org/10.1016/j.avsg.2015.12.001 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 26806248 [pubmed] ID - S0890-5096(16)30004-8 [pii] ID - 10.1016/j.avsg.2015.12.001 [doi] PP - ppublish PH - 2015/07/03 [received] PH - 2015/12/09 [revised] PH - 2015/12/15 [accepted] LG - English EP - 20160122 DP - 2016 May DC - 20160506 EZ - 2016/01/26 06:00 DA - 2017/02/01 06:00 DT - 2016/01/26 06:00 YR - 2016 ED - 20170131 RD - 20170131 UP - 20170202 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26806248 <21. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27955681 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Park BJ AU - Snider JM AU - Bates NR AU - Cassivi SD AU - Jett GK AU - Sonett JR AU - Toloza EM FA - Park, Bernard J FA - Snider, John M FA - Bates, Nathan R FA - Cassivi, Stephen D FA - Jett, G Kimble FA - Sonett, Joshua R FA - Toloza, Eric M IN - Park, Bernard J. Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 531, New York, NY, 10065, USA. parkb@mskcc.org. IN - Snider, John M. Mercy Health System, Janesville, WI, USA. IN - Bates, Nathan R. Cardiothoracic & Vascular Surgical Associates, Jacksonville, FL, USA. IN - Cassivi, Stephen D. Mayo Clinic, Rochester, MN, USA. IN - Jett, G Kimble. The Heart Hospital Baylor Plano, Plano, TX, USA. IN - Sonett, Joshua R. New York-Presbyterian Hospital, Columbia University, New York, NY, USA. IN - Toloza, Eric M. H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA. TI - Prospective evaluation of biodegradable polymeric sealant for intraoperative air leaks. SO - Journal Of Cardiothoracic Surgery. 11(1):168, 2016 Dec 12 AS - J Cardiothorac Surg. 11(1):168, 2016 Dec 12 NJ - Journal of cardiothoracic surgery PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101265113 IO - J Cardiothorac Surg SB - Index Medicus CP - England MH - Adult MH - Aged MH - Aged, 80 and over MH - Air MH - Anastomotic Leak/et [Etiology] MH - *Anastomotic Leak/th [Therapy] MH - Biocompatible Materials/ad [Administration & Dosage] MH - Female MH - Humans MH - Hydrogels MH - Intraoperative Complications MH - Male MH - Middle Aged MH - *Pneumonectomy/ae [Adverse Effects] MH - Pneumonectomy/mt [Methods] MH - Polyethylene Glycols/ad [Administration & Dosage] MH - Postoperative Complications MH - Prospective Studies MH - Robotic Surgical Procedures MH - Serum Albumin/ad [Administration & Dosage] MH - Thoracic Surgery, Video-Assisted MH - *Tissue Adhesives/ad [Administration & Dosage] MH - Treatment Outcome KW - Intraoperative air leak; Lung cancer; Lung surgery; Pleural air leak sealant; Postoperative air leak; Robotic surgery; Video-assisted thoracic surgery AB - BACKGROUND: A biodegradable polymeric sealant has been previously shown to reduce postoperative air leaks after open pulmonary resection. The aim of this study was to evaluate safety and efficacy during minimally invasive pulmonary resection. AB - METHODS: In a multicenter prospective single-arm trial, 112 patients with a median age of 69 years (range 34-87 years) were treated with sealant for at least one intraoperative air leak after standard methods of repair (sutures, staples or cautery) following minimally invasive pulmonary resection (Video-Assisted Thoracic Surgery (VATS) or Robotic-Assisted). Patients were followed in hospital and 1 month after surgery for procedure-related and device-related complications and presence of air leak. AB - RESULTS: Forty patients had VATS and 72 patients had Robotic-Assisted procedures with the majority (80/112, 71%) undergoing anatomic resection (61 lobectomy, 13 segmentectomy, 6 bilobectomy). There were no device-related adverse events. The overall morbidity rate was 41% (46/112), with major complications occurring in 16.1% (18/112). In-hospital mortality and 30-day mortality were 1.9% (2/103). The majority of intraoperative air leaks (107/133, 81%) were sealed after sealant application, and an additional 16% (21/133) were considered reduced. Forty-nine percent of patients (55/112) were free of air leak throughout the entire postoperative study period. Median chest tube duration was 2 days (range 1 - 46 days), and median length of hospitalization was 3 days (range 1 - 20 days). AB - CONCLUSIONS: This study demonstrated that use of a biodegradable polymer for closure of intraoperative air leaks as an adjunct to standard methods is safe and effective following minimally invasive pulmonary resection. AB - TRIAL REGISTRATION: ClinicalTrials.gov: NCT01867658 . Registered 3 May 2013. RN - 0 (Biocompatible Materials) RN - 0 (Hydrogels) RN - 0 (Serum Albumin) RN - 0 (Tissue Adhesives) RN - 30IQX730WE (Polyethylene Glycols) ES - 1749-8090 IL - 1749-8090 DI - 10.1186/s13019-016-0563-3 DO - https://dx.doi.org/10.1186/s13019-016-0563-3 PT - Clinical Trial PT - Journal Article PT - Multicenter Study ID - 27955681 [pubmed] ID - 10.1186/s13019-016-0563-3 [doi] ID - 10.1186/s13019-016-0563-3 [pii] ID - PMC5154021 [pmc] PP - epublish PH - 2016/06/23 [received] PH - 2016/12/06 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01867658 SL - https://clinicaltrials.gov/search/term=NCT01867658 GI - No: P30 CA008748 Organization: (CA) *NCI NIH HHS* Country: United States LG - English EP - 20161212 DP - 2016 Dec 12 DC - 20161213 EZ - 2016/12/14 06:00 DA - 2017/01/25 06:00 DT - 2016/12/14 06:00 YR - 2016 ED - 20170124 RD - 20170203 UP - 20170206 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=27955681 <22. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27955681 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Park BJ AU - Snider JM AU - Bates NR AU - Cassivi SD AU - Jett GK AU - Sonett JR AU - Toloza EM FA - Park, Bernard J FA - Snider, John M FA - Bates, Nathan R FA - Cassivi, Stephen D FA - Jett, G Kimble FA - Sonett, Joshua R FA - Toloza, Eric M IN - Park, Bernard J. Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 531, New York, NY, 10065, USA. parkb@mskcc.org. IN - Snider, John M. Mercy Health System, Janesville, WI, USA. IN - Bates, Nathan R. Cardiothoracic & Vascular Surgical Associates, Jacksonville, FL, USA. IN - Cassivi, Stephen D. Mayo Clinic, Rochester, MN, USA. IN - Jett, G Kimble. The Heart Hospital Baylor Plano, Plano, TX, USA. IN - Sonett, Joshua R. New York-Presbyterian Hospital, Columbia University, New York, NY, USA. IN - Toloza, Eric M. H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA. TI - Prospective evaluation of biodegradable polymeric sealant for intraoperative air leaks. SO - Journal Of Cardiothoracic Surgery. 11(1):168, 2016 Dec 12 AS - J Cardiothorac Surg. 11(1):168, 2016 Dec 12 NJ - Journal of cardiothoracic surgery PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101265113 IO - J Cardiothorac Surg SB - Index Medicus CP - England MH - Adult MH - Aged MH - Aged, 80 and over MH - Air MH - Anastomotic Leak/et [Etiology] MH - *Anastomotic Leak/th [Therapy] MH - Biocompatible Materials/ad [Administration & Dosage] MH - Female MH - Humans MH - Hydrogels MH - Intraoperative Complications MH - Male MH - Middle Aged MH - *Pneumonectomy/ae [Adverse Effects] MH - Pneumonectomy/mt [Methods] MH - Polyethylene Glycols/ad [Administration & Dosage] MH - Postoperative Complications MH - Prospective Studies MH - Robotic Surgical Procedures MH - Serum Albumin/ad [Administration & Dosage] MH - Thoracic Surgery, Video-Assisted MH - *Tissue Adhesives/ad [Administration & Dosage] MH - Treatment Outcome KW - Intraoperative air leak; Lung cancer; Lung surgery; Pleural air leak sealant; Postoperative air leak; Robotic surgery; Video-assisted thoracic surgery AB - BACKGROUND: A biodegradable polymeric sealant has been previously shown to reduce postoperative air leaks after open pulmonary resection. The aim of this study was to evaluate safety and efficacy during minimally invasive pulmonary resection. AB - METHODS: In a multicenter prospective single-arm trial, 112 patients with a median age of 69 years (range 34-87 years) were treated with sealant for at least one intraoperative air leak after standard methods of repair (sutures, staples or cautery) following minimally invasive pulmonary resection (Video-Assisted Thoracic Surgery (VATS) or Robotic-Assisted). Patients were followed in hospital and 1 month after surgery for procedure-related and device-related complications and presence of air leak. AB - RESULTS: Forty patients had VATS and 72 patients had Robotic-Assisted procedures with the majority (80/112, 71%) undergoing anatomic resection (61 lobectomy, 13 segmentectomy, 6 bilobectomy). There were no device-related adverse events. The overall morbidity rate was 41% (46/112), with major complications occurring in 16.1% (18/112). In-hospital mortality and 30-day mortality were 1.9% (2/103). The majority of intraoperative air leaks (107/133, 81%) were sealed after sealant application, and an additional 16% (21/133) were considered reduced. Forty-nine percent of patients (55/112) were free of air leak throughout the entire postoperative study period. Median chest tube duration was 2 days (range 1 - 46 days), and median length of hospitalization was 3 days (range 1 - 20 days). AB - CONCLUSIONS: This study demonstrated that use of a biodegradable polymer for closure of intraoperative air leaks as an adjunct to standard methods is safe and effective following minimally invasive pulmonary resection. AB - TRIAL REGISTRATION: ClinicalTrials.gov: NCT01867658 . Registered 3 May 2013. RN - 0 (Biocompatible Materials) RN - 0 (Hydrogels) RN - 0 (Serum Albumin) RN - 0 (Tissue Adhesives) RN - 30IQX730WE (Polyethylene Glycols) ES - 1749-8090 IL - 1749-8090 DI - 10.1186/s13019-016-0563-3 DO - https://dx.doi.org/10.1186/s13019-016-0563-3 PT - Clinical Trial PT - Journal Article PT - Multicenter Study ID - 10.1186/s13019-016-0563-3 [doi] ID - 10.1186/s13019-016-0563-3 [pii] ID - PMC5154021 [pmc] PP - epublish PH - 2016/06/23 [received] PH - 2016/12/06 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01867658 SL - https://clinicaltrials.gov/search/term=NCT01867658 GI - No: P30 CA008748 Organization: (CA) *NCI NIH HHS* Country: United States LG - English EP - 20161212 DP - 2016 Dec 12 DC - 20161213 EZ - 2016/12/14 06:00 DA - 2017/01/25 06:00 DT - 2016/12/14 06:00 YR - 2016 ED - 20170124 RD - 20170410 UP - 20170411 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=27955681 <23. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26197796 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Mercante G AU - Masiello A AU - Sperduti I AU - Cristalli G AU - Pellini R AU - Spriano G FA - Mercante, Giuseppe FA - Masiello, Alessandra FA - Sperduti, Isabella FA - Cristalli, Giovanni FA - Pellini, Raul FA - Spriano, Giuseppe IN - Mercante, Giuseppe. Department of Otolaryngology-Head and Neck Surgery (Head: G. Mercante, MD), Regina Elena National Cancer Institute, Rome, Italy. Electronic address: mercante.giuseppe@gmail.com. IN - Masiello, Alessandra. Department of Otolaryngology-Head and Neck Surgery (Head: G. Mercante, MD), Regina Elena National Cancer Institute, Rome, Italy. IN - Sperduti, Isabella. Biostatistics-Scientific Direction, Regina Elena National Cancer Institute, Rome, Italy. IN - Cristalli, Giovanni. Department of Otolaryngology-Head and Neck Surgery (Head: G. Mercante, MD), Regina Elena National Cancer Institute, Rome, Italy. IN - Pellini, Raul. Department of Otolaryngology-Head and Neck Surgery (Head: G. Mercante, MD), Regina Elena National Cancer Institute, Rome, Italy. IN - Spriano, Giuseppe. Department of Otolaryngology-Head and Neck Surgery (Head: G. Mercante, MD), Regina Elena National Cancer Institute, Rome, Italy. TI - Quality of life and functional evaluation in patients with tongue base tumors treated exclusively with transoral robotic surgery: A 1-year follow-up study. SO - Journal of Cranio-Maxillo-Facial Surgery. 43(8):1561-6, 2015 Oct AS - J Craniomaxillofac Surg. 43(8):1561-6, 2015 Oct NJ - Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - htd, 8704309 IO - J Craniomaxillofac Surg SB - Dental Journals SB - Index Medicus CP - Scotland MH - Adult MH - Aged MH - Carcinoma/px [Psychology] MH - Carcinoma/su [Surgery] MH - Cohort Studies MH - Deglutition/ph [Physiology] MH - Deglutition Disorders/et [Etiology] MH - Deglutition Disorders/px [Psychology] MH - Endoscopy/mt [Methods] MH - Female MH - Follow-Up Studies MH - Humans MH - Magnetic Resonance Imaging/mt [Methods] MH - Male MH - Middle Aged MH - Oropharyngeal Neoplasms/px [Psychology] MH - Oropharyngeal Neoplasms/su [Surgery] MH - Positron-Emission Tomography/mt [Methods] MH - Prospective Studies MH - *Quality of Life MH - Recovery of Function/ph [Physiology] MH - Respiratory Aspiration/et [Etiology] MH - Respiratory Aspiration/px [Psychology] MH - *Robotic Surgical Procedures/mt [Methods] MH - Robotic Surgical Procedures/px [Psychology] MH - *Tongue/ph [Physiology] MH - Tongue Neoplasms/px [Psychology] MH - *Tongue Neoplasms/su [Surgery] MH - Voice/ph [Physiology] MH - Voice Disorders/et [Etiology] MH - Voice Disorders/px [Psychology] KW - Base of tongue; Oropharyngeal cancer; Quality of life; Swallowing; TORS; Trans-oral robotic surgery AB - BACKGROUND: To evaluate quality-of-life (QoL), swallowing and voice in patients with base of tongue (BOT) tumors treated with transoral robotic surgery (TORS) alone without any adjuvant treatment. AB - METHODS: The study was a prospective, single-center cohort trial. Swallowing, QoL and voice were evaluated in 13 patients with T1 or T2 oropharyngeal carcinomas of the BOT. Patients underwent evaluation using the following: a dysphagia score (DS); fiberoptic endoscopic evaluation-of-swallowing with the penetration aspiration scale (PAS); the MD Anderson Dysphagia Inventory (MDADI); and the Voice Handicap Index-10 (VHI-10). AB - RESULTS: Subjective (DS) and objective (PAS) evaluation of swallowing produced mean scores of 1.08, 2.23 and 1.46 before surgery and at 6 and 12 months after surgery, respectively, for both tests. A significant difference was found when comparing DS and PAS data at baseline and 6 months after surgery; while no difference was observed between the baseline and 12 months after surgery. The mean values of the MDADI and VHI scores recorded before surgery, and at 6 and 12 months after surgery did not show any statistical difference. AB - CONCLUSIONS: Objective swallowing deterioration in the first 6 months after TORS alone for BOT tumors was possible, but complete recovery of deglutition was observed within 12 months. No changes were reported in the patients' self-perceived status of swallowing and voice dysfunction, and related QoL after 1 year. AB - Copyright © 2015 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved. ES - 1878-4119 IL - 1010-5182 DI - S1010-5182(15)00201-2 DO - https://dx.doi.org/10.1016/j.jcms.2015.06.024 PT - Comparative Study PT - Journal Article PT - Observational Study ID - 26197796 [pubmed] ID - S1010-5182(15)00201-2 [pii] ID - 10.1016/j.jcms.2015.06.024 [doi] PP - ppublish PH - 2015/01/27 [received] PH - 2015/06/15 [revised] PH - 2015/06/19 [accepted] LG - English EP - 20150627 DP - 2015 Oct DC - 20150924 EZ - 2015/07/23 06:00 DA - 2017/01/24 06:00 DT - 2015/07/23 06:00 YR - 2015 ED - 20170123 RD - 20170123 UP - 20170125 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26197796 <24. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26597229 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Varda BK AU - Johnson EK AU - Johnson KL AU - Rosoklija I AU - Baum MA AU - Nelson CP FA - Varda, Briony K FA - Johnson, Emilie K FA - Johnson, Kathryn L FA - Rosoklija, Ilina FA - Baum, Michelle A FA - Nelson, Caleb P IN - Varda, Briony K. Harvard Medical School, Brigham and Women's Hospital, Division of Urology, Boston, MA, USA. Electronic address: bvarda@partners.org. IN - Johnson, Emilie K. Harvard Medical School, Boston Children's Hospital, Department of Urology, Boston, MA, USA. IN - Johnson, Kathryn L. Harvard Medical School, Boston Children's Hospital, Department of Urology, Boston, MA, USA. IN - Rosoklija, Ilina. Harvard Medical School, Boston Children's Hospital, Department of Urology, Boston, MA, USA. IN - Baum, Michelle A. Harvard Medical School, Boston Children's Hospital, Division of Nephrology, Boston, MA, USA. IN - Nelson, Caleb P. Harvard Medical School, Boston Children's Hospital, Department of Urology, Boston, MA, USA. TI - Imaging and surgical utilization for pediatric cystinuria patients: A single-institution cohort study. CM - Comment in: J Pediatr Urol. 2016 Apr;12(2):107; PMID: 26683112 CM - Comment in: J Urol. 2016 May;195(5):1576-7; PMID: 27186779 SO - Journal of pediatric urology. 12(2):106.e1-7, 2016 Apr AS - J Pediatr Urol. 12(2):106.e1-7, 2016 Apr NJ - Journal of pediatric urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101233150 IO - J Pediatr Urol SB - Index Medicus CP - England MH - Adolescent MH - Child MH - *Cystinuria/di [Diagnosis] MH - Cystinuria/su [Surgery] MH - Diagnosis, Differential MH - *Diagnostic Imaging/ut [Utilization] MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Reproducibility of Results MH - Retrospective Studies MH - Treatment Outcome MH - Ureteroscopy/mt [Methods] MH - Urography/mt [Methods] MH - *Urologic Surgical Procedures/ut [Utilization] KW - Cystinuria; Disease burden; Urolithiasis AB - OBJECTIVE: Although cystinuria is rare, its clinical manifestations are life-long. Little is known about healthcare utilization in this population. AB - STUDY DESIGN: Through billing records and chart review, we identified pediatric patients with cystinuria treated at our institution. Variables included demographics, gender, race, comorbidities, location of presentation, presenting symptoms, initial laboratory data, and stone characteristics. Outcomes included the number and type of imaging tests and procedures performed. Descriptive statistics were performed. Median annual frequencies of procedures and imaging were calculated. AB - RESULTS: Twenty-three patients who presented between 1995 and 2011 were identified. The median age at presentation was 12 years, 48% of our patients were male, and 91% were Caucasian. Median follow-up was 4.6 years. Over half were diagnosed in clinic (13/23), while 30% (7/23) presented to the ED. Pain was the most common presenting symptom (13/23), followed by nausea/vomiting (6/23), gross hematuria (5/23), and fevers (5/23). Only one patient presented with acute renal failure. Five patients were discovered by sibling screening. The median number of stones at presentation was two and median size of the largest stone was 9 mm, with three staghorn calculi. During follow-up, a total of 110 stone procedures were performed in 15 patients. Five patients underwent 13 PCNLs, 11 patients underwent 44 ureteroscopy procedures, and nine underwent open or robotic surgery, including one nephrectomy. Among patients identified by sibling screening, most (4/5) were managed with medical therapy alone. A total of 390 imaging procedures were performed. Radiation-associated imaging comprised half of all imaging tests. AB - DISCUSSION: The high rates of imaging and surgical utilization among pediatric cystinuria patients reflect the morbidity of this condition and the need for preventative management. By practicing the ALARA principle during urologic procedures, urologists can reduce radiation exposure. Multiple procedures are often required to render patients stone-free. URS/LL and PCNL are likely to be more effective than ESWL. In complex cases, robotic-assist lithotomy provides the advantage of a minimally invasive approach. Both sibling screening and transitional care represent long-term strategies with the potential to reduce life-long morbidity. The limitations of this study include its small sample size, retrospective nature, and single-center experience. AB - CONCLUSIONS: Our study demonstrates that the clinical impact of disease among pediatric patients presenting with cystinuria at our institution is considerable, with most requiring surgery. Our population also generates heavy utilization of diagnostic imaging. Given the lifelong nature of this disease, research on improved preventive therapies is urgently needed. AB - Copyright © 2015 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved. ES - 1873-4898 IL - 1477-5131 DI - S1477-5131(15)00365-4 DO - https://dx.doi.org/10.1016/j.jpurol.2015.08.019 PT - Journal Article PT - Research Support, N.I.H., Extramural ID - 26597229 [pubmed] ID - S1477-5131(15)00365-4 [pii] ID - 10.1016/j.jpurol.2015.08.019 [doi] PP - ppublish PH - 2014/12/17 [received] PH - 2015/08/31 [accepted] GI - No: K23-DK088943 Organization: (DK) *NIDDK NIH HHS* Country: United States LG - English EP - 20151022 DP - 2016 Apr DC - 20160422 EZ - 2015/11/25 06:00 DA - 2015/11/26 06:00 DT - 2015/11/26 06:00 YR - 2016 ED - 20170117 RD - 20170117 UP - 20170119 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26597229 <25. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26307199 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Zygomalas A AU - Karavias D AU - Koutsouris D AU - Maroulis I AU - Karavias DD AU - Giokas K AU - Megalooikonomou V FA - Zygomalas, Apollon FA - Karavias, Dionissios FA - Koutsouris, Dimitrios FA - Maroulis, Ioannis FA - Karavias, Dimitrios D FA - Giokas, Konstantinos FA - Megalooikonomou, Vasileios IN - Zygomalas, Apollon. Hepatobiliary and Pancreatic Unit, Department of Surgery, University Hospital of Patras, 26500, Patras, Greece. azygomalas@upatras.gr. IN - Zygomalas, Apollon. Computer Engineering and Informatics Department, School of Engineering, University of Patras, 26500, Rio, Patras, Greece. azygomalas@upatras.gr. IN - Karavias, Dionissios. Hepatobiliary and Pancreatic Unit, Department of Surgery, University Hospital of Patras, 26500, Patras, Greece. IN - Koutsouris, Dimitrios. Biomedical Engineering Laboratory, School of Electrical and Computer Engineering, National Technical University of Athens, 15780, Zografou, Athens, Greece. IN - Maroulis, Ioannis. Hepatobiliary and Pancreatic Unit, Department of Surgery, University Hospital of Patras, 26500, Patras, Greece. IN - Karavias, Dimitrios D. Hepatobiliary and Pancreatic Unit, Department of Surgery, University Hospital of Patras, 26500, Patras, Greece. IN - Giokas, Konstantinos. Biomedical Engineering Laboratory, School of Electrical and Computer Engineering, National Technical University of Athens, 15780, Zografou, Athens, Greece. IN - Megalooikonomou, Vasileios. Computer Engineering and Informatics Department, School of Engineering, University of Patras, 26500, Rio, Patras, Greece. TI - Computer-assisted liver tumor surgery using a novel semiautomatic and a hybrid semiautomatic segmentation algorithm. SO - Medical & Biological Engineering & Computing. 54(5):711-21, 2016 May AS - Med Biol Eng Comput. 54(5):711-21, 2016 May NJ - Medical & biological engineering & computing PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - lpn, 7704869 IO - Med Biol Eng Comput SB - Index Medicus CP - United States MH - Adult MH - Aged MH - *Algorithms MH - Female MH - Humans MH - Imaging, Three-Dimensional MH - Liver/pa [Pathology] MH - Liver/su [Surgery] MH - Liver Neoplasms/dg [Diagnostic Imaging] MH - *Liver Neoplasms/su [Surgery] MH - Male MH - Middle Aged MH - Organ Size MH - Reproducibility of Results MH - *Surgery, Computer-Assisted KW - Computer-assisted surgery; Hepatectomy; Liver neoplasms; Liver segmentation; Liver tumor AB - We developed a medical image segmentation and preoperative planning application which implements a semiautomatic and a hybrid semiautomatic liver segmentation algorithm. The aim of this study was to evaluate the feasibility of computer-assisted liver tumor surgery using these algorithms which are based on thresholding by pixel intensity value from initial seed points. A random sample of 12 patients undergoing elective high-risk hepatectomies at our institution was prospectively selected to undergo computer-assisted surgery using our algorithms (June 2013-July 2014). Quantitative and qualitative evaluation was performed. The average computer analysis time (segmentation, resection planning, volumetry, visualization) was 45 min/dataset. The runtime for the semiautomatic algorithm was <0.2 s/slice. Liver volumetric segmentation using the hybrid method was achieved in 12.9 s/dataset (SD +/- 6.14). Mean similarity index was 96.2 % (SD +/- 1.6). The future liver remnant volume calculated by the application showed a correlation of 0.99 to that calculated using manual boundary tracing. The 3D liver models and the virtual liver resections had an acceptable coincidence with the real intraoperative findings. The patient-specific 3D models produced using our semiautomatic and hybrid semiautomatic segmentation algorithms proved to be accurate for the preoperative planning in liver tumor surgery and effectively enhanced the intraoperative medical image guidance. ES - 1741-0444 IL - 0140-0118 DI - 10.1007/s11517-015-1369-5 DO - https://dx.doi.org/10.1007/s11517-015-1369-5 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 26307199 [pubmed] ID - 10.1007/s11517-015-1369-5 [doi] ID - 10.1007/s11517-015-1369-5 [pii] PP - ppublish PH - 2015/02/27 [received] PH - 2015/08/07 [accepted] LG - English EP - 20150826 DP - 2016 May DC - 20160419 EZ - 2015/08/27 06:00 DA - 2017/01/10 06:00 DT - 2015/08/27 06:00 YR - 2016 ED - 20170109 RD - 20170110 UP - 20170111 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26307199 <26. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26337521 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Martinschek A AU - Pfalzgraf D AU - Rafail B AU - Ritter M AU - Heinrich E AU - Trojan L FA - Martinschek, A FA - Pfalzgraf, D FA - Rafail, B FA - Ritter, M FA - Heinrich, E FA - Trojan, L IN - Martinschek, A. Department of Urology, University Medical Centre Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. IN - Martinschek, A. Department of Urology, German Military Hospital Ulm, Oberer Eselsberg 40, 89081, Ulm, Germany. IN - Pfalzgraf, D. Department of Urology, University Medical Centre Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. daniel.pfalzgraf@umm.de. IN - Rafail, B. Department of Urology, University Medical Centre Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. IN - Ritter, M. Department of Urology, University Medical Centre Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. IN - Heinrich, E. Department of Urology, University Medical Centre Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. IN - Heinrich, E. Department of Urology, University Medical Centre Gottingen, Robert-Koch-Str. 40, 37075, Gottingen, Germany. IN - Trojan, L. Department of Urology, University Medical Centre Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. IN - Trojan, L. Department of Urology, University Medical Centre Gottingen, Robert-Koch-Str. 40, 37075, Gottingen, Germany. TI - Transurethral versus suprapubic catheter at robot-assisted radical prostatectomy: a prospective randomized trial with 1-year follow-up. SO - World Journal of Urology. 34(3):407-11, 2016 Mar AS - World J Urol. 34(3):407-11, 2016 Mar NJ - World journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - bry, 8307716 IO - World J Urol SB - Index Medicus CP - Germany MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotics/mt [Methods] MH - Time Factors MH - Transurethral Resection of Prostate/mt [Methods] MH - Treatment Outcome MH - Urinary Bladder/pp [Physiopathology] MH - *Urinary Bladder/su [Surgery] MH - *Urinary Catheterization/is [Instrumentation] MH - Urination/ph [Physiology] KW - Bladder neck contracture; Cystostomy; Pain; Prostatectomy; Robotic prostatectomy; Urinary catheterization AB - OBJECTIVE: To evaluate urethral catheter (UC) versus suprapubic tube (SPT) without stenting the anastomosis at robot-assisted radical prostatectomy (RALP) regarding surgical outcome and catheter-associated discomfort. One year after surgery, continence and patient satisfaction were evaluated. AB - MATERIALS AND METHODS: Sixty-two patients undergoing RALP were prospectively randomized to urinary drainage with UC or with SPT. Functional results were assessed with standardized questionnaires (IPSS, IPSS Bother Score, IIEF and Visual Analogue Scale) preoperatively, after catheter removal and 1 year after surgery. Moreover, bother by the catheter as well as pain due to the catheter was assessed. AB - RESULTS: At personal hygiene, SPT was significantly less bothersome on the day of surgery as well as POD 1-6. Pain caused by the catheter did not differ significantly between the two groups except for POD 5 and 6, when the SPT performed significantly better. Differences regarding voiding parameters after catheter removal did not reach statistical significance. One year after surgery, no significant difference between the two groups was found regarding urinary function and IPSS. Though not statistically significant either, the need for the incision of bladder neck contracture (BNC) in two patients in the UC group is of note, as in the SPT group, no BNC occurred. AB - CONCLUSION: Draining the bladder with SPT only is a feasible option in patients undergoing RALP. Patients with SPT are significantly less bothered by the catheter at personal and genital hygiene compared to UC. The risk of BNC seems to be reduced in the SPT group. ES - 1433-8726 IL - 0724-4983 DI - 10.1007/s00345-015-1678-1 DO - https://dx.doi.org/10.1007/s00345-015-1678-1 PT - Journal Article PT - Randomized Controlled Trial ID - 26337521 [pubmed] ID - 10.1007/s00345-015-1678-1 [doi] ID - 10.1007/s00345-015-1678-1 [pii] PP - ppublish PH - 2015/05/24 [received] PH - 2015/08/25 [accepted] LG - English EP - 20150904 DP - 2016 Mar DC - 20160222 EZ - 2015/09/05 06:00 DA - 2016/12/21 06:00 DT - 2015/09/05 06:00 YR - 2016 ED - 20161220 RD - 20161230 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26337521 <27. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26714950 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Colombo PE AU - Bertrand MM AU - Alline M AU - Boulay E AU - Mourregot A AU - Carrere S AU - Quenet F AU - Jarlier M AU - Rouanet P FA - Colombo, Pierre-Emmanuel FA - Bertrand, Martin M FA - Alline, Mathias FA - Boulay, Eric FA - Mourregot, Anne FA - Carrere, Sebastien FA - Quenet, Francois FA - Jarlier, Marta FA - Rouanet, Philippe IN - Colombo, Pierre-Emmanuel. Surgical Oncology Department, Institut regional du Cancer de Montpellier (ICM), Val d'Aurelle, Montpellier, France. IN - Bertrand, Martin M. Surgical Oncology Department, Institut regional du Cancer de Montpellier (ICM), Val d'Aurelle, Montpellier, France. IN - Alline, Mathias. Surgical Oncology Department, Institut regional du Cancer de Montpellier (ICM), Val d'Aurelle, Montpellier, France. IN - Boulay, Eric. Surgical Oncology Department, Institut regional du Cancer de Montpellier (ICM), Val d'Aurelle, Montpellier, France. IN - Mourregot, Anne. Surgical Oncology Department, Institut regional du Cancer de Montpellier (ICM), Val d'Aurelle, Montpellier, France. IN - Carrere, Sebastien. Surgical Oncology Department, Institut regional du Cancer de Montpellier (ICM), Val d'Aurelle, Montpellier, France. IN - Quenet, Francois. Surgical Oncology Department, Institut regional du Cancer de Montpellier (ICM), Val d'Aurelle, Montpellier, France. IN - Jarlier, Marta. Biometrics Unit, Institut regional du Cancer de Montpellier (ICM), Val d'Aurelle, Montpellier, France. IN - Rouanet, Philippe. Surgical Oncology Department, Institut regional du Cancer de Montpellier (ICM), Val d'Aurelle, Montpellier, France. Philippe.Rouanet@icm.unicancer.fr. TI - Robotic Versus Laparoscopic Total Mesorectal Excision (TME) for Sphincter-Saving Surgery: Is There Any Difference in the Transanal TME Rectal Approach? : A Single-Center Series of 120 Consecutive Patients. SO - Annals of Surgical Oncology. 23(5):1594-600, 2016 May AS - Ann Surg Oncol. 23(5):1594-600, 2016 May NJ - Annals of surgical oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - b9r, 9420840 IO - Ann. Surg. Oncol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - Anal Canal/pa [Pathology] MH - *Anal Canal/su [Surgery] MH - *Digestive System Surgical Procedures/mt [Methods] MH - Female MH - Follow-Up Studies MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - Neoplasm Staging MH - *Organ Sparing Treatments/mt [Methods] MH - *Postoperative Complications MH - Prognosis MH - Prospective Studies MH - Rectal Neoplasms/pa [Pathology] MH - *Rectal Neoplasms/su [Surgery] MH - *Robotics/mt [Methods] MH - Survival Rate AB - BACKGROUND: Robotic total mesorectal excision (R-TME), a novel way for minimally invasive treatment of rectal cancer, was shown in previous studies to be safe and effective. However, comparison with laparoscopic total mesorectal excision (L-TME) has drawn contradictory disputes, especially concerning operative high-risk patients. The aim of this study was to compare R-TME and L-TME on the rectal technical approach. AB - METHODS: Between October 2009 and March 2013, a total of 120 consecutive rectal carcinomas, operated for sphincter-saving procedure, were enrolled. The patient population included the last 60 laparoscopic procedures and the first 60 robotic surgeries (six hybrid approaches, then 54 full robotic surgeries). There were no exclusions. AB - RESULTS: Patients' baseline characteristics were similar in both the R-TME and L-TME groups. Outcomes were equivalent for blood loss (200 vs. 100 mL), postoperative hospital stay (12 vs. 11 days), conversion rate (3.2 vs. 4.8 %), lymph nodes yield (15 vs. 19), no positive distal margin (0 %), positive radial margin (6.4 vs. 9.3 %), diverting ileostomy (73 vs. 58 %) and severe morbidity (28 vs. 20 %). Significant differences were found for median operative time (274 vs. 228 min; p = 0.003) and proctectomy performed via transanal approach (1.7 vs. 16.7 %; p = 0.004). The R-TME operative time curve stabilized to 245 min after the first 25 procedures. AB - CONCLUSIONS: For rectal cancer, R-TME may be as feasible and safe as L-TME in terms of technique. In our practice and for difficult cases, R-TME allows complete rectal dissection by an abdominal approach, while L-TME requires a transanal approach. ES - 1534-4681 IL - 1068-9265 DI - 10.1245/s10434-015-5048-4 DO - https://dx.doi.org/10.1245/s10434-015-5048-4 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 26714950 [pubmed] ID - 10.1245/s10434-015-5048-4 [doi] ID - 10.1245/s10434-015-5048-4 [pii] PP - ppublish PH - 2015/07/09 [received] LG - English EP - 20151229 DP - 2016 May DC - 20160331 EZ - 2015/12/31 06:00 DA - 2016/12/21 06:00 DT - 2015/12/31 06:00 YR - 2016 ED - 20161220 RD - 20161230 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26714950 <28. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26272237 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Khan MS AU - Gan C AU - Ahmed K AU - Ismail AF AU - Watkins J AU - Summers JA AU - Peacock JL AU - Rimington P AU - Dasgupta P FA - Khan, Muhammad Shamim FA - Gan, Christine FA - Ahmed, Kamran FA - Ismail, Ahmad Fahim FA - Watkins, Jane FA - Summers, Jennifer A FA - Peacock, Janet L FA - Rimington, Peter FA - Dasgupta, Prokar IN - Khan, Muhammad Shamim. Department of Urology, Guy's and St. Thomas' NHS Foundation Trust, London, UK; MRC Centre for Transplantation, NIHR Biomedical Research Centre, King's College London, Guy's Hospital, London, UK. Electronic address: shamim.khan@gstt.nhs.uk. IN - Gan, Christine. Department of Urology, Guy's and St. Thomas' NHS Foundation Trust, London, UK. IN - Ahmed, Kamran. Department of Urology, Guy's and St. Thomas' NHS Foundation Trust, London, UK. IN - Ismail, Ahmad Fahim. Department of Urology, Guy's and St. Thomas' NHS Foundation Trust, London, UK. IN - Watkins, Jane. Department of Urology, Guy's and St. Thomas' NHS Foundation Trust, London, UK. IN - Summers, Jennifer A. Division of Health and Social Care Research, King's College London, London, UK. IN - Peacock, Janet L. Division of Health and Social Care Research, King's College London, London, UK. IN - Rimington, Peter. Department of Urology, Eastbourne District General Hospital, Eastbourne, East Sussex, UK. IN - Dasgupta, Prokar. Department of Urology, Guy's and St. Thomas' NHS Foundation Trust, London, UK; MRC Centre for Transplantation, NIHR Biomedical Research Centre, King's College London, Guy's Hospital, London, UK. TI - A Single-centre Early Phase Randomised Controlled Three-arm Trial of Open, Robotic, and Laparoscopic Radical Cystectomy (CORAL). CM - Comment in: Eur Urol. 2016 Apr;69(4):622-3; PMID: 26297605 SO - European Urology. 69(4):613-21, 2016 Apr AS - Eur Urol. 69(4):613-21, 2016 Apr NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Aged MH - Cystectomy/ae [Adverse Effects] MH - *Cystectomy/mt [Methods] MH - Cystectomy/mo [Mortality] MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/mo [Mortality] MH - *Laparoscopy MH - London MH - Male MH - Middle Aged MH - Operative Time MH - Postoperative Complications/et [Etiology] MH - Prospective Studies MH - Recovery of Function MH - Risk Factors MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - Robotic Surgical Procedures/mo [Mortality] MH - *Robotic Surgical Procedures MH - Time Factors MH - Treatment Outcome MH - Urinary Bladder Neoplasms/mo [Mortality] MH - Urinary Bladder Neoplasms/pa [Pathology] MH - *Urinary Bladder Neoplasms/su [Surgery] KW - Complications; Minimally invasive surgery; Muscle-invasive bladder cancer; Radical cystectomy; Robotic surgery AB - BACKGROUND: Laparoscopic radical cystectomy (LRC) and robot-assisted radical cystectomy (RARC) are increasingly popular, but high-level evidence for these techniques remains lacking. AB - OBJECTIVE: To compare the outcomes of patients undergoing open radical cystectomy (ORC), RARC, and LRC. AB - DESIGN, SETTING, AND PARTICIPANTS: From March 2009 to July 2012, 164 patients requiring radical cystectomy for muscle-invasive bladder cancer or high-risk non-muscle-invasive bladder cancer were invited to participate, with an aim of recruiting 47 patients into each arm. Overall, 93 were suitable for trial inclusion; 60 (65%) agreed and 33 (35%) declined. AB - INTERVENTION: ORC, RARC, or LRC with extracorporeal urinary diversion. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Primary end points were 30- and 90-d complication rates. Secondary end points were perioperative clinical, pathologic, and oncologic outcomes, and quality of life (QoL). The Fisher exact test and analysis of variance were used for statistical analyses. AB - RESULTS AND LIMITATIONS: The 30-d complication rates (classified by the Clavien-Dindo system) varied significantly between the three arms (ORC: 70%; RARC: 55%; LRC: 26%; p=0.024). ORC complication rates were significantly higher than LRC (p<0.01). The 90-d complication rates did not differ significantly between the three arms (ORC: 70%; RARC: 55%; LRC 32%; p=0.068). Mean operative time was significantly longer in RARC compared with ORC or LRC. ORC resulted in a slower return to oral solids than RARC or LRC. There were no significant differences in QoL measures. Major limitations are the small sample size and potential surgeon bias. AB - CONCLUSIONS: The 30-d complication rates varied by type of surgery and were significantly higher in the ORC arm than the LRC arm. There was no significant difference in 90-d Clavien-graded complication rates between the three arms. AB - PATIENT SUMMARY: We compared patients having open, robotic, or laparoscopic bladder removal surgery for bladder cancer and found no difference in Clavien-graded complication rates at 90 d. AB - Copyright © 2015 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(15)00697-1 DO - https://dx.doi.org/10.1016/j.eururo.2015.07.038 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 26272237 [pubmed] ID - S0302-2838(15)00697-1 [pii] ID - 10.1016/j.eururo.2015.07.038 [doi] PP - ppublish PH - 2015/01/25 [received] PH - 2015/07/16 [accepted] GI - No: MR/J006742/1 Organization: *Medical Research Council* Country: United Kingdom Organization: *Medical Research Council* Country: United Kingdom LG - English EP - 20150810 DP - 2016 Apr DC - 20160314 EZ - 2015/08/15 06:00 DA - 2016/12/15 06:00 DT - 2015/08/15 06:00 YR - 2016 ED - 20161213 RD - 20161230 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26272237 <29. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26809755 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tolboom RC AU - Draaisma WA AU - Broeders IA AI - Tolboom, Robert C; ORCID: http://orcid.org/0000-0002-3460-1934 FA - Tolboom, Robert C FA - Draaisma, Werner A FA - Broeders, Ivo A M J IN - Tolboom, Robert C. Department of Surgery, Meander Medical Center, P.O. box 1502, 3800 BM, Amersfoort, The Netherlands. rc.tolboom@meandermc.nl. IN - Tolboom, Robert C. Robotics and Minimal Invasive Surgery, University of Twente, Enschede, The Netherlands. rc.tolboom@meandermc.nl. IN - Draaisma, Werner A. Department of Surgery, Meander Medical Center, P.O. box 1502, 3800 BM, Amersfoort, The Netherlands. IN - Broeders, Ivo A M J. Department of Surgery, Meander Medical Center, P.O. box 1502, 3800 BM, Amersfoort, The Netherlands. iamj.broeders@meandermc.nl. IN - Broeders, Ivo A M J. Robotics and Minimal Invasive Surgery, University of Twente, Enschede, The Netherlands. iamj.broeders@meandermc.nl. TI - Evaluation of conventional laparoscopic versus robot-assisted laparoscopic redo hiatal hernia and antireflux surgery: a cohort study. SO - Journal of Robotic Surgery. 10(1):33-9, 2016 Mar AS - J. robot. surg.. 10(1):33-9, 2016 Mar NJ - Journal of robotic surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101300401 IO - J Robot Surg PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766202 SB - Index Medicus CP - England MH - Female MH - Follow-Up Studies MH - Fundoplication MH - *Gastroesophageal Reflux/su [Surgery] MH - *Hernia, Hiatal/su [Surgery] MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/mt [Methods] MH - Laparoscopy/mo [Mortality] MH - Laparoscopy/sn [Statistics & Numerical Data] MH - *Laparoscopy MH - Length of Stay MH - Male MH - Middle Aged MH - Postoperative Complications MH - Reoperation/ae [Adverse Effects] MH - Reoperation/mt [Methods] MH - Reoperation/mo [Mortality] MH - *Reoperation/sn [Statistics & Numerical Data] MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - Robotic Surgical Procedures/mt [Methods] MH - Robotic Surgical Procedures/mo [Mortality] MH - Robotic Surgical Procedures/sn [Statistics & Numerical Data] MH - *Robotic Surgical Procedures MH - Treatment Failure KW - Da Vinci; Fundoplication; Gastroesophageal reflux; Redo surgery; Robotic surgical procedures AB - Surgery for refractory gastroesophageal reflux disease (GERD) and hiatal hernia leads to recurrence or persisting dysphagia in a minority of patients. Redo antireflux surgery in GERD and hiatal hernia is known for higher morbidity and mortality. This study aims to evaluate conventional versus robot-assisted laparoscopic redo antireflux surgery, with the objective to detect possible advantages for the robot-assisted approach. A single institute cohort of 75 patients who underwent either conventional laparoscopic or robot-assisted laparoscopic redo surgery for recurrent GERD or severe dysphagia between 2008 and 2013 were included in the study. Baseline characteristics, symptoms, medical history, procedural data, hospital stay, complications and outcome were prospectively gathered. The main indications for redo surgery were dysphagia, pyrosis or a combination of both in combination with a proven anatomic abnormality. The mean time to redo surgery was 1.9 and 2.0 years after primary surgery for the conventional and robot-assisted groups, respectively. The number of conversions was lower in the robot-assisted group compared to conventional laparoscopy (1/45 vs. 5/30, p = 0.035) despite a higher proportion of patients with previous surgery by laparotomy (9/45 vs. 1/30, p = 0.038). Median hospital stay was reduced by 1 day (3 vs. 4, p = 0.042). There were no differences in mortality, complications or outcome. Robotic support, when available, can be regarded beneficial in redo surgery for GERD and hiatal hernia. Results of this observational study suggest technical feasibility for minimal-invasive robot-assisted redo surgery after open primary antireflux surgery, a reduced number of conversions and shorter hospital stay. ES - 1863-2491 IL - 1863-2483 DI - 10.1007/s11701-016-0558-z DO - https://dx.doi.org/10.1007/s11701-016-0558-z PT - Journal Article ID - 26809755 [pubmed] ID - 10.1007/s11701-016-0558-z [doi] ID - 10.1007/s11701-016-0558-z [pii] ID - PMC4766202 [pmc] PP - ppublish PH - 2015/07/14 [received] PH - 2016/01/08 [accepted] LG - English EP - 20160125 DP - 2016 Mar DC - 20160225 EZ - 2016/01/27 06:00 DA - 2016/12/15 06:00 DT - 2016/01/27 06:00 YR - 2016 ED - 20161213 RD - 20161230 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26809755 <30. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26964911 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Valdis M AU - Chu MW AU - Schlachta C AU - Kiaii B FA - Valdis, Matthew FA - Chu, Michael W A FA - Schlachta, Christopher FA - Kiaii, Bob IN - Valdis, Matthew. Division of Cardiac Surgery, Department of Surgery, Western University, London Health Sciences Centre, London, Ontario, Canada. Electronic address: matthew.valdis@gmail.com. IN - Chu, Michael W A. Division of Cardiac Surgery, Department of Surgery, Western University, London Health Sciences Centre, London, Ontario, Canada. IN - Schlachta, Christopher. Division of General Surgery, Department of Surgery, Western University, London Health Sciences Centre, London, Ontario, Canada. IN - Kiaii, Bob. Division of Cardiac Surgery, Department of Surgery, Western University, London Health Sciences Centre, London, Ontario, Canada. TI - Evaluation of robotic cardiac surgery simulation training: A randomized controlled trial. SO - Journal of Thoracic & Cardiovascular Surgery. 151(6):1498-1505.e2, 2016 Jun AS - J Thorac Cardiovasc Surg. 151(6):1498-1505.e2, 2016 Jun NJ - The Journal of thoracic and cardiovascular surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - k9j, 0376343 IO - J. Thorac. Cardiovasc. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Animals MH - Clinical Competence MH - *Dissection/ed [Education] MH - Female MH - Humans MH - Male MH - *Mammary Arteries/su [Surgery] MH - *Mitral Valve Annuloplasty/ec [Economics] MH - Ontario MH - *Robotic Surgical Procedures/ed [Education] MH - *Simulation Training/mt [Methods] MH - *Suture Techniques/ed [Education] MH - Swine MH - *Thoracic Surgery/ed [Education] MH - Thoracic Surgery/mt [Methods] MH - User-Computer Interface KW - dry lab; randomized controlled trial; robotic cardiac surgery; simulation training; virtual reality; wet lab AB - OBJECTIVE: To compare the currently available simulation training modalities used to teach robotic surgery. AB - METHODS: Forty surgical trainees completed a standardized robotic 10-cm dissection of the internal thoracic artery and placed 3 sutures of a mitral valve annuloplasty in porcine models and were then randomized to a wet lab, a dry lab, a virtual reality lab, or a control group that received no additional training. All groups trained to a level of proficiency determined by 2 expert robotic cardiac surgeons. All assessments were evaluated using the Global Evaluative Assessment of Robotic Skills in a blinded fashion. AB - RESULTS: Wet lab trainees showed the greatest improvement in time-based scoring and the objective scoring tool compared with the experts (mean, 24.9 +/- 1.7 vs 24.9 +/- 2.6; P = .704). The virtual reality lab improved their scores and met the level of proficiency set by our experts for all primary outcomes (mean, 24.9 +/- 1.7 vs 22.8 +/- 3.7; P = .103). Only the control group trainees were not able to meet the expert level of proficiency for both time-based scores and the objective scoring tool (mean, 24.9 +/- 1.7 vs 11.0 +/- 4.5; P < .001). The average duration of training was shortest for the dry lab and longest for the virtual reality simulation (1.6 hours vs 9.3 hours; P < .001). AB - CONCLUSIONS: We have completed the first randomized controlled trial to objectively compare the different training modalities of robotic surgery. Our data demonstrate the significant benefits of wet lab and virtual reality robotic simulation training and highlight key differences in current training methods. This study can help guide training programs in investing resources in cost-effective, high-yield simulation exercises. AB - Copyright © 2016 The American Association for Thoracic Surgery. All rights reserved. ES - 1097-685X IL - 0022-5223 DI - S0022-5223(16)00234-8 DO - https://dx.doi.org/10.1016/j.jtcvs.2016.02.016 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 26964911 [pubmed] ID - S0022-5223(16)00234-8 [pii] ID - 10.1016/j.jtcvs.2016.02.016 [doi] PP - ppublish PH - 2015/07/15 [received] PH - 2015/10/17 [revised] PH - 2016/02/07 [accepted] LG - English EP - 20160213 DP - 2016 Jun DC - 20160521 EZ - 2016/03/12 06:00 DA - 2016/12/15 06:00 DT - 2016/03/12 06:00 YR - 2016 ED - 20161213 RD - 20161230 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26964911 <31. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26908528 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Rasmussen KC AU - Hojskov M AU - Ruhnau B AU - Salling L AU - Pedersen T AU - Goetze JP AU - Secher NH FA - Rasmussen, Kirsten C FA - Hojskov, Michael FA - Ruhnau, Birgitte FA - Salling, Lisbeth FA - Pedersen, Tom FA - Goetze, Jens P FA - Secher, Niels H IN - Rasmussen, Kirsten C. Departments of Anaesthesiology, Rigshospitalet, Copenhagen, Denmark. IN - Hojskov, Michael. Departments of Anaesthesiology, Rigshospitalet, Copenhagen, Denmark. IN - Ruhnau, Birgitte. Departments of Anaesthesiology, Rigshospitalet, Copenhagen, Denmark. IN - Salling, Lisbeth. Department of Urology, Rigshospitalet, Copenhagen, Denmark. IN - Pedersen, Tom. Center for Head and Orthopaedic Surgery, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. IN - Goetze, Jens P. Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark. IN - Secher, Niels H. Departments of Anaesthesiology, Rigshospitalet, Copenhagen, Denmark. TI - Plasma pro-atrial natriuretic peptide to indicate fluid balance during cystectomy: a prospective observational study. SO - BMJ Open. 6(2):e010323, 2016 Feb 23 AS - BMJ Open. 6(2):e010323, 2016 Feb 23 NJ - BMJ open PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101552874 IO - BMJ Open PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769390 SB - Index Medicus CP - England MH - Aged MH - *Atrial Natriuretic Factor/bl [Blood] MH - Blood Loss, Surgical/sn [Statistics & Numerical Data] MH - *Cystectomy MH - Female MH - Humans MH - Isotonic Solutions/ad [Administration & Dosage] MH - Length of Stay MH - Male MH - Middle Aged MH - Postoperative Complications/bl [Blood] MH - Prospective Studies MH - Treatment Outcome MH - *Water-Electrolyte Balance AB - OBJECTIVES: During surgery the volume of administered fluid is debated. Pro-atrial natriuretic peptide (proANP) is released by atrial distension, and we evaluated the relationship between changes in proANP associated with perioperative fluid balance. AB - DESIGN: Prospective observational study. AB - SETTING: One university/tertiary centre. AB - PARTICIPANTS: The study included patients who underwent radical cystectomy. Plasma for determination of proANP was obtained before surgery, after resection of the bladder, and at the end of surgery for 20 robotic-assisted radical cystectomy (RARC) and 20 open radical cystectomy (ORC) procedures. AB - RESULTS: The blood loss was 1871 (95% CI 1267 to 2475) vs 589 mL (378 to 801) in the ORC and RARC groups (p=0.001), respectively, and fluid balance was positive by 1518 mL (1215 to 1821) during ORC, and by 1858 mL (1461 to 2255) during RARC (p=0.163). Yet, at the end of ORC, plasma proANP was reduced by 23% (14% to 32%, p=0.001), while plasma proANP did not change significantly during RARC. Thus, plasma proANP was associated both with the perioperative blood loss (r= -0.475 (0.632 to -0.101), p=0.002), and with fluid balance (r=0.561 (0.302 to 0.740), p=0.001), indicating that a stable plasma proANP required a fluid surplus by 2.4 L (2.0 to 2.7). AB - CONCLUSIONS: There was a correlation between intraoperative haemorrhage and a decrease in plasma proANP and, taking plasma proANP to indicate filling of the heart, about 2.5 L surplus volume of lactated Ringer's solution appears to maintain cardiac preload during cystectomy. AB - TRIAL REGISTRATION NUMBER: EudraCT (2012-005040-20), Results. AB - Copyright Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ RN - 0 (Isotonic Solutions) RN - 8026-10-6 (Ringer's solution) RN - 85637-73-6 (Atrial Natriuretic Factor) ES - 2044-6055 IL - 2044-6055 DI - bmjopen-2015-010323 DO - https://dx.doi.org/10.1136/bmjopen-2015-010323 PT - Journal Article PT - Observational Study PT - Research Support, Non-U.S. Gov't ID - 26908528 [pubmed] ID - bmjopen-2015-010323 [pii] ID - 10.1136/bmjopen-2015-010323 [doi] ID - PMC4769390 [pmc] PP - epublish SI - Dryad SI - EudraCT SA - Dryad/56NP2 SA - EudraCT/2012-005040-20 LG - English EP - 20160223 DP - 2016 Feb 23 DC - 20160224 EZ - 2016/02/25 06:00 DA - 2016/12/15 06:00 DT - 2016/02/26 06:00 YR - 2016 ED - 20161213 RD - 20161230 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26908528 <32. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26645072 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Fujiwara K AU - Fukuhara T AU - Kitano H AU - Fujii T AU - Koyama S AU - Yamasaki A AU - Kataoka H AU - Takeuchi H FA - Fujiwara, Kazunori FA - Fukuhara, Takahiro FA - Kitano, Hiroya FA - Fujii, Taihei FA - Koyama, Satoshi FA - Yamasaki, Aigo FA - Kataoka, Hideyuki FA - Takeuchi, Hiromi IN - Fujiwara, Kazunori. Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, Tottori University, 36-1, Nishimachi, Yonago, 683-8504, Japan. kfujiwa@med.tottori-u.ac.jp. IN - Fukuhara, Takahiro. Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, Tottori University, 36-1, Nishimachi, Yonago, 683-8504, Japan. IN - Kitano, Hiroya. Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, Tottori University, 36-1, Nishimachi, Yonago, 683-8504, Japan. IN - Fujii, Taihei. Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, Tottori University, 36-1, Nishimachi, Yonago, 683-8504, Japan. IN - Koyama, Satoshi. Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, Tottori University, 36-1, Nishimachi, Yonago, 683-8504, Japan. IN - Yamasaki, Aigo. Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, Tottori University, 36-1, Nishimachi, Yonago, 683-8504, Japan. IN - Kataoka, Hideyuki. Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, Tottori University, 36-1, Nishimachi, Yonago, 683-8504, Japan. IN - Takeuchi, Hiromi. Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, Tottori University, 36-1, Nishimachi, Yonago, 683-8504, Japan. TI - Preliminary study of transoral robotic surgery for pharyngeal cancer in Japan. SO - Journal of Robotic Surgery. 10(1):11-7, 2016 Mar AS - J. robot. surg.. 10(1):11-7, 2016 Mar NJ - Journal of robotic surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101300401 IO - J Robot Surg PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766218 SB - Index Medicus CP - England MH - Aged MH - Aged, 80 and over MH - Female MH - Humans MH - Japan MH - Male MH - Middle Aged MH - *Pharyngeal Neoplasms/su [Surgery] MH - Postoperative Complications MH - Prospective Studies MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures/mt [Methods] MH - Robotic Surgical Procedures/sn [Statistics & Numerical Data] KW - Head and neck cancer; Pharyngeal cancer; Single-institute clinical trail; Transoral robotic surgery (TORS) AB - Transoral robotic surgery (TORS) with the da Vinci Surgical System has been used for the removal of pharyngeal and laryngeal cancers with the objective to improve functional and aesthetic outcomes without worsening survival. While TORS has been approved in many countries, Japan's FDA has not yet done so. Our hospital started using TORS with the approval of the Ethical Review Board and the Minimum Invasive Surgical Center Committee at Tottori University. No surgical outcomes of TORS for Japanese patients with head and neck cancer have been reported in Japan. This paper deals with the outcomes and feasibility of TORS for Japanese patients with pharyngeal cancer at our institution. TORS was performed for 10 patients with T1, T2, T3 oropharyngeal and hypopharyngeal squamous cell carcinoma between 2013 and 2014. This is a single-institutional study. TORS could be completed for all cases, except one patient that was not candidate, and no intraoperative conversion to an open surgical procedure was required. Five patients underwent neck dissection, two of them concurrent and three staged. Of all patients, positive surgical margins were detected in two. The average blood loss including neck dissection was 21.5 +/- 33.4 ml, the operation time was 183 +/- 36 min and the console time was 103 +/- 22 min. No tracheostomy had been performed either pre- or postoperatively, and there was no difference between preoperative and postoperative swallowing functions. In this single-institutional preliminary study, we demonstrated that TORS is a feasible and safe treatment. A clinical multi-institutional study of TORS for laryngopharyngeal cancer has been approved as an advanced medical system study and is under way. In the near future, it is expected that the efficacy and safety of TORS for laryngopharyngeal cancer will be confirmed as the result of this multiple-institutional clinical study in Japan. ES - 1863-2491 IL - 1863-2483 DI - 10.1007/s11701-015-0547-7 DO - https://dx.doi.org/10.1007/s11701-015-0547-7 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 26645072 [pubmed] ID - 10.1007/s11701-015-0547-7 [doi] ID - 10.1007/s11701-015-0547-7 [pii] ID - PMC4766218 [pmc] PP - ppublish PH - 2015/10/11 [received] PH - 2015/11/22 [accepted] LG - English EP - 20151208 DP - 2016 Mar DC - 20160225 EZ - 2015/12/10 06:00 DA - 2016/12/15 06:00 DT - 2015/12/10 06:00 YR - 2016 ED - 20161213 RD - 20161230 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26645072 <33. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25982464 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Morelli L AU - Guadagni S AU - Di Franco G AU - Palmeri M AU - Caprili G AU - D'isidoro C AU - Pisano R AU - Marciano E AU - Moglia A AU - Di Candio G AU - Mosca F AI - Palmeri, Matteo; ORCID: http://orcid.org/0000-0002-9343-278X FA - Morelli, Luca FA - Guadagni, Simone FA - Di Franco, Gregorio FA - Palmeri, Matteo FA - Caprili, Giovanni FA - D'isidoro, Cristiano FA - Pisano, Roberta FA - Marciano, Emanuele FA - Moglia, Andrea FA - Di Candio, Giulio FA - Mosca, Franco IN - Morelli, Luca. General Surgery Unit, Department of Oncology, Transplantation and New Technologies, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy. IN - Morelli, Luca. EndoCAS (Center for Computer Assisted Surgery), University of Pisa, Pisa, Italy. IN - Guadagni, Simone. General Surgery Unit, Department of Oncology, Transplantation and New Technologies, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy. IN - Di Franco, Gregorio. General Surgery Unit, Department of Oncology, Transplantation and New Technologies, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy. IN - Palmeri, Matteo. General Surgery Unit, Department of Oncology, Transplantation and New Technologies, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy. palmeri.matteo@gmail.com. IN - Caprili, Giovanni. General Surgery Unit, Department of Oncology, Transplantation and New Technologies, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy. IN - D'isidoro, Cristiano. General Surgery Unit, Department of Oncology, Transplantation and New Technologies, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy. IN - Pisano, Roberta. General Surgery Unit, Department of Oncology, Transplantation and New Technologies, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy. IN - Marciano, Emanuele. General Surgery Unit, Department of Oncology, Transplantation and New Technologies, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy. IN - Moglia, Andrea. EndoCAS (Center for Computer Assisted Surgery), University of Pisa, Pisa, Italy. IN - Di Candio, Giulio. General Surgery Unit, Department of Oncology, Transplantation and New Technologies, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy. IN - Mosca, Franco. EndoCAS (Center for Computer Assisted Surgery), University of Pisa, Pisa, Italy. TI - Short-term clinical outcomes of robot-assisted intersphincteric resection and low rectal resection with double-stapling technique for cancer: a case-matched study. SO - International Journal of Colorectal Disease. 31(3):737-9, 2016 Mar AS - Int J Colorectal Dis. 31(3):737-9, 2016 Mar NJ - International journal of colorectal disease PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - itf, 8607899 IO - Int J Colorectal Dis SB - Index Medicus CP - Germany MH - Aged MH - *Anal Canal/su [Surgery] MH - Case-Control Studies MH - *Digestive System Surgical Procedures/mt [Methods] MH - Female MH - Humans MH - Male MH - *Rectal Neoplasms/su [Surgery] MH - *Robotics/mt [Methods] MH - *Surgical Stapling MH - Treatment Outcome ES - 1432-1262 IL - 0179-1958 DI - 10.1007/s00384-015-2237-3 DO - https://dx.doi.org/10.1007/s00384-015-2237-3 PT - Clinical Trial PT - Letter PT - Research Support, Non-U.S. Gov't ID - 25982464 [pubmed] ID - 10.1007/s00384-015-2237-3 [doi] ID - 10.1007/s00384-015-2237-3 [pii] PP - ppublish PH - 2015/05/08 [accepted] LG - English EP - 20150516 DP - 2016 Mar DC - 20160302 EZ - 2015/05/19 06:00 DA - 2016/12/15 06:00 DT - 2015/05/20 06:00 YR - 2016 ED - 20161213 RD - 20161230 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25982464 <34. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25894448 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tam MS AU - Kaoutzanis C AU - Mullard AJ AU - Regenbogen SE AU - Franz MG AU - Hendren S AU - Krapohl G AU - Vandewarker JF AU - Lampman RM AU - Cleary RK FA - Tam, Michael S FA - Kaoutzanis, Christodoulos FA - Mullard, Andrew J FA - Regenbogen, Scott E FA - Franz, Michael G FA - Hendren, Samantha FA - Krapohl, Greta FA - Vandewarker, James F FA - Lampman, Richard M FA - Cleary, Robert K IN - Tam, Michael S. Division of Colorectal Surgery, Department of Surgery, Saint Joseph Mercy Health System, 5333 McAuley Drive, Suite 2111, Ann Arbor, MI, 48106, USA. IN - Kaoutzanis, Christodoulos. Division of Colorectal Surgery, Department of Surgery, Saint Joseph Mercy Health System, 5333 McAuley Drive, Suite 2111, Ann Arbor, MI, 48106, USA. IN - Mullard, Andrew J. Michigan Surgical Quality Collaborative, University of Michigan Health System, Ann Arbor, MI, USA. IN - Regenbogen, Scott E. Division of Colorectal Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, MI, USA. IN - Franz, Michael G. Division of Colorectal Surgery, Department of Surgery, Saint Joseph Mercy Health System, 5333 McAuley Drive, Suite 2111, Ann Arbor, MI, 48106, USA. IN - Hendren, Samantha. Division of Colorectal Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, MI, USA. IN - Krapohl, Greta. Michigan Surgical Quality Collaborative, University of Michigan Health System, Ann Arbor, MI, USA. IN - Vandewarker, James F. Division of Colorectal Surgery, Department of Surgery, Saint Joseph Mercy Health System, 5333 McAuley Drive, Suite 2111, Ann Arbor, MI, 48106, USA. IN - Lampman, Richard M. Division of Colorectal Surgery, Department of Surgery, Saint Joseph Mercy Health System, 5333 McAuley Drive, Suite 2111, Ann Arbor, MI, 48106, USA. IN - Cleary, Robert K. Division of Colorectal Surgery, Department of Surgery, Saint Joseph Mercy Health System, 5333 McAuley Drive, Suite 2111, Ann Arbor, MI, 48106, USA. Robert.Cleary@stjoeshealth.org. TI - A population-based study comparing laparoscopic and robotic outcomes in colorectal surgery. SO - Surgical Endoscopy. 30(2):455-63, 2016 Feb AS - Surg Endosc. 30(2):455-63, 2016 Feb NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Aged MH - Colonic Diseases/mo [Mortality] MH - *Colonic Diseases/su [Surgery] MH - Colorectal Surgery/mt [Methods] MH - Colorectal Surgery/mo [Mortality] MH - *Colorectal Surgery MH - Female MH - Humans MH - Laparoscopy/mt [Methods] MH - Laparoscopy/mo [Mortality] MH - *Laparoscopy MH - Length of Stay/sn [Statistics & Numerical Data] MH - Male MH - Middle Aged MH - Operative Time MH - Postoperative Complications/mo [Mortality] MH - *Postoperative Complications/su [Surgery] MH - Propensity Score MH - Rectal Diseases/mo [Mortality] MH - *Rectal Diseases/su [Surgery] MH - Rectum/su [Surgery] MH - Retrospective Studies MH - Robotic Surgical Procedures/mt [Methods] MH - Robotic Surgical Procedures/mo [Mortality] MH - *Robotic Surgical Procedures MH - Treatment Outcome MH - United States/ep [Epidemiology] KW - Complication rates; Conversion rates; Hand-assisted laparoscopic colorectal surgery; Laparoscopic colorectal surgery; Length of hospital stay; Robotic colorectal surgery AB - BACKGROUND: Current data addressing the role of robotic surgery for the management of colorectal disease are primarily from single-institution and case-matched comparative studies as well as administrative database analyses. The purpose of this study was to compare minimally invasive surgery outcomes using a large regional protocol-driven database devoted to surgical quality, improvement in patient outcomes, and cost-effectiveness. AB - METHODS: This is a retrospective cohort study from the prospectively collected Michigan Surgical Quality Collaborative registry designed to compare outcomes of patients who underwent elective laparoscopic, hand-assisted laparoscopic, and robotic colon and rectal operations between July 1, 2012 and October 7, 2014. We adjusted for differences in baseline covariates between cases with different surgical approaches using propensity score quintiles modeled on patient demographics, general health factors, diagnosis, and preoperative co-morbidities. The primary outcomes were conversion rates and hospital length of stay. Secondary outcomes included operative time, and postoperative morbidity and mortality. AB - RESULTS: A total of 2735 minimally invasive colorectal operations met inclusion criteria. Conversion rates were lower with robotic as compared to laparoscopic operations, and this was statistically significant for rectal resections (colon 9.0 vs. 16.9%, p < 0.06; rectum 7.8 vs. 21.2%, p < 0.001). The adjusted length of stay for robotic colon operations (4.00 days, 95% CI 3.63-4.40) was significantly shorter compared to laparoscopic (4.41 days, 95% CI 4.17-4.66; p = 0.04) and hand-assisted laparoscopic cases (4.44 days, 95% CI 4.13-4.78; p = 0.008). There were no significant differences in overall postoperative complications among groups. AB - CONCLUSIONS: When compared to conventional laparoscopy, the robotic platform is associated with significantly fewer conversions to open for rectal operations, and significantly shorter length of hospital stay for colon operations, without increasing overall postoperative morbidity. These findings and the recent upgrades in minimally invasive technology warrant continued evaluation of the role of the robotic platform in colorectal surgery. ES - 1432-2218 IL - 0930-2794 DI - 10.1007/s00464-015-4218-6 DO - https://dx.doi.org/10.1007/s00464-015-4218-6 PT - Comparative Study PT - Journal Article PT - Observational Study ID - 25894448 [pubmed] ID - 10.1007/s00464-015-4218-6 [doi] ID - 10.1007/s00464-015-4218-6 [pii] PP - ppublish PH - 2015/01/11 [received] PH - 2015/04/04 [accepted] LG - English EP - 20150417 DP - 2016 Feb DC - 20160202 EZ - 2015/04/21 06:00 DA - 2016/12/15 06:00 DT - 2015/04/22 06:00 YR - 2016 ED - 20161213 RD - 20161230 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25894448 <35. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26964911 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Valdis M AU - Chu MW AU - Schlachta C AU - Kiaii B FA - Valdis, Matthew FA - Chu, Michael W A FA - Schlachta, Christopher FA - Kiaii, Bob IN - Valdis, Matthew. Division of Cardiac Surgery, Department of Surgery, Western University, London Health Sciences Centre, London, Ontario, Canada. Electronic address: matthew.valdis@gmail.com. IN - Chu, Michael W A. Division of Cardiac Surgery, Department of Surgery, Western University, London Health Sciences Centre, London, Ontario, Canada. IN - Schlachta, Christopher. Division of General Surgery, Department of Surgery, Western University, London Health Sciences Centre, London, Ontario, Canada. IN - Kiaii, Bob. Division of Cardiac Surgery, Department of Surgery, Western University, London Health Sciences Centre, London, Ontario, Canada. TI - Evaluation of robotic cardiac surgery simulation training: A randomized controlled trial. CM - Comment in: J Thorac Cardiovasc Surg. 2016 Jun;151(6):1506-7; PMID: 26988267 SO - Journal of Thoracic & Cardiovascular Surgery. 151(6):1498-1505.e2, 2016 Jun AS - J Thorac Cardiovasc Surg. 151(6):1498-1505.e2, 2016 Jun NJ - The Journal of thoracic and cardiovascular surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - k9j, 0376343 IO - J. Thorac. Cardiovasc. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Animals MH - Clinical Competence MH - *Dissection/ed [Education] MH - Female MH - Humans MH - Male MH - *Mammary Arteries/su [Surgery] MH - *Mitral Valve Annuloplasty/ec [Economics] MH - Ontario MH - *Robotic Surgical Procedures/ed [Education] MH - *Simulation Training/mt [Methods] MH - *Suture Techniques/ed [Education] MH - Swine MH - *Thoracic Surgery/ed [Education] MH - Thoracic Surgery/mt [Methods] MH - User-Computer Interface KW - dry lab; randomized controlled trial; robotic cardiac surgery; simulation training; virtual reality; wet lab AB - OBJECTIVE: To compare the currently available simulation training modalities used to teach robotic surgery. AB - METHODS: Forty surgical trainees completed a standardized robotic 10-cm dissection of the internal thoracic artery and placed 3 sutures of a mitral valve annuloplasty in porcine models and were then randomized to a wet lab, a dry lab, a virtual reality lab, or a control group that received no additional training. All groups trained to a level of proficiency determined by 2 expert robotic cardiac surgeons. All assessments were evaluated using the Global Evaluative Assessment of Robotic Skills in a blinded fashion. AB - RESULTS: Wet lab trainees showed the greatest improvement in time-based scoring and the objective scoring tool compared with the experts (mean, 24.9 +/- 1.7 vs 24.9 +/- 2.6; P = .704). The virtual reality lab improved their scores and met the level of proficiency set by our experts for all primary outcomes (mean, 24.9 +/- 1.7 vs 22.8 +/- 3.7; P = .103). Only the control group trainees were not able to meet the expert level of proficiency for both time-based scores and the objective scoring tool (mean, 24.9 +/- 1.7 vs 11.0 +/- 4.5; P < .001). The average duration of training was shortest for the dry lab and longest for the virtual reality simulation (1.6 hours vs 9.3 hours; P < .001). AB - CONCLUSIONS: We have completed the first randomized controlled trial to objectively compare the different training modalities of robotic surgery. Our data demonstrate the significant benefits of wet lab and virtual reality robotic simulation training and highlight key differences in current training methods. This study can help guide training programs in investing resources in cost-effective, high-yield simulation exercises. AB - Copyright © 2016 The American Association for Thoracic Surgery. All rights reserved. ES - 1097-685X IL - 0022-5223 DI - S0022-5223(16)00234-8 DO - https://dx.doi.org/10.1016/j.jtcvs.2016.02.016 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - S0022-5223(16)00234-8 [pii] ID - 10.1016/j.jtcvs.2016.02.016 [doi] PP - ppublish PH - 2015/07/15 [received] PH - 2015/10/17 [revised] PH - 2016/02/07 [accepted] LG - English EP - 20160213 DP - 2016 Jun DC - 20160521 EZ - 2016/03/12 06:00 DA - 2016/12/15 06:00 DT - 2016/03/12 06:00 YR - 2016 ED - 20161213 RD - 20170406 UP - 20170410 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=26964911 <36. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26585582 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lovegrove C AU - Novara G AU - Mottrie A AU - Guru KA AU - Brown M AU - Challacombe B AU - Popert R AU - Raza J AU - Van der Poel H AU - Peabody J AU - Dasgupta P AU - Ahmed K FA - Lovegrove, Catherine FA - Novara, Giacomo FA - Mottrie, Alex FA - Guru, Khurshid A FA - Brown, Matthew FA - Challacombe, Ben FA - Popert, Richard FA - Raza, Johar FA - Van der Poel, Henk FA - Peabody, James FA - Dasgupta, Prokar FA - Ahmed, Kamran IN - Lovegrove, Catherine. King's College London, Guy's Hospital, London, UK. IN - Novara, Giacomo. University of Padua, Padua, Italy. IN - Mottrie, Alex. OLV Clinic, Aalst, Belgium. IN - Guru, Khurshid A. Roswell Park Cancer Institute, Buffalo, NY, USA. IN - Brown, Matthew. Fiona Stanley Hospital, Perth, Australia. IN - Challacombe, Ben. King's College London, Guy's Hospital, London, UK. IN - Popert, Richard. King's College London, Guy's Hospital, London, UK. IN - Raza, Johar. Roswell Park Cancer Institute, Buffalo, NY, USA. IN - Van der Poel, Henk. Netherlands Cancer Institute, Amsterdam, The Netherlands. IN - Peabody, James. Henry Ford Hospital, Detroit, MI, USA. IN - Dasgupta, Prokar. King's College London, Guy's Hospital, London, UK. Electronic address: prokarurol@gmail.com. IN - Ahmed, Kamran. King's College London, Guy's Hospital, London, UK. TI - Structured and Modular Training Pathway for Robot-assisted Radical Prostatectomy (RARP): Validation of the RARP Assessment Score and Learning Curve Assessment. SO - European Urology. 69(3):526-35, 2016 Mar AS - Eur Urol. 69(3):526-35, 2016 Mar NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Australia MH - Clinical Competence MH - Curriculum MH - *Education, Medical, Graduate/mt [Methods] MH - *Educational Measurement/mt [Methods] MH - Educational Status MH - Europe MH - Humans MH - *Learning Curve MH - Linear Models MH - Longitudinal Studies MH - Male MH - Mentors MH - Multivariate Analysis MH - Prospective Studies MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/ed [Education] MH - Reproducibility of Results MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures/ed [Education] MH - *Task Performance and Analysis MH - *Teaching/mt [Methods] MH - United States KW - Assessment; Learning curve; Patient safety; Robot-assisted radical prostatectomy; Training AB - BACKGROUND: Use of robot-assisted radical prostatectomy (RARP) for prostate cancer is increasing. Structured surgical training and objective assessment are critical for outcomes. AB - OBJECTIVE: To develop and validate a modular training and assessment pathway via Healthcare Failure Mode and Effect Analysis (HFMEA) for trainees undertaking RARP and evaluate learning curves (LCs) for procedural steps. AB - DESIGN, SETTING, AND PARTICIPANTS: This multi-institutional (Europe, Australia, and United States) observational prospective study used HFMEA to identify the high-risk steps of RARP. A specialist focus group enabled validation. Fifteen trainees who underwent European Association of Urology robotic surgery curriculum training performed RARP and were assessed by mentors using the tool developed. Results produced LCs for each step. A plateau above score 4 indicated competence. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: We used a modular training and assessment tool (RARP Assessment Score) to evaluate technical skills. LCs were constructed. Multivariable Kruskal-Wallis, Mann-Whitney U, and kappa coefficient analyses were used. AB - RESULTS AND LIMITATIONS: Five surgeons were observed for 42 console hours to map steps of RARP. HFMEA identified 84 failure modes and 46 potential causes with a hazard score >8. Content validation created the RARP Assessment Score: 17 stages and 41 steps. The RARP Assessment Score was acceptable (56.67%), feasible (96.67%), and had educational impact (100%). Fifteen robotic surgery trainees were assessed for 8 mo. In 426 RARP cases (range: 4-79), all procedural steps were attempted by trainees. Trainees were assessed with the RARP Assessment Score by their expert mentors, and LCs for individual steps were plotted. LCs demonstrated plateaus for anterior bladder neck transection (16 cases), posterior bladder neck transection (18 cases), posterior dissection (9 cases), dissection of prostatic pedicle and seminal vesicles (15 cases), and anastomosis (17 cases). Other steps did not plateau during data collection. AB - CONCLUSIONS: The RARP Assessment Score based on HFMEA methodology identified critical steps for focused RARP training and assessed surgeons. LCs demonstrate the experience necessary to reach a level of competence in technical skills to protect patients. AB - PATIENT SUMMARY: We developed a safety and assessment tool to gauge the technical skills of surgeons performing robot-assisted radical prostatectomy. Improvement was monitored, and measures of progress can be used in future to guide mentors when training surgeons to operate safely. AB - Copyright © 2015 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(15)01082-9 DO - https://dx.doi.org/10.1016/j.eururo.2015.10.048 PT - Journal Article PT - Multicenter Study PT - Observational Study PT - Research Support, Non-U.S. Gov't PT - Validation Studies ID - 26585582 [pubmed] ID - S0302-2838(15)01082-9 [pii] ID - 10.1016/j.eururo.2015.10.048 [doi] PP - ppublish PH - 2015/09/28 [received] PH - 2015/10/23 [accepted] GI - No: MR/J006742/1 Organization: *Medical Research Council* Country: United Kingdom Organization: *Department of Health* Country: United Kingdom Organization: *Medical Research Council* Country: United Kingdom LG - English EP - 20151114 DP - 2016 Mar DC - 20160212 EZ - 2015/11/21 06:00 DA - 2016/11/15 06:00 DT - 2015/11/21 06:00 YR - 2016 ED - 20161114 RD - 20161122 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26585582 <37. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26585582 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lovegrove C AU - Novara G AU - Mottrie A AU - Guru KA AU - Brown M AU - Challacombe B AU - Popert R AU - Raza J AU - Van der Poel H AU - Peabody J AU - Dasgupta P AU - Ahmed K FA - Lovegrove, Catherine FA - Novara, Giacomo FA - Mottrie, Alex FA - Guru, Khurshid A FA - Brown, Matthew FA - Challacombe, Ben FA - Popert, Richard FA - Raza, Johar FA - Van der Poel, Henk FA - Peabody, James FA - Dasgupta, Prokar FA - Ahmed, Kamran IN - Lovegrove, Catherine. King's College London, Guy's Hospital, London, UK. IN - Novara, Giacomo. University of Padua, Padua, Italy. IN - Mottrie, Alex. OLV Clinic, Aalst, Belgium. IN - Guru, Khurshid A. Roswell Park Cancer Institute, Buffalo, NY, USA. IN - Brown, Matthew. Fiona Stanley Hospital, Perth, Australia. IN - Challacombe, Ben. King's College London, Guy's Hospital, London, UK. IN - Popert, Richard. King's College London, Guy's Hospital, London, UK. IN - Raza, Johar. Roswell Park Cancer Institute, Buffalo, NY, USA. IN - Van der Poel, Henk. Netherlands Cancer Institute, Amsterdam, The Netherlands. IN - Peabody, James. Henry Ford Hospital, Detroit, MI, USA. IN - Dasgupta, Prokar. King's College London, Guy's Hospital, London, UK. Electronic address: prokarurol@gmail.com. IN - Ahmed, Kamran. King's College London, Guy's Hospital, London, UK. TI - Structured and Modular Training Pathway for Robot-assisted Radical Prostatectomy (RARP): Validation of the RARP Assessment Score and Learning Curve Assessment. SO - European Urology. 69(3):526-35, 2016 Mar AS - Eur Urol. 69(3):526-35, 2016 Mar NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Australia MH - Clinical Competence MH - Curriculum MH - *Education, Medical, Graduate/mt [Methods] MH - *Educational Measurement/mt [Methods] MH - Educational Status MH - Europe MH - Humans MH - *Learning Curve MH - Linear Models MH - Longitudinal Studies MH - Male MH - Mentors MH - Multivariate Analysis MH - Prospective Studies MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/ed [Education] MH - Reproducibility of Results MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures/ed [Education] MH - *Task Performance and Analysis MH - *Teaching/mt [Methods] MH - United States KW - Assessment; Learning curve; Patient safety; Robot-assisted radical prostatectomy; Training AB - BACKGROUND: Use of robot-assisted radical prostatectomy (RARP) for prostate cancer is increasing. Structured surgical training and objective assessment are critical for outcomes. AB - OBJECTIVE: To develop and validate a modular training and assessment pathway via Healthcare Failure Mode and Effect Analysis (HFMEA) for trainees undertaking RARP and evaluate learning curves (LCs) for procedural steps. AB - DESIGN, SETTING, AND PARTICIPANTS: This multi-institutional (Europe, Australia, and United States) observational prospective study used HFMEA to identify the high-risk steps of RARP. A specialist focus group enabled validation. Fifteen trainees who underwent European Association of Urology robotic surgery curriculum training performed RARP and were assessed by mentors using the tool developed. Results produced LCs for each step. A plateau above score 4 indicated competence. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: We used a modular training and assessment tool (RARP Assessment Score) to evaluate technical skills. LCs were constructed. Multivariable Kruskal-Wallis, Mann-Whitney U, and kappa coefficient analyses were used. AB - RESULTS AND LIMITATIONS: Five surgeons were observed for 42 console hours to map steps of RARP. HFMEA identified 84 failure modes and 46 potential causes with a hazard score >8. Content validation created the RARP Assessment Score: 17 stages and 41 steps. The RARP Assessment Score was acceptable (56.67%), feasible (96.67%), and had educational impact (100%). Fifteen robotic surgery trainees were assessed for 8 mo. In 426 RARP cases (range: 4-79), all procedural steps were attempted by trainees. Trainees were assessed with the RARP Assessment Score by their expert mentors, and LCs for individual steps were plotted. LCs demonstrated plateaus for anterior bladder neck transection (16 cases), posterior bladder neck transection (18 cases), posterior dissection (9 cases), dissection of prostatic pedicle and seminal vesicles (15 cases), and anastomosis (17 cases). Other steps did not plateau during data collection. AB - CONCLUSIONS: The RARP Assessment Score based on HFMEA methodology identified critical steps for focused RARP training and assessed surgeons. LCs demonstrate the experience necessary to reach a level of competence in technical skills to protect patients. AB - PATIENT SUMMARY: We developed a safety and assessment tool to gauge the technical skills of surgeons performing robot-assisted radical prostatectomy. Improvement was monitored, and measures of progress can be used in future to guide mentors when training surgeons to operate safely. AB - Copyright © 2015 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(15)01082-9 DO - https://dx.doi.org/10.1016/j.eururo.2015.10.048 PT - Journal Article PT - Multicenter Study PT - Observational Study PT - Research Support, Non-U.S. Gov't PT - Validation Studies ID - 26585582 [pubmed] ID - S0302-2838(15)01082-9 [pii] ID - 10.1016/j.eururo.2015.10.048 [doi] PP - ppublish PH - 2015/09/28 [received] PH - 2015/10/23 [accepted] GI - No: MR/J006742/1 Organization: *Medical Research Council* Country: United Kingdom Organization: *Department of Health* Country: United Kingdom Organization: *Medical Research Council* Country: United Kingdom LG - English EP - 20151114 DP - 2016 Mar DC - 20160212 EZ - 2015/11/21 06:00 DA - 2016/11/15 06:00 DT - 2015/11/21 06:00 YR - 2016 ED - 20161114 RD - 20161230 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=26585582 <38. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25924029 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ezelsoy M AU - Caynak B AU - Bayram M AU - Oral K AU - Bayramoglu Z AU - Sagbas E AU - Aytekin V AU - Akpinar B FA - Ezelsoy, Mehmet FA - Caynak, Baris FA - Bayram, Muhammed FA - Oral, Kerem FA - Bayramoglu, Zehra FA - Sagbas, Ertan FA - Aytekin, Vedat FA - Akpinar, Belhhan IN - Ezelsoy, Mehmet. Cardiovascular Surgery Department, Istanbul Florence Nightingale Hospital, Istanbul, Turkey. IN - Caynak, Baris. Cardiovascular Surgery Department, Istanbul Bilim University, Istanbul, Turkey. IN - Bayram, Muhammed. Cardiovascular Surgery Department, Istanbul Florence Nightingale Hospital, Istanbul, Turkey. IN - Oral, Kerem. Cardiovascular Surgery Department, Istanbul Florence Nightingale Hospital, Istanbul, Turkey. IN - Bayramoglu, Zehra. Cardiovascular Surgery Department, Istanbul Florence Nightingale Hospital, Istanbul, Turkey. IN - Sagbas, Ertan. Cardiology Department, Istanbul Florence Nightingale Hospital, Istanbul, Turkey. IN - Aytekin, Vedat. Cardiovascular Surgery Department, Istanbul Bilim University, Istanbul, Turkey. IN - Akpinar, Belhhan. Cardiovascular Surgery Department, Istanbul Florence Nightingale Hospital, Istanbul, Turkey. TI - The Comparison between Minimally Invasive Coronary Bypass Grafting Surgery and Conventional Bypass Grafting Surgery in Proximal LAD Lesion. SO - Heart Surgery Forum. 18(2):E042-6, 2015 Apr 28 AS - Heart Surg Forum. 18(2):E042-6, 2015 Apr 28 NJ - The heart surgery forum PI - Journal available in: Electronic PI - Citation processed from: Internet JC - duc, 100891112 IO - Heart Surg Forum SB - Index Medicus CP - United States MH - Coronary Artery Bypass/mt [Methods] MH - *Coronary Artery Bypass/ut [Utilization] MH - *Coronary Artery Disease/ep [Epidemiology] MH - *Coronary Artery Disease/su [Surgery] MH - Female MH - Humans MH - Male MH - Middle Aged MH - Minimally Invasive Surgical Procedures/mt [Methods] MH - *Minimally Invasive Surgical Procedures/ut [Utilization] MH - Operative Time MH - *Postoperative Complications/ep [Epidemiology] MH - Prevalence MH - Retrospective Studies MH - Risk Factors MH - Robotic Surgical Procedures/mt [Methods] MH - *Robotic Surgical Procedures/ut [Utilization] MH - Treatment Outcome MH - Turkey AB - BACKGROUND: Minimally invasive bypass grafting surgery has entered the clincal routine in several centers around the world, with an increasing popularity in the last decade. In our study, we aimed to make a comparison between minimally invasive coronary artery bypass grafting surgery and conventional bypass grafting surgery in isolated proximal left anterior descending artery (LAD) lesions. AB - METHODS: Between January 2004 and December 2011, patients with proximal LAD lesions, who were treated with robotically assisted minimally invasive coronary artery bypass surgery and conventional bypass surgery, were included in the study. In Group 1, coronary bypass with cardiopulmonary bypass and complete sternotomy were applied to 35 patients and in Group 2, robotically assisted minimally invasive bypass surgery was applied to 35 patients. The demographic, preoperative, perioperative, and postoperative data were collected retrospectively. AB - RESULTS: The mean follow-up time of the conventional bypass group was 5.7 +/- 1.7 years, whereas this ratio was 7.3 +/- 1.3 in the robotic group. There was no postoperative transient ischemic attack (TIA), wound infection, mortality, or need for intra-aortic balloon pump (IABP) in any of the patients. In the conventional bypass group, blood transfusion and ventilation time were significantly higher (P < .05) than in the robotic group. The intensive care unit (ICU) stay and hospital stay were remarkably shorter in the robotic group (P < .01). The postoperative pneumonia rate was significantly higher (20%) in the conventional bypass group (P < .01). Postoperative day 1 pain score was higher in the robotic group (P < .05), however, postoperative day 3 pain score in the conventional bypass group was higher (P < .05). Graft patency rate was 88.6% in the conventional bypass group whereas this ratio was 91.4% in the robotic bypass group, which was not clinically significant (P > .05). AB - CONCLUSIONS: In isolated proximal LAD stenosis, robotic assisted minimally invasive coronary artery bypass grafting surgery requires less blood products, is associated with shorter ICU and hospital stay, and lesser pain in the early postoperative period in contrast to conventional surgery. The result of our studies, which showed similarities to the past studies, lead us to recognize the importance of minimally invasive interventions and the need to perform them more frequently in the future. ES - 1522-6662 IL - 1098-3511 DO - https://dx.doi.org/10.1532/hsf.1239 PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article ID - 25924029 [pubmed] PP - epublish PH - 2015/04/14 [received] PH - 2015/04/14 [accepted] LG - English EP - 20150428 DP - 2015 Apr 28 DC - 20150430 EZ - 2015/04/30 06:00 DA - 2016/11/08 06:00 DT - 2015/04/30 06:00 YR - 2015 ED - 20161107 RD - 20161108 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25924029 <39. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25924029 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ezelsoy M AU - Caynak B AU - Bayram M AU - Oral K AU - Bayramoglu Z AU - Sagbas E AU - Aytekin V AU - Akpinar B FA - Ezelsoy, Mehmet FA - Caynak, Baris FA - Bayram, Muhammed FA - Oral, Kerem FA - Bayramoglu, Zehra FA - Sagbas, Ertan FA - Aytekin, Vedat FA - Akpinar, Belhhan IN - Ezelsoy, Mehmet. Cardiovascular Surgery Department, Istanbul Florence Nightingale Hospital, Istanbul, Turkey. IN - Caynak, Baris. Cardiovascular Surgery Department, Istanbul Bilim University, Istanbul, Turkey. IN - Bayram, Muhammed. Cardiovascular Surgery Department, Istanbul Florence Nightingale Hospital, Istanbul, Turkey. IN - Oral, Kerem. Cardiovascular Surgery Department, Istanbul Florence Nightingale Hospital, Istanbul, Turkey. IN - Bayramoglu, Zehra. Cardiovascular Surgery Department, Istanbul Florence Nightingale Hospital, Istanbul, Turkey. IN - Sagbas, Ertan. Cardiology Department, Istanbul Florence Nightingale Hospital, Istanbul, Turkey. IN - Aytekin, Vedat. Cardiovascular Surgery Department, Istanbul Bilim University, Istanbul, Turkey. IN - Akpinar, Belhhan. Cardiovascular Surgery Department, Istanbul Florence Nightingale Hospital, Istanbul, Turkey. TI - The Comparison between Minimally Invasive Coronary Bypass Grafting Surgery and Conventional Bypass Grafting Surgery in Proximal LAD Lesion. SO - Heart Surgery Forum. 18(2):E042-6, 2015 Apr 28 AS - Heart Surg Forum. 18(2):E042-6, 2015 Apr 28 NJ - The heart surgery forum PI - Journal available in: Electronic PI - Citation processed from: Internet JC - duc, 100891112 IO - Heart Surg Forum SB - Index Medicus CP - United States MH - Coronary Artery Bypass/mt [Methods] MH - *Coronary Artery Bypass/ut [Utilization] MH - *Coronary Artery Disease/ep [Epidemiology] MH - *Coronary Artery Disease/su [Surgery] MH - Female MH - Humans MH - Male MH - Middle Aged MH - Minimally Invasive Surgical Procedures/mt [Methods] MH - *Minimally Invasive Surgical Procedures/ut [Utilization] MH - Operative Time MH - *Postoperative Complications/ep [Epidemiology] MH - Prevalence MH - Retrospective Studies MH - Risk Factors MH - Robotic Surgical Procedures/mt [Methods] MH - *Robotic Surgical Procedures/ut [Utilization] MH - Treatment Outcome MH - Turkey AB - BACKGROUND: Minimally invasive bypass grafting surgery has entered the clincal routine in several centers around the world, with an increasing popularity in the last decade. In our study, we aimed to make a comparison between minimally invasive coronary artery bypass grafting surgery and conventional bypass grafting surgery in isolated proximal left anterior descending artery (LAD) lesions. AB - METHODS: Between January 2004 and December 2011, patients with proximal LAD lesions, who were treated with robotically assisted minimally invasive coronary artery bypass surgery and conventional bypass surgery, were included in the study. In Group 1, coronary bypass with cardiopulmonary bypass and complete sternotomy were applied to 35 patients and in Group 2, robotically assisted minimally invasive bypass surgery was applied to 35 patients. The demographic, preoperative, perioperative, and postoperative data were collected retrospectively. AB - RESULTS: The mean follow-up time of the conventional bypass group was 5.7 +/- 1.7 years, whereas this ratio was 7.3 +/- 1.3 in the robotic group. There was no postoperative transient ischemic attack (TIA), wound infection, mortality, or need for intra-aortic balloon pump (IABP) in any of the patients. In the conventional bypass group, blood transfusion and ventilation time were significantly higher (P < .05) than in the robotic group. The intensive care unit (ICU) stay and hospital stay were remarkably shorter in the robotic group (P < .01). The postoperative pneumonia rate was significantly higher (20%) in the conventional bypass group (P < .01). Postoperative day 1 pain score was higher in the robotic group (P < .05), however, postoperative day 3 pain score in the conventional bypass group was higher (P < .05). Graft patency rate was 88.6% in the conventional bypass group whereas this ratio was 91.4% in the robotic bypass group, which was not clinically significant (P > .05). AB - CONCLUSIONS: In isolated proximal LAD stenosis, robotic assisted minimally invasive coronary artery bypass grafting surgery requires less blood products, is associated with shorter ICU and hospital stay, and lesser pain in the early postoperative period in contrast to conventional surgery. The result of our studies, which showed similarities to the past studies, lead us to recognize the importance of minimally invasive interventions and the need to perform them more frequently in the future. ES - 1522-6662 IL - 1098-3511 DO - https://dx.doi.org/10.1532/hsf.1239 PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article ID - 25924029 [pubmed] PP - epublish PH - 2015/04/14 [received] PH - 2015/04/14 [accepted] LG - English EP - 20150428 DP - 2015 Apr 28 DC - 20150430 EZ - 2015/04/30 06:00 DA - 2016/11/08 06:00 DT - 2015/04/30 06:00 YR - 2015 ED - 20161107 RD - 20161230 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=25924029 <40. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26576836 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Whittaker G AU - Aydin A AU - Raison N AU - Kum F AU - Challacombe B AU - Khan MS AU - Dasgupta P AU - Ahmed K FA - Whittaker, George FA - Aydin, Abdullatif FA - Raison, Nicholas FA - Kum, Francesca FA - Challacombe, Ben FA - Khan, Muhammed Shamim FA - Dasgupta, Prokar FA - Ahmed, Kamran IN - Whittaker, George. 1 School of Medical Education, King's College London , London, United Kingdom . IN - Aydin, Abdullatif. 2 MRC Centre for Transplantation, King's College London , London, United Kingdom . IN - Raison, Nicholas. 2 MRC Centre for Transplantation, King's College London , London, United Kingdom . IN - Kum, Francesca. 3 Department of Urology, Guy's and St. Thomas' NHS Foundation Trust , London, United Kingdom . IN - Challacombe, Ben. 3 Department of Urology, Guy's and St. Thomas' NHS Foundation Trust , London, United Kingdom . IN - Khan, Muhammed Shamim. 2 MRC Centre for Transplantation, King's College London , London, United Kingdom . IN - Khan, Muhammed Shamim. 3 Department of Urology, Guy's and St. Thomas' NHS Foundation Trust , London, United Kingdom . IN - Dasgupta, Prokar. 2 MRC Centre for Transplantation, King's College London , London, United Kingdom . IN - Dasgupta, Prokar. 3 Department of Urology, Guy's and St. Thomas' NHS Foundation Trust , London, United Kingdom . IN - Ahmed, Kamran. 2 MRC Centre for Transplantation, King's College London , London, United Kingdom . IN - Ahmed, Kamran. 3 Department of Urology, Guy's and St. Thomas' NHS Foundation Trust , London, United Kingdom . TI - Validation of the RobotiX Mentor Robotic Surgery Simulator. SO - Journal of Endourology. 30(3):338-46, 2016 Mar AS - J Endourol. 30(3):338-46, 2016 Mar NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - *Computer Simulation/st [Standards] MH - Curriculum MH - Humans MH - Learning Curve MH - Middle Aged MH - Prospective Studies MH - Reproducibility of Results MH - *Robotic Surgical Procedures/ed [Education] MH - *Simulation Training/st [Standards] MH - Surveys and Questionnaires MH - United Kingdom MH - *Urologic Surgical Procedures/ed [Education] MH - *Urology/ed [Education] MH - *User-Computer Interface MH - Young Adult AB - OBJECTIVES: To assess face, content, and construct validity of the RobotiX Mentor virtual reality simulator, to assess its acceptability as a robotic surgery training tool and feasibility of its use, and to develop a supplementary training curriculum. AB - SUBJECTS AND METHODS: This prospective, observational, and comparative study recruited novice (n = 20), intermediate (n = 15), and expert (n = 11) robotic surgeons as participants from institutions across the United Kingdom and at the 30th European Association of Urology Annual Meeting. Each participant completed nine surgical tasks across two modules on the simulator, followed by a questionnaire to evaluate subjective realism (face validity), task importance (content validity), feasibility, and acceptability. Outcome measures of novice, intermediate, and expert groups were compared using Mann-Whitney U-tests to assess construct validity. AB - RESULTS: Construct validity was demonstrated in a total of 17/25 performance evaluation metrics (p < 0.001). Experts performed better than intermediates with regard to time taken to complete the first (p = 0.002) and second (p = 0.043) module, number of instrument collisions (p = 0.040), path length (p = .049), number of cuts >2 mm deep (p = 0.033), average distance from suture target (p = 0.015), and number of suture breakages (p = 0.038). Participants determined both the simulator console and psychomotor tasks as highly realistic (mean: 3.7/5) and important for surgical training (4.5/5), with system pedals (4.2/5) and knot tying task (4.6/5) scoring highest, respectively. The simulator was also rated as an acceptable (4.3/5) tool for training and its use highly feasible (4.3/5). AB - CONCLUSION: Construct, face, and content validity was established for the RobotiX Mentor, and feasibility and acceptability of incorporation into surgical training were ascertained. The RobotiX Mentor shows potential as a valuable tool for training and assessment of trainees in robotic skills. Investigation of concurrent and predictive validity is necessary to complete validation, and evaluation of learning curves would provide insight into its value for training. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2015.0620 PT - Comparative Study PT - Journal Article PT - Observational Study PT - Validation Studies ID - 26576836 [pubmed] ID - 10.1089/end.2015.0620 [doi] PP - ppublish GI - No: MR/J006742/1 Organization: *Medical Research Council* Country: United Kingdom LG - English EP - 20160121 DP - 2016 Mar DC - 20160309 EZ - 2015/11/19 06:00 DA - 2016/11/04 06:00 DT - 2015/11/19 06:00 YR - 2016 ED - 20161103 RD - 20161126 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26576836 <41. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26463701 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Martin Garzon OD AU - Azhar RA AU - Brunacci L AU - Ramirez-Troche NE AU - Medina Navarro L AU - Hernandez LC AU - Nunez Bragayrac L AU - Sotelo Noguera RJ FA - Martin Garzon, Oscar Dario FA - Azhar, Raed A FA - Brunacci, Leonardo FA - Ramirez-Troche, Nelson Emilio FA - Medina Navarro, Luis FA - Hernandez, Luis Cesar FA - Nunez Bragayrac, Luciano FA - Sotelo Noguera, Rene Javier IN - Martin Garzon, Oscar Dario. 1 Instituto Medico La Floresta, Centro de Cirugia Robotica Minimamente Invasiva (CIMI) , Caracas, Venezuela . IN - Azhar, Raed A. 2 Department of Urology, King Abdulaziz University , Jeddah, Saudi Arabia . IN - Azhar, Raed A. 3 USC Institute of Urology, Keck School of Medicine, University of Southern California , Los Angeles, California. IN - Brunacci, Leonardo. 1 Instituto Medico La Floresta, Centro de Cirugia Robotica Minimamente Invasiva (CIMI) , Caracas, Venezuela . IN - Ramirez-Troche, Nelson Emilio. 1 Instituto Medico La Floresta, Centro de Cirugia Robotica Minimamente Invasiva (CIMI) , Caracas, Venezuela . IN - Medina Navarro, Luis. 1 Instituto Medico La Floresta, Centro de Cirugia Robotica Minimamente Invasiva (CIMI) , Caracas, Venezuela . IN - Hernandez, Luis Cesar. 1 Instituto Medico La Floresta, Centro de Cirugia Robotica Minimamente Invasiva (CIMI) , Caracas, Venezuela . IN - Nunez Bragayrac, Luciano. 1 Instituto Medico La Floresta, Centro de Cirugia Robotica Minimamente Invasiva (CIMI) , Caracas, Venezuela . IN - Sotelo Noguera, Rene Javier. 1 Instituto Medico La Floresta, Centro de Cirugia Robotica Minimamente Invasiva (CIMI) , Caracas, Venezuela . IN - Sotelo Noguera, Rene Javier. 3 USC Institute of Urology, Keck School of Medicine, University of Southern California , Los Angeles, California. TI - One-Year Outcome Comparison of Laparoscopic, Robotic, and Robotic Intrafascial Simple Prostatectomy for Benign Prostatic Hyperplasia. SO - Journal of Endourology. 30(3):312-8, 2016 Mar AS - J Endourol. 30(3):312-8, 2016 Mar NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adenocarcinoma/bl [Blood] MH - Adenocarcinoma/di [Diagnosis] MH - *Adenocarcinoma/ep [Epidemiology] MH - Aged MH - Comorbidity MH - *Erectile Dysfunction/ep [Epidemiology] MH - Humans MH - Laparoscopy MH - Male MH - Middle Aged MH - Penile Erection MH - *Postoperative Complications/ep [Epidemiology] MH - Prospective Studies MH - Prostate-Specific Antigen/bl [Blood] MH - *Prostatectomy/mt [Methods] MH - Prostatic Hyperplasia/bl [Blood] MH - Prostatic Hyperplasia/ep [Epidemiology] MH - *Prostatic Hyperplasia/su [Surgery] MH - Prostatic Neoplasms/bl [Blood] MH - Prostatic Neoplasms/di [Diagnosis] MH - *Prostatic Neoplasms/ep [Epidemiology] MH - Treatment Outcome AB - OBJECTIVE: To compare preoperative, intraoperative, and postoperative variables at 1, 6, and 12 months after laparoscopic simple prostatectomy (LSP), robotic simple prostatectomy (RSP), and intrafascial robotic simple prostatectomy (IF-RSP). AB - PATIENTS AND METHODS: From January 2003 to November 2014, 315 simple prostatectomies were performed using three techniques, LSP, RSP, and IF-RSP; of the patients who underwent these procedures, 236 met the inclusion criteria for this study. AB - RESULTS: No statistically significant difference (SSD) was found in preoperative or perioperative variables. Of the postoperative variables that were analyzed, an SSD (p > 0.01) in prostate-specific antigen levels was found, with levels of 0.07 +/- 1.1 ng/mL following IF-RSP, and the detection rate of prostate adenocarcinoma (26%) and high-grade prostatic intraepithelial neoplasia (HG-PIN; 12%) was higher for IF-RSP. We also found that lower International Prostate Symptom Scores (IPSS) were associated with LSP, at 4.8 +/- 3.2. Erectile function was reduced in IF-RSP patients in the first 6 months after surgery but was similar in all patient groups at 12 months after surgery; continence and other measured parameters were also similar at 12 months for all three techniques. AB - CONCLUSION: The IF-RSP technique is safe and effective, with results at 1-year follow-up for continence, IPSS, and Sexual Health Inventory for Men scores similar to those for the LSP and RSP techniques. IF-RSP also offers the advantages that it does not require postoperative irrigation, has an increased ability to detect prostate cancer (CA) and HG-PIN, and avoids the risk of future cancer and subsequent reintervention for possible new prostate growth. RN - EC 3-4-21-77 (Prostate-Specific Antigen) ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2015.0218 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 26463701 [pubmed] ID - 10.1089/end.2015.0218 [doi] PP - ppublish LG - English EP - 20151112 DP - 2016 Mar DC - 20160309 EZ - 2015/10/15 06:00 DA - 2016/11/04 06:00 DT - 2015/10/16 06:00 YR - 2016 ED - 20161103 RD - 20161104 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26463701 <42. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26576836 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Whittaker G AU - Aydin A AU - Raison N AU - Kum F AU - Challacombe B AU - Khan MS AU - Dasgupta P AU - Ahmed K FA - Whittaker, George FA - Aydin, Abdullatif FA - Raison, Nicholas FA - Kum, Francesca FA - Challacombe, Ben FA - Khan, Muhammed Shamim FA - Dasgupta, Prokar FA - Ahmed, Kamran IN - Whittaker, George. 1 School of Medical Education, King's College London , London, United Kingdom . IN - Aydin, Abdullatif. 2 MRC Centre for Transplantation, King's College London , London, United Kingdom . IN - Raison, Nicholas. 2 MRC Centre for Transplantation, King's College London , London, United Kingdom . IN - Kum, Francesca. 3 Department of Urology, Guy's and St. Thomas' NHS Foundation Trust , London, United Kingdom . IN - Challacombe, Ben. 3 Department of Urology, Guy's and St. Thomas' NHS Foundation Trust , London, United Kingdom . IN - Khan, Muhammed Shamim. 2 MRC Centre for Transplantation, King's College London , London, United Kingdom . IN - Khan, Muhammed Shamim. 3 Department of Urology, Guy's and St. Thomas' NHS Foundation Trust , London, United Kingdom . IN - Dasgupta, Prokar. 2 MRC Centre for Transplantation, King's College London , London, United Kingdom . IN - Dasgupta, Prokar. 3 Department of Urology, Guy's and St. Thomas' NHS Foundation Trust , London, United Kingdom . IN - Ahmed, Kamran. 2 MRC Centre for Transplantation, King's College London , London, United Kingdom . IN - Ahmed, Kamran. 3 Department of Urology, Guy's and St. Thomas' NHS Foundation Trust , London, United Kingdom . TI - Validation of the RobotiX Mentor Robotic Surgery Simulator. SO - Journal of Endourology. 30(3):338-46, 2016 Mar AS - J Endourol. 30(3):338-46, 2016 Mar NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - *Computer Simulation/st [Standards] MH - Curriculum MH - Humans MH - Learning Curve MH - Middle Aged MH - Prospective Studies MH - Reproducibility of Results MH - *Robotic Surgical Procedures/ed [Education] MH - *Simulation Training/st [Standards] MH - Surveys and Questionnaires MH - United Kingdom MH - *Urologic Surgical Procedures/ed [Education] MH - *Urology/ed [Education] MH - *User-Computer Interface MH - Young Adult AB - OBJECTIVES: To assess face, content, and construct validity of the RobotiX Mentor virtual reality simulator, to assess its acceptability as a robotic surgery training tool and feasibility of its use, and to develop a supplementary training curriculum. AB - SUBJECTS AND METHODS: This prospective, observational, and comparative study recruited novice (n = 20), intermediate (n = 15), and expert (n = 11) robotic surgeons as participants from institutions across the United Kingdom and at the 30th European Association of Urology Annual Meeting. Each participant completed nine surgical tasks across two modules on the simulator, followed by a questionnaire to evaluate subjective realism (face validity), task importance (content validity), feasibility, and acceptability. Outcome measures of novice, intermediate, and expert groups were compared using Mann-Whitney U-tests to assess construct validity. AB - RESULTS: Construct validity was demonstrated in a total of 17/25 performance evaluation metrics (p < 0.001). Experts performed better than intermediates with regard to time taken to complete the first (p = 0.002) and second (p = 0.043) module, number of instrument collisions (p = 0.040), path length (p = .049), number of cuts >2 mm deep (p = 0.033), average distance from suture target (p = 0.015), and number of suture breakages (p = 0.038). Participants determined both the simulator console and psychomotor tasks as highly realistic (mean: 3.7/5) and important for surgical training (4.5/5), with system pedals (4.2/5) and knot tying task (4.6/5) scoring highest, respectively. The simulator was also rated as an acceptable (4.3/5) tool for training and its use highly feasible (4.3/5). AB - CONCLUSION: Construct, face, and content validity was established for the RobotiX Mentor, and feasibility and acceptability of incorporation into surgical training were ascertained. The RobotiX Mentor shows potential as a valuable tool for training and assessment of trainees in robotic skills. Investigation of concurrent and predictive validity is necessary to complete validation, and evaluation of learning curves would provide insight into its value for training. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2015.0620 PT - Comparative Study PT - Journal Article PT - Observational Study PT - Validation Studies ID - 26576836 [pubmed] ID - 10.1089/end.2015.0620 [doi] PP - ppublish GI - No: MR/J006742/1 Organization: *Medical Research Council* Country: United Kingdom LG - English EP - 20160121 DP - 2016 Mar DC - 20160309 EZ - 2015/11/19 06:00 DA - 2016/11/04 06:00 DT - 2015/11/19 06:00 YR - 2016 ED - 20161103 RD - 20170103 UP - 20170103 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=26576836 <43. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26463701 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Martin Garzon OD AU - Azhar RA AU - Brunacci L AU - Ramirez-Troche NE AU - Medina Navarro L AU - Hernandez LC AU - Nunez Bragayrac L AU - Sotelo Noguera RJ FA - Martin Garzon, Oscar Dario FA - Azhar, Raed A FA - Brunacci, Leonardo FA - Ramirez-Troche, Nelson Emilio FA - Medina Navarro, Luis FA - Hernandez, Luis Cesar FA - Nunez Bragayrac, Luciano FA - Sotelo Noguera, Rene Javier IN - Martin Garzon, Oscar Dario. 1 Instituto Medico La Floresta, Centro de Cirugia Robotica Minimamente Invasiva (CIMI) , Caracas, Venezuela . IN - Azhar, Raed A. 2 Department of Urology, King Abdulaziz University , Jeddah, Saudi Arabia . IN - Azhar, Raed A. 3 USC Institute of Urology, Keck School of Medicine, University of Southern California , Los Angeles, California. IN - Brunacci, Leonardo. 1 Instituto Medico La Floresta, Centro de Cirugia Robotica Minimamente Invasiva (CIMI) , Caracas, Venezuela . IN - Ramirez-Troche, Nelson Emilio. 1 Instituto Medico La Floresta, Centro de Cirugia Robotica Minimamente Invasiva (CIMI) , Caracas, Venezuela . IN - Medina Navarro, Luis. 1 Instituto Medico La Floresta, Centro de Cirugia Robotica Minimamente Invasiva (CIMI) , Caracas, Venezuela . IN - Hernandez, Luis Cesar. 1 Instituto Medico La Floresta, Centro de Cirugia Robotica Minimamente Invasiva (CIMI) , Caracas, Venezuela . IN - Nunez Bragayrac, Luciano. 1 Instituto Medico La Floresta, Centro de Cirugia Robotica Minimamente Invasiva (CIMI) , Caracas, Venezuela . IN - Sotelo Noguera, Rene Javier. 1 Instituto Medico La Floresta, Centro de Cirugia Robotica Minimamente Invasiva (CIMI) , Caracas, Venezuela . IN - Sotelo Noguera, Rene Javier. 3 USC Institute of Urology, Keck School of Medicine, University of Southern California , Los Angeles, California. TI - One-Year Outcome Comparison of Laparoscopic, Robotic, and Robotic Intrafascial Simple Prostatectomy for Benign Prostatic Hyperplasia. SO - Journal of Endourology. 30(3):312-8, 2016 Mar AS - J Endourol. 30(3):312-8, 2016 Mar NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adenocarcinoma/bl [Blood] MH - Adenocarcinoma/di [Diagnosis] MH - *Adenocarcinoma/ep [Epidemiology] MH - Aged MH - Comorbidity MH - *Erectile Dysfunction/ep [Epidemiology] MH - Humans MH - Laparoscopy MH - Male MH - Middle Aged MH - Penile Erection MH - *Postoperative Complications/ep [Epidemiology] MH - Prospective Studies MH - Prostate-Specific Antigen/bl [Blood] MH - *Prostatectomy/mt [Methods] MH - Prostatic Hyperplasia/bl [Blood] MH - Prostatic Hyperplasia/ep [Epidemiology] MH - *Prostatic Hyperplasia/su [Surgery] MH - Prostatic Neoplasms/bl [Blood] MH - Prostatic Neoplasms/di [Diagnosis] MH - *Prostatic Neoplasms/ep [Epidemiology] MH - Treatment Outcome AB - OBJECTIVE: To compare preoperative, intraoperative, and postoperative variables at 1, 6, and 12 months after laparoscopic simple prostatectomy (LSP), robotic simple prostatectomy (RSP), and intrafascial robotic simple prostatectomy (IF-RSP). AB - PATIENTS AND METHODS: From January 2003 to November 2014, 315 simple prostatectomies were performed using three techniques, LSP, RSP, and IF-RSP; of the patients who underwent these procedures, 236 met the inclusion criteria for this study. AB - RESULTS: No statistically significant difference (SSD) was found in preoperative or perioperative variables. Of the postoperative variables that were analyzed, an SSD (p > 0.01) in prostate-specific antigen levels was found, with levels of 0.07 +/- 1.1 ng/mL following IF-RSP, and the detection rate of prostate adenocarcinoma (26%) and high-grade prostatic intraepithelial neoplasia (HG-PIN; 12%) was higher for IF-RSP. We also found that lower International Prostate Symptom Scores (IPSS) were associated with LSP, at 4.8 +/- 3.2. Erectile function was reduced in IF-RSP patients in the first 6 months after surgery but was similar in all patient groups at 12 months after surgery; continence and other measured parameters were also similar at 12 months for all three techniques. AB - CONCLUSION: The IF-RSP technique is safe and effective, with results at 1-year follow-up for continence, IPSS, and Sexual Health Inventory for Men scores similar to those for the LSP and RSP techniques. IF-RSP also offers the advantages that it does not require postoperative irrigation, has an increased ability to detect prostate cancer (CA) and HG-PIN, and avoids the risk of future cancer and subsequent reintervention for possible new prostate growth. RN - EC 3-4-21-77 (Prostate-Specific Antigen) ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2015.0218 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 26463701 [pubmed] ID - 10.1089/end.2015.0218 [doi] PP - ppublish LG - English EP - 20151112 DP - 2016 Mar DC - 20160309 EZ - 2015/10/15 06:00 DA - 2016/11/04 06:00 DT - 2015/10/16 06:00 YR - 2016 ED - 20161103 RD - 20161230 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=26463701 <44. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25980699 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Banner D AU - Lear S AU - Kandola D AU - Singer J AU - Horvat D AU - Bates J AU - Ignaszewski A FA - Banner, Davina FA - Lear, Scott FA - Kandola, Daman FA - Singer, Joel FA - Horvat, Dan FA - Bates, Joanna FA - Ignaszewski, Andrew IN - Banner, Davina. School of Nursing, University of Northern British Columbia. IN - Lear, Scott. Faculty of Health Sciences, Simon Fraser University. IN - Kandola, Daman. School of Nursing, University of Northern British Columbia. IN - Singer, Joel. Centre for Health Evaluation and Outcome Sciences, Providence Health Care. IN - Horvat, Dan. School of Nursing, University of Northern British Columbia. IN - Bates, Joanna. Department of Family Medicine, Faculty of Practice, University of British Columbia. IN - Ignaszewski, Andrew. Division of Cardiology, Providence Health Care c Division of Cardiology. TI - The experiences of patients undertaking a 'virtual' cardiac rehabilitation program. SO - Studies in Health Technology & Informatics. 209:9-14, 2015 AS - Stud Health Technol Inform. 209:9-14, 2015 NJ - Studies in health technology and informatics PI - Journal available in: Print PI - Citation processed from: Internet JC - ck1, 9214582 IO - Stud Health Technol Inform SB - Health Technology Assessment Journals CP - Netherlands MH - Aged MH - British Columbia/ep [Epidemiology] MH - Female MH - Health Services Accessibility/sn [Statistics & Numerical Data] MH - *Heart Diseases/ep [Epidemiology] MH - *Heart Diseases/rh [Rehabilitation] MH - Humans MH - Male MH - Middle Aged MH - Patient Compliance MH - *Patient Education as Topic/sn [Statistics & Numerical Data] MH - *Patient Satisfaction/sn [Statistics & Numerical Data] MH - Rural Health Services/ut [Utilization] MH - *Telemedicine/sn [Statistics & Numerical Data] MH - *Therapy, Computer-Assisted/sn [Statistics & Numerical Data] MH - Treatment Outcome MH - User-Computer Interface AB - Cardiac rehabilitation programs (CRP) are medically supervised, multidisciplinary programs that provide secondary prevention aimed at addressing risk factors and improving lifestyle behaviours for patients following an acute cardiac event. CRPs have been demonstrated to be a cost-effective and evidence-based mechanism to improve patient outcomes, but despite the known benefits of these programs, uptake remains poor. Poor attendance has been linked to many factors, but geographical accessibility is a key concern, since many CRPs are limited to hospitals in urban areas. The widespread availability of the Internet has made it possible to provide virtual health services to populations that may have previously been hard to access. This paper examines the qualitative findings from a 16-month mixed methods randomized controlled trial examining the impact of a virtual CRP (vCRP). The vCRP was revealed to be an accessible, appropriate, convenient and effective way to deliver cardiac rehabilitation services, with patients experiencing both clinical improvements and a high level of satisfaction. To understand the experience of patients undertaking the vCRP, semi-structured interviews were undertaken with a purposive sample of 22 participants. An analysis of the qualitative interviews revealed that the vCRP improved participants' access to healthcare professionals, supported them to make healthy choices, and enhanced feelings of accountability due to greater surveillance. Barriers to participation, such as computer literacy, and general perceptions of a vCRP were also examined. Further investigation into the use and long-term effectiveness of virtual programs across a broader range of healthcare settings is warranted, particularly in those with multiple chronic diseases and those located in rural and remote communities. IS - 0926-9630 IL - 0926-9630 PT - Journal Article PT - Randomized Controlled Trial ID - 25980699 [pubmed] PP - ppublish LG - English DP - 2015 DC - 20150518 EZ - 2015/05/19 06:00 DA - 2016/11/01 06:00 DT - 2015/05/20 06:00 YR - 2015 ED - 20161031 RD - 20161101 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25980699 <45. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25980699 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Banner D AU - Lear S AU - Kandola D AU - Singer J AU - Horvat D AU - Bates J AU - Ignaszewski A FA - Banner, Davina FA - Lear, Scott FA - Kandola, Daman FA - Singer, Joel FA - Horvat, Dan FA - Bates, Joanna FA - Ignaszewski, Andrew IN - Banner, Davina. School of Nursing, University of Northern British Columbia. IN - Lear, Scott. Faculty of Health Sciences, Simon Fraser University. IN - Kandola, Daman. School of Nursing, University of Northern British Columbia. IN - Singer, Joel. Centre for Health Evaluation and Outcome Sciences, Providence Health Care. IN - Horvat, Dan. School of Nursing, University of Northern British Columbia. IN - Bates, Joanna. Department of Family Medicine, Faculty of Practice, University of British Columbia. IN - Ignaszewski, Andrew. Division of Cardiology, Providence Health Care c Division of Cardiology. TI - The experiences of patients undertaking a 'virtual' cardiac rehabilitation program. SO - Studies in Health Technology & Informatics. 209:9-14, 2015 AS - Stud Health Technol Inform. 209:9-14, 2015 NJ - Studies in health technology and informatics PI - Journal available in: Print PI - Citation processed from: Internet JC - ck1, 9214582 IO - Stud Health Technol Inform SB - Health Technology Assessment Journals CP - Netherlands MH - Aged MH - British Columbia/ep [Epidemiology] MH - Female MH - Health Services Accessibility/sn [Statistics & Numerical Data] MH - *Heart Diseases/ep [Epidemiology] MH - *Heart Diseases/rh [Rehabilitation] MH - Humans MH - Male MH - Middle Aged MH - Patient Compliance MH - *Patient Education as Topic/sn [Statistics & Numerical Data] MH - *Patient Satisfaction/sn [Statistics & Numerical Data] MH - Rural Health Services/ut [Utilization] MH - *Telemedicine/sn [Statistics & Numerical Data] MH - *Therapy, Computer-Assisted/sn [Statistics & Numerical Data] MH - Treatment Outcome MH - User-Computer Interface AB - Cardiac rehabilitation programs (CRP) are medically supervised, multidisciplinary programs that provide secondary prevention aimed at addressing risk factors and improving lifestyle behaviours for patients following an acute cardiac event. CRPs have been demonstrated to be a cost-effective and evidence-based mechanism to improve patient outcomes, but despite the known benefits of these programs, uptake remains poor. Poor attendance has been linked to many factors, but geographical accessibility is a key concern, since many CRPs are limited to hospitals in urban areas. The widespread availability of the Internet has made it possible to provide virtual health services to populations that may have previously been hard to access. This paper examines the qualitative findings from a 16-month mixed methods randomized controlled trial examining the impact of a virtual CRP (vCRP). The vCRP was revealed to be an accessible, appropriate, convenient and effective way to deliver cardiac rehabilitation services, with patients experiencing both clinical improvements and a high level of satisfaction. To understand the experience of patients undertaking the vCRP, semi-structured interviews were undertaken with a purposive sample of 22 participants. An analysis of the qualitative interviews revealed that the vCRP improved participants' access to healthcare professionals, supported them to make healthy choices, and enhanced feelings of accountability due to greater surveillance. Barriers to participation, such as computer literacy, and general perceptions of a vCRP were also examined. Further investigation into the use and long-term effectiveness of virtual programs across a broader range of healthcare settings is warranted, particularly in those with multiple chronic diseases and those located in rural and remote communities. IS - 0926-9630 IL - 0926-9630 PT - Journal Article PT - Randomized Controlled Trial ID - 25980699 [pubmed] PP - ppublish LG - English DP - 2015 DC - 20150518 EZ - 2015/05/19 06:00 DA - 2016/11/01 06:00 DT - 2015/05/20 06:00 YR - 2015 ED - 20161031 RD - 20161230 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=25980699 <46. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26680752 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Valdis M AU - Chu MW AU - Schlachta CM AU - Kiaii B FA - Valdis, Matthew FA - Chu, Michael W A FA - Schlachta, Christopher M FA - Kiaii, Bob IN - Valdis, Matthew. From the *Division of Cardiac Surgery, and +Division of General Surgery, Department of Surgery, Western University, London Health Sciences Centre, London, Ontario, Canada. TI - Validation of a Novel Virtual Reality Training Curriculum for Robotic Cardiac Surgery: A Randomized Trial. SO - Innovations: Technology & Techniques in Cardiothoracic & Vascular Surgery. 10(6):383-8, 2015 Nov-Dec AS - Innovations. 10(6):383-8, 2015 Nov-Dec NJ - Innovations (Philadelphia, Pa.) PI - Journal available in: Print PI - Citation processed from: Internet JC - 101257528 IO - Innovations (Phila) SB - Index Medicus CP - United States MH - Adult MH - Animals MH - *Cardiac Surgical Procedures/ed [Education] MH - *Cardiac Surgical Procedures/mt [Methods] MH - Clinical Competence MH - *Curriculum MH - Female MH - Humans MH - Internship and Residency MH - Male MH - Mammary Arteries/su [Surgery] MH - Mitral Valve Annuloplasty/mt [Methods] MH - Operative Time MH - *Robotic Surgical Procedures/ed [Education] MH - *Simulation Training/mt [Methods] MH - *User-Computer Interface AB - OBJECTIVE: Robotic cardiac surgery training has relied entirely on classical methods of surgical teaching. We sought to evaluate the impact of a virtual reality (VR) simulation curriculum to improve skill acquisition in robotic cardiac surgery. AB - METHODS: We randomly assigned 20 surgical trainees to undergo a 9-exercise VR curriculum on a robotic surgical simulator or a control group that received no additional training. The trainees were then evaluated in a blinded fashion by assessing their de-identified video recordings of the following: (1) standardized robotic internal thoracic artery harvest and (2) mitral valve annuloplasty performed in porcine models, using a validated time-based scoring system and an objective intraoperative scoring tool. Postintervention assessments were compared to baseline. AB - RESULTS: Trainees randomized to the VR group were faster than the control group for both the internal thoracic artery harvest (957.3 +/- 98.9 vs. 749.1 +/- 171.9; P = 0.004) and mitral annuloplasty (580.4 +/- 14.4 vs. 463.8 +/- 86.4; P < 0.001) and scored significantly higher with the intraoperative scoring tool (22.8 +/- 2.7 vs. 11.0 +/- 4.5; P < 0.001). Additionally, the VR group achieved a proficiency level similar to our experts for both time-based scores (P = 0.624 and P = 0.967), and the intraoperative assessment (P = 0.110), whereas the control group was not able to meet this level of proficiency for any of the primary outcomes. The average duration of training to successfully complete all required tasks was 9.3 hours. AB - CONCLUSIONS: We have demonstrated that a VR simulation curriculum can significantly improve the efficiency and quality of learning in robotic cardiac surgery. Further evaluation of this curriculum is required for its widespread implementation in surgical training (ClinicalTrials.gov, NCT#02357056). ES - 1559-0879 IL - 1556-9845 DO - https://dx.doi.org/10.1097/IMI.0000000000000222 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 26680752 [pubmed] ID - 10.1097/IMI.0000000000000222 [doi] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT02357056 SL - https://clinicaltrials.gov/search/term=NCT02357056 LG - English DP - 2015 Nov-Dec DC - 20151222 EZ - 2015/12/19 06:00 DA - 2016/11/01 06:00 DT - 2015/12/19 06:00 YR - 2015 ED - 20161027 RD - 20161110 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26680752 <47. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26633002 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Balkhy HH AU - Arnsdorf S AU - Krienbring D AU - Urban J FA - Balkhy, Husam H FA - Arnsdorf, Susan FA - Krienbring, Dorothy FA - Urban, John IN - Balkhy, Husam H. From the *Department of Surgery, The University of Chicago Medicine & Biological Sciences, Chicago, IL USA; and +The Wisconsin Heart Hospital/Summit Anesthesia, Milwaukee, WI USA. TI - Liposome Bupivacaine for Postsurgical Analgesia in Patients Undergoing Robotically Assisted Cardiac Surgery. SO - Innovations: Technology & Techniques in Cardiothoracic & Vascular Surgery. 10(6):416-9, 2015 Nov-Dec AS - Innovations. 10(6):416-9, 2015 Nov-Dec NJ - Innovations (Philadelphia, Pa.) PI - Journal available in: Print PI - Citation processed from: Internet JC - 101257528 IO - Innovations (Phila) SB - Index Medicus CP - United States MH - Aged MH - *Analgesia/mt [Methods] MH - Analgesics, Opioid/tu [Therapeutic Use] MH - *Anesthetics, Local/ad [Administration & Dosage] MH - *Bupivacaine/ad [Administration & Dosage] MH - Cardiac Surgical Procedures/ae [Adverse Effects] MH - *Cardiac Surgical Procedures/mt [Methods] MH - Combined Modality Therapy/mt [Methods] MH - Female MH - Humans MH - Liposomes/ad [Administration & Dosage] MH - Male MH - Middle Aged MH - Minimally Invasive Surgical Procedures/ae [Adverse Effects] MH - *Minimally Invasive Surgical Procedures/mt [Methods] MH - *Pain Management/mt [Methods] MH - Retrospective Studies MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures/mt [Methods] AB - OBJECTIVE: Despite the advantages of robotically assisted cardiac surgery over conventional open sternotomy, robotically assisted surgery may be associated with substantial postsurgical pain arising from multiple incisions and access ports. This single-site, retrospective chart review evaluated the impact of liposome bupivacaine compared with bupivacaine HCl on postsurgical pain management in patients undergoing robotically assisted endoscopic cardiac surgery. AB - METHODS: Sequential patient cohorts undergoing robotically assisted cardiac surgery received either 0.25% bupivacaine HCl (100 mg in 40 mL, n = 30) or liposome bupivacaine (266 mg in 20 mL, expanded to 40 mL with 0.9% sterile normal saline, n = 30) intraoperatively via equal-volume infiltration across port sites. Outcome measures, collected from the day of surgery through postoperative day 3, were daily and total use of opioid analgesics (converted to morphine equivalents), pain intensity (11-point numeric rating scale), and incidence of postoperative nausea and vomiting. AB - RESULTS: Median length of hospital stay was 4 days in the liposome bupivacaine group and 3 days in the bupivacaine HCl group. Patients receiving liposome bupivacaine had numerically lower mean pain scores (at six of seven time points), reduced mean opioid consumption, and a reduced incidence of postoperative nausea and vomiting compared with those receiving bupivacaine HCl, although none of the differences reached statistical significance. AB - CONCLUSIONS: Results from this small retrospective, observational study suggest that liposome bupivacaine may improve postsurgical pain relief and reduce postsurgical opioid consumption, in comparison with bupivacaine HCl, in patients undergoing robotically assisted cardiac surgery. Larger prospective studies of liposome bupivacaine in this setting are warranted. RN - 0 (Analgesics, Opioid) RN - 0 (Anesthetics, Local) RN - 0 (Liposomes) RN - Y8335394RO (Bupivacaine) ES - 1559-0879 IL - 1556-9845 DO - https://dx.doi.org/10.1097/IMI.0000000000000190 PT - Journal Article PT - Observational Study PT - Research Support, Non-U.S. Gov't ID - 26633002 [pubmed] ID - 10.1097/IMI.0000000000000190 [doi] PP - ppublish LG - English DP - 2015 Nov-Dec DC - 20151222 EZ - 2015/12/04 06:00 DA - 2016/11/01 06:00 DT - 2015/12/04 06:00 YR - 2015 ED - 20161027 RD - 20161110 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26633002 <48. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26633002 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Balkhy HH AU - Arnsdorf S AU - Krienbring D AU - Urban J FA - Balkhy, Husam H FA - Arnsdorf, Susan FA - Krienbring, Dorothy FA - Urban, John IN - Balkhy, Husam H. From the *Department of Surgery, The University of Chicago Medicine & Biological Sciences, Chicago, IL USA; and +The Wisconsin Heart Hospital/Summit Anesthesia, Milwaukee, WI USA. TI - Liposome Bupivacaine for Postsurgical Analgesia in Patients Undergoing Robotically Assisted Cardiac Surgery. SO - Innovations: Technology & Techniques in Cardiothoracic & Vascular Surgery. 10(6):416-9, 2015 Nov-Dec AS - Innovations. 10(6):416-9, 2015 Nov-Dec NJ - Innovations (Philadelphia, Pa.) PI - Journal available in: Print PI - Citation processed from: Internet JC - 101257528 IO - Innovations (Phila) SB - Index Medicus CP - United States MH - Aged MH - *Analgesia/mt [Methods] MH - Analgesics, Opioid/tu [Therapeutic Use] MH - *Anesthetics, Local/ad [Administration & Dosage] MH - *Bupivacaine/ad [Administration & Dosage] MH - Cardiac Surgical Procedures/ae [Adverse Effects] MH - *Cardiac Surgical Procedures/mt [Methods] MH - Combined Modality Therapy/mt [Methods] MH - Female MH - Humans MH - Liposomes/ad [Administration & Dosage] MH - Male MH - Middle Aged MH - Minimally Invasive Surgical Procedures/ae [Adverse Effects] MH - *Minimally Invasive Surgical Procedures/mt [Methods] MH - *Pain Management/mt [Methods] MH - Retrospective Studies MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures/mt [Methods] AB - OBJECTIVE: Despite the advantages of robotically assisted cardiac surgery over conventional open sternotomy, robotically assisted surgery may be associated with substantial postsurgical pain arising from multiple incisions and access ports. This single-site, retrospective chart review evaluated the impact of liposome bupivacaine compared with bupivacaine HCl on postsurgical pain management in patients undergoing robotically assisted endoscopic cardiac surgery. AB - METHODS: Sequential patient cohorts undergoing robotically assisted cardiac surgery received either 0.25% bupivacaine HCl (100 mg in 40 mL, n = 30) or liposome bupivacaine (266 mg in 20 mL, expanded to 40 mL with 0.9% sterile normal saline, n = 30) intraoperatively via equal-volume infiltration across port sites. Outcome measures, collected from the day of surgery through postoperative day 3, were daily and total use of opioid analgesics (converted to morphine equivalents), pain intensity (11-point numeric rating scale), and incidence of postoperative nausea and vomiting. AB - RESULTS: Median length of hospital stay was 4 days in the liposome bupivacaine group and 3 days in the bupivacaine HCl group. Patients receiving liposome bupivacaine had numerically lower mean pain scores (at six of seven time points), reduced mean opioid consumption, and a reduced incidence of postoperative nausea and vomiting compared with those receiving bupivacaine HCl, although none of the differences reached statistical significance. AB - CONCLUSIONS: Results from this small retrospective, observational study suggest that liposome bupivacaine may improve postsurgical pain relief and reduce postsurgical opioid consumption, in comparison with bupivacaine HCl, in patients undergoing robotically assisted cardiac surgery. Larger prospective studies of liposome bupivacaine in this setting are warranted. RN - 0 (Analgesics, Opioid) RN - 0 (Anesthetics, Local) RN - 0 (Liposomes) RN - Y8335394RO (Bupivacaine) ES - 1559-0879 IL - 1556-9845 DO - https://dx.doi.org/10.1097/IMI.0000000000000190 PT - Journal Article PT - Observational Study PT - Research Support, Non-U.S. Gov't ID - 26633002 [pubmed] ID - 10.1097/IMI.0000000000000190 [doi] PP - ppublish LG - English DP - 2015 Nov-Dec DC - 20151222 EZ - 2015/12/04 06:00 DA - 2016/11/01 06:00 DT - 2015/12/04 06:00 YR - 2015 ED - 20161027 RD - 20161230 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=26633002 <49. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26680752 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Valdis M AU - Chu MW AU - Schlachta CM AU - Kiaii B FA - Valdis, Matthew FA - Chu, Michael W A FA - Schlachta, Christopher M FA - Kiaii, Bob IN - Valdis, Matthew. From the *Division of Cardiac Surgery, and +Division of General Surgery, Department of Surgery, Western University, London Health Sciences Centre, London, Ontario, Canada. TI - Validation of a Novel Virtual Reality Training Curriculum for Robotic Cardiac Surgery: A Randomized Trial. SO - Innovations: Technology & Techniques in Cardiothoracic & Vascular Surgery. 10(6):383-8, 2015 Nov-Dec AS - Innovations. 10(6):383-8, 2015 Nov-Dec NJ - Innovations (Philadelphia, Pa.) PI - Journal available in: Print PI - Citation processed from: Internet JC - 101257528 IO - Innovations (Phila) SB - Index Medicus CP - United States MH - Adult MH - Animals MH - *Cardiac Surgical Procedures/ed [Education] MH - *Cardiac Surgical Procedures/mt [Methods] MH - Clinical Competence MH - *Curriculum MH - Female MH - Humans MH - Internship and Residency MH - Male MH - Mammary Arteries/su [Surgery] MH - Mitral Valve Annuloplasty/mt [Methods] MH - Operative Time MH - *Robotic Surgical Procedures/ed [Education] MH - *Simulation Training/mt [Methods] MH - *User-Computer Interface AB - OBJECTIVE: Robotic cardiac surgery training has relied entirely on classical methods of surgical teaching. We sought to evaluate the impact of a virtual reality (VR) simulation curriculum to improve skill acquisition in robotic cardiac surgery. AB - METHODS: We randomly assigned 20 surgical trainees to undergo a 9-exercise VR curriculum on a robotic surgical simulator or a control group that received no additional training. The trainees were then evaluated in a blinded fashion by assessing their de-identified video recordings of the following: (1) standardized robotic internal thoracic artery harvest and (2) mitral valve annuloplasty performed in porcine models, using a validated time-based scoring system and an objective intraoperative scoring tool. Postintervention assessments were compared to baseline. AB - RESULTS: Trainees randomized to the VR group were faster than the control group for both the internal thoracic artery harvest (957.3 +/- 98.9 vs. 749.1 +/- 171.9; P = 0.004) and mitral annuloplasty (580.4 +/- 14.4 vs. 463.8 +/- 86.4; P < 0.001) and scored significantly higher with the intraoperative scoring tool (22.8 +/- 2.7 vs. 11.0 +/- 4.5; P < 0.001). Additionally, the VR group achieved a proficiency level similar to our experts for both time-based scores (P = 0.624 and P = 0.967), and the intraoperative assessment (P = 0.110), whereas the control group was not able to meet this level of proficiency for any of the primary outcomes. The average duration of training to successfully complete all required tasks was 9.3 hours. AB - CONCLUSIONS: We have demonstrated that a VR simulation curriculum can significantly improve the efficiency and quality of learning in robotic cardiac surgery. Further evaluation of this curriculum is required for its widespread implementation in surgical training (ClinicalTrials.gov, NCT#02357056). ES - 1559-0879 IL - 1556-9845 DO - https://dx.doi.org/10.1097/IMI.0000000000000222 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 26680752 [pubmed] ID - 10.1097/IMI.0000000000000222 [doi] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT02357056 SL - https://clinicaltrials.gov/search/term=NCT02357056 LG - English DP - 2015 Nov-Dec DC - 20151222 EZ - 2015/12/19 06:00 DA - 2016/11/01 06:00 DT - 2015/12/19 06:00 YR - 2015 ED - 20161027 RD - 20161230 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=26680752 <50. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27474375 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Yaxley JW AU - Coughlin GD AU - Chambers SK AU - Occhipinti S AU - Samaratunga H AU - Zajdlewicz L AU - Dunglison N AU - Carter R AU - Williams S AU - Payton DJ AU - Perry-Keene J AU - Lavin MF AU - Gardiner RA FA - Yaxley, John W FA - Coughlin, Geoffrey D FA - Chambers, Suzanne K FA - Occhipinti, Stefano FA - Samaratunga, Hema FA - Zajdlewicz, Leah FA - Dunglison, Nigel FA - Carter, Rob FA - Williams, Scott FA - Payton, Diane J FA - Perry-Keene, Joanna FA - Lavin, Martin F FA - Gardiner, Robert A IN - Yaxley, John W. Department of Urology, Royal Brisbane & Women's Hospital, Brisbane, QLD, Australia. IN - Coughlin, Geoffrey D. Department of Urology, Royal Brisbane & Women's Hospital, Brisbane, QLD, Australia. IN - Chambers, Suzanne K. Menzies Health Institute Queensland, Griffith University, Gold Coast, QLD, Australia; The University of Queensland Centre for Clinical Research, Brisbane, QLD, Australia; Edith Cowan University, Perth, WA, Australia; Cancer Council Queensland, Brisbane, QLD, Australia; Prostate Cancer Foundation of Australia, Sydney, NSW, Australia. IN - Occhipinti, Stefano. Menzies Health Institute Queensland, Griffith University, Gold Coast, QLD, Australia. IN - Samaratunga, Hema. The University of Queensland Centre for Clinical Research, Brisbane, QLD, Australia; Aquesta Specialized Uropathology, Brisbane, QLD, Australia; Princess Alexandra Hospital, Brisbane, QLD, Australia. IN - Zajdlewicz, Leah. Cancer Council Queensland, Brisbane, QLD, Australia. IN - Dunglison, Nigel. Department of Urology, Royal Brisbane & Women's Hospital, Brisbane, QLD, Australia. IN - Carter, Rob. Deakin University, Melbourne, VIC, Australia. IN - Williams, Scott. Peter Macallum Cancer Centre, Melbourne, VIC, Australia. IN - Payton, Diane J. Queensland Pathology, Brisbane, QLD, Australia. IN - Perry-Keene, Joanna. Queensland Pathology, Brisbane, QLD, Australia. IN - Lavin, Martin F. The University of Queensland Centre for Clinical Research, Brisbane, QLD, Australia. IN - Gardiner, Robert A. Department of Urology, Royal Brisbane & Women's Hospital, Brisbane, QLD, Australia; The University of Queensland Centre for Clinical Research, Brisbane, QLD, Australia; Edith Cowan University, Perth, WA, Australia. Electronic address: f.gardiner@uq.edu.au. TI - Robot-assisted laparoscopic prostatectomy versus open radical retropubic prostatectomy: early outcomes from a randomised controlled phase 3 study. CM - Comment in: Lancet. 2016 Sep 10;388(10049):1026 Note: ; PMID: 27628508 CM - Comment in: Lancet. 2016 Sep 10;388(10049):1027-8 Note: ; PMID: 27474377 SO - Lancet. 388(10049):1057-66, 2016 Sep 10 AS - Lancet. 388(10049):1057-66, 2016 Sep 10 NJ - Lancet (London, England) PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 2985213r, l0s, 0053266 IO - Lancet SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - Adult MH - Aged MH - Comorbidity MH - Humans MH - *Laparoscopy MH - Male MH - Middle Aged MH - *Penile Erection MH - Postoperative Complications/et [Etiology] MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/pp [Physiopathology] MH - *Prostatic Neoplasms/su [Surgery] MH - *Quality of Life MH - Queensland MH - *Robotic Surgical Procedures MH - Self Report MH - Treatment Outcome MH - *Urination AB - BACKGROUND: The absence of trial data comparing robot-assisted laparoscopic prostatectomy and open radical retropubic prostatectomy is a crucial knowledge gap in uro-oncology. We aimed to compare these two approaches in terms of functional and oncological outcomes and report the early postoperative outcomes at 12 weeks. AB - METHOD: In this randomised controlled phase 3 study, men who had newly diagnosed clinically localised prostate cancer and who had chosen surgery as their treatment approach, were able to read and speak English, had no previous history of head injury, dementia, or psychiatric illness or no other concurrent cancer, had an estimated life expectancy of 10 years or more, and were aged between 35 years and 70 years were eligible and recruited from the Royal Brisbane and Women's Hospital (Brisbane, QLD). Participants were randomly assigned (1:1) to receive either robot-assisted laparoscopic prostatectomy or radical retropubic prostatectomy. Randomisation was computer generated and occurred in blocks of ten. This was an open trial; however, study investigators involved in data analysis were masked to each patient's condition. Further, a masked central pathologist reviewed the biopsy and radical prostatectomy specimens. Primary outcomes were urinary function (urinary domain of EPIC) and sexual function (sexual domain of EPIC and IIEF) at 6 weeks, 12 weeks, and 24 months and oncological outcome (positive surgical margin status and biochemical and imaging evidence of progression at 24 months). The trial was powered to assess health-related and domain-specific quality of life outcomes over 24 months. We report here the early outcomes at 6 weeks and 12 weeks. The per-protocol populations were included in the primary and safety analyses. This trial was registered with the Australian New Zealand Clinical Trials Registry (ANZCTR), number ACTRN12611000661976. AB - FINDINGS: Between Aug 23, 2010, and Nov 25, 2014, 326 men were enrolled, of whom 163 were randomly assigned to radical retropubic prostatectomy and 163 to robot-assisted laparoscopic prostatectomy. 18 withdrew (12 assigned to radical retropubic prostatectomy and six assigned to robot-assisted laparoscopic prostatectomy); thus, 151 in the radical retropubic prostatectomy group proceeded to surgery and 157 in the robot-assisted laparoscopic prostatectomy group. 121 assigned to radical retropubic prostatectomy completed the 12 week questionnaire versus 131 assigned to robot-assisted laparoscopic prostatectomy. Urinary function scores did not differ significantly between the radical retropubic prostatectomy group and robot-assisted laparoscopic prostatectomy group at 6 weeks post-surgery (74.50 vs 71.10; p=0.09) or 12 weeks post-surgery (83.80 vs 82.50; p=0.48). Sexual function scores did not differ significantly between the radical retropubic prostatectomy group and robot-assisted laparoscopic prostatectomy group at 6 weeks post-surgery (30.70 vs 32.70; p=0.45) or 12 weeks post-surgery (35.00 vs 38.90; p=0.18). Equivalence testing on the difference between the proportion of positive surgical margins between the two groups (15 [10%] in the radical retropubic prostatectomy group vs 23 [15%] in the robot-assisted laparoscopic prostatectomy group) showed that equality between the two techniques could not be established based on a 90% CI with a DELTA of 10%. However, a superiority test showed that the two proportions were not significantly different (p=0.21). 14 patients (9%) in the radical retropubic prostatectomy group versus six (4%) in the robot-assisted laparoscopic prostatectomy group had postoperative complications (p=0.052). 12 (8%) men receiving radical retropubic prostatectomy and three (2%) men receiving robot-assisted laparoscopic prostatectomy experienced intraoperative adverse events. AB - INTERPRETATION: These two techniques yield similar functional outcomes at 12 weeks. Longer term follow-up is needed. In the interim, we encourage patients to choose an experienced surgeon they trust and with whom they have rapport, rather than a specific surgical approach. AB - FUNDING: Cancer Council Queensland. AB - Copyright © 2016 Elsevier Ltd. All rights reserved. ES - 1474-547X IL - 0140-6736 DI - S0140-6736(16)30592-X DO - https://dx.doi.org/10.1016/S0140-6736(16)30592-X PT - Clinical Trial, Phase III PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 27474375 [pubmed] ID - S0140-6736(16)30592-X [pii] ID - 10.1016/S0140-6736(16)30592-X [doi] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/ACTRN12611000661976 SL - https://clinicaltrials.gov/search/term=ACTRN12611000661976 GI - Country: International LG - English EP - 20160726 DP - 2016 Sep 10 DC - 20160916 EZ - 2016/07/31 06:00 DA - 2016/12/03 06:00 DT - 2016/07/31 06:00 YR - 2016 ED - 20161019 RD - 20161203 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=27474375 <51. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27474375 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Yaxley JW AU - Coughlin GD AU - Chambers SK AU - Occhipinti S AU - Samaratunga H AU - Zajdlewicz L AU - Dunglison N AU - Carter R AU - Williams S AU - Payton DJ AU - Perry-Keene J AU - Lavin MF AU - Gardiner RA FA - Yaxley, John W FA - Coughlin, Geoffrey D FA - Chambers, Suzanne K FA - Occhipinti, Stefano FA - Samaratunga, Hema FA - Zajdlewicz, Leah FA - Dunglison, Nigel FA - Carter, Rob FA - Williams, Scott FA - Payton, Diane J FA - Perry-Keene, Joanna FA - Lavin, Martin F FA - Gardiner, Robert A IN - Yaxley, John W. Department of Urology, Royal Brisbane & Women's Hospital, Brisbane, QLD, Australia. IN - Coughlin, Geoffrey D. Department of Urology, Royal Brisbane & Women's Hospital, Brisbane, QLD, Australia. IN - Chambers, Suzanne K. Menzies Health Institute Queensland, Griffith University, Gold Coast, QLD, Australia; The University of Queensland Centre for Clinical Research, Brisbane, QLD, Australia; Edith Cowan University, Perth, WA, Australia; Cancer Council Queensland, Brisbane, QLD, Australia; Prostate Cancer Foundation of Australia, Sydney, NSW, Australia. IN - Occhipinti, Stefano. Menzies Health Institute Queensland, Griffith University, Gold Coast, QLD, Australia. IN - Samaratunga, Hema. The University of Queensland Centre for Clinical Research, Brisbane, QLD, Australia; Aquesta Specialized Uropathology, Brisbane, QLD, Australia; Princess Alexandra Hospital, Brisbane, QLD, Australia. IN - Zajdlewicz, Leah. Cancer Council Queensland, Brisbane, QLD, Australia. IN - Dunglison, Nigel. Department of Urology, Royal Brisbane & Women's Hospital, Brisbane, QLD, Australia. IN - Carter, Rob. Deakin University, Melbourne, VIC, Australia. IN - Williams, Scott. Peter Macallum Cancer Centre, Melbourne, VIC, Australia. IN - Payton, Diane J. Queensland Pathology, Brisbane, QLD, Australia. IN - Perry-Keene, Joanna. Queensland Pathology, Brisbane, QLD, Australia. IN - Lavin, Martin F. The University of Queensland Centre for Clinical Research, Brisbane, QLD, Australia. IN - Gardiner, Robert A. Department of Urology, Royal Brisbane & Women's Hospital, Brisbane, QLD, Australia; The University of Queensland Centre for Clinical Research, Brisbane, QLD, Australia; Edith Cowan University, Perth, WA, Australia. Electronic address: f.gardiner@uq.edu.au. TI - Robot-assisted laparoscopic prostatectomy versus open radical retropubic prostatectomy: early outcomes from a randomised controlled phase 3 study. CM - Comment in: Lancet. 2016 Sep 10;388(10049):1026; PMID: 27628508 CM - Comment in: Lancet. 2016 Sep 10;388(10049):1027-8; PMID: 27474377 CM - Comment in: Ann Transl Med. 2016 Dec;4(23 ):467; PMID: 28090523 SO - Lancet. 388(10049):1057-1066, 2016 Sep 10 AS - Lancet. 388(10049):1057-1066, 2016 Sep 10 NJ - Lancet (London, England) PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 2985213r, l0s, 0053266 IO - Lancet SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - Adult MH - Aged MH - Comorbidity MH - Humans MH - *Laparoscopy MH - Male MH - Middle Aged MH - *Penile Erection MH - Postoperative Complications/et [Etiology] MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/pp [Physiopathology] MH - *Prostatic Neoplasms/su [Surgery] MH - *Quality of Life MH - Queensland MH - *Robotic Surgical Procedures MH - Self Report MH - Treatment Outcome MH - *Urination AB - BACKGROUND: The absence of trial data comparing robot-assisted laparoscopic prostatectomy and open radical retropubic prostatectomy is a crucial knowledge gap in uro-oncology. We aimed to compare these two approaches in terms of functional and oncological outcomes and report the early postoperative outcomes at 12 weeks. AB - METHOD: In this randomised controlled phase 3 study, men who had newly diagnosed clinically localised prostate cancer and who had chosen surgery as their treatment approach, were able to read and speak English, had no previous history of head injury, dementia, or psychiatric illness or no other concurrent cancer, had an estimated life expectancy of 10 years or more, and were aged between 35 years and 70 years were eligible and recruited from the Royal Brisbane and Women's Hospital (Brisbane, QLD). Participants were randomly assigned (1:1) to receive either robot-assisted laparoscopic prostatectomy or radical retropubic prostatectomy. Randomisation was computer generated and occurred in blocks of ten. This was an open trial; however, study investigators involved in data analysis were masked to each patient's condition. Further, a masked central pathologist reviewed the biopsy and radical prostatectomy specimens. Primary outcomes were urinary function (urinary domain of EPIC) and sexual function (sexual domain of EPIC and IIEF) at 6 weeks, 12 weeks, and 24 months and oncological outcome (positive surgical margin status and biochemical and imaging evidence of progression at 24 months). The trial was powered to assess health-related and domain-specific quality of life outcomes over 24 months. We report here the early outcomes at 6 weeks and 12 weeks. The per-protocol populations were included in the primary and safety analyses. This trial was registered with the Australian New Zealand Clinical Trials Registry (ANZCTR), number ACTRN12611000661976. AB - FINDINGS: Between Aug 23, 2010, and Nov 25, 2014, 326 men were enrolled, of whom 163 were randomly assigned to radical retropubic prostatectomy and 163 to robot-assisted laparoscopic prostatectomy. 18 withdrew (12 assigned to radical retropubic prostatectomy and six assigned to robot-assisted laparoscopic prostatectomy); thus, 151 in the radical retropubic prostatectomy group proceeded to surgery and 157 in the robot-assisted laparoscopic prostatectomy group. 121 assigned to radical retropubic prostatectomy completed the 12 week questionnaire versus 131 assigned to robot-assisted laparoscopic prostatectomy. Urinary function scores did not differ significantly between the radical retropubic prostatectomy group and robot-assisted laparoscopic prostatectomy group at 6 weeks post-surgery (74.50 vs 71.10; p=0.09) or 12 weeks post-surgery (83.80 vs 82.50; p=0.48). Sexual function scores did not differ significantly between the radical retropubic prostatectomy group and robot-assisted laparoscopic prostatectomy group at 6 weeks post-surgery (30.70 vs 32.70; p=0.45) or 12 weeks post-surgery (35.00 vs 38.90; p=0.18). Equivalence testing on the difference between the proportion of positive surgical margins between the two groups (15 [10%] in the radical retropubic prostatectomy group vs 23 [15%] in the robot-assisted laparoscopic prostatectomy group) showed that equality between the two techniques could not be established based on a 90% CI with a DELTA of 10%. However, a superiority test showed that the two proportions were not significantly different (p=0.21). 14 patients (9%) in the radical retropubic prostatectomy group versus six (4%) in the robot-assisted laparoscopic prostatectomy group had postoperative complications (p=0.052). 12 (8%) men receiving radical retropubic prostatectomy and three (2%) men receiving robot-assisted laparoscopic prostatectomy experienced intraoperative adverse events. AB - INTERPRETATION: These two techniques yield similar functional outcomes at 12 weeks. Longer term follow-up is needed. In the interim, we encourage patients to choose an experienced surgeon they trust and with whom they have rapport, rather than a specific surgical approach. AB - FUNDING: Cancer Council Queensland. AB - Copyright © 2016 Elsevier Ltd. All rights reserved. ES - 1474-547X IL - 0140-6736 DI - S0140-6736(16)30592-X DO - https://dx.doi.org/10.1016/S0140-6736(16)30592-X PT - Clinical Trial, Phase III PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - S0140-6736(16)30592-X [pii] ID - 10.1016/S0140-6736(16)30592-X [doi] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/ACTRN12611000661976 SL - https://clinicaltrials.gov/search/term=ACTRN12611000661976 GI - Country: International LG - English EP - 20160726 DP - 2016 Sep 10 DC - 20160916 EZ - 2016/07/31 06:00 DA - 2016/12/03 06:00 DT - 2016/07/31 06:00 YR - 2016 ED - 20161019 RD - 20170413 UP - 20170414 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=27474375 <52. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26787177 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Harrop E AU - Kelly J AU - Griffiths G AU - Casbard A AU - Nelson A AU - Published on behalf of the BOLERO Trial Management Group (TMG) FA - Harrop, Emily FA - Kelly, John FA - Griffiths, Gareth FA - Casbard, Angela FA - Nelson, Annmarie FA - Published on behalf of the BOLERO Trial Management Group (TMG) IN - Harrop, Emily. Marie Curie Palliative Care Research Centre, Cardiff University School of Medicine, Division of Population Medicine, 1st Floor Neuadd Meirionydd, Heath Park Way, Cardiff, CF14 4YS, UK. harrope@cardiff.ac.uk. IN - Kelly, John. Division of Surgery and Interventional Science, UCL Medical School, University College London, 74 Huntley Street, London, WC1E 6AU, UK. j.d.kelly@ucl.ac.uk. IN - Griffiths, Gareth. Southampton Clinical Trials Unit, Faculty of Medicine, University of Southampton, Southampton, SO16 6YD, UK. G.O.Griffiths@soton.ac.uk. IN - Casbard, Angela. Wales Cancer Trials Unit, Cardiff University School of Medicine, 6th Floor Neuadd Meirionydd, Heath Park Way, Cardiff, CF14 4YS, UK. CasbardAC@cardiff.ac.uk. IN - Nelson, Annmarie. Marie Curie Palliative Care Research Centre, Cardiff University School of Medicine, Division of Population Medicine, 1st Floor Neuadd Meirionydd, Heath Park Way, Cardiff, CF14 4YS, UK. NelsonA9@cf.ac.uk. TI - Why do patients decline surgical trials? Findings from a qualitative interview study embedded in the Cancer Research UK BOLERO trial (Bladder cancer: Open versus Lapararoscopic or RObotic cystectomy). SO - Trials [Electronic Resource]. 17:35, 2016 Jan 19 AS - Trials. 17:35, 2016 Jan 19 NJ - Trials PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101263253 IO - Trials PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719666 SB - Index Medicus CP - England MH - Adult MH - Aged MH - *Clinical Trials as Topic/px [Psychology] MH - *Cystectomy MH - Female MH - Humans MH - Interviews as Topic MH - *Laparoscopy MH - Male MH - Middle Aged MH - *Patient Selection MH - *Qualitative Research MH - *Robotic Surgical Procedures MH - United Kingdom MH - *Urinary Bladder Neoplasms/su [Surgery] AB - BACKGROUND: Surgical trials have typically experienced recruitment difficulties when compared with other types of oncology trials. Qualitative studies have an important role to play in exploring reasons for low recruitment, although to date few such studies have been carried out that are embedded in surgical trials. The BOLERO trial (Bladder cancer: Open versus Lapararoscopic or RObotic cystectomy) is a study to determine the feasibility of randomisation to open versus laparoscopic access/robotic cystectomy in patients with bladder cancer. We describe the results of a qualitative study embedded within the clinical trial that explored why patients decline randomisation. AB - METHODS: Ten semi-structured interviews with patients who declined randomisation to the clinical trial, and two interviews with recruiting research nurses were conducted. Data were analysed for key themes. AB - RESULTS: The majority of patients declined the trial because they had preferences for a particular treatment arm, and in usual practice could choose which surgical method they would be given. In most cases the robotic option was preferred. Patients described an intuitive 'sense' that favoured the new technology and had carried out their own inquiries, including Internet research and talking with previous patients and friends and family with medical backgrounds. Medical histories and lifestyle considerations also shaped these personalised choices. Of importance too, however, were the messages patients perceived from their clinical encounters. Whilst some patients felt their surgeon favoured the robotic option, others interpreted 'indirect' cues such as the 'established' reputation of the surgeon and surgical method and comments made during clinical assessments. Many patients expressed a wish for greater direction from their surgeon when making these decisions. AB - CONCLUSION: For trials where the 'new technology' is available to patients, there will likely be difficulties with recruitment. Greater attention could be paid to how messages about treatment options and the trial are conveyed across the whole clinical setting. However, if it is too difficult to challenge such messages, then questions should be asked about whether genuine and convincing equipoise can be presented and perceived in such trials. This calls for consideration of whether alternative methods of generating evidence could be used when evaluating surgical techniques which are established and routinely available. AB - TRIAL REGISTRATION: AB - TRIAL REGISTRATION NUMBER: ISRCTN38528926 (11 December 2008). ES - 1745-6215 IL - 1745-6215 DI - 10.1186/s13063-016-1173-z DO - https://dx.doi.org/10.1186/s13063-016-1173-z PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 26787177 [pubmed] ID - 10.1186/s13063-016-1173-z [doi] ID - 10.1186/s13063-016-1173-z [pii] ID - PMC4719666 [pmc] PP - epublish PH - 2015/06/09 [received] PH - 2016/01/12 [accepted] SI - ISRCTN SA - ISRCTN/ISRCTN38528926 SL - https://www.controlled-trials.com/ISRCTN38528926 GI - No: MCCC-FCO-11-C Organization: *Marie Curie* Country: United Kingdom No: CRUK 08/036 Organization: *Cancer Research UK* Country: United Kingdom LG - English EP - 20160119 DP - 2016 Jan 19 DC - 20160120 EZ - 2016/01/21 06:00 DA - 2016/10/12 06:00 DT - 2016/01/21 06:00 YR - 2016 ED - 20161011 RD - 20161126 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26787177 <53. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26787177 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Harrop E AU - Kelly J AU - Griffiths G AU - Casbard A AU - Nelson A AU - Published on behalf of the BOLERO Trial Management Group (TMG) FA - Harrop, Emily FA - Kelly, John FA - Griffiths, Gareth FA - Casbard, Angela FA - Nelson, Annmarie FA - Published on behalf of the BOLERO Trial Management Group (TMG) IN - Harrop, Emily. Marie Curie Palliative Care Research Centre, Cardiff University School of Medicine, Division of Population Medicine, 1st Floor Neuadd Meirionydd, Heath Park Way, Cardiff, CF14 4YS, UK. harrope@cardiff.ac.uk. IN - Kelly, John. Division of Surgery and Interventional Science, UCL Medical School, University College London, 74 Huntley Street, London, WC1E 6AU, UK. j.d.kelly@ucl.ac.uk. IN - Griffiths, Gareth. Southampton Clinical Trials Unit, Faculty of Medicine, University of Southampton, Southampton, SO16 6YD, UK. G.O.Griffiths@soton.ac.uk. IN - Casbard, Angela. Wales Cancer Trials Unit, Cardiff University School of Medicine, 6th Floor Neuadd Meirionydd, Heath Park Way, Cardiff, CF14 4YS, UK. CasbardAC@cardiff.ac.uk. IN - Nelson, Annmarie. Marie Curie Palliative Care Research Centre, Cardiff University School of Medicine, Division of Population Medicine, 1st Floor Neuadd Meirionydd, Heath Park Way, Cardiff, CF14 4YS, UK. NelsonA9@cf.ac.uk. TI - Why do patients decline surgical trials? Findings from a qualitative interview study embedded in the Cancer Research UK BOLERO trial (Bladder cancer: Open versus Lapararoscopic or RObotic cystectomy). SO - Trials [Electronic Resource]. 17:35, 2016 Jan 19 AS - Trials. 17:35, 2016 Jan 19 NJ - Trials PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101263253 IO - Trials PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719666 SB - Index Medicus CP - England MH - Adult MH - Aged MH - *Clinical Trials as Topic/px [Psychology] MH - *Cystectomy MH - Female MH - Humans MH - Interviews as Topic MH - *Laparoscopy MH - Male MH - Middle Aged MH - *Patient Selection MH - *Qualitative Research MH - *Robotic Surgical Procedures MH - United Kingdom MH - *Urinary Bladder Neoplasms/su [Surgery] AB - BACKGROUND: Surgical trials have typically experienced recruitment difficulties when compared with other types of oncology trials. Qualitative studies have an important role to play in exploring reasons for low recruitment, although to date few such studies have been carried out that are embedded in surgical trials. The BOLERO trial (Bladder cancer: Open versus Lapararoscopic or RObotic cystectomy) is a study to determine the feasibility of randomisation to open versus laparoscopic access/robotic cystectomy in patients with bladder cancer. We describe the results of a qualitative study embedded within the clinical trial that explored why patients decline randomisation. AB - METHODS: Ten semi-structured interviews with patients who declined randomisation to the clinical trial, and two interviews with recruiting research nurses were conducted. Data were analysed for key themes. AB - RESULTS: The majority of patients declined the trial because they had preferences for a particular treatment arm, and in usual practice could choose which surgical method they would be given. In most cases the robotic option was preferred. Patients described an intuitive 'sense' that favoured the new technology and had carried out their own inquiries, including Internet research and talking with previous patients and friends and family with medical backgrounds. Medical histories and lifestyle considerations also shaped these personalised choices. Of importance too, however, were the messages patients perceived from their clinical encounters. Whilst some patients felt their surgeon favoured the robotic option, others interpreted 'indirect' cues such as the 'established' reputation of the surgeon and surgical method and comments made during clinical assessments. Many patients expressed a wish for greater direction from their surgeon when making these decisions. AB - CONCLUSION: For trials where the 'new technology' is available to patients, there will likely be difficulties with recruitment. Greater attention could be paid to how messages about treatment options and the trial are conveyed across the whole clinical setting. However, if it is too difficult to challenge such messages, then questions should be asked about whether genuine and convincing equipoise can be presented and perceived in such trials. This calls for consideration of whether alternative methods of generating evidence could be used when evaluating surgical techniques which are established and routinely available. AB - TRIAL REGISTRATION: AB - TRIAL REGISTRATION NUMBER: ISRCTN38528926 (11 December 2008). ES - 1745-6215 IL - 1745-6215 DI - 10.1186/s13063-016-1173-z DO - https://dx.doi.org/10.1186/s13063-016-1173-z PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 26787177 [pubmed] ID - 10.1186/s13063-016-1173-z [doi] ID - 10.1186/s13063-016-1173-z [pii] ID - PMC4719666 [pmc] PP - epublish PH - 2015/06/09 [received] PH - 2016/01/12 [accepted] SI - ISRCTN SA - ISRCTN/ISRCTN38528926 SL - https://www.controlled-trials.com/ISRCTN38528926 GI - No: MCCC-FCO-11-C Organization: *Marie Curie* Country: United Kingdom No: CRUK 08/036 Organization: *Cancer Research UK* Country: United Kingdom LG - English EP - 20160119 DP - 2016 Jan 19 DC - 20160120 EZ - 2016/01/21 06:00 DA - 2016/10/12 06:00 DT - 2016/01/21 06:00 YR - 2016 ED - 20161011 RD - 20170103 UP - 20170103 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=26787177 <54. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26119408 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Zaouter C AU - Imbault J AU - Labrousse L AU - Abdelmoumen Y AU - Coiffic A AU - Colonna G AU - Jansens JL AU - Ouattara A FA - Zaouter, Cedrick FA - Imbault, Julien FA - Labrousse, Louis FA - Abdelmoumen, Youssef FA - Coiffic, Alain FA - Colonna, Giorgio FA - Jansens, Jean-Luc FA - Ouattara, Alexandre IN - Zaouter, Cedrick. CHU de Bordeaux, Service d'Anesthesie-Reanimation II, Bordeaux, France. Electronic address: cedrick.zaouter@gmail.com. IN - Imbault, Julien. CHU de Bordeaux, Service d'Anesthesie-Reanimation II, Bordeaux, France; University Bordeaux, Adaptation Cardiovasculaire a l'ischemie, Pessac, France. IN - Labrousse, Louis. CHU de Bordeaux, Service de Chirurgie Cardiaque et Vasculaire, Bordeaux, France. IN - Abdelmoumen, Youssef. CHU de Bordeaux, Service d'Anesthesie-Reanimation II, Bordeaux, France. IN - Coiffic, Alain. CHU de Bordeaux, Service d'Anesthesie-Reanimation II, Bordeaux, France. IN - Colonna, Giorgio. CHU de Bordeaux, Service de Chirurgie Cardiaque et Vasculaire, Bordeaux, France. IN - Jansens, Jean-Luc. Hopital Erasme Europe Hospitals, Service de Chirurgie Cardiaque, Brussels, Belgium. IN - Ouattara, Alexandre. CHU de Bordeaux, Service d'Anesthesie-Reanimation II, Bordeaux, France; University Bordeaux, Adaptation Cardiovasculaire a l'ischemie, Pessac, France; INSERM U1034, Adaptation cardiovasculaire a l'ischemie, Pessac, France. TI - Association of Robotic Totally Endoscopic Coronary Artery Bypass Graft Surgery Associated With a Preliminary Cardiac Enhanced Recovery After Surgery Program: A Retrospective Analysis. SO - Journal of Cardiothoracic & Vascular Anesthesia. 29(6):1489-97, 2015 Dec AS - J Cardiothorac Vasc Anesth. 29(6):1489-97, 2015 Dec NJ - Journal of cardiothoracic and vascular anesthesia PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - a6i, 9110208 IO - J. Cardiothorac. Vasc. Anesth. SB - Index Medicus CP - United States MH - Aged MH - *Coronary Artery Bypass, Off-Pump/mt [Methods] MH - *Coronary Artery Disease/di [Diagnosis] MH - *Coronary Artery Disease/su [Surgery] MH - *Endoscopy/mt [Methods] MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Recovery of Function MH - Retrospective Studies MH - *Robotic Surgical Procedures/mt [Methods] KW - cardiac anesthesia; enhanced recovery after surgery; mini-invasive surgery; robotic surgery; totally endoscopic coronary artery bypass graft; ultrafast-track anesthesia AB - OBJECTIVES: The robotic totally endoscopic coronary artery bypass graft (TECAB) surgery reduces patients' recovery time. The present trial investigated the feasibility and safety of an initial enhanced recovery after surgery (ERAS) path for patients undergoing robotic beating-heart TECAB and compared it with both conventional surgery and traditional perioperative care. It was hypothesized that the preliminary ERAS pathway associated with a beating-heart TECAB procedure could have a synergistic effect on postoperative patient care. AB - DESIGN: Observational retrospective study. AB - SETTING: University hospital. AB - PARTICIPANTS: Patients scheduled for coronary artery bypass graft and undergoing robotic beating-heart TECAB (n = 38) were compared with those undergoing standard surgery and perioperative care (n = 33). The outcomes were the possibility of tracheal extubation at the end of the surgery and the incidence of postoperative complications. AB - MEASUREMENTS AND MAIN RESULTS: The main comorbidities were similar between the 2 groups. Extubation on the operating table in the TECAB group was possible in all cases without requiring prompt endotracheal tube reinsertion. The proportion of patients transfused was significantly lower in the TECAB group (p = 0.009). In addition, the duration of intensive care unit and hospital stay were reduced significantly by 24 hours and by 4 days, respectively, in the TECAB group compared with the standard group (p< 0.05). AB - CONCLUSIONS: The present results suggested that a program coupling a beating-heart TECAB with a preliminary ERAS path for patients requiring a single coronary revascularization is feasible and safe. This approach could reduce postoperative mechanical ventilation time, transfusion rate, and both intensive care unit and hospital stay. AB - Copyright © 2015 Elsevier Inc. All rights reserved. ES - 1532-8422 IL - 1053-0770 DI - S1053-0770(15)00129-9 DO - https://dx.doi.org/10.1053/j.jvca.2015.03.003 PT - Journal Article PT - Observational Study PT - Research Support, Non-U.S. Gov't ID - 26119408 [pubmed] ID - S1053-0770(15)00129-9 [pii] ID - 10.1053/j.jvca.2015.03.003 [doi] PP - ppublish PH - 2015/01/09 [received] LG - English EP - 20150305 DP - 2015 Dec DC - 20151226 EZ - 2015/06/30 06:00 DA - 2016/10/07 06:00 DT - 2015/06/30 06:00 YR - 2015 ED - 20161005 RD - 20161110 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26119408 <55. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26119408 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Zaouter C AU - Imbault J AU - Labrousse L AU - Abdelmoumen Y AU - Coiffic A AU - Colonna G AU - Jansens JL AU - Ouattara A FA - Zaouter, Cedrick FA - Imbault, Julien FA - Labrousse, Louis FA - Abdelmoumen, Youssef FA - Coiffic, Alain FA - Colonna, Giorgio FA - Jansens, Jean-Luc FA - Ouattara, Alexandre IN - Zaouter, Cedrick. CHU de Bordeaux, Service d'Anesthesie-Reanimation II, Bordeaux, France. Electronic address: cedrick.zaouter@gmail.com. IN - Imbault, Julien. CHU de Bordeaux, Service d'Anesthesie-Reanimation II, Bordeaux, France; University Bordeaux, Adaptation Cardiovasculaire a l'ischemie, Pessac, France. IN - Labrousse, Louis. CHU de Bordeaux, Service de Chirurgie Cardiaque et Vasculaire, Bordeaux, France. IN - Abdelmoumen, Youssef. CHU de Bordeaux, Service d'Anesthesie-Reanimation II, Bordeaux, France. IN - Coiffic, Alain. CHU de Bordeaux, Service d'Anesthesie-Reanimation II, Bordeaux, France. IN - Colonna, Giorgio. CHU de Bordeaux, Service de Chirurgie Cardiaque et Vasculaire, Bordeaux, France. IN - Jansens, Jean-Luc. Hopital Erasme Europe Hospitals, Service de Chirurgie Cardiaque, Brussels, Belgium. IN - Ouattara, Alexandre. CHU de Bordeaux, Service d'Anesthesie-Reanimation II, Bordeaux, France; University Bordeaux, Adaptation Cardiovasculaire a l'ischemie, Pessac, France; INSERM U1034, Adaptation cardiovasculaire a l'ischemie, Pessac, France. TI - Association of Robotic Totally Endoscopic Coronary Artery Bypass Graft Surgery Associated With a Preliminary Cardiac Enhanced Recovery After Surgery Program: A Retrospective Analysis. SO - Journal of Cardiothoracic & Vascular Anesthesia. 29(6):1489-97, 2015 Dec AS - J Cardiothorac Vasc Anesth. 29(6):1489-97, 2015 Dec NJ - Journal of cardiothoracic and vascular anesthesia PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - a6i, 9110208 IO - J. Cardiothorac. Vasc. Anesth. SB - Index Medicus CP - United States MH - Aged MH - *Coronary Artery Bypass, Off-Pump/mt [Methods] MH - *Coronary Artery Disease/di [Diagnosis] MH - *Coronary Artery Disease/su [Surgery] MH - *Endoscopy/mt [Methods] MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Recovery of Function MH - Retrospective Studies MH - *Robotic Surgical Procedures/mt [Methods] KW - cardiac anesthesia; enhanced recovery after surgery; mini-invasive surgery; robotic surgery; totally endoscopic coronary artery bypass graft; ultrafast-track anesthesia AB - OBJECTIVES: The robotic totally endoscopic coronary artery bypass graft (TECAB) surgery reduces patients' recovery time. The present trial investigated the feasibility and safety of an initial enhanced recovery after surgery (ERAS) path for patients undergoing robotic beating-heart TECAB and compared it with both conventional surgery and traditional perioperative care. It was hypothesized that the preliminary ERAS pathway associated with a beating-heart TECAB procedure could have a synergistic effect on postoperative patient care. AB - DESIGN: Observational retrospective study. AB - SETTING: University hospital. AB - PARTICIPANTS: Patients scheduled for coronary artery bypass graft and undergoing robotic beating-heart TECAB (n = 38) were compared with those undergoing standard surgery and perioperative care (n = 33). The outcomes were the possibility of tracheal extubation at the end of the surgery and the incidence of postoperative complications. AB - MEASUREMENTS AND MAIN RESULTS: The main comorbidities were similar between the 2 groups. Extubation on the operating table in the TECAB group was possible in all cases without requiring prompt endotracheal tube reinsertion. The proportion of patients transfused was significantly lower in the TECAB group (p = 0.009). In addition, the duration of intensive care unit and hospital stay were reduced significantly by 24 hours and by 4 days, respectively, in the TECAB group compared with the standard group (p< 0.05). AB - CONCLUSIONS: The present results suggested that a program coupling a beating-heart TECAB with a preliminary ERAS path for patients requiring a single coronary revascularization is feasible and safe. This approach could reduce postoperative mechanical ventilation time, transfusion rate, and both intensive care unit and hospital stay. AB - Copyright © 2015 Elsevier Inc. All rights reserved. ES - 1532-8422 IL - 1053-0770 DI - S1053-0770(15)00129-9 DO - https://dx.doi.org/10.1053/j.jvca.2015.03.003 PT - Journal Article PT - Observational Study ID - 26119408 [pubmed] ID - S1053-0770(15)00129-9 [pii] ID - 10.1053/j.jvca.2015.03.003 [doi] PP - ppublish PH - 2015/01/09 [received] LG - English EP - 20150305 DP - 2015 Dec DC - 20151226 EZ - 2015/06/30 06:00 DA - 2016/10/07 06:00 DT - 2015/06/30 06:00 YR - 2015 ED - 20161005 RD - 20161230 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=26119408 <56. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25344939 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Graneli C AU - Kockum CC AU - Arnbjornsson E AU - Anderberg M FA - Graneli, Christina FA - Kockum, Christina Clementson FA - Arnbjornsson, Einar FA - Anderberg, Magnus IN - Graneli, Christina. Department of Pediatric Surgery, Skane University Hospital, Lund, Sweden. IN - Kockum, Christina Clementson. Department of Pediatric Surgery, Skane University Hospital, Lund, Sweden. IN - Arnbjornsson, Einar. Department of Pediatric Surgery, Skane University Hospital, Lund, Sweden. IN - Anderberg, Magnus. Department of Pediatric Surgery, Skane University Hospital, Lund, Sweden. TI - Outcome after Computer-Assisted (Robotic) Nissen Fundoplication in Children Measured as Pre- and Postoperative Acid Reducing and Asthma Medications Use. SO - European Journal of Pediatric Surgery. 25(6):532-6, 2015 Dec AS - Eur J Pediatr Surg. 25(6):532-6, 2015 Dec NJ - European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - azo, 9105263 IO - Eur J Pediatr Surg SB - Index Medicus CP - United States MH - Adolescent MH - *Antacids/tu [Therapeutic Use] MH - *Anti-Asthmatic Agents/tu [Therapeutic Use] MH - Asthma/co [Complications] MH - *Asthma/dt [Drug Therapy] MH - Child MH - Child, Preschool MH - Combined Modality Therapy MH - Female MH - Follow-Up Studies MH - *Fundoplication/mt [Methods] MH - Gastroesophageal Reflux/co [Complications] MH - Gastroesophageal Reflux/dt [Drug Therapy] MH - *Gastroesophageal Reflux/su [Surgery] MH - Humans MH - Infant MH - Male MH - Prospective Studies MH - *Robotic Surgical Procedures/mt [Methods] MH - Treatment Outcome AB - PURPOSE: This study aims to report the clinical outcome of computer-assisted fundoplication (CAF) in children. AB - METHODS: As our center changed policy to using computer-assisted surgery only, a prospectively studied cohort of 40 children underwent CAF, during the period from January 2006 through May 2013. The collected data include patient demographics and postoperative complications as well as medication, 24-hour pH measurements and DeMeester scores before and after surgery. AB - RESULTS: In the studied group, the median percentage of the duration of the 24-hour pH<4 decreased postoperatively from 11 (range, 5-39) to 1% (range, 0-12) (p<0.001); the DeMeester score decreased from 40 (range, 17-137) to 5 (range, 1-42) (p<0.001). All 40 patients required antireflux medication before the fundoplication. This number decreased significantly to 8 (20%) after the fundoplication (p<0.001). Before the fundoplication, 22 children (55%) were using asthma medication and 12 (30%) after the fundoplication (p=0.04). AB - CONCLUSIONS: The CAF significantly reduced the acid reflux from the stomach to the esophagus and the use of antireflux as well as asthma medication during the median observation period of 5 years. The evidence of advantages compared with conventional laparoscopic fundoplication remain to be confirmed. AB - Copyright Georg Thieme Verlag KG Stuttgart . New York. RN - 0 (Antacids) RN - 0 (Anti-Asthmatic Agents) ES - 1439-359X IL - 0939-7248 DO - https://dx.doi.org/10.1055/s-0034-1387950 PT - Clinical Trial PT - Journal Article ID - 25344939 [pubmed] ID - 10.1055/s-0034-1387950 [doi] PP - ppublish LG - English EP - 20141026 DP - 2015 Dec DC - 20151231 EZ - 2014/10/27 06:00 DA - 2016/09/27 06:00 DT - 2014/10/27 06:00 YR - 2015 ED - 20160926 RD - 20151231 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25344939 <57. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26531197 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kiely DJ AU - Gotlieb WH AU - Lau S AU - Zeng X AU - Samouelian V AU - Ramanakumar AV AU - Zakrzewski H AU - Brin S AU - Fraser SA AU - Korsieporn P AU - Drudi L AU - Press JZ FA - Kiely, Daniel J FA - Gotlieb, Walter H FA - Lau, Susie FA - Zeng, Xing FA - Samouelian, Vanessa FA - Ramanakumar, Agnihotram V FA - Zakrzewski, Helena FA - Brin, Sonya FA - Fraser, Shannon A FA - Korsieporn, Pira FA - Drudi, Laura FA - Press, Joshua Z IN - Kiely, Daniel J. Experimental Surgery, McGill University, Montreal, Canada. danieljameskiely@gmail.com. IN - Kiely, Daniel J. Gynecologic Oncology, University of Montreal, Montreal, Canada. danieljameskiely@gmail.com. IN - Gotlieb, Walter H. Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, Canada. IN - Lau, Susie. Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, Canada. IN - Zeng, Xing. Gynecologic Oncology, Royal Victoria Hospital, McGill University, Montreal, Canada. IN - Samouelian, Vanessa. Gynecologic Oncology, University of Montreal, Montreal, Canada. IN - Ramanakumar, Agnihotram V. Epidemiology, McGill University, Montreal, Canada. IN - Zakrzewski, Helena. Experimental Surgery, McGill University, Montreal, Canada. IN - Brin, Sonya. Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, Canada. IN - Fraser, Shannon A. General Surgery, Jewish General Hospital, McGill University, Montreal, Canada. IN - Korsieporn, Pira. Obstetrics and Gynecology, McGill University, Montreal, Canada. IN - Drudi, Laura. Vascular Surgery, McGill University, Montreal, Canada. IN - Press, Joshua Z. Division of Oncology and Pelvic Surgery, Pacific Gynecology Specialists, Seattle, USA. TI - Virtual reality robotic surgery simulation curriculum to teach robotic suturing: a randomized controlled trial. SO - Journal of Robotic Surgery. 9(3):179-86, 2015 Sep AS - J. robot. surg.. 9(3):179-86, 2015 Sep NJ - Journal of robotic surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101300401 IO - J Robot Surg SB - Index Medicus CP - England MH - Adult MH - Equipment Design MH - Humans MH - Middle Aged MH - *Robotic Surgical Procedures/ed [Education] MH - *Robotic Surgical Procedures/is [Instrumentation] MH - *Surgeons/ed [Education] MH - *Suture Techniques/ed [Education] MH - *Suture Techniques/is [Instrumentation] MH - User-Computer Interface KW - Computer simulation; Graduate medical education; Operative surgical procedures; Patient simulation; Randomized controlled trial; Robotics AB - The objective of this randomized, controlled trial was to assess whether voluntary participation in a proctored, proficiency-based, virtual reality robotic suturing curriculum using the da Vinci() Skills SimulatorTM improves robotic suturing performance. Residents and attending surgeons were randomized to participation or non-participation during a 5 week training curriculum. Robotic suturing skills were evaluated before and after training using an inanimate vaginal cuff model, which participants sutured for 10 min using the da Vinci() Surgical System. Performances were videotaped, anonymized, and subsequently graded independently by three robotic surgeons. 27 participants were randomized. 23 of the 27 completed both the pre- and post-test, 13 in the training group and 10 in the control group. Mean training time in the intervention group was 238 +/- 136 min (SD) over the 5 weeks. The primary outcome (improvement in GOALS+ score) and the secondary outcomes (improvement in GEARS, total knots, satisfactory knots, and the virtual reality suture sponge 1 task) were significantly greater in the training group than the control group in unadjusted analysis. After adjusting for lower baseline scores in the training group, improvement in the suture sponge 1 task remained significantly greater in the training group and a trend was demonstrated to greater improvement in the training group for the GOALS+ score, GEARS score, total knots, and satisfactory knots. ES - 1863-2491 IL - 1863-2483 DI - 10.1007/s11701-015-0513-4 DO - https://dx.doi.org/10.1007/s11701-015-0513-4 PT - Journal Article PT - Randomized Controlled Trial ID - 26531197 [pubmed] ID - 10.1007/s11701-015-0513-4 [doi] ID - 10.1007/s11701-015-0513-4 [pii] PP - ppublish PH - 2015/03/06 [received] PH - 2015/04/28 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01811095 SL - https://clinicaltrials.gov/search/term=NCT01811095 LG - English EP - 20150516 DP - 2015 Sep DC - 20151104 EZ - 2015/11/05 06:00 DA - 2016/09/24 06:00 DT - 2015/11/05 06:00 YR - 2015 ED - 20160923 RD - 20151104 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26531197 <58. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25792149 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Mearini L AU - Nunzi E AU - Ferri C AU - Bellezza G AU - Lolli C AU - Porrozzi C AU - Porena M FA - Mearini, Luigi FA - Nunzi, Elisabetta FA - Ferri, Carla FA - Bellezza, Guido FA - Lolli, Carolina FA - Porrozzi, Carlo FA - Porena, Massimo IN - Mearini, Luigi. Department of Urology, University of Perugia, Perugia, Italy. TI - Use of the Prostate Health Index for the Detection of Aggressive Prostate Cancer at Radical Prostatectomy. SO - Urologia Internationalis. 95(4):390-9, 2015 AS - Urol Int. 95(4):390-9, 2015 NJ - Urologia internationalis PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - wri, 0417373 IO - Urol. Int. SB - Index Medicus CP - Switzerland MH - Aged MH - Biopsy MH - Follow-Up Studies MH - *Health Status MH - Humans MH - Male MH - Middle Aged MH - Neoplasm Grading MH - Predictive Value of Tests MH - Prognosis MH - Prospective Studies MH - *Prostate-Specific Antigen/me [Metabolism] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/me [Metabolism] MH - *Prostatic Neoplasms/pa [Pathology] MH - Prostatic Neoplasms/su [Surgery] MH - ROC Curve MH - Severity of Illness Index MH - *Tumor Burden AB - INTRODUCTION: In current study, we compared the accuracy of the PSA isoform p2PSA and its derivatives, the percentage of p2PSA to free PSA (%p2PSA) and the Prostate Health Index (PHI) in the detection of prostate cancer (PC) characteristics at the xFB01;nal pathology with respect to reference standards. AB - MATERIALS AND METHODS: This was an observational prospective study evaluating 43 consecutive PC patients treated with laparoscopic/robotic radical prostatectomy (RP). Logistic regression models were fitted to test the predictors of pT3 stage, pathologic Gleason score > 8 or Gleason score upgrading, margin status, lymph node invasion, and the presence of high-risk disease (pT3 disease and/or Gleason score > 8 and/or positive lymph node). The comparative base model included tPSA, clinical stage, biopsy Gleason score, and percentage of positive core. AB - RESULTS: Seventeen patients (39.5%) were affected by pT3 disease or had a pathologic Gleason score > 8; positive margins were detected in 12 patients (27.9%), lymph node invasion was found in 2 patients (4.7%), and 15 patients (34.8%) harbored high-risk disease. In the univariate analysis, p2PSA, %p2PSA, and PHI were significant predictors of pT3 disease, pathologic Gleason score, and the presence of high-risk disease (all p < 0.05), whereas only PHI was an independent predictor of pT3 disease, margin status, and presence of high-risk disease, increasing the accuracy of a base multivariable model by 6.3% (p < 0.05) and 4.2% (p < 0.05) for the prediction of pT3 and high-risk disease, respectively. AB - CONCLUSIONS: p2PSA and its derivatives, primarily PHI, were significant predictors of unfavorable PC characteristics as detected at the xFB01;nal pathology, thus improving the clinical performance of standard prognostic factors for aggressive disease. AB - Copyright © 2015 S. Karger AG, Basel. RN - EC 3-4-21-77 (Prostate-Specific Antigen) ES - 1423-0399 IL - 0042-1138 DI - 000379758 DO - https://dx.doi.org/10.1159/000379758 PT - Journal Article PT - Observational Study ID - 25792149 [pubmed] ID - 000379758 [pii] ID - 10.1159/000379758 [doi] PP - ppublish PH - 2015/01/21 [received] PH - 2015/02/05 [accepted] LG - English EP - 20150317 DP - 2015 DC - 20151215 EZ - 2015/03/21 06:00 DA - 2016/09/22 06:00 DT - 2015/03/21 06:00 YR - 2015 ED - 20160920 RD - 20151215 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25792149 <59. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25484977 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - PubMed-not-MEDLINE AU - Draaisma WA AU - Nieuwenhuis DH AU - Janssen LW AU - Broeders IA FA - Draaisma, Werner A FA - Nieuwenhuis, Dorothee H FA - Janssen, Lucas W M FA - Broeders, Ivo A M J IN - Draaisma, Werner A. Department of Surgery, University Medical Centre Utrecht, Heidelberglaan 100, H.P. G04.228, P. O. Box 85500, 3508 GA Utrecht, The Netherlands. IN - Nieuwenhuis, Dorothee H. Department of Surgery, University Medical Centre Utrecht, Heidelberglaan 100, H.P. G04.228, P. O. Box 85500, 3508 GA Utrecht, The Netherlands. IN - Janssen, Lucas W M. Department of Surgery, University Medical Centre Utrecht, Heidelberglaan 100, H.P. G04.228, P. O. Box 85500, 3508 GA Utrecht, The Netherlands. IN - Broeders, Ivo A M J. Department of Surgery, University Medical Centre Utrecht, Heidelberglaan 100, H.P. G04.228, P. O. Box 85500, 3508 GA Utrecht, The Netherlands. TI - Robot-assisted laparoscopic rectovaginopexy for rectal prolapse: a prospective cohort study on feasibility and safety. SO - Journal of Robotic Surgery. 1(4):273-7, 2008 AS - J. robot. surg.. 1(4):273-7, 2008 NJ - Journal of robotic surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Print JC - 101300401 IO - J Robot Surg PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247452 CP - England KW - Laparoscopy; Rectal prolapse; Rectopexy; Rectovaginopexy; Robot; Robotic surgery AB - Robotic systems may be particularly supportive for procedures requiring careful pelvic dissection and suturing in the Douglas pouch, as in surgery for rectal prolapse. Studies reporting robot-assisted laparoscopic rectovaginopexy for rectal prolapse, however, are scarce. This prospective cohort study evaluated the outcome of this technique up to one year after surgery. From January 2005 to June 2006, 15 consecutive patients with a rectal prolapse, either with or without a concomitant rectocele or enterocele, underwent robot-assisted laparoscopic rectovaginopexy with support of the da Vinci robotic system. A prospective cohort study was performed on operating times, blood loss, intra-operative and post-operative complications, and outcome at a minimum of one year after surgery. Median age at time of operation was 62 years (33-72) and median body mass index 24.9 (20.9-33.9). Median robot set-up time was 10 min (3-15) and median skin-to-skin operating time was 160 min (120-180). No conversions to open surgery were necessary. No in-hospital complications occurred and there was no mortality. Median hospital stay was four days (2-9). During one year follow-up, two patients needed surgical reintervention. One patient was operated for recurrent enterocele and rectocele one week after surgery. In another patient an incisional hernia at the camera port occurred three months after surgery. At one year after surgery, 87% of patients claimed to be satisfied with their postoperative result. Robot-assisted laparoscopic rectovaginopexy proved to be an effective technique with favourable outcomes in most patients in this prospective series. The operating team experienced the support of the robotic system as beneficial, especially during the dissection of the rectovaginal plane and suturing in the Douglas pouch. IS - 1863-2483 IL - 1863-2483 DI - 53 DO - https://dx.doi.org/10.1007/s11701-007-0053-7 PT - Journal Article ID - 25484977 [pubmed] ID - 10.1007/s11701-007-0053-7 [doi] ID - 53 [pii] ID - PMC4247452 [pmc] PP - ppublish PH - 2007/09/14 [received] PH - 2007/12/05 [accepted] LG - English EP - 20080104 DP - 2008 DC - 20160917 EZ - 2014/12/09 06:00 DA - 2008/01/01 00:01 DT - 2008/01/01 00:00 YR - 2008 ED - 20160920 RD - 20160919 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=25484977 <60. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27628468 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - PubMed-not-MEDLINE AU - Lai EC AU - Tang CN AU - Li MK FA - Lai, Eric C H FA - Tang, Chung Ngai FA - Li, Michael K W IN - Lai, Eric C H. Department of Surgery, Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Road, Chai Wan, Hong Kong SAR, China. ericlai@alumni.cuhk.edu.hk. IN - Tang, Chung Ngai. Department of Surgery, Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Road, Chai Wan, Hong Kong SAR, China. IN - Li, Michael K W. Department of Surgery, Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Road, Chai Wan, Hong Kong SAR, China. TI - Conventional laparoscopic and robot-assisted laparoscopic liver resection for benign and malignant pathologies: a cohort study. SO - Journal of Robotic Surgery. 6(4):295-300, 2012 Dec AS - J. robot. surg.. 6(4):295-300, 2012 Dec NJ - Journal of robotic surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Print JC - 101300401 IO - J Robot Surg CP - England KW - Hepatocelluar carcinoma; Laparoscopy; Liver neoplasm; Liver resection; Robotic surgery AB - The aim of our study was to evaluate different minimally invasive surgical approaches for liver resection in a tertiary surgical center. The study cohort comprised 104 consecutive patients who underwent total laparoscopic liver resection (n = 17), hand-assisted laparoscopic liver resection (n = 55), or robot-assisted laparoscopic liver resection (n = 32) in our center between October 1998 and January 2011. Surgical complications, postoperative course, disease-free survival, and overall survival for malignancy were assessed. These 104 resections were performed on 55 men and 49 women with a mean age of 60.4 years; 43.3% of patients had liver cirrhosis. The liver pathologies comprised malignant tumors (64.4%) and benign lesions (35.6%). The most common laparoscopic liver resection was left lateral sectionectomy (53.9%), wedge resection (26.9%), segmentectomy (13.5%), right hepatectomy (3.8%), and left hepatectomy (1.9%). Conversion from laparoscopy to open approach and from laparoscopy to hand-assisted approach occurred in 1.9 and 1% of the cases, respectively. Overall mortality was 0%, and morbidity was 17.3%. The median follow-up period was 24 months. The 5-year overall survival for hepatocellular carcinoma (HCC) was 52%, and the 3-year overall survival for colorectal liver metastasis was 88%. Based on these results, we conclude that laparoscopic liver resection is feasible and safe in appropriately selected patients. In our patient cohort, it was associated with a low complications rate and favorable survival outcome. IS - 1863-2483 IL - 1863-2483 DI - 10.1007/s11701-011-0311-6 DO - https://dx.doi.org/10.1007/s11701-011-0311-6 PT - Journal Article ID - 27628468 [pubmed] ID - 10.1007/s11701-011-0311-6 [doi] ID - 10.1007/s11701-011-0311-6 [pii] PP - ppublish PH - 2011/06/08 [received] PH - 2011/08/25 [accepted] LG - English EP - 20110918 DP - 2012 Dec DC - 20160916 EZ - 2016/09/16 06:00 DA - 2012/12/01 00:01 DT - 2012/12/01 00:00 YR - 2012 ED - 20160917 RD - 20160916 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27628468 <61. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27100025 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Wang G AU - Jiang Z AU - Zhao J AU - Liu J AU - Zhang S AU - Zhao K AU - Feng X AU - Li J FA - Wang, Gang FA - Jiang, Zhiwei FA - Zhao, Jian FA - Liu, Jiang FA - Zhang, Shu FA - Zhao, Kun FA - Feng, Xiaobo FA - Li, Jieshou IN - Wang, Gang. Research Institute of General Surgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, China. IN - Jiang, Zhiwei. Research Institute of General Surgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, China. IN - Zhao, Jian. Research Institute of General Surgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, China. IN - Liu, Jiang. Research Institute of General Surgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, China. IN - Zhang, Shu. Research Institute of General Surgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, China. IN - Zhao, Kun. Research Institute of General Surgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, China. IN - Feng, Xiaobo. Research Institute of General Surgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, China. IN - Li, Jieshou. Research Institute of General Surgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, China. TI - Assessing the safety and efficacy of full robotic gastrectomy with intracorporeal robot-sewn anastomosis for gastric cancer: A randomized clinical trial. SO - Journal of Surgical Oncology. 113(4):397-404, 2016 Mar AS - J Surg Oncol. 113(4):397-404, 2016 Mar NJ - Journal of surgical oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - k79, 0222643 IO - J Surg Oncol SB - Index Medicus CP - United States MH - Anastomosis, Roux-en-Y/ae [Adverse Effects] MH - *Anastomosis, Roux-en-Y/mt [Methods] MH - Female MH - Gastrectomy/ae [Adverse Effects] MH - *Gastrectomy/mt [Methods] MH - Humans MH - Lymph Node Excision MH - Male MH - Middle Aged MH - Reconstructive Surgical Procedures/mt [Methods] MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures/mt [Methods] MH - *Stomach Neoplasms/su [Surgery] KW - D2 lymph node dissection; gastric cancer; robotic surgery; total gastrectomy AB - BACKGROUND: Robotic gastrectomy is increasingly used in gastric cancer patients. This study assessed the safety and efficacy of full robotic gastrectomy with intracorporeal robot-sewn anastomosis for gastric cancer. AB - METHODS: Three hundred and eleven patients were randomized into an open gastrectomy group or a robotic gastrectomy group, and digestive restorations were performed under direct vision and with intracorporeal robot-sewn anastomosis, respectively. Length of postoperative hospital stay, number of lymph node dissections, surgical duration, blood loss, and complication rate after surgery were recorded. AB - RESULTS: There were no significant differences in the number of lymph node dissections (30.9+/-10.4 vs. 29.3+/-9.7 days, P=0.281) or complication rates (10.3 vs. 9.3%, P=0.756) between the two groups. Surgical duration was significantly longer in the robotic gastrectomy group than in the open gastrectomy group (242.7+/-43.8 vs. 192.4+/-31.5min, P=0.002), whereas blood loss was less (94.2+/-51.5 vs. 152.8+/-76.9ml, P<0.001), length of postoperative hospital stay was shorter (5.6+/-1.9 vs. 6.7+/-1.9 days, P=0.021), and postoperative restoration of bowel function was earlier (2.6+/-1.1 vs. 3.1+/-1.2 days, P=0.028). AB - CONCLUSION: Full robotic gastrectomy with intracorporeal robot-sewn anastomosis for gastric cancer is safe and does not increase the complication risk during or after surgery. J. Surg. Oncol. 2016;113:397-404. © 2016 Wiley Periodicals, Inc. AB - Copyright © 2016 Wiley Periodicals, Inc. ES - 1096-9098 IL - 0022-4790 DO - https://dx.doi.org/10.1002/jso.24146 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 27100025 [pubmed] ID - 10.1002/jso.24146 [doi] PP - ppublish PH - 2015/10/06 [received] PH - 2015/12/13 [accepted] LG - English EP - 20160112 DP - 2016 Mar DC - 20160422 EZ - 2016/04/22 06:00 DA - 2016/08/30 06:00 DT - 2016/04/23 06:00 YR - 2016 ED - 20160829 RD - 20160422 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=27100025 <62. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25840895 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Fanfani F AU - Monterossi G AU - Fagotti A AU - Rossitto C AU - Gueli Alletti S AU - Costantini B AU - Gallotta V AU - Selvaggi L AU - Restaino S AU - Scambia G FA - Fanfani, Francesco FA - Monterossi, Giorgia FA - Fagotti, Anna FA - Rossitto, Cristiano FA - Gueli Alletti, Salvatore FA - Costantini, Barbara FA - Gallotta, Valerio FA - Selvaggi, Luigi FA - Restaino, Stefano FA - Scambia, Giovanni IN - Fanfani, Francesco. Division of Gynecologic Oncology, Department of Women and Child Health, Catholic University of the Sacred Heart, Rome, Italy. francesco.fanfani@rm.unicatt.it. IN - Monterossi, Giorgia. Division of Gynecologic Oncology, Department of Women and Child Health, Catholic University of the Sacred Heart, Rome, Italy. IN - Fagotti, Anna. Minimally Invasive Gynecology, St. Maria Hospital, University of Perugia, Terni, Italy. IN - Rossitto, Cristiano. Division of Gynecologic Oncology, Department of Women and Child Health, Catholic University of the Sacred Heart, Rome, Italy. IN - Gueli Alletti, Salvatore. Division of Gynecologic Oncology, Department of Women and Child Health, Catholic University of the Sacred Heart, Rome, Italy. IN - Costantini, Barbara. Division of Gynecologic Oncology, Department of Women and Child Health, Catholic University of the Sacred Heart, Rome, Italy. IN - Gallotta, Valerio. Division of Gynecologic Oncology, Department of Women and Child Health, Catholic University of the Sacred Heart, Rome, Italy. IN - Selvaggi, Luigi. Division of Gynecologic Oncology, Department of Women and Child Health, Catholic University of the Sacred Heart, Rome, Italy. IN - Restaino, Stefano. Division of Gynecologic Oncology, Department of Women and Child Health, Catholic University of the Sacred Heart, Rome, Italy. IN - Scambia, Giovanni. Division of Gynecologic Oncology, Department of Women and Child Health, Catholic University of the Sacred Heart, Rome, Italy. TI - The new robotic TELELAP ALF-X in gynecological surgery: single-center experience. SO - Surgical Endoscopy. 30(1):215-21, 2016 Jan AS - Surg Endosc. 30(1):215-21, 2016 Jan NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adult MH - Aged MH - Aged, 80 and over MH - Female MH - *Genital Diseases, Female/su [Surgery] MH - *Gynecologic Surgical Procedures MH - Humans MH - Italy MH - Middle Aged MH - Operative Time MH - Patient Outcome Assessment MH - Prospective Studies MH - *Robotic Surgical Procedures MH - Young Adult KW - Gynecology; Minimally invasive surgery; Robotic surgery; TELELAP ALF-X AB - BACKGROUND: To evaluate the safety and feasibility of the new robotic TELELAP ALF-X platform in a heterogeneous series of gynecological procedures. AB - METHODS: Between September 2013 and May 2014, 146 patients were enrolled in this Phase II study trial. Patients with presumed benign or borderline adnexal disease, and benign and early stage malignant uterine disease were prospectively included. AB - RESULTS: Median age was 52 years (range 19-79 years), and median BMI was 23.7 (range 17.3-34.0 kg/m(2)). Sixty-two patients (32.5%) underwent mono/bilateral salpingo-oophorectomy or cyst removal (Group A), four patients (2.7%) myomectomy (Group B), 46 patients (31.5%) total hysterectomy (Group C), and 34 (23.3%) endometrial cancer staging (Group D). Median docking time was 7 min (range 3-36). Median OT was 35 min (range 17-145) in the Group A, 40 min (range 10-50) in the Group B, 133 min (range 58-320) in the Group C, and 160 min (range 69-290) in the Group D. Reduction in OT over the study period for hysterectomy (p < 0.001) and adnexal surgery (p < 0.002) was observed. We registered two laparoscopic conversion (3.2%) in the Group A and two (4.3 %) in the Group C. In the Group D, we showed one (2.9%) laparoscopic and two (5.8%) laparotomic conversions. One patient (2.17%) in the Group C was readmitted in the early postoperative period for severe vaginal bleeding. AB - CONCLUSIONS: We report the first series of a novel robotic approach for the treatment of various gynecological conditions. When performed by experienced minimally invasive surgeons, TELELAP ALF-X is feasible and safe. Further studies are mandatory to define the benefits, advantages, and costs of this new robotic approach with respect to others minimally invasive approaches. ES - 1432-2218 IL - 0930-2794 DI - 10.1007/s00464-015-4187-9 DO - https://dx.doi.org/10.1007/s00464-015-4187-9 PT - Clinical Trial, Phase II PT - Journal Article ID - 25840895 [pubmed] ID - 10.1007/s00464-015-4187-9 [doi] ID - 10.1007/s00464-015-4187-9 [pii] PP - ppublish PH - 2014/11/24 [received] PH - 2015/03/24 [accepted] LG - English EP - 20150404 DP - 2016 Jan DC - 20160113 EZ - 2015/04/05 06:00 DA - 2016/08/26 06:00 DT - 2015/04/05 06:00 YR - 2016 ED - 20160825 RD - 20160113 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25840895 <63. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26530967 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lahaye L AU - Grasso M AU - Green J AU - Biddle CJ FA - Lahaye, Laura FA - Grasso, Mario FA - Green, Jeffrey FA - Biddle, C J IN - Lahaye, Laura. Department of Anesthesiology, Virginia Commonwealth University, Richmond, VA, USA. llahaye@mcvh-vcu.edu. IN - Grasso, Mario. Department of Anesthesiology, Virginia Commonwealth University, Richmond, VA, USA. IN - Green, Jeffrey. Department of Anesthesiology, Virginia Commonwealth University, Richmond, VA, USA. IN - Biddle, C J. Department of Anesthesiology, Virginia Commonwealth University, Richmond, VA, USA. TI - Cerebral tissue O2 saturation during prolonged robotic surgery in the steep Trendelenburg position: an observational case series in a diverse surgical population. SO - Journal of Robotic Surgery. 9(1):19-25, 2015 Mar AS - J. robot. surg.. 9(1):19-25, 2015 Mar NJ - Journal of robotic surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101300401 IO - J Robot Surg SB - Index Medicus CP - England MH - Adult MH - Aged MH - *Cerebrovascular Circulation/ph [Physiology] MH - Female MH - Humans MH - Male MH - Middle Aged MH - Oximetry MH - *Oxygen/bl [Blood] MH - Patient Positioning/ae [Adverse Effects] MH - *Patient Positioning/sn [Statistics & Numerical Data] MH - Patient Safety MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures/sn [Statistics & Numerical Data] MH - Spectroscopy, Near-Infrared MH - Young Adult KW - Cerebral tissue oxygenation; Phenylephrine; Robotic surgery; Steep trendelenburg position AB - Demands associated with the Trendelenburg position (TP) are well known yet there is little attention given to regional cerebral tissue O2 saturation (SctO2) in those undergoing robotic surgery in the TP with CO2 insufflation (C-INSF). This is the first study to report on SctO2 in a wide range of patients undergoing lengthy TP and robotic surgery. We measured SctO2 during robotic surgery in patients in the TP with C-INSF, as well as a control robotic thyroid surgery group who were supine with no C-INSF. We recorded relevant variables and periods of cerebral desaturation (CD). We studied 42 patients in 25degree-45degree of TP for >125 min. Management was at the providers' discretion. The INVOS() 5100C Cerebral Oximeter (Covidien, Boulder, CO) recorded SctO2. CD was defined as a >20 % decrease from baseline SctO2 or a value <55 % for >10 min. Patients were assessed for adverse outcome. The sample consisted of 13 males and 29 females aged 22-73, BMI 22-36 had general (N = 3), urological (N = 14) and gynecological (N = 25) surgery; two patients had CD lasting 150 and 190 min and two had episodic CD lasting 10-35 min. The four were female aged 22-60 in 38degree-45degree of TP. Eleven cases had multiple episodic CD for <15 min, 27 TP cases had no CD. Other observations included a consistent fall in SctO2 with phenylephrine; an increased SctO2 with ephedrine; and FiO2 and EtCO2 being generally strong, direct modifiers of SctO2. High MAP was inconsistently associated with high SctO2. BMI had no observed effect on SctO2. Pulse oximetry was >97 % in all cases. We observed no adverse cerebral events on follow-up. Additional clinical studies are warranted. RN - S88TT14065 (Oxygen) ES - 1863-2491 IL - 1863-2483 DI - 10.1007/s11701-014-0483-y DO - https://dx.doi.org/10.1007/s11701-014-0483-y PT - Journal Article PT - Observational Study PT - Research Support, Non-U.S. Gov't ID - 26530967 [pubmed] ID - 10.1007/s11701-014-0483-y [doi] ID - 10.1007/s11701-014-0483-y [pii] PP - ppublish PH - 2014/05/12 [received] PH - 2014/08/03 [accepted] LG - English EP - 20140821 DP - 2015 Mar DC - 20151104 EZ - 2015/11/05 06:00 DA - 2016/08/19 06:00 DT - 2015/11/05 06:00 YR - 2015 ED - 20160818 RD - 20151104 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26530967 <64. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26414847 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bhattu AS AU - Ganpule A AU - Sabnis RB AU - Murali V AU - Mishra S AU - Desai M FA - Bhattu, Amit Satish FA - Ganpule, Arvind FA - Sabnis, Ravindra B FA - Murali, Vinodh FA - Mishra, Shashikant FA - Desai, Mahesh IN - Bhattu, Amit Satish. Department of Urology, Muljibhai Patel Urological Hospital , Nadiad, India . IN - Ganpule, Arvind. Department of Urology, Muljibhai Patel Urological Hospital , Nadiad, India . IN - Sabnis, Ravindra B. Department of Urology, Muljibhai Patel Urological Hospital , Nadiad, India . IN - Murali, Vinodh. Department of Urology, Muljibhai Patel Urological Hospital , Nadiad, India . IN - Mishra, Shashikant. Department of Urology, Muljibhai Patel Urological Hospital , Nadiad, India . IN - Desai, Mahesh. Department of Urology, Muljibhai Patel Urological Hospital , Nadiad, India . TI - Robot-Assisted Laparoscopic Donor Nephrectomy vs Standard Laparoscopic Donor Nephrectomy: A Prospective Randomized Comparative Study. SO - Journal of Endourology. 29(12):1334-40, 2015 Dec AS - J Endourol. 29(12):1334-40, 2015 Dec NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - *Analgesics/tu [Therapeutic Use] MH - Female MH - Glomerular Filtration Rate MH - Humans MH - *Kidney Transplantation MH - *Laparoscopy/mt [Methods] MH - Length of Stay MH - *Living Donors MH - Male MH - Middle Aged MH - *Nephrectomy/mt [Methods] MH - Operative Time MH - *Pain, Postoperative/dt [Drug Therapy] MH - Postoperative Complications MH - Prospective Studies MH - *Robotic Surgical Procedures/mt [Methods] MH - Time Factors MH - *Tissue and Organ Harvesting/mt [Methods] MH - Treatment Outcome MH - Warm Ischemia AB - OBJECTIVE: The goal of this randomized controlled trial was to compare the outcomes of robot-assisted laparoscopic donor nephrectomy (RDN) with standard laparoscopic donor nephrectomy (LDN). AB - MATERIALS AND METHODS: Forty-five voluntary kidney donors (27 for right subgroup and 18 for left subgroup) who met inclusion and exclusion criteria were randomized into 2 groups, RDN and LDN in 1:2 ratio. Primary endpoints were visual analogue scale (VAS) pain scores, analgesic requirement, and hospital stay of donors. Secondary endpoints were donor's intraoperative and postoperative parameters, graft outcomes, and donor surgeon's difficulty scores. AB - RESULTS: All procedures were completed without any intraoperative complications. VAS pain scores at 6, 24, and 48 hours (p=0.00), analgesic requirement (p=0.00), and hospital stay (p=0.00) were less in RDN than in LDN. Longer graft arterial length could be preserved with robotic approach on right side (p=0.03) but not on left side (p=0.77). The RDN group required more number of ports (p=0.00), longer retrieval time (p=0.00), and warm ischemia time (WIT) (p=0.01). Total operative time (p=0.14), hemoglobin drop (p=0.97), postoperative donor complications (p=0.97), and the recipient estimated glomerular filtration rate at 9 months (p=0.64) were similar in both groups. Difficulty scores of console surgeon were less in most steps on right side but not on left side. Patient-side surgeon in RDN had higher difficulty scores for retrieval. AB - CONCLUSION: RDN is safe and is associated with better morbidity profile than LDN. Robotic approach provides technical ease and facilitates preservation of longer length of renal artery on right side. Left RDN is associated with longer WIT; however, this does not translate into poor graft outcome. RN - 0 (Analgesics) ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2015.0213 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 26414847 [pubmed] ID - 10.1089/end.2015.0213 [doi] PP - ppublish LG - English DP - 2015 Dec DC - 20151216 EZ - 2015/09/29 06:00 DA - 2016/08/11 06:00 DT - 2015/09/29 06:00 YR - 2015 ED - 20160810 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26414847 <65. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26131781 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Cestari A AU - Ferrari M AU - Ghezzi M AU - Sangalli M AU - Zanoni M AU - Fabbri F AU - Sozzi F AU - Lolli C AU - Dell'Acqua V AU - Rigatti P FA - Cestari, Andrea FA - Ferrari, Matteo FA - Ghezzi, Massimo FA - Sangalli, Mattia FA - Zanoni, Matteo FA - Fabbri, Fabio FA - Sozzi, Francesco FA - Lolli, Carolina FA - Dell'Acqua, Vincenzo FA - Rigatti, Patrizio IN - Cestari, Andrea. Department of Urology, Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano," Milan, Italy . IN - Ferrari, Matteo. Department of Urology, Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano," Milan, Italy . IN - Ghezzi, Massimo. Department of Urology, Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano," Milan, Italy . IN - Sangalli, Mattia. Department of Urology, Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano," Milan, Italy . IN - Zanoni, Matteo. Department of Urology, Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano," Milan, Italy . IN - Fabbri, Fabio. Department of Urology, Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano," Milan, Italy . IN - Sozzi, Francesco. Department of Urology, Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano," Milan, Italy . IN - Lolli, Carolina. Department of Urology, Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano," Milan, Italy . IN - Dell'Acqua, Vincenzo. Department of Urology, Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano," Milan, Italy . IN - Rigatti, Patrizio. Department of Urology, Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano," Milan, Italy . TI - Retropubic Intracorporeal Placement of a Suburethral Autologous Sling During Robot-Assisted Radical Prostatectomy to Improve Early Urinary Continence Recovery: Preliminary Data. SO - Journal of Endourology. 29(12):1379-85, 2015 Dec AS - J Endourol. 29(12):1379-85, 2015 Dec NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Aged MH - Humans MH - Male MH - Middle Aged MH - Operative Time MH - *Postoperative Complications/pc [Prevention & Control] MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - Recovery of Function MH - *Robotic Surgical Procedures/mt [Methods] MH - *Suburethral Slings MH - Surveys and Questionnaires MH - Transplantation, Autologous/mt [Methods] MH - Urethra MH - *Urinary Incontinence/pc [Prevention & Control] MH - Urodynamics MH - Urologic Surgical Procedures/mt [Methods] MH - *Vas Deferens/tr [Transplantation] AB - BACKGROUND AND PURPOSE: Urinary continence (UC) recovery remains bothersome for patients even after robot-assisted radical prostatectomy (RARP). We describe the first retropubic suburethral autologous sling created and placed during RARP. The surgical technique and preliminary data regarding its effectiveness in improving early UC recovery are presented. AB - PATIENTS AND METHODS: Between November 2013 and February 2014, 60 patients who underwent RARP at a single high-volume center were prospectively randomized into sling and nonsling groups. Early UC was assessed at 5 days (time of catheter removal), 10 days, and 30 days postoperatively by the daily number of pads used and the International Consultation on Incontinence Questionnaire-Urinary Incontinence-Short Form (ICIQ-UI-SF) score. Sling-related operative time and urethral erosion were also analyzed. Chi-square and independent sample t tests were used to investigate surgical and functional outcomes between groups. AB - RESULTS: Complete data were available for all patients. Mean+/-standard deviation (SD) numbers of pads used daily in nonsling and sling groups, respectively, were 1.9+/-1.2 versus 1.7+/-1.4 (P=0.5) at 5 days, 1.8+/-1.3 versus 1.3+/-1.3 (P=0.1) at 10 days, and 1.1+/-1.2 versus 0.4+/-0.8 (P=0.01) at 30 days. At 1 month, mean+/-SD ICIQ-UI-SF scores in nonsling and sling groups, respectively, were 4.8+/-4.6 versus 1.8+/-3.4 (P=0.01); sling patients were associated with pad-free status (76% vs 46%, P=0.03). The advantage in UC recovery was also observed in sling patients at 3, 6, and 12 months postoperatively. Surgical time did not differ between groups, and in sling patients, no cases of urethral erosion or uroflowmetry suggestive of urinary obstruction were found. Limitations included the small sample size and the lack of assessment of morphologic and urodynamic changes produced by the sling. AB - CONCLUSIONS: The suburethral autologous sling is technically feasible and may improve early UC recovery after RARP. These preliminary results should be confirmed in a larger sample of patients. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2015.0292 PT - Journal Article PT - Randomized Controlled Trial ID - 26131781 [pubmed] ID - 10.1089/end.2015.0292 [doi] PP - ppublish LG - English EP - 20150908 DP - 2015 Dec DC - 20151216 EZ - 2015/07/02 06:00 DA - 2016/08/11 06:00 DT - 2015/07/02 06:00 YR - 2015 ED - 20160810 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26131781 <66. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26945367 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lee YH AU - Kim YS AU - Chung MJ AU - Yu M AU - Jung SL AU - Yoo IeR AU - Lee YS AU - Kim MS AU - Sun DI AU - Kang JH FA - Lee, Yun Hee FA - Kim, Yeon Sil FA - Chung, Mi Joo FA - Yu, Mina FA - Jung, So Lyung FA - Yoo, Ie Ryung FA - Lee, Youn Soo FA - Kim, Min Sik FA - Sun, Dong Il FA - Kang, Jin Hyung IN - Lee, Yun Hee. From the Department of Radiation Oncology (LYH), Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju, Departments of Radiation Oncology (YSK), Radiology (SLJ), Nuclear medicine (IRY), Pathology (YSL), Otorhinolaryngology (MSK, DIS), Medical Oncology (JHK), Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea, Department of Radiation Oncology (MJC), Kyung Hee University Hospital at Gangdong, Seoul, South Korea, and Department of Radiation Oncology (MY), Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Republic of Korea. TI - Soft Tissue Necrosis in Head and Neck Cancer Patients After Transoral Robotic Surgery or Wide Excision With Primary Closure Followed by Radiation Therapy. SO - Medicine. 95(9):e2852, 2016 Mar AS - Medicine (Baltimore). 95(9):e2852, 2016 Mar NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782851 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - Head and Neck Neoplasms/co [Complications] MH - *Head and Neck Neoplasms/rt [Radiotherapy] MH - Head and Neck Neoplasms/su [Surgery] MH - Humans MH - Middle Aged MH - *Necrosis/et [Etiology] MH - *Postoperative Complications/et [Etiology] MH - *Radiation Injuries/pa [Pathology] MH - *Radiotherapy, Intensity-Modulated/ae [Adverse Effects] MH - Retrospective Studies MH - Risk Factors AB - Risk factors were evaluated for surgical bed soft tissue necrosis (STN) in head and neck cancer patients treated with postoperative radiation therapy (PORT) after transoral robotic surgery (TORS) or wide excision with primary closure. Sixty-seven patients were evaluated. STN was defined as ulceration and necrosis of the surgical bed or persistently unhealed high-grade acute mucositis with pain after PORT. The median RT dose of primary site was 63.6 Gy (range, 45-67.15 Gy) with 2 Gy/fx (range 1.8-2.2 Gy/fx). Total 41 patients (61.2%) were treated with concurrent chemoradiotherapy. The median follow-up period was 26 months. STN was diagnosed in 13 patients (19.4%). Most of the patients were treated with oral steroids, antibiotics, and analgesics and the lesions were eventually improved (median of 6 months after PORT). STN did not influence local control. A depth of invasion (DOI > 1.4 cm, odds ratio [OR] 14.04, p = 0.004) and maximum dose/fraction (CTVpmax/fx > 2.3 Gy, OR 6.344, p = 0.043) and grade 3 acute mucositis (OR 6.090, p = 0.054) were related to STN. The 12 (23.5%) of 51 oropharyngeal cancer patients presented STN, and the risk factors were DOI > 1.2 cm (OR 21.499, P = 0.005), CTVpmax/fx > 2.3 Gy (OR 12.972, P = 0.021) and grade 3 acute mucositis (OR 10.537, P = 0.052). Patients treated with TORS or WE with primary closure followed by PORT had a high risk of surgical bed STN. STN risk factors included DOI (>1.2-1.4 cm) and CTVpmax/fx (>2.3 Gy). Radiation therapy after TORS must be carefully designed to prevent STN. ES - 1536-5964 IL - 0025-7974 DI - 00005792-201603010-00021 DO - https://dx.doi.org/10.1097/MD.0000000000002852 PT - Journal Article PT - Observational Study ID - 26945367 [pubmed] ID - 10.1097/MD.0000000000002852 [doi] ID - 00005792-201603010-00021 [pii] ID - PMC4782851 [pmc] PP - ppublish LG - English DP - 2016 Mar DC - 20160306 EZ - 2016/03/06 06:00 DA - 2016/08/10 06:00 DT - 2016/03/06 06:00 YR - 2016 ED - 20160809 RD - 20160325 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26945367 <67. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26270117 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Fornalik H AU - Brooks H AU - Moore ES AU - Flanders NL AU - Callahan MJ AU - Sutton GP FA - Fornalik, Hubert FA - Brooks, Hannah FA - Moore, Elizabeth S FA - Flanders, Nicole L FA - Callahan, Michael J FA - Sutton, Gregory P IN - Fornalik, Hubert. Department of Obstetrics and Gynecology, St Vincent Hospital and Health Services, Indianapolis, IN. TI - Hand-Assisted Robotic Surgery for Staging of Ovarian Cancer and Uterine Cancers With High Risk of Peritoneal Spread: A Retrospective Cohort Study. SO - International Journal of Gynecological Cancer. 25(8):1488-93, 2015 Oct AS - Int J Gynecol Cancer. 25(8):1488-93, 2015 Oct NJ - International journal of gynecological cancer : official journal of the International Gynecological Cancer Society PI - Journal available in: Print PI - Citation processed from: Internet JC - dzp, 9111626 IO - Int. J. Gynecol. Cancer SB - Index Medicus CP - United States MH - Female MH - Follow-Up Studies MH - Humans MH - *Hysterectomy MH - *Laparoscopy MH - Length of Stay MH - Middle Aged MH - Neoplasm Recurrence, Local/mo [Mortality] MH - *Neoplasm Recurrence, Local/pa [Pathology] MH - Neoplasm Recurrence, Local/su [Surgery] MH - Neoplasm Staging MH - Ovarian Neoplasms/mo [Mortality] MH - *Ovarian Neoplasms/pa [Pathology] MH - Ovarian Neoplasms/su [Surgery] MH - Peritoneal Neoplasms/mo [Mortality] MH - *Peritoneal Neoplasms/sc [Secondary] MH - Peritoneal Neoplasms/su [Surgery] MH - Postoperative Complications MH - Prognosis MH - Retrospective Studies MH - Risk Factors MH - *Robotic Surgical Procedures MH - Survival Rate MH - Uterine Neoplasms/mo [Mortality] MH - *Uterine Neoplasms/pa [Pathology] MH - Uterine Neoplasms/su [Surgery] AB - OBJECTIVE: This study aimed to determine surgical outcomes related to hand-assisted robotic surgery (HARS) for staging of ovarian cancer and uterine cancers with high risk of peritoneal spread and compare them to laparotomy and standard robotic-assisted surgery. AB - METHODS: A retrospective cohort study of women undergoing staging for uterine and ovarian cancer between January 2011 and July 2013 at a major metropolitan teaching hospital was reviewed. Patients undergoing HARS were matched with patients undergoing staging laparotomy [exploratory laparotomy (XLAP)] for the same indications and with patients undergoing traditional robotic surgery (RS) for staging of endometrioid endometrial cancer. In HARS, a longer incision is used to allow palpation of the peritoneal surfaces, to exteriorize the small bowel, to examine the mesentery, and to perform omentectomy. AB - RESULTS: One hundred five patients were analyzed (15 HARS, 45 RS, 45 XLAP). Compared with XLAP, HARS was associated with decreased blood loss (200 vs 400 mL, P = 0.011) and shorter hospital stay (1 vs 4 days, P < 0.001). Patients who had undergone HARS had fewer major complications, but those results did not reach statistical significance (0% vs 27%, P = 0.063). Hand-assisted robotic surgery was associated with higher blood loss and length of stay as compared to robotic staging of endometrioid endometrial cancer (RS). Minor wound complications were also more common (27% vs 2%, P = 0.012). AB - CONCLUSIONS: Hand-assisted robotic surgery allows for thorough visual and tactile assessment of peritoneal surfaces. It represents a safe alternative to laparotomy for staging of ovarian and uterine cancers with high risk of peritoneal spread. Long-term follow-up study is needed to determine oncologic adequacy of HARS. ES - 1525-1438 IL - 1048-891X DO - https://dx.doi.org/10.1097/IGC.0000000000000508 PT - Journal Article ID - 26270117 [pubmed] ID - 10.1097/IGC.0000000000000508 [doi] PP - ppublish LG - English DP - 2015 Oct DC - 20150924 EZ - 2015/08/14 06:00 DA - 2016/08/05 06:00 DT - 2015/08/14 06:00 YR - 2015 ED - 20160804 RD - 20150924 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26270117 <68. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26506158 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Martin LA AU - Calixte R AU - Finamore PS FA - Martin, Lindsay Ann FA - Calixte, Rose FA - Finamore, Peter S IN - Martin, Lindsay Ann. From the *Division of Urogynecology, Department of Obstetrics and Gynecology, and +Department of Biostatistics, Winthrop University Hospital, Mineola, NY. TI - Reoperation After Robotic and Vaginal Mesh Reconstructive Surgery: A Retrospective Cohort Study. SO - Female Pelvic Medicine & Reconstructive Surgery. 21(6):315-8, 2015 Nov-Dec AS - Female pelvic med. reconstr. surg.. 21(6):315-8, 2015 Nov-Dec NJ - Female pelvic medicine & reconstructive surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 101528690 IO - Female Pelvic Med Reconstr Surg SB - Index Medicus CP - United States MH - Aged MH - Female MH - Gynecologic Surgical Procedures/ae [Adverse Effects] MH - *Gynecologic Surgical Procedures/mt [Methods] MH - Humans MH - Middle Aged MH - *Pelvic Organ Prolapse/su [Surgery] MH - Perioperative Period MH - Reoperation/sn [Statistics & Numerical Data] MH - Retrospective Studies MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures/mt [Methods] MH - Surgical Mesh MH - Treatment Outcome AB - OBJECTIVES: Our primary objective was to compare reoperations after robotic-assisted sacrocolpopexy and transvaginal mesh for apical prolapse repair. Our secondary aim was to record perioperative complications after robotic and vaginal surgeries. AB - METHODS: We reviewed medical records of women who underwent vaginal apical mesh support procedures or robotic sacrocolpopexy at Winthrop University Hospital between August 2009 and August 2013. We compared reoperations and perioperative complications between the 2 groups. AB - RESULTS: There were 245 eligible cases during the 4-year study period. One hundred eighty-one women underwent robotic-assisted sacrocolpopexy and 64 women underwent transvaginal mesh. Women who underwent robotic surgery were younger and had decreased blood loss. Patients were followed up for a median of 3 months after robotic surgery and 11.5 months after transvaginal mesh. We found no difference in overall rate of reoperation between robotic and transvaginal mesh repair for apical prolapse. Specifically, there was no difference in the rate of reoperation for mesh exposure. AB - CONCLUSIONS: Despite recent controversies, transvaginal mesh offers the benefit of an effective minimally invasive procedure with shorter operative times, and may not pose additional risk for reoperation when compared to robotic-assisted sacrocolpopexy. ES - 2154-4212 IL - 2151-8378 DI - 01436319-201511000-00004 DO - https://dx.doi.org/10.1097/SPV.0000000000000194 PT - Journal Article ID - 26506158 [pubmed] ID - 10.1097/SPV.0000000000000194 [doi] ID - 01436319-201511000-00004 [pii] PP - ppublish LG - English DP - 2015 Nov-Dec DC - 20151028 EZ - 2015/10/28 06:00 DA - 2016/08/02 06:00 DT - 2015/10/28 06:00 YR - 2015 ED - 20160801 RD - 20151028 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26506158 <69. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26482769 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Desiderio J AU - Jiang ZW AU - Nguyen NT AU - Zhang S AU - Reim D AU - Alimoglu O AU - Azagra JS AU - Yu PW AU - Coburn NG AU - Qi F AU - Jackson PG AU - Zang L AU - Brower ST AU - Kurokawa Y AU - Facy O AU - Tsujimoto H AU - Coratti A AU - Annecchiarico M AU - Bazzocchi F AU - Avanzolini A AU - Gagniere J AU - Pezet D AU - Cianchi F AU - Badii B AU - Novotny A AU - Eren T AU - Leblebici M AU - Goergen M AU - Zhang B AU - Zhao YL AU - Liu T AU - Al-Refaie W AU - Ma J AU - Takiguchi S AU - Lequeu JB AU - Trastulli S AU - Parisi A AI - Eren, Tunc; ORCID: http://orcid.org/0000-0001-7651-4321 FA - Desiderio, Jacopo FA - Jiang, Zhi-Wei FA - Nguyen, Ninh T FA - Zhang, Shu FA - Reim, Daniel FA - Alimoglu, Orhan FA - Azagra, Juan-Santiago FA - Yu, Pei-Wu FA - Coburn, Natalie G FA - Qi, Feng FA - Jackson, Patrick G FA - Zang, Lu FA - Brower, Steven T FA - Kurokawa, Yukinori FA - Facy, Olivier FA - Tsujimoto, Hironori FA - Coratti, Andrea FA - Annecchiarico, Mario FA - Bazzocchi, Francesca FA - Avanzolini, Andrea FA - Gagniere, Johan FA - Pezet, Denis FA - Cianchi, Fabio FA - Badii, Benedetta FA - Novotny, Alexander FA - Eren, Tunc FA - Leblebici, Metin FA - Goergen, Martine FA - Zhang, Ben FA - Zhao, Yong-Liang FA - Liu, Tong FA - Al-Refaie, Waddah FA - Ma, Junjun FA - Takiguchi, Shuji FA - Lequeu, Jean-Baptiste FA - Trastulli, Stefano FA - Parisi, Amilcare IN - Desiderio, Jacopo. Department of Digestive Surgery, St Mary's Hospital, University of Perugia, Terni, Italy. IN - Jiang, Zhi-Wei. Department of General Surgery, Jinling Hospital, Medical School, Nanjing University, Nanjing, China. IN - Nguyen, Ninh T. Department of Surgery, Division of Gastrointestinal Surgery, University of California, Irvine Medical Center, Orange, California, USA. IN - Zhang, Shu. Department of General Surgery, Jinling Hospital, Medical School, Nanjing University, Nanjing, China. IN - Reim, Daniel. Chirurgische Klinik und Poliklinik, Klinikum Rechts der Isar der Technischen Universitat Munchen, Munchen, Germany. IN - Alimoglu, Orhan. Department of General Surgery, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey. IN - Azagra, Juan-Santiago. Unite des Maladies de l'Appareil Digestif et Endocrine (UMADE), Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg. IN - Yu, Pei-Wu. Department of General Surgery, Third Military Medical University Southwest Hospital, Chongqing, China. IN - Coburn, Natalie G. Division of General Surgery, Sunnybrook Health Sciences Centre, Toronto, Canada. IN - Qi, Feng. Department of Gastrointestinal Surgery, Tianjin Medical University General Hospital, Tianjin, China. IN - Jackson, Patrick G. Division of General Surgery, Medstar Georgetown University Hospital, Washington DC, USA. IN - Zang, Lu. Department of Surgery, Ruijin Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China. IN - Brower, Steven T. Department of Surgical Oncology and HPB Surgery, Englewood Hospital and Medical Center, Englewood, New Jersey, USA. IN - Kurokawa, Yukinori. Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan. IN - Facy, Olivier. Service de chirurgie digestive et cancerologique CHU Bocage. Dijon, France. IN - Tsujimoto, Hironori. Department of Surgery, National Defense Medical College, Tokorozawa, Japan. IN - Coratti, Andrea. Division of Oncological and Robotic Surgery, Department of Oncology, Careggi University Hospital, Florence, Italy. IN - Annecchiarico, Mario. Division of Oncological and Robotic Surgery, Department of Oncology, Careggi University Hospital, Florence, Italy. IN - Bazzocchi, Francesca. Department of General Surgery, Division of General, Gastroenterologic and Minimally Invasive Surgery, GB Morgagni Hospital, Forli, Italy. IN - Avanzolini, Andrea. Department of General Surgery, Division of General, Gastroenterologic and Minimally Invasive Surgery, GB Morgagni Hospital, Forli, Italy. IN - Gagniere, Johan. Digestive and Hepatobiliary Surgery Department, University of Auvergne, University Hospital Estaing, Clermont-Ferrand, France. IN - Pezet, Denis. Digestive and Hepatobiliary Surgery Department, University of Auvergne, University Hospital Estaing, Clermont-Ferrand, France. IN - Cianchi, Fabio. Department of Surgery and Translational Medicine, Center of Oncological Minimally Invasive Surgery (COMIS), University of Florence, Florence, Italy. IN - Badii, Benedetta. Department of Surgery and Translational Medicine, Center of Oncological Minimally Invasive Surgery (COMIS), University of Florence, Florence, Italy. IN - Novotny, Alexander. Chirurgische Klinik und Poliklinik, Klinikum Rechts der Isar der Technischen Universitat Munchen, Munchen, Germany. IN - Eren, Tunc. Department of General Surgery, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey. IN - Leblebici, Metin. Department of General Surgery, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey. IN - Goergen, Martine. Unite des Maladies de l'Appareil Digestif et Endocrine (UMADE), Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg. IN - Zhang, Ben. Department of General Surgery, Third Military Medical University Southwest Hospital, Chongqing, China. IN - Zhao, Yong-Liang. Department of General Surgery, Third Military Medical University Southwest Hospital, Chongqing, China. IN - Liu, Tong. Department of Gastrointestinal Surgery, Tianjin Medical University General Hospital, Tianjin, China. IN - Al-Refaie, Waddah. Division of General Surgery, Medstar Georgetown University Hospital, Washington DC, USA. IN - Ma, Junjun. Department of Surgery, Ruijin Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China. IN - Takiguchi, Shuji. Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan. IN - Lequeu, Jean-Baptiste. Service de chirurgie digestive et cancerologique CHU Bocage. Dijon, France. IN - Trastulli, Stefano. Department of Digestive Surgery, St Mary's Hospital, University of Perugia, Terni, Italy. IN - Parisi, Amilcare. Department of Digestive Surgery, St Mary's Hospital, University of Perugia, Terni, Italy. TI - Robotic, laparoscopic and open surgery for gastric cancer compared on surgical, clinical and oncological outcomes: a multi-institutional chart review. A study protocol of the International study group on Minimally Invasive surgery for GASTRIc Cancer-IMIGASTRIC. SO - BMJ Open. 5(10):e008198, 2015 Oct 19 AS - BMJ Open. 5(10):e008198, 2015 Oct 19 NJ - BMJ open PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101552874 IO - BMJ Open PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611863 SB - Index Medicus CP - England MH - Databases, Factual MH - Female MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - *Minimally Invasive Surgical Procedures/mt [Methods] MH - Reproducibility of Results MH - *Research Design MH - Retrospective Studies MH - *Robotics/is [Instrumentation] MH - *Stomach Neoplasms/su [Surgery] MH - Treatment Outcome KW - SURGERY AB - INTRODUCTION: Gastric cancer represents a great challenge for healthcare providers and requires a multidisciplinary treatment approach in which surgery plays a major role. Minimally invasive surgery has been progressively developed, first with the advent of laparoscopy and recently with the spread of robotic surgery, but a number of issues are currently being debated, including the limitations in performing an effective extended lymph node dissection, the real advantages of robotic systems, the role of laparoscopy for Advanced Gastric Cancer, the reproducibility of a total intracorporeal technique and the oncological results achievable during long-term follow-up. AB - METHODS AND ANALYSIS: A multi-institutional international database will be established to evaluate the role of robotic, laparoscopic and open approaches in gastric cancer, comprising of information regarding surgical, clinical and oncological features. A chart review will be conducted to enter data of participants with gastric cancer, previously treated at the participating institutions. The database is the first of its kind, through an international electronic submission system and a HIPPA protected real time data repository from high volume gastric cancer centres. AB - ETHICS AND DISSEMINATION: This study is conducted in compliance with ethical principles originating from the Helsinki Declaration, within the guidelines of Good Clinical Practice and relevant laws/regulations. A multicentre study with a large number of patients will permit further investigation of the safety and efficacy as well as the long-term outcomes of robotic, laparoscopic and open approaches for the management of gastric cancer. AB - TRIAL REGISTRATION NUMBER: NCT02325453; Pre-results. AB - Copyright Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. ES - 2044-6055 IL - 2044-6055 DI - bmjopen-2015-008198 DO - https://dx.doi.org/10.1136/bmjopen-2015-008198 PT - Journal Article PT - Multicenter Study PT - Observational Study PT - Research Support, Non-U.S. Gov't ID - 26482769 [pubmed] ID - bmjopen-2015-008198 [pii] ID - 10.1136/bmjopen-2015-008198 [doi] ID - PMC4611863 [pmc] PP - epublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT02325453 SA - ClinicalTrials.gov/NCT02325453 SL - https://clinicaltrials.gov/search/term=NCT02325453 SL - https://clinicaltrials.gov/search/term=NCT02325453 LG - English EP - 20151019 DP - 2015 Oct 19 DC - 20151020 EZ - 2015/10/21 06:00 DA - 2016/08/02 06:00 DT - 2015/10/21 06:00 YR - 2015 ED - 20160801 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26482769 <70. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26482769 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Desiderio J AU - Jiang ZW AU - Nguyen NT AU - Zhang S AU - Reim D AU - Alimoglu O AU - Azagra JS AU - Yu PW AU - Coburn NG AU - Qi F AU - Jackson PG AU - Zang L AU - Brower ST AU - Kurokawa Y AU - Facy O AU - Tsujimoto H AU - Coratti A AU - Annecchiarico M AU - Bazzocchi F AU - Avanzolini A AU - Gagniere J AU - Pezet D AU - Cianchi F AU - Badii B AU - Novotny A AU - Eren T AU - Leblebici M AU - Goergen M AU - Zhang B AU - Zhao YL AU - Liu T AU - Al-Refaie W AU - Ma J AU - Takiguchi S AU - Lequeu JB AU - Trastulli S AU - Parisi A AI - Eren, Tunc; ORCID: http://orcid.org/0000-0001-7651-4321 FA - Desiderio, Jacopo FA - Jiang, Zhi-Wei FA - Nguyen, Ninh T FA - Zhang, Shu FA - Reim, Daniel FA - Alimoglu, Orhan FA - Azagra, Juan-Santiago FA - Yu, Pei-Wu FA - Coburn, Natalie G FA - Qi, Feng FA - Jackson, Patrick G FA - Zang, Lu FA - Brower, Steven T FA - Kurokawa, Yukinori FA - Facy, Olivier FA - Tsujimoto, Hironori FA - Coratti, Andrea FA - Annecchiarico, Mario FA - Bazzocchi, Francesca FA - Avanzolini, Andrea FA - Gagniere, Johan FA - Pezet, Denis FA - Cianchi, Fabio FA - Badii, Benedetta FA - Novotny, Alexander FA - Eren, Tunc FA - Leblebici, Metin FA - Goergen, Martine FA - Zhang, Ben FA - Zhao, Yong-Liang FA - Liu, Tong FA - Al-Refaie, Waddah FA - Ma, Junjun FA - Takiguchi, Shuji FA - Lequeu, Jean-Baptiste FA - Trastulli, Stefano FA - Parisi, Amilcare IN - Desiderio, Jacopo. Department of Digestive Surgery, St Mary's Hospital, University of Perugia, Terni, Italy. IN - Jiang, Zhi-Wei. Department of General Surgery, Jinling Hospital, Medical School, Nanjing University, Nanjing, China. IN - Nguyen, Ninh T. Department of Surgery, Division of Gastrointestinal Surgery, University of California, Irvine Medical Center, Orange, California, USA. IN - Zhang, Shu. Department of General Surgery, Jinling Hospital, Medical School, Nanjing University, Nanjing, China. IN - Reim, Daniel. Chirurgische Klinik und Poliklinik, Klinikum Rechts der Isar der Technischen Universitat Munchen, Munchen, Germany. IN - Alimoglu, Orhan. Department of General Surgery, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey. IN - Azagra, Juan-Santiago. Unite des Maladies de l'Appareil Digestif et Endocrine (UMADE), Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg. IN - Yu, Pei-Wu. Department of General Surgery, Third Military Medical University Southwest Hospital, Chongqing, China. IN - Coburn, Natalie G. Division of General Surgery, Sunnybrook Health Sciences Centre, Toronto, Canada. IN - Qi, Feng. Department of Gastrointestinal Surgery, Tianjin Medical University General Hospital, Tianjin, China. IN - Jackson, Patrick G. Division of General Surgery, Medstar Georgetown University Hospital, Washington DC, USA. IN - Zang, Lu. Department of Surgery, Ruijin Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China. IN - Brower, Steven T. Department of Surgical Oncology and HPB Surgery, Englewood Hospital and Medical Center, Englewood, New Jersey, USA. IN - Kurokawa, Yukinori. Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan. IN - Facy, Olivier. Service de chirurgie digestive et cancerologique CHU Bocage. Dijon, France. IN - Tsujimoto, Hironori. Department of Surgery, National Defense Medical College, Tokorozawa, Japan. IN - Coratti, Andrea. Division of Oncological and Robotic Surgery, Department of Oncology, Careggi University Hospital, Florence, Italy. IN - Annecchiarico, Mario. Division of Oncological and Robotic Surgery, Department of Oncology, Careggi University Hospital, Florence, Italy. IN - Bazzocchi, Francesca. Department of General Surgery, Division of General, Gastroenterologic and Minimally Invasive Surgery, GB Morgagni Hospital, Forli, Italy. IN - Avanzolini, Andrea. Department of General Surgery, Division of General, Gastroenterologic and Minimally Invasive Surgery, GB Morgagni Hospital, Forli, Italy. IN - Gagniere, Johan. Digestive and Hepatobiliary Surgery Department, University of Auvergne, University Hospital Estaing, Clermont-Ferrand, France. IN - Pezet, Denis. Digestive and Hepatobiliary Surgery Department, University of Auvergne, University Hospital Estaing, Clermont-Ferrand, France. IN - Cianchi, Fabio. Department of Surgery and Translational Medicine, Center of Oncological Minimally Invasive Surgery (COMIS), University of Florence, Florence, Italy. IN - Badii, Benedetta. Department of Surgery and Translational Medicine, Center of Oncological Minimally Invasive Surgery (COMIS), University of Florence, Florence, Italy. IN - Novotny, Alexander. Chirurgische Klinik und Poliklinik, Klinikum Rechts der Isar der Technischen Universitat Munchen, Munchen, Germany. IN - Eren, Tunc. Department of General Surgery, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey. IN - Leblebici, Metin. Department of General Surgery, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey. IN - Goergen, Martine. Unite des Maladies de l'Appareil Digestif et Endocrine (UMADE), Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg. IN - Zhang, Ben. Department of General Surgery, Third Military Medical University Southwest Hospital, Chongqing, China. IN - Zhao, Yong-Liang. Department of General Surgery, Third Military Medical University Southwest Hospital, Chongqing, China. IN - Liu, Tong. Department of Gastrointestinal Surgery, Tianjin Medical University General Hospital, Tianjin, China. IN - Al-Refaie, Waddah. Division of General Surgery, Medstar Georgetown University Hospital, Washington DC, USA. IN - Ma, Junjun. Department of Surgery, Ruijin Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China. IN - Takiguchi, Shuji. Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan. IN - Lequeu, Jean-Baptiste. Service de chirurgie digestive et cancerologique CHU Bocage. Dijon, France. IN - Trastulli, Stefano. Department of Digestive Surgery, St Mary's Hospital, University of Perugia, Terni, Italy. IN - Parisi, Amilcare. Department of Digestive Surgery, St Mary's Hospital, University of Perugia, Terni, Italy. TI - Robotic, laparoscopic and open surgery for gastric cancer compared on surgical, clinical and oncological outcomes: a multi-institutional chart review. A study protocol of the International study group on Minimally Invasive surgery for GASTRIc Cancer-IMIGASTRIC. SO - BMJ Open. 5(10):e008198, 2015 Oct 19 AS - BMJ Open. 5(10):e008198, 2015 Oct 19 NJ - BMJ open PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101552874 IO - BMJ Open PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611863 SB - Index Medicus CP - England MH - Databases, Factual MH - Female MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - *Minimally Invasive Surgical Procedures/mt [Methods] MH - Reproducibility of Results MH - *Research Design MH - Retrospective Studies MH - *Robotics/is [Instrumentation] MH - *Stomach Neoplasms/su [Surgery] MH - Treatment Outcome KW - SURGERY AB - INTRODUCTION: Gastric cancer represents a great challenge for healthcare providers and requires a multidisciplinary treatment approach in which surgery plays a major role. Minimally invasive surgery has been progressively developed, first with the advent of laparoscopy and recently with the spread of robotic surgery, but a number of issues are currently being debated, including the limitations in performing an effective extended lymph node dissection, the real advantages of robotic systems, the role of laparoscopy for Advanced Gastric Cancer, the reproducibility of a total intracorporeal technique and the oncological results achievable during long-term follow-up. AB - METHODS AND ANALYSIS: A multi-institutional international database will be established to evaluate the role of robotic, laparoscopic and open approaches in gastric cancer, comprising of information regarding surgical, clinical and oncological features. A chart review will be conducted to enter data of participants with gastric cancer, previously treated at the participating institutions. The database is the first of its kind, through an international electronic submission system and a HIPPA protected real time data repository from high volume gastric cancer centres. AB - ETHICS AND DISSEMINATION: This study is conducted in compliance with ethical principles originating from the Helsinki Declaration, within the guidelines of Good Clinical Practice and relevant laws/regulations. A multicentre study with a large number of patients will permit further investigation of the safety and efficacy as well as the long-term outcomes of robotic, laparoscopic and open approaches for the management of gastric cancer. AB - TRIAL REGISTRATION NUMBER: NCT02325453; Pre-results. AB - Copyright Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. ES - 2044-6055 IL - 2044-6055 DI - bmjopen-2015-008198 DO - https://dx.doi.org/10.1136/bmjopen-2015-008198 PT - Journal Article PT - Multicenter Study PT - Observational Study PT - Research Support, Non-U.S. Gov't ID - 26482769 [pubmed] ID - bmjopen-2015-008198 [pii] ID - 10.1136/bmjopen-2015-008198 [doi] ID - PMC4611863 [pmc] PP - epublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT02325453 SL - https://clinicaltrials.gov/search/term=NCT02325453 LG - English EP - 20151019 DP - 2015 Oct 19 DC - 20151020 EZ - 2015/10/21 06:00 DA - 2016/08/02 06:00 DT - 2015/10/21 06:00 YR - 2015 ED - 20160801 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=26482769 <71. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26673533 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Yang JY AU - Son YG AU - Kim TH AU - Park JH AU - Huh YJ AU - Suh YS AU - Kong SH AU - Lee HJ AU - Kim S AU - Yang HK FA - Yang, Jun-Young FA - Son, Young-Gil FA - Kim, Tae Han FA - Park, Ji-Ho FA - Huh, Yeon-Ju FA - Suh, Yun-Suhk FA - Kong, Seong-Ho FA - Lee, Hyuk-Joon FA - Kim, Sungwan FA - Yang, Han-Kwang IN - Yang, Jun-Young. 1 Department of Surgery, Seoul National University College of Medicine , Seoul, Korea. IN - Son, Young-Gil. 1 Department of Surgery, Seoul National University College of Medicine , Seoul, Korea. IN - Kim, Tae Han. 1 Department of Surgery, Seoul National University College of Medicine , Seoul, Korea. IN - Park, Ji-Ho. 1 Department of Surgery, Seoul National University College of Medicine , Seoul, Korea. IN - Huh, Yeon-Ju. 1 Department of Surgery, Seoul National University College of Medicine , Seoul, Korea. IN - Suh, Yun-Suhk. 1 Department of Surgery, Seoul National University College of Medicine , Seoul, Korea. IN - Kong, Seong-Ho. 1 Department of Surgery, Seoul National University College of Medicine , Seoul, Korea. IN - Lee, Hyuk-Joon. 1 Department of Surgery, Seoul National University College of Medicine , Seoul, Korea. IN - Lee, Hyuk-Joon. 2 Cancer Research Institute, Seoul National University College of Medicine , Seoul, Korea. IN - Kim, Sungwan. 3 Department of Biomedical Engineering, Seoul National University College of Medicine , Seoul, Korea. IN - Yang, Han-Kwang. 1 Department of Surgery, Seoul National University College of Medicine , Seoul, Korea. IN - Yang, Han-Kwang. 2 Cancer Research Institute, Seoul National University College of Medicine , Seoul, Korea. TI - Manual Ambidexterity Predicts Robotic Surgical Proficiency. SO - Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A. 25(12):1009-18, 2015 Dec AS - J Laparoendosc Adv Surg Tech A. 25(12):1009-18, 2015 Dec NJ - Journal of laparoendoscopic & advanced surgical techniques. Part A PI - Journal available in: Print PI - Citation processed from: Internet JC - 9706293, c0d IO - J Laparoendosc Adv Surg Tech A SB - Index Medicus CP - United States MH - Adult MH - *Clinical Competence MH - Female MH - *Functional Laterality MH - Humans MH - Laparoscopy MH - Male MH - *Robotic Surgical Procedures MH - Simulation Training MH - *Suture Techniques AB - BACKGROUND: The manual dexterity of a surgeon is known to be related with surgical proficiency. Recently, as an objective measurement of surgical skills, inanimate methods using several types of simulators have been introduced. Using these simulators, we aimed to investigate the impact of manual dexterity on laparoscopic and robotic surgical proficiency. AB - MATERIALS AND METHODS: Fellow surgeons, surgical residents, and medical students (n=32) participated in this study. For the measurement of dexterity, the sums and differences of the right and left hand performance times for the Grooved Pegboard Test were used as an index of dexterity speed and ambidexterity, respectively. The performance times during three sessions of laparoscopic suturing using a D-box trainer and the performance scores during three sessions using two robotic suturing programs with different degrees of difficulty provided by the da Vinci Skills SimulatorTM (Intuitive Surgical Inc., Sunnyvale, CA) were analyzed according to the measured manual dexterity. AB - RESULTS: Manual dexterity was not a significant factor for performance time during laparoscopic suturing, which was more influenced by participants' surgical experiences. In robotic suturing, the performance score was impacted significantly by manual dexterity in terms of ambidexterity rather than dexterity speed. For an easy robotic suturing task, the gap of proficiency between the lower and higher ambidexterity groups was decreased successively with each of the three sessions. However, that gap in cases with a difficult task was maintained consistently throughout all three sessions. AB - CONCLUSIONS: The degree of ambidexterity was an initial predictor for proficiency with simulated robotic suture. However, this relation could be lessened through a few sessions of training, although for a more difficult task further repetitions would be needed. ES - 1557-9034 IL - 1092-6429 DO - https://dx.doi.org/10.1089/lap.2015.0288 PT - Clinical Trial PT - Journal Article ID - 26673533 [pubmed] ID - 10.1089/lap.2015.0288 [doi] PP - ppublish LG - English DP - 2015 Dec DC - 20151217 EZ - 2015/12/18 06:00 DA - 2016/07/28 06:00 DT - 2015/12/18 06:00 YR - 2015 ED - 20160727 RD - 20151217 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26673533 <72. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26329741 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Gezginci E AU - Ozkaptan O AU - Yalcin S AU - Akin Y AU - Rassweiler J AU - Gozen AS FA - Gezginci, Elif FA - Ozkaptan, Orkunt FA - Yalcin, Serdar FA - Akin, Yigit FA - Rassweiler, Jens FA - Gozen, Ali Serdar IN - Gezginci, Elif. School of Nursing, Gulhane Military Medical Academy, Ankara, Turkey. IN - Ozkaptan, Orkunt. Department of Urology, Avrasya Hospital, Istanbul, Turkey. IN - Yalcin, Serdar. Department of Urology, Gulhane Military Medical Academy, Ankara, Turkey. IN - Akin, Yigit. Department of Urology, SLK-Kliniken, University of Heidelberg, Am Gesundbrunnen 20-26, 74078, Heilbronn, Germany. IN - Rassweiler, Jens. Department of Urology, SLK-Kliniken, University of Heidelberg, Am Gesundbrunnen 20-26, 74078, Heilbronn, Germany. IN - Gozen, Ali Serdar. Department of Urology, SLK-Kliniken, University of Heidelberg, Am Gesundbrunnen 20-26, 74078, Heilbronn, Germany. asgozen@gmail.com. TI - Postoperative pain and neuromuscular complications associated with patient positioning after robotic assisted laparoscopic radical prostatectomy: a retrospective non-placebo and non-randomized study. SO - International Urology & Nephrology. 47(10):1635-41, 2015 Oct AS - Int Urol Nephrol. 47(10):1635-41, 2015 Oct NJ - International urology and nephrology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - guq, 0262521 IO - Int Urol Nephrol SB - Index Medicus CP - Netherlands MH - Aged MH - Body Mass Index MH - Comorbidity MH - Head-Down Tilt/ae [Adverse Effects] MH - Health Status MH - Humans MH - Hypesthesia/et [Etiology] MH - Male MH - Middle Aged MH - Muscle Weakness/et [Etiology] MH - Pain Measurement MH - *Pain, Postoperative/et [Etiology] MH - Paresthesia/et [Etiology] MH - *Patient Positioning/ae [Adverse Effects] MH - *Prostatectomy/ae [Adverse Effects] MH - Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - Prostheses and Implants MH - Retrospective Studies MH - *Robotic Surgical Procedures/ae [Adverse Effects] KW - Complications; Ergonomics; Pain; Prostate cancer; Robotics AB - PURPOSE: To evaluate postoperative pain and neuromuscular complications associated with positioning after robotic assisted laparoscopic radical prostatectomy (RALP). AB - METHODS: Between September 2010 and June 2014, 534 patients who underwent RALP were evaluated. Patients were positioned in operating theater by operating room staff, and two independent urologists noted postoperative follow-up. Patient's demographic data, postoperative complications associated with positioning, pain score according to visual analogue scale, and hospital stay were recorded. Statistical analyses were performed and p < 0.05 was considered significant. AB - RESULTS: Postoperative pain and neuromuscular complications were observed in 54 (10.1 %) and 27 (5 %) patients, respectively. We found ASA, BMI, and comorbidities were significantly associated with postoperative pain levels in univariate analyses (p = 0.01, p = 0.013, and p = 0.01, respectively). Additionally, ASA, previous operations, and comorbidities were significantly associated with postoperative neuromuscular complications (p = 0.04, p = 0.01, and p = 0.02, respectively). According to statistical analyses, BMI < 30 and presence of an implant were significantly associated with postoperative pain in multivariate logistic regression analyses (p = 0.010 and p = 0.033, respectively). Additionally, having comorbidities was significantly associated with postoperative neuromuscular complications in multivariate analyses (p = 0.04). AB - CONCLUSIONS: Patients with previous operations, comorbidities, and high ASA score are at risk of neuromuscular complications during RALP. Lower BMI and having an implant also lead to higher postoperative pain. Operating room staff and anaesthesia team should be very careful with patients undergoing RALP in steep Trendelenburg and low-lithotomy position. ES - 1573-2584 IL - 0301-1623 DI - 10.1007/s11255-015-1088-8 DO - https://dx.doi.org/10.1007/s11255-015-1088-8 PT - Journal Article ID - 26329741 [pubmed] ID - 10.1007/s11255-015-1088-8 [doi] ID - 10.1007/s11255-015-1088-8 [pii] PP - ppublish PH - 2015/07/22 [received] PH - 2015/08/14 [accepted] LG - English EP - 20150902 DP - 2015 Oct DC - 20151012 EZ - 2015/09/03 06:00 DA - 2016/07/22 06:00 DT - 2015/09/04 06:00 YR - 2015 ED - 20160721 RD - 20151012 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26329741 <73. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26321172 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lopez S AU - Mulla ZD AU - Hernandez L AU - Garza DM AU - Payne TN AU - Farnam RW FA - Lopez, Sandra FA - Mulla, Zuber D FA - Hernandez, Loretta FA - Garza, Devin M FA - Payne, Thomas N FA - Farnam, Richard W IN - Lopez, Sandra. Department of Obstetrics and Gynecology, Texas Tech University Health Sciences Center, El Paso, TX. Electronic address: sandra.lopez@ttuhsc.edu. IN - Mulla, Zuber D. Department of Obstetrics and Gynecology, Texas Tech University Health Sciences Center, El Paso, TX. IN - Hernandez, Loretta. Department of Obstetrics and Gynecology, Texas Tech University Health Sciences Center, El Paso, TX. IN - Garza, Devin M. Texas Institute for Robotic Surgery, St. David's North Austin Medical Center, Austin, TX. IN - Payne, Thomas N. Texas Institute for Robotic Surgery, St. David's North Austin Medical Center, Austin, TX. IN - Farnam, Richard W. Department of Obstetrics and Gynecology, Texas Tech University Health Sciences Center, El Paso, TX. TI - A Comparison of Outcomes Between Robotic-Assisted, Single-Site Laparoscopy Versus Laparoendoscopic Single Site for Benign Hysterectomy. SO - Journal of Minimally Invasive Gynecology. 23(1):84-8, 2016 Jan AS - J Minim Invasive Gynecol. 23(1):84-8, 2016 Jan NJ - Journal of minimally invasive gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101235322 IO - J Minim Invasive Gynecol SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Endoscopy/mt [Methods] MH - *Endoscopy MH - Female MH - Humans MH - Hysterectomy/mt [Methods] MH - *Hysterectomy MH - Laparoscopy/mt [Methods] MH - *Laparoscopy MH - *Length of Stay/sn [Statistics & Numerical Data] MH - Middle Aged MH - Odds Ratio MH - Operative Time MH - Outcome Assessment (Health Care) MH - Retrospective Studies KW - Hysterectomy; Laparoendoscopic single site (LESS); Robotic-assisted single site AB - STUDY OBJECTIVE: To compare the perioperative outcomes, including estimated blood loss, conversion to open laparotomy, length of stay, and total operative time of hysterectomies using robotic-assisted, single-site laparoscopy with laparoendoscopic single site (LESS) for benign indications. AB - DESIGN: A retrospective cohort study (Canadian Task Force classification Level II-2. AB - SETTING: Multicenter (private hospitals). AB - PATIENTS: Gynecologic patients who underwent a hysterectomy for benign indications via robotic-assisted, single-site laparoscopy (n = 50) versus LESS (n = 50). AB - INTERVENTIONS: Observational study. AB - MEASUREMENTS AND MAIN RESULTS: Continuous outcomes were analyzed using multiple linear regression, whereas the dichotomous outcome of conversion was analyzed using a multiple log-binomial regression model. Linear and log-binomial regression coefficients were adjusted for the ages of the patients and other clinical factors. A total of 100 consecutive patient records were available for analysis: 50 for robotic-assisted, single-site laparoscopy and 50 for LESS. Univariate analyses revealed that both groups were similar in mean age (robotic, 46.0 years; LESS, 45.4 years; p = .75), but not mean body mass index (robotic, 25.9 kg/m(2); LESS, 28.8 kg/m(2); p = .02). There was no difference in the unadjusted (crude) risk of conversion to a multiport procedure between the robotic and laparoscopic groups (p = .37). There were only 2 major complications (cystotomy and vaginal dehiscence) in the LESS arm and 1 vaginal dehiscence in the robotic-assisted, single-site arm. After adjusting for 7 potential confounders, no relationship was detected between the type of approach (robotic vs laparoscopic) and the outcome of a major complication (exact odds ratio, 0.55; exact p = 1.0). A multivariate linear regression analysis that compared the 2 groups (robotic-assisted single site vs LESS) revealed no differences in estimated blood loss. On average, the robotic-assisted, single-site group had a length of stay that was 8.12 hours shorter than the LESS group (p = .003) after adjusting for patient characteristics. Total operative time was an average of 24.9 min longer in the robotic-assisted, single-site group (p = .002) after adjustment. A plot of total operative time in minutes by chronological case number and procedural approach was analyzed to estimate a learning curve. This plot showed a steeper learning curve with the robotic-assisted, single-site approach. AB - CONCLUSIONS: This preliminary observational study found that the robotic-assisted, single-site group had a statistically significant decrease in length of hospital stay, but also experienced an increase in total operative time. There were no conversions to open laparotomies. AB - Copyright Published by Elsevier Inc. ES - 1553-4669 IL - 1553-4650 DI - S1553-4650(15)01491-0 DO - https://dx.doi.org/10.1016/j.jmig.2015.08.883 PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Observational Study ID - 26321172 [pubmed] ID - S1553-4650(15)01491-0 [pii] ID - 10.1016/j.jmig.2015.08.883 [doi] PP - ppublish PH - 2015/06/09 [received] PH - 2015/08/13 [revised] PH - 2015/08/21 [accepted] LG - English EP - 20150829 DP - 2016 Jan DC - 20160102 EZ - 2015/09/01 06:00 DA - 2016/07/21 06:00 DT - 2015/09/01 06:00 YR - 2016 ED - 20160720 RD - 20160102 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26321172 <74. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26241686 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Collins GG AU - Gadzinski JA AU - Fitzgerald GD AU - Sheran J AU - Wagner S AU - Edelstein S AU - Mueller ER FA - Collins, Gretchen G FA - Gadzinski, Jill A FA - Fitzgerald, Garrett D FA - Sheran, Jordan FA - Wagner, Sarah FA - Edelstein, Steven FA - Mueller, Elizabeth R IN - Collins, Gretchen G. Department of Obstetrics and Gynecology, Loyola University Chicago Stritch School of Medicine, Maywood, IL. Electronic address: gg.garbe@gmail.com. IN - Gadzinski, Jill A. Department of Obstetrics and Gynecology, Loyola University Chicago Stritch School of Medicine, Maywood, IL. IN - Fitzgerald, Garrett D. Department of Obstetrics and Gynecology, Loyola University Chicago Stritch School of Medicine, Maywood, IL. IN - Sheran, Jordan. Department of Obstetrics and Gynecology, Loyola University Chicago Stritch School of Medicine, Maywood, IL. IN - Wagner, Sarah. Department of Obstetrics and Gynecology, Loyola University Chicago Stritch School of Medicine, Maywood, IL. IN - Edelstein, Steven. Department of Anesthesia, Loyola University Chicago Stritch School of Medicine, Maywood, IL. IN - Mueller, Elizabeth R. Department of Urology and Obstetrics and Gynecology, Loyola University Chicago Stritch School of Medicine, Maywood, IL. TI - Surgical Pain Control With Ropivacaine by Atomized Delivery (Spray): A Randomized Controlled Trial. SO - Journal of Minimally Invasive Gynecology. 23(1):40-5, 2016 Jan AS - J Minim Invasive Gynecol. 23(1):40-5, 2016 Jan NJ - Journal of minimally invasive gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101235322 IO - J Minim Invasive Gynecol SB - Index Medicus CP - United States MH - Adult MH - *Amides/ad [Administration & Dosage] MH - *Anesthetics, Local/ad [Administration & Dosage] MH - Double-Blind Method MH - Female MH - *Gynecologic Surgical Procedures/ae [Adverse Effects] MH - Humans MH - Injections, Intraperitoneal MH - Insufflation/is [Instrumentation] MH - Middle Aged MH - *Nebulizers and Vaporizers MH - Pain Measurement MH - *Pain, Postoperative/dt [Drug Therapy] MH - Patient Satisfaction MH - Treatment Outcome KW - Gynecology; Hysterectomy; Pain; Ropivacaine AB - STUDY OBJECTIVE: To investigate the role of intraoperative atomized intraperitoneal ropivacaine (AIR) as an adjuvant to anesthetic agents at the time of minimally invasive pelvic surgery. AB - DESIGN: Double-blind, randomized controlled trial. AB - DESIGN: AB - CLASSIFICATION: Randomized controlled trial (Canadian Task Force classification I). AB - SETTING: Tertiary care teaching hospital. AB - PARTICIPANTS: Fifty-five patients who underwent laparoscopic and robotic gynecologic procedures. AB - INTERVENTION: Patients received AIR or atomized intraperitoneal saline (AIS) (dose, 2 mg/kg) immediately after the initiation of pneumoperitoneum. AB - MEASUREMENTS AND MAIN RESULTS: Visual analog scale (VAS) pain scores and narcotic use (in morphine equivalents) were collected and recorded at 2, 4, 8, and 12 hours postoperatively. AB - RESULTS: Fifty-five patients completed the study protocol and data collection, with 30 patients allocated to the AIS group and 25 patients allocated to the AIR group. Demographic and surgical variables did not vary between the groups, with the exception of median operative duration. Postoperative VAS scores at 2, 4, 8, and 12 postoperative hours were higher in the AIS group, but the difference failed to reach statistical significance. Narcotic use was also similar in the 2 groups. AB - CONCLUSION: The use of intraperitoneal ropivacaine was not associated with a statistically significant difference in patients' postoperative VAS scores. Thus, in contrast to findings of similar studies performed in general surgery, AIR might not confer a benefit in women undergoing minimally invasive gynecologic procedures. AB - Copyright © 2016 AAGL. Published by Elsevier Inc. All rights reserved. RN - 0 (Amides) RN - 0 (Anesthetics, Local) RN - 7IO5LYA57N (ropivacaine) ES - 1553-4669 IL - 1553-4650 DI - S1553-4650(15)00541-5 DO - https://dx.doi.org/10.1016/j.jmig.2015.07.018 PT - Journal Article PT - Randomized Controlled Trial ID - 26241686 [pubmed] ID - S1553-4650(15)00541-5 [pii] ID - 10.1016/j.jmig.2015.07.018 [doi] PP - ppublish PH - 2015/04/03 [received] PH - 2015/07/23 [revised] PH - 2015/07/24 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01480089 SL - https://clinicaltrials.gov/search/term=NCT01480089 LG - English EP - 20150801 DP - 2016 Jan DC - 20160102 EZ - 2015/08/05 06:00 DA - 2016/07/21 06:00 DT - 2015/08/05 06:00 YR - 2016 ED - 20160720 RD - 20160102 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26241686 <75. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26213181 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Horstmann M FA - Horstmann, Marcus IN - Horstmann, Marcus. Department of Urology, Jena University Hospital, Jena, Germany. marcushorstmann@gmx.ch. IN - Horstmann, Marcus. Department of Urology, Malteser Hospital St. Josefshospital, Krefeld, Germany. marcushorstmann@gmx.ch. TI - Editorial Comment to Transperitoneal versus extraperitoneal robot-assisted laparoscopic radical prostatectomy: A prospective single surgeon randomized comparative study. CM - Comment on: Int J Urol. 2015 Oct;22(10):916-21; PMID: 26212891 SO - International Journal of Urology. 22(10):922, 2015 Oct AS - Int J Urol. 22(10):922, 2015 Oct NJ - International journal of urology : official journal of the Japanese Urological Association PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - ce6, 9440237 IO - Int. J. Urol. SB - Index Medicus CP - Australia MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotic Surgical Procedures/mt [Methods] ES - 1442-2042 IL - 0919-8172 DO - https://dx.doi.org/10.1111/iju.12878 PT - Comment PT - Editorial ID - 26213181 [pubmed] ID - 10.1111/iju.12878 [doi] PP - ppublish LG - English EP - 20150726 DP - 2015 Oct DC - 20151006 EZ - 2015/07/28 06:00 DA - 2016/07/14 06:00 DT - 2015/07/28 06:00 YR - 2015 ED - 20160713 RD - 20151006 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26213181 <76. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26212891 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Akand M AU - Erdogru T AU - Avci E AU - Ates M FA - Akand, Murat FA - Erdogru, Tibet FA - Avci, Egemen FA - Ates, Mutlu IN - Akand, Murat. Department of Urology, School of Medicine, Selcuk University, Konya, Turkey. IN - Erdogru, Tibet. Departments of Urology and Minimally Invasive & Robotic Surgery, Memorial Atasehir Hospital, Istanbul, Turkey. IN - Avci, Egemen. Departments of Urology and Minimally Invasive & Robotic Surgery, Memorial Atasehir Hospital, Istanbul, Turkey. IN - Ates, Mutlu. Department of Urology, Memorial Antalya Hospital, Antalya, Turkey. TI - Transperitoneal versus extraperitoneal robot-assisted laparoscopic radical prostatectomy: A prospective single surgeon randomized comparative study. CM - Comment in: Int J Urol. 2015 Oct;22(10):922; PMID: 26213181 SO - International Journal of Urology. 22(10):916-21, 2015 Oct AS - Int J Urol. 22(10):916-21, 2015 Oct NJ - International journal of urology : official journal of the Japanese Urological Association PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - ce6, 9440237 IO - Int. J. Urol. SB - Index Medicus CP - Australia MH - Aged MH - Anesthesia MH - Blood Loss, Surgical MH - Eating MH - Erectile Dysfunction/et [Etiology] MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy/mt [Methods] MH - Length of Stay MH - Male MH - Middle Aged MH - Operative Time MH - Peritoneum/su [Surgery] MH - Prospective Studies MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures/mt [Methods] MH - Time Factors MH - Urinary Catheterization MH - Urinary Incontinence/et [Etiology] KW - extraperitoneal; prostate cancer; radical prostatectomy; robot-assisted laparoscopic radical prostatectomy; robotic surgery; transperitoneal AB - OBJECTIVES: To compare operative, pathological, and functional results of transperitoneal and extraperitoneal robot-assisted laparoscopic radical prostatectomy carried out by a single surgeon. AB - METHODS: After having experience with 32 transperitoneal laparoscopic radical prostatectomies, 317 extraperitoneal laparoscopic radical prostatectomies, 30 transperitoneal robot-assisted laparoscopic radical prostatectomies and 10 extraperitoneal robot-assisted laparoscopic radical prostatectomies, 120 patients with prostate cancer were enrolled in this prospective randomized study and underwent either transperitoneal or extraperitoneal robot-assisted laparoscopic radical prostatectomy. The main outcome parameters between the two study groups were compared. AB - RESULTS: No significant difference was found for age, body mass index, preoperative prostate-specific antigen, clinical and pathological stage, Gleason score on biopsy and prostatectomy specimen, tumor volume, positive surgical margin, and lymph node status. Transperitoneal robot-assisted laparoscopic radical prostatectomy had shorter trocar insertion time (16.0 vs 25.9 min for transperitoneal robot-assisted laparoscopic radical prostatectomy and extraperitoneal robot-assisted laparoscopic radical prostatectomy, P < 0.001), whereas extraperitoneal robot-assisted laparoscopic radical prostatectomy had shorter console time (101.5 vs 118.3 min, respectively, P < 0.001). Total operation time and total anesthesia time were found to be shorter in extraperitoneal robot-assisted laparoscopic radical prostatectomy, without statistical significance (200.9 vs 193.2 min; 221.8 vs 213.3 min, respectively). Estimated blood loss was found to be lower for extraperitoneal robot-assisted laparoscopic radical prostatectomy (P = 0.001). Catheterization and hospitalization times were observed to be shorter in extraperitoneal robot-assisted laparoscopic radical prostatectomy (7.3 vs 5.8 days and 3.1 vs 2.3 days for transperitoneal robot-assisted laparoscopic radical prostatectomy and extraperitoneal robot-assisted laparoscopic radical prostatectomy, respectively, P < 0.05). The time to oral diet was significantly shorter in extraperitoneal robot-assisted laparoscopic radical prostatectomy (32.3 vs 20.1 h, P = 0.031). Functional outcomes (continence and erection) and complication rates were similar in both groups. AB - CONCLUSIONS: Extraperitoneal robot-assisted laparoscopic radical prostatectomy seems to be a good alternative to transperitoneal robot-assisted laparoscopic radical prostatectomy with similar operative, pathological and functional results. As the surgical field remains away from the bowel, postoperative return to normal diet and early discharge can be favored. AB - Copyright © 2015 The Japanese Urological Association. ES - 1442-2042 IL - 0919-8172 DO - https://dx.doi.org/10.1111/iju.12854 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 26212891 [pubmed] ID - 10.1111/iju.12854 [doi] PP - ppublish PH - 2014/12/19 [received] PH - 2015/06/02 [accepted] LG - English EP - 20150726 DP - 2015 Oct DC - 20151006 EZ - 2015/07/28 06:00 DA - 2016/07/13 06:00 DT - 2015/07/28 06:00 YR - 2015 ED - 20160712 RD - 20151006 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26212891 <77. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26377929 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Liu Y AU - Ji WB AU - Wang HG AU - Luo Y AU - Wang XQ AU - Lv SC AU - Dong JH FA - Liu, Yang FA - Ji, Wen-Bin FA - Wang, Hong-Guang FA - Luo, Ying FA - Wang, Xian-Qiang FA - Lv, Shao-Cheng FA - Dong, Jia-Hong IN - Liu, Yang. Hepatobiliary Department, PLA General Hospital of China, Beijing, 100853, China. gdwk301@sina.com. IN - Ji, Wen-Bin. Hepatobiliary Department, PLA General Hospital of China, Beijing, 100853, China. Jiwenbin1999@126.com. IN - Wang, Hong-Guang. Hepatobiliary Department, PLA General Hospital of China, Beijing, 100853, China. Wanghongguang301@yahoo.cn. IN - Luo, Ying. Hepatobiliary Department, PLA General Hospital of China, Beijing, 100853, China. luoyingly@hotmail.com. IN - Wang, Xian-Qiang. Hepatobiliary Department, PLA General Hospital of China, Beijing, 100853, China. xqwang1017@qq.com. IN - Lv, Shao-Cheng. Hepatobiliary Department, PLA General Hospital of China, Beijing, 100853, China. Shaocheng0502@163.com. IN - Dong, Jia-Hong. Hepatobiliary Department, PLA General Hospital of China, Beijing, 100853, China. djh20150603@126.com. TI - Robotic spleen-preserving laparoscopic distal pancreatectomy: a single-centered Chinese experience. SO - World Journal of Surgical Oncology. 13:275, 2015 Sep 17 AS - World J Surg Oncol. 13:275, 2015 Sep 17 NJ - World journal of surgical oncology PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101170544 IO - World J Surg Oncol PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574193 SB - Index Medicus CP - England MH - Adult MH - Aged MH - China MH - Female MH - Follow-Up Studies MH - Humans MH - *Laparoscopy MH - Length of Stay MH - Male MH - Middle Aged MH - Neoplasm Staging MH - *Organ Sparing Treatments/mt [Methods] MH - *Pancreatectomy/mt [Methods] MH - Pancreatic Neoplasms/pa [Pathology] MH - *Pancreatic Neoplasms/su [Surgery] MH - Prognosis MH - *Robotic Surgical Procedures AB - BACKGROUND: Spleen-preserving laparoscopic distal pancreatectomy is technically challenging. New surgical robotic systems are now available and show promising outcomes but were very recently implemented in China. AB - METHODS: Seven patients underwent laparoscopic distal pancreatectomy using the da Vinci Robotic System (RDP) for benign or borderline malignant pancreatic tumors. Spleen preservation rate, blood loss, and operative complications were assessed. AB - RESULTS: Mean age was 44.6+/-13.7 years. Surgery was uneventful in all patients, without conversion to laparotomy. The surgical time (including anesthesia induction, robot docking, operation, and postoperative awaking time) was 460+/-154 min, while the operation time was 368+/-126 min. Blood losses were 200+/-110 mL. The minor (Clavien I+II) complication rate was 14.3%, and the major (Clavien III+IV) complication rate was 14.3 %, including hemorrhage and pancreatic leakage. The spleen preservation rate was 100%. All complications were successfully managed and cured. Intraoperative laparoscopic ultrasound examination successfully identified the correct surgical resection margins. Mean postoperative hospitalization was 8.7+/-6.6 days. No patient had to undergo a second pancreas surgery. Patients were followed up for a median of 6.8 months (range, 6 to 22 months). All patients survived and reported few discomforts. AB - CONCLUSIONS: RDP is feasible and allows the preservation of the splenic vessels. ES - 1477-7819 IL - 1477-7819 DI - 10.1186/s12957-015-0671-x DO - https://dx.doi.org/10.1186/s12957-015-0671-x PT - Clinical Study PT - Journal Article ID - 26377929 [pubmed] ID - 10.1186/s12957-015-0671-x [doi] ID - 10.1186/s12957-015-0671-x [pii] ID - PMC4574193 [pmc] PP - epublish PH - 2015/06/03 [received] PH - 2015/08/03 [accepted] LG - English EP - 20150917 DP - 2015 Sep 17 DC - 20150917 EZ - 2015/09/18 06:00 DA - 2016/07/09 06:00 DT - 2015/09/18 06:00 YR - 2015 ED - 20160707 RD - 20150919 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26377929 <78. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25761559 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Chen S AU - Chen JZ AU - Zhan Q AU - Deng XX AU - Shen BY AU - Peng CH AU - Li HW FA - Chen, Shi FA - Chen, Jiang-Zhi FA - Zhan, Qian FA - Deng, Xia-Xing FA - Shen, Bai-Yong FA - Peng, Cheng-Hong FA - Li, Hong-Wei IN - Chen, Shi. Department of General Surgery, Research Institute of Pancreatic Disease, Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China. wawljwalj@163.com. IN - Chen, Shi. Department of Hepatobiliary Surgery, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China. wawljwalj@163.com. IN - Chen, Jiang-Zhi. Department of General Surgery, Research Institute of Pancreatic Disease, Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China. IN - Chen, Jiang-Zhi. Department of Hepatobiliary Surgery, Union Hospital, Fujian Medical University, Fuzhou, China. IN - Zhan, Qian. Department of General Surgery, Research Institute of Pancreatic Disease, Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China. zhanxi80@hotmail.com. IN - Zhan, Qian. Department of General Surgery, Research Institute of Pancreatic Disease and Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, China. zhanxi80@hotmail.com. IN - Deng, Xia-Xing. Department of General Surgery, Research Institute of Pancreatic Disease, Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China. IN - Shen, Bai-Yong. Department of General Surgery, Research Institute of Pancreatic Disease, Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China. IN - Peng, Cheng-Hong. Department of General Surgery, Research Institute of Pancreatic Disease, Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China. chhpeng@yeah.net. IN - Peng, Cheng-Hong. Department of General Surgery, Research Institute of Pancreatic Disease and Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, China. chhpeng@yeah.net. IN - Li, Hong-Wei. Department of General Surgery, Research Institute of Pancreatic Disease, Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China. TI - Robot-assisted laparoscopic versus open pancreaticoduodenectomy: a prospective, matched, mid-term follow-up study. SO - Surgical Endoscopy. 29(12):3698-711, 2015 Dec AS - Surg Endosc. 29(12):3698-711, 2015 Dec NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adenocarcinoma/mo [Mortality] MH - *Adenocarcinoma/su [Surgery] MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Female MH - Follow-Up Studies MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Matched-Pair Analysis MH - Middle Aged MH - Pancreatic Neoplasms/mo [Mortality] MH - *Pancreatic Neoplasms/su [Surgery] MH - *Pancreaticoduodenectomy/mt [Methods] MH - Prospective Studies MH - *Robotic Surgical Procedures/mt [Methods] MH - Survival Analysis MH - Treatment Outcome MH - Young Adult KW - Learning curve; Minimally invasiveness; Pancreaticoduodenectomy; Prospective study; Robot-assisted laparoscopy; Safety profile AB - BACKGROUND: Robot-assisted laparoscopic pancreaticoduodenectomy is a novel minimally invasive surgery technique, and its effectiveness and safety remain unknown in patients with borderline malignant or malignant diseases. This study aimed to prospectively evaluate the effectiveness and safety of RLPD versus open PD (OPD). AB - METHODS: Between January 2010 and December 2013, 180 eligible patients were prospectively hospitalized for elective RLPD (n = 60) or OPD (n = 120). They were matched for tumor location, tumor type, tumor size, ASA classification, age, and sex. The main outcome measures included demographics, intraoperative variables, morbidity, postoperative recovery, and mid-term evaluation. AB - RESULTS: Over the study period, the RLPD group had a significantly longer but decreasing operative time (median 410 vs. 323 min; P < 0.001), less blood loss (median 400 vs. 500 mL; P = 0.005), better nutritional status recovery, expedited off-bed return to activity (3.2 vs. 4.8 d; P < 0.001), faster resumption of bowel movement (3.6 vs. 5.2 d; P < 0.001), and shorter hospital stay (20 vs. 25 d; P = 0.002) compared to the OPD group. The two groups had similar surgical morbidities and mortality as well as R0 resection rate and number of lymph nodes resected. Among patients with pancreatic adenocarcinoma, the two groups had similar overall and disease-free survival (ACTRN12614000299606). AB - CONCLUSIONS: This first largest, prospective matched study demonstrated that for treating selected borderline and malignant pathologies, RLPD was associated with a significant learning curve effect and expedited postoperative recovery, but had a surgical and oncological safety profile similar to OPD. ES - 1432-2218 IL - 0930-2794 DI - 10.1007/s00464-015-4140-y DO - https://dx.doi.org/10.1007/s00464-015-4140-y PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 25761559 [pubmed] ID - 10.1007/s00464-015-4140-y [doi] ID - 10.1007/s00464-015-4140-y [pii] PP - ppublish PH - 2014/07/16 [received] PH - 2015/02/22 [accepted] SI - ANZCTR SA - ANZCTR/ACTRN12614000299606 LG - English EP - 20150312 DP - 2015 Dec DC - 20151120 EZ - 2015/03/13 06:00 DA - 2016/07/09 06:00 DT - 2015/03/13 06:00 YR - 2015 ED - 20160707 RD - 20151120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25761559 <79. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25620765 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Neuburger PJ AU - Ngai JY AU - Chacon MM AU - Luria B AU - Manrique-Espinel AM AU - Kline RP AU - Grossi EA AU - Loulmet DF FA - Neuburger, Peter J FA - Ngai, Jennie Y FA - Chacon, M Megan FA - Luria, Brent FA - Manrique-Espinel, Ana Maria FA - Kline, Richard P FA - Grossi, Eugene A FA - Loulmet, Didier F IN - Neuburger, Peter J. Department of Anesthesiology. Electronic address: peter.neuburger@nyumc.org. IN - Ngai, Jennie Y. Department of Anesthesiology. IN - Chacon, M Megan. Department of Anesthesiology. IN - Luria, Brent. Department of Anesthesiology. IN - Manrique-Espinel, Ana Maria. Department of Anesthesiology. IN - Kline, Richard P. Department of Anesthesiology. IN - Grossi, Eugene A. Department of Cardiothoracic Surgery, NYU Langone Medical Center, New York, New York. IN - Loulmet, Didier F. Department of Cardiothoracic Surgery, NYU Langone Medical Center, New York, New York. TI - A Prospective Randomized Study of Paravertebral Blockade in Patients Undergoing Robotic Mitral Valve Repair. SO - Journal of Cardiothoracic & Vascular Anesthesia. 29(4):930-6, 2015 Aug AS - J Cardiothorac Vasc Anesth. 29(4):930-6, 2015 Aug NJ - Journal of cardiothoracic and vascular anesthesia PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - a6i, 9110208 IO - J. Cardiothorac. Vasc. Anesth. SB - Index Medicus CP - United States MH - Aged MH - Female MH - *Heart Valve Prosthesis Implantation/ae [Adverse Effects] MH - Humans MH - Male MH - Middle Aged MH - *Mitral Valve Insufficiency/dg [Diagnostic Imaging] MH - *Mitral Valve Insufficiency/su [Surgery] MH - *Nerve Block/mt [Methods] MH - Pain, Postoperative/et [Etiology] MH - *Pain, Postoperative/pc [Prevention & Control] MH - Prospective Studies MH - *Robotic Surgical Procedures/ae [Adverse Effects] MH - Ultrasonography KW - minimally invasive cardiac surgery; mitral valve repair; paravertebral block; regional anesthesia; robotic AB - OBJECTIVE: The aim of this study was to evaluate the addition of paravertebral blockade to general anesthesia in patients undergoing robotic mitral valve repair. AB - DESIGN: A randomized, prospective trial. AB - SETTING: A single tertiary referral academic medical center. AB - PARTICIPANTS: 60 patients undergoing robotic mitral valve surgery. AB - INTERVENTIONS: Patients were randomized to receive 4-level paravertebral blockade with 0.5% bupivicaine before induction of general anesthesia. All patients were given a fentanyl patient-controlled analgesia upon arrival to the intensive care unit, and visual analog scale pain scores were queried for 24 hours. On postoperative day 2, patients were given an anesthesia satisfaction survey. AB - MEASUREMENTS AND MAIN RESULTS: After obtaining institutional review board approval, surgical and anesthetic data were recorded perioperatively and compared between groups. Compared to general anesthesia alone, patients receiving paravertebral blockade and general anesthesia reported significantly less postoperative pain and required fewer narcotics intraoperatively and postoperatively. Patients receiving paravertebral blockade also reported significantly higher satisfaction with anesthesia. Successful extubation in the operating room at the conclusion of surgery was 90% and similar in both groups. Hospital length of stay also was similar. No adverse reactions were reported. AB - CONCLUSIONS: The addition of paravertebral blockade to general anesthesia appears safe and can reduce postoperative pain and narcotic usage in patients undergoing minimally invasive cardiac surgery. These findings were similar to previous studies of patients undergoing thoracic procedures. Paravertebral blockade alone likely does not reduce hospital length of stay. This may be more closely related to early extubation, which is possible with or without paravertebral blockade. AB - Copyright © 2015 Elsevier Inc. All rights reserved. ES - 1532-8422 IL - 1053-0770 DI - S1053-0770(14)00477-7 DO - https://dx.doi.org/10.1053/j.jvca.2014.10.010 PT - Journal Article PT - Randomized Controlled Trial ID - 25620765 [pubmed] ID - S1053-0770(14)00477-7 [pii] ID - 10.1053/j.jvca.2014.10.010 [doi] PP - ppublish PH - 2014/08/04 [received] LG - English EP - 20150123 DP - 2015 Aug DC - 20150817 EZ - 2015/01/27 06:00 DA - 2016/06/30 06:00 DT - 2015/01/27 06:00 YR - 2015 ED - 20160629 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25620765 <80. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25791063 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Chen S AU - Zhan Q AU - Chen JZ AU - Jin JB AU - Deng XX AU - Chen H AU - Shen BY AU - Peng CH AU - Li HW FA - Chen, Shi FA - Zhan, Qian FA - Chen, Jiang-zhi FA - Jin, Jia-bin FA - Deng, Xia-xing FA - Chen, Hao FA - Shen, Bai-yong FA - Peng, Cheng-hong FA - Li, Hong-wei IN - Chen, Shi. Department of General Surgery, Research Institute of Pancreatic Disease, Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Chen, Shi. Department of Hepatobiliary Surgery, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, People's Republic of China. IN - Zhan, Qian. Department of General Surgery, Research Institute of Pancreatic Disease, Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Chen, Jiang-zhi. Department of General Surgery, Research Institute of Pancreatic Disease, Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Chen, Jiang-zhi. Department of Hepatobiliary Surgery, Union Hospital, Fujian Medical University, Fuzhou, People's Republic of China. IN - Jin, Jia-bin. Department of General Surgery, Research Institute of Pancreatic Disease, Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Deng, Xia-xing. Department of General Surgery, Research Institute of Pancreatic Disease, Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Chen, Hao. Department of General Surgery, Research Institute of Pancreatic Disease, Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Shen, Bai-yong. Department of General Surgery, Research Institute of Pancreatic Disease, Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. ruijinsby@163.com. IN - Peng, Cheng-hong. Department of General Surgery, Research Institute of Pancreatic Disease, Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. chhpeng@yeah.net. IN - Li, Hong-wei. Department of General Surgery, Research Institute of Pancreatic Disease, Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. TI - Robotic approach improves spleen-preserving rate and shortens postoperative hospital stay of laparoscopic distal pancreatectomy: a matched cohort study. SO - Surgical Endoscopy. 29(12):3507-18, 2015 Dec AS - Surg Endosc. 29(12):3507-18, 2015 Dec NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adult MH - Aged MH - Analysis of Variance MH - Blood Loss, Surgical/sn [Statistics & Numerical Data] MH - Blood Transfusion/sn [Statistics & Numerical Data] MH - Cohort Studies MH - Female MH - Humans MH - *Laparoscopy/mt [Methods] MH - Length of Stay/sn [Statistics & Numerical Data] MH - Male MH - Middle Aged MH - Operative Time MH - *Organ Sparing Treatments/mt [Methods] MH - Pancreatectomy/ae [Adverse Effects] MH - *Pancreatectomy/mt [Methods] MH - Pancreatic Fistula/et [Etiology] MH - Pancreatic Neoplasms/mo [Mortality] MH - *Pancreatic Neoplasms/su [Surgery] MH - Postoperative Period MH - Reoperation/sn [Statistics & Numerical Data] MH - *Robotic Surgical Procedures MH - *Spleen/su [Surgery] MH - *Surgery, Computer-Assisted/mt [Methods] MH - Treatment Outcome KW - Laparoscopic distal pancreatectomy; Matched cohort study; Minimal invasiveness; Robotic assistance; Spleen preservation AB - BACKGROUND: Spleen preservation (SP) is beneficial for patients undergoing distal pancreatectomy of benign and borderline tumors; however, the conventional laparoscopy approach (C-LDP) is less effective in controlling splenic vessel bleeding. The benefits of the robotic-assisted approach (RA-LDP) in SP have not been clearly described. This study aimed to evaluate whether a robotic approach could improve SP rate and effectiveness/safety profile of laparoscopic distal pancreatectomy (LDP). AB - METHODS: Matched for scheduled SP, age, sex, ASA classification, tumor size, tumor location, and pathological type, 69 patients undergoing RA-LDP and 50 undergoing C-LDP between January 2005 and May 2014 were included. Main outcome measures included SP rate, operative time (OT), blood loss, transfusion frequency, morbidity, postoperative hospital stay (PHS), and oncologic safety. AB - RESULTS: Among matched patients scheduled for SP, RA-LDP was associated with significantly higher overall (95.7 vs. 39.4%) and Kimura SP rates (72.3 vs. 21.2%), shorter OT (median 120 vs. 200 min), less blood loss (median 100 vs. 300 mL), lower transfusion frequency (2.1 vs. 18.2%), and shorter mean PHS (10.2 vs. 14.5 days). Among matched patients scheduled for splenectomy, RA-LDP was associated with similar OT, blood loss, transfusion frequency, and PHS. The two approaches were similar in overall morbidity, frequency of pancreatic fistula, and oncologic outcome among patients undergoing splenectomy for malignant tumors. AB - CONCLUSIONS: RA-LDP was associated with a significantly better SP rate and reduced OT, blood loss, transfusion requirement, and PHS for patients undergoing SP compared to C-LDP, but offered less benefits for patients undergoing splenectomy. ES - 1432-2218 IL - 0930-2794 DI - 10.1007/s00464-015-4101-5 DO - https://dx.doi.org/10.1007/s00464-015-4101-5 PT - Journal Article ID - 25791063 [pubmed] ID - 10.1007/s00464-015-4101-5 [doi] ID - 10.1007/s00464-015-4101-5 [pii] PP - ppublish PH - 2014/09/25 [received] PH - 2015/01/26 [accepted] LG - English EP - 20150320 DP - 2015 Dec DC - 20151120 EZ - 2015/03/21 06:00 DA - 2016/06/29 06:00 DT - 2015/03/21 06:00 YR - 2015 ED - 20160628 RD - 20151120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25791063 <81. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26856215 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hoekstra M AU - Hessels L AU - Rienstra M AU - Yeh L AU - Lansink AO AU - Vogelzang M AU - van der Horst IC AU - van der Maaten JM AU - Mariani MA AU - de Smet AM AU - Struys MM AU - Zijlstra F AU - Nijsten MW FA - Hoekstra, Miriam FA - Hessels, Lara FA - Rienstra, Michiel FA - Yeh, Lu FA - Lansink, Annemieke Oude FA - Vogelzang, Mathijs FA - van der Horst, Iwan C C FA - van der Maaten, Joost M A A FA - Mariani, Massimo A FA - de Smet, Anne Marie G A FA - Struys, Michel M R F FA - Zijlstra, Felix FA - Nijsten, Maarten W IN - Hoekstra, Miriam. Department of Anesthesiology of the University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: m.hoekstra01@umcg.nl. IN - Hessels, Lara. Department of Critical Care of the University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: l.hessels@umcg.nl. IN - Rienstra, Michiel. Department of Cardiology of the University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: m.rienstra@umcg.nl. IN - Yeh, Lu. Department of Anesthesiology of the University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: l.yeh@umcg.nl. IN - Lansink, Annemieke Oude. Department of Critical Care of the University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: a.oudelansink@umcg.nl. IN - Vogelzang, Mathijs. Department of Critical Care of the University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: m.vogelzang@umcg.nl. IN - van der Horst, Iwan C C. Department of Critical Care of the University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: i.c.c.van.der.horst@umcg.nl. IN - van der Maaten, Joost M A A. Department of Anesthesiology of the University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Department of Critical Care of the University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: j.m.a.a.van.der.maaten@umcg.nl. IN - Mariani, Massimo A. Department of Cardiothoracic Surgery of the University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: m.mariani@umcg.nl. IN - de Smet, Anne Marie G A. Department of Critical Care of the University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: a.m.g.a.de.smet@umcg.nl. IN - Struys, Michel M R F. Department of Anesthesiology of the University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: m.m.r.f.struys@umcg.nl. IN - Zijlstra, Felix. Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands. Electronic address: f.zijlstra1@erasmc.nl. IN - Nijsten, Maarten W. Department of Critical Care of the University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: m.w.n.nijsten@umcg.nl. TI - Computer-guided normal-low versus normal-high potassium control after cardiac surgery: No impact on atrial fibrillation or atrial flutter. SO - American Heart Journal. 172:45-52, 2016 Feb AS - Am Heart J. 172:45-52, 2016 Feb NJ - American heart journal PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 0370465 IO - Am. Heart J. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Atrial Fibrillation/ep [Epidemiology] MH - *Atrial Fibrillation/pc [Prevention & Control] MH - Atrial Flutter/ep [Epidemiology] MH - *Atrial Flutter/pc [Prevention & Control] MH - *Cardiac Surgical Procedures MH - Double-Blind Method MH - *Drug Monitoring/mt [Methods] MH - Electrocardiography MH - Female MH - Follow-Up Studies MH - Heart Diseases/bl [Blood] MH - *Heart Diseases/su [Surgery] MH - Humans MH - Incidence MH - Male MH - Netherlands/ep [Epidemiology] MH - *Postoperative Care/mt [Methods] MH - *Potassium/ad [Administration & Dosage] MH - Potassium/pk [Pharmacokinetics] MH - Prospective Studies AB - INTRODUCTION: This study was designed to determine the effect of 2 different potassium regulation strategies with different targets (within the reference range) on atrial fibrillation (AF) or atrial flutter (AFL) in a cohort of intensive care unit patients after cardiac surgery. AB - METHODS: The GRIP-COMPASS study was a prospective double-blinded interventional study in 910 patients after cardiac surgery (coronary artery bypass grafting and/or valvular surgery). Patients were assigned to either the normal-low potassium target (nLP group, 4.0 mmol/L) or the normal-high potassium target (nHP group, 4.5 mmol/L) in alternating blocks of 50 patients. Potassium levels were regulated using a validated computer-assisted potassium replacement protocol (GRIP-II). The primary end point was the incidence of AF/AFL on a 12-lead electrocardiogram during the first postoperative week. AB - RESULTS: Of the 910 patients, 447 were assigned to the nLP group; and 463, to the nHP group, with no baseline differences between the 2 groups. The mean daily administered dose of potassium was 30 +/- 23 mmol (nLP) versus 52 +/- 27 mmol (nHP) (P < .001), which resulted in mean intensive care unit potassium concentration of 4.22 +/- 0.36 mmol/L and 4.33 +/- 0.34 mmol/L, respectively (P < .001). The incidence of AF/AFL after cardiac surgery did not differ: 38% in the nLP group and 41% in the nHP group. Also in several subgroups (eg, patients not known with prior AF/AFL or with valve surgery), there were no differences. AB - CONCLUSIONS: There were no differences in incidence of AF/AFL with 2 potassium regulation strategies with different potassium targets and different amounts of potassium administered in patients after cardiac surgery. AB - Copyright © 2015 Elsevier Inc. All rights reserved. RN - RWP5GA015D (Potassium) ES - 1097-6744 IL - 0002-8703 DI - S0002-8703(15)00656-0 DO - https://dx.doi.org/10.1016/j.ahj.2015.10.020 PT - Journal Article PT - Randomized Controlled Trial ID - 26856215 [pubmed] ID - S0002-8703(15)00656-0 [pii] ID - 10.1016/j.ahj.2015.10.020 [doi] PP - ppublish PH - 2014/11/26 [received] PH - 2015/10/29 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01085071 SL - https://clinicaltrials.gov/search/term=NCT01085071 LG - English EP - 20151111 DP - 2016 Feb DC - 20160209 EZ - 2016/02/10 06:00 DA - 2016/06/15 06:00 DT - 2016/02/10 06:00 YR - 2016 ED - 20160614 RD - 20160209 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26856215 <82. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26855394 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Mark-Christensen A AU - Pachler FR AU - Norager CB AU - Jepsen P AU - Laurberg S AU - Tottrup A FA - Mark-Christensen, Anders FA - Pachler, Frederik Ronne FA - Norager, Charlotte Buchard FA - Jepsen, Peter FA - Laurberg, Soren FA - Tottrup, Anders IN - Mark-Christensen, Anders. 1 Department of Surgery P, Aarhus University Hospital, Aarhus, Denmark 2 Department of Gastroenterology and Hepatology, Aarhus University Hospital, Aarhus, Denmark 3 Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark. TI - Short-term Outcome of Robot-assisted and Open IPAA: An Observational Single-center Study. SO - Diseases of the Colon & Rectum. 59(3):201-7, 2016 Mar AS - Dis Colon Rectum. 59(3):201-7, 2016 Mar NJ - Diseases of the colon and rectum PI - Journal available in: Print PI - Citation processed from: Internet JC - eab, 0372764 IO - Dis. Colon Rectum SB - Index Medicus CP - United States MH - Adult MH - *Colitis, Ulcerative/su [Surgery] MH - Female MH - Follow-Up Studies MH - Humans MH - *Laparoscopy/mt [Methods] MH - *Laparotomy/mt [Methods] MH - Male MH - *Proctocolectomy, Restorative/mt [Methods] MH - Retrospective Studies MH - *Robotics/mt [Methods] MH - Time Factors MH - Treatment Outcome AB - BACKGROUND: The potential advantages of robot-assisted laparoscopy are being increasingly investigated, although data on its efficacy in benign colorectal surgery are scarce. AB - OBJECTIVE: We compared the early postoperative outcome in robot-assisted IPAA with open surgery procedures. AB - DESIGN: This was an observational study based on prospectively collected data obtained from chart reviews. AB - SETTING: The single-center data set covers patients operated on from January 13, 2004, to September 16, 2014, at a specialist center. AB - PATIENTS: Patients with ulcerative colitis undergoing IPAA surgery were included. AB - MAIN OUTCOME MEASURES: Study end points included the duration of operation, admission length, complications (Clavien-Dindo), reoperations, and readmissions. AB - RESULTS: Eighty-one robot-assisted and 170 open IPAA procedures were performed. The duration of operation was significantly longer for robot-assisted laparoscopic procedures (mean difference, 154 minutes; CI, 140-170). During a mean follow-up of 102 days, no significant differences in the distribution of complications were found (Spearman p = 0.12; p = 0.07), and no postoperative deaths occurred in either group. Postoperative admission length was shorter following robot-assisted procedures (mean difference, -1.9; CI, -3.5 to -0.3), whereas 40% of patients were readmitted, compared with 26% of patients who had open surgery (OR, 1.9; CI, 1.1-3.4). Pouch failure occurred in 3 patients (1 following robot-assisted laparoscopy; 2 following open surgery). On multivariate regression analyses, robot-assisted laparoscopy was associated with a significantly longer duration of operation (mean difference, 159 minutes; CI, 144-174), and more readmissions for any cause (OR, 2; CI, 1.1-3.7). AB - LIMITATIONS: This was a nonrandomized, single-center observational study. AB - CONCLUSION: In this implementation phase, robot-assisted IPAA surgery offers acceptable short-term outcomes. The limitations of this observational study call for randomized controlled trials with long-term follow-up and exploration of functional results. ES - 1530-0358 IL - 0012-3706 DI - 00003453-201603000-00007 DO - https://dx.doi.org/10.1097/DCR.0000000000000540 PT - Comparative Study PT - Journal Article PT - Observational Study ID - 26855394 [pubmed] ID - 10.1097/DCR.0000000000000540 [doi] ID - 00003453-201603000-00007 [pii] PP - ppublish LG - English DP - 2016 Mar DC - 20160209 EZ - 2016/02/09 06:00 DA - 2016/06/15 06:00 DT - 2016/02/09 06:00 YR - 2016 ED - 20160614 RD - 20160209 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26855394 <83. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27201725 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - PubMed-not-MEDLINE AU - Turchetti G AU - Pierotti F AU - Palla I AU - Manetti S AU - Cuschieri A FA - Turchetti, G FA - Pierotti, F FA - Palla, I FA - Manetti, S FA - Cuschieri, A IN - Turchetti, G. Scuola Superiore Sant'Anna, Pisa, Italy. IN - Pierotti, F. Scuola Superiore Sant'Anna, Pisa, Italy. IN - Palla, I. Scuola Superiore Sant'Anna, Pisa, Italy. IN - Manetti, S. Scuola Superiore Sant'Anna, Pisa, Italy. IN - Cuschieri, A. Scuola Superiore Sant'Anna, Pisa, Italy. TI - The Quality of Life of Patients Treated With Robotic Versus Traditional Surgery Results From An Italian Observational Multicenter Study. SO - Value in Health. 17(7):A538-9, 2014 Nov AS - Value Health. 17(7):A538-9, 2014 Nov NJ - Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 100883818 IO - Value Health CP - United States ES - 1524-4733 IL - 1098-3015 DI - S1098-3015(14)03656-0 DO - https://dx.doi.org/10.1016/j.jval.2014.08.1726 PT - Journal Article ID - 27201725 [pubmed] ID - S1098-3015(14)03656-0 [pii] ID - 10.1016/j.jval.2014.08.1726 [doi] PP - ppublish LG - English EP - 20141026 DP - 2014 Nov DC - 20160521 EZ - 2016/05/21 06:00 DA - 2014/11/01 00:01 DT - 2014/11/01 00:00 YR - 2014 ED - 20160610 RD - 20160521 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27201725 <84. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26817867 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hou CP AU - Lin YH AU - Hsu YC AU - Chen CL AU - Chang PL AU - Tsui KH FA - Hou, Chen-Pang FA - Lin, Yu-Hsiang FA - Hsu, Yu-Chao FA - Chen, Chien-Lun FA - Chang, Phei-Lang FA - Tsui, Ke-Hung IN - Hou, Chen-Pang. From the Department of Urology, Chang Gung Memorial Hospital at Linkou (K-HT, P-LC); School of Medicine, Chang Gung University (K-H T, P-LC, C-PH, Y-HL, Y-CH, C-LC); Kwei-Shan, Tao-Yuan, Taiwan. TI - Using a Harmonic Scalpel "Drilling and Clamping" Method to Implement Zero Ischemic Robotic-assisted Partial Nephrectomy: An Observation Case Report Study. SO - Medicine. 95(3):e2349, 2016 Jan AS - Medicine (Baltimore). 95(3):e2349, 2016 Jan NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998241 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - Female MH - Humans MH - *Ischemia/pc [Prevention & Control] MH - *Kidney/bs [Blood Supply] MH - *Kidney Neoplasms/su [Surgery] MH - Male MH - Middle Aged MH - Nephrectomy/ae [Adverse Effects] MH - *Nephrectomy/mt [Methods] MH - Postoperative Complications MH - Prospective Studies MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures/mt [Methods] MH - Tomography, X-Ray Computed MH - Treatment Outcome AB - Robot-assisted partial nephrectomy (RAPN) has gradually become a popular minimally invasive nephron-sparing surgical option for small renal tumors. Ischemic injury should be minimized because it impacts renal function outcomes following partial nephrectomy. Herein, the authors detail the technique and present initial perioperative outcomes of our novel harmonic scalpel "drilling and clamping" method to implement zero-ischemic RAPN. The authors prospectively collected baseline and perioperative data of patients who underwent zero ischemic RAPN performed by our harmonic scalpel "drilling and clamping" method. From April 2012 to December 2014, a total of 19 consecutive zero ischemic RAPN procedures were performed by a single surgeon. For 18 of the 19 patients, RAPN using our harmonic scalpel "Drilling and Clamping" method was successfully completed without the need for hilar clamping. The median tumor size was 3.4 cm (range: 1.8-6.2); operative time was 3.2 hours (range: 1.9-4.5); blood loss was 100 mL (range: 30-950); and postoperative hospital stay was 4 days (3-26). One patient required intraoperative blood transfusion. Two patients had intra or postoperative complications: 1 was converted to traditional laparotomy because of massive bleeding, whereas another had postoperative stress ulcer. Pathology confirmed renal cell carcinoma in 13 patients (63.2%), angiomyolipoma in 6 patients: (31.5%), and oncocytoma in 1 patient (5.3%). Mean pre- and postoperative serum creatinine (0.82 mg/dL and 0.85 mg/dL, respectively), estimated glomerular filtration rate (84.12 and 82.18, respectively), and hemoglobin (13.27 g/dL and 12.71 g/dL, respectively) were comparable. The authors present a novel zero-ischemic technique for RAPN. They believe that this technique is feasible and reproducible. ES - 1536-5964 IL - 0025-7974 DI - 00005792-201601190-00008 DO - https://dx.doi.org/10.1097/MD.0000000000002349 PT - Case Reports PT - Journal Article PT - Observational Study PT - Research Support, Non-U.S. Gov't ID - 26817867 [pubmed] ID - 10.1097/MD.0000000000002349 [doi] ID - 00005792-201601190-00008 [pii] ID - PMC4998241 [pmc] PP - ppublish LG - English DP - 2016 Jan DC - 20160128 EZ - 2016/01/29 06:00 DA - 2016/06/10 06:00 DT - 2016/01/29 06:00 YR - 2016 ED - 20160609 RD - 20160904 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26817867 <85. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26817867 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hou CP AU - Lin YH AU - Hsu YC AU - Chen CL AU - Chang PL AU - Tsui KH FA - Hou, Chen-Pang FA - Lin, Yu-Hsiang FA - Hsu, Yu-Chao FA - Chen, Chien-Lun FA - Chang, Phei-Lang FA - Tsui, Ke-Hung IN - Hou, Chen-Pang. From the Department of Urology, Chang Gung Memorial Hospital at Linkou (K-HT, P-LC); School of Medicine, Chang Gung University (K-H T, P-LC, C-PH, Y-HL, Y-CH, C-LC); Kwei-Shan, Tao-Yuan, Taiwan. TI - Using a Harmonic Scalpel "Drilling and Clamping" Method to Implement Zero Ischemic Robotic-assisted Partial Nephrectomy: An Observation Case Report Study. SO - Medicine. 95(3):e2349, 2016 Jan AS - Medicine (Baltimore). 95(3):e2349, 2016 Jan NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998241 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - Female MH - Humans MH - *Ischemia/pc [Prevention & Control] MH - *Kidney/bs [Blood Supply] MH - *Kidney Neoplasms/su [Surgery] MH - Male MH - Middle Aged MH - Nephrectomy/ae [Adverse Effects] MH - *Nephrectomy/mt [Methods] MH - Postoperative Complications MH - Prospective Studies MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures/mt [Methods] MH - Tomography, X-Ray Computed MH - Treatment Outcome AB - Robot-assisted partial nephrectomy (RAPN) has gradually become a popular minimally invasive nephron-sparing surgical option for small renal tumors. Ischemic injury should be minimized because it impacts renal function outcomes following partial nephrectomy. Herein, the authors detail the technique and present initial perioperative outcomes of our novel harmonic scalpel "drilling and clamping" method to implement zero-ischemic RAPN. The authors prospectively collected baseline and perioperative data of patients who underwent zero ischemic RAPN performed by our harmonic scalpel "drilling and clamping" method. From April 2012 to December 2014, a total of 19 consecutive zero ischemic RAPN procedures were performed by a single surgeon. For 18 of the 19 patients, RAPN using our harmonic scalpel "Drilling and Clamping" method was successfully completed without the need for hilar clamping. The median tumor size was 3.4 cm (range: 1.8-6.2); operative time was 3.2 hours (range: 1.9-4.5); blood loss was 100 mL (range: 30-950); and postoperative hospital stay was 4 days (3-26). One patient required intraoperative blood transfusion. Two patients had intra or postoperative complications: 1 was converted to traditional laparotomy because of massive bleeding, whereas another had postoperative stress ulcer. Pathology confirmed renal cell carcinoma in 13 patients (63.2%), angiomyolipoma in 6 patients: (31.5%), and oncocytoma in 1 patient (5.3%). Mean pre- and postoperative serum creatinine (0.82 mg/dL and 0.85 mg/dL, respectively), estimated glomerular filtration rate (84.12 and 82.18, respectively), and hemoglobin (13.27 g/dL and 12.71 g/dL, respectively) were comparable. The authors present a novel zero-ischemic technique for RAPN. They believe that this technique is feasible and reproducible. CI - The authors have no funding and conflicts of interest to disclose. ES - 1536-5964 IL - 0025-7974 DI - 00005792-201601190-00008 DO - https://dx.doi.org/10.1097/MD.0000000000002349 PT - Case Reports PT - Journal Article PT - Observational Study PT - Research Support, Non-U.S. Gov't ID - 26817867 [pubmed] ID - 10.1097/MD.0000000000002349 [doi] ID - 00005792-201601190-00008 [pii] ID - PMC4998241 [pmc] PP - ppublish LG - English DP - 2016 Jan DC - 20160128 EZ - 2016/01/29 06:00 DA - 2016/06/10 06:00 DT - 2016/01/29 06:00 YR - 2016 ED - 20160609 RD - 20170224 UP - 20170228 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=26817867 <86. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26476808 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ramlawi B AU - Leja MJ AU - Abu Saleh WK AU - Al Jabbari O AU - Benjamin R AU - Ravi V AU - Shapira OM AU - Blackmon SH AU - Bruckner BA AU - Reardon MJ FA - Ramlawi, Basel FA - Leja, Monika J FA - Abu Saleh, Walid K FA - Al Jabbari, Odeaa FA - Benjamin, Robert FA - Ravi, Vinod FA - Shapira, Oz M FA - Blackmon, Shanda H FA - Bruckner, Brian A FA - Reardon, Michael J IN - Ramlawi, Basel. Department of Cardiovascular Surgery, Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas. IN - Leja, Monika J. Department of Cardiology, University of Michigan, Ann Arbor, Michigan. IN - Abu Saleh, Walid K. Department of Cardiovascular Surgery, Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas. IN - Al Jabbari, Odeaa. Department of Cardiovascular Surgery, Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas. IN - Benjamin, Robert. Department of Sarcoma Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas. IN - Ravi, Vinod. Department of Sarcoma Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas. IN - Shapira, Oz M. Department of Cardiothoracic Surgery, Haddasah Hebrew University Medical Center, Jerusalem, Israel. IN - Blackmon, Shanda H. Department of Thoracic Surgery, Mayo Clinic, Rochester, Minnesota. IN - Bruckner, Brian A. Department of Cardiovascular Surgery, Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas. IN - Reardon, Michael J. Department of Cardiovascular Surgery, Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas. Electronic address: mreardon@houstonmethodist.org. TI - Surgical Treatment of Primary Cardiac Sarcomas: Review of a Single-Institution Experience. SO - Annals of Thoracic Surgery. 101(2):698-702, 2016 Feb AS - Ann Thorac Surg. 101(2):698-702, 2016 Feb NJ - The Annals of thoracic surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 15030100R IO - Ann. Thorac. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - Netherlands MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Cardiac Surgical Procedures MH - Female MH - *Heart Neoplasms/su [Surgery] MH - Humans MH - Male MH - Middle Aged MH - Retrospective Studies MH - *Sarcoma/su [Surgery] MH - Young Adult AB - BACKGROUND: Primary cardiac sarcomas are rare, aggressive, and usually lethal. Surgical management protocols are not defined because of the lack of extensive experience in treating these patients. In this study, we reviewed our outcomes with primary cardiac sarcoma, and we make recommendations regarding management. AB - METHODS: Review of the Houston Methodist Hospital cardiac tumor database from 1990 to 2015 (25 years) yielded 131 primary cardiac evaluations of possible cardiac sarcoma. From these we identified 95 patients who underwent surgical excision. A computer search of cardiac sarcomas yielded 131 tumors that were coded as primary cardiac sarcoma or possible primary cardiac sarcoma. Retrospective data collection and clinical outcomes were evaluated for all 95 patients. Medical records and follow-up material were requested for all patients through clinic visits and contacting the physician of the patient, the hospital record department, and the cardiac tumor board after previous approval. The procedures were performed using an institutional review board-approved cardiac tumor protocol, and the patients gave full consent. AB - RESULTS: All 95 patients were diagnosed as having primary cardiac sarcoma by histologic appearance. Age ranged from 15 to 84 years at the time of presentation (mean, 44 years). Male patients made up 57% of the sample. The most common site for the cardiac sarcoma was the right atrium (37 patients) followed by the left atrium (31 patients). Postoperative 1-year mortality was 35% (33 patients). The most common tumor histologic type was angiosarcoma (40%) followed by spindle cell sarcoma (11%). AB - CONCLUSIONS: Primary cardiac sarcoma is a rare but lethal disease. Surgical intervention is associated with acceptable surgical mortality in this high-risk group of patients. AB - Copyright © 2016 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved. ES - 1552-6259 IL - 0003-4975 DI - S0003-4975(15)01347-8 DO - https://dx.doi.org/10.1016/j.athoracsur.2015.07.087 PT - Clinical Trial PT - Journal Article ID - 26476808 [pubmed] ID - S0003-4975(15)01347-8 [pii] ID - 10.1016/j.athoracsur.2015.07.087 [doi] PP - ppublish PH - 2015/05/27 [received] PH - 2015/07/23 [revised] PH - 2015/07/28 [accepted] LG - English EP - 20151021 DP - 2016 Feb DC - 20160118 EZ - 2015/10/19 06:00 DA - 2016/06/09 06:00 DT - 2015/10/20 06:00 YR - 2016 ED - 20160606 RD - 20160118 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26476808 <87. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25813692 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Rud E AU - Baco E AU - Klotz D AU - Rennesund K AU - Svindland A AU - Berge V AU - Lundeby E AU - Wessel N AU - Hoff JR AU - Berg RE AU - Diep L AU - Eggesbo HB AU - Eri LM FA - Rud, Erik FA - Baco, Eduard FA - Klotz, Dagmar FA - Rennesund, Kristin FA - Svindland, Aud FA - Berge, Viktor FA - Lundeby, Eskild FA - Wessel, Nicolai FA - Hoff, Jon-Roar FA - Berg, Rolf Eigil FA - Diep, Lien FA - Eggesbo, Heidi B FA - Eri, Lars Magne IN - Rud, Erik. Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway. Electronic address: p.e.rud@medisin.uio.no. IN - Baco, Eduard. Department of Urology, Oslo University Hospital, Oslo, Norway. IN - Klotz, Dagmar. Department of Pathology, Oslo University Hospital, Oslo, Norway. IN - Rennesund, Kristin. Department of Urology, Oslo University Hospital, Oslo, Norway. IN - Svindland, Aud. Department of Pathology, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway. IN - Berge, Viktor. Department of Urology, Oslo University Hospital, Oslo, Norway. IN - Lundeby, Eskild. Department of Urology, Oslo University Hospital, Oslo, Norway. IN - Wessel, Nicolai. Department of Urology, Oslo University Hospital, Oslo, Norway. IN - Hoff, Jon-Roar. Department of Urology, Oslo University Hospital, Oslo, Norway. IN - Berg, Rolf Eigil. Department of Urology, Oslo University Hospital, Oslo, Norway. IN - Diep, Lien. Department of Biostatistics, Epidemiology and Health Care Economics, Oslo University Hospital, Oslo, Norway. IN - Eggesbo, Heidi B. Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway. IN - Eri, Lars Magne. Department of Urology, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway. TI - Does preoperative magnetic resonance imaging reduce the rate of positive surgical margins at radical prostatectomy in a randomised clinical trial?. CM - Comment in: J Urol. 2016 Feb;195(2):349; PMID: 26852971 SO - European Urology. 68(3):487-96, 2015 Sep AS - Eur Urol. 68(3):487-96, 2015 Sep NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Aged MH - Humans MH - Logistic Models MH - *Magnetic Resonance Imaging/mt [Methods] MH - Male MH - Middle Aged MH - Neoplasm, Residual MH - Preoperative Care MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/pa [Pathology] MH - Prostatic Neoplasms/su [Surgery] MH - Robotic Surgical Procedures/mt [Methods] MH - *Surgery, Computer-Assisted/mt [Methods] KW - MRI; Preoperative; Prostate cancer; RCT; Randomised controlled trial; Surgical benefit; Surgical margins AB - BACKGROUND: Magnetic resonance imaging (MRI) has the potential to help the surgeon tailor radical prostatectomy (RP) more accurately according to the location and extent of the tumour and thereby reduce the rate of positive surgical margins (PSMs). AB - OBJECTIVE: To evaluate the benefit of performing MRI prior to RP. AB - DESIGN, SETTING, AND PARTICIPANTS: This single-institution randomised trial included 438 patients between December 2009 and June 2012 who were scheduled for robot-assisted laparoscopic prostatectomy. The study was registered (ClinicalTrials.gov identifier NCT01347320). AB - INTERVENTION: Patients were preoperatively randomly assigned to non-MRI or MRI groups. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: The primary end point was the difference in the PSM rates between the two groups. Secondary end points were the rates of PSMs in clinical subgroups. Summary statistics were extracted from descriptive analyses, chi-square, or Fisher exact test, and logistic regression was used to analyse the data according to the intention-to-treat principle. AB - RESULTS AND LIMITATIONS: A total of 216 patients were randomised to non-MRI; 222 were randomised to MRI. There were 49 cases (23%) of PSMs in the non-MRI group and 43 cases (19%) in the MRI group (p=0.4). The relative and absolute risk reduction was 15% and 4%, respectively. Patients with cT1 constituted 55% of the cohort, in which the rate of PSMs was 27% in the non-MRI group and 16% in the MRI group (p=0.035). The relative and absolute risk reduction was 41% and 11%, respectively. A limitation was suboptimal communication between the radiologist and urologist. AB - CONCLUSIONS: MRI prior to RP did not reduce the overall risk for PSMs in this patient cohort. However, at subgroup analysis we observed a possible benefit of MRI in patients with cT1. AB - PATIENT SUMMARY: This study could not demonstrate a definite benefit of performing magnetic resonance imaging before surgery for all patients. However, there was a possible improved result in patients in which physical examination could not detect the cancer. AB - Copyright © 2015 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(15)00204-3 DO - https://dx.doi.org/10.1016/j.eururo.2015.02.039 PT - Journal Article PT - Randomized Controlled Trial ID - 25813692 [pubmed] ID - S0302-2838(15)00204-3 [pii] ID - 10.1016/j.eururo.2015.02.039 [doi] PP - ppublish PH - 2014/11/12 [received] PH - 2015/02/27 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01347320 SL - https://clinicaltrials.gov/search/term=NCT01347320 LG - English EP - 20150323 DP - 2015 Sep DC - 20150818 EZ - 2015/03/28 06:00 DA - 2016/06/09 06:00 DT - 2015/03/31 06:00 YR - 2015 ED - 20160606 RD - 20160715 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25813692 <88. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25609318 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Aghazadeh MA AU - Jayaratna IS AU - Hung AJ AU - Pan MM AU - Desai MM AU - Gill IS AU - Goh AC FA - Aghazadeh, Monty A FA - Jayaratna, Isuru S FA - Hung, Andrew J FA - Pan, Michael M FA - Desai, Mihir M FA - Gill, Inderbir S FA - Goh, Alvin C IN - Aghazadeh, Monty A. Department of Urology, Methodist Institute for Technology, Innovation, and Education, Houston Methodist Hospital, 6560 Fannin Street, Suite 2100, Houston, TX, 77030, USA. IN - Aghazadeh, Monty A. Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA. IN - Jayaratna, Isuru S. USC Institute of Urology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. IN - Hung, Andrew J. USC Institute of Urology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. IN - Pan, Michael M. Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA. IN - Desai, Mihir M. USC Institute of Urology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. IN - Gill, Inderbir S. USC Institute of Urology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. IN - Goh, Alvin C. Department of Urology, Methodist Institute for Technology, Innovation, and Education, Houston Methodist Hospital, 6560 Fannin Street, Suite 2100, Houston, TX, 77030, USA. acg622@gmail.com. TI - External validation of Global Evaluative Assessment of Robotic Skills (GEARS). SO - Surgical Endoscopy. 29(11):3261-6, 2015 Nov AS - Surg Endosc. 29(11):3261-6, 2015 Nov NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adult MH - Animals MH - *Clinical Competence MH - Cross-Sectional Studies MH - Female MH - Humans MH - Male MH - Middle Aged MH - Observer Variation MH - Reproducibility of Results MH - *Robotic Surgical Procedures/ed [Education] MH - Surgeons/ed [Education] MH - Swine MH - Task Performance and Analysis MH - United States KW - Clinical competence; Education; Robotics; Validation studies AB - BACKGROUND: We demonstrate the construct validity, reliability, and utility of Global Evaluative Assessment of Robotic Skills (GEARS), a clinical assessment tool designed to measure robotic technical skills, in an independent cohort using an in vivo animal training model. AB - METHODS: Using a cross-sectional observational study design, 47 voluntary participants were categorized as experts (>30 robotic cases completed as primary surgeon) or trainees. The trainee group was further divided into intermediates (>5 but <30 cases) or novices (<5 cases). All participants completed a standardized in vivo robotic task in a porcine model. Task performance was evaluated by two expert robotic surgeons and self-assessed by the participants using the GEARS assessment tool. Kruskal-Wallis test was used to compare the GEARS performance scores to determine construct validity; Spearman's rank correlation measured interobserver reliability; and Cronbach's alpha was used to assess internal consistency. AB - RESULTS: Performance evaluations were completed on nine experts and 38 trainees (14 intermediate, 24 novice). Experts demonstrated superior performance compared to intermediates and novices overall and in all individual domains (p < 0.0001). In comparing intermediates and novices, the overall performance difference trended toward significance (p = 0.0505), while the individual domains of efficiency and autonomy were significantly different between groups (p = 0.0280 and 0.0425, respectively). Interobserver reliability between expert ratings was confirmed with a strong correlation observed (r = 0.857, 95 % CI [0.691, 0.941]). Experts and participant scoring showed less agreement (r = 0.435, 95 % CI [0.121, 0.689] and r = 0.422, 95 % CI [0.081, 0.0672]). Internal consistency was excellent for experts and participants (alpha = 0.96, 0.98, 0.93). AB - CONCLUSIONS: In an independent cohort, GEARS was able to differentiate between different robotic skill levels, demonstrating excellent construct validity. As a standardized assessment tool, GEARS maintained consistency and reliability for an in vivo robotic surgical task and may be applied for skills evaluation in a broad range of robotic procedures. ES - 1432-2218 IL - 0930-2794 DI - 10.1007/s00464-015-4070-8 DO - https://dx.doi.org/10.1007/s00464-015-4070-8 PT - Journal Article PT - Observational Study PT - Validation Studies ID - 25609318 [pubmed] ID - 10.1007/s00464-015-4070-8 [doi] ID - 10.1007/s00464-015-4070-8 [pii] PP - ppublish PH - 2014/09/21 [received] PH - 2015/01/08 [accepted] LG - English EP - 20150122 DP - 2015 Nov DC - 20151016 EZ - 2015/01/23 06:00 DA - 2016/06/03 06:00 DT - 2015/01/23 06:00 YR - 2015 ED - 20160602 RD - 20151016 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25609318 <89. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26765479 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Jin SJ AU - Lim HS AU - Kwon YJ AU - Park SU AU - Yi JM AU - Chin JH AU - Hwang JH AU - Kim YK FA - Jin, Seok-Joon FA - Lim, Hyeong-Seok FA - Kwon, Youn-Ju FA - Park, Se-Ung FA - Yi, Jung-Min FA - Chin, Ji-Hyun FA - Hwang, Jai-Hyun FA - Kim, Young-Kug IN - Jin, Seok-Joon. From the Department of Anesthesiology and Pain Medicine (S-JJ, S-UP, J-MY, J-HC, J-HH, Y-KK); Department of Clinical Pharmacology and Therapeutics (H-SL); and Department of Nursing, Asan Medical Center, Seoul, Republic of Korea (Y-JK). TI - Comparison of the Efficacy and Safety of a Pharmacokinetic Model-Based Dosing Scheme Versus a Conventional Fentanyl Dosing Regimen For Patient-Controlled Analgesia Immediately Following Robot-Assisted Laparoscopic Prostatectomy: A Randomized Clinical Trial. SO - Medicine. 95(2):e2542, 2016 Jan AS - Medicine (Baltimore). 95(2):e2542, 2016 Jan NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718305 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - *Analgesics, Opioid/ad [Administration & Dosage] MH - Analgesics, Opioid/ae [Adverse Effects] MH - Analgesics, Opioid/pk [Pharmacokinetics] MH - *Fentanyl/ad [Administration & Dosage] MH - Fentanyl/ae [Adverse Effects] MH - Fentanyl/pk [Pharmacokinetics] MH - Humans MH - Laparoscopy MH - Male MH - Middle Aged MH - Models, Theoretical MH - Pain Measurement MH - *Pain, Postoperative/dt [Drug Therapy] MH - *Prostatectomy MH - Robotics AB - Conventional, intravenous, patient-controlled analgesia, which is only administered by demand bolus without basal continuous infusion, is closely associated with inappropriate analgesia. Pharmacokinetic model-based dosing schemes can quantitatively describe the time course of drug effects and achieve optimal drug therapy. We compared the efficacy and safety of a conventional dosing regimen for intravenous patient-controlled analgesia that was administered by demand bolus without basal continuous infusion (group A) versus a pharmacokinetic model-based dosing scheme performed by decreasing the dosage of basal continuous infusion according to the model-based simulation used to achieve a targeted concentration (group B) following robot-assisted laparoscopic prostatectomy.In total, 70 patients were analyzed: 34 patients in group A and 36 patients in group B. The postoperative opioid requirements, pain scores assessed by the visual analog scale, and adverse events (eg, nausea, vomiting, pruritis, respiratory depression, desaturation, sedation, confusion, and urinary retention) were compared on admission to the postanesthesia care unit and at 0.5, 1, 4, 24, and 48 h after surgery between the 2 groups. All patients were kept for close observation in the postanesthesia care unit for 1 h, and then transferred to the general ward.The fentanyl requirements in the postanesthesia care unit for groups A and B were 110.0 +/- 46.4 mug and 77.5 +/- 35.3 mug, respectively. The pain scores assessed by visual analog scale at 0.5, 1, 4, and 24 h after surgery in group B were significantly lower than in group A (all P < 0.05). There were no differences in the adverse events between the 2 groups.We found that the pharmacokinetic model-based dosing scheme resulted in lower opioid requirements, lower pain scores, and no significant adverse events in the postanesthesia care unit following robot-assisted laparoscopic prostatectomy in comparison with conventional dosing regimen. RN - 0 (Analgesics, Opioid) RN - UF599785JZ (Fentanyl) ES - 1536-5964 IL - 0025-7974 DI - 00005792-201601120-00087 DO - https://dx.doi.org/10.1097/MD.0000000000002542 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 26765479 [pubmed] ID - 10.1097/MD.0000000000002542 [doi] ID - 00005792-201601120-00087 [pii] ID - PMC4718305 [pmc] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT02402621 SL - https://clinicaltrials.gov/search/term=NCT02402621 LG - English DP - 2016 Jan DC - 20160115 EZ - 2016/01/15 06:00 DA - 2016/06/01 06:00 DT - 2016/01/15 06:00 YR - 2016 ED - 20160531 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26765479 <90. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26076987 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Skarecky D AU - Gordon A AU - Babaian KN AU - Dhaliwal H AU - Morales B AU - Ahlering TE FA - Skarecky, Douglas FA - Gordon, Adam FA - Babaian, Kara N FA - Dhaliwal, Harleen FA - Morales, Blanca FA - Ahlering, Thomas E IN - Skarecky, Douglas. Department of Urology, University of California , Irvine, Medical Center, Orange, California. IN - Gordon, Adam. Department of Urology, University of California , Irvine, Medical Center, Orange, California. IN - Babaian, Kara N. Department of Urology, University of California , Irvine, Medical Center, Orange, California. IN - Dhaliwal, Harleen. Department of Urology, University of California , Irvine, Medical Center, Orange, California. IN - Morales, Blanca. Department of Urology, University of California , Irvine, Medical Center, Orange, California. IN - Ahlering, Thomas E. Department of Urology, University of California , Irvine, Medical Center, Orange, California. TI - Analysis of Improved Urinary Peak Flow Rates After Robot-Assisted Radical Prostatectomy. SO - Journal of Endourology. 29(10):1152-8, 2015 Oct AS - J Endourol. 29(10):1152-8, 2015 Oct NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - Body Weight MH - Cohort Studies MH - Humans MH - Lower Urinary Tract Symptoms/px [Psychology] MH - *Lower Urinary Tract Symptoms/su [Surgery] MH - Male MH - Middle Aged MH - Postoperative Period MH - *Prostatectomy/mt [Methods] MH - *Prostatic Diseases/su [Surgery] MH - Prostatic Neoplasms/px [Psychology] MH - *Prostatic Neoplasms/su [Surgery] MH - Quality of Life MH - *Robotic Surgical Procedures/mt [Methods] MH - Software MH - Surveys and Questionnaires MH - Time Factors MH - Urethral Obstruction/su [Surgery] MH - Urology/mt [Methods] AB - PURPOSE: Longitudinal assessment of prostatic obstruction has historically been assessed with urinary peak flow rates (PFR). In this observational study, we assess the impact of prostate removal on preoperative and postoperative PFRs after robot-assisted radical prostatectomy (RARP). AB - PATIENTS AND METHODS: A single surgeon (TA) performed RARPs between 2002 and 2007. Men underwent routine preoperative uroflowmetric testing: 550 qualified for analysis with a sufficient voided volume (VV) of 150mL preoperatively and at least once postoperatively. Continence and self-assessed American Urological Association (AUA) symptom and urinary quality of life (QoL) questionnaires were queried. Uroflows were analyzed preoperatively, short-term (3-15 mos), long-term (>2 y), and by age decades, lower urinary tract symptoms (LUTS) groups, and pathologic weight cohorts. AB - RESULTS: AUA and QoL scores improved from 8.1 and 1.6 at baseline to 4.4 and 1.0 at intermediate-term follow-up, P<0.01. Mean PFRs improved from a baseline 18.0mL/s to 28.3, 30.8, and 36.5 at 3 months, 9 months, and >5 years follow- up (all P<0.001). Postvoid residual (PVR) volumes declined from 99mL preoperatively to 24mL at >5 years (P<0.01). Likewise, all age, LUTS, and prostate weight cohorts had significant improvements in PFR and PVR and stable voided volumes throughout the study. AB - CONCLUSION: The natural history of prostatic obstruction for men 40 to 80 years typically reveals reduction of mean PFRs. We observed that removal of the prostate resulted on average with a near doubling of PFRs and decreased PVRs (>50%) by 3 months. After RARP, the average PFR was reset to 25-30mL/s, and these results were seen across all age, LUTS, and prostate weight groups; the gains remained stable 2 to 4 years after operation. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2015.0353 PT - Journal Article PT - Observational Study ID - 26076987 [pubmed] ID - 10.1089/end.2015.0353 [doi] PP - ppublish LG - English EP - 20150727 DP - 2015 Oct DC - 20151006 EZ - 2015/06/17 06:00 DA - 2016/06/01 06:00 DT - 2015/06/17 06:00 YR - 2015 ED - 20160531 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26076987 <91. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25582962 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hughes-Hallett A AU - Mayer EK AU - Marcus HJ AU - Pratt P AU - Mason S AU - Darzi AW AU - Vale JA FA - Hughes-Hallett, Archie FA - Mayer, Erik K FA - Marcus, Hani J FA - Pratt, Philip FA - Mason, Sam FA - Darzi, Ara W FA - Vale, Justin A IN - Hughes-Hallett, Archie. Department of Surgery and Cancer, Imperial College London, St Mary's Hospital Campus, London, W2 1NY, UK. a.hughes-hallett@imperial.ac.uk. IN - Mayer, Erik K. Department of Surgery and Cancer, Imperial College London, St Mary's Hospital Campus, London, W2 1NY, UK. e.mayer@imperial.ac.uk. IN - Marcus, Hani J. Department of Surgery and Cancer, Imperial College London, St Mary's Hospital Campus, London, W2 1NY, UK. IN - Marcus, Hani J. Hamlyn Centre, Institute of Global Health Innovation, Imperial College London, London, UK. IN - Pratt, Philip. Hamlyn Centre, Institute of Global Health Innovation, Imperial College London, London, UK. IN - Mason, Sam. Department of Surgery and Cancer, Imperial College London, St Mary's Hospital Campus, London, W2 1NY, UK. IN - Darzi, Ara W. Department of Surgery and Cancer, Imperial College London, St Mary's Hospital Campus, London, W2 1NY, UK. IN - Darzi, Ara W. Hamlyn Centre, Institute of Global Health Innovation, Imperial College London, London, UK. IN - Vale, Justin A. Department of Surgery and Cancer, Imperial College London, St Mary's Hospital Campus, London, W2 1NY, UK. TI - Inattention blindness in surgery. SO - Surgical Endoscopy. 29(11):3184-9, 2015 Nov AS - Surg Endosc. 29(11):3184-9, 2015 Nov NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adult MH - *Attention MH - *Burnout, Professional/et [Etiology] MH - Burnout, Professional/pp [Physiopathology] MH - Burnout, Professional/px [Psychology] MH - *Clinical Competence MH - *Cognition/ph [Physiology] MH - Female MH - Humans MH - Male MH - Pilot Projects MH - *Surgeons/px [Psychology] MH - *Surgical Procedures, Operative/st [Standards] MH - Video Recording MH - *Workload/px [Psychology] KW - Augmented reality; Cognitive load; Inattention blindness; Laparoscopic; Safety; Surgery AB - BACKGROUND: Inattention blindness (IB) can be defined as the failure to perceive an unexpected object when attention is focussed on another object or task. The principal aim of this study was to determine the effect of cognitive load and surgical image guidance on operative IB. AB - METHODS: Using a randomised control study design, participants were allocated to a high or low cognitive load group and subsequently to one of three augmented reality (AR) image guidance groups (no guidance, wireframe overlay and solid overlay). Randomised participants watched a segment of video from a robotic partial nephrectomy. Those in the high cognitive load groups were asked to keep a count of instrument movements, while those in the low cognitive load groups were only asked to watch the video. Two foreign bodies were visible within the operative scene: a swab, within the periphery of vision; and a suture, in the centre of the operative scene. Once the participants had finished watching the video, they were asked to report whether they had observed a swab or suture. AB - RESULTS: The overall level of prompted inattention blindness was 74 and 10 % for the swab and suture, respectively. Significantly higher levels of IB for the swab were seen in the high versus the low cognitive load groups, but not for the suture (8 vs. 47 %, p < 0.001 and 90 vs. 91 %, p = 1.000, for swab and suture, respectively). No significant difference was seen between image guidance groups for attention of the swab or suture (29 vs. 20 %, p = 0.520 and 22 vs. 22 %, p = 1.000, respectively). AB - CONCLUSIONS: The overall effect of IB on operative practice appeared to be significant, within the context of this study. When examining for the effects of AR image guidance and cognitive load on IB, only the latter was found to have significance. ES - 1432-2218 IL - 0930-2794 DI - 10.1007/s00464-014-4051-3 DO - https://dx.doi.org/10.1007/s00464-014-4051-3 PT - Journal Article PT - Randomized Controlled Trial ID - 25582962 [pubmed] ID - 10.1007/s00464-014-4051-3 [doi] ID - 10.1007/s00464-014-4051-3 [pii] PP - ppublish PH - 2014/08/28 [received] PH - 2014/12/16 [accepted] LG - English EP - 20150113 DP - 2015 Nov DC - 20151016 EZ - 2015/01/14 06:00 DA - 2016/06/01 06:00 DT - 2015/01/15 06:00 YR - 2015 ED - 20160531 RD - 20151016 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25582962 <92. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25552231 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Butturini G AU - Damoli I AU - Crepaz L AU - Malleo G AU - Marchegiani G AU - Daskalaki D AU - Esposito A AU - Cingarlini S AU - Salvia R AU - Bassi C FA - Butturini, Giovanni FA - Damoli, Isacco FA - Crepaz, Lorenzo FA - Malleo, Giuseppe FA - Marchegiani, Giovanni FA - Daskalaki, Despoina FA - Esposito, Alessandro FA - Cingarlini, Sara FA - Salvia, Roberto FA - Bassi, Claudio IN - Butturini, Giovanni. General Surgery B, The Pancreas Institute, Verona University Hospital Trust, Piazzale L.A. Scuro, 10, 37134, Verona, Italy. giovanni.butturini@ospedaleuniverona.it. IN - Damoli, Isacco. General Surgery B, The Pancreas Institute, Verona University Hospital Trust, Piazzale L.A. Scuro, 10, 37134, Verona, Italy. IN - Crepaz, Lorenzo. General Surgery B, The Pancreas Institute, Verona University Hospital Trust, Piazzale L.A. Scuro, 10, 37134, Verona, Italy. IN - Malleo, Giuseppe. General Surgery B, The Pancreas Institute, Verona University Hospital Trust, Piazzale L.A. Scuro, 10, 37134, Verona, Italy. IN - Marchegiani, Giovanni. General Surgery B, The Pancreas Institute, Verona University Hospital Trust, Piazzale L.A. Scuro, 10, 37134, Verona, Italy. IN - Daskalaki, Despoina. General Surgery B, The Pancreas Institute, Verona University Hospital Trust, Piazzale L.A. Scuro, 10, 37134, Verona, Italy. IN - Esposito, Alessandro. General Surgery B, The Pancreas Institute, Verona University Hospital Trust, Piazzale L.A. Scuro, 10, 37134, Verona, Italy. IN - Cingarlini, Sara. Department of Oncology, The Pancreas Institute, Verona University Hospital Trust, Piazzale L.A. Scuro, 10, 37134, Verona, Italy. IN - Salvia, Roberto. General Surgery B, The Pancreas Institute, Verona University Hospital Trust, Piazzale L.A. Scuro, 10, 37134, Verona, Italy. IN - Bassi, Claudio. General Surgery B, The Pancreas Institute, Verona University Hospital Trust, Piazzale L.A. Scuro, 10, 37134, Verona, Italy. TI - A prospective non-randomised single-center study comparing laparoscopic and robotic distal pancreatectomy. SO - Surgical Endoscopy. 29(11):3163-70, 2015 Nov AS - Surg Endosc. 29(11):3163-70, 2015 Nov NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adult MH - Aged MH - Female MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - *Pancreatectomy/mt [Methods] MH - *Pancreatic Neoplasms/su [Surgery] MH - Prospective Studies MH - *Robotics/mt [Methods] MH - Young Adult KW - Distal pancreatectomy; Laparoscopy; Pancreatic surgery; Prospective study; Robot-assisted surgery; Robotic surgery AB - BACKGROUND: Laparoscopic distal pancreatectomy (LDP) is increasing in popularity thanks to the benefits that have been recently demonstrated by many authors. The Da Vinci() Surgical System could overcome some limits of laparoscopy, helping the surgeons to perform safer and faster difficult procedures. Nowadays, prospective clinical trials comparing LDP to robotic distal pancreatectomy (RDP) are lacking. The aim of this study is to present a prospective comparison between the two techniques. AB - METHODS: Since November 2011, all patients suitable for minimally invasive distal pancreatectomy were assigned either to LDP or RDP, depending on the availability of the Da Vinci() Surgical System for our Surgical Unit. Demographics, clinical, and intra- and postoperative data, including estimated costs of the procedure, were prospectively collected. Follow-up included cross-sectional imaging ended on April 2014. AB - RESULTS: Twenty-two patients underwent RDP and 21 LDP; patients' characteristics were similar. The median operative time was longer and procedures' cost was double in RDP group. The conversion to open rate and the median length of postoperative hospital stay were 4.5 % and 7 days, respectively, in both groups. Pancreatic fistula developed in 57.1 % (12/21) and 50 % (11/22) of LDP and RDP, respectively (p = 0.870), being grade A the most frequent. Mortality was nil and an R0 resection was achieved in all Patients. The overall number of lymph nodes harvested was similar between the two groups. AB - CONCLUSIONS: Both RDP and LDP are valid techniques for the treatment of distal pancreatic tumors. The advantages of RDP are claimed by many but still under investigation. Some of these advantages are more subjective than objective, and it seems difficult to demonstrate a real superiority of one technique over the other in a standardized fashion. In our experience, laparoscopy has not been abandoned in favor of the robot: we continue to perform both approaches choosing upon single patient's characteristics. ES - 1432-2218 IL - 0930-2794 DI - 10.1007/s00464-014-4043-3 DO - https://dx.doi.org/10.1007/s00464-014-4043-3 PT - Comparative Study PT - Journal Article ID - 25552231 [pubmed] ID - 10.1007/s00464-014-4043-3 [doi] ID - 10.1007/s00464-014-4043-3 [pii] PP - ppublish PH - 2014/08/05 [received] PH - 2014/12/11 [accepted] LG - English EP - 20150101 DP - 2015 Nov DC - 20151016 EZ - 2015/01/02 06:00 DA - 2016/06/01 06:00 DT - 2015/01/02 06:00 YR - 2015 ED - 20160531 RD - 20151016 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25552231 <93. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26765479 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Jin SJ AU - Lim HS AU - Kwon YJ AU - Park SU AU - Yi JM AU - Chin JH AU - Hwang JH AU - Kim YK FA - Jin, Seok-Joon FA - Lim, Hyeong-Seok FA - Kwon, Youn-Ju FA - Park, Se-Ung FA - Yi, Jung-Min FA - Chin, Ji-Hyun FA - Hwang, Jai-Hyun FA - Kim, Young-Kug IN - Jin, Seok-Joon. From the Department of Anesthesiology and Pain Medicine (S-JJ, S-UP, J-MY, J-HC, J-HH, Y-KK); Department of Clinical Pharmacology and Therapeutics (H-SL); and Department of Nursing, Asan Medical Center, Seoul, Republic of Korea (Y-JK). TI - Comparison of the Efficacy and Safety of a Pharmacokinetic Model-Based Dosing Scheme Versus a Conventional Fentanyl Dosing Regimen For Patient-Controlled Analgesia Immediately Following Robot-Assisted Laparoscopic Prostatectomy: A Randomized Clinical Trial. SO - Medicine. 95(2):e2542, 2016 Jan AS - Medicine (Baltimore). 95(2):e2542, 2016 Jan NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718305 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - *Analgesics, Opioid/ad [Administration & Dosage] MH - Analgesics, Opioid/ae [Adverse Effects] MH - Analgesics, Opioid/pk [Pharmacokinetics] MH - *Fentanyl/ad [Administration & Dosage] MH - Fentanyl/ae [Adverse Effects] MH - Fentanyl/pk [Pharmacokinetics] MH - Humans MH - Laparoscopy MH - Male MH - Middle Aged MH - Models, Theoretical MH - Pain Measurement MH - *Pain, Postoperative/dt [Drug Therapy] MH - *Prostatectomy MH - Robotics AB - Conventional, intravenous, patient-controlled analgesia, which is only administered by demand bolus without basal continuous infusion, is closely associated with inappropriate analgesia. Pharmacokinetic model-based dosing schemes can quantitatively describe the time course of drug effects and achieve optimal drug therapy. We compared the efficacy and safety of a conventional dosing regimen for intravenous patient-controlled analgesia that was administered by demand bolus without basal continuous infusion (group A) versus a pharmacokinetic model-based dosing scheme performed by decreasing the dosage of basal continuous infusion according to the model-based simulation used to achieve a targeted concentration (group B) following robot-assisted laparoscopic prostatectomy.In total, 70 patients were analyzed: 34 patients in group A and 36 patients in group B. The postoperative opioid requirements, pain scores assessed by the visual analog scale, and adverse events (eg, nausea, vomiting, pruritis, respiratory depression, desaturation, sedation, confusion, and urinary retention) were compared on admission to the postanesthesia care unit and at 0.5, 1, 4, 24, and 48 h after surgery between the 2 groups. All patients were kept for close observation in the postanesthesia care unit for 1 h, and then transferred to the general ward.The fentanyl requirements in the postanesthesia care unit for groups A and B were 110.0 +/- 46.4 mug and 77.5 +/- 35.3 mug, respectively. The pain scores assessed by visual analog scale at 0.5, 1, 4, and 24 h after surgery in group B were significantly lower than in group A (all P < 0.05). There were no differences in the adverse events between the 2 groups.We found that the pharmacokinetic model-based dosing scheme resulted in lower opioid requirements, lower pain scores, and no significant adverse events in the postanesthesia care unit following robot-assisted laparoscopic prostatectomy in comparison with conventional dosing regimen. RN - 0 (Analgesics, Opioid) RN - UF599785JZ (Fentanyl) ES - 1536-5964 IL - 0025-7974 DI - 00005792-201601120-00087 DO - https://dx.doi.org/10.1097/MD.0000000000002542 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 26765479 [pubmed] ID - 10.1097/MD.0000000000002542 [doi] ID - 00005792-201601120-00087 [pii] ID - PMC4718305 [pmc] PP - ppublish LG - English DP - 2016 Jan DC - 20160115 EZ - 2016/01/15 06:00 DA - 2016/06/01 06:00 DT - 2016/01/15 06:00 YR - 2016 ED - 20160531 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=26765479 <94. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26317357 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Yoo YC AU - Kim NY AU - Shin S AU - Choi YD AU - Hong JH AU - Kim CY AU - Park H AU - Bai SJ FA - Yoo, Young-Chul FA - Kim, Na Young FA - Shin, Seokyung FA - Choi, Young Deuk FA - Hong, Jung Hwa FA - Kim, Chan Yun FA - Park, HeeJoon FA - Bai, Sun-Joon IN - Yoo, Young-Chul. Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. IN - Kim, Na Young. Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. IN - Shin, Seokyung. Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. IN - Choi, Young Deuk. Department of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. IN - Hong, Jung Hwa. Biostatistics Collaboration Units, Department of Research Affairs, Yonsei University College of Medicine, Seoul, Republic of Korea. IN - Kim, Chan Yun. Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Republic of Korea. IN - Park, HeeJoon. Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. IN - Bai, Sun-Joon. Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. TI - The Intraocular Pressure under Deep versus Moderate Neuromuscular Blockade during Low-Pressure Robot Assisted Laparoscopic Radical Prostatectomy in a Randomized Trial. SO - PLoS ONE [Electronic Resource]. 10(8):e0135412, 2015 AS - PLoS ONE. 10(8):e0135412, 2015 NJ - PloS one PI - Journal available in: Electronic-eCollection PI - Citation processed from: Internet JC - 101285081 IO - PLoS ONE PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552736 SB - Index Medicus CP - United States MH - Aged MH - Blood Pressure MH - Humans MH - *Intraocular Pressure MH - Laparoscopy/mt [Methods] MH - *Laparoscopy MH - Male MH - Middle Aged MH - Neuromuscular Blockade/mt [Methods] MH - *Neuromuscular Blockade MH - Prostatectomy/mt [Methods] MH - *Prostatectomy MH - Risk Factors MH - Robotic Surgical Procedures/mt [Methods] MH - *Robotic Surgical Procedures MH - Treatment Outcome AB - BACKGROUND: This study aimed to determine whether continuous deep neuromuscular blockade (NMB) improves the surgical conditions and facilitates robotic-assisted laparoscopic radical prostatectomy (RALRP) under low intra-abdominal pressure (IAP) to attenuate the increase in intraocular pressure (IOP) during CO2 pneumoperitoneum in the steep Trendelenburg (ST) position. AB - METHODS: Sixty-seven patients undergoing RALRP were randomly assigned to a moderate NMB group (Group M), including patients who received atracurium infusion until the end of the ST position, maintaining a train of four count of 1-2; and the deep NMB group (Group D), including patients who received rocuronium infusion, maintaining a post-tetanic count of 1-2. IOP was measured in all patients at nine separate time points. All RALRPs were performed by one surgeon, who rated the overall and worst surgical conditions at the end of the ST position. AB - RESULTS: The highest IOP value was observed at T4 (60 min after the ST position) in both Group M (23.3 +/- 2.7 mmHg) and Group D (19.8 +/- 2.1 mmHg). RALRP was accomplished at an IAP of 8 mmHg in 88% Group D patients and 25% Group M patients. The overall surgical condition grade was 4.0 (3.0-5.0) in Group D and 3.0 (2.0-5.0) in Group M (P < 0.001). AB - CONCLUSION: The current study demonstrated that continuous deep NMB may improve surgical conditions and facilitate RALRP at a low IAP, resulting in significant attenuation of the increase on IOP. Moreover, low-pressure pneumoperitoneum, facilitated by deep NMB still provided acceptable surgical conditions. AB - TRIAL REGISTRATION: ClinicalTrials.gov NCT02109133. ES - 1932-6203 IL - 1932-6203 DI - PONE-D-15-16344 DO - https://dx.doi.org/10.1371/journal.pone.0135412 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 26317357 [pubmed] ID - 10.1371/journal.pone.0135412 [doi] ID - PONE-D-15-16344 [pii] ID - PMC4552736 [pmc] PP - epublish PH - 2015/04/27 [received] PH - 2015/07/20 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT02109133 SA - ClinicalTrials.gov/NCT02109133 SL - https://clinicaltrials.gov/search/term=NCT02109133 SL - https://clinicaltrials.gov/search/term=NCT02109133 LG - English EP - 20150828 DP - 2015 DC - 20150831 EZ - 2015/08/29 06:00 DA - 2016/05/25 06:00 DT - 2015/09/01 06:00 YR - 2015 ED - 20160524 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26317357 <95. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26317357 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Yoo YC AU - Kim NY AU - Shin S AU - Choi YD AU - Hong JH AU - Kim CY AU - Park H AU - Bai SJ FA - Yoo, Young-Chul FA - Kim, Na Young FA - Shin, Seokyung FA - Choi, Young Deuk FA - Hong, Jung Hwa FA - Kim, Chan Yun FA - Park, HeeJoon FA - Bai, Sun-Joon IN - Yoo, Young-Chul. Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. IN - Kim, Na Young. Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. IN - Shin, Seokyung. Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. IN - Choi, Young Deuk. Department of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. IN - Hong, Jung Hwa. Biostatistics Collaboration Units, Department of Research Affairs, Yonsei University College of Medicine, Seoul, Republic of Korea. IN - Kim, Chan Yun. Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Republic of Korea. IN - Park, HeeJoon. Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. IN - Bai, Sun-Joon. Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. TI - The Intraocular Pressure under Deep versus Moderate Neuromuscular Blockade during Low-Pressure Robot Assisted Laparoscopic Radical Prostatectomy in a Randomized Trial. SO - PLoS ONE [Electronic Resource]. 10(8):e0135412, 2015 AS - PLoS ONE. 10(8):e0135412, 2015 NJ - PloS one PI - Journal available in: Electronic-eCollection PI - Citation processed from: Internet JC - 101285081 IO - PLoS ONE PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552736 SB - Index Medicus CP - United States MH - Aged MH - Blood Pressure MH - Humans MH - *Intraocular Pressure MH - Laparoscopy/mt [Methods] MH - *Laparoscopy MH - Male MH - Middle Aged MH - Neuromuscular Blockade/mt [Methods] MH - *Neuromuscular Blockade MH - Prostatectomy/mt [Methods] MH - *Prostatectomy MH - Risk Factors MH - Robotic Surgical Procedures/mt [Methods] MH - *Robotic Surgical Procedures MH - Treatment Outcome AB - BACKGROUND: This study aimed to determine whether continuous deep neuromuscular blockade (NMB) improves the surgical conditions and facilitates robotic-assisted laparoscopic radical prostatectomy (RALRP) under low intra-abdominal pressure (IAP) to attenuate the increase in intraocular pressure (IOP) during CO2 pneumoperitoneum in the steep Trendelenburg (ST) position. AB - METHODS: Sixty-seven patients undergoing RALRP were randomly assigned to a moderate NMB group (Group M), including patients who received atracurium infusion until the end of the ST position, maintaining a train of four count of 1-2; and the deep NMB group (Group D), including patients who received rocuronium infusion, maintaining a post-tetanic count of 1-2. IOP was measured in all patients at nine separate time points. All RALRPs were performed by one surgeon, who rated the overall and worst surgical conditions at the end of the ST position. AB - RESULTS: The highest IOP value was observed at T4 (60 min after the ST position) in both Group M (23.3 +/- 2.7 mmHg) and Group D (19.8 +/- 2.1 mmHg). RALRP was accomplished at an IAP of 8 mmHg in 88% Group D patients and 25% Group M patients. The overall surgical condition grade was 4.0 (3.0-5.0) in Group D and 3.0 (2.0-5.0) in Group M (P < 0.001). AB - CONCLUSION: The current study demonstrated that continuous deep NMB may improve surgical conditions and facilitate RALRP at a low IAP, resulting in significant attenuation of the increase on IOP. Moreover, low-pressure pneumoperitoneum, facilitated by deep NMB still provided acceptable surgical conditions. AB - TRIAL REGISTRATION: ClinicalTrials.gov NCT02109133. ES - 1932-6203 IL - 1932-6203 DI - PONE-D-15-16344 DO - https://dx.doi.org/10.1371/journal.pone.0135412 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 26317357 [pubmed] ID - 10.1371/journal.pone.0135412 [doi] ID - PONE-D-15-16344 [pii] ID - PMC4552736 [pmc] PP - epublish PH - 2015/04/27 [received] PH - 2015/07/20 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT02109133 SL - https://clinicaltrials.gov/search/term=NCT02109133 LG - English EP - 20150828 DP - 2015 DC - 20150831 EZ - 2015/08/29 06:00 DA - 2016/05/25 06:00 DT - 2015/09/01 06:00 YR - 2015 ED - 20160524 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=26317357 <96. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25869025 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kim MS AU - Kim NY AU - Lee KY AU - Choi YD AU - Hong JH AU - Bai SJ FA - Kim, Min-Soo FA - Kim, Na Young FA - Lee, Ki-Young FA - Choi, Young Deuk FA - Hong, Jung Hwa FA - Bai, Sun-Joon IN - Kim, Min-Soo. Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Korea. TI - The impact of two different inspiratory to expiratory ratios (1:1 and 1:2) on respiratory mechanics and oxygenation during volume-controlled ventilation in robot-assisted laparoscopic radical prostatectomy: a randomized controlled trial. SO - Canadian Journal of Anaesthesia. 62(9):979-87, 2015 Sep AS - Can J Anaesth. 62(9):979-87, 2015 Sep NJ - Canadian journal of anaesthesia = Journal canadien d'anesthesie PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - c8l, 8701709 IO - Can J Anaesth SB - Index Medicus CP - United States MH - Aged MH - Blood Gas Analysis MH - Double-Blind Method MH - Head-Down Tilt MH - Humans MH - Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - *Oxygen/bl [Blood] MH - Pneumoperitoneum, Artificial/mt [Methods] MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Respiration, Artificial/mt [Methods] MH - *Respiratory Mechanics/ph [Physiology] MH - Robotics/mt [Methods] MH - Time Factors AB - BACKGROUND: Volume-controlled ventilation with a prolonged inspiratory to expiratory ratio (I:E ratio) has been used to optimize gas exchange and respiratory mechanics in various surgical settings. We hypothesized that, when compared with an I:E ratio of 1:2, a prolonged I:E ratio of 1:1 would improve respiratory mechanics without reducing cardiac output (CO) during pneumoperitoneum and steep Trendelenburg positioning, both of which can impair respiratory function in robot-assisted laparoscopic radical prostatectomy. Furthermore, we evaluated its effect on oxygenation during robot-assisted laparoscopic radical prostatectomy. AB - METHODS: Eighty patients undergoing robot-assisted laparoscopic radical prostatectomy were randomly allocated to receive an I:E ratio of either 1:1 (group 1:1) or 1:2 (group 1:2). The primary endpoint, peak airway pressure (Ppeak), as well as hemodynamic data, including cardiac output (CO) and arterial oxygen tension (PaO2), were compared between groups at four time points: ten minutes after anesthesia induction (T1), 30 and 60 min after pneumoperitoneum with steep Trendelenburg positioning (T2 and T3), and ten minutes after supine positioning (T4). Overall comparisons were made between groups using linear mixed model analysis with post hoc testing of individual time points adjusted using a Bonferroni correction. AB - RESULTS: Linear mixed model analysis showed a significant overall difference in Ppeak between the two groups (P < 0.001). Post hoc analysis showed a significantly lower mean (SD) Ppeak in group 1:1 than in group 1:2 at T2 [28.4 (4.0) cm H2O vs 32.8 (5.2) cm H2O, respectively; mean difference, 4.3 cm H2O; 95% confidence interval (CI), 2.3 to 6.4; P < 0.001] and T3 [27.8 (3.9) cm H2O vs 32.6 (5.0) cm H2O, respectively; mean difference, 4.7 cm H2O; 95% CI, 2.7 to 6.7; P < 0.001]. The CO assessed over these time points was comparable in both groups (P = 0.784). In addition, there were no significant differences in PaO2 between the two groups (P = 0.521). AB - CONCLUSIONS: Compared with an I:E ratio of 1:2, a ratio of 1:1 lowered Ppeak without reducing CO during pneumoperitoneum and steep Trendelenburg positioning. Nevertheless, our results did not support its use solely for improving oxygenation. This trial was registered at http://clinicaltrials.gov/ (NCT01892449). RN - S88TT14065 (Oxygen) ES - 1496-8975 IL - 0832-610X DI - 10.1007/s12630-015-0383-2 DO - https://dx.doi.org/10.1007/s12630-015-0383-2 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 25869025 [pubmed] ID - 10.1007/s12630-015-0383-2 [doi] ID - 10.1007/s12630-015-0383-2 [pii] PP - ppublish PH - 2014/12/01 [received] PH - 2015/04/01 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01892449 SL - https://clinicaltrials.gov/search/term=NCT01892449 LG - English EP - 20150414 DP - 2015 Sep DC - 20150815 EZ - 2015/04/15 06:00 DA - 2016/05/20 06:00 DT - 2015/04/15 06:00 YR - 2015 ED - 20160519 RD - 20150815 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25869025 <97. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26176878 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Vrooman B AU - Kapural L AU - Sarwar S AU - Mascha EJ AU - Mihaljevic T AU - Gillinov M AU - Qavi S AU - Sessler DI FA - Vrooman, Bruce FA - Kapural, Leonardo FA - Sarwar, Sheryar FA - Mascha, Edward J FA - Mihaljevic, Tomislav FA - Gillinov, Marc FA - Qavi, Shahbaz FA - Sessler, Daniel I IN - Vrooman, Bruce. Department of Pain Management, Cleveland Clinic, Cleveland, Ohio, USA. IN - Kapural, Leonardo. Carolinas Pain Institute at Brookstown, Wake Forest University, School of Medicine, Winston-Salem, North Carolina, USA. IN - Sarwar, Sheryar. Department of Family Medicine, University Hospitals of Cleveland, Cleveland, Ohio, USA. IN - Mascha, Edward J. Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA. IN - Mascha, Edward J. Department of Outcomes Research, Cleveland Clinic, Cleveland, Ohio, USA. IN - Mihaljevic, Tomislav. Department of Cardiothoracic Surgery, Cleveland Clinic, Cleveland, Ohio, USA. IN - Gillinov, Marc. Department of Cardiothoracic Surgery, Cleveland Clinic, Cleveland, Ohio, USA. IN - Qavi, Shahbaz. Resident, Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio, USA. IN - Sessler, Daniel I. Department of Outcomes Research, Cleveland Clinic, Cleveland, Ohio, USA. TI - Lidocaine 5% Patch for Treatment of Acute Pain After Robotic Cardiac Surgery and Prevention of Persistent Incisional Pain: A Randomized, Placebo-Controlled, Double-Blind Trial. SO - Pain Medicine. 16(8):1610-21, 2015 Aug AS - PAIN MED. 16(8):1610-21, 2015 Aug NJ - Pain medicine (Malden, Mass.) PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 100894201 IO - Pain Med SB - Index Medicus CP - England MH - Acute Pain MH - Aged MH - Analgesia, Patient-Controlled MH - Analgesics, Opioid/tu [Therapeutic Use] MH - Anesthetics, Local/ad [Administration & Dosage] MH - *Anesthetics, Local/tu [Therapeutic Use] MH - *Cardiac Surgical Procedures/ae [Adverse Effects] MH - Disability Evaluation MH - Double-Blind Method MH - Female MH - Heart Valves/su [Surgery] MH - Humans MH - Lidocaine/ad [Administration & Dosage] MH - *Lidocaine/tu [Therapeutic Use] MH - Male MH - Middle Aged MH - Pain Measurement MH - *Pain, Postoperative/pc [Prevention & Control] MH - Patient Satisfaction MH - *Robotics MH - Transdermal Patch KW - Anesthesia; Lidocaine 5% Patch; Post-Thoracotomy Pain AB - OBJECTIVES: To test the hypotheses that lidocaine 5% patches decrease the severity of acute pain and incidence of persistent incisional pain after robotic cardiac valve surgery. AB - DESIGN: A randomized, placebo-controlled, double-blind trial. AB - SETTING: Tertiary care academic medical center. AB - SUBJECTS: Patients having robotic cardiac valve surgery. AB - METHODS: Patients having robotic cardiac valve surgery were randomly assigned to 5% lidocaine patches or identical-appearing placebo patches. Patches were applied around each incision 12 hours/day until pain resolved, or for 6 months. Supplemental opioid was provided by patient-controlled analgesia or orally. Pain was initially evaluated with a Visual Analog Scale, and subsequently by telephone with a Verbal Response Scale and the Pain Disability Index (our primary outcome) after 1 week, 1 month, 3 months, and 6 months. Global Perceived Effect, a measure of patient satisfaction, was simultaneously recorded. Repeated-measures analysis of variance and generalized estimating equations were our primary statistical tools. AB - RESULTS: Acute pain scores and opioid use were low, as was the incidence of persistent pain. Lidocaine 5% patches did not influence any measure of acute or persistent incisional pain. Estimated difference (95% CI) in mean Pain Disability Index for Lidocaine patch minus placebo was -2.5 (95% CI -7.1, 2.1), P=0.28. AB - CONCLUSIONS: Lidocaine 5% patches did not reduce acute or persistent pain in patients having robotic thoracic surgery, though pain scores were low in both treatment groups. Clinicians should choose alternative analgesic approaches in these patients. AB - Copyright Wiley Periodicals, Inc. RN - 0 (Analgesics, Opioid) RN - 0 (Anesthetics, Local) RN - 0 (Lidoderm) RN - 98PI200987 (Lidocaine) ES - 1526-4637 IL - 1526-2375 DO - https://dx.doi.org/10.1111/pme.12721 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 26176878 [pubmed] ID - 10.1111/pme.12721 [doi] PP - ppublish LG - English EP - 20150714 DP - 2015 Aug DC - 20150819 EZ - 2015/07/16 06:00 DA - 2016/05/18 06:00 DT - 2015/07/16 06:00 YR - 2015 ED - 20160517 RD - 20150819 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26176878 <98. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26262764 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Seo H AU - Bang JY AU - Oh J AU - Choi WJ AU - Song JG AU - Hwang GS FA - Seo, Hyungseok FA - Bang, Ji-yeon FA - Oh, Jimi FA - Choi, Woo-jong FA - Song, Jun-gol FA - Hwang, Gyu-sam IN - Seo, Hyungseok. 1 Department of Anesthesia and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine , Seoul, Korea. IN - Bang, Ji-yeon. 2 Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine , Seoul, Korea. IN - Oh, Jimi. 2 Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine , Seoul, Korea. IN - Choi, Woo-jong. 2 Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine , Seoul, Korea. IN - Song, Jun-gol. 2 Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine , Seoul, Korea. IN - Hwang, Gyu-sam. 2 Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine , Seoul, Korea. TI - Effect of Tracheal Cuff Shape on Intracuff Pressure Change During Robot-Assisted Laparoscopic Surgery: The Tapered-Shaped Cuff Tube Versus the Cylindrical-Shaped Cuff Tube. SO - Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A. 25(9):724-9, 2015 Sep AS - J Laparoendosc Adv Surg Tech A. 25(9):724-9, 2015 Sep NJ - Journal of laparoendoscopic & advanced surgical techniques. Part A PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 9706293, c0d IO - J Laparoendosc Adv Surg Tech A SB - Index Medicus CP - United States MH - *Cholecystectomy/mt [Methods] MH - Female MH - Humans MH - *Intubation, Intratracheal/is [Instrumentation] MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - Preoperative Care MH - Pressure MH - *Robotics/mt [Methods] MH - Treatment Outcome AB - BACKGROUND: Although the cuff of tracheal tubes can reduce airflow leakage and prevent aspiration, excessive intracuff pressure can cause tracheal mucosal injury. Robot-assisted laparoscopic surgery (RALS) can increase intracuff pressure by the Trendelenburg position and pneumoperitoneum. The aim of our current study was to investigate the effect of tracheal cuff shape on the intracuff pressure increase by comparing two different-shaped cuffs during RALS. AB - MATERIALS AND METHODS: Ninety-eight patients undergoing RALS were allocated randomly into two groups (tapered-shaped cuff [TSC] and cylindrical-shaped cuff [CSC] groups). The intracuff pressure was measured at nine specific time points: after intubation, immediately after surgical preparation (Trendelenburg position with CO2 insufflation), at 5, 10, 15, 30, 60, and 90 minutes after surgical preparation, and at the end of surgery. Postintubation airway symptoms were measured by assessing sore throat, hoarseness, and excessive cough 1 hour after postanesthesia care unit admission. AB - RESULTS: Intracuff pressure significantly increased during surgery in both groups. The trend of intracuff pressure change decreased in the TSC group compared with the CSC group, although no statistically significant changes were found (P=.450). Also, there were no statistically significant differences in the postintubation airway symptom between the two groups. AB - CONCLUSIONS: The TSC tube has a tendency to decrease intracuff pressure change compared with the CSC tube during RALS. However, neither of them was beneficial in preventing intraoperative intracuff pressure increase during RALS. ES - 1557-9034 IL - 1092-6429 DO - https://dx.doi.org/10.1089/lap.2015.0152 PT - Journal Article PT - Randomized Controlled Trial ID - 26262764 [pubmed] ID - 10.1089/lap.2015.0152 [doi] PP - ppublish LG - English EP - 20150811 DP - 2015 Sep DC - 20150917 EZ - 2015/08/12 06:00 DA - 2016/05/11 06:00 DT - 2015/08/12 06:00 YR - 2015 ED - 20160510 RD - 20150917 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26262764 <99. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25687748 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Arujuna A AU - Karim R AU - Zarinabad N AU - Gill J AU - Rhode K AU - Schaeffter T AU - Wright M AU - Rinaldi CA AU - Cooklin M AU - Razavi R AU - O'Neill MD AU - Gill JS FA - Arujuna, Aruna FA - Karim, Rashed FA - Zarinabad, Niloufar FA - Gill, Jaspal FA - Rhode, Kawal FA - Schaeffter, Tobias FA - Wright, Matthew FA - Rinaldi, C Aldo FA - Cooklin, Michael FA - Razavi, Reza FA - O'Neill, Mark D FA - Gill, Jaswinder S IN - Arujuna, Aruna. Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, London SE1 7EH, UK Department of Cardiology, Guy's and St. Thomas' NHS Foundation Trust, London, UK aruna.arujuna@kcl.ac.uk. IN - Karim, Rashed. Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, London SE1 7EH, UK. IN - Zarinabad, Niloufar. Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, London SE1 7EH, UK. IN - Gill, Jaspal. Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, London SE1 7EH, UK. IN - Rhode, Kawal. Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, London SE1 7EH, UK. IN - Schaeffter, Tobias. Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, London SE1 7EH, UK. IN - Wright, Matthew. Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, London SE1 7EH, UK Department of Cardiology, Guy's and St. Thomas' NHS Foundation Trust, London, UK. IN - Rinaldi, C Aldo. Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, London SE1 7EH, UK Department of Cardiology, Guy's and St. Thomas' NHS Foundation Trust, London, UK. IN - Cooklin, Michael. Department of Cardiology, Guy's and St. Thomas' NHS Foundation Trust, London, UK. IN - Razavi, Reza. Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, London SE1 7EH, UK Department of Cardiology, Guy's and St. Thomas' NHS Foundation Trust, London, UK. IN - O'Neill, Mark D. Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, London SE1 7EH, UK Department of Cardiology, Guy's and St. Thomas' NHS Foundation Trust, London, UK. IN - Gill, Jaswinder S. Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, London SE1 7EH, UK Department of Cardiology, Guy's and St. Thomas' NHS Foundation Trust, London, UK. TI - A randomized prospective mechanistic cardiac magnetic resonance study correlating catheter stability, late gadolinium enhancement and 3 year clinical outcomes in robotically assisted vs. standard catheter ablation. SO - Europace. 17(8):1241-50, 2015 Aug AS - Europace. 17(8):1241-50, 2015 Aug NJ - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - dxd, 100883649 IO - Europace PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535555 SB - Index Medicus CP - England MH - *Atrial Fibrillation/pa [Pathology] MH - *Atrial Fibrillation/su [Surgery] MH - *Catheter Ablation/mt [Methods] MH - Contrast Media MH - Female MH - Gadolinium MH - Humans MH - Longitudinal Studies MH - *Magnetic Resonance Imaging, Cine/mt [Methods] MH - Male MH - Middle Aged MH - Prospective Studies MH - Reproducibility of Results MH - *Robotic Surgical Procedures/mt [Methods] MH - Sensitivity and Specificity MH - Statistics as Topic MH - *Surgery, Computer-Assisted/mt [Methods] MH - Treatment Outcome KW - Atrial fibrillation; Cardiac magnetic resonance imaging; Catheter ablation; Long-term follow-up; Pulmonary vein isolation; Robotic-assisted AB - AIMS: To prospectively compare cardiac magnetic resonance late gadolinium enhancement (LGE) findings created by standard vs. robotically assisted catheter ablation lesions and correlate these with clinical outcomes. AB - METHODS AND RESULTS: Forty paroxysmal atrial fibrillation patients (mean age 54 +/- 13.8 years) undergoing first left atrial ablation were randomized to either robotic-assisted navigation (Hansen Sensei() X) or standard navigation. Pre-procedural, acute (24 h post-procedure) and late (beyond 3 months) scans were performed with LGE and T2W imaging sequences and percentage circumferential enhancement around the pulmonary vein (PV) antra were quantified. Baseline pre-procedural enhancements were similar in both groups. On acute imaging, mean % encirclements by LGE and T2W signal were 72% and 80% in the robotic group vs. 60% (P = 0.002) and 76%(P = 0.45) for standard ablation. On late imaging, the T2W signal resolved to baseline in both groups. Late gadolinium enhancement remained the predominant signal with 56% encirclement in the robotic group vs. 45% in the standard group (P = 0.04). At 6 months follow-up, arrhythmia-free patients had an almost similar mean LGE encirclement (robotic 64%, standard 60%, P = 0.45) but in recurrences, LGE was higher in the robotic group (43% vs. 30%, P = 0.001). At mean 3 years follow-up, 1.3 procedures were performed in the robotic group compared with 1.9 (P < 0.001) in the standard to achieve a success rate of 80% vs. 75%. AB - CONCLUSION: Robotically assisted ablation results in greater LGE around the PV antrum. Effective lesions created through improved catheter stability and contact force during initial treatment may have a role in reducing subsequent re-do procedures. AB - Copyright © The Author 2015. Published by Oxford University Press on behalf of the European Society of Cardiology. RN - 0 (Contrast Media) RN - AU0V1LM3JT (Gadolinium) ES - 1532-2092 IL - 1099-5129 DI - euu364 DO - https://dx.doi.org/10.1093/europace/euu364 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 25687748 [pubmed] ID - euu364 [pii] ID - 10.1093/europace/euu364 [doi] ID - PMC4535555 [pmc] PP - ppublish PH - 2014/08/18 [received] PH - 2014/11/17 [accepted] GI - No: WT 088641/Z/09/Z Organization: *Wellcome Trust* Country: United Kingdom LG - English EP - 20150216 DP - 2015 Aug DC - 20150814 EZ - 2015/02/18 06:00 DA - 2016/05/11 06:00 DT - 2015/02/18 06:00 YR - 2015 ED - 20160510 RD - 20161019 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25687748 <100. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26541978 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Herling SF AU - Moller AM AU - Palle C AU - Thomsen T FA - Herling, Suzanne F FA - Moller, Ann M FA - Palle, Connie FA - Thomsen, Thordis IN - Herling, Suzanne F. Research Unit in the Department of Anesthesiology, Copenhagen University Hospital, Herlev, Herlev Ringvej 75, DK-2730, Denmark. Electronic address: Suzanne.herling@gmail.com. IN - Moller, Ann M. Research Unit in the Department of Anesthesiology, Copenhagen University Hospital, Herlev, Herlev Ringvej 75, DK-2730, Denmark. IN - Palle, Connie. Department of Gynecology, Copenhagen University Hospital, Herlev, Herlev Ringvej 75, DK-2730, Denmark. IN - Thomsen, Thordis. Abdominal Centre, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100, Denmark. TI - Health-related quality of life after robotic-assisted laparoscopic hysterectomy for women with endometrial cancer--A prospective cohort study. SO - Gynecologic Oncology. 140(1):107-13, 2016 Jan AS - Gynecol Oncol. 140(1):107-13, 2016 Jan NJ - Gynecologic oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - fxc, 0365304 IO - Gynecol. Oncol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - Cohort Studies MH - *Endometrial Neoplasms/su [Surgery] MH - Female MH - Humans MH - Hysterectomy/ae [Adverse Effects] MH - Hysterectomy/mt [Methods] MH - *Hysterectomy/st [Standards] MH - Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/mt [Methods] MH - *Laparoscopy/st [Standards] MH - Middle Aged MH - Patient Satisfaction MH - Prospective Studies MH - Quality of Life MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - Robotic Surgical Procedures/mt [Methods] MH - *Robotic Surgical Procedures/st [Standards] MH - Treatment Outcome KW - Endometrial neoplasms; Hysterectomy; Patient-reported outcome measures; Quality of life; Robotics AB - OBJECTIVE: The aim of this prospective cohort study using patient-reported outcome measures (PROMs) was to detect short term changes in functioning, symptoms and health-related quality of life (HRQoL) after robotic-assisted laparoscopic hysterectomy (RALH) for endometrial cancer or atypical complex hyperplasia. AB - METHODS/MATERIALS: A total of 139 women answered the EORTC C-30, EN-24 and EQ-5D-3L preoperatively (baseline) by face to face interview and again 1 week, 5 weeks and 4 months postoperatively by telephone interview. The women furthermore reported their level of activity compared to their habitual level in a diary during the first 5 weeks after surgery. AB - RESULTS: We found a clinically relevant decrease in HRQoL after 1 week. At 5 weeks postoperatively, HRQoL was again at the preoperative level. Fatigue, pain, constipation, gastrointestinal symptoms, and appetite were all negatively affected 1 week postoperatively, but back to baseline level at 5 weeks. Ability to perform work or hobbies and change of taste were still affected at 5 weeks. AB - CONCLUSIONS: HRQoL and postoperative symptoms were overall back to the preoperative level 5 weeks after RALH. These findings indicate fatigue, pain, constipation, gastrointestinal symptoms, appetite, ability to perform work and hobbies, change of taste and sexually related problems should be addressed in future research and in the pre- and postoperative care for women undergoing RALH. AB - Copyright © 2015 Elsevier Inc. All rights reserved. ES - 1095-6859 IL - 0090-8258 DI - S0090-8258(15)30171-2 DO - https://dx.doi.org/10.1016/j.ygyno.2015.10.024 PT - Journal Article ID - 26541978 [pubmed] ID - S0090-8258(15)30171-2 [pii] ID - 10.1016/j.ygyno.2015.10.024 [doi] PP - ppublish PH - 2015/09/09 [received] PH - 2015/10/30 [revised] PH - 2015/10/31 [accepted] LG - English EP - 20151102 DP - 2016 Jan DC - 20160103 EZ - 2015/11/07 06:00 DA - 2016/04/29 06:00 DT - 2015/11/07 06:00 YR - 2016 ED - 20160428 RD - 20160103 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26541978 <101. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26496344 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Jung MJ AU - Lee SY AU - Lee SH AU - Kang CM AU - Lee WJ FA - Jung, Myung Jae FA - Lee, So Young FA - Lee, Sung Hwan FA - Kang, Chang Moo FA - Lee, Woo Jung IN - Jung, Myung Jae. From the Department of Hepatobiliary and Pancreatic Surgery, Yonsei University College of Medicine (SYL, SHL, CMK, WJL); Department of Critical Care and Trauma Surgery, Yonsei University College of Medicine (MJJ); and Pancreaticobiliary Cancer Clinic, Institute of Gastroenterology, Yonsei University Severance Hospital, Seoul, Korea (SYL, SHL, CMK, WJL). TI - Single-Site Robotic Cholecystectomy: Reverse-Port Technique. SO - Medicine. 94(42):e1871, 2015 Oct AS - Medicine (Baltimore). 94(42):e1871, 2015 Oct NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620793 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adolescent MH - Adult MH - *Cholecystectomy, Laparoscopic/is [Instrumentation] MH - *Cholecystectomy, Laparoscopic/mt [Methods] MH - Female MH - Humans MH - Male MH - Middle Aged MH - Retrospective Studies MH - Robotic Surgical Procedures/is [Instrumentation] MH - *Robotic Surgical Procedures MH - Young Adult AB - This study aims to introduce an alternative technique for effective single-site robotic cholecystectomy (SSRC) using a reverse port.Proper exposure of Calot's triangle is critical for safe laparoscopic cholecystectomy. Current robotic surgical systems are useful for single-site cholecystectomy. However, in exposing Calot's triangle, the gallbladder is usually retracted in a medial and upward direction, resulting in a narrow triangle. This intraoperative view is a major obstacle to safe laparoscopic cholecystectomy.From October 2013 to October 2014, 55 consecutive patients underwent SSRC by a single surgeon at Yonsei University Severance Hospital. Initially, 5 patients underwent the original robotic single site cholecystectomy technique, and the remaining 50 patients underwent robotic single site cholecystectomy using our reverse port technique.There were no differences between the SSRC-O (original port) group and the SSRC-R (reverse port) group in terms of patient age (P = 0.244), body mass index (P = 0.503), and pathologic conditions of the gallbladder (P = 0.841). Total operation time (132.6 vs 99.12 min; P = 0.009), actual dissection time (51.6 vs 30.28 min; P = 0.001), and console time (84.4 vs 50.46 min; P = 0.001) were all significantly shorter in the SSRC-R group. Mean intraoperative blood loss was minimal in both groups (20 vs 12.4 mL, P = 0.467), and bile spillage occurred in 2 patients of the SSRC-R group. There was one case of laparoscopic conversion in the SSRC-R group.The reverse port technique described in this study successfully widened Calot's triangle and improved the safety of the current robotic surgical system for single-site robotic cholecystectomy. ES - 1536-5964 IL - 0025-7974 DI - 00005792-201510030-00093 DO - https://dx.doi.org/10.1097/MD.0000000000001871 PT - Journal Article PT - Observational Study ID - 26496344 [pubmed] ID - 10.1097/MD.0000000000001871 [doi] ID - 00005792-201510030-00093 [pii] ID - PMC4620793 [pmc] PP - ppublish LG - English DP - 2015 Oct DC - 20151027 EZ - 2015/10/27 06:00 DA - 2016/04/29 06:00 DT - 2015/10/27 06:00 YR - 2015 ED - 20160428 RD - 20151028 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26496344 <102. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26254401 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kim JY AU - Lee YH AU - Chong GO AU - Lee YS AU - Cho YL AU - Hong DG FA - Kim, Joo Young FA - Lee, Yoon Hee FA - Chong, Gun Oh FA - Lee, Yoon Soon FA - Cho, Young Lae FA - Hong, Dae Gy IN - Kim, Joo Young. Department of Obstetrics and Gynecology, Kyungpook National University Medical Center, Graduate School of Medicine, Daegu, Republic of Korea. IN - Lee, Yoon Hee. Department of Obstetrics and Gynecology, Kyungpook National University Medical Center, Graduate School of Medicine, Daegu, Republic of Korea. IN - Chong, Gun Oh. Department of Obstetrics and Gynecology, Kyungpook National University Medical Center, Graduate School of Medicine, Daegu, Republic of Korea. IN - Lee, Yoon Soon. Department of Obstetrics and Gynecology, Kyungpook National University Medical Center, Graduate School of Medicine, Daegu, Republic of Korea. IN - Cho, Young Lae. Department of Obstetrics and Gynecology, Kyungpook National University Medical Center, Graduate School of Medicine, Daegu, Republic of Korea. IN - Hong, Dae Gy. Department of Obstetrics and Gynecology, Kyungpook National University Medical Center, Graduate School of Medicine, Daegu, Republic of Korea chssa02202002@yahoo.co.kr. TI - Comparative Study Between Total Laparoscopic and Total Robotic Radical Hysterectomy for Cervical Carcinoma: Clinical Study. SO - Anticancer Research. 35(9):5015-21, 2015 Sep AS - Anticancer Res. 35(9):5015-21, 2015 Sep NJ - Anticancer research PI - Journal available in: Print PI - Citation processed from: Internet JC - 59l, 8102988 IO - Anticancer Res. SB - Index Medicus CP - Greece MH - Female MH - Humans MH - *Hysterectomy MH - *Laparoscopy MH - Middle Aged MH - Quality of Life MH - *Robotics MH - Surveys and Questionnaires MH - Treatment Outcome MH - *Uterine Cervical Neoplasms/su [Surgery] KW - Cervical cancer; laparoscopy; quality of life; radical hysterectomy; robotic AB - AIM: to compare surgical outcomes and health-related quality of life (HRQOL) between total laparoscopic (TLRH) and total robotic radical hysterectomy (TRRH) for cervical cancer. AB - PATIENTS AND METHODS: Surgical outcomes and HRQOL were compared between the two groups. Pre- and postoperative HRQOL data from 36-item Short Form (SF-36) and European Organization Research and Treatment of Cancer Quality of Life-C30(EORTC QOL-C30) questionnaires were recorded. AB - RESULTS: In the TRRH group, there were more cases of para-aortic lymphadenectomy (p<0.01), longer operative time (p<0.01), less estimated blood loss (p<0.01), and more harvested pelvic lymph nodes (p=0.04). There were no significant differences in the SF-36 and the EORTC QOL-C30 between the two groups. AB - CONCLUSION: TRRH surgical outcomes were associated with less blood loss and more harvested pelvic lymph nodes but longer operative times with statistical significance. The short-term postoperative HRQOL outcomes did not show any significant inter-group differences. AB - Copyright© 2015 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved. ES - 1791-7530 IL - 0250-7005 DI - 35/9/5015 PT - Comparative Study PT - Journal Article ID - 26254401 [pubmed] ID - 35/9/5015 [pii] PP - ppublish LG - English DP - 2015 Sep DC - 20150808 EZ - 2015/08/09 06:00 DA - 2016/04/29 06:00 DT - 2015/08/09 06:00 YR - 2015 ED - 20160428 RD - 20150808 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26254401 <103. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25216924 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tasci AI AU - Tufek I AU - Gumus E AU - Canda AE AU - Tugcu V AU - Atug F AU - Boylu U AU - Akbulut Z AU - Sahin S AU - Simsek A AU - Kural AR FA - Tasci, A I FA - Tufek, I FA - Gumus, E FA - Canda, A E FA - Tugcu, V FA - Atug, F FA - Boylu, U FA - Akbulut, Z FA - Sahin, S FA - Simsek, A FA - Kural, A R IN - Tasci, A I. Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey. TI - Oncologic results, functional outcomes, and complication rates of robotic-assisted radical prostatectomy: multicenter experience in Turkey including 1,499 patients. SO - World Journal of Urology. 33(8):1095-102, 2015 Aug AS - World J Urol. 33(8):1095-102, 2015 Aug NJ - World journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - bry, 8307716 IO - World J Urol SB - Index Medicus CP - Germany MH - Adult MH - Aged MH - Humans MH - Kallikreins/bl [Blood] MH - Male MH - Middle Aged MH - Neoplasm Recurrence, Local/bl [Blood] MH - *Neoplasm Recurrence, Local/ep [Epidemiology] MH - Neoplasm Staging MH - *Postoperative Complications/ep [Epidemiology] MH - Prostate-Specific Antigen/bl [Blood] MH - *Prostatectomy MH - Prostatic Neoplasms/bl [Blood] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Retrospective Studies MH - *Robotic Surgical Procedures MH - *Sexual Dysfunction, Physiological/ep [Epidemiology] MH - Treatment Outcome MH - Turkey MH - *Urinary Incontinence/ep [Epidemiology] AB - BACKGROUND: Robot-assisted radical prostatectomy (RARP) is a rising minimally invasive treatment of localized prostate cancer (PC). We present our multicenter experience of 1,499 consecutive cases with an analysis of complication rates, oncologic, and functional outcomes. AB - PATIENTS AND METHODS: From March 2005 through December 2012, details of 1,499 patients were retrospectively analyzed. Transperitoneal approach using a da-Vinci robotic system was used to perform RARP. Perioperative characteristics and postoperative oncologic and functional outcomes are reported. AB - RESULTS: The mean age was 61.3 years (37-77). Mean PSA level was 8.3 ng/ml. According to D'Amico classification, the percentage of patients with low-, intermediate-, and high-risk disease cases were 65.0, 30.1, and 4.8 %, respectively. Mean operative time was 181.9 min. Mean estimated blood loss was 225.4 cc (30-1,250). Positive surgical margin (PSM) was detected in 212 (14.1 %) patients. PSM rates in pT2, pT3, and pT4 stages were 6.1, 37.1, and 100 %, respectively. The overall complication rate due to modified Clavien classification was 6.1 %. Mean follow-up time was 26.7 months. Continence, potency, and biochemical recurrence rates were 88.7, 58.2, and 2.9 %, respectively. AB - CONCLUSIONS: Our analyses including high-volume centers, which is the first largest series in Turkey, show that RARP is a safe procedure, has low PSM rates, high continence, and potency rates for the treatment of localized PC at experienced centers. RN - EC 3-4-21 (Kallikreins) RN - EC 3-4-21 (kallikrein-related peptidase 3, human) RN - EC 3-4-21-77 (Prostate-Specific Antigen) ES - 1433-8726 IL - 0724-4983 DO - https://dx.doi.org/10.1007/s00345-014-1393-3 PT - Clinical Study PT - Journal Article PT - Multicenter Study ID - 25216924 [pubmed] ID - 10.1007/s00345-014-1393-3 [doi] PP - ppublish PH - 2014/03/18 [received] PH - 2014/08/24 [accepted] LG - English EP - 20140913 DP - 2015 Aug DC - 20150723 EZ - 2014/09/14 06:00 DA - 2016/04/22 06:00 DT - 2014/09/14 06:00 YR - 2015 ED - 20160421 RD - 20150723 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25216924 <104. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26032118 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Torup H AU - Bogeskov M AU - Hansen EG AU - Palle C AU - Rosenberg J AU - Mitchell AU AU - Petersen PL AU - Mathiesen O AU - Dahl JB AU - Moller AM FA - Torup, H FA - Bogeskov, M FA - Hansen, E G FA - Palle, C FA - Rosenberg, J FA - Mitchell, A U FA - Petersen, P L FA - Mathiesen, O FA - Dahl, J B FA - Moller, A M IN - Torup, H. Department of Anaesthesiology, Herlev University Hospital, Copenhagen, Denmark. IN - Bogeskov, M. Department of Anaesthesiology, Herlev University Hospital, Copenhagen, Denmark. IN - Hansen, E G. Department of Anaesthesiology, Herlev University Hospital, Copenhagen, Denmark. IN - Palle, C. Department of Gynaecology, Herlev University Hospital, Copenhagen, Denmark. IN - Rosenberg, J. Department of Surgery, Herlev University Hospital, Copenhagen, Denmark. IN - Mitchell, A U. Department of Anaesthesiology, Herlev University Hospital, Copenhagen, Denmark. IN - Petersen, P L. Section of Acute Pain Management, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark. IN - Mathiesen, O. Section of Acute Pain Management, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark. IN - Dahl, J B. Department of Anaesthesiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark. IN - Moller, A M. Department of Anaesthesiology, Herlev University Hospital, Copenhagen, Denmark. TI - Transversus abdominis plane (TAP) block after robot-assisted laparoscopic hysterectomy: a randomised clinical trial. SO - Acta Anaesthesiologica Scandinavica. 59(7):928-35, 2015 Aug AS - Acta Anaesthesiol Scand. 59(7):928-35, 2015 Aug NJ - Acta anaesthesiologica Scandinavica PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 0370270 IO - Acta Anaesthesiol Scand SB - Index Medicus CP - England MH - Abdominal Muscles/de [Drug Effects] MH - *Abdominal Muscles/ir [Innervation] MH - Adult MH - *Amides MH - Analgesia, Patient-Controlled MH - Analgesics, Opioid/ad [Administration & Dosage] MH - Anesthetics, Local MH - Female MH - Humans MH - *Hysterectomy MH - *Laparoscopy MH - Middle Aged MH - Morphine/ad [Administration & Dosage] MH - *Nerve Block/mt [Methods] MH - *Pain, Postoperative/dt [Drug Therapy] MH - Prospective Studies MH - *Robotics MH - Single-Blind Method MH - Sodium Chloride/ad [Administration & Dosage] AB - BACKGROUND: Transversus abdominis plane (TAP) block is widely used as a part of pain management after various abdominal surgeries. We evaluated the effect of TAP block as an add-on to the routine analgesic regimen in patients undergoing robot-assisted laparoscopic hysterectomy. AB - METHODS: In a prospective blinded study, 70 patients scheduled for elective robot-assisted laparoscopic hysterectomy were randomised to receive either TAP block (ropivacaine 0.5%, 20 ml on each side) or sham block (isotonic saline 0.9%, 20 ml on each side). All patients had patient-controlled analgesia (PCA) with morphine on top of paracetamol and ibuprofen or diclofenac. For the first 24 post-operative hours, we monitored PCA morphine consumption and pain scores with visual analogue scale (VAS) at rest and while coughing. Post-operative nausea and number of vomits (PONV) were recorded. AB - RESULTS: Sixty-five patients completed the study, 34 receiving TAP block with ropivacaine and 31 receiving sham block with isotonic saline. We found no differences in median (interquartile range) morphine consumption the first 24 h between the TAP block group [17.5 mg (6.9-36.0 mg)] and the placebo group [17.5 mg (2.9-38.0 mg)] (95% confidence interval 10.0-22.6 mg, P = 0.648). No differences were found for VAS scores between the two groups, calculated as area under the curve/1-24 h, neither at rest (P = 0.112) nor while coughing (P = 0.345), or for PONV between groups. AB - CONCLUSIONS: In our study, the TAP block combined with paracetamol and Nonsteroidal anti-inflammatory drugs (NSAID) treatment, had no effect on morphine consumption, VAS pain scores, or frequency of nausea and vomiting after robot-assisted laparoscopic hysterectomy compared with paracetamol and NSAID alone. AB - Copyright © 2015 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd. RN - 0 (Amides) RN - 0 (Analgesics, Opioid) RN - 0 (Anesthetics, Local) RN - 451W47IQ8X (Sodium Chloride) RN - 76I7G6D29C (Morphine) RN - 7IO5LYA57N (ropivacaine) ES - 1399-6576 IL - 0001-5172 DO - https://dx.doi.org/10.1111/aas.12516 PT - Journal Article PT - Randomized Controlled Trial ID - 26032118 [pubmed] ID - 10.1111/aas.12516 [doi] PP - ppublish PH - 2015/02/10 [revised] PH - 2015/02/24 [accepted] PH - 2014/07/31 [received] LG - English EP - 20150531 DP - 2015 Aug DC - 20150716 EZ - 2015/06/03 06:00 DA - 2016/04/19 06:00 DT - 2015/06/03 06:00 YR - 2015 ED - 20160418 RD - 20150716 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26032118 <105. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26020107 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kim HI AU - Han SU AU - Yang HK AU - Kim YW AU - Lee HJ AU - Ryu KW AU - Park JM AU - An JY AU - Kim MC AU - Park S AU - Song KY AU - Oh SJ AU - Kong SH AU - Suh BJ AU - Yang DH AU - Ha TK AU - Kim YN AU - Hyung WJ FA - Kim, Hyoung-Il FA - Han, Sang-Uk FA - Yang, Han-Kwang FA - Kim, Young-Woo FA - Lee, Hyuk-Joon FA - Ryu, Keun Won FA - Park, Joong-Min FA - An, Ji Yeong FA - Kim, Min-Chan FA - Park, Sungsoo FA - Song, Kyo Young FA - Oh, Sung Jin FA - Kong, Seong-Ho FA - Suh, Byoung Jo FA - Yang, Dae Hyun FA - Ha, Tae Kyung FA - Kim, Youn Nam FA - Hyung, Woo Jin IN - Kim, Hyoung-Il. *Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea +Gastric Cancer Center, Yonsei Cancer Center, Seoul, Republic of Korea ++Robot & MIS Center, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea Department of Surgery, Ajou University College of Medicine, Seoul, Republic of Korea PDepartment of Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea IN - IN - Center for Gastric Cancer, National Cancer Center, Seoul, Republic of Korea **Department of Surgery, Chung-Ang University College of Medicine, Seoul, Republic of Korea ++Department of Surgery, Dong-A University College of Medicine, Seoul, Republic of Korea ++++Department of Surgery, Korea University College of Medicine, Seoul, Republic of Korea Department of Surgery, The Catholic University of Korea, Seoul, Republic of Korea PPDepartment of Surgery, Inje University College of Medicine, Seoul, Republic of Korea IN - IN - IN - IN - Department of Surgery, Hallym University College of Medicine, Seoul, Republic of Korea ***Department of Surgery, Hanyang University College of Medicine, Seoul, Republic of Korea +++Department of Biostatistics, Yonsei University College of Medicine, Seoul, Republic of Korea. TI - Multicenter Prospective Comparative Study of Robotic Versus Laparoscopic Gastrectomy for Gastric Adenocarcinoma. SO - Annals of Surgery. 263(1):103-9, 2016 Jan AS - Ann Surg. 263(1):103-9, 2016 Jan NJ - Annals of surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 67s, 0372354 IO - Ann. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - *Adenocarcinoma/su [Surgery] MH - Costs and Cost Analysis MH - Female MH - Gastrectomy/ec [Economics] MH - *Gastrectomy/mt [Methods] MH - Humans MH - Laparoscopy/ec [Economics] MH - *Laparoscopy MH - Male MH - Middle Aged MH - Prospective Studies MH - Robotic Surgical Procedures/ec [Economics] MH - *Robotic Surgical Procedures MH - *Stomach Neoplasms/su [Surgery] AB - OBJECTIVE: To compare short-term surgical outcomes including financial cost of robotic and laparoscopic gastrectomy. AB - BACKGROUND: Despite a lack of supporting evidence, robotic surgery has been increasingly adopted as a minimally invasive modality for the treatment of gastric cancer because of its assumed technical superiority over conventional laparoscopy. AB - METHODS: A prospective, multicenter comparative study was conducted. Patients were matched according to the surgeon, extent of gastric resection, and sex. The primary endpoint was morbidity and mortality. Outcomes were analyzed on an intention-to-treat and per-protocol basis. AB - RESULTS: A total of 434 patients were enrolled for treatment with either robotic (n = 223) or laparoscopic (n = 211) gastrectomy for intention-to-treat analysis, and a total of 370 patients (n = 185 per treatment) were compared in per-protocol analysis. Results were similar between both analyses. In per-protocol analysis, both groups showed similar overall complication rates (robotic = 11.9% vs laparoscopic = 10.3%) and major complication rates (robotic = 1.1% vs laparoscopic = 1.1%) with no operative mortality in either group. Patients treated with robotic surgery showed significantly longer operative time (robotic = 221 minutes vs laparoscopic = 178 minutes; P < 0.001) and significantly higher total costs (robotic = US$13,432 vs laparoscopic = US$8090; P < 0.001), compared with those who underwent laparoscopic gastrectomy. No significant differences between groups were noted in estimated blood loss, rates of open conversion, diet build-up, or length of hospital stay. AB - CONCLUSIONS: The use of robotic systems is assumed to provide a technically superior operative environment for minimally invasive surgery. However, our analysis of perioperative surgical outcomes indicated that robotic gastrectomy is not superior to laparoscopic gastrectomy. Clinical trials identification: NCT01309256. ES - 1528-1140 IL - 0003-4932 DO - https://dx.doi.org/10.1097/SLA.0000000000001249 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Research Support, Non-U.S. Gov't ID - 26020107 [pubmed] ID - 10.1097/SLA.0000000000001249 [doi] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01309256 SL - https://clinicaltrials.gov/search/term=NCT01309256 LG - English DP - 2016 Jan DC - 20151217 EZ - 2015/05/29 06:00 DA - 2016/04/15 06:00 DT - 2015/05/29 06:00 YR - 2016 ED - 20160414 RD - 20151217 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26020107 <106. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26176381 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Haga N AU - Yanagida T AU - Yabe M AU - Akaihata H AU - Hata J AU - Sato Y AU - Ogawa S AU - Ishibashi K AU - Kojima Y FA - Haga, Nobuhiro FA - Yanagida, Tomohiko FA - Yabe, Michihiro FA - Akaihata, Hidenori FA - Hata, Junya FA - Sato, Yuichi FA - Ogawa, Soichiro FA - Ishibashi, Kei FA - Kojima, Yoshiyuki IN - Haga, Nobuhiro. Department of Urology, Fukushima Medical University School of Medicine , Fukushima, Japan . IN - Yanagida, Tomohiko. Department of Urology, Fukushima Medical University School of Medicine , Fukushima, Japan . IN - Yabe, Michihiro. Department of Urology, Fukushima Medical University School of Medicine , Fukushima, Japan . IN - Akaihata, Hidenori. Department of Urology, Fukushima Medical University School of Medicine , Fukushima, Japan . IN - Hata, Junya. Department of Urology, Fukushima Medical University School of Medicine , Fukushima, Japan . IN - Sato, Yuichi. Department of Urology, Fukushima Medical University School of Medicine , Fukushima, Japan . IN - Ogawa, Soichiro. Department of Urology, Fukushima Medical University School of Medicine , Fukushima, Japan . IN - Ishibashi, Kei. Department of Urology, Fukushima Medical University School of Medicine , Fukushima, Japan . IN - Kojima, Yoshiyuki. Department of Urology, Fukushima Medical University School of Medicine , Fukushima, Japan . TI - Timing of Urinary Pad Exchanges Was the Most Important Factor Affecting Quality of Life in the Early Postoperative Period After Robot-Assisted Laparoscopic Radical Prostatectomy. SO - Journal of Endourology. 29(9):1044-51, 2015 Sep AS - J Endourol. 29(9):1044-51, 2015 Sep NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Aged MH - Catheterization MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Postoperative Period MH - Prospective Studies MH - Prostate/su [Surgery] MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - *Prostatic Diseases/su [Surgery] MH - *Quality of Life MH - *Robotic Surgical Procedures MH - Surgery, Computer-Assisted/ae [Adverse Effects] MH - Surveys and Questionnaires MH - Time Factors MH - Treatment Outcome MH - *Urinary Incontinence/et [Etiology] MH - Urinary Incontinence/rh [Rehabilitation] AB - PURPOSE: The aim of the present study is to investigate the effect of pad use for postprostatectomy incontinence on urinary quality of life (QoL) after robot-assisted laparoscopic radical prostatectomy (RARP) in the early postoperative period. AB - METHODS: Ninety patients underwent RARP simultaneously completed International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) and modified pad use questionnaire that evaluated pad use and urinary QoL and a 24-hour pad test. Pad use was also assessed by pad form, pad size, the number of pad exchanges per day, and the timing of pad exchanges (i.e., to what extent the pad was wet when the patients exchanged it.). The investigation involved patients visiting the outpatient clinic for the first time after RARP. The association between pad use and urinary QoL was investigated. AB - RESULTS: The mean frequency of pad exchanges was 2+/-2/day. The mean 24-hour pad test was 139+/-193g/day. Multivariate analyses revealed the timing of pad exchanges was significantly associated with QoL on the ICIQ-SF and the modified pad use questionnaire (P=0.007 and P<0.001, respectively) and the number of pad exchanges per day was significantly associated with QoL on the ICIQ-SF (P=0.01); QoL worsened with pad wetness and increasing frequency of pad exchange. The other factors relating to pad use were not significantly associated with aggravation of QoL. AB - CONCLUSIONS: In the early postoperative period after RARP, the timing of pad exchanges was the most important factor affecting QoL. Namely, patients with postprostatectomy incontinence should wear the appropriate size of pad according to the volume of urinary incontinence and exchange pads when the pad is not too wet. On the other hand, pad form, pad size, and volume of urinary incontinence were not associated with decreased QoL. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2015.0326 PT - Journal Article PT - Observational Study ID - 26176381 [pubmed] ID - 10.1089/end.2015.0326 [doi] PP - ppublish LG - English EP - 20150715 DP - 2015 Sep DC - 20150902 EZ - 2015/07/16 06:00 DA - 2016/04/15 06:00 DT - 2015/07/16 06:00 YR - 2015 ED - 20160414 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26176381 <107. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25897552 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Knight RB AU - Walker PW AU - Keegan KA AU - Overholser SM AU - Baumgartner TS AU - Ebertowski JS 2nd AU - Aden JK AU - White MA FA - Knight, Richard B FA - Walker, Paul W FA - Keegan, Kirk A FA - Overholser, Stephen M FA - Baumgartner, Timothy S FA - Ebertowski, James S 2nd FA - Aden, James K FA - White, Michael A IN - Knight, Richard B. 1 Department of Urology, 48th MDG, RAF Lakenheath , Brandon, Suffolk, United Kingdom . IN - Walker, Paul W. 2 Louisiana Urology , LLC, Baton Rouge, Louisiana. IN - Keegan, Kirk A. 3 Department of Urology, San Antonio Military Medical Center , Fort Sam Houston, Texas. IN - Overholser, Stephen M. 4 University of Texas Health Science Center at San Antonio , San Antonio, Texas. IN - Baumgartner, Timothy S. 3 Department of Urology, San Antonio Military Medical Center , Fort Sam Houston, Texas. IN - Ebertowski, James S 2nd. 3 Department of Urology, San Antonio Military Medical Center , Fort Sam Houston, Texas. IN - Aden, James K. 3 Department of Urology, San Antonio Military Medical Center , Fort Sam Houston, Texas. IN - White, Michael A. 5 Urology San Antonio , San Antonio, Texas. TI - A Randomized Controlled Trial for Pain Control in Laparoscopic Urologic Surgery: 0.25% Bupivacaine Versus Long-Acting Liposomal Bupivacaine. SO - Journal of Endourology. 29(9):1019-24, 2015 Sep AS - J Endourol. 29(9):1019-24, 2015 Sep NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Aged MH - *Analgesics, Opioid/ad [Administration & Dosage] MH - *Anesthetics, Local/ad [Administration & Dosage] MH - *Bupivacaine/ad [Administration & Dosage] MH - Female MH - Humans MH - *Laparoscopy/mt [Methods] MH - Length of Stay MH - *Liposomes/ch [Chemistry] MH - Male MH - Middle Aged MH - Pain Management MH - Pain Measurement MH - Pain, Postoperative/dt [Drug Therapy] MH - Prospective Studies MH - Robotic Surgical Procedures MH - Surgery, Computer-Assisted MH - *Urologic Surgical Procedures/mt [Methods] AB - BACKGROUND AND PURPOSE: Liposomal bupivacaine is a delayed-release preparation providing up to 72 hours of local analgesia. It costs much more than standard bupivacaine, however. A prospective, randomized, patient-blinded, controlled trial was performed to assess the efficacy of liposomal bupivacaine versus 0.25% bupivacaine when injected into surgical incisions during laparoscopic and robot-assisted urologic surgery. AB - METHODS: A total of 206 adults were randomized to receive liposomal bupivacaine or 0.25% bupivacaine. All surgical incisions were injected with liposomal bupivacaine or 0.25% bupivacaine with systematic dosing. The primary outcome was total opioid consumption during the postoperative hospital stay. All opioid doses were converted to morphine equivalents. Secondary end points included pain scores using visual analog pain scales, duration of hospital stay, and the time to first opioid use. A subgroup analysis was performed for renal surgery patients. AB - RESULTS: There was no significant difference in median total opioid use during the hospital stay between those who received liposomal bupivacaine (15 [interquartile range (IQR) 6.7-27] mg) and 0.25% bupivacaine (17.3 [IQR 8.3-30.5] mg) (P=0.39). Furthermore, pain scores, length of hospital stay, and time to first opioid use did not differ between groups. Subgroup analysis of laparoscopic renal surgery revealed no difference between liposomal bupivacaine and 0.25% bupivacaine. AB - CONCLUSIONS: For laparoscopic and robot-assisted urologic surgery, there is no significant difference between liposomal bupivacaine and 0.25% bupivacaine for local analgesia at the incision sites. RN - 0 (Analgesics, Opioid) RN - 0 (Anesthetics, Local) RN - 0 (Liposomes) RN - Y8335394RO (Bupivacaine) ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2014.0769 PT - Journal Article PT - Randomized Controlled Trial ID - 25897552 [pubmed] ID - 10.1089/end.2014.0769 [doi] PP - ppublish LG - English EP - 20150605 DP - 2015 Sep DC - 20150902 EZ - 2015/04/22 06:00 DA - 2016/04/15 06:00 DT - 2015/04/22 06:00 YR - 2015 ED - 20160414 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25897552 <108. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26020107 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kim HI AU - Han SU AU - Yang HK AU - Kim YW AU - Lee HJ AU - Ryu KW AU - Park JM AU - An JY AU - Kim MC AU - Park S AU - Song KY AU - Oh SJ AU - Kong SH AU - Suh BJ AU - Yang DH AU - Ha TK AU - Kim YN AU - Hyung WJ FA - Kim, Hyoung-Il FA - Han, Sang-Uk FA - Yang, Han-Kwang FA - Kim, Young-Woo FA - Lee, Hyuk-Joon FA - Ryu, Keun Won FA - Park, Joong-Min FA - An, Ji Yeong FA - Kim, Min-Chan FA - Park, Sungsoo FA - Song, Kyo Young FA - Oh, Sung Jin FA - Kong, Seong-Ho FA - Suh, Byoung Jo FA - Yang, Dae Hyun FA - Ha, Tae Kyung FA - Kim, Youn Nam FA - Hyung, Woo Jin IN - Kim, Hyoung-Il. *Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea +Gastric Cancer Center, Yonsei Cancer Center, Seoul, Republic of Korea ++Robot & MIS Center, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea Department of Surgery, Ajou University College of Medicine, Seoul, Republic of Korea PDepartment of Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea IN - IN - Center for Gastric Cancer, National Cancer Center, Seoul, Republic of Korea **Department of Surgery, Chung-Ang University College of Medicine, Seoul, Republic of Korea ++Department of Surgery, Dong-A University College of Medicine, Seoul, Republic of Korea ++++Department of Surgery, Korea University College of Medicine, Seoul, Republic of Korea Department of Surgery, The Catholic University of Korea, Seoul, Republic of Korea PPDepartment of Surgery, Inje University College of Medicine, Seoul, Republic of Korea IN - IN - IN - IN - Department of Surgery, Hallym University College of Medicine, Seoul, Republic of Korea ***Department of Surgery, Hanyang University College of Medicine, Seoul, Republic of Korea +++Department of Biostatistics, Yonsei University College of Medicine, Seoul, Republic of Korea. TI - Multicenter Prospective Comparative Study of Robotic Versus Laparoscopic Gastrectomy for Gastric Adenocarcinoma. CM - Comment in: Transl Gastroenterol Hepatol. 2016 Apr 13;1:33; PMID: 28138600 SO - Annals of Surgery. 263(1):103-9, 2016 Jan AS - Ann Surg. 263(1):103-9, 2016 Jan NJ - Annals of surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 67s, 0372354 IO - Ann. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - *Adenocarcinoma/su [Surgery] MH - Costs and Cost Analysis MH - Female MH - Gastrectomy/ec [Economics] MH - *Gastrectomy/mt [Methods] MH - Humans MH - Laparoscopy/ec [Economics] MH - *Laparoscopy MH - Male MH - Middle Aged MH - Prospective Studies MH - Robotic Surgical Procedures/ec [Economics] MH - *Robotic Surgical Procedures MH - *Stomach Neoplasms/su [Surgery] AB - OBJECTIVE: To compare short-term surgical outcomes including financial cost of robotic and laparoscopic gastrectomy. AB - BACKGROUND: Despite a lack of supporting evidence, robotic surgery has been increasingly adopted as a minimally invasive modality for the treatment of gastric cancer because of its assumed technical superiority over conventional laparoscopy. AB - METHODS: A prospective, multicenter comparative study was conducted. Patients were matched according to the surgeon, extent of gastric resection, and sex. The primary endpoint was morbidity and mortality. Outcomes were analyzed on an intention-to-treat and per-protocol basis. AB - RESULTS: A total of 434 patients were enrolled for treatment with either robotic (n = 223) or laparoscopic (n = 211) gastrectomy for intention-to-treat analysis, and a total of 370 patients (n = 185 per treatment) were compared in per-protocol analysis. Results were similar between both analyses. In per-protocol analysis, both groups showed similar overall complication rates (robotic = 11.9% vs laparoscopic = 10.3%) and major complication rates (robotic = 1.1% vs laparoscopic = 1.1%) with no operative mortality in either group. Patients treated with robotic surgery showed significantly longer operative time (robotic = 221 minutes vs laparoscopic = 178 minutes; P < 0.001) and significantly higher total costs (robotic = US$13,432 vs laparoscopic = US$8090; P < 0.001), compared with those who underwent laparoscopic gastrectomy. No significant differences between groups were noted in estimated blood loss, rates of open conversion, diet build-up, or length of hospital stay. AB - CONCLUSIONS: The use of robotic systems is assumed to provide a technically superior operative environment for minimally invasive surgery. However, our analysis of perioperative surgical outcomes indicated that robotic gastrectomy is not superior to laparoscopic gastrectomy. Clinical trials identification: NCT01309256. ES - 1528-1140 IL - 0003-4932 DO - https://dx.doi.org/10.1097/SLA.0000000000001249 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Research Support, Non-U.S. Gov't ID - 26020107 [pubmed] ID - 10.1097/SLA.0000000000001249 [doi] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01309256 SL - https://clinicaltrials.gov/search/term=NCT01309256 LG - English DP - 2016 Jan DC - 20151217 EZ - 2015/05/29 06:00 DA - 2016/04/15 06:00 DT - 2015/05/29 06:00 YR - 2016 ED - 20160414 RD - 20170131 UP - 20170201 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=26020107 <109. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25770484 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Haglind E AU - Carlsson S AU - Stranne J AU - Wallerstedt A AU - Wilderang U AU - Thorsteinsdottir T AU - Lagerkvist M AU - Damber JE AU - Bjartell A AU - Hugosson J AU - Wiklund P AU - Steineck G AU - LAPPRO steering committee FA - Haglind, Eva FA - Carlsson, Stefan FA - Stranne, Johan FA - Wallerstedt, Anna FA - Wilderang, Ulrica FA - Thorsteinsdottir, Thordis FA - Lagerkvist, Mikael FA - Damber, Jan-Erik FA - Bjartell, Anders FA - Hugosson, Jonas FA - Wiklund, Peter FA - Steineck, Gunnar FA - LAPPRO steering committee IN - Haglind, Eva. Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg and Sahlgrenska University Hospital, Goteborg, Sweden. Electronic address: eva.haglind@vgregion.se. IN - Carlsson, Stefan. Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institutet, Stockholm, Sweden. IN - Stranne, Johan. Department of Urology, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital, Goteborg, Sweden. IN - Wallerstedt, Anna. Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institutet, Stockholm, Sweden. IN - Wilderang, Ulrica. Division of Clinical Cancer Epidemiology, Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Goteborg, Sweden. IN - Thorsteinsdottir, Thordis. Division of Clinical Cancer Epidemiology, Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Goteborg, Sweden; Faculty of Nursing, School of Health Sciences, University of Iceland, Reykjavik, Iceland. IN - Lagerkvist, Mikael. UroClinic, Stockholm, Sweden. IN - Damber, Jan-Erik. Department of Urology, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital, Goteborg, Sweden. IN - Bjartell, Anders. Department of Urology, Skane University Hospital, Lund University, Malmo, Sweden. IN - Hugosson, Jonas. Department of Urology, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital, Goteborg, Sweden. IN - Wiklund, Peter. Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institutet, Stockholm, Sweden. IN - Steineck, Gunnar. Division of Clinical Cancer Epidemiology, Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Goteborg, Sweden; Department of Oncology and Pathology, Division of Clinical Cancer Epidemiology, Karolinska Institutet, Stockholm, Sweden. IR - Anderberg B IR - Bjorholt I IR - Jiborn T IR - Gustafsson O IR - Khatami A IR - Wulker-Sylme M IR - Edlund C IR - Pileblad E IR - Boman H IR - Bratt O IR - Westlund U TI - Urinary Incontinence and Erectile Dysfunction After Robotic Versus Open Radical Prostatectomy: A Prospective, Controlled, Nonrandomised Trial. CM - Comment in: Eur Urol. 2015 Aug;68(2):226-7; PMID: 25824721 CM - Comment in: J Urol. 2015 Sep;194(3):706; PMID: 26292863 CM - Comment in: J Urol. 2016 Feb;195(2):354; PMID: 26852978 SO - European Urology. 68(2):216-25, 2015 Aug AS - Eur Urol. 68(2):216-25, 2015 Aug NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Aged MH - Erectile Dysfunction/di [Diagnosis] MH - *Erectile Dysfunction/et [Etiology] MH - Humans MH - Incontinence Pads MH - *Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/mt [Methods] MH - Logistic Models MH - Male MH - Middle Aged MH - Neoplasm, Residual MH - Odds Ratio MH - Prospective Studies MH - *Prostatectomy/ae [Adverse Effects] MH - Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Risk Factors MH - *Robotic Surgical Procedures/ae [Adverse Effects] MH - Robotic Surgical Procedures/mt [Methods] MH - Surveys and Questionnaires MH - Sweden MH - Time Factors MH - Treatment Outcome MH - Urinary Incontinence/di [Diagnosis] MH - *Urinary Incontinence/et [Etiology] MH - Urinary Incontinence/th [Therapy] KW - Erectile dysfunction; Open radical prostatectomy; Prostate cancer; Robot-assisted laparoscopic radical prostatectomy; Urinary incontinence AB - BACKGROUND: Robot-assisted laparoscopic radical prostatectomy (RALP) has become widely used without high-grade evidence of superiority regarding long-term clinical outcomes compared with open retropubic radical prostatectomy (RRP), the gold standard. AB - OBJECTIVE: To compare patient-reported urinary incontinence and erectile dysfunction 12 mo after RALP or RRP. AB - DESIGN, SETTING, AND PARTICIPANTS: This was a prospective, controlled, nonrandomised trial of patients undergoing prostatectomy in 14 centres using RALP or RRP. Clinical-record forms and validated patient questionnaires at baseline and 12 mo after surgery were collected. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSES: Odds ratios (ORs) were calculated with logistic regression and adjusted for possible confounders. The primary end point was urinary incontinence (change of pad less than once in 24h vs one time or more per 24h) at 12 mo. Secondary end points were erectile dysfunction at 12 mo and positive surgical margins. AB - RESULTS AND LIMITATIONS: Of 2625 eligible men, 2431 (93%) could be evaluated for the primary end point. At 12 mo after RALP, 366 men (21.3%) were incontinent, as were 144 (20.2%) after RRP. The adjusted OR was 1.08 (95% confidence interval [CI], 0.87-1.34). Erectile dysfunction was observed in 1200 men (70.4%) 12 mo after RALP and 531 (74.7%) after RRP. The adjusted OR was 0.81 (95% CI, 0.66-0.98). The frequency of positive surgical margins did not differ significantly between groups: 21.8% in the RALP group and 20.9% in the RRP group (adjusted OR: 1.09; 95% CI, 0.87-1.35). The nonrandomised design is a limitation. AB - CONCLUSIONS: In a Swedish setting, RALP for prostate cancer was modestly beneficial in preserving erectile function compared with RRP, without a statistically significant difference regarding urinary incontinence or surgical margins. AB - PATIENT SUMMARY: We compared patient-reported urinary incontinence after prostatectomy with two types of surgical technique. There was no statistically significant improvement in the rate of urinary leakage, but there was a small improvement regarding erectile function after robot-assisted operation. AB - Copyright © 2015 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(15)00194-3 DO - https://dx.doi.org/10.1016/j.eururo.2015.02.029 PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article PT - Multicenter Study PT - Research Support, Non-U.S. Gov't ID - 25770484 [pubmed] ID - S0302-2838(15)00194-3 [pii] ID - 10.1016/j.eururo.2015.02.029 [doi] PP - ppublish PH - 2014/11/19 [received] PH - 2015/02/25 [accepted] LG - English EP - 20150312 DP - 2015 Aug DC - 20150707 EZ - 2015/03/16 06:00 DA - 2016/04/12 06:00 DT - 2015/03/17 06:00 YR - 2015 ED - 20160411 RD - 20160606 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25770484 <110. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25496767 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bochner BH AU - Dalbagni G AU - Sjoberg DD AU - Silberstein J AU - Keren Paz GE AU - Donat SM AU - Coleman JA AU - Mathew S AU - Vickers A AU - Schnorr GC AU - Feuerstein MA AU - Rapkin B AU - Parra RO AU - Herr HW AU - Laudone VP FA - Bochner, Bernard H FA - Dalbagni, Guido FA - Sjoberg, Daniel D FA - Silberstein, Jonathan FA - Keren Paz, Gal E FA - Donat, S Machele FA - Coleman, Jonathan A FA - Mathew, Sheila FA - Vickers, Andrew FA - Schnorr, Geoffrey C FA - Feuerstein, Michael A FA - Rapkin, Bruce FA - Parra, Raul O FA - Herr, Harry W FA - Laudone, Vincent P IN - Bochner, Bernard H. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: bochnerb@mskcc.org. IN - Dalbagni, Guido. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Sjoberg, Daniel D. Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Silberstein, Jonathan. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Urology, Tulane University School of Medicine, New Orleans, LA, USA. IN - Keren Paz, Gal E. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Donat, S Machele. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Coleman, Jonathan A. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Mathew, Sheila. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Vickers, Andrew. Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Schnorr, Geoffrey C. Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Feuerstein, Michael A. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Rapkin, Bruce. Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA. IN - Parra, Raul O. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Herr, Harry W. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Laudone, Vincent P. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. TI - Comparing Open Radical Cystectomy and Robot-assisted Laparoscopic Radical Cystectomy: A Randomized Clinical Trial. CM - Comment in: J Urol. 2015 Dec;194(6):1584-5; PMID: 26582662 CM - Comment in: Eur Urol. 2015 Jun;67(6):1053-5; PMID: 25641689 CM - Comment in: Eur Urol. 2015 Jun;67(6):1051-2; PMID: 25650270 SO - European Urology. 67(6):1042-50, 2015 Jun AS - Eur Urol. 67(6):1042-50, 2015 Jun NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424172 OI - Source: NLM. NIHMS656563 SB - Index Medicus CP - Switzerland MH - Adult MH - Aged MH - Aged, 80 and over MH - Blood Loss, Surgical/sn [Statistics & Numerical Data] MH - *Cystectomy/is [Instrumentation] MH - *Cystectomy/mt [Methods] MH - Female MH - Humans MH - *Laparoscopy/is [Instrumentation] MH - Laparoscopy/mt [Methods] MH - Lymph Node Excision/is [Instrumentation] MH - Lymph Node Excision/mt [Methods] MH - Male MH - Middle Aged MH - Operative Time MH - Pelvis/pa [Pathology] MH - Postoperative Complications/ep [Epidemiology] MH - Prospective Studies MH - Quality of Life MH - Robotic Surgical Procedures/is [Instrumentation] MH - *Robotic Surgical Procedures/mt [Methods] MH - Treatment Outcome MH - Urinary Bladder Neoplasms/pa [Pathology] MH - *Urinary Bladder Neoplasms/su [Surgery] MH - Urinary Diversion/is [Instrumentation] MH - Urinary Diversion/mt [Methods] KW - Bladder cancer; Complications; Cystectomy; Lymph node dissection; Quality of life; Randomized controlled trial; Robot assisted; Robotic; Urinary diversion AB - BACKGROUND: Open radical cystectomy (ORC) and urinary diversion in patients with bladder cancer (BCa) are associated with significant perioperative complication risk. AB - OBJECTIVE: To compare perioperative complications between robot-assisted radical cystectomy (RARC) and ORC techniques. AB - DESIGN, SETTING, AND PARTICIPANTS: A prospective randomized controlled trial was conducted during 2010 and 2013 in BCa patients scheduled for definitive treatment by radical cystectomy (RC), pelvic lymph node dissection (PLND), and urinary diversion. Patients were randomized to ORC/PLND or RARC/PLND, both with open urinary diversion. Patients were followed for 90 d postoperatively. AB - INTERVENTION: Standard ORC or RARC with PLND; all urinary diversions were performed via an open approach. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Primary outcomes were overall 90-d grade 2-5 complications defined by a modified Clavien system. Secondary outcomes included comparison of high-grade complications, estimated blood loss, operative time, pathologic outcomes, 3- and 6-mo patient-reported quality-of-life (QOL) outcomes, and total operative room and inpatient costs. Differences in binary outcomes were assessed with the chi-square test, with differences in continuous outcomes assessed by analysis of covariance with randomization group as covariate and, for QOL end points, baseline score. AB - RESULTS AND LIMITATIONS: The trial enrolled 124 patients, of whom 118 were randomized and underwent RC/PLND. Sixty were randomized to RARC and 58 to ORC. At 90 d, grade 2-5 complications were observed in 62% and 66% of RARC and ORC patients, respectively (95% confidence interval for difference, -21% to -13%; p=0.7). The similar rates of grade 2-5 complications at our mandated interim analysis met futility criteria; thus, early closure of the trial occurred. The RARC group had lower mean intraoperative blood loss (p=0.027) but significantly longer operative time than the ORC group (p<0.001). Pathologic variables including positive surgical margins and lymph node yields were similar. Mean hospital stay was 8 d in both arms (standard deviation, 3 and 5 d, respectively; p=0.5). Three- and 6-mo QOL outcomes were similar between arms. Cost analysis demonstrated an advantage to ORC compared with RARC. A limitation is the setting at a single high-volume, referral center; our findings may not be generalizable to all settings. AB - CONCLUSIONS: This trial failed to identify a large advantage for robot-assisted techniques over standard open surgery for patients undergoing RC/PLND and urinary diversion. Similar 90-d complication rates, hospital stay, pathologic outcomes, and 3- and 6-mo QOL outcomes were observed regardless of surgical technique. AB - PATIENT SUMMARY: Of 118 patients with bladder cancer who underwent radical cystectomy, pelvic lymph node dissection, and urinary diversion, half were randomized to open surgery and half to robot-assisted laparoscopic surgery. We compared the rate of complications within 90 d after surgery for the open group versus the robotic group and found no significant difference between the two groups. AB - TRIAL REGISTRATION: ClinicalTrials.gov identifier NCT01076387, www.clinicaltrials.gov. AB - Copyright © 2014 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(14)01235-4 DO - https://dx.doi.org/10.1016/j.eururo.2014.11.043 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 25496767 [pubmed] ID - S0302-2838(14)01235-4 [pii] ID - 10.1016/j.eururo.2014.11.043 [doi] ID - PMC4424172 [pmc] ID - NIHMS656563 [mid] PP - ppublish PH - 2014/09/26 [received] PH - 2014/11/21 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01076387 SA - ClinicalTrials.gov/NCT01076387 SL - https://clinicaltrials.gov/search/term=NCT01076387 SL - https://clinicaltrials.gov/search/term=NCT01076387 GI - No: P30 CA008748 Organization: (CA) *NCI NIH HHS* Country: United States No: T32 CA082088 Organization: (CA) *NCI NIH HHS* Country: United States LG - English EP - 20141208 DP - 2015 Jun DC - 20150506 EZ - 2014/12/16 06:00 DA - 2016/04/08 06:00 DT - 2014/12/17 06:00 YR - 2015 ED - 20160407 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25496767 <111. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25496767 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bochner BH AU - Dalbagni G AU - Sjoberg DD AU - Silberstein J AU - Keren Paz GE AU - Donat SM AU - Coleman JA AU - Mathew S AU - Vickers A AU - Schnorr GC AU - Feuerstein MA AU - Rapkin B AU - Parra RO AU - Herr HW AU - Laudone VP FA - Bochner, Bernard H FA - Dalbagni, Guido FA - Sjoberg, Daniel D FA - Silberstein, Jonathan FA - Keren Paz, Gal E FA - Donat, S Machele FA - Coleman, Jonathan A FA - Mathew, Sheila FA - Vickers, Andrew FA - Schnorr, Geoffrey C FA - Feuerstein, Michael A FA - Rapkin, Bruce FA - Parra, Raul O FA - Herr, Harry W FA - Laudone, Vincent P IN - Bochner, Bernard H. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: bochnerb@mskcc.org. IN - Dalbagni, Guido. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Sjoberg, Daniel D. Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Silberstein, Jonathan. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Urology, Tulane University School of Medicine, New Orleans, LA, USA. IN - Keren Paz, Gal E. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Donat, S Machele. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Coleman, Jonathan A. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Mathew, Sheila. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Vickers, Andrew. Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Schnorr, Geoffrey C. Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Feuerstein, Michael A. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Rapkin, Bruce. Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA. IN - Parra, Raul O. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Herr, Harry W. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Laudone, Vincent P. Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. TI - Comparing Open Radical Cystectomy and Robot-assisted Laparoscopic Radical Cystectomy: A Randomized Clinical Trial. CM - Comment in: J Urol. 2015 Dec;194(6):1584-5; PMID: 26582662 CM - Comment in: Eur Urol. 2015 Jun;67(6):1053-5; PMID: 25641689 CM - Comment in: Eur Urol. 2015 Jun;67(6):1051-2; PMID: 25650270 SO - European Urology. 67(6):1042-50, 2015 Jun AS - Eur Urol. 67(6):1042-50, 2015 Jun NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424172 OI - Source: NLM. NIHMS656563 SB - Index Medicus CP - Switzerland MH - Adult MH - Aged MH - Aged, 80 and over MH - Blood Loss, Surgical/sn [Statistics & Numerical Data] MH - *Cystectomy/is [Instrumentation] MH - *Cystectomy/mt [Methods] MH - Female MH - Humans MH - *Laparoscopy/is [Instrumentation] MH - Laparoscopy/mt [Methods] MH - Lymph Node Excision/is [Instrumentation] MH - Lymph Node Excision/mt [Methods] MH - Male MH - Middle Aged MH - Operative Time MH - Pelvis/pa [Pathology] MH - Postoperative Complications/ep [Epidemiology] MH - Prospective Studies MH - Quality of Life MH - Robotic Surgical Procedures/is [Instrumentation] MH - *Robotic Surgical Procedures/mt [Methods] MH - Treatment Outcome MH - Urinary Bladder Neoplasms/pa [Pathology] MH - *Urinary Bladder Neoplasms/su [Surgery] MH - Urinary Diversion/is [Instrumentation] MH - Urinary Diversion/mt [Methods] KW - Bladder cancer; Complications; Cystectomy; Lymph node dissection; Quality of life; Randomized controlled trial; Robot assisted; Robotic; Urinary diversion AB - BACKGROUND: Open radical cystectomy (ORC) and urinary diversion in patients with bladder cancer (BCa) are associated with significant perioperative complication risk. AB - OBJECTIVE: To compare perioperative complications between robot-assisted radical cystectomy (RARC) and ORC techniques. AB - DESIGN, SETTING, AND PARTICIPANTS: A prospective randomized controlled trial was conducted during 2010 and 2013 in BCa patients scheduled for definitive treatment by radical cystectomy (RC), pelvic lymph node dissection (PLND), and urinary diversion. Patients were randomized to ORC/PLND or RARC/PLND, both with open urinary diversion. Patients were followed for 90 d postoperatively. AB - INTERVENTION: Standard ORC or RARC with PLND; all urinary diversions were performed via an open approach. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Primary outcomes were overall 90-d grade 2-5 complications defined by a modified Clavien system. Secondary outcomes included comparison of high-grade complications, estimated blood loss, operative time, pathologic outcomes, 3- and 6-mo patient-reported quality-of-life (QOL) outcomes, and total operative room and inpatient costs. Differences in binary outcomes were assessed with the chi-square test, with differences in continuous outcomes assessed by analysis of covariance with randomization group as covariate and, for QOL end points, baseline score. AB - RESULTS AND LIMITATIONS: The trial enrolled 124 patients, of whom 118 were randomized and underwent RC/PLND. Sixty were randomized to RARC and 58 to ORC. At 90 d, grade 2-5 complications were observed in 62% and 66% of RARC and ORC patients, respectively (95% confidence interval for difference, -21% to -13%; p=0.7). The similar rates of grade 2-5 complications at our mandated interim analysis met futility criteria; thus, early closure of the trial occurred. The RARC group had lower mean intraoperative blood loss (p=0.027) but significantly longer operative time than the ORC group (p<0.001). Pathologic variables including positive surgical margins and lymph node yields were similar. Mean hospital stay was 8 d in both arms (standard deviation, 3 and 5 d, respectively; p=0.5). Three- and 6-mo QOL outcomes were similar between arms. Cost analysis demonstrated an advantage to ORC compared with RARC. A limitation is the setting at a single high-volume, referral center; our findings may not be generalizable to all settings. AB - CONCLUSIONS: This trial failed to identify a large advantage for robot-assisted techniques over standard open surgery for patients undergoing RC/PLND and urinary diversion. Similar 90-d complication rates, hospital stay, pathologic outcomes, and 3- and 6-mo QOL outcomes were observed regardless of surgical technique. AB - PATIENT SUMMARY: Of 118 patients with bladder cancer who underwent radical cystectomy, pelvic lymph node dissection, and urinary diversion, half were randomized to open surgery and half to robot-assisted laparoscopic surgery. We compared the rate of complications within 90 d after surgery for the open group versus the robotic group and found no significant difference between the two groups. AB - TRIAL REGISTRATION: ClinicalTrials.gov identifier NCT01076387, www.clinicaltrials.gov. AB - Copyright © 2014 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(14)01235-4 DO - https://dx.doi.org/10.1016/j.eururo.2014.11.043 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 25496767 [pubmed] ID - S0302-2838(14)01235-4 [pii] ID - 10.1016/j.eururo.2014.11.043 [doi] ID - PMC4424172 [pmc] ID - NIHMS656563 [mid] PP - ppublish PH - 2014/09/26 [received] PH - 2014/11/21 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01076387 SL - https://clinicaltrials.gov/search/term=NCT01076387 GI - No: P30 CA008748 Organization: (CA) *NCI NIH HHS* Country: United States No: T32 CA082088 Organization: (CA) *NCI NIH HHS* Country: United States LG - English EP - 20141208 DP - 2015 Jun DC - 20150506 EZ - 2014/12/16 06:00 DA - 2016/04/08 06:00 DT - 2014/12/17 06:00 YR - 2015 ED - 20160407 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=25496767 <112. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25783405 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Cundy TP AU - Gattas NE AU - White AD AU - Najmaldin AS FA - Cundy, Thomas P FA - Gattas, Nicholas E FA - White, Alan D FA - Najmaldin, Azad S IN - Cundy, Thomas P. Department of Pediatric Surgery, Leeds General Infirmary, Leeds, United Kingdom; The Hamlyn Centre, Institute of Global Health Innovation, Imperial College London, London,United Kingdom. Electronic address: t.cundy@imperial.ac.uk. IN - Gattas, Nicholas E. Department of Pediatric Surgery, Leeds General Infirmary, Leeds, United Kingdom. IN - White, Alan D. Department of Pediatric Surgery, Leeds General Infirmary, Leeds, United Kingdom. IN - Najmaldin, Azad S. Department of Pediatric Surgery, Leeds General Infirmary, Leeds, United Kingdom. TI - Learning curve evaluation using cumulative summation analysis-a clinical example of pediatric robot-assisted laparoscopic pyeloplasty. SO - Journal of Pediatric Surgery. 50(8):1368-73, 2015 Aug AS - J Pediatr Surg. 50(8):1368-73, 2015 Aug NJ - Journal of pediatric surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - jmj, 0052631 IO - J. Pediatr. Surg. SB - Index Medicus CP - United States MH - Adolescent MH - Child MH - Child, Preschool MH - Female MH - Follow-Up Studies MH - Humans MH - *Hydronephrosis/cn [Congenital] MH - Hydronephrosis/su [Surgery] MH - Infant MH - Infant, Newborn MH - *Kidney Pelvis/su [Surgery] MH - *Laparoscopy/mt [Methods] MH - Laparoscopy/px [Psychology] MH - *Learning Curve MH - Male MH - *Models, Statistical MH - *Multicystic Dysplastic Kidney/su [Surgery] MH - Operative Time MH - Outcome Assessment (Health Care) MH - Postoperative Complications MH - Prospective Studies MH - *Robotic Surgical Procedures/mt [Methods] MH - Robotic Surgical Procedures/px [Psychology] MH - *Ureteral Obstruction/su [Surgery] MH - *Urologic Surgical Procedures/mt [Methods] MH - Urologic Surgical Procedures/px [Psychology] KW - CUSUM; Cumulative sum; Learning curve; Pediatric; Pyeloplasty; Robot-assisted AB - BACKGROUND: The cumulative summation (CUSUM) method for learning curve analysis remains under-utilized in the surgical literature in general, and is described in only a small number of publications within the field of pediatric surgery. This study introduces the CUSUM analysis technique and applies it to evaluate the learning curve for pediatric robot-assisted laparoscopic pyeloplasty (RP). AB - METHODS: Clinical data were prospectively recorded for consecutive pediatric RP cases performed by a single-surgeon. CUSUM charts and tests were generated for set-up time, docking time, console time, operating time, total operating room time, and postoperative complications. Conversions and avoidable operating room delay were separately evaluated with respect to case experience. Comparisons between case experience and time-based outcomes were assessed using the Student's t-test and ANOVA for bi-phasic and multi-phasic learning curves respectively. Comparison between case experience and complication frequency was assessed using the Kruskal-Wallis test. AB - RESULTS: A total of 90 RP cases were evaluated. The learning curve transitioned beyond the learning phase at cases 10, 15, 42, 57, and 58 for set-up time, docking time, console time, operating time, and total operating room time respectively. All comparisons of mean operating times between the learning phase and subsequent phases were statistically significant (P=<0.001-0.01). No significant difference was observed between case experience and frequency of post-operative complications (P=0.125), although the CUSUM chart demonstrated a directional change in slope for the last 12 cases in which there were high proportions of re-do cases and patients <6 months of age. AB - CONCLUSIONS: The CUSUM method has a valuable role for learning curve evaluation and outcome quality monitoring. In applying this statistical technique to the largest reported single surgeon series of pediatric RP, we demonstrate numerous distinctly shaped learning curves and well-defined learning phase transition points. AB - Copyright © 2015 Elsevier Inc. All rights reserved. RS - Multicystic renal dysplasia, bilateral ES - 1531-5037 IL - 0022-3468 DI - S0022-3468(15)00005-6 DO - https://dx.doi.org/10.1016/j.jpedsurg.2014.12.025 PT - Clinical Trial PT - Journal Article ID - 25783405 [pubmed] ID - S0022-3468(15)00005-6 [pii] ID - 10.1016/j.jpedsurg.2014.12.025 [doi] PP - ppublish PH - 2014/09/18 [received] PH - 2014/10/22 [revised] PH - 2014/12/28 [accepted] LG - English EP - 20150108 DP - 2015 Aug DC - 20150824 EZ - 2015/03/19 06:00 DA - 2016/04/07 06:00 DT - 2015/03/19 06:00 YR - 2015 ED - 20160406 RD - 20150824 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25783405 <113. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26489972 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bezerra HG AU - Mehanna E AU - W Vetrovec G AU - A Costa M AU - Weisz G FA - Bezerra, Hiram G FA - Mehanna, Emile FA - W Vetrovec, George FA - A Costa, Marco FA - Weisz, Giora IN - Bezerra, Hiram G. Harrington Heart and Vascular Institute, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio. IN - Mehanna, Emile. Harrington Heart and Vascular Institute, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio. IN - W Vetrovec, George. Division of Cardiology, VCU Pauley Heart Center, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia. IN - A Costa, Marco. Harrington Heart and Vascular Institute, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio. IN - Weisz, Giora. The Els and Charles Bendheim Department of Cardiology, Shaare Zedek Medical Center, Jerusalem, Israel. IN - Weisz, Giora. Center for Interventional Vascular Therapy, New York Presbyterian Hospital, Columbia University Medical Center, New York City, New York. TI - Longitudinal Geographic Miss (LGM) in Robotic Assisted Versus Manual Percutaneous Coronary Interventions. SO - Journal of Interventional Cardiology. 28(5):449-55, 2015 Oct AS - J. INTERVENT. CARDIOL.. 28(5):449-55, 2015 Oct NJ - Journal of interventional cardiology PI - Journal available in: Print PI - Citation processed from: Internet JC - 8907826 IO - J Interv Cardiol SB - Index Medicus CP - United States MH - Aged MH - Comparative Effectiveness Research MH - Coronary Angiography/mt [Methods] MH - Coronary Angiography/sn [Statistics & Numerical Data] MH - Coronary Artery Disease/di [Diagnosis] MH - Coronary Artery Disease/su [Surgery] MH - *Coronary Artery Disease MH - Female MH - Humans MH - Incidence MH - Israel MH - Male MH - Middle Aged MH - Percutaneous Coronary Intervention/ae [Adverse Effects] MH - Percutaneous Coronary Intervention/is [Instrumentation] MH - Percutaneous Coronary Intervention/mt [Methods] MH - *Percutaneous Coronary Intervention MH - Propensity Score MH - *Prosthesis Failure/et [Etiology] MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - Robotic Surgical Procedures/mt [Methods] MH - *Robotic Surgical Procedures MH - Robotics MH - *Stents/ae [Adverse Effects] MH - Treatment Outcome MH - United States AB - OBJECTIVES: To evaluate the impact of robotic-assisted percutaneous coronary intervention (RA-PCI) versus manual PCI (M-PCI) on the incidence of Longitudinal Geographic Miss (LGM). AB - BACKGROUND: The safety and feasibility of RA-PCI has been established in preclinical animal trials and human clinical trials. Patients with LGM have been shown to have worse clinical outcomes including significantly increased incidences of MACE. AB - METHODS: Patients with significant coronary artery disease underwent RA-PCI in the PRECISE study (n=164) and standard M-PCI in the STLLR trial (n=1,509). Longitudinal geographic miss was defined as cases where the entire length of the injured or stenotic segment was not fully covered by the total length of the stent. The incidence of LGM was compared between RA-PCI and M-PCI cohorts. AB - RESULTS: The RA-PCI cohort had a significantly greater prevalence of previous MI, previous coronary revascularization, and unstable angina. The robotic cohort exhibited a lower incidence of LGM when compared to the M-PCI patients, 12.2% to 43.1%, respectively (P<0.0001). To account for the differences in baseline characteristics between the two studies, a propensity score analysis was conducted. The propensity modeling showed similar rates of LGM in both a larger group of patients that met key PRECISE study inclusion/exclusion criteria adjusted for propensity score (9.3% vs 55.0%; P<0.0001) and in a smaller, matched on propensity score, subset of patients (10.3% vs 64.1%; P<0.0001). AB - CONCLUSION: Robotic-assisted PCI had significantly lower incidence of LGM compared to standard M-PCI. Reducing LGM potentially improves long-term clinical outcomes through reduction in MACE. AB - Copyright © 2015, Wiley Periodicals, Inc. ES - 1540-8183 IL - 0896-4327 DO - https://dx.doi.org/10.1111/joic.12231 PT - Clinical Trial PT - Journal Article PT - Multicenter Study ID - 26489972 [pubmed] ID - 10.1111/joic.12231 [doi] PP - ppublish LG - English DP - 2015 Oct DC - 20151022 EZ - 2015/10/23 06:00 DA - 2016/03/30 06:00 DT - 2015/10/23 06:00 YR - 2015 ED - 20160329 RD - 20151022 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26489972 <114. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25784166 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Wang G AU - Xiao S AU - Gao C FA - Wang, G FA - Xiao, S FA - Gao, C IN - Wang, G. PLA Institute of Cardiac Surgery, PLA General Hospital, Beijing, China. IN - Xiao, S. PLA Institute of Cardiac Surgery, PLA General Hospital, Beijing, China. IN - Gao, C. PLA Institute of Cardiac Surgery, PLA General Hospital, Beijing, China anesth301@aliyun.com. TI - The effects of cardiopulmonary bypass on pulmonary function during robotic cardiac surgery. SO - Perfusion. 30(3):213-8, 2015 Apr AS - Perfusion. 30(3):213-8, 2015 Apr NJ - Perfusion PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - bdd, 8700166 IO - Perfusion SB - Index Medicus CP - England MH - Adult MH - Aged MH - *Cardiac Surgical Procedures/mt [Methods] MH - *Cardiopulmonary Bypass/mt [Methods] MH - Coronary Artery Bypass, Off-Pump/mt [Methods] MH - Female MH - Humans MH - *Lung/pp [Physiopathology] MH - Male MH - Middle Aged MH - *One-Lung Ventilation/mt [Methods] MH - *Pneumothorax, Artificial/mt [Methods] MH - Respiratory Function Tests MH - *Robotic Surgical Procedures/mt [Methods] KW - anesthesia; cardiopulmonary bypass; one-lung ventilation; pulmonary function; robotic cardiac surgery AB - BACKGROUND: We aimed to investigate the effects of cardiopulmonary bypass (CPB) on pulmonary function under the conditions of one-lung ventilation (OLV) and carbon dioxide pneumothorax in robotic cardiac surgery. AB - METHODS: Ninety-eight patients underwent robotic cardiac surgery using the da Vinci Surgical System, including 58 on-pump surgeries and 40 off-pump surgeries. Respiratory parameters and arterial blood gases were assessed at the following time points: 25 min after the induction of anesthesia under two-lung ventilation (T1), 25 min after OLV (T2), 25 min after the termination of CPB under OLV in the on-pump group or 25 min after the main surgery intervention in the off-pump group (T3) and 20 min before the end of surgery (T4). Dynamic lung compliance (Cdyn), alveolar-arterial PO2 difference (PA-aDO2), oxygenation index (OI) and artery-alveolar O2 pressure ratio (a/A) were calculated. AB - RESULTS: No significant differences in pulmonary function parameters between T2 and T3 were observed in the off-pump group. However, in the on-pump group, compared with those at T2, PETCO2, Ppeak, PaCO2 and PA-aDO2 at T3 were higher, whereas SpO2, Cdyn, PaO2, OI and a/A were lower (p<0.05). Comparisons between the two groups at T3 indicated that SpO2, Cdyn, PaO2, OI and a/A were higher, while Ppeak, PaCO2 and PA-aDO2 were lower in the off-pump group (p<0.01). AB - CONCLUSIONS: In robotic cardiac surgery under the conditions of OLV and carbon dioxide pneumothorax, CPB worsened pulmonary function and tolerance to OLV and carbon dioxide pneumothorax. AB - Copyright © The Author(s) 2014. ES - 1477-111X IL - 0267-6591 DI - 0267659114537327 DO - https://dx.doi.org/10.1177/0267659114537327 PT - Clinical Trial PT - Journal Article ID - 25784166 [pubmed] ID - 0267659114537327 [pii] ID - 10.1177/0267659114537327 [doi] PP - ppublish LG - English EP - 20140603 DP - 2015 Apr DC - 20150318 EZ - 2015/03/19 06:00 DA - 2016/03/30 06:00 DT - 2015/03/19 06:00 YR - 2015 ED - 20160329 RD - 20150318 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25784166 <115. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26052000 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Avery DI AU - Herbst KW AU - Lendvay TS AU - Noh PH AU - Dangle P AU - Gundeti MS AU - Steele MC AU - Corbett ST AU - Peters CA AU - Kim C FA - Avery, Daniel I FA - Herbst, Katherine W FA - Lendvay, Thomas S FA - Noh, Paul H FA - Dangle, Pankaj FA - Gundeti, Mohan S FA - Steele, Matthew C FA - Corbett, Sean T FA - Peters, Craig A FA - Kim, Christina IN - Avery, Daniel I. University of Washington, Seattle, WA, USA. IN - Herbst, Katherine W. Connecticut Children's Medical Center, Hartford, CT, USA. IN - Lendvay, Thomas S. University of Washington, Seattle, WA, USA; Seattle Children's Hospital, Seattle, WA, USA. IN - Noh, Paul H. Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. IN - Dangle, Pankaj. University of Chicago Medical and Biological Sciences, Chicago, IL, USA. IN - Gundeti, Mohan S. University of Chicago Medical and Biological Sciences, Chicago, IL, USA. IN - Steele, Matthew C. University of Virginia, PO Box 800422, Charlottesville, VA, USA. IN - Corbett, Sean T. University of Virginia, PO Box 800422, Charlottesville, VA, USA. IN - Peters, Craig A. Children's National Health System, Washington, DC, USA. IN - Kim, Christina. University of Washington, Seattle, WA, USA. Electronic address: Ckim@connecticutchildrens.org. TI - Robot-assisted laparoscopic pyeloplasty: Multi-institutional experience in infants. CM - Comment in: J Pediatr Urol. 2015 Jun;11(3):140; PMID: 25783202 SO - Journal of pediatric urology. 11(3):139.e1-5, 2015 Jun AS - J Pediatr Urol. 11(3):139.e1-5, 2015 Jun NJ - Journal of pediatric urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101233150 IO - J Pediatr Urol SB - Index Medicus CP - England MH - Female MH - Humans MH - *Hydronephrosis/su [Surgery] MH - Infant MH - *Kidney Pelvis/su [Surgery] MH - *Laparoscopy MH - Length of Stay MH - Male MH - Operative Time MH - Retrospective Studies MH - *Robotic Surgical Procedures MH - Treatment Outcome MH - United States MH - *Ureteral Obstruction/su [Surgery] KW - Minimally invasive; Pyeloplasty; Robotic urologic surgical procedures; Ureteropelvic junction pediatric surgical procedures AB - INTRODUCTION: Robot-assisted laparoscopic pyeloplasty (RALP) has been gaining acceptance among pediatric urologists. Over 300 have been described in the literature, but few studies have evaluated the role of RALP in infants alone. AB - OBJECTIVE: We sought to examine the operative experience and outcomes of RALP in a cohort of infants treated at multiple institutions across the United States. Our primary aim was to describe the safety and efficacy of RALP within this cohort. We recognize the challenges of performing minimally invasive surgery in small patients. In our paper, we address some technical considerations for the infant population. AB - STUDY DESIGN: This multi-centered observational study collected data on subjects one year of age or less who underwent RALP between April 2006 and July 2012 at five institutions. The primary outcome was resolution of hydronephrosis, and secondary outcomes included surgical time and complications. AB - RESULTS: A total of 60 patients (62 procedures) underwent RALP by six surgeons during the study period. All surgeons had > 5 years of experience beyond fellowship training. Mean surgical age was 7.3 months (SD +/- 1.7 mo), 56 patients (95%) were diagnosed prenatally, and 59 patients (95%) had follow up imaging. Of these patients, 91% showed resolution or improvement of hydronephrosis. Two patients had recurrent obstruction and required additional surgery. Mean surgical time was 3 hours 52 minutes (SD +/- 43 minutes). Seven (11%) patients reported intra-operative or immediate post-operative complications. AB - DISCUSSION: This series found a 91% success rate for reduction or resolution of hydronephrosis, and an 11% complication rate. This is equivalent to modern series comparing open pyeloplasty to pure laparoscopic and robotic-assisted laparoscopic pyeloplasty, which report success rates ranging from 70-96%, and complication rates ranging from 0-24% for open pyeloplasty. We lacked a standardized technique amongst institutions. This was not surprising since there are not established technical benchmarks for this surgery. However, we specified multiple technical considerations for this unique patient population. AB - CONCLUSION: The advantages of using robot-assistance to perform pyeloplasty in infants remain to be defined. This study cannot make that assessment due to small sample size. Nonetheless, this cohort is the largest robotic pyeloplasty series in infants to date. Seeing an excellent success rate and a low complication rate in this infant cohort is encouraging. AB - Copyright © 2015 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved. ES - 1873-4898 IL - 1477-5131 DI - S1477-5131(15)00080-7 DO - https://dx.doi.org/10.1016/j.jpurol.2014.11.025 PT - Journal Article PT - Multicenter Study PT - Observational Study ID - 26052000 [pubmed] ID - S1477-5131(15)00080-7 [pii] ID - 10.1016/j.jpurol.2014.11.025 [doi] PP - ppublish PH - 2014/07/22 [received] PH - 2014/11/11 [accepted] LG - English EP - 20150312 DP - 2015 Jun DC - 20150620 EZ - 2015/06/09 06:00 DA - 2016/03/29 06:00 DT - 2015/06/09 06:00 YR - 2015 ED - 20160328 RD - 20150620 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26052000 <116. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27011458 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - PubMed-not-MEDLINE AU - Somashekhar SP AU - Ashwin KR AU - Rajashekhar J AU - Zaveri S FA - Somashekhar, S P FA - Ashwin, K R FA - Rajashekhar, Jaka FA - Zaveri, Shabber IN - Somashekhar, S P. Department of Surgical Oncology, Manipal Comprehensive Cancer Centre, Manipal Hospital, # 98 HAL Airport Road, Bangalore, 560017 India. IN - Ashwin, K R. No. 8, Second Anjaneya Temple Street, Seshadripurum, Bangalore, 560020 India. IN - Rajashekhar, Jaka. Department of Surgical Oncology, Manipal Comprehensive Cancer Centre, Manipal Hospital, # 98 HAL Airport Road, Bangalore, 560017 India. IN - Zaveri, Shabber. Department of Surgical Oncology, Manipal Comprehensive Cancer Centre, Manipal Hospital, # 98 HAL Airport Road, Bangalore, 560017 India. TI - Prospective Randomized Study Comparing Robotic-Assisted Surgery with Traditional Laparotomy for Rectal Cancer-Indian Study. SO - Indian Journal of Surgery. 77(Suppl 3):788-94, 2015 Dec AS - Indian J Surg. 77(Suppl 3):788-94, 2015 Dec NJ - The Indian journal of surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Print JC - 0373026 IO - Indian J Surg PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775566 CP - India KW - India; Minimally invasive surgery; Rectal cancer; Robotic surgery AB - Rectal cancer is one of the common cancers in India. Surgical management is the mainstay of initial treatment for majority of patients. Minimally invasive surgery has gained acceptance for the surgical treatment of rectal cancer because, compared with laparotomy, it is associated with fewer complications, shorter hospitalization, and faster recovery. The aim of this study is to evaluate the safety, feasibility, technique, and outcomes (postoperative, oncological, and functional) of robotic-assisted rectal surgery in comparison with open surgery in the Indian population. A prospective randomized study was undertaken from August 2011 to December 2012. Fifty patients who presented with rectal carcinoma were randomized to either robotic arm (RA) or open arm (OA) group. Both groups were matched for clinical stage and operation type. Technique and feasibility of robotic-assisted surgery in terms of operating time, estimated blood loss, margins status, total number of lymph nodes retrieved, hospital stay, conversion to open procedure, complications, and functional outcomes were analyzed. The mean operative time was significantly longer in the RA than in the OA group (310 vs 246 min, P<0.001) but was significantly reduced in the latter part of the robotic-assisted patients compared with the initial patients. The mean estimated blood loss was significantly less in the RA compared with the OA group (165.14 vs 406.04 ml, P<0.001). None of the patients had margin positivity. The mean distal resection margin was significantly longer in the RA than in the OA group (3.6 vs 2.4 cm, P<0.001). A total of 100 % of patients in the RA group had complete mesorectal excision while two patients in the OA group had incomplete mesorectal excision. The average number of retrieved lymph nodes was adequate for accurate staging. The number of lymph nodes removed by robotic method is slightly higher than the open method (16.88 vs 15.20) but with no statistical significance. Conversion rate was nil. The mean hospital stay was significantly shorter in the RA group (7.52 vs 13.24 days, P<0.001). Postoperative and functional outcomes were comparable between the two groups. Robotic-assisted surgery is an emerging technique in our country. Robotic-assisted rectal cancer surgery is safe with low conversion rates and acceptable morbidity and is oncologically feasible. IS - 0972-2068 IL - 0973-9793 DI - 1003 DO - https://dx.doi.org/10.1007/s12262-013-1003-4 PT - Journal Article ID - 27011458 [pubmed] ID - 10.1007/s12262-013-1003-4 [doi] ID - 1003 [pii] ID - PMC4775566 [pmc] PP - ppublish PH - 2013/02/21 [received] PH - 2013/10/27 [accepted] LG - English EP - 20131111 DP - 2015 Dec DC - 20160325 EZ - 2016/03/25 06:00 DA - 2016/03/25 06:01 DT - 2016/03/25 06:00 YR - 2015 ED - 20160325 RD - 20161201 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27011458 <117. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27000922 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - PubMed-not-MEDLINE AU - Wechter ME AU - Kho RM AU - Chen AH AU - Magrina JF AU - Pettit PD FA - Wechter, Mary Ellen FA - Kho, Rosanne M FA - Chen, Anita H FA - Magrina, Javier F FA - Pettit, Paul D IN - Wechter, Mary Ellen. North Florida OBGYN Division 1, Baptist Medical Center Downtown, 836 Prudential Dr., Suite 1600, Jacksonville, FL, 32207, USA. mwechter@nfobgyn.com. IN - Wechter, Mary Ellen. Department of Gynecology, Mayo Clinic Florida, Jacksonville, FL, USA. mwechter@nfobgyn.com. IN - Kho, Rosanne M. Department of Gynecology, Mayo Clinic Arizona, Scottsdale, AZ, USA. IN - Chen, Anita H. Department of Gynecology, Mayo Clinic Florida, Jacksonville, FL, USA. IN - Magrina, Javier F. Department of Gynecology, Mayo Clinic Arizona, Scottsdale, AZ, USA. IN - Pettit, Paul D. Department of Gynecology, Mayo Clinic Florida, Jacksonville, FL, USA. TI - Preventing slide in Trendelenburg position: randomized trial comparing foam and gel pads. SO - Journal of Robotic Surgery. 7(3):267-71, 2013 Sep AS - J. robot. surg.. 7(3):267-71, 2013 Sep NJ - Journal of robotic surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Print JC - 101300401 IO - J Robot Surg CP - England KW - Positioning; Robotics; Safety; Surgical complications; Trendelenburg AB - To compare patient slide in Trendelenburg position using egg-crate foam or gel pad. This randomized trial compared slide on friction pads during Trendelenburg position for robotic and laparoscopic gynecologic procedures in 61 patients at the Mayo Clinic Florida between March 11, 2010 and May 31, 2011. Data was analyzed using Student's t test with significance defined as p < 0.05. There was no significant difference in mean slide according to pad type (foam 3.0 +/- SD 2.1 cm; gel 4.5 +/- SD 4.0 cm, p = 0.08). Minor complaints occurred in 10 % of patients, and did not differ by group (p = 0.4). Most complaints (98 %) were transient shoulder or neck pain. A single patient had both transient right hand numbness and right lateral thigh paresthesia. We assessed outcomes by chart review from the inpatient care and postoperative evaluation notes (mean 44 +/- SD 17 days), and by review of any intervening notes that occurred before the study's end (mean 345 +/- SD 116 days). Trendelenburg-related slide is equivalent on either egg-crate foam or gel pad. IS - 1863-2483 IL - 1863-2483 DI - 10.1007/s11701-012-0370-3 DO - https://dx.doi.org/10.1007/s11701-012-0370-3 PT - Journal Article ID - 27000922 [pubmed] ID - 10.1007/s11701-012-0370-3 [doi] ID - 10.1007/s11701-012-0370-3 [pii] PP - ppublish PH - 2012/05/03 [received] PH - 2012/07/01 [accepted] LG - English EP - 20121206 DP - 2013 Sep DC - 20160322 EZ - 2016/03/23 06:00 DA - 2013/09/01 00:01 DT - 2013/09/01 00:00 YR - 2013 ED - 20160323 RD - 20160322 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27000922 <118. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25848192 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ryan CE AU - Ross SB AU - Sukharamwala PB AU - Sadowitz BD AU - Wood TW AU - Rosemurgy AS FA - Ryan, Carrie E FA - Ross, Sharona B FA - Sukharamwala, Prashant B FA - Sadowitz, Benjamin D FA - Wood, Thomas W FA - Rosemurgy, Alexander S IN - Ryan, Carrie E. Florida Hospital Tampa. IN - Ross, Sharona B. Florida Hospital Tampa. IN - Sukharamwala, Prashant B. Florida Hospital Tampa. IN - Sadowitz, Benjamin D. Florida Hospital Tampa. IN - Wood, Thomas W. Florida Hospital Tampa. IN - Rosemurgy, Alexander S. Florida Hospital Tampa. TI - Distal pancreatectomy and splenectomy: a robotic or LESS approach. SO - Journal of the Society of Laparoendoscopic Surgeons. 19(1):e2014.00246, 2015 Jan-Mar AS - J Soc Laparoendosc Surg. 19(1):e2014.00246, 2015 Jan-Mar NJ - JSLS : Journal of the Society of Laparoendoscopic Surgeons PI - Journal available in: Print PI - Citation processed from: Internet JC - 100884618, c8o IO - JSLS PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379862 SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Blood Loss, Surgical/sn [Statistics & Numerical Data] MH - Conversion to Open Surgery/sn [Statistics & Numerical Data] MH - Female MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - Operative Time MH - Outcome Assessment (Health Care) MH - *Pancreatectomy/mt [Methods] MH - Pancreatic Neoplasms/su [Surgery] MH - Prospective Studies MH - *Robotic Surgical Procedures/mt [Methods] MH - *Splenectomy/mt [Methods] KW - Laparoendoscopic single-site surgery; Laparoscopic distal pancreatectomy; Robotic distal pancreatectomy and splenectomy AB - INTRODUCTION: The role and application of robotic surgery are debated, particularly given the expansion of laparoscopy, especially laparoendoscopic single-site (LESS) surgery. This cohort study was undertaken to delineate differences in outcomes between LESS and robotic distal pancreatectomy and splenectomy. AB - METHODS: With Institutional Review Board approval, patients undergoing LESS or robotic distal pancreatectomy and splenectomy from September 1, 2012, through December 31, 2014, were prospectively observed, and data were collected. The results are expressed as the median, with the mean +/- SD. AB - RESULTS: Thirty-four patients underwent a minimally invasive distal pancreatectomy and splenectomy: 18 with robotic and 16 with LESS surgery. The patients were similar in sex, age, and body mass index. Conversions to open surgery and estimated blood loss were similar. There were two intraoperative complications in the group that underwent the robotic approach. Time spent in the operating room was significantly longer with the robot (297 vs 254 minutes, P = .03), although operative duration (i.e., incision to closure) was not longer (225 vs 190 minutes; P = .15). Of the operations studied, 79% were undertaken for neoplastic processes. Tumor size was 3.5 cm for both approaches; R0 resections were achieved in all patients. Length of stay was similar in the two study groups (5 vs 4 days). There was one 30-day readmission after robotic surgery. AB - CONCLUSIONS: Patient outcomes are similar with LESS or robotic distal pancreatectomy and splenectomy. Robotic operations require more time in the operating room. Both are safe and efficacious minimally invasive operations that follow similar oncologic principles for similar tumors, and both should be in the surgeon's armamentarium for distal pancreatectomy and splenectomy. ES - 1938-3797 IL - 1086-8089 DI - e2014.00246 DI - JSLS.2014.00246 DO - https://dx.doi.org/10.4293/JSLS.2014.00246 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 25848192 [pubmed] ID - 10.4293/JSLS.2014.00246 [doi] ID - JSLS.2014.00246 [pii] ID - PMC4379862 [pmc] PP - ppublish LG - English DP - 2015 Jan-Mar DC - 20150407 EZ - 2015/04/08 06:00 DA - 2016/03/18 06:00 DT - 2015/04/08 06:00 YR - 2015 ED - 20160317 RD - 20161020 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25848192 <119. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25484140 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Autorino R AU - Zargar H AU - Mariano MB AU - Sanchez-Salas R AU - Sotelo RJ AU - Chlosta PL AU - Castillo O AU - Matei DV AU - Celia A AU - Koc G AU - Vora A AU - Aron M AU - Parsons JK AU - Pini G AU - Jensen JC AU - Sutherland D AU - Cathelineau X AU - Nunez Bragayrac LA AU - Varkarakis IM AU - Amparore D AU - Ferro M AU - Gallo G AU - Volpe A AU - Vuruskan H AU - Bandi G AU - Hwang J AU - Nething J AU - Muruve N AU - Chopra S AU - Patel ND AU - Derweesh I AU - Champ Weeks D AU - Spier R AU - Kowalczyk K AU - Lynch J AU - Harbin A AU - Verghese M AU - Samavedi S AU - Molina WR AU - Dias E AU - Ahallal Y AU - Laydner H AU - Cherullo E AU - De Cobelli O AU - Thiel DD AU - Lagerkvist M AU - Haber GP AU - Kaouk J AU - Kim FJ AU - Lima E AU - Patel V AU - White W AU - Mottrie A AU - Porpiglia F FA - Autorino, Riccardo FA - Zargar, Homayoun FA - Mariano, Mirandolino B FA - Sanchez-Salas, Rafael FA - Sotelo, Rene J FA - Chlosta, Piotr L FA - Castillo, Octavio FA - Matei, Deliu V FA - Celia, Antonio FA - Koc, Gokhan FA - Vora, Anup FA - Aron, Monish FA - Parsons, J Kellogg FA - Pini, Giovannalberto FA - Jensen, James C FA - Sutherland, Douglas FA - Cathelineau, Xavier FA - Nunez Bragayrac, Luciano A FA - Varkarakis, Ioannis M FA - Amparore, Daniele FA - Ferro, Matteo FA - Gallo, Gaetano FA - Volpe, Alessandro FA - Vuruskan, Hakan FA - Bandi, Gaurav FA - Hwang, Jonathan FA - Nething, Josh FA - Muruve, Nic FA - Chopra, Sameer FA - Patel, Nishant D FA - Derweesh, Ithaar FA - Champ Weeks, David FA - Spier, Ryan FA - Kowalczyk, Keith FA - Lynch, John FA - Harbin, Andrew FA - Verghese, Mohan FA - Samavedi, Srinivas FA - Molina, Wilson R FA - Dias, Emanuel FA - Ahallal, Youness FA - Laydner, Humberto FA - Cherullo, Edward FA - De Cobelli, Ottavio FA - Thiel, David D FA - Lagerkvist, Mikael FA - Haber, Georges-Pascal FA - Kaouk, Jihad FA - Kim, Fernando J FA - Lima, Estevao FA - Patel, Vipul FA - White, Wesley FA - Mottrie, Alexander FA - Porpiglia, Francesco IN - Autorino, Riccardo. University Hospitals Urology Institute, Cleveland, OH, USA. Electronic address: ricautor@gmail.com. IN - Zargar, Homayoun. Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA. IN - Mariano, Mirandolino B. Section of Urology, Santa Casa de Misericordia de Porto Alegre, Rio Grande do Sul, Brazil. IN - Sanchez-Salas, Rafael. Department of Urology, Institut Montsouris, Paris, France. IN - Sotelo, Rene J. Department of Urology, La Floresta Medical Institute, Caracas, Venezuela. IN - Chlosta, Piotr L. Department of Urology, Collegium Medicum, Jagiellonian University, Cracow, Poland. IN - Castillo, Octavio. Department of Urology, Clinica Indisa, Universidad Andres Bello, Santiago, Chile. IN - Matei, Deliu V. Division of Urology, European Institute of Oncology, Milan, Italy. IN - Celia, Antonio. Department of Urology, San Bassiano Hospital, Bassano del Grappa, Italy. IN - Koc, Gokhan. Department of Urology, Tepecik Teaching and Research Hospital, Izmir, Turkey. IN - Vora, Anup. Department of Urology, Cleveland Clinic Florida, Weston, FL, USA. IN - Aron, Monish. Department of Urology, University of Southern California, Los Angeles, CA, USA. IN - Parsons, J Kellogg. Department of Urology, University of California San Diego Health System, San Diego, CA, USA. IN - Pini, Giovannalberto. Uroclinic AB Robotic Surgery, Stockholm, Sweden. IN - Jensen, James C. Department of Surgery/Urology, Marshall University, Huntington, WV, USA. IN - Sutherland, Douglas. Department of Urology, MultiCare Health System Tacoma, Tacoma, WA, USA. IN - Cathelineau, Xavier. Department of Urology, Institut Montsouris, Paris, France. IN - Nunez Bragayrac, Luciano A. Department of Urology, La Floresta Medical Institute, Caracas, Venezuela. IN - Varkarakis, Ioannis M. Department of Urology, Collegium Medicum, Jagiellonian University, Cracow, Poland. IN - Amparore, Daniele. Department of Urology, University of Turin, San Luigi Gonzaga Hospital, Orbassano, Italy; Department of Urology, O.L.V. Clinic, Aalst, Belgium. IN - Ferro, Matteo. Division of Urology, European Institute of Oncology, Milan, Italy. IN - Gallo, Gaetano. Department of Urology, San Bassiano Hospital, Bassano del Grappa, Italy. IN - Volpe, Alessandro. Department of Urology, O.L.V. Clinic, Aalst, Belgium; Division of Urology, University of Eastern Piedmont, Maggiore della Carita Hospital, Novara, Italy. IN - Vuruskan, Hakan. Department of Urology, Faculty of Medicine, Uludag University, Bursa, Turkey. IN - Bandi, Gaurav. Department of Urology, Georgetown University, Washington, DC, USA. IN - Hwang, Jonathan. Department of Urology, Washington Hospital Center, Washington, DC, USA. IN - Nething, Josh. Department of Urology, Cleveland Clinic Florida, Weston, FL, USA. IN - Muruve, Nic. Department of Urology, Cleveland Clinic Florida, Weston, FL, USA. IN - Chopra, Sameer. Department of Urology, University of Southern California, Los Angeles, CA, USA. IN - Patel, Nishant D. Department of Urology, University of California San Diego Health System, San Diego, CA, USA. IN - Derweesh, Ithaar. Department of Urology, University of California San Diego Health System, San Diego, CA, USA. IN - Champ Weeks, David. Department of Urology, MultiCare Health System Tacoma, Tacoma, WA, USA. IN - Spier, Ryan. Department of Urology, MultiCare Health System Tacoma, Tacoma, WA, USA. IN - Kowalczyk, Keith. Department of Urology, Georgetown University, Washington, DC, USA. IN - Lynch, John. Department of Urology, Georgetown University, Washington, DC, USA. IN - Harbin, Andrew. Department of Urology, Washington Hospital Center, Washington, DC, USA. IN - Verghese, Mohan. Department of Urology, Washington Hospital Center, Washington, DC, USA. IN - Samavedi, Srinivas. Department of Urology, Global Robotics Institute Orlando, Orlando, FL, USA. IN - Molina, Wilson R. Department of Urology, Denver Health Medical Center, Denver, CO, USA. IN - Dias, Emanuel. Department of Urology, Braga Hospital, Braga, Portugal. IN - Ahallal, Youness. Department of Urology, Institut Montsouris, Paris, France. IN - Laydner, Humberto. University Hospitals Urology Institute, Cleveland, OH, USA. IN - Cherullo, Edward. University Hospitals Urology Institute, Cleveland, OH, USA. IN - De Cobelli, Ottavio. Division of Urology, European Institute of Oncology, Milan, Italy. IN - Thiel, David D. Department of Urology, Mayo Clinic, Jacksonville, FL, USA. IN - Lagerkvist, Mikael. Uroclinic AB Robotic Surgery, Stockholm, Sweden. IN - Haber, Georges-Pascal. Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA. IN - Kaouk, Jihad. Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA. IN - Kim, Fernando J. Department of Urology, Denver Health Medical Center, Denver, CO, USA. IN - Lima, Estevao. Department of Urology, Braga Hospital, Braga, Portugal. IN - Patel, Vipul. Department of Urology, Global Robotics Institute Orlando, Orlando, FL, USA. IN - White, Wesley. Division of Urologic Surgery, University of Tennessee, Knoxville, Knoxville, TN, USA. IN - Mottrie, Alexander. Department of Urology, O.L.V. Clinic, Aalst, Belgium. IN - Porpiglia, Francesco. Department of Urology, University of Turin, San Luigi Gonzaga Hospital, Orbassano, Italy. TI - Perioperative Outcomes of Robotic and Laparoscopic Simple Prostatectomy: A European-American Multi-institutional Analysis. CM - Comment in: Eur Urol. 2015 Jul;68(1):e7-8; PMID: 25660079 CM - Comment in: Eur Urol. 2015 Jul;68(1):95-6; PMID: 25544633 SO - European Urology. 68(1):86-94, 2015 Jul AS - Eur Urol. 68(1):86-94, 2015 Jul NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - *Adenocarcinoma/su [Surgery] MH - *Adenoma/su [Surgery] MH - Aged MH - Cohort Studies MH - Europe/ep [Epidemiology] MH - Humans MH - Laparoscopy MH - Male MH - Middle Aged MH - Organ Size MH - *Postoperative Complications/ep [Epidemiology] MH - Prostate/pa [Pathology] MH - *Prostate/su [Surgery] MH - Prostatectomy MH - Prostatic Hyperplasia/co [Complications] MH - *Prostatic Hyperplasia/su [Surgery] MH - *Prostatic Neoplasms/su [Surgery] MH - Retrospective Studies MH - Robotic Surgical Procedures MH - United States/ep [Epidemiology] MH - Urinary Bladder Neck Obstruction/et [Etiology] MH - *Urinary Bladder Neck Obstruction/su [Surgery] KW - Benign prostatic hyperplasia; Laparoscopy; Outcomes; Robotic surgery; Simple prostatectomy AB - BACKGROUND: Laparoscopic and robotic simple prostatectomy (SP) have been introduced with the aim of reducing the morbidity of the standard open technique. AB - OBJECTIVE: To report a large multi-institutional series of minimally invasive SP (MISP). AB - DESIGN, SETTING, AND PARTICIPANTS: Consecutive cases of MISP done for the treatment of bladder outlet obstruction (BOO) due to benign prostatic enlargement (BPE) between 2000 and 2014 at 23 participating institutions in the Americas and Europe were included in this retrospective analysis. AB - INTERVENTION: Laparoscopic or robotic SP. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Demographic data and main perioperative outcomes were gathered and analyzed. A multivariable analysis was conducted to identify factors associated with a favorable trifecta outcome, arbitrarily defined as a combination of the following postoperative events: International Prostate Symptom Score <8, maximum flow rate >15ml/s, and no perioperative complications. AB - RESULTS AND LIMITATIONS: Overall, 1330 consecutive cases were analyzed, including 487 robotic (36.6%) and 843 laparoscopic (63.4%) SP cases. Median overall prostate volume was 100ml (range: 89-128). Median estimated blood loss was 200ml (range: 150-300). An intraoperative transfusion was required in 3.5% of cases, an intraoperative complication was recorded in 2.2% of cases, and the conversion rate was 3%. Median length of stay was 4 d (range: 3-5). On pathology, prostate cancer was found in 4% of cases. Overall postoperative complication rate was 10.6%, mostly of low grade. At a median follow-up of 12 mo, a significant improvement was observed for subjective and objective indicators of BOO. Trifecta outcome was not significantly influenced by the type of procedure (robotic vs laparoscopic; p=0.136; odds ratio [OR]: 1.6; 95% confidence interval [CI], 0.8-2.9), whereas operative time (p=0.01; OR: 0.9; 95% CI, 0.9-1.0) and estimated blood loss (p=0.03; OR: 0.9; 95% CI, 0.9-1.0) were the only two significant factors. Retrospective study design, lack of a control arm, and limited follow-up represent major limitations of the present analysis. AB - CONCLUSIONS: This study provides the largest outcome analysis reported for MISP for BOO/BPE. These findings confirm that SP can be safely and effectively performed in a minimally invasive fashion in a variety of healthcare settings in which specific surgical expertise and technology is available. MISP can be considered a viable surgical treatment in cases of large prostatic adenomas. The use of robotic technology for this indication can be considered in centers that have a robotic program in place for other urologic indications. AB - PATIENT SUMMARY: Analysis of a large data set from multiple institutions shows that surgical removal of symptomatic large prostatic adenomas can be carried out with good outcomes by using robot-assisted laparoscopy. AB - Copyright © 2014 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(14)01236-6 DO - https://dx.doi.org/10.1016/j.eururo.2014.11.044 PT - Clinical Study PT - Journal Article PT - Multicenter Study ID - 25484140 [pubmed] ID - S0302-2838(14)01236-6 [pii] ID - 10.1016/j.eururo.2014.11.044 [doi] PP - ppublish PH - 2014/09/29 [received] PH - 2014/11/21 [accepted] LG - English EP - 20141204 DP - 2015 Jul DC - 20150619 EZ - 2014/12/09 06:00 DA - 2016/03/16 06:00 DT - 2014/12/09 06:00 YR - 2015 ED - 20160315 RD - 20150619 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25484140 <120. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25687957 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hassan SO AU - Dudhia J AU - Syed LH AU - Patel K AU - Farshidpour M AU - Cunningham SC AU - Kowdley GC FA - Hassan, Syed Omar FA - Dudhia, Jaimin FA - Syed, Labiq H FA - Patel, Kalpesh FA - Farshidpour, Maham FA - Cunningham, Steven C FA - Kowdley, Gopal C IN - Hassan, Syed Omar. Department of Surgery, Saint Agnes Hospital, Baltimore, Maryland. IN - Dudhia, Jaimin. Department of Surgery, Saint Agnes Hospital, Baltimore, Maryland. IN - Syed, Labiq H. Department of Surgery, Saint Agnes Hospital, Baltimore, Maryland. IN - Patel, Kalpesh. Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland. IN - Farshidpour, Maham. Department of Surgery, Saint Agnes Hospital, Baltimore, Maryland. IN - Cunningham, Steven C. Department of Surgery, Saint Agnes Hospital, Baltimore, Maryland. IN - Kowdley, Gopal C. Department of Surgery, Saint Agnes Hospital, Baltimore, Maryland. Electronic address: gkowdley@stagnes.org. TI - Conventional Laparoscopic vs Robotic Training: Which is Better for Naive Users? A Randomized Prospective Crossover Study. SO - Journal of Surgical Education. 72(4):592-9, 2015 Jul-Aug AS - J Surg Educ. 72(4):592-9, 2015 Jul-Aug NJ - Journal of surgical education PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101303204 IO - J Surg Educ SB - Index Medicus CP - United States MH - *Clinical Competence MH - Cross-Over Studies MH - Curriculum MH - Education, Medical, Graduate MH - Education, Medical, Undergraduate MH - Educational Measurement MH - Humans MH - *Laparoscopy/ed [Education] MH - Learning Curve MH - Prospective Studies MH - *Robotics/ed [Education] MH - *Simulation Training KW - Medical Knowledge; Patient Care; Practice-Based Learning and Improvement; conventional laparoscopy; efficient; learning curve; naive; robotic training; transfer effect AB - OBJECTIVE: Robotic training (RT) using the da Vinci skills simulator and conventional training (CT) using a laparoscopic "training box" are both used to augment operative skills in minimally invasive surgery. The current study tests the hypothesis that skill acquisition is more rapid using RT than using CT among naive learners. AB - DESIGN AND PARTICIPANTS: A total of 40 subjects without laparoscopic or robotic surgical experience were enrolled and randomized to begin with either RT or CT. Then, 2 specific RT tasks were reproduced for CT and repeated 5 times each with RT and CT. Time and quality indicators were measured quantitatively. A crossover technique was used to control for in-study experience bias. AB - RESULTS: The tasks "pick and place jacks" (PP) and "thread the rings" (TR) were achieved faster with RT than with CT despite crossover (p < 0.0001). An RT-favoring difference was observed in speed for both tasks when changing modality. Percentage improvement with increasing trials was similar for RT and CT: RT completion time averaged 39 seconds and 211 seconds (PP and TR, respectively), compared with 65 seconds and 362 seconds when using CT (p < 0.0001); final improvement averaged 26% and 46% for RT (PP and TR, respectively) vs 31% and 47% for CT (p was 0.76 for PP and 0.20 for TR). Within the PP task, RT times averaged 41 seconds without previous CT experience vs 35 seconds with previous CT experience (p = 0.20); CT times averaged 61 seconds without and 69 seconds with previous RT experience (p = 0.48). Comparable times for the TR task were 212 seconds vs 216 seconds (p = 0.66) and 388 seconds vs 334 seconds (p = 0.17). Both instrument collisions and excessive force occurred more commonly for RT than for CT within the TR task (p < 0.0001). AB - CONCLUSIONS: Speeds were faster overall with RT than with CT, but the percentage of speed improvement with trials was similar, suggesting similar learning curves, with minimal transfer effect appreciated. AB - Copyright © 2015 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved. ES - 1878-7452 IL - 1878-7452 DI - S1931-7204(14)00337-7 DO - https://dx.doi.org/10.1016/j.jsurg.2014.12.008 PT - Journal Article PT - Randomized Controlled Trial ID - 25687957 [pubmed] ID - S1931-7204(14)00337-7 [pii] ID - 10.1016/j.jsurg.2014.12.008 [doi] PP - ppublish PH - 2014/10/17 [received] PH - 2014/11/18 [revised] PH - 2014/12/16 [accepted] LG - English EP - 20150214 DP - 2015 Jul-Aug DC - 20150615 EZ - 2015/02/18 06:00 DA - 2016/03/15 06:00 DT - 2015/02/18 06:00 YR - 2015 ED - 20160314 RD - 20150615 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25687957 <121. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26303347 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Almeida FA AU - Smith-Ray RL AU - Dzewaltowski DA AU - Glasgow RE AU - Lee RE AU - Thomas DS AU - Xu S AU - Estabrooks PA AI - Almeida, Fabio A; ORCID: http://orcid.org/0000-0002-2404-0694 AI - Smith-Ray, Renae L; ORCID: http://orcid.org/0000-0001-9642-7727 AI - Dzewaltowski, David A; ORCID: http://orcid.org/0000-0002-6592-1041 AI - Glasgow, Russell E; ORCID: http://orcid.org/0000-0003-4218-3231 AI - Lee, Rebecca E; ORCID: http://orcid.org/0000-0002-9011-0689 AI - Thomas, Deborah S K; ORCID: http://orcid.org/0000-0002-9594-9790 AI - Xu, Stanley; ORCID: http://orcid.org/0000-0002-4750-7672 AI - Estabrooks, Paul A; ORCID: http://orcid.org/0000-0003-2261-9886 FA - Almeida, Fabio A FA - Smith-Ray, Renae L FA - Dzewaltowski, David A FA - Glasgow, Russell E FA - Lee, Rebecca E FA - Thomas, Deborah S K FA - Xu, Stanley FA - Estabrooks, Paul A IN - Almeida, Fabio A. Implementation and Systems Science Laboratory, Department of Human, Nutrition, Foods, and Exercise, Virginia Tech, Roanoke, VA, United States. falmeida@vt.edu. TI - An Interactive Computer Session to Initiate Physical Activity in Sedentary Cardiac Patients: Randomized Controlled Trial. SO - Journal of Medical Internet Research. 17(8):e206, 2015 Aug 24 AS - J Med Internet Res. 17(8):e206, 2015 Aug 24 NJ - Journal of medical Internet research PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 100959882 IO - J. Med. Internet Res. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642390 SB - Index Medicus CP - Canada MH - Aged MH - *Cognitive Therapy MH - *Exercise MH - Exercise Test MH - Female MH - *Fitness Centers MH - *Heart Diseases/di [Diagnosis] MH - Humans MH - Internet MH - Linear Models MH - Male MH - Middle Aged MH - Motor Activity MH - *Risk Reduction Behavior MH - *Sedentary Lifestyle MH - Treatment Outcome MH - *User-Computer Interface KW - behavioral research; cardiovascular diseases; exercise, physical; human computer interaction; interactive media; treadmill test AB - BACKGROUND: Physical activity (PA) improves many facets of health. Despite this, the majority of American adults are insufficiently active. Adults who visit a physician complaining of chest pain and related cardiovascular symptoms are often referred for further testing. However, when this testing does not reveal an underlying disease or pathology, patients typically receive no additional standard care services. A PA intervention delivered within the clinic setting may be an effective strategy for improving the health of this population at a time when they may be motivated to take preventive action. AB - OBJECTIVE: Our aim was to determine the effectiveness of a tailored, computer-based, interactive personal action planning session to initiate PA among a group of sedentary cardiac patients following exercise treadmill testing (ETT). AB - METHODS: This study was part of a larger 2x2 randomized controlled trial to determine the impact of environmental and social-cognitive intervention approaches on the initiation and maintenance of weekly PA for patients post ETT. Participants who were referred to an ETT center but had a negative-test (ie, stress tests results indicated no apparent cardiac issues) were randomized to one of four treatment arms: (1) increased environmental accessibility to PA resources via the provision of a free voucher to a fitness facility in close proximity to their home or workplace (ENV), (2) a tailored social cognitive intervention (SC) using a "5 As"-based (ask, advise, assess, assist, and arrange) personal action planning tool, (3) combined intervention of both ENV and SC approaches (COMBO), or (4) a matched contact nutrition control (CON). Each intervention was delivered using a computer-based interactive session. A general linear model for repeated measures was conducted with change in PA behavior from baseline to 1-month post interactive computer session as the primary outcome. AB - RESULTS: Sedentary participants (n=452; 34.7% participation rate) without a gym membership (mean age 58.57 years; 59% female, 78% white, 12% black, 11% Hispanic) completed a baseline assessment and an interactive computer session. PA increased across the study sample (F1,441=30.03, P<.001). However, a time by condition interaction (F3,441=8.33, P<.001) followed by post hoc analyses indicated that SC participants exhibited a significant increase in weekly PA participation (mean 45.1, SD 10.2) compared to CON (mean -2.5, SD 10.8, P=.004) and ENV (mean 8.3, SD 8.1, P<.05). Additionally, COMBO participants exhibited a significant increase in weekly PA participation (mean 53.4, SD 8.9) compared to CON (P<.001) and ENV (P=.003) participants. There were no significant differences between ENV and CON or between SC and COMBO. AB - CONCLUSIONS: A brief, computer-based, interactive personal action planning session may be an effective tool to initiate PA within a health care setting, in particular as part of the ETT system. AB - TRIAL REGISTRATION: Clinicaltrials.gov NCT00432133, http://clinicaltrials.gov/ct2/show/NCT00432133 (Archived by WebCite at http://www.webcitation.org/6aa8X3mw1). ES - 1438-8871 IL - 1438-8871 DI - v17i8e206 DO - https://dx.doi.org/10.2196/jmir.3759 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, N.I.H., Extramural ID - 26303347 [pubmed] ID - v17i8e206 [pii] ID - 10.2196/jmir.3759 [doi] ID - PMC4642390 [pmc] PP - epublish PH - 2014/08/06 [received] PH - 2015/07/08 [accepted] PH - 2015/05/08 [revised] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT00432133 SA - ClinicalTrials.gov/NCT00432133 SL - https://clinicaltrials.gov/search/term=NCT00432133 SL - https://clinicaltrials.gov/search/term=NCT00432133 GI - No: R01 DK070553 Organization: (DK) *NIDDK NIH HHS* Country: United States No: R01DK070553 Organization: (DK) *NIDDK NIH HHS* Country: United States LG - English EP - 20150824 DP - 2015 Aug 24 DC - 20150825 EZ - 2015/08/26 06:00 DA - 2016/03/11 06:00 DT - 2015/08/26 06:00 YR - 2015 ED - 20160310 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26303347 <122. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26303347 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Almeida FA AU - Smith-Ray RL AU - Dzewaltowski DA AU - Glasgow RE AU - Lee RE AU - Thomas DS AU - Xu S AU - Estabrooks PA AI - Almeida, Fabio A; ORCID: http://orcid.org/0000-0002-2404-0694 AI - Smith-Ray, Renae L; ORCID: http://orcid.org/0000-0001-9642-7727 AI - Dzewaltowski, David A; ORCID: http://orcid.org/0000-0002-6592-1041 AI - Glasgow, Russell E; ORCID: http://orcid.org/0000-0003-4218-3231 AI - Lee, Rebecca E; ORCID: http://orcid.org/0000-0002-9011-0689 AI - Thomas, Deborah S K; ORCID: http://orcid.org/0000-0002-9594-9790 AI - Xu, Stanley; ORCID: http://orcid.org/0000-0002-4750-7672 AI - Estabrooks, Paul A; ORCID: http://orcid.org/0000-0003-2261-9886 FA - Almeida, Fabio A FA - Smith-Ray, Renae L FA - Dzewaltowski, David A FA - Glasgow, Russell E FA - Lee, Rebecca E FA - Thomas, Deborah S K FA - Xu, Stanley FA - Estabrooks, Paul A IN - Almeida, Fabio A. Implementation and Systems Science Laboratory, Department of Human, Nutrition, Foods, and Exercise, Virginia Tech, Roanoke, VA, United States. falmeida@vt.edu. TI - An Interactive Computer Session to Initiate Physical Activity in Sedentary Cardiac Patients: Randomized Controlled Trial. SO - Journal of Medical Internet Research. 17(8):e206, 2015 Aug 24 AS - J Med Internet Res. 17(8):e206, 2015 Aug 24 NJ - Journal of medical Internet research PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 100959882 IO - J. Med. Internet Res. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642390 SB - Index Medicus CP - Canada MH - Aged MH - *Cognitive Therapy MH - *Exercise MH - Exercise Test MH - Female MH - *Fitness Centers MH - *Heart Diseases/di [Diagnosis] MH - Humans MH - Internet MH - Linear Models MH - Male MH - Middle Aged MH - Motor Activity MH - *Risk Reduction Behavior MH - *Sedentary Lifestyle MH - Treatment Outcome MH - *User-Computer Interface KW - behavioral research; cardiovascular diseases; exercise, physical; human computer interaction; interactive media; treadmill test AB - BACKGROUND: Physical activity (PA) improves many facets of health. Despite this, the majority of American adults are insufficiently active. Adults who visit a physician complaining of chest pain and related cardiovascular symptoms are often referred for further testing. However, when this testing does not reveal an underlying disease or pathology, patients typically receive no additional standard care services. A PA intervention delivered within the clinic setting may be an effective strategy for improving the health of this population at a time when they may be motivated to take preventive action. AB - OBJECTIVE: Our aim was to determine the effectiveness of a tailored, computer-based, interactive personal action planning session to initiate PA among a group of sedentary cardiac patients following exercise treadmill testing (ETT). AB - METHODS: This study was part of a larger 2x2 randomized controlled trial to determine the impact of environmental and social-cognitive intervention approaches on the initiation and maintenance of weekly PA for patients post ETT. Participants who were referred to an ETT center but had a negative-test (ie, stress tests results indicated no apparent cardiac issues) were randomized to one of four treatment arms: (1) increased environmental accessibility to PA resources via the provision of a free voucher to a fitness facility in close proximity to their home or workplace (ENV), (2) a tailored social cognitive intervention (SC) using a "5 As"-based (ask, advise, assess, assist, and arrange) personal action planning tool, (3) combined intervention of both ENV and SC approaches (COMBO), or (4) a matched contact nutrition control (CON). Each intervention was delivered using a computer-based interactive session. A general linear model for repeated measures was conducted with change in PA behavior from baseline to 1-month post interactive computer session as the primary outcome. AB - RESULTS: Sedentary participants (n=452; 34.7% participation rate) without a gym membership (mean age 58.57 years; 59% female, 78% white, 12% black, 11% Hispanic) completed a baseline assessment and an interactive computer session. PA increased across the study sample (F1,441=30.03, P<.001). However, a time by condition interaction (F3,441=8.33, P<.001) followed by post hoc analyses indicated that SC participants exhibited a significant increase in weekly PA participation (mean 45.1, SD 10.2) compared to CON (mean -2.5, SD 10.8, P=.004) and ENV (mean 8.3, SD 8.1, P<.05). Additionally, COMBO participants exhibited a significant increase in weekly PA participation (mean 53.4, SD 8.9) compared to CON (P<.001) and ENV (P=.003) participants. There were no significant differences between ENV and CON or between SC and COMBO. AB - CONCLUSIONS: A brief, computer-based, interactive personal action planning session may be an effective tool to initiate PA within a health care setting, in particular as part of the ETT system. AB - TRIAL REGISTRATION: Clinicaltrials.gov NCT00432133, http://clinicaltrials.gov/ct2/show/NCT00432133 (Archived by WebCite at http://www.webcitation.org/6aa8X3mw1). ES - 1438-8871 IL - 1438-8871 DI - v17i8e206 DO - https://dx.doi.org/10.2196/jmir.3759 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, N.I.H., Extramural ID - 26303347 [pubmed] ID - v17i8e206 [pii] ID - 10.2196/jmir.3759 [doi] ID - PMC4642390 [pmc] PP - epublish PH - 2014/08/06 [received] PH - 2015/07/08 [accepted] PH - 2015/05/08 [revised] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT00432133 SL - https://clinicaltrials.gov/search/term=NCT00432133 GI - No: R01 DK070553 Organization: (DK) *NIDDK NIH HHS* Country: United States No: R01DK070553 Organization: (DK) *NIDDK NIH HHS* Country: United States LG - English EP - 20150824 DP - 2015 Aug 24 DC - 20150825 EZ - 2015/08/26 06:00 DA - 2016/03/11 06:00 DT - 2015/08/26 06:00 YR - 2015 ED - 20160310 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=26303347 <123. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25516293 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Dabas S AU - Dewan A AU - Ranjan R AU - Dewan AK AU - Puri A AU - Shah SH AU - Sinha R FA - Dabas, Surender FA - Dewan, Abhinav FA - Ranjan, Reetesh FA - Dewan, Ajay Kumar FA - Puri, Anoop FA - Shah, Swati H FA - Sinha, Rupal IN - Dabas, Surender. Department of Surgical Oncology, Rajiv Gandhi Cancer Institute & Research Centre, Delhi, India. TI - Transoral robotic surgery in management of oropharyngeal cancers: a preliminary experience at a tertiary cancer centre in India. SO - International Journal of Clinical Oncology. 20(4):693-700, 2015 Aug AS - Int J Clin Oncol. 20(4):693-700, 2015 Aug NJ - International journal of clinical oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 9616295 IO - Int. J. Clin. Oncol. SB - Index Medicus CP - Japan MH - Adult MH - Aged MH - Aged, 80 and over MH - Cancer Care Facilities MH - Feasibility Studies MH - Female MH - Humans MH - India MH - Male MH - Middle Aged MH - Natural Orifice Endoscopic Surgery MH - *Oropharyngeal Neoplasms/su [Surgery] MH - Prospective Studies MH - *Robotic Surgical Procedures/mt [Methods] MH - Tertiary Care Centers AB - BACKGROUND: The aim of this observational prospective study was to determine the technical feasibility, safety and adequacy of surgical margins for transoral robotic surgery (TORS) in oropharyngeal cancers. AB - METHODS: From March 2013 to May 2014, 60 patients with oropharyngeal lesions underwent TORS with or without neck dissection using the 'DaVinci' robot. Patients were observed and data recorded on surgical time, blood loss, complications and functional outcome of patients. AB - RESULTS: All 60 patients underwent TORS, with neck dissection performed in 45 of the patients. A positive margin was seen in two patients (3.3 %). Intent to treatment was radical in 42 patients and salvage in 18 patients. None of the patients required tracheostomy, and one patient (1.66 %) died postoperatively. Postoperative complications in the form of primary haemorrhage required active intervention in three patients. Average estimated blood loss was 26.5 +/- 31.1 ml. Postoperatively, all patients had adequate swallowing and speech function with nasal twang reported in three patients on long-term follow up. Patients started tolerating oral feeds within a week of procedure (mean 3.96 days), with the nasogastric tube removed on the ninth postoperative day (mean 9.19 days). No long-term gastrostomy tube dependency was reported. AB - CONCLUSION: TORS is a safe, feasible, minimally invasive procedure in patients with oropharyngeal cancers. It has the least morbidity and offers benefits in terms of avoidance of tracheostomy tube, prolonged Ryle's tube and gastrostomy dependency. ES - 1437-7772 IL - 1341-9625 DO - https://dx.doi.org/10.1007/s10147-014-0774-3 PT - Journal Article PT - Observational Study ID - 25516293 [pubmed] ID - 10.1007/s10147-014-0774-3 [doi] PP - ppublish PH - 2014/09/18 [received] PH - 2014/11/19 [accepted] LG - English EP - 20141217 DP - 2015 Aug DC - 20150807 EZ - 2014/12/18 06:00 DA - 2016/03/10 06:00 DT - 2014/12/18 06:00 YR - 2015 ED - 20160309 RD - 20150807 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25516293 <124. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26192256 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Aboumohamed AA AU - Krane LS AU - Hemal AK FA - Aboumohamed, Ahmed A FA - Krane, Louis Spencer FA - Hemal, Ashok K IN - Aboumohamed, Ahmed A. Urology Department, Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina. IN - Krane, Louis Spencer. Urology Department, Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina. IN - Hemal, Ashok K. Urology Department, Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina. Electronic address: ahemal@wakehealth.edu. TI - Oncologic Outcomes Following Robot-Assisted Laparoscopic Nephroureterectomy with Bladder Cuff Excision for Upper Tract Urothelial Carcinoma. SO - Journal of Urology. 194(6):1561-6, 2015 Dec AS - J Urol. 194(6):1561-6, 2015 Dec NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Aged, 80 and over MH - *Carcinoma, Transitional Cell/mo [Mortality] MH - Carcinoma, Transitional Cell/pa [Pathology] MH - *Carcinoma, Transitional Cell/su [Surgery] MH - Female MH - Follow-Up Studies MH - Humans MH - Kaplan-Meier Estimate MH - *Kidney Neoplasms/mo [Mortality] MH - Kidney Neoplasms/pa [Pathology] MH - *Kidney Neoplasms/su [Surgery] MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - Neoplasm Invasiveness MH - Neoplasm Staging MH - *Nephrectomy/mt [Methods] MH - Prognosis MH - Proportional Hazards Models MH - Retrospective Studies MH - Risk Factors MH - *Robotic Surgical Procedures/mt [Methods] MH - *Ureter/su [Surgery] MH - *Ureteral Neoplasms/mo [Mortality] MH - Ureteral Neoplasms/pa [Pathology] MH - *Ureteral Neoplasms/su [Surgery] MH - *Urinary Bladder/su [Surgery] KW - carcinoma; mortality; nephrectomy; robotics; urinary bladder AB - PURPOSE: Robot-assisted laparoscopic nephroureterectomy with bladder cuff excision is a minimally invasive alternative to open surgery for managing upper tract urothelial carcinoma. We report oncologic outcomes following robot-assisted laparoscopic nephroureterectomy with bladder cuff excision. AB - MATERIALS AND METHODS: The records of the initial 65 patients who underwent robot-assisted laparoscopic nephroureterectomy with bladder cuff excision for upper tract urothelial carcinoma between 2008 and 2014 were reviewed from our institutional review board approved, prospectively maintained database. All patients underwent surgery with the single docking technique. Baseline demographic features, pathological variables and perioperative data were analyzed. Kaplan-Meier methodology was used for survival analysis. Cox proportional hazards regression was applied to determine the prognostic effect of different variables on survival. AB - RESULTS: Mean patient age was 69.1 years. Final pathological evaluation revealed pT2 stage or lower in 65% of patients, pT3 in 28.3% and pT4 in 6.7%. High grade pathological findings were present in 85% of patients, including 13.3% with concomitant carcinoma in situ and 30% with lymphovascular invasion. Median followup was 25.1 months (range 6 to 68.9). At 2 and 5 years overall survival was 86.9% and 62.6%, cancer specific survival was 92.9% and 69.5%, and recurrence-free survival was 65.3% and 57.1%, respectively. A total of 23 patients experienced disease recurrence. Bladder recurrence developed in 15 patients, 12 had isolated bladder recurrence and 8 had metastatic disease. On univariate analysis age greater than 70 years, preoperative hydronephrosis, nodal disease and concomitant carcinoma in situ were significantly associated with decreased recurrence-free survival (p=0.002, 0.04, 0.006 and 0.001, respectively). However, none was statistically significant on multivariate analysis. On univariate analysis impaired preoperative renal function (creatinine greater than 2 mg/dl) and lymphovascular invasion were associated with reduced cancer specific survival (p=0.03 and 0.01, respectively). However, only lymphovascular invasion was associated with decreased cancer specific survival on multivariate analysis (p=0.048). AB - CONCLUSIONS: Our reported data on oncologic outcomes following robot-assisted laparoscopic nephroureterectomy with bladder cuff excision for upper tract urothelial carcinoma demonstrate satisfactory oncologic control at intermediate term followup. Long-term outcomes are required to assess true efficacy. AB - Copyright © 2015 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(15)04414-6 DO - https://dx.doi.org/10.1016/j.juro.2015.07.081 PT - Clinical Study PT - Journal Article ID - 26192256 [pubmed] ID - S0022-5347(15)04414-6 [pii] ID - 10.1016/j.juro.2015.07.081 [doi] PP - ppublish PH - 2015/07/05 [accepted] LG - English EP - 20150717 DP - 2015 Dec DC - 20151120 EZ - 2015/07/21 06:00 DA - 2016/03/02 06:00 DT - 2015/07/21 06:00 YR - 2015 ED - 20160229 RD - 20151120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26192256 <125. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25899767 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ozkan B AU - Tunc B AU - Coskuner ER AU - Saglican Y AU - Yalcin V FA - Ozkan, Burak FA - Tunc, Burcin FA - Coskuner, Enis Rauf FA - Saglican, Yesim FA - Yalcin, Veli IN - Ozkan, Burak. Department of Urology, Faculty of Medicine, Acibadem Bakirkoy and Maslak Hospitals, Acibadem University, Halit Ziya Usakligil Cad. No: 1, 34140, Bakirkoy, Istanbul, Turkey, burakozkandoc@hotmail.com. TI - Role of anterior prostatic fat pad dissection for extended lymphadenectomy in prostate cancer: a non-randomized study of 100 patients. SO - International Urology & Nephrology. 47(6):959-64, 2015 Jun AS - Int Urol Nephrol. 47(6):959-64, 2015 Jun NJ - International urology and nephrology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - guq, 0262521 IO - Int Urol Nephrol SB - Index Medicus CP - Netherlands MH - *Adipose Tissue/pa [Pathology] MH - Aged MH - Humans MH - *Lymph Node Excision/mt [Methods] MH - *Lymph Nodes/pa [Pathology] MH - Male MH - Middle Aged MH - *Prostate/pa [Pathology] MH - Prostatectomy MH - *Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Retrospective Studies AB - PURPOSE: To determine the incidence and significance of lymph nodes found in anterior prostatic fat pad (APFP) and to evaluate the risk factors for the lymph node presence at the APFP according to preoperative and postoperative characteristics during the robot-assisted radical prostatectomy (RARP). AB - METHODS: Between January 2011 and December 2014, 100 consecutive patients (47-77) with clinically localized prostate cancer underwent APFP excision during RARP at a single institute. Extended pelvic lymph node dissection was also performed to moderate- and high-risk patients (86 patients). Preoperative and postoperative findings were recorded, and descriptive analyses and multivariable analyses to predict the presence of lymph node within APFP were performed. AB - RESULTS: Lymph nodes within APFP were detected in nine (9 %) patients. None of the patients had metastatic lymph node in APFP. Preoperatively, mean PSA levels (14.22 vs. 8.6, p = 0.0001), biopsy Gleason score (p = 0.002) and radical prostatectomy pathology Gleason score (p = 0.001) were higher in patients with lymph nodes at the APFP tissue. Pelvic lymph node metastases were detected in seven of 86 (8 %) patients. Of these seven patients, four (57 %) had lymph nodes at the anterior prostatic fatty pad (p = 0.0001). AB - CONCLUSION: APFP dissection must be done regardless of the radical prostatectomy technique chosen. In our opinion, it is not necessary to do pathological examination of the APFP tissue routinely except for the patients with high preoperative PSA values, patients with high prostate biopsy Gleason scores and patients at high risk in order to save time and cost. ES - 1573-2584 IL - 0301-1623 DO - https://dx.doi.org/10.1007/s11255-015-0982-4 PT - Clinical Study PT - Journal Article ID - 25899767 [pubmed] ID - 10.1007/s11255-015-0982-4 [doi] PP - ppublish PH - 2015/02/18 [received] PH - 2015/04/10 [accepted] LG - English EP - 20150422 DP - 2015 Jun DC - 20150527 EZ - 2015/04/23 06:00 DA - 2016/02/26 06:00 DT - 2015/04/23 06:00 YR - 2015 ED - 20160225 RD - 20150527 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25899767 <126. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25392618 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Crusco S AU - Jackson T AU - Advincula A FA - Crusco, Salvatore FA - Jackson, Tiffany FA - Advincula, Arnold IN - Crusco, Salvatore. College of Medicine, University of Central Florida, Orlando, FL, USA. IN - Jackson, Tiffany. Florida Hospital Celebration Health, Celebration, FL, USA. IN - Advincula, Arnold. Florida Hospital Celebration Health, Celebration, FL, USA. TI - Comparing the da Vinci si single console and dual console in teaching novice surgeons suturing techniques. SO - Journal of the Society of Laparoendoscopic Surgeons. 18(3), 2014 Jul-Sep AS - J Soc Laparoendosc Surg. 18(3), 2014 Jul-Sep NJ - JSLS : Journal of the Society of Laparoendoscopic Surgeons PI - Journal available in: Print PI - Citation processed from: Internet JC - 100884618, c8o IO - JSLS PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154408 SB - Index Medicus CP - United States MH - Adult MH - *Education, Medical/mt [Methods] MH - Equipment Design MH - Female MH - Humans MH - Male MH - *Robotics/ed [Education] MH - Robotics/is [Instrumentation] MH - *Surgeons/ed [Education] MH - *Suture Techniques/ed [Education] MH - Young Adult KW - Robot-assisted laparoscopic surgery; Robotics; Simulation training; Teaching; da Vinci Si AB - BACKGROUND AND OBJECTIVES: Robot-assisted laparoscopic surgery is often taught with the surgical mentor at the surgeon console and the trainee at the patient's bedside. The da Vinci dual console (Intuitive Surgical, Sunnyvale, California) allows a surgical mentor to teach with both the mentor and the trainee working at a surgeon console simultaneously. The purpose of this study is to evaluate the effectiveness of the dual console versus the single console for teaching medical students robotic tasks. AB - METHODS: Forty novice medical students were randomized to either the da Vinci single-console or dual-console group and were taught 4 knot-tying techniques by a surgical mentor. The students were timed while performing the tasks. AB - RESULTS: No statistically significant differences in mean task times were observed between the single- and dual-console groups: interrupted stitch with a 2-handed knot (300 seconds for single vs 294 seconds for dual, P=.59), interrupted stitch with a 1-handed knot (198 seconds for single vs 212 seconds for dual, P=.88), figure-of-8 stitch with a 2-handed knot (261 seconds for single vs 219 seconds for dual, P=.20), and figure-of-8 stitch with a 1-handed knot (200 seconds for single vs 199 seconds for dual, P=.53). AB - CONCLUSION: No significant difference was observed in performance time when teaching knot-tying techniques to medical students using the da Vinci dual console compared with the single console. More research needs to be performed on the utility of the da Vinci dual console in surgical training. ES - 1938-3797 IL - 1086-8089 DI - e2014.00218 DI - JSLS-D-13-00218 DO - https://dx.doi.org/10.4293/JSLS.2014.00218 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 25392618 [pubmed] ID - 10.4293/JSLS.2014.00218 [doi] ID - JSLS-D-13-00218 [pii] ID - PMC4154408 [pmc] PP - ppublish LG - English DP - 2014 Jul-Sep DC - 20141113 EZ - 2014/11/14 06:00 DA - 2016/02/26 06:00 DT - 2014/11/14 06:00 YR - 2014 ED - 20160225 RD - 20161020 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25392618 <127. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25392618 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Crusco S AU - Jackson T AU - Advincula A FA - Crusco, Salvatore FA - Jackson, Tiffany FA - Advincula, Arnold IN - Crusco, Salvatore. College of Medicine, University of Central Florida, Orlando, FL, USA. IN - Jackson, Tiffany. Florida Hospital Celebration Health, Celebration, FL, USA. IN - Advincula, Arnold. Florida Hospital Celebration Health, Celebration, FL, USA. TI - Comparing the da Vinci si single console and dual console in teaching novice surgeons suturing techniques. SO - Journal of the Society of Laparoendoscopic Surgeons. 18(3), 2014 Jul-Sep AS - J Soc Laparoendosc Surg. 18(3), 2014 Jul-Sep NJ - JSLS : Journal of the Society of Laparoendoscopic Surgeons PI - Journal available in: Print PI - Citation processed from: Internet JC - 100884618, c8o IO - JSLS PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154408 SB - Index Medicus CP - United States MH - Adult MH - *Education, Medical/mt [Methods] MH - Equipment Design MH - Female MH - Humans MH - Male MH - *Robotics/ed [Education] MH - Robotics/is [Instrumentation] MH - *Surgeons/ed [Education] MH - *Suture Techniques/ed [Education] MH - Young Adult KW - Robot-assisted laparoscopic surgery; Robotics; Simulation training; Teaching; da Vinci Si AB - BACKGROUND AND OBJECTIVES: Robot-assisted laparoscopic surgery is often taught with the surgical mentor at the surgeon console and the trainee at the patient's bedside. The da Vinci dual console (Intuitive Surgical, Sunnyvale, California) allows a surgical mentor to teach with both the mentor and the trainee working at a surgeon console simultaneously. The purpose of this study is to evaluate the effectiveness of the dual console versus the single console for teaching medical students robotic tasks. AB - METHODS: Forty novice medical students were randomized to either the da Vinci single-console or dual-console group and were taught 4 knot-tying techniques by a surgical mentor. The students were timed while performing the tasks. AB - RESULTS: No statistically significant differences in mean task times were observed between the single- and dual-console groups: interrupted stitch with a 2-handed knot (300 seconds for single vs 294 seconds for dual, P=.59), interrupted stitch with a 1-handed knot (198 seconds for single vs 212 seconds for dual, P=.88), figure-of-8 stitch with a 2-handed knot (261 seconds for single vs 219 seconds for dual, P=.20), and figure-of-8 stitch with a 1-handed knot (200 seconds for single vs 199 seconds for dual, P=.53). AB - CONCLUSION: No significant difference was observed in performance time when teaching knot-tying techniques to medical students using the da Vinci dual console compared with the single console. More research needs to be performed on the utility of the da Vinci dual console in surgical training. ES - 1938-3797 IL - 1086-8089 DI - e2014.00218 DI - JSLS-D-13-00218 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 25392618 [pubmed] ID - JSLS-D-13-00218 [pii] ID - PMC4154408 [pmc] PP - ppublish LG - English DP - 2014 Jul-Sep DC - 20141113 EZ - 2014/11/14 06:00 DA - 2016/02/26 06:00 DT - 2014/11/14 06:00 YR - 2014 ED - 20160225 RD - 20161222 UP - 20161223 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=25392618 <128. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25059998 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Saglam R AU - Muslumanoglu AY AU - Tokatli Z AU - Caskurlu T AU - Sarica K AU - Tasci AI AU - Erkurt B AU - Suer E AU - Kabakci AS AU - Preminger G AU - Traxer O AU - Rassweiler JJ FA - Saglam, Remzi FA - Muslumanoglu, Ahmet Yaser FA - Tokatli, Zafer FA - Caskurlu, Turhan FA - Sarica, Kemal FA - Tasci, Ali Ihsan FA - Erkurt, Bulent FA - Suer, Evren FA - Kabakci, Ahmet Sinan FA - Preminger, Glenn FA - Traxer, Olivier FA - Rassweiler, Jens J IN - Saglam, Remzi. Department of Urology, Medicana International Hospital, Ankara, Turkey. IN - Muslumanoglu, Ahmet Yaser. Department of Urology, Bagcilar Training Hospital, Istanbul, Turkey. IN - Tokatli, Zafer. Department of Urology, Medicana International Hospital, Ankara, Turkey. IN - Caskurlu, Turhan. Department of Urology, Medeniyet University Hospital, Istanbul, Turkey. IN - Sarica, Kemal. Department of Urology, Kartal Training Hospital, Istanbul, Turkey. IN - Tasci, Ali Ihsan. Department of Urology, Bakirkoy Training Hospital, Istanbul, Turkey. IN - Erkurt, Bulent. Department of Urology, Medipol University Medical School Hospital, Istanbul, Turkey. IN - Suer, Evren. Department of Urology, Ankara University Medical School Hospital, Ankara, Turkey. IN - Kabakci, Ahmet Sinan. Department of Bioengineering, Hacettepe University, Ankara, Turkey. IN - Preminger, Glenn. Division of Urologic Surgery, Duke University Medical Center, Durham, NC, USA. IN - Traxer, Olivier. Department of Urology, Universite Pierre et Marie Curie, Hopital Tenon, Paris, France. IN - Rassweiler, Jens J. Department of Urology, SLK Kliniken Heilbronn, Heilbronn, Germany; Department of Urology, University of Heidelberg, Heidelberg, Germany. Electronic address: jens.rassweiler@slk-kliniken.de. TI - A new robot for flexible ureteroscopy: development and early clinical results (IDEAL stage 1-2b). CM - Comment in: J Urol. 2015 Apr;193(4):1277; PMID: 25890521 SO - European Urology. 66(6):1092-100, 2014 Dec AS - Eur Urol. 66(6):1092-100, 2014 Dec NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Adolescent MH - Adult MH - Aged MH - Attitude of Health Personnel MH - Child MH - Equipment Design MH - Female MH - *Human Engineering MH - Humans MH - *Kidney Calculi/th [Therapy] MH - Male MH - Middle Aged MH - Operative Time MH - *Robotic Surgical Procedures/is [Instrumentation] MH - Surveys and Questionnaires MH - Treatment Outcome MH - *Ureteroscopy/is [Instrumentation] MH - Young Adult KW - Ergonomics; Retrograde intrarenal surgery; Robotics; Surgical manipulator; Telesurgery; Ureterorenoscopy; Urolithiasis AB - BACKGROUND: An improved armamentarium has had a significant impact on the emerging role of flexible ureteroscopy (FURS) for the management of nephrolithiasis; however, FURS still represents a challenging technique. AB - OBJECTIVE: To examine a robotic device designed for FURS for its impact on ergonomics and outcome of the procedure based on the IDEAL (idea, development, evaluation, assessment, long-term study) framework. AB - DESIGN, SETTING, AND PARTICIPANTS: Roboflex Avicenna consists of a surgeon's console and a manipulator for the flexible ureterorenoscope. Following experimental evaluation of the prototype (IDEAL stage 1) and receipt of ethical approval, seven surgeons treated 81 patients (mean age: 42 yr [range: 6-68]) with renal calculi (mean volume: 1296+/-544 mm(3) [range: 432-3100 mm3]) in an observational study (IDEAL stage 2). AB - SURGICAL PROCEDURE: Robotic FURS was performed with the Roboflex Avicenna robotic device. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Numerical data were analysed with the Mann-Whitney test, and categorical variables were analysed using the chi-square test or Fisher exact test. P values <0.05 were considered statistically significant. AB - RESULTS AND LIMITATIONS: Mean robot docking time was 59.6+/-45 s. Mean operative time was 74min (range: 40-182). Mean fragmentation speed was 29.1+/-6.1 mm3/min. Ergonomics based on a validated questionnaire showed significant advantage for robotic FURS (total score: 5.6 vs 31.3; p<0.01). A 10/12F-access sheath was used in 72 patients. Two cases required secondary FURS, one because of malfunction of the flexible digital ureteroscope and another because of larger residual fragments. In the remaining 79 cases, complete stone disintegration was accomplished. AB - CONCLUSIONS: Roboflex Avicenna provides a suitable and safe platform for robotic FURS with significant improvement of ergonomics. Future studies should evaluate its impact on the clinical outcome of FURS. AB - PATIENT SUMMARY: Robotic flexible ureteroscopy (FURS) was performed with the Roboflex Avicenna robotic device. Results showed that Roboflex Avicenna provides a suitable and safe platform for robotic FURS with significant improvement of ergonomics. AB - Copyright © 2014 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(14)00621-6 DO - https://dx.doi.org/10.1016/j.eururo.2014.06.047 PT - Journal Article PT - Observational Study ID - 25059998 [pubmed] ID - S0302-2838(14)00621-6 [pii] ID - 10.1016/j.eururo.2014.06.047 [doi] PP - ppublish PH - 2014/04/07 [received] PH - 2014/06/27 [accepted] LG - English EP - 20140721 DP - 2014 Dec DC - 20141202 EZ - 2014/07/26 06:00 DA - 2016/02/26 06:00 DT - 2014/07/26 06:00 YR - 2014 ED - 20160223 RD - 20141202 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25059998 <129. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25041850 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kaouk JH AU - Haber GP AU - Autorino R AU - Crouzet S AU - Ouzzane A AU - Flamand V AU - Villers A FA - Kaouk, Jihad H FA - Haber, Georges-Pascal FA - Autorino, Riccardo FA - Crouzet, Sebastien FA - Ouzzane, Adil FA - Flamand, Vincent FA - Villers, Arnauld IN - Kaouk, Jihad H. Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address: kaoukj@ccf.org. IN - Haber, Georges-Pascal. Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA. IN - Autorino, Riccardo. Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA. IN - Crouzet, Sebastien. Department of Urology and Transplantation, Edouard Herriot Hospital, Lyon, France. IN - Ouzzane, Adil. Department of Urology, CHU Lille, University Lille Nord de France, Lille, France. IN - Flamand, Vincent. Department of Urology, CHU Lille, University Lille Nord de France, Lille, France. IN - Villers, Arnauld. Department of Urology, CHU Lille, University Lille Nord de France, Lille, France. TI - A novel robotic system for single-port urologic surgery: first clinical investigation. CM - Comment in: Eur Urol. 2014 Dec;66(6):1044-5; PMID: 25123322 SO - European Urology. 66(6):1033-43, 2014 Dec AS - Eur Urol. 66(6):1033-43, 2014 Dec NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Aged MH - Feasibility Studies MH - Female MH - Humans MH - *Kidney Neoplasms/su [Surgery] MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy/is [Instrumentation] MH - Male MH - Middle Aged MH - *Neoplasm Recurrence, Local/rt [Radiotherapy] MH - Nephrectomy/ae [Adverse Effects] MH - *Nephrectomy/is [Instrumentation] MH - Nephrectomy/mt [Methods] MH - Prospective Studies MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/is [Instrumentation] MH - *Prostatic Neoplasms/su [Surgery] MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures/is [Instrumentation] MH - Technology Assessment, Biomedical MH - Warm Ischemia KW - Nephrectomy; Radical prostatectomy; Robotic surgery; Single-port surgery; Single-site surgery; Urology AB - BACKGROUND: The idea of performing a laparoscopic procedure through a single abdominal incision was conceived with the aim of expediting postoperative recovery. AB - OBJECTIVE: To determine the clinical feasibility and safety of single-port urologic procedures by using a novel robotic surgical system. AB - DESIGN, SETTING, AND PARTICIPANTS: This was a prospective institutional review board-approved, Innovation, Development, Exploration, Assessment, Long-term Study (IDEAL) phase 1 study. After enrollment, patients underwent a major urologic robotic single-port procedure over a 3-wk period in July 2010. The patients were followed for 3 yr postoperatively. AB - INTERVENTION: Different types of urologic surgeries were performed using the da Vinci SP Surgical System. This system is intended to provide the same core clinical capabilities as the existing multiport da Vinci system, except that three articulating endoscopic instruments and an articulating endoscopic camera are inserted into the patient through a single robotic port. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: The main outcomes were the technical feasibility of the procedures (as measured by the rate of conversions) and the safety of the procedures (as measured by the incidence of perioperative complications). Secondary end points consisted of evaluating other key surgical perioperative outcomes as well as midterm functional and oncologic outcomes. AB - RESULTS AND LIMITATIONS: A total of 19 patients were enrolled in the study. Eleven of them underwent radical prostatectomy; eight subjects underwent nephrectomy procedures (partial nephrectomy, four; radical nephrectomy, two; and simple nephrectomy, two). There were no conversions to alternative surgical approaches. Overall, two major (Clavien grade 3b) postoperative complications were observed in the radical prostatectomy group and none in the nephrectomy group. At 1-yr follow-up, one radical prostatectomy patient experienced biochemical recurrence, which was successfully treated with salvage radiation therapy. The median warm ischemia time for three of the partial nephrectomies was 38 min. At 3-yr follow-up all patients presented a preserved renal function; none had tumor recurrence. Study limitations include the small sample and the lack of a control group. AB - CONCLUSIONS: We describe the first clinical application of a novel robotic platform specifically designed for single-port urologic surgery. Major urologic procedures were successfully completed without conversions. Further assessment is warranted to corroborate these promising findings. AB - PATIENT SUMMARY: A novel purpose-built robotic system enables surgeons to perform safely and effectively a variety of major urologic procedures through a single small abdominal incision. AB - TRIAL REGISTRATION: The study was registered on www.ClinicalTrials.gov (NCT02136121). AB - Copyright © 2014 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(14)00613-7 DO - https://dx.doi.org/10.1016/j.eururo.2014.06.039 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 25041850 [pubmed] ID - S0302-2838(14)00613-7 [pii] ID - 10.1016/j.eururo.2014.06.039 [doi] PP - ppublish PH - 2014/05/13 [received] PH - 2014/06/23 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT02136121 SL - https://clinicaltrials.gov/search/term=NCT02136121 LG - English EP - 20140717 DP - 2014 Dec DC - 20141202 EZ - 2014/07/22 06:00 DA - 2016/02/26 06:00 DT - 2014/07/22 06:00 YR - 2014 ED - 20160223 RD - 20141202 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25041850 <130. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25421934 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tan-Kim J AU - Nager CW AU - Grimes CL AU - Luber KM AU - Lukacz ES AU - Brown HW AU - Ferrante KL AU - Dyer KY AU - Kirby AC AU - Menefee SA FA - Tan-Kim, Jasmine FA - Nager, Charles W FA - Grimes, Cara L FA - Luber, Karl M FA - Lukacz, Emily S FA - Brown, Heidi W FA - Ferrante, Kimberly L FA - Dyer, Keisha Y FA - Kirby, Anna C FA - Menefee, Shawn A IN - Tan-Kim, Jasmine. Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Ob/Gyn, Kaiser Permanente San Diego, 3250 Fordham St, San Diego, CA, 92110, USA, jasmine.tankim@gmail.com. TI - A randomized trial of vaginal mesh attachment techniques for minimally invasive sacrocolpopexy. SO - International Urogynecology Journal. 26(5):649-56, 2015 May AS - Int Urogynecol J Pelvic Floor Dysfunct. 26(5):649-56, 2015 May NJ - International urogynecology journal PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - cl5, 9514583, 101567041 IO - Int Urogynecol J SB - Index Medicus CP - England MH - Aged MH - Attitude of Health Personnel MH - Female MH - Humans MH - Laparoscopy MH - Middle Aged MH - Operative Time MH - Pelvic Organ Prolapse/su [Surgery] MH - Robotic Surgical Procedures MH - Sacrum/su [Surgery] MH - Single-Blind Method MH - *Surgical Mesh MH - *Suture Techniques MH - *Sutures MH - Treatment Outcome MH - Vagina/su [Surgery] AB - INTRODUCTION AND HYPOTHESIS: We investigated the efficiency and efficacy of vaginal mesh attachment using interrupted, non-barbed, delayed absorbable sutures in comparison with a running, barbed, delayed absorbable suture during laparoscopic sacrocolpopexy (LSC) and robotic sacrocolpopexy (RSC). AB - METHODS: Women undergoing LSC or RSC were recruited. Participants were randomized to at least six 0 PDS non-barbed interrupted sutures or at least six passes of a 1 PDS barbed suture (QuillTM) on each anterior and posterior polypropylene mesh leaflet. The primary outcome was the time to attach the mesh to the vagina. The LSC and RSC groups were block randomized by suture type. Secondary outcomes included: (1) intraoperative surgeon assessment of satisfaction as measured using a 10-cm visual analog scale (VAS), (2) postoperative POP-Q evaluation for anatomic failure, and (3) overall appearance of vaginal walls measured using a VAS. AB - RESULTS: Of the 64 included subjects who were randomized, 32 had mesh attachment with the barbed suture (16 LSC, 16 RSC) and 32 had attachment with non-barbed sutures (16 LSC, 16 RSC). Among all the subjects (LSC and RSC), the non-barbed suture group had significantly longer mesh attachment times than the barbed suture group (42 vs. 29 min, p < 0.001). The non-barbed suture group had significantly better scores for intraoperative ease of suture placement, surgeon satisfaction with mesh appearance, and global satisfaction. At 12 months, there were no significant differences in anatomic failure between the suture groups or overall appearance of the vaginal walls (p > 0.05). AB - CONCLUSIONS: The barbed suture technique was 11 - 16 min faster for attaching mesh to the vagina than the non-barbed suture technique. Anatomic outcomes at 12 months were comparable between the suture groups. It is reasonable to use a running, barbed suture in minimally invasive sacrocolpopexy. ES - 1433-3023 IL - 0937-3462 DO - https://dx.doi.org/10.1007/s00192-014-2566-8 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 25421934 [pubmed] ID - 10.1007/s00192-014-2566-8 [doi] PP - ppublish PH - 2014/09/10 [received] PH - 2014/11/04 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01551992 SA - ClinicalTrials.gov/NCT01608568 SL - https://clinicaltrials.gov/search/term=NCT01551992 SL - https://clinicaltrials.gov/search/term=NCT01608568 LG - English EP - 20141125 DP - 2015 May DC - 20150423 EZ - 2014/11/26 06:00 DA - 2016/02/20 06:00 DT - 2014/11/26 06:00 YR - 2015 ED - 20160219 RD - 20150423 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25421934 <131. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25138578 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Yoon YE AU - Choi KH AU - Lee KS AU - Kim KH AU - Rha KH AU - Choi YD AU - Han WK FA - Yoon, Young Eun FA - Choi, Kyung Hwa FA - Lee, Kwang Suk FA - Kim, Kwang Hyun FA - Rha, Koon Ho FA - Choi, Young Deuk FA - Han, Woong Kyu IN - Yoon, Young Eun. Department of Urology, Urological Science Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, South Korea. TI - Usefulness of the diameter-axial-polar nephrometry score for predicting perioperative parameters in robotic partial nephrectomy. SO - World Journal of Urology. 33(6):841-5, 2015 Jun AS - World J Urol. 33(6):841-5, 2015 Jun NJ - World journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - bry, 8307716 IO - World J Urol SB - Index Medicus CP - Germany MH - Adult MH - Anthropometry MH - Blood Loss, Surgical/sn [Statistics & Numerical Data] MH - Carcinoma, Renal Cell/dg [Diagnostic Imaging] MH - *Carcinoma, Renal Cell/pa [Pathology] MH - Carcinoma, Renal Cell/su [Surgery] MH - Cohort Studies MH - Female MH - Glomerular Filtration Rate MH - Humans MH - Kidney/dg [Diagnostic Imaging] MH - *Kidney/pa [Pathology] MH - Kidney Neoplasms/dg [Diagnostic Imaging] MH - *Kidney Neoplasms/pa [Pathology] MH - Kidney Neoplasms/su [Surgery] MH - Laparoscopy MH - Linear Models MH - Magnetic Resonance Imaging MH - Male MH - Middle Aged MH - *Nephrectomy MH - Organ Size MH - *Postoperative Complications/ep [Epidemiology] MH - *Renal Insufficiency, Chronic/ep [Epidemiology] MH - Retrospective Studies MH - Robotic Surgical Procedures MH - Severity of Illness Index MH - Tomography, X-Ray Computed MH - Treatment Outcome MH - Tumor Burden MH - Warm Ischemia/sn [Statistics & Numerical Data] AB - PURPOSE: The present study aimed to verify the association between diameter-axial-polar (DAP) nephrometry and surgical outcomes, postoperative renal function, and perioperative complications in patients undergoing robotic partial nephrectomy (RPN). AB - METHODS: Diameter-axial-polar nephrometry was assessed using computed tomography or magnetic resonance imaging on 158 patients who received RPN between July 2007 and February 2013. Demographic data, surgical data, and perioperative complications were recorded, and percent change between the preoperative and last estimated glomerular filtration rate (eGFR) was determined. Linear regression analysis was conducted to assess the relationship between the DAP sum score and warm ischemia time (WIT), estimated blood loss (EBL), and percent decrease in eGFR. Multivariable linear regression analysis was conducted to determine the relationship between each DAP scoring parameter and surgical outcomes. AB - RESULTS: The median patient age was 50.5 years and median DAP sum score was 6. On linear regression, the DAP sum score was associated with WIT and EBL. On multivariable regression, all DAP parameters were associated with WIT, but the polar distance was not associated with EBL. Patients with a higher DAP sum score showed greater decrease in eGFR after RPN. Patients with a DAP sum score of 6 or higher had a higher risk of major complications than those with a DAP sum score below 6. AB - CONCLUSIONS: Diameter-axial-polar nephrometry predicted WIT and EBL in patients who underwent RPN. It was also associated with the decrease in eGFR and rate of major perioperative complications, and thus can be useful for surgical planning or patient counseling before RPN. ES - 1433-8726 IL - 0724-4983 DO - https://dx.doi.org/10.1007/s00345-014-1372-8 PT - Clinical Study PT - Journal Article ID - 25138578 [pubmed] ID - 10.1007/s00345-014-1372-8 [doi] PP - ppublish PH - 2014/04/04 [received] PH - 2014/07/29 [accepted] LG - English EP - 20140820 DP - 2015 Jun DC - 20150529 EZ - 2014/08/21 06:00 DA - 2016/02/18 06:00 DT - 2014/08/21 06:00 YR - 2015 ED - 20160217 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25138578 <132. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24973046 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Morgan MS AU - Shakir NA AU - Garcia-Gil M AU - Ozayar A AU - Gahan JC AU - Friedlander JI AU - Roehrborn CG AU - Cadeddu JA FA - Morgan, Monica S C FA - Shakir, Nabeel A FA - Garcia-Gil, Maurilio FA - Ozayar, Asim FA - Gahan, Jeffrey C FA - Friedlander, Justin I FA - Roehrborn, Claus G FA - Cadeddu, Jeffrey A IN - Morgan, Monica S C. Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA, monica.morgan2@utsouthwestern.edu. TI - Single- versus dual-console robot-assisted radical prostatectomy: impact on intraoperative and postoperative outcomes in a teaching institution. SO - World Journal of Urology. 33(6):781-6, 2015 Jun AS - World J Urol. 33(6):781-6, 2015 Jun NJ - World journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - bry, 8307716 IO - World J Urol SB - Index Medicus CP - Germany MH - Adult MH - Aged MH - Anastomotic Leak/ep [Epidemiology] MH - Blood Loss, Surgical MH - Cohort Studies MH - Education, Medical, Graduate/mt [Methods] MH - *Erectile Dysfunction/ep [Epidemiology] MH - Hospitals, Teaching MH - Humans MH - *Intraoperative Complications/ep [Epidemiology] MH - Laparoscopy MH - Linear Models MH - Logistic Models MH - Lymph Node Excision/mt [Methods] MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Operative Time MH - Pelvis MH - *Postoperative Complications/ep [Epidemiology] MH - Prostatectomy/ed [Education] MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - Retrospective Studies MH - Robotic Surgical Procedures/ed [Education] MH - Robotic Surgical Procedures/is [Instrumentation] MH - *Robotic Surgical Procedures/mt [Methods] MH - Treatment Outcome MH - *Urinary Incontinence/ep [Epidemiology] MH - Urology/ed [Education] AB - OBJECTIVE: To compare the outcomes of robotic-assisted laparoscopic prostatectomy (RALP) using a dual versus single-console system in a resident training program using intraoperative, perioperative and postoperative measures. AB - METHODS: Patients with PCa who underwent RALP prior to and after implementing a dual-console system at an academic institution were reviewed from 2006-2012. All surgeries were performed by a single-faculty surgeon well after the learning curve was established. In all cases, chief residents participated in the surgery and performed progressively more portions. Demographic, intraoperative and pathologic parameters were obtained. Continence and erectile function were assessed at 6 and 12 months. Postoperative complications were graded using the Clavien-Dindo classification. Predictors of outcomes on univariate analysis were included in multivariate logistic or linear models. AB - RESULTS: Of 381 patients, 185 and 196 underwent single- or dual-console RALP, respectively. There was a significant decrease in mean operative time using the dual-console system (222 vs. 171 min, p < 0.0001) as well as in the incidence of intraoperative complications (8.65 vs. 1.53%, p < 0.0001) and postoperative complications (14.1 vs. 6.63%, p = 0.03.) Complications of Clavien grade >3a occurred more frequently with a single-console system (7 vs. 1%, p = 0.003.) Differences persisted when controlling for potential confounders by multivariate regression. Postoperative measures of continence, erectile function and the rate of biochemical recurrence were similar between cohorts. AB - CONCLUSIONS: When training resident surgeons to perform RALP, a dual-console system may improve intraoperative and perioperative outcomes. The dual-console may represent a safer, more efficient modality for robotic surgical education as compared to a single-console system. ES - 1433-8726 IL - 0724-4983 DO - https://dx.doi.org/10.1007/s00345-014-1349-7 PT - Clinical Study PT - Comparative Study PT - Journal Article ID - 24973046 [pubmed] ID - 10.1007/s00345-014-1349-7 [doi] PP - ppublish PH - 2014/05/02 [received] PH - 2014/06/16 [accepted] LG - English EP - 20140628 DP - 2015 Jun DC - 20150529 EZ - 2014/06/29 06:00 DA - 2016/02/18 06:00 DT - 2014/06/29 06:00 YR - 2015 ED - 20160217 RD - 20150529 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24973046 <133. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24928375 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Palisaar JR AU - Roghmann F AU - Brock M AU - Loppenberg B AU - Noldus J AU - von Bodman C FA - Palisaar, Juri R FA - Roghmann, Florian FA - Brock, Marko FA - Loppenberg, Bjorn FA - Noldus, Joachim FA - von Bodman, Christian IN - Palisaar, Juri R. Department of Urology, Marienhospital Herne, Ruhr-University Bochum, Widumer Strasse 8, 44627, Herne, Germany, Rein-jueri.palisaar@marienhospital-herne.de. TI - Predictors of short-term recovery of urinary continence after radical prostatectomy. SO - World Journal of Urology. 33(6):771-9, 2015 Jun AS - World J Urol. 33(6):771-9, 2015 Jun NJ - World journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - bry, 8307716 IO - World J Urol SB - Index Medicus CP - Germany MH - Aged MH - Biofeedback, Psychology MH - Cohort Studies MH - Electric Stimulation Therapy MH - Humans MH - Laparoscopy MH - Learning Curve MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Neoplasm Staging MH - Odds Ratio MH - Organ Sparing Treatments MH - Pelvic Floor MH - *Physical Therapy Modalities MH - Prostatectomy/mt [Methods] MH - *Prostatectomy/rh [Rehabilitation] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - *Recovery of Function MH - Retrospective Studies MH - Risk Factors MH - Robotic Surgical Procedures/mt [Methods] MH - Time Factors MH - Treatment Outcome MH - Urinary Catheterization/sn [Statistics & Numerical Data] MH - *Urinary Incontinence, Stress/rh [Rehabilitation] AB - PURPOSE: To evaluate treatment variables for early urinary continence status 6 weeks following radical prostatectomy. AB - METHODS: In this retrospective analysis, 4,028 consecutive patients underwent open radical retropubic (RRP) or robot-assisted transperitoneal prostatectomy (RARP) at a single academic institution (07/2003-07/2013). After discharge, patients were offered 3-week treatment in a rehabilitation facility. Patients who opted for rehabilitation (n = 2,998, 74.4%) represent our study cohort. Exclusion criteria were acute urinary retention after catheter removal (n = 55, 1.4%), incomplete datasets (n = 50, 1.2%) or refusal of rehabilitation (n = 925, 23.0%). Results of urinary continence were evaluated from final rehabilitation reports. Twenty-two clinical and oncological variables were statistically analysed in uni- and multivariable analyses to determine whether they were associated with early urinary continence status six weeks after radical prostatectomy. Odds ratios and 95% CI as well as p values were calculated. A p level of 0.05 was considered as significant. AB - RESULTS: Six weeks after surgery, 1,962 (65.4%) patients were continent (<1 pad/day) and 1,036 (34.6%) patients were considered incontinent. Age, clinical stage, PSA, ASA score, prior TURP, seminal vesicle invasion, Gleason score, nerve-sparing status, intraoperative blood loss, catheterisation time, OR time, surgical caseload >1,000 and the surgeon were associated with continence status on univariable analysis (p < 0.05). On multivariable analysis, nerve-sparing procedure (NS), clinical stage, individual surgeon, patient age, surgical procedure (RARP vs. RRP) and duration of catheterisation were independent predictors (p < 0.05) of incontinence status. AB - CONCLUSIONS: Strategies that can ensure NS procedures and early catheter removal should be applied to enable early recovery of urinary continence. ES - 1433-8726 IL - 0724-4983 DO - https://dx.doi.org/10.1007/s00345-014-1340-3 PT - Clinical Study PT - Journal Article ID - 24928375 [pubmed] ID - 10.1007/s00345-014-1340-3 [doi] PP - ppublish PH - 2014/04/16 [received] PH - 2014/06/03 [accepted] LG - English EP - 20140614 DP - 2015 Jun DC - 20150529 EZ - 2014/06/15 06:00 DA - 2016/02/18 06:00 DT - 2014/06/15 06:00 YR - 2015 ED - 20160217 RD - 20150529 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24928375 <134. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24908066 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Shin TY AU - Lim SK AU - Komninos C AU - Kim DW AU - Han WK AU - Hong SJ AU - Jung BH AU - Rha KH FA - Shin, Tae Young FA - Lim, Sey Kiat FA - Komninos, Christos FA - Kim, Dong Wook FA - Han, Woong Kyu FA - Hong, Sung Jun FA - Jung, Byung Ha FA - Rha, Koon Ho IN - Shin, Tae Young. Department of Urology, Chuncheon Sacred Hospital, Hallym Medical College, Chuncheon, South Korea. TI - Clinical values of selective-clamp technique in robotic partial nephrectomy. SO - World Journal of Urology. 33(6):763-9, 2015 Jun AS - World J Urol. 33(6):763-9, 2015 Jun NJ - World journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - bry, 8307716 IO - World J Urol SB - Index Medicus CP - Germany MH - Adult MH - Aged MH - *Carcinoma, Renal Cell/su [Surgery] MH - Case-Control Studies MH - Constriction MH - Databases, Factual MH - Female MH - Glomerular Filtration Rate MH - Humans MH - *Kidney Neoplasms/su [Surgery] MH - Male MH - Middle Aged MH - *Nephrectomy/mt [Methods] MH - *Postoperative Complications/ep [Epidemiology] MH - *Renal Insufficiency, Chronic/ep [Epidemiology] MH - Retrospective Studies MH - *Robotic Surgical Procedures/mt [Methods] MH - Treatment Outcome MH - *Warm Ischemia/mt [Methods] AB - PURPOSE: In the era of robotic partial nephrectomy (RPN), several efforts on improved renal functional outcome have been reported. Selective-clamp is a novel technique that eliminates global ischemia, the clinical value of which needs to be demonstrated. The purpose of this study was to compare the postoperative functional outcomes of patients who underwent selective-clamp and total-clamping RPN. AB - PATIENTS AND METHODS: From February 2009 to October 2012, a database of 126 consecutive patients who underwent RPN was retrospectively analyzed, 117 patients met our inclusion criteria and were stratified into two groups, 20 patients underwent selective-clamp RPN, and 97 patients underwent total-clamping RPN. Post hoc power analysis was subsequently performed for calculation of sufficient sample size. Demographics/tumor characteristics, functional outcomes and complications were analyzed. AB - RESULTS: All selective-clamp RPN cases were successfully performed. Mean tumor size was 3.4 cm [standard deviation (SD): +/-1.4], mean RENAL nephrometry score was 7.3 (SD: +/-2.0), and no Clavien-Dindo III-V complications were recorded. Selective-clamp RPN group had a significantly lower percentage decrease in the postoperative estimated glomerular filtration rate at 1 week (1.8 vs. 20.8 ml/min/1.73 m(2), p = 0.001) and 3 months (0 vs. 9.9 ml/min/1.73 m(2), p = 0.032) when compared with the total-clamping RPN group. There were no significant differences in surgical margin and complication rates. AB - CONCLUSIONS: Selective-clamp confers improved renal functional outcomes in comparison to total-clamping RPN, with acceptable complications and oncological outcomes even in large and complex tumors. ES - 1433-8726 IL - 0724-4983 DO - https://dx.doi.org/10.1007/s00345-014-1333-2 PT - Clinical Study PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 24908066 [pubmed] ID - 10.1007/s00345-014-1333-2 [doi] PP - ppublish PH - 2014/03/08 [received] PH - 2014/05/22 [accepted] LG - English EP - 20140608 DP - 2015 Jun DC - 20150529 EZ - 2014/06/09 06:00 DA - 2016/02/18 06:00 DT - 2014/06/09 06:00 YR - 2015 ED - 20160217 RD - 20150529 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24908066 <135. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25902817 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Speer T AU - Groesdonk HV AU - Zapf B AU - Buescher V AU - Beyse M AU - Duerr L AU - Gewert S AU - Krauss P AU - Poppleton A AU - Wagenpfeil S AU - Fliser D AU - Schaefers HJ AU - Klingele M FA - Speer, Timo FA - Groesdonk, Heinrich V FA - Zapf, Beate FA - Buescher, Vanessa FA - Beyse, Miriam FA - Duerr, Laura FA - Gewert, Stella FA - Krauss, Patrizia FA - Poppleton, Aaron FA - Wagenpfeil, Stefan FA - Fliser, Danilo FA - Schaefers, Hans-Joachim FA - Klingele, Matthias IN - Speer, Timo. Department of Internal Medicine, Nephrology and Hypertension, Saarland University Medical Centre, Kirrberger Strasse, D-66424, Homburg/Saar, Germany. timo.speer@uks.eu. IN - Groesdonk, Heinrich V. Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Centre, Homburg/Saar, Germany. heinrich.groesdonk@uks.eu. IN - Groesdonk, Heinrich V. Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Centre, Homburg/Saar, Germany. heinrich.groesdonk@uks.eu. IN - Zapf, Beate. Department of Internal Medicine, Nephrology and Hypertension, Saarland University Medical Centre, Kirrberger Strasse, D-66424, Homburg/Saar, Germany. beate.zapf@web.de. IN - Buescher, Vanessa. Department of Internal Medicine, Nephrology and Hypertension, Saarland University Medical Centre, Kirrberger Strasse, D-66424, Homburg/Saar, Germany. quitscheentchen99@web.de. IN - Beyse, Miriam. Department of Internal Medicine, Nephrology and Hypertension, Saarland University Medical Centre, Kirrberger Strasse, D-66424, Homburg/Saar, Germany. miriam_beyse@web.de. IN - Duerr, Laura. Department of Internal Medicine, Nephrology and Hypertension, Saarland University Medical Centre, Kirrberger Strasse, D-66424, Homburg/Saar, Germany. lau.lau@gmx.net. IN - Gewert, Stella. Department of Internal Medicine, Nephrology and Hypertension, Saarland University Medical Centre, Kirrberger Strasse, D-66424, Homburg/Saar, Germany. stellagewert@googlemail.com. IN - Krauss, Patrizia. Department of Internal Medicine, Nephrology and Hypertension, Saarland University Medical Centre, Kirrberger Strasse, D-66424, Homburg/Saar, Germany. patriziakrauss@arcor.de. IN - Poppleton, Aaron. Department of Internal Medicine, Nephrology and Hypertension, Saarland University Medical Centre, Kirrberger Strasse, D-66424, Homburg/Saar, Germany. aaron.poppleton@gmail.com. IN - Wagenpfeil, Stefan. Institute for Medical Biometry, Epidemiology and applied Medical Informatics, Saarland University Medical Centre, Homburg/Saar, Germany. stefan.wagenpfeil@uks.eu. IN - Fliser, Danilo. Department of Internal Medicine, Nephrology and Hypertension, Saarland University Medical Centre, Kirrberger Strasse, D-66424, Homburg/Saar, Germany. danilo.fliser@uks.eu. IN - Schaefers, Hans-Joachim. Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Centre, Homburg/Saar, Germany. h-j.schaefers@uks.eu. IN - Klingele, Matthias. Department of Internal Medicine, Nephrology and Hypertension, Saarland University Medical Centre, Kirrberger Strasse, D-66424, Homburg/Saar, Germany. matthias.klingele@uks.eu. TI - A single preoperative FGF23 measurement is a strong predictor of outcome in patients undergoing elective cardiac surgery: a prospective observational study. SO - Critical Care (London, England). 19:190, 2015 Apr 23 AS - Crit Care. 19:190, 2015 Apr 23 NJ - Critical care (London, England) PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 9801902 IO - Crit Care PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424828 SB - Index Medicus CP - England MH - Adult MH - Aged MH - Aged, 80 and over MH - Biomarkers/bl [Blood] MH - *Cardiac Surgical Procedures/mo [Mortality] MH - Cardiac Surgical Procedures/td [Trends] MH - Cohort Studies MH - *Elective Surgical Procedures/mo [Mortality] MH - Elective Surgical Procedures/td [Trends] MH - Female MH - *Fibroblast Growth Factors/bl [Blood] MH - Follow-Up Studies MH - Hospital Mortality/td [Trends] MH - Humans MH - Male MH - Middle Aged MH - *Postoperative Complications/bl [Blood] MH - *Postoperative Complications/mo [Mortality] MH - Predictive Value of Tests MH - *Preoperative Care/mt [Methods] MH - Preoperative Care/td [Trends] MH - Prospective Studies MH - Treatment Outcome AB - INTRODUCTION: Several scoring systems have been developed to predict postoperative mortality and complications in patients undergoing cardiac surgery. However, these computer-based calculations are time- and cost-intensive. A simple but highly predictive test for postoperative risk would be of clinical benefit with respect to increasingly scarce hospital resources. We therefore assessed the predictive power of fibroblast growth factor 23 (FGF23) measurement compared with an established scoring system. AB - METHODS: We conducted a prospective interdisciplinary observational study at the Saarland University Medical Centre that included 859 patients undergoing elective cardiac surgery between January 2010 and March 2011 with a median follow-up after discharge of 822 days. We compared a single preoperative measurement of FGF23 as a prognostic tool with the 18 parameters comprising EuroSCORE II with respect to postoperative mortality, acute kidney injury, non-occlusive mesenteric ischemia, clinical course and long-term outcome. AB - RESULTS: Preoperative FGF23 levels were highly predictive of postoperative outcome and complications. The predictive value of FGF23 for mortality in the receiver operating characteristic curve was greater than the EuroSCORE II (area under the curve: 0.800 versus 0.725). Moreover, preoperative FGF23 independently predicted postoperative acute kidney injury and non-occlusive mesenteric ischemia comparably to the EuroSCORE II. Finally, FGF23 was found to be an independent predictor of clinical course parameters, including duration of surgery, ventilation time and length of stay. AB - CONCLUSIONS: In patients undergoing elective cardiac surgery, a simple preoperative FGF23 measurement is a powerful indicator of surgical mortality, postoperative complications and long-term outcome. Its utility compares to the widely used EuroSCORE II. RN - 0 (Biomarkers) RN - 0 (fibroblast growth factor 23) RN - 62031-54-3 (Fibroblast Growth Factors) ES - 1466-609X IL - 1364-8535 DI - 10.1186/s13054-015-0925-6 DO - https://dx.doi.org/10.1186/s13054-015-0925-6 PT - Journal Article PT - Observational Study PT - Research Support, Non-U.S. Gov't ID - 25902817 [pubmed] ID - 10.1186/s13054-015-0925-6 [doi] ID - 10.1186/s13054-015-0925-6 [pii] ID - PMC4424828 [pmc] PP - epublish PH - 2014/08/31 [received] PH - 2015/04/14 [accepted] LG - English EP - 20150423 DP - 2015 Apr 23 DC - 20150509 EZ - 2015/04/24 06:00 DA - 2016/02/13 06:00 DT - 2015/04/24 06:00 YR - 2015 ED - 20160212 RD - 20150511 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25902817 <136. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26076180 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Curro G AU - La Malfa G AU - Lazzara S AU - Caizzone A AU - Fortugno A AU - Navarra G FA - Curro, Giuseppe FA - La Malfa, Giuseppe FA - Lazzara, Salvatore FA - Caizzone, Antonio FA - Fortugno, Anna FA - Navarra, Giuseppe IN - Curro, Giuseppe. Department of Human Pathology, University Hospital of Messina , Messina, Italy . IN - La Malfa, Giuseppe. Department of Human Pathology, University Hospital of Messina , Messina, Italy . IN - Lazzara, Salvatore. Department of Human Pathology, University Hospital of Messina , Messina, Italy . IN - Caizzone, Antonio. Department of Human Pathology, University Hospital of Messina , Messina, Italy . IN - Fortugno, Anna. Department of Human Pathology, University Hospital of Messina , Messina, Italy . IN - Navarra, Giuseppe. Department of Human Pathology, University Hospital of Messina , Messina, Italy . TI - Three-Dimensional Versus Two-Dimensional Laparoscopic Cholecystectomy: Is Surgeon Experience Relevant?. SO - Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A. 25(7):566-70, 2015 Jul AS - J Laparoendosc Adv Surg Tech A. 25(7):566-70, 2015 Jul NJ - Journal of laparoendoscopic & advanced surgical techniques. Part A PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 9706293, c0d IO - J Laparoendosc Adv Surg Tech A SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Attitude of Health Personnel MH - *Cholecystectomy, Laparoscopic/is [Instrumentation] MH - *Clinical Competence MH - Depth Perception MH - Elective Surgical Procedures/is [Instrumentation] MH - Female MH - Humans MH - *Imaging, Three-Dimensional MH - Male MH - Middle Aged MH - *Operative Time MH - Prospective Studies AB - BACKGROUND: A prospective randomized comparison of three-dimensional (3D) versus two-dimensional (2D) imaging during elective laparoscopic cholecystectomy (LC), both performed separately by an advanced laparoscopic surgeon and by a surgeon experienced in open surgical procedures but a novice at laparoscopic procedures, was designed to address the issue of whether 3D systems offer real operative time advantages to this laparoscopic procedure. AB - PATIENTS AND METHODS: Eighty patients were randomized the day of surgery by random computer-generated allocation list to receive either a 3D or 2D high-definition imaging system LC by two surgeons with differing experience. After the insertion of the access ports the surgical procedure was divided in two component tasks. Operative times of the two component tasks and the entire procedure were recorded. AB - RESULTS: The execution times for the two component tasks and the entire procedure were not significantly different between the 2D and 3D groups for the experienced laparoscopic surgeon. However, the execution times for the two component tasks and the entire procedure were significantly faster during 3D compared with 2D for the novice surgeon. Both surgeons experienced better depth perception with the 3D system and subjectively reported less strain using 3D rather than 2D vision. AB - CONCLUSIONS: 3D imaging seems not to influence the performance time of LC by an experienced laparoscopic surgeon. Less experienced laparoscopic surgeons could benefit from shorter performance time with 3D imaging due to no need to adapt to 2D vision. Further comparative studies are necessary to verify on great numbers of cases whether 3D can reduce intraoperative complications such as biliary lesions. ES - 1557-9034 IL - 1092-6429 DO - https://dx.doi.org/10.1089/lap.2014.0641 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 26076180 [pubmed] ID - 10.1089/lap.2014.0641 [doi] PP - ppublish LG - English EP - 20150615 DP - 2015 Jul DC - 20150703 EZ - 2015/06/16 06:00 DA - 2016/02/09 06:00 DT - 2015/06/16 06:00 YR - 2015 ED - 20160208 RD - 20150703 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26076180 <137. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26056753 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hutchins J AU - Delaney D AU - Vogel RI AU - Ghebre RG AU - Downs LS Jr AU - Carson L AU - Mullany S AU - Teoh D AU - Geller MA FA - Hutchins, Jacob FA - Delaney, Daniel FA - Vogel, Rachel Isaksson FA - Ghebre, Rahel G FA - Downs, Levi S Jr FA - Carson, Linda FA - Mullany, Sally FA - Teoh, Deanna FA - Geller, Melissa A IN - Hutchins, Jacob. Department of Anesthesiology, University of Minnesota, Minneapolis, MN, USA. IN - Delaney, Daniel. Department of Anesthesiology, University of Minnesota, Minneapolis, MN, USA. IN - Vogel, Rachel Isaksson. Masonic Cancer Center Biostatistics and Bioinformatics, University of Minnesota, Minneapolis, MN, USA. IN - Ghebre, Rahel G. Department of Obstetrics, Gynecology and Women's Health, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, MN, USA. IN - Downs, Levi S Jr. Department of Obstetrics, Gynecology and Women's Health, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, MN, USA. IN - Carson, Linda. Department of Obstetrics, Gynecology and Women's Health, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, MN, USA. IN - Mullany, Sally. Department of Obstetrics, Gynecology and Women's Health, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, MN, USA. IN - Teoh, Deanna. Department of Obstetrics, Gynecology and Women's Health, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, MN, USA. IN - Geller, Melissa A. Department of Obstetrics, Gynecology and Women's Health, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, MN, USA. Electronic address: gelle005@umn.edu. TI - Ultrasound guided subcostal transversus abdominis plane (TAP) infiltration with liposomal bupivacaine for patients undergoing robotic assisted hysterectomy: A prospective randomized controlled study. SO - Gynecologic Oncology. 138(3):609-13, 2015 Sep AS - Gynecol Oncol. 138(3):609-13, 2015 Sep NJ - Gynecologic oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - fxc, 0365304 IO - Gynecol. Oncol. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592282 OI - Source: NLM. NIHMS724196 SB - Index Medicus CP - United States MH - *Abdominal Muscles/su [Surgery] MH - *Anesthetics, Local/ad [Administration & Dosage] MH - *Bupivacaine/ad [Administration & Dosage] MH - Female MH - Humans MH - *Hysterectomy/mt [Methods] MH - Liposomes/ad [Administration & Dosage] MH - Middle Aged MH - *Nerve Block/mt [Methods] MH - Pain, Postoperative/pc [Prevention & Control] MH - Prospective Studies MH - Robotic Surgical Procedures/mt [Methods] MH - *Ultrasonography, Interventional/mt [Methods] KW - Acute pain; Hysterectomy; Liposomal bupivacaine; Post-operative pain; Robotic; Transversus abdominis plane AB - INTRODUCTION: Optimal pain control after major surgery contributes to a patient's recovery and satisfaction. The use of liposomal bupivacaine in subcostal transversus abdominis plane (TAP) blocks for postoperative pain control after robot assisted abdominal surgery has yet to be studied. AB - METHODS: We conducted a prospective randomized controlled observer-blinded study comparing bilateral subcostal TAP blocks with bupivacaine to bilateral subcostal TAP blocks with liposomal bupivacaine. These were performed prior to the patient undergoing robot assisted hysterectomy. The patients' pain scores, opioid use, side effects, and satisfaction were followed for 72h after injection. AB - RESULTS: Total opioid use in the first 72h after injection was significantly decreased in the group that received liposomal bupivacaine compared to bupivacaine. Patients in the liposomal bupivacaine group had significantly lower maximal pain scores at all time periods studied as well as decreased incidence of nausea/vomiting. There was a trend toward decreased length of stay in the liposomal bupivacaine group. AB - CONCLUSION: Subcostal TAP blocks with liposomal bupivacaine decreased the total opioid requirement for the first 72h after robot assisted hysterectomy when compared to subcostal TAP blocks with bupivacaine. AB - Copyright © 2015 Elsevier Inc. All rights reserved. RN - 0 (Anesthetics, Local) RN - 0 (Liposomes) RN - Y8335394RO (Bupivacaine) ES - 1095-6859 IL - 0090-8258 DI - S0090-8258(15)30029-9 DO - https://dx.doi.org/10.1016/j.ygyno.2015.06.008 PT - Journal Article PT - Randomized Controlled Trial ID - 26056753 [pubmed] ID - S0090-8258(15)30029-9 [pii] ID - 10.1016/j.ygyno.2015.06.008 [doi] ID - PMC4592282 [pmc] ID - NIHMS724196 [mid] PP - ppublish PH - 2015/05/01 [received] PH - 2015/06/04 [revised] PH - 2015/06/05 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT02289079 SA - ClinicalTrials.gov/NCT02289079 SL - https://clinicaltrials.gov/search/term=NCT02289079 SL - https://clinicaltrials.gov/search/term=NCT02289079 GI - No: P30 CA077598 Organization: (CA) *NCI NIH HHS* Country: United States No: UL1 TR000114 Organization: (TR) *NCATS NIH HHS* Country: United States LG - English EP - 20150606 DP - 2015 Sep DC - 20150831 EZ - 2015/06/10 06:00 DA - 2016/02/02 06:00 DT - 2015/06/10 06:00 YR - 2015 ED - 20160201 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26056753 <138. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26056753 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hutchins J AU - Delaney D AU - Vogel RI AU - Ghebre RG AU - Downs LS Jr AU - Carson L AU - Mullany S AU - Teoh D AU - Geller MA FA - Hutchins, Jacob FA - Delaney, Daniel FA - Vogel, Rachel Isaksson FA - Ghebre, Rahel G FA - Downs, Levi S Jr FA - Carson, Linda FA - Mullany, Sally FA - Teoh, Deanna FA - Geller, Melissa A IN - Hutchins, Jacob. Department of Anesthesiology, University of Minnesota, Minneapolis, MN, USA. IN - Delaney, Daniel. Department of Anesthesiology, University of Minnesota, Minneapolis, MN, USA. IN - Vogel, Rachel Isaksson. Masonic Cancer Center Biostatistics and Bioinformatics, University of Minnesota, Minneapolis, MN, USA. IN - Ghebre, Rahel G. Department of Obstetrics, Gynecology and Women's Health, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, MN, USA. IN - Downs, Levi S Jr. Department of Obstetrics, Gynecology and Women's Health, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, MN, USA. IN - Carson, Linda. Department of Obstetrics, Gynecology and Women's Health, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, MN, USA. IN - Mullany, Sally. Department of Obstetrics, Gynecology and Women's Health, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, MN, USA. IN - Teoh, Deanna. Department of Obstetrics, Gynecology and Women's Health, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, MN, USA. IN - Geller, Melissa A. Department of Obstetrics, Gynecology and Women's Health, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, MN, USA. Electronic address: gelle005@umn.edu. TI - Ultrasound guided subcostal transversus abdominis plane (TAP) infiltration with liposomal bupivacaine for patients undergoing robotic assisted hysterectomy: A prospective randomized controlled study. SO - Gynecologic Oncology. 138(3):609-13, 2015 Sep AS - Gynecol Oncol. 138(3):609-13, 2015 Sep NJ - Gynecologic oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - fxc, 0365304 IO - Gynecol. Oncol. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592282 OI - Source: NLM. NIHMS724196 SB - Index Medicus CP - United States MH - *Abdominal Muscles/su [Surgery] MH - *Anesthetics, Local/ad [Administration & Dosage] MH - *Bupivacaine/ad [Administration & Dosage] MH - Female MH - Humans MH - *Hysterectomy/mt [Methods] MH - Liposomes/ad [Administration & Dosage] MH - Middle Aged MH - *Nerve Block/mt [Methods] MH - Pain, Postoperative/pc [Prevention & Control] MH - Prospective Studies MH - Robotic Surgical Procedures/mt [Methods] MH - *Ultrasonography, Interventional/mt [Methods] KW - Acute pain; Hysterectomy; Liposomal bupivacaine; Post-operative pain; Robotic; Transversus abdominis plane AB - INTRODUCTION: Optimal pain control after major surgery contributes to a patient's recovery and satisfaction. The use of liposomal bupivacaine in subcostal transversus abdominis plane (TAP) blocks for postoperative pain control after robot assisted abdominal surgery has yet to be studied. AB - METHODS: We conducted a prospective randomized controlled observer-blinded study comparing bilateral subcostal TAP blocks with bupivacaine to bilateral subcostal TAP blocks with liposomal bupivacaine. These were performed prior to the patient undergoing robot assisted hysterectomy. The patients' pain scores, opioid use, side effects, and satisfaction were followed for 72h after injection. AB - RESULTS: Total opioid use in the first 72h after injection was significantly decreased in the group that received liposomal bupivacaine compared to bupivacaine. Patients in the liposomal bupivacaine group had significantly lower maximal pain scores at all time periods studied as well as decreased incidence of nausea/vomiting. There was a trend toward decreased length of stay in the liposomal bupivacaine group. AB - CONCLUSION: Subcostal TAP blocks with liposomal bupivacaine decreased the total opioid requirement for the first 72h after robot assisted hysterectomy when compared to subcostal TAP blocks with bupivacaine. AB - Copyright © 2015 Elsevier Inc. All rights reserved. RN - 0 (Anesthetics, Local) RN - 0 (Liposomes) RN - Y8335394RO (Bupivacaine) ES - 1095-6859 IL - 0090-8258 DI - S0090-8258(15)30029-9 DO - https://dx.doi.org/10.1016/j.ygyno.2015.06.008 PT - Journal Article PT - Randomized Controlled Trial ID - 26056753 [pubmed] ID - S0090-8258(15)30029-9 [pii] ID - 10.1016/j.ygyno.2015.06.008 [doi] ID - PMC4592282 [pmc] ID - NIHMS724196 [mid] PP - ppublish PH - 2015/05/01 [received] PH - 2015/06/04 [revised] PH - 2015/06/05 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT02289079 SL - https://clinicaltrials.gov/search/term=NCT02289079 GI - No: P30 CA077598 Organization: (CA) *NCI NIH HHS* Country: United States No: UL1 TR000114 Organization: (TR) *NCATS NIH HHS* Country: United States LG - English EP - 20150606 DP - 2015 Sep DC - 20150831 EZ - 2015/06/10 06:00 DA - 2016/02/02 06:00 DT - 2015/06/10 06:00 YR - 2015 ED - 20160201 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=26056753 <139. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25980394 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Rettenmaier MA AU - Abaid LN AU - Brown JV 3rd AU - Mendivil AA AU - Lopez KL AU - Goldstein BH FA - Rettenmaier, Mark A FA - Abaid, Lisa N FA - Brown, John V 3rd FA - Mendivil, Alberto A FA - Lopez, Katrina L FA - Goldstein, Bram H IN - Rettenmaier, Mark A. Gynecologic Oncology Associates, 351 Hospital Road, Suite #507, Newport Beach, CA 92663, United States. IN - Abaid, Lisa N. Gynecologic Oncology Associates, 351 Hospital Road, Suite #507, Newport Beach, CA 92663, United States. IN - Brown, John V 3rd. Gynecologic Oncology Associates, 351 Hospital Road, Suite #507, Newport Beach, CA 92663, United States. IN - Mendivil, Alberto A. Gynecologic Oncology Associates, 351 Hospital Road, Suite #507, Newport Beach, CA 92663, United States. IN - Lopez, Katrina L. Nancy Yeary Women's Cancer Research Foundation, Newport Beach, CA 92663, United States. IN - Goldstein, Bram H. Gynecologic Oncology Associates, 351 Hospital Road, Suite #507, Newport Beach, CA 92663, United States. Electronic address: bram@gynoncology.com. TI - Dramatically reduced incidence of vaginal cuff dehiscence in gynecologic patients undergoing endoscopic closure with barbed sutures: A retrospective cohort study. SO - International Journal Of Surgery. 19:27-30, 2015 Jul AS - Int J Surg. 19:27-30, 2015 Jul NJ - International journal of surgery (London, England) PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101228232 IO - Int J Surg SB - Index Medicus CP - England MH - Adult MH - Aged MH - Female MH - Humans MH - Hysterectomy/ae [Adverse Effects] MH - *Hysterectomy/mt [Methods] MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy/mt [Methods] MH - Middle Aged MH - Polyglactin 910 MH - Retrospective Studies MH - Robotics/mt [Methods] MH - *Surgical Wound Dehiscence/pc [Prevention & Control] MH - *Suture Techniques MH - *Sutures MH - Treatment Outcome KW - Barbed suture; Endoscopic surgery; Vaginal cuff dehiscence; Vicryl suture AB - INTRODUCTION: This retrospective study documented the rate of vaginal cuff dehiscence (VCD) in a large series of gynecologic patients who were treated with an endoscopic (robotic-assisted or laparoscopic) hysterectomy that incorporated either delayed absorbable monofilament barbed or vicryl running sutures. AB - METHOD: We sought to discern any prognostic associations between operative variables (e.g., closure type (barbed or vicryl sutures), endoscopic approach (robotic-assisted or laparoscopic), and energy source (Harmonic Ace Shears or monopolar/bipolar electro-surgery)) and the risk for VCD via patient chart review. Statistical evaluation was comprised of univariate analyses and multiple regression. AB - RESULTS: We identified 1876 subjects; there were 14 cases (0% with barbed suture and 0.99% with vicryl suture) of VCD (an overall incidence of 0.75%), nearly all of which were associated with a robotic-assisted hysterectomy involving vicryl sutures (p = 0.034). However, the type of endoscopic surgery (P = 0.11) and energy source (P = 0.28) were not significant prognostic factors. The VCD patients' exhibited a median duration of 47 days (range, 14-116) until the development of their condition. AB - CONCLUSION: Vaginal cuff separation subsequent to laparoscopic closure is a rare occurrence. While our incidence of VCD was low and comparable to other reported rates in the literature, we did not observe any cases of VCD following laparoscopic hysterectomy performed with barbed suture closure. AB - Copyright © 2015 IJS Publishing Group Limited. Published by Elsevier Ltd. All rights reserved. RN - 34346-01-5 (Polyglactin 910) ES - 1743-9159 IL - 1743-9159 DI - S1743-9191(15)00218-6 DO - https://dx.doi.org/10.1016/j.ijsu.2015.05.007 PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 25980394 [pubmed] ID - S1743-9191(15)00218-6 [pii] ID - 10.1016/j.ijsu.2015.05.007 [doi] PP - ppublish PH - 2015/04/20 [received] PH - 2015/04/29 [revised] PH - 2015/05/04 [accepted] LG - English EP - 20150514 DP - 2015 Jul DC - 20150703 EZ - 2015/05/19 06:00 DA - 2016/01/29 06:00 DT - 2015/05/20 06:00 YR - 2015 ED - 20160128 RD - 20150703 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25980394 <140. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25695457 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lai CS AU - Chen IC AU - Liu SA AU - Lu CT AU - Yen JH AU - Song DY FA - Lai, Chih-Sheng FA - Chen, I-Chen FA - Liu, Shih-An FA - Lu, Chen-Te FA - Yen, Jung-Hsing FA - Song, Ding-Yu IN - Lai, Chih-Sheng. From the *Division of Plastic and Reconstructive Surgery, Department of Surgery, Taichung Veterans General Hospital, Taiwan, ROC, and +Division of Otolaryngology, Taichung Veterans General Hospital, Taiwan, ROC. TI - Robot-assisted free flap reconstruction of oropharyngeal cancer--a preliminary report. SO - Annals of Plastic Surgery. 74 Suppl 2:S105-8, 2015 May AS - Ann Plast Surg. 74 Suppl 2:S105-8, 2015 May NJ - Annals of plastic surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 5vb, 7805336 IO - Ann Plast Surg SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Female MH - *Free Tissue Flaps MH - Humans MH - Male MH - Middle Aged MH - *Oropharyngeal Neoplasms/su [Surgery] MH - *Oropharynx/su [Surgery] MH - *Robotic Surgical Procedures AB - BACKGROUND: The robotic surgical system provides a clear, magnified, 3-dimensional (3D) view as well as a precise and stable instrumental movement, which minimizes many technical difficulties that may be encountered in the surgical treatment of oropharyngeal tumors. A preliminary result of transoral robot-assisted free flap reconstruction of oropharyngeal cancer is presented herein. AB - MATERIALS AND METHODS: Between May and December 2013, the Da Vinci Surgical System (Da Vinci Si, Intuitive Surgical, Sunnyvale, CA) was used in 5 (4 men and 1 woman) cases of oropharyngeal reconstruction. Robot-assisted reconstruction was performed for inset of the flap and for performing a venous anastomosis of the free radial forearm fasciocutaneous flap. AB - RESULTS: All of the reconstructive surgeries were successful without flap failure or take-backs. There were no wound infections or fistulas. AB - CONCLUSION: The application of a robotic surgical system seems to be a safe option in the free flap reconstruction of oropharyngeal defects without lip or mandible splitting. ES - 1536-3708 IL - 0148-7043 DO - https://dx.doi.org/10.1097/SAP.0000000000000464 PT - Clinical Study PT - Journal Article ID - 25695457 [pubmed] ID - 10.1097/SAP.0000000000000464 [doi] PP - ppublish LG - English DP - 2015 May DC - 20150417 EZ - 2015/02/20 06:00 DA - 2016/01/23 06:00 DT - 2015/02/20 06:00 YR - 2015 ED - 20160121 RD - 20150417 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25695457 <141. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26469925 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Seo H AU - Kong YG AU - Jin SJ AU - Chin JH AU - Kim HY AU - Lee YK AU - Hwang JH AU - Kim YK FA - Seo, Hyungseok FA - Kong, Yu-Gyeong FA - Jin, Seok-Joon FA - Chin, Ji-Hyun FA - Kim, Hee-Yeong FA - Lee, Yoon-Kyung FA - Hwang, Jai-Hyun FA - Kim, Young-Kug IN - Seo, Hyungseok. From the Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Republic of Korea (HS); Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea (Y-GK, S-JJ, J-HC, J-HH, Y-KK); and Department of Anesthesiology and Pain Medicine, Hangang Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea (H-YK, Y-KL). TI - Dynamic Arterial Elastance in Predicting Arterial Pressure Increase After Fluid Challenge During Robot-Assisted Laparoscopic Prostatectomy: A Prospective Observational Study. SO - Medicine. 94(41):e1794, 2015 Oct AS - Medicine (Baltimore). 94(41):e1794, 2015 Oct NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616778 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - *Arterial Pressure/ph [Physiology] MH - Fluid Therapy MH - Head-Down Tilt MH - Hemodynamics/ph [Physiology] MH - Humans MH - *Laparoscopy MH - Male MH - Middle Aged MH - Monitoring, Physiologic MH - Pneumoperitoneum, Artificial MH - *Prostatectomy/mt [Methods] MH - *Robotics MH - Stroke Volume AB - During robot-assisted laparoscopic prostatectomy, specific physiological conditions such as carbon dioxide insufflation and the steep Trendelenburg position can alter the cardiac workload and cerebral hemodynamics. Inadequate arterial blood pressure is associated with hypoperfusion, organ damage, and poor outcomes. Dynamic arterial elastance (Ea) has been proposed to be a useful index of fluid management in hypotensive patients. We therefore evaluated whether dynamic Ea can predict a mean arterial pressure (MAP) increase > 15% after fluid challenge during pneumoperitoneum and the steep Trendelenburg position.We enrolled 39 patients receiving robot-assisted laparoscopic prostatectomy. Fluid challenge was performed with 500 mL colloids in the presence of preload-dependent conditions and arterial hypotension. Patients were classified as arterial pressure responders or arterial pressure nonresponders according to whether they showed an MAP increase >15% after fluid challenge. Dynamic Ea was defined as the ratio between the pulse pressure variation and stroke volume variation. Receiver operating characteristic curve analysis was performed to assess the arterial pressure responsiveness after fluid challenge during robot-assisted laparoscopic prostatectomy.Of the 39 patients, 17 were arterial pressure responders and 22 were arterial pressure nonresponders. The mean dynamic Ea before fluid challenge was significantly higher in arterial pressure responders than in arterial pressure nonresponders (0.79 vs 0.61, P < 0.001). In receiver operating characteristic curve analysis, dynamic Ea showed an area under the curve of 0.810. The optimal cut-off value of dynamic Ea for predicting an MAP increase of > 15% after fluid challenge was 0.74.Dynamic Ea can predict an MAP increase > 15% after fluid challenge during robot-assisted laparoscopic prostatectomy. This result suggests that evaluation of arterial pressure responsiveness using dynamic Ea helps to maintain an adequate arterial blood pressure and to improve perioperative outcomes in preload-dependent patients receiving robot-assisted laparoscopic prostatectomy under pneumoperitoneum and in the steep Trendelenburg position. ES - 1536-5964 IL - 0025-7974 DI - 00005792-201510020-00037 DO - https://dx.doi.org/10.1097/MD.0000000000001794 PT - Journal Article ID - 26469925 [pubmed] ID - 10.1097/MD.0000000000001794 [doi] ID - 00005792-201510020-00037 [pii] ID - PMC4616778 [pmc] PP - ppublish LG - English DP - 2015 Oct DC - 20151016 EZ - 2015/10/16 06:00 DA - 2016/01/20 06:00 DT - 2015/10/16 06:00 YR - 2015 ED - 20160119 RD - 20151028 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26469925 <142. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26190391 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Yang M AU - Wu Y AU - Wang G AU - Xiao C AU - Zhang H AU - Gao C FA - Yang, Ming FA - Wu, Yang FA - Wang, Gang FA - Xiao, Cangsong FA - Zhang, Huajun FA - Gao, Changqing IN - Yang, Ming. Department of Cardiovascular Surgery, Institute of Cardiac Surgery, PLA General Hospital, Beijing, China. IN - Wu, Yang. Department of Cardiovascular Surgery, Institute of Cardiac Surgery, PLA General Hospital, Beijing, China. IN - Wang, Gang. Department of Cardiovascular Surgery, Institute of Cardiac Surgery, PLA General Hospital, Beijing, China. IN - Xiao, Cangsong. Department of Cardiovascular Surgery, Institute of Cardiac Surgery, PLA General Hospital, Beijing, China. IN - Zhang, Huajun. Department of Cardiovascular Surgery, Institute of Cardiac Surgery, PLA General Hospital, Beijing, China. IN - Gao, Changqing. Department of Cardiovascular Surgery, Institute of Cardiac Surgery, PLA General Hospital, Beijing, China. Electronic address: gaochq301@yahoo.com. TI - Robotic Total Arterial Off-Pump Coronary Artery Bypass Grafting: Seven-Year Single-Center Experience and Long-Term Follow-Up of Graft Patency. SO - Annals of Thoracic Surgery. 100(4):1367-73, 2015 Oct AS - Ann Thorac Surg. 100(4):1367-73, 2015 Oct NJ - The Annals of thoracic surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 15030100R IO - Ann. Thorac. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - Netherlands MH - *Coronary Artery Bypass, Off-Pump/mt [Methods] MH - *Coronary Artery Disease/su [Surgery] MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - *Robotic Surgical Procedures MH - Time Factors MH - Vascular Patency AB - BACKGROUND: Coronary artery bypass grafting (CABG) is the gold-standard treatment for coronary artery disease, but the long-term benefits of robotic CABG remain unclear. AB - METHODS: Between January 2007 and November 2014, 240 consecutive patients (187 male and 53 female, average age 59 years) underwent robotic off-pump CABG with the da Vinci Surgical System (Intuitive Surgical, Sunnyvale, CA) in our center. Totally endoscopic coronary artery bypass (TECAB) (n = 100) or mini-thoracotomy coronary artery bypass (MINICAB) (n = 140) grafting was performed with skeletonized internal mammary arteries (IMA). Patients were followed up and graft patency was assessed every 6 months by coronary angiography or 64-multi-slide computed tomographic angiography. AB - RESULTS: All cases were completed without conversion to median sternotomy or cardiopulmonary bypass. A total of 237 single IMA grafts (98.3%) and 4 bilateral IMA grafts (1.7%) were used. No operative mortality was observed. Hybrid revascularization of non-left anterior descending vessels was performed in 24 patients (10%). No death, stroke, or myocardial infarction occurred in the follow-up of 41.1 +/- 12.9 months. All grafts were patent before discharge. The IMA graft patency was 97.1% in TECAB and 96.4 % in MINICAB over 3 years (up to 91 months) postoperatively. AB - CONCLUSIONS: Robotic off-pump CABG using IMA grafts is a safe and effective procedure in selected patients. The long-term outcome and patency of IMA grafts are excellent. AB - Copyright © 2015 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved. ES - 1552-6259 IL - 0003-4975 DI - S0003-4975(15)00680-3 DO - https://dx.doi.org/10.1016/j.athoracsur.2015.04.054 PT - Clinical Study PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 26190391 [pubmed] ID - S0003-4975(15)00680-3 [pii] ID - 10.1016/j.athoracsur.2015.04.054 [doi] PP - ppublish PH - 2015/02/16 [received] PH - 2015/04/13 [revised] PH - 2015/04/15 [accepted] LG - English EP - 20150717 DP - 2015 Oct DC - 20151005 EZ - 2015/07/21 06:00 DA - 2016/01/16 06:00 DT - 2015/07/21 06:00 YR - 2015 ED - 20160115 RD - 20151005 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26190391 <143. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25906167 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Taketani Y AU - Mayama C AU - Suzuki N AU - Wada A AU - Oka T AU - Inamochi K AU - Nomoto Y FA - Taketani, Yukako FA - Mayama, Chihiro FA - Suzuki, Noriyuki FA - Wada, Akiko FA - Oka, Tatsuhiro FA - Inamochi, Kazuya FA - Nomoto, Yohei IN - Taketani, Yukako. Department of Ophthalmology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan; Department of Ophthalmology, Asahi General Hospital, Chiba, Japan. IN - Mayama, Chihiro. Department of Ophthalmology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan. IN - Suzuki, Noriyuki. Department of Urology, Asahi General Hospital, Chiba, Japan. IN - Wada, Akiko. Department of Anesthesiology, Asahi General Hospital, Chiba, Japan. IN - Oka, Tatsuhiro. Department of Anesthesiology, Asahi General Hospital, Chiba, Japan. IN - Inamochi, Kazuya. Department of Ophthalmology, Asahi General Hospital, Chiba, Japan; Department of Ophthalmology, Tokyo Metropolitan Police Hospital, Tokyo, Japan. IN - Nomoto, Yohei. Department of Ophthalmology, Asahi General Hospital, Chiba, Japan. TI - Transient but significant visual field defects after robot-assisted laparoscopic radical prostatectomy in deep tRendelenburg position. SO - PLoS ONE [Electronic Resource]. 10(4):e0123361, 2015 AS - PLoS ONE. 10(4):e0123361, 2015 NJ - PloS one PI - Journal available in: Electronic-eCollection PI - Citation processed from: Internet JC - 101285081 IO - PLoS ONE PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408044 SB - Index Medicus CP - United States MH - Humans MH - *Patient Positioning MH - Prospective Studies MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - *Robotics MH - *Visual Fields AB - BACKGROUND: Robot-assisted laparoscopic radical prostatectomy (RALP) is a minimally invasive surgical procedure for prostate cancer. During RALP, the patient must be in a steep Trendelenburg (head-down) position, which leads to a significant increase in intraocular pressure (IOP). The association of RALP with visual field sensitivity, however, has not been prospectively studied. The purpose of this study was to evaluate prospectively the visual field, retinal nerve fiber layer (RNFL) thickness, and optic disc morphology in 50 normal eyes of 25 male patients that underwent RALP. AB - METHODS: The subjects were 25 males among 33 consecutive patients who underwent uneventful RALP under general anesthesia in our hospital. Visual field tests using the Humphrey visual field analyzer 30-2 SITA-standard program were performed before, 7 days after, and 1-3 months after RALP. IOP was measured before, during, and after RALP; and ophthalmologic examinations, including slit-lamp, fundus examination, and optical coherence tomography (OCT), were scheduled before and 7 days after surgery. AB - RESULTS: IOP was significantly increased during RALP up to 29.4 mmHg (P<0.01). Postoperative local visual field defects were detected in 7 eyes of 7 subjects dominantly in the lower hemifield without abnormal findings in the optic nerve head or retina, and the visual field recovered to normal within 3 months after surgery. General factors associated with RALP, IOP, RNFL thickness, or optic disc parameters did not differ significantly between eyes with and without postoperative visual field defects, and parameters of OCT measurements were not altered after surgery. AB - CONCLUSION: Transient but significant unilateral visual field defects were found in 28% of the subjects examined. The probable cause are the increased IOP and altered perfusion during surgery and ophthalmologic examinations are therefore suggested before and after RALP. ES - 1932-6203 IL - 1932-6203 DI - PONE-D-14-53315 DO - https://dx.doi.org/10.1371/journal.pone.0123361 PT - Clinical Trial PT - Journal Article ID - 25906167 [pubmed] ID - 10.1371/journal.pone.0123361 [doi] ID - PONE-D-14-53315 [pii] ID - PMC4408044 [pmc] PP - epublish PH - 2014/12/02 [received] PH - 2015/03/03 [accepted] LG - English EP - 20150423 DP - 2015 DC - 20150424 EZ - 2015/04/24 06:00 DA - 2016/01/15 06:00 DT - 2015/04/24 06:00 YR - 2015 ED - 20160114 RD - 20150505 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25906167 <144. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26254170 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Alenizi AM AU - Bienz M AU - Rajih E AU - Alesawi A AU - Al-Hathal N AU - Benayoun S AU - Lebeau T AU - Zorn KC AU - El-Hakim A FA - Alenizi, Abdullah M FA - Bienz, Marc FA - Rajih, Emad FA - Alesawi, Anwar FA - Al-Hathal, Naif FA - Benayoun, Serge FA - Lebeau, Thierry FA - Zorn, Kevin C FA - El-Hakim, Assaad IN - Alenizi, Abdullah M. Division of Robotic Urology, Department of Surgery, Hopital Sacre Coeur de Montreal, Universite de Montreal, Montreal, Quebec, Canada. IN - Bienz, Marc. Division of Robotic Urology, Department of Surgery, Hopital Sacre Coeur de Montreal, Universite de Montreal, Montreal, Quebec, Canada. IN - Rajih, Emad. Division of Robotic Urology, Department of Surgery, Hopital Sacre Coeur de Montreal, Universite de Montreal, Montreal, Quebec, Canada. IN - Alesawi, Anwar. Division of Robotic Urology, Department of Surgery, Hopital Sacre Coeur de Montreal, Universite de Montreal, Montreal, Quebec, Canada. IN - Al-Hathal, Naif. Division of Robotic Urology, Department of Surgery, Hopital Sacre Coeur de Montreal, Universite de Montreal, Montreal, Quebec, Canada. IN - Benayoun, Serge. Division of Robotic Urology, Department of Surgery, Hopital Sacre Coeur de Montreal, Universite de Montreal, Montreal, Quebec, Canada. IN - Lebeau, Thierry. Division of Robotic Urology, Department of Surgery, Hopital Sacre Coeur de Montreal, Universite de Montreal, Montreal, Quebec, Canada. IN - Zorn, Kevin C. Division of Robotic Urology, Department of Surgery, Hopital Sacre Coeur de Montreal, Universite de Montreal, Montreal, Quebec, Canada. IN - El-Hakim, Assaad. Division of Robotic Urology, Department of Surgery, Hopital Sacre Coeur de Montreal, Universite de Montreal, Montreal, Quebec, Canada. Electronic address: Assaad.elhakim@gmail.com. TI - Uroflow Stop Test and Potency Recovery: A Surrogate for Pelvic Floor Integrity Post Robotic-Assisted Radical Prostatectomy?. SO - Urology. 86(4):766-71, 2015 Oct AS - Urology. 86(4):766-71, 2015 Oct NJ - Urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Aged MH - Erectile Dysfunction/et [Etiology] MH - Erectile Dysfunction/pp [Physiopathology] MH - *Erectile Dysfunction/rh [Rehabilitation] MH - Humans MH - Male MH - Middle Aged MH - *Pelvic Floor/pp [Physiopathology] MH - *Penile Erection/ph [Physiology] MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - Prostatic Diseases/co [Complications] MH - Prostatic Diseases/pp [Physiopathology] MH - *Prostatic Diseases/su [Surgery] MH - Recovery of Function/ph [Physiology] MH - *Robotics MH - Treatment Outcome MH - *Urination/ph [Physiology] AB - OBJECTIVE: To study the relation between uroflow Stop Test and early recovery of potency following robot-assisted radical prostatectomy (RARP). We recently showed that the ability to completely stop urine flow during voiding, measured objectively by uroflowmetry at the time of catheter removal (uroflow Stop Test) can predict early urinary continence recovery following RARP. AB - MATERIALS AND METHODS: In this prospective observational cohort, data were collected on 108 patients operated by a single surgeon (AEH). Eighty patients had a positive uroflow Stop Test (group one) and 28 had a negative Stop Test (group two). Patients were followed for a minimum of 2 years. Covariates included age, body mass index, international prostate symptom score and sexual health inventory for men scores, prostate-specific antigen, tumor stage, prostate volume, nerve sparing status, and estimated blood loss. AB - RESULTS: Preoperative characteristics were comparable between both groups except nerve sparing and prostate-specific antigen which were statistically higher in group one (P <.05). Early 3- and 6-months recovery of erectile function was significantly higher in group one. Potency rates in group one and two at 1, 3, 6, 9, 12, 18, and 24 months were 25% vs 14.3% (P = .241), 54.5% vs 18.5% (P = .001), 55.4% vs 18.5% (P = .001), 56.4% vs 36% (P = .084), 66.6% vs 50% (P = .141), 65.5% vs 56% (P = .404) and 73.2% vs 57.7% (P = .160) respectively. Uroflow Stop Test was independent predictor of early potency recovery on multivariate regression analysis at 6 months [odds ratio 6.042 (confidence interval 95% 1.496-24.413) P = .012]. AB - CONCLUSION: Uroflow Stop Test is simple and can help predict early potency recovery following RARP. AB - Copyright © 2015 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(15)00653-6 DO - https://dx.doi.org/10.1016/j.urology.2015.05.041 PT - Journal Article PT - Observational Study PT - Research Support, Non-U.S. Gov't ID - 26254170 [pubmed] ID - S0090-4295(15)00653-6 [pii] ID - 10.1016/j.urology.2015.05.041 [doi] PP - ppublish PH - 2015/01/13 [received] PH - 2015/04/22 [revised] PH - 2015/05/08 [accepted] LG - English EP - 20150804 DP - 2015 Oct DC - 20151003 EZ - 2015/08/09 06:00 DA - 2016/01/06 06:00 DT - 2015/08/09 06:00 YR - 2015 ED - 20160105 RD - 20151003 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26254170 <145. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25616087 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bahler CD AU - Dube HT AU - Flynn KJ AU - Garg S AU - Monn MF AU - Gutwein LG AU - Mellon MJ AU - Foster RS AU - Cheng L AU - Sandrasegaran MK AU - Sundaram CP FA - Bahler, Clinton D FA - Dube, Hitesh T FA - Flynn, Kevin J FA - Garg, Swapnil FA - Monn, M Francesca FA - Gutwein, Luke G FA - Mellon, Matthew J FA - Foster, Richard S FA - Cheng, Liang FA - Sandrasegaran, M Kumar FA - Sundaram, Chandru P IN - Bahler, Clinton D. 1 Department of Urology, Indiana University , Indianapolis, Indiana. TI - Feasibility of omitting cortical renorrhaphy during robot-assisted partial nephrectomy: a matched analysis. CM - Comment in: J Endourol. 2015 May;29(5):555; PMID: 25625794 CM - Comment in: J Urol. 2015 Oct;194(4):954; PMID: 26382773 SO - Journal of Endourology. 29(5):548-55, 2015 May AS - J Endourol. 29(5):548-55, 2015 May NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - *Blood Loss, Surgical MH - Body Mass Index MH - *Carcinoma, Renal Cell/su [Surgery] MH - Feasibility Studies MH - Female MH - Glomerular Filtration Rate MH - Humans MH - Kidney/pa [Pathology] MH - *Kidney/su [Surgery] MH - *Kidney Neoplasms/su [Surgery] MH - Male MH - Middle Aged MH - Multivariate Analysis MH - *Nephrectomy/mt [Methods] MH - Organ Size MH - *Postoperative Hemorrhage/ep [Epidemiology] MH - Reconstructive Surgical Procedures MH - Retrospective Studies MH - *Robotic Surgical Procedures/mt [Methods] MH - *Suture Techniques MH - Sutures MH - Warm Ischemia MH - Young Adult AB - BACKGROUND AND PURPOSE: To assess the safety of omitting cortical renorrhaphy during robot-assisted partial nephrectomy and measure preliminary functional outcomes. AB - PATIENTS AND METHODS: Fifteen robot-assisted partial nephrectomies were performed with a running, base-layer suture for the collecting system and vessel hemostasis but without cortical renorrhaphy. The nonrenorrhaphy group was matched 1:2 by R.E.N.A.L. nephrometry score to a running, sliding-clip cortical renorrhaphy group retrospectively. Intraoperative blood loss, urine leaks, postoperative bleeds, and functional outcomes were evaluated. Predictors of %volume loss were evaluated using multivariable regression. AB - RESULTS: No differences were seen between renorrhaphy and nonrenorrhaphy in sex (P=0.53), age (P=0.14), body mass index (P=0.08), Charlson score (P=0.44), tumor diameter (P=0.55), nephrometry score (P=0.77), preoperative glomerular filtration rate (GFR, P=0.63), or the amount of resected healthy kidney margin (P=0.21). Warm ischemia time was less for the nonrenorrhaphy group (P<0.002). One pseudoaneurysm necessitating embolization (1/30=3%) was seen in the renorrhaphy group compared with none in the nonrenorrhaphy group. No urine leaks occurred in either group. The median %GFR loss was 8.8% for renorrhaphy and 4.4% for nonrenorrhaphy (P=0.14) at a median follow-up of 4.1 months. The median %volume loss was 17cm(3) for renorrhaphy and 9cm(3) for nonrenorrhaphy (P=0.003). In a multivariable model, both cortical renorrhaphy (P=0.004) and tumor diameter (P=0.004) were predictors of %volume loss. AB - CONCLUSION: Omission of cortical renorrhaphy appears feasible with no urine leaks or bleeding complications observed. The percent renal volume loss was improved by omission of cortical renorrhaphy. Reconstruction technique is important to control for when studying renal function after partial nephrectomy. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2014.0763 PT - Clinical Study PT - Journal Article ID - 25616087 [pubmed] ID - 10.1089/end.2014.0763 [doi] PP - ppublish LG - English EP - 20150310 DP - 2015 May DC - 20150507 EZ - 2015/01/24 06:00 DA - 2015/12/29 06:00 DT - 2015/01/24 06:00 YR - 2015 ED - 20151228 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25616087 <146. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23910728 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Castillo OA AU - Cabrera W AU - Aleman E AU - Vidal-Mora I AU - Yanez R FA - Castillo, O A FA - Cabrera, W FA - Aleman, E FA - Vidal-Mora, I FA - Yanez, R IN - Castillo, O A. Departamento de Urologia y Centro de Cirugia Robotica, Clinica INDISA, Santiago, Chile; Facultad de Medicina, Universidad Andres Bello, Santiago, Chile. Electronic address: octavio.castillo@indisa.cl. IN - Cabrera, W. Departamento de Urologia y Centro de Cirugia Robotica, Clinica INDISA, Santiago, Chile. IN - Aleman, E. Departamento de Urologia y Centro de Cirugia Robotica, Clinica INDISA, Santiago, Chile. IN - Vidal-Mora, I. Departamento de Urologia y Centro de Cirugia Robotica, Clinica INDISA, Santiago, Chile. IN - Yanez, R. Departamento de Urologia y Centro de Cirugia Robotica, Clinica INDISA, Santiago, Chile. TI - Laparoscopic pyeloplasty: technique and results in 80 consecutive patients. SO - Actas Urologicas Espanolas. 38(2):103-8, 2014 Mar AS - Actas Urol Esp. 38(2):103-8, 2014 Mar NJ - Actas urologicas espanolas PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 2a1, 7704993 IO - Actas Urol Esp SB - Index Medicus CP - Spain MH - Adolescent MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - Female MH - Humans MH - *Hydronephrosis/cn [Congenital] MH - Hydronephrosis/su [Surgery] MH - *Kidney Pelvis/su [Surgery] MH - *Laparoscopy MH - Male MH - Middle Aged MH - *Multicystic Dysplastic Kidney/su [Surgery] MH - Time Factors MH - Treatment Outcome MH - *Ureteral Obstruction/su [Surgery] MH - Urologic Surgical Procedures/mt [Methods] MH - Young Adult KW - Anderson-Hynes; Cirugia robotica; Estenosis pieloureteral; Laparoscopia; Laparoscopy; Pieloplastia; Pyeloplasty; Robotic surgery; Ureteropelvic junction obstruction AB - OBJECTIVE: To present our long-term results with the Anderson-Hynes laparoscopic pyeloplasty, performed by a single surgeon. AB - MATERIAL AND METHODS: Between August 1999 and December 2009, 79 patients (80 procedures) were operated for primary ureteropelvic junction obstruction. We use the Anderson-Hynes technique by a transperitoneal approach. Patients were evaluated with Ultrasound, Excretory urography and dynamic renal scintigraphy (Mag-3). The perioperative characteristics, complications and results were reviewed. AB - RESULTS: We performed 80 laparoscopic pyeloplasties in 79 patients. Mean operative time was 93.2 minutes (60-180). Crossing vessels were found in 38 of 82 (46.3%) renal units. Kidney abnormalities occurred in 4 patients (1 double ureteropelvic system, one associated retrocaval ureter, 1 horseshoe kidney and one pelvic kidney). Complications occurred in 5 procedures (6.5%): an immediately postoperative bleeding (Clavien 3b), 1 cecal volvulus (Clavien 3b), 1 urosepsis (Clavien 4th) and 1 urinary fistula (Clavien 3a). In this series there was neither mortality nor conversion to open surgery There was recurrence in 3 out of 80 patients (3.7%). They were resolved as follows: 1 percutaneous antegrade endopyelotomy, 1 secondary laparoscopic pyeloplasty and 1 robotic pyeloplasty. There was a 96.3%. of primary overall success rate. AB - CONCLUSIONS: Our results show that laparoscopic pyeloplasty compares favorably with the result achieved by open surgery. We believe that laparoscopic pyeloplasty is a good surgical alternative for the management of primary ureteropelvic junction obstruction. AB - Copyright © 2013 AEU. Published by Elsevier Espana. All rights reserved. RS - Multicystic renal dysplasia, bilateral ES - 1699-7980 IL - 0210-4806 DI - S0210-4806(13)00210-6 DO - https://dx.doi.org/10.1016/j.acuro.2013.04.010 PT - Clinical Study PT - Journal Article ID - 23910728 [pubmed] ID - S0210-4806(13)00210-6 [pii] ID - 10.1016/j.acuro.2013.04.010 [doi] PP - ppublish PH - 2013/03/05 [received] PH - 2013/04/12 [accepted] LG - English LG - Spanish EP - 20130801 DP - 2014 Mar DC - 20140225 EZ - 2013/08/06 06:00 DA - 2015/12/29 06:00 DT - 2013/08/06 06:00 YR - 2014 ED - 20151228 RD - 20140225 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23910728 <147. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25858419 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Gill IS AU - Metcalfe C AU - Abreu A AU - Duddalwar V AU - Chopra S AU - Cunningham M AU - Thangathurai D AU - Ukimura O AU - Satkunasivam R AU - Hung A AU - Papalia R AU - Aron M AU - Desai M AU - Gallucci M FA - Gill, Inderbir S FA - Metcalfe, Charles FA - Abreu, Andre FA - Duddalwar, Vinay FA - Chopra, Sameer FA - Cunningham, Mark FA - Thangathurai, Duraiyah FA - Ukimura, Osamu FA - Satkunasivam, Raj FA - Hung, Andrew FA - Papalia, Rocco FA - Aron, Monish FA - Desai, Mihir FA - Gallucci, Michele IN - Gill, Inderbir S. USC Institute of Urology, Departments of Urology, Radiology, Anesthesia & Cardiac Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Urology, Regena Elena Cancer Center, Rome, Italy. Electronic address: gillindy@gmail.com. IN - Metcalfe, Charles. USC Institute of Urology, Departments of Urology, Radiology, Anesthesia & Cardiac Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Urology, Regena Elena Cancer Center, Rome, Italy. IN - Abreu, Andre. USC Institute of Urology, Departments of Urology, Radiology, Anesthesia & Cardiac Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Urology, Regena Elena Cancer Center, Rome, Italy. IN - Duddalwar, Vinay. USC Institute of Urology, Departments of Urology, Radiology, Anesthesia & Cardiac Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Urology, Regena Elena Cancer Center, Rome, Italy. IN - Chopra, Sameer. USC Institute of Urology, Departments of Urology, Radiology, Anesthesia & Cardiac Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Urology, Regena Elena Cancer Center, Rome, Italy. IN - Cunningham, Mark. USC Institute of Urology, Departments of Urology, Radiology, Anesthesia & Cardiac Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Urology, Regena Elena Cancer Center, Rome, Italy. IN - Thangathurai, Duraiyah. USC Institute of Urology, Departments of Urology, Radiology, Anesthesia & Cardiac Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Urology, Regena Elena Cancer Center, Rome, Italy. IN - Ukimura, Osamu. USC Institute of Urology, Departments of Urology, Radiology, Anesthesia & Cardiac Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Urology, Regena Elena Cancer Center, Rome, Italy. IN - Satkunasivam, Raj. USC Institute of Urology, Departments of Urology, Radiology, Anesthesia & Cardiac Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Urology, Regena Elena Cancer Center, Rome, Italy. IN - Hung, Andrew. USC Institute of Urology, Departments of Urology, Radiology, Anesthesia & Cardiac Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Urology, Regena Elena Cancer Center, Rome, Italy. IN - Papalia, Rocco. USC Institute of Urology, Departments of Urology, Radiology, Anesthesia & Cardiac Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Urology, Regena Elena Cancer Center, Rome, Italy. IN - Aron, Monish. USC Institute of Urology, Departments of Urology, Radiology, Anesthesia & Cardiac Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Urology, Regena Elena Cancer Center, Rome, Italy. IN - Desai, Mihir. USC Institute of Urology, Departments of Urology, Radiology, Anesthesia & Cardiac Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Urology, Regena Elena Cancer Center, Rome, Italy. IN - Gallucci, Michele. USC Institute of Urology, Departments of Urology, Radiology, Anesthesia & Cardiac Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Urology, Regena Elena Cancer Center, Rome, Italy. TI - Robotic Level III Inferior Vena Cava Tumor Thrombectomy: Initial Series. CM - Comment in: J Urol. 2015 Oct;194(4):937; discussion 937-8; PMID: 26193057 SO - Journal of Urology. 194(4):929-38, 2015 Oct AS - J Urol. 194(4):929-38, 2015 Oct NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - *Carcinoma, Renal Cell/sc [Secondary] MH - *Carcinoma, Renal Cell/su [Surgery] MH - Female MH - Humans MH - Kidney Neoplasms/pa [Pathology] MH - Male MH - Middle Aged MH - *Neoplastic Cells, Circulating MH - *Robotic Surgical Procedures MH - *Thrombectomy/mt [Methods] MH - *Vena Cava, Inferior KW - inferior; robotics; thrombectomy; vena cava AB - PURPOSE: Level III inferior vena cava tumor thrombectomy for renal cancer is one of the most challenging open urologic oncology surgeries. We present the initial series of completely intracorporeal robotic level III inferior vena cava tumor thrombectomy. AB - MATERIALS AND METHODS: Nine patients underwent robotic level III inferior vena cava thrombectomy and 7 patients underwent level II thrombectomy. The entire operation (high intrahepatic inferior vena cava control, caval exclusion, tumor thrombectomy, inferior vena cava repair, radical nephrectomy, retroperitoneal lymphadenectomy) was performed exclusively robotically. To minimize the chances of intraoperative inferior vena cava thrombus embolization, an "inferior vena cava-first, kidney-last" robotic technique was developed. Data were accrued prospectively. AB - RESULTS: All 16 robotic procedures were successful, without open conversion or mortality. For level III cases (9), median primary kidney (right 6, left 3) cancer size was 8.5 cm (range 5.3 to 10.8) and inferior vena cava thrombus length was 5.7 cm (range 4 to 7). Median operative time was 4.9 hours (range 4.5 to 6.3), estimated blood loss was 375 cc (range 200 to 7,000) and hospital stay was 4.5 days. All surgical margins were negative. There were no intraoperative complications and 1 postoperative complication (Clavien 3b). At a median 7 months of followup (range 1 to 18) all patients are alive. Compared to level II thrombi the level III cohort trended toward greater inferior vena cava thrombus length (3.3 vs 5.7 cm), operative time (4.5 vs 4.9 hours) and blood loss (290 vs 375 cc). AB - CONCLUSIONS: With appropriate patient selection, surgical planning and robotic experience, completely intracorporeal robotic level III inferior vena cava thrombectomy is feasible and can be performed efficiently. Larger experience, longer followup and comparison with open surgery are needed to confirm these initial outcomes. AB - Copyright © 2015 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(15)03694-0 DO - https://dx.doi.org/10.1016/j.juro.2015.03.119 PT - Clinical Study PT - Journal Article ID - 25858419 [pubmed] ID - S0022-5347(15)03694-0 [pii] ID - 10.1016/j.juro.2015.03.119 [doi] PP - ppublish PH - 2015/03/31 [accepted] LG - English EP - 20150406 DP - 2015 Oct DC - 20150919 EZ - 2015/04/11 06:00 DA - 2015/12/19 06:00 DT - 2015/04/11 06:00 YR - 2015 ED - 20151217 RD - 20150919 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25858419 <148. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25308968 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Wallerstedt A AU - Tyritzis SI AU - Thorsteinsdottir T AU - Carlsson S AU - Stranne J AU - Gustafsson O AU - Hugosson J AU - Bjartell A AU - Wilderang U AU - Wiklund NP AU - Steineck G AU - Haglind E AU - LAPPRO steering committee FA - Wallerstedt, Anna FA - Tyritzis, Stavros I FA - Thorsteinsdottir, Thordis FA - Carlsson, Stefan FA - Stranne, Johan FA - Gustafsson, Ove FA - Hugosson, Jonas FA - Bjartell, Anders FA - Wilderang, Ulrica FA - Wiklund, N Peter FA - Steineck, Gunnar FA - Haglind, Eva FA - LAPPRO steering committee IN - Wallerstedt, Anna. Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institutet, Solna, Stockholm, Sweden. Electronic address: anna.wallerstedt@karolinska.se. IN - Tyritzis, Stavros I. Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institutet, Solna, Stockholm, Sweden. IN - Thorsteinsdottir, Thordis. Division of Clinical Cancer Epidemiology, Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden; Faculty of Nursing, School of Health Sciences, University of Iceland, Reykjavik, Iceland. IN - Carlsson, Stefan. Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institutet, Solna, Stockholm, Sweden. IN - Stranne, Johan. Department of Urology, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden. IN - Gustafsson, Ove. Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Solna, Stockholm, Sweden. IN - Hugosson, Jonas. Department of Urology, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden. IN - Bjartell, Anders. Department of Urology, Skane University Hospital, Lund University, Lund, Sweden. IN - Wilderang, Ulrica. Division of Clinical Cancer Epidemiology, Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden. IN - Wiklund, N Peter. Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institutet, Solna, Stockholm, Sweden. IN - Steineck, Gunnar. Division of Clinical Cancer Epidemiology, Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden; Department of Oncology and Pathology, Division of Clinical Cancer Epidemiology, Karolinska Institutet, Solna, Stockholm, Sweden. IN - Haglind, Eva. Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden. IR - Anderberg B IR - Bjorholt I IR - Jiborn T IR - Damber JE IR - Khatami A IR - Wulkner-Sylme M IR - Edlund C IR - Pileblad E IR - Boman H IR - Bratt O IR - Westlund U TI - Short-term results after robot-assisted laparoscopic radical prostatectomy compared to open radical prostatectomy. CM - Comment in: Eur Urol. 2015 Apr;67(4):671-2; PMID: 25466941 SO - European Urology. 67(4):660-70, 2015 Apr AS - Eur Urol. 67(4):660-70, 2015 Apr NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Aged MH - Humans MH - *Laparoscopy/is [Instrumentation] MH - Laparoscopy/mt [Methods] MH - Length of Stay/sn [Statistics & Numerical Data] MH - *Lymph Node Excision/mt [Methods] MH - Male MH - Middle Aged MH - Odds Ratio MH - Prospective Studies MH - Prostate/pa [Pathology] MH - *Prostate/su [Surgery] MH - *Prostatectomy/is [Instrumentation] MH - Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Regression Analysis MH - Reoperation/sn [Statistics & Numerical Data] MH - *Robotics/is [Instrumentation] MH - Time Factors MH - Treatment Outcome KW - Complications; Open; Radical prostatectomy; Robot-assisted; Short-term results AB - BACKGROUND: Robot-assisted laparoscopic radical prostatectomy has become a widespread technique despite a lack of randomised trials showing its superiority over open radical prostatectomy. AB - OBJECTIVE: To compare in-hospital characteristics and patient-reported outcomes at 3 mo between robot-assisted laparoscopic and open retropubic radical prostatectomy. AB - DESIGN, SETTING, AND PARTICIPANTS: A prospective, controlled trial was performed of all men who underwent radical prostatectomy at 14 participating centres. Validated patient questionnaires were collected at baseline and after 3 mo by independent health-care researchers. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: The difference in outcome between the two treatment groups were analysed using logistic regression analysis, with adjustment for identified confounders. AB - RESULTS AND LIMITATIONS: Questionnaires were received from 2506 (95%) patients. The robot-assisted surgery group had less perioperative bleeding (185 vs 683 ml, p<0.001) and shorter hospital stay (3.3 vs 4.1 d, p<0.001) than the open surgery group. Operating time was shorter with the open technique (103 vs 175 min, p<0.001) compared with the robot-assisted technique. Reoperation during initial hospital stay was more frequent after open surgery after adjusting for tumour characteristics and lymph node dissection (1.6% vs 0.7%, odds ratio [OR] 0.31, 95% confidence interval [CI 95%] 0.11-0.90). Men who underwent open surgery were more likely to seek healthcare (for one or more of 22 specified disorders identified prestudy) compared to men in the robot-assisted surgery group (p=0.03). It was more common to seek healthcare for cardiovascular reasons in the open surgery group than in the robot-assisted surgery group, after adjusting for nontumour and tumour-specific confounders, (7.9% vs 5.8%, OR 0.63, CI 95% 0.42-0.94). The readmittance rate was not statistically different between the groups. A limitation of the study is the lack of a standardised tool for the assessment of the adverse events. AB - CONCLUSIONS: This large prospective study confirms previous findings that robot-assisted laparoscopic radical prostatectomy is a safe procedure with some short-term advantages compared to open surgery. Whether these advantages also include long-term morbidity and are related to acceptable costs remain to be studied. AB - PATIENT SUMMARY: We compare patient-reported outcomes between two commonly used surgical techniques. Our results show that the choice of surgical technique may influence short-term outcomes. AB - Copyright © 2014 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(14)00973-7 DO - https://dx.doi.org/10.1016/j.eururo.2014.09.036 PT - Controlled Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 25308968 [pubmed] ID - S0302-2838(14)00973-7 [pii] ID - 10.1016/j.eururo.2014.09.036 [doi] PP - ppublish PH - 2014/07/09 [received] PH - 2014/09/23 [accepted] LG - English EP - 20141011 DP - 2015 Apr DC - 20150313 EZ - 2014/10/14 06:00 DA - 2015/12/19 06:00 DT - 2014/10/14 06:00 YR - 2015 ED - 20151217 RD - 20150313 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25308968 <149. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26200539 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Dal Moro F AU - Crestani A AU - Valotto C AU - Guttilla A AU - Soncin R AU - Mangano A AU - Zattoni F FA - Dal Moro, Fabrizio FA - Crestani, Alessandro FA - Valotto, Claudio FA - Guttilla, Andrea FA - Soncin, Rodolfo FA - Mangano, Angelo FA - Zattoni, Filiberto IN - Dal Moro, Fabrizio. Department of Surgical, Oncological and Gastroenterological Sciences Urology, University of Padova, Italy. IN - Crestani, Alessandro. Department of Surgical, Oncological and Gastroenterological Sciences Urology, University of Padova, Italy. IN - Valotto, Claudio. Department of Surgical, Oncological and Gastroenterological Sciences Urology, University of Padova, Italy. IN - Guttilla, Andrea. Department of Surgical, Oncological and Gastroenterological Sciences Urology, University of Padova, Italy. IN - Soncin, Rodolfo. Department of Surgical, Oncological and Gastroenterological Sciences Urology, University of Padova, Italy. IN - Mangano, Angelo. Department of Anesthesiology, Azienda Ospedaliera di Padova, Padova, Italy. IN - Zattoni, Filiberto. Department of Surgical, Oncological and Gastroenterological Sciences Urology, University of Padova, Italy. TI - Anesthesiologic effects of transperitoneal versus extraperitoneal approach during robot-assisted radical prostatectomy: results of a prospective randomized study. SO - International Braz J Urol. 41(3):466-72, 2015 May-Jun AS - Int Braz J Urol. 41(3):466-72, 2015 May-Jun NJ - International braz j urol : official journal of the Brazilian Society of Urology PI - Journal available in: Print PI - Citation processed from: Internet JC - 101158091 IO - Int Braz J Urol PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752139 SB - Index Medicus CP - Brazil MH - Aged MH - *Anesthesia, Inhalation/mt [Methods] MH - Animals MH - *Carbon Dioxide/me [Metabolism] MH - *Hemodynamics/de [Drug Effects] MH - Humans MH - Male MH - Middle Aged MH - Neoplasm Grading MH - Operative Time MH - Peritoneum/su [Surgery] MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Reproducibility of Results MH - Risk Factors MH - *Robotic Surgical Procedures/mt [Methods] MH - Statistics, Nonparametric MH - Time Factors MH - Treatment Outcome AB - OBJECTIVES: To compare the effects of CO(2) insufflation on hemodynamics and oxygen levels and on acid-base level during Robot-Assisted Radical Prostatectomy (RARP) with transperitoneal (TP) versus extra-peritoneal (EP) accesses. AB - MATERIALS AND METHODS: Sixty-two patients were randomly assigned to TP (32) and EP (30) to RARP. Pre-operation data were collected for all patients. Hemodynamic, respiratory and blood acid-base parameters were measured at the moment of induction of anesthesia (T0), after starting CO(2) insufflation (T1), and at 60 (T2) and 120 minutes (T3) after insufflation. In all cases, the abdominal pressure was set at 15 mmHg. Complications were reported according to the Clavien-Dindo classification. Student's two-t-test, with a significance level set at p<0.05, was used to compare categorical values between groups. The Mann-Whitney U-test was used to compare the median values of two nonparametric continuous variables. AB - RESULTS: The demographic characteristics of the patients in both groups were statistically comparable. Analysis of intra-operative anesthesiologic parameters showed that partial CO(2) pressure during EP was significantly higher than during TP, with a consequent decrease in arterial pH. Other parameters analysed were similar in the two groups. Postoperative complications were comparable between groups. The most important limitations of this study were the small size of the patient groups and the impossibility of maintaining standard abdominal pressure throughout the operational phases, despite attempts to regulate it. AB - CONCLUSIONS: This prospective randomized study demonstrates that, from the anesthesiologic viewpoint, during RARP the TP approach is preferable to EP, because of lower CO(2) reabsorption and risk of acidosis. RN - 142M471B3J (Carbon Dioxide) ES - 1677-6119 IL - 1677-5538 DI - IBJUv41n3a11 DO - https://dx.doi.org/10.1590/S1677-5538.IBJU.2014.0199 PT - Journal Article PT - Randomized Controlled Trial ID - 26200539 [pubmed] ID - IBJUv41n3a11 [pii] ID - PMC4752139 [pmc] PP - ppublish PH - 2014/04/21 [received] PH - 2014/09/30 [accepted] LG - English DP - 2015 May-Jun DC - 20150723 EZ - 2015/07/23 06:00 DA - 2015/12/17 06:00 DT - 2015/07/23 06:00 YR - 2015 ED - 20151215 RD - 20160512 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26200539 <150. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25417069 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Elli E AU - Gonzalez-Heredia R AU - Sarvepalli S AU - Masrur M FA - Elli, Enrique FA - Gonzalez-Heredia, Raquel FA - Sarvepalli, Shravan FA - Masrur, Mario IN - Elli, Enrique. College of Medicine, University of Illinois at Chicago, 840 South Wood Street, 435 E, Chicago, IL, 60612, USA, eelli@uic.edu. TI - Laparoscopic and robotic sleeve gastrectomy: short- and long-term results. SO - Obesity Surgery. 25(6):967-74, 2015 Jun AS - Obes Surg. 25(6):967-74, 2015 Jun NJ - Obesity surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - c0v, 9106714 IO - Obes Surg SB - Index Medicus CP - United States MH - Adolescent MH - Adult MH - Aged MH - Female MH - *Gastrectomy/mt [Methods] MH - Humans MH - *Laparoscopy/mt [Methods] MH - Length of Stay MH - Male MH - Middle Aged MH - *Obesity, Morbid/su [Surgery] MH - Operative Time MH - *Robotics MH - Treatment Outcome MH - Weight Loss MH - Young Adult AB - INTRODUCTION: Sleeve gastrectomy has gained popularity over the past decade due to its safety, feasibility, and good results. The purpose of this study is to describe our results, both short and long term, with this procedure. AB - MATERIAL AND METHODS: This study is a nonrandomized, controlled, retrospective review of 409 patients who underwent a minimally invasive sleeve gastrectomy at the University of Illinois Hospital and Health System from January 2008 to December 2013. A total of 304 patients underwent a laparoscopic sleeve gastrectomy, and another 105 patients underwent a robotic procedure using the da Vinci Surgical System. Patient demographics, comorbidities, date of surgery, postoperative morbidity and mortality, operating time, length of stay, and excess weight loss were reviewed. AB - RESULTS: The mean age was 41 years (18-70) with no statistical difference between the two groups. Patient's demographics were similar (p=0.395) in both groups. The mean operative time for the robotic group was 110.6 versus 84.18 min in the laparoscopic group, which was statistically significant (p<0.05). There were no significant differences between the two groups with regard to the perioperative complications, length of stay, or % excess weight loss. AB - CONCLUSION: There is no significant difference between the robotic and laparoscopic group in terms of complications, length of stay, and estimated blood loss. Robot-assisted sleeve gastrectomy is associated with longer operative time and increased cost. ES - 1708-0428 IL - 0960-8923 DO - https://dx.doi.org/10.1007/s11695-014-1499-0 PT - Controlled Clinical Trial PT - Journal Article ID - 25417069 [pubmed] ID - 10.1007/s11695-014-1499-0 [doi] PP - ppublish LG - English DP - 2015 Jun DC - 20150508 EZ - 2014/11/24 06:00 DA - 2015/12/15 06:00 DT - 2014/11/25 06:00 YR - 2015 ED - 20151214 RD - 20150508 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25417069 <151. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25432493 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Choi SK AU - Park S AU - Ahn H FA - Choi, Seung-Kwon FA - Park, Sejun FA - Ahn, Hanjong IN - Ahn, Hanjong. Department of Urology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. TI - Randomized clinical trial of a bladder neck plication stitch during robot-assisted radical prostatectomy. SO - Asian Journal of Andrology. 17(2):304-8, 2015 Mar-Apr AS - Asian J Androl. 17(2):304-8, 2015 Mar-Apr NJ - Asian journal of andrology PI - Journal available in: Print PI - Citation processed from: Internet JC - 100942132, dw0 IO - Asian J. Androl. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650455 SB - Index Medicus CP - China MH - Aged MH - Humans MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Postoperative Complications/et [Etiology] MH - Postoperative Complications/su [Surgery] MH - Prospective Studies MH - Prostate/su [Surgery] MH - *Prostatectomy/ae [Adverse Effects] MH - *Prostatic Neoplasms/su [Surgery] MH - Recovery of Function MH - *Robotic Surgical Procedures/ae [Adverse Effects] MH - Time Factors MH - Treatment Outcome MH - *Urinary Incontinence/et [Etiology] MH - *Urinary Incontinence/su [Surgery] MH - *Urologic Surgical Procedures, Male AB - Urinary incontinence after robot-assisted radical prostatectomy (RARP) is one of the most bothersome complications affecting patients' daily lives. The efficacy of the bladder neck plication stitch technique in promoting an earlier return of continence was prospectively evaluated in 158 patients who underwent RARP for clinically localized prostate cancer by a single surgeon at our institute from March 2012 to January 2013. Patients were randomized 1:1 to undergo surgery with (n = 79) or without (n = 79) the bladder neck plication stitch, and their time to recovery from incontinence, defined as being pad free, was compared. Recovery from incontinence at 1, 3, and 6 months were observed in 22 (27.8%), 42 (53.2%), and 57 (72.2%) patients, respectively, treated with, and 23 (29.1%), 47 (59.5%), and 59 (74.7%) patients, respectively, treated without the bladder neck plication stitch, with no significant difference in time to recovery from incontinence between the two groups. Multivariate analysis showed that age, membranous urethral length and shape of the prostatic apex on magnetic resonance imaging were independent predictors of early recovery from urinary incontinence after RARP. The bladder neck plication stitch had no effect on time to recovery from postoperative urinary incontinence following RARP. ES - 1745-7262 IL - 1008-682X DI - 139258 DO - https://dx.doi.org/10.4103/1008-682X.139258 PT - Journal Article PT - Randomized Controlled Trial ID - 25432493 [pubmed] ID - 139258 [pii] ID - 10.4103/1008-682X.139258 [doi] ID - PMC4650455 [pmc] PP - ppublish LG - English DP - 2015 Mar-Apr DC - 20150311 EZ - 2014/11/30 06:00 DA - 2015/12/15 06:00 DT - 2014/11/30 06:00 YR - 2015 ED - 20151207 RD - 20160218 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25432493 <152. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25628104 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hudry D AU - Ahmad S AU - Zanagnolo V AU - Narducci F AU - Fastrez M AU - Ponce J AU - Tucher E AU - Lecuru F AU - Conri V AU - Leguevaque P AU - Goffin F AU - Holloway RW AU - Lambaudie E AU - SERGS Group FA - Hudry, Delphine FA - Ahmad, Sarfraz FA - Zanagnolo, Vanna FA - Narducci, Fabrice FA - Fastrez, Maxime FA - Ponce, Jordi FA - Tucher, Elisabeth FA - Lecuru, Fabrice FA - Conri, Vanessa FA - Leguevaque, Pierre FA - Goffin, Frederic FA - Holloway, Robert W FA - Lambaudie, Eric FA - SERGS Group IN - Hudry, Delphine. *Georges-Francois Leclerc Cancer Center, Dijon, France; +Florida Hospital Cancer Institute, Orlando, FL; ++European Institute of Oncology, Milan, Italy; Centre Oscar Lambret, Lille, France; St Pierre University Hospital, Brussels, Belgium; PUZ Leuven, Leuven, Belgium; #Institute of Oncology, IDIBELL, Idibell, Spain; **Charite University Medicine, Berlin, Germany; ++European Hospital, Paris, France; ++++University Hospital, Bordeaux, France; Claudius Regaud Institute, Toulouse, France; Citadelle Hospital, Liege, Belgium; and PPPaoli Calmettes Institute, Marseille, France. IR - Kholer C IR - Leblanc E IR - Maggioni A IR - Vergote I IR - Houvenaeghel G TI - Robotically assisted para-aortic lymphadenectomy: surgical results: a cohort study of 487 patients. SO - International Journal of Gynecological Cancer. 25(3):504-11, 2015 Mar AS - Int J Gynecol Cancer. 25(3):504-11, 2015 Mar NJ - International journal of gynecological cancer : official journal of the International Gynecological Cancer Society PI - Journal available in: Print PI - Citation processed from: Internet JC - dzp, 9111626 IO - Int. J. Gynecol. Cancer SB - Index Medicus CP - United States MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Aorta MH - Blood Loss, Surgical MH - Blood Transfusion MH - Conversion to Open Surgery MH - Female MH - *Genital Neoplasms, Female/su [Surgery] MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy/mt [Methods] MH - Length of Stay MH - Lymph Node Excision/ae [Adverse Effects] MH - *Lymph Node Excision/mt [Methods] MH - Lymphocele/et [Etiology] MH - Middle Aged MH - Operative Time MH - Retrospective Studies MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures/mt [Methods] MH - Venous Thrombosis/et [Etiology] MH - Young Adult AB - OBJECTIVES: The aim of this study was to evaluate perioperative outcomes of robotic-assisted laparoscopic para-aortic lymphadenectomy (PAL) in patients with gynecologic cancers during the learning phases of robotic surgery programs and to compare results of extraperitoneal versus transperitoneal approaches of PAL. AB - MATERIALS AND METHODS: This study is a retrospective multicentric study of patients who underwent robotically assisted laparoscopic PAL (N = 487). Eleven European centers and 1 US center participated in the study. Abstracted data included age, body mass index, indication, type of surgical approach (transperitoneal or extraperitoneal), associated surgical procedures, operative time, estimated blood loss, lymph node count, hospital length of stay (LOS), and complications. Para-aortic lymphadenectomy was performed by an extraperitoneal approach in 58 cases (12%) and transperitoneal in 429 cases (88%). AB - RESULTS: The mean (SD) para-aortic lymph node count was 12.6 (8.1), operative time was 217 (85) minutes, estimated blood loss was 105 (110) mL, and LOS was 2.8 (3.2) days. Four (0.8%) conversions to open and 2 (0.4%) conversions to laparoscopy were described. There were 32 lymphocysts (6.6%), 3 deep venous thromboses (0.6%), and 10 transfusions (2.1%). For transperitoneal approach, the average number of lymph nodes removed was higher in isolated PAL group than the hysterectomy combined group (report node counts 95% confidence interval, -7.29 to -3.52, P = 1.5 x 10-6). For isolated PAL, the LOS was shorter in the extraperitoneal group than in the transperitoneal group (report data 95% CI, -1.35 to -0.35, P = 0.001). AB - CONCLUSIONS: Robotic-assisted PAL seems safe and feasible. More lymph nodes were removed during an isolated transperitoneal PAL dissection compared with a combined procedure with hysterectomy. Extraperitoneal approach seems attractive relative to transperitoneal dissection, but the superiority of one or the other way is not demonstrated by our study. ES - 1525-1438 IL - 1048-891X DO - https://dx.doi.org/10.1097/IGC.0000000000000373 PT - Comparative Study PT - Journal Article PT - Multicenter Study ID - 25628104 [pubmed] ID - 10.1097/IGC.0000000000000373 [doi] PP - ppublish LG - English DP - 2015 Mar DC - 20150220 EZ - 2015/01/29 06:00 DA - 2015/12/15 06:00 DT - 2015/01/30 06:00 YR - 2015 ED - 20151203 RD - 20150220 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25628104 <153. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25129475 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sofra M AU - Antenucci A AU - Gallucci M AU - Mandoj C AU - Papalia R AU - Claroni C AU - Monteferrante I AU - Torregiani G AU - Gianaroli V AU - Sperduti I AU - Tomao L AU - Forastiere E FA - Sofra, Maria FA - Antenucci, Anna FA - Gallucci, Michele FA - Mandoj, Chiara FA - Papalia, Rocco FA - Claroni, Claudia FA - Monteferrante, Ilaria FA - Torregiani, Giulia FA - Gianaroli, Valeria FA - Sperduti, Isabella FA - Tomao, Luigi FA - Forastiere, Ester IN - Sofra, Maria. Department of Anaesthesiology, Regina Elena, Roma National Cancer Institute, Via Elio Chianesi 53, Roma, 00144, Italy. sofra@ifo.it. IN - Antenucci, Anna. Clinical Pathology, Regina Elena, Roma National Cancer Institute, Rome, Italy. antenucci@ifo.it. IN - Gallucci, Michele. Department of Urology, Regina Elena, Roma National Cancer Institute, Rome, Italy. gallucci@ifo.it. IN - Mandoj, Chiara. Clinical Pathology, Regina Elena, Roma National Cancer Institute, Rome, Italy. conti@ifo.it. IN - Papalia, Rocco. Department of Urology, Regina Elena, Roma National Cancer Institute, Rome, Italy. mpurri@yahoo.it. IN - Claroni, Claudia. Department of Anaesthesiology, Regina Elena, Roma National Cancer Institute, Via Elio Chianesi 53, Roma, 00144, Italy. clacla@fastwebnet.itt. IN - Monteferrante, Ilaria. Department of Anaesthesiology, Regina Elena, Roma National Cancer Institute, Via Elio Chianesi 53, Roma, 00144, Italy. Monteferrante@ifo.it. IN - Torregiani, Giulia. Department of Anaesthesiology, Regina Elena, Roma National Cancer Institute, Via Elio Chianesi 53, Roma, 00144, Italy. giulia.torregiani@tin.it. IN - Gianaroli, Valeria. Department of Anaesthesiology, Regina Elena, Roma National Cancer Institute, Via Elio Chianesi 53, Roma, 00144, Italy. v.gianaroli@gmail.com. IN - Sperduti, Isabella. Division of Biostatistic, Regina Elena, Roma National Cancer Institute, Rome, Italy. sperduti@ifo.it. IN - Tomao, Luigi. Clinical Pathology, Regina Elena, Roma National Cancer Institute, Rome, Italy. luigi.tomao@gmail.com. IN - Forastiere, Ester. Department of Anaesthesiology, Regina Elena, Roma National Cancer Institute, Via Elio Chianesi 53, Roma, 00144, Italy. forastiere@ifo.it. TI - Perioperative changes in pro and anticoagulant factors in prostate cancer patients undergoing laparoscopic and robotic radical prostatectomy with different anaesthetic techniques. SO - Journal of Experimental & Clinical Cancer Research. 33:63, 2014 Aug 17 AS - J Exp Clin Cancer Res. 33:63, 2014 Aug 17 NJ - Journal of experimental & clinical cancer research : CR PI - Journal available in: Electronic PI - Citation processed from: Internet JC - cui, 8308647 IO - J. Exp. Clin. Cancer Res. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431486 SB - Index Medicus CP - England MH - Aged MH - *Anesthesia, Inhalation/ae [Adverse Effects] MH - *Anesthesia, Intravenous/ae [Adverse Effects] MH - *Blood Coagulation Factors/me [Metabolism] MH - Blood Coagulation Tests MH - *Hemostasis MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/is [Instrumentation] MH - *Laparoscopy MH - Male MH - Middle Aged MH - Prostatectomy/ae [Adverse Effects] MH - Prostatectomy/is [Instrumentation] MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/bl [Blood] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Risk Factors MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - Robotic Surgical Procedures/is [Instrumentation] MH - *Robotic Surgical Procedures MH - Rome MH - Thrombosis/bl [Blood] MH - Thrombosis/di [Diagnosis] MH - *Thrombosis/et [Etiology] MH - Time Factors MH - Treatment Outcome AB - BACKGROUND: Laparoscopic prostatectomy (LRP) may activate clotting system influencing the risk of perioperative thrombosis in patients with prostate cancer. Moreover, different anaesthetic techniques can also modify coagulant factors. Thus, the aim of this study was to investigate the effects on pro- and anti-coagulant and fibrinolytic factors of two established types of anaesthesia in patients with prostate cancer undergoing elective LRP. AB - METHODS: 102 patients with primary prostate cancer, who underwent conventional LRP or robot-assisted laparoscopic prostatectomy (RALP), were studied and divided into 2 groups to receive total intravenous anesthesia with target-controlled infusion (TIVA-TCI) or balanced inhalation anaesthesia (BAL) prior to surgery. Before the induction of anaesthesia (T0), 1 hr (T1) and 24 hrs post-surgery (T2), some pro-coagulant factors, fibronolysis markers, p-selectin and haemostatic system inhibitors were evaluated. AB - RESULTS: Both TIVA-TCI and BAL patients showed a marked and significant increase in pro-coagulant factors and consequent reduction in haemostatic system inhibitors in the early post operative period (p<0.004 for each markers). Use of RALP showed a significant increase in prothrombotic markers as compared to LRP. In TIVA patients undergoing LRP, a significant reduction of p-selectin levels between T0 and T2 (p=0.001) was observed as compared to BAL, suggesting a better protective effect on platelet activation of anaesthetic agents used for TIVA. AB - CONCLUSIONS: Both anaesthetic techniques significantly seem to increase the risk of thrombosis in prostate cancer patients undergoing LRP, mainly when the robotic device was utilized, encouraging the use of a peri-operative thromboembolic prophylaxis in these patients. RN - 0 (Blood Coagulation Factors) ES - 1756-9966 IL - 0392-9078 DI - s13046-014-0063-z DO - https://dx.doi.org/10.1186/s13046-014-0063-z PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 25129475 [pubmed] ID - 10.1186/s13046-014-0063-z [doi] ID - s13046-014-0063-z [pii] ID - PMC4431486 [pmc] PP - epublish PH - 2014/04/04 [received] PH - 2014/07/15 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01998685 SA - ClinicalTrials.gov/NCT01998685 SL - https://clinicaltrials.gov/search/term=NCT01998685 SL - https://clinicaltrials.gov/search/term=NCT01998685 LG - English EP - 20140817 DP - 2014 Aug 17 DC - 20150428 EZ - 2014/08/18 06:00 DA - 2015/12/15 06:00 DT - 2014/08/19 06:00 YR - 2014 ED - 20151203 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25129475 <154. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25129475 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sofra M AU - Antenucci A AU - Gallucci M AU - Mandoj C AU - Papalia R AU - Claroni C AU - Monteferrante I AU - Torregiani G AU - Gianaroli V AU - Sperduti I AU - Tomao L AU - Forastiere E FA - Sofra, Maria FA - Antenucci, Anna FA - Gallucci, Michele FA - Mandoj, Chiara FA - Papalia, Rocco FA - Claroni, Claudia FA - Monteferrante, Ilaria FA - Torregiani, Giulia FA - Gianaroli, Valeria FA - Sperduti, Isabella FA - Tomao, Luigi FA - Forastiere, Ester IN - Sofra, Maria. Department of Anaesthesiology, Regina Elena, Roma National Cancer Institute, Via Elio Chianesi 53, Roma, 00144, Italy. sofra@ifo.it. IN - Antenucci, Anna. Clinical Pathology, Regina Elena, Roma National Cancer Institute, Rome, Italy. antenucci@ifo.it. IN - Gallucci, Michele. Department of Urology, Regina Elena, Roma National Cancer Institute, Rome, Italy. gallucci@ifo.it. IN - Mandoj, Chiara. Clinical Pathology, Regina Elena, Roma National Cancer Institute, Rome, Italy. conti@ifo.it. IN - Papalia, Rocco. Department of Urology, Regina Elena, Roma National Cancer Institute, Rome, Italy. mpurri@yahoo.it. IN - Claroni, Claudia. Department of Anaesthesiology, Regina Elena, Roma National Cancer Institute, Via Elio Chianesi 53, Roma, 00144, Italy. clacla@fastwebnet.itt. IN - Monteferrante, Ilaria. Department of Anaesthesiology, Regina Elena, Roma National Cancer Institute, Via Elio Chianesi 53, Roma, 00144, Italy. Monteferrante@ifo.it. IN - Torregiani, Giulia. Department of Anaesthesiology, Regina Elena, Roma National Cancer Institute, Via Elio Chianesi 53, Roma, 00144, Italy. giulia.torregiani@tin.it. IN - Gianaroli, Valeria. Department of Anaesthesiology, Regina Elena, Roma National Cancer Institute, Via Elio Chianesi 53, Roma, 00144, Italy. v.gianaroli@gmail.com. IN - Sperduti, Isabella. Division of Biostatistic, Regina Elena, Roma National Cancer Institute, Rome, Italy. sperduti@ifo.it. IN - Tomao, Luigi. Clinical Pathology, Regina Elena, Roma National Cancer Institute, Rome, Italy. luigi.tomao@gmail.com. IN - Forastiere, Ester. Department of Anaesthesiology, Regina Elena, Roma National Cancer Institute, Via Elio Chianesi 53, Roma, 00144, Italy. forastiere@ifo.it. TI - Perioperative changes in pro and anticoagulant factors in prostate cancer patients undergoing laparoscopic and robotic radical prostatectomy with different anaesthetic techniques. SO - Journal of Experimental & Clinical Cancer Research. 33:63, 2014 Aug 17 AS - J Exp Clin Cancer Res. 33:63, 2014 Aug 17 NJ - Journal of experimental & clinical cancer research : CR PI - Journal available in: Electronic PI - Citation processed from: Internet JC - cui, 8308647 IO - J. Exp. Clin. Cancer Res. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431486 SB - Index Medicus CP - England MH - Aged MH - *Anesthesia, Inhalation/ae [Adverse Effects] MH - *Anesthesia, Intravenous/ae [Adverse Effects] MH - *Blood Coagulation Factors/me [Metabolism] MH - Blood Coagulation Tests MH - *Hemostasis MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/is [Instrumentation] MH - *Laparoscopy MH - Male MH - Middle Aged MH - Prostatectomy/ae [Adverse Effects] MH - Prostatectomy/is [Instrumentation] MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/bl [Blood] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Risk Factors MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - Robotic Surgical Procedures/is [Instrumentation] MH - *Robotic Surgical Procedures MH - Rome MH - Thrombosis/bl [Blood] MH - Thrombosis/di [Diagnosis] MH - *Thrombosis/et [Etiology] MH - Time Factors MH - Treatment Outcome AB - BACKGROUND: Laparoscopic prostatectomy (LRP) may activate clotting system influencing the risk of perioperative thrombosis in patients with prostate cancer. Moreover, different anaesthetic techniques can also modify coagulant factors. Thus, the aim of this study was to investigate the effects on pro- and anti-coagulant and fibrinolytic factors of two established types of anaesthesia in patients with prostate cancer undergoing elective LRP. AB - METHODS: 102 patients with primary prostate cancer, who underwent conventional LRP or robot-assisted laparoscopic prostatectomy (RALP), were studied and divided into 2 groups to receive total intravenous anesthesia with target-controlled infusion (TIVA-TCI) or balanced inhalation anaesthesia (BAL) prior to surgery. Before the induction of anaesthesia (T0), 1 hr (T1) and 24 hrs post-surgery (T2), some pro-coagulant factors, fibronolysis markers, p-selectin and haemostatic system inhibitors were evaluated. AB - RESULTS: Both TIVA-TCI and BAL patients showed a marked and significant increase in pro-coagulant factors and consequent reduction in haemostatic system inhibitors in the early post operative period (p<0.004 for each markers). Use of RALP showed a significant increase in prothrombotic markers as compared to LRP. In TIVA patients undergoing LRP, a significant reduction of p-selectin levels between T0 and T2 (p=0.001) was observed as compared to BAL, suggesting a better protective effect on platelet activation of anaesthetic agents used for TIVA. AB - CONCLUSIONS: Both anaesthetic techniques significantly seem to increase the risk of thrombosis in prostate cancer patients undergoing LRP, mainly when the robotic device was utilized, encouraging the use of a peri-operative thromboembolic prophylaxis in these patients. RN - 0 (Blood Coagulation Factors) ES - 1756-9966 IL - 0392-9078 DI - s13046-014-0063-z DO - https://dx.doi.org/10.1186/s13046-014-0063-z PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 25129475 [pubmed] ID - 10.1186/s13046-014-0063-z [doi] ID - s13046-014-0063-z [pii] ID - PMC4431486 [pmc] PP - epublish PH - 2014/04/04 [received] PH - 2014/07/15 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01998685 SL - https://clinicaltrials.gov/search/term=NCT01998685 LG - English EP - 20140817 DP - 2014 Aug 17 DC - 20150428 EZ - 2014/08/18 06:00 DA - 2015/12/15 06:00 DT - 2014/08/19 06:00 YR - 2014 ED - 20151203 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=25129475 <155. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24582327 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Alemozaffar M AU - Sanda M AU - Yecies D AU - Mucci LA AU - Stampfer MJ AU - Kenfield SA FA - Alemozaffar, Mehrdad FA - Sanda, Martin FA - Yecies, Derek FA - Mucci, Lorelei A FA - Stampfer, Meir J FA - Kenfield, Stacey A IN - Alemozaffar, Mehrdad. USC Institute of Urology, Keck Medical Center at USC, Los Angeles, CA, USA. Electronic address: malemozaffar@gmail.com. IN - Sanda, Martin. Department of Urology, Emory University School of Medicine, Atlanta, GA, USA. IN - Yecies, Derek. Boston University School of Medicine, Boston, MA, USA. IN - Mucci, Lorelei A. Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. IN - Stampfer, Meir J. Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. IN - Kenfield, Stacey A. Department of Urology, University of California, San Francisco, CA, USA. TI - Benchmarks for operative outcomes of robotic and open radical prostatectomy: results from the Health Professionals Follow-up Study. CM - Comment in: Eur Urol. 2015 Mar;67(3):439-40; PMID: 24631405 SO - European Urology. 67(3):432-8, 2015 Mar AS - Eur Urol. 67(3):432-8, 2015 Mar NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128909 OI - Source: NLM. NIHMS571168 SB - Index Medicus CP - Switzerland MH - Aged MH - *Benchmarking/st [Standards] MH - Blood Loss, Surgical/pc [Prevention & Control] MH - Blood Transfusion MH - Disease-Free Survival MH - Follow-Up Studies MH - Health Care Surveys MH - *Health Personnel MH - Humans MH - Kaplan-Meier Estimate MH - Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/mt [Methods] MH - *Laparoscopy/st [Standards] MH - Length of Stay MH - Linear Models MH - Logistic Models MH - Lymph Node Excision/st [Standards] MH - Lymphatic Metastasis MH - Male MH - Multivariate Analysis MH - Postoperative Complications/et [Etiology] MH - *Process Assessment (Health Care)/st [Standards] MH - Prostatectomy/ae [Adverse Effects] MH - Prostatectomy/mt [Methods] MH - *Prostatectomy/st [Standards] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - *Quality Indicators, Health Care/st [Standards] MH - Quality of Life MH - Risk Factors MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - Robotic Surgical Procedures/mt [Methods] MH - *Robotic Surgical Procedures/st [Standards] MH - Surveys and Questionnaires MH - Time Factors MH - Treatment Outcome MH - United States KW - Health-related quality of life; Open; Outcomes; Prostatectomy; Robotic AB - BACKGROUND: Robot-assisted laparoscopic radical prostatectomy (RALP) has become increasingly common; however, there have been no nationwide, population-based, non-claims-based studies to evaluate differences in outcomes between RALP and open radical retropubic prostatectomy (RRP). AB - OBJECTIVE: To determine surgical, oncologic, and health-related quality of life (HRQOL) outcomes following RALP and RRP in a nationwide cohort. AB - DESIGN, SETTING, AND PARTICIPANTS: We identified 903 men in the Health Professionals Follow-up Study diagnosed with prostate cancer between 2000 and 2010 who underwent radical prostatectomy using RALP (n=282) or RRP (n=621) as primary treatment. AB - INTERVENTION: Radical prostatectomy. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: We compared patients undergoing RALP or RRP across a range of perioperative, oncologic, and HRQOL outcomes. AB - RESULTS AND LIMITATIONS: Use of RALP increased during the study period, constituting 85.2% of study subjects in 2009, up from 4.5% in 2003. Patients undergoing RALP compared to RRP were less likely to have a lymph node dissection (51.5% vs 85.4%; p<0.0001), had less blood loss (207.4 ml vs 852.3 ml; p<0.0001), were less likely to receive blood transfusions (4.3% vs 30.3%; p<0.0001), and had shorter hospital stays (1.8 d vs 2.9 d; p<0.0001). Surgical, oncologic, and HRQOL outcomes did not differ significantly among the groups. In multivariate logistic regression models, there were no significant differences in 3- or 5-yr recurrence-free survival comparing RALP versus RRP (hazard ratios: 0.98 [95% confidence interval (CI), 0.46-2.08] and 0.75 [95% CI, 0.18-3.11], respectively). AB - CONCLUSIONS: In a nationwide cohort of patients undergoing surgical treatment for prostate cancer, RALP was associated with shorter hospital stay, and lower blood loss and transfusion rates than RRP. Surgical oncologic and HRQOL outcomes were similar between groups. AB - PATIENT SUMMARY: We studied men throughout the United States with prostate cancer who underwent surgical removal of the prostate. We found that robot-assisted laparoscopic radical prostatectomy resulted in shorter hospital stay, less blood loss, and fewer blood transfusions than radical retropubic prostatectomy. There were no differences in cancer control or health-related quality of life. AB - Copyright © 2014 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(14)00118-3 DO - https://dx.doi.org/10.1016/j.eururo.2014.01.039 PT - Journal Article PT - Observational Study PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't ID - 24582327 [pubmed] ID - S0302-2838(14)00118-3 [pii] ID - 10.1016/j.eururo.2014.01.039 [doi] ID - PMC4128909 [pmc] ID - NIHMS571168 [mid] PP - ppublish PH - 2013/11/18 [received] PH - 2014/01/31 [accepted] GI - No: T32CA009001 Organization: (CA) *NCI NIH HHS* Country: United States No: R01CA141298 Organization: (CA) *NCI NIH HHS* Country: United States No: R25CA098566 Organization: (CA) *NCI NIH HHS* Country: United States No: R25 CA098566 Organization: (CA) *NCI NIH HHS* Country: United States No: T32 CA009001 Organization: (CA) *NCI NIH HHS* Country: United States No: UM1 CA167552 Organization: (CA) *NCI NIH HHS* Country: United States No: R01 CA141298 Organization: (CA) *NCI NIH HHS* Country: United States LG - English EP - 20140211 DP - 2015 Mar DC - 20150312 EZ - 2014/03/04 06:00 DA - 2015/12/15 06:00 DT - 2014/03/04 06:00 YR - 2015 ED - 20151202 RD - 20161019 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24582327 <156. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26251004 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hashoul S AU - Gaspar T AU - Halon DA AU - Lewis BS AU - Shenkar Y AU - Jaffe R AU - Peled N AU - Rubinshtein R FA - Hashoul, Sharbell FA - Gaspar, Tamar FA - Halon, David A FA - Lewis, Basil S FA - Shenkar, Yuval FA - Jaffe, Ronen FA - Peled, Nathan FA - Rubinshtein, Ronen IN - Hashoul, Sharbell. Lady Davis Carmel Medical Center, Technion-Israel Institute of Technology, Haifa, Israel; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. IN - Gaspar, Tamar. Lady Davis Carmel Medical Center, Technion-Israel Institute of Technology, Haifa, Israel; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. IN - Halon, David A. Lady Davis Carmel Medical Center, Technion-Israel Institute of Technology, Haifa, Israel; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. IN - Lewis, Basil S. Lady Davis Carmel Medical Center, Technion-Israel Institute of Technology, Haifa, Israel; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. IN - Shenkar, Yuval. Lady Davis Carmel Medical Center, Technion-Israel Institute of Technology, Haifa, Israel; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. IN - Jaffe, Ronen. Lady Davis Carmel Medical Center, Technion-Israel Institute of Technology, Haifa, Israel; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. IN - Peled, Nathan. Lady Davis Carmel Medical Center, Technion-Israel Institute of Technology, Haifa, Israel; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. IN - Rubinshtein, Ronen. Lady Davis Carmel Medical Center, Technion-Israel Institute of Technology, Haifa, Israel; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. Electronic address: ronenrub@clalit.org.il. TI - Automated Computer-Assisted Diagnosis of Obstructive Coronary Artery Disease in Emergency Department Patients Undergoing 256-Slice Coronary Computed Tomography Angiography for Acute Chest Pain. SO - American Journal of Cardiology. 116(7):1017-21, 2015 Oct 01 AS - Am J Cardiol. 116(7):1017-21, 2015 Oct 01 NJ - The American journal of cardiology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 3dq, 0207277 IO - Am. J. Cardiol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Acute Disease MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - *Chest Pain/dg [Diagnostic Imaging] MH - Chest Pain/et [Etiology] MH - *Coronary Angiography/mt [Methods] MH - Coronary Occlusion/co [Complications] MH - *Coronary Occlusion/dg [Diagnostic Imaging] MH - *Emergency Service, Hospital MH - Feasibility Studies MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - *Multidetector Computed Tomography/mt [Methods] MH - *Pattern Recognition, Automated/mt [Methods] MH - *Radiographic Image Interpretation, Computer-Assisted/mt [Methods] MH - Reproducibility of Results MH - Retrospective Studies MH - Young Adult AB - A 256-slice coronary computed tomography angiography (CCTA) is an accurate method for detection and exclusion of obstructive coronary artery disease (OBS-CAD). However, accurate image interpretation requires expertise and may not be available at all hours. The purpose of this study was to evaluate the usefulness of a fully automated computer-assisted diagnosis (COMP-DIAG) tool for exclusion of OBS-CAD in patients in the emergency department (ED) presenting with chest pain. Three hundred sixty-nine patients in ED without known coronary disease underwent 256-slice CCTA as part of the assessment of chest pain of uncertain origin. COMP-DIAG (CorAnalyzer II) automatically reported presence or exclusion of OBS-CAD (>50% stenosis, >1 vessel). Performance characteristics of COMP-DIAG for exclusion and detection of OBS-CAD were determined using expert reading as the reference standard. Seventeen (5%) studies were unassessable by COMP-DIAG software, and 352 patients (1,056 vessels) were therefore available for analysis. COMP-DIAG identified 33% of assessable studies as having OBS-CAD, but the prevalence of OBS-CAD on CCTA was only 18% (66 of 352 patients) by standard expert reading. However, COMP-DIAG correctly identified 61 of the 66 patients (93%) with OBS-CAD with 21 vessels (2%) with OBS-CAD misclassified as negative. In conclusion, compared to expert reading, automated computer-assisted diagnosis using the CorAnalyzer showed high sensitivity but only moderate specificity for detection of obstructive coronary disease in patients in ED who underwent 256-slice CCTA. The high negative predictive value of this computer-assisted algorithm may be useful in the ED setting. AB - Copyright © 2015 Elsevier Inc. All rights reserved. ES - 1879-1913 IL - 0002-9149 DI - S0002-9149(15)01621-5 DO - https://dx.doi.org/10.1016/j.amjcard.2015.07.014 PT - Journal Article PT - Observational Study ID - 26251004 [pubmed] ID - S0002-9149(15)01621-5 [pii] ID - 10.1016/j.amjcard.2015.07.014 [doi] PP - ppublish PH - 2015/05/12 [received] PH - 2015/07/03 [revised] PH - 2015/07/03 [accepted] LG - English EP - 20150716 DP - 2015 Oct 01 DC - 20150911 EZ - 2015/08/08 06:00 DA - 2015/12/15 06:00 DT - 2015/08/08 06:00 YR - 2015 ED - 20151201 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26251004 <157. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25030478 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Suda K AU - Man-I M AU - Ishida Y AU - Kawamura Y AU - Satoh S AU - Uyama I FA - Suda, Koichi FA - Man-I, Mariko FA - Ishida, Yoshinori FA - Kawamura, Yuichiro FA - Satoh, Seiji FA - Uyama, Ichiro IN - Suda, Koichi. Division of Upper GI, Department of Surgery, Fujita Health University, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan, ko-suda@nifty.com. TI - Potential advantages of robotic radical gastrectomy for gastric adenocarcinoma in comparison with conventional laparoscopic approach: a single institutional retrospective comparative cohort study. SO - Surgical Endoscopy. 29(3):673-85, 2015 Mar AS - Surg Endosc. 29(3):673-85, 2015 Mar NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - *Adenocarcinoma/su [Surgery] MH - Adult MH - Aged MH - Aged, 80 and over MH - Female MH - Follow-Up Studies MH - *Gastrectomy/mt [Methods] MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - Operative Time MH - Retrospective Studies MH - *Robotics/mt [Methods] MH - *Stomach Neoplasms/su [Surgery] MH - Treatment Outcome AB - BACKGROUND: We have previously reported that laparoscopic approach improved short-term postoperative courses even for advanced gastric adenocarcinoma, but not morbidity, in comparison with open approach. The objective of this study was to determine the impact of the use of the surgical robot, da Vinci Surgical System, in minimally invasive radical gastrectomy on short-term outcomes. AB - METHODS: A single institutional retrospective cohort study was performed (UMIN000011749). Five hundred twenty-six patients who underwent radical gastrectomy were enrolled. Eighty-eight patients who agreed to uninsured use of the surgical robot underwent robotic gastrectomy, whereas the remaining 438 patients who wished for laparoscopic (lap) approach with health insurance coverage underwent conventional laparoscopic gastrectomy. AB - RESULTS: In the robotic group, morbidity (robotic vs lap 2.3 vs 11.4 %, p = 0.009) and hospital stay following surgery (robotic vs lap 14 [2-31] vs 15 [8-136] days, p = 0.021) were significantly improved, even though operative time (p = 0.003) and estimated blood loss (p = 0.026) were slightly greater. In particular, local (robotic vs lap 1.1 vs 9.8 %, p = 0.007) rather than systemic (robotic vs lap 1.1 vs 2.5 %, p = 0.376) complication rates were attenuated using the surgical robot. Multivariate analyses revealed that non-use of the surgical robot (OR 6.174 [1.454-26.224], p = 0.014), total gastrectomy (OR 4.670 [2.503-8.713], p < 0.001), and D2 lymphadenectomy (OR 2.095 [1.124-3.903], p = 0.020) were the significant independent risk factors determining postoperative complications. AB - CONCLUSIONS: The use of the surgical robot might reduce surgery-related complications, leading to further improvement in short-term postoperative courses following minimally invasive radical gastrectomy. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-014-3718-0 PT - Comparative Study PT - Journal Article ID - 25030478 [pubmed] ID - 10.1007/s00464-014-3718-0 [doi] PP - ppublish PH - 2014/02/22 [received] PH - 2014/06/25 [accepted] LG - English EP - 20140717 DP - 2015 Mar DC - 20150205 EZ - 2014/07/18 06:00 DA - 2015/11/18 06:00 DT - 2014/07/18 06:00 YR - 2015 ED - 20151117 RD - 20150205 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25030478 <158. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23833240 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Martinez-Maestre MA AU - Gambadauro P AU - Gonzalez-Cejudo C AU - Torrejon R FA - Martinez-Maestre, Maria Angeles FA - Gambadauro, Pietro FA - Gonzalez-Cejudo, Carmen FA - Torrejon, Rafael IN - Martinez-Maestre, Maria Angeles. "Virgen del Rocio" University Hospital, University of Seville, Seville, Spain. IN - Gambadauro, Pietro. "Virgen del Rocio" University Hospital, University of Seville, Seville, Spain Uppsala University Hospital, Uppsala, Sweden gambadauro@gmail.com. IN - Gonzalez-Cejudo, Carmen. "Virgen del Rocio" University Hospital, University of Seville, Seville, Spain. IN - Torrejon, Rafael. "Virgen del Rocio" University Hospital, University of Seville, Seville, Spain. TI - Total laparoscopic hysterectomy with and without robotic assistance: a prospective controlled study. SO - Surgical Innovation. 21(3):250-5, 2014 Jun AS - Surg Innov. 21(3):250-5, 2014 Jun NJ - Surgical innovation PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101233809 IO - Surg Innov SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Female MH - Humans MH - Hysterectomy/ae [Adverse Effects] MH - *Hysterectomy/mt [Methods] MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy/mt [Methods] MH - Length of Stay MH - Middle Aged MH - Operative Time MH - Postoperative Complications MH - Prospective Studies MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures/mt [Methods] MH - Young Adult KW - blood loss; controlled study; operative time; prospective study; robotic hysterectomy; total laparoscopic hysterectomy AB - BACKGROUND: Hysterectomies are very common, and most of them are still performed abdominally. The minimally invasive alternatives are perceived as difficult by gynecologists. Robotic assistance is thought to facilitate laparoscopic surgery. The aim of this study was to compare the surgical outcomes of robotic-assisted and conventional total laparoscopic hysterectomy. AB - METHODS: Patients, candidate to hysterectomy for benign indications, were allocated to either robotic or conventional laparoscopy in a quasi-randomized fashion. Patients were operated following a standardized surgical protocol. Main outcome measures were total surgical time, conversions to laparotomy, blood loss, hospital stay, and complications. AB - RESULTS: Fifty-one patients underwent robotic hysterectomy (mean age = 46.59 years) and 54 conventional laparoscopy (mean age = 50.02 years). The groups were homogeneous in body mass index and uterine weight. Robotic-assisted hysterectomies were significantly shorter (154.63 +/- 36.57 vs 185.65 +/- 42.98 minutes in the control group; P = .0001). Patients in the robotic group also had a significantly smaller reduction in hemoglobin (9.69% +/- 8.88% vs 15.29% +/- 8.39% in controls; P = .0012) and hematocrit (10.56% +/- 8.3% vs 14.89% +/- 8.11%; P = .008). No intraoperative conversions to laparotomy were required. Complication rate was low and similar in both groups. All patients were fully recovered at 1-month follow-up outpatient visit. AB - CONCLUSIONS: Significantly lower operative times and blood loss indicate that robotic assistance can facilitate surgery already during the learning curve period. Nevertheless, proficiency can be reached in conventional laparoscopy through training, and the cost-effectiveness of robotic hysterectomy for benign conditions is yet to be confirmed. AB - Copyright © The Author(s) 2013. ES - 1553-3514 IL - 1553-3506 DI - 1553350613492023 DO - https://dx.doi.org/10.1177/1553350613492023 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 23833240 [pubmed] ID - 1553350613492023 [pii] ID - 10.1177/1553350613492023 [doi] PP - ppublish LG - English EP - 20130705 DP - 2014 Jun DC - 20150408 EZ - 2013/07/09 06:00 DA - 2015/11/18 06:00 DT - 2013/07/09 06:00 YR - 2014 ED - 20151117 RD - 20150408 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23833240 <159. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24688393 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Acar O AU - Esen T AU - Musaoglu A AU - Vural M FA - Acar, Omer FA - Esen, Tarik FA - Musaoglu, Ahmet FA - Vural, Metin IN - Acar, Omer. Department of Urology, VKF American Hospital, 34365 Istanbul, Turkey. IN - Esen, Tarik. Department of Urology, VKF American Hospital, 34365 Istanbul, Turkey ; School of Medicine, Koc University, 34450 Istanbul, Turkey. IN - Musaoglu, Ahmet. Department of Urology, VKF American Hospital, 34365 Istanbul, Turkey. IN - Vural, Metin. Department of Radiology, VKF American Hospital, 34365 Istanbul, Turkey. TI - Do we need to clamp the renal hilum liberally during the initial phase of the learning curve of robot-assisted nephron-sparing surgery?. SO - Thescientificworldjournal. 2014:498917, 2014 AS - ScientificWorldJournal. 2014:498917, 2014 NJ - TheScientificWorldJournal PI - Journal available in: Electronic-eCollection PI - Citation processed from: Internet JC - 101131163 IO - ScientificWorldJournal PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944210 SB - Index Medicus CP - United States MH - Adult MH - Blood Loss, Surgical MH - Female MH - Glomerular Filtration Rate MH - Humans MH - Kidney/bs [Blood Supply] MH - Kidney Neoplasms/pa [Pathology] MH - *Kidney Neoplasms/su [Surgery] MH - Learning Curve MH - Male MH - Middle Aged MH - *Nephrectomy/mt [Methods] MH - *Nephrons/su [Surgery] MH - Operative Time MH - Organ Sparing Treatments/mt [Methods] MH - Postoperative Period MH - Retrospective Studies MH - *Robotic Surgical Procedures/mt [Methods] MH - Treatment Outcome AB - OBJECTIVE: We aimed to compare the results of our initial robot-assisted nephron-sparing surgeries (RANSS) performed with or without hilar clamping. AB - MATERIAL AND METHOD: Charts of the initial RANSSs (n = 44), which were performed by a single surgeon, were retrospectively reviewed. R.E.N.A.L. nephrometry system, modified Clavien classification, and M.D.R.D. equation were used to record tumoral complexity, complications, and estimated glomerular filtration rate (eGFR), respectively. Outcomes of the clamped (group 1, n = 14) versus off-clamp (group 2, n = 30) RANSSs were compared. AB - RESULTS: The difference between the two groups was insignificant regarding mean patient age, mean tumor size, and mean R.E.N.A.L. nephrometry score. Mean operative time, mean estimated blood loss amount, and mean length of hospitalization were similar between groups. A total of 4 patients in each group suffered 11 Clavien grade > 2 complications early postoperatively. Open conversion rates were similar. The difference between the 2 groups in terms of the mean postoperative change in eGFR was insignificant. We did not encounter any local recurrence after a mean follow-up of 18.9 months. AB - CONCLUSIONS: Creating warm-ischemic conditions during RANSS should not be a liberal decision, even in the initial phases of the learning curve for a highly experienced open surgeon. ES - 1537-744X IL - 1537-744X DO - https://dx.doi.org/10.1155/2014/498917 PT - Clinical Trial PT - Journal Article ID - 24688393 [pubmed] ID - 10.1155/2014/498917 [doi] ID - PMC3944210 [pmc] PP - epublish PH - 2013/11/06 [received] PH - 2014/01/02 [accepted] LG - English EP - 20140211 DP - 2014 DC - 20140401 EZ - 2014/04/02 06:00 DA - 2015/11/17 06:00 DT - 2014/04/02 06:00 YR - 2014 ED - 20151116 RD - 20140401 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24688393 <160. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26189333 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Afzal MZ AU - Tobert CM AU - Bulica E AU - Noyes SL AU - Lane BR FA - Afzal, Muhammad Zubair FA - Tobert, Conrad M FA - Bulica, Emi FA - Noyes, Sabrina L FA - Lane, Brian R IN - Afzal, Muhammad Zubair. Division of Urology, Spectrum Health Hospital System, Grand Rapids, MI; Grand Rapids Medical Education Partners, Grand Rapids, MI. IN - Tobert, Conrad M. Grand Rapids Medical Education Partners, Grand Rapids, MI; Department of Surgery, Michigan State University College of Human Medicine, Grand Rapids, MI. IN - Bulica, Emi. Grand Rapids Medical Education Partners, Grand Rapids, MI; Department of Surgery, Michigan State University College of Human Medicine, Grand Rapids, MI. IN - Noyes, Sabrina L. Division of Urology, Spectrum Health Hospital System, Grand Rapids, MI. IN - Lane, Brian R. Division of Urology, Spectrum Health Hospital System, Grand Rapids, MI; Department of Surgery, Michigan State University College of Human Medicine, Grand Rapids, MI. Electronic address: brian.lane@spectrumhealth.org. TI - Modification of Technique for Suprapubic Catheter Placement After Robot-assisted Radical Prostatectomy Reduces Catheter-associated Complications. CM - Comment in: Urology. 2015 Aug;86(2):406; PMID: 26189331 SO - Urology. 86(2):401-6, 2015 Aug AS - Urology. 86(2):401-6, 2015 Aug NJ - Urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Humans MH - Male MH - Middle Aged MH - Postoperative Complications/pc [Prevention & Control] MH - *Prostatectomy/mt [Methods] MH - Retrospective Studies MH - *Robotic Surgical Procedures MH - *Urinary Catheterization/ae [Adverse Effects] MH - *Urinary Catheterization/mt [Methods] MH - Urinary Catheters AB - OBJECTIVE: To compare the outcomes of patients undergoing robot-assisted radical prostatectomy (RARP) with urinary drainage using a modified technique for suprapubic catheter (SPC) placement with those undergoing a previously described technique for SPC placement and those with urethral catheter (UC) alone. AB - MATERIALS AND METHODS: We reviewed the records of 225 consecutive patients who underwent RARP by a single surgeon. The most recent patients were contacted via a telephone survey with 86 responses (69%) received. AB - RESULTS: After RARP, 174 patients had only UC placement (77%) and 51 had an SPC placed (23%). Twelve patients had SPC placement with a 4-mL balloon (SPC-4), with catheter-related complications occurring in four patients (33%). The technique was modified to use SPC with a 10-mL balloon (SPC-10). Only 2 of 39 SPC-10 patients (5%) had catheter-related complications (P = .03 vs SPC-4). Continence rates at 6 weeks were 83% and 82% for UC and SPC, respectively. Based on postoperative survey results using a 10-point scale, overall experience with RARP was rated 8.9 +/- 1.7 and 8.7 +/- 2.3 for UC and SPC, respectively (P = .63). Mean catheter bother was rated 5.1 +/- 3.0 and 4.6 +/- 2.9 for UC and SPC, respectively (P = .45). AB - CONCLUSION: SPC provides a safe option for patients who would prefer not to have UC following RARP, with equivalent perioperative outcomes. Modification of the published technique to place a standard 16F catheter results in fewer catheter-related complications. AB - Copyright © 2015 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(15)00401-X DO - https://dx.doi.org/10.1016/j.urology.2015.02.078 PT - Comparative Study PT - Evaluation Studies PT - Journal Article PT - Observational Study PT - Research Support, Non-U.S. Gov't ID - 26189333 [pubmed] ID - S0090-4295(15)00401-X [pii] ID - 10.1016/j.urology.2015.02.078 [doi] PP - ppublish PH - 2014/11/06 [received] PH - 2015/02/25 [revised] PH - 2015/02/27 [accepted] LG - English EP - 20150716 DP - 2015 Aug DC - 20150824 EZ - 2015/07/21 06:00 DA - 2015/11/13 06:00 DT - 2015/07/21 06:00 YR - 2015 ED - 20151112 RD - 20150824 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26189333 <161. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25137430 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kim NY AU - Yoo YC AU - Park H AU - Choi YD AU - Kim CY AU - Bai SJ FA - Kim, Na Young FA - Yoo, Young-Chul FA - Park, HeeJoon FA - Choi, Young Deuk FA - Kim, Chan Yun FA - Bai, Sun Joon IN - Kim, Na Young. 1 Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine , Seoul, Korea. TI - The effect of dexmedetomidine on intraocular pressure increase in patients during robot-assisted laparoscopic radical prostatectomy in the steep Trendelenburg position. SO - Journal of Endourology. 29(3):310-6, 2015 Mar AS - J Endourol. 29(3):310-6, 2015 Mar NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Anesthesia, General MH - Dexmedetomidine/ad [Administration & Dosage] MH - *Dexmedetomidine/pd [Pharmacology] MH - Female MH - *Head-Down Tilt MH - Humans MH - Hypnotics and Sedatives/ad [Administration & Dosage] MH - *Hypnotics and Sedatives/pd [Pharmacology] MH - Infusions, Intravenous MH - *Intraocular Pressure/de [Drug Effects] MH - Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - *Prostatectomy/mt [Methods] MH - Robotics/mt [Methods] MH - Treatment Outcome AB - PURPOSE: This study was to evaluate the effect of intraoperative continuous infusion of dexmedetomidine on intraocular pressure (IOP) in patients undergoing robot-assisted laparoscopic radical prostatectomy (RALRP) in the steep Trendelenburg (ST). AB - MATERIALS AND METHODS: Sixty-eight patients were randomly divided into two groups. The dexmedetomidine group (Group D, n=34) received a continuous infusion of dexmedetomidine at a rate of 0.4mug kg(-1) hour(-1) from the induction of anesthesia until the end of the ST position, while the control group (Group C, n=34) received an equal volume of physiologic saline at the same rate under conventional general anesthesia with sevoflurane and remifentanil. IOP was measured at 11 predefined time points for all patients. AB - RESULTS: Significant differences in IOP were detected between the two groups by a linear mixed model analysis (p<0.001). The highest mean IOP was 19.9+/-5.0mm Hg in Group D and 25.7+/-5.0mm Hg in Group C; both were measured 60 minutes after the patients had been placed in the ST position. No significant between-group differences in ocular perfusion pressure, mean blood pressure, or heart rate were observed between the two groups. No ocular or other complications were noted. AB - CONCLUSION: Intraoperative continuous infusion of dexmedetomidine may help alleviate IOP increase in patients undergoing RALRP in the ST position. RN - 0 (Hypnotics and Sedatives) RN - 67VB76HONO (Dexmedetomidine) ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2014.0381 PT - Journal Article PT - Randomized Controlled Trial ID - 25137430 [pubmed] ID - 10.1089/end.2014.0381 [doi] PP - ppublish LG - English EP - 20141014 DP - 2015 Mar DC - 20150305 EZ - 2014/08/20 06:00 DA - 2015/10/27 06:00 DT - 2014/08/20 06:00 YR - 2015 ED - 20151026 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25137430 <162. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24602934 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hu JC AU - Gandaglia G AU - Karakiewicz PI AU - Nguyen PL AU - Trinh QD AU - Shih YC AU - Abdollah F AU - Chamie K AU - Wright JL AU - Ganz PA AU - Sun M FA - Hu, Jim C FA - Gandaglia, Giorgio FA - Karakiewicz, Pierre I FA - Nguyen, Paul L FA - Trinh, Quoc-Dien FA - Shih, Ya-Chen Tina FA - Abdollah, Firas FA - Chamie, Karim FA - Wright, Jonathan L FA - Ganz, Patricia A FA - Sun, Maxine IN - Hu, Jim C. Department of Urology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. Electronic address: jchu@mednet.ucla.edu. IN - Gandaglia, Giorgio. Cancer Prognostics Health Outcomes Unit, University of Montreal Health Centre, Montreal, Quebec, Canada; Department of Urology, Universita Vita-Salute San Raffaele, Milan, Italy. IN - Karakiewicz, Pierre I. Cancer Prognostics Health Outcomes Unit, University of Montreal Health Centre, Montreal, Quebec, Canada; Department of Urology, University of Montreal Health Center, Montreal, Quebec, Canada. IN - Nguyen, Paul L. Department of Radiation Oncology, Brigham and Women's Hospital, Boston, MA, USA. IN - Trinh, Quoc-Dien. Center for Surgery and Public Health, Division of Urologic Surgery, Brigham and Women's Hospital, Boston, MA, USA. IN - Shih, Ya-Chen Tina. Section of Hospital Medicine, Department of Medicine Program in the Economics of Cancer, University of Chicago, Chicago, IL, USA. IN - Abdollah, Firas. Cancer Prognostics Health Outcomes Unit, University of Montreal Health Centre, Montreal, Quebec, Canada; Department of Urology, University of Montreal Health Center, Montreal, Quebec, Canada. IN - Chamie, Karim. Department of Urology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. IN - Wright, Jonathan L. Department of Urology, University of Washington School of Medicine, and Fred Hutchinson Cancer Research Center, Seattle, WA, USA. IN - Ganz, Patricia A. Cancer Prevention and Control Research at the Jonsson Comprehensive Cancer Center, Fielding School of Public Health, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. IN - Sun, Maxine. Cancer Prognostics Health Outcomes Unit, University of Montreal Health Centre, Montreal, Quebec, Canada. TI - Comparative effectiveness of robot-assisted versus open radical prostatectomy cancer control. CM - Comment in: Eur Urol. 2015 Mar;67(3):589; PMID: 25760412 CM - Comment in: Eur Urol. 2014 Oct;66(4):673-5; discussion 675-6; PMID: 24674148 CM - Comment in: Eur Urol. 2014 Nov;66(5):e85; PMID: 24867149 CM - Comment in: Eur Urol. 2014 Nov;66(5):e86; PMID: 24882671 SO - European Urology. 66(4):666-72, 2014 Oct AS - Eur Urol. 66(4):666-72, 2014 Oct NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Aged MH - Cohort Studies MH - Confidence Intervals MH - Follow-Up Studies MH - Humans MH - Linear Models MH - Male MH - Middle Aged MH - Neoplasm Invasiveness/pa [Pathology] MH - Neoplasm Recurrence, Local/ep [Epidemiology] MH - *Neoplasm Recurrence, Local/pa [Pathology] MH - Neoplasm Staging MH - Odds Ratio MH - Patient Safety MH - *Prostate-Specific Antigen/bl [Blood] MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/bl [Blood] MH - *Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Retrospective Studies MH - Risk Assessment MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures/mt [Methods] MH - Treatment Outcome KW - Cancer control; Positive margins; Radical prostatectomy; Robotic-assisted surgery AB - BACKGROUND: Robot-assisted radical prostatectomy (RARP) remains controversial, and no improvement in cancer control outcomes has been demonstrated over open radical prostatectomy (ORP). AB - OBJECTIVE: To examine population-based, comparative effectiveness of RARP versus ORP pertaining surgical margin status and use of additional cancer therapy. AB - DESIGN, SETTING, AND PARTICIPANTS: This was a retrospective observational study of 5556 RARP and 7878 ORP cases from 2004 to 2009 from Surveillance Epidemiology and End Results-Medicare linked data. AB - INTERVENTION: RARP versus ORP. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Propensity-based analyses were performed to minimize treatment selection biases. Generalized linear regression models were computed for comparison of RP surgical margin status and use of additional cancer therapy (radiation therapy [RT] or androgen deprivation therapy [ADT]) by surgical approach. AB - RESULTS AND LIMITATIONS: In the propensity-adjusted analysis, RARP was associated with fewer positive surgical margins (13.6% vs 18.3%; odds ratio [OR]: 0.70; 95% confidence interval [CI], 0.66-0.75), largely because of fewer RARP positive margins for intermediate-risk (15.0% vs 21.0%; OR: 0.66; 95% CI, 0.59-0.75) and high-risk (15.1% vs 20.6%; OR: 0.70; 95% CI, 0.63-0.77) disease. In addition, RARP was associated with less use of additional cancer therapy within 6 mo (4.5% vs 6.2%; OR: 0.75; 95% CI, 0.69-0.81), 12 mo (OR: 0.73; 95% CI, 0.62-0.86), and 24 mo (OR: 0.67; 95% CI, 0.57-0.78) of surgery. Limitations include the retrospective nature of the study and the absence of prostate-specific antigen levels to determine biochemical recurrence. AB - CONCLUSIONS: RARP is associated with improved surgical margin status relative to ORP for intermediate- and high-risk disease and less use of postprostatectomy ADT and RT. This has important implications for quality of life, health care delivery, and costs. AB - PATIENT SUMMARY: Robot-assisted radical prostatectomy (RP) versus open RP is associated with fewer positive margins and better early cancer control because of less use of additional androgen deprivation and radiation therapy within 2 yr of surgery. AB - Copyright © 2014 European Association of Urology. Published by Elsevier B.V. All rights reserved. RN - EC 3-4-21-77 (Prostate-Specific Antigen) ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(14)00134-1 DO - https://dx.doi.org/10.1016/j.eururo.2014.02.015 PT - Comparative Study PT - Journal Article PT - Observational Study ID - 24602934 [pubmed] ID - S0302-2838(14)00134-1 [pii] ID - 10.1016/j.eururo.2014.02.015 [doi] PP - ppublish PH - 2013/12/24 [received] PH - 2014/02/10 [accepted] LG - English EP - 20140219 DP - 2014 Oct DC - 20140915 EZ - 2014/03/08 06:00 DA - 2015/10/20 06:00 DT - 2014/03/08 06:00 YR - 2014 ED - 20151019 RD - 20151026 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24602934 <163. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25560809 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Stolzenburg JU AU - Graefen M AU - Kriegel C AU - Michl U AU - Martin Morales A AU - Pommerville PJ AU - Manning M AU - Buttner H AU - Henneges C AU - Schostak M FA - Stolzenburg, Jens-Uwe FA - Graefen, Markus FA - Kriegel, Christian FA - Michl, Uwe FA - Martin Morales, Antonio FA - Pommerville, Peter J FA - Manning, Martina FA - Buttner, Hartwig FA - Henneges, Carsten FA - Schostak, Martin IN - Stolzenburg, Jens-Uwe. Department of Urology, University Hospital Leipzig, Leipzig, Germany. IN - Graefen, Markus. Martini Hospital, UKE GmbH, Hamburg, Germany. IN - Kriegel, Christian. Department of Urology, University Hospital Leipzig, Leipzig, Germany. IN - Michl, Uwe. Martini Hospital, UKE GmbH, Hamburg, Germany. IN - Martin Morales, Antonio. Malaga Institute of Urology, Malaga, Spain. IN - Pommerville, Peter J. Department of Urological Sciences, University of British Columbia, Victoria, BC, Canada. IN - Manning, Martina. Lilly Deutschland GmbH, Bad Homburg, Germany. IN - Buttner, Hartwig. Lilly Deutschland GmbH, Bad Homburg, Germany. IN - Henneges, Carsten. Lilly Deutschland GmbH, Bad Homburg, Germany. IN - Schostak, Martin. Department of Urology and Paediatric Urology, Magdeburg University Medical Centre, Magdeburg, Germany. TI - Effect of surgical approach on erectile function recovery following bilateral nerve-sparing radical prostatectomy: an evaluation utilising data from a randomised, double-blind, double-dummy multicentre trial of tadalafil vs placebo. SO - BJU International. 116(2):241-51, 2015 Aug AS - BJU Int. 116(2):241-51, 2015 Aug NJ - BJU international PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - dcu, 100886721 IO - BJU Int. SB - Index Medicus CP - England MH - Carbolines/pd [Pharmacology] MH - *Carbolines/tu [Therapeutic Use] MH - Erectile Dysfunction/dt [Drug Therapy] MH - Erectile Dysfunction/ep [Epidemiology] MH - Humans MH - Male MH - Middle Aged MH - *Prostatectomy/ae [Adverse Effects] MH - Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/su [Surgery] MH - Recovery of Function/de [Drug Effects] MH - Tadalafil MH - Urological Agents/pd [Pharmacology] MH - *Urological Agents/tu [Therapeutic Use] KW - erectile dysfunction; nerve-sparing radical prostatectomy; prostate cancer; randomised clinical trial; surgical approach; tadalafil AB - OBJECTIVES: To report pre-specified and exploratory results on the effect of different surgical approaches on erectile function (EF) after nerve-sparing radical prostatectomy (nsRP) obtained from the multicentre, randomised, double-blind, double-dummy REACTT trial of tadalafil (once a day [OaD] or on-demand [pro-re-nata, PRN]) vs placebo. AB - PATIENTS AND METHODS: Patients aged <68 years with normal preoperative EF who underwent nsRP for localised prostate cancer (Gleason <7, prostate-specific antigen [PSA] <10 ng/mL) were randomised after nsRP 1:1:1 to 9-month double-blind treatment with tadalafil 5 mg OaD, tadalafil 20 mg PRN, or placebo, followed by 6-week drug-free washout, and 3-month open-label OaD treatment (all patients). Recovery of EF was defined as an International Index of Erectile Function (IIEF)-EF domain score of >22 and normal orgasmic function was defined based on IIEF Question 10. Both parameters were analysed at the end of washout using logistic regression including terms for treatment, country, visit, visit-by-treatment interaction, age group, nerve-sparing score (perfect = 2, non-perfect >2), and surgical approach (open surgery, robot-assisted laparoscopy, conventional laparoscopy, other). Time to EF recovery was analysed post hoc with a Cox proportional-hazards model including terms for treatment, age-group, country, surgical approach and surgery-by-treatment interaction. AB - RESULTS: Of 422 patients treated, 189 underwent open surgery, 115 robot-assisted laparoscopy, 88 conventional laparoscopy and 30 surgery classified as 'other'. The odds of achieving EF recovery at the end of drug-free washout were about twice as high for the robot-assisted laparoscopy group compared with the open surgery group (odds ratio 2.42; 95% confidence interval [CI] 1.24, 4.72; P = 0.029). Patients who underwent robot-assisted laparoscopy were significantly more likely to recover during double-blind treatment compared with patients who underwent open surgery (hazard ratio 1.92; 95% CI 1.17, 3.15; P = 0.010). No favourable effect of conventional laparoscopy compared with open surgery could be seen. AB - CONCLUSION: These results may provide further insights into the role of surgery on EF recovery after nsRP. However, the trial was not designed for these analyses and further prospective studies are needed. AB - Copyright © 2015 The Authors BJU International © 2015 BJU International Published by John Wiley & Sons Ltd. RN - 0 (Carbolines) RN - 0 (Urological Agents) RN - 742SXX0ICT (Tadalafil) ES - 1464-410X IL - 1464-4096 DO - https://dx.doi.org/10.1111/bju.13030 PT - Clinical Trial, Phase IV PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial ID - 25560809 [pubmed] ID - 10.1111/bju.13030 [doi] PP - ppublish LG - English EP - 20150420 DP - 2015 Aug DC - 20150723 EZ - 2015/01/07 06:00 DA - 2015/10/17 06:00 DT - 2015/01/07 06:00 YR - 2015 ED - 20151016 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25560809 <164. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25611898 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Eklind S AU - Lindfors A AU - Sjoli P AU - Dahm-Kahler P FA - Eklind, Saskia FA - Lindfors, Anna FA - Sjoli, Per FA - Dahm-Kahler, Pernilla IN - Eklind, Saskia. *Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Sahlgrenska Academy, Gothenburg; and +Regional Cancer Center West, Gothenburg, Sweden. TI - A prospective, comparative study on robotic versus open-surgery hysterectomy and pelvic lymphadenectomy for endometrial carcinoma. SO - International Journal of Gynecological Cancer. 25(2):250-6, 2015 Feb AS - Int J Gynecol Cancer. 25(2):250-6, 2015 Feb NJ - International journal of gynecological cancer : official journal of the International Gynecological Cancer Society PI - Journal available in: Print PI - Citation processed from: Internet JC - dzp, 9111626 IO - Int. J. Gynecol. Cancer SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - Endometrial Neoplasms/ec [Economics] MH - Endometrial Neoplasms/ep [Epidemiology] MH - *Endometrial Neoplasms/su [Surgery] MH - Female MH - Humans MH - Hysterectomy/ec [Economics] MH - Hysterectomy/is [Instrumentation] MH - *Hysterectomy/mt [Methods] MH - Laparoscopy/ec [Economics] MH - Laparoscopy/mt [Methods] MH - Laparotomy/ec [Economics] MH - Laparotomy/mt [Methods] MH - Length of Stay/ec [Economics] MH - Length of Stay/sn [Statistics & Numerical Data] MH - Lymph Node Excision/ec [Economics] MH - Lymph Node Excision/is [Instrumentation] MH - *Lymph Node Excision/mt [Methods] MH - Lymphatic Metastasis MH - Middle Aged MH - Patient Satisfaction/ec [Economics] MH - Patient Satisfaction/sn [Statistics & Numerical Data] MH - Pelvis MH - Postoperative Complications/ec [Economics] MH - Postoperative Complications/ep [Epidemiology] MH - Robotic Surgical Procedures/ec [Economics] MH - *Robotic Surgical Procedures AB - OBJECTIVES: The aim of this study was to compare surgical outcome, patient recovery, and costs between robot-assisted laparoscopy and laparotomy in women undergoing hysterectomy, bilateral salpingo-oophorectomy (BSOE), and pelvic lymphadenectomy for endometrial carcinoma. AB - METHODS: Women undergoing hysterectomy, BSOE, and pelvic lymphadenectomy for endometrial carcinoma, according to regional guidelines, were prospectively, concurrently, and consecutively included from September 2010 to December 2012. Surgical outcomes such as operative time, estimated blood loss (EBL), number of lymph nodes retrieved, and complications were analyzed together with hospital stay, days until normal active daily living was retrieved, patient satisfaction with the length of the hospital stay, and cost per patient. Robot-assisted laparoscopy was performed on all cases at the Sahlgrenska University Hospital, and laparotomy was performed on all cases at 3 regional hospitals. AB - RESULTS: Forty women underwent robot-assisted laparoscopy, and 48 underwent laparotomy. There were no differences in age, body mass index, histology, or retrieved lymph nodes. Operative time was significantly shorter in the robot-assisted laparoscopy group (P < 0.0001). The EBL was lower and hospital stay was shorter in the robot-assisted laparoscopy group (P < 0.0001). There was no statistical difference in complications between the groups, and both groups found hospital stay duration satisfactory. In the robot-assisted laparoscopy group, active daily living was normal within 5 days postoperatively, compared with 14 days in the laparotomy group (P < 0.0001). Calculated costs per treated patient did not differ statistically between the groups. AB - CONCLUSIONS: Compared with laparotomy and robot-assisted laparoscopic hysterectomy, BSOE pelvic lymphadenectomy for endometrial carcinoma was associated with significantly shorter operative time, hospital stay, and lower EBL. Patients recovered more quickly after robot-assisted laparoscopy, with equal costs number of retrieved lymph nodes, compared with laparotomy. ES - 1525-1438 IL - 1048-891X DI - 00009577-201502000-00011 DO - https://dx.doi.org/10.1097/IGC.0000000000000357 PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article PT - Multicenter Study PT - Research Support, Non-U.S. Gov't ID - 25611898 [pubmed] ID - 10.1097/IGC.0000000000000357 [doi] ID - 00009577-201502000-00011 [pii] PP - ppublish LG - English DP - 2015 Feb DC - 20150123 EZ - 2015/01/23 06:00 DA - 2015/10/16 06:00 DT - 2015/01/23 06:00 YR - 2015 ED - 20151014 RD - 20150123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25611898 <165. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25891205 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Chiffer RC AU - Schwab RJ AU - Keenan BT AU - Borek RC AU - Thaler ER FA - Chiffer, Rebecca C FA - Schwab, Richard J FA - Keenan, Brendan T FA - Borek, Ryan C FA - Thaler, Erica R IN - Chiffer, Rebecca C. Department of Otorhinolaryngology-Head and Neck Surgery, Hospital of the University of Pennsylvania, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, U.S.A. IN - Schwab, Richard J. Department of Medicine, Division of Sleep Medicine, Pulmonary, Allergy and Critical Care Division, Penn Sleep Center, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, U.S.A. IN - Keenan, Brendan T. Perelman School of Medicine at the University of Pennsylvania, Division of Sleep Medicine, Center for Sleep and Circadian Neurobiology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, U.S.A. IN - Borek, Ryan C. Department of Otorhinolaryngology-Head and Neck Surgery, Hospital of the University of Pennsylvania, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, U.S.A. IN - Thaler, Erica R. Department of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine at the University of Pennsylvania, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, U.S.A. TI - Volumetric MRI analysis pre- and post-Transoral robotic surgery for obstructive sleep apnea. SO - Laryngoscope. 125(8):1988-95, 2015 Aug AS - Laryngoscope. 125(8):1988-95, 2015 Aug NJ - The Laryngoscope PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 8607378, l1w IO - Laryngoscope SB - Index Medicus CP - United States MH - Adult MH - Female MH - Humans MH - *Magnetic Resonance Imaging/mt [Methods] MH - Male MH - Middle Aged MH - Mouth MH - *Natural Orifice Endoscopic Surgery/mt [Methods] MH - Palate, Soft/pa [Pathology] MH - *Palate, Soft/su [Surgery] MH - Polysomnography MH - Postoperative Period MH - Preoperative Period MH - Prospective Studies MH - *Robotics/mt [Methods] MH - Sleep Apnea, Obstructive/di [Diagnosis] MH - *Sleep Apnea, Obstructive/su [Surgery] MH - Treatment Outcome MH - Young Adult KW - Transoral robotic surgery; obstructive sleep apnea; uvulopalatopharyngoplasty; volumetric MRI analysis AB - OBJECTIVES/HYPOTHESIS: To quantitatively measure volumetric changes in upper airway soft tissue structures using magnetic resonance imaging (MRI) pre- and post transoral robotic surgery for obstructive sleep apnea (OSA-TORS). AB - STUDY DESIGN: Prospective, nonrandomized, institutional board-approved study. AB - METHODS: Apneics undergoing OSA-TORS, which included bilateral posterior hemiglossectomy with limited pharyngectomy and uvulopalatopharyngoplasty, had upper airway MRIs pre- and postoperatively. Changes (percent and absolute values) in upper airway and surrounding soft tissue volumes were calculated. We assessed whether there were significant volumetric changes and if changes correlated with apnea-hypopnea index (AHI) changes. AB - RESULTS: Nineteen MRIs and 18 polysomnograms were analyzed pre- and postoperation. Total airway volume increased by 19.4% (P=0.030). Soft palate and tongue volumes decreased by 18.3% (P=0.002) and 5.8% (P=0.013), respectively. Retropalatal and total lateral wall volumes decreased by 49.8% (P=0.0001) and 17.9% (P=0.008), respectively. Changes in other structures were not significant. Eleven patients had surgical success, with a mean AHI decrease of 52.9; six were nonsuccesses with a mean AHI decrease of 4.5 (P =0.006). Decreased retropalatal lateral wall volume correlated with decreased AHI. AB - CONCLUSION: Airway, tongue, soft palate, and lateral wall volumes change significantly after OSA-TORS. Changes in the volume of the lateral walls correlated with changes in AHI. Volumetric upper airway MRI may be a helpful tool to better understand reasons for surgical success. AB - LEVEL OF EVIDENCE: 4. AB - Copyright © 2015 The American Laryngological, Rhinological and Otological Society, Inc. ES - 1531-4995 IL - 0023-852X DO - https://dx.doi.org/10.1002/lary.25270 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 25891205 [pubmed] ID - 10.1002/lary.25270 [doi] PP - ppublish PH - 2014/09/07 [received] PH - 2015/01/27 [revised] PH - 2015/02/25 [accepted] LG - English EP - 20150417 DP - 2015 Aug DC - 20150723 EZ - 2015/04/21 06:00 DA - 2015/10/07 06:00 DT - 2015/04/22 06:00 YR - 2015 ED - 20151006 RD - 20150723 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25891205 <166. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25315960 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Jeong CW AU - Lee JK AU - Oh JJ AU - Lee S AU - Jeong SJ AU - Hong SK AU - Byun SS AU - Lee SE FA - Jeong, Chang Wook FA - Lee, Jung Keun FA - Oh, Jong Jin FA - Lee, Sangchul FA - Jeong, Seong Jin FA - Hong, Sung Kyu FA - Byun, Seok-Soo FA - Lee, Sang Eun IN - Jeong, Chang Wook. Department of Urology, Seoul National University Hospital, Seoul, Republic of Korea; Department of Urology, College of Medicine, Seoul National University, Seoul, Republic of Korea. IN - Lee, Jung Keun. Department of Urology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea. IN - Oh, Jong Jin. Department of Urology, College of Medicine, Seoul National University, Seoul, Republic of Korea; Department of Urology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea. IN - Lee, Sangchul. Department of Urology, College of Medicine, Seoul National University, Seoul, Republic of Korea; Department of Urology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea. IN - Jeong, Seong Jin. Department of Urology, College of Medicine, Seoul National University, Seoul, Republic of Korea; Department of Urology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea. IN - Hong, Sung Kyu. Department of Urology, College of Medicine, Seoul National University, Seoul, Republic of Korea; Department of Urology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea. IN - Byun, Seok-Soo. Department of Urology, College of Medicine, Seoul National University, Seoul, Republic of Korea; Department of Urology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea. IN - Lee, Sang Eun. Department of Urology, College of Medicine, Seoul National University, Seoul, Republic of Korea; Department of Urology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea. Electronic address: selee@snubh.org. TI - Effects of new 1-step posterior reconstruction method on recovery of continence after robot-assisted laparoscopic prostatectomy: results of a prospective, single-blind, parallel group, randomized, controlled trial. SO - Journal of Urology. 193(3):935-42, 2015 Mar AS - J Urol. 193(3):935-42, 2015 Mar NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Humans MH - *Laparoscopy MH - Male MH - Prospective Studies MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - Recovery of Function MH - *Robotic Surgical Procedures MH - Single-Blind Method MH - Urinary Incontinence/et [Etiology] MH - *Urinary Incontinence/pc [Prevention & Control] KW - prostatectomy; prostatic neoplasms; robotics; treatment outcome; urinary incontinence AB - PURPOSE: We devised a 1-step posterior reconstruction technique that opposes the median dorsal raphe only to the posterior counterpart of the detrusor apron rather than to Denonvilliers' fascia. In a retrospective study we previously found that during robot-assisted laparoscopic prostatectomy this new technique could significantly shorten continence recovery time. We designed a prospective clinical trial to confirm this. AB - MATERIALS AND METHODS: We designed a single-blind, parallel group, randomized, controlled trial. A total of 100 men who underwent robot-assisted laparoscopic prostatectomy performed by a single surgeon at a referral center were randomly allocated to the intervention group (50) or the control group (50) from October 2012 through August 2013. The intervention group underwent posterior reconstruction with this new technique before vesicourethral anastomosis. All patients in each group were treated with anterior reconstruction. The study primary end point was time to continence recovery, defined as no pad use. Secondary outcomes were time to recovery of social continence, defined as 0 or 1 pad used per day. AB - RESULTS: One control was excluded from analysis due to open conversion and 4 patients were excluded since they withdrew from participation. Median time to complete continence recovery did not differ significantly between the intervention and control groups (106 and 119 days, respectively, p = 0.890). However, time to social continence recovery was significantly shorter in the intervention group than in controls (median 18 vs 30 days, p = 0.024). AB - CONCLUSIONS: One-step posterior reconstruction did not significantly shorten time to complete continence recovery. However, it seemed to have a marginal benefit on early recovery of social continence. AB - Copyright © 2015 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(14)04641-2 DO - https://dx.doi.org/10.1016/j.juro.2014.10.023 PT - Journal Article PT - Randomized Controlled Trial ID - 25315960 [pubmed] ID - S0022-5347(14)04641-2 [pii] ID - 10.1016/j.juro.2014.10.023 [doi] PP - ppublish PH - 2014/10/06 [accepted] LG - English EP - 20141012 DP - 2015 Mar DC - 20150313 EZ - 2014/10/16 06:00 DA - 2015/10/01 06:00 DT - 2014/10/16 06:00 YR - 2015 ED - 20150930 RD - 20150313 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25315960 <167. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26002986 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Corrado G AU - Cutillo G AU - Pomati G AU - Mancini E AU - Sperduti I AU - Patrizi L AU - Saltari M AU - Vincenzoni C AU - Baiocco E AU - Vizza E FA - Corrado, G FA - Cutillo, G FA - Pomati, G FA - Mancini, E FA - Sperduti, I FA - Patrizi, L FA - Saltari, M FA - Vincenzoni, C FA - Baiocco, E FA - Vizza, E IN - Corrado, G. Gynecologic Oncology Unit, "Regina Elena" National Cancer Institute, Rome, Italy. Electronic address: giacomo.corrado@alice.it. IN - Cutillo, G. Gynecologic Oncology Unit, "Regina Elena" National Cancer Institute, Rome, Italy. IN - Pomati, G. Department of Surgery, Section of Gynaecology and Obstetrics, Tor Vergata University, Rome, Italy. IN - Mancini, E. Gynecologic Oncology Unit, "Regina Elena" National Cancer Institute, Rome, Italy. IN - Sperduti, I. Scientific Direction, "Regina Elena" National Cancer Institute, Rome, Italy. IN - Patrizi, L. Department of Surgery, Section of Gynaecology and Obstetrics, Tor Vergata University, Rome, Italy. IN - Saltari, M. Department of Surgery, Section of Gynaecology and Obstetrics, Tor Vergata University, Rome, Italy. IN - Vincenzoni, C. Gynecologic Oncology Unit, "Regina Elena" National Cancer Institute, Rome, Italy. IN - Baiocco, E. Gynecologic Oncology Unit, "Regina Elena" National Cancer Institute, Rome, Italy. IN - Vizza, E. Gynecologic Oncology Unit, "Regina Elena" National Cancer Institute, Rome, Italy. TI - Surgical and oncological outcome of robotic surgery compared to laparoscopic and abdominal surgery in the management of endometrial cancer. SO - European Journal of Surgical Oncology. 41(8):1074-81, 2015 Aug AS - Eur J Surg Oncol. 41(8):1074-81, 2015 Aug NJ - European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 8504356, eur IO - Eur J Surg Oncol SB - Index Medicus CP - England MH - Adult MH - Aged MH - Aged, 80 and over MH - Endometrial Neoplasms/di [Diagnosis] MH - Endometrial Neoplasms/mo [Mortality] MH - *Endometrial Neoplasms/su [Surgery] MH - Female MH - Follow-Up Studies MH - Humans MH - *Hysterectomy/mt [Methods] MH - Incidence MH - Italy/ep [Epidemiology] MH - *Laparoscopy/mt [Methods] MH - *Laparotomy/mt [Methods] MH - Middle Aged MH - Neoplasm Recurrence, Local/ep [Epidemiology] MH - *Neoplasm Staging MH - *Postoperative Complications/ep [Epidemiology] MH - Retrospective Studies MH - *Robotics/mt [Methods] MH - Survival Rate/td [Trends] MH - Treatment Outcome KW - Abdominal hysterectomy; Endometrial cancer; Laparoscopic hysterectomy; Minimally invasive surgery; Robotic hysterectomy AB - OBJECTIVE: To compare different techniques of minimally invasive surgery (laparoscopy and robotics) to abdominal surgery in order to identify the optimal surgical technique in the treatment of endometrial cancer. AB - METHODS AND MATERIALS: A single-institutional, matched, retrospective, cohort study was performed. All patients with clinical stage I or occult stage II endometrial cancer who underwent robotic hysterectomy, bilateral salpingo-oophorectomy +/- lymphadenectomy from August 2010 and December 2013 were identified. Surgical and oncological outcomes were compared with patients matched by age, body mass index, tumor histology, and grade, who underwent abdominal or laparoscopic surgery between January 2001 and December 2013. AB - RESULTS: Three groups were identified: 177 laparotomies (group A), 277 laparoscopies (group B) and 72 robotics (group C). There were no statistically significant differences between the three groups in terms of age, BMI and FIGO stage. The operative time was shortest in group B (p = 0.0001). Blood loss and transfusions were equivalent in group B and C, while they were greater in group A (p = 0.0001). The intra-operative, early and late postoperative complications, rate of conversion, the re-intervention and median hospital stay were lower in group C. The rate of recurrence and death from disease was similar in all three groups. AB - CONCLUSIONS: Minimally invasive surgery was superior to abdominal surgery in terms of surgical outcomes. Robotic surgery was superior to laparoscopy in terms of intra- and post-operative complications, conversion rates, length of hospital stay and re-interventions. In terms of oncological outcomes the three groups were equivalent. AB - Copyright © 2015 Elsevier Ltd. All rights reserved. ES - 1532-2157 IL - 0748-7983 DI - S0748-7983(15)00428-X DO - https://dx.doi.org/10.1016/j.ejso.2015.04.020 PT - Journal Article PT - Randomized Controlled Trial ID - 26002986 [pubmed] ID - S0748-7983(15)00428-X [pii] ID - 10.1016/j.ejso.2015.04.020 [doi] PP - ppublish PH - 2015/03/19 [received] PH - 2015/04/22 [revised] PH - 2015/04/30 [accepted] LG - English EP - 20150509 DP - 2015 Aug DC - 20150710 EZ - 2015/05/25 06:00 DA - 2015/09/22 06:00 DT - 2015/05/25 06:00 YR - 2015 ED - 20150921 RD - 20150710 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26002986 <168. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26099895 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lebeis C AU - Canes D AU - Sorcini A AU - Moinzadeh A FA - Lebeis, Christopher FA - Canes, David FA - Sorcini, Andrea FA - Moinzadeh, Alireza IN - Lebeis, Christopher. Institute of Urology, Lahey Hospital and Medical Center, Burlington, MA. IN - Canes, David. Institute of Urology, Lahey Hospital and Medical Center, Burlington, MA. IN - Sorcini, Andrea. Institute of Urology, Lahey Hospital and Medical Center, Burlington, MA. IN - Moinzadeh, Alireza. Institute of Urology, Lahey Hospital and Medical Center, Burlington, MA. Electronic address: Alireza.Moinzadeh@Lahey.org. TI - Novel Technique Prevents Lymphoceles After Transperitoneal Robotic-assisted Pelvic Lymph Node Dissection: Peritoneal Flap Interposition. SO - Urology. 85(6):1505-9, 2015 Jun AS - Urology. 85(6):1505-9, 2015 Jun NJ - Urology PI - Journal available in: Print PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Humans MH - Lymph Node Excision/ae [Adverse Effects] MH - *Lymph Node Excision/mt [Methods] MH - Lymphocele/et [Etiology] MH - *Lymphocele/pc [Prevention & Control] MH - Male MH - Middle Aged MH - Pelvis MH - *Peritoneum/tr [Transplantation] MH - Prospective Studies MH - *Prostatectomy MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotic Surgical Procedures MH - *Surgical Flaps AB - INTRODUCTION: To determine the efficacy of our novel technique to prevent lymphocele formation after pelvic lymph node dissection (PLND) after robotic-assisted radical prostatectomy (RARP) using the existing peritoneum of the bladder. AB - TECHNICAL CONSIDERATIONS: We evaluated 155 consecutive patients undergoing RARP with PLND over 24 months. Group A included the first 77 patients with PLND using standard technique (no peritoneal flap). Group B included the subsequent 78 patients (1 patient excluded) with PLND and peritoneal interposition flap. The peritoneal interposition flap is created by rotating and advancing the peritoneum around the lateral surface of the ipsilateral bladder to the dependent portion of the pelvis and fixing it to the bladder itself. A cystogram was performed in 91% of the patients 7-14 days after the surgery. Lymphocele formation rates were compared (based on symptoms, cystogram findings, and radiographic confirmation). AB - RESULTS: The 2 groups were statistically equivalent in terms of prostate-specific antigen, age, blood loss, body mass index, Gleason score, prostate size, pathology, or heparin use. Lymphocele formation occurred in 9 of 77 (11.6%) group A patients and in 0 of 77 group B patients (P = .003). Mean time to lymphocele detection in group A was 30.4 days. Mean follow-up in groups A and B were 383.97 and 379 days, respectively (P = .91). AB - CONCLUSION: Strategic rotation and fixation of a peritoneal flap around the lateral aspect of the bladder during transperitoneal RARP with PLND is a novel technique to prevent lymphocele formation. Given the sample size and single institutional study, a prospective, randomized, multi-institutional trial is planned. AB - Copyright © 2015 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(15)00212-5 DO - https://dx.doi.org/10.1016/j.urology.2015.02.034 PT - Clinical Trial PT - Journal Article ID - 26099895 [pubmed] ID - S0090-4295(15)00212-5 [pii] ID - 10.1016/j.urology.2015.02.034 [doi] PP - ppublish PH - 2014/09/05 [received] PH - 2015/02/22 [revised] PH - 2015/02/27 [accepted] LG - English DP - 2015 Jun DC - 20150623 EZ - 2015/06/24 06:00 DA - 2015/09/09 06:00 DT - 2015/06/24 06:00 YR - 2015 ED - 20150908 RD - 20150623 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26099895 <169. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25543068 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Whitehurst SV AU - Lockrow EG AU - Lendvay TS AU - Propst AM AU - Dunlow SG AU - Rosemeyer CJ AU - Gobern JM AU - White LW AU - Skinner A AU - Buller JL FA - Whitehurst, Sabrina V FA - Lockrow, Ernest G FA - Lendvay, Thomas S FA - Propst, Anthony M FA - Dunlow, Susan G FA - Rosemeyer, Christopher J FA - Gobern, Joseph M FA - White, Lee W FA - Skinner, Anna FA - Buller, Jerome L IN - Whitehurst, Sabrina V. Department of Obstetrics and Gynecology, Walter Reed National Military Medical Center, Bethesda, Maryland. IN - Lockrow, Ernest G. Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, Maryland. Electronic address: ernest.lockrow@usuhs.edu. IN - Lendvay, Thomas S. Department of Urology, Seattle Children's Hospital, Seattle, Washington. IN - Propst, Anthony M. Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, Maryland. IN - Dunlow, Susan G. Department of Obstetrics and Gynecology, Walter Reed National Military Medical Center, Bethesda, Maryland. IN - Rosemeyer, Christopher J. Department of Obstetrics and Gynecology, Tripler Army Medical Center, Honolulu, Hawaii. IN - Gobern, Joseph M. Department of Obstetrics and Gynecology, Walter Reed National Military Medical Center, Bethesda, Maryland. IN - White, Lee W. Bioengineering Department, University of Washington, Seattle, Washington. IN - Skinner, Anna. Anthotronix, Silver Spring, Maryland. IN - Buller, Jerome L. Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, Maryland. TI - Comparison of two simulation systems to support robotic-assisted surgical training: a pilot study (Swine model). SO - Journal of Minimally Invasive Gynecology. 22(3):483-8, 2015 Mar-Apr AS - J Minim Invasive Gynecol. 22(3):483-8, 2015 Mar-Apr NJ - Journal of minimally invasive gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101235322 IO - J Minim Invasive Gynecol SB - Index Medicus CP - United States MH - Adult MH - Animals MH - Clinical Competence MH - *Computer Simulation MH - Curriculum MH - Cystotomy/mt [Methods] MH - Educational Measurement MH - Humans MH - Laparoscopy/ed [Education] MH - Laparoscopy/mt [Methods] MH - *Laparoscopy MH - Models, Animal MH - Pilot Projects MH - Program Evaluation MH - Prospective Studies MH - *Robotics MH - Swine MH - Task Performance and Analysis MH - User-Computer Interface KW - Robotic surgery; Simulation; Virtual reality; dV-Trainer; da Vinci Surgical System AB - OBJECTIVE: To compare the efficacy of simulation-based training between the Mimic dV- Trainer and traditional dry lab da Vinci robot training. AB - DESIGN: A prospective randomized study analyzing the performance of 20 robotics-naive participants. Participants were enrolled in an online da Vinci Intuitive Surgical didactic training module, followed by training in use of the da Vinci standard surgical robot. Spatial ability tests were performed as well. Participants were randomly assigned to 1 of 2 training conditions: performance of 3 Fundamentals of Laparoscopic Surgery dry lab tasks using the da Vinci or performance of 4 dV-Trainer tasks. Participants in both groups performed all tasks to empirically establish proficiency criterion. Participants then performed the transfer task, a cystotomy closure using the daVinci robot on a live animal (swine) model. The performance of robotic tasks was blindly assessed by a panel of experienced surgeons using objective tracking data and using the validated Global Evaluative Assessment of Robotic Surgery (GEARS), a structured assessment tool. AB - RESULTS: No statistically significant difference in surgeon performance was found between the 2 training conditions, dV-Trainer and da Vinci robot. Analysis of a 95% confidence interval for the difference in means (-0.803 to 0.543) indicated that the 2 methods are unlikely to differ to an extent that would be clinically meaningful. AB - CONCLUSION: Based on the results of this study, a curriculum on the dV- Trainer was shown to be comparable to traditional da Vinci robot training. Therefore, we have identified that training on a virtual reality system may be an alternative to live animal training for future robotic surgeons. AB - Copyright Published by Elsevier Inc. ES - 1553-4669 IL - 1553-4650 DI - S1553-4650(14)01765-8 DO - https://dx.doi.org/10.1016/j.jmig.2014.12.160 PT - Journal Article PT - Randomized Controlled Trial ID - 25543068 [pubmed] ID - S1553-4650(14)01765-8 [pii] ID - 10.1016/j.jmig.2014.12.160 [doi] PP - ppublish PH - 2014/11/04 [received] PH - 2014/12/11 [revised] PH - 2014/12/16 [accepted] LG - English EP - 20141224 DP - 2015 Mar-Apr DC - 20150306 EZ - 2014/12/28 06:00 DA - 2015/09/01 06:00 DT - 2014/12/30 06:00 YR - 2015 ED - 20150828 RD - 20150306 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25543068 <170. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24609641 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - van Loon JW AU - Smeele LE AU - Hilgers FJ AU - van den Brekel MW FA - van Loon, J W L FA - Smeele, L E FA - Hilgers, F J M FA - van den Brekel, M W M IN - van Loon, J W L. Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. TI - Outcome of transoral robotic surgery for stage I-II oropharyngeal cancer. SO - European Archives of Oto-Rhino-Laryngology. 272(1):175-83, 2015 Jan AS - Eur Arch Otorhinolaryngol. 272(1):175-83, 2015 Jan NJ - European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - anb, 9002937 IO - Eur Arch Otorhinolaryngol SB - Index Medicus CP - Germany MH - Aged MH - Carcinoma, Squamous Cell/pa [Pathology] MH - *Carcinoma, Squamous Cell/su [Surgery] MH - Feasibility Studies MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Mouth MH - *Natural Orifice Endoscopic Surgery/mt [Methods] MH - *Neoplasm Staging MH - Oropharyngeal Neoplasms/pa [Pathology] MH - *Oropharyngeal Neoplasms/su [Surgery] MH - Prospective Studies MH - *Robotics/mt [Methods] MH - Time Factors MH - Treatment Outcome AB - Traditionally T1-2N0 oropharyngeal carcinoma is treated with a single treatment modality, being either radiotherapy or surgery. Currently, minimally invasive surgery, such as transoral robotic surgery (TORS), is gaining popularity. The aim of this study is to assess whether T1-2N0 oropharyngeal cancer can be safely and effectively resected with TORS, and to determine the oncologic and functional outcomes. In addition, the long-term quality-of-life outcomes are reported. Between 2007 and 2012, 18 patients with early stage oropharyngeal cancers underwent transoral resection with the da Vinci robot system in the Netherlands Cancer Institute. All surviving patients filled out the self-report assessments of quality-of-life questionnaires. Median robot-assisted operating time was 115 min (range 43-186 min), while median estimated blood loss was 5 ml (range 0-125 ml). In three cases the exposure was insufficient to obtain clear tumor margins because of tumor extension and local anatomy. Fourteen patients had clear surgical margins. Four patients received adjuvant radiotherapy. Nine patients underwent an elective unilateral neck dissection. The oropharyngeal cancer recurred in two patients. Regarding the quality of life, patients who needed postoperative radiotherapy had a worse outcome and patients treated with transoral resection only did quite well. TORS seems to be an oncologically safe surgical treatment for early stage T1-2N0 oropharyngeal cancer based on this relatively small group of patients. Selecting patients in whom sufficient surgical exposure can be obtained, should be performed with the greatest care to avoid the need for adjuvant radiotherapy. Comparing radiotherapy and TORS or CO2 laser should be the next step in finding the optimal treatment for patients with T1-2N0 oropharyngeal carcinoma. ES - 1434-4726 IL - 0937-4477 DO - https://dx.doi.org/10.1007/s00405-014-2939-0 PT - Clinical Trial PT - Journal Article ID - 24609641 [pubmed] ID - 10.1007/s00405-014-2939-0 [doi] PP - ppublish PH - 2013/08/13 [received] PH - 2014/02/06 [accepted] LG - English EP - 20140308 DP - 2015 Jan DC - 20150105 EZ - 2014/03/11 06:00 DA - 2015/08/26 06:00 DT - 2014/03/13 06:00 YR - 2015 ED - 20150825 RD - 20150105 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24609641 <171. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26039115 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kim CW AU - Baik SH AU - Roh YH AU - Kang J AU - Hur H AU - Min BS AU - Lee KY AU - Kim NK FA - Kim, Chang Woo FA - Baik, Seung Hyuk FA - Roh, Yun Ho FA - Kang, Jeonghyun FA - Hur, Hyuk FA - Min, Byung Soh FA - Lee, Kang Young FA - Kim, Nam Kyu IN - Kim, Chang Woo. Division of Colon and Rectal Surgery (CWK, SHB, JK, HH, BSM, KYL, NKK), Department of Surgery, Severance Hospital; and Biostatistics Collaboration Unit (YHR), Yonsei University College of Medicine, Seoul, South Korea. TI - Cost-effectiveness of robotic surgery for rectal cancer focusing on short-term outcomes: a propensity score-matching analysis. SO - Medicine. 94(22):e823, 2015 Jun AS - Medicine (Baltimore). 94(22):e823, 2015 Jun NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616367 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adenocarcinoma/pa [Pathology] MH - *Adenocarcinoma/su [Surgery] MH - Adenoma/pa [Pathology] MH - *Adenoma/su [Surgery] MH - Adult MH - Aged MH - Cost-Benefit Analysis MH - Female MH - Hospital Charges MH - Humans MH - *Laparoscopy/ec [Economics] MH - Male MH - Matched-Pair Analysis MH - Middle Aged MH - Operative Time MH - Propensity Score MH - *Rectal Neoplasms/su [Surgery] MH - Republic of Korea MH - *Robotic Surgical Procedures/ec [Economics] MH - Time Factors MH - Treatment Outcome AB - Although the total cost of robotic surgery (RS) is known to be higher than that of laparoscopic surgery (LS), the cost-effectiveness of RS has not yet been verified. The aim of the study is to clarify the cost-effectiveness of RS compared with LS for rectal cancer.From January 2007 through December 2011, 311 and 560 patients underwent totally RS and conventional LS for rectal cancer, respectively. A propensity score-matching analysis was performed with a ratio of 1:1 to reduce the possibility of selection bias. Costs and perioperative short-term outcomes in both the groups were compared. Additional costs due to readmission were also analyzed.The characteristics of the patients were not different between the 2 groups. Most perioperative outcomes were not different between the groups except for the operation time. Complications within 30 days of surgery were not significantly different. Total hospital charges and patients' bill were higher in RS than in LS. The total hospital charges for patients who recovered with or without complications were higher in RS than in LS, although their short-term outcomes were similar. In patients with complications, the postoperative course after RS appeared to be milder than that of LS. Total hospital charges for patients who were readmitted due to complications were similar between the groups.RS showed similar short-term outcomes with higher costs than LS. Therefore, cost-effectiveness focusing on short-term perioperative outcomes of RS was not demonstrated. ES - 1536-5964 IL - 0025-7974 DI - 00005792-201506010-00002 DO - https://dx.doi.org/10.1097/MD.0000000000000823 PT - Comparative Study PT - Journal Article PT - Observational Study ID - 26039115 [pubmed] ID - 10.1097/MD.0000000000000823 [doi] ID - 00005792-201506010-00002 [pii] ID - PMC4616367 [pmc] PP - ppublish LG - English DP - 2015 Jun DC - 20150604 EZ - 2015/06/04 06:00 DA - 2015/08/21 06:00 DT - 2015/06/04 06:00 YR - 2015 ED - 20150820 RD - 20151111 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=26039115 <172. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25582711 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Buckmire RA AU - Wong YT AU - Deal AM FA - Buckmire, Robert A FA - Wong, Yu-Tung FA - Deal, Allison M IN - Buckmire, Robert A. Department of Otolaryngology-Head & Neck Surgery, University of North Carolina Hospitals, Chapel Hill, North Carolina, U.S.A. IN - Wong, Yu-Tung. Division of Otolaryngology-Head & Neck Surgery, University of California San Diego School of Medicine, San Diego, California, U.S.A. IN - Deal, Allison M. and the Lineberger Comprehensive Cancer Center Biostatistics Core, University of North Carolina Hospitals, Chapel Hill, North Carolina, U.S.A. TI - The application of robotics to microlaryngeal laser surgery. SO - Laryngoscope. 125(6):1393-400, 2015 Jun AS - Laryngoscope. 125(6):1393-400, 2015 Jun NJ - The Laryngoscope PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 8607378, l1w IO - Laryngoscope SB - Index Medicus CP - United States MH - Adult MH - Cross-Sectional Studies MH - Equipment Design MH - Female MH - Humans MH - *Larynx/su [Surgery] MH - *Laser Therapy/mt [Methods] MH - Male MH - *Microsurgery/mt [Methods] MH - Middle Aged MH - Robotic Surgical Procedures/is [Instrumentation] MH - *Robotic Surgical Procedures KW - CO2 laser; Robotic surgery; laser guidance; learning curve; microlaryngeal surgery AB - OBJECTIVES/HYPOTHESIS: To evaluate the performance of human subjects, using a prototype robotic micromanipulator controller in a simulated, microlaryngeal operative setting. AB - STUDY DESIGN: Observational cross-sectional study. AB - METHODS: Twenty-two human subjects with varying degrees of laser experience performed CO2 laser surgical tasks within a simulated microlaryngeal operative setting using an industry standard manual micromanipulator (MMM) and a prototype robotic micromanipulator controller (RMC). Accuracy, repeatability, and ablation consistency measures were obtained for each human subject across both conditions and for the preprogrammed RMC device. AB - RESULTS: Using the standard MMM, surgeons with >10 previous laser cases performed superior to subjects with fewer cases on measures of error percentage and cumulative error (P=.045 and .03, respectively). No significant differences in performance were observed between subjects using the RMC device. In the programmed (P/A) mode, the RMC performed equivalently or superiorly to experienced human subjects on accuracy and repeatability measures, and nearly an order of magnitude better on measures of ablation consistency. The programmed RMC performed significantly better for repetition error when compared to human subjects with <100 previous laser cases (P=.04). AB - CONCLUSIONS: Experienced laser surgeons perform better than novice surgeons on tasks of accuracy and repeatability using the MMM device but roughly equivalently using the novel RMC. Operated in the P/A mode, the RMC performs equivalently or superior to experienced laser surgeons using the industry standard MMM for all measured parameters, and delivers an ablation consistency nearly an order of magnitude better than human laser operators. AB - LEVEL OF EVIDENCE: NA. AB - Copyright © 2014 The American Laryngological, Rhinological and Otological Society, Inc. ES - 1531-4995 IL - 0023-852X DO - https://dx.doi.org/10.1002/lary.25134 PT - Evaluation Studies PT - Journal Article PT - Observational Study ID - 25582711 [pubmed] ID - 10.1002/lary.25134 [doi] PP - ppublish PH - 2014/12/10 [accepted] LG - English EP - 20150113 DP - 2015 Jun DC - 20150520 EZ - 2015/01/14 06:00 DA - 2015/08/08 06:00 DT - 2015/01/15 06:00 YR - 2015 ED - 20150806 RD - 20150520 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25582711 <173. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24656756 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Buffi NM AU - Lughezzani G AU - Fossati N AU - Lazzeri M AU - Guazzoni G AU - Lista G AU - Larcher A AU - Abrate A AU - Fiori C AU - Cestari A AU - Porpiglia F FA - Buffi, Nicolo Maria FA - Lughezzani, Giovanni FA - Fossati, Nicola FA - Lazzeri, Massimo FA - Guazzoni, Giorgio FA - Lista, Giuliana FA - Larcher, Alessandro FA - Abrate, Alberto FA - Fiori, Cristian FA - Cestari, Andrea FA - Porpiglia, Francesco IN - Buffi, Nicolo Maria. Department of Urology, San Raffaele Turro Hospital, Milan, Italy. Electronic address: buffi.nicolomaria@gmail.com. IN - Lughezzani, Giovanni. Department of Urology, San Raffaele Turro Hospital, Milan, Italy. IN - Fossati, Nicola. Department of Urology, San Raffaele Turro Hospital, Milan, Italy. IN - Lazzeri, Massimo. Department of Urology, San Raffaele Turro Hospital, Milan, Italy. IN - Guazzoni, Giorgio. Department of Urology, San Raffaele Turro Hospital, Milan, Italy. IN - Lista, Giuliana. Department of Urology, San Raffaele Turro Hospital, Milan, Italy. IN - Larcher, Alessandro. Department of Urology, San Raffaele Turro Hospital, Milan, Italy. IN - Abrate, Alberto. Department of Urology, San Raffaele Turro Hospital, Milan, Italy. IN - Fiori, Cristian. Department of Urology, San Luigi Gonzaga Hospital, Orbassano, Turin, Italy. IN - Cestari, Andrea. Department of Urology, Istituto Auxologico Italiano, Milan, Italy. IN - Porpiglia, Francesco. Department of Urology, San Luigi Gonzaga Hospital, Orbassano, Turin, Italy. TI - Robot-assisted, single-site, dismembered pyeloplasty for ureteropelvic junction obstruction with the new da Vinci platform: a stage 2a study. SO - European Urology. 67(1):151-6, 2015 Jan AS - Eur Urol. 67(1):151-6, 2015 Jan NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Adult MH - Aged MH - Feasibility Studies MH - Female MH - Humans MH - *Kidney Pelvis/su [Surgery] MH - Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/is [Instrumentation] MH - *Laparoscopy/mt [Methods] MH - Length of Stay MH - Male MH - Middle Aged MH - Operative Time MH - Pilot Projects MH - Prospective Studies MH - Reoperation MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - Robotic Surgical Procedures/is [Instrumentation] MH - *Robotic Surgical Procedures/mt [Methods] MH - Treatment Outcome MH - *Ureter/su [Surgery] MH - *Ureteral Obstruction/su [Surgery] MH - Young Adult KW - Pyeloplasty; Robotic surgery; Single site; Ureteropelvic junction obstruction AB - BACKGROUND: Laparoendoscopic single-site surgery (LESS) has gained popularity in urology over the last few years. AB - OBJECTIVE: To report a stage 2a study of robot-assisted single-site (R-LESS) pyeloplasty for ureteropelvic junction obstruction (UPJO). AB - DESIGN, SETTING, AND PARTICIPANTS: This study is an investigative pilot study of 30 consecutive cases of R-LESS pyeloplasty performed at two participating institutions between July 2011 and September 2013. AB - SURGICAL PROCEDURE: Dismembered R-LESS pyeloplasty was performed at two surgical centers. AB - MEASUREMENTS: Feasibility (conversion rate), safety (complication rate and Clavien-Dindo classification), efficacy (clinical outcome) of the procedure were assessed. AB - RESULTS AND LIMITATIONS: The median patient age was 37 yr (range: 19-65 yr) and median body mass index was 23 kg/m(2) (range: 19-29 kg/m(2)). The median operative time was 160 min (range: 101-300 min), the median postoperative stay was 5 d (range: 3-13 d), and the median time to catheter removal was 3 d (range: 2-10). Two cases required conversion, the first one to standard laparoscopic technique and the second one to standard robotic technique. No intraoperative complications were reported. In three cases, an additional 5-mm trocar was needed. The postoperative complications rate was 26% (n=8). Most of them were grade 1 complications (n=4; 13%), followed by grade 2 (n=3; 10%) and grade 3 (n=1; 3.3%) complications, according to the Clavien-Dindo classification. One patient needed a surgical reintervention with standard robotic technique 3 d after surgery for urinary leakage. The overall success rate, considered as the resolution of symptoms and the absence of functional impairment at postoperative imaging, was 93.3% (n=28) at a median follow-up of 13 mo (range: 3-21 mo). The main limitations of this study are the limited number of patients included and the short-term follow-up. AB - CONCLUSIONS: Single-site robotic pyeloplasty is a feasible technique in selected patients, with good cosmetic results and excellent short-term clinical outcomes. Prospective studies are needed to further assess its role for the treatment of UPJO. AB - PATIENT SUMMARY: Single-site robot-assisted pyeloplasty is a feasible technique with good cosmetic results and excellent short-term clinical outcomes. AB - Copyright © 2014. Published by Elsevier B.V. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(14)00210-3 DO - https://dx.doi.org/10.1016/j.eururo.2014.03.001 PT - Clinical Trial PT - Journal Article PT - Multicenter Study ID - 24656756 [pubmed] ID - S0302-2838(14)00210-3 [pii] ID - 10.1016/j.eururo.2014.03.001 [doi] PP - ppublish PH - 2014/01/17 [received] PH - 2014/03/03 [accepted] LG - English EP - 20140313 DP - 2015 Jan DC - 20141203 EZ - 2014/03/25 06:00 DA - 2015/07/29 06:00 DT - 2014/03/25 06:00 YR - 2015 ED - 20150728 RD - 20151026 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24656756 <174. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25045857 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lonnerfors C AU - Reynisson P AU - Persson J FA - Lonnerfors, Celine FA - Reynisson, Petur FA - Persson, Jan IN - Lonnerfors, Celine. Department of Obstetrics and Gynecology, Skane University Hospital and Lund University, Lund, Sweden. IN - Reynisson, Petur. Department of Obstetrics and Gynecology, Skane University Hospital and Lund University, Lund, Sweden. IN - Persson, Jan. Department of Obstetrics and Gynecology, Skane University Hospital and Lund University, Lund, Sweden. Electronic address: jan.persson@med.lu.se. TI - A randomized trial comparing vaginal and laparoscopic hysterectomy vs robot-assisted hysterectomy. SO - Journal of Minimally Invasive Gynecology. 22(1):78-86, 2015 Jan AS - J Minim Invasive Gynecol. 22(1):78-86, 2015 Jan NJ - Journal of minimally invasive gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101235322 IO - J Minim Invasive Gynecol SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Female MH - *Hospital Costs MH - Humans MH - Hysterectomy/ec [Economics] MH - Hysterectomy/mt [Methods] MH - Hysterectomy, Vaginal/ec [Economics] MH - *Hysterectomy, Vaginal/mt [Methods] MH - Laparoscopy/ec [Economics] MH - Laparoscopy/mt [Methods] MH - Middle Aged MH - Postoperative Complications/ec [Economics] MH - *Postoperative Complications/ep [Epidemiology] MH - Robotic Surgical Procedures/ec [Economics] MH - *Robotic Surgical Procedures/mt [Methods] MH - Treatment Outcome KW - Hysterectomy; Laparoscopic hysterectomy; Minimally invasive surgery; Robot-assisted laparoscopy; Vaginal hysterectomy AB - STUDY OBJECTIVE: To investigate the hospital cost and short-term clinical outcome of traditional minimally invasive hysterectomy vs robot-assisted hysterectomy in women primarily not considered candidates for vaginal surgery. AB - DESIGN: Randomized controlled trial (Canadian Task Force classification I). AB - SETTING: University Hospital in Sweden. AB - PATIENTS: One hundred twenty-two women with uterine size < 16 gestational weeks scheduled to undergo minimally invasive hysterectomy because of benign disease. AB - INTERVENTIONS: Robot-assisted hysterectomy or traditional vaginal or laparoscopic minimally invasive hysterectomy. AB - MEASUREMENTS AND MAIN RESULTS: All women underwent surgery as randomized. There were no demographic differences between the 2 groups. Vaginal hysterectomy was possible in 41% in the traditional minimally invasive group, at a mean hospital cost of $4579 compared with $7059 for traditional laparoscopic hysterectomy. This was reflected in a mean hospital cost of $993 more per robotic-assisted hysterectomy than for traditional minimally invasive hysterectomy when the robot was a preexisting investment. This hospital cost increased by $1607 when including investments and cost of maintenance. A per-protocol subanalysis comparing laparoscopy and robotics demonstrated similar hospital cost when the robot was a preexisting investment ($7059 vs $7016). Robotic-assisted hysterectomy was associated with less blood loss and fewer postoperative complications. AB - CONCLUSION: A similar hospital cost can be attained for laparoscopy and robotics when the robot is a preexisting investment. From the perspective of hospital costs, robotic-assisted hysterectomy is not advantageous for treating benign conditions when a vaginal approach is feasible in a high proportion of patients. AB - Copyright © 2015 AAGL. Published by Elsevier Inc. All rights reserved. ES - 1553-4669 IL - 1553-4650 DI - S1553-4650(14)00400-2 DO - https://dx.doi.org/10.1016/j.jmig.2014.07.010 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 25045857 [pubmed] ID - S1553-4650(14)00400-2 [pii] ID - 10.1016/j.jmig.2014.07.010 [doi] PP - ppublish PH - 2014/06/18 [received] PH - 2014/07/09 [revised] PH - 2014/07/12 [accepted] LG - English EP - 20140719 DP - 2015 Jan DC - 20141226 EZ - 2014/07/22 06:00 DA - 2015/07/23 06:00 DT - 2014/07/22 06:00 YR - 2015 ED - 20150722 RD - 20141226 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25045857 <175. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25463766 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Parisi A AU - Desiderio J AU - Trastulli S AU - Cirocchi R AU - Ricci F AU - Farinacci F AU - Mangia A AU - Boselli C AU - Noya G AU - Filippini A AU - D'Andrea V AU - Santoro A FA - Parisi, Amilcare FA - Desiderio, Jacopo FA - Trastulli, Stefano FA - Cirocchi, Roberto FA - Ricci, Francesco FA - Farinacci, Federico FA - Mangia, Antongiulio FA - Boselli, Carlo FA - Noya, Giuseppe FA - Filippini, Angelo FA - D'Andrea, Vito FA - Santoro, Alberto IN - Parisi, Amilcare. Department of Digestive Surgery and Liver Unit, St. Maria Hospital, Terni, Italy. Electronic address: amilcareparisi@virgilio.it. IN - Desiderio, Jacopo. Department of Digestive Surgery and Liver Unit, St. Maria Hospital, Terni, Italy. Electronic address: djdesi85@hotmail.it. IN - Trastulli, Stefano. Department of Digestive Surgery and Liver Unit, St. Maria Hospital, Terni, Italy. Electronic address: chirdig@libero.it. IN - Cirocchi, Roberto. Department of Digestive Surgery and Liver Unit, St. Maria Hospital, Terni, Italy. Electronic address: cirocchiroberto@yahoo.it. IN - Ricci, Francesco. Department of Digestive Surgery and Liver Unit, St. Maria Hospital, Terni, Italy. Electronic address: f.fricci@libero.it. IN - Farinacci, Federico. Department of Digestive Surgery and Liver Unit, St. Maria Hospital, Terni, Italy. Electronic address: fedrico.farinacci@gmail.com. IN - Mangia, Antongiulio. Department of General and Oncologic Surgery, University of Perugia, Perugia, Italy. Electronic address: giulio116@hotmail.it. IN - Boselli, Carlo. Department of General and Oncologic Surgery, University of Perugia, Perugia, Italy. Electronic address: carloboselli@yahoo.it. IN - Noya, Giuseppe. Department of General and Oncologic Surgery, University of Perugia, Perugia, Italy. Electronic address: gnoya@unipg.it. IN - Filippini, Angelo. Department of Surgical Sciences, Sapienza University of Rome, Rome, Italy. Electronic address: angelo.filippini@uniroma1.it. IN - D'Andrea, Vito. Department of Surgical Sciences, Sapienza University of Rome, Rome, Italy. Electronic address: vito.dandrea@uniroma1.it. IN - Santoro, Alberto. Department of Surgical Sciences, Sapienza University of Rome, Rome, Italy. Electronic address: albert.santoro@tiscali.it. TI - Robotic rectal resection for cancer: a prospective cohort study to analyze surgical, clinical and oncological outcomes. SO - International Journal Of Surgery. 12(12):1456-61, 2014 Dec AS - Int J Surg. 12(12):1456-61, 2014 Dec NJ - International journal of surgery (London, England) PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101228232 IO - Int J Surg SB - Index Medicus CP - England MH - Adult MH - Aged MH - Cohort Studies MH - Digestive System Surgical Procedures/mt [Methods] MH - Female MH - Humans MH - Italy MH - Laparoscopy/mt [Methods] MH - Length of Stay MH - Lymph Node Excision MH - Male MH - Middle Aged MH - Operative Time MH - Postoperative Complications/su [Surgery] MH - Prospective Studies MH - *Rectal Neoplasms/su [Surgery] MH - *Rectum/su [Surgery] MH - Robotic Surgical Procedures/ae [Adverse Effects] MH - *Robotic Surgical Procedures KW - Rectal cancer; Robotic mesorectal excision; Robotic surgery AB - AIM: Robotic systems are getting widely spread in recent years given the different technical advantages over traditional laparoscopy. Rectal surgery seems to benefit from this approach, for its ability to easily work in a confined space such as the pelvic cavity. The objective is to present results obtained by the robotic approach in patients with rectal cancer and to give technical considerations. AB - METHOD: Data were prospectively collected in order to evaluate surgical and oncological outcomes. Subjects underwent robotic rectal resection in the period between June 2011 and June 2014 at the Department of Digestive Surgery, "S. Maria" Hospital - Terni (Italy). AB - MAIN OUTCOME MEASURES: Patient characteristics and tumor, overall operative time, conversion to open surgery, site of mini-laparotomy for specimen extraction, intraoperative blood loss, intraoperative complications, time to first bowel movement, time-to-liquid and solid intake, postoperative complications, mortality, hospital stay, thirty-day complications, histopathological examination. AB - RESULTS: 40 consecutive patients underwent robotic resection of the rectum. Median operative time was 340 min (235-460 min), no procedure was converted. Median hospital stay was 5 days (3-18 days). Mesorectum resection was complete in all patients. Median number of harvested lymph nodes was 19 (6-35), median distal resection margin was 4 cm (2-8 cm). AB - CONCLUSION: Robotic rectal surgery is safe and feasible in particular by facilitating the surgeon during the delicate phases of tissue dissection. AB - Copyright © 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved. ES - 1743-9159 IL - 1743-9159 DI - S1743-9191(14)00972-8 DO - https://dx.doi.org/10.1016/j.ijsu.2014.11.012 PT - Journal Article ID - 25463766 [pubmed] ID - S1743-9191(14)00972-8 [pii] ID - 10.1016/j.ijsu.2014.11.012 [doi] PP - ppublish PH - 2014/10/05 [received] PH - 2014/11/09 [revised] PH - 2014/11/11 [accepted] LG - English EP - 20141113 DP - 2014 Dec DC - 20141222 EZ - 2014/12/03 06:00 DA - 2015/07/15 06:00 DT - 2014/12/03 06:00 YR - 2014 ED - 20150714 RD - 20141222 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25463766 <176. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24894202 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Botros C AU - Lewis C AU - Culligan P AU - Salamon C FA - Botros, Carolyn FA - Lewis, Christa FA - Culligan, Patrick FA - Salamon, Charbel IN - Botros, Carolyn. Division of Urogynecology and Reconstructive Pelvic Surgery, Atlantic Health System, Morristown, NJ, USA. TI - A prospective study of a single-incision sling at the time of robotic sacrocolpopexy. SO - International Urogynecology Journal. 25(11):1541-6, 2014 Nov AS - Int Urogynecol J Pelvic Floor Dysfunct. 25(11):1541-6, 2014 Nov NJ - International urogynecology journal PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - cl5, 9514583, 101567041 IO - Int Urogynecol J PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190456 SB - Index Medicus CP - England MH - Aged MH - Female MH - Follow-Up Studies MH - Humans MH - Middle Aged MH - Pelvic Organ Prolapse/co [Complications] MH - Pelvic Organ Prolapse/su [Surgery] MH - Prospective Studies MH - Reoperation MH - Robotic Surgical Procedures MH - Sacrum/su [Surgery] MH - Severity of Illness Index MH - *Suburethral Slings MH - Surveys and Questionnaires MH - Treatment Outcome MH - Urinary Incontinence, Stress/co [Complications] MH - *Urinary Incontinence, Stress/su [Surgery] MH - Vagina/su [Surgery] AB - INTRODUCTION AND HYPOTHESIS: The objective of this study was to evaluate the efficacy and safety of the Miniarc Precise single-incision sling (American Medical Systems, Minnetonka, MN, USA) placed at the time of a robotic sacrocolpopexy. AB - METHODS: This was a prospective study of a single-incision suburethral sling placed at the time of robotic sacrocolpopexy in women with stress urinary incontinence (SUI) and pelvic organ prolapse. Primary outcome measure was cure at 1 year, defined objectively by a negative cough stress test (CST) and subjectively by a score of "0 or 1" on question 17 of the Pelvic Floor Distress Inventory (PFDI-20): "Do you experience urine leakage related to coughing/sneezing/laughing?" Secondary outcome measures included the change in Urinary Distress Inventory (UDI-6) and Urinary Impact Questionnaire (UIQ-7) scores at 1 year. All sling-related complications were reported. Paired Student's t test and the Wilcoxon signed-rank test were used for statistical analysis. AB - RESULTS: One hundred and one patients were included between August 2010 and July 2012. One-year follow-up was available for 97 out of 101 patients (96 %). Objective cure was 90 % and subjective cure was 87 %. Baseline UDI-6 scores improved from 34.8+/-25.1 to 6.7+/-11.2 at 1 year (p<0.001). Similarly, UIQ-7 scores improved from 21.1+/-22.8 to 2.4+/-8.2 at 1 year (p<0.001). There were no intraoperative cystotomies, no mesh erosions, no sling revisions, and no cases of urinary retention. The retreatment rate for persistent SUI was 8 % (8 out of 97). AB - CONCLUSIONS: The addition of a single-incision suburethral sling at the time of robotic sacrocolpopexy in women with SUI resulted in an 87 % cure rate at 1 year. ES - 1433-3023 IL - 0937-3462 DO - https://dx.doi.org/10.1007/s00192-014-2432-8 PT - Clinical Trial PT - Journal Article ID - 24894202 [pubmed] ID - 10.1007/s00192-014-2432-8 [doi] ID - PMC4190456 [pmc] PP - ppublish PH - 2014/02/06 [received] PH - 2014/05/01 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01982188 SL - https://clinicaltrials.gov/search/term=NCT01982188 LG - English EP - 20140604 DP - 2014 Nov DC - 20141009 EZ - 2014/06/05 06:00 DA - 2015/07/15 06:00 DT - 2014/06/05 06:00 YR - 2014 ED - 20150708 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24894202 <177. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24894202 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Botros C AU - Lewis C AU - Culligan P AU - Salamon C FA - Botros, Carolyn FA - Lewis, Christa FA - Culligan, Patrick FA - Salamon, Charbel IN - Botros, Carolyn. Division of Urogynecology and Reconstructive Pelvic Surgery, Atlantic Health System, Morristown, NJ, USA. TI - A prospective study of a single-incision sling at the time of robotic sacrocolpopexy. SO - International Urogynecology Journal. 25(11):1541-6, 2014 Nov AS - Int Urogynecol J Pelvic Floor Dysfunct. 25(11):1541-6, 2014 Nov NJ - International urogynecology journal PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - cl5, 9514583, 101567041 IO - Int Urogynecol J PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190456 SB - Index Medicus CP - England MH - Aged MH - Female MH - Follow-Up Studies MH - Humans MH - Middle Aged MH - Pelvic Organ Prolapse/co [Complications] MH - Pelvic Organ Prolapse/su [Surgery] MH - Prospective Studies MH - Reoperation MH - Robotic Surgical Procedures MH - Sacrum/su [Surgery] MH - Severity of Illness Index MH - *Suburethral Slings MH - Surveys and Questionnaires MH - Treatment Outcome MH - Urinary Incontinence, Stress/co [Complications] MH - *Urinary Incontinence, Stress/su [Surgery] MH - Vagina/su [Surgery] AB - INTRODUCTION AND HYPOTHESIS: The objective of this study was to evaluate the efficacy and safety of the Miniarc Precise single-incision sling (American Medical Systems, Minnetonka, MN, USA) placed at the time of a robotic sacrocolpopexy. AB - METHODS: This was a prospective study of a single-incision suburethral sling placed at the time of robotic sacrocolpopexy in women with stress urinary incontinence (SUI) and pelvic organ prolapse. Primary outcome measure was cure at 1 year, defined objectively by a negative cough stress test (CST) and subjectively by a score of "0 or 1" on question 17 of the Pelvic Floor Distress Inventory (PFDI-20): "Do you experience urine leakage related to coughing/sneezing/laughing?" Secondary outcome measures included the change in Urinary Distress Inventory (UDI-6) and Urinary Impact Questionnaire (UIQ-7) scores at 1 year. All sling-related complications were reported. Paired Student's t test and the Wilcoxon signed-rank test were used for statistical analysis. AB - RESULTS: One hundred and one patients were included between August 2010 and July 2012. One-year follow-up was available for 97 out of 101 patients (96 %). Objective cure was 90 % and subjective cure was 87 %. Baseline UDI-6 scores improved from 34.8+/-25.1 to 6.7+/-11.2 at 1 year (p<0.001). Similarly, UIQ-7 scores improved from 21.1+/-22.8 to 2.4+/-8.2 at 1 year (p<0.001). There were no intraoperative cystotomies, no mesh erosions, no sling revisions, and no cases of urinary retention. The retreatment rate for persistent SUI was 8 % (8 out of 97). AB - CONCLUSIONS: The addition of a single-incision suburethral sling at the time of robotic sacrocolpopexy in women with SUI resulted in an 87 % cure rate at 1 year. ES - 1433-3023 IL - 0937-3462 DO - https://dx.doi.org/10.1007/s00192-014-2432-8 PT - Clinical Trial PT - Journal Article ID - 24894202 [pubmed] ID - 10.1007/s00192-014-2432-8 [doi] ID - PMC4190456 [pmc] PP - ppublish PH - 2014/02/06 [received] PH - 2014/05/01 [accepted] LG - English EP - 20140604 DP - 2014 Nov DC - 20141009 EZ - 2014/06/05 06:00 DA - 2015/07/15 06:00 DT - 2014/06/05 06:00 YR - 2014 ED - 20150708 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=24894202 <178. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25454974 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Seo HS AU - Shim JH AU - Jeon HM AU - Park CH AU - Song KY FA - Seo, Ho Seok FA - Shim, Jung Ho FA - Jeon, Hae Myung FA - Park, Cho Hyun FA - Song, Kyo Young IN - Seo, Ho Seok. Division of Gastrointestinal Surgery, Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. IN - Shim, Jung Ho. Division of Gastrointestinal Surgery, Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. IN - Jeon, Hae Myung. Division of Gastrointestinal Surgery, Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. IN - Park, Cho Hyun. Division of Gastrointestinal Surgery, Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. IN - Song, Kyo Young. Division of Gastrointestinal Surgery, Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. Electronic address: skygs@catholic.ac.kr. TI - Postoperative pancreatic fistula after robot distal gastrectomy. SO - Journal of Surgical Research. 194(2):361-6, 2015 Apr AS - J Surg Res. 194(2):361-6, 2015 Apr NJ - The Journal of surgical research PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - k7b, 0376340 IO - J. Surg. Res. SB - Index Medicus CP - United States MH - Female MH - *Gastrectomy/ae [Adverse Effects] MH - *Gastrectomy/mt [Methods] MH - Humans MH - Laparoscopy MH - Male MH - Middle Aged MH - *Pancreatic Fistula/et [Etiology] MH - *Postoperative Complications/et [Etiology] MH - Risk Factors MH - *Robotics KW - Gastric cancer; Laparoscopic-assisted distal gastrectomy; Postoperative pancreatic fistula; Robot-assisted distal gastrectomy AB - BACKGROUND: To compare the incidences of postoperative pancreatic fistula (POPF) between robot-assisted distal gastrectomy (RADG) and laparoscopy-assisted distal gastrectomy (LADG). AB - MATERIALS AND METHODS: A total of 40 patients with gastric cancer who underwent RADG were compared with 40 initial patients who underwent LADG by a single surgeon. We evaluated and compared the clinicopathologic characteristics, surgical outcomes, and operative complications including POPF in two groups. AB - RESULTS: The POPF was observed more frequently in the LADG group than in the RADG group (22.5% versus 10%, P < 0.001). Although the serum amylase levels in the 20 first-half cases did not statistically differ between LADG and RADG (P = 0.32), those in the 20 latter-half cases were significantly lower in the RADG group (P < 0.05). Univariate and multivariate analyses identified laparoscopic surgery and visceral fat area as POPF-associated risk factors. AB - CONCLUSIONS: RADG is feasible and safe for distal gastrectomy in terms of POPF. AB - Copyright © 2015 Elsevier Inc. All rights reserved. ES - 1095-8673 IL - 0022-4804 DI - S0022-4804(14)00962-7 DO - https://dx.doi.org/10.1016/j.jss.2014.10.022 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 25454974 [pubmed] ID - S0022-4804(14)00962-7 [pii] ID - 10.1016/j.jss.2014.10.022 [doi] PP - ppublish PH - 2014/07/15 [received] PH - 2014/09/09 [revised] PH - 2014/10/17 [accepted] LG - English EP - 20141022 DP - 2015 Apr DC - 20150316 EZ - 2014/12/03 06:00 DA - 2015/07/03 06:00 DT - 2014/12/03 06:00 YR - 2015 ED - 20150702 RD - 20150316 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25454974 <179. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24924314 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Liss MA AU - Morales B AU - Skarecky D AU - Ahlering TE FA - Liss, Michael A FA - Morales, Blanca FA - Skarecky, Douglas FA - Ahlering, Thomas E IN - Liss, Michael A. Department of Urology, University of California , Irvine, Orange, California. TI - Phase 1 clinical trial of VesicareTM (solifenacin) in the treatment of urinary incontinence after radical prostatectomy. SO - Journal of Endourology. 28(10):1241-5, 2014 Oct AS - J Endourol. 28(10):1241-5, 2014 Oct NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Aged MH - Humans MH - Male MH - Middle Aged MH - *Muscarinic Antagonists/tu [Therapeutic Use] MH - Pilot Projects MH - Prospective Studies MH - *Prostatectomy/ae [Adverse Effects] MH - *Prostatic Neoplasms/su [Surgery] MH - *Quinuclidines/tu [Therapeutic Use] MH - *Robotic Surgical Procedures/ae [Adverse Effects] MH - Solifenacin Succinate MH - *Tetrahydroisoquinolines/tu [Therapeutic Use] MH - Treatment Outcome MH - *Urinary Incontinence/dt [Drug Therapy] MH - Urinary Incontinence/et [Etiology] AB - PURPOSE: Permanent and prolonged incontinence following robot assisted radical prostatectomy (RARP) is known to result from injury to the external sphincter. We hypothesize that pre-existing detrusor overactivity may also contribute to delayed return of continence (>3 months). This pilot study examines the safety profile and efficacy of muscarinic receptor antagonist, solifenacin, in incontinent men after prostatectomy. AB - MATERIALS AND METHODS: Men using three or more pads 7 days post catheter removal were invited to enroll into the study (5mg daily of solifenacin for 3 months). All subjects received RARP under hypothermic conditions by one surgeon. Continence was defined as 0 pads. AB - RESULTS: Forty men were enrolled, one excluded due to missing follow-up. Two men reported nonserious adverse events: one a vaso-vagal reaction when taking solifenacin with sildenafil, and the other was dehydration and dizziness after strenuous exercise. Additionally, four withdrew due to side effects. The efficacy outcomes show improved intermittency after prostatectomy, though unclear if due to the medication. At 3 months, 21 patients (53.8%) reached the primary continence outcome of zero pads. The median time to continence in this group was 95 days. AB - CONCLUSIONS: Solifenacin is well tolerated in post radical prostatectomy patients with a 15% withdrawal rate due to side effects. These results formed the basis of a large, prospectively randomized clinical trial comparing the effects of solifenacin versus placebo in a population of men incontinent after RARP. RN - 0 (Muscarinic Antagonists) RN - 0 (Quinuclidines) RN - 0 (Tetrahydroisoquinolines) RN - KKA5DLD701 (Solifenacin Succinate) ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2014.0342 PT - Clinical Trial, Phase I PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 24924314 [pubmed] ID - 10.1089/end.2014.0342 [doi] PP - ppublish LG - English EP - 20140721 DP - 2014 Oct DC - 20141003 EZ - 2014/06/14 06:00 DA - 2015/07/03 06:00 DT - 2014/06/14 06:00 YR - 2014 ED - 20150702 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24924314 <180. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25771249 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ngandu T AU - Lehtisalo J AU - Solomon A AU - Levalahti E AU - Ahtiluoto S AU - Antikainen R AU - Backman L AU - Hanninen T AU - Jula A AU - Laatikainen T AU - Lindstrom J AU - Mangialasche F AU - Paajanen T AU - Pajala S AU - Peltonen M AU - Rauramaa R AU - Stigsdotter-Neely A AU - Strandberg T AU - Tuomilehto J AU - Soininen H AU - Kivipelto M FA - Ngandu, Tiia FA - Lehtisalo, Jenni FA - Solomon, Alina FA - Levalahti, Esko FA - Ahtiluoto, Satu FA - Antikainen, Riitta FA - Backman, Lars FA - Hanninen, Tuomo FA - Jula, Antti FA - Laatikainen, Tiina FA - Lindstrom, Jaana FA - Mangialasche, Francesca FA - Paajanen, Teemu FA - Pajala, Satu FA - Peltonen, Markku FA - Rauramaa, Rainer FA - Stigsdotter-Neely, Anna FA - Strandberg, Timo FA - Tuomilehto, Jaakko FA - Soininen, Hilkka FA - Kivipelto, Miia IN - Ngandu, Tiia. Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Karolinska Institutet Center for Alzheimer Research, Stockholm, Sweden. IN - Lehtisalo, Jenni. Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland. IN - Solomon, Alina. Karolinska Institutet Center for Alzheimer Research, Stockholm, Sweden; Institute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland; Aging Research Center, Karolinska Institutet-Stockholm University, Stockholm, Sweden. IN - Levalahti, Esko. Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland. IN - Ahtiluoto, Satu. Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland. IN - Antikainen, Riitta. Institute of Health Sciences/Geriatrics, University of Oulu and Oulu University Hospital, Oulu, Finland; Medical Research Center Oulu, Oulu University Hospital, Oulu, Finland; Oulu City Hospital, Oulu, Finland. IN - Backman, Lars. Aging Research Center, Karolinska Institutet-Stockholm University, Stockholm, Sweden. IN - Hanninen, Tuomo. Department of Neurology, Kuopio University Hospital, Kuopio, Finland. IN - Jula, Antti. Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland. IN - Laatikainen, Tiina. Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland. IN - Lindstrom, Jaana. Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland. IN - Mangialasche, Francesca. Aging Research Center, Karolinska Institutet-Stockholm University, Stockholm, Sweden. IN - Paajanen, Teemu. Finnish Institute of Occupational Health, Helsinki, Finland. IN - Pajala, Satu. Welfare and Health Promotion Unit, National Institute for Health and Welfare, Helsinki, Finland. IN - Peltonen, Markku. Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland. IN - Rauramaa, Rainer. Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland. IN - Stigsdotter-Neely, Anna. Department of Psychology, Umea University, Umea, Sweden. IN - Strandberg, Timo. Institute of Health Sciences/Geriatrics, University of Oulu and Oulu University Hospital, Oulu, Finland; Department of Medicine, Geriatric Clinic, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland. IN - Tuomilehto, Jaakko. Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Department of Public Health, HJELT Institute, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland; South Ostrobothnia Central Hospital, Seinajoki, Finland; Center for Vascular Prevention, Danube-University Krems, Krems, Austria; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia. IN - Soininen, Hilkka. Institute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland; Department of Neurology, Kuopio University Hospital, Kuopio, Finland. IN - Kivipelto, Miia. Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Karolinska Institutet Center for Alzheimer Research, Stockholm, Sweden; Institute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland; Aging Research Center, Karolinska Institutet-Stockholm University, Stockholm, Sweden. Electronic address: miia.kivipelto@ki.se. TI - A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial. CM - Comment in: Mov Disord. 2016 Mar;31(3):299; PMID: 26688322 CM - Comment in: Lancet. 2015 Oct 24;386(10004):1626-7; PMID: 26595629 CM - Comment in: Lancet. 2015 Oct 24;386(10004):1625-6; PMID: 26595628 CM - Comment in: Lancet. 2015 Oct 24;386(10004):1627; PMID: 26595631 CM - Comment in: Nat Rev Neurol. 2015 May;11(5):248; PMID: 25799934 SO - Lancet. 385(9984):2255-63, 2015 Jun 06 AS - Lancet. 385(9984):2255-63, 2015 Jun 06 NJ - Lancet (London, England) PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 2985213r, l0s, 0053266 IO - Lancet SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - Aged MH - Cognition Disorders/ep [Epidemiology] MH - *Cognition Disorders/pc [Prevention & Control] MH - *Diet MH - Double-Blind Method MH - *Exercise MH - *Exercise Therapy MH - Humans MH - Male MH - Middle Aged MH - Neuropsychological Tests MH - Risk Assessment MH - *Vascular Diseases/ep [Epidemiology] MH - Vascular Diseases/pc [Prevention & Control] AB - BACKGROUND: Modifiable vascular and lifestyle-related risk factors have been associated with dementia risk in observational studies. In the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER), a proof-of-concept randomised controlled trial, we aimed to assess a multidomain approach to prevent cognitive decline in at-risk elderly people from the general population. AB - METHODS: In a double-blind randomised controlled trial we enrolled individuals aged 60-77 years recruited from previous national surveys. Inclusion criteria were CAIDE (Cardiovascular Risk Factors, Aging and Dementia) Dementia Risk Score of at least 6 points and cognition at mean level or slightly lower than expected for age. We randomly assigned participants in a 1:1 ratio to a 2 year multidomain intervention (diet, exercise, cognitive training, vascular risk monitoring), or a control group (general health advice). Computer-generated allocation was done in blocks of four (two individuals randomly allocated to each group) at each site. Group allocation was not actively disclosed to participants and outcome assessors were masked to group allocation. The primary outcome was change in cognition as measured through comprehensive neuropsychological test battery (NTB) Z score. Analysis was by modified intention to treat (all participants with at least one post-baseline observation). This trial is registered at ClinicalTrials.gov, number NCT01041989. AB - FINDINGS: Between Sept 7, 2009, and Nov 24, 2011, we screened 2654 individuals and randomly assigned 1260 to the intervention group (n=631) or control group (n=629). 591 (94%) participants in the intervention group and 599 (95%) in the control group had at least one post-baseline assessment and were included in the modified intention-to-treat analysis. Estimated mean change in NTB total Z score at 2 years was 0.20 (SE 0.02, SD 0.51) in the intervention group and 0.16 (0.01, 0.51) in the control group. Between-group difference in the change of NTB total score per year was 0.022 (95% CI 0.002-0.042, p=0.030). 153 (12%) individuals dropped out overall. Adverse events occurred in 46 (7%) participants in the intervention group compared with six (1%) participants in the control group; the most common adverse event was musculoskeletal pain (32 [5%] individuals for intervention vs no individuals for control). AB - INTERPRETATION: Findings from this large, long-term, randomised controlled trial suggest that a multidomain intervention could improve or maintain cognitive functioning in at-risk elderly people from the general population. AB - FUNDING: Academy of Finland, La Carita Foundation, Alzheimer Association, Alzheimer's Research and Prevention Foundation, Juho Vainio Foundation, Novo Nordisk Foundation, Finnish Social Insurance Institution, Ministry of Education and Culture, Salama bint Hamdan Al Nahyan Foundation, Axa Research Fund, EVO funding for University Hospitals of Kuopio, Oulu, and Turku and for Seinajoki Central Hospital and Oulu City Hospital, Swedish Research Council, Swedish Research Council for Health, Working Life and Welfare, and af Jochnick Foundation. AB - Copyright © 2015 Elsevier Ltd. All rights reserved. ES - 1474-547X IL - 0140-6736 DI - S0140-6736(15)60461-5 DO - https://dx.doi.org/10.1016/S0140-6736(15)60461-5 PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 25771249 [pubmed] ID - S0140-6736(15)60461-5 [pii] ID - 10.1016/S0140-6736(15)60461-5 [doi] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01041989 SL - https://clinicaltrials.gov/search/term=NCT01041989 LG - English EP - 20150312 DP - 2015 Jun 06 DC - 20150619 EZ - 2015/03/16 06:00 DA - 2015/07/02 06:00 DT - 2015/03/17 06:00 YR - 2015 ED - 20150701 RD - 20160707 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25771249 <181. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25179979 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Zhe Z AU - Kun H AU - Xuezeng X AU - Yunge C AU - Zengshan M AU - Huiming G AU - Liming L AU - Liang T AU - Zhiwei W AU - Hansong S AU - Shengshou H FA - Zhe, Zheng FA - Kun, Hua FA - Xuezeng, Xu FA - Yunge, Chen FA - Zengshan, Ma FA - Huiming, Guo FA - Liming, Liu FA - Liang, Tiao FA - Zhiwei, Wang FA - Hansong, Sun FA - Shengshou, Hu IN - Zhe, Zheng. Department of Cardiac Surgery, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijin, 100037, People's Republic of China. IN - Kun, Hua. Department of Cardiac Surgery, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijin, 100037, People's Republic of China. IN - Xuezeng, Xu. Institute of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China. IN - Yunge, Chen. Department of Cardiovascular Surgery, Shanghai Yodak Cardiothoracic Hospital, Shanghai, China. IN - Zengshan, Ma. Department of Cardiac Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China. IN - Huiming, Guo. Department of Cardiovascular Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China. IN - Liming, Liu. Department of Cardiothoracic Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China. IN - Liang, Tiao. Department of Cardiovascular Surgery, Wu Han YaXin Hospital, Wuhan, China. IN - Zhiwei, Wang. Department of Thoracic & Cardiovascular Surgery, Affiliated Hospital of Wu Han University, Wuhan, China. IN - Hansong, Sun. Department of Cardiac Surgery, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijin, 100037, People's Republic of China. IN - Shengshou, Hu. Department of Cardiac Surgery, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijin, 100037, People's Republic of China. TI - Totally thoracoscopic versus open surgery for closure of atrial septal defect: propensity-score matched comparison. SO - Heart Surgery Forum. 17(4):E227-31, 2014 Aug AS - Heart Surg Forum. 17(4):E227-31, 2014 Aug NJ - The heart surgery forum PI - Journal available in: Print PI - Citation processed from: Internet JC - duc, 100891112 IO - Heart Surg Forum SB - Index Medicus CP - United States MH - Adult MH - *Cardiovascular Surgical Procedures/mo [Mortality] MH - China/ep [Epidemiology] MH - Female MH - *Heart Septal Defects, Atrial/mo [Mortality] MH - *Heart Septal Defects, Atrial/su [Surgery] MH - Humans MH - *Length of Stay/sn [Statistics & Numerical Data] MH - Male MH - *Operative Time MH - Prevalence MH - Risk Factors MH - Survival Rate MH - Thoracoscopy/mt [Methods] MH - *Thoracoscopy/mo [Mortality] MH - Treatment Outcome AB - The purpose of this study is to compare early clinical outcomes of surgical repair for isolated atrial septal defect (ASD) with a totally thoracoscopic approach without robotic assistance versus a conventional open procedure.Between September 2010 and June 2012, 254 consecutive patients with isolated ASD underwent totally thoracoscopic surgery without robotic assistance in seven institutions participating in the nationwide multi-centered registry in China. During the same period, these patients were matched using propensity score methodology with 254 patients who had accepted conventional open surgery through a median sternotomy. The early in-hospital results between the two groups were analyzed and compared.The patient age was 26.8 +/- 14.0 years and weight was 52.9 +/- 16.9 kg in the totally thoracoscopic group. The totally thoracoscopic surgery required longer aortic clamp time (32.1 +/- 17.3 minutes versus 28.3 +/- 16.7 minutes, P = .01); shorter length of stay in the intensive care unit (25.3 +/- 12.2 hours versus 34.8 +/- 24.4 hours, P = .001); shorter length of stay in hospital (6.5 +/- 6.3 days versus 7.9 +/- 6.4 days, P = .008); and shorter mechanical ventilation time (8.3 +/- 5.0 hours versus 11.4 +/- 14.8 hours, P = .04). The cardiopulmonary bypass (CPB) time (62.7 +/- 29.3 minutes versus 61.5 +/- 28.0 minutes, P = .64) showed no significant difference between the two groups. The totally thoracoscopic group had significantly less postoperative chest tube drainage (322.1 +/- 213.7 mL versus 462.8 +/- 398.4 mL, P = .001). The intraoperative (35.4% versus 38.6%, P = .46) and postoperative blood products usage (20.9% versus 21.3%, P = .91) showed no significant difference between the two groups.There also was no significant difference in mortality and major in-hospital complications between the two groups. The early outcomes for treatment of isolated ASD were similar between the totally thoracoscopic group conventional open operation performed through median sternotomy, despite a longer aortic clamp time in the totally thoracoscopic group. ES - 1522-6662 IL - 1098-3511 DI - PG71V52135820723 DO - https://dx.doi.org/10.1532/HSF98.2014382 PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 25179979 [pubmed] ID - PG71V52135820723 [pii] ID - 10.1532/HSF98.2014382 [doi] PP - ppublish LG - English DP - 2014 Aug DC - 20140902 EZ - 2014/09/03 06:00 DA - 2015/07/01 06:00 DT - 2014/09/03 06:00 YR - 2014 ED - 20150630 RD - 20140902 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25179979 <182. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25444990 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Raz O AU - Boesel TW AU - Arianayagam M AU - Lau H AU - Vass J AU - Huynh CC AU - Graham SL AU - Varol C FA - Raz, Orit FA - Boesel, Tillman W FA - Arianayagam, Mohan FA - Lau, Howard FA - Vass, Justin FA - Huynh, Chi Can FA - Graham, Stuart L FA - Varol, Celi IN - Raz, Orit. Department of Urology, Macquarie University Hospital, Australian School of Advanced Medicine, Sydney, New South Wales, Australia. Electronic address: droritraz@yahoo.com. IN - Boesel, Tillman W. Department of Anesthesiology, Macquarie University Hospital, Australian School of Advanced Medicine, Sydney, New South Wales, Australia. IN - Arianayagam, Mohan. Department of Urology, Macquarie University Hospital, Australian School of Advanced Medicine, Sydney, New South Wales, Australia. IN - Lau, Howard. Department of Urology, Macquarie University Hospital, Australian School of Advanced Medicine, Sydney, New South Wales, Australia. IN - Vass, Justin. Department of Urology, Macquarie University Hospital, Australian School of Advanced Medicine, Sydney, New South Wales, Australia. IN - Huynh, Chi Can. Department of Urology, Macquarie University Hospital, Australian School of Advanced Medicine, Sydney, New South Wales, Australia. IN - Graham, Stuart L. Department of Ophthalmology, Macquarie University Hospital, Australian School of Advanced Medicine, Sydney, New South Wales, Australia. IN - Varol, Celi. Department of Urology, Macquarie University Hospital, Australian School of Advanced Medicine, Sydney, New South Wales, Australia. TI - The effect of the modified Z trendelenburg position on intraocular pressure during robotic assisted laparoscopic radical prostatectomy: a randomized, controlled study. SO - Journal of Urology. 193(4):1213-9, 2015 Apr AS - J Urol. 193(4):1213-9, 2015 Apr NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Feasibility Studies MH - *Head-Down Tilt/ph [Physiology] MH - Humans MH - *Intraocular Pressure/ph [Physiology] MH - *Laparoscopy MH - Male MH - Middle Aged MH - Patient Positioning/mt [Methods] MH - *Patient Positioning MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Robotic Surgical Procedures KW - head-down tilt; intraocular pressure; prostate; prostatectomy; robotics AB - PURPOSE: The Trendelenburg position has a dramatic effect on circulation, consequently increasing cerebral and intraocular pressure. We evaluated whether modifying the Trendelenburg position would minimize the increase in intraocular pressure. AB - MATERIALS AND METHODS: In this prospective, randomized, controlled study we compared intraocular pressure in patients undergoing robot-assisted laparoscopic radical prostatectomy while in the Trendelenburg position or the modified Z Trendelenburg position. In group 1 intraocular pressure, blood pressure and endotracheal CO2 were measured in the patient at anesthesia induction (time 1), before positioning (time 2), and while in the Trendelenburg position (time 3) and in the modified Z Trendelenburg position (time 4). They were also measured after pneumoperitoneum (time 5), every 30 minutes (times 6 to 16), while supine at the end of pneumoperitoneum (time 17) and before awakening (time 18). We modified the Trendelenburg position by placing the head and shoulders horizontally. AB - RESULTS: Group 1 included 29 patients in the modified Z Trendelenburg position. Group 2 included 21 patients in the Trendelenburg position. No difference was found in patient demographics or surgical outcomes. Median intraocular pressure was in the low normal range at times 1 and 2, and increased in time 3 in each group. From time 4 intraocular pressure decreased and at all time points it was significantly lower in group 1 by a mean of 4.61 mm Hg (95% CI -6.90-2.30, p <0.001). At time 17 mean intraocular pressure decreased to normal (19.6 mm Hg) in group 1 but remained in the hypertensive range (24.9 mm Hg) in group 2. At time 18 mean intraocular pressure was 17 mm Hg in each group. Blood pressure was significantly lower in group 1 with a mean reduction in systolic and diastolic pressure of 6.3 and 4.3 mm Hg, respectively. AB - CONCLUSIONS: Our results suggest that modifying the Trendelenburg position during robot-assisted laparoscopic radical prostatectomy has a significant positive effect on patient neuro-ocular safety by lowering intraocular pressure and accelerating its recovery to the normal range without affecting the operation. AB - Copyright © 2015 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(14)04794-6 DO - https://dx.doi.org/10.1016/j.juro.2014.10.094 PT - Journal Article PT - Randomized Controlled Trial ID - 25444990 [pubmed] ID - S0022-5347(14)04794-6 [pii] ID - 10.1016/j.juro.2014.10.094 [doi] PP - ppublish PH - 2014/10/15 [accepted] LG - English EP - 20141023 DP - 2015 Apr DC - 20150420 EZ - 2014/12/03 06:00 DA - 2015/06/26 06:00 DT - 2014/12/03 06:00 YR - 2015 ED - 20150625 RD - 20150420 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25444990 <183. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25281778 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bianco FJ AU - Albala DM AU - Belkoff LH AU - Miles BJ AU - Peabody JO AU - He W AU - Bradt JS AU - Haas GP AU - Ahlering TE FA - Bianco, Fernando J FA - Albala, David M FA - Belkoff, Laurence H FA - Miles, Brian J FA - Peabody, James O FA - He, Weizhong FA - Bradt, Jason S FA - Haas, Gabriel P FA - Ahlering, Thomas E IN - Bianco, Fernando J. Urological Research Network, Miami, Florida. IN - Albala, David M. Associated Medical Professionals, Syracuse, New York. IN - Belkoff, Laurence H. Urologic Consultants of Southeastern Pennsylvania, Bala Cynwyd, Pennsylvania. IN - Miles, Brian J. Houston Methodist Research Institute, Houston, Texas. IN - Peabody, James O. Vattikuti Urology Institute, Henry Ford Hospital, Detroit, Michigan. IN - He, Weizhong. Astellas, Northbrook, Illinois. IN - Bradt, Jason S. Astellas, Northbrook, Illinois. IN - Haas, Gabriel P. Astellas, Northbrook, Illinois. IN - Ahlering, Thomas E. UC Irvine, Orange, California. TI - A randomized, double-blind, solifenacin succinate versus placebo control, phase 4, multicenter study evaluating urinary continence after robotic assisted radical prostatectomy. CM - Comment in: J Urol. 2015 Apr;193(4):1310; PMID: 25615896 SO - Journal of Urology. 193(4):1305-10, 2015 Apr AS - J Urol. 193(4):1305-10, 2015 Apr NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Double-Blind Method MH - Humans MH - Male MH - Middle Aged MH - *Muscarinic Antagonists/tu [Therapeutic Use] MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - *Quinuclidines/tu [Therapeutic Use] MH - *Robotic Surgical Procedures MH - Solifenacin Succinate MH - *Tetrahydroisoquinolines/tu [Therapeutic Use] MH - *Urinary Incontinence/dt [Drug Therapy] MH - Urinary Incontinence/et [Etiology] KW - prostatectomy; prostatic neoplasms; robotics; treatment outcome; urinary incontinence AB - PURPOSE: Bladder dysfunction influences recovery of urinary continence after radical prostatectomy. We performed a multicenter, randomized, double-blind study evaluating solifenacin vs placebo on return to continence in patients who were still incontinent 7 to 21 days after catheter removal after robot-assisted radical prostatectomy. AB - MATERIALS AND METHODS: A wireless personal digital assistant was given to patients the day of catheter removal. Encrypted answers were transmitted daily to dedicated servers. After a 7 to 21-day treatment-free washout period, patients requiring 2 to 10 pads per day for 7 consecutive days were randomized (1:1) to 5 mg solifenacin daily or placebo. The primary end point was time from first dose to continence defined as 0 pads per day or a dry security pad for 3 consecutive days. Secondary end points included proportion of patients continent at end of study, average change in pads per day number and quality of life assessments. AB - RESULTS: A total of 1,086 screened patients recorded personal digital assistant information. Overall 640 patients were randomized to solifenacin vs placebo and 17 failed to take medication. There was no difference in time to continence (p=0.17). Continence was achieved by study end in 91 of 313 (29%) vs 66 of 309 (21%), respectively (p=0.04). Pads per day change from baseline was -3.2 and -2.9, respectively (p=0.03). Dry mouth was the only common adverse event seen in 6.1% and 0.6%, respectively. Constipation rates were similar. The overall rate of continence in the entire population from screening to end of study was 73%. AB - CONCLUSIONS: There was no effect on primary outcome but some secondary end points benefited the solifenacin arm. The study provides level 1B clinical evidence for continence outcomes after robot-assisted radical prostatectomy. AB - Copyright © 2015 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. RN - 0 (Muscarinic Antagonists) RN - 0 (Quinuclidines) RN - 0 (Tetrahydroisoquinolines) RN - KKA5DLD701 (Solifenacin Succinate) ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(14)04586-8 DO - https://dx.doi.org/10.1016/j.juro.2014.09.106 PT - Clinical Trial, Phase IV PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 25281778 [pubmed] ID - S0022-5347(14)04586-8 [pii] ID - 10.1016/j.juro.2014.09.106 [doi] PP - ppublish PH - 2014/09/24 [accepted] LG - English EP - 20141002 DP - 2015 Apr DC - 20150420 EZ - 2014/10/05 06:00 DA - 2015/06/26 06:00 DT - 2014/10/05 06:00 YR - 2015 ED - 20150625 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25281778 <184. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25277215 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Heemskerk J AU - Zandbergen HR AU - Keet SW AU - Martijnse I AU - van Montfort G AU - Peters RJ AU - Svircevic V AU - Bouwman RA AU - Baeten CG AU - Bouvy ND FA - Heemskerk, Jeroen FA - Zandbergen, H Reinier FA - Keet, Sander W M FA - Martijnse, Ingrid FA - van Montfort, Gust FA - Peters, Rob J A FA - Svircevic, Vesna FA - Bouwman, R Arthur FA - Baeten, Cor G M I FA - Bouvy, Nicole D IN - Heemskerk, Jeroen. Department of General Surgery, Laurentius Hospital Roermond, Roermond, The Netherlands. TI - Relax, it's just laparoscopy! A prospective randomized trial on heart rate variability of the surgeon in robot-assisted versus conventional laparoscopic cholecystectomy. SO - Digestive Surgery. 31(3):225-32, 2014 AS - Dig Surg. 31(3):225-32, 2014 NJ - Digestive surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - c8c, 8501808 IO - Dig Surg SB - Index Medicus CP - Switzerland MH - Adult MH - Analysis of Variance MH - *Cholecystectomy, Laparoscopic/mt [Methods] MH - Cholecystectomy, Laparoscopic/px [Psychology] MH - *Electrocardiography MH - Female MH - *Heart Rate/ph [Physiology] MH - Humans MH - Male MH - Middle Aged MH - Netherlands MH - Occupational Diseases/di [Diagnosis] MH - Prospective Studies MH - *Robotic Surgical Procedures/mt [Methods] MH - Robotic Surgical Procedures/px [Psychology] MH - Statistics, Nonparametric MH - Stress, Psychological MH - *Surgeons/px [Psychology] AB - BACKGROUND: Laparoscopic surgery might be beneficial for the patient, but it imposes increased physical and mental strain on the surgeon. Robot-assisted laparoscopic surgery addresses some of the laparoscopic drawbacks and may potentially reduce mental strain. This could reduce the risk of surgeon's fatigue, mishaps and strain-induced illnesses, which may eventually improve the safety of laparoscopic surgical procedures. AB - METHODS: To test this hypothesis, a randomized study was performed, comparing both heart rate and heart rate variability (HRV) of the surgeon as a measure of total and mental strain, respectively, during conventional and robot-assisted laparoscopic cholecystectomy. AB - RESULTS: Both heart rate and HRV (the low-frequency band/high-frequency band ratio) were significantly decreased when using robotic assistance. AB - CONCLUSIONS: These data suggest the use of the daVinci Surgical System leads to less physical and mental strain of the surgeon during surgery. However, assessing mental strain by means of HRV is cumbersome since there is no clear cutoff point or scale for maximum tolerated strain levels and its related effects on surgeon's health. ES - 1421-9883 IL - 0253-4886 DI - 000365580 DO - https://dx.doi.org/10.1159/000365580 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 25277215 [pubmed] ID - 000365580 [pii] ID - 10.1159/000365580 [doi] PP - ppublish PH - 2014/01/13 [received] PH - 2014/06/29 [accepted] LG - English EP - 20140925 DP - 2014 DC - 20141017 EZ - 2014/10/04 06:00 DA - 2015/06/26 06:00 DT - 2014/10/04 06:00 YR - 2014 ED - 20150625 RD - 20141017 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25277215 <185. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24946742 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bric J AU - Connolly M AU - Kastenmeier A AU - Goldblatt M AU - Gould JC FA - Bric, Justin FA - Connolly, Michael FA - Kastenmeier, Andrew FA - Goldblatt, Matthew FA - Gould, Jon C IN - Bric, Justin. Division of General Surgery, Department of Surgery, Medical College of Wisconsin, 9200 W Wisconsin Avenue, Milwaukee, WI, 53226, USA. TI - Proficiency training on a virtual reality robotic surgical skills curriculum. SO - Surgical Endoscopy. 28(12):3343-8, 2014 Dec AS - Surg Endosc. 28(12):3343-8, 2014 Dec NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Clinical Competence MH - *Computer Simulation MH - *Curriculum MH - *Education, Medical, Undergraduate/mt [Methods] MH - Humans MH - Laparoscopy/ed [Education] MH - *Models, Educational MH - *Robotics/ed [Education] MH - Students, Medical MH - Task Performance and Analysis MH - United States MH - *User-Computer Interface AB - INTRODUCTION: The clinical application of robotic surgery is increasing. The skills necessary to perform robotic surgery are unique from those required in open and laparoscopic surgery. A validated laparoscopic surgical skills curriculum (Fundamentals of Laparoscopic Surgery or FLSTM) has transformed the way surgeons acquire laparoscopic skills. There is a need for a similar skills training and assessment tool for robotic surgery. Our research group previously developed and validated a robotic training curriculum in a virtual reality (VR) simulator. We hypothesized that novice robotic surgeons could achieve proficiency levels defined by more experienced robotic surgeons on the VR robotic curriculum, and that this would result in improved performance on the actual daVinci Surgical SystemTM. AB - METHODS: 25 medical students with no prior robotic surgery experience were recruited. Prior to VR training, subjects performed 2 FLS tasks 3 times each (Peg Transfer, Intracorporeal Knot Tying) using the daVinci Surgical SystemTM docked to a video trainer box. Task performance for the FLS tasks was scored objectively. Subjects then practiced on the VR simulator (daVinci Skills Simulator) until proficiency levels on all 5 tasks were achieved before completing a post-training assessment of the 2 FLS tasks on the daVinci Surgical SystemTM in the video trainer box. AB - RESULTS: All subjects to complete the study (1 dropped out) reached proficiency levels on all VR tasks in an average of 71 (+/- 21.7) attempts, accumulating 164.3 (+/- 55.7) minutes of console training time. There was a significant improvement in performance on the robotic FLS tasks following completion of the VR training curriculum. AB - CONCLUSIONS: Novice robotic surgeons are able to attain proficiency levels on a VR simulator. This leads to improved performance in the daVinci surgical platform on simulated tasks. Training to proficiency on a VR robotic surgery simulator is an efficient and viable method for acquiring robotic surgical skills. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-014-3624-5 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 24946742 [pubmed] ID - 10.1007/s00464-014-3624-5 [doi] PP - ppublish PH - 2014/02/07 [received] PH - 2014/05/16 [accepted] LG - English EP - 20140620 DP - 2014 Dec DC - 20141111 EZ - 2014/06/21 06:00 DA - 2015/06/24 06:00 DT - 2014/06/21 06:00 YR - 2014 ED - 20150622 RD - 20141111 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24946742 <186. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24928233 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Zihni AM AU - Ohu I AU - Cavallo JA AU - Cho S AU - Awad MM FA - Zihni, Ahmed M FA - Ohu, Ikechukwu FA - Cavallo, Jaime A FA - Cho, Sohyung FA - Awad, Michael M IN - Zihni, Ahmed M. Department of Surgery, Section of Minimally Invasive Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8109, St. Louis, MO, 63110, USA, zihnia@wudosis.wustl.edu. TI - Ergonomic analysis of robot-assisted and traditional laparoscopic procedures. SO - Surgical Endoscopy. 28(12):3379-84, 2014 Dec AS - Surg Endosc. 28(12):3379-84, 2014 Dec NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - *Arm/ph [Physiology] MH - Electromyography MH - *Human Engineering MH - Humans MH - *Laparoscopy MH - *Muscle, Skeletal/ph [Physiology] MH - *Robotics AB - INTRODUCTION: Many laparoscopic surgeons report musculoskeletal symptoms that are thought to be related to the ergonomic stress of performing laparoscopy. Robotic surgical systems may address many of these limitations. To date, however, there have been no studies exploring the quantitative ergonomics of robotic surgery. In this study, we sought to compare the activation of bilateral biceps, triceps, deltoid, and trapezius muscle groups during traditional laparoscopic surgery (TLS) and robot-assisted laparoscopic surgery (RALS) procedures, as quantified by surface electromyography (sEMG). AB - METHODS: One surgeon with expertise in TLS and RALS performed 18 operative procedures (13 TLS, 5 RALS) while sEMG measurements were obtained from bilateral biceps, triceps, deltoid, and trapezius muscles. sEMG measurements were normalized to the maximum voluntary contraction of each muscle (%MVC). We compared mean %MVC values for each muscle group during TLS and RALS with unpaired t-tests and considered differences with a p value <0.05 to be statistically significant. AB - RESULTS: Muscle activation was higher during TLS compared to RALS in bilateral biceps (L Biceps RALS:1.01%MVC, L Biceps TLS:3.14, p = 0.01; R Biceps RALS:1.81%MVC, R Biceps TLS:4.53, p = 0.0002). Muscle activation was higher during TLS compared to RALS in bilateral triceps (L Triceps RALS:1.73%MVC, L Triceps TLS:3.58, p = 0.04; R Triceps RALS:1.59%MVC, R Triceps TLS:5.11, p = 0.02). Muscle activation was higher during TLS compared to RALS in bilateral deltoids (L Deltoid RALS:1.50%MVC, L Deltoid TLS:3.68, p = 0.03; R Deltoid RALS:1.19%MVC, R Deltoid TLS:2.57, p = 0.01). Significant differences were not detected in the bilateral trapezius muscles (L Trapezius RALS:1.50 %MVC, L Trapezius TLS:3.68, p = 0.03; R Trapezius RALS:1.19%MVC, R Trapezius TLS:2.57, p = 0.01). AB - DISCUSSION: We have quantitatively examined the ergonomics of TLS and RALS and shown that in a single surgeon, TLS procedures are associated with significantly elevated biceps, triceps, and deltoid activation bilaterally when compared to RALS procedures. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-014-3604-9 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 24928233 [pubmed] ID - 10.1007/s00464-014-3604-9 [doi] PP - ppublish PH - 2014/03/02 [received] PH - 2014/04/30 [accepted] LG - English EP - 20140614 DP - 2014 Dec DC - 20141111 EZ - 2014/06/15 06:00 DA - 2015/06/24 06:00 DT - 2014/06/15 06:00 YR - 2014 ED - 20150622 RD - 20141111 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24928233 <187. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25218465 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Gu X AU - Araki M AU - Wong C FA - Gu, Xiao FA - Araki, Motoo FA - Wong, Carson IN - Gu, Xiao. Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA; Department of Urology, Clinical Medical College at Yangzhou University, Yangzhou, Jiangsu 225001, China. Electronic address: guxiao222@hotmail.com. IN - Araki, Motoo. Department of Urology, Okayama University Graduate School of Medicine, Shikata-cho Okayama-shi, Okayama 700-8558, Japan. Electronic address: motoosh2@gmail.com. IN - Wong, Carson. SouthWest Urology, LLC, Middleburg Heights, OH 44130, USA. Electronic address: carsonwong09@gmail.com. TI - Does elevated body mass index (BMI) affect the clinical outcomes of robot-assisted laparoscopic prostatectomy (RALP): a prospective cohort study. SO - International Journal Of Surgery. 12(10):1055-60, 2014 Oct AS - Int J Surg. 12(10):1055-60, 2014 Oct NJ - International journal of surgery (London, England) PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101228232 IO - Int J Surg SB - Index Medicus CP - England MH - Aged MH - *Body Mass Index MH - Humans MH - *Laparoscopy MH - Male MH - Middle Aged MH - Obesity/co [Complications] MH - Operative Time MH - Overweight/co [Complications] MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotic Surgical Procedures KW - Body mass index; Clinical outcomes; Laparoscopy; Radical prostatectomy; Robot-assisted AB - OBJECTIVES: With the prevalence of obesity in the United States, a significant proportion of robot-assisted laparoscopic prostatectomy (RALP) candidates have an elevated body mass index (BMI). We determine if this impacts on the clinical outcomes of RALP. AB - METHODS: 218 consecutive patients underwent RALP were identified from a prospectively maintained RALP database recorded and compared for their demographics, clinical outcomes and adverse events in normal weight (BMI <25 kg/m(2)), overweight (BMI >25 and <30 kg/m(2)) and obese (BMI >30 kg/m(2)) groups. AB - RESULTS: 36 normal weight, 115 overweight and 67 obese patients were identified. There were no significant differences in demographic data among the three groups except for mean BMI (23.1 vs. 27.5 vs. 32.8 kg/m(2), p < 0.001). The median operative time was longer in obese patients compared to both overweight (210 vs. 189 min, p = 0.031) and normal weight (210 vs. 177 min, p = 0.008) patients. There were no significant differences in median estimated blood loss, mean prostate volume, positive surgical margin rate and time to continence without pads. The median urethral catheter duration and hospitalization were similar in all groups. Patients with elevated BMI had a significantly higher median Gleason score (p = 0.046) and incidence of pathologic T3 disease (p = 0.038). The incidence of adverse events was low and there were no significant differences among the three groups (p > 0.05). AB - CONCLUSIONS: Elevated BMI appears to increase the RALP operative time, but has little impact on other intraoperative parameters, clinical outcomes or patient morbidity. RALP is a safe and effective procedure in patients with elevated BMI. AB - Copyright © 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved. ES - 1743-9159 IL - 1743-9159 DI - S1743-9191(14)00893-0 DO - https://dx.doi.org/10.1016/j.ijsu.2014.08.408 PT - Journal Article ID - 25218465 [pubmed] ID - S1743-9191(14)00893-0 [pii] ID - 10.1016/j.ijsu.2014.08.408 [doi] PP - ppublish PH - 2014/06/18 [received] PH - 2014/08/12 [revised] PH - 2014/08/31 [accepted] LG - English EP - 20140912 DP - 2014 Oct DC - 20141011 EZ - 2014/09/15 06:00 DA - 2015/06/16 06:00 DT - 2014/09/15 06:00 YR - 2014 ED - 20150615 RD - 20141011 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25218465 <188. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25218366 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ayloo S AU - Roh Y AU - Choudhury N FA - Ayloo, Subhashini FA - Roh, Younghoon FA - Choudhury, Nabajit IN - Ayloo, Subhashini. Division of General, Minimally Invasive and Robotic Surgery, Department of Surgery, University of Illinois Hospital and Health Sciences, Chicago, IL, USA. Electronic address: drsayloo@gmail.com. IN - Roh, Younghoon. Department of Surgery, Dong-A University Hospital, Busan 602-715, South Korea. IN - Choudhury, Nabajit. Division of General, Minimally Invasive and Robotic Surgery, Department of Surgery, University of Illinois Hospital and Health Sciences, Chicago, IL, USA. TI - Laparoscopic versus robot-assisted cholecystectomy: a retrospective cohort study. SO - International Journal Of Surgery. 12(10):1077-81, 2014 Oct AS - Int J Surg. 12(10):1077-81, 2014 Oct NJ - International journal of surgery (London, England) PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101228232 IO - Int J Surg SB - Index Medicus CP - England MH - Adult MH - *Cholecystectomy MH - *Cholecystectomy, Laparoscopic MH - Cohort Studies MH - Conversion to Open Surgery/sn [Statistics & Numerical Data] MH - Female MH - Humans MH - Length of Stay/sn [Statistics & Numerical Data] MH - Male MH - Operative Time MH - Postoperative Complications MH - Retrospective Studies MH - *Robotic Surgical Procedures KW - Case series; Cholecystectomy; Laparoscopy; Outcomes; Robot-assisted surgery; Safety AB - INTRODUCTION: Robot-assisted surgery has permeated all surgical specialties including general surgery. Still, only a few small experimental series have compared experiences between laparoscopic cholecystectomy (LC) and robotic cholecystectomy (RC). We present a single surgeon's experience with LC versus RC in a large case series. AB - METHODS: We conducted an IRB-approved retrospective review of 326 patients (147 LC and 179 RC) who underwent surgery between September 2005 and June 2012. The same selection criteria and standardized surgical technique was used for all patients. Demographics collected included patient age, gender, body mass index (BMI), operating time, estimated blood loss (EBL), associated procedures, conversions, intraoperative and postoperative complications, and hospital length of stay (LOS). AB - RESULTS: The LC group (26 males/121 females) had a mean age, BMI, operative time, and EBL of 41.1 years, 31.8 kg/m(2), 89.60 min, and 13.7 ml, respectively. Three cases were converted to open surgery and there were three major complications. The mean LOS was 1.01 days. The RC group (30 males/149 females) had a mean age, BMI, operative time, and EBL of 40.2 years, 32.9 kg/m(2), 95.7 min, and 13.9 ml, respectively. Two cases were converted to open surgery and there were three major complications. The mean LOS was 0.9 days. AB - CONCLUSIONS: LC and RC are comparable in terms of feasibility, safety, and reproducibility of outcomes in all cholecystectomy settings. Robotic assistance may be useful in managing biliary injuries during the LC procedure. AB - Copyright © 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved. ES - 1743-9159 IL - 1743-9159 DI - S1743-9191(14)00890-5 DO - https://dx.doi.org/10.1016/j.ijsu.2014.08.405 PT - Comparative Study PT - Journal Article ID - 25218366 [pubmed] ID - S1743-9191(14)00890-5 [pii] ID - 10.1016/j.ijsu.2014.08.405 [doi] PP - ppublish PH - 2014/06/15 [received] PH - 2014/08/16 [revised] PH - 2014/08/20 [accepted] LG - English EP - 20140909 DP - 2014 Oct DC - 20141011 EZ - 2014/09/15 06:00 DA - 2015/06/16 06:00 DT - 2014/09/15 06:00 YR - 2014 ED - 20150615 RD - 20141011 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25218366 <189. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24699301 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Wechter ME AU - Mohd J AU - Magrina JF AU - Cornella JL AU - Magtibay PM AU - Wilson JR AU - Kho RM FA - Wechter, Mary Ellen FA - Mohd, Jasmine FA - Magrina, Javier F FA - Cornella, Jeffrey L FA - Magtibay, Paul M FA - Wilson, Jeffrey R FA - Kho, Rosanne M IN - Wechter, Mary Ellen. Department of Obstetrics and Gynecology, North Florida OBGYN, Division 1, Baptist Medical Center, Jacksonville, Florida. Electronic address: mwechter@nfobgyn.com. IN - Mohd, Jasmine. Department of Minimally Invasive Surgery, KK Women's and Children's Hospital, Singapore. IN - Magrina, Javier F. Department of Gynecologic Surgery, Mayo Clinic Arizona, Phoenix. IN - Cornella, Jeffrey L. Department of Gynecologic Surgery, Mayo Clinic Arizona, Phoenix. IN - Magtibay, Paul M. Department of Gynecologic Surgery, Mayo Clinic Arizona, Phoenix. IN - Wilson, Jeffrey R. Department of Biostatistics, Arizona State University, Phoenix. IN - Kho, Rosanne M. Department of Gynecologic Surgery, Mayo Clinic Arizona, Phoenix. TI - Complications in robotic-assisted gynecologic surgery according to case type: a 6-year retrospective cohort study using Clavien-Dindo classification. SO - Journal of Minimally Invasive Gynecology. 21(5):844-50, 2014 Sep-Oct AS - J Minim Invasive Gynecol. 21(5):844-50, 2014 Sep-Oct NJ - Journal of minimally invasive gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101235322 IO - J Minim Invasive Gynecol SB - Index Medicus CP - United States MH - Aged MH - Blood Loss, Surgical MH - Body Mass Index MH - Cohort Studies MH - *Cystectomy MH - *Endometriosis/su [Surgery] MH - Female MH - Humans MH - *Hysterectomy MH - *Intraoperative Complications/ep [Epidemiology] MH - Intraoperative Complications/et [Etiology] MH - Laparoscopy/mt [Methods] MH - *Laparoscopy MH - Length of Stay MH - Middle Aged MH - Operative Time MH - *Postoperative Complications/ep [Epidemiology] MH - Postoperative Complications/et [Etiology] MH - Retrospective Studies MH - Risk Assessment MH - *Robotics MH - *Uterine Myomectomy KW - Complications; Gynecologic surgery; Gynecology; Postoperative; Robotics AB - STUDY OBJECTIVE: To estimate the risk of postoperative complications in robotic-assisted gynecologic surgery according to case type. AB - STUDY DESIGN: Retrospective cohort study (Canadian Task Force classification II-2). AB - SETTING: Mayo Clinic Arizona. AB - PATIENTS: All 1155 patients who underwent robotic-assisted gynecologic surgery between March 2004 and December 2009 were included. Patients were primarily white (94.3%), with a mean (SD) age of 51.5 (15.4) years, and were overweight, with body mass index (BMI) of 27.2 (6.8). AB - INTERVENTIONS: Risk of complications, overall and according to Clavien-Dindo grade, and incidence of specific complications were analyzed. Robotic-assisted gynecologic surgical procedures were categorized postoperatively according to case type as benign simple (e.g., oophorectomy, simple hysterectomy) in 552 (47.8%) patients, benign complex (e.g., excision of invasive endometriosis) in 262 (22.7%), urogynecologic in 121 (10.5%), and oncologic in 220 (19.1%). AB - MEASUREMENTS AND MAIN RESULTS: Intraoperative complications occurred in 3.2% of patients. Postoperative complications of any type occurred in 18.4% of patients. Conversion to laparotomy was necessary in 2.7%. Urologic complications were more common in urogynecologic cases (5.8%) as compared with benign simple (0.5%), benign complex (2.7%), and oncologic (3.2%). Bleeding complications were most common in oncologic cases (5%). Clavien-Dindo grade > 3 complications occurred in 5.2% of patients overall, and were >3-fold likely to occur in benign complex, urogynecologic, and oncologic cases than in benign simple cases. When adjusted for age, BMI, estimated blood loss, operative time, length of stay, and previous pelvic surgery, complications were nearly twice as common for benign complex (odds ratio [OR] 1.7; 95% confidence interval [CI], 1.1-2.7), urogynecologic (OR 1.9; 95% CI, 1.0-3.4), and oncologic (OR 1.9; 95% CI, 1.1-3.1) cases as for benign simple cases, although weakly significant. Case type, BMI, estimated blood loss, and length of stay remained important factors in predicting postoperative complications. AB - CONCLUSION: The incidence of complications in robotic-assisted gynecologic surgery varies according to case type. Defining the role of patient and surgical variables such as case type in the occurrence of complications may help in identification of cases with increased risk, to improve patient counseling and surgical outcome. AB - Copyright © 2014 AAGL. Published by Elsevier Inc. All rights reserved. ES - 1553-4669 IL - 1553-4650 DI - S1553-4650(14)00211-8 DO - https://dx.doi.org/10.1016/j.jmig.2014.03.016 PT - Journal Article ID - 24699301 [pubmed] ID - S1553-4650(14)00211-8 [pii] ID - 10.1016/j.jmig.2014.03.016 [doi] PP - ppublish PH - 2014/02/06 [received] PH - 2014/03/15 [revised] PH - 2014/03/18 [accepted] LG - English EP - 20140331 DP - 2014 Sep-Oct DC - 20140909 EZ - 2014/04/05 06:00 DA - 2015/06/16 06:00 DT - 2014/04/05 06:00 YR - 2014 ED - 20150615 RD - 20140909 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24699301 <190. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25462201 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hotujec BT AU - Spencer RJ AU - Donnelly MJ AU - Bruggink SM AU - Rose SL AU - Al-Niaimi A AU - Chappell R AU - Stewart SL AU - Kushner DM FA - Hotujec, B T FA - Spencer, R J FA - Donnelly, M J FA - Bruggink, S M FA - Rose, S L FA - Al-Niaimi, A FA - Chappell, R FA - Stewart, S L FA - Kushner, D M IN - Hotujec, B T. Department of Obstetrics and Gynecology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA. IN - Spencer, R J. Division of Gynecologic Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA. IN - Donnelly, M J. Department of Anesthesiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA. IN - Bruggink, S M. Department of Anesthesiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA. IN - Rose, S L. Division of Gynecologic Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA. IN - Al-Niaimi, A. Division of Gynecologic Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA. IN - Chappell, R. Department of Biostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA. IN - Stewart, S L. Division of Gynecologic Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA. IN - Kushner, D M. Division of Gynecologic Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA. Electronic address: dmkushner@wisc.edu. TI - Transversus abdominis plane block in robotic gynecologic oncology: a randomized, placebo-controlled trial. SO - Gynecologic Oncology. 136(3):460-5, 2015 Mar AS - Gynecol Oncol. 136(3):460-5, 2015 Mar NJ - Gynecologic oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - fxc, 0365304 IO - Gynecol. Oncol. SB - Index Medicus CP - United States MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Analgesics, Opioid/tu [Therapeutic Use] MH - *Anesthetics, Local/tu [Therapeutic Use] MH - *Bupivacaine/tu [Therapeutic Use] MH - Double-Blind Method MH - Female MH - Follow-Up Studies MH - *Genital Neoplasms, Female/su [Surgery] MH - Humans MH - *Laparoscopy MH - Linear Models MH - Middle Aged MH - Morphine/tu [Therapeutic Use] MH - *Nerve Block/mt [Methods] MH - Nomograms MH - Pain Measurement MH - Pain, Postoperative/dt [Drug Therapy] MH - *Pain, Postoperative/pc [Prevention & Control] MH - *Robotics MH - Treatment Outcome MH - Young Adult KW - Postoperative analgesia; Robotic surgery; Transversus abdominis plane block AB - OBJECTIVE: Although robotic surgery decreases pain compared to laparotomy, postoperative pain can be a concern near the site of a larger assistant trocar site. The aim of this study was to determine the efficacy of transversus abdominis plane (TAP) block on 24-hour postoperative opiate use after robotic surgery for gynecologic cancer. AB - METHODS: Sixty-four subjects with gynecologic malignancies who were scheduled to undergo robotic surgery were enrolled into the study. They were randomized to receive a unilateral TAP block to the side of the assistant port via ultrasound guidance. The block was comprised of 30 cc of 0.25% bupivacaine with 3 mcg/mL epinephrine or saline. Opiate use was measured and converted into IV morphine equivalents. Patient-reported pain was measured using the Brief Pain Inventory (BPI) and Visual Analog Scale (VAS). AB - RESULTS: The treatment group used a mean of 64.9 mg morphine in the first 24h compared to 69.3mg for controls (primary outcome, p=0.52). After age-adjustment, the treatment group used a mean of 11.1mg morphine less than controls (p=0.09). Postoperative pain scores assessed by the BPI (6.44 vs. 6.97, p=0.37) and the VAS (3.12 vs. 3.61, p=0.30) were equivalent. Block placement was uncomplicated in 98.4% of participants with mean BMI of 35.3 kg/m(2). Linear regression revealed an approximate 8.1mg decrease in morphine equivalents used per additional decade of life (p=0.0008). There was a positive correlation between the amount of opiates and BMI with an additional 8.8 mg of morphine per 10 kg/m(2) increase in BMI (p=0.0012). AB - CONCLUSIONS: TAP block is safe and feasible in this patient population with a large proportion of morbid obesity. Preoperative TAP block does not significantly decrease opiate use. However; based on these data, a clinically useful nomogram has been created to aid clinicians in postoperative opiate-dosing for patients based on age and BMI. AB - Copyright © 2014 Elsevier Inc. All rights reserved. RN - 0 (Analgesics, Opioid) RN - 0 (Anesthetics, Local) RN - 76I7G6D29C (Morphine) RN - Y8335394RO (Bupivacaine) ES - 1095-6859 IL - 0090-8258 DI - S0090-8258(14)01477-2 DO - https://dx.doi.org/10.1016/j.ygyno.2014.11.013 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 25462201 [pubmed] ID - S0090-8258(14)01477-2 [pii] ID - 10.1016/j.ygyno.2014.11.013 [doi] PP - ppublish PH - 2014/08/16 [received] PH - 2014/10/13 [revised] PH - 2014/11/03 [accepted] LG - English EP - 20141120 DP - 2015 Mar DC - 20150310 EZ - 2014/12/03 06:00 DA - 2015/06/10 06:00 DT - 2014/12/03 06:00 YR - 2015 ED - 20150609 RD - 20150310 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25462201 <191. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24893325 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Liang MI AU - McCann GA AU - Rath KS AU - Backes FJ AU - Cansino C AU - Salani R FA - Liang, Margaret I FA - McCann, Georgia A FA - Rath, Kellie S FA - Backes, Floor J FA - Cansino, Catherine FA - Salani, Ritu IN - Liang, Margaret I. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The Ohio State University, Columbus, Ohio. IN - McCann, Georgia A. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The Ohio State University, Columbus, Ohio. IN - Rath, Kellie S. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The Ohio State University, Columbus, Ohio. IN - Backes, Floor J. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The Ohio State University, Columbus, Ohio. IN - Cansino, Catherine. Division of General Obstetrics and Gynecology, Department of Obstetrics and Gynecology, The Ohio State University, Columbus, Ohio. IN - Salani, Ritu. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The Ohio State University, Columbus, Ohio. Electronic address: ritu.salani@osumc.edu. TI - Training the next generation of robotic surgeons using guided mentorship: a randomized controlled trial. SO - Journal of Minimally Invasive Gynecology. 21(6):1075-9, 2014 Nov-Dec AS - J Minim Invasive Gynecol. 21(6):1075-9, 2014 Nov-Dec NJ - Journal of minimally invasive gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101235322 IO - J Minim Invasive Gynecol SB - Index Medicus CP - United States MH - Adult MH - Clinical Competence MH - *Education, Medical/mt [Methods] MH - Female MH - Humans MH - Internship and Residency/sn [Statistics & Numerical Data] MH - Male MH - *Mentors MH - Prospective Studies MH - *Robotic Surgical Procedures/ed [Education] MH - Students, Medical/sn [Statistics & Numerical Data] MH - *Surgeons/ed [Education] MH - Young Adult KW - Guided mentorship; Robotic training; Surgical education AB - STUDY OBJECTIVE: To evaluate the effect of expert guided mentorship on technical score and time for a set of robotic training drills. AB - DESIGN: Prospective randomized controlled trial (Canadian Task Force classification I). AB - SETTING: Academic institution. AB - SUBJECTS: Fifty trainees in robotic surgery. AB - INTERVENTION: Inexperienced trainees underwent either a 20-minute expert guided mentorship session or no intervention. The primary outcomes were technical score and time-to-drill completion for a set of dry lab robotic training drills evaluated at an initial and final skills assessment. The t-test, including paired analyses, was used to evaluate outcomes. AB - MEASUREMENTS AND MAIN RESULTS: Forty-nine of 50 trainees (98%) completed the study. There were no significant differences in participant characteristics or initial performance between the 2 groups. During the final skills assessment, the intervention group demonstrated significantly better performance on 1 of 8 objective measures. They had a higher mean score for the bead transfer drill when compared with the control group (21.6 vs 19.9; p = .03). No differences in time-to-drill completion were noted between the 2 groups. Regardless of randomization, all participants had significantly improved scores for each of the drills on the final compared with the initial skills assessment (p < .01). AB - CONCLUSIONS: Although expert guided mentorship in a dry lab simulation environment seems feasible, further investigation is warranted before its widespread use because it may be more resource intensive than other teaching methods, without consistent objective improvements in technical performance. AB - Copyright © 2014 AAGL. Published by Elsevier Inc. All rights reserved. ES - 1553-4669 IL - 1553-4650 DI - S1553-4650(14)00297-0 DO - https://dx.doi.org/10.1016/j.jmig.2014.05.011 PT - Journal Article PT - Randomized Controlled Trial ID - 24893325 [pubmed] ID - S1553-4650(14)00297-0 [pii] ID - 10.1016/j.jmig.2014.05.011 [doi] PP - ppublish PH - 2014/03/27 [received] PH - 2014/05/21 [revised] PH - 2014/05/27 [accepted] LG - English EP - 20140602 DP - 2014 Nov-Dec DC - 20141202 EZ - 2014/06/04 06:00 DA - 2015/06/05 06:00 DT - 2014/06/04 06:00 YR - 2014 ED - 20150604 RD - 20141202 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24893325 <192. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25463760 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Chiou HY AU - Chiu LH AU - Chen CH AU - Yen YK AU - Chang CW AU - Liu WM FA - Chiou, Hung-Yi FA - Chiu, Li-Hsuan FA - Chen, Ching-Hui FA - Yen, Yuan-Kuei FA - Chang, Ching-Wen FA - Liu, Wei-Min IN - Chiou, Hung-Yi. School of Public Health, Taipei Medical University, Taipei, Taiwan. IN - Chiu, Li-Hsuan. Department of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei, Taiwan. IN - Chen, Ching-Hui. Department of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. IN - Yen, Yuan-Kuei. Department of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. IN - Chang, Ching-Wen. Department of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. IN - Liu, Wei-Min. Department of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address: weimin@tmu.edu.tw. TI - Comparing robotic surgery with laparoscopy and laparotomy for endometrial cancer management: a cohort study. SO - International Journal Of Surgery. 13:17-22, 2015 Jan AS - Int J Surg. 13:17-22, 2015 Jan NJ - International journal of surgery (London, England) PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101228232 IO - Int J Surg SB - Index Medicus CP - England MH - Adult MH - Aged MH - Blood Loss, Surgical/sn [Statistics & Numerical Data] MH - Disease-Free Survival MH - Endometrial Neoplasms/mo [Mortality] MH - *Endometrial Neoplasms/su [Surgery] MH - Female MH - Humans MH - *Laparoscopy MH - Laparotomy MH - Middle Aged MH - Pain, Postoperative/ep [Epidemiology] MH - Retrospective Studies MH - Robotics/mt [Methods] MH - *Robotics MH - Treatment Outcome KW - Endometrial cancer; Robotic surgery; Surgical staging AB - INTRODUCTION: Robotic surgery has been applied in managing various types of gynecologic cancers. The purpose of this study is to compare the surgical outcomes of robotic surgery, laparoscopy and laparotomy for managing endometrial cancer. AB - METHODS: A total of 365 patients received surgical staging for treating IA to IIIC endometrial cancer were retrospectively enrolled. Patient demography, peri-operative parameters, and survival outcomes were studied. AB - RESULTS AND DISCUSSIONS: Robotic surgery showed a significant lower blood loss and 24-h pain score as compared to other surgical types. Moreover, compared to laparotomy, robotic and laparoscopic surgeries were associated with reduced operation time, decreased time to full diet resumption, and shortened hospital stay. No significant differences were found between the groups in terms of overall complication rate. Eighteen-month follow-up of the patients indicated no significant differences in disease-free survival and overall survival. AB - CONCLUSION: Compared to conventional approaches, robotic surgery showed favorable short-term outcomes with comparable survival. It is suggested that robotic surgery is a feasible tool for endometrial cancer management. AB - Copyright © 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved. ES - 1743-9159 IL - 1743-9159 DI - S1743-9191(14)00975-3 DO - https://dx.doi.org/10.1016/j.ijsu.2014.11.015 PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 25463760 [pubmed] ID - S1743-9191(14)00975-3 [pii] ID - 10.1016/j.ijsu.2014.11.015 [doi] PP - ppublish PH - 2014/09/22 [received] PH - 2014/11/08 [revised] PH - 2014/11/17 [accepted] LG - English EP - 20141118 DP - 2015 Jan DC - 20150209 EZ - 2014/12/03 06:00 DA - 2015/06/04 06:00 DT - 2014/12/03 06:00 YR - 2015 ED - 20150603 RD - 20150209 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25463760 <193. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24887970 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Carter SC AU - Chiang A AU - Shah G AU - Kwan L AU - Montgomery JS AU - Karam A AU - Tarnay C AU - Guru KA AU - Hu JC FA - Carter, Stacey C FA - Chiang, Alexander FA - Shah, Galaxy FA - Kwan, Lorna FA - Montgomery, Jeffrey S FA - Karam, Amer FA - Tarnay, Christopher FA - Guru, Khurshid A FA - Hu, Jim C IN - Carter, Stacey C. *Department of Urology, UCLA, Los Angeles, CA; +Department of Obstetrics and Gynecology, UCLA, Los Angeles, CA ++Department of Urology, University of Michigan, Ann Arbor, MI Department of Obstetrics and Gynecology, Stanford, Palo Alto, CA ||Roswell Park Cancer Institute, Buffalo, NY. TI - Video-based peer feedback through social networking for robotic surgery simulation: a multicenter randomized controlled trial. SO - Annals of Surgery. 261(5):870-5, 2015 May AS - Ann Surg. 261(5):870-5, 2015 May NJ - Annals of surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 67s, 0372354 IO - Ann. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Clinical Competence MH - *Computer Simulation MH - *Feedback MH - *General Surgery/ed [Education] MH - Humans MH - Internship and Residency MH - Learning Curve MH - *Peer Group MH - *Robotics MH - *Social Networking MH - *Video Recording AB - OBJECTIVE: To examine the feasibility and outcomes of video-based peer feedback through social networking to facilitate robotic surgical skill acquisition. AB - BACKGROUND: The acquisition of surgical skills may be challenging for novel techniques and/or those with prolonged learning curves. AB - METHODS: Randomized controlled trial involving 41 resident physicians performing the Tubes (Da Vinci Intuitive Surgical, Sunnyvale, CA) simulator exercise with versus without peer feedback of video-recorded performance through a social networking Web page. Data collected included simulator exercise score, time to completion, and comfort and satisfaction with robotic surgery simulation. AB - RESULTS: There were no baseline differences between the intervention group (n = 20) and controls (n = 21). The intervention group showed improvement in mean scores from session 1 to sessions 2 and 3 (60.7 vs 75.5, P < 0.001, and 60.7 vs 80.1, P < 0.001, respectively). The intervention group scored significantly higher than controls at sessions 2 and 3 (75.5 vs 59.6, P = 0.009, and 80.1 vs 65.9, P = 0.019, respectively). The mean time (seconds) to complete the task was shorter for the intervention group than for controls during sessions 2 and 3 (217.4 vs 279.0, P = 0.004, and 201.4 vs 261.9, P = 0.006, respectively). At the study conclusion, feedback subjects were more comfortable with robotic surgery than controls (90% vs 62%, P = 0.021) and expressed greater satisfaction with the learning experience (100% vs 67%, P = 0.014). Of the intervention subjects, 85% found that peer feedback was useful and 100% found it effective. AB - CONCLUSIONS: Video-based peer feedback through social networking appears to be an effective paradigm for surgical education and accelerates the robotic surgery learning curve during simulation. ES - 1528-1140 IL - 0003-4932 DO - https://dx.doi.org/10.1097/SLA.0000000000000756 PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial ID - 24887970 [pubmed] ID - 10.1097/SLA.0000000000000756 [doi] PP - ppublish LG - English DP - 2015 May DC - 20150404 EZ - 2014/06/03 06:00 DA - 2015/06/02 06:00 DT - 2014/06/03 06:00 YR - 2015 ED - 20150601 RD - 20150404 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24887970 <194. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24161886 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Gorostidi M AU - Larreategui J AU - Bernal T AU - Goiri C AU - Arrue M AU - Navarrina P AU - Lekuona A FA - Gorostidi, Mikel FA - Larreategui, Joana FA - Bernal, Teresa FA - Goiri, Constance FA - Arrue, Miren FA - Navarrina, Pepe FA - Lekuona, Arantxa IN - Gorostidi, Mikel. Department of Obstetrics and Gynecology, Hospital Donostia, Sebastian, Spain. Electronic address: mgorostidi@sego.es. IN - Larreategui, Joana. Department of Obstetrics and Gynecology, Hospital Donostia, Sebastian, Spain. IN - Bernal, Teresa. Department of Obstetrics and Gynecology, Hospital Donostia, Sebastian, Spain. IN - Goiri, Constance. Department of Obstetrics and Gynecology, Hospital Donostia, Sebastian, Spain. IN - Arrue, Miren. Department of Obstetrics and Gynecology, Hospital Donostia, Sebastian, Spain. IN - Navarrina, Pepe. Department of Obstetrics and Gynecology, Hospital Donostia, Sebastian, Spain. IN - Lekuona, Arantxa. Department of Obstetrics and Gynecology, Hospital Donostia, Sebastian, Spain. TI - Robotic retroperitoneal paraaortic lymphadenectomy at Donostia University Hospital. SO - Journal of Minimally Invasive Gynecology. 21(3):480-5, 2014 May-Jun AS - J Minim Invasive Gynecol. 21(3):480-5, 2014 May-Jun NJ - Journal of minimally invasive gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101235322 IO - J Minim Invasive Gynecol SB - Index Medicus CP - United States MH - Adenocarcinoma/su [Surgery] MH - Adult MH - Aged MH - Body Mass Index MH - Endometrial Neoplasms/su [Surgery] MH - Female MH - Hospitals, University MH - Humans MH - *Lymph Node Excision/mt [Methods] MH - Middle Aged MH - Operative Time MH - *Retroperitoneal Space/su [Surgery] MH - Robotics KW - Cervical Cancer; Endometrial Adenocarcinoma; Lymphadenectomy; Retroperitoneal Access; Robotic Surgery AB - The purpose of this study was to describe our robotic retroperitoneal para-aortic lymphadenectomy technique and its associated outcomes as well as the advantages and disadvantages. We prospectively collected data on all retroperitoneal aortocaval lymphadenectomy procedures performed at Donostia University Hospital from December 2011 to April 2013 using the da Vinci S robotic system (Intuitive Surgical, Sunnyvale,CA). A total of 13 of these procedures were performed. The mean patient age was 60.3 years (SD, 10.18). Most patients were obese with a mean body mass index of 31.95 kg/m(2) (SD, 5), and 9 had endometrial cancer. Five individuals were restaged: 4 because of lymphovascular space invasion and 1 because of lymphovascular space invasion with G3 histology. There were 2 cases of Federation Internationale de Gynecologie et d'Obstetrique stage IB endometrial cancer: 1 of papillary serous histology and 1 of G3. Two patients had advanced cervical cancer, and 2 had early-stage ovarian cancer. The median para-aortic lymph node yield was 12 (range, 4-21). In 3 patients, it was necessary to convert the procedure to transperitoneal access because of technical difficulties; 1 of these required laparotomy. The mean surgical time was 323 minutes (SD, 58) although this included additional complex procedures. Robotic para-aortic retroperitoneal lymphadenectomy is feasible and offers the advantages of retroperitoneal access. AB - Copyright © 2014 AAGL. Published by Elsevier Inc. All rights reserved. ES - 1553-4669 IL - 1553-4650 DI - S1553-4650(13)01294-6 DO - https://dx.doi.org/10.1016/j.jmig.2013.10.004 PT - Clinical Trial PT - Journal Article ID - 24161886 [pubmed] ID - S1553-4650(13)01294-6 [pii] ID - 10.1016/j.jmig.2013.10.004 [doi] PP - ppublish PH - 2013/08/21 [received] PH - 2013/10/10 [revised] PH - 2013/10/11 [accepted] LG - English EP - 20131022 DP - 2014 May-Jun DC - 20140505 EZ - 2013/10/29 06:00 DA - 2015/05/30 06:00 DT - 2013/10/29 06:00 YR - 2014 ED - 20150529 RD - 20140505 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24161886 <195. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25819865 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Januzzi JL AU - Sharma U AU - Zakroysky P AU - Truong QA AU - Woodard PK AU - Pope JH AU - Hauser T AU - Mayrhofer T AU - Nagurney JT AU - Schoenfeld D AU - Peacock WF AU - Fleg JL AU - Wiviott S AU - Pang PS AU - Udelson J AU - Hoffmann U FA - Januzzi, James L FA - Sharma, Umesh FA - Zakroysky, Pearl FA - Truong, Quynh A FA - Woodard, Pamela K FA - Pope, J Hector FA - Hauser, Thomas FA - Mayrhofer, Thomas FA - Nagurney, J Toby FA - Schoenfeld, David FA - Peacock, W Frank FA - Fleg, Jerome L FA - Wiviott, Stephen FA - Pang, Peter S FA - Udelson, James FA - Hoffmann, Udo IN - Januzzi, James L. Division of Cardiology, Massachusetts General Hospital, Boston, MA. Electronic address: JJanuzzi@partners.org. IN - Sharma, Umesh. Department of Radiology, Massachusetts General Hospital, Boston, MA. IN - Zakroysky, Pearl. Department of Biostatistics, Massachusetts General Hospital, Boston, MA. IN - Truong, Quynh A. Division of Cardiology, Massachusetts General Hospital, Boston, MA. IN - Woodard, Pamela K. Mallinkrodt Institute of Radiology, Washington University, St Louis, MO. IN - Pope, J Hector. Department of Emergency Medicine, Baystate Medical Center, Springfield, MA. IN - Hauser, Thomas. Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA. IN - Mayrhofer, Thomas. Department of Radiology, Massachusetts General Hospital, Boston, MA. IN - Nagurney, J Toby. Department of Emergency Medicine, Massachusetts General Hospital. IN - Schoenfeld, David. Department of Biostatistics, Massachusetts General Hospital, Boston, MA. IN - Peacock, W Frank. Department of Emergency Medicine, Baylor College of Medicine, Boston, MA. IN - Fleg, Jerome L. Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, MD. IN - Wiviott, Stephen. Department of Medicine, Brigham and Women's Hospital, Boston, MA. IN - Pang, Peter S. Department of Emergency Medicine, Indiana University, Indianapolis, IN. IN - Udelson, James. Department of Medicine, Tufts Medical Center, Boston, MA. IN - Hoffmann, Udo. Division of Cardiology, Massachusetts General Hospital, Boston, MA; Department of Radiology, Massachusetts General Hospital, Boston, MA. TI - Sensitive troponin assays in patients with suspected acute coronary syndrome: Results from the multicenter rule out myocardial infarction using computer assisted tomography II trial. SO - American Heart Journal. 169(4):572-8.e1, 2015 Apr AS - Am Heart J. 169(4):572-8.e1, 2015 Apr NJ - American heart journal PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 0370465 IO - Am. Heart J. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380232 OI - Source: NLM. NIHMS655070 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Acute Coronary Syndrome/bl [Blood] MH - *Acute Coronary Syndrome/dg [Diagnostic Imaging] MH - Biomarkers/bl [Blood] MH - *Early Diagnosis MH - Electrocardiography MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/bl [Blood] MH - *Myocardial Infarction/dg [Diagnostic Imaging] MH - Prospective Studies MH - ROC Curve MH - Reproducibility of Results MH - *Tomography, X-Ray Computed/mt [Methods] MH - *Troponin T/bl [Blood] AB - BACKGROUND: Sensitive troponin (Tn) assays have been developed for the evaluation of patients with suspected acute coronary syndrome (ACS). We sought to compare the performance of a commercially available sensitive Tn I (sTnI) and precommercial highly sTnI (hsTnI) method to conventional Tn (cTn) assays. AB - METHODS: Among patients with acute chest pain but normal cTn in the emergency department of 6 centers, sTnI and hsTnI were measured at baseline, 2 and 4 hours after presentation. Diagnostic accuracy of sTnI and hsTnI relative to cTn for diagnosis during index hospitalization as well as their associations with coronary artery disease in patients randomized to coronary computed tomographic angiography (CTA) was assessed. AB - RESULTS: Overall, 322 patients were enrolled, of whom 161 had a CTA; 28 had ACS (8.7%), including 21 with unstable angina pectoris (UAP). Both sTnI and hsTnI values at baseline and second draw had significantly higher sensitivity for ACS and UAP than cTn and had significantly greater area under the receiver operator characteristic curve than cTn at first and second draws. Compared with cTn, 29% of ACS cases previously categorized as UAP were reclassified to acute myocardial infarction with sTnI or hsTnI. An hsTnI below limit of detection had 100% negative predictive value for ACS or significant coronary artery stenosis in those randomized to CTA. AB - CONCLUSIONS: In patients with acute chest discomfort, use of sTnI and hsTnI methods led to significant improvement in the early diagnostic accuracy for ACS, reclassifying one-third of UAP to myocardial infarction. Very low values for hsTnI excluded underlying coronary artery disease. AB - Copyright © 2015 Elsevier Inc. All rights reserved. RN - 0 (Biomarkers) RN - 0 (Troponin T) ES - 1097-6744 IL - 0002-8703 DI - S0002-8703(15)00051-4 DO - https://dx.doi.org/10.1016/j.ahj.2014.12.023 PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't ID - 25819865 [pubmed] ID - S0002-8703(15)00051-4 [pii] ID - 10.1016/j.ahj.2014.12.023 [doi] ID - PMC4380232 [pmc] ID - NIHMS655070 [mid] PP - ppublish PH - 2014/09/05 [received] PH - 2014/12/20 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01084239 SA - ClinicalTrials.gov/NCT01084239 SL - https://clinicaltrials.gov/search/term=NCT01084239 SL - https://clinicaltrials.gov/search/term=NCT01084239 GI - No: U01 HL092040 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30HL093896 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K23HL098370 Organization: (HL) *NHLBI NIH HHS* Country: United States No: U01HL092040 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30 HL093806 Organization: (HL) *NHLBI NIH HHS* Country: United States No: UO1HL092022 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K24 HL113128 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K23 HL098370 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English EP - 20150109 DP - 2015 Apr DC - 20150330 EZ - 2015/03/31 06:00 DA - 2015/05/27 06:00 DT - 2015/03/31 06:00 YR - 2015 ED - 20150526 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25819865 <196. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25819865 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Januzzi JL AU - Sharma U AU - Zakroysky P AU - Truong QA AU - Woodard PK AU - Pope JH AU - Hauser T AU - Mayrhofer T AU - Nagurney JT AU - Schoenfeld D AU - Peacock WF AU - Fleg JL AU - Wiviott S AU - Pang PS AU - Udelson J AU - Hoffmann U FA - Januzzi, James L FA - Sharma, Umesh FA - Zakroysky, Pearl FA - Truong, Quynh A FA - Woodard, Pamela K FA - Pope, J Hector FA - Hauser, Thomas FA - Mayrhofer, Thomas FA - Nagurney, J Toby FA - Schoenfeld, David FA - Peacock, W Frank FA - Fleg, Jerome L FA - Wiviott, Stephen FA - Pang, Peter S FA - Udelson, James FA - Hoffmann, Udo IN - Januzzi, James L. Division of Cardiology, Massachusetts General Hospital, Boston, MA. Electronic address: JJanuzzi@partners.org. IN - Sharma, Umesh. Department of Radiology, Massachusetts General Hospital, Boston, MA. IN - Zakroysky, Pearl. Department of Biostatistics, Massachusetts General Hospital, Boston, MA. IN - Truong, Quynh A. Division of Cardiology, Massachusetts General Hospital, Boston, MA. IN - Woodard, Pamela K. Mallinkrodt Institute of Radiology, Washington University, St Louis, MO. IN - Pope, J Hector. Department of Emergency Medicine, Baystate Medical Center, Springfield, MA. IN - Hauser, Thomas. Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA. IN - Mayrhofer, Thomas. Department of Radiology, Massachusetts General Hospital, Boston, MA. IN - Nagurney, J Toby. Department of Emergency Medicine, Massachusetts General Hospital. IN - Schoenfeld, David. Department of Biostatistics, Massachusetts General Hospital, Boston, MA. IN - Peacock, W Frank. Department of Emergency Medicine, Baylor College of Medicine, Boston, MA. IN - Fleg, Jerome L. Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, MD. IN - Wiviott, Stephen. Department of Medicine, Brigham and Women's Hospital, Boston, MA. IN - Pang, Peter S. Department of Emergency Medicine, Indiana University, Indianapolis, IN. IN - Udelson, James. Department of Medicine, Tufts Medical Center, Boston, MA. IN - Hoffmann, Udo. Division of Cardiology, Massachusetts General Hospital, Boston, MA; Department of Radiology, Massachusetts General Hospital, Boston, MA. TI - Sensitive troponin assays in patients with suspected acute coronary syndrome: Results from the multicenter rule out myocardial infarction using computer assisted tomography II trial. SO - American Heart Journal. 169(4):572-8.e1, 2015 Apr AS - Am Heart J. 169(4):572-8.e1, 2015 Apr NJ - American heart journal PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 0370465 IO - Am. Heart J. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380232 OI - Source: NLM. NIHMS655070 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Acute Coronary Syndrome/bl [Blood] MH - *Acute Coronary Syndrome/dg [Diagnostic Imaging] MH - Biomarkers/bl [Blood] MH - *Early Diagnosis MH - Electrocardiography MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/bl [Blood] MH - *Myocardial Infarction/dg [Diagnostic Imaging] MH - Prospective Studies MH - ROC Curve MH - Reproducibility of Results MH - *Tomography, X-Ray Computed/mt [Methods] MH - *Troponin T/bl [Blood] AB - BACKGROUND: Sensitive troponin (Tn) assays have been developed for the evaluation of patients with suspected acute coronary syndrome (ACS). We sought to compare the performance of a commercially available sensitive Tn I (sTnI) and precommercial highly sTnI (hsTnI) method to conventional Tn (cTn) assays. AB - METHODS: Among patients with acute chest pain but normal cTn in the emergency department of 6 centers, sTnI and hsTnI were measured at baseline, 2 and 4 hours after presentation. Diagnostic accuracy of sTnI and hsTnI relative to cTn for diagnosis during index hospitalization as well as their associations with coronary artery disease in patients randomized to coronary computed tomographic angiography (CTA) was assessed. AB - RESULTS: Overall, 322 patients were enrolled, of whom 161 had a CTA; 28 had ACS (8.7%), including 21 with unstable angina pectoris (UAP). Both sTnI and hsTnI values at baseline and second draw had significantly higher sensitivity for ACS and UAP than cTn and had significantly greater area under the receiver operator characteristic curve than cTn at first and second draws. Compared with cTn, 29% of ACS cases previously categorized as UAP were reclassified to acute myocardial infarction with sTnI or hsTnI. An hsTnI below limit of detection had 100% negative predictive value for ACS or significant coronary artery stenosis in those randomized to CTA. AB - CONCLUSIONS: In patients with acute chest discomfort, use of sTnI and hsTnI methods led to significant improvement in the early diagnostic accuracy for ACS, reclassifying one-third of UAP to myocardial infarction. Very low values for hsTnI excluded underlying coronary artery disease. AB - Copyright © 2015 Elsevier Inc. All rights reserved. RN - 0 (Biomarkers) RN - 0 (Troponin T) ES - 1097-6744 IL - 0002-8703 DI - S0002-8703(15)00051-4 DO - https://dx.doi.org/10.1016/j.ahj.2014.12.023 PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't ID - 25819865 [pubmed] ID - S0002-8703(15)00051-4 [pii] ID - 10.1016/j.ahj.2014.12.023 [doi] ID - PMC4380232 [pmc] ID - NIHMS655070 [mid] PP - ppublish PH - 2014/09/05 [received] PH - 2014/12/20 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01084239 SL - https://clinicaltrials.gov/search/term=NCT01084239 GI - No: U01 HL092040 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30HL093896 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K23HL098370 Organization: (HL) *NHLBI NIH HHS* Country: United States No: U01HL092040 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30 HL093806 Organization: (HL) *NHLBI NIH HHS* Country: United States No: UO1HL092022 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K24 HL113128 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K23 HL098370 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English EP - 20150109 DP - 2015 Apr DC - 20150330 EZ - 2015/03/31 06:00 DA - 2015/05/27 06:00 DT - 2015/03/31 06:00 YR - 2015 ED - 20150526 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=25819865 <197. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25789947 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Cho MS AU - Baek SJ AU - Hur H AU - Min BS AU - Baik SH AU - Lee KY AU - Kim NK FA - Cho, Min Soo FA - Baek, Se Jin FA - Hur, Hyuk FA - Min, Byung Soh FA - Baik, Seung Hyuk FA - Lee, Kang Young FA - Kim, Nam Kyu IN - Cho, Min Soo. From the Department of Surgery, Division of Colon and Rectal surgery, Yonsei University College of Medicine, Seoul, Korea. TI - Short and long-term outcomes of robotic versus laparoscopic total mesorectal excision for rectal cancer: a case-matched retrospective study. SO - Medicine. 94(11):e522, 2015 Mar AS - Medicine (Baltimore). 94(11):e522, 2015 Mar NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602485 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adenocarcinoma/pa [Pathology] MH - *Adenocarcinoma/su [Surgery] MH - Aged MH - Digestive System Surgical Procedures/mt [Methods] MH - *Digestive System Surgical Procedures/sn [Statistics & Numerical Data] MH - Female MH - Humans MH - Laparoscopy/sn [Statistics & Numerical Data] MH - Lymph Nodes/pa [Pathology] MH - Male MH - Middle Aged MH - *Neoplasm Recurrence, Local/ep [Epidemiology] MH - Postoperative Complications/ep [Epidemiology] MH - Postoperative Period MH - Rectal Neoplasms/pa [Pathology] MH - *Rectal Neoplasms/su [Surgery] MH - Republic of Korea/ep [Epidemiology] MH - Retrospective Studies MH - Robotics/sn [Statistics & Numerical Data] AB - The true benefits of robotic surgery are controversial, and whether robotic total mesorectal excision (R-TME) can be justified as a standard treatment for rectal cancer patients needs to be clarified. This case-matched study aimed to compare the postoperative complications and short- and long-term outcomes of R-TME and laparoscopic TME (L-TME) for rectal cancer.Among 1029 patients, we identified 278 rectal cancer patients who underwent R-TME. Propensity score matching was used to match this group with 278 patients who underwent L-TME.The mean follow-up period was similar between both groups (L-TME vs R-TME: 52.5 +/- 17.1 vs 51.0 +/- 13.1 months, P = 0.253), as were patient characteristics. The operation time was significantly longer in the R-TME group than in the L-TME group (361.6 +/- 91.9 vs 272.4 +/- 83.8 min; P < 0.001), whereas the conversion rate, length of hospital stay, and recovery of pain and bowel motility were similar between both groups. The rates of circumferential resection margin involvement and early complications were similar between both groups (L-TME vs R-TME: 4.7% vs 5.0%, P = 1.000; and 23.7% vs 25.9%, P = 0.624, respectively), as were the 5-year overall survival, disease-free survival, and local recurrence rates (93.1% vs 92.2%, P = 0.422; 79.6% vs 81.8%, P = 0.538; 3.9% vs 5.9%, P = 0.313, respectively).The oncologic quality, short- and long-term outcomes, and postoperative morbidity in the R-TME group were comparable with those in the L-TME group. ES - 1536-5964 IL - 0025-7974 DI - 00005792-201503030-00006 DO - https://dx.doi.org/10.1097/MD.0000000000000522 PT - Comparative Study PT - Journal Article PT - Observational Study ID - 25789947 [pubmed] ID - 10.1097/MD.0000000000000522 [doi] ID - 00005792-201503030-00006 [pii] ID - PMC4602485 [pmc] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01196000 SA - ClinicalTrials.gov/NCT01423214 SL - https://clinicaltrials.gov/search/term=NCT01196000 SL - https://clinicaltrials.gov/search/term=NCT01423214 LG - English DP - 2015 Mar DC - 20150320 EZ - 2015/03/20 06:00 DA - 2015/05/26 06:00 DT - 2015/03/20 06:00 YR - 2015 ED - 20150525 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25789947 <198. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25086483 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Rosendal C AU - Markin S AU - Hien MD AU - Motsch J AU - Roggenbach J FA - Rosendal, Christian FA - Markin, Sergei FA - Hien, Maximilian D FA - Motsch, Johann FA - Roggenbach, Jens IN - Rosendal, Christian. Hirslanden Clinics Berne, Klinik Beau-Site, Schanzlihalde 11, 3000 Bern 25, Switzerland; Department of Anesthesiology, University of Heidelberg, INF 110, 69120 Heidelberg, Germany. Electronic address: chh7@gmx.de. IN - Markin, Sergei. Department of Anesthesiology, University of Heidelberg, INF 110, 69120 Heidelberg, Germany. IN - Hien, Maximilian D. Research Training Group 1126, University of Heidelberg, German Research Foundation (DFG), INF 110, 69120 Heidelberg, Germany; Department of Pediatrics, University of Heidelberg, INF 430, 69120 Heidelberg, Germany. IN - Motsch, Johann. Department of Anesthesiology, University of Heidelberg, INF 110, 69120 Heidelberg, Germany. IN - Roggenbach, Jens. Department of Anesthesiology, University of Heidelberg, INF 110, 69120 Heidelberg, Germany. TI - Cardiac and hemodynamic consequences during capnoperitoneum and steep Trendelenburg positioning: lessons learned from robot-assisted laparoscopic prostatectomy. SO - Journal of Clinical Anesthesia. 26(5):383-9, 2014 Aug AS - J Clin Anesth. 26(5):383-9, 2014 Aug NJ - Journal of clinical anesthesia PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - an9, 8812166 IO - J Clin Anesth SB - Index Medicus CP - United States MH - Aged MH - Anesthesia/mt [Methods] MH - *Head-Down Tilt/ph [Physiology] MH - Heart Rate/ph [Physiology] MH - Hemodynamics/ph [Physiology] MH - Hospitals, University MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - *Pneumoperitoneum, Artificial/mt [Methods] MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - Robotics MH - Thermodilution/mt [Methods] KW - Cardiac output: afterload, preload; Robot-assisted laparoscopic prostatectomy; Transpulmonary thermodiluation AB - STUDY OBJECTIVE: To determine and interpret the changes in preload, afterload, and cardiac function in the different phases of robot-assisted laparoscopic prostatectomy. AB - DESIGN: Prospective, observational monocenter study. AB - SETTING: Operating room at a university hospital. AB - PATIENTS: 31 consecutive, ASA physical status 1, 2, and 3 patients. AB - INTERVENTIONS: Observations were made at 5 distinct time points: baseline after induction of anesthesia, after initiation of capnoperitoneum, immediately after a 45degree head-down tilt, 15 minutes after the 45degree head-down tilt was established, after the release of the capnoperitoneum, and 5 minutes after the patient was returned to a horizontal position (end). AB - MEASUREMENTS: Transpulmonary thermodilution and pulse contour analysis were used to record hemodynamic changes in preload, afterload, and cardiac function. AB - MAIN RESULTS: While central venous pressure increased threefold from baseline, none of the other preload parameters showed excessive fluid overload or demand. There was no significant change in cardiac contractility over time. Afterload increased significantly during the capnoperitoneum and significantly decreased compared with baseline after the release of abdominal pressure at the end of the procedure. Heart rate and cardiac index increased significantly during robot-assisted laparoscopic prostatectomy. AB - CONCLUSIONS: Selective arterial vasodilation at the time of capnoperitoneum may normalize afterload and myocardial oxygen demand. AB - Copyright © 2014 Elsevier Inc. All rights reserved. ES - 1873-4529 IL - 0952-8180 DI - S0952-8180(14)00100-7 DO - https://dx.doi.org/10.1016/j.jclinane.2014.01.014 PT - Journal Article PT - Observational Study ID - 25086483 [pubmed] ID - S0952-8180(14)00100-7 [pii] ID - 10.1016/j.jclinane.2014.01.014 [doi] PP - ppublish PH - 2013/02/19 [received] PH - 2014/01/01 [revised] PH - 2014/01/19 [accepted] LG - English EP - 20140730 DP - 2014 Aug DC - 20140911 EZ - 2014/08/04 06:00 DA - 2015/05/26 06:00 DT - 2014/08/05 06:00 YR - 2014 ED - 20150525 RD - 20140911 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25086483 <199. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25789947 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Cho MS AU - Baek SJ AU - Hur H AU - Min BS AU - Baik SH AU - Lee KY AU - Kim NK FA - Cho, Min Soo FA - Baek, Se Jin FA - Hur, Hyuk FA - Min, Byung Soh FA - Baik, Seung Hyuk FA - Lee, Kang Young FA - Kim, Nam Kyu IN - Cho, Min Soo. From the Department of Surgery, Division of Colon and Rectal surgery, Yonsei University College of Medicine, Seoul, Korea. TI - Short and long-term outcomes of robotic versus laparoscopic total mesorectal excision for rectal cancer: a case-matched retrospective study. SO - Medicine. 94(11):e522, 2015 Mar AS - Medicine (Baltimore). 94(11):e522, 2015 Mar NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602485 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adenocarcinoma/pa [Pathology] MH - *Adenocarcinoma/su [Surgery] MH - Aged MH - Digestive System Surgical Procedures/mt [Methods] MH - *Digestive System Surgical Procedures/sn [Statistics & Numerical Data] MH - Female MH - Humans MH - Laparoscopy/sn [Statistics & Numerical Data] MH - Lymph Nodes/pa [Pathology] MH - Male MH - Middle Aged MH - *Neoplasm Recurrence, Local/ep [Epidemiology] MH - Postoperative Complications/ep [Epidemiology] MH - Postoperative Period MH - Rectal Neoplasms/pa [Pathology] MH - *Rectal Neoplasms/su [Surgery] MH - Republic of Korea/ep [Epidemiology] MH - Retrospective Studies MH - Robotics/sn [Statistics & Numerical Data] AB - The true benefits of robotic surgery are controversial, and whether robotic total mesorectal excision (R-TME) can be justified as a standard treatment for rectal cancer patients needs to be clarified. This case-matched study aimed to compare the postoperative complications and short- and long-term outcomes of R-TME and laparoscopic TME (L-TME) for rectal cancer.Among 1029 patients, we identified 278 rectal cancer patients who underwent R-TME. Propensity score matching was used to match this group with 278 patients who underwent L-TME.The mean follow-up period was similar between both groups (L-TME vs R-TME: 52.5 +/- 17.1 vs 51.0 +/- 13.1 months, P = 0.253), as were patient characteristics. The operation time was significantly longer in the R-TME group than in the L-TME group (361.6 +/- 91.9 vs 272.4 +/- 83.8 min; P < 0.001), whereas the conversion rate, length of hospital stay, and recovery of pain and bowel motility were similar between both groups. The rates of circumferential resection margin involvement and early complications were similar between both groups (L-TME vs R-TME: 4.7% vs 5.0%, P = 1.000; and 23.7% vs 25.9%, P = 0.624, respectively), as were the 5-year overall survival, disease-free survival, and local recurrence rates (93.1% vs 92.2%, P = 0.422; 79.6% vs 81.8%, P = 0.538; 3.9% vs 5.9%, P = 0.313, respectively).The oncologic quality, short- and long-term outcomes, and postoperative morbidity in the R-TME group were comparable with those in the L-TME group. ES - 1536-5964 IL - 0025-7974 DI - 00005792-201503030-00006 DO - https://dx.doi.org/10.1097/MD.0000000000000522 PT - Comparative Study PT - Journal Article PT - Observational Study ID - 25789947 [pubmed] ID - 10.1097/MD.0000000000000522 [doi] ID - 00005792-201503030-00006 [pii] ID - PMC4602485 [pmc] PP - ppublish LG - English DP - 2015 Mar DC - 20150320 EZ - 2015/03/20 06:00 DA - 2015/05/26 06:00 DT - 2015/03/20 06:00 YR - 2015 ED - 20150525 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=25789947 <200. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24411228 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lee JH AU - Kim JG AU - Oh ST AU - Lee MA AU - Chun HG AU - Kim DY AU - Kim TH AU - Kim SY AU - Baek JY AU - Park JW AU - Oh JH AU - Park HC AU - Choi DH AU - Park YS AU - Kim HC AU - Chie EK AU - Jang HS FA - Lee, Jong Hoon FA - Kim, Jun-Gi FA - Oh, Seong Taek FA - Lee, Myung Ah FA - Chun, Hoo Geun FA - Kim, Dae Yong FA - Kim, Tae Hyun FA - Kim, Sun Young FA - Baek, Ji Yeon FA - Park, Ji Won FA - Oh, Jae Hwan FA - Park, Hee Chul FA - Choi, Doo Ho FA - Park, Young Suk FA - Kim, Hee Cheol FA - Chie, Eui Kyu FA - Jang, Hong Seok IN - Lee, Jong Hoon. Department of Radiation Oncology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea. IN - Kim, Jun-Gi. Department of Colorectal Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea. IN - Oh, Seong Taek. Department of Colorectal Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea. IN - Lee, Myung Ah. Department of Medical Oncology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea. IN - Chun, Hoo Geun. Department of Medical Oncology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea. IN - Kim, Dae Yong. Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Go-Yang, Republic of Korea. IN - Kim, Tae Hyun. Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Go-Yang, Republic of Korea. IN - Kim, Sun Young. Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Go-Yang, Republic of Korea. IN - Baek, Ji Yeon. Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Go-Yang, Republic of Korea. IN - Park, Ji Won. Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Go-Yang, Republic of Korea. IN - Oh, Jae Hwan. Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Go-Yang, Republic of Korea. IN - Park, Hee Chul. Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. IN - Choi, Doo Ho. Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. IN - Park, Young Suk. Department of Internal Medicine, Division of Hematology-Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. IN - Kim, Hee Cheol. Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. IN - Chie, Eui Kyu. Department of Radiation Oncology, Seoul National University College of Medicine, Republic of Korea. IN - Jang, Hong Seok. Department of Radiation Oncology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea. Electronic address: hsjang11@catholic.ac.kr. TI - Two-week course of preoperative chemoradiotherapy followed by delayed surgery for rectal cancer: a phase II multi-institutional clinical trial (KROG 11-02). SO - Radiotherapy & Oncology. 110(1):150-4, 2014 Jan AS - Radiother Oncol. 110(1):150-4, 2014 Jan NJ - Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - rae, 8407192 IO - Radiother Oncol SB - Index Medicus CP - Ireland MH - Administration, Oral MH - Adult MH - Aged MH - Aged, 80 and over MH - *Antimetabolites, Antineoplastic/ad [Administration & Dosage] MH - Capecitabine MH - Chemoradiotherapy MH - Deoxycytidine/ad [Administration & Dosage] MH - *Deoxycytidine/aa [Analogs & Derivatives] MH - Female MH - Fluorouracil/ad [Administration & Dosage] MH - *Fluorouracil/aa [Analogs & Derivatives] MH - Humans MH - Male MH - Middle Aged MH - Preoperative Care MH - Prospective Studies MH - Rectal Neoplasms/dt [Drug Therapy] MH - Rectal Neoplasms/rt [Radiotherapy] MH - Rectal Neoplasms/su [Surgery] MH - *Rectal Neoplasms/th [Therapy] MH - Remission Induction KW - Preoperative chemoradiotherapy; Rectal cancer; Total mesorectal excision; Two-week course AB - PURPOSE: The aim of this study was to evaluate the efficacy and safety of a two-week schedule of radiotherapy with oral capecitabine in locally advanced rectal cancer. AB - METHODS AND MATERIALS: Eighty patients with rectal cancer located in the mid to low rectum, staged cT3-4N0-2M0, were prospectively enrolled. They underwent preoperative chemoradiotherapy and delayed surgery 6-8 weeks after the completion of radiation therapy. A radiation dose of 33 Gy in 10 fractions was delivered to the pelvis for 2 weeks. One cycle of oral capecitabine was administered at a dose of 1650 mg/m(2)/day during radiotherapy. Tumor response and toxicity were the study endpoints. This study was registered at ClinicalTrials.gov (number, NCT01431599). AB - RESULTS: All included patients underwent total mesorectal excisions including 12 cases of robot assisted surgery and 50 cases of laparoscopic surgery. Of the 80 patients, 27 (33.8%) achieved downstaging (ypT0-2N0) of a rectal tumor and 11 (13.8%) had a pathologically complete response (ypCR). Downstaging rates were 45% for T classification and 65% for N classification. Sphincter saving was achieved in 73 (91.3%) of the 80 patients. Of the 80 patients, 3 (3.8%) experienced grade 3 hematologic toxicity, and 2 (2.5%) had grade 3 postoperative complications such as ileus and wound dehiscence. There was no grade 4 toxicity. AB - CONCLUSION: A two-week schedule of radiotherapy with oral capecitabine in locally advanced rectal cancer patients showed low toxicity profiles and promising results in terms of tumor response. AB - Copyright © 2013 Elsevier Ireland Ltd. All rights reserved. RN - 0 (Antimetabolites, Antineoplastic) RN - 0W860991D6 (Deoxycytidine) RN - 6804DJ8Z9U (Capecitabine) RN - U3P01618RT (Fluorouracil) ES - 1879-0887 IL - 0167-8140 DI - S0167-8140(13)00640-3 DO - https://dx.doi.org/10.1016/j.radonc.2013.11.013 PT - Clinical Trial, Phase II PT - Journal Article PT - Multicenter Study PT - Research Support, Non-U.S. Gov't ID - 24411228 [pubmed] ID - S0167-8140(13)00640-3 [pii] ID - 10.1016/j.radonc.2013.11.013 [doi] PP - ppublish PH - 2013/02/27 [received] PH - 2013/10/16 [revised] PH - 2013/11/09 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01431599 SL - https://clinicaltrials.gov/search/term=NCT01431599 LG - English EP - 20140107 DP - 2014 Jan DC - 20140318 EZ - 2014/01/14 06:00 DA - 2015/05/23 06:00 DT - 2014/01/15 06:00 YR - 2014 ED - 20150521 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24411228 <201. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25721452 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Cundy TP AU - Thangaraj E AU - Rafii-Tari H AU - Payne CJ AU - Azzie G AU - Sodergren MH AU - Yang GZ AU - Darzi A FA - Cundy, Thomas P FA - Thangaraj, Evelyn FA - Rafii-Tari, Hedyeh FA - Payne, Christopher J FA - Azzie, Georges FA - Sodergren, Mikael H FA - Yang, Guang-Zhong FA - Darzi, Ara IN - Cundy, Thomas P. The Hamlyn Centre, Institute of Global Health Innovation, Imperial College London, London, United Kingdom; Department of Surgery and Cancer, Imperial College London, London, United Kingdom. Electronic address: t.cundy@imperial.ac.uk. IN - Thangaraj, Evelyn. Department of Surgery and Cancer, Imperial College London, London, United Kingdom. IN - Rafii-Tari, Hedyeh. The Hamlyn Centre, Institute of Global Health Innovation, Imperial College London, London, United Kingdom. IN - Payne, Christopher J. The Hamlyn Centre, Institute of Global Health Innovation, Imperial College London, London, United Kingdom. IN - Azzie, Georges. Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada. IN - Sodergren, Mikael H. The Hamlyn Centre, Institute of Global Health Innovation, Imperial College London, London, United Kingdom; Department of Surgery and Cancer, Imperial College London, London, United Kingdom. IN - Yang, Guang-Zhong. The Hamlyn Centre, Institute of Global Health Innovation, Imperial College London, London, United Kingdom. IN - Darzi, Ara. The Hamlyn Centre, Institute of Global Health Innovation, Imperial College London, London, United Kingdom; Department of Surgery and Cancer, Imperial College London, London, United Kingdom. TI - Force-Sensing Enhanced Simulation Environment (ForSense) for laparoscopic surgery training and assessment. SO - Surgery. 157(4):723-31, 2015 Apr AS - Surgery. 157(4):723-31, 2015 Apr NJ - Surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vc3, 0417347 IO - Surgery SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - *Clinical Competence MH - *Computer Simulation MH - Humans MH - *Laparoscopy/ed [Education] MH - London MH - Male MH - *Mechanical Phenomena MH - Models, Educational MH - Ontario MH - Reproducibility of Results MH - Robotics MH - Software MH - *Task Performance and Analysis MH - User-Computer Interface MH - Video Recording AB - BACKGROUND: Excessive or inappropriate tissue interaction force during laparoscopic surgery is a recognized contributor to surgical error, especially for robotic surgery. Measurement of force at the tool-tissue interface is, therefore, a clinically relevant skill assessment variable that may improve effectiveness of surgical simulation. Popular box trainer simulators lack the necessary technology to measure force. The aim of this study was to develop a force sensing unit that may be integrated easily with existing box trainer simulators and to (1) validate multiple force variables as objective measurements of laparoscopic skill, and (2) determine concurrent validity of a revised scoring metric. AB - METHODS: A base plate unit sensitized to a force transducer was retrofitted to a box trainer. Participants of 3 different levels of operative experience performed 5 repetitions of a peg transfer and suture task. Multiple outcome variables of force were assessed as well as a revised scoring metric that incorporated a penalty for force error. AB - RESULTS: Mean, maximum, and overall magnitudes of force were significantly different among the 3 levels of experience, as well as force error. Experts were found to exert the least force and fastest task completion times, and vice versa for novices. Overall magnitude of force was the variable most correlated with experience level and task completion time. The revised scoring metric had similar predictive strength for experience level compared with the standard scoring metric. AB - CONCLUSION: Current box trainer simulators can be adapted for enhanced objective measurements of skill involving force sensing. These outcomes are significantly influenced by level of expertise and are relevant to operative safety in laparoscopic surgery. Conventional proficiency standards that focus predominantly on task completion time may be integrated with force-based outcomes to be more accurately reflective of skill quality. AB - Copyright © 2015 Elsevier Inc. All rights reserved. ES - 1532-7361 IL - 0039-6060 DI - S0039-6060(14)00711-9 DO - https://dx.doi.org/10.1016/j.surg.2014.10.015 PT - Clinical Trial PT - Journal Article ID - 25721452 [pubmed] ID - S0039-6060(14)00711-9 [pii] ID - 10.1016/j.surg.2014.10.015 [doi] PP - ppublish PH - 2014/02/28 [received] PH - 2014/09/27 [revised] PH - 2014/10/24 [accepted] LG - English EP - 20150224 DP - 2015 Apr DC - 20150321 EZ - 2015/02/28 06:00 DA - 2015/05/20 06:00 DT - 2015/02/28 06:00 YR - 2015 ED - 20150518 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25721452 <202. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25733270 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lista G AU - Buffi NM AU - Lughezzani G AU - Lazzeri M AU - Abrate A AU - Mistretta A AU - Larcher A AU - Dell'Oglio P AU - Fossati N AU - Porter J AU - Ficarra V AU - Mottrie A AU - Guazzoni G FA - Lista, Giuliana FA - Buffi, Nicolo Maria FA - Lughezzani, Giovanni FA - Lazzeri, Massimo FA - Abrate, Alberto FA - Mistretta, Alessandro FA - Larcher, Alessandro FA - Dell'Oglio, Paolo FA - Fossati, Nicola FA - Porter, James FA - Ficarra, Vincenzo FA - Mottrie, Alexander FA - Guazzoni, Giorgio IN - Lista, Giuliana. Division of Oncology, Unit of Urology, URI, IRCCS Ospedale San Raffaele Turro, Universita Vita-Salute San Raffaele, Milan, Italy. Electronic address: giulianalista@gmail.com. IN - Buffi, Nicolo Maria. Division of Oncology, Unit of Urology, URI, IRCCS Ospedale San Raffaele Turro, Universita Vita-Salute San Raffaele, Milan, Italy. IN - Lughezzani, Giovanni. Division of Oncology, Unit of Urology, URI, IRCCS Ospedale San Raffaele Turro, Universita Vita-Salute San Raffaele, Milan, Italy. IN - Lazzeri, Massimo. Division of Oncology, Unit of Urology, URI, IRCCS Ospedale San Raffaele Turro, Universita Vita-Salute San Raffaele, Milan, Italy. IN - Abrate, Alberto. Division of Oncology, Unit of Urology, URI, IRCCS Ospedale San Raffaele Turro, Universita Vita-Salute San Raffaele, Milan, Italy. IN - Mistretta, Alessandro. Division of Oncology, Unit of Urology, URI, IRCCS Ospedale San Raffaele Turro, Universita Vita-Salute San Raffaele, Milan, Italy. IN - Larcher, Alessandro. Division of Oncology, Unit of Urology, URI, IRCCS Ospedale San Raffaele Turro, Universita Vita-Salute San Raffaele, Milan, Italy. IN - Dell'Oglio, Paolo. Division of Oncology, Unit of Urology, URI, IRCCS Ospedale San Raffaele Turro, Universita Vita-Salute San Raffaele, Milan, Italy. IN - Fossati, Nicola. Division of Oncology, Unit of Urology, URI, IRCCS Ospedale San Raffaele Turro, Universita Vita-Salute San Raffaele, Milan, Italy. IN - Porter, James. Swedish Urology Group, Seattle, WA. IN - Ficarra, Vincenzo. Division of Urology, OLV Vattikuti Robotic Surgery Institute, Aalst, Belgium. IN - Mottrie, Alexander. Division of Urology, OLV Vattikuti Robotic Surgery Institute, Aalst, Belgium. IN - Guazzoni, Giorgio. Division of Oncology, Unit of Urology, URI, IRCCS Ospedale San Raffaele Turro, Universita Vita-Salute San Raffaele, Milan, Italy. TI - Margin, ischemia, and complications system to report perioperative outcomes of robotic partial nephrectomy: a European Multicenter Observational Study (EMOS project). CM - Comment in: Urology. 2015 Mar;85(3):595; PMID: 25733272 CM - Comment in: Urology. 2015 Mar;85(3):594-5; PMID: 25733271 SO - Urology. 85(3):589-95, 2015 Mar AS - Urology. 85(3):589-95, 2015 Mar NJ - Urology PI - Journal available in: Print PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - Europe MH - Female MH - Humans MH - *Kidney Neoplasms/pa [Pathology] MH - *Kidney Neoplasms/su [Surgery] MH - Male MH - Middle Aged MH - *Nephrectomy/ae [Adverse Effects] MH - *Nephrectomy/mt [Methods] MH - Prospective Studies MH - *Robotic Surgical Procedures/ae [Adverse Effects] MH - Treatment Outcome MH - Warm Ischemia AB - OBJECTIVE: To explore the margin, ischemia, and complications (MIC) system achievement rate within a population of patients who were treated with robotic partial nephrectomy (RAPN), at 3 different tertiary care centers, and to determine the factors predicting MIC achievement. AB - METHODS: The study population consisted of 339 patients who underwent RAPN for cT1 renal tumors at 3 centers. Cancer control was defined as the absence of positive surgical margin. Ideal threshold of warm ischemia time (WIT) was considered <20 minutes. Safety was defined as the absence of major complications. The achievement of MIC was considered as the fulfillment of all these 3 outcomes. The primary endpoint was to determine the MIC rate in our study population; the secondary endpoint was to detect factors affecting its achievement. AB - RESULTS: The overall MIC rate was 67%. Median WIT was 17 minutes (range, 7-51 minutes). In 88 cases (26%), WIT was >20 minutes. Positive surgical margins were found in 22 patients (6.5%). Overall postoperative and major complication rates were 14.5% (n = 49) and 3.8% (n = 13). In multivariate logistic regression analysis, continuously coded and categorically coded preoperative aspects and dimensions used for an anatomical scores were an independent predictor of MIC achievement (odds ratio, 0.636; confidence interval, 0.436-0.928; P = .019 and odds ratio, 0.098; confidence interval, 0.030-0.326; P <.001). AB - CONCLUSION: The MIC binary system may represent a useful tool to summarize the achievement of optimal perioperative outcomes of RAPN. In the current population, tumor complexity was significantly associated with MIC achievement. AB - Copyright © 2015 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(14)01304-1 DO - https://dx.doi.org/10.1016/j.urology.2014.09.068 PT - Evaluation Studies PT - Journal Article PT - Multicenter Study PT - Observational Study ID - 25733270 [pubmed] ID - S0090-4295(14)01304-1 [pii] ID - 10.1016/j.urology.2014.09.068 [doi] PP - ppublish PH - 2014/03/07 [received] PH - 2014/07/28 [revised] PH - 2014/09/19 [accepted] LG - English DP - 2015 Mar DC - 20150303 EZ - 2015/03/04 06:00 DA - 2015/05/06 06:00 DT - 2015/03/04 06:00 YR - 2015 ED - 20150504 RD - 20150303 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25733270 <203. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25562434 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Trillsch F AU - Mahner S AU - Vettorazzi E AU - Woelber L AU - Reuss A AU - Baumann K AU - Keyver-Paik MD AU - Canzler U AU - Wollschlaeger K AU - Forner D AU - Pfisterer J AU - Schroeder W AU - Muenstedt K AU - Richter B AU - Fotopoulou C AU - Schmalfeldt B AU - Burges A AU - Ewald-Riegler N AU - de Gregorio N AU - Hilpert F AU - Fehm T AU - Meier W AU - Hillemanns P AU - Hanker L AU - Hasenburg A AU - Strauss HG AU - Hellriegel M AU - Wimberger P AU - Kommoss S AU - Kommoss F AU - Hauptmann S AU - du Bois A FA - Trillsch, F FA - Mahner, S FA - Vettorazzi, E FA - Woelber, L FA - Reuss, A FA - Baumann, K FA - Keyver-Paik, M-D FA - Canzler, U FA - Wollschlaeger, K FA - Forner, D FA - Pfisterer, J FA - Schroeder, W FA - Muenstedt, K FA - Richter, B FA - Fotopoulou, C FA - Schmalfeldt, B FA - Burges, A FA - Ewald-Riegler, N FA - de Gregorio, N FA - Hilpert, F FA - Fehm, T FA - Meier, W FA - Hillemanns, P FA - Hanker, L FA - Hasenburg, A FA - Strauss, H-G FA - Hellriegel, M FA - Wimberger, P FA - Kommoss, S FA - Kommoss, F FA - Hauptmann, S FA - du Bois, A IN - Trillsch, F. Universitaetsklinikum Hamburg-Eppendorf, Klinik und Poliklinik fuer Gynaekologie, Martinistr. 52, 20246 Hamburg, Germany. IN - Mahner, S. Universitaetsklinikum Hamburg-Eppendorf, Klinik und Poliklinik fuer Gynaekologie, Martinistr. 52, 20246 Hamburg, Germany. IN - Vettorazzi, E. Universitaetsklinikum Hamburg-Eppendorf, Institut fuer Medizinische Biometrie und Epidemiologie, Martinistr. 52, 20246 Hamburg, Germany. IN - Woelber, L. Universitaetsklinikum Hamburg-Eppendorf, Klinik und Poliklinik fuer Gynaekologie, Martinistr. 52, 20246 Hamburg, Germany. IN - Reuss, A. Philipps-Universitaet Marburg, Koordinierungszentrum fuer Klinische Studien, Karl-von-Frisch-Str. 4, 35043 Marburg, Germany. IN - Baumann, K. Universitaetsklinikum Giessen u. Marburg GmbH, Klinik fuer Gynaekologie, Gyn. Endokrinologie und Onkologie, Baldingerstr., 35043 Marburg, Germany. IN - Keyver-Paik, M-D. Rheinische Friedrich-Wilhelms-Universitaet, Universitaets-Frauenklinik, Sigmund-Freud-Str. 25, 53127 Bonn, Germany. IN - Canzler, U. Technische Universitaet Dresden, Klinik und Poliklinik fuer Frauenheilkunde und Geburtshilfe, Fetscherstr. 74, 01307 Dresden, Germany. IN - Wollschlaeger, K. Universitaetsklinikum Magdeburg, Universitaets-Frauenklinik, Gerhart-Hauptmann-Str. 35, 39108 Magdeburg, Germany. IN - Forner, D. Sana-Klinikum Remscheid, Klinik fuer Frauenheilkunde und Geburtsmedizin, Burger Strasse 211, 42859 Remscheid, Germany. IN - Pfisterer, J. 1] Staedtisches Klinikum Solingen gGmbH, Klinik fuer Gynaekologie und Geburtshilfe, Gotenstrasse 1, 42653 Solingen, Germany [2] Zentrum fuer Gynaekologische Onkologie, Herzog-Friedrich-Str. 21, 24103 Kiel, Germany. IN - Schroeder, W. GYNAEKOLOGICUM Bremen, Schwachhauser Heerstrasse 367, 28211 Bremen, Germany. IN - Muenstedt, K. Universitaetsklinikum Giessen, Zentrum fuer Frauenheilkunde und Geburtshilfe, Klinikstrasse 33, 35352 Giessen, Germany. IN - Richter, B. Elblandkliniken Meissen-Radebeul GmbH & Co. KG, Frauenklinik, Heinrich-Zille-Str. 13, 01445 Radebeul, Germany. IN - Fotopoulou, C. Charite, Campus Virchow Klinikum, Frauenklinik, Augustenburger Platz 1, 13353 Berlin, Germany. IN - Schmalfeldt, B. Klinikum rechts der Isar der Technischen Universitaet, Frauen- und Poliklinik, Ismaninger Str. 22, 81675 Munich, Germany. IN - Burges, A. Klinikum der Universitaet Muenchen, Campus Grosshadern, Klinik und Poliklinik fuer Frauenheilkunde und Geburtshilfe, Marchioninistr.15, 81377 Munich, Germany. IN - Ewald-Riegler, N. Dr Horst Schmidt Klinik GmbH, Klinik fuer Gynaekologie und gynaekologische Onkologie, Ludwig-Erhard-Str. 100, 65199 Wiesbaden, Germany. IN - de Gregorio, N. Universitaetsklinikum Ulm, Frauenklinik, Prittwitzstrasse 43, 89075 Ulm, Germany. IN - Hilpert, F. Universitaetsklinikum Schleswig-Holstein, Campus Kiel, Klinik fuer Gynaekologie und Geburtshilfe, Michaelisstrasse 16, 24105 Kiel, Germany. IN - Fehm, T. 1] Universitaetsklinikum Tuebingen, Department fuer Frauengesundheit, Calwerstrasse 7, 72076 Tuebingen, Germany [2] Universitaetsklinikum Duesseldorf, Universitaetsfrauenklinik, Moorenstrasse 5, 40225 Duesseldorf, Germany. IN - Meier, W. Evangelisches Krankenhaus, Frauenklinik, Kirchfeldstrasse 40, 40217 Duesseldorf, Germany. IN - Hillemanns, P. Medizinische Hochschule Hannover, Frauenklinik, Carl-Neuberg-Str. 1, 30625 Hannover, Germany. IN - Hanker, L. 1] Klinikum der J.W. Goethe-Universitaet, Zentrum fuer Frauenheilkunde und Geburtshilfe, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany [2] Universitaetsklinikum Schleswig-Holstein, Campus Luebeck, Klinik fuer Gynaekologie und Geburtshilfe, Ratzeburger Allee 160, 23562 Luebeck, Germany. IN - Hasenburg, A. Universitaetsklinikum Freiburg, Frauenklinik, Hugstetter Str. 55, 79106 Freiburg im Breisgau, Germany. IN - Strauss, H-G. Universitaetsklinikum Halle (Saale), Universitaetsklinik und Poliklinik fuer Gynaekologie, Ernst-Grube-Str. 40, 06120 Halle (Saale), Germany. IN - Hellriegel, M. Georg-August-Universitaet Goettingen, Gynaekologie und Geburtshilfe, Robert-Koch-Str. 40, 37075 Goettingen, Germany. IN - Wimberger, P. 1] Technische Universitaet Dresden, Klinik und Poliklinik fuer Frauenheilkunde und Geburtshilfe, Fetscherstr. 74, 01307 Dresden, Germany [2] Universitaetsklinikum Essen, Klinik fuer Frauenheilkunde und Geburtshilfe, Essen, Germany. IN - Kommoss, S. 1] Dr Horst Schmidt Klinik GmbH, Klinik fuer Gynaekologie und gynaekologische Onkologie, Ludwig-Erhard-Str. 100, 65199 Wiesbaden, Germany [2] Universitaetsklinikum Tuebingen, Department fuer Frauengesundheit, Calwerstrasse 7, 72076 Tuebingen, Germany. IN - Kommoss, F. Institut fuer Pathologie, Referenzzentrum fuer Gynaekopathologie, A2,2, 68159 Mannheim, Germany. IN - Hauptmann, S. 1] Universitaetsklinikum Halle (Saale), Universitaetsklinik und Poliklinik fuer Gynaekologie, Ernst-Grube-Str. 40, 06120 Halle (Saale), Germany [2] Institut fuer Pathologie Trier-Dueren-Duesseldorf, Roonstrasse 30, 52351 Dueren, Germany. IN - du Bois, A. Kliniken Essen-Mitte, Klinik fuer Gynaekologische Onkologie, Henricistrasse 92, 45136 Essen, Germany. TI - Surgical staging and prognosis in serous borderline ovarian tumours (BOT): a subanalysis of the AGO ROBOT study. SO - British Journal of Cancer. 112(4):660-6, 2015 Feb 17 AS - Br J Cancer. 112(4):660-6, 2015 Feb 17 NJ - British journal of cancer PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - av4, 0370635 IO - Br. J. Cancer PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333495 SB - Index Medicus CP - England MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - *Cystadenoma, Serous/di [Diagnosis] MH - Cystadenoma, Serous/ep [Epidemiology] MH - *Cystadenoma, Serous/pa [Pathology] MH - Cystadenoma, Serous/su [Surgery] MH - Female MH - *Gynecologic Surgical Procedures MH - Humans MH - Middle Aged MH - Neoplasm Recurrence, Local/ep [Epidemiology] MH - Neoplasm Recurrence, Local/pa [Pathology] MH - Neoplasm Staging MH - *Ovarian Neoplasms/di [Diagnosis] MH - Ovarian Neoplasms/ep [Epidemiology] MH - *Ovarian Neoplasms/pa [Pathology] MH - Ovarian Neoplasms/su [Surgery] MH - Prognosis MH - Young Adult AB - BACKGROUND: Incomplete surgical staging is a negative prognostic factor for patients with borderline ovarian tumours (BOT). However, little is known about the prognostic impact of each individual staging procedure. AB - METHODS: Clinical parameters of 950 patients with BOT (confirmed by central reference pathology) treated between 1998 and 2008 at 24 German AGO centres were analysed. In 559 patients with serous BOT and adequate ovarian surgery, further recommended staging procedures (omentectomy, peritoneal biopsies, cytology) were evaluated applying Cox regression models with respect to progression-free survival (PFS). AB - RESULTS: For patients with one missing staging procedure, the hazard ratio (HR) for recurrence was 1.25 (95%-CI 0.66-2.39; P=0.497). This risk increased with each additional procedure skipped reaching statistical significance in case of two (HR 1.95; 95%-CI 1.06-3.58; P=0.031) and three missing steps (HR 2.37; 95%-CI 1.22-4.64; P=0.011). The most crucial procedure was omentectomy which retained a statistically significant impact on PFS in multiple analysis (HR 1.91; 95%-CI 1.15-3.19; P=0.013) adjusting for previously established prognostic factors as FIGO stage, tumour residuals, and fertility preservation. AB - CONCLUSION: Individual surgical staging procedures contribute to the prognosis for patients with serous BOT. In this analysis, recurrence risk increased with each skipped surgical step. This should be considered when re-staging procedures following incomplete primary surgery are discussed. ES - 1532-1827 IL - 0007-0920 DI - bjc2014648 DO - https://dx.doi.org/10.1038/bjc.2014.648 PT - Clinical Trial PT - Journal Article PT - Multicenter Study ID - 25562434 [pubmed] ID - bjc2014648 [pii] ID - 10.1038/bjc.2014.648 [doi] ID - PMC4333495 [pmc] PP - ppublish PH - 2014/09/01 [received] PH - 2014/11/27 [revised] PH - 2014/12/06 [accepted] LG - English EP - 20150106 DP - 2015 Feb 17 DC - 20150218 EZ - 2015/01/07 06:00 DA - 2015/05/02 06:00 DT - 2015/01/07 06:00 YR - 2015 ED - 20150501 RD - 20160217 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25562434 <204. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25778333 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Orsolya M AU - Attila-Zoltan M AU - Gherman V AU - Zaharie F AU - Bolboaca S AU - Chira C AU - Bodolea C AU - Tomuleasa C AU - Irimie A AU - Coman I AU - Ionescu D FA - Orsolya, Mihaly FA - Attila-Zoltan, Mihaly FA - Gherman, Vitalie FA - Zaharie, Florin FA - Bolboaca, Sorana FA - Chira, Cipriana FA - Bodolea, Constantin FA - Tomuleasa, Ciprian FA - Irimie, Alexandru FA - Coman, Ioan FA - Ionescu, Daniela IN - Orsolya, Mihaly. Department of Anesthesiology and Intensive Care Unit, Clinical Emergency County Hospital, Cluj-Napoca, Romania. TI - The effect of anaesthetic management on neutrophil gelatinase associated lipocalin (NGAL) levels after robotic surgical oncology. SO - Journal of B.U.On.. 20(1):317-24, 2015 Jan-Feb AS - J. Balk. Union Oncol.. 20(1):317-24, 2015 Jan-Feb NJ - Journal of B.U.ON. : official journal of the Balkan Union of Oncology PI - Journal available in: Print PI - Citation processed from: Print JC - 100883428 IO - J BUON SB - Index Medicus CP - Greece MH - *Acute Kidney Injury/bl [Blood] MH - Acute Kidney Injury/di [Diagnosis] MH - Acute Kidney Injury/ep [Epidemiology] MH - Acute-Phase Proteins MH - Aged MH - Anesthesia, Epidural/ae [Adverse Effects] MH - *Anesthesia, Epidural MH - Anesthesia, General/ae [Adverse Effects] MH - *Anesthesia, General MH - Biomarkers/bl [Blood] MH - Creatinine/bl [Blood] MH - Female MH - Gynecologic Surgical Procedures/ae [Adverse Effects] MH - *Gynecologic Surgical Procedures MH - Humans MH - Incidence MH - Lipocalin-2 MH - *Lipocalins/bl [Blood] MH - Longitudinal Studies MH - Male MH - Middle Aged MH - Prospective Studies MH - *Proto-Oncogene Proteins/bl [Blood] MH - *Robotics MH - Romania/ep [Epidemiology] MH - Surgery, Computer-Assisted/ae [Adverse Effects] MH - *Surgery, Computer-Assisted MH - Time Factors MH - Treatment Outcome MH - Urogenital Neoplasms/bl [Blood] MH - Urogenital Neoplasms/pa [Pathology] MH - *Urogenital Neoplasms/su [Surgery] MH - Urologic Surgical Procedures/ae [Adverse Effects] MH - *Urologic Surgical Procedures AB - PURPOSE: The main objective of this study was to compare the effect of two anaesthetic techniques (general vs combined) on plasma levels of NGAL (Neutrophil Gelatinase Associated Lipocalin) after robotic urogenital oncosurgery. The secondary objective was to correlate NGAL levels with the incidence of acute kidney injury (AKI). AB - METHODS: This was a longitudinal prospective study. Forty patients were included and randomized in 2 groups: group C (N=16 cases; combined general-epidural anesthesia) and group G (N=24 cases; control group with general anesthesia). Demographic data, Charlson Comorbidity Index, Apache II, SOFA and ASA scores were similar in both groups. Serum creatinine was determined preoperatively and every 24 hrs for 4 postoperative days to identify AKI according to RIFLE and AKIN criteria. Serum NGAL was determined at 6 and 12 hrs after induction of anesthesia. AB - RESULTS: Serum creatinine increased at 24 hrs postoperatively in both groups as compared to baseline, but significant changes were registered only in the G group (p(control) = 0.004). Serum NGAL increased significantly in both groups as compared with baseline levels (pcase=0.0034 vs p(control)=0.0001). The incidence of AKI was 12.50% (95% CI 0.4-34) in the C group and 37.50% (95% CI 17-58) in the G group (p=0.0909), respectively. AB - CONCLUSION: Impaired renal function and AKI occurred in robot-assisted laparoscopic urogenital oncosurgery under both general and combined anaesthesia. The incidence of AKI was lower in patients undergoing combined anesthesia compared to general anaesthesia after robotic urogenital oncosurgery but the difference did not reach statistical significance. However, plasma levels of NGAL were significantly increased at 6 and 12 hrs in the general anaesthesia group as compared with combined anaesthesia. NGAL may be a better marker in detecting postoperative acute kidney injury. Further studies are needed. RN - 0 (Acute-Phase Proteins) RN - 0 (Biomarkers) RN - 0 (LCN2 protein, human) RN - 0 (Lipocalin-2) RN - 0 (Lipocalins) RN - 0 (Proto-Oncogene Proteins) RN - AYI8EX34EU (Creatinine) IS - 1107-0625 IL - 1107-0625 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 25778333 [pubmed] PP - ppublish LG - English DP - 2015 Jan-Feb DC - 20150317 EZ - 2015/03/18 06:00 DA - 2015/05/01 06:00 DT - 2015/03/18 06:00 YR - 2015 ED - 20150430 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25778333 <205. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25674758 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Park JS AU - Chung JW AU - Kim NK AU - Cho MS AU - Kang CM AU - Choi SB AU - Kim DW FA - Park, Jee Soo FA - Chung, Jai Won FA - Kim, Nam Kyu FA - Cho, Min Soo FA - Kang, Chang Moo FA - Choi, Soo Beom FA - Kim, Deok Won IN - Park, Jee Soo. From the Department of Medical Engineering (JSP, JWC, SBC, DWK); Department of Medicine (JSP); Graduate Program in Biomedical Engineering (JWC, DWK); Brain Korea 21 PLUS Project for Medical Science (SBC); the Colon and Rectal Surgery, Department of Surgery (NKK, MSC); and the Hepatobiliary and Pancreatic Surgery, Department of Surgery (CMK), Yonsei University College of Medicine, Seoul, Korea. TI - Exposure of surgeons to extremely low-frequency magnetic fields during laparoscopic and robotic surgeries. SO - Medicine. 94(6):e539, 2015 Feb AS - Medicine (Baltimore). 94(6):e539, 2015 Feb NJ - Medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - mny, 2985248r IO - Medicine (Baltimore) PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602749 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Humans MH - *Laparoscopy MH - *Magnetic Fields MH - *Occupational Exposure MH - *Robotic Surgical Procedures MH - *Surgeons AB - The development of new medical electronic devices and equipment has increased the use of electrical apparatuses in surgery. Many studies have reported the association of long-term exposure to extremely low-frequency magnetic fields (ELF-MFs) with diseases or cancer. Robotic surgery has emerged as an alternative tool to overcome the disadvantages of conventional laparoscopic surgery. However, there has been no report regarding how much ELF-MF surgeons are exposed to during laparoscopic and robotic surgeries. In this observational study, we aimed to measure and compare the ELF-MFs that surgeons are exposed to during laparoscopic and robotic surgery.The intensities of the ELF-MFs surgeons are exposed to were measured every 4 seconds for 20 cases of laparoscopic surgery and 20 cases of robotic surgery using portable ELF-MF measuring devices with logging capability.The mean ELF-MF exposures were 0.6 +/- 0.1 mG for laparoscopic surgeries and 0.3 +/- 0.0 mG for robotic surgeries (significantly lower with P < 0.001 by Mann-Whitney U test).Our results show that the ELF-MF exposure levels of surgeons in both robotic and conventional laparoscopic surgery were lower than 2 mG, which is the most stringent level considered safe in many studies. However, we should not overlook the effects of long-term ELF-MF exposure during many surgeries in the course of a surgeon's career. ES - 1536-5964 IL - 0025-7974 DI - 00005792-201502020-00031 DO - https://dx.doi.org/10.1097/MD.0000000000000539 PT - Journal Article PT - Observational Study PT - Research Support, Non-U.S. Gov't ID - 25674758 [pubmed] ID - 10.1097/MD.0000000000000539 [doi] ID - 00005792-201502020-00031 [pii] ID - PMC4602749 [pmc] PP - ppublish LG - English DP - 2015 Feb DC - 20150214 EZ - 2015/02/13 06:00 DA - 2015/04/24 06:00 DT - 2015/02/13 06:00 YR - 2015 ED - 20150423 RD - 20151028 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25674758 <206. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25060020 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tu S AU - Barbato E AU - Koszegi Z AU - Yang J AU - Sun Z AU - Holm NR AU - Tar B AU - Li Y AU - Rusinaru D AU - Wijns W AU - Reiber JH FA - Tu, Shengxian FA - Barbato, Emanuele FA - Koszegi, Zsolt FA - Yang, Junqing FA - Sun, Zhonghua FA - Holm, Niels R FA - Tar, Balazs FA - Li, Yingguang FA - Rusinaru, Dan FA - Wijns, William FA - Reiber, Johan H C IN - Tu, Shengxian. Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: S.T.Tu@lumc.nl. IN - Barbato, Emanuele. Cardiovascular Center Aalst, Onze-Lieve-Vrouwziekenhuis (OLV) Hospital, Aalst, Belgium. IN - Koszegi, Zsolt. Invasive Cardiology Laboratory, Josa Andras Teaching Hospital, Nyiregyhaza, Hungary. IN - Yang, Junqing. Department of Cardiology, Guangdong General Hospital, Guangzhou, China. IN - Sun, Zhonghua. Department of Cardiology, TEDA International Cardiovascular Hospital, Tianjin, China. IN - Holm, Niels R. Department of Cardiology, Aarhus University Hospital, Skejby, Denmark. IN - Tar, Balazs. Invasive Cardiology Laboratory, Josa Andras Teaching Hospital, Nyiregyhaza, Hungary. IN - Li, Yingguang. Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands. IN - Rusinaru, Dan. Cardiovascular Center Aalst, Onze-Lieve-Vrouwziekenhuis (OLV) Hospital, Aalst, Belgium. IN - Wijns, William. Cardiovascular Center Aalst, Onze-Lieve-Vrouwziekenhuis (OLV) Hospital, Aalst, Belgium. IN - Reiber, Johan H C. Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands. TI - Fractional flow reserve calculation from 3-dimensional quantitative coronary angiography and TIMI frame count: a fast computer model to quantify the functional significance of moderately obstructed coronary arteries. CM - Comment in: JACC Cardiovasc Interv. 2014 Jul;7(7):778-80; PMID: 25060021 SO - Jacc: Cardiovascular Interventions. 7(7):768-77, 2014 Jul AS - JACC Cardiovasc Interv. 7(7):768-77, 2014 Jul NJ - JACC. Cardiovascular interventions PI - Journal available in: Print PI - Citation processed from: Internet JC - 101467004 IO - JACC Cardiovasc Interv SB - Index Medicus CP - United States MH - Aged MH - Area Under Curve MH - Cardiac Catheterization MH - China MH - Computer Simulation MH - *Coronary Angiography/mt [Methods] MH - Coronary Angiography/st [Standards] MH - *Coronary Stenosis/dg [Diagnostic Imaging] MH - Coronary Stenosis/pp [Physiopathology] MH - *Coronary Vessels/dg [Diagnostic Imaging] MH - Coronary Vessels/pp [Physiopathology] MH - False Negative Reactions MH - False Positive Reactions MH - Female MH - *Fractional Flow Reserve, Myocardial MH - Humans MH - Hungary MH - Hyperemia/dg [Diagnostic Imaging] MH - Hyperemia/pp [Physiopathology] MH - Imaging, Three-Dimensional/st [Standards] MH - *Imaging, Three-Dimensional MH - Male MH - Middle Aged MH - Models, Cardiovascular MH - *Myocardial Perfusion Imaging/mt [Methods] MH - Myocardial Perfusion Imaging/st [Standards] MH - Predictive Value of Tests MH - Prognosis MH - ROC Curve MH - Radiographic Image Interpretation, Computer-Assisted/st [Standards] MH - *Radiographic Image Interpretation, Computer-Assisted MH - Reference Standards MH - Retrospective Studies MH - Severity of Illness Index MH - Time Factors MH - *Tomography, X-Ray Computed/mt [Methods] MH - Tomography, X-Ray Computed/st [Standards] KW - cardiovascular physiology; computational fluid dynamics; fractional flow reserve; quantitative coronary angiography AB - OBJECTIVES: This study sought to present a novel computer model for fast computation of myocardial fractional flow reserve (FFR) and to evaluate it in patients with intermediate coronary stenoses. AB - BACKGROUND: FFR is an indispensable tool to identify individual coronary stenoses causing ischemia. Calculation of FFR from x-ray angiographic data may increase the utility of FFR assessment. AB - METHODS: Consecutive patients with intermediate coronary stenoses undergoing pressure wire-based FFR measurements were analyzed by a core laboratory. Three-dimensional quantitative coronary angiography (QCA) was performed and the mean volumetric flow rate at hyperemia was calculated using TIMI (Thrombolysis In Myocardial Infarction) frame count combined with 3-dimensional QCA. Computational fluid dynamics was applied subsequently with a novel strategy for the computation of FFR. Diagnostic performance of the computed FFR (FFRQCA) was assessed using wire-based FFR as reference standard. AB - RESULTS: Computation of FFRQCA was performed on 77 vessels in 68 patients. Average diameter stenosis was 46.6 +/- 7.3%. FFRQCA correlated well with FFR (r = 0.81, p < 0.001), with a mean difference of 0.00 +/- 0.06 (p = 0.541). Applying the FFR cutoff value of <0.8 to FFRQCA resulted in 18 true positives, 50 true negatives, 4 false positives, and 5 false negatives. The area under the receiver-operating characteristic curve was 0.93 for FFRQCA, 0.73 for minimum lumen area, and 0.65 for percent diameter stenosis. AB - CONCLUSIONS: Computation of FFRQCA is a novel method that allows the assessment of the functional significance of intermediate stenosis. It may emerge as a safe, efficient, and cost-reducing tool for evaluation of coronary stenosis severity during diagnostic angiography. AB - Copyright © 2014 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. ES - 1876-7605 IL - 1936-8798 DI - S1936-8798(14)00791-2 DO - https://dx.doi.org/10.1016/j.jcin.2014.03.004 PT - Evaluation Studies PT - Journal Article PT - Multicenter Study PT - Observational Study PT - Research Support, Non-U.S. Gov't ID - 25060020 [pubmed] ID - S1936-8798(14)00791-2 [pii] ID - 10.1016/j.jcin.2014.03.004 [doi] PP - ppublish PH - 2014/02/28 [received] PH - 2014/03/21 [revised] PH - 2014/03/27 [accepted] LG - English DP - 2014 Jul DC - 20140725 EZ - 2014/07/26 06:00 DA - 2015/04/14 06:00 DT - 2014/07/26 06:00 YR - 2014 ED - 20150413 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25060020 <207. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25108142 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Zechmeister JR AU - Pua TL AU - Boyd LR AU - Blank SV AU - Curtin JP AU - Pothuri B FA - Zechmeister, Jenna R FA - Pua, Tarah L FA - Boyd, Leslie R FA - Blank, Stephanie V FA - Curtin, John P FA - Pothuri, Bhavana IN - Zechmeister, Jenna R. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, NYU Langone Medical Center, New York, NY. IN - Pua, Tarah L. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, NYU Langone Medical Center, New York, NY. IN - Boyd, Leslie R. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, NYU Langone Medical Center, New York, NY. IN - Blank, Stephanie V. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, NYU Langone Medical Center, New York, NY. IN - Curtin, John P. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, NYU Langone Medical Center, New York, NY. IN - Pothuri, Bhavana. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, NYU Langone Medical Center, New York, NY. Electronic address: Bhavana.Pothuri@nyumc.org. TI - A prospective comparison of postoperative pain and quality of life in robotic assisted vs conventional laparoscopic gynecologic surgery. SO - American Journal of Obstetrics & Gynecology. 212(2):194.e1-7, 2015 Feb AS - Am J Obstet Gynecol. 212(2):194.e1-7, 2015 Feb NJ - American journal of obstetrics and gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 3ni, 0370476 IO - Am. J. Obstet. Gynecol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Female MH - *Genital Diseases, Female/su [Surgery] MH - *Gynecologic Surgical Procedures/mt [Methods] MH - Humans MH - *Laparoscopy/mt [Methods] MH - Length of Stay/sn [Statistics & Numerical Data] MH - Middle Aged MH - Operative Time MH - Pain Measurement MH - Pain, Postoperative/dt [Drug Therapy] MH - *Pain, Postoperative/pc [Prevention & Control] MH - Prospective Studies MH - *Quality of Life MH - *Robotic Surgical Procedures/mt [Methods] KW - laparoscopic surgery; postoperative pain; quality of life; robotic surgery AB - OBJECTIVE: We sought to compare robotic vs laparoscopic surgery in regards to patient reported postoperative pain and quality of life. AB - STUDY DESIGN: This was a prospective study of patients who presented for treatment of a new gynecologic disease requiring minimally invasive surgical intervention. All subjects were asked to take the validated Brief Pain Inventory-Short Form at 3 time points to assess pain and its effect on quality of life. Statistical analyses were performed using Pearson x(2) and Student's t test. AB - RESULTS: One hundred eleven were included in the analysis of which 56 patients underwent robotic assisted surgery and 55 patients underwent laparoscopic surgery. There was no difference in postoperative pain between conventional laparoscopy and robotic assisted surgery for gynecologic procedures. There was a statistically significant difference found at the delayed postoperative period when evaluating interference of sleep, favoring laparoscopy (ROB 2.0 vs LSC 1.0; P = .03). There were no differences found between the robotic and laparoscopic groups of patients receiving narcotics (56 vs 53, P = .24, respectively), route of administration of narcotics (47 vs 45, P > .99, respectively), or administration of nonsteroidal antiinflammatory medications (27 vs 21, P = .33, respectively). AB - CONCLUSION: Our results demonstrate no difference in postoperative pain between conventional laparoscopy and robotic assisted surgery for gynecologic procedures. Furthermore, pain did not appear to interfere consistently with any daily activity of living. Interference of sleep needs to be further evaluated after controlling for bilateral salpingo-oophorectomy. AB - Copyright © 2015 Elsevier Inc. All rights reserved. ES - 1097-6868 IL - 0002-9378 DI - S0002-9378(14)00815-1 DO - https://dx.doi.org/10.1016/j.ajog.2014.08.003 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 25108142 [pubmed] ID - S0002-9378(14)00815-1 [pii] ID - 10.1016/j.ajog.2014.08.003 [doi] PP - ppublish PH - 2014/04/14 [received] PH - 2014/07/10 [revised] PH - 2014/08/04 [accepted] LG - English EP - 20140806 DP - 2015 Feb DC - 20150130 EZ - 2014/08/10 06:00 DA - 2015/04/09 06:00 DT - 2014/08/12 06:00 YR - 2015 ED - 20150408 RD - 20150130 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25108142 <208. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25523669 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Cadeddu JA FA - Cadeddu, Jeffrey A TI - Re: One- vs 4-week stent placement after laparoscopic and robot-assisted pyeloplasty: results of a prospective randomised single-centre study. CM - Comment on: BJU Int. 2014 Jun;113(6):931-5; PMID: 24472002 SO - Journal of Urology. 193(1):171-2, 2015 Jan AS - J Urol. 193(1):171-2, 2015 Jan NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Female MH - Humans MH - *Kidney Pelvis/su [Surgery] MH - *Laparoscopy MH - Male MH - *Robotics MH - *Stents MH - *Ureteral Obstruction/su [Surgery] ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(14)04631-X DO - https://dx.doi.org/10.1016/j.juro.2014.10.013 PT - Comment PT - Editorial ID - 25523669 [pubmed] ID - S0022-5347(14)04631-X [pii] ID - 10.1016/j.juro.2014.10.013 [doi] PP - ppublish LG - English EP - 20141012 DP - 2015 Jan DC - 20141219 EZ - 2014/12/20 06:00 DA - 2015/04/04 06:00 DT - 2014/12/20 06:00 YR - 2015 ED - 20150402 RD - 20141219 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25523669 <209. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25150644 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Mohareri O AU - Ischia J AU - Black PC AU - Schneider C AU - Lobo J AU - Goldenberg L AU - Salcudean SE FA - Mohareri, Omid FA - Ischia, Joseph FA - Black, Peter C FA - Schneider, Caitlin FA - Lobo, Julio FA - Goldenberg, Larry FA - Salcudean, Septimiu E IN - Mohareri, Omid. Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, British Columbia, Canada. IN - Ischia, Joseph. University of Melbourne, Melbourne, Australia. IN - Black, Peter C. Department of Urological Sciences, University of British Columbia, Vancouver, British Columbia, Canada. IN - Schneider, Caitlin. Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, British Columbia, Canada. IN - Lobo, Julio. Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, British Columbia, Canada. IN - Goldenberg, Larry. Department of Urological Sciences, University of British Columbia, Vancouver, British Columbia, Canada. IN - Salcudean, Septimiu E. Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, British Columbia, Canada. TI - Intraoperative registered transrectal ultrasound guidance for robot-assisted laparoscopic radical prostatectomy. SO - Journal of Urology. 193(1):302-12, 2015 Jan AS - J Urol. 193(1):302-12, 2015 Jan NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Humans MH - *Intraoperative Care MH - *Laparoscopy MH - Male MH - Middle Aged MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/dg [Diagnostic Imaging] MH - *Prostatic Neoplasms/su [Surgery] MH - Rectum MH - *Robotic Surgical Procedures MH - *Surgery, Computer-Assisted MH - Ultrasonography, Interventional/mt [Methods] MH - *Ultrasonography, Interventional KW - laparoscopy; prostatectomy; prostatic neoplasms; robotics; ultrasonography AB - PURPOSE: To provide unencumbered real-time ultrasound image guidance during robot-assisted laparoscopic radical prostatectomy, we developed a robotic transrectal ultrasound system that tracks the da Vinci Surgical System instruments. We describe our initial clinical experience with this system. AB - MATERIALS AND METHODS: After an evaluation in a canine model, 20 patients were enrolled in the study. During each procedure the transrectal ultrasound transducer was manually positioned using a brachytherapy stabilizer to provide good imaging of the prostate. Then the transrectal ultrasound was registered to the da Vinci robot by a previously validated procedure. Finally, automatic rotation of the transrectal ultrasound was enabled such that the transrectal ultrasound imaging plane safely tracked the tip of the da Vinci instrument controlled by the surgeon, while real-time transrectal ultrasound images were relayed to the surgeon at the da Vinci console. Tracking was activated during all critical stages of the surgery. AB - RESULTS: The transrectal ultrasound robot was easy to set up and use, adding 7 minutes (range 5 to 14) to the procedure. It did not require an assistant or additional control devices. Qualitative feedback was acquired from the surgeons, who found transrectal ultrasound useful in identifying the urethra while passing the dorsal venous complex suture, defining the prostate-bladder interface during bladder neck dissection, identifying the seminal vesicles and their location with respect to the rectal wall, and identifying the distal prostate boundary at the apex. AB - CONCLUSIONS: Real-time, registered robotic transrectal ultrasound guidance with automatic instrument tracking during robot-assisted laparoscopic radical prostatectomy is feasible and potentially useful. The results justify further studies to establish whether the approach can improve procedure outcomes. AB - Copyright © 2015 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(14)04262-1 DO - https://dx.doi.org/10.1016/j.juro.2014.05.124 PT - Clinical Trial, Phase I PT - Clinical Trial, Phase II PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 25150644 [pubmed] ID - S0022-5347(14)04262-1 [pii] ID - 10.1016/j.juro.2014.05.124 [doi] PP - ppublish PH - 2014/05/21 [accepted] GI - Organization: *Canadian Institutes of Health Research* Country: Canada LG - English EP - 20140821 DP - 2015 Jan DC - 20141219 EZ - 2014/08/25 06:00 DA - 2015/04/04 06:00 DT - 2014/08/26 06:00 YR - 2015 ED - 20150402 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25150644 <210. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24913254 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kim JC AU - Kwak JY AU - Yoon YS AU - Park IJ AU - Kim CW FA - Kim, Jin C FA - Kwak, Jae Y FA - Yoon, Yong S FA - Park, In J FA - Kim, Chan W IN - Kim, Jin C. Department of Surgery, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, Seoul, South Korea, jckim@amc.seoul.kr. TI - A comparison of the technical and oncologic validity between robot-assisted and conventional open abdominoperineal resection. SO - International Journal of Colorectal Disease. 29(8):961-9, 2014 Aug AS - Int J Colorectal Dis. 29(8):961-9, 2014 Aug NJ - International journal of colorectal disease PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - itf, 8607899 IO - Int J Colorectal Dis SB - Index Medicus CP - Germany MH - Abdomen/pa [Pathology] MH - *Abdomen/su [Surgery] MH - *Digestive System Surgical Procedures/mt [Methods] MH - Female MH - Humans MH - Male MH - Middle Aged MH - Perineum/pa [Pathology] MH - *Perineum/su [Surgery] MH - Postoperative Care MH - *Rectal Neoplasms/su [Surgery] MH - *Robotics/mt [Methods] MH - Treatment Outcome AB - PURPOSE: This study was to ascertain whether a robot-assisted (RA) approach to APR might facilitate a cylindrical APR by enabling a deeper pelvic dissection during an abdominal approach, concurrently comparing the feasibility and short-term oncologic outcomes. AB - METHODS: Forty-eight consecutive patients with lower rectal cancer who had undergone curative APR (21 RA vs. 27 open) were prospectively enrolled. The short-term operative outcomes and oncologic feasibility were evaluated and compared. A levator muscle excision was performed concomitantly with the abdominal procedure in the RA group and with the perineal procedure in the open group. AB - RESULTS: No patients in the RA group experienced intraoperative perforation or required conversion to open APR. Overall, a cylindrical APR was performed in 72 % of patients, and subtotal excision of the levator muscle, i.e., either one or both sides of the puborectalis and pubococcygeus muscles, was more likely in the RA group (P=0.019). A positive CRM was exclusively identified in four open APR patients. The mean number of retrieved lymph nodes was greater in the RA group (20 vs. 16, P=0.035). There was no difference in perineal morbidity between the two groups (P=0.445). AB - CONCLUSIONS: The RA approach facilitates an efficient excision in the pelvic region than open APR during the abdominal procedure. The RA approach also demonstrated a trend toward improved oncologic outcomes with equivalent postoperative morbidities than with the open approach. ES - 1432-1262 IL - 0179-1958 DO - https://dx.doi.org/10.1007/s00384-014-1916-9 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 24913254 [pubmed] ID - 10.1007/s00384-014-1916-9 [doi] PP - ppublish PH - 2014/06/02 [accepted] LG - English EP - 20140610 DP - 2014 Aug DC - 20140717 EZ - 2014/06/11 06:00 DA - 2015/03/31 06:00 DT - 2014/06/11 06:00 YR - 2014 ED - 20150330 RD - 20140717 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24913254 <211. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24612471 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Chowriappa A AU - Raza SJ AU - Fazili A AU - Field E AU - Malito C AU - Samarasekera D AU - Shi Y AU - Ahmed K AU - Wilding G AU - Kaouk J AU - Eun DD AU - Ghazi A AU - Peabody JO AU - Kesavadas T AU - Mohler JL AU - Guru KA FA - Chowriappa, Ashirwad FA - Raza, Syed Johar FA - Fazili, Anees FA - Field, Erinn FA - Malito, Chelsea FA - Samarasekera, Dinesh FA - Shi, Yi FA - Ahmed, Kamran FA - Wilding, Gregory FA - Kaouk, Jihad FA - Eun, Daniel D FA - Ghazi, Ahmed FA - Peabody, James O FA - Kesavadas, Thenkurussi FA - Mohler, James L FA - Guru, Khurshid A IN - Chowriappa, Ashirwad. Roswell Park Cancer Institute, Buffalo, NY, USA; State University of New York, Buffalo, NY, USA. TI - Augmented-reality-based skills training for robot-assisted urethrovesical anastomosis: a multi-institutional randomised controlled trial. SO - BJU International. 115(2):336-45, 2015 Feb AS - BJU Int. 115(2):336-45, 2015 Feb NJ - BJU international PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - dcu, 100886721 IO - BJU Int. SB - Index Medicus CP - England MH - *Anastomosis, Surgical/ed [Education] MH - Anastomosis, Surgical/mt [Methods] MH - Anastomosis, Surgical/st [Standards] MH - *Clinical Competence MH - *Computer Simulation MH - Humans MH - *Laparoscopy/ed [Education] MH - Laparoscopy/mt [Methods] MH - Laparoscopy/st [Standards] MH - *Robotic Surgical Procedures/ed [Education] MH - Robotic Surgical Procedures/mt [Methods] MH - Robotic Surgical Procedures/st [Standards] MH - Surveys and Questionnaires MH - Task Performance and Analysis MH - *Urethra/su [Surgery] KW - anastomosis; augmented reality; robot-assisted; robotic; skills training; urethrovesical anastomosis AB - OBJECTIVE: To validate robot-assisted surgery skills acquisition using an augmented reality (AR)-based module for urethrovesical anastomosis (UVA). AB - METHODS: Participants at three institutions were randomised to a Hands-on Surgical Training (HoST) technology group or a control group. The HoST group was given procedure-based training for UVA within the haptic-enabled AR-based HoST environment. The control group did not receive any training. After completing the task, the control group was offered to cross over to the HoST group (cross-over group). A questionnaire administered after HoST determined the feasibility and acceptability of the technology. Performance of UVA using an inanimate model on the daVinci Surgical System (Intuitive Surgical Inc., Sunnyvale, CA, USA) was assessed using a UVA evaluation score and a Global Evaluative Assessment of Robotic Skills (GEARS) score. Participants completed the National Aeronautics and Space Administration Task Load Index (NASA TLX) questionnaire for cognitive assessment, as outcome measures. A Wilcoxon rank-sum test was used to compare outcomes among the groups (HoST group vs control group and control group vs cross-over group). AB - RESULTS: A total of 52 individuals participated in the study. UVA evaluation scores showed significant differences in needle driving (3.0 vs 2.3; P = 0.042), needle positioning (3.0 vs 2.4; P = 0.033) and suture placement (3.4 vs 2.6; P = 0.014) in the HoST vs the control group. The HoST group obtained significantly higher scores (14.4 vs 11.9; P 0.012) on the GEARS. The NASA TLX indicated lower temporal demand and effort in the HoST group (5.9 vs 9.3; P = 0.001 and 5.8 vs 11.9; P = 0.035, respectively). In all, 70% of participants found that HoST was similar to the real surgical procedure, and 75% believed that HoST could improve confidence for carrying out the real intervention. AB - CONCLUSION: Training in UVA in an AR environment improves technical skill acquisition with minimal cognitive demand. AB - Copyright © 2014 The Authors. BJU International © 2014 BJU International. ES - 1464-410X IL - 1464-4096 DO - https://dx.doi.org/10.1111/bju.12704 PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't PT - Validation Studies ID - 24612471 [pubmed] ID - 10.1111/bju.12704 [doi] PP - ppublish LG - English EP - 20140816 DP - 2015 Feb DC - 20150121 EZ - 2014/03/12 06:00 DA - 2015/03/26 06:00 DT - 2014/03/13 06:00 YR - 2015 ED - 20150325 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24612471 <212. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25530362 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Raza SJ AU - Field E AU - Jay C AU - Eun D AU - Fumo M AU - Hu JC AU - Lee D AU - Mehboob Z AU - Nyquist J AU - Peabody JO AU - Sarle R AU - Stricker H AU - Yang Z AU - Wilding G AU - Mohler JL AU - Guru KA FA - Raza, Syed Johar FA - Field, Erinn FA - Jay, Christopher FA - Eun, Daniel FA - Fumo, Michael FA - Hu, Jim C FA - Lee, David FA - Mehboob, Zayn FA - Nyquist, John FA - Peabody, James O FA - Sarle, Richard FA - Stricker, Hans FA - Yang, Zhengyu FA - Wilding, Gregory FA - Mohler, James L FA - Guru, Khurshid A IN - Raza, Syed Johar. Department of Urology, Roswell Park Cancer Institute, Buffalo, NY. IN - Field, Erinn. Department of Urology, Roswell Park Cancer Institute, Buffalo, NY. IN - Jay, Christopher. Department of Urology, Roswell Park Cancer Institute, Buffalo, NY. IN - Eun, Daniel. Department of Urology, Temple University School of Medicine, Philadelphia, PA. IN - Fumo, Michael. Department of Urology, University of Illinois College of Medicine at Rockford, Rockford, IL. IN - Hu, Jim C. Department of Urology, University of California, Los Angeles, CA. IN - Lee, David. Division of Urology, Penn Presbyterian Medical Center, Philadelphia, PA. IN - Mehboob, Zayn. Department of Urology, Roswell Park Cancer Institute, Buffalo, NY. IN - Nyquist, John. Department of Health Sciences: Pathology and Anatomical Sciences, Medical Illustrations and Graphics, University at Buffalo, Buffalo, NY. IN - Peabody, James O. Vattikuti Urology Institute, Henry Ford Hospital, Detroit, MI. IN - Sarle, Richard. Department of Urology, Wayne State University Medical School, Detroit, MI. IN - Stricker, Hans. Vattikuti Urology Institute, Henry Ford Hospital, Detroit, MI. IN - Yang, Zhengyu. Department of Urology, Roswell Park Cancer Institute, Buffalo, NY. IN - Wilding, Gregory. Department of Urology, Roswell Park Cancer Institute, Buffalo, NY. IN - Mohler, James L. Department of Urology, Roswell Park Cancer Institute, Buffalo, NY. IN - Guru, Khurshid A. Department of Urology, Roswell Park Cancer Institute, Buffalo, NY. Electronic address: Khurshid.guru@roswellpark.org. TI - Surgical competency for urethrovesical anastomosis during robot-assisted radical prostatectomy: development and validation of the robotic anastomosis competency evaluation. SO - Urology. 85(1):27-32, 2015 Jan AS - Urology. 85(1):27-32, 2015 Jan NJ - Urology PI - Journal available in: Print PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Adult MH - Anastomosis, Surgical/st [Standards] MH - *Clinical Competence MH - Female MH - Humans MH - Male MH - Middle Aged MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Robotic Surgical Procedures MH - *Urethra/su [Surgery] MH - *Urinary Bladder/su [Surgery] MH - Urologic Surgical Procedures, Male/mt [Methods] AB - OBJECTIVE: To develop and validate an assessment tool for the performance of urethrovesical anastomosis (UVA). AB - METHODS: A multicenter, prospective, observational study was conducted in 2 phases. Phase 1, development and content validation, used a panel of 5 experienced robotic surgeons to develop a 6-domain scoring system, Robotic Anastomosis Competence Evaluation (RACE), to assess technical skills for performing UVA. Phase 2, construct validation and reliability, used 5 blinded experienced robotic surgeons to rate UVA recordings of expert, advanced beginner, and novice groups. Content validation index was determined to report consensus in phase 1. Phase 2 involved comparison of RACE scores among the 3 groups. Wilcoxon rank-sum tests were used to compare RACE scores. AB - RESULTS: Two rounds of Delphi methodology achieved consensus on language and content of RACE. Eight experts, 10 advanced beginners, and 10 novice robotic surgeons participated in the validation study. The overall score for the expert group (27.3) was higher than that of the advanced beginner (19.5; P = .04) and novice groups (13.6; P = .001). The advanced beginner and novice groups differed in overall scores (P = .03). AB - CONCLUSION: RACE allows evaluation of surgical competence to perform UVA for robot-assisted radical prostatectomy, when using an inanimate model. AB - Copyright © 2015 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(14)01038-3 DO - https://dx.doi.org/10.1016/j.urology.2014.09.017 PT - Journal Article PT - Multicenter Study PT - Observational Study PT - Validation Studies ID - 25530362 [pubmed] ID - S0090-4295(14)01038-3 [pii] ID - 10.1016/j.urology.2014.09.017 [doi] PP - ppublish PH - 2014/06/10 [received] PH - 2014/08/24 [revised] PH - 2014/09/16 [accepted] LG - English DP - 2015 Jan DC - 20141222 EZ - 2014/12/23 06:00 DA - 2015/02/24 06:00 DT - 2014/12/23 06:00 YR - 2015 ED - 20150223 RD - 20141222 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25530362 <213. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24005955 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tokunaga M AU - Sugisawa N AU - Kondo J AU - Tanizawa Y AU - Bando E AU - Kawamura T AU - Terashima M FA - Tokunaga, Masanori FA - Sugisawa, Norihiko FA - Kondo, Junya FA - Tanizawa, Yutaka FA - Bando, Etsuro FA - Kawamura, Taiichi FA - Terashima, Masanori IN - Tokunaga, Masanori. Division of Gastric Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan. TI - Early phase II study of robot-assisted distal gastrectomy with nodal dissection for clinical stage IA gastric cancer. CM - Comment in: Gastric Cancer. 2014;17(3):399-401; PMID: 24078199 SO - Gastric Cancer. 17(3):542-7, 2014 AS - Gastric Cancer. 17(3):542-7, 2014 NJ - Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 100886238 IO - Gastric Cancer SB - Index Medicus CP - Japan MH - Aged MH - Aged, 80 and over MH - Feasibility Studies MH - Female MH - Gastrectomy/ae [Adverse Effects] MH - *Gastrectomy/mt [Methods] MH - Humans MH - Incidence MH - *Lymph Node Excision/mt [Methods] MH - Male MH - Middle Aged MH - Neoplasm Staging MH - Postoperative Complications/ep [Epidemiology] MH - Prospective Studies MH - *Robotics MH - Stomach Neoplasms/pa [Pathology] MH - *Stomach Neoplasms/su [Surgery] MH - Survival Analysis AB - BACKGROUND: Robot-assisted distal gastrectomy (RADG) is increasingly performed in Japan and Korea and is thought to have many advantages over laparoscopic gastrectomy. However, a prospective study investigating the safety of RADG has never been reported. The present study evaluated the safety of RADG with nodal dissection for clinical stage IA gastric cancer. AB - METHODS: This single-center, prospective phase II study included patients with clinical stage IA gastric cancer located within the lower two-thirds of the stomach. The primary endpoint was the incidence of postoperative intraabdominal infectious complications including anastomotic leakage, pancreas-related infection, and intraabdominal abscess. The secondary endpoints included all in-hospital adverse events, RADG completion rate, and survival outcome. AB - RESULTS: From May 2012 to November 2012, 18 eligible patients were enrolled for this study. The incidence of intraabdominal infectious complication was 0 % (90 % CI, 0-12.0 %). The overall incidence of in-hospital adverse events was 22.2 % (90 % CI, 8.0-43.9 %). No patient required conversion to laparoscopic or open gastrectomy; thus, the RADG completion rate was 100 %. AB - CONCLUSIONS: This early phase II study suggested that RADG might be a safe and feasible procedure for stage IA gastric cancer, providing experienced surgeons perform the surgery. This conclusion should be clarified in subsequent late phase II studies with a larger sample size. ES - 1436-3305 IL - 1436-3291 DO - https://dx.doi.org/10.1007/s10120-013-0293-3 PT - Clinical Trial, Phase II PT - Journal Article ID - 24005955 [pubmed] ID - 10.1007/s10120-013-0293-3 [doi] PP - ppublish PH - 2013/03/13 [received] PH - 2013/08/04 [accepted] LG - English EP - 20130905 DP - 2014 DC - 20140626 EZ - 2013/09/06 06:00 DA - 2015/02/24 06:00 DT - 2013/09/06 06:00 YR - 2014 ED - 20150220 RD - 20160512 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24005955 <214. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24440236 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Prasad SM AU - Large MC AU - Patel AR AU - Famakinwa O AU - Galocy RM AU - Karrison T AU - Shalhav AL AU - Zagaja GP FA - Prasad, Sandip M FA - Large, Michael C FA - Patel, Amit R FA - Famakinwa, Olufenwa FA - Galocy, R Matthew FA - Karrison, Theodore FA - Shalhav, Arieh L FA - Zagaja, Gregory P IN - Prasad, Sandip M. Department of Urology, Medical University of South Carolina, Charleston, South Carolina. Electronic address: prasads@musc.edu. IN - Large, Michael C. Section of Urology, University of Chicago Hospitals, Chicago, Illinois. IN - Patel, Amit R. Department of Urology, DuPage Medical Group, Downers Grove, Illinois. IN - Famakinwa, Olufenwa. Section of Urology, University of Chicago Hospitals, Chicago, Illinois. IN - Galocy, R Matthew. Section of Urology, University of Chicago Hospitals, Chicago, Illinois. IN - Karrison, Theodore. Department of Health Studies, University of Chicago Hospitals, Chicago, Illinois. IN - Shalhav, Arieh L. Section of Urology, University of Chicago Hospitals, Chicago, Illinois. IN - Zagaja, Gregory P. Section of Urology, University of Chicago Hospitals, Chicago, Illinois. TI - Early removal of urethral catheter with suprapubic tube drainage versus urethral catheter drainage alone after robot-assisted laparoscopic radical prostatectomy. CM - Comment in: J Urol. 2014 Jul;192(1):95; discussion 95-6; PMID: 24721438 SO - Journal of Urology. 192(1):89-95, 2014 Jul AS - J Urol. 192(1):89-95, 2014 Jul NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - *Device Removal MH - *Drainage/is [Instrumentation] MH - Humans MH - *Laparoscopy MH - Male MH - Middle Aged MH - Pain, Postoperative/ep [Epidemiology] MH - Pain, Postoperative/pc [Prevention & Control] MH - Postoperative Care MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotic Surgical Procedures MH - Time Factors MH - *Urinary Catheterization/is [Instrumentation] MH - *Urinary Catheterization/mt [Methods] MH - *Urinary Catheters KW - cystostomy; pain; prostatectomy; urethra; urinary catheterization AB - PURPOSE: Retrospective single institution data suggest that postoperative pain after robot-assisted laparoscopic radical prostatectomy is decreased by early removal of the urethral catheter with suprapubic tube drainage. In a randomized patient population we determined whether suprapubic tube drainage with early urethral catheter removal would improve postoperative pain compared with urethral catheter drainage alone. AB - MATERIALS AND METHODS: Men with a body mass index of less than 40 kg/m(2) who had newly diagnosed prostate cancer and elected robot-assisted laparoscopic radical prostatectomy were included in analysis. Block randomization by surgeon was used and randomization assignment was done after completing the urethrovesical anastomosis. In patients assigned to suprapubic tube drainage the urethral catheter was removed on postoperative day 1 and all catheters were removed on postoperative day 7. Visual analog pain scale and satisfaction questionnaires were administered on postoperative days 0, 1 and 7. AB - RESULTS: A total of 29 patients were randomized to the urethral catheter vs 29 to the suprapubic tube plus early urethral catheter removal at the time of interim futility analysis. Mean visual analog pain scale scores did not differ between the groups at any time point and a similar percent of patients cited the catheter as the greatest bother with nonsignificant differences in treatment related satisfaction. Complications during postoperative week 1 did not vary between the groups. Based on interim results the trial was terminated due to lack of effect. AB - CONCLUSIONS: Patients randomized to suprapubic tube vs urethral catheter drainage for the week after prostatectomy had similar pain, catheter related bother and treatment related satisfaction in the perioperative period. We no longer routinely offer suprapubic tube drainage with early urethral catheter removal at our institution. AB - Copyright © 2014 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(14)00015-9 DO - https://dx.doi.org/10.1016/j.juro.2014.01.004 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 24440236 [pubmed] ID - S0022-5347(14)00015-9 [pii] ID - 10.1016/j.juro.2014.01.004 [doi] PP - ppublish PH - 2014/01/06 [accepted] LG - English EP - 20140115 DP - 2014 Jul DC - 20141205 EZ - 2014/01/21 06:00 DA - 2015/02/11 06:00 DT - 2014/01/21 06:00 YR - 2014 ED - 20150210 RD - 20150326 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24440236 <215. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25260445 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sandberg JM AU - Krane LS AU - Hemal AK FA - Sandberg, Jason M FA - Krane, Louis Spencer FA - Hemal, Ashok K IN - Sandberg, Jason M. Department of Urology, Wake Forest University School of Medicine, Winston-Salem, NC. IN - Krane, Louis Spencer. Department of Urology, Wake Forest University School of Medicine, Winston-Salem, NC. IN - Hemal, Ashok K. Department of Urology, Wake Forest University School of Medicine, Winston-Salem, NC. Electronic address: ahemal@wakehealth.edu. TI - A nonrandomized prospective comparison of robotic-assisted partial nephrectomy in the elderly to a younger cohort: an analysis of 339 patients with intermediate-term follow-up. CM - Comment in: J Urol. 2016 Feb;195(2):299; PMID: 26852968 SO - Urology. 84(4):838-43, 2014 Oct AS - Urology. 84(4):838-43, 2014 Oct NJ - Urology PI - Journal available in: Print PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Adolescent MH - Adult MH - Age Factors MH - Aged MH - Aged, 80 and over MH - Child MH - Female MH - Follow-Up Studies MH - Humans MH - *Kidney Neoplasms/su [Surgery] MH - Male MH - Middle Aged MH - *Nephrectomy/mt [Methods] MH - Prospective Studies MH - *Robotic Surgical Procedures MH - Time Factors MH - Young Adult AB - OBJECTIVE: To assess the role of robotic-assisted partial nephrectomy (RAPN) in elderly patients focusing on perioperative, functional, and oncologic outcomes in comparison with a younger cohort. AB - MATERIALS AND METHODS: From a prospectively maintained institutional review board-approved database, 339 patients were divided into 2 groups defined by age > 70 (n = 71) or <70 years (n = 268) at the time of RAPN. They were compared for perioperative outcomes and complications, including risk of chronic kidney disease (CKD) stage progression. The standard t test and chi square test were used for continuous and categorical variables, respectively. Logistic regression identified risk factors for progression of renal dysfunction. Kaplan-Meier estimates modeled tumor recurrence at 368 and 462 days in the elderly and young, respectively. AB - RESULTS: Elderly patients were more likely to have hypertension (86% vs 60%; P < .001) or coronary artery disease (27% vs 9%; P < .001), and rates of chronic obstructive pulmonary disorder and diabetes were also higher. Preoperative estimated glomerular filtration rate was significantly lower in the elderly (70 vs 82 mL/min/1.73 m2; P < .001). Twenty-four percent of elderly patients progressed in CKD stage as compared to 14% in the younger cohort (P = .08). Elderly age was not a statistically significant risk factor for CKD progression (relative risk, 2.34; 95% confidence interval, 0.81-6.05; P = .11). Surgical and medical complication rates were similar between the cohorts (P = .75 and .80, respectively) as were Kaplan-Meier estimates of risk of tumor recurrence (P = .47). Limitations include nonrandomized, single-center study, and intermediate-term follow-up for oncologic outcomes. AB - CONCLUSION: Elderly patients undergoing RAPN had no increased risk of perioperative complications. CKD progression and risk of oncologic recurrence were similar to younger patients at intermediate-term follow-up. AB - Copyright © 2014 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(14)00704-3 DO - https://dx.doi.org/10.1016/j.urology.2014.07.004 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 25260445 [pubmed] ID - S0090-4295(14)00704-3 [pii] ID - 10.1016/j.urology.2014.07.004 [doi] PP - ppublish PH - 2014/04/24 [received] PH - 2014/06/22 [revised] PH - 2014/07/01 [accepted] LG - English DP - 2014 Oct DC - 20140927 EZ - 2014/09/28 06:00 DA - 2015/02/05 06:00 DT - 2014/09/28 06:00 YR - 2014 ED - 20150204 RD - 20160606 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25260445 <216. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25102787 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Gordon A AU - Skarecky DW AU - Ahlering T FA - Gordon, Adam FA - Skarecky, Douglas W FA - Ahlering, Thomas IN - Gordon, Adam. Department of Urology, University of California, Irvine, Orange, CA. IN - Skarecky, Douglas W. Department of Urology, University of California, Irvine, Orange, CA. Electronic address: dwskarec@uci.edu. IN - Ahlering, Thomas. Department of Urology, University of California, Irvine, Orange, CA. TI - Long-term outcomes in severe lower urinary tract symptoms in men undergoing robotic-assisted radical prostatectomy. CM - Comment in: Urology. 2014 Oct;84(4):831; PMID: 25102788 SO - Urology. 84(4):826-31, 2014 Oct AS - Urology. 84(4):826-31, 2014 Oct NJ - Urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Humans MH - Lower Urinary Tract Symptoms/co [Complications] MH - *Lower Urinary Tract Symptoms/su [Surgery] MH - Male MH - Middle Aged MH - *Prostatectomy/mt [Methods] MH - *Quality of Life MH - *Robotic Surgical Procedures MH - Severity of Illness Index MH - Time Factors MH - Treatment Outcome MH - Urinary Bladder Neck Obstruction/co [Complications] MH - Urinary Bladder Neck Obstruction/su [Surgery] AB - OBJECTIVE: To address a major concern driving treatment intervention, we studied incontinence and urinary quality of life (QOL) before and after robotic-assisted radical prostatectomy (RARP). In men with severe lower urinary tract symptoms (LUTS), this is the first observational study analyzing short- and long-term urinary outcomes of RARP. AB - MATERIALS AND METHODS: RARP was performed on 665 patients by 1 surgeon from 2002 to 2007. Men returned preoperative and postoperative self-reported American Urological Association symptom score (AUAss), urinary QOL, and continence (pad usage) questionnaires. Men with preoperative severe LUTS (AUAss > 20; n = 53; 8%) were observed longitudinally for a mean of 4.0 years (range, 1.6-9.4 years) and were compared with men with mild-to-moderate LUTS (AUAss < 19; n = 612; 92%). AB - RESULTS: In men with severe LUTS, baseline average AUAss and QOL scores were 24.8 and 4.0, respectively. Long-term AUAss improved by 70% (17 points; P < .001); specifically 59% of patients had AUAss drop to <8, 35% of patients to 8-19, and 6% of patients remained at > 20. The mean QOL scores declined from 4.0 to 2.0 (P < .05). Preoperatively, 38 of 52 patients (73%) had a poor QOL score of 4-6 compared with only 18% (P < .001) at long-term follow-up after RARP. Overall pad-free status was 71% vs 89%. AB - CONCLUSION: In men with severe LUTS, RARP significantly improved urinary symptoms and QOL scores with an overall pad-free status of 71%. Specifically, these men should be counseled that RARP confers a significant short- and long-term benefit with regard to relief of their obstructive and irritative symptoms. AB - Copyright © 2014 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(14)00617-7 DO - https://dx.doi.org/10.1016/j.urology.2014.05.052 PT - Journal Article PT - Observational Study ID - 25102787 [pubmed] ID - S0090-4295(14)00617-7 [pii] ID - 10.1016/j.urology.2014.05.052 [doi] PP - ppublish PH - 2014/03/13 [received] PH - 2014/05/06 [revised] PH - 2014/05/10 [accepted] LG - English EP - 20140805 DP - 2014 Oct DC - 20140927 EZ - 2014/08/09 06:00 DA - 2015/02/05 06:00 DT - 2014/08/12 06:00 YR - 2014 ED - 20150204 RD - 20140927 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25102787 <217. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24264283 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Culligan PJ AU - Gurshumov E AU - Lewis C AU - Priestley JL AU - Komar J AU - Shah N AU - Salamon CG FA - Culligan, Patrick J FA - Gurshumov, Emil FA - Lewis, Christa FA - Priestley, Jennifer L FA - Komar, Jodie FA - Shah, Nihar FA - Salamon, Charbel G IN - Culligan, Patrick J. Atlantic Health System, Urogynecology and Pelvic Reconstructive Surgery, 435 South Street, Suite 370, Morristown, NJ, 07960, USA, patrick.culligan@atlantichealth.org. TI - Subjective and objective results 1 year after robotic sacrocolpopexy using a lightweight Y-mesh. SO - International Urogynecology Journal. 25(6):731-5, 2014 Jun AS - Int Urogynecol J Pelvic Floor Dysfunct. 25(6):731-5, 2014 Jun NJ - International urogynecology journal PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - cl5, 9514583, 101567041 IO - Int Urogynecol J PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544463 SB - Index Medicus CP - England MH - Equipment Design MH - Female MH - Humans MH - *Laparoscopy MH - Middle Aged MH - *Pelvic Organ Prolapse/su [Surgery] MH - Polypropylenes MH - Prospective Studies MH - *Robotic Surgical Procedures MH - Sacrum MH - *Surgical Mesh MH - Surveys and Questionnaires MH - Time Factors MH - Treatment Outcome MH - Urologic Surgical Procedures/is [Instrumentation] MH - Urologic Surgical Procedures/mt [Methods] MH - *Vagina/su [Surgery] AB - INTRODUCTION AND HYPOTHESIS: The objective of this study was to assess outcomes following robotic sacrocolpopexy using a lightweight polypropylene Y-mesh. AB - METHODS: During our study period, all patients who underwent robotic sacrocolpopexy were enrolled in this single-arm prospective trial. Endpoints included Pelvic Organ Prolapse Quantification (POP-Q) values; Pelvic Floor Distress Inventory, short form 20 (PFDI-20); Pelvic Floor Impact Questionnaire, short form 7 (PFIQ-7); Surgical Satisfaction scores; and the Sandvik Incontinence Severity Index. All surgeries were performed with a pre-configured monofilament type 1 polypropylene Y-mesh (Alyte©, C.R. Bard, Covington, GA, USA). Cure rates at 12 months were calculated using two separate definitions: (1) "clinical cure": no POP-Q points>0, point C < -5, no prolapse symptoms on the PFDI-20, and no reoperations for prolapse and (2) "objective anatomic cure": POP-Q stage 0 or 1, point C of < -5, and no reoperations for prolapse. AB - RESULTS: A total of 150 patients underwent robotic sacrocolpopexy and 143 (95 %) were available for 12-month follow-up. Mean age was 58.6 +/- 9.8 and mean body mass index was 26.3 +/- 4.5. Mean operative time and blood loss were 148+/-27.6 min (range 75-250 min) and 51.2+/-32, respectively. There were no mesh erosions or exposures, and mesh edges were not palpable in any patient. At 12 months the clinical cure rate was 95 %, and the objective anatomic cure rate was 84 %. The PFDI-20 mean score improved from 98 at baseline to 17 at 12 months (p<0.0001); PFIQ-7 scores improved from 59 to 6.5 (p<0.0001). AB - CONCLUSIONS: Robotic sacrocolpopexy using this lightweight polypropylene Y-mesh offers excellent subjective and objective results at 1 year. RN - 0 (Polypropylenes) ES - 1433-3023 IL - 0937-3462 DO - https://dx.doi.org/10.1007/s00192-013-2265-x PT - Clinical Trial PT - Journal Article ID - 24264283 [pubmed] ID - 10.1007/s00192-013-2265-x [doi] ID - PMC4544463 [pmc] PP - ppublish PH - 2013/06/10 [received] PH - 2013/10/26 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01320644 SL - https://clinicaltrials.gov/search/term=NCT01320644 LG - English EP - 20131122 DP - 2014 Jun DC - 20140526 EZ - 2013/11/23 06:00 DA - 2015/01/27 06:00 DT - 2013/11/23 06:00 YR - 2014 ED - 20150126 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24264283 <218. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24264283 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Culligan PJ AU - Gurshumov E AU - Lewis C AU - Priestley JL AU - Komar J AU - Shah N AU - Salamon CG FA - Culligan, Patrick J FA - Gurshumov, Emil FA - Lewis, Christa FA - Priestley, Jennifer L FA - Komar, Jodie FA - Shah, Nihar FA - Salamon, Charbel G IN - Culligan, Patrick J. Atlantic Health System, Urogynecology and Pelvic Reconstructive Surgery, 435 South Street, Suite 370, Morristown, NJ, 07960, USA, patrick.culligan@atlantichealth.org. TI - Subjective and objective results 1 year after robotic sacrocolpopexy using a lightweight Y-mesh. SO - International Urogynecology Journal. 25(6):731-5, 2014 Jun AS - Int Urogynecol J Pelvic Floor Dysfunct. 25(6):731-5, 2014 Jun NJ - International urogynecology journal PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - cl5, 9514583, 101567041 IO - Int Urogynecol J PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544463 SB - Index Medicus CP - England MH - Equipment Design MH - Female MH - Humans MH - *Laparoscopy MH - Middle Aged MH - *Pelvic Organ Prolapse/su [Surgery] MH - Polypropylenes MH - Prospective Studies MH - *Robotic Surgical Procedures MH - Sacrum MH - *Surgical Mesh MH - Surveys and Questionnaires MH - Time Factors MH - Treatment Outcome MH - Urologic Surgical Procedures/is [Instrumentation] MH - Urologic Surgical Procedures/mt [Methods] MH - *Vagina/su [Surgery] AB - INTRODUCTION AND HYPOTHESIS: The objective of this study was to assess outcomes following robotic sacrocolpopexy using a lightweight polypropylene Y-mesh. AB - METHODS: During our study period, all patients who underwent robotic sacrocolpopexy were enrolled in this single-arm prospective trial. Endpoints included Pelvic Organ Prolapse Quantification (POP-Q) values; Pelvic Floor Distress Inventory, short form 20 (PFDI-20); Pelvic Floor Impact Questionnaire, short form 7 (PFIQ-7); Surgical Satisfaction scores; and the Sandvik Incontinence Severity Index. All surgeries were performed with a pre-configured monofilament type 1 polypropylene Y-mesh (Alyte©, C.R. Bard, Covington, GA, USA). Cure rates at 12 months were calculated using two separate definitions: (1) "clinical cure": no POP-Q points>0, point C < -5, no prolapse symptoms on the PFDI-20, and no reoperations for prolapse and (2) "objective anatomic cure": POP-Q stage 0 or 1, point C of < -5, and no reoperations for prolapse. AB - RESULTS: A total of 150 patients underwent robotic sacrocolpopexy and 143 (95 %) were available for 12-month follow-up. Mean age was 58.6 +/- 9.8 and mean body mass index was 26.3 +/- 4.5. Mean operative time and blood loss were 148+/-27.6 min (range 75-250 min) and 51.2+/-32, respectively. There were no mesh erosions or exposures, and mesh edges were not palpable in any patient. At 12 months the clinical cure rate was 95 %, and the objective anatomic cure rate was 84 %. The PFDI-20 mean score improved from 98 at baseline to 17 at 12 months (p<0.0001); PFIQ-7 scores improved from 59 to 6.5 (p<0.0001). AB - CONCLUSIONS: Robotic sacrocolpopexy using this lightweight polypropylene Y-mesh offers excellent subjective and objective results at 1 year. RN - 0 (Polypropylenes) ES - 1433-3023 IL - 0937-3462 DO - https://dx.doi.org/10.1007/s00192-013-2265-x PT - Clinical Trial PT - Journal Article ID - 24264283 [pubmed] ID - 10.1007/s00192-013-2265-x [doi] ID - PMC4544463 [pmc] PP - ppublish PH - 2013/06/10 [received] PH - 2013/10/26 [accepted] LG - English EP - 20131122 DP - 2014 Jun DC - 20140526 EZ - 2013/11/23 06:00 DA - 2015/01/27 06:00 DT - 2013/11/23 06:00 YR - 2014 ED - 20150126 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=24264283 <219. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25173122 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Yoo JS AU - Kim JB AU - Jung SH AU - Kim DH AU - Choo SJ AU - Chung CH AU - Lee JW FA - Yoo, Jae Suk FA - Kim, Joon Bum FA - Jung, Sung-Ho FA - Kim, Dae-Hee FA - Choo, Suk Jung FA - Chung, Cheol Hyun FA - Lee, Jae Won IN - Yoo, Jae Suk. Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. IN - Kim, Joon Bum. Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. IN - Jung, Sung-Ho. Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. IN - Kim, Dae-Hee. Department of Cardiology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. IN - Choo, Suk Jung. Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. IN - Chung, Cheol Hyun. Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. IN - Lee, Jae Won. Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. Electronic address: jwlee@amc.seoul.kr. TI - Mitral durability after robotic mitral valve repair: analysis of 200 consecutive mitral regurgitation repairs. SO - Journal of Thoracic & Cardiovascular Surgery. 148(6):2773-9, 2014 Dec AS - J Thorac Cardiovasc Surg. 148(6):2773-9, 2014 Dec NJ - The Journal of thoracic and cardiovascular surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - k9j, 0376343 IO - J. Thorac. Cardiovasc. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Cardiac Surgical Procedures/ae [Adverse Effects] MH - *Cardiac Surgical Procedures/mt [Methods] MH - Cardiac Surgical Procedures/mo [Mortality] MH - Feasibility Studies MH - Female MH - Humans MH - Male MH - Middle Aged MH - Mitral Valve/dg [Diagnostic Imaging] MH - Mitral Valve/pp [Physiopathology] MH - *Mitral Valve/su [Surgery] MH - Mitral Valve Insufficiency/di [Diagnosis] MH - Mitral Valve Insufficiency/mo [Mortality] MH - Mitral Valve Insufficiency/pp [Physiopathology] MH - *Mitral Valve Insufficiency/su [Surgery] MH - Operative Time MH - Recurrence MH - Reoperation MH - Retrospective Studies MH - *Robotics MH - Time Factors MH - Treatment Outcome MH - Ultrasonography AB - OBJECTIVES: The study objective was to review a single-center experience on robotic mitral valve repair to treat mitral regurgitation, with a specific focus on midterm echocardiographic mitral durability. No data assessing the quality or durability of repaired mitral valves are currently available. AB - METHODS: A total of 200 patients who underwent robotic mitral regurgitation repair using the da Vinci system (Intuitive Surgical, Inc, Sunnyvale, Calif) between August 2007 and December 2012 were evaluated. Serial echocardiographic results and operative and procedural times were analyzed. AB - RESULTS: Mitral regurgitation repairs were successfully performed, and no or mild residual mitral regurgitation developed in 98.0% of patients, with no conversion to sternotomy. No in-hospital deaths occurred. Follow-up was completed in 96.5% of patients with a median of 31.4 months (interquartile range, 12.4-42.3 months). During follow-up, 4 late deaths, 2 strokes, 1 low cardiac output, 1 newly required dialysis, and 1 reoperation for mitral regurgitation occurred. Freedom from major adverse cardiac events at 5 years was 87.7% +/- 5.1%. Regular echocardiographic follow-up (>6 months) was achieved in 187 patients (93.5%). At a median of 29.6 months (interquartile range, 14.9-45.8 months), 21 patients (10.5%) demonstrated moderate or greater mitral regurgitation. Freedom from moderate or greater mitral regurgitation at 5 years was 87.0% +/- 2.6%. Mean cardiopulmonary bypass and crossclamping times were 182.9 +/- 48.4 minutes and 110.9 +/- 34.1 minutes, respectively, demonstrating a significant decrease in both times according to the chronologic date of surgery. AB - CONCLUSIONS: Robotic mitral regurgitation repair is technically feasible and efficacious, demonstrating favorable midterm mitral durability and improved procedural times as experience increases. AB - Copyright © 2014 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved. ES - 1097-685X IL - 0022-5223 DI - S0022-5223(14)01026-5 DO - https://dx.doi.org/10.1016/j.jtcvs.2014.07.054 PT - Journal Article PT - Observational Study ID - 25173122 [pubmed] ID - S0022-5223(14)01026-5 [pii] ID - 10.1016/j.jtcvs.2014.07.054 [doi] PP - ppublish PH - 2014/05/01 [received] PH - 2014/06/17 [revised] PH - 2014/07/07 [accepted] LG - English EP - 20140801 DP - 2014 Dec DC - 20141201 EZ - 2014/09/01 06:00 DA - 2015/01/24 06:00 DT - 2014/09/01 06:00 YR - 2014 ED - 20150123 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25173122 <220. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24797846 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Raza SJ AU - Froghi S AU - Chowriappa A AU - Ahmed K AU - Field E AU - Stegemann AP AU - Rehman S AU - Sharif M AU - Shi Y AU - Wilding GE AU - Kesavadas T AU - Kaouk J AU - Guru KA FA - Raza, Syed J FA - Froghi, Saied FA - Chowriappa, Ashirwad FA - Ahmed, Kamran FA - Field, Erinn FA - Stegemann, Andrew P FA - Rehman, Shabnam FA - Sharif, Mohamed FA - Shi, Yi FA - Wilding, Gregory E FA - Kesavadas, Thenkurussi FA - Kaouk, Jihad FA - Guru, Khurshid A IN - Raza, Syed J. Roswell Park Cancer Institute, Buffalo, New York; Department of Urology, MRC Centre for Transplantation, Guy's Hospital, Kings College, London, United Kingdom. IN - Froghi, Saied. Churchill Hospital, Oxford, United Kingdom; Department of Urology, MRC Centre for Transplantation, Guy's Hospital, Kings College, London, United Kingdom. IN - Chowriappa, Ashirwad. Roswell Park Cancer Institute, Buffalo, New York; Department of Urology, MRC Centre for Transplantation, Guy's Hospital, Kings College, London, United Kingdom. IN - Ahmed, Kamran. Department of Urology, MRC Centre for Transplantation, Guy's Hospital, Kings College, London, United Kingdom. IN - Field, Erinn. Roswell Park Cancer Institute, Buffalo, New York; Department of Urology, MRC Centre for Transplantation, Guy's Hospital, Kings College, London, United Kingdom. IN - Stegemann, Andrew P. Roswell Park Cancer Institute, Buffalo, New York; Department of Urology, MRC Centre for Transplantation, Guy's Hospital, Kings College, London, United Kingdom. IN - Rehman, Shabnam. Roswell Park Cancer Institute, Buffalo, New York; Department of Urology, MRC Centre for Transplantation, Guy's Hospital, Kings College, London, United Kingdom. IN - Sharif, Mohamed. Roswell Park Cancer Institute, Buffalo, New York; Department of Urology, MRC Centre for Transplantation, Guy's Hospital, Kings College, London, United Kingdom. IN - Shi, Yi. Roswell Park Cancer Institute, Buffalo, New York; Department of Urology, MRC Centre for Transplantation, Guy's Hospital, Kings College, London, United Kingdom. IN - Wilding, Gregory E. Roswell Park Cancer Institute, Buffalo, New York; Department of Urology, MRC Centre for Transplantation, Guy's Hospital, Kings College, London, United Kingdom. IN - Kesavadas, Thenkurussi. Department of Urology, MRC Centre for Transplantation, Guy's Hospital, Kings College, London, United Kingdom; University at Buffalo, Buffalo, New York. IN - Kaouk, Jihad. Department of Urology, MRC Centre for Transplantation, Guy's Hospital, Kings College, London, United Kingdom; Cleveland Clinic Foundation, Cleveland, Ohio. IN - Guru, Khurshid A. Roswell Park Cancer Institute, Buffalo, New York; Department of Urology, MRC Centre for Transplantation, Guy's Hospital, Kings College, London, United Kingdom. Electronic address: khurshid.guru@roswellpark.org. TI - Construct validation of the key components of Fundamental Skills of Robotic Surgery (FSRS) curriculum--a multi-institution prospective study. SO - Journal of Surgical Education. 71(3):316-24, 2014 May-Jun AS - J Surg Educ. 71(3):316-24, 2014 May-Jun NJ - Journal of surgical education PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101303204 IO - J Surg Educ SB - Index Medicus CP - United States MH - Adult MH - Clinical Competence MH - *Curriculum MH - Female MH - Humans MH - Male MH - Prospective Studies MH - *Robotic Surgical Procedures/ed [Education] MH - Safety KW - FSRS; Medical Knowledge; Practice-Based Learning and Improvement; Systems-Based Practice; curriculum; robot-assisted surgical training; simulation; validity AB - BACKGROUND: Recent incorporation of simulation in surgical training necessitates developing validated platforms for training and assessment. A tool should fulfill the fundamental criteria of validation. AB - OBJECTIVE: To report the ability of a simulation-based robotic training curriculum-Fundamental Skills of Robotic Surgery (FSRS)-to assess and distinguish between different performance levels of operator experience (construct validity). AB - MATERIALS AND METHODS: This is a prospective multicenter observational study. Participants were classified as novice (0 robotic cases performed) and experts (>150 robotic cases performed). All participants were required to complete 4 key tasks in a previously validated FSRS curriculum: ball placement, coordinated tool control, fourth arm control, and needle handling and exchange. Using the metrics available in the simulator software, the performances of each group were compared to evaluate construct validation. AB - RESULTS: A convenience cohort of 61 surgeons participated. Novice group (n = 49) consisted of 41 fellows/residents/medical students and 8 trained open/laparoscopic surgeons, whereas expert group consisted of 12 surgeons. The novice group had no previous robotic console experience, whereas the expert group had >150 prior robotic cases experience. An overall significant difference was observed in favor of the expert group in 4 skill sets (p < 0.05). Time to complete all 4 tasks was significantly shorter in the expert group (p < 0.001). The expert group displayed significantly lesser tool collision (p = 0.002) and reduced tissue damage (p < 0.001). In performing most tasks, the expert group's camera (p < 0.001) and clutch usage (p < 0.001) was significantly greater when compared with the novice group. AB - CONCLUSION: The components of the FSRS curriculum showed construct validity. This validation would help in effectively implementing this curriculum for robot-assisted surgical training. AB - Copyright © 2014 Published by Association of Program Directors in Surgery on behalf of Association of Program Directors in Surgery. ES - 1878-7452 IL - 1878-7452 DI - S1931-7204(13)00272-9 DO - https://dx.doi.org/10.1016/j.jsurg.2013.10.006 PT - Journal Article PT - Multicenter Study PT - Observational Study ID - 24797846 [pubmed] ID - S1931-7204(13)00272-9 [pii] ID - 10.1016/j.jsurg.2013.10.006 [doi] PP - ppublish PH - 2013/06/06 [received] PH - 2013/09/04 [revised] PH - 2013/10/11 [accepted] LG - English EP - 20140102 DP - 2014 May-Jun DC - 20140506 EZ - 2014/05/07 06:00 DA - 2015/01/06 06:00 DT - 2014/05/07 06:00 YR - 2014 ED - 20150105 RD - 20150708 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24797846 <221. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24735243 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hoogendam JP AU - Verheijen RH AU - Wegner I AU - Zweemer RP FA - Hoogendam, J P FA - Verheijen, R H M FA - Wegner, I FA - Zweemer, R P IN - Hoogendam, J P. Department of Gynaecological Oncology, Woman and Baby Division, University Medical Centre Utrecht, Utrecht, the Netherlands. TI - Oncological outcome and long-term complications in robot-assisted radical surgery for early stage cervical cancer: an observational cohort study. SO - BJOG: An International Journal of Obstetrics & Gynaecology. 121(12):1538-45, 2014 Nov AS - BJOG. 121(12):1538-45, 2014 Nov NJ - BJOG : an international journal of obstetrics and gynaecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 100935741 IO - BJOG SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - Adenocarcinoma/mo [Mortality] MH - Adenocarcinoma/pa [Pathology] MH - *Adenocarcinoma/su [Surgery] MH - Adult MH - Aged MH - Aged, 80 and over MH - Carcinoma, Squamous Cell/mo [Mortality] MH - Carcinoma, Squamous Cell/pa [Pathology] MH - *Carcinoma, Squamous Cell/su [Surgery] MH - Female MH - Follow-Up Studies MH - Humans MH - *Hysterectomy/mt [Methods] MH - *Laparoscopy/mt [Methods] MH - Lymph Node Excision/mt [Methods] MH - Middle Aged MH - Neoplasm Recurrence, Local MH - Neoplasm Staging MH - Pelvis MH - Postoperative Complications/ep [Epidemiology] MH - Retrospective Studies MH - *Robotics MH - Survival Analysis MH - Treatment Outcome MH - Uterine Cervical Neoplasms/mo [Mortality] MH - Uterine Cervical Neoplasms/pa [Pathology] MH - *Uterine Cervical Neoplasms/su [Surgery] KW - Cervical cancer; complications; recurrence; robot-assisted laparoscopy; survival AB - OBJECTIVE: To report the oncological outcome and long-term complications of radical surgery by robot-assisted laparoscopy in early stage cervical cancer. AB - DESIGN: Observational cohort study. AB - SETTING: Tertiary referral centre. AB - POPULATION: About 100 cervical cancer patients treated consecutively with robot-assisted radical surgery between 2008 and 2013. AB - METHODS: Two gynaecological oncologists specialised in minimally invasive surgery performed all surgeries on a three/four-armed robotic system. Procedures consisted of pelvic lymph node dissection combined with a radical hysterectomy, radical vaginal trachelectomy or parametrectomy. AB - MAIN OUTCOME MEASURES: Recurrence, survival and long-term complication rates. AB - RESULTS: 104 robot-assisted laparoscopies were performed in 100 patients (stage IA1-IIB), with a median follow-up of 29.5 months (range 2.5-67.1 months). Thirteen cases were diagnosed with a loco-regional (8%), distant (4%) or combined (1%) recurrence at a median of 14.4 months (range 2.9-34.8 months). All mortality (7%) was cervical cancer-related and due to recurrent disease. Four recurrences receive palliative care and two are in complete remission. The overall 5-year progression-free and disease-specific survival rates are 81.4 and 88.7%, respectively. Frequent complications were lymphoedema (26%), lower urinary tract symptoms (19%), urinary tract infection (17%) and sexual disorders (9%). Five patients had a vaginal cuff dehiscence. No complication-related mortality occurred. AB - CONCLUSION: The recurrence, survival and long-term complication rates of robot-assisted radical surgery for early stage cervical cancer in this cohort are reassuring concerning its continued clinical use. AB - Copyright © 2014 Royal College of Obstetricians and Gynaecologists. ES - 1471-0528 IL - 1470-0328 DO - https://dx.doi.org/10.1111/1471-0528.12822 PT - Evaluation Studies PT - Journal Article ID - 24735243 [pubmed] ID - 10.1111/1471-0528.12822 [doi] PP - ppublish PH - 2014/03/10 [accepted] LG - English EP - 20140416 DP - 2014 Nov DC - 20141028 EZ - 2014/04/17 06:00 DA - 2014/12/30 06:00 DT - 2014/04/17 06:00 YR - 2014 ED - 20141224 RD - 20141028 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24735243 <222. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24360715 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lee HS AU - Kim D AU - Lee SY AU - Byeon HK AU - Kim WS AU - Hong HJ AU - Koh YW AU - Choi EC FA - Lee, Hyoung Shin FA - Kim, Dae FA - Lee, So Yoon FA - Byeon, Hyung Kwon FA - Kim, Won Shik FA - Hong, Hyun Jun FA - Koh, Yoon Woo FA - Choi, Eun Chang IN - Lee, Hyoung Shin. Department of Otolaryngology Head and Neck Surgery, Kosin University College of Medicine, Busan, South Korea. IN - Kim, Dae. Department of Otolaryngology and Head and Neck Surgery, Queen Alexandra Hospital, Portsmouth & Cancer Sciences, University of Southampton, United Kingdom. IN - Lee, So Yoon. Department of Otolaryngology Head and Neck Surgery, Catholic University College of Medicine, Seoul, South Korea. IN - Byeon, Hyung Kwon. Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, South Korea. IN - Kim, Won Shik. Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, South Korea. IN - Hong, Hyun Jun. Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, South Korea. IN - Koh, Yoon Woo. Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, South Korea. Electronic address: ywkohent@yuhs.ac. IN - Choi, Eun Chang. Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, South Korea. TI - Robot-assisted versus endoscopic submandibular gland resection via retroauricular approach: a prospective nonrandomized study. SO - British Journal of Oral & Maxillofacial Surgery. 52(2):179-84, 2014 Feb AS - Br J Oral Maxillofac Surg. 52(2):179-84, 2014 Feb NJ - The British journal of oral & maxillofacial surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - azr, 8405235 IO - Br J Oral Maxillofac Surg SB - Dental Journals SB - Index Medicus CP - Scotland MH - Adenoma, Pleomorphic/su [Surgery] MH - Adolescent MH - Adult MH - Blood Loss, Surgical MH - Drainage MH - *Endoscopy/mt [Methods] MH - Esthetics MH - Feasibility Studies MH - Female MH - Follow-Up Studies MH - Hospitalization MH - Humans MH - Length of Stay MH - Male MH - Middle Aged MH - Operative Time MH - Patient Satisfaction MH - Postoperative Complications MH - Prospective Studies MH - *Robotics/mt [Methods] MH - Sialadenitis/su [Surgery] MH - *Submandibular Gland Diseases/su [Surgery] MH - Submandibular Gland Neoplasms/su [Surgery] MH - Treatment Outcome MH - Young Adult KW - Endoscopic; Face lift; Hairline; Robotic; Submandibular gland AB - The aim of this study was to compare the short-term clinicopathological results of robot-assisted and endoscopic resection of the submandibular gland by the retroauricular approach. We present a prospective, non-random, study of 35 patients who had endoscope-assisted (n=22), or robot-assisted (n=13), resection of the submandibular gland using a retroauricular approach. Patients selected one of the two methods, and short-term clinical outcomes were then compared, including maximum diameter of the tumour and gland, length of incision, total operating time, amount of operative bleeding, amount and duration of drainage, duration of hospital stay, cosmesis, and complications. The operation was feasible in all patients with no appreciable operative complications or need to convert to a conventional open operation. The operating time of the robot-assisted group (63.4 (6.3)min) was comparable with that of the endoscopic group (66.5 (9.1)min) (p=0.15). There were no differences in the other clinical outcomes between the 2 groups. Both groups of patients were extremely satisfied with their postoperative cosmesis, and did not differ significantly (p=0.89). Robotic and endoscopic resection of the submandibular gland gave comparable early surgical outcomes and excellent cosmetic results. Despite the technical convenience for the surgeon, the robot gave no apparent clinical benefit over the endoscope in this series. AB - Copyright © 2013 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved. ES - 1532-1940 IL - 0266-4356 DI - S0266-4356(13)00478-6 DO - https://dx.doi.org/10.1016/j.bjoms.2013.11.002 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 24360715 [pubmed] ID - S0266-4356(13)00478-6 [pii] ID - 10.1016/j.bjoms.2013.11.002 [doi] PP - ppublish PH - 2013/07/12 [received] PH - 2013/11/02 [accepted] LG - English EP - 20131217 DP - 2014 Feb DC - 20140127 EZ - 2013/12/24 06:00 DA - 2014/12/15 06:00 DT - 2013/12/24 06:00 YR - 2014 ED - 20141203 RD - 20140127 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24360715 <223. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24559757 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kam CC AU - Greenberg JA FA - Kam, Check C FA - Greenberg, Jeffrey A IN - Kam, Check C. South Florida Orthopaedics and Sports Medicine, Stuart, FL; Indiana Hand to Shoulder Center, Indianapolis, IN. Electronic address: Check.kam.md@gmail.com. IN - Greenberg, Jeffrey A. South Florida Orthopaedics and Sports Medicine, Stuart, FL; Indiana Hand to Shoulder Center, Indianapolis, IN. TI - Computer-assisted navigation for dorsal percutaneous scaphoid screw placement: a cadaveric study. SO - Journal of Hand Surgery - American Volume. 39(4):613-20, 2014 Apr AS - J Hand Surg [Am]. 39(4):613-20, 2014 Apr NJ - The Journal of hand surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - ia9, 7609631 IO - J Hand Surg Am SB - Index Medicus CP - United States MH - Bone Screws MH - Cadaver MH - Clinical Protocols MH - Fluoroscopy MH - Fractures, Bone/dg [Diagnostic Imaging] MH - *Fractures, Bone/su [Surgery] MH - Humans MH - Operative Time MH - Scaphoid Bone/dg [Diagnostic Imaging] MH - *Scaphoid Bone/in [Injuries] MH - *Surgery, Computer-Assisted/mt [Methods] MH - Tomography, X-Ray Computed MH - *Wrist Injuries/su [Surgery] KW - Navigation; percutaneous; scaphoid AB - PURPOSE: To investigate computer-assisted surgery (CAS) for dorsal insertion of percutaneous scaphoid screws and to compare operative time, accuracy, and fluoroscopy time with the traditional mini C-arm method. We hypothesized that CAS techniques would improve accuracy, reduce actual K-wire insertion time, and decrease fluoroscopy time. AB - METHODS: Ten fresh cadaveric upper limbs were randomized to either CAS or traditional dorsal percutaneous scaphoid screw placement by a single surgeon. Custom orthoses were applied to the CAS arms followed by intraoperative computed tomography (CT) scan and navigation calibration. Time was recorded for the portion of setup that required surgeon input, ideal guide wire placement, and fluoroscopy. Postoperative CT scans of the CAS arms were obtained to confirm accuracy. Two-tailed unpaired Student t test was used to analyze the outcome variables. AB - RESULTS: The CAS group required on average 4.8 +/- 0.8 minutes longer for setup. The time for placement of the guidewire in the ideal position was 4.6 +/- 1.5 minutes in the CAS group compared with 11.8 +/- 4.4 minutes in the control group. Fluoroscopy time was 18 +/- 4 seconds for the CAS group and 114 +/- 38 seconds for the control group. Postoperative CT scans demonstrated 1.5 +/- 0.6 mm maximum deviation from the planned ideal screw. No significant differences were found in the accuracy between methods, the number of guidewire attempts, or the total surgical time. AB - CONCLUSIONS: Computer-assisted surgery navigation of dorsal percutaneous scaphoid screw placement takes on average 5 minutes longer to set up, but leads to significantly reduced guidewire placement time and no differences in overall procedural time. This CAS method was as accurate as the traditional method and resulted in an approximate 6-fold reduction in fluoroscopy time. AB - CLINICAL RELEVANCE: This is an effective imaging alternative to the mini C-arm for scaphoid fixation using existing intraoperative CT scanners and navigation software. AB - Copyright © 2014 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved. ES - 1531-6564 IL - 0363-5023 DI - S0363-5023(14)00003-3 DO - https://dx.doi.org/10.1016/j.jhsa.2013.12.032 PT - Journal Article PT - Randomized Controlled Trial ID - 24559757 [pubmed] ID - S0363-5023(14)00003-3 [pii] ID - 10.1016/j.jhsa.2013.12.032 [doi] PP - ppublish PH - 2013/05/07 [received] PH - 2013/12/22 [revised] PH - 2013/12/27 [accepted] LG - English EP - 20140220 DP - 2014 Apr DC - 20140331 EZ - 2014/02/25 06:00 DA - 2014/12/15 06:00 DT - 2014/02/25 06:00 YR - 2014 ED - 20141201 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24559757 <224. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25419071 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - PubMed-not-MEDLINE AU - Somashekhar SP AU - Jaka RC AU - Zaveri SS FA - Somashekhar, S P FA - Jaka, Rajshekhar C FA - Zaveri, Shabber S IN - Somashekhar, S P. Department of Surgical Oncology, Manipal Comprehensive Cancer Center, Manipal Hospital, HAL airport road, Bangalore, 560017 Karnataka state India. IN - Jaka, Rajshekhar C. Department of Surgical Oncology, Manipal Comprehensive Cancer Center, Manipal Hospital, HAL airport road, Bangalore, 560017 Karnataka state India. IN - Zaveri, Shabber S. Department of Surgical Oncology, Manipal Comprehensive Cancer Center, Manipal Hospital, HAL airport road, Bangalore, 560017 Karnataka state India. TI - Prospective randomized study comparing robotic-assisted hysterectomy and regional lymphadenectomy with traditional laparotomy for staging of endometrial carcinoma -initial Indian experience. SO - Indian Journal of Surgical Oncology. 5(3):217-23, 2014 Sep AS - Indian j. surg. oncol.. 5(3):217-23, 2014 Sep NJ - Indian journal of surgical oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Print JC - 101532448 IO - Indian J Surg Oncol PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235873 CP - India KW - Endometrial cancer; Hysterectomy; Robotic assisted surgery; Staging laparotomy AB - Robotic assisted hysterectomy with regional lymphadenectomy is increasingly used for the treatment of endometrial carcinoma. In the present study we evaluated the feasibility and technique of robotic assisted hysterectomy and lymphadenectomy in patients with endometrial carcinoma. A prospective randomized study was undertaken from July 2011 to June 2012, in 50 consecutive patients with carcinoma endometrium. Demographic (age, BMI) and perioperative data (operating time, estimated blood loss, total number of lymph nodes retrieved, hospital stay, conversion to open procedure, intraoperative and postoperative complications) of robotic assisted surgery were compared with open staging procedure. Mean age of the patient and BMI in both groups were comparable with no significant difference. Estimated blood loss (81.28 ml), hospital stay (1.94 days) and perioperative complications were significantly less in robotic assisted group in comparison to open method. Mean number of lymph nodes removed were 30.56 versus 27.6 which is suggestive of significant difference statistically. Operative time decreased as the experience of the surgeon increased but still significantly remained higher than the open procedure after 25 robotic assisted surgeries. All robotic surgeries were completed successfully without converting to open method. Robotic assisted staging procedure for endometrial carcinoma is feasible without converting to open method, with the advantages of decreased blood loss, short duration of hospital stay and less postoperative minor complications. Operative time will decrease further as the experience of surgeon increases. Para-aortic lymph node dissection is easily done and with a better ergonomics for surgeon. IS - 0975-7651 IL - 0975-7651 DI - 321 DO - https://dx.doi.org/10.1007/s13193-014-0321-8 PT - Journal Article ID - 25419071 [pubmed] ID - 10.1007/s13193-014-0321-8 [doi] ID - 321 [pii] ID - PMC4235873 [pmc] PP - ppublish PH - 2012/10/20 [received] PH - 2014/06/06 [accepted] LG - English EP - 20140621 DP - 2014 Sep DC - 20141124 EZ - 2014/11/25 06:00 DA - 2014/11/25 06:01 DT - 2014/11/25 06:00 YR - 2014 ED - 20141124 RD - 20150902 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=25419071 <225. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24570078 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Huh H AU - Kim NY AU - Park SJ AU - Cho JE FA - Huh, Hyub FA - Kim, Na Young FA - Park, Seol Ju FA - Cho, Jang Eun IN - Huh, Hyub. Department of Anaesthesia and Pain Medicine, Anam Hospital, Korea University, Seoul, South Korea. TI - Effect of nicardipine on renal function following robot-assisted laparoscopic radical prostatectomy in patients with pre-existing renal insufficiency. SO - Journal of International Medical Research. 42(2):427-35, 2014 Apr AS - J Int Med Res. 42(2):427-35, 2014 Apr NJ - The Journal of international medical research PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - e62, 0346411 IO - J. Int. Med. Res. SB - Index Medicus CP - England MH - Aged MH - Aged, 80 and over MH - Antihypertensive Agents/tu [Therapeutic Use] MH - Calcium Channel Blockers/tu [Therapeutic Use] MH - Creatinine/bl [Blood] MH - Glomerular Filtration Rate MH - Humans MH - *Kidney/pa [Pathology] MH - Kidney Function Tests MH - Laparoscopy MH - Male MH - Middle Aged MH - *Nicardipine/tu [Therapeutic Use] MH - Pneumoperitoneum MH - Prospective Studies MH - Prostate/su [Surgery] MH - *Prostatectomy MH - *Renal Insufficiency/pc [Prevention & Control] MH - Robotics KW - Nicardipine; renal insufficiency; robot-assisted surgery AB - OBJECTIVE: To investigate the renoprotective effect of nicardipine in patients with pre-existing renal insufficiency undergoing robot-assisted laparoscopic radical prostatectomy (RALRP). AB - METHODS: Men with preoperative renal insufficiency (estimated glomerular filtration rate [eGFR] <60 ml/min per 1.73 m(2)) were enrolled and randomized to receive either 0.5 micro g/kg per min nicardipine continuous infusion (nicardipine group) or normal saline (control group) during RALRP. Renal function was determined by eGFR and serum creatinine concentration. AB - RESULTS: Serum creatinine levels on postoperative days (POD) 1 and 3 were significantly lower than baseline values in the nicardipine group (n = 50). In the control group (n = 50), eGFR was significantly higher on POD 3 than baseline, and was significantly higher than baseline on POD 1 and 3 in the nicardipine group. The change in eGFR from baseline to POD 1 was significantly higher in the nicardipine group than the control group. AB - CONCLUSION: Continuous infusion of nicardipine during RALRP improved postoperative renal function on POD 1 in patients with pre-existing renal insufficiency. RN - 0 (Antihypertensive Agents) RN - 0 (Calcium Channel Blockers) RN - AYI8EX34EU (Creatinine) RN - CZ5312222S (Nicardipine) ES - 1473-2300 IL - 0300-0605 DI - 0300060513510435 DO - https://dx.doi.org/10.1177/0300060513510435 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 24570078 [pubmed] ID - 0300060513510435 [pii] ID - 10.1177/0300060513510435 [doi] PP - ppublish LG - English EP - 20140225 DP - 2014 Apr DC - 20140320 EZ - 2014/02/27 06:00 DA - 2014/11/19 06:00 DT - 2014/02/27 06:00 YR - 2014 ED - 20141118 RD - 20140320 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24570078 <226. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24388099 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Menon M AU - Sood A AU - Bhandari M AU - Kher V AU - Ghosh P AU - Abaza R AU - Jeong W AU - Ghani KR AU - Kumar RK AU - Modi P AU - Ahlawat R FA - Menon, Mani FA - Sood, Akshay FA - Bhandari, Mahendra FA - Kher, Vijay FA - Ghosh, Prasun FA - Abaza, Ronney FA - Jeong, Wooju FA - Ghani, Khurshid R FA - Kumar, Ramesh K FA - Modi, Pranjal FA - Ahlawat, Rajesh IN - Menon, Mani. Vattikuti Urology Institute, Henry Ford Hospital, Detroit, MI, USA. IN - Sood, Akshay. Vattikuti Urology Institute, Henry Ford Hospital, Detroit, MI, USA. Electronic address: asood1@hfhs.org. IN - Bhandari, Mahendra. Vattikuti Urology Institute, Henry Ford Hospital, Detroit, MI, USA. IN - Kher, Vijay. Kidney and Urology Institute, Medanta-The Medicity, Gurgaon, India. IN - Ghosh, Prasun. Kidney and Urology Institute, Medanta-The Medicity, Gurgaon, India. IN - Abaza, Ronney. Department of Urology, Ohio State University, Columbus, OH, USA. IN - Jeong, Wooju. Vattikuti Urology Institute, Henry Ford Hospital, Detroit, MI, USA. IN - Ghani, Khurshid R. Vattikuti Urology Institute, Henry Ford Hospital, Detroit, MI, USA. IN - Kumar, Ramesh K. Vattikuti Urology Institute, Henry Ford Hospital, Detroit, MI, USA. IN - Modi, Pranjal. Department of Urology, H.L. Trivedi Institute of Transplantation Sciences, Ahmedabad, India. IN - Ahlawat, Rajesh. Kidney and Urology Institute, Medanta-The Medicity, Gurgaon, India. TI - Robotic kidney transplantation with regional hypothermia: a step-by-step description of the Vattikuti Urology Institute-Medanta technique (IDEAL phase 2a). CM - Comment in: Eur Urol. 2014 Jun;65(6):e88; PMID: 24589331 CM - Comment in: Eur Urol. 2014 Jun;65(6):e87; PMID: 24589332 SO - European Urology. 65(5):991-1000, 2014 May AS - Eur Urol. 65(5):991-1000, 2014 May NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Adolescent MH - Adult MH - Aged MH - Female MH - Humans MH - *Hypothermia, Induced/mt [Methods] MH - Kidney Transplantation/ae [Adverse Effects] MH - *Kidney Transplantation/mt [Methods] MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - Operative Time MH - Practice Guidelines as Topic MH - Prospective Studies MH - *Robotics/mt [Methods] MH - Warm Ischemia MH - Young Adult KW - Hypothermia; IDEAL guidelines; Kidney; Kidney transplantation; Minimally invasive surgery; Robotics AB - BACKGROUND: We recently reported on preclinical and feasibility studies (Innovation, Development, Exploration, Assessment, Long-term study [IDEAL] phase 0-1) of the development of robotic kidney transplantation (RKT) with regional hypothermia. This paper presents the IDEAL phase 2a studies of technique development. AB - OBJECTIVES: To describe the technique of RKT with regional hypothermia developed at two tertiary care institutions (Vattikuti Urology Institute and Medanta Hospital). We report on the safety profile and early graft function in these patients. AB - DESIGN, SETTING, AND PARTICIPANTS: This is a prospective study of 50 consecutive patients who underwent live-donor RKT at Medanta Hospital following a 3-yr planning/simulation phase at the Vattikuti Urology Institute. Demographic details, and perioperative and postoperative outcomes are reported for the initial 25 recipients who have completed a minimum 6-mo follow-up. AB - SURGICAL PROCEDURE: Positioning and port placement were similar to that used for robotic radical prostatectomy. Allograft cooling was achieved by ice slush delivered through a GelPOINT device. The accompanying video details the operative technique. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: The primary outcome was posttransplant graft function. Secondary outcomes included technical success or failure and complication rates. AB - RESULTS AND LIMITATIONS: Fifty patients underwent RKT successfully, 7 in the phase 1 and 43 in the phase 2 stages of the study. For the initial 25 patients, mean console, warm ischemia, arterial, and venous anastomotic times were 135, 2.4, 12, and 13.4 min, respectively. All grafts were cooled to 18-20 degreeC with no change in core body temperature. All grafts functioned immediately posttransplant and the mean serum creatinine level at discharge was 1.3mg/dl (range: 0.8-3.1mg/dl). No patient developed anastomotic leaks, wound complications, or wound infections. At 6-mo of follow-up, no patient had developed a lymphocele detected on CT scanning. Two patients underwent re-exploration, and one patient died of congestive heart failure (1.5 mo posttransplant). AB - CONCLUSIONS: RKT with regional hypothermia is safe and reproducible when performed by a team skilled in robotic surgery. AB - PATIENT SUMMARY: RKT is safe and effective when performed by surgeons experienced in robotic techniques. AB - Copyright © 2013 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(13)01327-4 DO - https://dx.doi.org/10.1016/j.eururo.2013.12.006 PT - Clinical Trial, Phase II PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 24388099 [pubmed] ID - S0302-2838(13)01327-4 [pii] ID - 10.1016/j.eururo.2013.12.006 [doi] PP - ppublish PH - 2013/11/05 [received] PH - 2013/12/05 [accepted] LG - English EP - 20131219 DP - 2014 May DC - 20140319 EZ - 2014/01/07 06:00 DA - 2014/11/18 06:00 DT - 2014/01/07 06:00 YR - 2014 ED - 20141117 RD - 20151026 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24388099 <227. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23495792 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Riikonen J AU - Kaipia A AU - Matikainen M AU - Koskimaki J AU - Kylmala T AU - Tammela TL FA - Riikonen, Jarno FA - Kaipia, Antti FA - Matikainen, Mika FA - Koskimaki, Juha FA - Kylmala, Timo FA - Tammela, Teuvo L IN - Riikonen, Jarno. Tampere University Hospital , Tampere , Finland. TI - Side-fenestrated catheter decreases leakage at the urethrovesical anastomosis after robot-assisted laparoscopic radical prostatectomy. SO - Scandinavian Journal of Urology. 48(1):21-6, 2014 Feb AS - Scand J Urol. 48(1):21-6, 2014 Feb NJ - Scandinavian journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101587186 IO - Scand J Urol SB - Index Medicus CP - England MH - Adult MH - Aged MH - Anastomosis, Surgical MH - *Anastomotic Leak/pc [Prevention & Control] MH - *Catheters MH - Equipment Design MH - Humans MH - *Laparoscopy MH - Male MH - Middle Aged MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Robotics MH - Single-Blind Method MH - *Urethra/su [Surgery] MH - *Urinary Bladder/su [Surgery] AB - OBJECTIVE: The aim of this study was to analyse whether a side-fenestrated urinary catheter can decrease the frequency of anastomotic leakage after robot-assisted laparoscopic radical prostatectomy (RALP). AB - MATERIAL AND METHODS: Two-hundred and fifty patients with localized prostate cancer undergoing RALP were randomized into standard and side-fenestrated catheter groups in a prospective randomized study. The catheter was fenestrated at the site of the anastomosis to improve drainage. A cystogram was taken at 7 +/- 2 days postoperatively to verify the watertightness of the anastomosis. The patients were monitored for 3 months. AB - RESULTS: The study included 106 patients with the standard and 108 patients with the fenestrated catheter. Leakage at the urethrovesical anastomosis was found in 13/106 (12.3%) of the standard and 5/108 (4.6%) of the side-fenestrated catheter patients (p = 0.044). Discomfort induced by the catheter and urinary leakage beside the catheter did not differ between the groups. The clinical and pathological characteristics and complications were equal between the groups. AB - CONCLUSIONS: The side-fenestrated catheter decreased leakage rates at the urethrovesical anastomosis after RALP. ES - 2168-1813 IL - 2168-1805 DO - https://dx.doi.org/10.3109/21681805.2013.777365 PT - Journal Article PT - Randomized Controlled Trial ID - 23495792 [pubmed] ID - 10.3109/21681805.2013.777365 [doi] PP - ppublish LG - English EP - 20130315 DP - 2014 Feb DC - 20140303 EZ - 2013/03/19 06:00 DA - 2014/11/18 06:00 DT - 2013/03/19 06:00 YR - 2014 ED - 20141117 RD - 20151022 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23495792 <228. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23575913 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Vallabhajosula S AU - Judkins TN AU - Mukherjee M AU - Suh IH AU - Oleynikov D AU - Siu KC FA - Vallabhajosula, Srikant FA - Judkins, Timothy N FA - Mukherjee, Mukul FA - Suh, Irene H FA - Oleynikov, Dmitry FA - Siu, Ka-Chun IN - Vallabhajosula, Srikant. 1Elon University, Elon, NC, USA. TI - Skills learning in robot-assisted surgery is benefited by task-specific augmented feedback. SO - Surgical Innovation. 20(6):639-47, 2013 Dec AS - Surg Innov. 20(6):639-47, 2013 Dec NJ - Surgical innovation PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101233809 IO - Surg Innov SB - Index Medicus CP - United States MH - Adult MH - Clinical Competence MH - Education, Medical, Continuing MH - Feedback MH - Humans MH - *Robotics/ed [Education] MH - *Surgery, Computer-Assisted/ed [Education] MH - *Task Performance and Analysis MH - Young Adult KW - concurrent feedback; da Vinci Surgical System; motor learning; task complexity AB - BACKGROUND: Providing augmented visual feedback is one way to enhance robot-assisted surgery (RAS) training. However, it is unclear whether task specificity should be considered when applying augmented visual feedback. AB - METHODS: Twenty-two novice users of the da Vinci Surgical System underwent testing and training in 3 tasks: simple task, bimanual carrying (BC); intermediate task, needle passing (NP); and complex task, suture tying (ST). Pretraining (PRE), training, and posttraining (POST) trials were performed during the first session. Retention trials were performed 2 weeks later (RET). Participants were randomly assigned to 1 of 4 feedback training groups: relative phase (RP), speed, grip force, and video feedback groups. Performance measures were time to task completion (TTC), total distance traveled (D), speed (S), curvature, relative phase, and grip force (F). AB - RESULTS: Significant interaction for TTC and curvature showed that the RP feedback training improved temporal measures of complex ST task compared to simple BC task. Speed feedback training significantly improved the performance in simple BC task in terms of TTC, D, S, curvature, and F even after retention. There was also a lesser long-term effect of speed feedback training on complex ST task. Grip force feedback training resulted in significantly greater improvements in TTC and curvature for complex ST task. For the video feedback training group, the improvements in most of the outcome measures were evident only after RET. AB - CONCLUSIONS: Task-specific augmented feedback is beneficial to RAS skills learning. Particularly, the RP and grip force feedback could be useful for training complex tasks. ES - 1553-3514 IL - 1553-3506 DI - 1553350613484590 DO - https://dx.doi.org/10.1177/1553350613484590 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 23575913 [pubmed] ID - 1553350613484590 [pii] ID - 10.1177/1553350613484590 [doi] PP - ppublish LG - English EP - 20130410 DP - 2013 Dec DC - 20140221 EZ - 2013/04/12 06:00 DA - 2014/11/18 06:00 DT - 2013/04/12 06:00 YR - 2013 ED - 20141117 RD - 20150113 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23575913 <229. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24217787 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Barrie J AU - Jayne DG AU - Wright J AU - Murray CJ AU - Collinson FJ AU - Pavitt SH FA - Barrie, Jenifer FA - Jayne, David G FA - Wright, Judy FA - Murray, Carolyn J Czoski FA - Collinson, Fiona J FA - Pavitt, Sue H IN - Barrie, Jenifer. Division of Clinical Sciences, Leeds Institute of Molecular Medicine, The University of Leeds, Leeds, UK. TI - Attaining surgical competency and its implications in surgical clinical trial design: a systematic review of the learning curve in laparoscopic and robot-assisted laparoscopic colorectal cancer surgery. [Review] SO - Annals of Surgical Oncology. 21(3):829-40, 2014 Mar AS - Ann Surg Oncol. 21(3):829-40, 2014 Mar NJ - Annals of surgical oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - b9r, 9420840 IO - Ann. Surg. Oncol. SB - Index Medicus CP - United States MH - *Clinical Competence MH - *Clinical Trials as Topic MH - *Colorectal Neoplasms/su [Surgery] MH - *Colorectal Surgery/ed [Education] MH - Humans MH - *Laparoscopy/ed [Education] MH - Prognosis MH - *Research Design MH - *Robotics/ed [Education] AB - BACKGROUND: Laparoscopic surgery is increasingly used in the treatment of colorectal cancer and more recently robotic assistance has been advocated. However, the learning curve to achieve surgical proficiency in laparoscopic surgery is ill-defined and subject to many influences. The aim of this review was to comprehensively appraise the literature on the learning curve for laparoscopic and robotic colorectal cancer surgery, and to quantify attainment of surgical proficiency and its implications in surgical clinical trial design. AB - METHODS: A systematic review using a defined search strategy was performed. Included studies had to state an explicit numerical value of the learning curve evaluated by a single parameter or multiple parameters. AB - RESULTS: Thirty-four studies were included, 28 laparoscopic and 6 robot assisted. Of the laparoscopic studies, nine defined the learning curve on the basis of a single parameter. Nine studies used more than one parameter to define learning, and 11 used a cumulative sum (CUSUM) analysis. One study used both a multiparameter and CUSUM analysis. The definition of proficiency was subjective, and the number of operations to achieve it ranged from 5 to 310 cases for laparoscopic and 15-30 cases for robotic surgery. AB - CONCLUSIONS: The learning curve in laparoscopic colorectal surgery is multifaceted and often ill-defined, with poor descriptions of mentorship/supervision. Further, the quantification to attain proficiency is variable. The use of a single parameter to quantify this is simplistic. Multidimensional assessment is recommended; as part of this, the CUSUM model, which assesses trends in multiple surgical outcomes, is useful and appropriate when assessing the learning curve in a clinical setting. ES - 1534-4681 IL - 1068-9265 DO - https://dx.doi.org/10.1245/s10434-013-3348-0 PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review ID - 24217787 [pubmed] ID - 10.1245/s10434-013-3348-0 [doi] PP - ppublish PH - 2012/11/14 [received] LG - English EP - 20131112 DP - 2014 Mar DC - 20140225 EZ - 2013/11/13 06:00 DA - 2014/11/14 06:00 DT - 2013/11/13 06:00 YR - 2014 ED - 20141113 RD - 20140225 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24217787 <230. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24202713 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Noshiro H AU - Ikeda O AU - Urata M FA - Noshiro, Hirokazu FA - Ikeda, Osamu FA - Urata, Masako IN - Noshiro, Hirokazu. Department of Surgery, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga, 849-8501, Japan, noshiro@cc.saga-u.ac.jp. TI - Robotically-enhanced surgical anatomy enables surgeons to perform distal gastrectomy for gastric cancer using electric cautery devices alone. SO - Surgical Endoscopy. 28(4):1180-7, 2014 Apr AS - Surg Endosc. 28(4):1180-7, 2014 Apr NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Aged MH - *Catheter Ablation/is [Instrumentation] MH - Equipment Design MH - Feasibility Studies MH - Female MH - Follow-Up Studies MH - *Gastrectomy/is [Instrumentation] MH - Humans MH - Male MH - Prospective Studies MH - *Robotics MH - *Stomach Neoplasms/su [Surgery] MH - Treatment Outcome AB - BACKGROUND: Despite recent advances in robotic urological surgery, the feasibility and clinical merit of robotic gastric surgery have not yet been fully documented. Therefore, we designed a prospective, non-randomized study to determine the feasibility and safety of robot-assisted distal gastrectomy (RADG) for gastric cancer using electric cautery devices, which are more familiar to open surgery. AB - METHODS: Between April 2010 and December 2012, 181 patients treated by distal gastrectomy for gastric carcinoma were eligible for this study. According to their intent to undergo uninsured robotic surgery, 21 patients were treated with RADG (RADG group) while 160 patients were treated by conventional laparoscopic distal gastrectomy (LDG group). Under a basic working hypothesis that the superior visualization and unique movement of the robotic arms during dissection would be closely associated with reduced amount of blood loss, even though an equivalent extension of lymph node dissection was carried out, we prospectively collected data from patients in the RADG and LDG groups. AB - RESULTS: All patients were successfully treated without conversion except for one patient in the RADG group who underwent conversion to laparoscopic total gastrectomy. In comparison with the patient groups, the estimated blood loss in patients in the RADG group treated with electric cautery devices only was smaller, but not significantly, than patients in the LDG group treated with ultrasonic-activated devices, although the same extent of lymph node dissection was achieved. In contrast, there were four patients (2.5 %) in the LDG group who developed a pancreas fistula or intra-abdominal abscess, while no patients treated with RADG developed such complications. AB - CONCLUSIONS: RADG using electric cautery instruments without ultrasonic-activated devices is feasible and safe. The robot enables particular surgical views, called robotically-enhanced surgical anatomy, and may contribute to reducing blood loss despite the fact that only electric cautery was used. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-013-3304-x PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 24202713 [pubmed] ID - 10.1007/s00464-013-3304-x [doi] PP - ppublish PH - 2013/05/11 [received] PH - 2013/08/07 [accepted] LG - English EP - 20131108 DP - 2014 Apr DC - 20140404 EZ - 2013/11/09 06:00 DA - 2014/10/22 06:00 DT - 2013/11/10 06:00 YR - 2014 ED - 20141021 RD - 20140404 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24202713 <231. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24706455 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Durmus K AU - Patwa HS AU - Gokozan HN AU - Kucur C AU - Teknos TN AU - Agrawal A AU - Old MO AU - Ozer E FA - Durmus, Kasim FA - Patwa, Hafiz S FA - Gokozan, Hamza N FA - Kucur, Cuneyt FA - Teknos, Theodoros N FA - Agrawal, Amit FA - Old, Matthew O FA - Ozer, Enver IN - Durmus, Kasim. Department of Otolaryngology-Head and Neck Surgery, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, Ohio, U.S.A. TI - Functional and quality-of-life outcomes of transoral robotic surgery for carcinoma of unknown primary. SO - Laryngoscope. 124(9):2089-95, 2014 Sep AS - Laryngoscope. 124(9):2089-95, 2014 Sep NJ - The Laryngoscope PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 8607378, l1w IO - Laryngoscope PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266325 OI - Source: NLM. NIHMS646267 SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Carcinoma, Squamous Cell/sc [Secondary] MH - *Carcinoma, Squamous Cell/su [Surgery] MH - Female MH - Follow-Up Studies MH - *Head and Neck Neoplasms/su [Surgery] MH - Humans MH - Lymphatic Metastasis MH - Male MH - Middle Aged MH - Mouth MH - *Neoplasms, Unknown Primary/su [Surgery] MH - Prospective Studies MH - *Quality of Life MH - *Recovery of Function MH - *Robotics/mt [Methods] MH - Time Factors MH - Treatment Outcome KW - Transoral robotic surgery; carcinoma of unknown primary; neck metastasis; quality of life; transoral robotic surgery AB - OBJECTIVES/HYPOTHESIS: To determine speech, eating, aesthetics, social disruption, and overall quality-of-life outcomes over a year period in patients who underwent transoral robotic surgery as part of carcinoma of unknown primary diagnosis and treatment. AB - STUDY DESIGN: Observational prospective study. AB - METHODS: Twenty-two patients who underwent transoral robotic surgery for the management of carcinoma of unknown primary were included. Patients prospectively completed the Head and Neck Cancer Inventory during a preoperative visit, and at 3-week, 3-month, 6-month, and 12-month postoperative visits. Patients' demographic, pathological, and follow-up information were also collected. AB - RESULTS: The mean follow-up time was 19.8 months. There were overall declines in all quality of life scores during treatment period, which was followed by a continuous recovery. The scores immediately after transoral robotic surgery (3 weeks) were significantly higher than the scores after conclusion of adjuvant therapy (3 months) in multiple domains (P < .05) and the 6-month scores in speech (P = .02) and eating (P = .008) domains. All scores, except for eating (P = .01) returned to pretreatment levels at 1 year. Patients with detected primaries displayed similar quality-of-life scores compared to patients with occult primaries. Human papillomavirus status and type of adjuvant treatment had no significant impact on quality of life. AB - CONCLUSIONS: Transoral robotic surgery is a promising, minimally invasive procedure for the surgical management of carcinoma of unknown primary. Patients maintain high functional and quality-of-life status at 1 year after surgery. AB - Copyright © 2014 The American Laryngological, Rhinological and Otological Society, Inc. ES - 1531-4995 IL - 0023-852X DO - https://dx.doi.org/10.1002/lary.24705 PT - Journal Article PT - Observational Study PT - Research Support, Non-U.S. Gov't ID - 24706455 [pubmed] ID - 10.1002/lary.24705 [doi] ID - PMC4266325 [pmc] ID - NIHMS646267 [mid] PP - ppublish PH - 2013/05/26 [received] PH - 2014/03/26 [revised] PH - 2014/04/02 [accepted] GI - No: P30 CA016058 Organization: (CA) *NCI NIH HHS* Country: United States LG - English EP - 20140502 DP - 2014 Sep DC - 20140826 EZ - 2014/04/08 06:00 DA - 2014/10/21 06:00 DT - 2014/04/08 06:00 YR - 2014 ED - 20141020 RD - 20161025 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24706455 <232. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24566211 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lewis C AU - Salamon C AU - Priestley JL AU - Gurshumov E AU - Culligan P FA - Lewis, Christa FA - Salamon, Charbel FA - Priestley, Jennifer L FA - Gurshumov, Emil FA - Culligan, Patrick IN - Lewis, Christa. From the *Division of Urogynecology and Reconstructive Pelvic Surgery, Atlantic Health System, Morristown, NJ; and +College of Science and Mathematics, Kennesaw State University, Kennesaw, GA. TI - Prospective cohort study of bowel function after robotic sacrocolpopexy. SO - Female Pelvic Medicine & Reconstructive Surgery. 20(2):87-9, 2014 Mar-Apr AS - Female pelvic med. reconstr. surg.. 20(2):87-9, 2014 Mar-Apr NJ - Female pelvic medicine & reconstructive surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 101528690 IO - Female Pelvic Med Reconstr Surg SB - Index Medicus CP - United States MH - Aged MH - *Defecation/ph [Physiology] MH - Female MH - *Gynecologic Surgical Procedures/ae [Adverse Effects] MH - Humans MH - Middle Aged MH - *Pelvic Organ Prolapse/su [Surgery] MH - Prospective Studies MH - Quality of Life MH - Recovery of Function MH - *Robotics MH - Surveys and Questionnaires MH - Treatment Outcome AB - OBJECTIVE: This study aimed to determine bowel function changes 12 months after robotic sacrocolpopexy. AB - METHODS: We performed a single-center prospective cohort study evaluating bowel function 12 months after robotic sacrocolpopexy between 2007 and 2011. Bowel function symptoms were measured by the Colorectal-Anal Distress Inventory, Short Form 8 (CRADI-8). Specific impacts on quality of life with regard to bowel function were evaluated using the Colorectal-Anal Impact Questionnaire, Short Form 7 (CRAIQ-7). "Splinting to defecate" was defined as any positive response to question 4 of the Pelvic Floor Distress Inventory-20 which reads, "do you ever have to push on the vagina or around the rectum to have or complete a bowel movement?." Lastly, patients were grouped according to perineorrhaphy versus no perineorrhaphy and bowel function scores were examined. AB - RESULTS: Of 423 consecutive patients who underwent robotic sacrocolpopexy at our institution, 393 (93%) completed a 12-month follow-up. Mean CRADI-8 scores at baseline and 12 months were 21.1 (20) and 7.3 (11), respectively (P < 0.0001). Mean CRAIQ-7 scores at baseline and 12 months were 11.1 (20) and 2.4 (9), respectively (P < 0.0001). Preoperatively, 152 patients reported a need to splint the vagina or perineum to complete a bowel movement. At 12 months, 70% reported complete resolution of "splinting." Con comitant perineorrhaphy was performed on 87 patients and there were no differences in 12-month CRADI-8 or CRAIQ-7 scores between groups. AB - CONCLUSIONS: Robotic sacrocolpopexy was associated with significant improvements in bowel function as measured by CRADI-8 as well as improvements in impact on quality of life as measured by CRAIQ-7. ES - 2154-4212 IL - 2151-8378 DI - 01436319-201403000-00005 DO - https://dx.doi.org/10.1097/SPV.0000000000000049 PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 24566211 [pubmed] ID - 10.1097/SPV.0000000000000049 [doi] ID - 01436319-201403000-00005 [pii] PP - ppublish LG - English DP - 2014 Mar-Apr DC - 20140225 EZ - 2014/02/26 06:00 DA - 2014/10/21 06:00 DT - 2014/02/26 06:00 YR - 2014 ED - 20141020 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24566211 <233. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24612760 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Liu X AU - Wu Y AU - Zhu J AU - Lv X AU - Tang Y AU - Sun J AU - Zhang S FA - Liu, Xiang FA - Wu, Yanhu FA - Zhu, Jinfu FA - Lv, Xiaoxia FA - Tang, Yihu FA - Sun, Jie FA - Zhang, Shijiang IN - Wu, Yanhu. Department of Cardiothoracic Surgery, First Affiliated Hospital of Nanjing Medical University, Nanjing, China. wuyanhu@njmu.edu.cn. TI - Totally thoracoscopic repair of atrial septal defect reduces systemic inflammatory reaction and myocardial damage in initial patients. SO - European Journal of Medical Research. 19:13, 2014 Mar 11 AS - Eur J Med Res. 19:13, 2014 Mar 11 NJ - European journal of medical research PI - Journal available in: Electronic PI - Citation processed from: Internet JC - coq, 9517857 IO - Eur. J. Med. Res. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995714 SB - Index Medicus CP - England MH - Adult MH - Creatine Kinase, MB Form/bl [Blood] MH - Cytokines/bl [Blood] MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - *Heart Septal Defects, Atrial/su [Surgery] MH - Humans MH - Inflammation/et [Etiology] MH - Inflammation/me [Metabolism] MH - *Inflammation MH - Male MH - Myocardium/en [Enzymology] MH - *Thoracoscopy/mt [Methods] MH - Time Factors MH - Young Adult AB - BACKGROUND: To compare the effect of totally thoracoscopic with conventional, open repair of atrial septal defect. AB - METHODS: Forty atrial septal defect cases were divided into two groups by surgical approach: totally thoracoscopic approach (group A, n=20) and conventional open approach (group B, n=20). In group A, surgical procedures were performed through three portal incisions in the right lateral chest wall under thoracoscopic vision without the aid of a computerized robotic surgical system. Notably, all operations were completed by one surgeon who had just begun using this technique. In group B, the atrial septal defects were repaired in conventional open fashion. Clinical outcomes and serum levels of tumor necrosis factor alpha (TNF-alpha), interleukin-6 (IL-6), interleukin-10 (IL-10), intercellular adhesion molecule 1 (ICAM-1), and creatine kinase isoenzyme-myocardial band (CK-MB) for the two groups were evaluated and compared. AB - RESULTS: All operations were performed successfully without serious complications. Durations of cardiopulmonary bypass (CPB), CPB setup, aortic cross-clamping, and operative procedure were significantly longer in group A than in group B (P<0.05). The recovery times for body temperature and laboratory values of leukocytes were significantly shorter for group A than for group B (P<0.05). There were no differences in durations of postoperative assisted ventilation or intensive care unit and hospital stays, volumes of blood transfused intraoperatively or thoracic drainage, or medical costs between the two groups. Serum levels of inflammatory factors (TNF-alpha, IL-6, IL-10, and ICAM-1) and CK-MB increased significantly in both groups after surgery. However, 6 h and 12 h after surgery, levels of these inflammatory factors and CK-MB were significantly lower in group A than in group B (P<0.05). AB - CONCLUSIONS: Thoracoscopic cardiac surgery is technically feasible and safe, with less trauma and quicker recovery even when done by a surgeon newly introduced to the technique. RN - 0 (Cytokines) RN - EC 2-7-3-2 (Creatine Kinase, MB Form) ES - 2047-783X IL - 0949-2321 DI - 2047-783X-19-13 DO - https://dx.doi.org/10.1186/2047-783X-19-13 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 24612760 [pubmed] ID - 2047-783X-19-13 [pii] ID - 10.1186/2047-783X-19-13 [doi] ID - PMC3995714 [pmc] PP - epublish PH - 2013/10/18 [received] PH - 2014/02/21 [accepted] LG - English EP - 20140311 DP - 2014 Mar 11 DC - 20140319 EZ - 2014/03/12 06:00 DA - 2014/10/17 06:00 DT - 2014/03/13 06:00 YR - 2014 ED - 20141016 RD - 20150515 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24612760 <234. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25069704 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hippisley-Cox J AU - Coupland C FA - Hippisley-Cox, Julia FA - Coupland, Carol IN - Hippisley-Cox, Julia. Division of Primary Care, University Park, Nottingham NG2 7RD, UK Julia.hippisley-cox@nottingham.ac.uk. IN - Coupland, Carol. Division of Primary Care, University Park, Nottingham NG2 7RD, UK. TI - Predicting risk of upper gastrointestinal bleed and intracranial bleed with anticoagulants: cohort study to derive and validate the QBleed scores. CM - Comment in: Ann Intern Med. 2014 Dec 16;161(12):JC13; PMID: 25506873 CM - Comment in: BMJ. 2014;349:g4800; PMID: 25073683 SO - BMJ. 349:g4606, 2014 Jul 28 AS - BMJ. 349:g4606, 2014 Jul 28 NJ - BMJ (Clinical research ed.) PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 8900488, bmj, 101090866 IO - BMJ PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113281 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - Adult MH - Age Distribution MH - Aged MH - Aged, 80 and over MH - Algorithms MH - *Anticoagulants/ae [Adverse Effects] MH - Epidemiologic Methods MH - Female MH - *Gastrointestinal Hemorrhage/ci [Chemically Induced] MH - Humans MH - *Intracranial Hemorrhages/ci [Chemically Induced] MH - Male MH - Middle Aged MH - Young Adult AB - OBJECTIVE: To develop and validate risk algorithms (QBleed) for estimating the absolute risk of upper gastrointestinal and intracranial bleed for patients with and without anticoagulation aged 21-99 years in primary care. AB - DESIGN: Open cohort study using routinely collected data from general practice linked to hospital episode statistics data and mortality data during the five year study period between 1 January 2008 and 1 October 2013. AB - SETTING: 565 general practices in England contributing to the national QResearch database to develop the algorithm and 188 different QResearch practices to validate the algorithm. All 753 general practices had data linked to hospital episode statistics and mortality data at individual patient level. AB - ENDPOINT: Gastrointestinal bleed and intracranial bleed recorded on either the linked mortality data or the linked hospital records. AB - PARTICIPANTS: We studied 4.4 million patients in the derivation cohort with 16.4 million person years of follow-up. During follow-up, 21,641 patients had an incident upper gastrointestinal bleed and 9040 had an intracranial bleed. For the validation cohort, we identified 1.4 million patients contributing over 4.9 million person years of follow-up. During follow-up, 6600 patients had an incident gastrointestinal bleed and 2820 had an intracranial bleed. We excluded patients without a valid Townsend score for deprivation and those prescribed anticoagulants in the 180 days before study entry. AB - RISK FACTORS: Candidate variables recorded on the general practice computer system before entry to the cohort, including personal variables (age, sex, Townsend deprivation score, ethnicity), lifestyle variables (smoking, alcohol intake), chronic diseases, prescribed drugs, clinical values (body mass index, systolic blood pressure), and laboratory test results (haemoglobin, platelets). We also included previous bleed recorded before entry to the study. AB - RESULTS: The final QBleed algorithms incorporated 21 variables. When applied to the validation cohort, the algorithms in women explained 40% of the variation for upper gastrointestinal bleed and 58% for intracranial bleed. The corresponding D statistics were 1.67 and 2.42. The receiver operating curve statistic values were 0.77 and 0.86. The sensitivity values for the top 10th of men and women at highest risk were 38% and 51%, respectively. There were similar results for men. AB - CONCLUSION: The QBleed algorithms provided valid measures of absolute risk of gastrointestinal and intracranial bleed in patients with and without anticoagulation as shown by the performance of the algorithms in a separate validation cohort. Further research is needed to evaluate the clinical outcomes and the cost effectiveness of using these algorithms in primary care. AB - Copyright © Hippisley-Cox et al 2014. RN - 0 (Anticoagulants) ES - 1756-1833 IL - 0959-535X DO - https://dx.doi.org/10.1136/bmj.g4606 PT - Journal Article PT - Validation Studies ID - 25069704 [pubmed] ID - PMC4113281 [pmc] PP - epublish LG - English EP - 20140728 DP - 2014 Jul 28 DC - 20140729 EZ - 2014/07/30 06:00 DA - 2014/10/11 06:00 DT - 2014/07/30 06:00 YR - 2014 ED - 20141010 RD - 20151026 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=25069704 <235. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23906190 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Jeong IG AU - You D AU - Yoon JH AU - Hong S AU - Lim JH AU - Hong JH AU - Choo MS AU - Ahn H AU - Kim CS FA - Jeong, In Gab FA - You, Dalsan FA - Yoon, Jong Hyun FA - Hong, Sungwoo FA - Lim, Ju Hyun FA - Hong, Jun Hyuk FA - Choo, Myung-Soo FA - Ahn, Hanjong FA - Kim, Choung-Soo IN - Jeong, In Gab. Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. TI - Impact of tamsulosin on urinary retention following early catheter removal after robot-assisted laparoscopic radical prostatectomy: a prospective randomized controlled trial. SO - International Journal of Urology. 21(2):164-8, 2014 Feb AS - Int J Urol. 21(2):164-8, 2014 Feb NJ - International journal of urology : official journal of the Japanese Urological Association PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - ce6, 9440237 IO - Int. J. Urol. SB - Index Medicus CP - Australia MH - Acute Disease MH - Aged MH - Device Removal/ae [Adverse Effects] MH - Humans MH - Laparoscopy/mt [Methods] MH - Logistic Models MH - Male MH - Middle Aged MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - Risk Assessment MH - Robotics MH - *Sulfonamides/ad [Administration & Dosage] MH - Surveys and Questionnaires MH - Treatment Outcome MH - *Urinary Catheterization MH - *Urinary Retention/dt [Drug Therapy] MH - Urinary Retention/et [Etiology] MH - Urological Agents/ad [Administration & Dosage] KW - prostatectomy; prostatic neoplasms; tamsulosin; urinary retention AB - OBJECTIVES: To examine the impact of tamsulosin on the rate of acute urinary retention following early catheter removal after robot-assisted laparoscopic radical prostatectomy. AB - METHODS: A total of 236 patients who underwent robot-assisted laparoscopic radical prostatectomy for prostate cancer carried out by a single surgeon were enrolled in this randomized study. Patients were randomly divided into two groups: treatment with tamsulosin (0.4mg) from 1 day before to 14 days after surgery (tamsulosin group), or no tamsulosin treatment (control group). The urethral catheter was removed on the fifth postoperative day. The primary end-point was the acute urinary retention rate. Changes in each domain of the International Continence Society male short-form questionnaire and uroflowmetry parameters were secondary end-points. AB - RESULTS: The primary end-point was assessed in 218 patients (92.4%; n=109 in each group). It was not assessed in 18 patients because of cystographic leak from the vesicourethral anastomosis. The acute urinary retention rate was lower in the tamsulosin group (7.3%) than in the control group (17.4%, P=0.018). Multivariate logistic regression analysis identified tamsulosin treatment and the operative experience of the surgeon as independent risk factors for acute urinary retention. Tamsulosin-treated patients had a 0.30-fold lower risk of developing acute urinary retention compared with control patients (95% confidence interval 0.12-0.76; P=0.011). None of the International Continence Society male questionnaire domain scores showed significant changes between the groups. AB - CONCLUSIONS: Perioperative treatment with tamsulosin in patients undergoing robot-assisted laparoscopic radical prostatectomy reduces the rate of acute urinary retention after early catheter removal, without aggravating urinary incontinence. AB - Copyright © 2013 The Japanese Urological Association. RN - 0 (Sulfonamides) RN - 0 (Urological Agents) RN - G3P28OML5I (tamsulosin) ES - 1442-2042 IL - 0919-8172 DO - https://dx.doi.org/10.1111/iju.12225 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 23906190 [pubmed] ID - 10.1111/iju.12225 [doi] PP - ppublish PH - 2012/11/25 [received] PH - 2013/06/03 [accepted] LG - English EP - 20130730 DP - 2014 Feb DC - 20140124 EZ - 2013/08/03 06:00 DA - 2014/10/09 06:00 DT - 2013/08/03 06:00 YR - 2014 ED - 20141008 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23906190 <236. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23913095 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Minervini A AU - Vittori G AU - Antonelli A AU - Celia A AU - Crivellaro S AU - Dente D AU - Di Santo V AU - Frea B AU - Gacci M AU - Gritti A AU - Masieri L AU - Morlacco A AU - Porreca A AU - Rocco B AU - Parma P AU - Simeone C AU - Zaramella S AU - Carini M AU - Serni S FA - Minervini, Andrea FA - Vittori, Gianni FA - Antonelli, Alessandro FA - Celia, Antonio FA - Crivellaro, Simone FA - Dente, Donato FA - Di Santo, Vincenzo FA - Frea, Bruno FA - Gacci, Mauro FA - Gritti, Alberto FA - Masieri, Lorenzo FA - Morlacco, Alessandro FA - Porreca, Angelo FA - Rocco, Bernardo FA - Parma, Paolo FA - Simeone, Claudio FA - Zaramella, Stefano FA - Carini, Marco FA - Serni, Sergio IN - Vittori, Gianni. Clinica Urologica I, Azienda Ospedaliera Careggi, Universita di Firenze, Villa Monna Tessa, Viale Pieraccini 18, 50139, Florence, Italy, giannivittori@yahoo.it. TI - Open versus robotic-assisted partial nephrectomy: a multicenter comparison study of perioperative results and complications.[Erratum appears in World J Urol. 2014 Feb;32(1):295 Note: multiple author names added] SO - World Journal of Urology. 32(1):287-93, 2014 Feb AS - World J Urol. 32(1):287-93, 2014 Feb NJ - World journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - bry, 8307716 IO - World J Urol SB - Index Medicus CP - Germany MH - Aged MH - Blood Loss, Surgical/sn [Statistics & Numerical Data] MH - Female MH - Humans MH - Incidence MH - Italy MH - *Kidney Neoplasms/su [Surgery] MH - Length of Stay/sn [Statistics & Numerical Data] MH - Longitudinal Studies MH - Male MH - Middle Aged MH - Multivariate Analysis MH - *Nephrectomy/is [Instrumentation] MH - *Nephrectomy/mt [Methods] MH - *Perioperative Period MH - *Postoperative Complications/ep [Epidemiology] MH - *Robotics MH - Treatment Outcome AB - PURPOSE: To compare surgical results, morbidity and positive surgical margins rate of patients undergoing robotic partial nephrectomy (RPN) versus open partial nephrectomy (OPN). AB - METHODS: This is an observational multicenter study promoted by the "Associazione GIovani Laparoscopisti Endoscopisti" (AGILE) no-Profit Foundation, which involved six Italian urologic centers. All clinical, surgical, and pathological variables of patients treated with OPN or RPN for renal tumors were gathered in a prospectively maintained database. Tumor nephrometry was measured with PADUA score, and complications were stratified with modified Clavien system. Differences between RPN and OPN group were assessed with univariate analysis. Perioperative variables independently associated with complications were assessed with multivariate analysis. AB - RESULTS: A total of 198 and 105 patients were enrolled in OPN and RPN group, respectively. Both had similar demographics, indications to surgery, tumor nephrometry, renal function, WIT (18.7 vs. 18.2 min; p = NS), positive margin rate (5.6 vs. 5.7%; p = NS), intraoperative complications, and postoperative medical complications. Compared to OPN, RPN group was significantly more morbid (p = 0.04), included tumors with smaller size (p = 0.002), had longer operative time (p < 0.001), lower blood loss, surgical postoperative complications (5.7 vs. 21.2%, p < 0.001), Clavien 3-4 surgical complications (1 vs. 9.1%, p = 0.001), and shorter hospitalization. The surgical approach resulted independently correlated with surgical complications on multivariate analysis. AB - CONCLUSION: In the present series, RPN was associated with a significant reduction of blood loss, surgical complications, including the reintervention rate for urinary fistula and postoperative bleeding, and with a shorter hospitalization. ES - 1433-8726 IL - 0724-4983 DO - https://dx.doi.org/10.1007/s00345-013-1136-x PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Observational Study ID - 23913095 [pubmed] ID - 10.1007/s00345-013-1136-x [doi] PP - ppublish PH - 2013/04/01 [received] PH - 2013/07/20 [accepted] LG - English EP - 20130804 DP - 2014 Feb DC - 20140127 EZ - 2013/08/06 06:00 DA - 2014/10/07 06:00 DT - 2013/08/06 06:00 YR - 2014 ED - 20141006 RD - 20140127 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23913095 <237. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24885669 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Randell R AU - Greenhalgh J AU - Hindmarsh J AU - Dowding D AU - Jayne D AU - Pearman A AU - Gardner P AU - Croft J AU - Kotze A FA - Randell, Rebecca FA - Greenhalgh, Joanne FA - Hindmarsh, Jon FA - Dowding, Dawn FA - Jayne, David FA - Pearman, Alan FA - Gardner, Peter FA - Croft, Julie FA - Kotze, Alwyn IN - Randell, Rebecca. School of Healthcare, Baines Wing, University of Leeds, Leeds LS2 9JT, UK. r.randell@leeds.ac.uk. TI - Integration of robotic surgery into routine practice and impacts on communication, collaboration, and decision making: a realist process evaluation protocol. SO - Implementation Science. 9:52, 2014 May 02 AS - Implement Sci. 9:52, 2014 May 02 NJ - Implementation science : IS PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101258411 IO - Implement Sci PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017969 SB - Index Medicus CP - England MH - *Communication MH - *Cooperative Behavior MH - Evidence-Based Medicine MH - Humans MH - Interviews as Topic MH - Laparoscopy/mt [Methods] MH - Rectal Neoplasms/su [Surgery] MH - Research Design MH - *Robotics MH - *Surgical Procedures, Operative/mt [Methods] MH - Videotape Recording AB - BACKGROUND: Robotic surgery offers many potential benefits for patients. While an increasing number of healthcare providers are purchasing surgical robots, there are reports that the technology is failing to be introduced into routine practice. Additionally, in robotic surgery, the surgeon is physically separated from the patient and the rest of the team, with the potential to negatively impact teamwork in the operating theatre. The aim of this study is to ascertain: how and under what circumstances robotic surgery is effectively introduced into routine practice; and how and under what circumstances robotic surgery impacts teamwork, communication and decision making, and subsequent patient outcomes. AB - METHODS AND DESIGN: We will undertake a process evaluation alongside a randomised controlled trial comparing laparoscopic and robotic surgery for the curative treatment of rectal cancer. Realist evaluation provides an overall framework for the study. The study will be in three phases. In Phase I, grey literature will be reviewed to identify stakeholders' theories concerning how robotic surgery becomes embedded into surgical practice and its impacts. These theories will be refined and added to through interviews conducted across English hospitals that are using robotic surgery for rectal cancer resection with staff at different levels of the organisation, along with a review of documentation associated with the introduction of robotic surgery. In Phase II, a multi-site case study will be conducted across four English hospitals to test and refine the candidate theories. Data will be collected using multiple methods: the structured observation tool OTAS (Observational Teamwork Assessment for Surgery); video recordings of operations; ethnographic observation; and interviews. In Phase III, interviews will be conducted at the four case sites with staff representing a range of surgical disciplines, to assess the extent to which the results of Phase II are generalisable and to refine the resulting theories to reflect the experience of a broader range of surgical disciplines. The study will provide (i) guidance to healthcare organisations on factors likely to facilitate successful implementation and integration of robotic surgery, and (ii) guidance on how to ensure effective communication and teamwork when undertaking robotic surgery. ES - 1748-5908 IL - 1748-5908 DI - 1748-5908-9-52 DO - https://dx.doi.org/10.1186/1748-5908-9-52 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 24885669 [pubmed] ID - 1748-5908-9-52 [pii] ID - 10.1186/1748-5908-9-52 [doi] ID - PMC4017969 [pmc] PP - epublish PH - 2014/03/07 [received] PH - 2014/04/29 [accepted] GI - No: HS&DR/12/5005/04 Organization: *Department of Health* Country: United Kingdom LG - English EP - 20140502 DP - 2014 May 02 DC - 20140604 EZ - 2014/06/03 06:00 DA - 2014/09/30 06:00 DT - 2014/06/03 06:00 YR - 2014 ED - 20140929 RD - 20150805 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24885669 <238. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24581993 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Khatib M AU - Hald N AU - Brenton H AU - Barakat MF AU - Sarker SK AU - Standfield N AU - Ziprin P AU - Kneebone R AU - Bello F FA - Khatib, Manaf FA - Hald, Niels FA - Brenton, Harry FA - Barakat, Mohamad Fahed FA - Sarker, Sudip K FA - Standfield, Nigel FA - Ziprin, Paul FA - Kneebone, Roger FA - Bello, Fernando IN - Khatib, Manaf. Department of Surgery and Cancer, Imperial College London, UK. Electronic address: manaf_khatib@hotmail.com. IN - Hald, Niels. Department of Surgery and Cancer, Imperial College London, UK. IN - Brenton, Harry. Department of Surgery and Cancer, Imperial College London, UK. IN - Barakat, Mohamad Fahed. Department of Surgery and Cancer, Imperial College London, UK. IN - Sarker, Sudip K. Department of General Surgery, Worcestershire Royal Hospital, UK. IN - Standfield, Nigel. Department of Surgery and Cancer, Imperial College London, UK; The London Deanery, UK. IN - Ziprin, Paul. Department of Surgery and Cancer, Imperial College London, UK. IN - Kneebone, Roger. Department of Surgery and Cancer, Imperial College London, UK. IN - Bello, Fernando. Department of Surgery and Cancer, Imperial College London, UK. TI - Validation of open inguinal hernia repair simulation model: a randomized controlled educational trial. SO - American Journal of Surgery. 208(2):295-301, 2014 Aug AS - Am J Surg. 208(2):295-301, 2014 Aug NJ - American journal of surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 3z4, 0370473 IO - Am. J. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - *Clinical Competence MH - *Computer Simulation MH - *General Surgery/ed [Education] MH - *Hernia, Inguinal/su [Surgery] MH - Humans MH - Students, Medical MH - *Teaching/mt [Methods] KW - Hernia repair; Randomized controlled educational trial; Surgical education; Surgical simulation AB - BACKGROUND: A hernia repair open surgical simulation computer software was developed at Imperial College London. A randomized controlled educational trial was conducted to investigate the benefit of the simulation on the development of procedural knowledge. AB - METHODS: Medical students in their clinical years were invited to participate in the trial. Students were block randomized to 4 groups: G1--Interactive Simulation; G2--Non-interactive Simulation; G3--Video Tutorial; G4--Control. On completion, they were objectively assessed on their ability to recall the tasks involved in an open inguinal hernia repair in the form of a multiple choice question (MCQ) and a simulated discussion with a consultant surgeon. AB - RESULTS: Fifty-six students completed the study. Each arm carries similar baseline scores (pre-intervention MCQ) with means 43.33, 38.92, 38.33, and 39.57 in G1 to G4, respectively. MCQ score improvements and final assessment scores proved better in the intervention groups (1, 2, and 3) compared to controls. AB - CONCLUSION: The interactive simulation has shown an objective benefit in teaching medical students the anatomical and procedural knowledge in performing an open inguinal hernia repair. AB - Copyright © 2014 Elsevier Inc. All rights reserved. ES - 1879-1883 IL - 0002-9610 DI - S0002-9610(14)00038-5 DO - https://dx.doi.org/10.1016/j.amjsurg.2013.12.007 PT - Journal Article PT - Randomized Controlled Trial ID - 24581993 [pubmed] ID - S0002-9610(14)00038-5 [pii] ID - 10.1016/j.amjsurg.2013.12.007 [doi] PP - ppublish PH - 2013/10/02 [received] PH - 2013/11/25 [revised] PH - 2013/12/07 [accepted] LG - English EP - 20140124 DP - 2014 Aug DC - 20140728 EZ - 2014/03/04 06:00 DA - 2014/09/30 06:00 DT - 2014/03/04 06:00 YR - 2014 ED - 20140929 RD - 20140728 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24581993 <239. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24758776 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Perniola A AU - Magnuson A AU - Axelsson K AU - Gupta A FA - Perniola, Andrea FA - Magnuson, Anders FA - Axelsson, Kjell FA - Gupta, Anil IN - Perniola, Andrea. From the Department of Anesthesiology and Intensive Care (A.P., K.A., A.G.), and Clinical Epidemiology and Biostatistical Unit, Clinical Research Center (A.M.), Orebro University Hospital, School of Health and Medical Sciences, Orebro University, Orebro, Sweden. TI - Intraperitoneal local anesthetics have predominant local analgesic effect: a randomized, double-blind study. SO - Anesthesiology. 121(2):352-61, 2014 Aug AS - Anesthesiology. 121(2):352-61, 2014 Aug NJ - Anesthesiology PI - Journal available in: Print PI - Citation processed from: Internet JC - 4sg, 1300217 IO - Anesthesiology SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Analgesia, Patient-Controlled MH - Analgesics, Opioid/ad [Administration & Dosage] MH - Analgesics, Opioid/tu [Therapeutic Use] MH - Anesthesia, General MH - *Anesthesia, Local MH - *Anesthetics, Local/ad [Administration & Dosage] MH - Anesthetics, Local/bl [Blood] MH - *Anesthetics, Local/pd [Pharmacology] MH - Anti-Inflammatory Agents, Non-Steroidal/ad [Administration & Dosage] MH - Anti-Inflammatory Agents, Non-Steroidal/tu [Therapeutic Use] MH - Double-Blind Method MH - Endpoint Determination MH - Female MH - Fentanyl/ad [Administration & Dosage] MH - Fentanyl/tu [Therapeutic Use] MH - Humans MH - Hysterectomy/ae [Adverse Effects] MH - Injections, Intraperitoneal MH - Injections, Intravenous MH - Lidocaine/ad [Administration & Dosage] MH - Lidocaine/bl [Blood] MH - Lidocaine/pd [Pharmacology] MH - Middle Aged MH - Morphine/ad [Administration & Dosage] MH - Morphine/tu [Therapeutic Use] MH - Pain Measurement/de [Drug Effects] MH - Pain, Postoperative/dt [Drug Therapy] MH - Prospective Studies AB - BACKGROUND: It remains unclear whether analgesia from intraperitoneal local anesthetics is via local or central mechanisms. This double-blind clinical trial tests the hypothesis that intraperitoneal local anesthetic is superior to continuous IV infusion for pain management. Primary outcome was morphine consumption during 0 to 24 h. AB - METHODS: Informed consent was obtained from 60 patients, age 30 to 75 yr, American Society of Anesthesiologists physical status I to II, undergoing abdominal hysterectomy. A computer-generated program randomized patients in parallel arms to group IV: continuous infusion of lidocaine 50 mg/h (10 ml) IV and saline 10 ml/h intermittently intraperitoneal; group IP: injection of lidocaine 50 mg/h (10 ml) once every hour intraperitoneally and continuous infusion of saline 10 ml/h intravenously; and group P (placebo): saline 10 ml/h both intravenously and intermittent intraperitoneal injection. Postoperative morphine consumption, pain intensity, recovery, home discharge, and lidocaine concentrations were measured. AB - RESULTS: Morphine consumption during 0 to 24 h was lower in group IP versus group IV, mean difference -22.6 mg (95% CI, 11.4 to 33.8; P < 0.01). No difference was seen between group IV and group P. The total mean plasma concentration of lidocaine in group IP was significantly lower than group IV, 0 to 4.5 h postoperatively (P = 0.03) with no evidence of systemic toxicity. Pain intensity and other recovery parameters were similar between the groups. AB - CONCLUSION: The lower supplemental morphine consumption and plasma lidocaine concentration in group IP would confirm that the effects of local anesthetics are likely to be predominant via local intraperitoneal receptors or anti-inflammatory effects and not via central mechanisms alone. RN - 0 (Analgesics, Opioid) RN - 0 (Anesthetics, Local) RN - 0 (Anti-Inflammatory Agents, Non-Steroidal) RN - 76I7G6D29C (Morphine) RN - 98PI200987 (Lidocaine) RN - UF599785JZ (Fentanyl) ES - 1528-1175 IL - 0003-3022 DO - https://dx.doi.org/10.1097/ALN.0000000000000267 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 24758776 [pubmed] ID - 10.1097/ALN.0000000000000267 [doi] PP - ppublish LG - English DP - 2014 Aug DC - 20140724 EZ - 2014/04/25 06:00 DA - 2014/09/11 06:00 DT - 2014/04/25 06:00 YR - 2014 ED - 20140910 RD - 20140724 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24758776 <240. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24646165 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Parekh S AU - King D AU - Boyle FM AU - Vandelanotte C FA - Parekh, Sanjoti FA - King, David FA - Boyle, Frances M FA - Vandelanotte, Corneel IN - Parekh, Sanjoti. School of Population Health, The University of Queensland, Herston, Queensland 4006, Australia. s.parekh@uq.edu.au. TI - Randomized controlled trial of a computer-tailored multiple health behaviour intervention in general practice: 12-month follow-up results. SO - International Journal of Behavioral Nutrition & Physical Activity. 11(1):41, 2014 Mar 19 AS - Int. j. behav. nutr. phys. act.. 11(1):41, 2014 Mar 19 NJ - The international journal of behavioral nutrition and physical activity PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101217089 IO - Int J Behav Nutr Phys Act PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995078 SB - Index Medicus CP - England MH - Adolescent MH - Adult MH - Australia MH - Diet MH - *Feeding Behavior MH - Female MH - Follow-Up Studies MH - Fruit MH - General Practice MH - *Health Behavior MH - Health Care Costs MH - *Health Promotion MH - Humans MH - Life Style MH - Male MH - Middle Aged MH - Motor Activity MH - Risk Factors MH - Surveys and Questionnaires MH - Vegetables MH - Young Adult AB - BACKGROUND: Effective strategies to address risk factors of non-communicable diseases are required to curtail the expanding costs of health care. This trial tested the effectiveness over one year of a minimal intervention targeting multiple health behaviours (diet, physical activity, alcohol and smoking) in a general practice setting, through the provision of personalised, computer-tailored feedback. AB - METHODS: Patients who had attended a general practice in the previous 6 months were recruited from 21 general practitioners in Brisbane, Australia. Baseline data were collected using self-reports on adherence to ten health behaviours and summarised into a health score from 0 to 10. This randomised controlled trial used a 2x2 factorial design, with one arm randomising subjects to the intervention or control group. The other arm was either feedback at baseline (single contact) or an additional assessment with feedback at 3 months (dual contact). As such, 4 study groups created were, to which participants were randomised blindly: A. Intervention with single contact; B. Intervention with dual contact; C. Control with single contact and D. Control with dual contact. All participants were assessed again at 12 months. AB - RESULTS: Of the 4676 participants randomised, 3065 completed questionnaires at 12 months. Both single and dual contact groups improved their 10 item health scores (+0.31 and +0.49 respectively) relative to control group outcomes (+0.02; p<0.01). Improvement in adherence to guidelines for fish intake, type of milk consumed, vegetable and fruit intake, and alcohol intake were observed in single and dual contact intervention groups (p<0.01). Both intervention groups showed greater improvement than controls for individual health behaviours, apart from red meat intake, smoking behaviour, physical activity and body weight. Interestingly, there was an improvement in reported non-smoking rates in both intervention and control groups (3% single contact; 4.5% dual contact). AB - CONCLUSIONS: Small but meaningful long-term changes in health behaviours can be achieved with a low-intensity intervention, which may reduce health care costs if implemented on a large scale. Further research is needed to better understand the mechanism by which maintenance of behaviour change can be achieved. AB - TRIAL REGISTRATION: The Australian New Zealand Clinical Trials Registry: ACTRN12611001213932. ES - 1479-5868 IL - 1479-5868 DI - 1479-5868-11-41 DO - https://dx.doi.org/10.1186/1479-5868-11-41 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 24646165 [pubmed] ID - 1479-5868-11-41 [pii] ID - 10.1186/1479-5868-11-41 [doi] ID - PMC3995078 [pmc] PP - epublish PH - 2013/07/10 [received] PH - 2014/03/10 [accepted] LG - English EP - 20140319 DP - 2014 Mar 19 DC - 20140326 EZ - 2014/03/21 06:00 DA - 2014/09/11 06:00 DT - 2014/03/22 06:00 YR - 2014 ED - 20140910 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24646165 <241. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24368486 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Nosti PA AU - Umoh Andy U AU - Kane S AU - White DE AU - Harvie HS AU - Lowenstein L AU - Gutman RE FA - Nosti, Patrick A FA - Umoh Andy, Uduak FA - Kane, Sarah FA - White, Dena E FA - Harvie, Heidi S FA - Lowenstein, Lior FA - Gutman, Robert E IN - Nosti, Patrick A. From the *FPMRS Division, Obstetrics and Gynecology Department, Medstar Washington Hospital Center, Georgetown University School of Medicine, Washington, DC; +FPMRS Division, Obstetrics and Gynecology Department, University of Pennsylvania, Philadelphia, PA; ++Division of Urogynecology, Obstetrics and Gynecology Department, Case Western Reserve University, MetroHealth Medical Center; FPMRS Division, Obstetrics and Gynecology Department, University of Oklahoma, Oklahoma City, OK; and FPMRS Division, Obstetrics and Gynecology Department, Rambam Health Care Campus, Haifa, Israel. TI - Outcomes of abdominal and minimally invasive sacrocolpopexy: a retrospective cohort study. SO - Female Pelvic Medicine & Reconstructive Surgery. 20(1):33-7, 2014 Jan-Feb AS - Female pelvic med. reconstr. surg.. 20(1):33-7, 2014 Jan-Feb NJ - Female pelvic medicine & reconstructive surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 101528690 IO - Female Pelvic Med Reconstr Surg SB - Index Medicus CP - United States MH - Abdomen/su [Surgery] MH - Aged MH - Female MH - *Gynecologic Surgical Procedures/ae [Adverse Effects] MH - Gynecologic Surgical Procedures/mt [Methods] MH - Humans MH - *Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/mt [Methods] MH - Middle Aged MH - *Minimally Invasive Surgical Procedures/ae [Adverse Effects] MH - Minimally Invasive Surgical Procedures/mt [Methods] MH - *Postoperative Complications/et [Etiology] MH - Retrospective Studies MH - Robotics MH - Sacrococcygeal Region/su [Surgery] MH - Treatment Outcome AB - OBJECTIVE: To compare perioperative and postoperative surgical outcomes between and among open and minimally invasive sacrocolpopexies (MISCs). AB - METHODS: We performed a multicenter retrospective cohort study comparing abdominal sacrocolpopexy (ASC) and MISC from January 1999 to December 2010. AB - RESULTS: A total of 1124 subjects underwent sacrocolpopexy, with 589 ASCs and 535 MISCs. Within the MISC group, 273 were laparoscopic (LSC) and 262 were robotic (RSC). Abdominal sacrocolpopexy was associated with greater overall complication rate compared with MISC (20.0% vs 12.7%; P = 0.001). After controlling for difference in length of follow-up, there was no significant difference in the rate of anatomical failure between the ASC and MISC groups. The MISC group had shorter hospitalization, less blood loss, but longer operative times compared with the ASC group. When comparing LSC to RSC, there was no difference in anatomic failures (7.7% vs 6.9%; P = 0.74). However, LSC was associated with more complications compared with RSC (18% vs 7%; P < 0.02). In addition, LSC had higher blood loss, less operative time, and shorter hospital stay compared with RSC. AB - CONCLUSION: Although anatomic results are similar, ASC is associated with a higher rate of complications compared with MISC. ES - 2154-4212 IL - 2151-8378 DI - 01436319-201401000-00007 DO - https://dx.doi.org/10.1097/SPV.0000000000000036 PT - Comparative Study PT - Journal Article PT - Multicenter Study ID - 24368486 [pubmed] ID - 10.1097/SPV.0000000000000036 [doi] ID - 01436319-201401000-00007 [pii] PP - ppublish LG - English DP - 2014 Jan-Feb DC - 20131225 EZ - 2013/12/26 06:00 DA - 2014/09/10 06:00 DT - 2013/12/26 06:00 YR - 2014 ED - 20140908 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24368486 <242. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24225725 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Closhen D AU - Treiber AH AU - Berres M AU - Sebastiani A AU - Werner C AU - Engelhard K AU - Schramm P FA - Closhen, Dorothea FA - Treiber, Adrian-Hennig FA - Berres, Manfred FA - Sebastiani, Anne FA - Werner, Christian FA - Engelhard, Kristin FA - Schramm, Patrick IN - Closhen, Dorothea. From the Department of Anaesthesiology (DC, A-HT, AS, CW, KE, PS); Institute of Medical Biometry, Epidemiology and Informatics (IMBEI), University Medical Centre of the Johannes Gutenberg-University Mainz, Mainz (MB); Department of Mathematics and Technology, RheinAhrCampus, Remagen, Germany (MB). TI - Robotic assisted prostatic surgery in the Trendelenburg position does not impair cerebral oxygenation measured using two different monitors: A clinical observational study. SO - European Journal of Anaesthesiology. 31(2):104-9, 2014 Feb AS - Eur J Anaesthesiol. 31(2):104-9, 2014 Feb NJ - European journal of anaesthesiology PI - Journal available in: Print PI - Citation processed from: Internet JC - ems, 8411711 IO - Eur J Anaesthesiol SB - Index Medicus CP - England MH - Aged MH - Anesthesia/mt [Methods] MH - *Brain/pa [Pathology] MH - Carbon Dioxide/ch [Chemistry] MH - Cerebrovascular Circulation MH - Frontal Lobe/pa [Pathology] MH - *Head-Down Tilt MH - Humans MH - Male MH - Middle Aged MH - Monitoring, Physiologic/mt [Methods] MH - Oxygen/bl [Blood] MH - Patient Positioning MH - Perfusion MH - Pneumoperitoneum, Artificial MH - *Prostate/su [Surgery] MH - *Prostatectomy/mt [Methods] MH - Robotics/mt [Methods] MH - Spectroscopy, Near-Infrared AB - BACKGROUND: Robotic assisted prostatic surgery is frequently used because of its reduced side-effects compared with conventional surgery. During surgery, an extreme Trendelenburg position and CO2 pneumoperitoneum are necessary, which may lead to cerebral oedema, can potentially reduce brain perfusion and therefore could impair cerebral oxygenation. Cerebral oxygen saturation can be measured non-invasively using near-infrared spectroscopy (NIRS). AB - OBJECTIVE: The hypothesis of the present study was that steep Trendelenburg positioning during robotic assisted prostatic surgery impairs cerebral oxygen saturation measured using two different NIRS monitors. AB - DESIGN: Clinical observational study. AB - SETTING: Primary care university hospital, study period from March 2012 to February 2013. AB - PATIENTS: A total of 29 patients scheduled for robotic assisted prostatic surgery in a steep Trendelenburg position. AB - INTERVENTIONS: Cerebral oxygen saturation was measured throughout anaesthesia using the INVOS sensor (a trend monitor using two infrared wavelengths) for one hemisphere and the FORE-SIGHT sensor (a monitor using four wavelengths of laser light to calculate absolute oxygen saturation) for the other hemisphere in an alternate randomisation. AB - MAIN OUTCOME MEASURE: Changes in cerebral oxygenation of more than 5% during surgery in the Trendelenburg position. AB - RESULTS: The median duration of Trendelenburg positioning was 190 (interquartile range 130 to 230) min. Cerebral oxygen saturation decreased with INVOS from 74 +/- 5% at baseline to a lowest value of 70 +/- 4% with a slope of -0.0129 min(-1) (P < 0.01) and with FORE-SIGHT from 72 +/- 5% at baseline to a nadir of 70 +/- 3% with a slope of -0.008 min(-1) (P < 0.01). Comparing INVOS with FORE-SIGHT, there was a good association, with a slope of 0.86 +/- 0.04 (P < 0.01). AB - CONCLUSION: Both monitors showed a clinically irrelevant decrease in cerebral oxygen saturation of less than 5% over 4 h in a steep Trendelenburg position combined with CO2 pneumoperitoneum in patients undergoing robotic assisted prostatic surgery. This extreme positioning seems to be acceptable with regard to cerebral oxygenation. AB - TRIAL REGISTRATION: clinicaltrials.gov Identifier: ID NCT01275898. RN - 142M471B3J (Carbon Dioxide) RN - S88TT14065 (Oxygen) ES - 1365-2346 IL - 0265-0215 DO - https://dx.doi.org/10.1097/EJA.0000000000000000 PT - Journal Article PT - Observational Study PT - Research Support, Non-U.S. Gov't ID - 24225725 [pubmed] ID - 10.1097/EJA.0000000000000000 [doi] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01275898 SL - https://clinicaltrials.gov/search/term=NCT01275898 LG - English DP - 2014 Feb DC - 20131227 EZ - 2013/11/15 06:00 DA - 2014/09/04 06:00 DT - 2013/11/15 06:00 YR - 2014 ED - 20140903 RD - 20131227 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24225725 <243. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24857271 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hughes-Hallett A AU - Pratt P AU - Mayer E AU - Martin S AU - Darzi A AU - Vale J FA - Hughes-Hallett, Archie FA - Pratt, Philip FA - Mayer, Erik FA - Martin, Shirley FA - Darzi, Ara FA - Vale, Justin IN - Hughes-Hallett, Archie. Department of Surgery and Cancer, Imperial College London, London, United Kingdom. IN - Pratt, Philip. Hamlyn Centre for Robotic Surgery, Imperial College London, London, United Kingdom. IN - Mayer, Erik. Department of Surgery and Cancer, Imperial College London, London, United Kingdom. Electronic address: e.mayer@imperial.ac.uk. IN - Martin, Shirley. Imperial College Healthcare NHS Trust, London, United Kingdom. IN - Darzi, Ara. Department of Surgery and Cancer, Imperial College London, London, United Kingdom; Hamlyn Centre for Robotic Surgery, Imperial College London, London, United Kingdom. IN - Vale, Justin. Department of Surgery and Cancer, Imperial College London, London, United Kingdom. TI - Image guidance for all--TilePro display of 3-dimensionally reconstructed images in robotic partial nephrectomy. CM - Comment in: Urology. 2014 Jul;84(1):243; PMID: 24857269 CM - Comment in: Urology. 2014 Jul;84(1):242-3; PMID: 24857273 SO - Urology. 84(1):237-42, 2014 Jul AS - Urology. 84(1):237-42, 2014 Jul NJ - Urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Cross-Over Studies MH - Humans MH - *Imaging, Three-Dimensional MH - *Nephrectomy/mt [Methods] MH - *Robotics MH - *Software MH - *Surgery, Computer-Assisted AB - OBJECTIVE: To determine the feasibility of a novel low-barrier-to-entry image guidance system. AB - METHODS: Initially a randomized crossover study was performed to establish the interface (iPad or 3-dimensional mouse) that minimized both the amount of time required to perform a manual image registration and the error of that registration. A subsequent clinical feasibility study was undertaken on 5 patients undergoing robot-assisted partial nephrectomy. Randomized crossover study primary outcomes were time to task completion, NASA-Task Load Index score, and alignment error (translational and rotational). The Mann-Whitney U test was used to compare groups. Surgeon feedback was sought when assessing the system in a clinical setting. AB - RESULTS: In the initial randomized crossover study, the iPad-based system was able to achieve adequate alignment accuracy (Frobenius norm of 0.3; total error of 20.8 mm) in significantly less time (33 seconds; P<.01) than the 3-dimensional mouse interface. The platform received good feedback from the operating surgeon in all instances with the surgeon commenting particularly on the improved appreciation of hilar vascular anatomy. AB - CONCLUSION: In this study, we have demonstrated the feasibility of a "low-barrier-to-entry" image guidance system in a clinical setting. The system was able to achieve swift and sufficiently accurate alignment, with little impact on the surgical workflow. AB - Copyright © 2014 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(14)00340-9 DO - https://dx.doi.org/10.1016/j.urology.2014.02.051 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 24857271 [pubmed] ID - S0090-4295(14)00340-9 [pii] ID - 10.1016/j.urology.2014.02.051 [doi] PP - ppublish PH - 2013/11/06 [received] PH - 2014/01/02 [revised] PH - 2014/02/08 [accepted] LG - English EP - 20140522 DP - 2014 Jul DC - 20140630 EZ - 2014/05/27 06:00 DA - 2014/09/02 06:00 DT - 2014/05/27 06:00 YR - 2014 ED - 20140901 RD - 20150708 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24857271 <244. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24239530 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Casillas MA Jr AU - Leichtle SW AU - Wahl WL AU - Lampman RM AU - Welch KB AU - Wellock T AU - Madden EB AU - Cleary RK FA - Casillas, Mark A Jr FA - Leichtle, Stefan W FA - Wahl, Wendy L FA - Lampman, Richard M FA - Welch, Kathleen B FA - Wellock, Trisha FA - Madden, Erin B FA - Cleary, Robert K IN - Casillas, Mark A Jr. Department of Surgery, Division of Colon and Rectal Surgery, Saint Joseph Mercy Health System, 5325 Elliott Drive, Suite 104, Ann Arbor, MI, USA. IN - Leichtle, Stefan W. Department of Surgery, Division of Colon and Rectal Surgery, Saint Joseph Mercy Health System, 5325 Elliott Drive, Suite 104, Ann Arbor, MI, USA. IN - Wahl, Wendy L. Department of Surgery, Division of Colon and Rectal Surgery, Saint Joseph Mercy Health System, 5325 Elliott Drive, Suite 104, Ann Arbor, MI, USA. IN - Lampman, Richard M. Department of Surgery, Division of Colon and Rectal Surgery, Saint Joseph Mercy Health System, 5325 Elliott Drive, Suite 104, Ann Arbor, MI, USA. IN - Welch, Kathleen B. Center for Statistical Consultation & Research, University of Michigan, Ann Arbor, MI, USA. IN - Wellock, Trisha. Department of Surgery, Division of Colon and Rectal Surgery, Saint Joseph Mercy Health System, 5325 Elliott Drive, Suite 104, Ann Arbor, MI, USA. IN - Madden, Erin B. Department of Surgery, Division of Colon and Rectal Surgery, Saint Joseph Mercy Health System, 5325 Elliott Drive, Suite 104, Ann Arbor, MI, USA. IN - Cleary, Robert K. Department of Surgery, Division of Colon and Rectal Surgery, Saint Joseph Mercy Health System, 5325 Elliott Drive, Suite 104, Ann Arbor, MI, USA. Electronic address: clearyrk@trinity-health.org. TI - Improved perioperative and short-term outcomes of robotic versus conventional laparoscopic colorectal operations. SO - American Journal of Surgery. 208(1):33-40, 2014 Jul AS - Am J Surg. 208(1):33-40, 2014 Jul NJ - American journal of surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 3z4, 0370473 IO - Am. J. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - *Colectomy/mt [Methods] MH - *Colonic Diseases/su [Surgery] MH - Female MH - Humans MH - *Laparoscopy MH - Length of Stay MH - Male MH - Middle Aged MH - Operative Time MH - Postoperative Complications/et [Etiology] MH - Propensity Score MH - Prospective Studies MH - *Rectal Diseases/su [Surgery] MH - *Rectum/su [Surgery] MH - Regression Analysis MH - *Robotics MH - Treatment Outcome KW - 30-day outcomes; Colectomy; Laparoscopic colorectal surgery; Robotic surgery AB - BACKGROUND: Robotic assistance may offer unique advantages over conventional laparoscopy in colorectal operations. AB - METHODS: This prospective observational study compared operative measures and postoperative outcomes between laparoscopic and robotic abdominal and pelvic resections for benign and malignant disease. AB - RESULTS: From 2005 through 2012, 200 (58%) laparoscopic and 144 (42%) robotic operations were performed by a single surgeon. After adjustment for differences in demographics and disease processes using propensity score matching, all laparoscopic operations had a significantly shorter operative time (P < .01), laparoscopic left colectomies had a longer length of hospital stay (2009 and 2010: 6.5 vs 3.6 days, P = .01); and laparoscopic right colectomies had a higher risk for overall complications (P = .03) and postoperative ileus (P = .04). There were no significant differences in the outcomes of pelvic operations (P = .15). AB - CONCLUSIONS: Compared with conventional laparoscopy, some types of robotic-assisted colorectal operations may offer advantages regarding postoperative length of stay and perioperative complications. AB - Copyright © 2014 Elsevier Inc. All rights reserved. ES - 1879-1883 IL - 0002-9610 DI - S0002-9610(13)00608-9 DO - https://dx.doi.org/10.1016/j.amjsurg.2013.08.028 PT - Comparative Study PT - Journal Article PT - Observational Study ID - 24239530 [pubmed] ID - S0002-9610(13)00608-9 [pii] ID - 10.1016/j.amjsurg.2013.08.028 [doi] PP - ppublish PH - 2013/02/24 [received] PH - 2013/07/20 [revised] PH - 2013/08/09 [accepted] LG - English EP - 20131023 DP - 2014 Jul DC - 20140621 EZ - 2013/11/19 06:00 DA - 2014/08/26 06:00 DT - 2013/11/19 06:00 YR - 2014 ED - 20140825 RD - 20140621 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24239530 <245. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24215940 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Gardiner RA AU - Coughlin GD AU - Yaxley JW AU - Dunglison NT AU - Occhipinti S AU - Younie SJ AU - Carter RC AU - Williams SG AU - Medcraft RJ AU - Samaratunga HM AU - Perry-Keene JL AU - Payton DJ AU - Lavin MF AU - Chambers SK FA - Gardiner, Robert A FA - Coughlin, Geoffrey D FA - Yaxley, John W FA - Dunglison, Nigel T FA - Occhipinti, Stefano FA - Younie, Sandra J FA - Carter, Rob C FA - Williams, Scott G FA - Medcraft, Robyn J FA - Samaratunga, Hema M FA - Perry-Keene, Joanna L FA - Payton, Diane J FA - Lavin, Martin F FA - Chambers, Suzanne K IN - Gardiner, Robert A. The University of Queensland Centre for Clinical Research, Brisbane, Australia; Department of Urology, Royal Brisbane & Women's Hospital, Brisbane, Australia; Edith Cowan University, Perth, Australia. Electronic address: f.gardiner@uq.edu.au. IN - Coughlin, Geoffrey D. Department of Urology, Royal Brisbane & Women's Hospital, Brisbane, Australia. IN - Yaxley, John W. Department of Urology, Royal Brisbane & Women's Hospital, Brisbane, Australia. IN - Dunglison, Nigel T. Department of Urology, Royal Brisbane & Women's Hospital, Brisbane, Australia. IN - Occhipinti, Stefano. Griffith University, Brisbane, Australia. IN - Younie, Sandra J. Deakin University, Melbourne, Australia. IN - Carter, Rob C. Deakin University, Melbourne, Australia. IN - Williams, Scott G. Peter Macallum Cancer Centre, Melbourne, Australia. IN - Medcraft, Robyn J. The University of Queensland Centre for Clinical Research, Brisbane, Australia. IN - Samaratunga, Hema M. Aquesta Pathology, Brisbane, Australia. IN - Perry-Keene, Joanna L. Anatomical Pathology, Pathology Queensland, Brisbane, Australia. IN - Payton, Diane J. Anatomical Pathology, Pathology Queensland, Brisbane, Australia. IN - Lavin, Martin F. The University of Queensland Centre for Clinical Research, Brisbane, Australia; Queensland Institute of Medical Research, Brisbane, Australia. IN - Chambers, Suzanne K. The University of Queensland Centre for Clinical Research, Brisbane, Australia; Edith Cowan University, Perth, Australia; Griffith University, Brisbane, Australia; Cancer Council Queensland, Brisbane, Australia; Prostate Cancer Foundation of Australia, Brisbane, Australia. TI - A progress report on a prospective randomised trial of open and robotic prostatectomy. SO - European Urology. 65(3):512-5, 2014 Mar AS - Eur Urol. 65(3):512-5, 2014 Mar NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Humans MH - Male MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - Queensland MH - Research Report MH - *Robotics AB - A randomised trial of robotic and open prostatectomy commenced in October 2010 and is progressing well. Clinical and quality of life outcomes together with economic costs to individuals and the health service are being examined critically to compare outcomes. AB - Crown Copyright © 2013. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(13)01104-4 DO - https://dx.doi.org/10.1016/j.eururo.2013.10.031 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 24215940 [pubmed] ID - S0302-2838(13)01104-4 [pii] ID - 10.1016/j.eururo.2013.10.031 [doi] PP - ppublish PH - 2013/10/09 [received] PH - 2013/10/21 [accepted] LG - English EP - 20131031 DP - 2014 Mar DC - 20140131 EZ - 2013/11/13 06:00 DA - 2014/08/21 06:00 DT - 2013/11/13 06:00 YR - 2014 ED - 20140820 RD - 20140131 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24215940 <246. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25132891 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - PubMed-not-MEDLINE AU - Oh JJ AU - Byun S AU - Hong SK AU - Jeong CW AU - Lee SE FA - Oh, Jong Jin FA - Byun, Seoksoo FA - Hong, Sung Kyu FA - Jeong, Chang Wook FA - Lee, Sang Eun IN - Oh, Jong Jin. Department of Urology, Seoul National University Bundang Hospital, Seongnam, Korea. IN - Byun, Seoksoo. Department of Urology, Seoul National University Bundang Hospital, Seongnam, Korea. IN - Hong, Sung Kyu. Department of Urology, Seoul National University Bundang Hospital, Seongnam, Korea. IN - Jeong, Chang Wook. Department of Urology, Seoul National University Bundang Hospital, Seongnam, Korea. IN - Lee, Sang Eun. Department of Urology, Seoul National University Bundang Hospital, Seongnam, Korea. TI - Comparison of robotic and open partial nephrectomy: Single-surgeon matched cohort study. SO - Canadian Urological Association Journal. 8(7-8):E471-5, 2014 Jul AS - Can Urol Assoc J. 8(7-8):E471-5, 2014 Jul NJ - Canadian Urological Association journal = Journal de l'Association des urologues du Canada PI - Journal available in: Print PI - Citation processed from: Print JC - 101312644 IO - Can Urol Assoc J PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113577 CP - Canada AB - INTRODUCTION: We present comparative outcomes among matched patients who underwent robotic partial nephrectomy (RPN) or open partial nephrectomy (OPN) by a single surgeon at a single institution. AB - METHODS: We reviewed the medical records of 200 patients who underwent RPN (n = 100) or OPN (n = 100) between May 2003 and May 2013. The patients who underwent RPN were matched for age, gender, body mass index (BMI), American Society of Anesthesiologists (ASA) score, as well as tumour size, side and location. Perioperative outcomes were compared. AB - RESULTS: There was no significant difference between the 2 cohorts with respect to patient age, BMI, ASA score, preoperative glomerular filtration rate, tumour size and the R.E.N.A.L. nephrometry score. The mean operative time was longer in the RPN group, but there were no significant differences with respect to warm ischemic time and postoperative renal function. The length of hospitalization and use of postoperative analgesics (ketoprofen) were more favourable in the RPN cohort. There was no significant difference in the mean estimated blood loss, transfusion rate, or complications between the cohorts. AB - CONCLUSIONS: Considering the perioperative and postoperative parameters, RPN is a viable option as a nephron-sparing surgical procedure for small renal masses that yields outcomes comparable to those achieved with OPN. Despite matched cohort analysis among patients who underwent PN by a single surgeon, there may be inherent selection bias; therefore future prospective trials are needed. IS - 1911-6470 IL - 1911-6470 DI - cuaj-7-8-471 DO - https://dx.doi.org/10.5489/cuaj.1679 PT - Journal Article ID - 25132891 [pubmed] ID - 10.5489/cuaj.1679 [doi] ID - cuaj-7-8-471 [pii] ID - PMC4113577 [pmc] PP - ppublish LG - English DP - 2014 Jul DC - 20140818 EZ - 2014/08/19 06:00 DA - 2014/08/19 06:01 DT - 2014/08/19 06:00 YR - 2014 ED - 20140818 RD - 20170214 UP - 20170216 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=25132891 <247. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23594146 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - De Coninck V AU - Braeckman J AU - Michielsen D FA - De Coninck, Vincent FA - Braeckman, Johan FA - Michielsen, Dirk IN - De Coninck, Vincent. Department of Urology, UZ Brussel, Free University of Brussels, Brussels, Belgium. TI - Prostate HistoScanning: a screening tool for prostate cancer?. CM - Comment in: Int J Urol. 2013 Dec;20(12):1192; PMID: 23594191 CM - Comment in: Int J Urol. 2013 Dec;20(12):1191; PMID: 23594168 SO - International Journal of Urology. 20(12):1184-90, 2013 Dec AS - Int J Urol. 20(12):1184-90, 2013 Dec NJ - International journal of urology : official journal of the Japanese Urological Association PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - ce6, 9440237 IO - Int. J. Urol. SB - Index Medicus CP - Australia MH - Aged MH - Aged, 80 and over MH - *Biopsy/mt [Methods] MH - Digital Rectal Examination MH - Follow-Up Studies MH - Humans MH - Kallikreins/bl [Blood] MH - Logistic Models MH - Male MH - *Mass Screening/mt [Methods] MH - Middle Aged MH - Neoplasm Grading MH - Pilot Projects MH - Predictive Value of Tests MH - Prostate/dg [Diagnostic Imaging] MH - *Prostate/pa [Pathology] MH - Prostate-Specific Antigen/bl [Blood] MH - Prostatic Neoplasms/dg [Diagnostic Imaging] MH - *Prostatic Neoplasms/pa [Pathology] MH - Ultrasonography KW - HistoScanning; biopsy; prostate cancer AB - OBJECTIVE: To evaluate Prostate HistoScanning as a screening tool for prostate cancer in a pilot study. AB - METHODS: During a 6-month period, 94 men with normal or suspicious digital rectal examination, normal or elevated prostate-specific antigen, or an increased prostate-specific antigen velocity were examined with Prostate HistoScanning. Based on these parameters and HistoScanning analysis, 41 men were referred for prostate biopsy under computer-aided ultrasonographic guidance. The number of random biopsy cores varied depending on the prostate volume. Targeted biopsies were taken in the case of computer-aided ultrasonographic area suspicious for malignancy. A logistic regression analysis was carried out to estimate the probability of resulting in a positive prostate biopsy based on the HistoScanning findings. AB - RESULTS: Following a logistic regression analysis, after adjusting for age, digital rectal examination, serum prostate-specific antigen level, prostate volume and tumor lesion volume, every cancer volume increase of 1mL estimated by HistoScanning was associated with a nearly threefold increase in the probability of resulting in a positive biopsy (odds ratio 2.9; 95% confidence interval 1.2-7.0; P-value 0.02). Prostate cancer was found in 17 of 41 men (41%). In patients with cancer, computer-aided ultrasonography-guided biopsy was 4.5-fold more likely to detect cancer than random biopsy. The prostate cancer detection rate for random biopsy and directed biopsy was 13% and 58%, respectively. HistoScanning-guided biopsy significantly decreased the number of biopsies necessary (P-value <0.0001). AB - CONCLUSIONS: Our findings suggest that Prostate HistoScanning might be helpful for the selection of patients in whom prostate biopsies are necessary. This imaging technique can be used to direct biopsies in specific regions of the prostate with a higher cancer detection rate. AB - Copyright © 2013 The Japanese Urological Association. RN - EC 3-4-21 (Kallikreins) RN - EC 3-4-21 (kallikrein-related peptidase 3, human) RN - EC 3-4-21-77 (Prostate-Specific Antigen) ES - 1442-2042 IL - 0919-8172 DO - https://dx.doi.org/10.1111/iju.12148 PT - Clinical Trial PT - Journal Article ID - 23594146 [pubmed] ID - 10.1111/iju.12148 [doi] PP - ppublish PH - 2012/09/20 [received] PH - 2013/02/25 [accepted] LG - English EP - 20130417 DP - 2013 Dec DC - 20131202 EZ - 2013/04/19 06:00 DA - 2014/08/13 06:00 DT - 2013/04/19 06:00 YR - 2013 ED - 20140812 RD - 20161128 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23594146 <248. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23357349 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Geraerts I AU - Van Poppel H AU - Devoogdt N AU - Joniau S AU - Van Cleynenbreugel B AU - De Groef A AU - Van Kampen M FA - Geraerts, Inge FA - Van Poppel, Hendrik FA - Devoogdt, Nele FA - Joniau, Steven FA - Van Cleynenbreugel, Ben FA - De Groef, An FA - Van Kampen, Marijke IN - Geraerts, Inge. KU Leuven, Department of Rehabilitation Science, Leuven, Belgium. Electronic address: inge.geraerts@faber.kuleuven.be. TI - Influence of preoperative and postoperative pelvic floor muscle training (PFMT) compared with postoperative PFMT on urinary incontinence after radical prostatectomy: a randomized controlled trial. CM - Comment in: Eur Urol. 2013 Nov;64(5):773-5; discussion 775-6; PMID: 23499365 SO - European Urology. 64(5):766-72, 2013 Nov AS - Eur Urol. 64(5):766-72, 2013 Nov NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Adult MH - Aged MH - Belgium MH - *Exercise Therapy MH - Humans MH - Kaplan-Meier Estimate MH - Male MH - Middle Aged MH - *Pelvic Floor/pp [Physiopathology] MH - Proportional Hazards Models MH - Prospective Studies MH - *Prostatectomy/ae [Adverse Effects] MH - Quality of Life MH - Recovery of Function MH - Risk Factors MH - Time Factors MH - Treatment Outcome MH - Urinary Incontinence/di [Diagnosis] MH - Urinary Incontinence/et [Etiology] MH - Urinary Incontinence/pp [Physiopathology] MH - *Urinary Incontinence/pc [Prevention & Control] MH - Urodynamics KW - Pelvic floor muscle training; Radical prostatectomy; Urinary incontinence AB - BACKGROUND: The efficacy of preoperative pelvic floor muscle training (PFMT) for urinary incontinence (UI) after open radical prostatectomy (ORP) and robot-assisted laparoscopic radical prostatectomy (RARP) is still unclear. AB - OBJECTIVE: To determine whether patients with additional preoperative PFMT regain urinary continence earlier than patients with only postoperative PFMT after ORP and RARP. AB - DESIGN, SETTING, AND PARTICIPANTS: A randomized controlled trial enrolled 180 men who planned to undergo ORP/RARP. AB - INTERVENTION: The experimental group (E, n=91) started PFMT 3 wk before surgery and continued after surgery. The control group (C, n=89) started PFMT after catheter removal. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: The primary end point was time to continence. Patients measured urine loss daily (24-h pad test) until total continence (three consecutive days of 0 g of urine loss) was achieved. Secondary end points were 1-h pad test, visual analog scale (VAS), International Prostate Symptom Score (IPSS), and quality of life (King's Health Questionnaire [KHQ]). Kaplan-Meier analysis and Cox regression with correction for two strata (age and type of surgery) compared time and continence. The Fisher exact test was applied for the 1-h pad test and VAS; the Mann-Whitney U test was applied for IPSS and KHQ. AB - RESULTS AND LIMITATIONS: Patients with additional preoperative PFMT had no shorter duration of postoperative UI compared with patients with only postoperative PFMT (p=0.878). Median time to continence was 30 and 31 d, and median amount of first-day incontinence was 108 g and 124 g for groups E and C, respectively. Cox regression did not indicate a significant difference between groups E and C (p=0.773; hazard ratio: 1.047 [0.768-1.425]). The 1-h pad test, VAS, and IPSS were comparable between both groups. However, "incontinence impact" (KHQ) was in favor of group E at 3 mo and 6 mo after surgery. AB - CONCLUSIONS: Three preoperative sessions of PFMT did not improve postoperative duration of incontinence. AB - TRIAL REGISTRATION: Netherlands Trial Register No. NTR 1953. AB - Copyright © 2013 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(13)00025-0 DO - https://dx.doi.org/10.1016/j.eururo.2013.01.013 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 23357349 [pubmed] ID - S0302-2838(13)00025-0 [pii] ID - 10.1016/j.eururo.2013.01.013 [doi] PP - ppublish PH - 2012/11/14 [received] PH - 2013/01/14 [accepted] SI - NTR SA - NTR/NTR1953 LG - English EP - 20130121 DP - 2013 Nov DC - 20131011 EZ - 2013/01/30 06:00 DA - 2014/08/05 06:00 DT - 2013/01/30 06:00 YR - 2013 ED - 20140804 RD - 20131011 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23357349 <249. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23510321 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Pastore AL AU - Palleschi G AU - Silvestri L AU - Leto A AU - Sacchi K AU - Pacini L AU - Petrozza V AU - Carbone A FA - Pastore, Antonio Luigi FA - Palleschi, Giovanni FA - Silvestri, Luigi FA - Leto, Antonino FA - Sacchi, Kevin FA - Pacini, Luca FA - Petrozza, Vincenzo FA - Carbone, Antonio IN - Pastore, Antonio Luigi. Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Faculty of Pharmacy and Medicine, Urology Unit ICOT, Latina, Italy. antopast@hotmail.com TI - Prospective randomized study of radiofrequency versus ultrasound scalpels on functional outcomes of laparoscopic radical prostatectomy. SO - Journal of Endourology. 27(8):989-93, 2013 Aug AS - J Endourol. 27(8):989-93, 2013 Aug NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - *Catheter Ablation/is [Instrumentation] MH - Humans MH - *Laparoscopy/mt [Methods] MH - Length of Stay MH - Male MH - Middle Aged MH - Postoperative Complications/et [Etiology] MH - Postoperative Complications/pp [Physiopathology] MH - Prospective Studies MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - Surveys and Questionnaires MH - Treatment Outcome MH - *Ultrasonic Surgical Procedures/is [Instrumentation] MH - *Urinary Incontinence/et [Etiology] MH - Urinary Incontinence/pp [Physiopathology] MH - Urodynamics AB - BACKGROUND AND PURPOSE: Surgical treatment of patients with prostate cancer currently involves laparoscopic radical prostatectomy (LRP) or robot-assisted LRP. Continence and nerve-sparing procedures in these techniques are supported by dissection and hemostatic surgical devices powered by different types of energy. The aim of this study was to assess recovery of continence and erectile function after laparoscopic extraperitoneal radical prostatectomy comparing two surgical devices for dissection and hemostasis-radiofrequency (RF) and ultrasound (US) scalpels. AB - PATIENTS AND METHODS: A total of 132 men with localized prostate cancer were prospectively enrolled and scheduled for extraperitoneal LRP. Patients were randomly assigned to the RF group (LigaSure; n=66) or the US group (UltraCision; n=66). Outcomes were measured by the self-administered questionnaires (International Consultation on Incontinence Questionnaire-Urinary Incontinence [ICIQ-UI] and International Index of Erectile Function 5 [IIEF 5]) 15 days before surgery, 90 and 180 days after prostatectomy to assess recovery of urinary continence and erectile function. AB - RESULTS: No significant difference was found between the two groups regarding operative time, intra- and perioperative complications, or time of hospital stay. At 180 days after surgery, patients in the RF-treated group showed better recovery in terms of continence and erectile function compared with patients in the US group (ICIQ-UI: p=0.0016; IIEF 5: p=0.0352). AB - CONCLUSIONS: The use of the RF scalpel provided better functional outcomes compared with the US scalpel in patients undergoing extraperitoneal LRP. This might be attributed to the low contiguous damage of those tissues, which are not directly involved in dissection and hemostasis, achieved using the RF device. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2013.0033 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 23510321 [pubmed] ID - 10.1089/end.2013.0033 [doi] PP - ppublish LG - English EP - 20130523 DP - 2013 Aug DC - 20130820 EZ - 2013/03/21 06:00 DA - 2014/07/23 06:00 DT - 2013/03/21 06:00 YR - 2013 ED - 20140722 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23510321 <250. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24472002 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Danuser H AU - Germann C AU - Pelzer N AU - Ruhle A AU - Stucki P AU - Mattei A FA - Danuser, H FA - Germann, C FA - Pelzer, N FA - Ruhle, A FA - Stucki, P FA - Mattei, A IN - Danuser, H. Klinik fur Urologie, Luzerner Kantonsspital, Lucerne, Switzerland. TI - One- vs 4-week stent placement after laparoscopic and robot-assisted pyeloplasty: results of a prospective randomised single-centre study. CM - Comment in: BJU Int. 2014 Jun;113(6):846-7; PMID: 24905657 CM - Comment in: J Urol. 2015 Jan;193(1):171-2; PMID: 25523669 SO - BJU International. 113(6):931-5, 2014 Jun AS - BJU Int. 113(6):931-5, 2014 Jun NJ - BJU international PI - Journal available in: Print PI - Citation processed from: Internet JC - dcu, 100886721 IO - BJU Int. SB - Index Medicus CP - England MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Female MH - Humans MH - *Kidney Pelvis/su [Surgery] MH - *Laparoscopy MH - Male MH - Middle Aged MH - Prospective Studies MH - *Robotics MH - *Stents MH - Time Factors MH - *Ureteral Obstruction/su [Surgery] MH - Urologic Surgical Procedures/mt [Methods] MH - Young Adult KW - laparoscopic; pelvi-ureteric junction obstruction; pyeloplasty; robot-assisted; stenting AB - OBJECTIVES: To determine whether 1-week stenting of the pelvi-ureteric anastomosis of laparoscopic or robot-assisted pyeloplasty is as effective as 4-week stenting, based on their respective success rates. AB - PATIENTS AND METHODS: A total of 100 patients with pelvi-ureteric junction obstruction were treated by Anderson-Hynes pyeloplasty and the anastomosis was stented using a 6-F JJ catheter for either 1 week (1W series) or 4 weeks (4W series), based on a randomisation protocol. Postoperative follow-up was performed at 3 months using intravenous urography (IVU), at 6 months using diuretic renography and at 1, 3 and 5 years using ultrasonography. Statistical analysis was performed using a one-sided Z-test, Pearsons's chi-squared test and a Wilcoxon rank sum test. AB - RESULTS: The primary outcome measure, success rate, which was defined as no obstruction on IVU and diuretic renography, was 100% in the 1W series and not inferior to the success rate of 98% in the 4W series (P = 0.006). The following secondary outcome measures were not significantly different between the 1W and the 4W series with regard to residual symptoms (10 vs 6%; P = 0.48), rate of complications (4 vs 6%; P = 0.65), need for synchronous robot-assisted pyelolithotomy (4 vs 8%; P = 0.47), improvement in split renal function (1 vs 0%; P = 0.59) and duration of surgery (200 vs 192min; P = 0.87). Only length of hospital stay was significantly different; this was shorter in the 1W series (5 vs 6 days; P = 0.01). AB - CONCLUSIONS: Stenting of the pelvi-ureteric anastomosis after laparoscopic or robot-assisted pyeloplasty for 1 week is as effective as stenting for 4 weeks. Both procedures, laparoscopic or robot-assisted pyeloplasty have an excellent success rate. AB - Copyright © 2014 The Authors. BJU International © 2014 BJU International. ES - 1464-410X IL - 1464-4096 DO - https://dx.doi.org/10.1111/bju.12652 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 24472002 [pubmed] ID - 10.1111/bju.12652 [doi] PP - ppublish LG - English DP - 2014 Jun DC - 20140609 EZ - 2014/01/30 06:00 DA - 2014/07/22 06:00 DT - 2014/01/30 06:00 YR - 2014 ED - 20140721 RD - 20150206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24472002 <251. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24848908 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Nieboer TE AU - Aarts JW FA - Nieboer, Theodoor E FA - Aarts, Johanna W M IN - Nieboer, Theodoor E. Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands Department of Obstetrics and Gynecology, Gelderse Vallei Hospital, Ede, The Netherlands. TI - Robotic compared with laparoscopic sacrocolpopexy: a randomized controlled trial. CM - Comment on: Obstet Gynecol. 2014 Jan;123(1):1-2; PMID: 24463655 CM - Comment on: Obstet Gynecol. 2014 Jan;123(1):3-4; PMID: 24463656 CM - Comment on: Obstet Gynecol. 2014 Jan;123(1):5-12; PMID: 24463657 CM - Comment on: Obstet Gynecol. 2014 Jan;123(1):13-20; PMID: 24463658 SO - Obstetrics & Gynecology. 123(6):1357-8, 2014 Jun AS - Obstet Gynecol. 123(6):1357-8, 2014 Jun NJ - Obstetrics and gynecology PI - Journal available in: Print PI - Citation processed from: Internet JC - oc2, 0401101 IO - Obstet Gynecol SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Female MH - *Gynecologic Surgical Procedures/td [Trends] MH - Humans MH - *Laparoscopy/td [Trends] MH - *Pelvic Organ Prolapse/su [Surgery] MH - *Robotics/td [Trends] ES - 1873-233X IL - 0029-7844 DI - 00006250-201406000-00038 DO - https://dx.doi.org/10.1097/AOG.0000000000000311 PT - Comment PT - Letter ID - 24848908 [pubmed] ID - 10.1097/AOG.0000000000000311 [doi] ID - 00006250-201406000-00038 [pii] PP - ppublish LG - English DP - 2014 Jun DC - 20140522 EZ - 2014/05/23 06:00 DA - 2014/07/16 06:00 DT - 2014/05/23 06:00 YR - 2014 ED - 20140714 RD - 20140522 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24848908 <252. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24177256 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Rossi EC AU - Jackson A AU - Ivanova A AU - Boggess JF FA - Rossi, Emma C FA - Jackson, Amanda FA - Ivanova, Anastasia FA - Boggess, John F IN - Rossi, Emma C. *Division of Gynecologic Oncology, Indiana University Health Melvin and Bren Simon Cancer Center, Indianapolis, IN; +Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC; and ++Department of Biostatistics, University of North Carolina, Chapel Hill, NC. TI - Detection of sentinel nodes for endometrial cancer with robotic assisted fluorescence imaging: cervical versus hysteroscopic injection. SO - International Journal of Gynecological Cancer. 23(9):1704-11, 2013 Nov AS - Int J Gynecol Cancer. 23(9):1704-11, 2013 Nov NJ - International journal of gynecological cancer : official journal of the International Gynecological Cancer Society PI - Journal available in: Print PI - Citation processed from: Internet JC - dzp, 9111626 IO - Int. J. Gynecol. Cancer SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Cervix Uteri MH - *Endometrial Neoplasms/di [Diagnosis] MH - *Endometrial Neoplasms/pa [Pathology] MH - Feasibility Studies MH - Female MH - Humans MH - Hysteroscopy MH - *Indocyanine Green/ad [Administration & Dosage] MH - Indocyanine Green/pk [Pharmacokinetics] MH - Injections MH - *Lymph Nodes/pa [Pathology] MH - Middle Aged MH - Optical Imaging/is [Instrumentation] MH - *Optical Imaging/mt [Methods] MH - Robotics MH - Spectroscopy, Near-Infrared MH - Young Adult AB - OBJECTIVE: Sentinel lymph node (SLN) mapping with indocyanine green (ICG) detected by robotic near infrared (NIR) imaging is a feasible technique. The optimal site of injection (cervical or endometrial) for endometrial cancer has yet to be determined. We prospectively evaluated SLN mapping after cervical and endometrial injections of ICG to compare the detection rates and patterns of nodal distribution. AB - METHODS: Twenty-nine subjects with endometrial cancer undergoing robotic hysterectomy with lymphadenectomy by a single surgeon received SLN mapping with robotic fluorescence imaging. Seventeen patients received cervical injections of 1 mg of ICG and 12 patients received hysteroscopic endometrial injections of 0.5-mg ICG. Detection rates between the 2 groups were compared using Fisher exact tests. Continuous variables such as operating room times and body mass index were compared using t tests. AB - RESULTS: The SLN detection rate was 82% (14/17) for cervical and 33% (4/12) for hysteroscopic injection (P = 0.027). Sentinel lymph nodes were seen bilaterally in 57% (8/14) of the cervical injection group and 50% (2/4) of the hysteroscopic group. Para-aortic SLNs were seen in 71% (10/14) of patients who mapped after cervical injection and 75% (3/4) patients who mapped after hysteroscopic injection. There was 1 false-negative SLN in the cervical injection group. AB - CONCLUSIONS: Cervical ICG injection achieves a higher SLN detection rate and a similar anatomic nodal distribution as hysteroscopic endometrial injection for SLN mapping in patients with endometrial cancer. RN - IX6J1063HV (Indocyanine Green) ES - 1525-1438 IL - 1048-891X DI - 00009577-201311000-00025 DO - https://dx.doi.org/10.1097/IGC.0b013e3182a616f6 PT - Clinical Trial PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't ID - 24177256 [pubmed] ID - 10.1097/IGC.0b013e3182a616f6 [doi] ID - 00009577-201311000-00025 [pii] PP - ppublish LG - English DP - 2013 Nov DC - 20131101 EZ - 2013/11/02 06:00 DA - 2014/07/02 06:00 DT - 2013/11/02 06:00 YR - 2013 ED - 20140701 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24177256 <253. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24053198 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Carter SC AU - Lipsitz S AU - Shih YC AU - Nguyen PL AU - Trinh QD AU - Hu JC FA - Carter, Stacey C FA - Lipsitz, Stuart FA - Shih, Ya-Chen T FA - Nguyen, Paul L FA - Trinh, Quoc-Dien FA - Hu, Jim C IN - Carter, Stacey C. Department of Urology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. TI - Population-based determinants of radical prostatectomy operative time. SO - BJU International. 113(5b):E112-8, 2014 May AS - BJU Int. 113(5b):E112-8, 2014 May NJ - BJU international PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - dcu, 100886721 IO - BJU Int. SB - Index Medicus CP - England MH - Aged MH - Cohort Studies MH - Humans MH - Male MH - *Operative Time MH - *Prostatectomy/st [Standards] KW - operative time; prostate cancer; prostatectomy; retropubic radical prostatectomy; robot-assisted radical prostatectomy AB - OBJECTIVES: To determine factors that influence radical prostatectomy (RP) operative times. Operative time assessment is inherent to defining surgeon learning curves and evaluating quality of care. AB - SUBJECTS/PATIENTS AND METHODS: Population-based observational cohort study using USA Surveillance, Epidemiology, and End Results (SEER)-Medicare linked data of men diagnosed with prostate cancer during 2003-2007 who underwent robot-assisted radical prostatectomy (RARP, 3458 men) and retropubic RP (RRP, 6993) through to 2009. We obtained median operative time using anaesthesia administrative data for RP and used median regression to assess the contribution of patient, surgeon, and hospital factors to operative times. AB - RESULTS: The median RARP operative time decreased from 315 to 247min from 2003 to 2008-2009 (P < 0.001), while the median RRP operative time remained similar (195 vs 197min, P = 0.90). In adjusted analysis, RARP vs RRP (parameter estimate [PE] 70.9; 95% confidence interval [CI] 58, 84; P < 0.001) and obesity (PE 15; 95% CI 7, 23; P < 0.001) were associated with longer operative times while higher surgeon volumes were associated with shorter operative times (P < 0.001). RPs performed by surgeons employed by group (parameter estimate [PE] -22.76; 95% CI -38, -7.49; P = 0.004) and non-government (PE -35.59; 95% CI -68.15, -3.03; P = 0.032) vs government facilities and non-profit vs government hospital ownership (PE -21.85; 95% CI -32.28, -11.42; P < 0.001) were associated with shorter operative times. AB - CONCLUSIONS: During our study period, RARP operative times decreased by 68min while RRP operative times remained stagnant. Higher surgeon volume was associated with shorter operative times, and selective referral or improved efficiency to the level of high-volume surgeons would net almost $15 million (USA dollars) in annual savings. AB - Copyright © 2013 The Authors. BJU International © 2013 BJU International. ES - 1464-410X IL - 1464-4096 DO - https://dx.doi.org/10.1111/bju.12451 PT - Journal Article PT - Observational Study PT - Research Support, N.I.H., Extramural PT - Research Support, U.S. Gov't, P.H.S. ID - 24053198 [pubmed] ID - 10.1111/bju.12451 [doi] PP - ppublish GI - No: R01 CA160679 Organization: (CA) *NCI NIH HHS* Country: United States No: R01 HS020263 Organization: (HS) *AHRQ HHS* Country: United States No: R01HS018535 Organization: (HS) *AHRQ HHS* Country: United States No: R21 CA165092 Organization: (CA) *NCI NIH HHS* Country: United States LG - English EP - 20140115 DP - 2014 May DC - 20140423 EZ - 2013/09/24 06:00 DA - 2014/06/17 06:00 DT - 2013/09/24 06:00 YR - 2014 ED - 20140616 RD - 20161019 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24053198 <254. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24589412 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Vizza E AU - Corrado G AU - Zanagnolo V AU - Tomaselli T AU - Cutillo G AU - Mancini E AU - Maggioni A FA - Vizza, Enrico FA - Corrado, Giacomo FA - Zanagnolo, Vanna FA - Tomaselli, Tiziana FA - Cutillo, Giuseppe FA - Mancini, Emanuela FA - Maggioni, Angelo IN - Vizza, Enrico. Department of Oncological Surgery, Gynecologic Oncologic Unit, "Regina Elena" National Cancer Institute, Rome, Italy. IN - Corrado, Giacomo. Department of Oncological Surgery, Gynecologic Oncologic Unit, "Regina Elena" National Cancer Institute, Rome, Italy. Electronic address: giacomo.corrado@alice.it. IN - Zanagnolo, Vanna. Department of Gynecology, Cervical Cancer Center, European Institute of Oncology, Milan, Italy. IN - Tomaselli, Tiziana. Department of Gynecology, Cervical Cancer Center, European Institute of Oncology, Milan, Italy. IN - Cutillo, Giuseppe. Department of Oncological Surgery, Gynecologic Oncologic Unit, "Regina Elena" National Cancer Institute, Rome, Italy. IN - Mancini, Emanuela. Department of Oncological Surgery, Gynecologic Oncologic Unit, "Regina Elena" National Cancer Institute, Rome, Italy. IN - Maggioni, Angelo. Department of Gynecology, Cervical Cancer Center, European Institute of Oncology, Milan, Italy. TI - Neoadjuvant chemotherapy followed by robotic radical hysterectomy in locally advanced cervical cancer: a multi-institution study. SO - Gynecologic Oncology. 133(2):180-5, 2014 May AS - Gynecol Oncol. 133(2):180-5, 2014 May NJ - Gynecologic oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - fxc, 0365304 IO - Gynecol. Oncol. SB - Index Medicus CP - United States MH - Adenocarcinoma/pa [Pathology] MH - *Adenocarcinoma/th [Therapy] MH - Adult MH - Aged MH - *Antineoplastic Combined Chemotherapy Protocols/tu [Therapeutic Use] MH - Carcinoma, Squamous Cell/pa [Pathology] MH - *Carcinoma, Squamous Cell/th [Therapy] MH - Chemotherapy, Adjuvant/mt [Methods] MH - Cisplatin/ad [Administration & Dosage] MH - Combined Modality Therapy/mt [Methods] MH - Epirubicin/ad [Administration & Dosage] MH - Feasibility Studies MH - Female MH - Humans MH - *Hysterectomy/mt [Methods] MH - Ifosfamide/ad [Administration & Dosage] MH - *Lymph Node Excision MH - Middle Aged MH - Neoadjuvant Therapy/mt [Methods] MH - Paclitaxel/ad [Administration & Dosage] MH - Pelvis MH - Retrospective Studies MH - *Robotics/mt [Methods] MH - Treatment Outcome MH - Uterine Cervical Neoplasms/pa [Pathology] MH - *Uterine Cervical Neoplasms/th [Therapy] MH - Young Adult KW - Locally advanced cervical cancer; Minimally invasive surgery; Neo-adjuvant chemotherapy; Robotic radical hysterectomy AB - OBJECTIVE: Minimally invasive surgery has been performed in locally advanced cervical cancer (LACC) without adverse effect in patient's overall prognosis and survival. The aim of this report is to evaluate the feasibility and morbidity of total robotic radical hysterectomy (TRRH) with pelvic lymphadenectomy in patients with LACC after neo-adjuvant chemotherapy (NACT). AB - METHODS: From February 2008 to April 2013 a retrospective data collection of women undergoing TRRH for cervical cancer stage FIGO IB2 to IIB, after neo-adjuvant chemotherapy, was conducted at "Regina Elena" National Cancer Institute of Rome and European Institute of Oncology of Milan. All patients deemed operable underwent TRRH with pelvic lymphadenectomy within 4 weeks from the last chemotherapy cycle. AB - RESULTS: Median operative time was 225 min (range, 105-387 min). The median blood loss was 150 mL (range, 30-700 mL). The median number of removed pelvic lymph nodes was 23 (range, 8-69). Sixteen patients had an optimal response (12 PCR, 4 pPR1) to chemotherapy, 33 patients had a pPR2 and 11 patient showed stable disease. Adjuvant therapy was administrated in 36 patients (60%). We experienced one intra-operative complication and 19 post-operative complications, but no conversions to laparotomy were necessary to manage these complications. Six patients received a blood transfusion. At the time of this report, with a median follow-up of 28.9 months, 50 patients (83%) are free from recurrence. AB - CONCLUSION: This experience demonstrates the feasibility of TRRH pelvic lymphadenectomy after NACT in LACC with good accuracy and safety. AB - Copyright © 2014 Elsevier Inc. All rights reserved. RN - 3Z8479ZZ5X (Epirubicin) RN - P88XT4IS4D (Paclitaxel) RN - Q20Q21Q62J (Cisplatin) RN - UM20QQM95Y (Ifosfamide) ES - 1095-6859 IL - 0090-8258 DI - S0090-8258(14)00180-2 DO - https://dx.doi.org/10.1016/j.ygyno.2014.02.035 PT - Journal Article PT - Multicenter Study PT - Observational Study ID - 24589412 [pubmed] ID - S0090-8258(14)00180-2 [pii] ID - 10.1016/j.ygyno.2014.02.035 [doi] PP - ppublish PH - 2013/10/17 [received] PH - 2014/02/18 [revised] PH - 2014/02/23 [accepted] LG - English EP - 20140301 DP - 2014 May DC - 20140429 EZ - 2014/03/05 06:00 DA - 2014/06/13 06:00 DT - 2014/03/05 06:00 YR - 2014 ED - 20140612 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24589412 <255. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23750778 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Wong KC AU - Jones M AU - Webb T AU - Qureshi N AU - Bashir Y AU - Betts TR AU - Rajappan K FA - Wong, Kelvin C K FA - Jones, Michael FA - Webb, Terence FA - Qureshi, Norman FA - Bashir, Yaver FA - Betts, Timothy R FA - Rajappan, Kim IN - Wong, Kelvin C K. Oxford Heart Centre, Oxford University Hospitals NHS Trust, Oxford, UK. TI - Mitral isthmus ablation is feasible, efficacious, and safe using a remote robotic catheter system. CM - Comment in: Pacing Clin Electrophysiol. 2014 Jan;37(1):128-9; PMID: 23992450 CM - Comment in: Pacing Clin Electrophysiol. 2014 Jan;37(1):128; PMID: 23992482 SO - Pacing & Clinical Electrophysiology. 36(11):1364-72, 2013 Nov AS - Pacing Clin Electrophysiol. 36(11):1364-72, 2013 Nov NJ - Pacing and clinical electrophysiology : PACE PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - pab, 7803944 IO - Pacing Clin Electrophysiol SB - Index Medicus CP - United States MH - Atrial Fibrillation/di [Diagnosis] MH - *Atrial Fibrillation/su [Surgery] MH - Catheter Ablation/ae [Adverse Effects] MH - *Catheter Ablation/is [Instrumentation] MH - Catheter Ablation/mt [Methods] MH - Equipment Design MH - Equipment Failure Analysis MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Mitral Valve/su [Surgery] MH - Postoperative Complications/et [Etiology] MH - Postoperative Complications/pc [Prevention & Control] MH - *Robotics/is [Instrumentation] MH - Robotics/mt [Methods] MH - *Surgery, Computer-Assisted/is [Instrumentation] MH - Surgery, Computer-Assisted/mt [Methods] MH - *Telemedicine/is [Instrumentation] MH - Telemedicine/mt [Methods] MH - Treatment Outcome KW - atrial fibrillation; mitral isthmus; radiofrequency ablation; robotic catheter system AB - BACKGROUND: There are limited data on the use of a remote robotic catheter system (RCS) for mitral isthmus (MI) ablation. AB - METHODS: This single-center, prospective, matched control study included 45 patients who underwent atrial fibrillation ablation using a remote RCS compared to 45 patients who underwent conventional ablation. All patients had circumferential pulmonary vein isolation (PVI), roof, and MI ablation. AB - RESULTS: There were no significant differences in baseline clinical characteristics. There were no significant differences in MI block (RCS: 44/45 [98%] vs AB - CONTROL: 43/45 [96%], P = 1.0), roof block (RCS: 45/45 [100%] vs AB - CONTROL: 44/45 [98%], P = 1.0), and PVI (RCS: 45/45 [100%] vs AB - CONTROL: 45/45 [100%], P = 1.0). Ablation and procedural times were similar in both arms. Using RCS, mean total MI ablation and procedure times were 13 +/- 6 minutes and 23 +/- 15 minutes, respectively. Coronary sinus (CS) ablation was significantly less in the RCS arm (48% vs 72%, P = 0.03). It was possible to "drive" the ablation catheter into the distal CS using the RCS in 19/22 (86%) patients. There was a significant trend of reduction in mean MI ablation (P = 0.008) and procedural times (P = 0.004) over the course of the study period. There was a significant reduction in fluoroscopy time in the RNS arm (33 +/- 17 minutes vs 49 +/- 20 minutes, P = 0.0004). AB - CONCLUSION: It is feasible and safe to use a remote RCS for MI ablation, including "driving into the CS." MI block was achieved in 98% with a significant reduction in the need for CS ablation (48%). There is a short learning curve. AB - Copyright ©2013, The Authors. Journal compilation ©2013 Wiley Periodicals, Inc. ES - 1540-8159 IL - 0147-8389 DO - https://dx.doi.org/10.1111/pace.12201 PT - Controlled Clinical Trial PT - Journal Article PT - Observational Study ID - 23750778 [pubmed] ID - 10.1111/pace.12201 [doi] PP - ppublish PH - 2012/09/28 [received] PH - 2013/04/21 [revised] PH - 2013/04/23 [accepted] LG - English EP - 20130610 DP - 2013 Nov DC - 20131029 EZ - 2013/06/12 06:00 DA - 2014/06/10 06:00 DT - 2013/06/12 06:00 YR - 2013 ED - 20140609 RD - 20140731 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23750778 <256. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24059674 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lusch A AU - Bucur PL AU - Menhadji AD AU - Okhunov Z AU - Liss MA AU - Perez-Lanzac A AU - McDougall EM AU - Landman J FA - Lusch, Achim FA - Bucur, Philip L FA - Menhadji, Ashleigh D FA - Okhunov, Zhamshid FA - Liss, Michael Andre FA - Perez-Lanzac, Alberto FA - McDougall, Elspeth M FA - Landman, Jaime IN - Lusch, Achim. Department of Urology, University of California , Irvine, Orange, California. TI - Evaluation of the impact of three-dimensional vision on laparoscopic performance. SO - Journal of Endourology. 28(2):261-6, 2014 Feb AS - J Endourol. 28(2):261-6, 2014 Feb NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - *Clinical Competence MH - Cross-Over Studies MH - Depth Perception MH - Education, Medical, Graduate MH - General Surgery/ed [Education] MH - Humans MH - Imaging, Three-Dimensional/is [Instrumentation] MH - *Imaging, Three-Dimensional/mt [Methods] MH - Internship and Residency MH - *Laparoscopy/st [Standards] MH - Pilot Projects MH - Prospective Studies MH - *Robotics MH - *Task Performance and Analysis MH - Vision, Ocular AB - INTRODUCTION: Recent technological advancements have led to the introduction of new three-dimensional (3D) cameras in laparoscopic surgery. The 3D view has been touted as useful during robotic surgery, however, there has been limited investigation into the utility of 3D in laparoscopy. AB - MATERIALS AND METHODS: We performed a prospective, randomized crossover trial comparing a 0degree 3D camera with a conventional 0degree two-dimensional (2D) camera using a high definition monitor (Karl Storz, Tuttlingen, Germany). All participants completed six standardized basic skills tasks. Quality testing scores were measured by the number of drops, grasping attempts, and precision of needle entry and exiting. Additionally, resolution, color distribution, depth of field and distortion were measured using optical test targets. AB - RESULTS: In this pilot study, we evaluated 10 medical students, 7 residents, and 7 expert surgeons. There was a significant difference in the performance in all the six skill tasks, for the three levels of surgical expertise and training levels in 2D vs 3D except for the cut the line quality score and the peg transfer quality score. Adjusting for the training level, 3D camera image results were superior for the number of rings left (p=0.041), ring transfer quality score (p=0.046), thread the rings (no. of rings) (p=0.0004), and thread the rings quality score (p=0.0002). The 3D camera image was also superior for knot tying (quality score) (p=0.004), peg transfer (time in seconds) (p=0.047), peg transfer pegs left (p=0.012), and for peg transfer quality score (p=0.001). The 3D camera system showed significantly less distortion (p=0.0008), a higher depth of field (p=0.0004) compared with the 2D camera system. AB - CONCLUSION: 3D laparoscopic camera equipment results in a significant improvement in depth perception, spatial location, and precision of surgical performance compared with the conventional 2D camera equipment. With this improved quality of vision, even expert laparoscopic surgeons may benefit from 3D imaging. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2013.0344 PT - Journal Article PT - Randomized Controlled Trial ID - 24059674 [pubmed] ID - 10.1089/end.2013.0344 [doi] PP - ppublish LG - English EP - 20140110 DP - 2014 Feb DC - 20140130 EZ - 2013/09/25 06:00 DA - 2014/05/10 06:00 DT - 2013/09/26 06:00 YR - 2014 ED - 20140509 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24059674 <257. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23987521 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Woo SH AU - Kang DI AU - Ha YS AU - Salmasi AH AU - Kim JH AU - Lee DH AU - Kim WJ AU - Kim IY FA - Woo, Seung Hyo FA - Kang, Dong Il FA - Ha, Yun-Sok FA - Salmasi, Amirali Hassanzadeh FA - Kim, Jeong Hyun FA - Lee, Dong-Hyeon FA - Kim, Wun-Jae FA - Kim, Isaac Yi IN - Woo, Seung Hyo. 1 Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey , New Brunswick, New Jersey. TI - Comprehensive analysis of sexual function outcome in prostate cancer patients after robot-assisted radical prostatectomy. SO - Journal of Endourology. 28(2):172-7, 2014 Feb AS - J Endourol. 28(2):172-7, 2014 Feb NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - *Erectile Dysfunction/di [Diagnosis] MH - Erectile Dysfunction/et [Etiology] MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Neoplasm Grading MH - Neoplasm Staging MH - *Postoperative Complications MH - Prognosis MH - Prospective Studies MH - *Prostatectomy/ae [Adverse Effects] MH - Prostatic Neoplasms/co [Complications] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Retrospective Studies MH - *Robotics MH - Survival Rate AB - PURPOSE: The recovery of potency following radical prostatectomy is complex and has a very wide range. In this study, we analyzed in detail the precise pattern of recovery of potency following robot-assisted radical prostatectomy (RARP). AB - MATERIALS AND METHODS: Prospectively collected database of patients with a minimum follow-up of 1 year after RARP were evaluated retrospectively. Of 503 patients identified, 483 patients completed the sexual health inventory for men (SHIM) preoperatively and postoperatively every 3 months for the first 12 months. Overall potency, usage of phosphodiesterase type-5 (PDE-5) inhibitors, and return to baseline erectile function were evaluated. Potency was defined as having erection that is sufficient for sexual intercourse more than 50% of attempts, while quality potency was defined as being potent without the use of PDE-5 inhibitors. AB - RESULTS: Preoperatively, the overall potency and quality potency rate were 67.1% and 48.1%, respectively. Postoperatively, the overall potency rate was 61.4%, while the quality potency rate was 37.2%. In multivariate regression analysis, independent predictors of potency recovery were young age (<60), preoperative potency status, and bilateral preservation of neurovascular bundles (NVBs). In men with SHIM>21, the overall potency and quality potency rate were 79.7% and 41.2%, respectively. More importantly, only 21.4% of the men with normal erection preoperatively (SHIM>21) returned to baseline erectile function (SHIM>21) 12 months after surgery. AB - CONCLUSIONS: This study indicates that young age (<60), preoperative potency, and bilateral preservation of NVBs were positive predictors of potency recovery following RARP. However, an overwhelming majority of men experience a deterioration in the overall quality of erection after RARP. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2013.0304 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 23987521 [pubmed] ID - 10.1089/end.2013.0304 [doi] PP - ppublish LG - English EP - 20131023 DP - 2014 Feb DC - 20140130 EZ - 2013/08/31 06:00 DA - 2014/05/10 06:00 DT - 2013/08/31 06:00 YR - 2014 ED - 20140509 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23987521 <258. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24581526 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Dal Moro F AU - Crestani A AU - Valotto C AU - Zattoni F FA - Dal Moro, Fabrizio FA - Crestani, Alessandro FA - Valotto, Claudio FA - Zattoni, Filiberto IN - Dal Moro, Fabrizio. Department of Surgical, Oncological and Gastroenterological Sciences-Urology, University of Padova, Padova, Italy. Electronic address: fabrizio.dalmoro@unipd.it. IN - Crestani, Alessandro. Department of Surgical, Oncological and Gastroenterological Sciences-Urology, University of Padova, Padova, Italy. IN - Valotto, Claudio. Department of Surgical, Oncological and Gastroenterological Sciences-Urology, University of Padova, Padova, Italy. IN - Zattoni, Filiberto. Department of Surgical, Oncological and Gastroenterological Sciences-Urology, University of Padova, Padova, Italy. TI - CORPUS--novel COmplete Reconstruction of the Posterior Urethral Support after robotic radical prostatectomy: preliminary data of very early continence recovery. SO - Urology. 83(3):641-7, 2014 Mar AS - Urology. 83(3):641-7, 2014 Mar NJ - Urology PI - Journal available in: Print PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Aged MH - Humans MH - Male MH - Middle Aged MH - Muscle, Skeletal/su [Surgery] MH - Prostate/pa [Pathology] MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Robotics MH - *Suburethral Slings MH - Surveys and Questionnaires MH - Suture Techniques MH - Urinary Incontinence/et [Etiology] MH - *Urinary Incontinence/pc [Prevention & Control] MH - Urination AB - INTRODUCTION: To determine whether a novel intraoperative technique of COmplete Reconstruction of the Posterior Urethral Support (CORPUS) improves early urinary continence after robotic-assisted radical prostatectomy (RARP). In this prospective study, between November 2012 and June 2013, 36 consecutive patients suitable for non-nerve-sparing RARP were alternatively assigned to either CORPUS surgery or Rocco's standard reconstruction. AB - TECHNICAL CONSIDERATIONS: In the CORPUS group, fibers of the bilateral portions of the puborectalis muscle were used to create a sort of posterior hammock for the urethra. The International Consultation on Incontinence Questionnaire, Short Form Questionnaire (ICIQ-SF) and International Prostate Symptom Score were collected for all patients preoperatively and then ICIQ-SF at 1 day and both tests at 30 days after catheter removal after RARP. Intraoperative and/or postoperative complications were evaluated. Pearson chi-square test compared urinary continence according to ICIQ-SF at 1 and 30 days. Statistical significance was set at P <.05. AB - CONCLUSION: Fifty percent of CORPUS patients were continent immediately after catheter removal and 83% after 30 days. In controls, the respective percentages were 16% and 61%. The differences were statistically significant in both cases. The International Prostate Symptom Score at 30 days did not show obstructive symptoms in either group. One limitation of this study is the low number of cases, "superselected" to evaluate the true effect of CORPUS reconstruction. The very early continence rate of the CORPUS patients was significantly improved compared with that of patients undergoing Rocco's standard technique. Further studies extending the inclusion criteria are needed to confirm the impact of the new CORPUS technique in a more heterogeneous group. AB - Copyright © 2014 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(13)01557-4 DO - https://dx.doi.org/10.1016/j.urology.2013.12.010 PT - Controlled Clinical Trial PT - Journal Article ID - 24581526 [pubmed] ID - S0090-4295(13)01557-4 [pii] ID - 10.1016/j.urology.2013.12.010 [doi] PP - ppublish PH - 2013/08/22 [received] PH - 2013/11/26 [revised] PH - 2013/12/03 [accepted] LG - English DP - 2014 Mar DC - 20140303 EZ - 2014/03/04 06:00 DA - 2014/04/30 06:00 DT - 2014/03/04 06:00 YR - 2014 ED - 20140429 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24581526 <259. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24387929 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kojima Y AU - Hamakawa T AU - Kubota Y AU - Ogawa S AU - Haga N AU - Tozawa K AU - Sasaki S AU - Hayashi Y AU - Kohri K FA - Kojima, Yoshiyuki FA - Hamakawa, Takashi FA - Kubota, Yasue FA - Ogawa, Soichiro FA - Haga, Nobuhiro FA - Tozawa, Keiichi FA - Sasaki, Shoichi FA - Hayashi, Yutaro FA - Kohri, Kenjiro IN - Kojima, Yoshiyuki. Department of Urology, Fukushima Medical University School of Medicine, Fukushima, Japan; Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. Electronic address: ykojima@fmu.ac.jp. IN - Hamakawa, Takashi. Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. IN - Kubota, Yasue. Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. IN - Ogawa, Soichiro. Department of Urology, Fukushima Medical University School of Medicine, Fukushima, Japan; Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. IN - Haga, Nobuhiro. Department of Urology, Fukushima Medical University School of Medicine, Fukushima, Japan. IN - Tozawa, Keiichi. Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. IN - Sasaki, Shoichi. Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. IN - Hayashi, Yutaro. Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. IN - Kohri, Kenjiro. Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. TI - Bladder neck sling suspension during robot-assisted radical prostatectomy to improve early return of urinary continence: a comparative analysis. CM - Comment in: Urology. 2014 Mar;83(3):639; discussion 639-40; PMID: 24387930 SO - Urology. 83(3):632-9, 2014 Mar AS - Urology. 83(3):632-9, 2014 Mar NJ - Urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Humans MH - Male MH - Middle Aged MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Prostatism/pp [Physiopathology] MH - Radiography MH - Recovery of Function MH - Robotics MH - *Suburethral Slings MH - Surveys and Questionnaires MH - Time Factors MH - Urinary Bladder/dg [Diagnostic Imaging] MH - *Urinary Bladder/su [Surgery] MH - Urinary Incontinence/et [Etiology] MH - *Urinary Incontinence/pc [Prevention & Control] MH - Urodynamics AB - OBJECTIVE: To present our experience of a novel technique, bladder neck sling suspension technique, in patients undergoing robot-assisted radical prostatectomy (RARP) and evaluate its efficacy for improving early continence outcomes after RARP in comparison with that of the standard technique. AB - METHODS: Fifty-seven consecutive patients underwent RARP between August 2011 and April 2012. We performed RARP with and without bladder neck sling suspension technique for 27 (sling group) and 30 (nonsling group) patients, respectively, and compared the urinary outcome between the groups. Both subjective and objective assessments of urinary incontinence were performed before and after RARP. AB - RESULTS: The International Prostate Symptom Score (P <.05) and International Consultation on Incontinence Questionnaire-Short Form (P <.05) in the sling group were significantly lower, and Expanded Prostate Cancer Index Composite urinary incontinence score (P <.05) in the sling group was higher than those in nonsling group, 4 weeks after RARP. In addition, mean pad weight gain on 1-hour pad test in the sling group was significantly smaller than that in the nonsling group, 4 weeks after RARP (P <.05). Both patient perception and objective data of urinary incontinence 4 weeks after RARP were better in the sling group than in the nonsling group. Valsalva maneuver during cystography demonstrated that the mean posterior urethrovesical angle in the sling group was smaller than that in the nonsling group (P <.001). AB - CONCLUSION: Bladder neck sling suspension technique is a simple and feasible procedure in RARP and can improve the early return of continence after RARP, although additional larger studies are required to confirm this finding. AB - Copyright © 2014 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(13)01423-4 DO - https://dx.doi.org/10.1016/j.urology.2013.09.059 PT - Journal Article PT - Randomized Controlled Trial ID - 24387929 [pubmed] ID - S0090-4295(13)01423-4 [pii] ID - 10.1016/j.urology.2013.09.059 [doi] PP - ppublish PH - 2013/07/09 [received] PH - 2013/09/11 [revised] PH - 2013/09/23 [accepted] LG - English EP - 20140101 DP - 2014 Mar DC - 20140303 EZ - 2014/01/07 06:00 DA - 2014/04/30 06:00 DT - 2014/01/07 06:00 YR - 2014 ED - 20140429 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24387929 <260. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23708138 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Richter M FA - Richter, Martinus IN - Richter, Martinus. Department for Foot and Ankle Surgery Rummelsberg and Nuremberg, Location Hospital Rummelsberg, Schwarzenbruck, Germany. info@martinusrichter.de TI - Computer aided surgery in foot and ankle: applications and perspectives. SO - International Orthopaedics. 37(9):1737-45, 2013 Sep AS - Int Orthop. 37(9):1737-45, 2013 Sep NJ - International orthopaedics PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - grf, 7705431 IO - Int Orthop PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764301 SB - Index Medicus CP - Germany MH - Ankle/pp [Physiopathology] MH - *Ankle/su [Surgery] MH - Biomechanical Phenomena MH - Feasibility Studies MH - Follow-Up Studies MH - Foot/pp [Physiopathology] MH - *Foot/su [Surgery] MH - Humans MH - Imaging, Three-Dimensional MH - Intraoperative Care MH - Prospective Studies MH - *Surgery, Computer-Assisted AB - PURPOSE: At the beginning of the twenty-first century, the computer has supplemented the possibilities of orthopaedic surgery. This article analyses the feasibility and potential clinical benefit of intraoperative three-dimensional imaging (3D), computer assisted surgery (CAS) and intraoperative pedography (IP) in foot and ankle surgery. AB - METHODS: The feasibility, accuracy and clinical benefit of 3D, CAS and IP were analysed in ongoing experimental and prospective studies at the institution in which the inventor of IP and principal user of 3D and CAS in foot and ankle surgery operates. AB - RESULTS: Three dimensional imaging: In approximately one third of the cases, reduction/correction and/or implant position was corrected after intraoperative 3D scan during the same procedure in different prospective, consecutive, non-controlled studies (Level III). CAS: CAS guidance for the correction of deformities of the ankle, hindfoot and midfoot/tarsometatarsal (TMT) joint provided higher accuracy, a faster correction process and better scores at a minimum follow-up of two years in comparison without CAS guidance in a single-centre matched-pair follow-up study (Level II). IP: Additional use of IP as the only difference between two groups with correction and/or arthrodesis at foot and/or ankle led to improved clinical outcome scores at a mean of two years follow-up in a prospective randomised controlled study (Level I). AB - CONCLUSIONS: Three dimensional imaging provides important information which could not be obtained from two-dimensional C-arm alone. The benefit of CAS is high when improved accuracy may lead to an improved clinical outcome. Intraoperative pedography is useful when intraoperative biomechanical assessment may lead to an immediate improvement of the achieved surgical result. ES - 1432-5195 IL - 0341-2695 DO - https://dx.doi.org/10.1007/s00264-013-1922-5 PT - Journal Article PT - Randomized Controlled Trial ID - 23708138 [pubmed] ID - 10.1007/s00264-013-1922-5 [doi] ID - PMC3764301 [pmc] PP - ppublish PH - 2013/04/26 [received] PH - 2013/04/26 [accepted] LG - English EP - 20130525 DP - 2013 Sep DC - 20130906 EZ - 2013/05/28 06:00 DA - 2014/04/30 06:00 DT - 2013/05/28 06:00 YR - 2013 ED - 20140429 RD - 20150426 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23708138 <261. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23989810 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Srivastava MC AU - Vesely MR AU - Lee JD AU - Lehr EJ AU - Wehman B AU - Bonaros N AU - Schachner T AU - Friedrich GJ AU - Zimrin DA AU - Bonatti JO FA - Srivastava, Mukta C FA - Vesely, Mark R FA - Lee, Jeffrey D FA - Lehr, Eric J FA - Wehman, Brody FA - Bonaros, Nikolaos FA - Schachner, Thomas FA - Friedrich, Guy J FA - Zimrin, David A FA - Bonatti, Johannes O IN - Srivastava, Mukta C. Division of Cardiology, University of Maryland Medical Center, Baltimore, MD 21201, USA. msrivast@medicine.umaryland.edu TI - Robotically assisted hybrid coronary revascularization: does sequence of intervention matter?. SO - Innovations: Technology & Techniques in Cardiothoracic & Vascular Surgery. 8(3):177-83, 2013 May-Jun AS - Innovations. 8(3):177-83, 2013 May-Jun NJ - Innovations (Philadelphia, Pa.) PI - Journal available in: Print PI - Citation processed from: Internet JC - 101257528 IO - Innovations (Phila) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - *Coronary Artery Bypass/mt [Methods] MH - Female MH - Humans MH - Male MH - Middle Aged MH - Minimally Invasive Surgical Procedures/mt [Methods] MH - *Percutaneous Coronary Intervention/mt [Methods] MH - *Robotics/mt [Methods] MH - Treatment Outcome AB - OBJECTIVE: Hybrid coronary revascularization (HCR) is a treatment strategy for the revascularization of multivessel coronary disease that combines the advantages of both minimally invasive surgical techniques and percutaneous coronary intervention (PCI). The optimal sequence by which revascularization should be accomplished has not been determined. We investigated clinical outcomes in a series of patients planned for HCR via robotically assisted totally endoscopic coronary artery bypass (TECAB) and standard PCI based on revascularization sequence. AB - METHODS: A total of 238 patients planned for HCR between 2001 and 2011 were divided into three groups based on treatment sequence: (a) TECAB before PCI, (b) PCI before TECAB, and (c) same-session procedure. Multiple procedural and clinical end points before discharge and up to 2 years after the procedure were compared between the three groups in an intention-to-treat analysis. Demographic features were reviewed to determine baseline differences between each group. AB - RESULTS: Of the 238 patients, 175 (73.5%) underwent TECAB before PCI, 38 patients (16.0%) underwent PCI before TECAB, and 25 (10.5%) underwent a simultaneous revascularization procedure. At baseline, the patients undergoing TECAB before PCI were significantly older. There was a significantly higher incidence of previous myocardial infarction in the PCI-first group (P < 0.001). There was a significant difference in intensive care unit (ICU) length of stay (LOS), with shorter ICU stays in the simultaneous revascularization group (P = 0.031) and shorter hospital LOS in the PCI before TECAB group (P = 0.021). AB - CONCLUSIONS: In conclusion, revascularization sequence did not dramatically impact clinical outcomes in our observational study. The patients undergoing PCI-first and same-session interventions had shorter hospital and ICU LOS compared with the patients undergoing surgery first. Our findings suggest that no revascularization approach is arbitrarily superior and that revascularization sequence should be individualized on the basis of patient presentation and anatomical considerations. ES - 1559-0879 IL - 1556-9845 DI - 01243895-201305000-00002 DO - https://dx.doi.org/10.1097/IMI.0b013e3182a2503a PT - Clinical Trial PT - Journal Article ID - 23989810 [pubmed] ID - 10.1097/IMI.0b013e3182a2503a [doi] ID - 01243895-201305000-00002 [pii] PP - ppublish LG - English DP - 2013 May-Jun DC - 20130830 EZ - 2013/08/31 06:00 DA - 2014/04/26 06:00 DT - 2013/08/31 06:00 YR - 2013 ED - 20140425 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23989810 <262. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24406108 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Garikipati NV AU - Mittal S AU - Chaudhry F AU - Musat DL AU - Sichrovsky T AU - Preminger M AU - Arshad A AU - Steinberg JS FA - Garikipati, Naga V FA - Mittal, Suneet FA - Chaudhry, Farooq FA - Musat, Dan L FA - Sichrovsky, Tina FA - Preminger, Mark FA - Arshad, Aysha FA - Steinberg, Jonathan S IN - Garikipati, Naga V. Division of Cardiology, Wright State University Boonshoft School of Medicine, Dayton, Ohio. IN - Mittal, Suneet. The Arrhythmia Institute, Valley Health System, Ridgewood, New Jersey; Columbia University College of Physicians and Surgeons, New York, New York. IN - Chaudhry, Farooq. Division of Cardiology, The Mount Sinai Hospital, New York, New York. IN - Musat, Dan L. The Arrhythmia Institute, Valley Health System, Ridgewood, New Jersey; Columbia University College of Physicians and Surgeons, New York, New York. IN - Sichrovsky, Tina. The Arrhythmia Institute, Valley Health System, Ridgewood, New Jersey; Columbia University College of Physicians and Surgeons, New York, New York. IN - Preminger, Mark. The Arrhythmia Institute, Valley Health System, Ridgewood, New Jersey; Columbia University College of Physicians and Surgeons, New York, New York. IN - Arshad, Aysha. The Arrhythmia Institute, Valley Health System, Ridgewood, New Jersey; Columbia University College of Physicians and Surgeons, New York, New York. IN - Steinberg, Jonathan S. The Arrhythmia Institute, Valley Health System, Ridgewood, New Jersey; Columbia University College of Physicians and Surgeons, New York, New York. Electronic address: steijo@valleyhealth.com. TI - Comparison of endovascular versus epicardial lead placement for resynchronization therapy. SO - American Journal of Cardiology. 113(5):840-4, 2014 Mar 01 AS - Am J Cardiol. 113(5):840-4, 2014 Mar 01 NJ - The American journal of cardiology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 3dq, 0207277 IO - Am. J. Cardiol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Aged, 80 and over MH - *Cardiac Resynchronization Therapy/mt [Methods] MH - Cardiac Resynchronization Therapy Devices/sn [Statistics & Numerical Data] MH - Coronary Sinus MH - Electrodes, Implanted/sn [Statistics & Numerical Data] MH - *Electrodes, Implanted MH - Endovascular Procedures MH - Female MH - *Heart Failure/th [Therapy] MH - Humans MH - Male MH - Middle Aged MH - Pericardium MH - Pilot Projects MH - *Prosthesis Implantation/mt [Methods] MH - Radiography, Interventional MH - Thoracoscopy MH - Ventricular Dysfunction, Left/th [Therapy] AB - Cardiac resynchronization therapy (CRT) has been shown to improve survival and symptoms in patients with severe left ventricular (LV) dysfunction, congestive heart failure, and prolonged QRS duration. LV lead placement is achieved by placing the lead in the coronary sinus, an endovascular approach, or by a minimally invasive robotic-assisted thoracoscopic epicardial approach. There are no data directly comparing the 2 methods. Patients eligible for CRT were randomized to the endovascular and epicardial arms. Coronary sinus lead placement was achieved using the standard technique, and epicardial leads were placed using a minimally invasive robotic-assisted thoracoscopic approach. The primary end point was a decrease in LV end-systolic volume index at 6 months. The secondary end points included 30-day mortality rate, measures of clinical improvement, 1-year electrical lead performance, and 1-year survival rate. The relative improvement of LV end-systolic volume index from baseline to 6 months was similar between the arms (28.8% for the transvenous [n = 12] vs 30.5% for the epicardial (n = 9) arm, p = 0.93). There were no significant differences in the secondary end points between the 2 groups. In conclusion, there were no differences in echocardiographic and clinical outcomes comparing a conventional endovascular approach versus robotic-assisted surgical epicardial LV lead placement for CRT in patients with heart failure. Surgical approaches are still a viable alternative when a transvenous procedure has failed or is not technically feasible. AB - Copyright © 2014 Elsevier Inc. All rights reserved. ES - 1879-1913 IL - 0002-9149 DI - S0002-9149(13)02385-0 DO - https://dx.doi.org/10.1016/j.amjcard.2013.11.040 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 24406108 [pubmed] ID - S0002-9149(13)02385-0 [pii] ID - 10.1016/j.amjcard.2013.11.040 [doi] PP - ppublish PH - 2013/08/06 [received] PH - 2013/11/08 [revised] PH - 2013/11/08 [accepted] LG - English EP - 20131212 DP - 2014 Mar 01 DC - 20140217 EZ - 2014/01/11 06:00 DA - 2014/04/22 06:00 DT - 2014/01/11 06:00 YR - 2014 ED - 20140421 RD - 20140217 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24406108 <263. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23965894 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Barbash GI AU - Friedman B AU - Glied SA AU - Steiner CA FA - Barbash, Gabriel I FA - Friedman, Bernard FA - Glied, Sherry A FA - Steiner, Claudia A IN - Barbash, Gabriel I. *Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel; +Robert F. Wagner School of Public Service, New York University, New York, NY; and ++US Agency for Healthcare Research and Quality, Rockville, MD. TI - Factors associated with adoption of robotic surgical technology in US hospitals and relationship to radical prostatectomy procedure volume. CM - Comment in: J Surg Oncol. 2015 Sep;112(3):239; PMID: 26250475 CM - Comment in: Ann Surg. 2014 Jan;259(1):7-9; PMID: 24326746 SO - Annals of Surgery. 259(1):1-6, 2014 Jan AS - Ann Surg. 259(1):1-6, 2014 Jan NJ - Annals of surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 67s, 0372354 IO - Ann. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Economic Competition MH - Hospitals/sn [Statistics & Numerical Data] MH - Humans MH - Male MH - Prostatectomy/mt [Methods] MH - *Prostatectomy/sn [Statistics & Numerical Data] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotics/sn [Statistics & Numerical Data] MH - Technology Transfer MH - United States AB - OBJECTIVE: Robotic technology has diffused rapidly despite high costs and limited additive reimbursement by major payers. We aimed to identify the factors associated with hospitals' decisions to adopt robotic technology and the consequences of these decisions. AB - METHODS: This observational study used data on hospitals and market areas from 2005 to 2009. Included were hospitals in census-based statistical areas within states in the State Inpatient Database that participated in the American Hospital Association annual surveys and performed radical prostatectomies. The likelihood that a hospital would acquire a robotic facility and the rates of radical prostatectomy relative to the prevalence of robots in geographic market areas were assessed using multivariable analysis. AB - RESULTS: Hospitals in areas where a higher proportion of other hospitals had already acquired a robot were more likely to acquire one (P=0.012), as were those with more than 300 beds (P<0.0001) and teaching hospitals (P<0.0001). There was a significant association between years with a robot and the change in the number of radical prostatectomies (P<0.0001). More radical prostatectomies were performed in areas where the number of robots per 100,000 men was higher (P<0.0001). Adding a single robot per 100,000 men in an area was associated with a 30% increase in the rate of radical prostatectomies. AB - CONCLUSIONS: Local area robot competition was associated with the rapid spread of robot technology in the United States. Significantly more radical prostatectomies were performed in hospitals with robots and in market areas of hospitals with robotic technology. ES - 1528-1140 IL - 0003-4932 DO - https://dx.doi.org/10.1097/SLA.0b013e3182a5c8b8 PT - Journal Article PT - Observational Study ID - 23965894 [pubmed] ID - 10.1097/SLA.0b013e3182a5c8b8 [doi] PP - ppublish LG - English DP - 2014 Jan DC - 20131211 EZ - 2013/08/23 06:00 DA - 2014/03/29 06:00 DT - 2013/08/24 06:00 YR - 2014 ED - 20140327 RD - 20151214 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23965894 <264. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24463657 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Anger JT AU - Mueller ER AU - Tarnay C AU - Smith B AU - Stroupe K AU - Rosenman A AU - Brubaker L AU - Bresee C AU - Kenton K FA - Anger, Jennifer T FA - Mueller, Elizabeth R FA - Tarnay, Christopher FA - Smith, Bridget FA - Stroupe, Kevin FA - Rosenman, Amy FA - Brubaker, Linda FA - Bresee, Catherine FA - Kenton, Kimberly IN - Anger, Jennifer T. Department of Surgery, Division of Urology, and the Biostatistics & Bioinformatics Research Center, Cedars-Sinai Medical Center, and the Department of Obstetrics/Gynecology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California; and the Departments of Obstetrics/Gynecology & Urology and Public Health Sciences, Loyola University Chicago Stritch School of Medicine, Maywood, and the Center of Innovation in Complex Chronic Healthcare, Hines VA Hospital, Hines, Illinois. TI - Robotic compared with laparoscopic sacrocolpopexy: a randomized controlled trial.[Erratum appears in Obstet Gynecol. 2014 Jul;124(1):165] CM - Comment in: Obstet Gynecol. 2014 Jun;123(6):1357-8; PMID: 24848908 CM - Comment in: Obstet Gynecol. 2014 Jan;123(1):3-4; PMID: 24463656 SO - Obstetrics & Gynecology. 123(1):5-12, 2014 Jan AS - Obstet Gynecol. 123(1):5-12, 2014 Jan NJ - Obstetrics and gynecology PI - Journal available in: Print PI - Citation processed from: Internet JC - oc2, 0401101 IO - Obstet Gynecol PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266590 OI - Source: NLM. NIHMS542699 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Female MH - Gynecologic Surgical Procedures/ec [Economics] MH - Gynecologic Surgical Procedures/sn [Statistics & Numerical Data] MH - *Gynecologic Surgical Procedures MH - Humans MH - Laparoscopy/ec [Economics] MH - Laparoscopy/sn [Statistics & Numerical Data] MH - *Laparoscopy MH - Middle Aged MH - *Pelvic Organ Prolapse/su [Surgery] MH - Robotics/ec [Economics] MH - Robotics/sn [Statistics & Numerical Data] MH - *Robotics MH - Treatment Outcome AB - OBJECTIVE: Laparoscopic and robotic sacrocolpopexy are widely used for pelvic organ prolapse (POP) treatment. Evidence comparing outcomes and costs is lacking. We compared costs and clinically relevant outcomes in women randomized to laparoscopic sacrocolpopexy compared with robotic sacrocolpopexy. AB - METHODS: Participants with symptomatic stage POP II or greater, including significant apical support loss, were randomized to either laparoscopic or robotic sacrocolpopexy. We compared surgical costs (including costs for robot, initial hospitalization) and rehospitalization within 6 weeks. Secondary outcomes included postoperative pain, POP quantification, symptom severity and quality of life, and adverse events. AB - RESULTS: We randomized 78 women (mean age 59 years): laparoscopic (n=38) and robotic (n=40). The robotic sacrocolpopexy group had higher initial hospital costs ($19,616 compared with $11,573, P<.001) and over 6 weeks, hospital costs remained higher for robotic sacrocolpopexy ($20,898 compared with $12,170, P<.001). When we excluded costs of robot purchase and maintenance, we did not detect a statistical difference in initial day of surgery costs of robotic compared with laparoscopic ($12,586 compared with $11,573; P=.160) or hospital costs over 6 weeks ($13,867 compared with $12,170; P=.060). The robotic group had longer operating room times (202.8 minutes compared with 178.4 minutes, P=.030) and higher pain scores 1 week after surgery (3.5+/-2.1 compared with 2.6+/-2.2; P=.044). There were no group differences in symptom bother by Pelvic Floor Distress Inventory, POP stage, or rate of adverse events. AB - CONCLUSION: Costs of robotic sacrocolpopexy are higher than laparoscopic, whereas short-term outcomes and complications are similar. Primary cost differences resulted from robot maintenance and purchase costs. AB - CLINICAL TRIAL REGISTRATION: Clinicaltrials.gov, www.clinicaltrials.gov, NCT01124916. AB - LEVEL OF EVIDENCE: I. ES - 1873-233X IL - 0029-7844 DI - 00006250-201401000-00003 DO - https://dx.doi.org/10.1097/AOG.0000000000000006 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, N.I.H., Extramural ID - 24463657 [pubmed] ID - 10.1097/AOG.0000000000000006 [doi] ID - 00006250-201401000-00003 [pii] ID - PMC4266590 [pmc] ID - NIHMS542699 [mid] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01124916 SA - ClinicalTrials.gov/NCT01124916 SL - https://clinicaltrials.gov/search/term=NCT01124916 SL - https://clinicaltrials.gov/search/term=NCT01124916 GI - No: RC1 EB010649 Organization: (EB) *NIBIB NIH HHS* Country: United States No: RC1 EB010649-01 Organization: (EB) *NIBIB NIH HHS* Country: United States LG - English DP - 2014 Jan DC - 20140127 EZ - 2014/01/28 06:00 DA - 2014/03/19 06:00 DT - 2014/01/28 06:00 YR - 2014 ED - 20140318 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24463657 <265. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24463657 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Anger JT AU - Mueller ER AU - Tarnay C AU - Smith B AU - Stroupe K AU - Rosenman A AU - Brubaker L AU - Bresee C AU - Kenton K FA - Anger, Jennifer T FA - Mueller, Elizabeth R FA - Tarnay, Christopher FA - Smith, Bridget FA - Stroupe, Kevin FA - Rosenman, Amy FA - Brubaker, Linda FA - Bresee, Catherine FA - Kenton, Kimberly IN - Anger, Jennifer T. Department of Surgery, Division of Urology, and the Biostatistics & Bioinformatics Research Center, Cedars-Sinai Medical Center, and the Department of Obstetrics/Gynecology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California; and the Departments of Obstetrics/Gynecology & Urology and Public Health Sciences, Loyola University Chicago Stritch School of Medicine, Maywood, and the Center of Innovation in Complex Chronic Healthcare, Hines VA Hospital, Hines, Illinois. TI - Robotic compared with laparoscopic sacrocolpopexy: a randomized controlled trial.[Erratum appears in Obstet Gynecol. 2014 Jul;124(1):165] CM - Comment in: Obstet Gynecol. 2014 Jun;123(6):1357-8; PMID: 24848908 CM - Comment in: Obstet Gynecol. 2014 Jan;123(1):3-4; PMID: 24463656 SO - Obstetrics & Gynecology. 123(1):5-12, 2014 Jan AS - Obstet Gynecol. 123(1):5-12, 2014 Jan NJ - Obstetrics and gynecology PI - Journal available in: Print PI - Citation processed from: Internet JC - oc2, 0401101 IO - Obstet Gynecol PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266590 OI - Source: NLM. NIHMS542699 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Female MH - Gynecologic Surgical Procedures/ec [Economics] MH - Gynecologic Surgical Procedures/sn [Statistics & Numerical Data] MH - *Gynecologic Surgical Procedures MH - Humans MH - Laparoscopy/ec [Economics] MH - Laparoscopy/sn [Statistics & Numerical Data] MH - *Laparoscopy MH - Middle Aged MH - *Pelvic Organ Prolapse/su [Surgery] MH - Robotics/ec [Economics] MH - Robotics/sn [Statistics & Numerical Data] MH - *Robotics MH - Treatment Outcome AB - OBJECTIVE: Laparoscopic and robotic sacrocolpopexy are widely used for pelvic organ prolapse (POP) treatment. Evidence comparing outcomes and costs is lacking. We compared costs and clinically relevant outcomes in women randomized to laparoscopic sacrocolpopexy compared with robotic sacrocolpopexy. AB - METHODS: Participants with symptomatic stage POP II or greater, including significant apical support loss, were randomized to either laparoscopic or robotic sacrocolpopexy. We compared surgical costs (including costs for robot, initial hospitalization) and rehospitalization within 6 weeks. Secondary outcomes included postoperative pain, POP quantification, symptom severity and quality of life, and adverse events. AB - RESULTS: We randomized 78 women (mean age 59 years): laparoscopic (n=38) and robotic (n=40). The robotic sacrocolpopexy group had higher initial hospital costs ($19,616 compared with $11,573, P<.001) and over 6 weeks, hospital costs remained higher for robotic sacrocolpopexy ($20,898 compared with $12,170, P<.001). When we excluded costs of robot purchase and maintenance, we did not detect a statistical difference in initial day of surgery costs of robotic compared with laparoscopic ($12,586 compared with $11,573; P=.160) or hospital costs over 6 weeks ($13,867 compared with $12,170; P=.060). The robotic group had longer operating room times (202.8 minutes compared with 178.4 minutes, P=.030) and higher pain scores 1 week after surgery (3.5+/-2.1 compared with 2.6+/-2.2; P=.044). There were no group differences in symptom bother by Pelvic Floor Distress Inventory, POP stage, or rate of adverse events. AB - CONCLUSION: Costs of robotic sacrocolpopexy are higher than laparoscopic, whereas short-term outcomes and complications are similar. Primary cost differences resulted from robot maintenance and purchase costs. AB - CLINICAL TRIAL REGISTRATION: Clinicaltrials.gov, www.clinicaltrials.gov, NCT01124916. AB - LEVEL OF EVIDENCE: I. ES - 1873-233X IL - 0029-7844 DI - 00006250-201401000-00003 DO - https://dx.doi.org/10.1097/AOG.0000000000000006 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, N.I.H., Extramural ID - 24463657 [pubmed] ID - 10.1097/AOG.0000000000000006 [doi] ID - 00006250-201401000-00003 [pii] ID - PMC4266590 [pmc] ID - NIHMS542699 [mid] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01124916 SL - https://clinicaltrials.gov/search/term=NCT01124916 GI - No: RC1 EB010649 Organization: (EB) *NIBIB NIH HHS* Country: United States No: RC1 EB010649-01 Organization: (EB) *NIBIB NIH HHS* Country: United States LG - English DP - 2014 Jan DC - 20140127 EZ - 2014/01/28 06:00 DA - 2014/03/19 06:00 DT - 2014/01/28 06:00 YR - 2014 ED - 20140318 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=24463657 <266. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23935818 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - de Sena DP AU - Fabricio DD AU - Lopes MH AU - da Silva VD FA - de Sena, David P FA - Fabricio, Daniela D FA - Lopes, Maria Helena I FA - da Silva, Vinicius D IN - de Sena, David P. Postgraduate Program in Health Sciences, Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil. TI - Computer-assisted teaching of skin flap surgery: validation of a mobile platform software for medical students. SO - PLoS ONE [Electronic Resource]. 8(7):e65833, 2013 AS - PLoS ONE. 8(7):e65833, 2013 NJ - PloS one PI - Journal available in: Electronic-Print PI - Citation processed from: Internet JC - 101285081 IO - PLoS ONE PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720809 SB - Index Medicus CP - United States MH - Animals MH - Brazil MH - Checklist MH - *Computer-Assisted Instruction MH - *Dermatologic Surgical Procedures/ed [Education] MH - *Education, Medical MH - Educational Measurement MH - Female MH - Humans MH - Male MH - Random Allocation MH - Reproducibility of Results MH - *Software MH - *Students, Medical MH - *Surgical Flaps AB - The purpose of this study was to develop and validate a multimedia software application for mobile platforms to assist in the teaching and learning process of design and construction of a skin flap. Traditional training in surgery is based on learning by doing. Initially, the use of cadavers and animal models appeared to be a valid alternative for training. However, many conflicts with these training models prompted progression to synthetic and virtual reality models. Fifty volunteer fifth- and sixth-year medical students completed a pretest and were randomly allocated into two groups of 25 students each. The control group was exposed for 5 minutes to a standard text-based print article, while the test group used multimedia software describing how to fashion a rhomboid flap. Each group then performed a cutaneous flap on a training bench model while being evaluated by three blinded BSPS (Brazilian Society of Plastic Surgery) board-certified surgeons using the OSATS (Objective Structured Assessment of Technical Skill) protocol and answered a post-test. The text-based group was then tested again using the software. The computer-assisted learning (CAL) group had superior performance as confirmed by checklist scores (p<0.002), overall global assessment (p = 0.017) and post-test results (p<0.001). All participants ranked the multimedia method as the best study tool. CAL learners exhibited better subjective and objective performance when fashioning rhomboid flaps as compared to those taught with standard print material. These findings indicate that students preferred to learn using the multimedia method. ES - 1932-6203 IL - 1932-6203 DI - PONE-D-13-14530 DO - https://dx.doi.org/10.1371/journal.pone.0065833 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't PT - Validation Studies ID - 23935818 [pubmed] ID - 10.1371/journal.pone.0065833 [doi] ID - PONE-D-13-14530 [pii] ID - PMC3720809 [pmc] PP - epublish PH - 2013/04/01 [received] PH - 2013/04/29 [accepted] LG - English EP - 20130723 DP - 2013 DC - 20130812 EZ - 2013/08/13 06:00 DA - 2014/03/07 06:00 DT - 2013/08/13 06:00 YR - 2013 ED - 20140305 RD - 20150423 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23935818 <267. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23812769 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Alvarado MD AU - Mohan AJ AU - Esserman LJ AU - Park CC AU - Harrison BL AU - Howe RJ AU - Thorsen C AU - Ozanne EM FA - Alvarado, Michael D FA - Mohan, Aron J FA - Esserman, Laura J FA - Park, Catherine C FA - Harrison, Brittany L FA - Howe, Rebecca J FA - Thorsen, Cristina FA - Ozanne, Elissa M IN - Alvarado, Michael D. Department of Surgery, UCSF Comprehensive Cancer Center, San Francisco, CA, USA. michael.alvarado@ucsfmedctr.org TI - Cost-effectiveness analysis of intraoperative radiation therapy for early-stage breast cancer. SO - Annals of Surgical Oncology. 20(9):2873-80, 2013 Sep AS - Ann Surg Oncol. 20(9):2873-80, 2013 Sep NJ - Annals of surgical oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - b9r, 9420840 IO - Ann. Surg. Oncol. SB - Index Medicus CP - United States MH - *Brachytherapy/ec [Economics] MH - Brachytherapy/mo [Mortality] MH - *Breast Neoplasms/ec [Economics] MH - Breast Neoplasms/mo [Mortality] MH - Breast Neoplasms/rt [Radiotherapy] MH - Combined Modality Therapy MH - *Cost-Benefit Analysis MH - Female MH - Follow-Up Studies MH - Humans MH - Intraoperative Care MH - Lymphatic Metastasis MH - *Markov Chains MH - Middle Aged MH - *Neoplasm Recurrence, Local/ec [Economics] MH - Neoplasm Recurrence, Local/mo [Mortality] MH - Neoplasm Recurrence, Local/rt [Radiotherapy] MH - Neoplasm Staging MH - Prognosis MH - Quality of Life MH - *Radiotherapy, Adjuvant/ec [Economics] MH - Radiotherapy, Adjuvant/mo [Mortality] MH - Survival Rate AB - BACKGROUND: Shortened courses of radiation therapy have been shown to be similarly effective to whole-breast external-beam radiation therapy (WB-EBRT) in terms of local control. We sought to analyze, from a societal perspective, the cost-effectiveness of two radiation strategies for early-stage invasive breast cancer: single-dose intraoperative radiation therapy (IORT) and the standard 6-week course of WB-EBRT. AB - METHODS: We developed a Markov decision-analytic model to evaluate these treatment strategies in terms of life expectancy, quality-adjusted life years (QALYs), costs, and the incremental cost-effectiveness ratio over 10 years. AB - RESULTS: IORT single-dose intraoperative radiation therapy was the dominant, more cost-effective strategy, providing greater quality-adjusted life years at a decreased cost compared with 6-week WB-EBRT. The model was sensitive to health state utilities and recurrence rates, but not costs. IORT was either the preferred or dominant strategy across all sensitivity analyses. The two-way sensitivity analyses demonstrate the need to accurately determine utility values for the two forms of radiation treatment and to avoid indiscriminate use of IORT. AB - CONCLUSIONS: With less cost and greater QALYs than WB-EBRT, IORT is the more valuable strategy. IORT offers a unique example of new technology that is less costly than the current standard of care option but offers similar efficacy. Even when considering the capital investment for the equipment ($425 K, low when compared with the investments required for robotic surgery or high-dose-rate brachytherapy), which could be recouped after 3-4 years conservatively, these results support IORT as a change in practice for treating early-stage invasive breast cancer. ES - 1534-4681 IL - 1068-9265 DO - https://dx.doi.org/10.1245/s10434-013-2997-3 PT - Journal Article PT - Randomized Controlled Trial ID - 23812769 [pubmed] ID - 10.1245/s10434-013-2997-3 [doi] PP - ppublish PH - 2012/09/28 [received] LG - English EP - 20130629 DP - 2013 Sep DC - 20130805 EZ - 2013/07/02 06:00 DA - 2014/03/07 06:00 DT - 2013/07/03 06:00 YR - 2013 ED - 20140305 RD - 20130805 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23812769 <268. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24327328 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kang CM AU - Chung YE AU - Jung MJ AU - Hwang HK AU - Choi SH AU - Lee WJ FA - Kang, C M FA - Chung, Y E FA - Jung, M J FA - Hwang, H K FA - Choi, S H FA - Lee, W J IN - Kang, C M. Department of Surgery, Yonsei University College of Medicine, Seoul, Korea; Department of Pancreaticobiliary Cancer Clinic, Institute of Gastroenterology, Severance Hospital, Seoul, Korea. TI - Splenic vein thrombosis and pancreatic fistula after minimally invasive distal pancreatectomy. CM - Comment in: Br J Surg. 2014 Jan;101(2):119-20; PMID: 24375302 SO - British Journal of Surgery. 101(2):114-9, 2014 Jan AS - Br J Surg. 101(2):114-9, 2014 Jan NJ - The British journal of surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - b34, 0372553 IO - Br J Surg SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - Female MH - Humans MH - *Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - Organ Sparing Treatments MH - *Pancreatectomy/ae [Adverse Effects] MH - Pancreatectomy/mt [Methods] MH - *Pancreatic Fistula/et [Etiology] MH - Pancreatic Neoplasms/su [Surgery] MH - Pancreatitis/su [Surgery] MH - Platelet Count MH - Retrospective Studies MH - *Robotics MH - Splenectomy/ae [Adverse Effects] MH - *Splenic Vein MH - *Venous Thrombosis/et [Etiology] AB - BACKGROUND: This study aimed to investigate the clinical relevance of splenic vein thrombosis (SVT) in the splenic vein remnant following minimally invasive distal pancreatosplenectomy (DPS). AB - METHODS: Medical records of patients who underwent laparoscopic or robotic distal pancreatectomy (DP) with or without splenectomy between January 2006 and August 2012 were reviewed. Rates of SVT and clinically relevant postoperative pancreatic fistula (POPF) were compared in a group of patients undergoing DPS and a group having spleen-preserving DP. AB - RESULTS: Seventy-nine patients had minimally invasive DP, of whom 38 (48 per cent) developed SVT in the splenic vein remnant. DPS was associated with POPF (P = 0.001) and SVT (P < 0.001). SVT length was closely related to the amount of peripancreatic fluid collection (P = 0.025) and POPF (P = 0.045). In a comparison of splenic vessel-sacrificing, spleen-preserving DP and DPS, postoperative platelet count was significantly higher in the DPS group (P < 0.001). In addition, grade of SVT (P = 0.092) and POPF (P = 0.065) tended to be associated with DPS, suggesting that SVT may be related to both splenectomy and POPF. AB - CONCLUSION: Minimally invasive DPS is associated with SVT and POPF. Preservation of the spleen should be considered when treating patients with benign and borderline malignant tumours of the distal pancreas. AB - Copyright © 2013 BJS Society Ltd. Published by John Wiley & Sons Ltd. ES - 1365-2168 IL - 0007-1323 DO - https://dx.doi.org/10.1002/bjs.9366 PT - Journal Article PT - Observational Study ID - 24327328 [pubmed] ID - 10.1002/bjs.9366 [doi] PP - ppublish PH - 2013/09/30 [accepted] LG - English EP - 20131210 DP - 2014 Jan DC - 20131230 EZ - 2013/12/12 06:00 DA - 2014/02/19 06:00 DT - 2013/12/12 06:00 YR - 2014 ED - 20140218 RD - 20131230 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24327328 <269. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23709426 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Park B AU - Jeong BC AU - Jeon SS AU - Lee HM AU - Choi HY AU - Seo SI FA - Park, Bumsoo FA - Jeong, Byong Chang FA - Jeon, Seong Soo FA - Lee, Hyun Moo FA - Choi, Han Yong FA - Seo, Seong Il IN - Park, Bumsoo. Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Korea. TI - Pure laparoscopic radical cystectomy with ileal conduit: a single surgeon's mid-term outcomes. SO - Yonsei Medical Journal. 54(4):912-20, 2013 Jul AS - Yonsei Med J. 54(4):912-20, 2013 Jul NJ - Yonsei medical journal PI - Journal available in: Print PI - Citation processed from: Internet JC - xrr, 0414003 IO - Yonsei Med. J. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663232 SB - Index Medicus CP - Korea (South) MH - Aged MH - Aged, 80 and over MH - Blood Loss, Surgical MH - *Cystectomy/mt [Methods] MH - Female MH - Humans MH - Length of Stay MH - Lymph Node Excision MH - Male MH - Middle Aged MH - Operative Time MH - Postoperative Complications/et [Etiology] MH - Postoperative Period MH - Treatment Outcome MH - Urinary Bladder Neoplasms/pa [Pathology] MH - *Urinary Bladder Neoplasms/su [Surgery] MH - *Urinary Diversion/mt [Methods] KW - Urinary bladder neoplasms; cystectomy; laparoscopic surgery AB - PURPOSE: The use of laparoscopic radical cystectomy (LRC) for muscle-invasive bladder cancer is not yet widespread because of the technical difficulties of the procedure and the lengthy operating time. In this study, we report a single surgeon's experience with LRC. AB - MATERIALS AND METHODS: Thirty patients (25 men and 5 women) with bladder cancer underwent LRC and ileal conduit by a single surgeon between November 2007 and May 2011. An extracorporeal urinary diversion was performed through 5-6 cm midline incision for specimen extraction. AB - RESULTS: The median operating time and estimated blood loss were 527.5 minutes and 275 mL, respectively. There was no conversion to open surgery. The median time to oral intake and postoperative hospital stay were 5 days and 12 days, respectively. The rates of immediate, early postoperative and late postoperative complication were 3.3%, 20% and 20%, respectively. With 16 months of median follow- up, the overall and recurrence-free survival rates were 70% and 56.7%, respectively. AB - CONCLUSION: LRC is feasible for the management of invasive bladder cancer and, with appropriate patient selection, can be a good alternative to open or robot-assisted radical cystectomy in the era of robot-assisted surgery. ES - 1976-2437 IL - 0513-5796 DI - 201307912 DO - https://dx.doi.org/10.3349/ymj.2013.54.4.912 PT - Clinical Trial PT - Journal Article ID - 23709426 [pubmed] ID - 201307912 [pii] ID - 10.3349/ymj.2013.54.4.912 [doi] ID - PMC3663232 [pmc] PP - ppublish LG - English DP - 2013 Jul DC - 20130527 EZ - 2013/05/28 06:00 DA - 2014/01/28 06:00 DT - 2013/05/28 06:00 YR - 2013 ED - 20140127 RD - 20150426 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23709426 <270. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23823810 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Wang Y AU - Wang G AU - Gao CQ FA - Wang, Yao FA - Wang, Gang FA - Gao, Chang-qing IN - Wang, Yao. Department of Cardiovascular Surgery, Chinese People's Liberation Army General Hospital, Beijing 100853, China. TI - Ultrasound-guided cannulation of the internal jugular vein in robotic cardiac surgery. SO - Chinese Medical Journal. 126(13):2414-7, 2013 Jul AS - Chin Med J. 126(13):2414-7, 2013 Jul NJ - Chinese medical journal PI - Journal available in: Print PI - Citation processed from: Internet JC - 0005256, d3b, 7513795 IO - Chin. Med. J. SB - Index Medicus CP - China MH - Adult MH - Aged MH - *Cardiac Surgical Procedures/mt [Methods] MH - Cardiopulmonary Bypass MH - Carotid Arteries/dg [Diagnostic Imaging] MH - *Catheterization, Central Venous/mt [Methods] MH - Female MH - Humans MH - *Jugular Veins/dg [Diagnostic Imaging] MH - Male MH - Middle Aged MH - Prospective Studies MH - *Robotics MH - *Ultrasonography, Interventional/mt [Methods] AB - BACKGROUND: Robotic assisted minimally invasive cardiac sugery is a new technique that uses small port sites and peripheral vessel cannulation for cardiopulmonary bypass (CPB) has been used. The right internal jugular vein (IJV) is commonly used for intraoperative venous access to the central circulation and identified with an external landmark. Previous studies have demonstrated the superiority of ultrasound guidance over external landmark technique in anaesthetic and intensive care settings. The aim of the present study was to delineate the utility of ultrasound-guided cannulation of the IJV during establishment of peripheral CPB in robotic cardiac surgery. AB - METHODS: We prospectively studied 296 adult patients undergoing ultrasound-guided right IJV cannulation during establishment of peripheral CPB in robotic cardiac surgery at our institute from January 2007 to October 2012 (ultrasound group). The success rate, the first attempt success rate, access time and the complication rate of ultrasound-guided method were compared with the landmark-guided method used for 302 historical control patients (landmark group). AB - RESULTS: In the ultrasound group, 296 consecutive adult patients underwent ultrasound-guided right IJV cannulation during establishment of peripheral CPB in robotic cardiac surgery. In the landmark group, 302 patients underwent right IJV cannulation using the landmark-guided technique. The success rate and the frst attempt success rate in the ultrasound group were significantly higher than that in the landmark group (100% vs. 88.1%, P < 0.000 and 98.6% vs. 38.4%, P < 0.000). Average access time in the ultrasound group was shorter than that in the landmark group ((6.3 +/- 13.6) seconds; interquartile range (4 - 62) seconds vs. (44.5 +/- 129.5) seconds; interquartile range (5 - 986) seconds). The complication rate in the ultrasound group was significantly lower than that in the landmark group (0.3% vs. 8.3%, P < 0.000). AB - CONCLUSION: Compared with the landmark-guided approach, ultrasound-guided cannulation of the right IJV significantly improves success rate, decreases access time and reduces complication rate during establishment of peripheral CPB in robotic cardiac surgery. IS - 0366-6999 IL - 0366-6999 PT - Clinical Trial PT - Journal Article ID - 23823810 [pubmed] PP - ppublish LG - English DP - 2013 Jul DC - 20130704 EZ - 2013/07/05 06:00 DA - 2014/01/24 06:00 DT - 2013/07/05 06:00 YR - 2013 ED - 20140123 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23823810 <271. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 24089234 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Akin Y AU - Avci E AU - Gulmez H AU - Akand M AU - Akif Ciftcioglu M AU - Bassorgun I AU - Erdogru T FA - Akin, Y FA - Avci, E FA - Gulmez, H FA - Akand, M FA - Akif Ciftcioglu, M FA - Bassorgun, I FA - Erdogru, T IN - Akin, Y. Department of Urology, Erzincan University School of Medicine, Erzincan, Turkey. yigitakin@yahoo.com. TI - Indications for intraoperative frozen section in robot assisted radical prostatectomy: a pilot study. SO - European Review for Medical & Pharmacological Sciences. 17(18):2523-9, 2013 Sep AS - Eur Rev Med Pharmacol Sci. 17(18):2523-9, 2013 Sep NJ - European review for medical and pharmacological sciences PI - Journal available in: Print PI - Citation processed from: Print JC - cyu, 9717360 IO - Eur Rev Med Pharmacol Sci SB - Index Medicus CP - Italy MH - Aged MH - *Frozen Sections MH - Humans MH - Laparoscopy MH - Male MH - Middle Aged MH - Pilot Projects MH - Prostate/dg [Diagnostic Imaging] MH - Prostate/pa [Pathology] MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotics/mt [Methods] MH - Ultrasonography AB - INTRODUCTION: To evaluate indications for intraoperative frozen section (IFS) during robot assisted laparoscopic radical prostatectomy (RALRP) in our series. AB - PATIENTS AND METHODS: Prospectively documented 80 patients with prostate cancer (PCa) who underwent RALRP were evaluated between June 2010 and July 2012. Patients were divided into 2 groups according to whether systematically IFS was performed or not. Group 1 (n=66) consisted of patients on whom systematic IFS was performed, Group 2 (n=14) consisted of patients on whom IFS was not performed. All recorded data evaluated and statistical analyses were performed for determining indications and predictive factors for IFS during RALRP. All patients were operated by single surgeon and IFS, pathological assessments were performed by experienced uro-pathologist. Statistical significant p value was p < 0.05. AB - RESULTS: Mean follow-up was 15+/-6 (25-4) months. Pre-operative prostate volume in trans- rectal ultrasonography (TRUS) was statistically higher in Group 1 than Group 2 (p = 0.037). The other parameters were statistically similar in both groups. According to outcomes of our study IFS was a dependent factor for positive surgical margin. Additionally, the cut off value of prostate volume in TRUS for IFS was 55.5 cc for IFS. AB - CONCLUSIONS: Preoperative measured prostate volume in TRUS may be an indicator of IFS. Therefore, more accurate information may be given to patients with prostate cancer (Pca) before RALRP by using preoperative prostate volume in TRUS. IS - 1128-3602 IL - 1128-3602 DI - 5234 PT - Controlled Clinical Trial PT - Journal Article ID - 24089234 [pubmed] PP - ppublish LG - English DP - 2013 Sep DC - 20131003 EZ - 2013/10/04 06:00 DA - 2014/01/17 06:00 DT - 2013/10/04 06:00 YR - 2013 ED - 20140116 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=24089234 <272. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23871948 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Mendise TJ AU - Roulette GD AU - von Gruenigen VE FA - Mendise, Thomas J FA - Roulette, G Dante FA - von Gruenigen, Vivian E IN - Mendise, Thomas J. Chief of Robotic Surgery Summa Health System, Summa Akron City Hospital, Medical Director, Women's Service Line, Summa Health System, Summa Akron City Hospital, Medical Building, 2nd Floor, 525 East Market St., Akron, OH 44304. TI - A randomized trial comparing conventional and robotically assisted total laparoscopic hysterectomy. CM - Comment in: Am J Obstet Gynecol. 2013 Dec;209(6):594-5; PMID: 23871949 CM - Comment on: Am J Obstet Gynecol. 2013 May;208(5):368.e1-7; PMID: 23395927 SO - American Journal of Obstetrics & Gynecology. 209(6):593-4, 2013 Dec AS - Am J Obstet Gynecol. 209(6):593-4, 2013 Dec NJ - American journal of obstetrics and gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 3ni, 0370476 IO - Am. J. Obstet. Gynecol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Female MH - Humans MH - *Hysterectomy/mt [Methods] MH - *Laparoscopy/mt [Methods] MH - *Robotics MH - *Uterine Diseases/su [Surgery] ES - 1097-6868 IL - 0002-9378 DI - S0002-9378(13)00740-0 DO - https://dx.doi.org/10.1016/j.ajog.2013.07.008 PT - Comment PT - Letter ID - 23871948 [pubmed] ID - S0002-9378(13)00740-0 [pii] ID - 10.1016/j.ajog.2013.07.008 [doi] PP - ppublish PH - 2013/05/29 [received] PH - 2013/07/10 [accepted] LG - English EP - 20130716 DP - 2013 Dec DC - 20131125 EZ - 2013/07/23 06:00 DA - 2014/01/16 06:00 DT - 2013/07/23 06:00 YR - 2013 ED - 20140115 RD - 20141106 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23871948 <273. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23508922 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hanna EM AU - Rozario N AU - Rupp C AU - Sindram D AU - Iannitti DA AU - Martinie JB FA - Hanna, Erin M FA - Rozario, Nigel FA - Rupp, Christopher FA - Sindram, David FA - Iannitti, David A FA - Martinie, John B IN - Hanna, Erin M. Department of General Surgery, Division of Hepatobiliary and Pancreatic Surgery, Carolinas Medical Center, Charlotte, NC, USA. TI - Robotic hepatobiliary and pancreatic surgery: lessons learned and predictors for conversion. SO - The International Journal Of Medical Robotics + Computer Assisted Surgery: MRCAS. 9(2):152-9, 2013 Jun AS - Int J Med Robot. 9(2):152-9, 2013 Jun NJ - The international journal of medical robotics + computer assisted surgery : MRCAS PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101250764 IO - Int J Med Robot SB - Index Medicus CP - England MH - *Biliary Tract Surgical Procedures/ut [Utilization] MH - *Blood Loss, Surgical/sn [Statistics & Numerical Data] MH - *Blood Transfusion/sn [Statistics & Numerical Data] MH - Female MH - *Hepatectomy/ut [Utilization] MH - Humans MH - Male MH - Middle Aged MH - North Carolina/ep [Epidemiology] MH - *Pancreatectomy/ut [Utilization] MH - Prevalence MH - Risk Factors MH - *Robotics/ut [Utilization] MH - *Surgery, Computer-Assisted/ut [Utilization] MH - Treatment Outcome AB - BACKGROUND: The use of surgical robots has slowly gained an increasing presence in the realm of hepatobiliary and pancreatic (HPB) surgery. With additional experience, anecdotal evidence has been useful in guiding patient selection for complex robotic procedures. In the following analysis, we reviewed our case series and looked for predictors of conversion in robotic HPB surgery. AB - METHODS: We retrospectively reviewed all patients who underwent robotic HPB procedures by a single surgeon at two institutions during March 2006-June 2012. Patient demographics, operative data, procedure type and conversion information were recorded. Trends were analysed for indications for conversion. A subset analysis of robotic-assisted laparoscopic distal pancreatomy was performed and compared with laparoscopic and open distal pancreatectomy during the same time period by the same surgeon. AB - RESULTS: During this time period, 77 patients underwent robotic hepatobiliary and pancreatic procedures. All procedures were performed by a single surgeon (J.M.) and included 38 males (49%) and 39 females (51%). Median age was 59 and the majority of patients were ASA class III. There were 24 conversions, which decreased in frequency from 2009 (7) to 2011 (3). Reasons for conversion included significant obesity and technical difficulty. Patients with conversions had more intraoperative blood loss (966 vs 176 ml), more frequently received transfusion (29% vs 2%) and were more likely to have postoperative intensive care. Overall length of stay was longer following conversion (8.3 vs 5.6 days). AB - CONCLUSIONS: Robotic-assisted hepatobiliary and pancreatic procedures are often extremely complex, with a significant learning curve. Recognizing factors that prohibit successful completion of a robotic-assisted surgical procedure is key for patient safety. Careful patient selection in the appropriate settings facilitates the maximal benefit of robotic-assisted complex HPB surgery. AB - Copyright © 2013 John Wiley & Sons, Ltd. ES - 1478-596X IL - 1478-5951 DO - https://dx.doi.org/10.1002/rcs.1492 PT - Clinical Trial PT - Journal Article ID - 23508922 [pubmed] ID - 10.1002/rcs.1492 [doi] PP - ppublish PH - 2013/01/25 [accepted] LG - English EP - 20130319 DP - 2013 Jun DC - 20130611 EZ - 2013/03/20 06:00 DA - 2014/01/09 06:00 DT - 2013/03/20 06:00 YR - 2013 ED - 20140108 RD - 20130611 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23508922 <274. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23408585 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Moreno-Sierra J AU - Castillon-Vela I AU - Ortiz-Oshiro E AU - Galante-Romo I AU - Fernandez-Perez C AU - Senovilla-Perez JL AU - Casado-Varela J AU - Garde-Garcia H AU - Chavez-Roa C AU - Vera-Gonzalez V FA - Moreno-Sierra, Jesus FA - Castillon-Vela, Ignacio FA - Ortiz-Oshiro, Elena FA - Galante-Romo, Isabel FA - Fernandez-Perez, Cristina FA - Senovilla-Perez, Jose L FA - Casado-Varela, Javier FA - Garde-Garcia, Hector FA - Chavez-Roa, Cesar FA - Vera-Gonzalez, Vicente IN - Moreno-Sierra, Jesus. Urology Department, Instituto de Investigacion Sanitaria, Hospital Clinico San Carlos, Universidad Complutense, Madrid, Spain. dr_jmoreno@hotmail.com TI - Robotic Anderson-Hynes dismembered pyeloplasty: initial experience. [Review] SO - The International Journal Of Medical Robotics + Computer Assisted Surgery: MRCAS. 9(2):127-33, 2013 Jun AS - Int J Med Robot. 9(2):127-33, 2013 Jun NJ - The international journal of medical robotics + computer assisted surgery : MRCAS PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101250764 IO - Int J Med Robot SB - Index Medicus CP - England MH - Adult MH - *Decompression, Surgical/mt [Methods] MH - Female MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - *Nephrectomy/mt [Methods] MH - Pilot Projects MH - *Reconstructive Surgical Procedures/mt [Methods] MH - *Robotics/mt [Methods] MH - *Surgery, Computer-Assisted/mt [Methods] MH - Treatment Outcome MH - Ureteral Obstruction/pa [Pathology] MH - *Ureteral Obstruction/su [Surgery] MH - Young Adult AB - INTRODUCTION: The introduction of the da Vinci() robotic system in 2000 has been a new step forward in the treatment of ureteropelvic junction obstruction (UPJO). The aim of this study was to analyse our initial experience with robot-assisted dismembered Anderson-Hynes pyeloplasty and to perform a bibliographic review on the topic. AB - PATIENTS AND METHODS: We performed 11 robot-assisted pyeloplasties between March 2007 and April 2011. UPJO diagnosis was made on clinical presentation and imaging techniques (CT scan and intravenous urography). All patients underwent basal and diuretic isotopic renograms to evaluate the degree of obstruction and impaired renal function. Median follow-up was 10 (range 1-26) months. AB - RESULTS: Mean patient age was 38.8 (range 23-62) years. There were six women (55%) and five men (45%). All cases were primary surgeries. In four patients the cause of UPJO was a crossing vessel; the other seven patients had intrinsic obstruction. One case was associated with extraction of a calyceal lithiasis. Mean operative time was 189.4min (125-270min). Average time from robotic arms docking was 116.5 (range 55-180) min. Average hospital stay was 4.18 (range 2-8) days. Conversion to open or laparoscopic surgery was not necessary in any case and there were no postoperative complications. Postoperative radiological evaluation and renograms showed good results in all cases. AB - CONCLUSIONS: Robotic surgery offers better ergonomics, enhanced three-dimensional (3D) vision and more precise movements, easing intracorporeal suturing.These advantages make robotic pyeloplasty a reproducible technique that combines the high success rates of open surgery and the benefits of laparoscopic surgery. AB - Copyright © 2013 John Wiley & Sons, Ltd. ES - 1478-596X IL - 1478-5951 DO - https://dx.doi.org/10.1002/rcs.1473 PT - Clinical Trial PT - Journal Article PT - Review ID - 23408585 [pubmed] ID - 10.1002/rcs.1473 [doi] PP - ppublish PH - 2012/10/31 [accepted] LG - English EP - 20130214 DP - 2013 Jun DC - 20130611 EZ - 2013/02/15 06:00 DA - 2014/01/09 06:00 DT - 2013/02/15 06:00 YR - 2013 ED - 20140108 RD - 20130611 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23408585 <275. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23910887 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Chowriappa AJ AU - Shi Y AU - Raza SJ AU - Ahmed K AU - Stegemann A AU - Wilding G AU - Kaouk J AU - Peabody JO AU - Menon M AU - Hassett JM AU - Kesavadas T AU - Guru KA FA - Chowriappa, Ashirwad J FA - Shi, Yi FA - Raza, Syed Johar FA - Ahmed, Kamran FA - Stegemann, Andrew FA - Wilding, Gregory FA - Kaouk, Jihad FA - Peabody, James O FA - Menon, Mani FA - Hassett, James M FA - Kesavadas, Thenkurussi FA - Guru, Khurshid A IN - Chowriappa, Ashirwad J. Roswell Park Cancer Institute, Buffalo, New York; University at Buffalo, Buffalo, New York. TI - Development and validation of a composite scoring system for robot-assisted surgical training--the Robotic Skills Assessment Score. SO - Journal of Surgical Research. 185(2):561-9, 2013 Dec AS - J Surg Res. 185(2):561-9, 2013 Dec NJ - The Journal of surgical research PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - k7b, 0376340 IO - J. Surg. Res. SB - Index Medicus CP - United States MH - Adult MH - Competency-Based Education/mt [Methods] MH - Competency-Based Education/st [Standards] MH - Computer Simulation/st [Standards] MH - *Education, Medical, Graduate/mt [Methods] MH - *Education, Medical, Graduate/st [Standards] MH - *Educational Measurement/mt [Methods] MH - *Educational Measurement/st [Standards] MH - Female MH - *General Surgery/ed [Education] MH - Humans MH - Internship and Residency/mt [Methods] MH - Internship and Residency/st [Standards] MH - Male MH - Prospective Studies MH - *Robotics/ed [Education] MH - User-Computer Interface KW - Robotic skills assessment; Robotic training; Score; Scoring system; Surgical training AB - BACKGROUND: A standardized scoring system does not exist in virtual reality-based assessment metrics to describe safe and crucial surgical skills in robot-assisted surgery. This study aims to develop an assessment score along with its construct validation. AB - MATERIALS AND METHODS: All subjects performed key tasks on previously validated Fundamental Skills of Robotic Surgery curriculum, which were recorded, and metrics were stored. After an expert consensus for the purpose of content validation (Delphi), critical safety determining procedural steps were identified from the Fundamental Skills of Robotic Surgery curriculum and a hierarchical task decomposition of multiple parameters using a variety of metrics was used to develop Robotic Skills Assessment Score (RSA-Score). Robotic Skills Assessment mainly focuses on safety in operative field, critical error, economy, bimanual dexterity, and time. Following, the RSA-Score was further evaluated for construct validation and feasibility. Spearman correlation tests performed between tasks using the RSA-Scores indicate no cross correlation. Wilcoxon rank sum tests were performed between the two groups. AB - RESULTS: The proposed RSA-Score was evaluated on non-robotic surgeons (n = 15) and on expert-robotic surgeons (n = 12). The expert group demonstrated significantly better performance on all four tasks in comparison to the novice group. Validation of the RSA-Score in this study was carried out on the Robotic Surgical Simulator. AB - CONCLUSION: The RSA-Score is a valid scoring system that could be incorporated in any virtual reality-based surgical simulator to achieve standardized assessment of fundamental surgical tents during robot-assisted surgery. AB - Copyright © 2013 Elsevier Inc. All rights reserved. ES - 1095-8673 IL - 0022-4804 DI - S0022-4804(13)00680-X DO - https://dx.doi.org/10.1016/j.jss.2013.06.054 PT - Journal Article PT - Observational Study PT - Validation Studies ID - 23910887 [pubmed] ID - S0022-4804(13)00680-X [pii] ID - 10.1016/j.jss.2013.06.054 [doi] PP - ppublish PH - 2013/05/01 [received] PH - 2013/06/10 [revised] PH - 2013/06/24 [accepted] LG - English EP - 20130718 DP - 2013 Dec DC - 20131112 EZ - 2013/08/06 06:00 DA - 2014/01/08 06:00 DT - 2013/08/06 06:00 YR - 2013 ED - 20140107 RD - 20150708 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23910887 <276. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23114476 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Trastulli S AU - Desiderio J AU - Farinacci F AU - Ricci F AU - Listorti C AU - Cirocchi R AU - Boselli C AU - Noya G AU - Parisi A FA - Trastulli, Stefano FA - Desiderio, Jacopo FA - Farinacci, Federico FA - Ricci, Francesco FA - Listorti, Chiara FA - Cirocchi, Roberto FA - Boselli, Carlo FA - Noya, Giuseppe FA - Parisi, Amilcare IN - Trastulli, Stefano. Department of Digestive Surgery and Liver Unit, S. Maria Hospital, Terni, Italy. stefano.trastulli@hotmail.it TI - Robotic right colectomy for cancer with intracorporeal anastomosis: short-term outcomes from a single institution. SO - International Journal of Colorectal Disease. 28(6):807-14, 2013 Jun AS - Int J Colorectal Dis. 28(6):807-14, 2013 Jun NJ - International journal of colorectal disease PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - itf, 8607899 IO - Int J Colorectal Dis SB - Index Medicus CP - Germany MH - Aged MH - Aged, 80 and over MH - Anastomosis, Surgical MH - *Colectomy/mt [Methods] MH - Colon/pa [Pathology] MH - *Colon/su [Surgery] MH - *Colonic Neoplasms/su [Surgery] MH - Colostomy MH - Female MH - Humans MH - Ileostomy MH - Male MH - Middle Aged MH - Operative Time MH - *Robotics MH - Surgical Stapling MH - Treatment Outcome AB - PURPOSE: Laparoscopic surgery for colon cancer has widely accepted as safe and effective. However, few studies report outcomes on robotic right colon resection with confectioning of the intracorporeal ileocolic anastomosis. This study aims to evaluate the feasibility and safety of robotic right colon resection with intracorporeal ileocolic anastomosis (RRCIA) in patients with cancer. AB - METHODS: Data of consecutive series of 20 patients undergoing RRCIA between June 2011 and May 2012 at our institution were prospectively collected in order to evaluate surgical and oncological short-term outcomes. AB - RESULTS: Seven males and 13 females were operated of RRCIA during the study period. Mean age is 66.7 years. The mean overall operative time was 327.5 min (255-485), and the robot time was 286 min (range 225-440 min). No conversion to open or laparoscopy occurred. The mean specimen length was 32.7 cm (range 26-44 cm), and the mean number of harvested lymph nodes was 17.6 (range 14-21). During the 30 postoperative days, only one complication occurred, consisting in an infection of surgical specimen extraction wound. AB - CONCLUSION: The RRCIA is a feasible and safe for patients with right colon cancer, also in terms of intraoperative oncological outcomes. ES - 1432-1262 IL - 0179-1958 DO - https://dx.doi.org/10.1007/s00384-012-1604-6 PT - Journal Article PT - Observational Study ID - 23114476 [pubmed] ID - 10.1007/s00384-012-1604-6 [doi] PP - ppublish PH - 2012/10/17 [accepted] LG - English EP - 20121101 DP - 2013 Jun DC - 20130527 EZ - 2012/11/02 06:00 DA - 2013/12/19 06:00 DT - 2012/11/02 06:00 YR - 2013 ED - 20131218 RD - 20130527 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23114476 <277. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23468046 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Vizza E AU - Corrado G AU - Mancini E AU - Baiocco E AU - Patrizi L AU - Fabrizi L AU - Colantonio L AU - Cimino M AU - Sindico S AU - Forastiere E FA - Vizza, Enrico FA - Corrado, Giacomo FA - Mancini, Emanuela FA - Baiocco, Ermelinda FA - Patrizi, Lodovico FA - Fabrizi, Luana FA - Colantonio, Luca FA - Cimino, Monica FA - Sindico, Stefano FA - Forastiere, Ester IN - Vizza, Enrico. Gynecologic Oncologic Unit, Department of Oncological Surgery, "Regina Elena" National Cancer Institute, Rome, Italy. TI - Robotic single-site hysterectomy in low risk endometrial cancer: a pilot study. SO - Annals of Surgical Oncology. 20(8):2759-64, 2013 Aug AS - Ann Surg Oncol. 20(8):2759-64, 2013 Aug NJ - Annals of surgical oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - b9r, 9420840 IO - Ann. Surg. Oncol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - Blood Loss, Surgical MH - *Endometrial Neoplasms/su [Surgery] MH - Female MH - Humans MH - Hysterectomy/ae [Adverse Effects] MH - Hysterectomy/is [Instrumentation] MH - *Hysterectomy MH - Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/is [Instrumentation] MH - *Laparoscopy MH - Length of Stay MH - Middle Aged MH - Operative Time MH - Pain, Postoperative/et [Etiology] MH - Pilot Projects MH - Robotics AB - BACKGROUND: To evaluate the feasibility and the safety of robotic single-site hysterectomy (RSSH) in low risk early endometrial cancer. AB - METHODS: Patients with clinical low risk early endometrial cancer were enrolled onto a prospective cohort trial. All surgical procedures were performed through a single 2-2.5 cm umbilical incision, with a multichannel system consisting of a five-lumen port providing access for two single-site instruments (da Vinci Si Surgical System, Intuitive Surgical, Sunnyvale, CA), the 8.5 mm 3D HD endoscope, a 5/10 mm accessory port, and an insufflation adaptor. AB - RESULTS: Between December 2011 and June 2012, a total of 17 patients were included in our pilot study. The median age of the patients was 64 years (range, 42-84 years), and median body mass index was 26.6 kg/m(2) (range, 18-52 kg/m(2)). One patient was excluded from the study as a result of pelvic metastasis during inspection of abdominal cavity, and another patient was converted to vaginal surgery as a result of problems of hypercapnia. The median docking time, console time, and total operative time was 8 min (range, 5-14 min), 48 min (range, 45-51 min), and 90 min (range, 70-147 min), respectively. The median blood loss was 75 mL (range, 50-150 mL). No laparoscopy/laparotomy conversion was registered. The median time to discharge was 2 days (range, 1-3 days). Neither intraoperative nor postoperative complications occurred. At a median of 7.5 months' follow-up, all patients were disease-free. AB - CONCLUSIONS: RSSH is technically feasible in patients affected by low risk early endometrial cancer. Additional studies with gynecologic oncologic cases should be performed to explore the possible benefits of RSSH. ES - 1534-4681 IL - 1068-9265 DO - https://dx.doi.org/10.1245/s10434-013-2922-9 PT - Clinical Trial PT - Journal Article ID - 23468046 [pubmed] ID - 10.1245/s10434-013-2922-9 [doi] PP - ppublish PH - 2012/08/28 [received] LG - English EP - 20130307 DP - 2013 Aug DC - 20130709 EZ - 2013/03/08 06:00 DA - 2013/12/18 06:00 DT - 2013/03/08 06:00 YR - 2013 ED - 20131213 RD - 20130709 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23468046 <278. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23571799 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Watanabe G AU - Matsumoto I AU - Kiuchi R FA - Watanabe, Go FA - Matsumoto, Isao FA - Kiuchi, Ryuta IN - Watanabe, Go. Department of General and Cardiothoracic Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan. watago6633@gmail.com TI - Novel sternum lifting technique for robotic internal thoracic artery graft harvesting. SO - Innovations: Technology & Techniques in Cardiothoracic & Vascular Surgery. 8(1):76-9, 2013 Jan-Feb AS - Innovations. 8(1):76-9, 2013 Jan-Feb NJ - Innovations (Philadelphia, Pa.) PI - Journal available in: Print PI - Citation processed from: Internet JC - 101257528 IO - Innovations (Phila) SB - Index Medicus CP - United States MH - Chi-Square Distribution MH - Equipment Design MH - Equipment Safety MH - Humans MH - Mammary Arteries/su [Surgery] MH - *Mammary Arteries/tr [Transplantation] MH - Minimally Invasive Surgical Procedures/mt [Methods] MH - Operative Time MH - Pneumothorax, Artificial/mt [Methods] MH - Reference Values MH - *Robotics/mt [Methods] MH - Statistics, Nonparametric MH - *Sternotomy/is [Instrumentation] MH - *Sternotomy/mt [Methods] MH - *Tissue and Organ Harvesting/mt [Methods] MH - Wound Healing/ph [Physiology] AB - Internal thoracic artery (ITA) harvesting using the robotic system usually requires artificially induced capnothorax to provide visualization and working space, but this procedure has the disadvantage of deteriorating the hemodynamics. We developed an electrical sternum lifting system (ESLS) for robotic ITA harvesting, which is robust and can be finely adjusted, capable of lifting the sternum for a maximum of 5 to 10 cm. Using a mechanical sternum lifting device significantly (P < 0.01) shortened the time of ITA harvesting from a mean +/- SD of 55.5 +/- 24.1 minutes to 33.0 +/- 15.7 minutes. No patient using the ESLS required induced capnothorax. Our novel ESLS provides a good operative field of view and allows ITA harvesting without inducing capnothorax. ES - 1559-0879 IL - 1556-9845 DI - 01243895-201301000-00014 DO - https://dx.doi.org/10.1097/IMI.0b013e31828d90ee PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 23571799 [pubmed] ID - 10.1097/IMI.0b013e31828d90ee [doi] ID - 01243895-201301000-00014 [pii] PP - ppublish LG - English DP - 2013 Jan-Feb DC - 20130410 EZ - 2013/04/11 06:00 DA - 2013/11/15 06:00 DT - 2013/04/11 06:00 YR - 2013 ED - 20131114 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23571799 <279. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23982574 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Vaccaro CM AU - Crisp CC AU - Fellner AN AU - Jackson C AU - Kleeman SD AU - Pavelka J FA - Vaccaro, Christine M FA - Crisp, Catrina C FA - Fellner, Angela N FA - Jackson, Christopher FA - Kleeman, Steven D FA - Pavelka, James IN - Vaccaro, Christine M. Division of Urogynecology and Pelvic Reconstructive Surgery, Madigan Healthcare System, Tacoma, WA, USA. vaccaro.christine@gmail.com TI - Robotic virtual reality simulation plus standard robotic orientation versus standard robotic orientation alone: a randomized controlled trial. SO - Female Pelvic Medicine & Reconstructive Surgery. 19(5):266-70, 2013 Sep-Oct AS - Female pelvic med. reconstr. surg.. 19(5):266-70, 2013 Sep-Oct NJ - Female pelvic medicine & reconstructive surgery PI - Journal available in: Print PI - Citation processed from: Print JC - 101528690 IO - Female Pelvic Med Reconstr Surg SB - Index Medicus CP - United States MH - Clinical Competence MH - *Computer Simulation MH - Female MH - General Surgery/ed [Education] MH - Gynecology/ed [Education] MH - Humans MH - *Internship and Residency/mt [Methods] MH - *Laparoscopy/ed [Education] MH - Learning Curve MH - Male MH - Obstetrics/ed [Education] MH - Operative Time MH - *Robotics/ed [Education] MH - Video Recording AB - OBJECTIVE: The objective of this study was to compare the effect of virtual reality simulation training plus robotic orientation versus robotic orientation alone on performance of surgical tasks using an inanimate model. AB - METHODS: Surgical resident physicians were enrolled in this assessor-blinded randomized controlled trial. Residents were randomized to receive either (1) robotic virtual reality simulation training plus standard robotic orientation or (2) standard robotic orientation alone. Performance of surgical tasks was assessed at baseline and after the intervention. Nine of 33 modules from the da Vinci Skills Simulator were chosen. Experts in robotic surgery evaluated each resident's videotaped performance of the inanimate model using the Global Rating Scale (GRS) and Objective Structured Assessment of Technical Skills-modified for robotic-assisted surgery (rOSATS). AB - RESULTS: Nine resident physicians were enrolled in the simulation group and 9 in the control group. As a whole, participants improved their total time, time to incision, and suture time from baseline to repeat testing on the inanimate model (P = 0.001, 0.003, <0.001, respectively). Both groups improved their GRS and rOSATS scores significantly (both P < 0.001); however, the GRS overall pass rate was higher in the simulation group compared with the control group (89% vs 44%, P = 0.066). AB - CONCLUSIONS: Standard robotic orientation and/or robotic virtual reality simulation improve surgical skills on an inanimate model, although this may be a function of the initial "practice" on the inanimate model and repeat testing of a known task. However, robotic virtual reality simulation training increases GRS pass rates consistent with improved robotic technical skills learned in a virtual reality environment. IS - 2151-8378 IL - 2151-8378 DI - 01436319-201309000-00004 DO - https://dx.doi.org/10.1097/SPV.0b013e3182a09101 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 23982574 [pubmed] ID - 10.1097/SPV.0b013e3182a09101 [doi] ID - 01436319-201309000-00004 [pii] PP - ppublish LG - English DP - 2013 Sep-Oct DC - 20130828 EZ - 2013/08/29 06:00 DA - 2013/11/08 06:00 DT - 2013/08/29 06:00 YR - 2013 ED - 20131107 RD - 20130828 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23982574 <280. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23377862 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Clarke H AU - Kirkham KR AU - Orser BA AU - Katznelson R AU - Mitsakakis N AU - Ko R AU - Snyman A AU - Ma M AU - Katz J FA - Clarke, Hance FA - Kirkham, Kyle R FA - Orser, Beverley A FA - Katznelson, Rita FA - Mitsakakis, Nicholas FA - Ko, Raynauld FA - Snyman, Adam FA - Ma, Martin FA - Katz, Joel IN - Clarke, Hance. Department of Anesthesia and Pain Management, Toronto General Hospital, 200 Elizabeth Street, Eaton North 3 EB 317, Acute Pain Research Unit, Toronto, ON, M5G 2C4, Canada. hance.clarke@utoronto.ca TI - Gabapentin reduces preoperative anxiety and pain catastrophizing in highly anxious patients prior to major surgery: a blinded randomized placebo-controlled trial. SO - Canadian Journal of Anaesthesia. 60(5):432-43, 2013 May AS - Can J Anaesth. 60(5):432-43, 2013 May NJ - Canadian journal of anaesthesia = Journal canadien d'anesthesie PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - c8l, 8701709 IO - Can J Anaesth SB - Index Medicus CP - United States MH - Adult MH - *Amines/tu [Therapeutic Use] MH - Analysis of Variance MH - *Anti-Anxiety Agents/tu [Therapeutic Use] MH - *Anxiety/dt [Drug Therapy] MH - Anxiety/et [Etiology] MH - *Catastrophization/dt [Drug Therapy] MH - *Cyclohexanecarboxylic Acids/tu [Therapeutic Use] MH - Double-Blind Method MH - Female MH - Hospitals, General MH - Humans MH - Middle Aged MH - Pain/et [Etiology] MH - Pain/pc [Prevention & Control] MH - Pain/px [Psychology] MH - Preoperative Care/mt [Methods] MH - Treatment Outcome MH - *gamma-Aminobutyric Acid/tu [Therapeutic Use] AB - INTRODUCTION: Gabapentin is increasingly being used for the treatment of postoperative pain and a variety of psychiatric diseases, including chronic anxiety disorders. Trials have reported mixed results when gabapentin has been administered for the treatment of preoperative anxiety. We tested the hypothesis that gabapentin 1,200 mg vs placebo would reduce preoperative anxiety in patients who exhibit moderate to high preoperative anxiety. AB - METHODS: A blinded randomized controlled trial was conducted from September 2009 to June 2011 at the Toronto General Hospital. Following ethics approval and informed consent, 50 female patients with a 0-10 numeric rating scale (NRS) anxiety score of greater than or equal to 5/10 consented to receive either gabapentin 1,200 mg (n = 25) or placebo (n = 25) prior to surgery. Randomization was computer generated, and the Investigational Pharmacy was responsible for the blinding and dispensing of medication. All patients and care providers, including physicians, nurses, and study personnel, were blinded to group allocation. Before administering the study medication, baseline anxiety levels were measured using a NRS, the Spielberger State-Trait Anxiety Inventories, the Pain Catastrophizing Scale, and the Pain Anxiety Symptoms Scale-20. Baseline pain intensity (0-10 NRS) and level of sedation (0-10 NRS and Richmond Agitation-Sedation Scale [RASS]) were also measured. Two hours after the administration of gabapentin or placebo (prior to surgery), patients again rated their anxiety, pain, and sedation levels using the same measurement tools as at baseline. The main outcome was a reduction in preoperative anxiety. AB - RESULTS: Forty-four patients (22 treated with gabapentin 1,200 mg and 22 treated with placebo) were included in the analysis of the primary outcome. Analysis of covariance in which pre-drug NRS anxiety scores were used as the covariate showed that post-drug preoperative NRS anxiety (Effect size, 1.44; confidence interval [CI] 0.19 to 2.70) and pain catastrophizing (Effect size, 0.43; CI 0.12 to 0.74) scores were significantly lower in the gabapentin group than in the placebo control group, respectively. Post-drug sedation (Effect size, -3.02; CI -4.28 to -1.77) and RASS (Effect size, 0.41; CI 0.12 to 0.71) scores were significantly higher in the gabapentin group than in the placebo group, respectively. AB - CONCLUSIONS: Administration of gabapentin 1,200 mg prior to surgery reduces preoperative NRS anxiety scores and pain catastrophizing scores and increases sedation prior to entering the operating room. These results suggest that gabapentin 1,200 mg may be a treatment option for patients who exhibit high levels of preoperative anxiety and pain catastrophizing; however, the sedative properties of the medication and the possibility of delayed postoperative discharge in the elective ambulatory population need to be considered. RN - 0 (Amines) RN - 0 (Anti-Anxiety Agents) RN - 0 (Cyclohexanecarboxylic Acids) RN - 56-12-2 (gamma-Aminobutyric Acid) RN - 6CW7F3G59X (gabapentin) ES - 1496-8975 IL - 0832-610X DO - https://dx.doi.org/10.1007/s12630-013-9890-1 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 23377862 [pubmed] ID - 10.1007/s12630-013-9890-1 [doi] PP - ppublish PH - 2012/09/25 [received] PH - 2013/01/14 [accepted] GI - Organization: *Canadian Institutes of Health Research* Country: Canada LG - English EP - 20130202 DP - 2013 May DC - 20130418 EZ - 2013/02/05 06:00 DA - 2013/10/31 06:00 DT - 2013/02/05 06:00 YR - 2013 ED - 20131030 RD - 20130418 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23377862 <281. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23685743 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Truong QA AU - Hayden D AU - Woodard PK AU - Kirby R AU - Chou ET AU - Nagurney JT AU - Wiviott SD AU - Fleg JL AU - Schoenfeld DA AU - Udelson JE AU - Hoffmann U FA - Truong, Quynh A FA - Hayden, Douglas FA - Woodard, Pamela K FA - Kirby, Ruth FA - Chou, Eric T FA - Nagurney, John T FA - Wiviott, Stephen D FA - Fleg, Jerome L FA - Schoenfeld, David A FA - Udelson, James E FA - Hoffmann, Udo IN - Truong, Quynh A. Cardiac MR PET CT Program, Division of Cardiology and Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 165 Cambridge St, Ste 400, Boston, MA 02114, USA. qtruong@partners.org TI - Sex differences in the effectiveness of early coronary computed tomographic angiography compared with standard emergency department evaluation for acute chest pain: the rule-out myocardial infarction with Computer-Assisted Tomography (ROMICAT)-II Trial. SO - Circulation. 127(25):2494-502, 2013 Jun 25 AS - Circulation. 127(25):2494-502, 2013 Jun 25 NJ - Circulation PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - daw, 0147763 IO - Circulation PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753028 OI - Source: NLM. NIHMS494091 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - *Acute Coronary Syndrome/di [Diagnosis] MH - Acute Coronary Syndrome/dg [Diagnostic Imaging] MH - Acute Coronary Syndrome/ep [Epidemiology] MH - Acute Disease MH - Adult MH - Aged MH - *Chest Pain/di [Diagnosis] MH - Chest Pain/dg [Diagnostic Imaging] MH - Chest Pain/ep [Epidemiology] MH - *Coronary Angiography MH - Diagnosis, Differential MH - *Diagnostic Tests, Routine MH - *Emergency Service, Hospital MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Myocardial Infarction/di [Diagnosis] MH - Myocardial Infarction/dg [Diagnostic Imaging] MH - Myocardial Infarction/ep [Epidemiology] MH - Prevalence MH - Severity of Illness Index MH - *Tomography, X-Ray Computed KW - acute coronary syndrome; chest pain; emergency service, hospital; sex; tomography, x-ray computed AB - BACKGROUND: We evaluate sex-based differences in the effectiveness of early cardiac computed tomographic angiography (CCTA) and standard emergency department (ED) evaluation in patients with acute chest pain. AB - METHODS AND RESULTS: In the Rule-Out Myocardial Infarction With Computer-Assisted Tomography (ROMICAT)-II multicenter, controlled trial, we randomized 1000 patients (47% women) 40 to 74 years of age with symptoms suggestive of acute coronary syndrome to an early CCTA or standard ED evaluation. In this prespecified analysis, women in the CCTA arm had a greater reduction in length of stay, lower hospital admission rates, and lesser increased cumulative radiation dose than men in a comparison of ED strategies (P for interaction <0.02). Although women had lower acute coronary syndrome rates than men (3% versus 12%; P<0.0001), sex differences in length of stay persisted after adjustment for baseline differences, including acute coronary syndrome rate (P for interaction <0.03). Length of stay was similar between sexes with normal CCTA findings (P=0.11). There was no missed acute coronary syndrome for either sex. No difference was observed in major adverse cardiac events between sexes and ED strategies (P for interaction =0.39). Women had more normal CCTA examinations than men (58% versus 37%; P<0.0001), less obstructive coronary disease by CCTA (5% versus 17%; P=0.0001), but similar normalcy rates for functional testing (P=0.65). Men in the CCTA arm had the highest rate of invasive coronary angiography (18%), whereas women had comparable low 5% rates regardless of ED strategy. AB - CONCLUSIONS: This trial provides data supporting an early CCTA strategy as an attractive option in women presenting to the ED with symptoms suggestive of acute coronary syndrome. The findings may be explained by lower CAD prevalence and severity in women than men. AB - CLINICAL TRIAL REGISTRATION URL: http://www.clinicaltrials.gov. Unique identifier: NCT01084239. ES - 1524-4539 IL - 0009-7322 DI - CIRCULATIONAHA.113.001736 DO - https://dx.doi.org/10.1161/CIRCULATIONAHA.113.001736 PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't ID - 23685743 [pubmed] ID - CIRCULATIONAHA.113.001736 [pii] ID - 10.1161/CIRCULATIONAHA.113.001736 [doi] ID - PMC3753028 [pmc] ID - NIHMS494091 [mid] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01084239 SA - ClinicalTrials.gov/NCT01084239 SL - https://clinicaltrials.gov/search/term=NCT01084239 SL - https://clinicaltrials.gov/search/term=NCT01084239 GI - No: U01 HL092040 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30HL093896 Organization: (HL) *NHLBI NIH HHS* Country: United States No: U01 HL092022 Organization: (HL) *NHLBI NIH HHS* Country: United States No: U01HL092022 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K23HL098370 Organization: (HL) *NHLBI NIH HHS* Country: United States No: U01HL092040 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30 HL093806 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K24 HL113128 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K23 HL098370 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English EP - 20130517 DP - 2013 Jun 25 DC - 20130626 EZ - 2013/05/21 06:00 DA - 2013/09/26 06:00 DT - 2013/05/21 06:00 YR - 2013 ED - 20130925 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23685743 <282. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23030798 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sammon JD AU - Sharma P AU - Trinh QD AU - Ghani KR AU - Sukumar S AU - Menon M FA - Sammon, Jesse D FA - Sharma, Pranav FA - Trinh, Quoc-Dien FA - Ghani, Khurshid R FA - Sukumar, Shyam FA - Menon, Mani IN - Sammon, Jesse D. Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI 48202, USA. jsammon79@gmail.com TI - Predictors of immediate continence following robot-assisted radical prostatectomy. CM - Comment in: J Endourol. 2013 Sep;27(9):1172; PMID: 23631752 CM - Comment in: J Urol. 2013 Oct;190(4):1249-50; PMID: 24029316 CM - Comment in: J Endourol. 2013 Sep;27(9):1172-3; PMID: 23931667 SO - Journal of Endourology. 27(4):442-6, 2013 Apr AS - J Endourol. 27(4):442-6, 2013 Apr NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Demography MH - Humans MH - Male MH - Middle Aged MH - Multivariate Analysis MH - *Prostatectomy/ae [Adverse Effects] MH - *Robotics MH - *Urinary Incontinence/et [Etiology] AB - INTRODUCTION: Few studies have examined the patient characteristics that lead to early continence after robot-assisted radical prostatectomy (RARP), and to date, there has been no investigation into the predictors of immediate continence. In the current study, we examine a large multisurgeon population of patients undergoing RARP to assess for predictors of this outcome. AB - PATIENTS AND METHODS: Between January 2008 and December 2010, 1270 patients who underwent RARP at our institution, with complete preoperative and follow-up data, were assessed for urinary function prospectively. Univariable and multivariable logistic regressions were used to assess for predictors of zero pad usage after RARP. Patient and operative characteristics examined include age, body-mass index, prostate-specific antigen, adjusted Charlson comorbidity index (CCI), Gleason sum, international prostate symptom score, clinical stage, nerve sparing, bladder neck reconstruction, posterior anastomotic reconstruction, surgeon volume, and percutaneous suprapubic tube (PST) bladder drainage. AB - RESULTS: Overall, 17.3% of patients (n=219) never required a pad after catheter removal. Characteristics associated with never requiring a pad are age, preoperative Gleason sum, CCI, nerve sparing, prostate weight, surgeon volume, and PST bladder drainage. Independent predictors of never requiring a pad after catheter removal included nerve-sparing (B/L standard as referent) wide dissection [OR: 0.96 (95% CI: 0.49, 1.88)], unilateral inter-/intrafascial [OR: 1.20 (0.70, 2.06)], bilateral inter-/intrafascial [OR: 1.97 (1.36, 2.86)], and PST drainage [OR: 2.53 (1.56, 4.11)]. AB - CONCLUSION: In a study reflective of broad RARP practice at our institution, 17.3% of patients were entirely pad free after RARP. The type of nerve sparing performed and placement of a PST for bladder drainage postoperatively were found to be independently predictive of never requiring a pad after RARP. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2012.0312 PT - Clinical Trial PT - Journal Article ID - 23030798 [pubmed] ID - 10.1089/end.2012.0312 [doi] PP - ppublish LG - English EP - 20121205 DP - 2013 Apr DC - 20130409 EZ - 2012/10/04 06:00 DA - 2013/09/26 06:00 DT - 2012/10/04 06:00 YR - 2013 ED - 20130925 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23030798 <283. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23685743 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Truong QA AU - Hayden D AU - Woodard PK AU - Kirby R AU - Chou ET AU - Nagurney JT AU - Wiviott SD AU - Fleg JL AU - Schoenfeld DA AU - Udelson JE AU - Hoffmann U FA - Truong, Quynh A FA - Hayden, Douglas FA - Woodard, Pamela K FA - Kirby, Ruth FA - Chou, Eric T FA - Nagurney, John T FA - Wiviott, Stephen D FA - Fleg, Jerome L FA - Schoenfeld, David A FA - Udelson, James E FA - Hoffmann, Udo IN - Truong, Quynh A. Cardiac MR PET CT Program, Division of Cardiology and Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 165 Cambridge St, Ste 400, Boston, MA 02114, USA. qtruong@partners.org TI - Sex differences in the effectiveness of early coronary computed tomographic angiography compared with standard emergency department evaluation for acute chest pain: the rule-out myocardial infarction with Computer-Assisted Tomography (ROMICAT)-II Trial. SO - Circulation. 127(25):2494-502, 2013 Jun 25 AS - Circulation. 127(25):2494-502, 2013 Jun 25 NJ - Circulation PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - daw, 0147763 IO - Circulation PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753028 OI - Source: NLM. NIHMS494091 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - *Acute Coronary Syndrome/di [Diagnosis] MH - Acute Coronary Syndrome/dg [Diagnostic Imaging] MH - Acute Coronary Syndrome/ep [Epidemiology] MH - Acute Disease MH - Adult MH - Aged MH - *Chest Pain/di [Diagnosis] MH - Chest Pain/dg [Diagnostic Imaging] MH - Chest Pain/ep [Epidemiology] MH - *Coronary Angiography MH - Diagnosis, Differential MH - *Diagnostic Tests, Routine MH - *Emergency Service, Hospital MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Myocardial Infarction/di [Diagnosis] MH - Myocardial Infarction/dg [Diagnostic Imaging] MH - Myocardial Infarction/ep [Epidemiology] MH - Prevalence MH - Severity of Illness Index MH - *Tomography, X-Ray Computed KW - acute coronary syndrome; chest pain; emergency service, hospital; sex; tomography, x-ray computed AB - BACKGROUND: We evaluate sex-based differences in the effectiveness of early cardiac computed tomographic angiography (CCTA) and standard emergency department (ED) evaluation in patients with acute chest pain. AB - METHODS AND RESULTS: In the Rule-Out Myocardial Infarction With Computer-Assisted Tomography (ROMICAT)-II multicenter, controlled trial, we randomized 1000 patients (47% women) 40 to 74 years of age with symptoms suggestive of acute coronary syndrome to an early CCTA or standard ED evaluation. In this prespecified analysis, women in the CCTA arm had a greater reduction in length of stay, lower hospital admission rates, and lesser increased cumulative radiation dose than men in a comparison of ED strategies (P for interaction <0.02). Although women had lower acute coronary syndrome rates than men (3% versus 12%; P<0.0001), sex differences in length of stay persisted after adjustment for baseline differences, including acute coronary syndrome rate (P for interaction <0.03). Length of stay was similar between sexes with normal CCTA findings (P=0.11). There was no missed acute coronary syndrome for either sex. No difference was observed in major adverse cardiac events between sexes and ED strategies (P for interaction =0.39). Women had more normal CCTA examinations than men (58% versus 37%; P<0.0001), less obstructive coronary disease by CCTA (5% versus 17%; P=0.0001), but similar normalcy rates for functional testing (P=0.65). Men in the CCTA arm had the highest rate of invasive coronary angiography (18%), whereas women had comparable low 5% rates regardless of ED strategy. AB - CONCLUSIONS: This trial provides data supporting an early CCTA strategy as an attractive option in women presenting to the ED with symptoms suggestive of acute coronary syndrome. The findings may be explained by lower CAD prevalence and severity in women than men. AB - CLINICAL TRIAL REGISTRATION URL: http://www.clinicaltrials.gov. Unique identifier: NCT01084239. ES - 1524-4539 IL - 0009-7322 DI - CIRCULATIONAHA.113.001736 DO - https://dx.doi.org/10.1161/CIRCULATIONAHA.113.001736 PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't ID - 23685743 [pubmed] ID - CIRCULATIONAHA.113.001736 [pii] ID - 10.1161/CIRCULATIONAHA.113.001736 [doi] ID - PMC3753028 [pmc] ID - NIHMS494091 [mid] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01084239 SL - https://clinicaltrials.gov/search/term=NCT01084239 GI - No: U01 HL092040 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30HL093896 Organization: (HL) *NHLBI NIH HHS* Country: United States No: U01 HL092022 Organization: (HL) *NHLBI NIH HHS* Country: United States No: U01HL092022 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K23HL098370 Organization: (HL) *NHLBI NIH HHS* Country: United States No: U01HL092040 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30 HL093806 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K24 HL113128 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K23 HL098370 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English EP - 20130517 DP - 2013 Jun 25 DC - 20130626 EZ - 2013/05/21 06:00 DA - 2013/09/26 06:00 DT - 2013/05/21 06:00 YR - 2013 ED - 20130925 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=23685743 <284. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23735669 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Benizri EI AU - Renaud M AU - Reibel N AU - Germain A AU - Ziegler O AU - Zarnegar R AU - Ayav A AU - Bresler L AU - Brunaud L FA - Benizri, Emmanuel I FA - Renaud, Myriam FA - Reibel, Nicolas FA - Germain, Adeline FA - Ziegler, Olivier FA - Zarnegar, Rasa FA - Ayav, Ahmet FA - Bresler, Laurent FA - Brunaud, Laurent IN - Benizri, Emmanuel I. Multidisciplinary Unit for Obesity Surgery UMCO, Centre Hospitalier Universitaire de Nancy, 54511 Vandoeuvre, France. benizri.e@chu-nice.fr TI - Perioperative outcomes after totally robotic gastric bypass: a prospective nonrandomized controlled study. SO - American Journal of Surgery. 206(2):145-51, 2013 Aug AS - Am J Surg. 206(2):145-51, 2013 Aug NJ - American journal of surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 3z4, 0370473 IO - Am. J. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Conversion to Open Surgery/sn [Statistics & Numerical Data] MH - Female MH - France/ep [Epidemiology] MH - *Gastric Bypass/ae [Adverse Effects] MH - *Gastric Bypass/is [Instrumentation] MH - Gastric Bypass/mt [Methods] MH - Humans MH - Incidence MH - Laparotomy/sn [Statistics & Numerical Data] MH - *Length of Stay/sn [Statistics & Numerical Data] MH - Male MH - Middle Aged MH - Multivariate Analysis MH - *Obesity, Morbid/su [Surgery] MH - Odds Ratio MH - Operative Time MH - *Postoperative Complications/ep [Epidemiology] MH - *Postoperative Complications/et [Etiology] MH - Prospective Studies MH - Risk Factors MH - *Robotics MH - Time Factors MH - Treatment Outcome KW - Bariatrics; Gastric bypass; Morbidity obesity; Robotics AB - BACKGROUND: Perioperative short-term outcomes could be improved after totally robotic Roux-en-Y gastric bypass (TR-RYGBP) compared with conventional laparoscopic gastric bypass. AB - METHODS: This is a nonrandomized controlled prospective study (N = 200) to evaluate perioperative short-term outcomes. The primary endpoint was to investigate risk factors for 30-day surgical complications. AB - RESULTS: Mean total operative time was shorter in patients who underwent TR-RYGBP (130 vs 147 minutes; P < .0001). However, postoperative surgical complications rate (13% vs 1%; P = .001), and mean overall hospital stay (9.3 vs 6.7 days; P < .0001) were higher after TR-RYGBP. By multivariate analysis, robotic surgery (hazard ratio [HR] = 15.1; 95% confidence interval [CI], 2.8 to 280; P = .01), and conversion to laparotomy (HR = 18.8; 95% CI, 1.7 to 250.8; P = .014) were independent risk factors for 30-day surgical complications. AB - CONCLUSIONS: Although robotic gastric bypass reduces mean operative time, TR-RYGBP is associated with an increased postoperative surgical complications rate and longer hospitalization. AB - Copyright © 2013 Elsevier Inc. All rights reserved. ES - 1879-1883 IL - 0002-9610 DI - S0002-9610(13)00220-1 DO - https://dx.doi.org/10.1016/j.amjsurg.2012.07.049 PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article ID - 23735669 [pubmed] ID - S0002-9610(13)00220-1 [pii] ID - 10.1016/j.amjsurg.2012.07.049 [doi] PP - ppublish PH - 2012/05/30 [received] PH - 2012/07/05 [revised] PH - 2012/07/17 [accepted] LG - English EP - 20130602 DP - 2013 Aug DC - 20130722 EZ - 2013/06/06 06:00 DA - 2013/09/24 06:00 DT - 2013/06/06 06:00 YR - 2013 ED - 20130923 RD - 20130722 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23735669 <285. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23806395 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Massoud W AU - Thanigasalam R AU - El Hajj A AU - Girard F AU - Theveniaud PE AU - Chatellier G AU - Baumert H FA - Massoud, Walid FA - Thanigasalam, Ruban FA - El Hajj, Albert FA - Girard, Frederic FA - Theveniaud, Pierre Etienne FA - Chatellier, Gilles FA - Baumert, Herve IN - Massoud, Walid. Department of Urology, Hopital Saint Joseph, Paris, France. TI - Does the use of a barbed polyglyconate absorbable suture have an impact on urethral anastomosis time, urethral stenosis rates, and cost effectiveness during robot-assisted radical prostatectomy?. SO - Urology. 82(1):90-4, 2013 Jul AS - Urology. 82(1):90-4, 2013 Jul NJ - Urology PI - Journal available in: Print PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Aged MH - Anastomosis, Surgical/ae [Adverse Effects] MH - Anastomosis, Surgical/is [Instrumentation] MH - Cost-Benefit Analysis MH - Equipment Design MH - Humans MH - Male MH - Middle Aged MH - Operative Time MH - Polymers MH - Prostatectomy/ae [Adverse Effects] MH - Prostatectomy/ec [Economics] MH - Robotics MH - *Suture Techniques/is [Instrumentation] MH - Sutures/ae [Adverse Effects] MH - Sutures/ec [Economics] MH - *Sutures MH - *Urethra/su [Surgery] MH - Urethral Stricture/et [Etiology] MH - *Urinary Bladder/su [Surgery] MH - Urinary Incontinence/et [Etiology] MH - *Veins/su [Surgery] MH - Wound Healing AB - OBJECTIVE: To evaluate the use of a single needle driver with the V-Loc (Covidien, Dublin, Ireland) running suture and compare this with the use of 2 needle drivers with polyglactin interrupted sutures (IS) in dividing the dorsal venous complex (DVC) and forming the urethrovesical anastomosis (UVA) during robot-assisted radical prostatectomy (RARP). AB - MATERIALS AND METHODS: A prospective cohort study was performed to compare V-Loc (n = 40) with polyglactin (n = 40) sutures. Division of the dorsal venous complex and formation of the UVA during robot-assisted radical prostatectomy using V-Loc or polyglactin sutures were studied. Preoperative, intraoperative, and postoperative parameters were measured. AB - RESULTS: V-Loc sutures were associated with a statistically significant reduction in mean dorsal vein suture time (3.15 minutes V-Loc vs 3.75 minutes IS, P = .02) and UVA anastomosis time (8.5 minutes V-Loc vs 11.5 minutes IS, P = .001). No significant difference was noted between operative time (121 minutes V-Loc vs 130 minutes IS, P = .199), delayed healing rates (5% V-Loc vs 7.5% IS, P = .238), continence rate at 12 months (97.5% V-Loc vs 95% IS, P = .368), and urethral stenosis rates (2.5% V-Loc vs 2.5% IS, P = .347) in both groups. AB - CONCLUSION: The use of a V-Loc running suture with a single needle driver is a feasible, reproducible, and economic technique with no significant difference in continence rates and urethral stenosis rates, compared with the use of a traditional interrupted suture. AB - Copyright © 2013 Elsevier Inc. All rights reserved. RN - 0 (Polymers) RN - 75734-93-9 (polyglyconate) ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(13)00163-5 DO - https://dx.doi.org/10.1016/j.urology.2013.02.002 PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article ID - 23806395 [pubmed] ID - S0090-4295(13)00163-5 [pii] ID - 10.1016/j.urology.2013.02.002 [doi] PP - ppublish PH - 2012/08/05 [received] PH - 2013/01/18 [revised] PH - 2013/02/01 [accepted] LG - English DP - 2013 Jul DC - 20130628 EZ - 2013/06/29 06:00 DA - 2013/09/17 06:00 DT - 2013/06/29 06:00 YR - 2013 ED - 20130916 RD - 20130628 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23806395 <286. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22967208 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Fuller A AU - Vanderhaeghe L AU - Nott L AU - Martin PR AU - Pautler SE FA - Fuller, Andrew FA - Vanderhaeghe, Leanne FA - Nott, Linda FA - Martin, Paul R FA - Pautler, Stephen E IN - Fuller, Andrew. Division of Urology, Department of Surgery, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, Canada. TI - Intravesical ropivacaine as a novel means of analgesia post-robot-assisted radical prostatectomy: a randomized, double-blind, placebo-controlled trial. SO - Journal of Endourology. 27(3):313-7, 2013 Mar AS - J Endourol. 27(3):313-7, 2013 Mar NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Acetaminophen/tu [Therapeutic Use] MH - Administration, Intravesical MH - Aged MH - *Amides/ad [Administration & Dosage] MH - *Amides/tu [Therapeutic Use] MH - *Analgesia MH - *Anesthetics, Local/ad [Administration & Dosage] MH - *Anesthetics, Local/tu [Therapeutic Use] MH - Double-Blind Method MH - Humans MH - Ketorolac/tu [Therapeutic Use] MH - Male MH - Middle Aged MH - Pain Measurement MH - Pain, Postoperative/dt [Drug Therapy] MH - Placebos MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/pa [Pathology] MH - Prostatic Neoplasms/su [Surgery] MH - *Robotics AB - PURPOSE: This study evaluates the safety and efficacy of intravesical ropivacaine as part of a mulitimodal approach to the provision of analgesia after robot-assisted radical prostatectomy (RARP). AB - PATIENTS AND METHODS: In this double-blind, placebo-controlled trial, 40 patients who were scheduled to undergo RARP for treatment of localized prostate cancer by a single surgeon (SP) were randomized 1:1 to receive either alkalinized intravesical ropivacaine or placebo (0.9% sodium chloride) at the completion of the vesicourethral anastomosis. A standardized general anesthetic was administered in each case. The primary outcome was a reduction in postoperative pain as assessed by a visual analogue scale (VAS). The need for alternate analgesic agents was recorded. Adverse events related to the administration of intravesical ropivacaine were documented prospectively. AB - RESULTS: No serious adverse events related to the administration of intravesical ropivacaine were identified. In the ropivacaine group, there was a significant reduction in the cumulative needed dose of ketoralac relative to placebo at 6 hours postoperatively. There was no statistically significant difference between the groups with regard to pain scores or narcotic use at any time point. AB - CONCLUSIONS: Intravesical administration of ropivacaine may be used safely in the context of RARP and is associated with a significant, albeit modest reduction in the need for supplementary analgesic agents, but did not result in a decrease in postoperative pain scores. RN - 0 (Amides) RN - 0 (Anesthetics, Local) RN - 0 (Placebos) RN - 362O9ITL9D (Acetaminophen) RN - 7IO5LYA57N (ropivacaine) RN - YZI5105V0L (Ketorolac) ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2012.0191 PT - Journal Article PT - Randomized Controlled Trial ID - 22967208 [pubmed] ID - 10.1089/end.2012.0191 [doi] PP - ppublish LG - English EP - 20121127 DP - 2013 Mar DC - 20130308 EZ - 2012/09/13 06:00 DA - 2013/09/13 06:00 DT - 2012/09/13 06:00 YR - 2013 ED - 20130912 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=22967208 <287. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22967179 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Jain S AU - Yates JK AU - Munver R FA - Jain, Samay FA - Yates, Jennifer K FA - Munver, Ravi IN - Jain, Samay. Department of Urology, Hackensack University Medical Center, Hackensack, NJ 07601, USA. drjain06@yahoo.com TI - Robot-assisted laparoscopic partial nephrectomy for recurrent renal-cell carcinoma in patients previously treated with nephron-sparing surgery. SO - Journal of Endourology. 27(3):309-12, 2013 Mar AS - J Endourol. 27(3):309-12, 2013 Mar NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - *Carcinoma, Renal Cell/su [Surgery] MH - Demography MH - Humans MH - Kidney/su [Surgery] MH - *Kidney Neoplasms/su [Surgery] MH - *Laparoscopy MH - Male MH - Middle Aged MH - *Neoplasm Recurrence, Local/su [Surgery] MH - *Nephrectomy/mt [Methods] MH - *Organ Sparing Treatments/mt [Methods] MH - Perioperative Care MH - *Robotics AB - BACKGROUND AND PURPOSE: With the advent of robotics, it may be more feasible to offer minimally invasive nerve-sparing surgery (NSS), in the form of partial nephrectomy (PN), for patients with metachronous recurrence in the ipsilateral kidney after previous NSS. We studied the outcomes of patients undergoing robot-assisted laparoscopic partial nephrectomy (RAPN) after previous ipsilateral open or laparoscopic NSS for renal-cell carcinoma. AB - METHODS: In this Institutional Review Board approved study, a prospectively maintained PN database was reviewed. Of 230 RAPNs performed between 2003 and 2011, five patients underwent RAPN after previous ipsilateral NSS. AB - RESULTS: The mean age was 64.2 years, and time between the first and second surgery was 27 months (range 9-60 mos). All patients were men and previously had open (n=4) or laparoscopic (n=1) NSS for clear-cell (n=2), papillary (n=2), and other (n=1) pathology. Average follow-up was 15.6 months (range 8-21 mos). There were no conversions to open surgery or radical nephrectomy. Total and selective arterial clamping were performed in two and two cases, respectively. One RAPN was performed off-clamp. Mean warm ischemia time was 14 minutes (range 0-32 min), and mean blood loss was 220 mL (range 50-400 mL). Average length of stay was 1.4 days (range 1-2 days) with no perioperative complications. The glomerular filtration rate decreased by a mean of 10%. There were no recurrences detected on cross-sectional imaging at the most recent follow-up. AB - CONCLUSION: RAPN after previous open or laparoscopic PN is safe and efficacious. It offers satisfactory intermediate functional and oncologic outcomes with minimal morbidity. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2012.0184 PT - Clinical Trial PT - Journal Article ID - 22967179 [pubmed] ID - 10.1089/end.2012.0184 [doi] PP - ppublish LG - English EP - 20121112 DP - 2013 Mar DC - 20130308 EZ - 2012/09/13 06:00 DA - 2013/09/13 06:00 DT - 2012/09/13 06:00 YR - 2013 ED - 20130912 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=22967179 <288. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22966792 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Clavijo R AU - Carmona O AU - De Andrade R AU - Garza R AU - Fernandez G AU - Sotelo R FA - Clavijo, Rafael FA - Carmona, Oswaldo FA - De Andrade, Robert FA - Garza, Roberto FA - Fernandez, Golena FA - Sotelo, Rene IN - Clavijo, Rafael. Robotic and Minimally Invasive Surgery Center, Instituto Medico La Floresta, Caracas, Venezuela. rafaclavijo@gmail.com TI - Robot-assisted intrafascial simple prostatectomy: novel technique. SO - Journal of Endourology. 27(3):328-32, 2013 Mar AS - J Endourol. 27(3):328-32, 2013 Mar NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Aged MH - Demography MH - Device Removal MH - *Fasciotomy MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Prostate/su [Surgery] MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - *Robotics MH - Seminal Vesicles/su [Surgery] MH - Sutures MH - Urethra/su [Surgery] MH - Urinary Catheterization MH - Urinary Incontinence/et [Etiology] AB - PURPOSE: We describe our initial experience with intrafascial robot-assisted simple prostatectomy (IF-RSP). Potential advantages include reduced blood loss, elimination of the need for postoperative bladder irrigation, and elimination of the risk of residual or future prostate cancer, without interrupting potency or continence. AB - PATIENTS AND METHODS: From June 2011 to March 2012, 10 patients with symptomatic prostatomegaly on transrectal ultrasonography (TRUS) (mean 81 g) underwent IF-RSP. Three patients had acute urinary retention. Demographic perioperative and outcome data were recorded up to 1 month follow-up. AB - RESULTS: Average age was 71.7 years (range 60-79 years), estimated blood loss was 375 mL (range 150-900 mL), operative time was 106 minutes (range 60-180 min), hospital stay was 1 day (range 0-3 days), and Foley catheter duration was 8.9 days (range 6-14 days). The drain was removed at a mean 2.8 days (range 0-8 days). Mean prostate volume on preoperative TRUS was 81 cc (range 47-153 cc). Mean specimen weight was 81 g (range 50-150 g). Improvement was noted in the International Prostate Symptom Score (preoperative vs postoperative 18.8 vs 1.7) and peak flow rate (12.4 vs 33.49 mL/min). Sexual Health Inventory for Men score ranged from 12 to 24. All patients were completely continent within 1 month postoperatively, and sexual function was preserved. One patient had urinary tract infection and one patient needed blood transfusion postoperatively. AB - CONCLUSIONS: IF-RSP appears to be a feasible procedure in large-volume prostatomegaly. The entire prostate tissue is removed without compromising continence and potency. Larger series and longer-term follow-up are needed to evaluate the proper place of this approach. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2012.0212 PT - Clinical Trial PT - Journal Article ID - 22966792 [pubmed] ID - 10.1089/end.2012.0212 [doi] PP - ppublish LG - English DP - 2013 Mar DC - 20130308 EZ - 2012/09/13 06:00 DA - 2013/09/13 06:00 DT - 2012/09/13 06:00 YR - 2013 ED - 20130912 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=22966792 <289. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23114883 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hole KH AU - Axcrona K AU - Lie AK AU - Vlatkovic L AU - Geier OM AU - Brennhovd B AU - Knutstad K AU - Olsen DR AU - Seierstad T FA - Hole, Knut Hakon FA - Axcrona, Karol FA - Lie, Agnes Kathrine FA - Vlatkovic, Ljiljana FA - Geier, Oliver Marcel FA - Brennhovd, Bjorn FA - Knutstad, Kjetil FA - Olsen, Dag Rune FA - Seierstad, Therese IN - Hole, Knut Hakon. Department of Radiology and Nuclear Medicine, Radiumhospitalet, Oslo University Hospital, Montebello, 0310 Oslo, Norway. TI - Routine pelvic MRI using phased-array coil for detection of extraprostatic tumour extension: accuracy and clinical significance. SO - European Radiology. 23(4):1158-66, 2013 Apr AS - Eur Radiol. 23(4):1158-66, 2013 Apr NJ - European radiology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - cl3, 9114774 IO - Eur Radiol PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599204 SB - Index Medicus CP - Germany MH - Adult MH - Aged MH - Equipment Design MH - Equipment Failure Analysis MH - Humans MH - *Magnetic Resonance Imaging/is [Instrumentation] MH - *Magnetic Resonance Imaging/mt [Methods] MH - Male MH - Middle Aged MH - Neoplasm Staging MH - *Pelvis/pa [Pathology] MH - Prognosis MH - *Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Treatment Outcome AB - OBJECTIVES: To determine the accuracy and assess the clinical significance of surface-coil 1.5-T magnetic resonance imaging (MRI) for the detection of locally advanced prostate cancer (PCa). AB - METHODS: Between December 2007 and January 2010, we examined 209 PCa patients (mean age=62.5 years) who were consecutively treated with robot-assisted laparoscopic prostatectomy and prospectively staged by MRI. One hundred and thirty-five patients (64.6 %) had locally advanced disease. Conventional clinical tumour stage and MRI-assessed tumour stage were compared with histopathological tumour stage (pT). Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and overall accuracy (OA) were calculated using pT as the "gold standard". Overstaged and understaged cases at MRI were reviewed. AB - RESULTS: Sensitivity, specificity, PPV, NPV and OA for the detection of locally advanced disease were 25.9, 95.9, 92.1, 41.2 and 50.5 % and 56.3, 82.2, 85.4, 50.4 and 65.4 % for clinical staging and MRI, respectively. Among patients understaged at MRI, the resection margins were free in 64.4 % of the cases (38/59). AB - CONCLUSIONS: Although the accuracy was limited, the detection of locally advanced disease improved substantially when MRI was added to routine clinical staging. The majority of the understaged patients nevertheless achieved free margins. When assessing the clinical significance of MRI staging the extent of extraprostatic extension has to be considered. ES - 1432-1084 IL - 0938-7994 DO - https://dx.doi.org/10.1007/s00330-012-2669-x PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 23114883 [pubmed] ID - 10.1007/s00330-012-2669-x [doi] ID - PMC3599204 [pmc] PP - ppublish PH - 2012/05/07 [received] PH - 2012/09/04 [accepted] PH - 2012/08/20 [revised] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01464216 SL - https://clinicaltrials.gov/search/term=NCT01464216 LG - English EP - 20121101 DP - 2013 Apr DC - 20130318 EZ - 2012/11/02 06:00 DA - 2013/09/06 06:00 DT - 2012/11/02 06:00 YR - 2013 ED - 20130905 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23114883 <290. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23114883 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hole KH AU - Axcrona K AU - Lie AK AU - Vlatkovic L AU - Geier OM AU - Brennhovd B AU - Knutstad K AU - Olsen DR AU - Seierstad T FA - Hole, Knut Hakon FA - Axcrona, Karol FA - Lie, Agnes Kathrine FA - Vlatkovic, Ljiljana FA - Geier, Oliver Marcel FA - Brennhovd, Bjorn FA - Knutstad, Kjetil FA - Olsen, Dag Rune FA - Seierstad, Therese IN - Hole, Knut Hakon. Department of Radiology and Nuclear Medicine, Radiumhospitalet, Oslo University Hospital, Montebello, 0310 Oslo, Norway. TI - Routine pelvic MRI using phased-array coil for detection of extraprostatic tumour extension: accuracy and clinical significance. SO - European Radiology. 23(4):1158-66, 2013 Apr AS - Eur Radiol. 23(4):1158-66, 2013 Apr NJ - European radiology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - cl3, 9114774 IO - Eur Radiol PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599204 SB - Index Medicus CP - Germany MH - Adult MH - Aged MH - Equipment Design MH - Equipment Failure Analysis MH - Humans MH - *Magnetic Resonance Imaging/is [Instrumentation] MH - *Magnetic Resonance Imaging/mt [Methods] MH - Male MH - Middle Aged MH - Neoplasm Staging MH - *Pelvis/pa [Pathology] MH - Prognosis MH - *Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Treatment Outcome AB - OBJECTIVES: To determine the accuracy and assess the clinical significance of surface-coil 1.5-T magnetic resonance imaging (MRI) for the detection of locally advanced prostate cancer (PCa). AB - METHODS: Between December 2007 and January 2010, we examined 209 PCa patients (mean age=62.5 years) who were consecutively treated with robot-assisted laparoscopic prostatectomy and prospectively staged by MRI. One hundred and thirty-five patients (64.6 %) had locally advanced disease. Conventional clinical tumour stage and MRI-assessed tumour stage were compared with histopathological tumour stage (pT). Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and overall accuracy (OA) were calculated using pT as the "gold standard". Overstaged and understaged cases at MRI were reviewed. AB - RESULTS: Sensitivity, specificity, PPV, NPV and OA for the detection of locally advanced disease were 25.9, 95.9, 92.1, 41.2 and 50.5 % and 56.3, 82.2, 85.4, 50.4 and 65.4 % for clinical staging and MRI, respectively. Among patients understaged at MRI, the resection margins were free in 64.4 % of the cases (38/59). AB - CONCLUSIONS: Although the accuracy was limited, the detection of locally advanced disease improved substantially when MRI was added to routine clinical staging. The majority of the understaged patients nevertheless achieved free margins. When assessing the clinical significance of MRI staging the extent of extraprostatic extension has to be considered. ES - 1432-1084 IL - 0938-7994 DO - https://dx.doi.org/10.1007/s00330-012-2669-x PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 23114883 [pubmed] ID - 10.1007/s00330-012-2669-x [doi] ID - PMC3599204 [pmc] PP - ppublish PH - 2012/05/07 [received] PH - 2012/09/04 [accepted] PH - 2012/08/20 [revised] LG - English EP - 20121101 DP - 2013 Apr DC - 20130318 EZ - 2012/11/02 06:00 DA - 2013/09/06 06:00 DT - 2012/11/02 06:00 YR - 2013 ED - 20130905 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=23114883 <291. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22840353 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Porpiglia F AU - Morra I AU - Lucci Chiarissi M AU - Manfredi M AU - Mele F AU - Grande S AU - Ragni F AU - Poggio M AU - Fiori C FA - Porpiglia, Francesco FA - Morra, Ivano FA - Lucci Chiarissi, Marco FA - Manfredi, Matteo FA - Mele, Fabrizio FA - Grande, Susanna FA - Ragni, Francesca FA - Poggio, Massimiliano FA - Fiori, Cristian IN - Porpiglia, Francesco. Division of Urology, San Luigi Gonzaga Hospital-Orbassano (Turin), University of Turin, Turin, Italy. porpiglia@libero.it TI - Randomised controlled trial comparing laparoscopic and robot-assisted radical prostatectomy. CM - Comment in: Eur Urol. 2013 Apr;63(4):615-6; discussion 616-7; PMID: 22939384 SO - European Urology. 63(4):606-14, 2013 Apr AS - Eur Urol. 63(4):606-14, 2013 Apr NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Adult MH - Aged MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - *Postoperative Complications/ep [Epidemiology] MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - Recovery of Function MH - *Robotics/mt [Methods] MH - Treatment Outcome MH - *Urinary Incontinence/su [Surgery] AB - BACKGROUND: The advantages of robot-assisted radical prostatectomy (RARP) over laparoscopic radical prostatectomy (LRP) have rarely been investigated in randomised controlled trials. AB - OBJECTIVE: To compare RARP and LRP in terms of the functional, perioperative, and oncologic outcomes. The main end point of the study was changes in continence 3 mo after surgery. AB - DESIGN, SETTING, AND PARTICIPANTS: From January 2010 to January 2011, 120 patients with organ-confined prostate cancer were enrolled and randomly assigned (using a randomisation plan) to one of two groups based on surgical approach: the RARP group and the LRP group. AB - INTERVENTION: All RARP and LRP interventions were performed with the same technique by the same single surgeon. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: The demographic, perioperative, and pathologic results, such as the complications and prostate-specific antigen (PSA) measurements, were recorded and compared. Continence was evaluated at the time of catheter removal and 48 h later, and continence and potency were evaluated after 1, 3, 6, and 12 mo. The student t test, Mann-Whitney test, chi(2) test, Pearson chi(2) test, and multiple regression analysis were used for statistics. AB - RESULTS AND LIMITATIONS: The two groups (RARP: n=60; LRP: n=60) were comparable in terms of demographic data. No differences were recorded in terms of perioperative and pathologic results, complication rate, or PSA measurements. The continence rate was higher in the RARP group at every time point: Continence after 3 mo was 80% in the RARP group and 61.6% in the LRP group (p=0.044), and after 1 yr, the continence rate was 95.0% and 83.3%, respectively (p=0.042). Among preoperative potent patients treated with nerve-sparing techniques, the rate of erection recovery was 80.0% and 54.2%, respectively (p=0.020). The limitations included the small number of patients. AB - CONCLUSIONS: RARP provided better functional results in terms of the recovery of continence and potency. Further studies are needed to confirm our results. AB - Copyright © 2012. Published by Elsevier B.V. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(12)00812-3 DO - https://dx.doi.org/10.1016/j.eururo.2012.07.007 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 22840353 [pubmed] ID - S0302-2838(12)00812-3 [pii] ID - 10.1016/j.eururo.2012.07.007 [doi] PP - ppublish PH - 2012/04/21 [received] PH - 2012/07/09 [accepted] LG - English EP - 20120720 DP - 2013 Apr DC - 20130226 EZ - 2012/07/31 06:00 DA - 2013/08/31 06:00 DT - 2012/07/31 06:00 YR - 2013 ED - 20130830 RD - 20131106 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=22840353 <292. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22801937 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Weidner AC AU - Wu JM AU - Kawasaki A AU - Myers ER FA - Weidner, Alison C FA - Wu, Jennifer M FA - Kawasaki, Amie FA - Myers, Evan R IN - Weidner, Alison C. Division of Urogynecology, Department of Obstetrics and Gynecology, Duke University Medical Center, 5324 McFarland Dr., Suite 310, Durham, NC 27707, USA. alison.weidner@duke.edu TI - Computer modeling informs study design: vaginal estrogen to prevent mesh erosion after different routes of prolapse surgery. SO - International Urogynecology Journal. 24(3):441-5, 2013 Mar AS - Int Urogynecol J Pelvic Floor Dysfunct. 24(3):441-5, 2013 Mar NJ - International urogynecology journal PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - cl5, 9514583, 101567041 IO - Int Urogynecol J SB - Index Medicus CP - England MH - Administration, Intravaginal MH - Colposcopy/mt [Methods] MH - *Computer Simulation MH - *Equipment Failure/sn [Statistics & Numerical Data] MH - Estradiol/ad [Administration & Dosage] MH - *Estradiol/tu [Therapeutic Use] MH - Feasibility Studies MH - Female MH - Follow-Up Studies MH - *Gynecologic Surgical Procedures/mt [Methods] MH - Humans MH - Minimally Invasive Surgical Procedures/mt [Methods] MH - Risk Factors MH - *Surgical Mesh MH - Treatment Outcome MH - *Uterine Prolapse/su [Surgery] AB - INTRODUCTION AND HYPOTHESIS: Many clinicians use perioperative vaginal estrogen therapy (estradiol, E(2)) to diminish the risk of mesh erosion after prolapse surgery, though supporting evidence is limited. We assessed the feasibility of a factorial randomized trial comparing mesh erosion rates after vaginal mesh prolapse surgery (VM) versus minimally invasive sacral colpopexy (MISC), with or without adjunct vaginal estrogen therapy. AB - METHODS: A Markov state transition model simulated the probability of 2-year outcomes of visceral injury, mesh erosion, and reoperation after four possible prolapse therapies: VM or MISC, each with or without estrogen therapy (E(2)). We used pooled estimates from a systematic review to generate probability distributions for the following outcomes after each procedure: visceral injury, postoperative mesh erosion, and reoperation for either recurrent prolapse or mesh erosion. Assuming different assumptions for E(2) efficacies (50 and 75 % reduction in erosion rates), Monte Carlo simulations estimated outcomes rates, which were then used to generate sample size estimates for a four-arm factorial trial. AB - RESULTS: While E(2) reduced the risk of mesh erosion for both VM and MISC, absolute reduction was small. Assuming 75 % efficacy, E(2) decreased the risk of mesh erosion for VM from 7.8 to 2.0 % and for MISC from 2.0 to 0.5 %. Total sample sizes ranged from 448 to 1,620, depending on power and E(2) efficacy. AB - CONCLUSIONS: The required sample size for a trial to determine which therapy results in the lowest erosion rates would be prohibitively large. Because this remains an important clinical issue, further study design strategies could include composite outcomes, cost-effectiveness, or value of information analysis. RN - 4TI98Z838E (Estradiol) ES - 1433-3023 IL - 0937-3462 DO - https://dx.doi.org/10.1007/s00192-012-1877-x PT - Journal Article PT - Randomized Controlled Trial ID - 22801937 [pubmed] ID - 10.1007/s00192-012-1877-x [doi] PP - ppublish PH - 2012/03/28 [received] PH - 2012/06/23 [accepted] LG - English EP - 20120717 DP - 2013 Mar DC - 20130226 EZ - 2012/07/18 06:00 DA - 2013/08/31 06:00 DT - 2012/07/18 06:00 YR - 2013 ED - 20130830 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=22801937 <293. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22956399 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Chien JH AU - Suh IH AU - Park SH AU - Mukherjee M AU - Oleynikov D AU - Siu KC FA - Chien, Jung Hung FA - Suh, Irene H FA - Park, Shi-Hyun FA - Mukherjee, Mukul FA - Oleynikov, Dmitry FA - Siu, Ka-Chun IN - Chien, Jung Hung. University of Nebraska Medical Center, Omaha, NE 68182, USA. jchien@unomaha.edu TI - Enhancing fundamental robot-assisted surgical proficiency by using a portable virtual simulator. SO - Surgical Innovation. 20(2):198-203, 2013 Apr AS - Surg Innov. 20(2):198-203, 2013 Apr NJ - Surgical innovation PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101233809 IO - Surg Innov SB - Index Medicus CP - United States MH - *Education, Medical/mt [Methods] MH - Humans MH - Imaging, Three-Dimensional MH - *Laparoscopy/ed [Education] MH - Laparoscopy/is [Instrumentation] MH - *Laparoscopy/mt [Methods] MH - *Robotics/ed [Education] MH - Robotics/is [Instrumentation] MH - *Robotics/mt [Methods] MH - Students, Medical MH - Surgery, Computer-Assisted/ed [Education] MH - Surgery, Computer-Assisted/is [Instrumentation] MH - Surgery, Computer-Assisted/mt [Methods] MH - *User-Computer Interface MH - Video Games AB - BACKGROUND: The development of a virtual reality (VR) training platform provides an affordable interface. The learning effect of VR and the capability of skill transfer from the VR environment to clinical tasks require more investigation. AB - METHODS: Here, 14 medical students performed 2 fundamental surgical tasks-bimanual carrying (BC) and peg transfer (PT)-in actual and virtual environments. Participants in the VR group received VR training, whereas participants in the control group played a 3D game. The learning effect was examined by comparing kinematics between pretraining and posttraining in the da Vinci Surgical System. Differences between VR and playing the 3D game were also examined. AB - RESULTS: Those who were trained with the VR simulator had significantly better performance in both actual PT (P = .002) and BC (P < .001) tasks. The time to task completion and the total distance traveled were significantly decreased in both surgical tasks in the VR group compared with the 3D game group. However, playing the 3D game showed no significant enhancement of fundamental surgical skills in the actual PT task. The difference between pretraining and posttraining was significantly larger in the VR group than in the 3D game group in both the time to task completion (P = .002) and the total distance traveled (P = .027) for the actual PT task. Participants who played the 3D game seemed to perform even worse in posttraining. AB - CONCLUSIONS: Training with the portable VR simulator improved robot-assisted surgical skill proficiency in comparison to playing a 3D game. ES - 1553-3514 IL - 1553-3506 DI - 1553350612458545 DO - https://dx.doi.org/10.1177/1553350612458545 PT - Journal Article PT - Randomized Controlled Trial ID - 22956399 [pubmed] ID - 1553350612458545 [pii] ID - 10.1177/1553350612458545 [doi] PP - ppublish LG - English EP - 20120906 DP - 2013 Apr DC - 20130305 EZ - 2012/09/08 06:00 DA - 2013/08/29 06:00 DT - 2012/09/08 06:00 YR - 2013 ED - 20130828 RD - 20130305 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=22956399 <294. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22696026 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kang J AU - Park MG AU - Hur H AU - Min BS AU - Lee KY AU - Kim NK FA - Kang, Jeonghyun FA - Park, Min Geun FA - Hur, Hyuk FA - Min, Byung Soh FA - Lee, Kang Young FA - Kim, Nam Kyu IN - Kang, Jeonghyun. Yonsei University College of Medicine, Seoul, South Korea. TI - Safety and efficacy of the NiTi Shape Memory Compression Anastomosis Ring (CAR/ColonRing) for end-to-end compression anastomosis in anterior resection or low anterior resection. SO - Surgical Innovation. 20(2):164-70, 2013 Apr AS - Surg Innov. 20(2):164-70, 2013 Apr NJ - Surgical innovation PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101233809 IO - Surg Innov SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - Anastomosis, Surgical/ae [Adverse Effects] MH - *Anastomosis, Surgical/is [Instrumentation] MH - Anastomosis, Surgical/mt [Methods] MH - Chi-Square Distribution MH - *Colorectal Neoplasms/su [Surgery] MH - Female MH - Humans MH - Male MH - Middle Aged MH - Perioperative Period/mt [Methods] MH - Prospective Studies MH - Republic of Korea AB - PURPOSE: Compression anastomoses may represent an improvement over traditional hand-sewn or stapled techniques. This prospective exploratory study aimed to assess the efficacy and complication rates in patients undergoing anterior resection (AR) or low anterior resection (LAR) anastomosed with a novel end-to-end compression anastomosis ring, the ColonRing. AB - METHODS: In all, 20 patients (13 male) undergoing AR or LAR were enrolled to be anastomosed using the NiTi Shape Memory End-to-End Compression Anastomosis Ring (NiTi Medical Technologies Ltd, Netanya, Israel). Demographic, intraoperative, and postoperative data were collected. AB - RESULTS: Patients underwent AR (11/20) or LAR using laparoscopy (75%), robotic (10%) surgery, or an open laparotomy (15%) approach, with a median anastomotic level of 14.5 cm (range, 4-25 cm). Defunctioning loop ileostomies were formed in 6 patients for low anastomoses. Surgeons rated the ColonRing device as either easy or very easy to use. One patient developed an anastomotic leakage in the early postoperative period; there were no late postoperative complications. Mean time to passage of first flatus and commencement of oral fluids was 2.5 days and 3.2 days, respectively. Average hospital stay was 12.6 days (range, 8-23 days). Finally, the device was expelled on average 15.3 days postoperatively without difficulty. AB - CONCLUSIONS: This is the first study reporting results in a significant number of LAR patients and the first reported experience from South Korea; it shows that the compression technique is surgically feasible, easy to use, and without significant complication rates. A large randomized controlled trial is warranted to investigate the benefits of the ColonRing over traditional stapling techniques. ES - 1553-3514 IL - 1553-3506 DI - 1553350612449073 DO - https://dx.doi.org/10.1177/1553350612449073 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 22696026 [pubmed] ID - 1553350612449073 [pii] ID - 10.1177/1553350612449073 [doi] PP - ppublish LG - English EP - 20120613 DP - 2013 Apr DC - 20130305 EZ - 2012/06/15 06:00 DA - 2013/08/29 06:00 DT - 2012/06/15 06:00 YR - 2013 ED - 20130828 RD - 20130305 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=22696026 <295. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23465473 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - PubMed-not-MEDLINE AU - Kane C FA - Kane, Christopher TI - Commentary on "anterior suspension combined with posterior reconstruction during robot-assisted laparoscopic prostatectomy improves early return of urinary continence: A prospective randomized multicentre trial." Hurtes X, Roupret M, Vaessen C, Pereira H, d'Arcier BF, Cormier L, Bruyere F, Urology Department, University Hospital of Tours, Tours, France: BJU Int 2012;110(6):875-83. CM - Comment on: BJU Int. 2012 Sep;110(6):875-83; PMID: 22260307 SO - Urologic Oncology. 31(2):272-3, 2013 Feb AS - UROL. ONCOL.. 31(2):272-3, 2013 Feb NJ - Urologic oncology PI - Journal available in: Print PI - Citation processed from: Internet JC - 9805460 IO - Urol. Oncol. CP - United States AB - UNLABELLED: What's known on the subject? and What does the study add? Urinary incontinence is one of the major drawbacks of radical prostatectomy, regardless of the procedure used (i.e. open, laparoscopic or robotic-assisted). Several technical modifications have been described to improve postoperative continence, highlighting the role of puboprostatic ligaments and posterior reconstruction of the rhabdomyosphincter. The results obtained are inconsistent when applied to robotic surgery. The present multicentre randomized study shows that anterior suspension combined with posterior reconstruction is a safe and easy-to-perform technique for improving early continence after robotic-assisted laparoscopic prostatectomy. AB - OBJECTIVE: To assess the impact on urinary continence of anterior retropubic suspension with posterior reconstruction during robot-assisted laparoscopic prostatectomy (RALP). AB - PATIENTS AND METHODS: In total, 72 patients who were due to undergo prostatectomy between July 2009 and July 2010 were prospectively randomized into two groups: group A underwent a standard RALP procedure and group B had anterior suspension and posterior reconstruction during RALP. The primary outcome measure was urinary continence, assessed using the University of California Los Angeles Prostate Cancer Index questionnaire at 15 days, and at 1, 3 and 6 months, after surgery. Other data recorded were operation duration, blood loss, length of hospital stay, duration of bladder catheterization, complications and positive margin rate. AB - RESULTS: The continence rates at 15 days, and at 1, 3 and 6 months, after surgery were 3.6%, 7.1%, 15.4% and 57.9%, respectively, in group A, and 5.9%, 26.5%, 45.2% and 65.4%, respectively, in group B. The continence rates differed statistically between groups at 1 and 3 months (P = 0.047 and P = 0.016, respectively). There was no significant difference between groups regarding complications (P = 0.8) or positive margin rate (P = 0.46). AB - CONCLUSION: Anterior suspension associated with posterior reconstruction during RALP improved the early return of continence, without increasing complications. AB - Copyright © 2013 Elsevier Inc. All rights reserved. ES - 1873-2496 IL - 1078-1439 DI - S1078-1439(13)00065-3 DO - https://dx.doi.org/10.1016/j.urolonc.2013.02.002 PT - Comment PT - Journal Article ID - 23465473 [pubmed] ID - S1078-1439(13)00065-3 [pii] ID - 10.1016/j.urolonc.2013.02.002 [doi] PP - ppublish LG - English DP - 2013 Feb DC - 20130307 EZ - 2013/03/08 06:00 DA - 2013/03/08 06:01 DT - 2013/03/08 06:00 YR - 2013 ED - 20130828 RD - 20130307 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=23465473 <296. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23797528 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Robinson BL AU - Parnell BA AU - Sandbulte JT AU - Geller EJ AU - Connolly A AU - Matthews CA FA - Robinson, Barbara L FA - Parnell, Brent A FA - Sandbulte, Jennifer T FA - Geller, Elizabeth J FA - Connolly, AnnaMarie FA - Matthews, Catherine A IN - Robinson, Barbara L. Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Georgia Regents University, Augusta, GA 30912, USA. brobinson.@gru.edu TI - Robotic versus vaginal urogynecologic surgery: a retrospective cohort study of perioperative complications in elderly women. SO - Female Pelvic Medicine & Reconstructive Surgery. 19(4):230-7, 2013 Jul-Aug AS - Female pelvic med. reconstr. surg.. 19(4):230-7, 2013 Jul-Aug NJ - Female pelvic medicine & reconstructive surgery PI - Journal available in: Print PI - Citation processed from: Print JC - 101528690 IO - Female Pelvic Med Reconstr Surg SB - Index Medicus CP - United States MH - Age Factors MH - Aged MH - Aged, 80 and over MH - Body Mass Index MH - Female MH - Health Status MH - Humans MH - *Natural Orifice Endoscopic Surgery/ae [Adverse Effects] MH - Patient Selection MH - *Pelvic Organ Prolapse/su [Surgery] MH - Retrospective Studies MH - Risk Factors MH - *Robotics MH - Treatment Outcome MH - *Urogenital Surgical Procedures/ae [Adverse Effects] MH - *Vagina/su [Surgery] AB - OBJECTIVES: The primary objective was to compare perioperative complications after robotic surgery (RS) versus vaginal surgery (VS) for apical prolapse repair in elderly women. The secondary objectives were to (1) assess whether tools designed to predict surgical morbidity, the American Society of Anesthesiologists (ASA) class and the Charlson Comorbidity Index (CCI), are useful in the elderly urogynecologic population and (2) to classify complications during urogynecologic apical procedures using the Dindo classification system. AB - METHODS: We reviewed medical records of women 65 years or older who underwent RS or VS between March 2006 and April 2011. Procedures included robotic sacrocolpopexy and sacrocervicopexy, vaginal uterosacral ligament suspension, sacrospinous ligament suspension, colpocleisis, and Uphold vaginal mesh placement. We assessed preoperative risks using ASA and CCI classification and complications using Dindo grade. AB - RESULTS: There were 136 eligible cases (RS, 70; and VS, 66) during the 5-year study period. Women who underwent RS were younger (70 vs 74 years; P < 0.001). Vaginal surgery had more severe comorbidities as measured by the CCI (P = 0.012) but similar ASA profiles (P = 0.10). Robotic surgery had longer operative times (P < 0.001) but a lower estimated blood loss (P < 0.001). There were fewer postoperative complications in RS (P = 0.005). However, complication severity based on Dindo grade was similar between RS and VS, with most surgeries having no complications. AB - CONCLUSIONS: In the elderly women, RS was associated with fewer postoperative complications than VS. Overall, all procedures were associated with few complications, and either route may be reasonable in the elderly population. IS - 2151-8378 IL - 2151-8378 DI - 01436319-201307000-00010 DO - https://dx.doi.org/10.1097/SPV.0b013e318299a66c PT - Comparative Study PT - Journal Article ID - 23797528 [pubmed] ID - 10.1097/SPV.0b013e318299a66c [doi] ID - 01436319-201307000-00010 [pii] PP - ppublish LG - English DP - 2013 Jul-Aug DC - 20130626 EZ - 2013/06/26 06:00 DA - 2013/08/28 06:00 DT - 2013/06/26 06:00 YR - 2013 ED - 20130827 RD - 20130626 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23797528 <297. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23348954 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kadono Y AU - Yaegashi H AU - Machioka K AU - Ueno S AU - Miwa S AU - Maeda Y AU - Miyagi T AU - Mizokami A AU - Fujii Y AU - Tsubokawa T AU - Yamamoto K AU - Namiki M FA - Kadono, Yoshifumi FA - Yaegashi, Hiroshi FA - Machioka, Kazuaki FA - Ueno, Satoru FA - Miwa, Sotaro FA - Maeda, Yuji FA - Miyagi, Tohru FA - Mizokami, Atsushi FA - Fujii, Yuka FA - Tsubokawa, Tsunehisa FA - Yamamoto, Ken FA - Namiki, Mikio IN - Kadono, Yoshifumi. Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Japan. yskadono@yahoo.co.jp TI - Cardiovascular and respiratory effects of the degree of head-down angle during robot-assisted laparoscopic radical prostatectomy. SO - The International Journal Of Medical Robotics + Computer Assisted Surgery: MRCAS. 9(1):17-22, 2013 Mar AS - Int J Med Robot. 9(1):17-22, 2013 Mar NJ - The international journal of medical robotics + computer assisted surgery : MRCAS PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101250764 IO - Int J Med Robot SB - Index Medicus CP - England MH - Aged MH - Blood Pressure/ph [Physiology] MH - *Head-Down Tilt/ph [Physiology] MH - *Heart Rate/ph [Physiology] MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - *Patient Positioning/mt [Methods] MH - *Prostatectomy/mt [Methods] MH - *Respiratory Rate/ph [Physiology] MH - *Robotics/mt [Methods] MH - Surgery, Computer-Assisted/mt [Methods] AB - BACKGROUND: Robot-assisted laparoscopic radical prostatectomy (RALP) requires a steep Trendelenburg position and CO2 pneumoperitoneum for several hours to secure the surgical visual field. The present study was performed to investigate the influence of each angle of Trendelenburg position during RALP on cardiovascular and respiratory homeostasis. AB - METHODS: Forty-seven ASA physical status 1 and 2 patients underwent open retropubic radical prostatectomy (RRP) or RALP. Patients receiving RALP were randomized to undergo the operation in the 20degree, 25degree or 30degree Trendelenburg position. Heart rate (HR), mean arterial pressure (MAP), respiratory rate (RR), end-tidal CO2 pressure (PetCO2 ), tidal volume (Vt), peak inspiratory pressure (PIP) and dynamic compliance (Cdyn) were recorded during the operation. AB - RESULTS: Angle of head-down tilt was significantly correlated with MAP, PIP and Cdyn, but not with HR, RR or PetCO2 . MAP decreased gradually over time in each group in the Trendelenburg position with pneumoperitoneum. As the angle of head-down tilt became stronger, MAP, RR, PetCO2 and PIP tended to increase and Cdyn tended to decrease. AB - CONCLUSIONS: This study demonstrated that the degree of the head-down angle at RALP affected the cardiovascular and respiratory parameters. Pneumoperitoneum with head-down position in RALP influenced the cardiovascular and respiratory system to a greater extent than RRP, and these effects were stronger with deeper head-down angle. AB - Copyright © 2013 John Wiley & Sons, Ltd. ES - 1478-596X IL - 1478-5951 DO - https://dx.doi.org/10.1002/rcs.1482 PT - Journal Article PT - Randomized Controlled Trial ID - 23348954 [pubmed] ID - 10.1002/rcs.1482 [doi] PP - ppublish PH - 2012/12/06 [accepted] LG - English EP - 20130125 DP - 2013 Mar DC - 20130306 EZ - 2013/01/26 06:00 DA - 2013/08/22 06:00 DT - 2013/01/26 06:00 YR - 2013 ED - 20130821 RD - 20130826 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23348954 <298. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23365899 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Miura S AU - Kobayashi Y AU - Kawamura K AU - Seki M AU - Nakashima Y AU - Noguchi T AU - Kasuya M AU - Yokoo Y AU - Fujie MG FA - Miura, Satoshi FA - Kobayashi, Yo FA - Kawamura, Kazuya FA - Seki, Masatoshi FA - Nakashima, Yasutaka FA - Noguchi, Takehiko FA - Kasuya, Masahiro FA - Yokoo, Yuki FA - Fujie, Masakatsu G IN - Miura, Satoshi. Graduate School of Science and Engineering, Waseda University, Tokyo, Japan. miura-s@akane.waseda.jp TI - Intuitive operability evaluation of surgical robot using brain activity measurement to determine immersive reality. SO - Conference Proceedings: ... Annual International Conference of the IEEE Engineering in Medicine & Biology Society. 2012:337-43, 2012 AS - Conf Proc IEEE Eng Med Biol Soc. 2012:337-43, 2012 NJ - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference PI - Journal available in: Print PI - Citation processed from: Internet JC - 101243413 IO - Conf Proc IEEE Eng Med Biol Soc SB - Index Medicus CP - United States MH - Adult MH - *Brain/pp [Physiopathology] MH - Female MH - Humans MH - Male MH - Neurosurgical Procedures/is [Instrumentation] MH - Neurosurgical Procedures/mt [Methods] MH - *Neurosurgical Procedures MH - Robotics/is [Instrumentation] MH - Robotics/mt [Methods] MH - *Robotics MH - *User-Computer Interface AB - Surgical robots have improved considerably in recent years, but intuitive operability, which represents user inter-operability, has not been quantitatively evaluated. Therefore, for design of a robot with intuitive operability, we propose a method to measure brain activity to determine intuitive operability. The objective of this paper is to determine the master configuration against the monitor that allows users to perceive the manipulator as part of their own body. We assume that the master configuration produces an immersive reality experience for the user of putting his own arm into the monitor. In our experiments, as subjects controlled the hand controller to position the tip of the virtual slave manipulator on a target in a surgical simulator, we measured brain activity through brain-imaging devices. We performed our experiments for a variety of master manipulator configurations with the monitor position fixed. For all test subjects, we found that brain activity was stimulated significantly when the master manipulator was located behind the monitor. We conclude that this master configuration produces immersive reality through the body image, which is related to visual and somatic sense feedback. IS - 1557-170X IL - 1557-170X DO - https://dx.doi.org/10.1109/EMBC.2012.6345938 PT - Clinical Trial PT - Journal Article ID - 23365899 [pubmed] ID - 10.1109/EMBC.2012.6345938 [doi] PP - ppublish LG - English DP - 2012 DC - 20130131 EZ - 2013/02/01 06:00 DA - 2013/08/07 06:00 DT - 2013/02/01 06:00 YR - 2012 ED - 20130806 RD - 20140821 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=23365899 <299. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23052515 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Shin S AU - Bai SJ AU - Rha KH AU - So Y AU - Oh YJ FA - Shin, Seokyung FA - Bai, Sun Joon FA - Rha, Koon Ho FA - So, Yun FA - Oh, Young Jun IN - Shin, Seokyung. Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Korea. skshin@yuhs.ac TI - The effects of combined epidural and general anesthesia on the autonomic nervous system and bioavailability of nitric oxide in patients undergoing laparoscopic pelvic surgery. SO - Surgical Endoscopy. 27(3):918-26, 2013 Mar AS - Surg Endosc. 27(3):918-26, 2013 Mar NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Aged MH - Anesthesia, Epidural MH - Anesthesia, General MH - Anesthetics, Combined/pk [Pharmacokinetics] MH - *Anesthetics, Combined/pd [Pharmacology] MH - *Autonomic Nervous System/de [Drug Effects] MH - Biological Availability MH - Blood Pressure/de [Drug Effects] MH - *Heart Rate/de [Drug Effects] MH - Humans MH - Laparoscopy/mt [Methods] MH - Male MH - Malondialdehyde/me [Metabolism] MH - *Nitric Oxide/pk [Pharmacokinetics] MH - Nitrites/me [Metabolism] MH - *Oxidative Stress/de [Drug Effects] MH - Pneumoperitoneum, Artificial MH - Prostatectomy/mt [Methods] MH - Robotics/mt [Methods] MH - *Sympathetic Nervous System/de [Drug Effects] AB - BACKGROUND: Pneumoperitoneum during laparoscopic surgery is known to affect visceral blood flow and result in oxidative stress. Whether epidural anesthesia will effectively reduce visceral ischemia and oxidative stress by blocking the sympathetic nervous system (SNS) during laparoscopic surgery has not been proven. AB - METHODS: Forty-five patients who were to undergo robot-assisted laparoscopic prostatectomy were randomly assigned to the combined general-epidural anesthesia group (group GE, n = 22) or to the general anesthesia group (group G, n = 23). Blood pressure, heart rate, and the balance between sympathetic and parasympathetic nervous system activity as measured by heart rate variability were recorded at 10 min after induction of anesthesia (T1), 60 (T2) and 120 (T3) min after intra-abdominal CO(2) insufflation, and 10 min after returning the patient to the supine position following CO(2) exsufflation (T4). Arterial blood gas analysis and blood sampling for measurements of nitrite (NO(2-)) and malondialdehyde (MDA) were performed at all time points. AB - RESULTS: Intraoperative mean blood pressure was significantly lower in group GE compared with group G. The low-frequency to high-frequency ratio was significantly increased after induction of pneumoperitoneum in group G but was unchanged in group GE. Plasma levels of nitrite decreased after pneumoperitoneum induction in group G while there was no change in group GE. A significant increase in MDA levels was seen in group G after pneumoperitoneum induction and were higher than group GE at T3 and T4. The 24-h urine output was higher in group GE than in group G on POD 1. The 24-h CrCl was higher in group GE on POD 1 but was not different between groups on POD 2. AB - CONCLUSIONS: Combined epidural and general anesthesia effectively blocks SNS stimulation during laparoscopic surgery and reduces NO inactivation and oxidative stress. RN - 0 (Anesthetics, Combined) RN - 0 (Nitrites) RN - 31C4KY9ESH (Nitric Oxide) RN - 4Y8F71G49Q (Malondialdehyde) ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-012-2536-5 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 23052515 [pubmed] ID - 10.1007/s00464-012-2536-5 [doi] PP - ppublish PH - 2012/04/27 [received] PH - 2012/07/30 [accepted] LG - English EP - 20121006 DP - 2013 Mar DC - 20130214 EZ - 2012/10/12 06:00 DA - 2013/08/03 06:00 DT - 2012/10/12 06:00 YR - 2013 ED - 20130802 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23052515 <300. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23199187 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - van der Sluis PC AU - Ruurda JP AU - van der Horst S AU - Verhage RJ AU - Besselink MG AU - Prins MJ AU - Haverkamp L AU - Schippers C AU - Rinkes IH AU - Joore HC AU - Ten Kate FJ AU - Koffijberg H AU - Kroese CC AU - van Leeuwen MS AU - Lolkema MP AU - Reerink O AU - Schipper ME AU - Steenhagen E AU - Vleggaar FP AU - Voest EE AU - Siersema PD AU - van Hillegersberg R FA - van der Sluis, Pieter C FA - Ruurda, Jelle P FA - van der Horst, Sylvia FA - Verhage, Roy J J FA - Besselink, Marc G H FA - Prins, Margriet J D FA - Haverkamp, Leonie FA - Schippers, Carlo FA - Rinkes, Inne H M Borel FA - Joore, Hans C A FA - Ten Kate, Fiebo Jw FA - Koffijberg, Hendrik FA - Kroese, Christiaan C FA - van Leeuwen, Maarten S FA - Lolkema, Martijn P J K FA - Reerink, Onne FA - Schipper, Marguerite E I FA - Steenhagen, Elles FA - Vleggaar, Frank P FA - Voest, Emile E FA - Siersema, Peter D FA - van Hillegersberg, Richard IN - van der Sluis, Pieter C. Department of Surgery, G04,228, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, CX, 3584, the Netherlands. p.c.vandersluis-2@umcutrecht.nl TI - Robot-assisted minimally invasive thoraco-laparoscopic esophagectomy versus open transthoracic esophagectomy for resectable esophageal cancer, a randomized controlled trial (ROBOT trial). SO - Trials [Electronic Resource]. 13:230, 2012 Nov 30 AS - Trials. 13:230, 2012 Nov 30 NJ - Trials PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101263253 IO - Trials PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564860 SB - Index Medicus CP - England MH - Adenocarcinoma/ec [Economics] MH - Adenocarcinoma/mo [Mortality] MH - Adenocarcinoma/pa [Pathology] MH - *Adenocarcinoma/su [Surgery] MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Carcinoma, Squamous Cell/ec [Economics] MH - Carcinoma, Squamous Cell/mo [Mortality] MH - Carcinoma, Squamous Cell/pa [Pathology] MH - *Carcinoma, Squamous Cell/su [Surgery] MH - Clinical Protocols MH - Cost-Benefit Analysis MH - Esophageal Neoplasms/ec [Economics] MH - Esophageal Neoplasms/mo [Mortality] MH - Esophageal Neoplasms/pa [Pathology] MH - *Esophageal Neoplasms/su [Surgery] MH - Esophagectomy/ae [Adverse Effects] MH - Esophagectomy/ec [Economics] MH - *Esophagectomy/mt [Methods] MH - Esophagectomy/mo [Mortality] MH - Hospital Costs MH - Hospital Mortality MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/ec [Economics] MH - Laparoscopy/mo [Mortality] MH - *Laparoscopy MH - Length of Stay MH - Lymph Node Excision MH - Middle Aged MH - Neoplasm Staging MH - Netherlands MH - Postoperative Complications/mo [Mortality] MH - Quality of Life MH - *Research Design MH - Risk Factors MH - *Robotics MH - Surgery, Computer-Assisted/ae [Adverse Effects] MH - Surgery, Computer-Assisted/ec [Economics] MH - Surgery, Computer-Assisted/mo [Mortality] MH - *Surgery, Computer-Assisted MH - Thoracoscopy/ae [Adverse Effects] MH - Thoracoscopy/ec [Economics] MH - Thoracoscopy/mo [Mortality] MH - *Thoracoscopy MH - Time Factors MH - Treatment Outcome MH - Young Adult AB - BACKGROUND: For esophageal cancer patients, radical esophagolymphadenectomy is the cornerstone of multimodality treatment with curative intent. Transthoracic esophagectomy is the preferred surgical approach worldwide allowing for en-bloc resection of the tumor with the surrounding lymph nodes. However, the percentage of cardiopulmonary complications associated with the transthoracic approach is high (50 to 70%).Recent studies have shown that robot-assisted minimally invasive thoraco-laparoscopic esophagectomy (RATE) is at least equivalent to the open transthoracic approach for esophageal cancer in terms of short-term oncological outcomes. RATE was accompanied with reduced blood loss, shorter ICU stay and improved lymph node retrieval compared with open esophagectomy, and the pulmonary complication rate, hospital stay and perioperative mortality were comparable. The objective is to evaluate the efficacy, risks, quality of life and cost-effectiveness of RATE as an alternative to open transthoracic esophagectomy for treatment of esophageal cancer. AB - METHODS/DESIGN: This is an investigator-initiated and investigator-driven monocenter randomized controlled parallel-group, superiority trial. All adult patients (age > 18 and < 80 years) with histologically proven, surgically resectable (cT1-4a, N0-3, M0) esophageal carcinoma of the intrathoracic esophagus and with European Clinical Oncology Group performance status 0, 1 or 2 will be assessed for eligibility and included after obtaining informed consent. Patients (n = 112) with resectable esophageal cancer are randomized in the outpatient department to either RATE (n = 56) or open three-stage transthoracic esophageal resection (n = 56). The primary outcome of this study is the percentage of overall complications (grade 2 and higher) as stated by the modified Clavien-Dindo classification of surgical complications. AB - DISCUSSION: This is the first randomized controlled trial designed to compare RATE with open transthoracic esophagectomy as surgical treatment for resectable esophageal cancer. If our hypothesis is proven correct, RATE will result in a lower percentage of postoperative complications, lower blood loss, and shorter hospital stay, but with at least similar oncologic outcomes and better postoperative quality of life compared with open transthoracic esophagectomy. The study started in January 2012. Follow-up will be 5 years. Short-term results will be analyzed and published after discharge of the last randomized patient. AB - TRIAL REGISTRATION: Dutch trial register: NTR3291 ClinicalTrial.gov: NCT01544790. RS - Adenocarcinoma Of Esophagus ES - 1745-6215 IL - 1745-6215 DI - 1745-6215-13-230 DO - https://dx.doi.org/10.1186/1745-6215-13-230 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 23199187 [pubmed] ID - 1745-6215-13-230 [pii] ID - 10.1186/1745-6215-13-230 [doi] ID - PMC3564860 [pmc] PP - epublish PH - 2012/05/22 [received] PH - 2012/10/26 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01544790 SL - https://clinicaltrials.gov/search/term=NCT01544790 LG - English EP - 20121130 DP - 2012 Nov 30 DC - 20130206 EZ - 2012/12/04 06:00 DA - 2013/07/20 06:00 DT - 2012/12/04 06:00 YR - 2012 ED - 20130719 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=23199187 <301. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23199187 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - van der Sluis PC AU - Ruurda JP AU - van der Horst S AU - Verhage RJ AU - Besselink MG AU - Prins MJ AU - Haverkamp L AU - Schippers C AU - Rinkes IH AU - Joore HC AU - Ten Kate FJ AU - Koffijberg H AU - Kroese CC AU - van Leeuwen MS AU - Lolkema MP AU - Reerink O AU - Schipper ME AU - Steenhagen E AU - Vleggaar FP AU - Voest EE AU - Siersema PD AU - van Hillegersberg R FA - van der Sluis, Pieter C FA - Ruurda, Jelle P FA - van der Horst, Sylvia FA - Verhage, Roy J J FA - Besselink, Marc G H FA - Prins, Margriet J D FA - Haverkamp, Leonie FA - Schippers, Carlo FA - Rinkes, Inne H M Borel FA - Joore, Hans C A FA - Ten Kate, Fiebo Jw FA - Koffijberg, Hendrik FA - Kroese, Christiaan C FA - van Leeuwen, Maarten S FA - Lolkema, Martijn P J K FA - Reerink, Onne FA - Schipper, Marguerite E I FA - Steenhagen, Elles FA - Vleggaar, Frank P FA - Voest, Emile E FA - Siersema, Peter D FA - van Hillegersberg, Richard IN - van der Sluis, Pieter C. Department of Surgery, G04,228, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, CX, 3584, the Netherlands. p.c.vandersluis-2@umcutrecht.nl TI - Robot-assisted minimally invasive thoraco-laparoscopic esophagectomy versus open transthoracic esophagectomy for resectable esophageal cancer, a randomized controlled trial (ROBOT trial). SO - Trials [Electronic Resource]. 13:230, 2012 Nov 30 AS - Trials. 13:230, 2012 Nov 30 NJ - Trials PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101263253 IO - Trials PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564860 SB - Index Medicus CP - England MH - Adenocarcinoma/ec [Economics] MH - Adenocarcinoma/mo [Mortality] MH - Adenocarcinoma/pa [Pathology] MH - *Adenocarcinoma/su [Surgery] MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Carcinoma, Squamous Cell/ec [Economics] MH - Carcinoma, Squamous Cell/mo [Mortality] MH - Carcinoma, Squamous Cell/pa [Pathology] MH - *Carcinoma, Squamous Cell/su [Surgery] MH - Clinical Protocols MH - Cost-Benefit Analysis MH - Esophageal Neoplasms/ec [Economics] MH - Esophageal Neoplasms/mo [Mortality] MH - Esophageal Neoplasms/pa [Pathology] MH - *Esophageal Neoplasms/su [Surgery] MH - Esophagectomy/ae [Adverse Effects] MH - Esophagectomy/ec [Economics] MH - *Esophagectomy/mt [Methods] MH - Esophagectomy/mo [Mortality] MH - Hospital Costs MH - Hospital Mortality MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/ec [Economics] MH - Laparoscopy/mo [Mortality] MH - *Laparoscopy MH - Length of Stay MH - Lymph Node Excision MH - Middle Aged MH - Neoplasm Staging MH - Netherlands MH - Postoperative Complications/mo [Mortality] MH - Quality of Life MH - *Research Design MH - Risk Factors MH - *Robotics MH - Surgery, Computer-Assisted/ae [Adverse Effects] MH - Surgery, Computer-Assisted/ec [Economics] MH - Surgery, Computer-Assisted/mo [Mortality] MH - *Surgery, Computer-Assisted MH - Thoracoscopy/ae [Adverse Effects] MH - Thoracoscopy/ec [Economics] MH - Thoracoscopy/mo [Mortality] MH - *Thoracoscopy MH - Time Factors MH - Treatment Outcome MH - Young Adult AB - BACKGROUND: For esophageal cancer patients, radical esophagolymphadenectomy is the cornerstone of multimodality treatment with curative intent. Transthoracic esophagectomy is the preferred surgical approach worldwide allowing for en-bloc resection of the tumor with the surrounding lymph nodes. However, the percentage of cardiopulmonary complications associated with the transthoracic approach is high (50 to 70%).Recent studies have shown that robot-assisted minimally invasive thoraco-laparoscopic esophagectomy (RATE) is at least equivalent to the open transthoracic approach for esophageal cancer in terms of short-term oncological outcomes. RATE was accompanied with reduced blood loss, shorter ICU stay and improved lymph node retrieval compared with open esophagectomy, and the pulmonary complication rate, hospital stay and perioperative mortality were comparable. The objective is to evaluate the efficacy, risks, quality of life and cost-effectiveness of RATE as an alternative to open transthoracic esophagectomy for treatment of esophageal cancer. AB - METHODS/DESIGN: This is an investigator-initiated and investigator-driven monocenter randomized controlled parallel-group, superiority trial. All adult patients (age > 18 and < 80 years) with histologically proven, surgically resectable (cT1-4a, N0-3, M0) esophageal carcinoma of the intrathoracic esophagus and with European Clinical Oncology Group performance status 0, 1 or 2 will be assessed for eligibility and included after obtaining informed consent. Patients (n = 112) with resectable esophageal cancer are randomized in the outpatient department to either RATE (n = 56) or open three-stage transthoracic esophageal resection (n = 56). The primary outcome of this study is the percentage of overall complications (grade 2 and higher) as stated by the modified Clavien-Dindo classification of surgical complications. AB - DISCUSSION: This is the first randomized controlled trial designed to compare RATE with open transthoracic esophagectomy as surgical treatment for resectable esophageal cancer. If our hypothesis is proven correct, RATE will result in a lower percentage of postoperative complications, lower blood loss, and shorter hospital stay, but with at least similar oncologic outcomes and better postoperative quality of life compared with open transthoracic esophagectomy. The study started in January 2012. Follow-up will be 5 years. Short-term results will be analyzed and published after discharge of the last randomized patient. AB - TRIAL REGISTRATION: Dutch trial register: NTR3291 ClinicalTrial.gov: NCT01544790. RS - Adenocarcinoma Of Esophagus ES - 1745-6215 IL - 1745-6215 DI - 1745-6215-13-230 DO - https://dx.doi.org/10.1186/1745-6215-13-230 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 23199187 [pubmed] ID - 1745-6215-13-230 [pii] ID - 10.1186/1745-6215-13-230 [doi] ID - PMC3564860 [pmc] PP - epublish PH - 2012/05/22 [received] PH - 2012/10/26 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01544790 SA - ClinicalTrials.gov/NCT01544790 SL - https://clinicaltrials.gov/search/term=NCT01544790 SL - https://clinicaltrials.gov/search/term=NCT01544790 LG - English EP - 20121130 DP - 2012 Nov 30 DC - 20130206 EZ - 2012/12/04 06:00 DA - 2013/07/20 06:00 DT - 2012/12/04 06:00 YR - 2012 ED - 20130719 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=23199187 <302. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23583618 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lendvay TS AU - Brand TC AU - White L AU - Kowalewski T AU - Jonnadula S AU - Mercer LD AU - Khorsand D AU - Andros J AU - Hannaford B AU - Satava RM FA - Lendvay, Thomas S FA - Brand, Timothy C FA - White, Lee FA - Kowalewski, Timothy FA - Jonnadula, Saikiran FA - Mercer, Laina D FA - Khorsand, Derek FA - Andros, Justin FA - Hannaford, Blake FA - Satava, Richard M IN - Lendvay, Thomas S. Department of Urology, University of Washington School of Medicine, Seattle, WA, USA. thomas.lendvay@seattlechildrens.org TI - Virtual reality robotic surgery warm-up improves task performance in a dry laboratory environment: a prospective randomized controlled study. SO - Journal of the American College of Surgeons. 216(6):1181-92, 2013 Jun AS - J Am Coll Surg. 216(6):1181-92, 2013 Jun NJ - Journal of the American College of Surgeons PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - bzb, 9431305 IO - J. Am. Coll. Surg. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082669 OI - Source: NLM. NIHMS538402 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - *Clinical Competence/st [Standards] MH - *Computer Simulation MH - Curriculum/st [Standards] MH - Equipment Design MH - Female MH - Follow-Up Studies MH - Humans MH - *Learning Curve MH - Male MH - *Operating Rooms MH - Prospective Studies MH - *Robotics/ed [Education] MH - Robotics/is [Instrumentation] MH - *Specialties, Surgical/ed [Education] MH - *User-Computer Interface AB - BACKGROUND: Preoperative simulation warm-up has been shown to improve performance and reduce errors in novice and experienced surgeons, yet existing studies have only investigated conventional laparoscopy. We hypothesized that a brief virtual reality (VR) robotic warm-up would enhance robotic task performance and reduce errors. AB - STUDY DESIGN: In a 2-center randomized trial, 51 residents and experienced minimally invasive surgery faculty in General Surgery, Urology, and Gynecology underwent a validated robotic surgery proficiency curriculum on a VR robotic simulator and on the da Vinci surgical robot (Intuitive Surgical Inc). Once they successfully achieved performance benchmarks, surgeons were randomized to either receive a 3- to 5-minute VR simulator warm-up or read a leisure book for 10 minutes before performing similar and dissimilar (intracorporeal suturing) robotic surgery tasks. The primary outcomes compared were task time, tool path length, economy of motion, technical, and cognitive errors. AB - RESULTS: Task time (-29.29 seconds, p = 0.001; 95% CI, -47.03 to -11.56), path length (-79.87 mm; p = 0.014; 95% CI, -144.48 to -15.25), and cognitive errors were reduced in the warm-up group compared with the control group for similar tasks. Global technical errors in intracorporeal suturing (0.32; p = 0.020; 95% CI, 0.06-0.59) were reduced after the dissimilar VR task. When surgeons were stratified by earlier robotic and laparoscopic clinical experience, the more experienced surgeons (n = 17) demonstrated significant improvements from warm-up in task time (-53.5 seconds; p = 0.001; 95% CI, -83.9 to -23.0) and economy of motion (0.63 mm/s; p = 0.007; 95% CI, 0.18-1.09), and improvement in these metrics was not statistically significantly appreciated in the less-experienced cohort (n = 34). AB - CONCLUSIONS: We observed significant performance improvement and error reduction rates among surgeons of varying experience after VR warm-up for basic robotic surgery tasks. In addition, the VR warm-up reduced errors on a more complex task (robotic suturing), suggesting the generalizability of the warm-up. AB - Copyright © 2013 American College of Surgeons. All rights reserved. ES - 1879-1190 IL - 1072-7515 DI - S1072-7515(13)00157-9 DO - https://dx.doi.org/10.1016/j.jamcollsurg.2013.02.012 PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, Non-P.H.S. ID - 23583618 [pubmed] ID - S1072-7515(13)00157-9 [pii] ID - 10.1016/j.jamcollsurg.2013.02.012 [doi] ID - PMC4082669 [pmc] ID - NIHMS538402 [mid] PP - ppublish PH - 2012/11/21 [received] PH - 2013/02/10 [revised] PH - 2013/02/13 [accepted] GI - No: UL1 RR025014 Organization: (RR) *NCRR NIH HHS* Country: United States No: UL1RR025014 Organization: (RR) *NCRR NIH HHS* Country: United States LG - English EP - 20130411 DP - 2013 Jun DC - 20130520 EZ - 2013/04/16 06:00 DA - 2013/07/17 06:00 DT - 2013/04/16 06:00 YR - 2013 ED - 20130716 RD - 20161019 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23583618 <303. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23356829 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Danuser H AU - Di Pierro GB AU - Stucki P AU - Mattei A FA - Danuser, Hansjoerg FA - Di Pierro, Giovanni Battista FA - Stucki, Patrick FA - Mattei, Agostino IN - Danuser, Hansjoerg. Klinik fur Urologie, Luzerner Kantonsspital, Luzern, Switzerland. hansjoerg.danuser@luks.ch TI - Extended pelvic lymphadenectomy and various radical prostatectomy techniques: is pelvic drainage necessary?. SO - BJU International. 111(6):963-9, 2013 May AS - BJU Int. 111(6):963-9, 2013 May NJ - BJU international PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - dcu, 100886721 IO - BJU Int. SB - Index Medicus CP - England MH - Aged MH - Drainage/mt [Methods] MH - *Drainage MH - Humans MH - Lymph Node Excision/mt [Methods] MH - *Lymph Node Excision MH - Lymphocele/et [Etiology] MH - *Lymphocele/pc [Prevention & Control] MH - Male MH - Middle Aged MH - Postoperative Period MH - Prospective Studies MH - *Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/dg [Diagnostic Imaging] MH - *Prostatic Neoplasms/pa [Pathology] MH - Prostatic Neoplasms/su [Surgery] MH - Treatment Outcome MH - Ultrasonography AB - UNLABELLED: WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: The occurence of lymphoceles in patients after radical prostatectomy is well known (2-10%). It appears that patients undergoing open extraperitoneal radical prostatectomy develop more lymphoceles than patients undergoing robot-assisted radical prostatectomy with transperitoneal access. The present study investigates in a prospective randomized manner whether the time of drainage (1 vs 7 days) makes a difference or whether drainage is even necessary. The study data, collected in the same institution, are compared with the incidence of lymphocele in patients treated by robot-assisted radical prostatectomy. AB - OBJECTIVE: To investigate whether routine drainage is advisable after open extended pelvic lymph node dissection (ePLND) and retropubic radical prostatectomy (RRP) by measuring the incidence of lymphoceles and comparing these results with those of a series of robot-assisted radical prostatectomy (RARP) and ePLND. AB - PATIENTS AND METHODS: A total of 331 consecutive patients underwent ePLND and RRP or RARP. The first 132 patients underwent open ePLND and RRP and received two pelvic drains; these patients were prospectively randomized into two groups: group 1 (n = 66), in which the drains were shortened on postoperative (PO) days 3 and 5 and removed on PO day 7, and group 2 (n = 66), in which the drains were removed on PO day 1. The next 199 patients were assigned to two consecutive groups not receiving drainage: group 3 (n = 73) undergoing open ePLND and RRP, followed by group 4 (n = 126) treated by transperitoneal robot-assisted ePLND and RARP. All patients had ultrasonographic controls 5 and 10 days and 3 and 12 months after surgery. AB - RESULTS: Lymphoceles were detected in 6.6% of all patients, 3.3% of whom were asymptomatic and 3.3% of whom were symptomatic. Symptomatic lymphoceles were detected in 0% of group 1, 8% of group 2, 7% of group 3 and 1% of group 4, with groups 2 and 3 differing significantly from group 4 (P < 0.05). In total, 5% of all patients undergoing open RRP (groups 1-3) had symptomatic lymphoceles vs 1% of patients undergoing RARP (group 4) (P = 0.06). Nodal-positive patients had significantly more symptomatic lymphoceles than nodal-negative patients (10% vs 2%) (P < 0.02). AB - CONCLUSIONS: Symptomatic lymphoceles occur less frequently after open RRP and pelvic drainage over 7 days than after open RRP and pelvic drainage over 1 day or without drainage. Patients undergoing RARP without drainage had significantly fewer lymphoceles than patients receiving open RRP without drainage. AB - Copyright © 2013 BJU International. ES - 1464-410X IL - 1464-4096 DO - https://dx.doi.org/10.1111/j.1464-410X.2012.11681.x PT - Journal Article PT - Randomized Controlled Trial ID - 23356829 [pubmed] ID - 10.1111/j.1464-410X.2012.11681.x [doi] PP - ppublish LG - English EP - 20130129 DP - 2013 May DC - 20130425 EZ - 2013/01/30 06:00 DA - 2013/07/10 06:00 DT - 2013/01/30 06:00 YR - 2013 ED - 20130709 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23356829 <304. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21846713 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hippisley-Cox J AU - Coupland C FA - Hippisley-Cox, Julia FA - Coupland, Carol IN - Hippisley-Cox, Julia. Division of Primary Care, University Park, Nottingham NG2 7RD, UK. juliahippisleycox@gmail.com TI - Development and validation of risk prediction algorithm (QThrombosis) to estimate future risk of venous thromboembolism: prospective cohort study. SO - BMJ. 343:d4656, 2011 Aug 16 AS - BMJ. 343:d4656, 2011 Aug 16 NJ - BMJ (Clinical research ed.) PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 8900488, bmj, 101090866 IO - BMJ PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156826 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - Adult MH - Aged MH - Aged, 80 and over MH - *Algorithms MH - Cohort Studies MH - England/ep [Epidemiology] MH - Female MH - Forecasting MH - Humans MH - Male MH - Middle Aged MH - Predictive Value of Tests MH - Proportional Hazards Models MH - Prospective Studies MH - Pulmonary Embolism/ep [Epidemiology] MH - Pulmonary Embolism/mo [Mortality] MH - Pulmonary Embolism/pc [Prevention & Control] MH - Risk Assessment MH - *Venous Thromboembolism/ep [Epidemiology] MH - Venous Thromboembolism/mo [Mortality] MH - *Venous Thromboembolism/pc [Prevention & Control] MH - Venous Thrombosis/ep [Epidemiology] MH - Venous Thrombosis/mo [Mortality] MH - Venous Thrombosis/pc [Prevention & Control] MH - Wales/ep [Epidemiology] AB - OBJECTIVES: To derive and validate a new clinical risk prediction algorithm (QThrombosis, www.qthrombosis.org) to estimate individual patients' risk of venous thromboembolism. AB - DESIGN: Prospective open cohort study using routinely collected data from general practices. Cox proportional hazards models used in derivation cohort to derive risk equations evaluated at 1 and 5 years. Measures of calibration and discrimination undertaken in validation cohort. AB - SETTING: 564 general practices in England and Wales contributing to the QResearch database. AB - PARTICIPANTS: Patients aged 25-84 years, with no record of pregnancy in the preceding 12 months or any previous venous thromboembolism, and not prescribed oral anticoagulation at baseline: 2,314,701 in derivation cohort and 1,240,602 in validation cohort. Outcomes Incident cases of venous thromboembolism, either deep vein thrombosis or pulmonary embolism, recorded in primary care records or linked cause of death records. AB - RESULTS: The derivation cohort included 14,756 incident cases of venous thromboembolism from 10,095,199 person years of observation (rate of 14.6 per 10,000 person years). The validation cohort included 6913 incident cases from 4,632,694 person years of observation (14.9 per 10,000 person years). Independent predictors included in the final model for men and women were age, body mass index, smoking status, varicose veins, congestive cardiac failure, chronic renal disease, cancer, chronic obstructive pulmonary disease, inflammatory bowel disease, hospital admission in past six months, and current prescriptions for antipsychotic drugs. We also included oral contraceptives, tamoxifen, and hormone replacement therapy in the final model for women. The risk prediction equation explained 33% of the variation in women and 34% in men in the validation cohort evaluated at 5 years The D statistic was 1.43 for women and 1.45 for men. The receiver operating curve statistic was 0.75 for both sexes. The model was well calibrated. AB - CONCLUSIONS: We have developed and validated a new risk prediction model that quantifies absolute risk of thrombosis at 1 and 5 years. It can help identify patients at high risk of venous thromboembolism for prevention. The algorithm is based on simple clinical variables which the patient is likely to know or which are routinely recorded in general practice records. The algorithm could be integrated into general practice clinical computer systems and used to risk assess patients before hospital admission or starting medication which might increase the risk of venous thromboembolism. ES - 1756-1833 IL - 0959-535X DI - bmj.d4656 DO - https://dx.doi.org/10.1136/bmj.d4656 PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 21846713 [pubmed] ID - PMC3156826 [pmc] PP - epublish LG - English EP - 20110816 DP - 2011 Aug 16 DC - 20110817 EZ - 2011/08/18 06:00 DA - 2013/07/09 06:00 DT - 2011/08/19 06:00 YR - 2011 ED - 20130708 RD - 20150204 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21846713 <305. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23561336 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - PubMed-not-MEDLINE AU - Griebling TL FA - Griebling, Tomas L TI - Re: perioperative outcomes of robotic-assisted partial nephrectomy in elderly patients: a matched-cohort study. CM - Comment on: Urology. 2012 May;79(5):1063-7; PMID: 22546384 SO - Journal of Urology. 189(4):1284, 2013 Apr AS - J Urol. 189(4):1284, 2013 Apr NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. CP - United States ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(12)05873-9 DO - https://dx.doi.org/10.1016/j.juro.2012.12.045 PT - Comment PT - Journal Article ID - 23561336 [pubmed] ID - S0022-5347(12)05873-9 [pii] ID - 10.1016/j.juro.2012.12.045 [doi] PP - ppublish PH - 2012/12/13 [accepted] LG - English EP - 20121219 DP - 2013 Apr DC - 20130408 EZ - 2013/04/09 06:00 DA - 2013/04/09 06:01 DT - 2013/04/09 06:00 YR - 2013 ED - 20130708 RD - 20130408 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=23561336 <306. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23618425 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kousgaard MB AU - Siersma V AU - Reventlow S AU - Ertmann R AU - Felding P AU - Waldorff FB FA - Kousgaard, Marius Brostrom FA - Siersma, Volkert FA - Reventlow, Susanne FA - Ertmann, Ruth FA - Felding, Peter FA - Waldorff, Frans Boch IN - Kousgaard, Marius Brostrom. The Research Unit for General Practice and Section of General Practice, Department of Public Health, Faculty of Health Sciences, University of Copenhagen, Oster Farimagsgade 5, P.O. Box 2099, Copenhagen DK-1014, Denmark. marbro@sund.ku.dk TI - The effectiveness of computer reminders for improving quality assessment for point-of-care testing in general practice--a randomized controlled trial. SO - Implementation Science. 8:47, 2013 Apr 23 AS - Implement Sci. 8:47, 2013 Apr 23 NJ - Implementation science : IS PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101258411 IO - Implement Sci PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637803 SB - Index Medicus CP - England MH - Denmark MH - Female MH - *General Practice/st [Standards] MH - Humans MH - Male MH - Middle Aged MH - *Point-of-Care Systems/st [Standards] MH - Quality Assurance, Health Care MH - *Quality Improvement MH - *Reminder Systems/st [Standards] MH - *Therapy, Computer-Assisted/st [Standards] MH - Treatment Outcome AB - BACKGROUND: Computer reminders are increasingly being applied in efforts to improve quality and patient safety. However, research is still needed to establish the effectiveness of different kinds of reminders in various settings. This study aimed to evaluate the effectiveness of computer reminders for improving adherence to a quality assessment scheme for point-of-care testing in general practice. AB - METHOD: The study was conducted as a randomized controlled crossover trial among general practices in the Capital Region of Denmark. The intervention consisted of sending computer reminders (ComRem) to practices not adhering to the guideline recommendations of split testing for hemoglobin and glucose. Practices were randomly allocated into two groups. During the first follow-up period, one of the groups received the ComRem intervention together with the general implementation activities (GIA), while the other group only received the GIA. For the second follow-up period, the intervention was switched between the two groups. Outcomes were measured as split test procedure adherence. AB - RESULTS: A total of 142 practices were randomly allocated to the early intervention group and 144 practices to the late intervention group (the control group in the first follow-up period). In the first intervention period, the mean number of split tests performed in the group receiving ComRem group increased from 1.22 to 3.76 (out of eight possible tests) while the mean number of split tests increased from 1.11 to 2.35 in the group targeted by GIA only (p = 0.0059). After the crossover, a similar effect of reminders was observed. Furthermore, the developments in outcome measures over time showed a strong effect of computer reminders beyond the intervention periods. AB - CONCLUSION: There was a significant effect of computer reminders on adherence to the quality assessment scheme for point-of-care testing. Thus, computer reminders seem to be useful for supporting the implementation of relatively simple procedures for quality and safety. AB - TRIAL REGISTRATION: ClinicalTrials.gov: http://NCT01152177. ES - 1748-5908 IL - 1748-5908 DI - 1748-5908-8-47 DO - https://dx.doi.org/10.1186/1748-5908-8-47 PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 23618425 [pubmed] ID - 1748-5908-8-47 [pii] ID - 10.1186/1748-5908-8-47 [doi] ID - PMC3637803 [pmc] PP - epublish PH - 2012/09/14 [received] PH - 2013/04/16 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01152177 SA - ClinicalTrials.gov/NCT01152177 SL - https://clinicaltrials.gov/search/term=NCT01152177 SL - https://clinicaltrials.gov/search/term=NCT01152177 LG - English EP - 20130423 DP - 2013 Apr 23 DC - 20130429 EZ - 2013/04/27 06:00 DA - 2013/07/05 06:00 DT - 2013/04/27 06:00 YR - 2013 ED - 20130703 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23618425 <307. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23618425 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kousgaard MB AU - Siersma V AU - Reventlow S AU - Ertmann R AU - Felding P AU - Waldorff FB FA - Kousgaard, Marius Brostrom FA - Siersma, Volkert FA - Reventlow, Susanne FA - Ertmann, Ruth FA - Felding, Peter FA - Waldorff, Frans Boch IN - Kousgaard, Marius Brostrom. The Research Unit for General Practice and Section of General Practice, Department of Public Health, Faculty of Health Sciences, University of Copenhagen, Oster Farimagsgade 5, P.O. Box 2099, Copenhagen DK-1014, Denmark. marbro@sund.ku.dk TI - The effectiveness of computer reminders for improving quality assessment for point-of-care testing in general practice--a randomized controlled trial. SO - Implementation Science. 8:47, 2013 Apr 23 AS - Implement Sci. 8:47, 2013 Apr 23 NJ - Implementation science : IS PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101258411 IO - Implement Sci PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637803 SB - Index Medicus CP - England MH - Denmark MH - Female MH - *General Practice/st [Standards] MH - Humans MH - Male MH - Middle Aged MH - *Point-of-Care Systems/st [Standards] MH - Quality Assurance, Health Care MH - *Quality Improvement MH - *Reminder Systems/st [Standards] MH - *Therapy, Computer-Assisted/st [Standards] MH - Treatment Outcome AB - BACKGROUND: Computer reminders are increasingly being applied in efforts to improve quality and patient safety. However, research is still needed to establish the effectiveness of different kinds of reminders in various settings. This study aimed to evaluate the effectiveness of computer reminders for improving adherence to a quality assessment scheme for point-of-care testing in general practice. AB - METHOD: The study was conducted as a randomized controlled crossover trial among general practices in the Capital Region of Denmark. The intervention consisted of sending computer reminders (ComRem) to practices not adhering to the guideline recommendations of split testing for hemoglobin and glucose. Practices were randomly allocated into two groups. During the first follow-up period, one of the groups received the ComRem intervention together with the general implementation activities (GIA), while the other group only received the GIA. For the second follow-up period, the intervention was switched between the two groups. Outcomes were measured as split test procedure adherence. AB - RESULTS: A total of 142 practices were randomly allocated to the early intervention group and 144 practices to the late intervention group (the control group in the first follow-up period). In the first intervention period, the mean number of split tests performed in the group receiving ComRem group increased from 1.22 to 3.76 (out of eight possible tests) while the mean number of split tests increased from 1.11 to 2.35 in the group targeted by GIA only (p = 0.0059). After the crossover, a similar effect of reminders was observed. Furthermore, the developments in outcome measures over time showed a strong effect of computer reminders beyond the intervention periods. AB - CONCLUSION: There was a significant effect of computer reminders on adherence to the quality assessment scheme for point-of-care testing. Thus, computer reminders seem to be useful for supporting the implementation of relatively simple procedures for quality and safety. AB - TRIAL REGISTRATION: ClinicalTrials.gov: http://NCT01152177. ES - 1748-5908 IL - 1748-5908 DI - 1748-5908-8-47 DO - https://dx.doi.org/10.1186/1748-5908-8-47 PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 23618425 [pubmed] ID - 1748-5908-8-47 [pii] ID - 10.1186/1748-5908-8-47 [doi] ID - PMC3637803 [pmc] PP - epublish PH - 2012/09/14 [received] PH - 2013/04/16 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01152177 SL - https://clinicaltrials.gov/search/term=NCT01152177 LG - English EP - 20130423 DP - 2013 Apr 23 DC - 20130429 EZ - 2013/04/27 06:00 DA - 2013/07/05 06:00 DT - 2013/04/27 06:00 YR - 2013 ED - 20130703 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=23618425 <308. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23207683 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kim YM AU - Baek SE AU - Lim JS AU - Hyung WJ FA - Kim, Yoo Min FA - Baek, Song-Ee FA - Lim, Joon Seok FA - Hyung, Woo Jin IN - Kim, Yoo Min. Department of Surgery, Yonsei University College of Medicine, 50 Yonsei-ro Seodaemun-gu, Seoul, 120-752, Korea. TI - Clinical application of image-enhanced minimally invasive robotic surgery for gastric cancer: a prospective observational study. SO - Journal of Gastrointestinal Surgery. 17(2):304-12, 2013 Feb AS - J Gastrointest Surg. 17(2):304-12, 2013 Feb NJ - Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 9706084, c7y IO - J. Gastrointest. Surg. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Feasibility Studies MH - Female MH - *Gastrectomy/mt [Methods] MH - Humans MH - *Imaging, Three-Dimensional MH - Male MH - Middle Aged MH - Minimally Invasive Surgical Procedures MH - Prospective Studies MH - *Robotics MH - *Stomach Neoplasms/su [Surgery] MH - *Surgery, Computer-Assisted/mt [Methods] MH - *Tomography, X-Ray Computed AB - BACKGROUND: This study was performed to validate the feasibility and role of image-guided robotic surgery using preoperative computed tomography (CT) images for the treatment of gastric cancer. AB - METHODS: Twelve patients scheduled to undergo robotic gastrectomy for gastric cancer were registered. Vessels encountered during gastrectomy were reconstructed using 3D software and their anatomical variation was evaluated using preoperatively performed CT-angiography. The vascular information was transferred to a robot console using a multi-input display mode. Radiologic findings acquired from preoperative CT by the radiologist were compared with intraoperative findings of the surgeon. This study is registered with www.clinicaltrials.gov as NCT01338948. AB - RESULTS: All 12 robotic gastrectomies were performed without any problems. All anatomical data acquired using 3D software were transferred successfully during surgery. Intraoperative vascular images depicted vasculatures around the stomach and could identify important vascular variations. During surgery, relevant vascular information led the surgeon to branch sites and facilitated lymphadenectomy around the vessels. Image-guidance during the operation provided a vascular map and enabled the surgeon to avoid accidental bleeding and damage to other organs by preventing vascular injuries. AB - CONCLUSION: Image-guided robotic surgery for gastric cancer using preoperative CT-angiography reconstructed during operation by a surgically trained radiologist who could adjust the images by anticipating the operative procedure was feasible and improved the efficiency of surgery by eliminating the possibility of vascular injuries. ES - 1873-4626 IL - 1091-255X DO - https://dx.doi.org/10.1007/s11605-012-2094-0 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Validation Studies ID - 23207683 [pubmed] ID - 10.1007/s11605-012-2094-0 [doi] PP - ppublish PH - 2012/04/06 [received] PH - 2012/11/13 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01338948 SL - https://clinicaltrials.gov/search/term=NCT01338948 LG - English EP - 20121201 DP - 2013 Feb DC - 20130116 EZ - 2012/12/05 06:00 DA - 2013/07/03 06:00 DT - 2012/12/05 06:00 YR - 2013 ED - 20130701 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23207683 <309. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23484743 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Stegemann AP AU - Ahmed K AU - Syed JR AU - Rehman S AU - Ghani K AU - Autorino R AU - Sharif M AU - Rao A AU - Shi Y AU - Wilding GE AU - Hassett JM AU - Chowriappa A AU - Kesavadas T AU - Peabody JO AU - Menon M AU - Kaouk J AU - Guru KA FA - Stegemann, Andrew P FA - Ahmed, Kamran FA - Syed, Johar R FA - Rehman, Shabnam FA - Ghani, Khurshid FA - Autorino, Ricardo FA - Sharif, Mohamed FA - Rao, Amrith FA - Shi, Yi FA - Wilding, Gregory E FA - Hassett, James M FA - Chowriappa, Ashirwad FA - Kesavadas, Thenkurussi FA - Peabody, James O FA - Menon, Mani FA - Kaouk, Jihad FA - Guru, Khurshid Ahad IN - Stegemann, Andrew P. Roswell Park Cancer Institute, Buffalo, NY 14263, USA. TI - Fundamental skills of robotic surgery: a multi-institutional randomized controlled trial for validation of a simulation-based curriculum. SO - Urology. 81(4):767-74, 2013 Apr AS - Urology. 81(4):767-74, 2013 Apr NJ - Urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Adult MH - Clinical Competence MH - Computer Simulation MH - Curriculum MH - Educational Measurement MH - Humans MH - *Robotics/ed [Education] MH - *Urologic Surgical Procedures/ed [Education] AB - OBJECTIVE: To develop and establish effectiveness of simulation-based robotic curriculum--fundamental skills of robotic surgery (FSRS). AB - METHODS: FSRS curriculum was developed and incorporated into a virtual reality simulator, Robotic Surgical Simulator (RoSS). Fifty-three participants were randomized into an experimental group (EG) or control group (CG). The EG was asked to complete the FSRS and 1 final test on the da Vinci Surgical System (dVSS). The dVSS test consisted of 3 tasks: ball placement, suture pass, and fourth arm manipulation. The CG was directly tested on the dVSS then offered the chance to complete the FSRS and re-tested on the dVSS as a crossover (CO) group. AB - RESULTS: Sixty-five percent of participants had never formally trained using laparoscopic surgery. Ball placement: the EG demonstrated shorter time (142 vs 164 seconds, P = .134) and more precise (1.5 vs 2.5 drops, P = .014). The CO took less time (P <.001) with greater precision (P <.001). Instruments were rarely lost from the field. Suture pass: the EG demonstrated better camera utilization (4.3 vs 3.0, P = .078). Less instrument loss occurred (0.5 vs 1.1, P = .026). Proper camera usage significantly improved (P = .009). Fourth arm manipulation: the EG took less time (132 vs 157 seconds, P = .302). Meanwhile, loss of instruments was less frequent (0.2 vs 0.8, P = .076). Precision in the CO improved significantly (P = .042) and camera control and safe instrument manipulation showed improvement (1.5 vs 3.5, 0.2 vs 0.9, respectively). AB - CONCLUSION: FSRS curriculum is a valid, feasible, and structured curriculum that demonstrates its effectiveness by significant improvements in basic robotic surgery skills. AB - Copyright © 2013 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(12)01582-8 DO - https://dx.doi.org/10.1016/j.urology.2012.12.033 PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't PT - Validation Studies ID - 23484743 [pubmed] ID - S0090-4295(12)01582-8 [pii] ID - 10.1016/j.urology.2012.12.033 [doi] PP - ppublish PH - 2012/11/16 [received] PH - 2012/12/24 [revised] PH - 2012/12/26 [accepted] GI - No: 2211 Organization: *Department of Health* Country: United Kingdom LG - English EP - 20130226 DP - 2013 Apr DC - 20130329 EZ - 2013/03/15 06:00 DA - 2013/06/19 06:00 DT - 2013/03/15 06:00 YR - 2013 ED - 20130617 RD - 20161122 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23484743 <310. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23395927 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Paraiso MF AU - Ridgeway B AU - Park AJ AU - Jelovsek JE AU - Barber MD AU - Falcone T AU - Einarsson JI FA - Paraiso, Marie Fidela R FA - Ridgeway, Beri FA - Park, Amy J FA - Jelovsek, J Eric FA - Barber, Matthew D FA - Falcone, Tommaso FA - Einarsson, Jon I IN - Paraiso, Marie Fidela R. Obstetrics and Gynecology and Women's Health Institute, Cleveland Clinic, Cleveland, OH, USA. paraism@ccf.org TI - A randomized trial comparing conventional and robotically assisted total laparoscopic hysterectomy. CM - Comment in: Am J Obstet Gynecol. 2013 Dec;209(6):594-5; PMID: 23871949 CM - Comment in: Am J Obstet Gynecol. 2013 Dec;209(6):593-4; PMID: 23871948 SO - American Journal of Obstetrics & Gynecology. 208(5):368.e1-7, 2013 May AS - Am J Obstet Gynecol. 208(5):368.e1-7, 2013 May NJ - American journal of obstetrics and gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 3ni, 0370476 IO - Am. J. Obstet. Gynecol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Double-Blind Method MH - Female MH - Follow-Up Studies MH - Humans MH - *Hysterectomy/mt [Methods] MH - Intraoperative Complications MH - *Laparoscopy/mt [Methods] MH - Middle Aged MH - Operative Time MH - Postoperative Complications MH - Prospective Studies MH - Quality of Life MH - Recovery of Function MH - *Robotics MH - Treatment Outcome MH - *Uterine Diseases/su [Surgery] AB - OBJECTIVE: The purpose of this study was to compare operative time and intra- and postoperative complications between total laparoscopic hysterectomy and robotic-assisted total laparoscopic hysterectomy. AB - STUDY DESIGN: This study was a blinded, prospective randomized controlled trial conducted at 2 institutions. Subjects consisted of women who planned laparoscopic hysterectomy for benign indications. Preoperative randomization to total laparoscopic hysterectomy or robotic-assisted total laparoscopic hysterectomy was stratified by surgeon and uterine size (> or <12 weeks). Validated questionnaires, activity assessment scales, and visual analogue scales were administered at baseline and during follow-up evaluation. AB - RESULTS: Sixty-two women gave consent and were enrolled and randomly assigned; 53 women underwent surgery (laparoscopic, 27 women; robot-assisted, 26 women). There were no demographic differences between groups. Compared with laparoscopic hysterectomy, total case time (skin incision to skin closure) was significantly longer in the robot-assisted group (mean difference, +77 minutes; 95% confidence interval, 33-121; P < .001] as was total operating room time (entry into operating room to exit; mean difference, +72 minutes; 95% confidence interval, 14-130; P = .016). Mean docking time was 6 +/- 4 minutes. There were no significant differences between groups in estimated blood loss, pre- and postoperative hematocrit change, and length of stay. There were very few complications, with no difference in individual complication types or total complications between groups. Postoperative pain and return to daily activities were no different between groups. AB - CONCLUSION: Although laparoscopic and robotic-assisted hysterectomies are safe approaches to hysterectomy, robotic-assisted hysterectomy requires a significantly longer operative time. AB - Copyright © 2013 Mosby, Inc. All rights reserved. ES - 1097-6868 IL - 0002-9378 DI - S0002-9378(13)00144-0 DO - https://dx.doi.org/10.1016/j.ajog.2013.02.008 PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 23395927 [pubmed] ID - S0002-9378(13)00144-0 [pii] ID - 10.1016/j.ajog.2013.02.008 [doi] PP - ppublish PH - 2012/11/20 [received] PH - 2013/01/23 [revised] PH - 2013/02/04 [accepted] LG - English EP - 20130208 DP - 2013 May DC - 20130426 EZ - 2013/02/12 06:00 DA - 2013/06/19 06:00 DT - 2013/02/12 06:00 YR - 2013 ED - 20130617 RD - 20140108 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23395927 <311. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23594631 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - PubMed-not-MEDLINE AU - Cadeddu JA FA - Cadeddu, Jeffrey A TI - Re: anterior suspension combined with posterior reconstruction during robot-assisted laparoscopic prostatectomy improves early return of urinary continence: a prospective randomized multicentre trial. CM - Comment on: BJU Int. 2012 Sep;110(6):875-83; PMID: 22260307 SO - Journal of Urology. 189(5):1717, 2013 May AS - J Urol. 189(5):1717, 2013 May NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. CP - United States ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(13)00110-9 DO - https://dx.doi.org/10.1016/j.juro.2013.01.070 PT - Comment PT - Journal Article ID - 23594631 [pubmed] ID - S0022-5347(13)00110-9 [pii] ID - 10.1016/j.juro.2013.01.070 [doi] PP - ppublish PH - 2013/01/21 [accepted] LG - English EP - 20130126 DP - 2013 May DC - 20130418 EZ - 2013/04/19 06:00 DA - 2013/04/19 06:01 DT - 2013/04/19 06:00 YR - 2013 ED - 20130617 RD - 20130418 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=23594631 <312. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22915788 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Malcolme-Lawes LC AU - Lim PB AU - Koa-Wing M AU - Whinnett ZI AU - Jamil-Copley S AU - Hayat S AU - Francis DP AU - Kojodjojo P AU - Davies DW AU - Peters NS AU - Kanagaratnam P FA - Malcolme-Lawes, Louisa C FA - Lim, Phang Boon FA - Koa-Wing, Michael FA - Whinnett, Zachary I FA - Jamil-Copley, Shahnaz FA - Hayat, Sajad FA - Francis, Darrel P FA - Kojodjojo, Pipin FA - Davies, D Wyn FA - Peters, Nicholas S FA - Kanagaratnam, Prapa IN - Malcolme-Lawes, Louisa C. Imperial College Healthcare NHS Trust, St Mary's Hospital, Praed Street, London W2 1NY, UK. TI - Robotic assistance and general anaesthesia improve catheter stability and increase signal attenuation during atrial fibrillation ablation. SO - Europace. 15(1):41-7, 2013 Jan AS - Europace. 15(1):41-7, 2013 Jan NJ - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - dxd, 100883649 IO - Europace SB - Index Medicus CP - England MH - Anesthesia, General/mt [Methods] MH - *Anesthetics, General/tu [Therapeutic Use] MH - *Atrial Fibrillation/di [Diagnosis] MH - *Atrial Fibrillation/su [Surgery] MH - *Catheter Ablation/mt [Methods] MH - Female MH - Heart Conduction System/su [Surgery] MH - Humans MH - Male MH - Middle Aged MH - *Pulmonary Veins/su [Surgery] MH - *Robotics/mt [Methods] MH - *Surgery, Computer-Assisted/mt [Methods] MH - Treatment Outcome AB - AIMS: Recurrent arrhythmias after ablation procedures are often caused by recovery of ablated tissue. Robotic catheter manipulation systems increase catheter tip stability which improves energy delivery and could produce more transmural lesions. We tested this assertion using bipolar voltage attenuation as a marker of lesion quality comparing robotic and manual circumferential pulmonary vein ablation for atrial fibrillation (AF). AB - METHODS AND RESULTS: Twenty patients were randomly assigned to robotic or manual AF ablation at standard radiofrequency (RF) settings for our institution (30 W 60 s manual, 25 W 30 s robotic, R30). A separate group of 10 consecutive patients underwent robotic ablation at increased RF duration, 25 W for 60 s (R60). Lesions were marked on an electroanatomic map before and after ablation to measure distance moved and change in bipolar electrogram amplitude during RF. A total of 1108 lesions were studied (761 robotic, 347 manual). A correlation was identified between voltage attenuation and catheter movement during RF (Spearman's rho -0.929, P < 0.001). The ablation catheter was more stable during robotic RF; 2.9 +/- 2.3 mm (R30) and 2.6 +/- 2.2 mm (R60), both significantly less than the manual group (4.3 +/- 3.0 mm, P < 0.001). Despite improved stability, there was no difference in signal attenuation between the manual and R30 group. However, there was increased signal attenuation in the R60 group (52.4 +/- 19.4%) compared with manual (47.7 +/- 25.4%, P = 0.01). When procedures under general anaesthesia (GA) and conscious sedation were analysed separately, the improvement in signal attenuation in the R60 group was only significant in the procedures under GA. AB - CONCLUSIONS: Robotically assisted ablation has the capability to deliver greater bipolar voltage attenuation compared with manual ablation with appropriate selection of RF parameters. General anaesthesia confers additional benefits of catheter stability and greater signal attenuation. These findings may have a significant impact on outcomes from AF ablation procedures. RN - 0 (Anesthetics, General) ES - 1532-2092 IL - 1099-5129 DI - eus244 DO - https://dx.doi.org/10.1093/europace/eus244 PT - Journal Article PT - Randomized Controlled Trial ID - 22915788 [pubmed] ID - eus244 [pii] ID - 10.1093/europace/eus244 [doi] PP - ppublish GI - No: FS/10/38/28268 Organization: *British Heart Foundation* Country: United Kingdom No: RG/10/11/28457 Organization: *British Heart Foundation* Country: United Kingdom LG - English EP - 20120822 DP - 2013 Jan DC - 20121212 EZ - 2012/08/24 06:00 DA - 2013/06/14 06:00 DT - 2012/08/24 06:00 YR - 2013 ED - 20130613 RD - 20161122 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=22915788 <313. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23500318 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Weisz G AU - Metzger DC AU - Caputo RP AU - Delgado JA AU - Marshall JJ AU - Vetrovec GW AU - Reisman M AU - Waksman R AU - Granada JF AU - Novack V AU - Moses JW AU - Carrozza JP FA - Weisz, Giora FA - Metzger, D Christopher FA - Caputo, Ronald P FA - Delgado, Juan A FA - Marshall, J Jeffrey FA - Vetrovec, George W FA - Reisman, Mark FA - Waksman, Ron FA - Granada, Juan F FA - Novack, Victor FA - Moses, Jeffrey W FA - Carrozza, Joseph P IN - Weisz, Giora. Center for Interventional Vascular Therapy, New York Presbyterian Hospital, Columbia University Medical Center, New York, New York 10032, USA. gw2128@columbia.edu TI - Safety and feasibility of robotic percutaneous coronary intervention: PRECISE (Percutaneous Robotically-Enhanced Coronary Intervention) Study. SO - Journal of the American College of Cardiology. 61(15):1596-600, 2013 Apr 16 AS - J Am Coll Cardiol. 61(15):1596-600, 2013 Apr 16 NJ - Journal of the American College of Cardiology PI - Journal available in: Print PI - Citation processed from: Internet JC - h50, 8301365 IO - J. Am. Coll. Cardiol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Catheters MH - Coronary Angiography MH - Coronary Artery Disease/di [Diagnosis] MH - *Coronary Artery Disease/su [Surgery] MH - Coronary Vessels/pa [Pathology] MH - Coronary Vessels/su [Surgery] MH - Equipment Design/mt [Methods] MH - Equipment Design/st [Standards] MH - Feasibility Studies MH - Female MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/ep [Epidemiology] MH - Myocardial Infarction/et [Etiology] MH - *Myocardial Infarction MH - *Occupational Exposure/pc [Prevention & Control] MH - Operating Rooms/ma [Manpower] MH - Outcome and Process Assessment (Health Care) MH - Percutaneous Coronary Intervention/ae [Adverse Effects] MH - Percutaneous Coronary Intervention/mt [Methods] MH - Percutaneous Coronary Intervention/sn [Statistics & Numerical Data] MH - *Percutaneous Coronary Intervention MH - *Postoperative Complications/ep [Epidemiology] MH - Radiologic Health MH - Risk Assessment MH - Robotics/mt [Methods] MH - Robotics/sn [Statistics & Numerical Data] MH - *Robotics MH - Stents MH - Treatment Outcome AB - OBJECTIVES: The aim of this study was to evaluate the safety as well as the clinical and technical effectiveness of robotic-assisted percutaneous coronary intervention. AB - BACKGROUND: Robotic systems have been suggested to enhance the performance of cardiovascular procedures, as well as to provide protection from the occupational hazards that are associated with interventional practice. AB - METHODS: Patients with coronary artery disease and clinical indications for percutaneous intervention were enrolled. The coronary intervention was performed with the CorPath 200 robotic system, which consists of a remote interventional cockpit and a bedside disposable cassette that enables the operator to advance, retract, and rotate guidewires and catheters. The primary endpoints were clinical procedural success, defined as <30% residual stenosis at the completion of the robotic-assisted procedure without major adverse cardiovascular events within 30 days, and device technical success, defined as the successful manipulation of the intracoronary devices using the robotic system only. AB - RESULTS: A total of 164 patients were enrolled at 9 sites. Percutaneous coronary intervention was completed successfully without conversion to manual operation, and device technical success was achieved in 162 of 164 patients (98.8%). There were no device-related complications. Clinical procedural success was achieved in 160 of 164 patients (97.6%), whereas 4 (2.4%) had periprocedural non-Q-wave myocardial infarctions. No deaths, strokes, Q-wave myocardial infarctions, or revascularization occurred in the 30 days after the procedures. Radiation exposure for the primary operator was 95.2% lower than the levels found at the traditional table position. AB - CONCLUSIONS: This pivotal multicenter study with a robotic-enhanced coronary intervention system demonstrated the safety and feasibility of the system. The robotic remote-control procedure met the expected technical and clinical performance, with significantly lower radiation exposure to the operator. (Evaluation of the Safety and Effectiveness of the CorPath 200 System in Percutaneous Coronary Interventions [PCI] [PRECISE]; NCT01275092). AB - Copyright © 2013 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. ES - 1558-3597 IL - 0735-1097 DI - S0735-1097(13)00628-1 DO - https://dx.doi.org/10.1016/j.jacc.2012.12.045 PT - Clinical Trial PT - Journal Article PT - Multicenter Study PT - Research Support, Non-U.S. Gov't ID - 23500318 [pubmed] ID - S0735-1097(13)00628-1 [pii] ID - 10.1016/j.jacc.2012.12.045 [doi] PP - ppublish PH - 2012/08/02 [received] PH - 2012/11/20 [revised] PH - 2012/12/19 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01275092 SL - https://clinicaltrials.gov/search/term=NCT01275092 LG - English DP - 2013 Apr 16 DC - 20130412 EZ - 2013/03/19 06:00 DA - 2013/06/08 06:00 DT - 2013/03/19 06:00 YR - 2013 ED - 20130607 RD - 20130412 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23500318 <314. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22870922 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lee TE AU - Kim SH AU - Cho YA FA - Lee, Tae-Eun FA - Kim, Seung-Hyun FA - Cho, Yoonae A IN - Lee, Tae-Eun. Department of Ophthalmology, Korea University College of Medicine, Seoul, South Korea. TI - Postoperative changes in spatial localization following exotropia surgery. SO - Current Eye Research. 38(1):210-4, 2013 Jan AS - Curr Eye Res. 38(1):210-4, 2013 Jan NJ - Current eye research PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - dub, 8104312 IO - Curr. Eye Res. SB - Index Medicus CP - England MH - Adolescent MH - Adult MH - Child MH - Child, Preschool MH - Exotropia/pp [Physiopathology] MH - *Exotropia/su [Surgery] MH - *Eye Movements/ph [Physiology] MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Oculomotor Muscles/pp [Physiopathology] MH - *Oculomotor Muscles/su [Surgery] MH - Postoperative Period MH - Prospective Studies MH - Recurrence MH - *Space Perception MH - Treatment Outcome MH - Young Adult AB - PURPOSE: To measure changes in spatial localization following exotropia surgery using a computer touch-screen method of measurement. AB - METHODS: Enrolled in the study were 60 exotropia patients, all of whom had undergone corrective muscle surgeries under general anesthesia: 37 patients had undergone unilateral lateral rectus or bilateral lateral rectus muscle recession procedures (recession group) and 23 patients had undergone unilateral lateral and medial rectus muscle resection (R&R), or unilateral medial rectus resection only (resection group). We evaluated spatial localization by having patients point to targets on a computer touch-screen before surgery, and 1 day and 1 month after surgery. The pointing error, DELTAp, is defined as the difference between the actual location of the target and the pointed-to location of the target by unsigned value, was recorded as the mean of five tests. We compared the extent of postoperative changes in DELTAp between the two groups. AB - RESULTS: The mean DELTAp before surgery did not differ statistically between the two groups (p = 0.93). One day after surgery, however, the postoperative change in DELTAp of the resection group compared with that of the recession group (2.0+/-0.7degree and 0.4+/-0.5degree, respectively) was significant (p = 0.01 and p = 0.86 respectively). AB - CONCLUSIONS: The ability for spatial localization is decreased in patients immediately following medial rectus resection, but is regained by 1 month following surgery. ES - 1460-2202 IL - 0271-3683 DO - https://dx.doi.org/10.3109/02713683.2012.713151 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 22870922 [pubmed] ID - 10.3109/02713683.2012.713151 [doi] PP - ppublish LG - English EP - 20120807 DP - 2013 Jan DC - 20130107 EZ - 2012/08/09 06:00 DA - 2013/06/05 06:00 DT - 2012/08/09 06:00 YR - 2013 ED - 20130604 RD - 20130107 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=22870922 <315. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23088719 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Thomee S AU - Harenstam A AU - Hagberg M FA - Thomee, Sara FA - Harenstam, Annika FA - Hagberg, Mats IN - Thomee, Sara. Occupational and Environmental Medicine, Department of Public Health and Community Medicine, University of Gothenburg, Gothenburg, Sweden. sara.thomee@amm.gu.se TI - Computer use and stress, sleep disturbances, and symptoms of depression among young adults--a prospective cohort study. SO - BMC Psychiatry. 12:176, 2012 Oct 22 AS - BMC Psychiatry. 12:176, 2012 Oct 22 NJ - BMC psychiatry PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 100968559 IO - BMC Psychiatry PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528646 SB - Index Medicus CP - England MH - Cohort Studies MH - *Computers/ut [Utilization] MH - *Depression/ep [Epidemiology] MH - Depression/et [Etiology] MH - Female MH - Follow-Up Studies MH - Humans MH - *Internet/ut [Utilization] MH - Male MH - Prospective Studies MH - *Sleep Wake Disorders/ep [Epidemiology] MH - Sleep Wake Disorders/et [Etiology] MH - *Stress, Psychological/ep [Epidemiology] MH - Stress, Psychological/et [Etiology] MH - Surveys and Questionnaires MH - Sweden/ep [Epidemiology] MH - Time Factors MH - Young Adult AB - BACKGROUND: We have previously studied prospective associations between computer use and mental health symptoms in a selected young adult population. The purpose of this study was to investigate if high computer use is a prospective risk factor for developing mental health symptoms in a population-based sample of young adults. AB - METHODS: The study group was a cohort of young adults (n = 4163), 20-24 years old, who responded to a questionnaire at baseline and 1-year follow-up. Exposure variables included time spent on computer use (CU) in general, email/chat use, computer gaming, CU without breaks, and CU at night causing lost sleep. Mental health outcomes included perceived stress, sleep disturbances, symptoms of depression, and reduced performance due to stress, depressed mood, or tiredness. Prevalence ratios (PRs) were calculated for prospective associations between exposure variables at baseline and mental health outcomes (new cases) at 1-year follow-up for the men and women separately. AB - RESULTS: Both high and medium computer use compared to low computer use at baseline were associated with sleep disturbances in the men at follow-up. High email/chat use was negatively associated with perceived stress, but positively associated with reported sleep disturbances for the men. For the women, high email/chat use was (positively) associated with several mental health outcomes, while medium computer gaming was associated with symptoms of depression, and CU without breaks with most mental health outcomes. CU causing lost sleep was associated with mental health outcomes for both men and women. AB - CONCLUSIONS: Time spent on general computer use was prospectively associated with sleep disturbances and reduced performance for the men. For the women, using the computer without breaks was a risk factor for several mental health outcomes. Some associations were enhanced in interaction with mobile phone use. Using the computer at night and consequently losing sleep was associated with most mental health outcomes for both men and women. Further studies should focus on mechanisms relating information and communication technology (ICT) use to sleep disturbances. ES - 1471-244X IL - 1471-244X DI - 1471-244X-12-176 DO - https://dx.doi.org/10.1186/1471-244X-12-176 PT - Duplicate Publication PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 23088719 [pubmed] ID - 1471-244X-12-176 [pii] ID - 10.1186/1471-244X-12-176 [doi] ID - PMC3528646 [pmc] PP - epublish PH - 2011/12/09 [received] PH - 2012/09/25 [accepted] LG - English EP - 20121022 DP - 2012 Oct 22 DC - 20121224 EZ - 2012/10/24 06:00 DA - 2013/06/01 06:00 DT - 2012/10/24 06:00 YR - 2012 ED - 20130531 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=23088719 <316. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22632109 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Gardiner RA AU - Yaxley J AU - Coughlin G AU - Dunglison N AU - Occhipinti S AU - Younie S AU - Carter R AU - Williams S AU - Medcraft RJ AU - Bennett N AU - Lavin MF AU - Chambers SK FA - Gardiner, Robert A FA - Yaxley, John FA - Coughlin, Geoff FA - Dunglison, Nigel FA - Occhipinti, Stefano FA - Younie, Sandra FA - Carter, Rob FA - Williams, Scott FA - Medcraft, Robyn J FA - Bennett, Nigel FA - Lavin, Martin F FA - Chambers, Suzanne Kathleen IN - Gardiner, Robert A. University of Queensland Centre for Clinical Research, Royal Brisbane Hospital, Queensland, Australia. f.gardiner@uq.edu.au TI - A randomised trial of robotic and open prostatectomy in men with localised prostate cancer. SO - BMC Cancer. 12:189, 2012 May 25 AS - BMC Cancer. 12:189, 2012 May 25 NJ - BMC cancer PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 100967800 IO - BMC Cancer PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515414 SB - Index Medicus CP - England MH - Adult MH - Aged MH - Australia MH - Humans MH - Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - Prostate/pa [Pathology] MH - *Prostate/su [Surgery] MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - Quality of Life MH - *Robotics/mt [Methods] MH - Surveys and Questionnaires MH - Treatment Outcome AB - BACKGROUND: Prostate cancer is the most common male cancer in the Western world however there is ongoing debate about the optimal treatment strategy for localised disease. While surgery remains the most commonly received treatment for localised disease in Australia more recently a robotic approach has emerged as an alternative to open and laparoscopic surgery. However, high level data is not yet available to support this as a superior approach or to guide treatment decision making between the alternatives. This paper presents the design of a randomised trial of Robotic and Open Prostatectomy for men newly diagnosed with localised prostate cancer that seeks to answer this question. AB - METHODS/DESIGN: 200 men per treatment arm (400 men in total) are being recruited after diagnosis and before treatment through a major public hospital outpatient clinic and randomised to 1) Robotic Prostatectomy or 2) Open Prostatectomy. All robotic prostatectomies are being performed by one surgeon and all open prostatectomies are being performed by one other surgeon. Outcomes are being measured pre-operatively and at 6 weeks and 3, 6, 12 and 24 months post-surgery. Oncological outcomes are being related to positive surgical margins, biochemical recurrence +/- the need for further treatment. Non-oncological outcome measures include: pain, physical and mental functioning, fatigue, summary (preference-based utility scores) and domain-specific QoL (urinary incontinence, bowel function and erectile function), cancer specific distress, psychological distress, decision-related distress and time to return to usual activities. Cost modelling of each approach, as well as full economic appraisal, is also being undertaken. AB - DISCUSSION: The study will provide recommendations about the relative benefits of Robotic and Open Prostatectomy to support informed patient decision making about treatment for localised prostate cancer; and to assist in treatment services planning for this patient group. AB - TRIAL REGISTRATION: ACTRN12611000661976. ES - 1471-2407 IL - 1471-2407 DI - 1471-2407-12-189 DO - https://dx.doi.org/10.1186/1471-2407-12-189 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 22632109 [pubmed] ID - 1471-2407-12-189 [pii] ID - 10.1186/1471-2407-12-189 [doi] ID - PMC3515414 [pmc] PP - epublish PH - 2012/04/05 [received] PH - 2012/05/15 [accepted] LG - English EP - 20120525 DP - 2012 May 25 DC - 20121210 EZ - 2012/05/29 06:00 DA - 2013/05/25 06:00 DT - 2012/05/29 06:00 YR - 2012 ED - 20130523 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22632109 <317. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23230868 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tewari AK AU - Ali A AU - Ghareeb G AU - Ludwig W AU - Metgud S AU - Theckumparampil N AU - Takenaka A AU - Chugtai B AU - Shrivastava A AU - Kaplan SA AU - Leung R AU - Paryani R AU - Grushow S AU - Durand M AU - Peyser A AU - Chopra S AU - Harneja N AU - Lee RK AU - Herman M AU - Robinson B AU - Shevchuck MM FA - Tewari, Ashutosh K FA - Ali, Adnan FA - Ghareeb, George FA - Ludwig, Wesley FA - Metgud, Sheela FA - Theckumparampil, Nithin FA - Takenaka, Atsushi FA - Chugtai, Bilal FA - Shrivastava, Abhishek FA - Kaplan, Steve A FA - Leung, Robert FA - Paryani, Rahul FA - Grushow, Siobhan FA - Durand, Matthieu FA - Peyser, Alexandra FA - Chopra, Sameer FA - Harneja, Niyati FA - Lee, Richard K FA - Herman, Michael FA - Robinson, Brian FA - Shevchuck, Maria M IN - Tewari, Ashutosh K. Department of Urology, Weill Cornell Medical College of Cornell University, New York, NY, USA. akt2002@med.cornell.edu TI - Improving time to continence after robot-assisted laparoscopic prostatectomy: augmentation of the total anatomic reconstruction technique by adding dynamic detrusor cuff trigonoplasty and suprapubic tube placement. SO - Journal of Endourology. 26(12):1546-52, 2012 Dec AS - J Endourol. 26(12):1546-52, 2012 Dec NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Dissection MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy MH - Male MH - *Muscles/su [Surgery] MH - Pilot Projects MH - Postoperative Care MH - Postoperative Complications/et [Etiology] MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - Reconstructive Surgical Procedures/ae [Adverse Effects] MH - *Reconstructive Surgical Procedures/mt [Methods] MH - *Robotics MH - Time Factors MH - *Urinary Catheterization MH - *Urinary Incontinence/et [Etiology] AB - After robot-assisted laparoscopic prostatectomy, total anatomic reconstruction (TR) with the additions of a circumapical urethral dissection, a dynamic detrusor cuff trigonoplasty, and placement of a suprapubic catheter was performed in 49 patients from June to July 2012. Continence at 6 weeks after catheter removal was assessed for an initial group of 23 patients, and also at 2 weeks in an additional 26 patients who most recently had undergone surgery. Follow-up appointments and telephone interviews were used to assess pad use and continence. Of the initial 23 patients receiving the modified TR, 60.9% had 0 pad use at 6 weeks. By 2 weeks, 65.4% of the most recent 26 patients operated on achieved continence with 0-1 pad use. Preservation and reconstruction of the pelvic floor and supporting bladder structures leads to an earlier return of continence. These key steps need to be validated and confirmed in larger and randomized trials. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2012.0544 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 23230868 [pubmed] ID - 10.1089/end.2012.0544 [doi] PP - ppublish LG - English DP - 2012 Dec DC - 20121212 EZ - 2012/12/13 06:00 DA - 2013/05/17 06:00 DT - 2012/12/13 06:00 YR - 2012 ED - 20130515 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=23230868 <318. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22800183 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - van der Poel HG AU - de Blok W AU - Tillier C AU - van Muilekom E FA - van der Poel, Henk G FA - de Blok, Willem FA - Tillier, Corinne FA - van Muilekom, Erik IN - van der Poel, Henk G. Department of Urology, Netherlands Cancer Institute, Amsterdam, The Netherlands. h.vd.poel@nki.nl TI - Robot-assisted laparoscopic prostatectomy: nodal dissection results during the first 440 cases by two surgeons. SO - Journal of Endourology. 26(12):1618-24, 2012 Dec AS - J Endourol. 26(12):1618-24, 2012 Dec NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy MH - Learning Curve MH - Logistic Models MH - Lymph Node Excision/ae [Adverse Effects] MH - *Lymph Node Excision/mt [Methods] MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Operative Time MH - *Physicians MH - Postoperative Complications/et [Etiology] MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/su [Surgery] MH - Risk Factors MH - *Robotics AB - BACKGROUND: Although many studies address the learning curve for robot-assisted laparoscopic prostatectomy (RALP), little is known concerning the results for pelvic lymph node dissection (LND) during RALP. AB - PATIENTS AND METHODS: Between 2006 and 2011, two surgeons performed 904 RALP procedures. LND was performed in 440 (48.6%) cases based on the European Association of Urology guidelines. Both surgeons had extensive experience with open LND for both prostate and bladder cancer. Clinical data were prospectively recorded into an online database. Complications were reported using the Clavien-Dindo system and documented prospectively. AB - RESULTS: For both surgeons, the operative time for LND decreased over time during the first 150 LND procedures. After that, a mean plateau of operative time of 49 minutes for LND was reached. Nodal yield increased from a mean of 10 nodes for the first 50 cases to 14 for cases 351 to 400. The percentage of positive nodes increased significantly in these intervals from 4% to 23.1% (P<0.001, Mann Whitney U test). Overall complications by grade were not significantly different between RALP with or without LND. In 440 LND cases, 5 (1.5%) grade IIIb complications occurred. All were infection related with bowel perforation in one. Symptomatic lymphoceles necessitating drainage were present in five (1.5%) men. Thromboembolic events (0% vs 1.5%) and anastomosis dehiscence (0.2% vs 1.1%) were more common in men with LND. During the learning curve, the incidence of Clavien grade I and II but not grade III and IV complications decreased. AB - CONCLUSION: An improvement pattern for LND during RALP is observed for operative time, nodal yield node positivity rate, and complication rate during the first 400 cases of LND. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2012.0360 PT - Clinical Trial PT - Journal Article ID - 22800183 [pubmed] ID - 10.1089/end.2012.0360 [doi] PP - ppublish LG - English EP - 20120925 DP - 2012 Dec DC - 20121212 EZ - 2012/07/18 06:00 DA - 2013/05/17 06:00 DT - 2012/07/18 06:00 YR - 2012 ED - 20130515 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22800183 <319. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21781338 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Waldorff FB AU - Siersma V AU - Ertmann R AU - Kousgaard MB AU - Nielsen AS AU - Felding P AU - Mosbaek N AU - Hjortso E AU - Reventlow S FA - Waldorff, Frans B FA - Siersma, Volkert FA - Ertmann, Ruth FA - Kousgaard, Marius Brostrom FA - Nielsen, Anette Sonne FA - Felding, Peter FA - Mosbaek, Niels FA - Hjortso, Else FA - Reventlow, Susanne IN - Waldorff, Frans B. The Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark. fransw@sund.ku.dk TI - The efficacy of computer reminders on external quality assessment for point-of-care testing in Danish general practice: rationale and methodology for two randomized trials. SO - Implementation Science. 6:79, 2011 Jul 23 AS - Implement Sci. 6:79, 2011 Jul 23 NJ - Implementation science : IS PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101258411 IO - Implement Sci PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158743 SB - Index Medicus CP - England MH - Cross-Over Studies MH - Denmark MH - Female MH - *General Practice MH - *Guideline Adherence MH - Humans MH - Male MH - *Medical Records Systems, Computerized MH - Middle Aged MH - *Point-of-Care Systems MH - Practice Guidelines as Topic MH - *Quality Control MH - *Reminder Systems AB - BACKGROUND: Point-of-care testing (POCT) is increasingly being used in general practice to assist general practitioners (GPs) in their management of patients with diseases. However, low adherence to quality guidelines in terms of split test procedures has been observed among GPs in parts of the Capital Region in Denmark. Computer reminders embedded in GPs electronic medical records (ComRem) may facilitate improved quality control behaviour, but more research is needed to identify what types of reminders work and when. The overall aim of this study is to evaluate the efficacy of ComRem to improve GPs adherence to quality guidelines. This article describes the rationale and methods of the study that constitute this research project. AB - METHODS/DESIGN: The study is conducted as two randomised controlled trials (RCTs) among general practices in two districts of the Capital Region in Denmark. These districts contain a total of 739 GPs in 567 practices with a total of 1.1 million patients allocated to practice lists. In the first RCT (RCT A), ComRem is compared to postal reminder letters. In the second RCT (RCT B), ComRem is compared to usual activities (no reminders) with a crossover approach. In both of these studies, outcomes are measured by the number of split tests received by the laboratory. AB - CONCLUSIONS: This study will contribute to knowledge on the efficacy of ComRem in primary care. Because the study does not explore GPs' perceptions and experiences with regard to ComRem, we will subsequently conduct a qualitative survey focusing on these aspects. AB - TRIAL REGISTRATIONS: Study A: ClinicalTrials.gov identifier: NCT01152151Study B: ClinicalTrials.gov identifier: NCT01152177. NT - Original DateCompleted: 20111110 ES - 1748-5908 IL - 1748-5908 DI - 1748-5908-6-79 DO - https://dx.doi.org/10.1186/1748-5908-6-79 PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 21781338 [pubmed] ID - 1748-5908-6-79 [pii] ID - 10.1186/1748-5908-6-79 [doi] ID - PMC3158743 [pmc] PP - epublish PH - 2011/02/14 [received] PH - 2011/07/23 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01152151 SA - ClinicalTrials.gov/NCT01152177 SL - https://clinicaltrials.gov/search/term=NCT01152151 SL - https://clinicaltrials.gov/search/term=NCT01152177 LG - English EP - 20110723 DP - 2011 Jul 23 DC - 20110822 EZ - 2011/07/26 06:00 DA - 2011/07/26 06:01 DT - 2011/07/26 06:00 YR - 2011 ED - 20130405 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=21781338 <320. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21781338 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Waldorff FB AU - Siersma V AU - Ertmann R AU - Kousgaard MB AU - Nielsen AS AU - Felding P AU - Mosbaek N AU - Hjortso E AU - Reventlow S FA - Waldorff, Frans B FA - Siersma, Volkert FA - Ertmann, Ruth FA - Kousgaard, Marius Brostrom FA - Nielsen, Anette Sonne FA - Felding, Peter FA - Mosbaek, Niels FA - Hjortso, Else FA - Reventlow, Susanne IN - Waldorff, Frans B. The Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark. fransw@sund.ku.dk TI - The efficacy of computer reminders on external quality assessment for point-of-care testing in Danish general practice: rationale and methodology for two randomized trials. SO - Implementation Science. 6:79, 2011 Jul 23 AS - Implement Sci. 6:79, 2011 Jul 23 NJ - Implementation science : IS PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101258411 IO - Implement Sci PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158743 SB - Index Medicus CP - England MH - Cross-Over Studies MH - Denmark MH - Female MH - *General Practice MH - *Guideline Adherence MH - Humans MH - Male MH - *Medical Records Systems, Computerized MH - Middle Aged MH - *Point-of-Care Systems MH - Practice Guidelines as Topic MH - *Quality Control MH - *Reminder Systems AB - BACKGROUND: Point-of-care testing (POCT) is increasingly being used in general practice to assist general practitioners (GPs) in their management of patients with diseases. However, low adherence to quality guidelines in terms of split test procedures has been observed among GPs in parts of the Capital Region in Denmark. Computer reminders embedded in GPs electronic medical records (ComRem) may facilitate improved quality control behaviour, but more research is needed to identify what types of reminders work and when. The overall aim of this study is to evaluate the efficacy of ComRem to improve GPs adherence to quality guidelines. This article describes the rationale and methods of the study that constitute this research project. AB - METHODS/DESIGN: The study is conducted as two randomised controlled trials (RCTs) among general practices in two districts of the Capital Region in Denmark. These districts contain a total of 739 GPs in 567 practices with a total of 1.1 million patients allocated to practice lists. In the first RCT (RCT A), ComRem is compared to postal reminder letters. In the second RCT (RCT B), ComRem is compared to usual activities (no reminders) with a crossover approach. In both of these studies, outcomes are measured by the number of split tests received by the laboratory. AB - CONCLUSIONS: This study will contribute to knowledge on the efficacy of ComRem in primary care. Because the study does not explore GPs' perceptions and experiences with regard to ComRem, we will subsequently conduct a qualitative survey focusing on these aspects. AB - TRIAL REGISTRATIONS: Study A: ClinicalTrials.gov identifier: NCT01152151Study B: ClinicalTrials.gov identifier: NCT01152177. NT - Original DateCompleted: 20111110 ES - 1748-5908 IL - 1748-5908 DI - 1748-5908-6-79 DO - https://dx.doi.org/10.1186/1748-5908-6-79 PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 21781338 [pubmed] ID - 1748-5908-6-79 [pii] ID - 10.1186/1748-5908-6-79 [doi] ID - PMC3158743 [pmc] PP - epublish PH - 2011/02/14 [received] PH - 2011/07/23 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01152151 SA - ClinicalTrials.gov/NCT01152177 SA - ClinicalTrials.gov/NCT01152151 SA - ClinicalTrials.gov/NCT01152177 SL - https://clinicaltrials.gov/search/term=NCT01152151 SL - https://clinicaltrials.gov/search/term=NCT01152177 SL - https://clinicaltrials.gov/search/term=NCT01152151 SL - https://clinicaltrials.gov/search/term=NCT01152177 LG - English EP - 20110723 DP - 2011 Jul 23 DC - 20110822 EZ - 2011/07/26 06:00 DA - 2011/07/26 06:01 DT - 2011/07/26 06:00 YR - 2011 ED - 20130405 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21781338 <321. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22170893 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Jacobs BL AU - Montgomery JS AU - Dunn RL AU - Weizer AZ AU - Miller DC AU - Wood DP AU - Wolf JS Jr AU - Zhang Y AU - Wei JT AU - Hollenbeck BK FA - Jacobs, Bruce L FA - Montgomery, Jeffrey S FA - Dunn, Rodney L FA - Weizer, Alon Z FA - Miller, David C FA - Wood, David P FA - Wolf, J Stuart Jr FA - Zhang, Yun FA - Wei, John T FA - Hollenbeck, Brent K IN - Jacobs, Bruce L. Department of Urology, University of Michigan, Ann Arbor, MI 48109-2800, USA. brucejac@med.umich.edu TI - A comparison of extraperitoneal and intraperitoneal approaches for robotic prostatectomy. SO - Surgical Innovation. 19(3):268-74, 2012 Sep AS - Surg Innov. 19(3):268-74, 2012 Sep NJ - Surgical innovation PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101233809 IO - Surg Innov PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391538 OI - Source: NLM. NIHMS366628 SB - Index Medicus CP - United States MH - Aged MH - Chi-Square Distribution MH - Humans MH - Male MH - Middle Aged MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotics/mt [Methods] MH - Surveys and Questionnaires MH - Treatment Outcome AB - OBJECTIVES: This study compared oncologic and health-related quality-of-life outcomes among patients undergoing intraperitoneal or extraperitoneal robotic prostatectomy. AB - METHODS: Of 215 patients undergoing robotic prostatectomy, the approach was intraperitoneal in 48 and extraperitoneal in 167. Cancer control was evaluated using margin status. Recovery after surgery and functional health was assessed using the convalescence and recovery evaluation and expanded prostate cancer index composite questionnaires, respectively. AB - RESULTS: Positive surgical margin rates were similar between approaches (14% extraperitoneal, 10% intraperitoneal; P = .63). Functional outcomes were slightly improved for those with the extraperitoneal approach (i.e., higher urinary irritation/obstruction scores at 3 months). The extraperitoneal group demonstrated higher activity (91.8 vs 83.3, P = .03) and cognitive scores (94.9 vs. 91.7, P = .04) at 6 weeks as well as higher gastrointestinal scores at 2 weeks (94.2 vs. 90.8, P = .05). AB - CONCLUSIONS: These data support efforts to broaden the adoption of the extraperitoneal approach for robotic prostatectomy. ES - 1553-3514 IL - 1553-3506 DI - 1553350611429028 DO - https://dx.doi.org/10.1177/1553350611429028 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Research Support, N.I.H., Extramural ID - 22170893 [pubmed] ID - 1553350611429028 [pii] ID - 10.1177/1553350611429028 [doi] ID - PMC3391538 [pmc] ID - NIHMS366628 [mid] PP - ppublish GI - No: T32 DK007782 Organization: (DK) *NIDDK NIH HHS* Country: United States No: T32 DK007782-11 Organization: (DK) *NIDDK NIH HHS* Country: United States No: 5 T32 DK007782-12 Organization: (DK) *NIDDK NIH HHS* Country: United States LG - English EP - 20111213 DP - 2012 Sep DC - 20120914 EZ - 2011/12/16 06:00 DA - 2013/03/30 06:00 DT - 2011/12/16 06:00 YR - 2012 ED - 20130329 RD - 20161122 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22170893 <322. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23074122 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Yoo YC AU - Bai SJ AU - Lee KY AU - Shin S AU - Choi EK AU - Lee JW FA - Yoo, Young-Chul FA - Bai, Sun-Joon FA - Lee, Ki-Young FA - Shin, Seokyung FA - Choi, Eun Kyeong FA - Lee, Jong Whax IN - Yoo, Young-Chul. Division of Anesthesiology and Pain Medicine, Cardiovascular Hospital, Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, Korea. TI - Total intravenous anesthesia with propofol reduces postoperative nausea and vomiting in patients undergoing robot-assisted laparoscopic radical prostatectomy: a prospective randomized trial. SO - Yonsei Medical Journal. 53(6):1197-202, 2012 Nov 01 AS - Yonsei Med J. 53(6):1197-202, 2012 Nov 01 NJ - Yonsei medical journal PI - Journal available in: Print PI - Citation processed from: Internet JC - xrr, 0414003 IO - Yonsei Med. J. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481386 SB - Index Medicus CP - Korea (South) MH - Aged MH - *Anesthesia, Intravenous/mt [Methods] MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - *Postoperative Nausea and Vomiting/pc [Prevention & Control] MH - Propofol/ad [Administration & Dosage] MH - *Propofol/tu [Therapeutic Use] MH - *Prostatectomy/mt [Methods] MH - *Vomiting/pc [Prevention & Control] AB - PURPOSE: We investigated the effect of total intravenous anesthesia (TIVA) with propofol on postoperative nausea and vomiting (PONV) after robot-assisted laparoscopic radical prostatectomy (RLRP) in patients at low risk of developing PONV, in comparison to balanced anesthesia with desflurane. AB - MATERIALS AND METHODS: Sixty two patients were randomly assigned to the Des or TIVA group. Propofol and remifentanil were used for induction of anesthesia in both groups and for maintenance of the anesthesia in the TIVA group. In the Des group, anesthesia was maintained with desflurane and remifentanil. In both groups, postoperative pain was controlled using fentanyl-based intravenous patient controlled analgesia, and ramosetron 0.3 mg was administered at the end of surgery. The incidence of PONV, severity of nausea and pain, and requirements of rescue antiemetics and analgesics were recorded. AB - RESULTS: The incidence of nausea in the post-anesthetic care unit was 22.6% in the Des group and 6.5% in the TIVA (p=0.001) group. The incidence of nausea at postoperative 1-6 hours was 54.8% in the Des group and 16.1% in the TIVA group (p=0.001). At postoperative 6-48 hours, there were no significant differences in the incidence of nausea between groups. AB - CONCLUSION: In order to prevent PONV after RLRP in the early postoperative period, anesthesia using TIVA with propofol is required regardless of patient-related risk factors. RN - YI7VU623SF (Propofol) ES - 1976-2437 IL - 0513-5796 DI - 2012111197 DO - https://dx.doi.org/10.3349/ymj.2012.53.6.1197 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 23074122 [pubmed] ID - 2012111197 [pii] ID - 10.3349/ymj.2012.53.6.1197 [doi] ID - PMC3481386 [pmc] PP - ppublish LG - English DP - 2012 Nov 01 DC - 20121017 EZ - 2012/10/18 06:00 DA - 2013/03/15 06:00 DT - 2012/10/18 06:00 YR - 2012 ED - 20130314 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=23074122 <323. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23074122 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Yoo YC AU - Bai SJ AU - Lee KY AU - Shin S AU - Choi EK AU - Lee JW FA - Yoo, Young-Chul FA - Bai, Sun-Joon FA - Lee, Ki-Young FA - Shin, Seokyung FA - Choi, Eun Kyeong FA - Lee, Jong Whax IN - Yoo, Young-Chul. Division of Anesthesiology and Pain Medicine, Cardiovascular Hospital, Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, Korea. TI - Total intravenous anesthesia with propofol reduces postoperative nausea and vomiting in patients undergoing robot-assisted laparoscopic radical prostatectomy: a prospective randomized trial. SO - Yonsei Medical Journal. 53(6):1197-202, 2012 Nov 01 AS - Yonsei Med J. 53(6):1197-202, 2012 Nov 01 NJ - Yonsei medical journal PI - Journal available in: Print PI - Citation processed from: Internet JC - xrr, 0414003 IO - Yonsei Med. J. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481386 SB - Index Medicus CP - Korea (South) MH - Aged MH - *Anesthesia, Intravenous/mt [Methods] MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - *Postoperative Nausea and Vomiting/pc [Prevention & Control] MH - Propofol/ad [Administration & Dosage] MH - *Propofol/tu [Therapeutic Use] MH - *Prostatectomy/mt [Methods] MH - *Vomiting/pc [Prevention & Control] AB - PURPOSE: We investigated the effect of total intravenous anesthesia (TIVA) with propofol on postoperative nausea and vomiting (PONV) after robot-assisted laparoscopic radical prostatectomy (RLRP) in patients at low risk of developing PONV, in comparison to balanced anesthesia with desflurane. AB - MATERIALS AND METHODS: Sixty two patients were randomly assigned to the Des or TIVA group. Propofol and remifentanil were used for induction of anesthesia in both groups and for maintenance of the anesthesia in the TIVA group. In the Des group, anesthesia was maintained with desflurane and remifentanil. In both groups, postoperative pain was controlled using fentanyl-based intravenous patient controlled analgesia, and ramosetron 0.3 mg was administered at the end of surgery. The incidence of PONV, severity of nausea and pain, and requirements of rescue antiemetics and analgesics were recorded. AB - RESULTS: The incidence of nausea in the post-anesthetic care unit was 22.6% in the Des group and 6.5% in the TIVA (p=0.001) group. The incidence of nausea at postoperative 1-6 hours was 54.8% in the Des group and 16.1% in the TIVA group (p=0.001). At postoperative 6-48 hours, there were no significant differences in the incidence of nausea between groups. AB - CONCLUSION: In order to prevent PONV after RLRP in the early postoperative period, anesthesia using TIVA with propofol is required regardless of patient-related risk factors. RN - YI7VU623SF (Propofol) ES - 1976-2437 IL - 0513-5796 DI - 2012111197 DO - https://dx.doi.org/10.3349/ymj.2012.53.6.1197 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 23074122 [pubmed] ID - 2012111197 [pii] ID - 10.3349/ymj.2012.53.6.1197 [doi] ID - PMC3481386 [pmc] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01402622 SL - https://clinicaltrials.gov/search/term=NCT01402622 LG - English DP - 2012 Nov 01 DC - 20121017 EZ - 2012/10/18 06:00 DA - 2013/03/15 06:00 DT - 2012/10/18 06:00 YR - 2012 ED - 20130314 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=23074122 <324. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23247974 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - More YI AU - Tsue TT AU - Girod DA AU - Harbison J AU - Sykes KJ AU - Williams C AU - Shnayder Y FA - More, Yogesh I FA - Tsue, Terance T FA - Girod, Douglas A FA - Harbison, John FA - Sykes, Kevin J FA - Williams, Carson FA - Shnayder, Yelizaveta IN - More, Yogesh I. Department of Otolaryngology, Kansas University Medical Center, Kansas City, KS 66103, USA. dryogeshmore@gmail.com TI - Functional swallowing outcomes following transoral robotic surgery vs primary chemoradiotherapy in patients with advanced-stage oropharynx and supraglottis cancers.[Erratum appears in JAMA Otolaryngol Head Neck Surg. 2013 Mar;139(3):292] SO - JAMA Otolaryngology-- Head & Neck Surgery. 139(1):43-8, 2013 Jan AS - JAMA Otolaryngol Head Neck Surg. 139(1):43-8, 2013 Jan NJ - JAMA otolaryngology-- head & neck surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 101589542 IO - JAMA Otolaryngol Head Neck Surg SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Biopsy MH - *Chemoradiotherapy MH - Chi-Square Distribution MH - Combined Modality Therapy MH - *Deglutition Disorders/pp [Physiopathology] MH - Female MH - Follow-Up Studies MH - Glottis/pa [Pathology] MH - Humans MH - Male MH - Middle Aged MH - Neoplasm Staging MH - Oropharyngeal Neoplasms/pa [Pathology] MH - Oropharyngeal Neoplasms/pp [Physiopathology] MH - *Oropharyngeal Neoplasms/th [Therapy] MH - *Postoperative Complications/pp [Physiopathology] MH - Prospective Studies MH - Recovery of Function MH - *Robotics MH - Statistics, Nonparametric AB - OBJECTIVES: To evaluate functional swallowing outcomes in patients undergoing transoral robotic surgery vs primary chemoradiotherapy for the management of advanced-stage oropharynx and supraglottis cancers. AB - DESIGN: Prospective nonrandomized clinical trial. AB - SETTING: Academic research. AB - PATIENTS: We studied 40 patients with stage III or stage IVA oropharynx and supraglottis squamous cell carcinoma. Group 1 comprised 20 patients who received transoral robotic surgery with adjuvant therapy, while group 2 comprised 20 patients whose disease was managed by primary chemoradiotherapy. AB - MAIN OUTCOME MEASURES: Patients completed the M. D. Anderson Dysphagia Inventory (MDADI) before treatment and then at follow-up visits at 3, 6, and 12 months. The MDADI scores were analyzed and compared. AB - RESULTS: The median follow-up period for both groups was 14 months (range, 12-16 months). When comparing the median MDADI scores between group 1 and group 2, we found no statistically significant differences before treatment or at the 3-month follow-up visit. However, this difference was significant at the posttreatment visits at 6 months (P = .004) and 12 months (P = .006), where group 1 had better swallowing MDADI scores. We also found significant differences in swallowing MDADI scores between the groups at the 6-month posttreatment visit for patients with T1, T2, and T3 disease and at the 12-month follow-up visit for patients with T2 and T3 disease, where group 1 had significantly better MDADI scores. Comparing tumor subsites, group 1 fared significantly better at the follow-up visits at 6 months (P = .02) and 12 months (P = .04) for patients with primary tumor at the tonsil. Compared with group 2, group 1 patients having base of tongue cancers exhibited significantly better swallowing MDADI scores at the 6-month follow-up visit (P = .02), and group 1 patients having lateral oropharynx disease had significantly better swallowing MDADI scores at the 12-month follow-up visit (P = .04). AB - CONCLUSION: Advanced-stage oropharynx and supraglottis cancers managed by transoral robotic surgery with adjuvant therapy resulted in significantly better swallowing MDADI outcomes at the follow-up visits at 6 and 12 months compared with tumors treated by primary chemoradiotherapy. ES - 2168-619X IL - 2168-6181 DI - 1485601 DO - https://dx.doi.org/10.1001/jamaoto.2013.1074 PT - Clinical Trial PT - Journal Article ID - 23247974 [pubmed] ID - 1485601 [pii] ID - 10.1001/jamaoto.2013.1074 [doi] PP - ppublish LG - English DP - 2013 Jan DC - 20130220 EZ - 2012/12/19 06:00 DA - 2013/03/13 06:00 DT - 2012/12/19 06:00 YR - 2013 ED - 20130312 RD - 20130514 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=23247974 <325. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21665396 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Jodocy D AU - Abbrederis S AU - Graziadei IW AU - Vogel W AU - Pachinger O AU - Feuchtner GM AU - Jaschke W AU - Friedrich G FA - Jodocy, Daniel FA - Abbrederis, Susanne FA - Graziadei, Ivo W FA - Vogel, Wolfgang FA - Pachinger, Otmar FA - Feuchtner, Gudrun M FA - Jaschke, Werner FA - Friedrich, Guy IN - Jodocy, Daniel. Department of Internal Medicine III (Cardiology), Medical University of Innsbruck, Anichstrase 35, A-6020 Innsbruck, Austria. daniel.jodocy@klinikum-minden.de TI - Coronary computer tomographic angiography for preoperative risk stratification in patients undergoing liver transplantation. SO - European Journal of Radiology. 81(9):2260-4, 2012 Sep AS - Eur J Radiol. 81(9):2260-4, 2012 Sep NJ - European journal of radiology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - em6, 8106411 IO - Eur J Radiol SB - Index Medicus CP - Ireland MH - Adult MH - Aged MH - Austria/ep [Epidemiology] MH - *Coronary Angiography/sn [Statistics & Numerical Data] MH - *Coronary Artery Disease/dg [Diagnostic Imaging] MH - *Coronary Artery Disease/ep [Epidemiology] MH - Female MH - Humans MH - *Liver Transplantation/dg [Diagnostic Imaging] MH - *Liver Transplantation/sn [Statistics & Numerical Data] MH - Male MH - Middle Aged MH - *Postoperative Complications/dg [Diagnostic Imaging] MH - *Postoperative Complications/ep [Epidemiology] MH - Preoperative Care/mt [Methods] MH - Preoperative Care/sn [Statistics & Numerical Data] MH - Prevalence MH - Prognosis MH - Risk Assessment MH - Tomography, X-Ray Computed MH - Treatment Outcome AB - The assessment of the cardiovascular risk profile in patients with end-stage liver disease is essential prior to liver transplantation (LT) as cardiovascular diseases are major causes of morbidity and mortality in the posttransplant course. The aim of this study was to evaluate the accuracy of a 64-slice coronary computed tomographic angiography (CTA) and coronary calcium scoring (CCS) to predict the postoperative cardiovascular risk of patients assessed for LT. In this single center, observational study we included 54 consecutive patients who were assessed for LT and consequently transplanted. Twenty-four patients (44%) presented with a high CCS above 300 and/or a significant stenosis (>50% percent narrowing due to stenotic plaques) and were further referred to coronary angiography. Three of these patients had a more than 70% LAD stenosis with subsequent angioplasty (n=1) or conservative therapy (n=2). The other patients showed only diffuse CAD without significant stenosis. The remaining 30 patients with normal CTA findings were listed for LT without further tests. None of the 54 patients developed cardiovascular events peri- and postoperatively. This study indicated that CTA combined with CCS is a useful non-invasive imaging technique for pre-LT assessment of coronary artery disease and safe tool in the risk assessment of peri- and postoperative cardiovascular events in patients undergoing LT. AB - Copyright © 2011 Elsevier Ireland Ltd. All rights reserved. ES - 1872-7727 IL - 0720-048X DI - S0720-048X(11)00486-4 DO - https://dx.doi.org/10.1016/j.ejrad.2011.05.009 PT - Clinical Trial PT - Journal Article ID - 21665396 [pubmed] ID - S0720-048X(11)00486-4 [pii] ID - 10.1016/j.ejrad.2011.05.009 [doi] PP - ppublish PH - 2010/12/27 [received] PH - 2011/04/27 [revised] PH - 2011/05/09 [accepted] LG - English EP - 20110612 DP - 2012 Sep DC - 20120810 EZ - 2011/06/14 06:00 DA - 2013/01/15 06:00 DT - 2011/06/15 06:00 YR - 2012 ED - 20130114 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21665396 <326. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22921704 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tanagho YS AU - Bhayani SB AU - Sandhu GS AU - Vaughn NP AU - Nepple KG AU - Figenshau RS FA - Tanagho, Youssef S FA - Bhayani, Sam B FA - Sandhu, Gurdarshan S FA - Vaughn, Nicholas P FA - Nepple, Kenneth G FA - Figenshau, R Sherburne IN - Tanagho, Youssef S. Division of Urologic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA. TI - Renal functional and perioperative outcomes of off-clamp versus clamped robot-assisted partial nephrectomy: matched cohort study. CM - Comment in: Urology. 2012 Oct;80(4):843; author reply 843-4; PMID: 22921706 SO - Urology. 80(4):838-43, 2012 Oct AS - Urology. 80(4):838-43, 2012 Oct NJ - Urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142222 OI - Source: NLM. NIHMS545262 SB - Index Medicus CP - United States MH - Aged MH - Blood Loss, Surgical MH - Blood Transfusion MH - *Carcinoma, Renal Cell/pp [Physiopathology] MH - *Carcinoma, Renal Cell/su [Surgery] MH - Case-Control Studies MH - Constriction MH - Follow-Up Studies MH - Glomerular Filtration Rate MH - Humans MH - *Kidney Neoplasms/pp [Physiopathology] MH - *Kidney Neoplasms/su [Surgery] MH - Middle Aged MH - Neoplasm, Residual MH - Nephrectomy/ae [Adverse Effects] MH - *Nephrectomy/mt [Methods] MH - Retrospective Studies MH - Robotics MH - Time Factors AB - OBJECTIVE: To evaluate the potential benefit of performing off-clamp robot-assisted partial nephrectomy as it relates to renal functional outcomes, while assessing the safety profile of this unconventional surgical approach. AB - METHODS: Twenty-nine patients who underwent off-clamp robot-assisted partial nephrectomy for suspected renal cell carcinoma at Washington University between March 2008 and September 2011 (group 1) were matched to 29 patients with identical nephrometry scores and comparable baseline renal function who underwent robot-assisted partial nephrectomy with hilar clamping during the same period (group 2). The matched cohorts' perioperative and renal functional outcomes were compared at a mean 9-month follow-up. AB - RESULTS: Mean estimated blood loss was 146.4 mL in group 1, versus 103.9 mL in group 2 (P = .039). Mean hilar clamp time was 0 minutes in group 1 and 14.7 minutes in group 2. No perioperative complications were encountered in group 1; 1 Clavien-2 complication (3.4%) occurred in group 2 (P = 1.000). At 9-month follow-up, mean estimated glomerular filtration rate in group 1 was 79.9 versus 84.8 mL/min/1.73 m(2) preoperatively (P = .013); mean estimated glomerular filtration rate in group 2 was 74.1 versus 85.8 mL/min/1.73 m(2) preoperatively (P < .001). Hence, estimated glomerular filtration rate declined by a mean of 4.9 mL/min/1.73 m(2) in group 1 versus 11.7 mL/min/1.73 m(2) in group 2 (P = .033). AB - CONCLUSION: Off-clamp robot-assisted partial nephrectomy is associated with a favorable morbidity profile and relatively greater renal functional preservation compared to clamped robot-assisted partial nephrectomy. Nevertheless, the benefit is small in renal functional terms and may have very limited clinical relevance. AB - Copyright © 2012 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(12)00685-1 DO - https://dx.doi.org/10.1016/j.urology.2012.04.074 PT - Journal Article ID - 22921704 [pubmed] ID - S0090-4295(12)00685-1 [pii] ID - 10.1016/j.urology.2012.04.074 [doi] ID - PMC4142222 [pmc] ID - NIHMS545262 [mid] PP - ppublish PH - 2012/02/25 [received] PH - 2012/04/12 [revised] PH - 2012/04/13 [accepted] GI - No: KM1 CA156708 Organization: (CA) *NCI NIH HHS* Country: United States LG - English EP - 20120822 DP - 2012 Oct DC - 20121001 EZ - 2012/08/28 06:00 DA - 2013/01/01 06:00 DT - 2012/08/28 06:00 YR - 2012 ED - 20121231 RD - 20161025 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22921704 <327. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22963354 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Parekh S AU - Vandelanotte C AU - King D AU - Boyle FM FA - Parekh, Sanjoti FA - Vandelanotte, Corneel FA - King, David FA - Boyle, Frances M IN - Parekh, Sanjoti. School of Population Health & Healthy Communities Research Centre, The University of Queensland Herston, Queensland 4006, Australia. s.parekh@uq.edu.au TI - Improving diet, physical activity and other lifestyle behaviours using computer-tailored advice in general practice: a randomised controlled trial. SO - International Journal of Behavioral Nutrition & Physical Activity. 9:108, 2012 Sep 11 AS - Int. j. behav. nutr. phys. act.. 9:108, 2012 Sep 11 NJ - The international journal of behavioral nutrition and physical activity PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101217089 IO - Int J Behav Nutr Phys Act PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479049 SB - Index Medicus CP - England MH - Australia/ep [Epidemiology] MH - Chronic Disease/ep [Epidemiology] MH - Chronic Disease/pc [Prevention & Control] MH - Diet/st [Standards] MH - *Diet MH - Feedback MH - Female MH - *General Practice/mt [Methods] MH - Health Behavior MH - *Health Promotion/mt [Methods] MH - Humans MH - *Life Style MH - Male MH - Middle Aged MH - Motor Activity MH - Obesity/ep [Epidemiology] MH - Obesity/pc [Prevention & Control] MH - Odds Ratio MH - *Risk Reduction Behavior MH - Surveys and Questionnaires AB - BACKGROUND: The adoption and maintenance of healthy behaviours is essential in the primary prevention of chronic non-communicable diseases. This study evaluated the effectiveness of a minimal intervention on multiple lifestyle factors such as diet, physical activity, smoking and alcohol, delivered through general practice, using computer-tailored feedback. AB - METHODS: Adult patients visiting 21 general practitioners in Brisbane, Australia, were surveyed about ten health behaviours that are risk factors for chronic, non-communicable diseases. Those who completed the self-administered baseline questionnaire entered a randomised controlled trial, with the intervention group receiving computer-tailored printed advice, targeting those health behaviours for which respondents were not meeting current recommendations. The primary outcome was change in summary lifestyle score (Prudence Score) and individual health behaviours at three months. A repeated measures analysis compared change in these outcomes in intervention and control groups after adjusting for age and education. AB - RESULTS: 2306 patients were randomised into the trial. 1711 (76%) returned the follow-up questionnaire at 3months. The Prudence Score (10 items) in the intervention group at baseline was 5.88, improving to 6.25 at 3months (improvement=0.37), compared with 5.84 to 5.96 (improvement=0.12) in the control group (F=13.3, p=0.01). The intervention group showed improvement in meeting recommendations for all individual health behaviours compared with the control group. However, these differences were significant only for fish intake (OR 1.37, 95% CI 1.11-1.68), salt intake (OR 1.19, 95% CI 1.05-1.38), and type of spread used (OR 1.28, 95% CI 1.06-1.51). AB - CONCLUSION: A minimal intervention using computer-tailored feedback to address multiple lifestyle behaviours can facilitate change and improve unhealthy behaviours. Although individual behaviour changes were modest, when implemented on a large scale through general practice, this intervention appears to be an effective and practical tool for population-wide primary prevention. AB - TRIAL REGISTRATION: The Australian New Zealand Clinical Trials Registry: ACTRN12611001213932. ES - 1479-5868 IL - 1479-5868 DI - 1479-5868-9-108 DO - https://dx.doi.org/10.1186/1479-5868-9-108 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 22963354 [pubmed] ID - 1479-5868-9-108 [pii] ID - 10.1186/1479-5868-9-108 [doi] ID - PMC3479049 [pmc] PP - epublish PH - 2011/12/09 [received] PH - 2012/08/30 [accepted] LG - English EP - 20120911 DP - 2012 Sep 11 DC - 20121024 EZ - 2012/09/12 06:00 DA - 2012/12/21 06:00 DT - 2012/09/12 06:00 YR - 2012 ED - 20121220 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22963354 <328. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22486229 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ouzaid I AU - Xylinas E AU - Ploussard G AU - Hoznek A AU - Vordos D AU - Abbou CC AU - de la Taille A AU - Salomon L FA - Ouzaid, Idir FA - Xylinas, Evanguelos FA - Ploussard, Guillaume FA - Hoznek, Andras FA - Vordos, Dimitri FA - Abbou, Claude-Clement FA - de la Taille, Alexandre FA - Salomon, Laurent IN - Ouzaid, Idir. Department of Urology, Henri Mondor Hospital, Paris-Est University, Creteil, France. idir.ouzaid@free.fr TI - Anastomotic stricture after minimally invasive radical prostatectomy: what should be expected from the Van Velthoven single-knot running suture?. SO - Journal of Endourology. 26(8):1020-5, 2012 Aug AS - J Endourol. 26(8):1020-5, 2012 Aug NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Anastomosis, Surgical MH - Constriction, Pathologic/et [Etiology] MH - Demography MH - Humans MH - Male MH - Middle Aged MH - *Minimally Invasive Surgical Procedures/ae [Adverse Effects] MH - Multivariate Analysis MH - Prostate/pa [Pathology] MH - Prostate/su [Surgery] MH - *Prostatectomy/ae [Adverse Effects] MH - Risk Factors MH - *Suture Techniques/ae [Adverse Effects] MH - *Sutures/ae [Adverse Effects] MH - Treatment Outcome MH - Urinary Bladder/pa [Pathology] AB - BACKGROUND AND PURPOSE: Patients with localized prostate cancer (PCa) who are treated by radical prostatectomy (RP) have a good overall survival rate. Their quality of life, however, can deteriorate because of the incidence of bladder neck contracture (BNC). Our aim was to evaluate the incidence and the risk factors of BNC after minimally invasive radical prostatectomy (MIRP) with a single-knot running suture also known as the Van Velthoven technique (VVT). AB - PATIENTS AND METHODS: From 2003 to 2010, 2115 patients underwent extraperitoneal, transperitoneal, or robot-assisted RP for localized PCa. A single-knot running suture according to the VVT was performed for the vesicourethral anastomosis. Follow-up was scheduled and standardized for all patients and recorded into a prospective database. BNC was defined by a reduction of the lumen that does not allow the passage of an 18F fibroscope. AB - RESULTS: Mean follow-up of the patients was 43 (6-144) months. Of all, 1342, 241, and 532 had extraperitoneal, transperitoneal, and robot-assisted prostatectomy, respectively. BNC was diagnosed in 30 (1.4%) patients. Among them, 78% had the diagnosis within the first year of follow-up. Previous transurethral resection of the prostate (TURP) and external beam radiotherapy were independent risk factors of BNC. AB - CONCLUSIONS: BNC incidence after MIRP using the single-knot running suture for the vesicourethral anastomosis is low. Previous TURP and external beam radiotherapy are identified as risk factors. This technique showed satisfying results regardless of the classic laparoscopic or robot-assisted approach. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2011.0650 PT - Clinical Trial PT - Journal Article ID - 22486229 [pubmed] ID - 10.1089/end.2011.0650 [doi] PP - ppublish LG - English EP - 20120508 DP - 2012 Aug DC - 20120808 EZ - 2012/04/11 06:00 DA - 2012/12/20 06:00 DT - 2012/04/11 06:00 YR - 2012 ED - 20121219 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22486229 <329. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22390682 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Philippou P AU - Waine E AU - Rowe E FA - Philippou, Prodromos FA - Waine, Elizabeth FA - Rowe, Edward IN - Philippou, Prodromos. Bristol Urological Institute, Southmead Hospital, North Bristol NHS Trust, Bristol, United Kingdom. brucemed@hotmail.com TI - Robot-assisted laparoscopic prostatectomy versus open: comparison of the learning curve of a single surgeon. SO - Journal of Endourology. 26(8):1002-8, 2012 Aug AS - J Endourol. 26(8):1002-8, 2012 Aug NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Humans MH - Intraoperative Care MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy/ed [Education] MH - *Learning Curve MH - Male MH - Middle Aged MH - Perioperative Care MH - *Physicians MH - Postoperative Complications/et [Etiology] MH - Prostate/pa [Pathology] MH - Prostate/su [Surgery] MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/ed [Education] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/su [Surgery] MH - *Robotics/ed [Education] MH - *Robotics/mt [Methods] MH - Time Factors AB - BACKGROUND AND PURPOSE: Because of the increased use of robot-assisted laparoscopic prostatectomy (RALP) for the management of localized prostate cancer, surgeons in training face the issues of developing skills in both open surgery and the robotic console. This study compares prospectively the safety and efficacy of the first 50 open radical retropubic prostatectomy (RRP) procedures and the first 50 RALP procedures, performed by the same surgeon in the same institution. AB - PATIENTS AND METHODS: The patients' baseline demographic, clinical, and oncologic parameters were prospectively recorded. The study end points included oncologic outcome, functional outcomes (at 3 months), and perioperative parameters. Complications were classified according to the modified Clavien system. AB - RESULTS: No statistically significant differences were noted between the two groups in terms of preoperative patient characteristics and oncologic parameters. The operative time and mean estimated blood loss were lower in the RALP group (P<0.001), but no statistically significant difference was noted in regard to transfusion rates (P=0.362). Mean hospital stay was lower in the RALP group (P<0.001). The minor (Clavien I+II) and major (Clavien III+IV) complication rates were comparable between the two groups. The overall positive margin (PSM) rates were 20% and 18% for RRP and RALP, respectively (P=0.799), while for pT(3) disease, the PSM rates were 26.1% and 22.2%% for RRP and RALP, respectively (P=0.53). The 3-month continence rates were 88% and 90% for RRP and RALP, respectively (P=0.749). For preoperatively potent patients, 3-month potency rates were comparable between the two groups (60.6% and 62.1% in the RRP and the RALP group, respectively, P=0.893). AB - CONCLUSION: The early learning curve for RALP appears safe and results in equivalent functional and oncologic outcome, when compared with the results of open surgery. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2011.0569 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 22390682 [pubmed] ID - 10.1089/end.2011.0569 [doi] PP - ppublish LG - English EP - 20120430 DP - 2012 Aug DC - 20120808 EZ - 2012/03/07 06:00 DA - 2012/12/20 06:00 DT - 2012/03/07 06:00 YR - 2012 ED - 20121219 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22390682 <330. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22260717 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Seideman CA AU - Tan YK AU - Faddegon S AU - Park SK AU - Best SL AU - Cadeddu JA AU - Olweny EO FA - Seideman, Casey A FA - Tan, Yung K FA - Faddegon, Stephen FA - Park, Samuel K FA - Best, Sara L FA - Cadeddu, Jeffrey A FA - Olweny, Ephrem O IN - Seideman, Casey A. Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9110, USA. TI - Robot-assisted laparoendoscopic single-site pyeloplasty: technique using the da Vinci Si robotic platform. CM - Comment in: J Endourol. 2012 Aug;26(8):974; PMID: 22486377 SO - Journal of Endourology. 26(8):971-4, 2012 Aug AS - J Endourol. 26(8):971-4, 2012 Aug NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Dissection MH - Humans MH - Laparoscopy/is [Instrumentation] MH - *Laparoscopy/mt [Methods] MH - Patient Positioning MH - Reconstructive Surgical Procedures/is [Instrumentation] MH - *Reconstructive Surgical Procedures/mt [Methods] MH - Robotics/is [Instrumentation] MH - *Robotics/mt [Methods] AB - Conventional laparoscopic dismembered pyeloplasty (LP) is an established alternative to open pyeloplasty given equivalent intermediate-term outcomes and decreased morbidity. Laparoendoscopic single-site (LESS) pyeloplasty has the potential to further decrease the morbidity of LP, while yielding superior cosmesis. It is, however, technically very challenging even with the use of an accessory port, largely because of the difficulty of intracorporeal suturing through a single umbilical incision. Application of the da Vinci robotic surgical platform to LESS pyeloplasty (R-LESS) has the potential to overcome these limitations. We describe our technique for R-LESS pyeloplasty using the da Vinci Si robot. We have found that use of the robotic system in conjunction with certain technique modifications helps to reduce the technical difficulty of LESS pyeloplasty and to shorten the physical learning curve associated with the procedure. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2011.0573 PT - Clinical Trial PT - Journal Article ID - 22260717 [pubmed] ID - 10.1089/end.2011.0573 [doi] PP - ppublish LG - English EP - 20120417 DP - 2012 Aug DC - 20120808 EZ - 2012/01/21 06:00 DA - 2012/12/20 06:00 DT - 2012/01/21 06:00 YR - 2012 ED - 20121219 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22260717 <331. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 23227452 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - PubMed-not-MEDLINE AU - Kunos CA AU - Brindle J AU - Waggoner S AU - Zanotti K AU - Resnick K AU - Fusco N AU - Adams R AU - Debernardo R FA - Kunos, Charles A FA - Brindle, James FA - Waggoner, Steven FA - Zanotti, Kristine FA - Resnick, Kimberly FA - Fusco, Nancy FA - Adams, Ramon FA - Debernardo, Robert IN - Kunos, Charles A. Department of Radiation Oncology, University Hospitals Case Medical Center and Case Western Reserve University, School of Medicine Cleveland, OH, USA. TI - Phase II Clinical Trial of Robotic Stereotactic Body Radiosurgery for Metastatic Gynecologic Malignancies. SO - Frontiers in Oncology. 2:181, 2012 AS - Front. oncol.. 2:181, 2012 NJ - Frontiers in oncology PI - Journal available in: Electronic-eCollection PI - Citation processed from: Internet JC - 101568867 IO - Front Oncol PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514687 CP - Switzerland KW - Cyberknife; gynecologic cancer; robotic radiosurgery AB - BACKGROUND: Recurrent gynecologic cancers are often difficult to manage without significant morbidity. We conducted a phase II study to assess the safety and the efficacy of ablative robotic stereotactic body radiosurgery (SBRT) in women with metastatic gynecologic cancers. AB - METHODS: A total of 50 patients with recurrent gynecologic cancer who had single or multiple (<4) metastases underwent robotic-armed Cyberknife SBRT (24Gy/3 daily doses). Toxicities were graded prospectively by common toxicity criteria for adverse events (version 4.0). SBRT target responses were recorded following RECIST criteria (version 1.0). Rates of clinical benefit for SBRT and non-radiosurgical disease relapse were calculated. Disease-free and overall survivals were estimated by the Kaplan-Meier method and the Cox proportional hazards model was used to control for prognostic variables. AB - FINDINGS: SBRT was safely delivered, with 49 (98%) of 50 patients completing three prescribed fractions. The most frequent grade 2 or higher adverse events attributed to SBRT included fatigue (16%), nausea (8%), and diarrhea (4%). One (2%) grade four hyperbilirubinemia occurred. SBRT target response was 96% (48 of 50 patients). A 6-month clinical benefit was recorded in 34 [68% (95% CI, 53.2, 80.1)] patients. No SBRT targeted disease progressed. Non-radiosurgical disease relapse occurred in 31 (62%) patients. Median disease-free survival was 7.8months (95% CI, 4.0, 11.6). Median overall survival was 20.2months (95% CI, 10.9, 29.5). AB - INTERPRETATION: SBRT safely controlled metastatic gynecologic cancer targets. Given an observed high rate of non-radiosurgical disease relapse, a phase I trial assessing co-administration of SBRT and cytotoxic chemotherapy is underway. AB - FUNDING: Case Comprehensive Cancer Center. ES - 2234-943X IL - 2234-943X DO - https://dx.doi.org/10.3389/fonc.2012.00181 PT - Journal Article ID - 23227452 [pubmed] ID - 10.3389/fonc.2012.00181 [doi] ID - PMC3514687 [pmc] PP - epublish PH - 2012/10/08 [received] PH - 2012/11/10 [accepted] LG - English EP - 20121205 DP - 2012 DC - 20121211 EZ - 2012/12/11 06:00 DA - 2012/12/12 06:01 DT - 2012/12/12 06:00 YR - 2012 ED - 20121212 RD - 20140731 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=23227452 <332. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22250958 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tobis S AU - Knopf JK AU - Silvers C AU - Messing E AU - Yao J AU - Rashid H AU - Wu G AU - Golijanin D FA - Tobis, Scott FA - Knopf, Joy K FA - Silvers, Christopher FA - Messing, Edward FA - Yao, Jorge FA - Rashid, Hani FA - Wu, Guan FA - Golijanin, Dragan IN - Tobis, Scott. Department of Urology, University of Rochester Medical Center, Rochester, New York, USA. TI - Robot-assisted and laparoscopic partial nephrectomy with near infrared fluorescence imaging. SO - Journal of Endourology. 26(7):797-802, 2012 Jul AS - J Endourol. 26(7):797-802, 2012 Jul NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - Demography MH - Female MH - Humans MH - Kidney Neoplasms/pa [Pathology] MH - Kidney Neoplasms/su [Surgery] MH - *Laparoscopy MH - Male MH - Middle Aged MH - *Nephrectomy/mt [Methods] MH - *Robotics/mt [Methods] MH - *Spectroscopy, Near-Infrared/mt [Methods] AB - BACKGROUND AND PURPOSE: Recent literature has focused on the importance of maximal nephron preservation during partial nephrectomy to avoid complications associated with chronic renal insufficiency. Accurate differentiation of tumor from normal surrounding parenchyma is critical to ensure excessive normal renal tissue is not made ischemic or excised along with the tumor. The feasibility of a novel intraoperative imaging technique to differentiate tumor from surrounding parenchyma during laparoscopic and robot-assisted partial nephrectomy was evaluated. AB - PATIENTS AND METHODS: Patients who were scheduled to undergo laparoscopic or robot-assisted partial nephrectomy were recruited from April 2009 to July 2010. The Endoscopic SPY Imaging System was used as an adjunct to intraoperative imaging in all cases. Patients received intravenous injections of indocyanine green (ICG), which was visualized intraoperatively with the near infrared fluorescence (NIRF) imaging capability of the SPY scope. The degree of tumor fluorescence compared with surrounding renal parenchyma was qualitatively assessed before tumor resection, and partial nephrectomy was then performed with standard techniques while intermittently using NIRF imaging. AB - RESULTS: Nineteen patients underwent intravenous administration of ICG followed by NIRF during partial nephrectomy. Average tumor size was 3.0 cm (range 0.8-5.9 cm). Thirteen masses were malignant on final pathology results, and all of these were seen to be hypofluorescent compared with surrounding renal parenchyma during intraoperative imaging. The imaging behavior of benign tumors ranged from isofluorescent to hyperfluorescent compared with normal parenchyma. No complications were associated with ICG injection. AB - CONCLUSION: NIRF imaging after intravenous ICG administration may be a useful intraoperative imaging tool to differentiate malignant tumors from normal renal parenchyma during laparoscopic and robot-assisted partial nephrectomy. Advanced intraoperative imaging techniques such as this one may become increasingly helpful as more complicated tumors are resected with minimally invasive approaches. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2011.0604 PT - Clinical Trial PT - Journal Article ID - 22250958 [pubmed] ID - 10.1089/end.2011.0604 [doi] PP - ppublish LG - English EP - 20120302 DP - 2012 Jul DC - 20120711 EZ - 2012/01/19 06:00 DA - 2012/11/08 06:00 DT - 2012/01/19 06:00 YR - 2012 ED - 20121107 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22250958 <333. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22191496 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Beck SM AU - Skarecky D AU - Miller S AU - Ahlering TE FA - Beck, Shawn M FA - Skarecky, Douglas FA - Miller, Scott FA - Ahlering, Thomas E IN - Beck, Shawn M. Department of Urology, University of California, Irvine, Orange, California 92868. USA. TI - Athermal tension adjustable suture ligation of the vascular pedicle during robot-assisted prostatectomy. SO - Journal of Endourology. 26(7):834-7, 2012 Jul AS - J Endourol. 26(7):834-7, 2012 Jul NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727628 SB - Index Medicus CP - United States MH - Humans MH - Ligation MH - Male MH - Middle Aged MH - *Prostate/bs [Blood Supply] MH - *Prostate/su [Surgery] MH - *Prostatectomy/mt [Methods] MH - Reference Standards MH - *Robotics/mt [Methods] MH - *Sutures MH - *Temperature AB - PURPOSE: We report a simple figure-of-eight tension adjustable suture to ligate the vascular pedicle (VP) during robot-assisted radical prostatectomy (RARP). AB - MATERIALS AND METHODS: During nerve-sparing RARP, after the rectum has been mobilized, the VP is isolated and prepared for transection. Previous reports describe placing of hemostatic clips (metallic or Hem-o-lokTM) or laparoscopic bulldog clamps (30 mm) to control and oversew the VP; both techniques are quite assistant dependent. We present a bulldog clamp alternative by placing a figure-of-eight fashion, a 6-cm 3-0 poliglecaprone on an SH needle with a small loop tied in the suture end. After the needle has been placed through the VP, it is then threaded through the preformed loop and then a small Hem-o-lok clip is placed and cinched down to occlude the blood vessels. Next, the VPs are transected. The clip can be further cinched, mimicking the technique used in partial nephrectomy, to control bleeding when encountered. Data were collected prospectively to demonstrate safety. AB - RESULTS: We report on 74 men totaling 143 VPs using this new technique. The average operative time was reduced by 15 minutes compared with using bulldog clamps. In the initial 10 cases (20 attempts), inadvertent transection of the suture occurred three times. In these three cases, hemostasis was (easily) controlled with additional sutures. AB - CONCLUSIONS: The pedicle stitch technique offers an assistant independent alternative for a simple and precise athermal means to control the VP. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2011.0063 PT - Clinical Trial PT - Journal Article ID - 22191496 [pubmed] ID - 10.1089/end.2011.0063 [doi] ID - PMC3727628 [pmc] PP - ppublish GI - No: P30 CA062203 Organization: (CA) *NCI NIH HHS* Country: United States LG - English EP - 20111222 DP - 2012 Jul DC - 20120711 EZ - 2011/12/24 06:00 DA - 2012/11/08 06:00 DT - 2011/12/24 06:00 YR - 2012 ED - 20121107 RD - 20161025 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22191496 <334. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22260307 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hurtes X AU - Roupret M AU - Vaessen C AU - Pereira H AU - Faivre d'Arcier B AU - Cormier L AU - Bruyere F FA - Hurtes, Xavier FA - Roupret, Morgan FA - Vaessen, Christophe FA - Pereira, Helder FA - Faivre d'Arcier, Benjamin FA - Cormier, Luc FA - Bruyere, Franck IN - Hurtes, Xavier. Urology Department, University Hospital of Tours, Tours, France. hurtesx@gmail.com TI - Anterior suspension combined with posterior reconstruction during robot-assisted laparoscopic prostatectomy improves early return of urinary continence: a prospective randomized multicentre trial. CM - Comment in: Urol Oncol. 2013 Feb;31(2):272-3; PMID: 23465473 CM - Comment in: J Urol. 2013 May;189(5):1717; PMID: 23594631 SO - BJU International. 110(6):875-83, 2012 Sep AS - BJU Int. 110(6):875-83, 2012 Sep NJ - BJU international PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - dcu, 100886721 IO - BJU Int. SB - Index Medicus CP - England MH - Humans MH - *Laparoscopy MH - Male MH - Middle Aged MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - Recovery of Function MH - *Robotics MH - Single-Blind Method MH - Time Factors MH - *Urination AB - UNLABELLED: What's known on the subject? and What does the study add? Urinary incontinence is one of the major drawbacks of radical prostatectomy, regardless of the procedure used (i.e. open, laparoscopic or robotic-assisted). Several technical modifications have been described to improve postoperative continence, highlighting the role of puboprostatic ligaments and posterior reconstruction of the rhabdomyosphincter. The results obtained are inconsistent when applied to robotic surgery. The present multicentre randomized study shows that anterior suspension combined with posterior reconstruction is a safe and easy-to-perform technique for improving early continence after robotic-assisted laparoscopic prostatectomy. AB - OBJECTIVE: To assess the impact on urinary continence of anterior retropubic suspension with posterior reconstruction during robot-assisted laparoscopic prostatectomy (RALP). AB - PATIENTS AND METHODS: In total, 72 patients who were due to undergo prostatectomy between July 2009 and July 2010 were prospectively randomized into two groups: group A underwent a standard RALP procedure and group B had anterior suspension and posterior reconstruction during RALP. The primary outcome measure was urinary continence, assessed using the University of California Los Angeles Prostate Cancer Index questionnaire at 15 days, and at 1, 3 and 6 months, after surgery. Other data recorded were operation duration, blood loss, length of hospital stay, duration of bladder catheterization, complications and positive margin rate. AB - RESULTS: The continence rates at 15 days, and at 1, 3 and 6 months, after surgery were 3.6%, 7.1%, 15.4% and 57.9%, respectively, in group A, and 5.9%, 26.5%, 45.2% and 65.4%, respectively, in group B. The continence rates differed statistically between groups at 1 and 3 months (P = 0.047 and P = 0.016, respectively). There was no significant difference between groups regarding complications (P = 0.8) or positive margin rate (P = 0.46). AB - CONCLUSION: Anterior suspension associated with posterior reconstruction during RALP improved the early return of continence, without increasing complications. AB - Copyright © 2012 BJU INTERNATIONAL. ES - 1464-410X IL - 1464-4096 DO - https://dx.doi.org/10.1111/j.1464-410X.2011.10849.x PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial ID - 22260307 [pubmed] ID - 10.1111/j.1464-410X.2011.10849.x [doi] PP - ppublish LG - English EP - 20120119 DP - 2012 Sep DC - 20120828 EZ - 2012/01/21 06:00 DA - 2012/11/01 06:00 DT - 2012/01/21 06:00 YR - 2012 ED - 20121031 RD - 20130530 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22260307 <335. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22914470 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sarlos D AU - Kots L AU - Stevanovic N AU - von Felten S AU - Schar G FA - Sarlos, Dimitri FA - Kots, LaVonne FA - Stevanovic, Nebojsa FA - von Felten, Stefanie FA - Schar, Gabriel IN - Sarlos, Dimitri. Department of Obstetrics and Gynaecology, Kantonsspital Aarau, Aarau, Switzerland. Dimitri.Sarlos@ksa.ch TI - Robotic compared with conventional laparoscopic hysterectomy: a randomized controlled trial. SO - Obstetrics & Gynecology. 120(3):604-11, 2012 Sep AS - Obstet Gynecol. 120(3):604-11, 2012 Sep NJ - Obstetrics and gynecology PI - Journal available in: Print PI - Citation processed from: Internet JC - oc2, 0401101 IO - Obstet Gynecol SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Analgesics/tu [Therapeutic Use] MH - Blood Loss, Surgical/sn [Statistics & Numerical Data] MH - Female MH - Humans MH - *Hysterectomy/mt [Methods] MH - *Laparoscopy/mt [Methods] MH - Middle Aged MH - Outcome Assessment (Health Care) MH - Pain, Postoperative/dt [Drug Therapy] MH - Pain, Postoperative/ep [Epidemiology] MH - Pain, Postoperative/et [Etiology] MH - Postoperative Complications/ep [Epidemiology] MH - Postoperative Complications/et [Etiology] MH - Quality of Life MH - Recovery of Function MH - *Robotics MH - Time Factors AB - OBJECTIVE: To compare surgical outcome and quality of life of robot-assisted laparoscopic hysterectomy with conventional laparoscopic hysterectomy. AB - METHODS: For this controlled clinical trial, patients with benign indications for hysterectomy were randomized to receive either a robotic (robotic group) or conventional laparoscopic hysterectomy (conventional group). The primary end point was total operating time; secondary end points were perioperative outcome, blood loss, and the change in quality of life. AB - RESULTS: Ninety-five patients out of 100 randomized patients completed the study. Patient age, body mass index, and uterus weight showed no significant differences between both groups. All results are given as mean (+/- standard deviation; median). Total operating time for the robotic group was significantly higher with 106 (+/- 29; 103) compared with 75 (+/- 21; 74) (conventional group) minutes. Blood loss, complications, analgesics use, and return to activity for both groups were comparable. The change in preoperative to postoperative quality-of-life index (quality of life measured on a linear scale from 0 to 100) was significantly higher in the robotic group, with 13 (+/- 10; 13) compared with 5 (+/- 14; 5) (conventional group). AB - CONCLUSION: Robot-assisted laparoscopic hysterectomy and conventional laparoscopy compare well in most surgical aspects, but the robotic procedure is associated with longer operating times. Postoperative quality-of-life index was better; however, long-term, there was no difference. However, subjective postoperative parameters such as analgesic use and return to activity showed no significant difference between both groups. RN - 0 (Analgesics) ES - 1873-233X IL - 0029-7844 DI - 00006250-201209000-00016 DO - https://dx.doi.org/10.1097/AOG.0b013e318265b61a PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 22914470 [pubmed] ID - 10.1097/AOG.0b013e318265b61a [doi] ID - 00006250-201209000-00016 [pii] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT00683293 SL - https://clinicaltrials.gov/search/term=NCT00683293 LG - English DP - 2012 Sep DC - 20120823 EZ - 2012/08/24 06:00 DA - 2012/10/30 06:00 DT - 2012/08/24 06:00 YR - 2012 ED - 20121029 RD - 20120823 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22914470 <336. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22473107 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Benazzo M AU - Canzi P AU - Occhini A FA - Benazzo, Marco FA - Canzi, Pietro FA - Occhini, Antonio IN - Benazzo, Marco. Department of Otorhinolaryngology, University of Pavia, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy. pcanzio@hotmail.com TI - Transoral robotic surgery with laser for head and neck cancers: a feasibility study. SO - Orl; Journal of Oto-Rhino-Laryngology & its Related Specialties. 74(3):124-8, 2012 AS - ORL J Otorhinolaryngol Relat Spec. 74(3):124-8, 2012 NJ - ORL; journal for oto-rhino-laryngology and its related specialties PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - oke, 0334721 IO - ORL J. Otorhinolaryngol. Relat. Spec. SB - Index Medicus CP - Switzerland MH - Aged MH - Carcinoma, Squamous Cell/pa [Pathology] MH - *Carcinoma, Squamous Cell/su [Surgery] MH - Feasibility Studies MH - Female MH - Humans MH - Laser Therapy/is [Instrumentation] MH - *Laser Therapy/mt [Methods] MH - Lasers, Gas/tu [Therapeutic Use] MH - Male MH - Middle Aged MH - Oropharyngeal Neoplasms/pa [Pathology] MH - *Oropharyngeal Neoplasms/su [Surgery] MH - Pilot Projects MH - Robotics/is [Instrumentation] MH - *Robotics/mt [Methods] MH - Thulium MH - Tongue Neoplasms/pa [Pathology] MH - *Tongue Neoplasms/su [Surgery] AB - AIMS: To assess the feasibility of a flexible thulium laser coupled with a novel robotic introducer for head and neck cancers. AB - METHODS: In a prospective nonrandomized clinical trial, 58 patients were evaluated. When indicated, transoral robotic surgery (TORS) with laser was performed using an Intuitive da Vinci S System with the Intuitive Surgical Endo Wrist Introducer, 5Fr to hold and position thulium surgical laser fibers. AB - RESULTS: Six patients underwent TORS with laser for early supraglottic and oropharyngeal squamous cell carcinomas. All approaches were successfully completed without the need for microscopic/open conversion or positive margins to the final pathological study. No intraoperative adverse events occurred and recovery was relatively quick, with no evidence of disease recurrence at the time of reporting, the short observation time notwithstanding. AB - CONCLUSIONS: In our preliminary experience, TORS with laser showed feasible and promising results. Further studies are mandatory to demonstrate thulium laser benefits in surgical and oncological practice. AB - Copyright © 2012 S. Karger AG, Basel. RN - 8RKC5ATI4P (Thulium) ES - 1423-0275 IL - 0301-1569 DI - 000337092 DO - https://dx.doi.org/10.1159/000337092 PT - Clinical Trial PT - Journal Article ID - 22473107 [pubmed] ID - 000337092 [pii] ID - 10.1159/000337092 [doi] PP - ppublish PH - 2011/09/01 [received] PH - 2012/01/31 [accepted] LG - English EP - 20120329 DP - 2012 DC - 20120619 EZ - 2012/04/05 06:00 DA - 2012/10/26 06:00 DT - 2012/04/05 06:00 YR - 2012 ED - 20121025 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22473107 <337. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22118291 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lie M AU - May C AU - Kelly T AU - Robson S FA - Lie, Mabel FA - May, Carl FA - Kelly, Teresa FA - Robson, Stephen IN - Lie, Mabel. Institute of Health and Society, Newcastle University Faculty of Health Sciences, University of Southampton Institute of Cellular Medicine, Newcastle University, Richardson Road, Newcastle upon Tyne. mabel.lie@newcastle.ac.uk TI - 'Let the computer choose?': the experience of participants in a randomised preference trial of medical versus surgical termination of pregnancy. SO - Sociology of Health & Illness. 34(5):746-60, 2012 Jun AS - Sociol Health Illn. 34(5):746-60, 2012 Jun NJ - Sociology of health & illness PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 8205036, 100554340, ut3 IO - Sociol Health Illn SB - Index Medicus CP - England MH - *Abortifacient Agents, Nonsteroidal/ad [Administration & Dosage] MH - *Abortion, Induced/mt [Methods] MH - *Abortion, Induced/px [Psychology] MH - Adult MH - Alprostadil/ad [Administration & Dosage] MH - Alprostadil/aa [Analogs & Derivatives] MH - Choice Behavior MH - Female MH - Follow-Up Studies MH - Health Status MH - Humans MH - Mental Health MH - Mifepristone/ad [Administration & Dosage] MH - Patient Satisfaction MH - Pregnancy MH - Pregnancy Trimester, First MH - *Randomized Controlled Trials as Topic/px [Psychology] MH - Reproductive Medicine MH - *Vacuum Extraction, Obstetrical/px [Psychology] AB - The termination of pregnancy trial (Newcastle upon Tyne, UK), is the only randomised trial on termination of pregnancy methods incorporating a qualitative element that aimed to understand the experiences of women participating in the trial. Based on the results of this qualitative work, this article aims to provide insights into two strands of understanding; firstly, women's experience of participating in research about abortion and secondly, their experience of participating in a randomised preference trial. Semi-structured interviews were conducted of up to 90 minutes with 30 participants recruited at a single hospital site. A total of 20 women from the preference arm and 10 from the random arm were interviewed. The analysis and discussion of our findings use reflexive modernisation as a framework for understanding and interpreting some of the actions of social agents, that is, the participants and trial recruiters in the course of a clinical trial as an expert system. We found that the factors that shape women's experiences and decisions include trust in the expert system and reflexivity and agency on the part of both participants and trial recruiters. AB - Copyright © 2011 The Authors. Sociology of Health & Illness © 2011 Foundation for the Sociology of Health & Illness/Blackwell Publishing Ltd. RN - 0 (Abortifacient Agents, Nonsteroidal) RN - 320T6RNW1F (Mifepristone) RN - 45KZB1FOLS (gemeprost) RN - F5TD010360 (Alprostadil) ES - 1467-9566 IL - 0141-9889 DO - https://dx.doi.org/10.1111/j.1467-9566.2011.01412.x PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 22118291 [pubmed] ID - 10.1111/j.1467-9566.2011.01412.x [doi] PP - ppublish LG - English EP - 20111125 DP - 2012 Jun DC - 20120613 EZ - 2011/11/29 06:00 DA - 2012/10/25 06:00 DT - 2011/11/29 06:00 YR - 2012 ED - 20121024 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22118291 <338. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22864881 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Park JS AU - Choi GS AU - Park SY AU - Kim HJ AU - Ryuk JP FA - Park, J S FA - Choi, G-S FA - Park, S Y FA - Kim, H J FA - Ryuk, J P IN - Park, J S. Colorectal Cancer Centre, Kyungpook National University Medical Centre, School of Medicine, Kyungpook National University, 474 Hakjeongdong, Buk-gu, Daegu 702-210, Korea. TI - Randomized clinical trial of robot-assisted versus standard laparoscopic right colectomy. SO - British Journal of Surgery. 99(9):1219-26, 2012 Sep AS - Br J Surg. 99(9):1219-26, 2012 Sep NJ - The British journal of surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - b34, 0372553 IO - Br J Surg SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - Aged MH - Colectomy/ec [Economics] MH - *Colectomy/mt [Methods] MH - Colonic Neoplasms/ec [Economics] MH - *Colonic Neoplasms/su [Surgery] MH - Costs and Cost Analysis MH - Feasibility Studies MH - Female MH - Humans MH - Intraoperative Complications/et [Etiology] MH - Laparoscopy/ec [Economics] MH - *Laparoscopy/mt [Methods] MH - Length of Stay MH - Lymph Node Excision/ec [Economics] MH - Lymph Node Excision/mt [Methods] MH - Male MH - Middle Aged MH - Postoperative Complications/et [Etiology] MH - Robotics/ec [Economics] MH - *Robotics/mt [Methods] MH - Treatment Outcome AB - BACKGROUND: Robotic surgery was invented to overcome the demerits of laparoscopic technique. However, it is unclear whether robot-assisted colectomy (RAC) has significant clinical advantages over laparoscopically assisted colectomy (LAC) in treating colonic cancer. The aim of this study was to compare the surgical outcomes of RAC versus LAC for right-sided colonic cancer. AB - METHODS: Patients with right-sided colonic cancer were randomized to receive RAC or LAC. The primary outcome measure was length of hospital stay. Secondary outcomes were duration of operation, morbidity, postoperative pain, hospital costs and pathological quality of the specimen. AB - RESULTS: Of 71 patients randomized, 70 (35 in each group) were included in the analysis. Hospital stay, surgical complications, postoperative pain score, resection margin clearance and number of lymph nodes harvested were similar in both groups. The duration of surgery was longer in the RAC group (195 versus 130 min; P < 0.001). No conversion to open surgery was needed in either group. Overall hospital costs were significantly higher for RAC (US $ 12,235 versus $ 10,320; P = 0.013); the higher costs were attributed primarily to the costs of surgery, including consumables. AB - CONCLUSION: Robotic-assisted laparoscopic right colectomy was feasible but provided no benefit to justify the greater cost. AB - REGISTRATION NUMBER: NCT01042743 (http://www.clinicaltrials.gov). AB - Copyright © 2012 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. ES - 1365-2168 IL - 0007-1323 DO - https://dx.doi.org/10.1002/bjs.8841 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 22864881 [pubmed] ID - 10.1002/bjs.8841 [doi] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01042743 SL - https://clinicaltrials.gov/search/term=NCT01042743 LG - English DP - 2012 Sep DC - 20120806 EZ - 2012/08/07 06:00 DA - 2012/10/16 06:00 DT - 2012/08/07 06:00 YR - 2012 ED - 20121015 RD - 20140731 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22864881 <339. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22732135 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kauer SD AU - Reid SC AU - Crooke AH AU - Khor A AU - Hearps SJ AU - Jorm AF AU - Sanci L AU - Patton G FA - Kauer, Sylvia Deidre FA - Reid, Sophie Caroline FA - Crooke, Alexander Hew Dale FA - Khor, Angela FA - Hearps, Stephen John Charles FA - Jorm, Anthony Francis FA - Sanci, Lena FA - Patton, George IN - Kauer, Sylvia Deidre. Centre for Adolescent Health, Royal Children's Hospital & Murdoch Childrens Research Institute, Parkville, VIC, Australia. sylvia.kauer@mcri.edu.au TI - Self-monitoring using mobile phones in the early stages of adolescent depression: randomized controlled trial. SO - Journal of Medical Internet Research. 14(3):e67, 2012 Jun 25 AS - J Med Internet Res. 14(3):e67, 2012 Jun 25 NJ - Journal of medical Internet research PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 100959882 IO - J. Med. Internet Res. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414872 SB - Index Medicus CP - Canada MH - Adolescent MH - Adult MH - *Cell Phones MH - Depression/px [Psychology] MH - *Depression/th [Therapy] MH - Humans MH - *Self-Assessment MH - Young Adult AB - BACKGROUND: The stepped-care approach, where people with early symptoms of depression are stepped up from low-intensity interventions to higher-level interventions as needed, has the potential to assist many people with mild depressive symptoms. Self-monitoring techniques assist people to understand their mental health symptoms by increasing their emotional self-awareness (ESA) and can be easily distributed on mobile phones at low cost. Increasing ESA is an important first step in psychotherapy and has the potential to intervene before mild depressive symptoms progress to major depressive disorder. In this secondary analysis we examined a mobile phone self-monitoring tool used by young people experiencing mild or more depressive symptoms to investigate the relationships between self-monitoring, ESA, and depression. AB - OBJECTIVES: We tested two main hypotheses: (1) people who monitored their mood, stress, and coping strategies would have increased ESA from pretest to 6-week follow-up compared with an attention comparison group, and (2) an increase in ESA would predict a decrease in depressive symptoms. AB - METHODS: We recruited patients aged 14 to 24 years from rural and metropolitan general practices. Eligible participants were identified as having mild or more mental health concerns by their general practitioner. Participants were randomly assigned to either the intervention group (where mood, stress, and daily activities were monitored) or the attention comparison group (where only daily activities were monitored), and both groups self-monitored for 2 to 4 weeks. Randomization was carried out electronically via random seed generation, by an in-house computer programmer; therefore, general practitioners, participants, and researchers were blinded to group allocation at randomization. Participants completed pretest, posttest, and 6-week follow-up measures of the Depression Anxiety Stress Scale and the ESA Scale. We estimated a parallel process latent growth curve model (LGCM) using Mplus to test the indirect effect of the intervention on depressive symptoms via the mediator ESA, and calculated 95% bias-corrected bootstrapping confidence intervals (CIs). AB - RESULTS: Of the 163 participants assessed for eligibility, 118 were randomly assigned and 114 were included in analyses (68 in the intervention group and 46 in the comparison group). A parallel process LGCM estimated the indirect effect of the intervention on depressive symptoms via ESA and was shown to be statistically significant based on the 95% bias-corrected bootstrapping CIs not containing zero (-6.366 to -0.029). The proportion of the maximum possible indirect effect estimated was kappa(2 )=.54 (95% CI .426-.640). AB - CONCLUSIONS: This study supported the hypothesis that self-monitoring increases ESA, which in turn decreases depressive symptoms for young people with mild or more depressive symptoms. Mobile phone self-monitoring programs are ideally suited to first-step intervention programs for depression in the stepped-care approach, particularly when ESA is targeted as a mediating factor. AB - TRIAL REGISTRATION: ClinicalTrials.gov NCT00794222; http://clinicaltrials.gov/ct2/show/NCT00794222 (Archived by WebCite at http://www.webcitation.org/65lldW34k). ES - 1438-8871 IL - 1438-8871 DI - v14i3e67 DO - https://dx.doi.org/10.2196/jmir.1858 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 22732135 [pubmed] ID - v14i3e67 [pii] ID - 10.2196/jmir.1858 [doi] ID - PMC3414872 [pmc] PP - epublish PH - 2011/06/08 [received] PH - 2011/08/23 [accepted] PH - 2011/08/18 [revised] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT00794222 SL - https://clinicaltrials.gov/search/term=NCT00794222 LG - English EP - 20120625 DP - 2012 Jun 25 DC - 20120626 EZ - 2012/06/27 06:00 DA - 2012/10/02 06:00 DT - 2012/06/27 06:00 YR - 2012 ED - 20121001 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=22732135 <340. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22732135 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kauer SD AU - Reid SC AU - Crooke AH AU - Khor A AU - Hearps SJ AU - Jorm AF AU - Sanci L AU - Patton G FA - Kauer, Sylvia Deidre FA - Reid, Sophie Caroline FA - Crooke, Alexander Hew Dale FA - Khor, Angela FA - Hearps, Stephen John Charles FA - Jorm, Anthony Francis FA - Sanci, Lena FA - Patton, George IN - Kauer, Sylvia Deidre. Centre for Adolescent Health, Royal Children's Hospital & Murdoch Childrens Research Institute, Parkville, VIC, Australia. sylvia.kauer@mcri.edu.au TI - Self-monitoring using mobile phones in the early stages of adolescent depression: randomized controlled trial. SO - Journal of Medical Internet Research. 14(3):e67, 2012 Jun 25 AS - J Med Internet Res. 14(3):e67, 2012 Jun 25 NJ - Journal of medical Internet research PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 100959882 IO - J. Med. Internet Res. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414872 SB - Index Medicus CP - Canada MH - Adolescent MH - Adult MH - *Cell Phones MH - Depression/px [Psychology] MH - *Depression/th [Therapy] MH - Humans MH - *Self-Assessment MH - Young Adult AB - BACKGROUND: The stepped-care approach, where people with early symptoms of depression are stepped up from low-intensity interventions to higher-level interventions as needed, has the potential to assist many people with mild depressive symptoms. Self-monitoring techniques assist people to understand their mental health symptoms by increasing their emotional self-awareness (ESA) and can be easily distributed on mobile phones at low cost. Increasing ESA is an important first step in psychotherapy and has the potential to intervene before mild depressive symptoms progress to major depressive disorder. In this secondary analysis we examined a mobile phone self-monitoring tool used by young people experiencing mild or more depressive symptoms to investigate the relationships between self-monitoring, ESA, and depression. AB - OBJECTIVES: We tested two main hypotheses: (1) people who monitored their mood, stress, and coping strategies would have increased ESA from pretest to 6-week follow-up compared with an attention comparison group, and (2) an increase in ESA would predict a decrease in depressive symptoms. AB - METHODS: We recruited patients aged 14 to 24 years from rural and metropolitan general practices. Eligible participants were identified as having mild or more mental health concerns by their general practitioner. Participants were randomly assigned to either the intervention group (where mood, stress, and daily activities were monitored) or the attention comparison group (where only daily activities were monitored), and both groups self-monitored for 2 to 4 weeks. Randomization was carried out electronically via random seed generation, by an in-house computer programmer; therefore, general practitioners, participants, and researchers were blinded to group allocation at randomization. Participants completed pretest, posttest, and 6-week follow-up measures of the Depression Anxiety Stress Scale and the ESA Scale. We estimated a parallel process latent growth curve model (LGCM) using Mplus to test the indirect effect of the intervention on depressive symptoms via the mediator ESA, and calculated 95% bias-corrected bootstrapping confidence intervals (CIs). AB - RESULTS: Of the 163 participants assessed for eligibility, 118 were randomly assigned and 114 were included in analyses (68 in the intervention group and 46 in the comparison group). A parallel process LGCM estimated the indirect effect of the intervention on depressive symptoms via ESA and was shown to be statistically significant based on the 95% bias-corrected bootstrapping CIs not containing zero (-6.366 to -0.029). The proportion of the maximum possible indirect effect estimated was kappa(2 )=.54 (95% CI .426-.640). AB - CONCLUSIONS: This study supported the hypothesis that self-monitoring increases ESA, which in turn decreases depressive symptoms for young people with mild or more depressive symptoms. Mobile phone self-monitoring programs are ideally suited to first-step intervention programs for depression in the stepped-care approach, particularly when ESA is targeted as a mediating factor. AB - TRIAL REGISTRATION: ClinicalTrials.gov NCT00794222; http://clinicaltrials.gov/ct2/show/NCT00794222 (Archived by WebCite at http://www.webcitation.org/65lldW34k). ES - 1438-8871 IL - 1438-8871 DI - v14i3e67 DO - https://dx.doi.org/10.2196/jmir.1858 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 22732135 [pubmed] ID - v14i3e67 [pii] ID - 10.2196/jmir.1858 [doi] ID - PMC3414872 [pmc] PP - epublish PH - 2011/06/08 [received] PH - 2011/08/23 [accepted] PH - 2011/08/18 [revised] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT00794222 SA - ClinicalTrials.gov/NCT00794222 SL - https://clinicaltrials.gov/search/term=NCT00794222 SL - https://clinicaltrials.gov/search/term=NCT00794222 LG - English EP - 20120625 DP - 2012 Jun 25 DC - 20120626 EZ - 2012/06/27 06:00 DA - 2012/10/02 06:00 DT - 2012/06/27 06:00 YR - 2012 ED - 20121001 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22732135 <341. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22213406 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Modabber A AU - Legros C AU - Rana M AU - Gerressen M AU - Riediger D AU - Ghassemi A FA - Modabber, Ali FA - Legros, Christina FA - Rana, Majeed FA - Gerressen, Marcus FA - Riediger, Dieter FA - Ghassemi, Alireza IN - Modabber, Ali. Department of Oral, Maxillofacial and Plastic Facial Surgery, University Hospital Aachen, Germany. amodabber@ukaachen.de TI - Evaluation of computer-assisted jaw reconstruction with free vascularized fibular flap compared to conventional surgery: a clinical pilot study. SO - The International Journal Of Medical Robotics + Computer Assisted Surgery: MRCAS. 8(2):215-20, 2012 Jun AS - Int J Med Robot. 8(2):215-20, 2012 Jun NJ - The international journal of medical robotics + computer assisted surgery : MRCAS PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101250764 IO - Int J Med Robot SB - Index Medicus CP - England MH - Adult MH - Aged MH - Diagnosis, Computer-Assisted MH - Equipment Design MH - Female MH - *Fibula/su [Surgery] MH - Fibula/tr [Transplantation] MH - *Free Tissue Flaps MH - Humans MH - Imaging, Three-Dimensional MH - *Jaw/su [Surgery] MH - Male MH - Middle Aged MH - Models, Statistical MH - Pilot Projects MH - *Reconstructive Surgical Procedures/mt [Methods] MH - Robotics MH - *Surgery, Computer-Assisted/mt [Methods] MH - Treatment Outcome AB - BACKGROUND: The introduction of computer-assisted surgery was a milestone in functional reconstructions of facial skeletal defects. AB - PATIENTS AND METHODS: We compared five computer-assisted and five conventional reconstructions with fibular grafts in the course of a pilot study. A rapid prototyping guide translated the computer-assisted surgery plan into intraoperative utilizable models. We intraoperatively measured the time needed for shaping the graft to the recipient site and the ischaemic time. Furthermore, the size of donor site defect compared to the required transplant length was evaluated. AB - RESULTS: Shaping procedure and ischaemic time turned out significantly shorter when compared to conventional surgery without cutting guide (p=0.014). Using surgical guides, there was no change between the defect size of the fibula and the necessary transplant size. In conventional surgery, a mean change of 1.92cm occurred (p=0.001). AB - CONCLUSION: The surgical guide significantly reduced shaping time and consequently ischaemic time. These factors can influence flap survival. The fibular donor site defect was downsized. AB - Copyright © 2011 John Wiley & Sons, Ltd. ES - 1478-596X IL - 1478-5951 DO - https://dx.doi.org/10.1002/rcs.456 PT - Comparative Study PT - Journal Article ID - 22213406 [pubmed] ID - 10.1002/rcs.456 [doi] PP - ppublish PH - 2011/11/08 [received] LG - English EP - 20111230 DP - 2012 Jun DC - 20120528 EZ - 2012/01/04 06:00 DA - 2012/09/27 06:00 DT - 2012/01/04 06:00 YR - 2012 ED - 20120926 RD - 20120528 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22213406 <342. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22134121 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bernardini MQ AU - Gien LT AU - Tipping H AU - Murphy J AU - Rosen BP FA - Bernardini, Marcus Q FA - Gien, Lilian T FA - Tipping, Helen FA - Murphy, Joan FA - Rosen, Barry P IN - Bernardini, Marcus Q. Division of Gynecologic Oncology, Princess Margaret Hospital, Ontario, Canada. Marcus.bernardini@uhn.on.ca TI - Surgical outcome of robotic surgery in morbidly obese patient with endometrial cancer compared to laparotomy. SO - International Journal of Gynecological Cancer. 22(1):76-81, 2012 Jan AS - Int J Gynecol Cancer. 22(1):76-81, 2012 Jan NJ - International journal of gynecological cancer : official journal of the International Gynecological Cancer Society PI - Journal available in: Print PI - Citation processed from: Internet JC - dzp, 9111626 IO - Int. J. Gynecol. Cancer SB - Index Medicus CP - United States MH - Adenocarcinoma, Clear Cell/co [Complications] MH - Adenocarcinoma, Clear Cell/su [Surgery] MH - Adult MH - Aged MH - Aged, 80 and over MH - Carcinosarcoma/co [Complications] MH - Carcinosarcoma/su [Surgery] MH - Endometrial Neoplasms/co [Complications] MH - *Endometrial Neoplasms/su [Surgery] MH - Female MH - Humans MH - Hysterectomy/is [Instrumentation] MH - *Hysterectomy/mt [Methods] MH - Intraoperative Complications/ep [Epidemiology] MH - *Laparotomy MH - Length of Stay/sn [Statistics & Numerical Data] MH - Middle Aged MH - Minimally Invasive Surgical Procedures/is [Instrumentation] MH - *Minimally Invasive Surgical Procedures/mt [Methods] MH - *Obesity, Morbid/co [Complications] MH - Postoperative Complications/ep [Epidemiology] MH - Prospective Studies MH - *Robotics MH - Treatment Outcome AB - INTRODUCTION: Before the introduction of robotic surgery at our institution, most obese women of class 2 or greater (body mass index [BMI] >35) underwent a laparotomy for the management of endometrial cancer. Since November 2008, we have performed most of these cases in a robotic fashion. This manuscript presents the outcome of these women in comparison with a historical cohort of women treated with laparotomy. AB - METHODS: Women with clinical stage I or II endometrial cancer and a BMI greater than 35 kg/m treated with robotic surgery at our institution between November 2008 and November 2010 were compared with a historical cohort of similar patients who underwent laparotomy. Patients' characteristics, operating room time, type of surgery, length of hospital stay, and incidence of perioperative complications were compared between the 2 groups. AB - RESULTS: A total of 86 women were analyzed in this study (robotic surgery, 45; laparotomy, 41). The overall intraoperative complication rate is 5.8%. There is no statistical difference in age, number of comorbidities, BMI, prior abdominal surgery, and operative complications between the women who underwent robotic surgery versus laparotomy. Postoperative complication rates are higher in the laparotomy group (44% vs 17.7%; P = 0.007), and hospital length of stay is also higher in the laparotomy group (4 vs 2 days; P < 0.001). There is no difference in rates of (pelvic) lymph node dissection; however, para-aortic node dissection is more common in the robotic surgery group. AB - CONCLUSION: Robotic surgery for the surgical management of the morbidly obese patient is shown to be safe and have less perioperative complications compared with open surgery. ES - 1525-1438 IL - 1048-891X DO - https://dx.doi.org/10.1097/IGC.0b013e3182353371 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 22134121 [pubmed] ID - 10.1097/IGC.0b013e3182353371 [doi] PP - ppublish LG - English DP - 2012 Jan DC - 20111223 EZ - 2011/12/03 06:00 DA - 2012/09/20 06:00 DT - 2011/12/03 06:00 YR - 2012 ED - 20120919 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22134121 <343. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22219470 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ma ZS AU - Dong MF AU - Yin QY AU - Feng ZY AU - Wang LX FA - Ma, Zeng-Shan FA - Dong, Ming-Feng FA - Yin, Qiu-Yang FA - Feng, Zhi-Yu FA - Wang, Le-Xin IN - Ma, Zeng-Shan. Department of Cardiac Surgery, Liaocheng People's Hospital and Liaocheng Clinical School of Taishan Medical University, Liaocheng, Shandong, China. TI - Totally thoracoscopic closure for atrial septal defect on perfused beating hearts. SO - European Journal of Cardio-Thoracic Surgery. 41(6):1316-9, 2012 Jun AS - Eur J Cardiothorac Surg. 41(6):1316-9, 2012 Jun NJ - European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - aoj, 8804069 IO - Eur J Cardiothorac Surg SB - Index Medicus CP - Germany MH - Adolescent MH - Adult MH - Child MH - Critical Care/sn [Statistics & Numerical Data] MH - Feasibility Studies MH - Female MH - Heart Arrest, Induced MH - *Heart Septal Defects, Atrial/su [Surgery] MH - Humans MH - Intraoperative Period MH - Length of Stay/sn [Statistics & Numerical Data] MH - Male MH - Middle Aged MH - Postoperative Care/mt [Methods] MH - Thoracoscopy/ae [Adverse Effects] MH - *Thoracoscopy/mt [Methods] MH - Treatment Outcome MH - Young Adult AB - OBJECTIVES: To investigate the feasibility and safety of non-robotically assisted totally thoracoscopic closure for atrial septal defect (ASD) on perfused beating hearts. AB - METHODS: Twenty-four patients (8-45 years, mean 14.4 +/- 18.7) underwent ASD closure on beating hearts by a totally thoracoscopic approach without the aid of a robotic surgical system. Additional 72 patients undergoing totally thoracoscopic ASD closure on cardioplegic arrested hearts were selected as a control. Cardiopulmonary bypass (CPB) was achieved peripherally. The aorta was not cross-clamped in the study group but it was cross-clamped in the control group. AB - RESULTS: ASD closure was successful in all study and control group patients without in-hospital mortality or major complications. The total duration of operation (76 +/- 9 vs. 98 +/- 6 min, P = 0.012), CPB time (32 +/- 5 vs. 48 +/- 4 min, P = 0.001), duration of intensive care stay (10.0 +/- 5.1 vs. 19.2 +/- 4.2 h, P = 0.003) and post-operative hospital stay (4.5 +/- 0.8 vs. 5.0 +/- 1.1 days, P = 0.045) in the study group were shorter than in the control group. There was no statistically significant difference in the proportion of patients requiring in-operation blood transfusion between study group and control group (25.0 vs. 36.1%, P = 0.226). Follow-up transthoracic echocardiography on Day 5 and Day 30 showed no residual shunts in study or control group patients. AB - CONCLUSIONS: Non-robotically assisted totally thoracoscopic closures of ASD on perfused beating hearts are feasible and safe. These procedures are associated with a shorter operation time and a shorter hospital stay than in surgeries on cardioplegic arrested hearts. ES - 1873-734X IL - 1010-7940 DI - ezr193 DO - https://dx.doi.org/10.1093/ejcts/ezr193 PT - Controlled Clinical Trial PT - Journal Article ID - 22219470 [pubmed] ID - ezr193 [pii] ID - 10.1093/ejcts/ezr193 [doi] PP - ppublish LG - English EP - 20111215 DP - 2012 Jun DC - 20120517 EZ - 2012/01/06 06:00 DA - 2012/08/29 06:00 DT - 2012/01/06 06:00 YR - 2012 ED - 20120828 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22219470 <344. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22339054 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Vora A AU - Mittal S AU - Hwang J AU - Bandi G FA - Vora, Anup FA - Mittal, Sameer FA - Hwang, Jonathan FA - Bandi, Gaurav IN - Vora, Anup. Department of Urology, Georgetown University Hospital, Washington, DC 20016, USA. anupvora@gmail.com TI - Robot-assisted simple prostatectomy: multi-institutional outcomes for glands larger than 100 grams. SO - Journal of Endourology. 26(5):499-502, 2012 May AS - J Endourol. 26(5):499-502, 2012 May NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Aged MH - Humans MH - Male MH - Middle Aged MH - Organ Size MH - Perioperative Care MH - *Prostate/pa [Pathology] MH - *Prostate/su [Surgery] MH - *Prostatectomy/mt [Methods] MH - *Robotics MH - Treatment Outcome AB - PURPOSE: To present our experience with robot-assisted simple prostatectomy in patients with large gland adenoma (>100 g) that would not be amenable to transurethral treatments. AB - PATIENTS AND METHODS: From August 2009 to May 2011, 13 robot-assisted simple suprapubic prostatectomies were performed in patients with symptomatic large gland (>100 g) prostatomegaly on transrectal ultrasonography (mean 163 cc). Essential aspects of our technique include a transverse cystotomy just proximal to the prostatovesical junction and use of a robotic tenotomy grasper to aid in adenoma dissection. AB - RESULTS: Mean operative time was 179 minutes (range 90-270 min), and mean estimated blood loss was 219 mL (range 50-500 mL). Mean hospital stay was 2.7 days (range 1-8 d), and the mean urethral catheterization time was 8.8 days (range 5-14 d). None of the patients needed blood transfusion. One patient had an intraoperative urinary leak after bladder closure that was managed with prolonged urethral catheterization (14 d). Histopathologic analysis confirmed benign prostatic hyperplasia (BPH) in all patients, and mean specimen weight on pathologic examination was 127 g (range 100-165 g). Mean follow-up duration was 7.2 months with all patients having a minimum of a 4-month follow-up. Significant improvements were noted in the International Prostate Symptom Score (preoperative vs postoperative 18.1 vs 5.3, p<0.001) and the maximum urine flow rate (preoperative vs postoperative 4.3 vs 19.1 mL/min, P<0.001). AB - CONCLUSIONS: Minimally invasive robot-assisted simple prostatectomy is technically feasible in patients with large volume (>100 g) BPH and is associated with significant improvements in obstructive urinary symptoms. Surgeons with robotic expertise may consider using this approach for treatment of their patients with large volume BPH. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2011.0562 PT - Clinical Trial PT - Journal Article PT - Multicenter Study ID - 22339054 [pubmed] ID - 10.1089/end.2011.0562 [doi] PP - ppublish LG - English EP - 20120410 DP - 2012 May DC - 20120427 EZ - 2012/02/21 06:00 DA - 2012/08/22 06:00 DT - 2012/02/22 06:00 YR - 2012 ED - 20120821 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22339054 <345. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19579191 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Spinoglio G AU - Summa M AU - Priora F AU - Quarati R AU - Testa S FA - Spinoglio, Giuseppe FA - Summa, Massimo FA - Priora, Fabio FA - Quarati, Raoul FA - Testa, Silvio IN - Spinoglio, Giuseppe. Department of Surgery, SS Antonio e Biagio Hospital Alessandria, Italy. TI - Robotic laparoscopic surgery with the da Vinci system: an early experience. SO - Surgical Technology International. 18:70-4, 2009 Apr AS - Surg Technol Int. 18:70-4, 2009 Apr NJ - Surgical technology international PI - Journal available in: Print PI - Citation processed from: Print JC - 9604509 IO - Surg Technol Int SB - Index Medicus CP - United States MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Female MH - Humans MH - Italy MH - *Laparoscopy/mt [Methods] MH - *Laparoscopy/sn [Statistics & Numerical Data] MH - Male MH - Middle Aged MH - Pilot Projects MH - *Robotics/mt [Methods] MH - *Robotics/sn [Statistics & Numerical Data] MH - *Surgery, Computer-Assisted/mt [Methods] MH - *Surgery, Computer-Assisted/sn [Statistics & Numerical Data] MH - Treatment Outcome MH - *Workload/sn [Statistics & Numerical Data] MH - Young Adult AB - Theoretically, robotic surgery is likely to overcome the intrinsic limitations of laparoscopic surgery, such as a view not under the direct surgeon's control, two-dimensional imaging, and limited motion of instruments. In this chapter, the preliminary experience with a robotic laparoscopic surgery system in the Surgical Department of the Alessandria Hospital, Italy, is reported. From November 2005 to August 2007, a total of 162 laparoscopic robotic operations were performed, in which robotic surgery was found to be feasible and safe. It takes a longer time than standard laparoscopy but seems able to reduce the need of a steep learning curve. IS - 1090-3941 IL - 1090-3941 PT - Clinical Trial PT - Journal Article ID - 19579191 [pubmed] PP - ppublish LG - English DP - 2009 Apr DC - 20090706 EZ - 2009/07/07 09:00 DA - 2012/08/17 06:00 DT - 2009/07/07 09:00 YR - 2009 ED - 20120816 RD - 20090706 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19579191 <346. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22059698 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Atug F AU - Kural AR AU - Tufek I AU - Srivastav S AU - Akpinar H FA - Atug, Fatih FA - Kural, Ali Riza FA - Tufek, Ilter FA - Srivastav, Sudesh FA - Akpinar, Haluk IN - Atug, Fatih. Department of Urology, Istanbul Bilim University School of Medicine, Istanbul, Turkey. fatihatug@hotmail.com TI - Anterior and posterior reconstruction technique and its impact on early return of continence after robot-assisted radical prostatectomy. SO - Journal of Endourology. 26(4):381-6, 2012 Apr AS - J Endourol. 26(4):381-6, 2012 Apr NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Demography MH - Follow-Up Studies MH - Humans MH - Logistic Models MH - Male MH - Middle Aged MH - Perioperative Care MH - *Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - *Reconstructive Surgical Procedures/mt [Methods] MH - *Robotics/mt [Methods] MH - Treatment Outcome MH - *Urinary Incontinence/et [Etiology] AB - BACKGROUND AND PURPOSE: Urinary incontinence is a significant cause of morbidity after robot-assisted radical prostatectomy (RARP). Several techniques have been developed to improve continence rates. In this study, we compared the continence rates of patients who underwent RARP with total reconstruction and without reconstruction. AB - PATIENTS AND METHODS: Between March 2005 and September 2009, 245 patients underwent RARP at our institution. The initial 120 patients (control group) underwent standard RARP without reconstruction and the last 125 patients (reconstruction group) underwent a total reconstruction technique, which included an anterior and posterior reconstruction. Patients were followed for 1, 4, 12, 24, 36, and 52 weeks after the operation. Continence was defined with strict criteria-no usage of pads and no leakage of urine. AB - RESULTS: In the reconstruction group, the continence rates at, 1, 4, 12, 24, 36, and 52 weeks postoperatively were 71%, 72%, 80%, 84%, 86%, and 91%, respectively; in the control group, the continence rates were 23%, 49%, 76%, 80%, 85%, and 88%, respectively. AB - CONCLUSION: The overall continence rates were similar in both groups at 52 weeks of follow-up. Patients in the total reconstruction group, however, had higher early continence rates compared with patients in the control group. The total reconstruction procedure is an efficient way to achieve an early return to continence. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2010.0654 PT - Clinical Trial PT - Journal Article ID - 22059698 [pubmed] ID - 10.1089/end.2010.0654 [doi] PP - ppublish LG - English EP - 20120125 DP - 2012 Apr DC - 20120406 EZ - 2011/11/09 06:00 DA - 2012/08/11 06:00 DT - 2011/11/09 06:00 YR - 2012 ED - 20120810 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22059698 <347. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22397901 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Collins SA AU - Tulikangas PK AU - O'Sullivan DM FA - Collins, Sarah A FA - Tulikangas, Paul K FA - O'Sullivan, David M IN - Collins, Sarah A. Division of Urogynecology, Department of Obstetrics and Gynecology, Hartford Hospital, University of Connecticut Health Center, Hartford, CT, USA. TI - Effect of surgical approach on physical activity and pain control after sacral colpopexy. SO - American Journal of Obstetrics & Gynecology. 206(5):438.e1-6, 2012 May AS - Am J Obstet Gynecol. 206(5):438.e1-6, 2012 May NJ - American journal of obstetrics and gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 3ni, 0370476 IO - Am. J. Obstet. Gynecol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Female MH - Gynecologic Surgical Procedures/is [Instrumentation] MH - *Gynecologic Surgical Procedures/mt [Methods] MH - Humans MH - Middle Aged MH - *Motor Activity MH - Narcotics/tu [Therapeutic Use] MH - Pain Measurement MH - Pain, Postoperative/dt [Drug Therapy] MH - *Pain, Postoperative MH - *Pelvic Organ Prolapse/su [Surgery] MH - Prospective Studies MH - Quality of Life MH - *Recovery of Function MH - *Robotics MH - Surveys and Questionnaires MH - Treatment Outcome MH - *Vagina/su [Surgery] AB - OBJECTIVE: We sought to compare recovery of activity and pain control after robotic (ROB) vs abdominal (ABD) sacral colpopexy. AB - STUDY DESIGN: Women undergoing ROB and ABD sacral colpopexy wore accelerometers for 7 days preoperatively and the first 10 days postoperatively. They completed postoperative pain diaries and Short Form-36 questionnaires before and after surgery. AB - RESULTS: At 5 days postoperatively, none of the 14 subjects in the ABD group and 4 of 28 (14.3%) in the ROB group achieved 50% total baseline activity counts (P = .283). At 10 days, 5 of 14 (35.7%) in the ABD group and 8 of 26 (30.8%) in the ROB group (P = .972) achieved 50%. Postoperative pain was similar in both groups. Short Form-36 vitality scores were lower (P = .017) after surgery in the ABD group, but not in the ROB group. AB - CONCLUSION: Women undergoing ROB vs ABD sacral colpopexy do not recover physical activity faster, and pain control is not improved. AB - Copyright © 2012 Mosby, Inc. All rights reserved. RN - 0 (Narcotics) ES - 1097-6868 IL - 0002-9378 DI - S0002-9378(12)00127-5 DO - https://dx.doi.org/10.1016/j.ajog.2012.01.036 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 22397901 [pubmed] ID - S0002-9378(12)00127-5 [pii] ID - 10.1016/j.ajog.2012.01.036 [doi] PP - ppublish PH - 2011/11/04 [received] PH - 2012/01/10 [revised] PH - 2012/01/31 [accepted] LG - English EP - 20120201 DP - 2012 May DC - 20120430 EZ - 2012/03/09 06:00 DA - 2012/07/28 06:00 DT - 2012/03/09 06:00 YR - 2012 ED - 20120727 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22397901 <348. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22221566 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Zorn KC AU - Trinh QD AU - Jeldres C AU - Schmitges J AU - Widmer H AU - Lattouf JB AU - Sammon J AU - Liberman D AU - Sun M AU - Bianchi M AU - Karakiewicz PI AU - Denis R AU - Gautam G AU - El-Hakim A FA - Zorn, Kevin C FA - Trinh, Quoc-Dien FA - Jeldres, Claudio FA - Schmitges, Jan FA - Widmer, Hugues FA - Lattouf, Jean-Baptiste FA - Sammon, Jesse FA - Liberman, Dan FA - Sun, Maxine FA - Bianchi, Marco FA - Karakiewicz, Pierre I FA - Denis, Ronald FA - Gautam, Gagan FA - El-Hakim, Assaad IN - Zorn, Kevin C. University of Montreal Hospital Center, Hopital Sacre-Coeur de Montreal, QC, Canada. TI - Prospective randomized trial of barbed polyglyconate suture to facilitate vesico-urethral anastomosis during robot-assisted radical prostatectomy: time reduction and cost benefit. SO - BJU International. 109(10):1526-32, 2012 May AS - BJU Int. 109(10):1526-32, 2012 May NJ - BJU international PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - dcu, 100886721 IO - BJU Int. SB - Index Medicus CP - England MH - Anastomosis, Surgical/ec [Economics] MH - Anastomosis, Surgical/mt [Methods] MH - Cost-Benefit Analysis MH - Equipment Design MH - Follow-Up Studies MH - Humans MH - Intraoperative Period MH - Male MH - Middle Aged MH - *Polymers MH - Prospective Studies MH - Prostatectomy/ec [Economics] MH - *Prostatectomy/mt [Methods] MH - *Robotics/ec [Economics] MH - Suture Techniques/ec [Economics] MH - *Suture Techniques/is [Instrumentation] MH - *Sutures MH - Time Factors MH - Treatment Outcome MH - *Urethra/su [Surgery] MH - *Urinary Bladder/su [Surgery] AB - UNLABELLED: Study Type - RCT (randomized trial) Level of Evidence 2b. What's known on the subject? and What does the study add? In a previous randomized controlled trial, barbed polyglyconate suture for vesico-urethral anastomosis was associated with more frequent cystogram leaks, longer mean catheterization times and greater suture costs per case. In the current randomized controlled trial, we show that barbed polyglyconate suture is associated with decreased anastomosis time, decreased need to readjust suture tension, cost reduction, and equal continence and early/late urinary complication rates. AB - OBJECTIVE: To examine the effectiveness of barbed polyglyconate suture (V-Loc 180; Covidien, Mansfield, MA, USA) compared with standard monofilament for posterior reconstruction (PR) and vesico-urethral anastomosis (VUA) during robot-assisted radical prostatectomy (RARP). AB - PATIENTS AND METHODS: A prospective randomized controlled trial was conducted in 70 consecutive RARP cases by a single surgeon (K.C.Z.). Standard VUA was performed using three 4-0 poliglecaprone 25 (Monocryl; Ethicon Endosurgery, Cincinnati, OH, USA) sutures secured with absorbable suture clips (LapraTy, Ethicon; one single 6-inch [15.2 cm] for PR and two attached 6-inch [15.2 cm] for VUA). Barbed suture VUA was performed using two 3-0 6-inch (15.2 cm) barbed polyglyconate sutures. Time to complete the suture set-up by the nursing team, anastomosis time and need to adjust suture tension were recorded. Suture-related complications, validated-questionnaire continence and cost were also examined. AB - RESULTS: Compared with a conventional reconstruction technique, there was a significant reduction in mean nurse set-up time (31 vs. 294 s; P < 0.01) and reconstruction time (13.1 vs. 20.8 min; P < 0.01) for the barbed suture technique. Need to readjust suture tension or to place additional suture clips for watertight closure was greater in the standard monofilament group than in the barbed suture group (6% vs. 24%; P= 0.03). * A cost reduction was recorded at our institution (48.05 vs. 70.25 $CAN) with the barbed suture technique. * With a mean follow-up of 6.2 months, no delayed anastomotic leak or bladder neck contracture was observed in either group. * Pad-free continence outcomes for the monofilament suture vs the barbed suture groups at 1 (64 vs. 69%, P= 0.6), 3 (76 vs. 81%, P= 0.5) and 6 months (88 vs. 92%, P= 0.7) were similar. AB - CONCLUSIONS: * Compared with standard monofilament suture, the unidirectional barbed polyglyconate suture appears to provide safe, efficient and cost-effective PR and VUA during RARP. * Use of the interlocked barbed polyglyconate suture technique prevents slippage, precluding the need for assistance, knot-tying and constant reassessment of anastomosis integrity. AB - Copyright © 2012 THE AUTHORS. BJU INTERNATIONAL © 2012 BJU INTERNATIONAL. RN - 0 (Polymers) RN - 75734-93-9 (polyglyconate) ES - 1464-410X IL - 1464-4096 DO - https://dx.doi.org/10.1111/j.1464-410X.2011.10763.x PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 22221566 [pubmed] ID - 10.1111/j.1464-410X.2011.10763.x [doi] PP - ppublish LG - English EP - 20120105 DP - 2012 May DC - 20120423 EZ - 2012/01/07 06:00 DA - 2012/07/12 06:00 DT - 2012/01/10 06:00 YR - 2012 ED - 20120711 RD - 20120423 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22221566 <349. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22546384 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hillyer SP AU - Autorino R AU - Spana G AU - Guillotreau J AU - Stein RJ AU - Haber GP AU - Kaouk JH FA - Hillyer, Shahab P FA - Autorino, Riccardo FA - Spana, Gregory FA - Guillotreau, Julien FA - Stein, Robert J FA - Haber, Georges-Pascal FA - Kaouk, Jihad H IN - Hillyer, Shahab P. Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA. TI - Perioperative outcomes of robotic-assisted partial nephrectomy in elderly patients: a matched-cohort study. CM - Comment in: J Urol. 2013 Apr;189(4):1284; PMID: 23561336 CM - Comment in: Urology. 2012 May;79(5):1067; author reply 1067; PMID: 22546385 SO - Urology. 79(5):1063-7, 2012 May AS - Urology. 79(5):1063-7, 2012 May NJ - Urology PI - Journal available in: Print PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Adult MH - Age Factors MH - Aged MH - Aged, 80 and over MH - Carcinoma, Renal Cell/pa [Pathology] MH - *Carcinoma, Renal Cell/su [Surgery] MH - Chi-Square Distribution MH - Humans MH - Kidney Neoplasms/pa [Pathology] MH - *Kidney Neoplasms/su [Surgery] MH - Middle Aged MH - Nephrectomy/ae [Adverse Effects] MH - *Nephrectomy/mt [Methods] MH - Retrospective Studies MH - Robotics MH - Treatment Outcome AB - OBJECTIVE: To compare elderly patients undergoing robotic assisted partial nephrectomy (RAPN) with a match cohort of younger patients. Investigating the benefits of minimally invasive RAPN including faster convalescence and decreased postoperative narcotic use make this an attractive option in patients with advanced age and numerous comorbidities. AB - METHODS: A retrospective review of 250 consecutive patients who underwent robotic-assisted partial nephrectomy (RAPN) for a solitary renal tumor from June 2006 to May 2010 at our institution was performed. Thirty-seven patients > 70 years (G70) who underwent 38 robotic partial nephrectomy (RPN) procedures were identified. This group was matched with 38 patients <70 years (L70) who underwent 38 RPN procedures at our institution. Functional, perioperative, and oncological outcomes of RAPN in patients > 70 years old were analyzed. AB - RESULTS: Overall, the median tumor size was 2.65 cm. Tumor characteristics, renal function, nephrometry score, and incidence of renal cancer in lesions were similar between the L70 and G70 groups. The two groups showed no differences in American Society of Anesthesiologists scores of 1-4 or Charlson comorbidity index score. Perioperative and postoperative outcomes showed no variation between L70 and G70 patients. Postoperative complications rate of 21% and 31.6% in the L70 and G70 groups, respectively, showed no difference (P < .48). There were 5 deaths, 3 of which occurred in the G70 group (8.1%) at a median of 22 months after surgery. AB - CONCLUSION: RAPN for small renal masses offers a safe alternative for patients >70 years of age, with no increase in perioperative and postoperative morbidity and mortality. Age may not be predictive of perioperative complications. AB - Copyright © 2012. Published by Elsevier Inc. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(12)00138-0 DO - https://dx.doi.org/10.1016/j.urology.2011.12.056 PT - Comparative Study PT - Journal Article ID - 22546384 [pubmed] ID - S0090-4295(12)00138-0 [pii] ID - 10.1016/j.urology.2011.12.056 [doi] PP - ppublish PH - 2011/10/11 [received] PH - 2011/12/10 [revised] PH - 2011/12/15 [accepted] LG - English DP - 2012 May DC - 20120501 EZ - 2012/05/02 06:00 DA - 2012/07/03 06:00 DT - 2012/05/02 06:00 YR - 2012 ED - 20120702 RD - 20130515 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22546384 <350. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22532102 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - De Cocker K AU - Spittaels H AU - Cardon G AU - De Bourdeaudhuij I AU - Vandelanotte C FA - De Cocker, Katrien FA - Spittaels, Heleen FA - Cardon, Greet FA - De Bourdeaudhuij, Ilse FA - Vandelanotte, Corneel IN - De Cocker, Katrien. Department of Movement and Sports Sciences, Ghent University, Watersportlaan 2, Ghent, Belgium. Katrien.DeCocker@ugent.be TI - Web-based, computer-tailored, pedometer-based physical activity advice: development, dissemination through general practice, acceptability, and preliminary efficacy in a randomized controlled trial. SO - Journal of Medical Internet Research. 14(2):e53, 2012 Apr 24 AS - J Med Internet Res. 14(2):e53, 2012 Apr 24 NJ - Journal of medical Internet research PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 100959882 IO - J. Med. Internet Res. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376513 SB - Index Medicus CP - Canada MH - Adult MH - Female MH - *General Practice MH - Humans MH - *Internet MH - Male MH - Middle Aged MH - *Motor Activity MH - *Patient Acceptance of Health Care MH - *Walking AB - BACKGROUND: Computer tailoring is a relatively innovative and promising physical activity intervention approach. However, few computer-tailored physical activity interventions in adults have provided feedback based on pedometer use. AB - OBJECTIVES: To (1) describe the development of a Web-based, pedometer-based, computer-tailored step advice intervention, (2) report on the dissemination of this tool through general practice, (3) report on its perceived acceptability, and (4) evaluate the preliminary efficacy of this tool in comparison with a standard intervention. AB - METHODS: We recruited 92 participants through general practitioners and randomly assigned them to a standard condition (receiving a pedometer-only intervention, n = 47) and a tailored condition (receiving a pedometer plus newly developed, automated, computer-tailored step advice intervention, n = 45). Step counts, self-reported data obtained via telephone interview on physical activity, time spent sitting, and body mass index were assessed at baseline and postintervention. The present sample was mostly female (54/92, 59%), highly educated (59/92, 64%), employed (65/92, 71%), and in good health (62/92, 67%). AB - RESULTS: Recruitment through general practitioners was poor (n = 107, initial response rate 107/1737, 6.2%); however, the majority of participants (50/69, 73%) believed it is useful that general practitioners help patients find ways to increase physical activity. In the tailored condition, 30/43 (70%) participants requested the computer-tailored step advice and the majority found it understandable (21/21, 100%), credible (17/18, 94%), relevant (15/18, 83%), not too long (13/18, 72%), instructive (13/18, 72%), and encouraging to increase steps (16/24, 67%). Daily step counts increased from baseline (mean 9237, SD 3749 steps/day) to postintervention (mean 11,876, SD 4574 steps/day) in the total sample (change of 2639, 95% confidence interval 105-5172; F(1 )= 5.0, P = .04). No interaction or other time effects were found. AB - CONCLUSIONS: The majority of participants in the tailored condition accepted the step advice and indicated it was useful. However, in this selected sample of adults, the tailored condition did not show superior effects compared with the standard condition. ES - 1438-8871 IL - 1438-8871 DI - v14i2e53 DO - https://dx.doi.org/10.2196/jmir.1959 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 22532102 [pubmed] ID - v14i2e53 [pii] ID - 10.2196/jmir.1959 [doi] ID - PMC3376513 [pmc] PP - epublish PH - 2011/10/05 [received] PH - 2012/01/31 [accepted] PH - 2012/01/26 [revised] LG - English EP - 20120424 DP - 2012 Apr 24 DC - 20120425 EZ - 2012/04/26 06:00 DA - 2012/06/20 06:00 DT - 2012/04/26 06:00 YR - 2012 ED - 20120619 RD - 20150225 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22532102 <351. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21924563 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Meyer C AU - Ulbricht S AU - Gross B AU - Kastel L AU - Wittrien S AU - Klein G AU - Skoeries BA AU - Rumpf HJ AU - John U FA - Meyer, Christian FA - Ulbricht, Sabina FA - Gross, Beatrice FA - Kastel, Lissy FA - Wittrien, Sabine FA - Klein, Gudrun FA - Skoeries, Britta A FA - Rumpf, Hans-Jurgen FA - John, Ulrich IN - Meyer, Christian. University of Greifswald, Institute of Epidemiology and Social Medicine, Germany. chmeyer@uni-greifswald.de TI - Adoption, reach and effectiveness of computer-based, practitioner delivered and combined smoking interventions in general medical practices: a three-arm cluster randomized trial. SO - Drug & Alcohol Dependence. 121(1-2):124-32, 2012 Feb 01 AS - Drug Alcohol Depend. 121(1-2):124-32, 2012 Feb 01 NJ - Drug and alcohol dependence PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - ebs, 7513587 IO - Drug Alcohol Depend SB - Index Medicus CP - Ireland MH - Adult MH - Aged MH - *Behavior Therapy MH - Counseling MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Primary Health Care MH - Smoking/px [Psychology] MH - *Smoking/th [Therapy] MH - *Smoking Cessation/mt [Methods] MH - *Therapy, Computer-Assisted MH - Treatment Outcome AB - BACKGROUND: Brief advice for smoking patients has not been sufficiently integrated in routine care. Computer-based interventions emerged as a time saving option that might help to exhaust the potential population impact of the general practice setting. AB - METHOD: 151 practices were randomly assigned to one of three intervention programs consisting in the delivery of: (1) brief advice by the practitioner; (2) individually tailored computer-generated letters; or (3) a combination of both interventions. We assessed three dimensions of population impact: (1) adoption, i.e., the rate of practices participating in the program; (2) reach, measured as the number of interventions provided within 7 months; (3) effectiveness, measured as smoking abstinence at 12-months follow-up. AB - RESULTS: Among the practices, 70% adopted the program with no significant differences across study groups. Treatment was provided to 3086 adult smokers. Negative binomial regression analysis revealed that the number of interventions provided was higher in practices allocated to the tailored letter and combination intervention groups by 215% (p<.01) and 127% (p=.02), respectively, compared to the brief advice intervention group. Among the patients who received the combination of both intervention, the odds of point abstinence from smoking was increased by 65% (p=.02) and 32% (p=.01) compared to the brief advice and tailored letters intervention respectively. Comparing the number of abstinent patients at follow-up revealed that the tailored letter and combination interventions were superior to the brief advice intervention. AB - CONCLUSIONS: Computer-based interventions alone or in addition to conventional practitioner-delivered advice can foster the participation of general medical practices in tobacco control. AB - Copyright © 2011 Elsevier Ireland Ltd. All rights reserved. ES - 1879-0046 IL - 0376-8716 DI - S0376-8716(11)00375-9 DO - https://dx.doi.org/10.1016/j.drugalcdep.2011.08.019 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 21924563 [pubmed] ID - S0376-8716(11)00375-9 [pii] ID - 10.1016/j.drugalcdep.2011.08.019 [doi] PP - ppublish PH - 2010/12/29 [received] PH - 2011/07/12 [revised] PH - 2011/08/19 [accepted] LG - English EP - 20110915 DP - 2012 Feb 01 DC - 20120120 EZ - 2011/09/20 06:00 DA - 2012/06/05 06:00 DT - 2011/09/20 06:00 YR - 2012 ED - 20120604 RD - 20120120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21924563 <352. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21913134 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kang J AU - Min BS AU - Park YA AU - Hur H AU - Baik SH AU - Kim NK AU - Sohn SK AU - Lee KY FA - Kang, Jeonghyun FA - Min, Byung Soh FA - Park, Yoon Ah FA - Hur, Hyuk FA - Baik, Seung Hyuk FA - Kim, Nam Kyu FA - Sohn, Seung Kook FA - Lee, Kang Young IN - Kang, Jeonghyun. Department of Surgery, Yonsei University Health System, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Korea. TI - Risk factor analysis of postoperative complications after robotic rectal cancer surgery. SO - World Journal of Surgery. 35(11):2555-62, 2011 Nov AS - World J Surg. 35(11):2555-62, 2011 Nov NJ - World journal of surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - xo8, 7704052 IO - World J Surg SB - Index Medicus CP - United States MH - *Adenocarcinoma/su [Surgery] MH - Adult MH - Aged MH - Aged, 80 and over MH - *Colectomy/mt [Methods] MH - Female MH - Humans MH - Logistic Models MH - Male MH - Middle Aged MH - Multivariate Analysis MH - *Postoperative Complications/ep [Epidemiology] MH - Prospective Studies MH - *Rectal Neoplasms/su [Surgery] MH - Risk Factors MH - *Robotics AB - BACKGROUND: The robotic system has been adopted as the new modality for minimally invasive surgery for rectal cancer. However, analysis of risk factors for complications after robotic rectal cancer surgery (RRS) has been limited. This study aimed to identify the risk factors for complications after RRS. AB - METHODS: The records of 389 consecutive patients who underwent RRS between June 2006 and October 2010 were retrieved from our prospectively collected database. AB - RESULTS: The overall complication rate was 19%. The most common complication was anastomotic leakage (7.0%), followed by voiding difficulty, intrapelvic abscess, and ileus/obstruction. Multivariate analysis revealed the following as risk factors for postoperative complications: male gender, history of previous abdominal surgery, and lower tumor level (hazard ratio [HR] = 1.8, 95% confidence interval [CI] = 1.0-3.1, p = 0.041; HR = 2.3; 95% CI = 1.2-4.6, p = 0.012; and HR = 1.9, 95% CI = 1.1-3.3, p = 0.020, respectively). With regard to pelvic septic complications, lower tumor level, large tumor size, and preoperative chemoradiation remained variables that retained their statistical significance in multivariate analysis (HR = 2.6, 95% CI = 1.1-6.1, p = 0.029; HR = 2.7, 95% CI = 1.1-6.1, p = 0.017; HR = 2.9, 95% CI = 1.3-6.5, p = 0.007, respectively). The rate of postoperative complications was not influenced by the difference in laparoscopic surgery experience or the technique of robotic surgery. AB - CONCLUSION: Surgeons should be more cautious with these patient factors to optimize the benefits of robotic rectal resection. ES - 1432-2323 IL - 0364-2313 DO - https://dx.doi.org/10.1007/s00268-011-1270-9 PT - Clinical Trial PT - Journal Article ID - 21913134 [pubmed] ID - 10.1007/s00268-011-1270-9 [doi] PP - ppublish LG - English DP - 2011 Nov DC - 20111012 EZ - 2011/09/14 06:00 DA - 2012/05/30 06:00 DT - 2011/09/14 06:00 YR - 2011 ED - 20120529 RD - 20111012 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21913134 <353. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22137540 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sebrow D AU - Lavery HJ AU - Brajtbord JS AU - Hobbs A AU - Levinson AW AU - Samadi DB FA - Sebrow, Dov FA - Lavery, Hugh J FA - Brajtbord, Jonathan S FA - Hobbs, Adele FA - Levinson, Adam W FA - Samadi, David B IN - Sebrow, Dov. Division of Robotic and Minimally Invasive Surgery, Department of Urology, Mount Sinai Medical Center, New York, New York 10022, USA. TI - Monitoring validated quality of life outcomes after prostatectomy: initial description of novel online questionnaire. CM - Comment in: Urology. 2012 Feb;79(2):319-20; PMID: 22310747 SO - Urology. 79(2):314-9, 2012 Feb AS - Urology. 79(2):314-9, 2012 Feb NJ - Urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Computer Security MH - Confidentiality MH - Cross-Sectional Studies MH - Educational Status MH - Electronic Mail/ec [Economics] MH - *Electronic Mail MH - Humans MH - Income MH - Internet/ec [Economics] MH - *Laparoscopy/px [Psychology] MH - Male MH - Patient Acceptance of Health Care MH - Patient Satisfaction MH - Pilot Projects MH - Postoperative Complications/ep [Epidemiology] MH - Postoperative Complications/et [Etiology] MH - *Postoperative Complications/px [Psychology] MH - Prostatectomy/mt [Methods] MH - *Prostatectomy/px [Psychology] MH - *Quality of Life MH - Robotics MH - Socioeconomic Factors MH - Surveys and Questionnaires/ec [Economics] MH - *Surveys and Questionnaires MH - Treatment Outcome AB - OBJECTIVES: To describe a novel, low-cost, online health-related quality of life (HRQOL) survey that allows for automated follow-up and convenient access for patients in geographically diverse locations. Clinicians and investigators have been encouraged to use validated HRQOL instruments when reporting outcomes after radical prostatectomy. AB - METHODS: The institutional review board approved our protocol and the use of a secure web site (http://www.SurveyMonkey.com) to send patients a collection of validated postprostatectomy HRQOL instruments by electronic mail. To assess compliance with the electronic mail format, a pilot study of cross-sectional surveys was sent to patients who presented for follow-up after robotic-assisted laparoscopic prostatectomy. The response data were transmitted in secure fashion in compliance with the Health Insurance Portability and Accountability Act. AB - RESULTS: After providing written informed consent, 514 patients who presented for follow-up after robotic-assisted laparoscopic prostatectomy from March 2010 to February 2011 were sent the online survey. A total of 293 patients (57%) responded, with an average age of 60 years and a median interval from surgery of 12 months. Of the respondents, 75% completed the survey within 4 days of receiving the electronic mail, with a median completion time of 15 minutes. The total survey administration costs were limited to the web site's $200 annual fee-for-service. AB - CONCLUSIONS: An online survey can be a low-cost, efficient, and confidential modality for assessing validated HRQOL outcomes in patients who undergo treatment of localized prostate cancer. This method could be especially useful for those who cannot return for follow-up because of geographic reasons. AB - Copyright © 2012 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(11)02491-5 DO - https://dx.doi.org/10.1016/j.urology.2011.08.075 PT - Clinical Trial PT - Journal Article ID - 22137540 [pubmed] ID - S0090-4295(11)02491-5 [pii] ID - 10.1016/j.urology.2011.08.075 [doi] PP - ppublish PH - 2011/05/19 [received] PH - 2011/08/10 [revised] PH - 2011/08/26 [accepted] LG - English EP - 20111202 DP - 2012 Feb DC - 20120207 EZ - 2011/12/06 06:00 DA - 2012/05/18 06:00 DT - 2011/12/06 06:00 YR - 2012 ED - 20120517 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22137540 <354. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21912876 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Collinson FJ AU - Jayne DG AU - Pigazzi A AU - Tsang C AU - Barrie JM AU - Edlin R AU - Garbett C AU - Guillou P AU - Holloway I AU - Howard H AU - Marshall H AU - McCabe C AU - Pavitt S AU - Quirke P AU - Rivers CS AU - Brown JM FA - Collinson, Fiona J FA - Jayne, David G FA - Pigazzi, Alessio FA - Tsang, Charles FA - Barrie, Jennifer M FA - Edlin, Richard FA - Garbett, Christopher FA - Guillou, Pierre FA - Holloway, Ivana FA - Howard, Helen FA - Marshall, Helen FA - McCabe, Christopher FA - Pavitt, Sue FA - Quirke, Phil FA - Rivers, Carly S FA - Brown, Julia M B IN - Collinson, Fiona J. Clinical Trials Research Unit, University of Leeds, Leeds, LS2 9JT, UK. f.j.collinson@leeds.ac.uk TI - An international, multicentre, prospective, randomised, controlled, unblinded, parallel-group trial of robotic-assisted versus standard laparoscopic surgery for the curative treatment of rectal cancer. SO - International Journal of Colorectal Disease. 27(2):233-41, 2012 Feb AS - Int J Colorectal Dis. 27(2):233-41, 2012 Feb NJ - International journal of colorectal disease PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - itf, 8607899 IO - Int J Colorectal Dis SB - Index Medicus CP - Germany MH - Adult MH - Health Care Costs MH - Humans MH - *International Cooperation MH - Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/ec [Economics] MH - Laparoscopy/es [Ethics] MH - *Laparoscopy/mt [Methods] MH - Prospective Studies MH - Quality of Life MH - Rectal Neoplasms/ec [Economics] MH - Rectal Neoplasms/pa [Pathology] MH - *Rectal Neoplasms/su [Surgery] MH - Robotics/ec [Economics] MH - Robotics/es [Ethics] MH - *Robotics/mt [Methods] MH - Treatment Outcome AB - PURPOSE: There is growing enthusiasm for robotic-assisted laparoscopic operations across many surgical specialities, including colorectal surgery, often not supported by robust clinical or cost-effectiveness data. A proper assessment of this new technology is required, prior to widespread recommendation or implementation. AB - METHODS/DESIGN: The ROLARR trial is a pan-world, prospective, randomised, controlled, unblinded, superiority trial of robotic-assisted versus standard laparoscopic surgery for the curative treatment of rectal cancer. It will investigate differences in terms of the rate of conversion to open operation, rate of pathological involvement of circumferential resection margin, 3-year local recurrence, disease-free and overall survival rates and also operative morbidity and mortality, quality of life and cost-effectiveness. The primary outcome measure is the rate of conversion to open operation. For 80% power at the 5% (two-sided) significance level, to identify a relative 50% reduction in open conversion rate (25% to 12.5%), 336 patients will be required. The target recruitment is 400 patients overall to allow loss to follow-up. Patients will be followed up at 30 days and 6 months post-operatively and then annually until 3 years after the last patient has been randomised. AB - DISCUSSION: In many centres, robotic-assisted surgery is being implemented on the basis of theoretical advantages, which have yet to be confirmed in practice. Robotic surgery is an expensive health care provision and merits robust evaluation. The ROLARR trial is a pragmatic trial aiming to provide a comprehensive evaluation of both robotic-assisted and standard laparoscopic surgery for the curative resection of rectal cancer. ES - 1432-1262 IL - 0179-1958 DO - https://dx.doi.org/10.1007/s00384-011-1313-6 PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 21912876 [pubmed] ID - 10.1007/s00384-011-1313-6 [doi] PP - ppublish PH - 2011/08/30 [accepted] GI - No: MC_G1002457 Organization: *Medical Research Council* Country: United Kingdom Organization: *Medical Research Council* Country: United Kingdom LG - English EP - 20110913 DP - 2012 Feb DC - 20120130 EZ - 2011/09/14 06:00 DA - 2012/05/17 06:00 DT - 2011/09/14 06:00 YR - 2012 ED - 20120516 RD - 20161122 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21912876 <355. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21523325 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hemal AK AU - Agarwal MM AU - Babbar P FA - Hemal, Ashok K FA - Agarwal, Mayank Mohan FA - Babbar, P IN - Hemal, Ashok K. Department of Urology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA. ahemal@wfubmc.edu TI - Impact of newer unidirectional and bidirectional barbed suture on vesicourethral anastomosis during robot-assisted radical prostatectomy and its comparison with polyglecaprone-25 suture: an initial experience. SO - International Urology & Nephrology. 44(1):125-32, 2012 Feb AS - Int Urol Nephrol. 44(1):125-32, 2012 Feb NJ - International urology and nephrology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - guq, 0262521 IO - Int Urol Nephrol SB - Index Medicus CP - Netherlands MH - Adult MH - Aged MH - Anastomosis, Surgical/ae [Adverse Effects] MH - Dioxanes MH - Equipment Design MH - Humans MH - Laparoscopy/is [Instrumentation] MH - Length of Stay MH - Male MH - Middle Aged MH - Pilot Projects MH - Polyesters MH - Polymers MH - *Prostatectomy/is [Instrumentation] MH - *Prostatic Neoplasms/su [Surgery] MH - Robotics MH - Statistics, Nonparametric MH - *Sutures MH - Time Factors MH - *Urethra/su [Surgery] MH - *Urinary Bladder/su [Surgery] AB - OBJECTIVE: To evaluate impact of unidirectional barbed suture on vesicourethral anastomosis (VUA) during robot-assisted radical prostatectomy (RARP) and its comparison with Polyglecaprone-25 suture. AB - PATIENTS AND METHODS: The study was initiated as pilot study; the participants were grouped into three based on the suture material used for VUA, i.e., monofilament Polyglecaprone-25 (group 1), unidirectional barbed Glycolic acid-trimethylene carbonate (group 2), and bidirectional barbed Polyglycolic acid-polycaprolactone (group 3), respectively. Group 1 was included retrospectively and the latter two prospectively. All cases were operated upon by the same surgeon, proficient in RARP. Patient-demographics, intraoperative and peri-operative data were collected. Our technique of mucosa-to-mucosa VUA is carried out in a choreographed manner using unibarbed suture. AB - RESULTS: Fifty-five patients were included; 25 each in group 1 and 2. The group 3 was prematurely closed after 5 cases due to perceived inappropriateness of needle characteristics of the suture material. Therefore, the statistical analysis was performed between group 1 and 2 only. Preoperative characteristics including age, PSA, clinical stage, and biopsy grade were similar between the groups. The anastomosis time was significantly less in group 2 (8.4 +/- 1.7 min vs. 14.3 +/- 4.8 min; P = 0.0001; t test). Postoperative hospital stay was less in group 2 (2.7 +/- 1.1 days vs. 1.9 +/- 0.8 days; P = 0.023; Mann-Whitney U). None of the patient had presented with urinary leaks, urinary retention, or anastomotic strictures at follow-up of 6 months. AB - CONCLUSION: VUA with unidirectional barbed suture is safe and takes less time compared to monofilament suture as repeated cinching; help of assistance and knot tying are not required by virtue of its self-retaining characteristics. RN - 0 (Dioxanes) RN - 0 (Polyesters) RN - 0 (Polymers) RN - 41706-81-4 (glycolide E-caprolactone copolymer) RN - 75734-93-9 (polyglyconate) ES - 1573-2584 IL - 0301-1623 DO - https://dx.doi.org/10.1007/s11255-011-9967-0 PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article ID - 21523325 [pubmed] ID - 10.1007/s11255-011-9967-0 [doi] PP - ppublish PH - 2011/03/13 [received] PH - 2011/04/06 [accepted] LG - English EP - 20110427 DP - 2012 Feb DC - 20120110 EZ - 2011/04/28 06:00 DA - 2012/05/17 06:00 DT - 2011/04/28 06:00 YR - 2012 ED - 20120516 RD - 20120110 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21523325 <356. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22424002 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hoffmann U AU - Truong QA AU - Fleg JL AU - Goehler A AU - Gazelle S AU - Wiviott S AU - Lee H AU - Udelson JE AU - Schoenfeld D AU - ROMICAT II FA - Hoffmann, Udo FA - Truong, Quynh A FA - Fleg, Jerome L FA - Goehler, Alexander FA - Gazelle, Scott FA - Wiviott, Stephen FA - Lee, Hang FA - Udelson, James E FA - Schoenfeld, David FA - ROMICAT II IN - Hoffmann, Udo. Cardiac MR PET CT Program, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA; Division of Cardiology, Massachusetts General Hospital, Boston, MA 02114, USA. uhoffmann@partners.org IR - Hauser T IR - Pope JH IR - Chou E IR - Woodard P IR - Weiner S IR - White C IR - Nagurney JT IR - Peacock F IR - Pang PS IR - Mikati I IR - Pierchala L IR - Martin E IR - Peacock WF IR - Flamm SD IR - Schoenhagen P IR - Bolen M IR - Gaul E IR - Mullins ME IR - Rasalingham R IR - Harring S IR - Lesniak D IR - Barnewolt BA IR - Kalajian S IR - Do BK IR - Zychowicz S IR - Owens L IR - Vaghasia U IR - Chappell A IR - Woldetensay H IR - Byrne R IR - Brown D IR - Gaggin HN IR - Ghoshhajra B IR - Bayley J IR - Lumish H IR - Cheng TC IR - Parry BA IR - Moore C IR - Blank FS IR - Barus R IR - Coute R IR - Schmidt T IR - Johnston D IR - Waring J IR - Shapiro N IR - Bierhals A IR - Javidan-Nejad C IR - Bond M IR - Fardanesh KL TI - Design of the Rule Out Myocardial Ischemia/Infarction Using Computer Assisted Tomography: a multicenter randomized comparative effectiveness trial of cardiac computed tomography versus alternative triage strategies in patients with acute chest pain in the emergency department. SO - American Heart Journal. 163(3):330-8, 338.e1, 2012 Mar AS - Am Heart J. 163(3):330-8, 338.e1, 2012 Mar NJ - American heart journal PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 0370465 IO - Am. Heart J. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736358 OI - Source: NLM. NIHMS496247 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Acute Disease MH - Adult MH - Aged MH - *Chest Pain/di [Diagnosis] MH - Chest Pain/et [Etiology] MH - Diagnosis, Differential MH - Electrocardiography MH - *Emergency Service, Hospital MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/co [Complications] MH - *Myocardial Infarction/di [Diagnosis] MH - Reproducibility of Results MH - Retrospective Studies MH - Sensitivity and Specificity MH - *Tomography, X-Ray Computed/mt [Methods] MH - *Triage/mt [Methods] AB - Although early cardiac computed tomographic angiography (CCTA) might improve the management of emergency department (ED) patients with acute chest pain, it could also result in increased testing, costs, and radiation exposure. ROMICAT II was a randomized comparative effectiveness trial enrolling patients 40 to 74 years old without known coronary artery disease who presented to the ED with chest pain but without ischemic electrocardiographic (ECG) changes or elevated initial troponin and who required further risk stratification. Overall, 1000 patients at 9 sites within the United States were randomized to either CCTA as the first diagnostic test following serial biomarkers or to standard of care, which included no testing or functional testing such as exercise ECG, stress radionuclide imaging, or stress echocardiography. Test results were provided to ED physicians, yet patient management was not driven by a study protocol in either arm. Data were collected on diagnostic testing, cardiac events, and cost of medical care for the index hospitalization and during the following 28 days. The primary end point was length of hospital stay. Secondary end points were cumulative radiation exposure, resource utilization, and costs of competing strategies. Tertiary end points were institutional, physician, and patient characteristics associated with primary and secondary outcomes. Rate of missed acute coronary syndrome within 28 days was the safety end point. The ROMICAT II will provide rigorous data on whether CCTA is more efficient than standard of care in the management of patients with acute chest pain at intermediate risk for acute coronary syndrome. AB - Copyright A© 2012 Mosby, Inc. All rights reserved. ES - 1097-6744 IL - 0002-8703 DI - S0002-8703(12)00075-0 DO - https://dx.doi.org/10.1016/j.ahj.2012.01.028 PT - Clinical Trial PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, N.I.H., Extramural ID - 22424002 [pubmed] ID - S0002-8703(12)00075-0 [pii] ID - 10.1016/j.ahj.2012.01.028 [doi] ID - PMC3736358 [pmc] ID - NIHMS496247 [mid] PP - ppublish PH - 2012/01/27 [received] PH - 2012/01/27 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01084239 SL - https://clinicaltrials.gov/search/term=NCT01084239 GI - No: U01 HL092040 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30HL093896 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K23HL098370 Organization: (HL) *NHLBI NIH HHS* Country: United States No: U01HL092040 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30 HL093806 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K24 HL113128 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K23 HL098370 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English EP - 20120222 DP - 2012 Mar DC - 20120319 EZ - 2012/03/20 06:00 DA - 2012/05/16 06:00 DT - 2012/03/20 06:00 YR - 2012 ED - 20120515 RD - 20161215 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=22424002 <357. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22424002 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hoffmann U AU - Truong QA AU - Fleg JL AU - Goehler A AU - Gazelle S AU - Wiviott S AU - Lee H AU - Udelson JE AU - Schoenfeld D AU - ROMICAT II FA - Hoffmann, Udo FA - Truong, Quynh A FA - Fleg, Jerome L FA - Goehler, Alexander FA - Gazelle, Scott FA - Wiviott, Stephen FA - Lee, Hang FA - Udelson, James E FA - Schoenfeld, David FA - ROMICAT II IN - Hoffmann, Udo. Cardiac MR PET CT Program, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA; Division of Cardiology, Massachusetts General Hospital, Boston, MA 02114, USA. uhoffmann@partners.org IR - Hauser T IR - Pope JH IR - Chou E IR - Woodard P IR - Weiner S IR - White C IR - Nagurney JT IR - Peacock F IR - Pang PS IR - Mikati I IR - Pierchala L IR - Martin E IR - Peacock WF IR - Flamm SD IR - Schoenhagen P IR - Bolen M IR - Gaul E IR - Mullins ME IR - Rasalingham R IR - Harring S IR - Lesniak D IR - Barnewolt BA IR - Kalajian S IR - Do BK IR - Zychowicz S IR - Owens L IR - Vaghasia U IR - Chappell A IR - Woldetensay H IR - Byrne R IR - Brown D IR - Gaggin HN IR - Ghoshhajra B IR - Bayley J IR - Lumish H IR - Cheng TC IR - Parry BA IR - Moore C IR - Blank FS IR - Barus R IR - Coute R IR - Schmidt T IR - Johnston D IR - Waring J IR - Shapiro N IR - Bierhals A IR - Javidan-Nejad C IR - Bond M IR - Fardanesh KL TI - Design of the Rule Out Myocardial Ischemia/Infarction Using Computer Assisted Tomography: a multicenter randomized comparative effectiveness trial of cardiac computed tomography versus alternative triage strategies in patients with acute chest pain in the emergency department. SO - American Heart Journal. 163(3):330-8, 338.e1, 2012 Mar AS - Am Heart J. 163(3):330-8, 338.e1, 2012 Mar NJ - American heart journal PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 0370465 IO - Am. Heart J. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736358 OI - Source: NLM. NIHMS496247 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Acute Disease MH - Adult MH - Aged MH - *Chest Pain/di [Diagnosis] MH - Chest Pain/et [Etiology] MH - Diagnosis, Differential MH - Electrocardiography MH - *Emergency Service, Hospital MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/co [Complications] MH - *Myocardial Infarction/di [Diagnosis] MH - Reproducibility of Results MH - Retrospective Studies MH - Sensitivity and Specificity MH - *Tomography, X-Ray Computed/mt [Methods] MH - *Triage/mt [Methods] AB - Although early cardiac computed tomographic angiography (CCTA) might improve the management of emergency department (ED) patients with acute chest pain, it could also result in increased testing, costs, and radiation exposure. ROMICAT II was a randomized comparative effectiveness trial enrolling patients 40 to 74 years old without known coronary artery disease who presented to the ED with chest pain but without ischemic electrocardiographic (ECG) changes or elevated initial troponin and who required further risk stratification. Overall, 1000 patients at 9 sites within the United States were randomized to either CCTA as the first diagnostic test following serial biomarkers or to standard of care, which included no testing or functional testing such as exercise ECG, stress radionuclide imaging, or stress echocardiography. Test results were provided to ED physicians, yet patient management was not driven by a study protocol in either arm. Data were collected on diagnostic testing, cardiac events, and cost of medical care for the index hospitalization and during the following 28 days. The primary end point was length of hospital stay. Secondary end points were cumulative radiation exposure, resource utilization, and costs of competing strategies. Tertiary end points were institutional, physician, and patient characteristics associated with primary and secondary outcomes. Rate of missed acute coronary syndrome within 28 days was the safety end point. The ROMICAT II will provide rigorous data on whether CCTA is more efficient than standard of care in the management of patients with acute chest pain at intermediate risk for acute coronary syndrome. AB - Copyright A© 2012 Mosby, Inc. All rights reserved. ES - 1097-6744 IL - 0002-8703 DI - S0002-8703(12)00075-0 DO - https://dx.doi.org/10.1016/j.ahj.2012.01.028 PT - Clinical Trial PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, N.I.H., Extramural ID - 22424002 [pubmed] ID - S0002-8703(12)00075-0 [pii] ID - 10.1016/j.ahj.2012.01.028 [doi] ID - PMC3736358 [pmc] ID - NIHMS496247 [mid] PP - ppublish PH - 2012/01/27 [received] PH - 2012/01/27 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01084239 SA - ClinicalTrials.gov/NCT01084239 SL - https://clinicaltrials.gov/search/term=NCT01084239 SL - https://clinicaltrials.gov/search/term=NCT01084239 GI - No: U01 HL092040 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30HL093896 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K23HL098370 Organization: (HL) *NHLBI NIH HHS* Country: United States No: U01HL092040 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30 HL093806 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K24 HL113128 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K23 HL098370 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English EP - 20120222 DP - 2012 Mar DC - 20120319 EZ - 2012/03/20 06:00 DA - 2012/05/16 06:00 DT - 2012/03/20 06:00 YR - 2012 ED - 20120515 RD - 20161206 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22424002 <358. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22131088 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Uyama I AU - Kanaya S AU - Ishida Y AU - Inaba K AU - Suda K AU - Satoh S FA - Uyama, Ichiro FA - Kanaya, Seiichiro FA - Ishida, Yoshinori FA - Inaba, Kazuki FA - Suda, Koichi FA - Satoh, Seiji IN - Uyama, Ichiro. Department of Surgery, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan. iuyama@fujita-hu.ac.jp TI - Novel integrated robotic approach for suprapancreatic D2 nodal dissection for treating gastric cancer: technique and initial experience. SO - World Journal of Surgery. 36(2):331-7, 2012 Feb AS - World J Surg. 36(2):331-7, 2012 Feb NJ - World journal of surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - xo8, 7704052 IO - World J Surg SB - Index Medicus CP - United States MH - *Adenocarcinoma/su [Surgery] MH - Aged MH - Feasibility Studies MH - Female MH - Gastrectomy/is [Instrumentation] MH - Gastrectomy/mt [Methods] MH - *Gastrectomy MH - *Gastroenterostomy MH - Humans MH - Laparoscopy/is [Instrumentation] MH - *Laparoscopy/mt [Methods] MH - Learning Curve MH - Lymph Node Excision/is [Instrumentation] MH - *Lymph Node Excision/mt [Methods] MH - Male MH - Middle Aged MH - Pancreas MH - Prospective Studies MH - *Robotics MH - *Stomach Neoplasms/su [Surgery] MH - Treatment Outcome AB - BACKGROUND: Robotic surgery for the treatment of gastric cancer has been reported, but the technique is not yet established. The objective of this study was to assess the feasibility and safety of our novel integrated procedure for robotic suprapancreatic D2 nodal dissection during distal gastrectomy. AB - METHODS: At our hospital from January 2009 to December 2010, a total of 25 consecutive cases of gastric cancer were treated by robotic distal gastrectomy with intracorporeal Billroth I reconstruction. These patients were enrolled in a prospective study to assess the safety and feasibility of robotic distal gastrectomy with nodal dissection by our novel integrated approach, which consists of three elements: arm formation, the surgical approach, a cutting device. To evaluate the learning curves involved in this approach, clinicopathologic features and surgical outcomes were compared between the initial (n = 12) and late (n = 13) phases. AB - RESULTS: All operations were completed without the need for open or conventional laparoscopic surgery. The mean operating time was 361 +/- 58.1 min (range 258-419 min), and blood loss recorded was 51.8 +/- 38.2 ml (range 4-123 ml). The median number of retrieved lymph nodes was 44.3 +/- 18.4 (range 26-95). R0 resection was accomplished in all cases. There were no deaths or complications related to pancreatic damage. Operating time and surgeon console time for the late phase were significantly shorter than those for the initial phase. AB - CONCLUSIONS: Our novel robotic approach for D2 nodal dissection in gastric cancer is feasible and safe. ES - 1432-2323 IL - 0364-2313 DO - https://dx.doi.org/10.1007/s00268-011-1352-8 PT - Clinical Trial PT - Journal Article ID - 22131088 [pubmed] ID - 10.1007/s00268-011-1352-8 [doi] PP - ppublish LG - English DP - 2012 Feb DC - 20120111 EZ - 2011/12/02 06:00 DA - 2012/05/15 06:00 DT - 2011/12/02 06:00 YR - 2012 ED - 20120514 RD - 20120111 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22131088 <359. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22453316 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - McNanley A AU - Perevich M AU - Glantz C AU - Duecy EE AU - Flynn MK AU - Buchsbaum G FA - McNanley, Anna FA - Perevich, Mare FA - Glantz, Chris FA - Duecy, Erin E FA - Flynn, Michael K FA - Buchsbaum, Gunhilde IN - McNanley, Anna. Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY, USA. mena@mac.com TI - Bowel function after minimally invasive urogynecologic surgery: a prospective randomized controlled trial. SO - Female Pelvic Medicine & Reconstructive Surgery. 18(2):82-5, 2012 Mar-Apr AS - Female pelvic med. reconstr. surg.. 18(2):82-5, 2012 Mar-Apr NJ - Female pelvic medicine & reconstructive surgery PI - Journal available in: Print PI - Citation processed from: Print JC - 101528690 IO - Female Pelvic Med Reconstr Surg SB - Index Medicus CP - United States MH - Aged MH - *Analgesia, Patient-Controlled MH - Analgesics/ad [Administration & Dosage] MH - Cathartics/ad [Administration & Dosage] MH - Constipation/dt [Drug Therapy] MH - Constipation/et [Etiology] MH - Constipation/pp [Physiopathology] MH - *Constipation MH - Dioctyl Sulfosuccinic Acid/ad [Administration & Dosage] MH - Female MH - *Gastrointestinal Motility/de [Drug Effects] MH - Humans MH - Laxatives/ad [Administration & Dosage] MH - Middle Aged MH - Minimally Invasive Surgical Procedures/ae [Adverse Effects] MH - Minimally Invasive Surgical Procedures/mt [Methods] MH - Nonprescription Drugs/ad [Administration & Dosage] MH - Outcome Assessment (Health Care) MH - Pain Measurement MH - Pain, Postoperative/di [Diagnosis] MH - Pain, Postoperative/dt [Drug Therapy] MH - Pain, Postoperative/et [Etiology] MH - Pain, Postoperative/pp [Physiopathology] MH - *Pain, Postoperative MH - *Postoperative Complications/di [Diagnosis] MH - Postoperative Complications/dt [Drug Therapy] MH - Postoperative Complications/pp [Physiopathology] MH - Postoperative Period MH - Risk Factors MH - Time Factors MH - Treatment Outcome MH - *Urogenital Surgical Procedures/ae [Adverse Effects] MH - Urogenital Surgical Procedures/mt [Methods] AB - OBJECTIVES: The goals of this study were to assess the effect of a standardized postoperative bowel regimen of over-the-counter medications on (1) time to first bowel movement (BM) and (2) pain level associated with first BM in subjects undergoing minimally invasive urogynecologic surgery. AB - METHODS: Eligible patients scheduled to undergo minimally invasive urogynecologic surgery were offered participation. Enrolled subjects were randomized by computerized schedule. Demographic and perioperative data were collected. Subjects completed a validated questionnaire preoperatively and postoperatively assessing preexisting constipation, frequency and consistency of bowel movements, use of pain medications, mean daily pain level (using visual analog scale), stool consistency, and pain associated with first postoperative bowel movement. The control group was instructed to take docusate sodium twice daily postoperatively. The treatment group took docusate sodium plus Miralax, fiber wafers, and bisacodyl suppositories as directed by protocol. Wilcoxon or t testing was used to compare continuous variables; chi testing was used for categorical relationships, and backward-elimination multiple regression was used to assess independent effects. AB - RESULTS: Seventy-two subjects were enrolled and randomized. Twelve subjects withdrew, leaving 60 (30 per group) completing the study. There were no statistically significant differences between groups in baseline characteristics. Mean (SD) age was 63 (9) years for the control group and 58 (10) for the study group (P = 0.06). Mean pelvic organ prolapse stage was III in each group. The mean (SD) operating room time was 198 (65) minutes for the controls and 216 (74) for the study subjects. Sixty-five percent underwent robot-assisted surgery (50% hysterectomy and 63% sacrocolpopexy). Ninety-eight percent of surgeries were performed under general anesthesia.Before adjustment, the mean (SD) time to first BM was 77 (24) hours in controls versus 64 (21) in the study patients (P = 0.03). Using multiple regression, baseline frequency of defecation (1-2 BMs/wk) was directly associated with the time to first BM (added 25.2 hours; P = 0.009) and being in the study group was inversely associated (first BM, 11.7 hours sooner; P = 0.04). No other variables were retained.There was no difference in pain associated with first postoperative BM (visual analog scale, 3.6 (3.2) vs 3.7 (2.8); P = 0.98), but those with prior complaints of vaginal or rectal splinting had higher pain scores (1.9 and 2.8 points higher, respectively; P = 0.04 for both). There was a trend toward higher pain scores with higher postoperative daily narcotic intake (P = 0.06). No other variables were retained.There was a significant difference in recorded compliance between control versus study regimens (94% vs 81%, respectively; P = 0.002). AB - CONCLUSIONS: Mean time to first postoperative BM after minimally invasive urogynecologic surgery is more than 3.5 days with use of docusate sodium alone and is only slightly shorter when combination therapy is used. First BM after surgery is considered to be painful despite the use of medications. Future studies targeting postoperative discomfort/pain with defecation could target preoperative bowel regimens or more aggressive postoperative interventions. Regimens should remain simple to increase compliance. RN - 0 (Analgesics) RN - 0 (Cathartics) RN - 0 (Laxatives) RN - 0 (Nonprescription Drugs) RN - 10041-19-7 (Dioctyl Sulfosuccinic Acid) IS - 2151-8378 IL - 2151-8378 DI - 01436319-201203000-00004 DO - https://dx.doi.org/10.1097/SPV.0b013e3182455529 PT - Journal Article PT - Randomized Controlled Trial ID - 22453316 [pubmed] ID - 10.1097/SPV.0b013e3182455529 [doi] ID - 01436319-201203000-00004 [pii] PP - ppublish LG - English DP - 2012 Mar-Apr DC - 20120328 EZ - 2012/03/29 06:00 DA - 2012/05/09 06:00 DT - 2012/03/29 06:00 YR - 2012 ED - 20120508 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22453316 <360. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21779771 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Marengo F AU - Larrain D AU - Babilonti L AU - Spinillo A FA - Marengo, Francesca FA - Larrain, Demetrio FA - Babilonti, Luciana FA - Spinillo, Arsenio IN - Marengo, Francesca. Department of Obstetrics and Gynecology, IRCCS Fondazione-Policlinico San Matteo, University of Pavia, Pavia, Italy. francescamarengo80@gmail.com TI - Learning experience using the double-console da Vinci surgical system in gynecology: a prospective cohort study in a University hospital. SO - Archives of Gynecology & Obstetrics. 285(2):441-5, 2012 Feb AS - Arch Gynecol Obstet. 285(2):441-5, 2012 Feb NJ - Archives of gynecology and obstetrics PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 6ys, 8710213 IO - Arch. Gynecol. Obstet. SB - Index Medicus CP - Germany MH - Adult MH - Blood Loss, Surgical MH - Female MH - *Genital Diseases, Female/su [Surgery] MH - Hematoma/et [Etiology] MH - Hernia/et [Etiology] MH - Hospitals, University MH - Humans MH - Ischemic Attack, Transient/et [Etiology] MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy/ed [Education] MH - *Learning Curve MH - Length of Stay MH - Middle Aged MH - Prospective Studies MH - *Robotics/ed [Education] MH - Time Factors AB - PURPOSE: To report our preliminary experience with robotic-assisted laparoscopy in a variety of gynecological surgeries in a teaching hospital. AB - METHOD: A total of 33 patients who underwent robotic-assisted laparoscopic procedures for gynecological diseases were included in the study. All surgeries were performed using the double-console da Vinci surgical system. Patient's demographics, surgical procedures, operative time, perioperative complications, conversion rate, hospital stay and estimated blood loss were prospectively collected. AB - RESULTS: All procedures were completed robotically except three (9%): two cases were converted to laparotomy and one case was converted to vaginal surgery. The mean age was 47 +/- 11 and mean BMI was 23 kg/m2. Mean time taken for docking the robot was 22 min. Mean operative time was 152 min. Mean anesthesia time was 196 min. Mean hemoglobin drop was 2 g/dL. Four complications occurred: one transitory ischemic attack, one port-site hernia managed through trocar incision, one periumbilical hematoma managed conservatively and one vaginal cuff hematoma who required laparoscopy. The mean hospital stay was 4 days. AB - CONCLUSION: With the use of robotic technology, surgeons are able to offer minimally invasive surgery to a larger percentage of patients. Double console system seems a promising tool in surgical education, improving both resident training and participation in surgeries. A shorter adaption to robotics could be expected in teams with previous experience with standard laparoscopy, however, a stepwise start with simpler cases is the key to achieve a safe adaption to robotic surgery. ES - 1432-0711 IL - 0932-0067 DO - https://dx.doi.org/10.1007/s00404-011-2005-8 PT - Journal Article ID - 21779771 [pubmed] ID - 10.1007/s00404-011-2005-8 [doi] PP - ppublish PH - 2010/12/28 [received] PH - 2011/07/08 [accepted] LG - English EP - 20110722 DP - 2012 Feb DC - 20120113 EZ - 2011/07/23 06:00 DA - 2012/05/09 06:00 DT - 2011/07/23 06:00 YR - 2012 ED - 20120507 RD - 20120113 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21779771 <361. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21815823 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Gumus E AU - Boylu U AU - Turan T AU - Onol FF FA - Gumus, Eyup FA - Boylu, Ugur FA - Turan, Turgay FA - Onol, Fikret Fatih IN - Gumus, Eyup. Department of Urology, Umraniye Teaching Hospital, Istanbul, Turkey. TI - The learning curve of robot-assisted radical prostatectomy. SO - Journal of Endourology. 25(10):1633-7, 2011 Oct AS - J Endourol. 25(10):1633-7, 2011 Oct NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Demography MH - Humans MH - *Learning Curve MH - Male MH - Middle Aged MH - Preoperative Care MH - *Prostatectomy/ed [Education] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/su [Surgery] MH - *Robotics/ed [Education] MH - Time Factors MH - Treatment Outcome AB - PURPOSE: To evaluate the learning curve of a surgeon with no previous laparoscopy experience in performing robot-assisted radical prostatectomy (RARP). AB - PATIENTS AND METHODS: A total of 120 patients with a 1-year follow-up after RARP were included to the study prospectively. Patients were grouped as the first, second, and third 40 patients. Surgical, oncologic, and functional outcomes were compared among groups. Analysis of variance, chi-square, and Kruskal-Wallis test were used for statistical analysis. AB - RESULTS: All groups were similar with respect to age, prostate-specific antigen level, body mass index, Gleason score, and distribution of the clinical stage. The operative time was 182 minutes for group 1, 168 minutes for group 2, and 139 minutes for group 3 (P=0.01). Individual times of various stages of the procedure (dissection of the seminal vesicles, entering the extraperitoneal space and dissection of the endopelvic fascia, incision of the bladder neck, division of the prostatic pedicles and preservation of the neurovascular bundle, and urethrovesical anastomosis) decreased significantly over time. Estimated blood loss was 287mL for group 1 238mL for group 2, and 170mL for group 3 (P=0.04). The length of stay was 5.1 days for group 1, 4.0 days for group 2, and 3.1 days for group 3 (P=0.005). Positive surgical margin rates were 22% (9) for group 1, 17% (7) for group 2, and 6% (2) for group 3 (P=0.03). While seven patients in group 1 and two patients in group 2 had biochemical recurrence, no patient in group 3 had biochemical recurrence (P=0.04). Continence rates at 12 months were 72.5%, 85%, and 92.5% in groups 1, 2, and 3, respectively (P=0.01). Potency rates at 12 months for groups 1, 2, and 3 were 60.5%, 66.7%, and 76.6%, respectively (P=0.03). AB - CONCLUSION: Surgical, oncologic, and functional outcomes of RARP improve with increasing experience. Outcomes similar to the published series by high-volume centers could be achieved after 80 to 120 RARP cases. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2011.0071 PT - Clinical Trial PT - Journal Article ID - 21815823 [pubmed] ID - 10.1089/end.2011.0071 [doi] PP - ppublish LG - English EP - 20110804 DP - 2011 Oct DC - 20111006 EZ - 2011/08/06 06:00 DA - 2012/04/17 06:00 DT - 2011/08/06 06:00 YR - 2011 ED - 20120416 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21815823 <362. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22137513 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Wang G AU - Gao C AU - Zhou Q AU - Chen T AU - Wang Y AU - Wang J AU - Li J FA - Wang, Gang FA - Gao, Changqing FA - Zhou, Qi FA - Chen, Tingting FA - Wang, Yao FA - Wang, Jiali FA - Li, Jiachun IN - Wang, Gang. Department of Cardiovascular Surgery and PLA Institute of Cardiac Surgery, General Hospital of PLA, Beijing 100853, China. beijing-baoding@sohu.com TI - Anesthesia management of totally endoscopic atrial septal defect repair with a robotic surgical system. SO - Journal of Clinical Anesthesia. 23(8):621-5, 2011 Dec AS - J Clin Anesth. 23(8):621-5, 2011 Dec NJ - Journal of clinical anesthesia PI - Journal available in: Print PI - Citation processed from: Internet JC - an9, 8812166 IO - J Clin Anesth SB - Index Medicus CP - United States MH - Adolescent MH - Adult MH - Aged MH - *Anesthesia, General/mt [Methods] MH - Cardiopulmonary Bypass/mt [Methods] MH - *Endoscopy/mt [Methods] MH - Female MH - *Heart Septal Defects, Atrial/su [Surgery] MH - Hemodynamics MH - Hospitals, Military MH - Humans MH - Hypotension/et [Etiology] MH - Hypoxia/et [Etiology] MH - Intensive Care Units MH - Intubation, Intratracheal/mt [Methods] MH - Length of Stay MH - Male MH - Middle Aged MH - Oxygen/me [Metabolism] MH - Pneumothorax, Artificial/mt [Methods] MH - Respiration, Artificial/mt [Methods] MH - *Robotics MH - Time Factors MH - Ultrasonography, Interventional/mt [Methods] MH - Young Adult AB - STUDY OBJECTIVE: To investigate anesthetic techniques for robot-assisted endoscopic atrial septal defect (ASD) repair. AB - DESIGN: Clinical observational study. AB - SETTING: Operating room of a general military hospital. AB - PATIENTS: 56 adult, ASA physical status 1 and 2 patients undergoing elective general anesthesia. AB - INTERVENTIONS: After induction of general anesthesia, a left-sided, double-lumen endotracheal tube was positioned to allow single left-lung ventilation and contralateral CO(2) pneumothorax (capnothorax). With ultrasound guidance, peripheral cardiopulmonary bypass (CPB) catheters were placed. AB - MEASUREMENTS AND MAIN RESULTS: All patients tolerated single left-lung ventilation before CPB; however, hypoxia (oxygen saturation < 90%) occurred in 11 (19.6%) patients post-CPB, which required treatment with continuous positive airway pressure. Fifteen (26.8%) patients had hypotension secondary to capnothorax, which was treated with transfusion and vasopressors. Aortic cross-clamp time was 43.6 +/- 11.2 minutes, and CPB time was 106.7 +/- 12.4 minutes. The median intensive care unit stay was 21 hours and postoperative hospital stay was 4 to 7 days. AB - CONCLUSIONS: The key issue for anesthetic management of robot-assisted totally endoscopic ASD repair is maintaining stable hemodynamics and oxygenation, especially during one-lung ventilation and capnothorax. AB - Copyright © 2011 Elsevier Inc. All rights reserved. RN - S88TT14065 (Oxygen) ES - 1873-4529 IL - 0952-8180 DI - S0952-8180(11)00320-5 DO - https://dx.doi.org/10.1016/j.jclinane.2011.04.005 PT - Clinical Trial PT - Journal Article ID - 22137513 [pubmed] ID - S0952-8180(11)00320-5 [pii] ID - 10.1016/j.jclinane.2011.04.005 [doi] PP - ppublish PH - 2009/05/19 [received] PH - 2011/03/22 [revised] PH - 2011/04/20 [accepted] LG - English DP - 2011 Dec DC - 20111205 EZ - 2011/12/06 06:00 DA - 2012/04/06 06:00 DT - 2011/12/06 06:00 YR - 2011 ED - 20120405 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22137513 <363. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22228169 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Park IJ AU - You YN AU - Schlette E AU - Nguyen S AU - Skibber JM AU - Rodriguez-Bigas MA AU - Chang GJ FA - Park, In Ja FA - You, Y Nancy FA - Schlette, Erika FA - Nguyen, Sa FA - Skibber, John M FA - Rodriguez-Bigas, Miguel A FA - Chang, George J IN - Park, In Ja. Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Houston, TC 77230, USA. TI - Reverse-hybrid robotic mesorectal excision for rectal cancer. SO - Diseases of the Colon & Rectum. 55(2):228-33, 2012 Feb AS - Dis Colon Rectum. 55(2):228-33, 2012 Feb NJ - Diseases of the colon and rectum PI - Journal available in: Print PI - Citation processed from: Internet JC - eab, 0372764 IO - Dis. Colon Rectum PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546550 OI - Source: NLM. NIHMS374946 SB - Index Medicus CP - United States MH - *Adenocarcinoma/su [Surgery] MH - Aged MH - Female MH - Humans MH - Laparoscopy/mt [Methods] MH - *Lymph Node Excision/mt [Methods] MH - Male MH - Middle Aged MH - Minimally Invasive Surgical Procedures/mt [Methods] MH - Postoperative Complications MH - Prospective Studies MH - *Rectal Neoplasms/su [Surgery] MH - *Rectum/su [Surgery] MH - *Robotics MH - Time Factors MH - Treatment Outcome AB - PURPOSE: The robotic system offers potential technical advantages over laparoscopy for total mesorectal excision with radical lymphadenectomy for rectal cancer. However, the requirement for fixed docking limits its utility when the working volume is large or patient repositioning is required. The purpose of this study was to evaluate short-term outcomes associated with a novel setup to perform total mesorectal excision and radical lymphadenectomy for rectal cancer by the use of a "reverse" hybrid robotic-laparoscopic approach. AB - METHODS: This is a prospective consecutive cohort observational study of patients who underwent robotic rectal cancer resection from January 2009 to March 2011. During the study period, a technique of reverse-hybrid robotic-laparoscopic rectal resection with radical lymphadenectomy was developed. This technique involves reversal of the operative sequence with lymphovascular and rectal dissection to precede proximal colonic mobilization. This technique evolved from a conventional-hybrid resection with laparoscopic vascular control, colonic mobilization, and robotic pelvic dissection. Perioperative and short-term oncologic outcomes were analyzed. AB - RESULTS: Thirty patients underwent reverse-hybrid resection. Median tumor location was 5 cm (interquartile range 3-9) from the anal verge. Median BMI was 27.6 (interquartile range 25.0-32.1 kg/m). Twenty (66.7%) received neoadjuvant chemoradiation. There were no conversions. Median blood loss was 100 mL (interquartile range 75-200). Total operation time was a median 369 (interquartile range 306-410) minutes. Median docking time was 6 (interquartile range 5-8) minutes, and console time was 98 (interquartile range 88-140) minutes. Resection was R0 in all patients; no patients had an incomplete mesorectal resection. Six patients (20%) underwent extended lymph node dissection or en bloc resection. AB - CONCLUSIONS: Reverse-hybrid robotic surgery for rectal cancer maximizes the therapeutic applicability of the robotic and conventional laparoscopic techniques for optimized application in minimally invasive rectal surgery. ES - 1530-0358 IL - 0012-3706 DI - 00003453-201202000-00019 DO - https://dx.doi.org/10.1097/DCR.0b013e31823c0bd2 PT - Clinical Trial PT - Journal Article PT - Research Support, N.I.H., Extramural ID - 22228169 [pubmed] ID - 10.1097/DCR.0b013e31823c0bd2 [doi] ID - 00003453-201202000-00019 [pii] ID - PMC3546550 [pmc] ID - NIHMS374946 [mid] PP - ppublish GI - No: K07 CA133187 Organization: (CA) *NCI NIH HHS* Country: United States No: K07-CA133187 Organization: (CA) *NCI NIH HHS* Country: United States LG - English DP - 2012 Feb DC - 20120109 EZ - 2012/01/10 06:00 DA - 2012/03/08 06:00 DT - 2012/01/10 06:00 YR - 2012 ED - 20120307 RD - 20161019 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22228169 <364. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22177178 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lucas SM AU - Sundaram CP AU - Wolf JS Jr AU - Leveillee RJ AU - Bird VG AU - Aziz M AU - Pautler SE AU - Luke P AU - Erdeljan P AU - Baldwin DD AU - Ebrahimi K AU - Nadler RB AU - Rebuck D AU - Thomas R AU - Lee BR AU - Boylu U AU - Figenshau RS AU - Munver R AU - Averch TD AU - Gayed B AU - Shalhav AL AU - Gundeti MS AU - Castle EP AU - Anderson JK AU - Duffey BG AU - Landman J AU - Okhunov Z AU - Wong C AU - Strom KH FA - Lucas, Steven M FA - Sundaram, Chandru P FA - Wolf, J Stuart Jr FA - Leveillee, Raymond J FA - Bird, Vincent G FA - Aziz, Mohamed FA - Pautler, Stephen E FA - Luke, Patrick FA - Erdeljan, Peter FA - Baldwin, D Duane FA - Ebrahimi, Kamyar FA - Nadler, Robert B FA - Rebuck, David FA - Thomas, Raju FA - Lee, Benjamin R FA - Boylu, Ugur FA - Figenshau, Robert S FA - Munver, Ravi FA - Averch, Timothy D FA - Gayed, Bishoy FA - Shalhav, Arieh L FA - Gundeti, Mohan S FA - Castle, Erik P FA - Anderson, J Kyle FA - Duffey, Branden G FA - Landman, Jaime FA - Okhunov, Zhamshid FA - Wong, Carson FA - Strom, Kurt H IN - Lucas, Steven M. Indiana University, Indianapolis, IN, USA. TI - Factors that impact the outcome of minimally invasive pyeloplasty: results of the Multi-institutional Laparoscopic and Robotic Pyeloplasty Collaborative Group. SO - Journal of Urology. 187(2):522-7, 2012 Feb AS - J Urol. 187(2):522-7, 2012 Feb NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Female MH - Humans MH - *Kidney Pelvis/su [Surgery] MH - *Laparoscopy MH - Male MH - Minimally Invasive Surgical Procedures MH - *Nephrectomy/mt [Methods] MH - Retrospective Studies MH - *Robotics MH - *Ureteral Obstruction/su [Surgery] AB - PURPOSE: We compared laparoscopic and robotic pyeloplasty to identify factors associated with procedural efficacy. AB - MATERIALS AND METHODS: We conducted a retrospective multicenter trial incorporating 865 cases from 15 centers. We collected perioperative data including anatomical and procedural factors. Failure was defined subjectively as pain that was unchanged or worse per medical records after surgery. Radiographic failure was defined as unchanged or worsening drainage on renal scans or worsening hydronephrosis on computerized tomography. Bivariate analyses were performed on all outcomes and multivariate analysis was used to assess factors associated with decreased freedom from secondary procedures. AB - RESULTS: Of the cases 759 (274 laparoscopic pyeloplasties with a mean followup of 15 months and 465 robotic pyeloplasties with a mean followup of 11 months, p <0.001) had sufficient data. Laparoscopic pyeloplasty, previous endopyelotomy and intraoperative crossing vessels were associated with decreased freedom from secondary procedures on bivariate analysis, with a 2-year freedom from secondary procedures of 87% for laparoscopic pyeloplasty vs 95% for robotic pyeloplasty, 81% vs 93% for patients with vs without previous endopyelotomy and 88% vs 95% for patients with vs without intraoperative crossing vessels, respectively. However, on multivariate analysis only previous endopyelotomy (HR 4.35) and intraoperative crossing vessels (HR 2.73) significantly impacted freedom from secondary procedures. AB - CONCLUSIONS: Laparoscopic and robotic pyeloplasty are highly effective in treating ureteropelvic junction obstruction. There was no difference in their abilities to render the patient free from secondary procedures on multivariate analysis. Previous endopyelotomy and intraoperative crossing vessels reduced freedom from secondary procedures. AB - Copyright © 2012 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(11)05239-6 DO - https://dx.doi.org/10.1016/j.juro.2011.09.158 PT - Clinical Trial PT - Journal Article PT - Multicenter Study ID - 22177178 [pubmed] ID - S0022-5347(11)05239-6 [pii] ID - 10.1016/j.juro.2011.09.158 [doi] PP - ppublish PH - 2011/06/02 [received] LG - English EP - 20111215 DP - 2012 Feb DC - 20120112 EZ - 2011/12/20 06:00 DA - 2012/03/07 06:00 DT - 2011/12/20 06:00 YR - 2012 ED - 20120306 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22177178 <365. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22177176 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hung AJ AU - Patil MB AU - Zehnder P AU - Cai J AU - Ng CK AU - Aron M AU - Gill IS AU - Desai MM FA - Hung, Andrew J FA - Patil, Mukul B FA - Zehnder, Pascal FA - Cai, Jie FA - Ng, Casey K FA - Aron, Monish FA - Gill, Inderbir S FA - Desai, Mihir M IN - Hung, Andrew J. Catherine and Joseph Aresty Department of Urology, University of Southern California Institute of Urology, Los Angeles, CA, USA. ajhung@gmail.com TI - Concurrent and predictive validation of a novel robotic surgery simulator: a prospective, randomized study. SO - Journal of Urology. 187(2):630-7, 2012 Feb AS - J Urol. 187(2):630-7, 2012 Feb NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Animals MH - *Computer Simulation MH - Humans MH - *Laparoscopy/ed [Education] MH - Laparoscopy/mt [Methods] MH - Models, Animal MH - Prospective Studies MH - *Robotics/ed [Education] MH - Single-Blind Method AB - PURPOSE: We evaluated the concurrent and predictive validity of a novel robotic surgery simulator in a prospective, randomized study. AB - MATERIALS AND METHODS: A total of 24 robotic surgery trainees performed virtual reality exercises on the da Vinci Skills Simulator using the da Vinci SiTM surgeon console. Baseline simulator performance was captured. Baseline live robotic performance on ex vivo animal tissue exercises was evaluated by 3 expert robotic surgeons using validated laparoscopic assessment metrics. Trainees were then randomized to group 1-simulator training and group 2-no training while matched for baseline tissue scores. Group 1 trainees underwent a 10-week simulator curriculum. Repeat tissue exercises were done at study conclusion to assess performance improvement. Spearman's analysis was used to correlate baseline simulator performance with baseline ex vivo tissue performance (concurrent validity) and final tissue performance (predictive validity). The Kruskal-Wallis test was used to compare group performance. AB - RESULTS: Groups 1 and 2 were comparable in pre-study surgical experience and had similar baseline scores on simulator and tissue exercises (p >0.05). Overall baseline simulator performance significantly correlated with baseline and final tissue performance (concurrent and predictive validity each r = 0.7, p <0.0001). Simulator training significantly improved tissue performance on key metrics for group 1 subjects with lower baseline tissue scores (below the 50th percentile) than their group 2 counterparts (p <0.05). Group 1 tended to outperform group 2 on final tissue performance, although the difference was not significant (p >0.05). AB - CONCLUSIONS: Our study documents the concurrent and predictive validity of the Skills Simulator. The benefit of simulator training appears to be most substantial for trainees with low baseline robotic skills. AB - Copyright © 2012 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(11)05235-9 DO - https://dx.doi.org/10.1016/j.juro.2011.09.154 PT - Journal Article PT - Randomized Controlled Trial PT - Validation Studies ID - 22177176 [pubmed] ID - S0022-5347(11)05235-9 [pii] ID - 10.1016/j.juro.2011.09.154 [doi] PP - ppublish PH - 2011/05/26 [received] LG - English EP - 20111215 DP - 2012 Feb DC - 20120112 EZ - 2011/12/20 06:00 DA - 2012/03/07 06:00 DT - 2011/12/20 06:00 YR - 2012 ED - 20120306 RD - 20120112 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22177176 <366. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22001096 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Korets R AU - Mues AC AU - Graversen JA AU - Gupta M AU - Benson MC AU - Cooper KL AU - Landman J AU - Badani KK FA - Korets, Ruslan FA - Mues, Adam C FA - Graversen, Joseph A FA - Gupta, Mantu FA - Benson, Mitchell C FA - Cooper, Kimberly L FA - Landman, Jaime FA - Badani, Ketan K IN - Korets, Ruslan. Department of Urology, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA. TI - Validating the use of the Mimic dV-trainer for robotic surgery skill acquisition among urology residents. CM - Comment in: Urology. 2011 Dec;78(6):1331; PMID: 22137698 SO - Urology. 78(6):1326-30, 2011 Dec AS - Urology. 78(6):1326-30, 2011 Dec NJ - Urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Clinical Competence MH - Humans MH - *Internship and Residency/mt [Methods] MH - *Laparoscopy/ed [Education] MH - Learning Curve MH - *Robotics/ed [Education] MH - Time Factors MH - *Urology/ed [Education] AB - OBJECTIVE: To compare robotic surgery skill acquisition of residents trained with Mimic dVTrainer (MdVT) and da Vinci Surgical System (dVSS) console. No standardized curriculum currently exists for robotic surgical education. The MdVT is a compact hardware platform that closely reproduces the experience of the dVSS. AB - METHODS: Sixteen urology trainees were randomized into 3 groups. A baseline evaluation using dVSS was performed and consisted of 2 exercises requiring endowrist manipulation (EM), camera movement and clutching (CC), needle control (NC), and knot-tying (KT). Groups 1 and 2 completed a standardized training curriculum on MdVT and dVSS, respectively. Group 3 received no additional training. After completion of the training phase, all trainees completed a secondary evaluation on dVSS consisting of the same exercises performed during baseline evaluation. AB - RESULTS: There was no difference in baseline performance scores across the 3 groups. Although Group 3 showed no significant improvement in EM/CC domain (P = .15), Groups 1 and 2 had statistically significant improvement in EM/CC domain (P = .039 and P = .007, respectively). The difference in improvement between Groups 1 and group 2 was not statistically different (P = .21). Only Group 2 trainees showed significant improvement in the NC and KT domains during secondary evaluation (P = .02). AB - CONCLUSION: Curriculum-based training with MdVT or dVSS significantly improves robotic surgery aptitude. Similar improvements are seen for exercise domains shared between MdVT and dVSS groups. Follow-up studies are necessary to assess the efficacy of MdVT over a wider spectrum of domains. AB - Copyright © 2011 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(11)02295-3 DO - https://dx.doi.org/10.1016/j.urology.2011.07.1426 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 22001096 [pubmed] ID - S0090-4295(11)02295-3 [pii] ID - 10.1016/j.urology.2011.07.1426 [doi] PP - ppublish PH - 2011/03/31 [received] PH - 2011/06/25 [revised] PH - 2011/07/09 [accepted] LG - English EP - 20111015 DP - 2011 Dec DC - 20111205 EZ - 2011/10/18 06:00 DA - 2012/02/09 06:00 DT - 2011/10/18 06:00 YR - 2011 ED - 20120208 RD - 20120406 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22001096 <367. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21443972 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Comploj E AU - Palermo S AU - Trenti E AU - Martini T AU - Lodde M AU - Mian C AU - Mazzoleni G AU - Pycha A FA - Comploj, Evi FA - Palermo, Salvatore FA - Trenti, Emanuela FA - Martini, Thomas FA - Lodde, Michele FA - Mian, Christine FA - Mazzoleni, Guido FA - Pycha, Armin IN - Comploj, Evi. Department of Urology, Central Hospital of Bolzano, Lorenz Bohler Street 5, 39100 Bolzano, Italy. complojevi94@yahoo.de TI - Radical perineal prostatectomy: An outdated procedure?. SO - International Journal Of Surgery. 9(5):400-3, 2011 AS - Int J Surg. 9(5):400-3, 2011 NJ - International journal of surgery (London, England) PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101228232 IO - Int J Surg SB - Index Medicus CP - England MH - Aged MH - Erectile Dysfunction/ep [Epidemiology] MH - Erectile Dysfunction/et [Etiology] MH - Humans MH - Intraoperative Complications/ep [Epidemiology] MH - Male MH - Middle Aged MH - Minimally Invasive Surgical Procedures MH - Perineum MH - *Postoperative Complications/ep [Epidemiology] MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/mo [Mortality] MH - *Prostatic Neoplasms/su [Surgery] MH - Quality of Life MH - Survival Analysis MH - Treatment Outcome MH - Urinary Incontinence/ep [Epidemiology] MH - Urinary Incontinence/et [Etiology] AB - OBJECTIVES: Radical perineal prostatectomy (RPP) is an alternative to the retropubic, laparoscopic or robotic prostatectomy approaches. This study reports the experience with RPP of a single surgeon at a single institution; the technical aspects, oncological outcome, and complications, such as urinary incontinence and erectile dysfunction, were investigated. AB - METHODS: A total of 212 consecutive patients with a mean age of 63 (range 45-74) years and clinically localised prostate cancer were monitored. Between January 2001 and December 2010, all patients underwent RPP that was performed by a single experienced surgeon at one institution. All data were introduced into a database focussing on the intra-operative and post-operative complications, continence rate, potency and oncological outcome. AB - RESULTS: The mean follow-up was 48 (6-117) months. Intra-operative complications, both early and late, occurred in 19% of the patients. The average length of in-hospital stay was 9 (3-45) days, and the mean period of time spent with a urethral catheter in place was 9 (4-45) days. The continence rate was 81%, and the potency rate, without any pharmacological aid, was 27%. The overall PSA-free survival rate was 86%. There was one cancer-specific death. AB - CONCLUSION: On the basis of our prospective data, we conclude that RPP provides satisfactory oncological results with an acceptable outcome in terms of quality of life. RPP can be considered to be mini-invasive and achieves results that are equivalent to those of the alternative surgical approaches. AB - Copyright © 2011 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved. ES - 1743-9159 IL - 1743-9159 DI - S1743-9191(11)00065-3 DO - https://dx.doi.org/10.1016/j.ijsu.2011.03.027 PT - Clinical Trial PT - Journal Article ID - 21443972 [pubmed] ID - S1743-9191(11)00065-3 [pii] ID - 10.1016/j.ijsu.2011.03.027 [doi] PP - ppublish PH - 2010/12/19 [received] PH - 2011/03/06 [revised] PH - 2011/03/12 [accepted] LG - English EP - 20110402 DP - 2011 DC - 20110627 EZ - 2011/03/30 06:00 DA - 2012/02/03 06:00 DT - 2011/03/30 06:00 YR - 2011 ED - 20120202 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21443972 <368. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21996262 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Rossi EC AU - Ivanova A AU - Boggess JF FA - Rossi, Emma C FA - Ivanova, Anastasia FA - Boggess, John F IN - Rossi, Emma C. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, USA. ecrossi@iupui.edu TI - Robotically assisted fluorescence-guided lymph node mapping with ICG for gynecologic malignancies: a feasibility study. CM - Comment in: Gynecol Oncol. 2012 Jun;125(3):764; author reply 765; PMID: 22333996 SO - Gynecologic Oncology. 124(1):78-82, 2012 Jan AS - Gynecol Oncol. 124(1):78-82, 2012 Jan NJ - Gynecologic oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - fxc, 0365304 IO - Gynecol. Oncol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - *Coloring Agents MH - Endometrial Neoplasms/di [Diagnosis] MH - *Endometrial Neoplasms/pa [Pathology] MH - Feasibility Studies MH - Female MH - Humans MH - *Indocyanine Green MH - *Lymph Nodes/pa [Pathology] MH - Lymphatic Metastasis MH - Middle Aged MH - Prospective Studies MH - Robotics/mt [Methods] MH - *Sentinel Lymph Node Biopsy/mt [Methods] MH - *Spectroscopy, Near-Infrared/mt [Methods] MH - Uterine Cervical Neoplasms/di [Diagnosis] MH - *Uterine Cervical Neoplasms/pa [Pathology] AB - OBJECTIVE: Traditional techniques of sentinel lymph node (SLN) mapping for endometrial and cervical cancer present challenges which may be overcome with newer technologies such as near infrared (NIR) imaging of the fluorescent dye Indocyanine green (ICG). We performed a feasibility and dose-finding study to define the dose of ICG required to identify pelvic and para-aortic sentinel lymph nodes with robotically assisted endoscopic NIR imaging after cervical injection. AB - METHODS: 20 subjects with cervical or endometrial carcinoma were prospectively enrolled for SLN mapping. ICG was injected into the cervical stroma at 3 o'clock and 9 o'clock Data was collected for the number of nodes identified, the location of SLN's, the duration of procedure and the pathology characteristics of the SLN's compared to the non-sentinel lymph nodes. AB - RESULTS: 20 subjects received cervical injection with at least one SLN observed in 17 subjects. 15 of the 17 subjects who received 1mg injections of ICG mapped a SLN for an observed detection rate of 88% (95% CI is (64%,99%)). A median of 4.5 SLN's was identified per patient. Three patients had lymphatic metastases, one of whom had a positive SLN. No adverse events were identified. AB - CONCLUSIONS: A 1mg cervical injection of ICG identified a SLN in 88% of patients (95% CI is (64%, 99%)). Robotically assisted fluorescence imaging is a feasible, safe, time efficient and reliable method for lymphatic mapping in early stage cervical and endometrial cancer. AB - Copyright © 2011 Elsevier Inc. All rights reserved. RN - 0 (Coloring Agents) RN - IX6J1063HV (Indocyanine Green) ES - 1095-6859 IL - 0090-8258 DI - S0090-8258(11)00795-5 DO - https://dx.doi.org/10.1016/j.ygyno.2011.09.025 PT - Clinical Trial PT - Journal Article ID - 21996262 [pubmed] ID - S0090-8258(11)00795-5 [pii] ID - 10.1016/j.ygyno.2011.09.025 [doi] PP - ppublish PH - 2011/08/11 [received] PH - 2011/09/09 [revised] PH - 2011/09/17 [accepted] LG - English EP - 20111011 DP - 2012 Jan DC - 20111214 EZ - 2011/10/15 06:00 DA - 2012/01/31 06:00 DT - 2011/10/15 06:00 YR - 2012 ED - 20120130 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21996262 <369. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21834656 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Richards KA AU - Kader K AU - Pettus JA AU - Smith JJ AU - Hemal AK FA - Richards, Kyle A FA - Kader, Karim FA - Pettus, Joseph A FA - Smith, John J FA - Hemal, Ashok K IN - Richards, Kyle A. Department of Urology, Wake Forest University, Winston-Salem, North Carolina 27157, USA. TI - Does initial learning curve compromise outcomes for robot-assisted radical cystectomy? A critical evaluation of the first 60 cases while establishing a robotics program. SO - Journal of Endourology. 25(9):1553-8, 2011 Sep AS - J Endourol. 25(9):1553-8, 2011 Sep NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Aged MH - Aged, 80 and over MH - Cystectomy/ae [Adverse Effects] MH - *Cystectomy/ed [Education] MH - *Cystectomy/mt [Methods] MH - Female MH - Humans MH - *Learning Curve MH - Male MH - Middle Aged MH - Postoperative Complications/et [Etiology] MH - *Program Evaluation MH - *Robotics/ed [Education] MH - Treatment Outcome AB - BACKGROUND AND PURPOSE: Robot-assisted laparoscopic radical cystectomy (RARC) with pelvic lymph node dissection (PLND) has gained popularity as a minimally invasive alternative to open radical cystectomy (ORC) for the treatment of patients with bladder cancer. The learning curve (LC) for laparoscopic and robotic surgery can be steep. We aim to evaluate the effect of the initial LC on operative, postoperative, and pathologic outcomes of the first 60 RARC performed at our newly established robotics program. AB - PATIENTS AND METHODS: After obtaining Institutional Review Board approval, we reviewed the clinical and pathologic data from 60 consecutive patients with clinically localized bladder cancer who underwent RARC with PLND from January 2008 to March 2010. The patients were grouped into tertiles and assessed for effect of LC using analysis of variance. AB - RESULTS: Patient demographics and clinical characteristics were similar across tertiles. The mean total operative time trended down from the 1st to 3rd tertile from 525 minutes to 449 minutes, respectively (P=0.059). Mean estimated blood loss was unchanged across tertiles. Complications decreased as the LC progressed from 14 (70%) in the 1st tertile to 6 (30%) in each of the 2nd and 3rd tertiles (P<0.013). The mean total lymph node yield and number of positive margins were unchanged across tertiles. AB - CONCLUSIONS: RARC with PLND can be performed safely at a high-volume newly established robotic surgery program with an experienced team without compromising operative, postoperative, and short-term pathologic outcomes during the LC for surgeons who are experienced in ORC. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2010.0630 PT - Clinical Trial PT - Journal Article ID - 21834656 [pubmed] ID - 10.1089/end.2010.0630 [doi] PP - ppublish LG - English EP - 20110811 DP - 2011 Sep DC - 20110909 EZ - 2011/08/13 06:00 DA - 2012/01/19 06:00 DT - 2011/08/13 06:00 YR - 2011 ED - 20120118 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21834656 <370. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21823984 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Polland AR AU - Graversen JA AU - Mues AC AU - Badani KK FA - Polland, Allison R FA - Graversen, Joseph A FA - Mues, Adam C FA - Badani, Ketan K IN - Polland, Allison R. Department of Urology, Columbia University Medical Center, New York, New York 10032, USA. TI - Polyglyconate unidirectional barbed suture for posterior reconstruction and anastomosis during robot-assisted prostatectomy: effect on procedure time, efficacy, and minimum 6-month follow-up. SO - Journal of Endourology. 25(9):1493-6, 2011 Sep AS - J Endourol. 25(9):1493-6, 2011 Sep NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Anastomosis, Surgical MH - Follow-Up Studies MH - Humans MH - Male MH - *Polymers/ch [Chemistry] MH - Prostate/pa [Pathology] MH - *Prostate/su [Surgery] MH - *Prostatectomy/mt [Methods] MH - *Reconstructive Surgical Procedures/mt [Methods] MH - *Robotics MH - *Sutures MH - Time Factors MH - Treatment Outcome MH - Wound Healing AB - BACKGROUND AND PURPOSE: With widespread implementation of posterior rhabdosphincter reconstruction (RSR) followed by urethrovesical anastomosis (UVA), reconstruction has become a significant portion of robot-assisted laparoscopic prostatectomy (RALP). Successful anastomosis can be measured by time for reconstruction and the absence of urinary leak. We prospectively evaluated the experience of a single surgeon (KKB) in using the V-LocTM wound closure device for the posterior RSR and UVA, and compared it with a standard reconstruction and anastomosis. AB - PATIENTS AND METHODS: A total of 84 patients divided into two groups underwent RALP, undergoing RSR and UVA using a Van Velthoven technique with the V-Loc or with a standard 3-0 monofilament suture. The primary end point was the time to complete RSR, UVA, and the total reconstruction. As a secondary end point, the clinical evidence of an anastomotic leak was also documented. AB - RESULTS: The mean RSR, UVA, and total times were 9, 18, and 27 minutes for the control group, and 6, 12 and 18 minutes for the V-Loc group, respectively. The time differences between the two groups for RSR, UVA, and total time were 3 minutes (P<0.01), 6 minutes (P<0.01), and 9 minutes (P<0.001), respectively. There was no clinical evidence of anastomotic leak in either group. Continence recovery was equivalent between the groups at 6 weeks and 6 months. At a 9-month follow-up, no patients in either group had a clinical UVA stricture necessitating intervention. AB - CONCLUSIONS: The V-Loc suture is associated with a significantly shorter time for the RSR and UVA compared with the traditional suture and is not associated with a higher incidence of clinical urinary leak; however, a larger randomized study with long-term follow-up is necessary to confirm these results. RN - 0 (Polymers) RN - 75734-93-9 (polyglyconate) ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2010.0668 PT - Clinical Trial PT - Journal Article ID - 21823984 [pubmed] ID - 10.1089/end.2010.0668 [doi] PP - ppublish LG - English EP - 20110808 DP - 2011 Sep DC - 20110909 EZ - 2011/08/10 06:00 DA - 2012/01/19 06:00 DT - 2011/08/10 06:00 YR - 2011 ED - 20120118 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21823984 <371. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21484533 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Leong QM AU - Son DN AU - Cho JS AU - Baek SJ AU - Kwak JM AU - Amar AH AU - Kim SH FA - Leong, Quor M FA - Son, Dong N FA - Cho, Jae S FA - Baek, Se J FA - Kwak, Jung M FA - Amar, Azali H FA - Kim, Seon H IN - Leong, Quor M. Korea University College of Medicine, Korea University Anam Hospital, 126-1 Anam-dong 5-ga, SungBook-gu, Seoul 136-705, Korea. quormeng@gmail.com TI - Robot-assisted intersphincteric resection for low rectal cancer: technique and short-term outcome for 29 consecutive patients. SO - Surgical Endoscopy. 25(9):2987-92, 2011 Sep AS - Surg Endosc. 25(9):2987-92, 2011 Sep NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adenocarcinoma/dt [Drug Therapy] MH - Adenocarcinoma/rt [Radiotherapy] MH - *Adenocarcinoma/su [Surgery] MH - Adult MH - Aged MH - Aged, 80 and over MH - *Anal Canal/su [Surgery] MH - Anus Neoplasms/dt [Drug Therapy] MH - Anus Neoplasms/rt [Radiotherapy] MH - *Anus Neoplasms/su [Surgery] MH - Combined Modality Therapy MH - Feasibility Studies MH - Female MH - Humans MH - *Laparoscopy/mt [Methods] MH - Length of Stay/sn [Statistics & Numerical Data] MH - Lymph Node Excision/mt [Methods] MH - Male MH - Middle Aged MH - Neoadjuvant Therapy MH - Postoperative Complications/ep [Epidemiology] MH - Prospective Studies MH - Rectal Neoplasms/dt [Drug Therapy] MH - Rectal Neoplasms/rt [Radiotherapy] MH - *Rectal Neoplasms/su [Surgery] MH - *Robotics MH - Treatment Outcome AB - BACKGROUND: Intersphincteric resection (ISR) for low rectal cancer has been described as the ultimate sphincter-saving procedure. Laparoscopic ISR has been proved safe with early postoperative benefits. Recently, some colorectal surgeons have begun to perform robot-assisted ISR to harness the advantages of the da Vinci robotic system. The authors present their short-term results for a robotic technique of ISR. AB - METHODS: Data from 29 consecutive patients at a single institution with very low rectal cancer (<4 cm) from the anal verge who underwent robot-assisted ISR were prospectively collected between December 2007 and March 2010. AB - RESULTS: The study enrolled 23 men and 6 women with a median age of 61.5 years (range, 36-82 years). Their median body mass index (BMI) was 23.3 kg/m(2) (range, 17.9-32.5 kg/m(2)). The median distance of the tumor from the anal verge was 3 cm (range, 1-4 cm). The median operative time was 325 min (range, 235-435 min), with a console time of 130 min (range, 110-210 min). There were no conversions to open surgery. A protecting ileostomy was performed for all the patients. The median blood loss was less than 50 ml (range, < 50-1,000 ml). The median size of the tumor was 3 cm (range, 0-6.9 cm), and the median number of lymph nodes harvested was 16 (range, 1-44). The median distal margin was 0.8 cm (range, 0-4 cm), and one margin was positive. The circumferential margin was negative (>2 mm) for 27 patients. Therefore, complete resection (R0) was achieved for 26 (90%) of the 29 patients. The median hospital stay was 9 days (range, 5-15 days). Nine patients experienced complications, including three anastomotic leaks (10%). All the leaks were managed conservatively. No surgical mortalities occurred. AB - CONCLUSION: Robot-assisted intersphincteric resection for very low rectal cancer is feasible, and its short-term outcome is acceptable. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-011-1657-6 PT - Clinical Trial PT - Journal Article ID - 21484533 [pubmed] ID - 10.1007/s00464-011-1657-6 [doi] PP - ppublish PH - 2010/11/23 [received] PH - 2011/02/20 [accepted] LG - English EP - 20110412 DP - 2011 Sep DC - 20110824 EZ - 2011/04/13 06:00 DA - 2012/01/06 06:00 DT - 2011/04/13 06:00 YR - 2011 ED - 20120105 RD - 20110824 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21484533 <372. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21690436 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Wren SM AU - Curet MJ FA - Wren, Sherry M FA - Curet, Myriam J IN - Wren, Sherry M. Department of Surgery, Stanford University School of Medicine, Stanford, USA. swren@stanford.edu TI - Single-port robotic cholecystectomy: results from a first human use clinical study of the new da Vinci single-site surgical platform. CM - Comment in: Arch Surg. 2011 Oct;146(10):1127; PMID: 22121529 SO - Archives of Surgery. 146(10):1122-7, 2011 Oct AS - Arch Surg. 146(10):1122-7, 2011 Oct NJ - Archives of surgery (Chicago, Ill. : 1960) PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 8ia, 9716528 IO - Arch Surg SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - *Cholecystectomy, Laparoscopic/is [Instrumentation] MH - Equipment Design MH - Feasibility Studies MH - Female MH - *Gallbladder Diseases/su [Surgery] MH - Hospitals, Veterans MH - Humans MH - Male MH - Middle Aged MH - Patient Satisfaction MH - Retrospective Studies MH - *Robotics/is [Instrumentation] MH - Treatment Outcome AB - OBJECTIVES: To report our results from a first human use clinical study with the da Vinci Surgical single-site instrumentation in patients with gallbladder disease and to perform a retrospective comparison with traditional multiport laparoscopic cholecystectomy. AB - DESIGN: Ten patients underwent robotic single-port cholecystectomy performed with the da Vinci Si robot and novel da Vinci single-site instrumentation. Outcomes and operative times were compared with patients undergoing traditional multiport laparoscopic cholecystectomy during the same period. AB - SETTING: Tertiary care Veterans Administration hospital. AB - PATIENTS: Outpatients older than 18 years with an American Society of Anesthesiologists class of 1 to 3, no prior upper abdominal surgery, and diagnosis of noninflammatory biliary disease. AB - INTERVENTION: Single-site robotic cholecystectomy. AB - MAIN OUTCOME MEASURES: Operative time, complications up to 30 days, pain scores, and overall satisfaction. AB - RESULTS: Nine of 10 patients had completion of robotic single-site cholecystectomy. Average operating room time was 105.3 minutes compared with an average of 106.1 minutes in the standard laparoscopic group. There were no serious adverse events in the robotic surgery group, with an average follow-up of 3 or more months. AB - CONCLUSION: Robotic single-port cholecystectomy is feasible and comparable with standard laparoscopic cholecystectomy in the Veterans Administration medical center setting. ES - 1538-3644 IL - 0004-0010 DI - archsurg.2011.143 DO - https://dx.doi.org/10.1001/archsurg.2011.143 PT - Controlled Clinical Trial PT - Journal Article ID - 21690436 [pubmed] ID - archsurg.2011.143 [pii] ID - 10.1001/archsurg.2011.143 [doi] PP - ppublish LG - English EP - 20110620 DP - 2011 Oct DC - 20111018 EZ - 2011/06/22 06:00 DA - 2011/12/30 06:00 DT - 2011/06/22 06:00 YR - 2011 ED - 20111229 RD - 20111018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21690436 <373. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21940041 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ho H AU - Yuen JS AU - Mohan P AU - Lim EW AU - Cheng CW FA - Ho, H FA - Yuen, J S P FA - Mohan, P FA - Lim, E W FA - Cheng, C W S IN - Ho, H. Department of Urology, Singapore General Hospital, Singapore. ho.henry.s.s@gmail.com TI - Robotic transperineal prostate biopsy: pilot clinical study. SO - Urology. 78(5):1203-8, 2011 Nov AS - Urology. 78(5):1203-8, 2011 Nov NJ - Urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Aged MH - Biopsy, Needle/is [Instrumentation] MH - *Biopsy, Needle/mt [Methods] MH - Equipment Design MH - Humans MH - Male MH - Middle Aged MH - Perineum MH - Pilot Projects MH - Prospective Studies MH - *Prostate/pa [Pathology] MH - Robotics/is [Instrumentation] MH - *Robotics AB - OBJECTIVE: To develope a robot (BioXbot) that performs mapping transperineal prostate biopsy (PB) with two perineal skin punctures under ultrasound guidance. Our pilot study's clinical endpoints were complications and its technical endpoints were the duration for each phase. AB - METHODS: This institution review board-approved prospective clinical trial included patients with indications for PB. Two urologists performed these PBs. In the lithotomy position and under general anesthesia, the transrectal biplane ultrasound probe acquired transverse images of the prostate gland. The urologist defined its boundaries and planned the biopsy. It guided the PB in 3 axes, passing through a single perineal skin puncture for each prostate side. After each biopsy, it automatically moved to the next position. The steps were repeated on the contralateral side. AB - RESULTS: Our 20 patients had a mean prostate-specific antigen of 8.4 +/- 4.9 ng/mL. Two patients had 2 previous biopsies, whereas the rest had one. The mean number of biopsies taken was 28.5 +/- 6.2 in a mean total procedure time of 32.5 +/- 3.2 minutes. We detected 3 patients with prostate cancer with Gleason score 3 + 3. Two patients required brief bladder catheterization after their biopsy. Their prostate volumes were >50 mL and the number of biopsies taken was >30 cores. There was no mechanical failure, sepsis, bleeding per-rectal, or perineal hematoma. AB - CONCLUSION: This pilot study demonstrated BioXbot's safety and feasibility as a biopsy platform. It can potentially be used for image-guided PB and focal therapy. AB - Copyright A© 2011 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(11)02130-3 DO - https://dx.doi.org/10.1016/j.urology.2011.07.1389 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 21940041 [pubmed] ID - S0090-4295(11)02130-3 [pii] ID - 10.1016/j.urology.2011.07.1389 [doi] PP - ppublish PH - 2011/03/29 [received] PH - 2011/06/08 [revised] PH - 2011/07/09 [accepted] LG - English EP - 20110921 DP - 2011 Nov DC - 20111107 EZ - 2011/09/24 06:00 DA - 2011/12/28 06:00 DT - 2011/09/24 06:00 YR - 2011 ED - 20111227 RD - 20111107 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21940041 <374. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21470359 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Feifer A AU - Al-Ammari A AU - Kovac E AU - Delisle J AU - Carrier S AU - Anidjar M FA - Feifer, Andrew FA - Al-Ammari, Adel FA - Kovac, Evan FA - Delisle, Josee FA - Carrier, Serge FA - Anidjar, Maurice IN - Feifer, Andrew. McGill University Health Center, Division of Urology, Department of Surgery, Montreal, Canada. feifera@mskcc.org TI - Randomized controlled trial of virtual reality and hybrid simulation for robotic surgical training. SO - BJU International. 108(10):1652-6; discussion 1657, 2011 Nov AS - BJU Int. 108(10):1652-6; discussion 1657, 2011 Nov NJ - BJU international PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - dcu, 100886721 IO - BJU Int. SB - Index Medicus CP - England MH - *Clinical Competence/st [Standards] MH - *Computer Simulation MH - *Education, Medical/mt [Methods] MH - Humans MH - *Laparoscopy/ed [Education] MH - *Robotics/ed [Education] MH - Teaching/mt [Methods] MH - User-Computer Interface AB - OBJECTIVE: To evaluate if two commonly used laparoscopic simulators could be adapted and used successfully for the robotics platform in a laparoscopic and robotic naive medical student population. AB - MATERIALS AND METHODS: We identified two widely validated laparoscopic simulation programs, LapSim() (Surgical Science Sweden AB), and ProMIS() (Haptica, Ireland)for inclusion in the study. The McGill Inanimate System for Training and Evaluation of Laparoscopic Skills() task set was used for ProMIS, and adapted for the DaVinci() console (Intuitive Surgical, Inc., Sunnyvale, CA, USA) robotic platform. We then randomized 20 naive medical students to receive training on either LapSim or ProMIS, both or neither, and evaluated them before and after training. AB - RESULTS: When the groups were compared at baseline, there were no statistical differences in mean scores amongst the groups in univariate analysis (alpha= 0.05). When comparing mean scores within groups before and after training sessions, statistically significant performance enhancement in all four robotic tasks were identified in the groups receiving dual training. AB - CONCLUSION: We have shown that the use of ProMIS hybrid and LapSim virtual reality (VR) simulators in conjunction with each other can considerable improve robotic console performance in novice medical students compared with hybrid and VR simulation alone. AB - Copyright © 2011 BJU INTERNATIONAL. NO CLAIM TO ORIGINAL US GOVERNMENT WORKS. ES - 1464-410X IL - 1464-4096 DO - https://dx.doi.org/10.1111/j.1464-410X.2010.10060.x PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 21470359 [pubmed] ID - 10.1111/j.1464-410X.2010.10060.x [doi] PP - ppublish LG - English EP - 20110406 DP - 2011 Nov DC - 20111028 EZ - 2011/04/08 06:00 DA - 2011/12/28 06:00 DT - 2011/04/08 06:00 YR - 2011 ED - 20111227 RD - 20111028 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21470359 <375. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21410633 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Shah K AU - Abaza R FA - Shah, Ketul FA - Abaza, Ronney IN - Shah, Ketul. Department of Urology, The Ohio State University Medical Center, Columbus, 43210, USA. ketul.shah@osumc.edu TI - Comparison of intraoperative outcomes using the new and old generation da Vinci robot for robot-assisted laparoscopic prostatectomy. SO - BJU International. 108(10):1642-5, 2011 Nov AS - BJU Int. 108(10):1642-5, 2011 Nov NJ - BJU international PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - dcu, 100886721 IO - BJU Int. SB - Index Medicus CP - England MH - Blood Loss, Surgical MH - Body Mass Index MH - Humans MH - *Laparoscopy/is [Instrumentation] MH - Length of Stay MH - Lymph Node Excision MH - Male MH - Prospective Studies MH - *Prostatectomy/is [Instrumentation] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotics/is [Instrumentation] MH - Treatment Outcome MH - Urinary Bladder Neck Obstruction/su [Surgery] AB - OBJECTIVE: To review and compare intraoperative outcomes for robotic prostatectomy procedures performed on two generations of the da Vinci robotic surgery platform. AB - MATERIAL AND METHODS: We reviewed 100 consecutive robotic prostatectomy cases and compared intraoperative outcomes for procedures randomly performed on either the da Vinci S robot or first-generation standard robot. Baseline demographic data and intra-operative variables potentially impacting outcomes were reviewed and compared between the two groups. AB - RESULTS: Mean total operative time was 191 min using the standard da Vinci robot (range 132-266) versus 169 min with S robot (range 98-230), representing a mean difference of 22 min (P = 0.002). This difference was statistically significant despite no difference in mean patient BMI of 30.6 (range 19-51) for standard versus 29.3 (range 21-37) for S (P = 0.31), no difference in mean prostate size of 54.6 g (range 26-101) for standard versus 57.3 g (range 32-151) for S (P = 0.55), and no difference in frequency of nerve-sparing (P = 0.99). There was also no difference in the portions of procedures performed by residents, which in some cases was none and some the entire procedure, but the standard was more often used for the surgeon's first case of the day (P = 0.006). There was no difference in blood loss (P = 0.08), positive margins (P = 0.87), or mean number of lymph nodes removed (10.7 vs 10.6). AB - CONCLUSIONS: Both generations of da Vinci robotic technology are equally effective for PALP, but the S robot appears to allow shorter procedure times. Further such evaluations are necessary to guide institutions and public policy decision-makers on investments in newer generations of robotic technology as incremental advances continue. AB - Copyright © 2011 THE AUTHORS. BJU INTERNATIONAL © 2011 BJU INTERNATIONAL. ES - 1464-410X IL - 1464-4096 DO - https://dx.doi.org/10.1111/j.1464-410X.2011.10081.x PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 21410633 [pubmed] ID - 10.1111/j.1464-410X.2011.10081.x [doi] PP - ppublish LG - English EP - 20110316 DP - 2011 Nov DC - 20111028 EZ - 2011/03/18 06:00 DA - 2011/12/28 06:00 DT - 2011/03/18 06:00 YR - 2011 ED - 20111227 RD - 20111028 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21410633 <376. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21979458 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Paraiso MF AU - Jelovsek JE AU - Frick A AU - Chen CC AU - Barber MD FA - Paraiso, Marie Fidela R FA - Jelovsek, J Eric FA - Frick, Anna FA - Chen, Chi Chung Grace FA - Barber, Matthew D IN - Paraiso, Marie Fidela R. Cleveland Clinic, Cleveland, Ohio, USA. paraism@ccf.org TI - Laparoscopic compared with robotic sacrocolpopexy for vaginal prolapse: a randomized controlled trial. SO - Obstetrics & Gynecology. 118(5):1005-13, 2011 Nov AS - Obstet Gynecol. 118(5):1005-13, 2011 Nov NJ - Obstetrics and gynecology PI - Journal available in: Print PI - Citation processed from: Internet JC - oc2, 0401101 IO - Obstet Gynecol SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Female MH - Humans MH - Hysterectomy MH - Laparoscopy/ec [Economics] MH - *Laparoscopy/sn [Statistics & Numerical Data] MH - Middle Aged MH - Postoperative Complications/su [Surgery] MH - Robotics/ec [Economics] MH - *Robotics/sn [Statistics & Numerical Data] MH - Single-Blind Method MH - Time Factors MH - *Uterine Prolapse/su [Surgery] AB - OBJECTIVE: To compare conventional laparoscopic and robotic-assisted laparoscopic sacrocolpopexy for vaginal apex prolapse. AB - METHODS: This single-center, blinded randomized trial included participants with stage 2-4 posthysterectomy vaginal prolapse. Participants were randomized to laparoscopic or robotic sacrocolpopexy. The primary outcome was total operative time from incision to closure. Secondary outcomes were postoperative pain, functional activity, bowel and bladder symptoms, quality of life, anatomic vaginal support, and cost from a health care system perspective. AB - RESULTS: A total of 78 patients enrolled and were randomized (laparoscopic n=38; robotic n=40). Total operative time was significantly longer in the robotic group compared with the laparoscopic group (+67-minute difference; 95% confidence interval [CI] 43-89; P<.001). Anesthesia time, total time in the operating room, total sacrocolpopexy time, and total suturing time were all significantly longer in the robotic group. Participants in the robotic group also had significantly higher pain at rest and with activity during weeks 3 through 5 after surgery and required longer use of nonsteroidal anti-inflammatory drugs (median, 20 compared with 11 days, P<.005). The robotic group incurred greater cost than the laparoscopic group (mean difference +$1,936; 95% CI $417-$3,454; P=.008). Both groups demonstrated significant improvement in vaginal support and functional outcomes 1 year after surgery with no differences between groups. AB - CONCLUSION: Robotic-assisted sacrocolpopexy results in longer operating time and increased pain and cost compared with the conventional laparoscopic approach. ES - 1873-233X IL - 0029-7844 DO - https://dx.doi.org/10.1097/AOG.0b013e318231537c PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 21979458 [pubmed] ID - 10.1097/AOG.0b013e318231537c [doi] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT00551993 SL - https://clinicaltrials.gov/search/term=NCT00551993 LG - English DP - 2011 Nov DC - 20111021 EZ - 2011/10/08 06:00 DA - 2011/12/14 06:00 DT - 2011/10/08 06:00 YR - 2011 ED - 20111212 RD - 20111021 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21979458 <377. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21806915 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - PubMed-not-MEDLINE AU - Patel V FA - Patel, Vipul IN - Patel, Vipul. Global Robotics Institute, Florida Hospital-Celebration Health, Urology, 410 Celebration Place, Suite 200, Celebration, FL 34744, USA. vipul.patel.md@flhosp.org TI - Words of wisdom: Re: A prospective, non-randomized trial comparing robot-assisted laparoscopic and retropubic radical prostatectomy in one European institution. CM - Comment on: BJU Int. 2009 Aug;104(4):534-9; PMID: 19281468 SO - European Urology. 60(3):599-600, 2011 Sep AS - Eur Urol. 60(3):599-600, 2011 Sep NJ - European urology PI - Journal available in: Print PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. CP - Switzerland ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(11)00637-3 DO - https://dx.doi.org/10.1016/j.eururo.2011.06.015 PT - Comment PT - Journal Article ID - 21806915 [pubmed] ID - S0302-2838(11)00637-3 [pii] ID - 10.1016/j.eururo.2011.06.015 [doi] PP - ppublish LG - English DP - 2011 Sep DC - 20110802 EZ - 2011/08/03 06:00 DA - 2011/08/03 06:01 DT - 2011/08/03 06:00 YR - 2011 ED - 20111207 RD - 20110802 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=21806915 <378. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21487754 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Chan OC AU - Tang CN AU - Lai EC AU - Yang GP AU - Li MK FA - Chan, Oliver C Y FA - Tang, Chung Ngai FA - Lai, Eric C H FA - Yang, George P C FA - Li, Michael K W IN - Chan, Oliver C Y. Department of Surgery, Pamela Youde Nethersole Eastern Hospital, 3, Lok Man Road, Hong Kong SAR, China. olivercychan@hotmail.com TI - Robotic hepatobiliary and pancreatic surgery: a cohort study. SO - Journal of Hepato-biliary-pancreatic Sciences. 18(4):471-80, 2011 Jul AS - J Hepatobiliary Pancreat Sci. 18(4):471-80, 2011 Jul NJ - Journal of hepato-biliary-pancreatic sciences PI - Journal available in: Print PI - Citation processed from: Internet JC - 101528587 IO - J Hepatobiliary Pancreat Sci SB - Index Medicus CP - Japan MH - Adult MH - Aged MH - Aged, 80 and over MH - *Biliary Tract Diseases/su [Surgery] MH - *Cholecystectomy/mt [Methods] MH - Choledochostomy/mt [Methods] MH - Equipment Design MH - Female MH - Follow-Up Studies MH - *Hepatectomy/mt [Methods] MH - Humans MH - *Liver Diseases/su [Surgery] MH - Male MH - Middle Aged MH - *Pancreatectomy/mt [Methods] MH - *Pancreatic Diseases/su [Surgery] MH - Retrospective Studies MH - *Robotics/is [Instrumentation] MH - Treatment Outcome AB - BACKGROUND: Robotic surgery has emerged as one of the most promising surgical advances since its launch at the turn of the millennium. Despite its worldwide acceptance in many different surgical specialties, the use of robotic assistance in the field of hepatobiliary and pancreatic (HBP) surgery remains relatively unexplored. This article aims to evaluate the efficacy and outcomes of robotic HBP surgery in a single surgical center. AB - METHODS: Between May 2009 and December 2010, all patients admitted to our unit for robotic HBP surgery were evaluated. A retrospective analysis of a prospectively maintained database on clinical outcomes was performed. AB - RESULTS: There were 55 robotic HBP operations performed during the study period. There were 27 robotic liver resections (left lateral sectionectomies n = 17, left hepatectomy n = 1, other segmentectomies n = 2 and wedge resections n = 7), 12 robotic pancreatic procedures (Whipple's operations n = 8, spleen-preserving distal pancreatectomies n = 2, double bypass n = 1 and cystojejunostomy n = 1) and 16 biliary procedures (biliary enteric bypass n = 9, bile duct exploration and related procedures n = 7). The median postoperative hospital stays for robotic liver resections, biliary procedures and pancreatic operations were 5.5 days (range 3-11 days), 6 days (range 4-11 days) and 12 days (range 6-21 days), respectively. Morbidities for liver resection, biliary procedures and pancreatic operations were 7.4, 18 and 33%, respectively. There was no mortality in our series. AB - CONCLUSIONS: Robotic surgery is feasible and can be safely performed in patients with complicated HBP pathologies. Further evaluation with clinical trials is required to validate its real benefits. ES - 1868-6982 IL - 1868-6974 DO - https://dx.doi.org/10.1007/s00534-011-0389-2 PT - Comparative Study PT - Journal Article ID - 21487754 [pubmed] ID - 10.1007/s00534-011-0389-2 [doi] PP - ppublish LG - English DP - 2011 Jul DC - 20110616 EZ - 2011/04/14 06:00 DA - 2011/12/13 00:00 DT - 2011/04/14 06:00 YR - 2011 ED - 20111206 RD - 20160511 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21487754 <379. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21745117 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Davis JW AU - Achim M AU - Munsell M AU - Matin S FA - Davis, John W FA - Achim, Mary FA - Munsell, Mark FA - Matin, Surena IN - Davis, John W. Department of Urology, The University of Texas MD Anderson Cancer Center , Houston, Texas 77030, USA. johndavis@mdanderson.org TI - Effectiveness of postgraduate training for learning extraperitoneal access for robot-assisted radical prostatectomy. SO - Journal of Endourology. 25(8):1363-9, 2011 Aug AS - J Endourol. 25(8):1363-9, 2011 Aug NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180764 SB - Index Medicus CP - United States MH - Aged MH - *Education, Medical, Graduate/mt [Methods] MH - Humans MH - *Learning MH - Male MH - Middle Aged MH - *Peritoneum/su [Surgery] MH - *Program Evaluation MH - *Prostatectomy/ed [Education] MH - *Prostatectomy/mt [Methods] MH - *Robotics/ed [Education] MH - *Robotics/mt [Methods] AB - PURPOSE: To determine the effectiveness of postgraduate training for learning extraperitoneal robot-assisted radical prostatectomy (EP-RARP) and to identify any unmet training needs. AB - MATERIALS AND METHODS: The training resources used were live surgery observations, digital video disc instruction, postgraduate courses, and literature review. Modifications to the transperitoneal (TP) setup in equipment, patient positioning, port placement, and access technique were identified. A surgeon who had previous experience with 898 TP robot-assisted radical prostatectomies (TP-RARPs) performed EP-RARP in 30 patients. We evaluated setup results, emphasizing access-related difficulties, and compared the EP cohort with a nonrandomized, concurrent TP cohort of 62 patients for short-term outcomes. AB - RESULTS: The median setup time for EP was 26 minutes (range 15-65min) for EP compared with 14 to 17 minutes for the comparable TP setup and dropping the bladder. During EP setup and dissection, peritoneal entry occurred in 37%, incorrect port spacing in 10%, epigastric vessel injury in 10%, and other minor pitfalls in 10%. No significant differences were found between EP and TP in postsetup operative times, hospital stay, complications, surgical margin status with organ-confined disease, or lymph node dissection yield. EP had significantly higher estimated blood loss (300 vs 200mL, P=0.001) and more symptomatic lymphoceles when extended pelvic lymph node dissection was performed (3/16 vs 0/47, P=0.001). AB - CONCLUSIONS: Using postgraduate education resources, an experienced TP-RARP surgeon successfully transitioned to EP-RARP, achieving the major objectives of safety and equivalent outcomes. We identified several minor nuances in the setup that need further refinement in future education models. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2011.0052 PT - Clinical Trial PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't ID - 21745117 [pubmed] ID - 10.1089/end.2011.0052 [doi] ID - PMC3180764 [pmc] PP - ppublish GI - No: CA016672 Organization: (CA) *NCI NIH HHS* Country: United States LG - English EP - 20110711 DP - 2011 Aug DC - 20110805 EZ - 2011/07/13 06:00 DA - 2011/12/13 00:00 DT - 2011/07/13 06:00 YR - 2011 ED - 20111125 RD - 20161019 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21745117 <380. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22046718 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Werner JM AU - Carlson M AU - Jordan-Marsh M AU - Clark F FA - Werner, Julie M FA - Carlson, Mike FA - Jordan-Marsh, Maryalice FA - Clark, Florence IN - Werner, Julie M. University of Southern California, Los Angeles, CA 90089-2520, USA. jmwerner@usc.edu TI - Predictors of computer use in community-dwelling, ethnically diverse older adults. SO - Human Factors. 53(5):431-47, 2011 Oct AS - Hum Factors. 53(5):431-47, 2011 Oct NJ - Human factors PI - Journal available in: Print PI - Citation processed from: Print JC - ge5, 0374660 IO - Hum Factors PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3211095 OI - Source: NLM. NIHMS328323 SB - Index Medicus SB - National Aeronautics and Space Administration (NASA) Journals CP - United States MH - Adaptation, Psychological MH - Aged MH - Aged, 80 and over MH - Computers/sn [Statistics & Numerical Data] MH - *Computers/ut [Utilization] MH - *Ethnic Groups/sn [Statistics & Numerical Data] MH - Female MH - Health Status Indicators MH - Humans MH - Leisure Activities MH - Life Style MH - Logistic Models MH - Male MH - Mental Health MH - Personal Satisfaction MH - Religion MH - User-Computer Interface AB - OBJECTIVE: In this study, we analyzed self-reported computer use, demographic variables, psychosocial variables, and health and well-being variables collected from 460 ethnically diverse, community-dwelling elders to investigate the relationship computer use has with demographics, well-being, and other key psychosocial variables in older adults. AB - BACKGROUND: Although younger elders with more education, those who employ active coping strategies, or those who are low in anxiety levels are thought to use computers at higher rates than do others, previous research has produced mixed or inconclusive results regarding ethnic, gender, and psychological factors or has concentrated on computer-specific psychological factors only (e.g., computer anxiety). Few such studies have employed large sample sizes or have focused on ethnically diverse populations of community-dwelling elders. AB - METHOD: With a large number of overlapping predictors, zero-order analysis alone is poorly equipped to identify variables that are independently associated with computer use. Accordingly, both zero-order and stepwise logistic regression analyses were conducted to determine the correlates of two types of computer use: e-mail and general computer use. AB - RESULTS: Results indicate that younger age, greater level of education, non-Hispanic ethnicity, behaviorally active coping style, general physical health, and role-related emotional health each independently predicted computer usage. AB - CONCLUSION: Study findings highlight differences in computer usage, especially in regard to Hispanic ethnicity and specific health and well-being factors. AB - APPLICATION: Potential applications of this research include future intervention studies, individualized computer-based activity programming, or customizable software and user interface design for older adults responsive to a variety of personal characteristics and capabilities. IS - 0018-7208 IL - 0018-7208 DO - https://dx.doi.org/10.1177/0018720811420840 PT - Journal Article PT - Randomized Controlled Trial ID - 22046718 [pubmed] ID - PMC3211095 [pmc] ID - NIHMS328323 [mid] ID - 10.1177/0018720811420840 [doi] PP - ppublish GI - No: R01 AG021108 Organization: (AG) *NIA NIH HHS* Country: United States No: R01 AG021108-04 Organization: (AG) *NIA NIH HHS* Country: United States LG - English DP - 2011 Oct DC - 20111103 EZ - 2011/11/04 06:00 DA - 2011/12/13 00:00 DT - 2011/11/04 06:00 YR - 2011 ED - 20111122 RD - 20170214 UP - 20170215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=22046718 <381. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22046718 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Werner JM AU - Carlson M AU - Jordan-Marsh M AU - Clark F FA - Werner, Julie M FA - Carlson, Mike FA - Jordan-Marsh, Maryalice FA - Clark, Florence IN - Werner, Julie M. University of Southern California, Los Angeles, CA 90089-2520, USA. jmwerner@usc.edu TI - Predictors of computer use in community-dwelling, ethnically diverse older adults. SO - Human Factors. 53(5):431-47, 2011 Oct AS - Hum Factors. 53(5):431-47, 2011 Oct NJ - Human factors PI - Journal available in: Print PI - Citation processed from: Print JC - ge5, 0374660 IO - Hum Factors PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3211095 OI - Source: NLM. NIHMS328323 SB - Index Medicus SB - National Aeronautics and Space Administration (NASA) Journals CP - United States MH - Adaptation, Psychological MH - Aged MH - Aged, 80 and over MH - Computers/sn [Statistics & Numerical Data] MH - *Computers/ut [Utilization] MH - *Ethnic Groups/sn [Statistics & Numerical Data] MH - Female MH - Health Status Indicators MH - Humans MH - Leisure Activities MH - Life Style MH - Logistic Models MH - Male MH - Mental Health MH - Personal Satisfaction MH - Religion MH - User-Computer Interface AB - OBJECTIVE: In this study, we analyzed self-reported computer use, demographic variables, psychosocial variables, and health and well-being variables collected from 460 ethnically diverse, community-dwelling elders to investigate the relationship computer use has with demographics, well-being, and other key psychosocial variables in older adults. AB - BACKGROUND: Although younger elders with more education, those who employ active coping strategies, or those who are low in anxiety levels are thought to use computers at higher rates than do others, previous research has produced mixed or inconclusive results regarding ethnic, gender, and psychological factors or has concentrated on computer-specific psychological factors only (e.g., computer anxiety). Few such studies have employed large sample sizes or have focused on ethnically diverse populations of community-dwelling elders. AB - METHOD: With a large number of overlapping predictors, zero-order analysis alone is poorly equipped to identify variables that are independently associated with computer use. Accordingly, both zero-order and stepwise logistic regression analyses were conducted to determine the correlates of two types of computer use: e-mail and general computer use. AB - RESULTS: Results indicate that younger age, greater level of education, non-Hispanic ethnicity, behaviorally active coping style, general physical health, and role-related emotional health each independently predicted computer usage. AB - CONCLUSION: Study findings highlight differences in computer usage, especially in regard to Hispanic ethnicity and specific health and well-being factors. AB - APPLICATION: Potential applications of this research include future intervention studies, individualized computer-based activity programming, or customizable software and user interface design for older adults responsive to a variety of personal characteristics and capabilities. IS - 0018-7208 IL - 0018-7208 PT - Journal Article PT - Randomized Controlled Trial ID - 22046718 [pubmed] ID - PMC3211095 [pmc] ID - NIHMS328323 [mid] PP - ppublish GI - No: R01 AG021108 Organization: (AG) *NIA NIH HHS* Country: United States No: R01 AG021108-04 Organization: (AG) *NIA NIH HHS* Country: United States LG - English DP - 2011 Oct DC - 20111103 EZ - 2011/11/04 06:00 DA - 2011/12/13 00:00 DT - 2011/11/04 06:00 YR - 2011 ED - 20111122 RD - 20161025 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=22046718 <382. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21708364 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Diesen DL AU - Erhunmwunsee L AU - Bennett KM AU - Ben-David K AU - Yurcisin B AU - Ceppa EP AU - Omotosho PA AU - Perez A AU - Pryor A FA - Diesen, Diana L FA - Erhunmwunsee, Loretta FA - Bennett, Kyla M FA - Ben-David, Kfir FA - Yurcisin, Basil FA - Ceppa, Eugene P FA - Omotosho, Philip A FA - Perez, Alexander FA - Pryor, Aurora IN - Diesen, Diana L. Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA. dld5b@hotmail.com TI - Effectiveness of laparoscopic computer simulator versus usage of box trainer for endoscopic surgery training of novices. SO - Journal of Surgical Education. 68(4):282-9, 2011 Jul-Aug AS - J Surg Educ. 68(4):282-9, 2011 Jul-Aug NJ - Journal of surgical education PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101303204 IO - J Surg Educ SB - Index Medicus CP - United States MH - Animals MH - *Clinical Competence MH - *Computer Simulation MH - Confidence Intervals MH - Curriculum MH - Disease Models, Animal MH - *Education, Medical/mt [Methods] MH - Female MH - Humans MH - *Internship and Residency MH - *Laparoscopy/ed [Education] MH - Learning Curve MH - Male MH - *Models, Anatomic MH - Prospective Studies MH - Reference Values MH - Risk Assessment MH - Single-Blind Method MH - Students, Medical MH - Swine MH - Task Performance and Analysis MH - Time Factors MH - Young Adult AB - OBJECTIVE: Teaching of laparoscopic skills is a challenge in surgical training programs. Because of the highly technical nature and the steep learning curve, students and residents must learn laparoscopic skills before performing them in the operating room. To improve efficiency of learning and patient safety, research in simulation is essential. Two types of simulators currently in use include virtual reality and box trainers. Our study examined which simulator technique was most effective in teaching novice trainees laparoscopic techniques. AB - DESIGN: This is a prospective, randomized, blinded, controlled trial that enrolled fourth-year medical students and surgical interns to participate in a supervised 6-month laparoscopic training program with either computer simulators or box trainers. Subjects were randomized and trained on appropriate laparoscopic camera skills, instrument handling, object positioning, dissection, ligation, suturing, and knot tying. Students within one group were not allowed to practice, learn or train on the opposing trainers. At time points 0, 2, and 6 months all subjects completed a series of laparoscopic exercises in a live porcine model, which were captured on DVD and scored by blinded expert investigators. AB - RESULTS: Scores improved overall from the pretest to subsequent tests after training with no difference between the virtual reality and box simulator groups. In the medical students specifically, there was overall improvement, and improvement in the needle-transfer and knot-tying skills specifically, with no difference between the box simulator and virtual reality groups. For the interns, both groups showed significant overall improvement with no difference between the virtual reality and box simulator groups or on individual skills. AB - CONCLUSIONS: We conclude that laparoscopic simulator training improves surgical skills in novice trainees. We found both the box trainers and the virtual reality simulators are equally effective means of teaching laparoscopic skills to novice learners. AB - Copyright © 2011 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved. ES - 1878-7452 IL - 1878-7452 DI - S1931-7204(11)00059-6 DO - https://dx.doi.org/10.1016/j.jsurg.2011.02.007 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 21708364 [pubmed] ID - S1931-7204(11)00059-6 [pii] ID - 10.1016/j.jsurg.2011.02.007 [doi] PP - ppublish PH - 2011/01/02 [received] PH - 2011/02/14 [revised] PH - 2011/02/15 [accepted] LG - English EP - 20110504 DP - 2011 Jul-Aug DC - 20110628 EZ - 2011/06/29 06:00 DA - 2011/12/13 00:00 DT - 2011/06/29 06:00 YR - 2011 ED - 20111121 RD - 20110628 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21708364 <383. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 22053253 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - PubMed-not-MEDLINE AU - Sa-Ngasoongsong P AU - Channoom T AU - Kawinwonggowit V AU - Woratanarat P AU - Chanplakorn P AU - Wibulpolprasert B AU - Wongsak S AU - Udomsubpayakul U AU - Wechmongkolgorn S AU - Lekpittaya N FA - Sa-Ngasoongsong, Paphon FA - Channoom, Thanaphot FA - Kawinwonggowit, Viroj FA - Woratanarat, Patarawan FA - Chanplakorn, Pongsthorn FA - Wibulpolprasert, Bussanee FA - Wongsak, Siwadol FA - Udomsubpayakul, Umaporn FA - Wechmongkolgorn, Supaporn FA - Lekpittaya, Nantaporn IN - Sa-Ngasoongsong, Paphon. Department of Orthopaedics. TI - Postoperative blood loss reduction in computer-assisted surgery total knee replacement by low dose intra-articular tranexamic acid injection together with 2-hour clamp drain: a prospective triple-blinded randomized controlled trial. SO - Orthopedic Reviews. 3(2):e12, 2011 AS - Orthop Rev (Pavia). 3(2):e12, 2011 NJ - Orthopedic reviews PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101524779 IO - Orthop Rev (Pavia) PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206515 CP - Italy KW - blood loss.; computer assisted surgery; intra-articular; total knee replacement; tranexamic acid AB - A high-dose local tranexamic acid has been introduced in total knee arthroplasty for bleeding control. We are not sure about the systemic absorption and side effects. The aim of this study was to evaluate the effect of low dosage of intra-articular tranexamic acid injection combined with 2-hour clamp drain in minimally bleeding computer-assisted surgery total knee replacement (CAS-TKR). A prospective randomized controlled trial was conducted in a total of 48 patients underwent CAS-TKR. The patients were randomly assigned to receive either of a mixed intra-articular solution of tranexamic acid 250 mg with physiologic saline (TXA group), or physiologic saline (control group) and then followed by clamp drain for 2 hours. Postoperative blood loss was measured by three different methods as drainage volume, total hemoglobin loss and calculated total blood loss. Transfusion requirement and postoperative complications were recorded. All patients were screened for deep vein thrombosis and the functional outcomes were evaluated at 6 months after surgery. The mean postoperative drainage volume, total hemoglobin loss and calculated total blood loss in TXA group were 308.8 mL, 2.1 g/dL and 206.3 mL compared to 529.0 mL, 3.0 g/dL and 385.1 mL in the control group (P=0.0003, 0.0005 and <0.0001 respectively). Allogenic blood transfusion was needed for one patient (4.2%) in TXA group and for eight patients (33.3%) in the control group. Postoperative knee scores were not significantly different between groups. No deep vein thrombosis, infection or wound complication was detected in both groups. In this study, low dose intra-articular tranexamic acid injection combined with 2-hour clamping drain was effective for reducing postoperative blood loss and transfusion requirement in CAS-TKR without significant difference in postoperative complications or functional outcomes. ES - 2035-8164 IL - 2035-8164 DI - or.2011.e12 DO - https://dx.doi.org/10.4081/or.2011.e12 PT - Journal Article ID - 22053253 [pubmed] ID - 10.4081/or.2011.e12 [doi] ID - or.2011.e12 [pii] ID - PMC3206515 [pmc] PP - ppublish PH - 2011/08/11 [received] PH - 2011/09/09 [accepted] LG - English EP - 20110629 DP - 2011 DC - 20111104 EZ - 2011/11/05 06:00 DA - 2011/11/05 06:01 DT - 2011/11/05 06:00 YR - 2011 ED - 20111110 RD - 20130719 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=22053253 <384. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21782218 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sammon J AU - Kim TK AU - Trinh QD AU - Bhandari A AU - Kaul S AU - Sukumar S AU - Rogers CG AU - Peabody JO FA - Sammon, Jesse FA - Kim, Tae-Kyung FA - Trinh, Quoc-Dien FA - Bhandari, Akshay FA - Kaul, Sanjeev FA - Sukumar, Shyam FA - Rogers, Craig G FA - Peabody, James O IN - Sammon, Jesse. Vattikuti Urology Institute, Henry Ford Hospital, Detroit, Michigan 48202, USA. jsammon79@gmail.com TI - Anastomosis during robot-assisted radical prostatectomy: randomized controlled trial comparing barbed and standard monofilament suture. CM - Comment in: Urology. 2011 Sep;78(3):579-80; author reply 580; PMID: 21884906 SO - Urology. 78(3):572-9, 2011 Sep AS - Urology. 78(3):572-9, 2011 Sep NJ - Urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Aged MH - Anastomosis, Surgical MH - Dioxanes MH - Humans MH - Male MH - Middle Aged MH - Polyesters MH - Polymers MH - Postoperative Complications MH - *Prostatectomy MH - *Robotics MH - Surveys and Questionnaires MH - Suture Techniques MH - *Sutures MH - *Urethra/su [Surgery] MH - *Urinary Bladder/su [Surgery] MH - Urination Disorders/et [Etiology] AB - OBJECTIVE: To compare perioperative and functional outcomes after urethrovesical anastomosis (UVA) with barbed polyglyconate and monofilament poliglecaprone in robot-assisted radical prostatectomy (RARP). Barbed polyglyconate suture was first used for the UVA during RARP beginning in January 2010; safety and feasibility were previously demonstrated in 51 patients. AB - METHODS: From May to September 2010, 64 patients meeting all the inclusion criteria participated in the present multisurgeon prospective, randomized, controlled trial and underwent posterior repair and UVA during RARP with either barbed polyglyconate (n=33) or monofilament poliglecaprone (n=31) suture. The primary outcomes were the anastomotic (UVA) and posterior reconstruction times. Secondary outcomes included cystogram leak, bladder neck reconstruction rate, and 6-week functional outcomes assessed by a self-administered validated patient questionnaire. AB - RESULTS: Posterior reconstruction was performed within 3.3 minutes with the barbed suture versus 4.3 minutes with the monofilament poliglecaprone suture (23.3% reduction) and UVA within 10.1 versus 13.8 minutes, respectively (26.8% reduction). The absolute time difference for the 2-layer anastomosis was 4.7 minutes (a 26.0% reduction in the total anastomosis time). All other perioperative outcomes were equivalent between the 2 groups. Urinary functional outcomes, including the pad use and leakage rates, were equivalent at 6 weeks. AB - CONCLUSION: Anastomosis during RARP with the V-Loc barbed suture can be performed safely and more efficiently than with standard monofilament suture. We demonstrated a 26% decrease in the anastomotic time with no increase in the adverse events, no instances of urinary retention and equivalent functional outcomes were measured with the self-administered patient questionnaire. AB - Copyright © 2011 Elsevier Inc. All rights reserved. RN - 0 (Dioxanes) RN - 0 (Polyesters) RN - 0 (Polymers) RN - 41706-81-4 (glycolide E-caprolactone copolymer) RN - 75734-93-9 (polyglyconate) ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(11)00533-4 DO - https://dx.doi.org/10.1016/j.urology.2011.03.069 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 21782218 [pubmed] ID - S0090-4295(11)00533-4 [pii] ID - 10.1016/j.urology.2011.03.069 [doi] PP - ppublish PH - 2010/12/26 [received] PH - 2011/03/17 [revised] PH - 2011/03/26 [accepted] LG - English EP - 20110722 DP - 2011 Sep DC - 20110902 EZ - 2011/07/26 06:00 DA - 2011/11/09 06:00 DT - 2011/07/26 06:00 YR - 2011 ED - 20111108 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21782218 <385. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21184110 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Stefanidis D AU - Hope WW AU - Scott DJ FA - Stefanidis, Dimitrios FA - Hope, William W FA - Scott, Daniel J IN - Stefanidis, Dimitrios. Department of General Surgery, Carolinas Medical Center, 1000 Blythe Blvd., MEB 601, Charlotte, NC 28203, USA. Dimitrios.Stefanidis@Carolinashealthcare.org TI - Robotic suturing on the FLS model possesses construct validity, is less physically demanding, and is favored by more surgeons compared with laparoscopy. SO - Surgical Endoscopy. 25(7):2141-6, 2011 Jul AS - Surg Endosc. 25(7):2141-6, 2011 Jul NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adult MH - *Attitude of Health Personnel MH - *Clinical Competence MH - *Education, Medical, Continuing/og [Organization & Administration] MH - Female MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - *Robotics/mt [Methods] MH - Surveys and Questionnaires MH - *Suture Techniques/is [Instrumentation] MH - Workload AB - BACKGROUND: The value of robotic assistance for intracorporeal suturing is not well defined. We compared robotic suturing with laparoscopic suturing on the FLS model with a large cohort of surgeons. AB - METHODS: Attendees (n=117) at the SAGES 2006 Learning Center robotic station placed intracorporeal sutures on the FLS box-trainer model using conventional laparoscopic instruments and the da Vinci robot. Participant performance was recorded using a validated objective scoring system, and a questionnaire regarding demographics, task workload, and suturing modality preference was completed. Construct validity for both tasks was assessed by comparing the performance scores of subjects with various levels of experience. A validated questionnaire was used for workload measurement. AB - RESULTS: Of the participants, 84% had prior laparoscopic and 10% prior robotic suturing experience. Within the allotted time, 83% of participants completed the suturing task laparoscopically and 72% with the robot. Construct validity was demonstrated for both simulated tasks according to the participants' advanced laparoscopic experience, laparoscopic suturing experience, and self-reported laparoscopic suturing ability (p<0.001 for all) and according to prior robotic experience, robotic suturing experience, and self-reported robotic suturing ability (p<0.001 for all), respectively. While participants achieved higher suturing scores with standard laparoscopy compared with the robot (84+/-75 vs. 56+/-63, respectively; p<0.001), they found the laparoscopic task more physically demanding (NASA score 13+/-5 vs. 10+/-5, respectively; p<0.001) and favored the robot as their method of choice for intracorporeal suturing (62 vs. 38%, respectively; p<0.01). AB - CONCLUSIONS: Construct validity was demonstrated for robotic suturing on the FLS model. Suturing scores were higher using standard laparoscopy likely as a result of the participants' greater experience with laparoscopic suturing versus robotic suturing. Robotic assistance decreases the physical demand of intracorporeal suturing compared with conventional laparoscopy and, in this study, was the preferred suturing method by most surgeons. Curricula for robotic suturing training need to be developed. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-010-1512-1 PT - Journal Article PT - Randomized Controlled Trial ID - 21184110 [pubmed] ID - 10.1007/s00464-010-1512-1 [doi] PP - ppublish PH - 2009/11/20 [received] PH - 2010/05/23 [accepted] LG - English EP - 20101224 DP - 2011 Jul DC - 20110616 EZ - 2010/12/25 06:00 DA - 2011/11/04 06:00 DT - 2010/12/25 06:00 YR - 2011 ED - 20111102 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21184110 <386. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21703048 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Engel JD FA - Engel, Jason Douglas IN - Engel, Jason Douglas. Department of Urology, George Washington University Hospital, Washington, DC 20006, USA. TI - Effect on sexual function of a vacuum erection device post-prostatectomy. SO - Canadian Journal of Urology. 18(3):5721-5, 2011 Jun AS - Can J Urol. 18(3):5721-5, 2011 Jun NJ - The Canadian journal of urology PI - Journal available in: Print PI - Citation processed from: Internet JC - 9515842, dyg IO - Can J Urol SB - Index Medicus CP - Canada MH - Adult MH - Carbolines/pd [Pharmacology] MH - Carbolines/tu [Therapeutic Use] MH - Combined Modality Therapy MH - Equipment and Supplies MH - *Erectile Dysfunction/et [Etiology] MH - *Erectile Dysfunction/th [Therapy] MH - Humans MH - Male MH - Middle Aged MH - Patient Compliance MH - Penile Erection/de [Drug Effects] MH - Penile Erection/ph [Physiology] MH - Phosphodiesterase 5 Inhibitors/pd [Pharmacology] MH - Phosphodiesterase 5 Inhibitors/tu [Therapeutic Use] MH - *Prostatectomy/ae [Adverse Effects] MH - Sexual Behavior/de [Drug Effects] MH - *Sexual Behavior/ph [Physiology] MH - Sexuality/de [Drug Effects] MH - *Sexuality/ph [Physiology] MH - Tadalafil MH - Treatment Outcome MH - *Vacuum AB - INTRODUCTION: Treatment of erectile dysfunction (ED) subsequent to bilateral nerve sparing robotic prostatectomy (BNSRP) with tadalafil plus a vacuum erection device (VED) may improve return of sexual function. AB - MATERIALS AND METHODS: Men with prostate cancer who had BNSRP were randomized to receive tadalafil, 20 mg three times weekly, or tadalafil plus a VED, 10 minutes unbanded per day for at least 5 days weekly. Treatments started 1 month after surgery; clinic visits were at 1, 3, 6, 9 and 12 months. Patients were requested to attempt intercourse at least twice before each visit. At every visit patients completed the International Index of Erectile Function (IIEF-5) questionnaire and a penile hardness scale (1-4) and were questioned as to their ability to have vaginal penetration and intercourse to orgasm. AB - RESULTS: Thirteen men started the combination regimen, and there were no dropouts; 10 patients started the tadalafil treatment, and three men dropped out. The mean IIEF-5 at months 6, 9 and 12 were significantly higher for the combination group, while the penile hardness scores were significantly greater for the combination group at 6 and 9 months. After 12 months 92% of combination patients responded yes to the vaginal penetration question versus 57% of the tadalafil group; corresponding figures were 92% and 29%, respectively, for intercourse to orgasm. Compliance to the VED was superior to that of tadalafil. AB - CONCLUSION: Men with ED subsequent to BNSRP had a more rapid and complete return of sexual function when treated with tadalafil plus VED versus tadalafil alone. RN - 0 (Carbolines) RN - 0 (Phosphodiesterase 5 Inhibitors) RN - 742SXX0ICT (Tadalafil) IS - 1195-9479 IL - 1195-9479 PT - Journal Article PT - Randomized Controlled Trial ID - 21703048 [pubmed] PP - ppublish LG - English DP - 2011 Jun DC - 20110627 EZ - 2011/06/28 06:00 DA - 2011/11/01 06:00 DT - 2011/06/28 06:00 YR - 2011 ED - 20111031 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21703048 <387. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21640696 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - PubMed-not-MEDLINE AU - Coelho RF AU - Chauhan S AU - Patel VR FA - Coelho, Rafael Ferreira FA - Chauhan, Sanket FA - Patel, Vipul R IN - Coelho, Rafael Ferreira. Global Robotics Institute, Florida Hospital Celebration Health, Celebration, Fl, USA. coelhouro@yahoo.com.br TI - Re: Posterior rhabdosphincter reconstruction during robotic assisted radical prostatectomy: results from a phase II randomized clinical trial. CM - Comment on: J Urol. 2011 Apr;185(4):1262-7; PMID: 21334025 SO - European Urology. 60(1):180-1, 2011 Jul AS - Eur Urol. 60(1):180-1, 2011 Jul NJ - European urology PI - Journal available in: Print PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. CP - Switzerland ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(11)00386-1 DO - https://dx.doi.org/10.1016/j.eururo.2011.04.018 PT - Comment PT - Journal Article ID - 21640696 [pubmed] ID - S0302-2838(11)00386-1 [pii] ID - 10.1016/j.eururo.2011.04.018 [doi] PP - ppublish LG - English DP - 2011 Jul DC - 20110606 EZ - 2011/06/07 06:00 DA - 2011/06/07 06:01 DT - 2011/06/07 06:00 YR - 2011 ED - 20111004 RD - 20110606 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=21640696 <388. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21546874 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lau S AU - Buzaglo K AU - Vaknin Z AU - Brin S AU - Kaufer R AU - Drummond N AU - Gourdji I AU - Aubin S AU - Rosberger Z AU - Gotlieb WH FA - Lau, Susie FA - Buzaglo, Karen FA - Vaknin, Zvi FA - Brin, Sonya FA - Kaufer, Rebecca FA - Drummond, Nancy FA - Gourdji, Iris FA - Aubin, Sylvie FA - Rosberger, Zeev FA - Gotlieb, Walter H IN - Lau, Susie. Division of Gynecologic Oncology, Segal Cancer Center, Jewish General Hospital, McGill University, Montreal, Quebec, Canada. TI - Relationship between body mass index and robotic surgery outcomes of women diagnosed with endometrial cancer. SO - International Journal of Gynecological Cancer. 21(4):722-9, 2011 May AS - Int J Gynecol Cancer. 21(4):722-9, 2011 May NJ - International journal of gynecological cancer : official journal of the International Gynecological Cancer Society PI - Journal available in: Print PI - Citation processed from: Internet JC - dzp, 9111626 IO - Int. J. Gynecol. Cancer SB - Index Medicus CP - United States MH - Aged MH - *Body Mass Index MH - Carcinoma/co [Complications] MH - Carcinoma/di [Diagnosis] MH - *Carcinoma/su [Surgery] MH - Endometrial Neoplasms/co [Complications] MH - Endometrial Neoplasms/di [Diagnosis] MH - *Endometrial Neoplasms/su [Surgery] MH - Female MH - Gynecologic Surgical Procedures/ae [Adverse Effects] MH - Gynecologic Surgical Procedures/is [Instrumentation] MH - *Gynecologic Surgical Procedures/mt [Methods] MH - Humans MH - Ideal Body Weight/ph [Physiology] MH - Middle Aged MH - Obesity/co [Complications] MH - Obesity/su [Surgery] MH - Obesity, Morbid/co [Complications] MH - Obesity, Morbid/su [Surgery] MH - Perioperative Period/ae [Adverse Effects] MH - Postoperative Complications/ep [Epidemiology] MH - Postoperative Complications/et [Etiology] MH - *Robotics/mt [Methods] MH - Treatment Outcome MH - Wounds and Injuries/ep [Epidemiology] MH - Wounds and Injuries/et [Etiology] AB - OBJECTIVE: This is a prospective evaluation of the outcome of minimal invasive surgery using robotics in function of the body mass index (BMI) of patients. AB - METHODS: This is a prospective cohort study of consecutive women undergoing surgery for endometrial cancer at a tertiary care facility since the initiation of a robotic program in December 2007. Surgical and personal outcome variables as well as quality of life and postoperative recovery were assessed using a combination of objective and subjective/self-report questionnaires. Women were divided into 3 groups based on their BMI. Comparative analyses among nonobese (n = 52), obese (n = 33) and morbidly obese (n = 23) women were performed on the outcome measures after surgery. AB - RESULTS: The mean BMI and the range in each of the BMI categories was 25 kg/m2 (18.7-29.4 kg/m2), 34 kg/m2 (30.1-38.4 kg/m2), and 46 kg/m2 (40.0-58.8 kg/m2). Women with higher BMI tended to be more frequently affected with comorbidities such as diabetes (15.4%, 26.0%, and 27.3%, respectively; P = 0.32) and hypertension (55.8%, 69.6%, and 69.7%, respectively; P = 0.19). Despite these differences, surgical console time (P = 0.20), major postoperative complications (P = 0.52), overall wound complications (P = 0.18), and median length of hospitalization in days (P = 0.17) were not statistically different among the 3 groups. Only 5.6% of women needed a mini laparotomy all of which were performed for the removal of their enlarged uterus, which could not be delivered safely via the vagina, at the end of the surgical procedure. There was no increased conversion to laparotomy due to increased BMI. Women in all 3 groups reported rapid resumption of hygiene regimens and chores, little need for narcotic analgesia, and high satisfaction with the procedure. AB - CONCLUSIONS: Obese and morbidly obese patients with endometrial cancer are also good candidates for robotic surgery. These women benefit considerably from minimal invasive surgery and have little perioperative complications. ES - 1525-1438 IL - 1048-891X DI - 00009577-201105000-00022 DO - https://dx.doi.org/10.1097/IGC.0b013e318212981d PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 21546874 [pubmed] ID - 10.1097/IGC.0b013e318212981d [doi] ID - 00009577-201105000-00022 [pii] PP - ppublish LG - English DP - 2011 May DC - 20110506 EZ - 2011/05/07 06:00 DA - 2011/10/01 06:00 DT - 2011/05/07 06:00 YR - 2011 ED - 20110930 RD - 20110506 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21546874 <389. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21658752 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Subramaniam A AU - Kim KH AU - Bryant SA AU - Zhang B AU - Sikes C AU - Kimball KJ AU - Kilgore LC AU - Huh WK AU - Straughn JM Jr AU - Alvarez RD FA - Subramaniam, Akila FA - Kim, Kenneth H FA - Bryant, Shannon A FA - Zhang, Bin FA - Sikes, Christa FA - Kimball, Kristopher J FA - Kilgore, Larry C FA - Huh, Warner K FA - Straughn, John M Jr FA - Alvarez, Ronald D IN - Subramaniam, Akila. Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL 35223, USA. akila.subramaniam@gmail.com TI - A cohort study evaluating robotic versus laparotomy surgical outcomes of obese women with endometrial carcinoma. SO - Gynecologic Oncology. 122(3):604-7, 2011 Sep AS - Gynecol Oncol. 122(3):604-7, 2011 Sep NJ - Gynecologic oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - fxc, 0365304 IO - Gynecol. Oncol. SB - Index Medicus CP - United States MH - Cohort Studies MH - *Endometrial Neoplasms/co [Complications] MH - *Endometrial Neoplasms/su [Surgery] MH - Female MH - Gynecologic Surgical Procedures/mt [Methods] MH - Humans MH - Laparotomy/mt [Methods] MH - Middle Aged MH - *Obesity/co [Complications] MH - Obesity/pp [Physiopathology] MH - Retrospective Studies MH - Robotics/mt [Methods] MH - Treatment Outcome AB - OBJECTIVE: Minimally invasive surgery offers advantages for management of obese patients, but technical difficulty often deters its utilization. Compared to laparotomy, robotic surgery should allow comparable staging and improved surgical outcomes. Therefore, we evaluated outcomes in robotic and laparotomy cohorts of obese women with endometrial cancer at our institution. AB - METHODS: Retrospective robotic and laparotomy cohorts of obese women (BMI > 30 kg/m(2)) undergoing surgical management of primary endometrial cancer from March 2006 to March 2009 were formulated utilizing a computerized database. Patient demographics, operative statistics, peri-operative complications, and pathologic details were collected in an intent to treat analysis. Chi-square or Fisher's exact test and t-test were used for statistical analysis. AB - RESULTS: 73 women underwent robotic surgical management, 11% converted to laparotomy. Mean BMI (39.8 vs. 41.9, p=0.152), number of co-morbidities (2.49 vs. 2.62, p=0.690), number of previous surgeries (0.97 vs. 0.94, p=0.841), and lymphadenectomies performed (65.8% vs. 56.7%, p=0.227) were similar between cohorts. Total lymph nodes obtained were not statistically different between cohorts (8.01 vs. 7.24, p=0.505). Total operative time and room time was significantly longer for robotic surgery; however, estimated blood loss, the percentage of patients receiving transfusion, hospital length of stay, wound complications (4.1% vs. 20.2%, p=0.002) and other complications (9.6% vs. 29.8%, p=0.001) were improved for the robotic cohort. AB - CONCLUSIONS: Robotic management of obese women with endometrial cancer yields acceptable staging results and improved surgical outcomes. Although operating time is longer, hospital time is shorter. Robotic surgery may be an ideal approach for these patients. AB - Copyright © 2011 Elsevier Inc. All rights reserved. ES - 1095-6859 IL - 0090-8258 DI - S0090-8258(11)00421-5 DO - https://dx.doi.org/10.1016/j.ygyno.2011.05.024 PT - Journal Article ID - 21658752 [pubmed] ID - S0090-8258(11)00421-5 [pii] ID - 10.1016/j.ygyno.2011.05.024 [doi] PP - ppublish PH - 2011/02/14 [received] PH - 2011/05/15 [revised] PH - 2011/05/18 [accepted] LG - English EP - 20110611 DP - 2011 Sep DC - 20110808 EZ - 2011/06/11 06:00 DA - 2011/09/29 06:00 DT - 2011/06/11 06:00 YR - 2011 ED - 20110926 RD - 20110808 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21658752 <390. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21377341 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Choi EM AU - Na S AU - Choi SH AU - An J AU - Rha KH AU - Oh YJ FA - Choi, Eun Mi FA - Na, Sungwon FA - Choi, Seung Ho FA - An, Jiwon FA - Rha, Koon Ho FA - Oh, Young Jun IN - Choi, Eun Mi. Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul 120-752, Korea. TI - Comparison of volume-controlled and pressure-controlled ventilation in steep Trendelenburg position for robot-assisted laparoscopic radical prostatectomy. SO - Journal of Clinical Anesthesia. 23(3):183-8, 2011 May AS - J Clin Anesth. 23(3):183-8, 2011 May NJ - Journal of clinical anesthesia PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - an9, 8812166 IO - J Clin Anesth SB - Index Medicus CP - United States MH - Aged MH - *Head-Down Tilt MH - Hemodynamics MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - Pneumoperitoneum, Artificial MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Respiration, Artificial/mt [Methods] MH - Respiratory Mechanics MH - *Robotics/mt [Methods] AB - STUDY OBJECTIVE: To compare the effects of volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) on respiratory mechanics and hemodynamics in steep Trendelenburg position. AB - DESIGN: Prospective, randomized clinical trial. AB - SETTING: University hospital. AB - PATIENTS: 34 ASA physical status 1 and 2 patients undergoing RLRP. AB - INTERVENTIONS: Patients were randomly allocated to either the VCV (n = 17) or the PCV group (n = 17). After induction of anesthesia, each patient's lungs were ventilated in constant-flow VCV mode with 50% O(2) and tidal volume of 8 mL/kg; a pulmonary artery catheter was then inserted. After establishment of 30degree Trendelenburg position and pneumoperitoneum, VCV mode was switched to PCV mode in the PCV group. AB - MEASUREMENTS: Respiratory and hemodynamic variables were measured at baseline supine position (T1), post-Trendelenburg and pneumoperitoneum 60 minutes (T2) and 120 minutes (T3), and return to baseline after skin closure (T4). AB - MAIN RESULTS: The PCV group had lower peak airway pressure (AP(peak)) and greater dynamic compliance (C(dyn)) than the VCV group at T2 and T3 (P < 0.05). However, no other variables differed between the groups. Pulmonary arterial pressure and central venous pressure increased at T2 and T3 (P < 0.05). Cardiac output and right ventricular ejection fraction were unchanged in both groups. AB - CONCLUSIONS: PCV offered greater C(dyn) and lower AP(peak) than VCV, but no advantages over VCV in respiratory mechanics or hemodynamics. AB - Copyright © 2011 Elsevier Inc. All rights reserved. ES - 1873-4529 IL - 0952-8180 DI - S0952-8180(11)00043-2 DO - https://dx.doi.org/10.1016/j.jclinane.2010.08.006 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 21377341 [pubmed] ID - S0952-8180(11)00043-2 [pii] ID - 10.1016/j.jclinane.2010.08.006 [doi] PP - ppublish PH - 2009/08/07 [received] PH - 2010/07/26 [revised] PH - 2010/08/11 [accepted] LG - English EP - 20110304 DP - 2011 May DC - 20110516 EZ - 2011/03/08 06:00 DA - 2011/09/29 06:00 DT - 2011/03/08 06:00 YR - 2011 ED - 20110926 RD - 20110516 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21377341 <391. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20700654 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Douaihy YE AU - Sooriakumaran P AU - Agarwal M AU - Srivastava A AU - Grover S AU - Mudaliar K AU - Rajan S AU - Lawlor A AU - Leung R AU - Tewari A FA - Douaihy, Youssef El FA - Sooriakumaran, Prasanna FA - Agarwal, Mayank FA - Srivastava, Abhishek FA - Grover, Sonal FA - Mudaliar, Kumaran FA - Rajan, Sivaram FA - Lawlor, Amanda FA - Leung, Robert FA - Tewari, Ashutosh IN - Douaihy, Youssef El. Lefrak Robotic Institute, Weill Cornell Medical College, New York, 525 East 68th Street, Box 94, New York, NY 10065, USA. yoe2002@med.cornell.edu TI - A cohort study investigating patient expectations and satisfaction outcomes in men undergoing robotic assisted radical prostatectomy. SO - International Urology & Nephrology. 43(2):405-15, 2011 Jun AS - Int Urol Nephrol. 43(2):405-15, 2011 Jun NJ - International urology and nephrology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - guq, 0262521 IO - Int Urol Nephrol SB - Index Medicus CP - Netherlands MH - Adult MH - Aged MH - Aged, 80 and over MH - Cohort Studies MH - Humans MH - Male MH - Middle Aged MH - *Patient Satisfaction MH - *Prostatectomy/mt [Methods] MH - Retrospective Studies MH - *Robotics MH - Surveys and Questionnaires AB - INTRODUCTION: Robotic assisted radical prostatectomy (RARP) is gaining widespread acceptance for the management of localized prostate cancer. However, data regarding patient expectations and satisfaction outcomes after RARP are scarce. AB - METHODS: We developed a structured program for preoperative education and evidence-based counseling using a multi-disciplinary team approach and measured its impact on patient satisfaction in a cohort of 377 consecutive patients who underwent RARP at our institution. Responses regarding overall, sexual, and continence satisfaction were assessed. AB - RESULTS: Fifty percent of our patient cohort replied to the questionnaire assessments. Ninety-three percent of responding patients expressed overall satisfaction after RARP with only 0.5% expressing regret at having had the operation. Biochemical recurrence and lack of continence correlated significantly with low levels of satisfaction, though sexual function was not significantly different among those satisfied and those not. Most patients (97%) valued oncologic outcome as their top priority, with regaining of urinary control being the commonest second priority (60%). AB - CONCLUSIONS: RARP appears to be associated with a high degree of patient satisfaction in a cohort of patients subjected to a structured preoperative education and counseling program. Oncologic outcomes are most important to these patients and have the largest influence on satisfaction scores. ES - 1573-2584 IL - 0301-1623 DO - https://dx.doi.org/10.1007/s11255-010-9817-5 PT - Journal Article ID - 20700654 [pubmed] ID - 10.1007/s11255-010-9817-5 [doi] PP - ppublish PH - 2010/06/08 [received] PH - 2010/07/09 [accepted] LG - English EP - 20100811 DP - 2011 Jun DC - 20110516 EZ - 2010/08/12 06:00 DA - 2011/09/29 06:00 DT - 2010/08/12 06:00 YR - 2011 ED - 20110923 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=20700654 <392. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19892506 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Platz E AU - Liteplo A AU - Hurwitz S AU - Hwang J FA - Platz, Elke FA - Liteplo, Andrew FA - Hurwitz, Shelley FA - Hwang, James IN - Platz, Elke. Department of Emergency Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA. TI - Are live instructors replaceable? Computer vs. classroom lectures for EFAST training. SO - Journal of Emergency Medicine. 40(5):534-8, 2011 May AS - J Emerg Med. 40(5):534-8, 2011 May NJ - The Journal of emergency medicine PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - ibo, 8412174 IO - J Emerg Med SB - Index Medicus CP - United States MH - Adult MH - *Computer-Assisted Instruction/mt [Methods] MH - *Education, Medical, Graduate/mt [Methods] MH - Educational Measurement MH - *Emergency Medicine/ed [Education] MH - Female MH - *General Surgery/ed [Education] MH - Hospitals, Teaching MH - Humans MH - Internship and Residency MH - Male MH - *Teaching/mt [Methods] MH - *Ultrasonography AB - BACKGROUND: The EFAST (extended focused assessment with sonography for trauma) is part of the recommended curriculum for Emergency Medicine and Surgery residents. Computer-based lectures may represent a time-efficient alternative to traditional lectures. AB - OBJECTIVES: Our hypothesis was that computer lectures in basic ultrasound and the EFAST are not inferior to classroom lectures in test score improvement for residents with or without prior training. AB - METHODS: First-year Emergency Medicine and Surgery residents were enrolled and completed a pre-test. Subjects were then randomized into a classroom group, which attended traditional lectures, and a computer group, which listened to narrated lectures on computers. After the didactic training, all subjects completed a post-test. AB - RESULTS: Forty-four subjects completed the study: 64% were General Surgery residents, 66% were male. Overall, mean test score improvements were higher in the classroom than in the computer group (28.0% vs. 18.4%). In 25 residents without prior training, mean improvements in the computer and classroom groups were 25% and 27%, respectively. The 95% confidence limit around the difference was 9%, falling within the a priori non-inferiority range of 10%, and consistent with non-inferiority of computer-based lectures. In 19 residents with prior training, mean test score improvements for the computer and classroom groups were 13% and 29%, respectively. The 95% confidence limit of 24% exceeded the non-inferiority range, consistent with inferiority of computer-based lectures. AB - CONCLUSIONS: Computer-based lectures are not inferior to classroom lectures and may represent a worthwhile substitution in subjects without prior ultrasound education. Our data suggest that didactic ultrasound training through classroom lectures is more effective than computer-based lectures in individuals with prior training. AB - Copyright © 2011 Elsevier Inc. All rights reserved. IS - 0736-4679 IL - 0736-4679 DI - S0736-4679(09)00755-0 DO - https://dx.doi.org/10.1016/j.jemermed.2009.08.030 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 19892506 [pubmed] ID - S0736-4679(09)00755-0 [pii] ID - 10.1016/j.jemermed.2009.08.030 [doi] PP - ppublish PH - 2009/04/04 [received] PH - 2009/08/14 [revised] PH - 2009/08/30 [accepted] LG - English EP - 20091105 DP - 2011 May DC - 20110516 EZ - 2009/11/07 06:00 DA - 2011/09/23 06:00 DT - 2009/11/07 06:00 YR - 2011 ED - 20110922 RD - 20111027 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=19892506 <393. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21443432 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ayloo S AU - Buchs NC AU - Addeo P AU - Bianco FM AU - Giulianotti PC FA - Ayloo, Subhashini FA - Buchs, Nicolas C FA - Addeo, Pietro FA - Bianco, Francesco M FA - Giulianotti, Pier C IN - Ayloo, Subhashini. Division of General, Minimally Invasive, and Robotic Surgery, Department of Surgery, University of Illinois at Chicago, Chicago, Illinois 60612, USA. ayloosub@uic.edu TI - Robot-assisted sleeve gastrectomy for super-morbidly obese patients. SO - Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A. 21(4):295-9, 2011 May AS - J Laparoendosc Adv Surg Tech A. 21(4):295-9, 2011 May NJ - Journal of laparoendoscopic & advanced surgical techniques. Part A PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 9706293, c0d IO - J Laparoendosc Adv Surg Tech A SB - Index Medicus CP - United States MH - Adult MH - Female MH - *Gastrectomy/mt [Methods] MH - Humans MH - Male MH - Middle Aged MH - *Obesity, Morbid/su [Surgery] MH - Prospective Studies MH - *Robotics MH - Young Adult AB - BACKGROUND: Sleeve gastrectomy represents a valid option for morbidly obese patients, either as a primary or as a staged bariatric procedure. Several variations of the technique have been reported. Herein, we report our initial experience with robot-assisted sleeve gastrectomy (RASG). AB - MATERIALS AND METHODS: A prospectively held database for patients who underwent RASG was reviewed. Data included patient demographics, operative parameters, morbidity, and follow-up outcomes. The outcomes after RASG were compared to the laparoscopic approach. AB - RESULTS: From September 2007 to February 2010, 69 morbidly obese patients underwent sleeve gastrectomy. Of these, 30 (43.5%) were robot-assisted and 39 (56.5%) were laparoscopic. There was no statistically significant difference in demographics between the two groups. The RASG group underwent an oversewing of the staple line, and mean operative time was 135 minutes. In the laparoscopic group, where the staple line was not oversewn, mean operative time was 114 minutes (P=.003). Morbidity after RASG was 3.3%, and there were no gastrointestinal leaks or staple line bleeding. Mean postoperative hospital stay after RASG was 2.6 days (range: 1.6-8.3 days). Mean body mass index decrease at 1 year was 16 kg/m(2). There were no differences between the two groups in terms of morbidity, mortality, length of stay, and weight loss. AB - CONCLUSIONS: RASG can be performed safely, with good outcomes. However, the exact role and the advantages of RASG require further study in larger series. ES - 1557-9034 IL - 1092-6429 DO - https://dx.doi.org/10.1089/lap.2010.0398 PT - Clinical Trial PT - Journal Article ID - 21443432 [pubmed] ID - 10.1089/lap.2010.0398 [doi] PP - ppublish LG - English EP - 20110328 DP - 2011 May DC - 20110513 EZ - 2011/03/30 06:00 DA - 2011/09/16 06:00 DT - 2011/03/30 06:00 YR - 2011 ED - 20110915 RD - 20110513 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21443432 <394. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21510804 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Eden CG AU - Arora A AU - Hutton A FA - Eden, Christopher G FA - Arora, Avanish FA - Hutton, Anthony IN - Eden, Christopher G. Department of Urology, The Royal Surrey County Hospital , Guildford, UK. edenchristopher@gmail.com TI - Cancer control, continence, and potency after laparoscopic radical prostatectomy beyond the learning and discovery curves. SO - Journal of Endourology. 25(5):815-9, 2011 May AS - J Endourol. 25(5):815-9, 2011 May NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Demography MH - Humans MH - Inpatients MH - *Laparoscopy MH - *Learning MH - Male MH - Middle Aged MH - Outpatients MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/pp [Physiopathology] MH - Prostatic Neoplasms/pc [Prevention & Control] MH - *Prostatic Neoplasms/su [Surgery] AB - PURPOSE: To investigate the results of laparoscopic radical prostatectomy (LRP) beyond the learning and discovery curves of 700 patients previously reported by the authors for potency. AB - PATIENTS AND METHODS: Five hundred consecutive patients underwent LRP during a 28-month period with a minimum follow-up of 12 months. Median age (with range) = 61.0 (33-76) years; prostate-specific antigen level = 7.0 (1-37); biopsy Gleason sum = 7 (4-10). Clinical stage was T1 in 41.0%, T2 in 54.2%, and T3 in 4.8%. Nerve preservation (NP) was performed bilaterally in 57.9%, unilaterally in 15.3%, and on neither side in 26.8%. AB - RESULTS: Median operative time was 157 (91-331) minutes, with no conversions or intraoperative blood transfusions; 0.4% of patients received a transfusion postoperatively, and 4.2% had complications. There were no rectal injuries. The overall positive margin rate was 13.0% and correlated with pathologic parameters. At a minimum of 1 year follow-up (mean=13.5 (12-36) mos), overall survival was 100%, and biochemical disease-free survival was 98.8%. The pad-free rate was 97.4%. Potency (International Index of Erectile Function-5 score >17) at a mean follow-up of 13.5 months in previously potent men in their 4th, 5th, 6th, and 7th decades after bilateral NP was 100.0%, 91.8%, 82.9%, and 60.0% and after unilateral NP was 100%, 66.7%, 50.1%, and 0.0%. Overall potency after bilateral neurovascular bundle NVB preservation was 86.9%. AB - CONCLUSION: LRP is capable of matching or exceeding the best results for open radical prostatectomy and robot-assisted radical prostatectomy when performed by an experienced surgeon in a high-volume setting. These results suggest that the method used to perform radical prostatectomy is a less important determinant of success than surgical experience. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2010.0451 PT - Clinical Trial PT - Journal Article ID - 21510804 [pubmed] ID - 10.1089/end.2010.0451 [doi] PP - ppublish LG - English EP - 20110421 DP - 2011 May DC - 20110526 EZ - 2011/04/23 06:00 DA - 2011/09/08 06:00 DT - 2011/04/23 06:00 YR - 2011 ED - 20110907 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21510804 <395. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21114412 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Chung JS AU - Kim WT AU - Ham WS AU - Yu HS AU - Chae Y AU - Chung SH AU - Choi YD FA - Chung, Jae Seung FA - Kim, Won Tae FA - Ham, Won Sik FA - Yu, Ho Song FA - Chae, Yunbyung FA - Chung, Seok Hyun FA - Choi, Young Deuk IN - Chung, Jae Seung. Department of Urology, Inje University , Busan, Republic of Korea. TI - Comparison of oncological results, functional outcomes, and complications for transperitoneal versus extraperitoneal robot-assisted radical prostatectomy: a single surgeon's experience. SO - Journal of Endourology. 25(5):787-92, 2011 May AS - J Endourol. 25(5):787-92, 2011 May NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Aged MH - Humans MH - Male MH - Perioperative Care MH - *Peritoneum/su [Surgery] MH - *Postoperative Complications/et [Etiology] MH - *Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/pp [Physiopathology] MH - Prostatic Neoplasms/su [Surgery] MH - *Robotics/mt [Methods] MH - Treatment Outcome AB - BACKGROUND AND PURPOSE: To compare the oncologic results, functional outcomes, and complications of transperitoneal (TP) and extraperitoneal (EP) robotic radical prostatectomy. AB - PATIENTS AND METHODS: From June 2007 to April 2009, 105 patients underwent TP robotic radical prostatectomy, and 155 patients underwent EP robotic radical prostatectomy. Clinicopathological and perioperative data were compared between the two groups. Postoperative complications and functional outcomes including potency and incontinence were assessed. AB - RESULTS: Patient demographics were similar in the TP and EP groups. No significant differences in positive surgical margins were noted between the groups. The total operative time, number of lymph nodes removed, and estimated blood loss were also not significantly different. However, the robot console time was shorter for the EP group than for the TP group (89.1 vs. 107.8 minutes, p=0.03). Postoperative pain scale scores were lower in the EP group than in the TP group (2.7 vs. 6.3, p<0.001). The incidence of ileus and hernia were lower in the EP group; however, the incidence of lymphocele was higher in the EP group. Postoperative potency and continence rates were similar between the groups; however, the EP group had a faster recovery of continence compared with the TP group. AB - CONCLUSIONS: The EP approach has similar oncological and perioperative results, less postoperative pain, less bowel-associated complication, and better functional outcomes than those of the TP approach. The EP approach may be an important alternative in robotic radical prostatectomy. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2010.0222 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 21114412 [pubmed] ID - 10.1089/end.2010.0222 [doi] PP - ppublish LG - English EP - 20101129 DP - 2011 May DC - 20110526 EZ - 2010/12/01 06:00 DA - 2011/09/08 06:00 DT - 2010/12/01 06:00 YR - 2011 ED - 20110907 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21114412 <396. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21324093 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Asimakopoulos AD AU - Pereira Fraga CT AU - Annino F AU - Pasqualetti P AU - Calado AA AU - Mugnier C FA - Asimakopoulos, Anastasios D FA - Pereira Fraga, Clovis T FA - Annino, Filippo FA - Pasqualetti, Patrizio FA - Calado, Adriano A FA - Mugnier, Camille IN - Asimakopoulos, Anastasios D. Department of Surgery, University of Tor Vergata, Policlinico Tor Vergata, Rome, Italy. tasospao2003@yahoo.com TI - Randomized comparison between laparoscopic and robot-assisted nerve-sparing radical prostatectomy. SO - Journal of Sexual Medicine. 8(5):1503-12, 2011 May AS - J Sex Med. 8(5):1503-12, 2011 May NJ - The journal of sexual medicine PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101230693 IO - J Sex Med SB - Index Medicus CP - Netherlands MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/su [Surgery] MH - *Robotics/mt [Methods] MH - Treatment Outcome AB - INTRODUCTION: Lack of randomized controlled trials (RCTs) that compare pure laparoscopic radical prostatectomy (LRP) with robot-assisted laparoscopic radical prostatectomy (RALRP) is an important gap of the literature related to the surgical treatment of the clinically localized prostate cancer (PCa). AB - AIM: To provide the first prospective randomized comparison on the functional and oncological outcomes of LRP and RALRP for the treatment of the clinically localized PCa. AB - METHODS: Between 2007 and 2008, 128 consecutive male patients were randomized in two groups and treated by a single experienced surgeon with traditional LRP (Group I-64 patients) or RALRP (Group II-64 patients) in all cases with intent of bilateral intrafascial nerve sparing. AB - MAIN OUTCOME MEASURES: Primary end point was to compare the 12 months erectile function (EF) outcomes. Complication rates, continence outcomes, and oncological results were also compared. The sample size of our study was able, with an adequate power (1-beta > 0.90), to recognize as significant large differences (above 0.30) between incidence proportions of considered outcomes. AB - RESULTS: No statistically significant differences were observed for operating time, estimated blood loss, transfusion rate, complications, rates of positive surgical margins, rates of biochemical recurrence, continence, and time to continence. However, the 12-month evaluation of capability for intercourse (with or without phosphodiesterase type 5 inhibitors) showed a clear and significant advantage of RALRP (32% vs. 77%, P < 0.0001). Time to capability for intercourse was significantly shorter for RALRP. Rates of return to baseline International Index of Erectile Function (IIEF-6) EF domain score questionnaires (questions 1-5 and 15) (25% vs. 58%) and to IIEF-6 > 17 (38% vs. 63%) were also significantly higher for RALRP (P = 0.0002 and P = 0.008, respectively). AB - CONCLUSIONS: Our study offers the first high-level evidence that RALRP provides significantly better EF recovery than LRP without hindering the oncologic radicality of the procedure. Larger RCTs are needed to confirm if a new gold-standard treatment in the field of RP has risen. AB - Copyright © 2011 International Society for Sexual Medicine. ES - 1743-6109 IL - 1743-6095 DI - S1743-6095(15)33502-5 DO - https://dx.doi.org/10.1111/j.1743-6109.2011.02215.x PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 21324093 [pubmed] ID - 10.1111/j.1743-6109.2011.02215.x [doi] ID - S1743-6095(15)33502-5 [pii] PP - ppublish LG - English EP - 20110216 DP - 2011 May DC - 20110427 EZ - 2011/02/18 06:00 DA - 2011/09/01 06:00 DT - 2011/02/18 06:00 YR - 2011 ED - 20110831 RD - 20110427 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21324093 <397. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20800338 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Cestari A AU - Buffi NM AU - Lista G AU - Sangalli M AU - Scapaticci E AU - Fabbri F AU - Lazzeri M AU - Rigatti P AU - Guazzoni G FA - Cestari, Andrea FA - Buffi, Nicolo Maria FA - Lista, Giuliana FA - Sangalli, Mattia FA - Scapaticci, Emanuele FA - Fabbri, Fabio FA - Lazzeri, Massimo FA - Rigatti, Patrizio FA - Guazzoni, Giorgio IN - Cestari, Andrea. Department of Urology, Vita-Salute University, San Raffaele Hospital-Turro, Milan, Italy. a_cestari@yahoo.it TI - Retroperitoneal and transperitoneal robot-assisted pyeloplasty in adults: techniques and results. SO - European Urology. 58(5):711-8, 2010 Nov AS - Eur Urol. 58(5):711-8, 2010 Nov NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Adult MH - Feasibility Studies MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Patient Positioning/mt [Methods] MH - Peritoneum/su [Surgery] MH - Postoperative Care/mt [Methods] MH - *Retroperitoneal Space/su [Surgery] MH - *Robotics/mt [Methods] MH - Stents MH - Treatment Outcome MH - Ureter/su [Surgery] MH - *Ureteral Obstruction/su [Surgery] MH - Urologic Surgical Procedures/is [Instrumentation] MH - *Urologic Surgical Procedures/mt [Methods] MH - Young Adult AB - BACKGROUND: The surgical management of ureteropelvic junction obstruction (UPJO) has dramatically evolved over the past 20 yr due to the development of new technology. AB - OBJECTIVE: Our aim was to report the feasibility and efficacy of robot-assisted pyeloplasty (RAP) performed by either the retroperitoneal or the transperitoneal approach. AB - DESIGN, SETTING, AND PARTICIPANTS: A stage 2 investigative study was conducted including development (stage 2a) and exploration (stage 2b) of transperitoneal and retroperitoneal RAP performed in 55 patients at an urban tertiary university department of urology. AB - SURGICAL PROCEDURE: Retroperitoneal RAP was performed with the patient in full flank position using a 12-mm Hasson-style optical port at the tip of the 12th rib, plus two operative 8-mm robotic trocars and an assistant 5-mm port. The stenotic ureteropelvic junction was excised, the ureter was spatulated, and a dismembered pyeloplasty was performed in all cases. Transperitoneal RAP was performed with the patients in the 60degree flank position. The optical port is in the umbilical area, plus two 8-mm operative robotic ports and one 5-mm assistant port. The pyeloplasty technique is similar to the retroperitoneoscopic approach. In both groups, the stent can be positioned in an anterograde or retrograde fashion. AB - MEASUREMENTS: Success consisted of no evidence of obstruction on computed tomography urography or mercaptoacetyltriglycine-3 diuretic renal scan, no postoperative symptoms, and no further treatment. AB - RESULTS AND LIMITATIONS: Thirty-six patients underwent retroperitoneoscopic RAP and 19 transperitoneal RAP for UPJO. All the procedures were completed with robotic assistance. The overall objective success (measured by diuretic renal scan and/or imaging techniques) was 96% with two cases of recurrence (both in the retroperitoneal group). The main limitation was the short follow-up, although all patients reached at least a 6-mo follow-up. AB - CONCLUSIONS: RAP performed either retroperitoneally or transperitoneally was revealed as a feasible and reproducible surgical option for the treatment of UPJO, offering a subjective optimal plasty reconfiguration at short follow-up. AB - Copyright © 2010 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(10)00681-0 DO - https://dx.doi.org/10.1016/j.eururo.2010.07.020 PT - Clinical Trial, Phase II PT - Journal Article ID - 20800338 [pubmed] ID - S0302-2838(10)00681-0 [pii] ID - 10.1016/j.eururo.2010.07.020 [doi] PP - ppublish PH - 2010/05/03 [received] PH - 2010/07/13 [accepted] LG - English EP - 20100804 DP - 2010 Nov DC - 20110318 EZ - 2010/08/31 06:00 DA - 2011/07/30 06:00 DT - 2010/08/31 06:00 YR - 2010 ED - 20110729 RD - 20110318 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20800338 <398. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20728265 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Stranne J AU - Johansson E AU - Nilsson A AU - Bill-Axelson A AU - Carlsson S AU - Holmberg L AU - Johansson JE AU - Nyberg T AU - Ruutu M AU - Wiklund NP AU - Steineck G FA - Stranne, Johan FA - Johansson, Eva FA - Nilsson, Andreas FA - Bill-Axelson, Anna FA - Carlsson, Stefan FA - Holmberg, Lars FA - Johansson, Jan-Erik FA - Nyberg, Tommy FA - Ruutu, Mirja FA - Wiklund, N Peter FA - Steineck, Gunnar IN - Stranne, Johan. Department of Oncology and Pathology, Division of Clinical Cancer Epidemiology, Karolinska Institute, Stockholm, Sweden. johan.stranne@vgregion.se TI - Inguinal hernia after radical prostatectomy for prostate cancer: results from a randomized setting and a nonrandomized setting. SO - European Urology. 58(5):719-26, 2010 Nov AS - Eur Urol. 58(5):719-26, 2010 Nov NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Aged MH - Controlled Clinical Trials as Topic/sn [Statistics & Numerical Data] MH - *Hernia, Inguinal/ep [Epidemiology] MH - Humans MH - Incidence MH - Male MH - Middle Aged MH - *Postoperative Complications/ep [Epidemiology] MH - *Prostatectomy/ae [Adverse Effects] MH - Prostatectomy/mt [Methods] MH - *Prostatectomy/sn [Statistics & Numerical Data] MH - Prostatic Neoplasms/ep [Epidemiology] MH - *Prostatic Neoplasms/su [Surgery] MH - Randomized Controlled Trials as Topic/sn [Statistics & Numerical Data] MH - Risk Factors MH - *Robotics/sn [Statistics & Numerical Data] MH - Surveys and Questionnaires MH - Watchful Waiting/sn [Statistics & Numerical Data] AB - BACKGROUND: Observational data indicate that retropubic radical prostatectomy (RRP) for prostate cancer (PCa) may induce inguinal hernia (IH) formation. Little is known about the influence of robot-assisted radical prostatectomy (RALP) on IH risk. AB - OBJECTIVE: To compare the incidence of IH after RRP and RALP to that of nonoperated patients with PCa and to a population control. AB - DESIGN, SETTING, AND PARTICIPANTS: We studied two groups. All 376 men included in the Scandinavian Prostate Cancer Group Study Number 4 constitute study group 1. Patients were randomly assigned RRP or watchful waiting (WW). The 1411 consecutive patients who underwent RRP or RALP at Karolinska University Hospital constitute study group 2. Men without PCa, matched for age and residence to each study group, constitute controls. AB - MEASUREMENTS: Postoperative IH incidence was detected through a validated questionnaire. The participation rates were 82.7% and 88.4% for study groups 1 and 2, respectively. AB - RESULTS AND LIMITATIONS: The Kaplan-Meier cumulative occurrence of IH development after 48 mo in study group 1 was 9.3%, 2.4%, and 0.9% for the RRP, the WW, and the control groups, respectively. There were statistically significant differences between the RRP group and the WW and control groups, but not between the last two. In study group 2 the cumulative risk of IH development at 48 mo was 12.2%, 5.8%, and 2.6% for the RRP, the RALP, and the control group, respectively. There were statistically significant differences between the RRP group and the RALP and control groups, but not between the last two. AB - CONCLUSIONS: RRP for PCa leads to an increased risk of IH development. RALP may lower the risk as compared to open surgery. AB - Copyright © 2010 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(10)00715-3 DO - https://dx.doi.org/10.1016/j.eururo.2010.08.006 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't ID - 20728265 [pubmed] ID - S0302-2838(10)00715-3 [pii] ID - 10.1016/j.eururo.2010.08.006 [doi] PP - ppublish PH - 2010/06/18 [received] PH - 2010/08/03 [accepted] GI - No: R01 CA108746-01A1 Organization: (CA) *NCI NIH HHS* Country: United States LG - English EP - 20100811 DP - 2010 Nov DC - 20110318 EZ - 2010/08/24 06:00 DA - 2011/07/30 06:00 DT - 2010/08/24 06:00 YR - 2010 ED - 20110729 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20728265 <399. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21576560 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Alobid I AU - de Pablo J AU - Mullol J AU - Centellas S AU - Parramon G AU - Carrasco J AU - Armario A AU - Bernal-Sprekelsen M FA - Alobid, Isam FA - de Pablo, Juan FA - Mullol, Joaquim FA - Centellas, Silvia FA - Parramon, Gemma FA - Carrasco, Javier FA - Armario, Antonio FA - Bernal-Sprekelsen, Manuel IN - Alobid, Isam. Rhinology Unit and Smell Clinic, Department of Otorhinolaryngology, Universitat de Barcelona, Villarroel 170, Barcelona 08036, Spain. 32874iao@comb.cat TI - Increased cardiovascular and anxiety outcomes but not endocrine biomarkers of stress during performance of endoscopic sinus surgery: a pilot study among novice surgeons. SO - Archives of Otolaryngology -- Head & Neck Surgery. 137(5):487-92, 2011 May AS - Arch Otolaryngol Head Neck Surg. 137(5):487-92, 2011 May NJ - Archives of otolaryngology--head & neck surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 8603209, alq IO - Arch. Otolaryngol. Head Neck Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - *Anxiety/px [Psychology] MH - Biomarkers/bl [Blood] MH - Blood Pressure/ph [Physiology] MH - Endoscopy/ed [Education] MH - *Endoscopy/px [Psychology] MH - Heart Rate/ph [Physiology] MH - Humans MH - Hydrocortisone/bl [Blood] MH - Male MH - Paranasal Sinus Diseases/px [Psychology] MH - *Paranasal Sinus Diseases/su [Surgery] MH - *Physicians/px [Psychology] MH - Pilot Projects MH - Prolactin/bl [Blood] MH - Statistics, Nonparametric MH - *Stress, Psychological/px [Psychology] MH - Surgery, Computer-Assisted MH - Time Factors AB - OBJECTIVE: To compare psychophysiological responses among novice surgeons during performance of endoscopic sinus surgery (ESS). AB - DESIGN: Randomized study. AB - SETTING: Academic institution. AB - PARTICIPANTS: Fifteen novice surgeons. AB - MAIN OUTCOME MEASURES: The psychophysiological effects of performing ESS were assessed among 15 novice surgeons at 30 minutes before (T - 30), at the beginning of (T0), at 15 minutes (T15), and 45 minutes (T45) during, and at 30 minutes after (T + 30) surgery. Participants were randomized to perform ESS with a computer-assisted surgery system, to perform ESS without a computer-assisted surgery system, or to be evaluated on a nonsurgical day (control day). Measured were the State-Trait Anxiety Inventory score, Visual Analog Anxiety Scale score, heart rate, blood pressure, and plasma cortisol and prolactin levels. AB - RESULTS: Anxiety as measured by the State-Trait Anxiety Inventory score was not modified by the experimental conditions. The mean (SEM) Visual Analog Anxiety Scale score increased (P < .05) during ESS at T0 (2.45 [0.32]), T15 (3.46 [0.50]), and T45 (3.17 [0.46]) compared with the control day (1.19 [0.19], 1.32 [0.26], and 1.20 [0.19], respectively). The mean (SEM) systolic blood pressure (in millimeters of mercury) increased (P < .05) during ESS at T0 (127 [2]), T15 (126 [3]), and T45 (125 [2]) compared with the control day (120 [3], 119 [4], and 116 [3], respectively). The mean (SEM) heart rate (in beats per minute) increased during ESS but was significant only at T15 (73 [4]) compared with the control day (64 [3]). The mean (SEM) plasma cortisol level (in micrograms per deciliter) increased 29% above baseline during performance of ESS and reached a maximum peak at T45 (12.6 [1.2]) compared with the control day (9.7 [1.1]), while prolactin levels did not change. The Visual Analog Anxiety Scale score, heart rate, blood pressure, and endocrine biomarkers of stress were not significantly modified during performance of ESS with a computer-assisted surgery system. AB - CONCLUSION: This study demonstrates for the first time that cardiovascular and anxiety changes during performance of ESS are not associated with increased levels of prototypical endocrine stress hormones. RN - 0 (Biomarkers) RN - 9002-62-4 (Prolactin) RN - WI4X0X7BPJ (Hydrocortisone) ES - 1538-361X IL - 0886-4470 DI - 137/5/487 DO - https://dx.doi.org/10.1001/archoto.2011.60 PT - Journal Article PT - Randomized Controlled Trial ID - 21576560 [pubmed] ID - 137/5/487 [pii] ID - 10.1001/archoto.2011.60 [doi] PP - ppublish LG - English DP - 2011 May DC - 20110517 EZ - 2011/05/18 06:00 DA - 2011/07/27 06:00 DT - 2011/05/18 06:00 YR - 2011 ED - 20110726 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21576560 <400. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21413877 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sutherland DE AU - Perez DS AU - Weeks DC FA - Sutherland, Douglas E FA - Perez, Deo S FA - Weeks, D Champ IN - Sutherland, Douglas E. Department of Urology, MultiCare Health System, Tacoma, Washington 98405, USA. desutherland@gmail.com TI - Robot-assisted simple prostatectomy for severe benign prostatic hyperplasia. SO - Journal of Endourology. 25(4):641-4, 2011 Apr AS - J Endourol. 25(4):641-4, 2011 Apr NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Aged MH - Cohort Studies MH - Humans MH - Male MH - *Prostatectomy/mt [Methods] MH - Prostatic Hyperplasia/pp [Physiopathology] MH - *Prostatic Hyperplasia/su [Surgery] MH - *Robotics/mt [Methods] MH - Treatment Outcome AB - PURPOSE: To validate the feasibility of robot-assisted simple retropubic prostatectomy (RSP) for men with severe benign prostatic hyperplasia (>80g). AB - PATIENTS AND METHODS: Institutional Review Board approval was not sought for this series. Men were offered RSP by two surgeons with a combined experience of >350 robot-assisted radical prostatectomies. The RSP replicated previously published robotic and laparoscopic techniques. Postoperative management consisted of continuous bladder irrigation and closed suction pelvic drainage without suprapubic catheterization. AB - RESULTS: A total of nine men were treated. Indications for RSP included urinary retention in three patients, failed medical management in eight patients, and refusal of medical management in one. Average age was 68 years, mean prostate-specific antigen level was 17.4ng/mL, and the average preoperative gland size (height-width-length volume) was 136.5g (range 86-265g). No operative or immediate postoperative complications occurred, and no transfusions were needed. Average blood loss, operative time, and console time were 206mL, 183 minutes, and 147 minutes, respectively. Average pathologic adenoma volume was 112g (range 53-220g). Average hospitalization time and catheterization time were 32 hours and 13 days, respectively. The mean preoperative International Prostate Symptom Score was 17.8 compared with 7.77 at 6 months postoperatively (P=0.0096, 95% CI 2.83 - 17.40), with a mean follow-up time of 9.25 months. The mean Sexual Health Inventory for Men score was 12.7 preoperatively compared with 12.5 postoperatively (P=0.74, 95% confidence interval - 6.66-9.16). Persistent, severe urinary incontinence (4-6 pads per day) occurred in one patient. AB - CONCLUSIONS: RSP is safe and reproducible when performed by experienced robotic surgeons and provides similar benefits to those associated with robot-assisted radical prostatectomy. In our limited experience, hemostasis was markedly decreased when compared with the open technique. Further investigation is necessary before widespread application of RSP. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2010.0528 PT - Clinical Trial PT - Journal Article ID - 21413877 [pubmed] ID - 10.1089/end.2010.0528 [doi] PP - ppublish LG - English EP - 20110317 DP - 2011 Apr DC - 20110408 EZ - 2011/03/19 06:00 DA - 2011/07/22 06:00 DT - 2011/03/19 06:00 YR - 2011 ED - 20110721 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21413877 <401. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21381954 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Weizer AZ AU - Palella GV AU - Montgomery JS AU - Miller DC AU - Hafez KS FA - Weizer, Alon Z FA - Palella, Gaetano V FA - Montgomery, Jeffrey S FA - Miller, David C FA - Hafez, Khaled S IN - Weizer, Alon Z. Division of Urologic Oncology, Department of Urology, University of Michigan , Ann Arbor, Michigan 48109, USA. aweizer@umich.edu TI - Robot-assisted retroperitoneal partial nephrectomy: technique and perioperative results. SO - Journal of Endourology. 25(4):553-7, 2011 Apr AS - J Endourol. 25(4):553-7, 2011 Apr NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Nephrectomy/mt [Methods] MH - Patient Positioning MH - *Perioperative Care MH - *Retroperitoneal Space/su [Surgery] MH - *Robotics/mt [Methods] MH - Time Factors MH - Treatment Outcome AB - Abstract Growing evidence supports the use of nephron-sparing techniques for the management of appropriately selected renal masses up to 7cm. Compared with the surgical standard of open partial nephrectomy, minimally invasive approaches have demonstrated equivalent cancer control with reduced patient morbidity. Robot assistance has the potential to provide patients and physicians greater access to minimally invasive nephron-sparing surgery. We describe a robot-assisted retroperitoneal approach for the management of posterior renal masses. Our early results suggest reduced perioperative morbidity with the ability to manage more complex tumors. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2010.0481 PT - Clinical Trial PT - Journal Article ID - 21381954 [pubmed] ID - 10.1089/end.2010.0481 [doi] PP - ppublish LG - English EP - 20110307 DP - 2011 Apr DC - 20110408 EZ - 2011/03/09 06:00 DA - 2011/07/22 06:00 DT - 2011/03/09 06:00 YR - 2011 ED - 20110721 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21381954 <402. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21126190 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Johnson EK AU - Hedgepeth RC AU - He C AU - Wood DP Jr FA - Johnson, Emilie K FA - Hedgepeth, Ryan C FA - He, Chang FA - Wood, David P Jr IN - Johnson, Emilie K. Department of Urology, University of Michigan, Ann Arbor, Michigan 48109-5330, USA. emiliej@med.umich.edu TI - The impact of anterior urethropexy during robotic prostatectomy on urinary and sexual outcomes. SO - Journal of Endourology. 25(4):615-9, 2011 Apr AS - J Endourol. 25(4):615-9, 2011 Apr NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Humans MH - Male MH - Middle Aged MH - *Prostatectomy/ae [Adverse Effects] MH - Prostatic Neoplasms/pp [Physiopathology] MH - Prostatic Neoplasms/su [Surgery] MH - *Sexual Behavior MH - *Urethra/su [Surgery] MH - *Urination AB - OBJECTIVES: We determined the effect of an anterior urethropexy (AU) stitch on postoperative urinary continence, irritative urinary symptoms, and sexual function after robotic radical prostatectomy (RP). AB - METHODS: Consecutive patients undergoing robotic RP for prostate cancer were prospectively evaluated. The Expanded Prostate Cancer Index Composite (EPIC) questionnaire was administered pre- and postoperatively to all patients. Patients were then grouped by AU status. A linear mixed model was used to compare the rate of recovery in incontinence (UIN), irritative (UIR), and sexual domain scores between the two groups. A t-test was used to compare UIN, UIR, and sexual domain scores at specific time points. AB - RESULTS: A total of 229 patients underwent robotic RP and filled out a preoperative and at least one postoperative EPIC questionnaire. In this population, 87 did have and 142 did not have an AU performed. The mean EPIC-UIN score at 3 months was 68 in the AU group and 58 in the non-AU group (p=0.015). Comparison of all other time points and overall urinary scores revealed no other statistically significant differences after surgery. Sexual domain scores were also improved at 3 months in the AU group (p=0.002). AB - CONCLUSIONS: AU during robotic RP leads to improved urinary continence and sexual functioning at 3 months of follow-up. An earlier return to continence may facilitate an earlier return to sexual activity. AU may offer a short-term quality-of-life advantage for patients undergoing robotic RP. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2010.0413 PT - Clinical Trial PT - Journal Article ID - 21126190 [pubmed] ID - 10.1089/end.2010.0413 [doi] PP - ppublish LG - English EP - 20101202 DP - 2011 Apr DC - 20110408 EZ - 2010/12/04 06:00 DA - 2011/07/22 06:00 DT - 2010/12/04 06:00 YR - 2011 ED - 20110721 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21126190 <403. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21035248 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Di Pierro GB AU - Baumeister P AU - Stucki P AU - Beatrice J AU - Danuser H AU - Mattei A FA - Di Pierro, Giovanni B FA - Baumeister, Philipp FA - Stucki, Patrick FA - Beatrice, Josef FA - Danuser, Hansjorg FA - Mattei, Agostino IN - Di Pierro, Giovanni B. Klinik fur Urologie, Luzerner Kantonsspital, Lucerne, Switzerland. TI - A prospective trial comparing consecutive series of open retropubic and robot-assisted laparoscopic radical prostatectomy in a centre with a limited caseload. CM - Comment in: Eur Urol. 2011 Jan;59(1):7-9; PMID: 21035249 SO - European Urology. 59(1):1-6, 2011 Jan AS - Eur Urol. 59(1):1-6, 2011 Jan NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Aged MH - Clinical Competence MH - Erectile Dysfunction/dt [Drug Therapy] MH - Erectile Dysfunction/et [Etiology] MH - Hospitals MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy MH - Learning Curve MH - Lymph Node Excision MH - Male MH - Middle Aged MH - Phosphodiesterase 5 Inhibitors/tu [Therapeutic Use] MH - Prospective Studies MH - Prostate-Specific Antigen/bl [Blood] MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotics MH - Surgery, Computer-Assisted/ae [Adverse Effects] MH - *Surgery, Computer-Assisted MH - Switzerland MH - Time Factors MH - Treatment Outcome MH - Urinary Incontinence/et [Etiology] MH - Workload AB - BACKGROUND: Robot-assisted radical prostatectomy (RALP) is performed worldwide, even in institutions with limited caseloads. However, although the results of large RALP series are available, oncologic and functional outcomes as well as complications from low-caseload centres are lacking. AB - OBJECTIVE: To compare perioperative, oncologic, and functional outcomes from two consecutive series of patients with localised prostate cancer treated by retropubic radical prostatectomy (RRP) or recently established RALP in our hospital, which has a limited caseload. AB - DESIGN, SETTING, AND PARTICIPANTS: One hundred fifty consecutive patients were enrolled. Their data and outcomes were collected and extensively evaluated. AB - INTERVENTION: Seventy-five consecutive patients underwent RRP, and 75 consecutive patients underwent RALP, including all patients of the learning curve. AB - MEASUREMENTS: Patient baseline characteristics, perioperative and postoperative outcomes, and complications were evaluated. End points were oncologic data (positive margins, prostate-specific antigen [PSA]), perioperative complications, urinary continence, and erectile function at 3- and 12-mo follow-up. AB - RESULTS AND LIMITATIONS: The preoperative parameters from the two groups were comparable. The positive surgical margin (PSM) rates were 32% for RRP and 16% for RALP (p=0.002). For RRP and RALP, the PSA value was <0.2 ng/ml in 91% and 88% of patients 3 mo postoperatively (p=0.708) and in 87% and 89% of patients 12 mo postoperatively (p=0.36), respectively. Continence rates for RRP and RALP were 83% and 95% at 3-mo follow-up (p=0.003) and 80% and 89% after 12-mo follow-up (p=0.092), respectively. Among patients who were potent without phosphodiesterase type 5 inhibitors (PDE5-I) before RRP and RALP, recovery of erectile function with and without PDE5-Is was achieved in 25% (12 of 49 patients) and 68% (25 of 37 patients) 3 mo postoperatively (p=0.009) and in 26% (12 of 47 patients) and 55% (12 of 22 patients) 12 mo postoperatively (p=0.009), respectively. Minimal follow-up for RRP was 12 mo; median follow-up for the RALP group was 12 mo (range: 3-12). According to the modified Clavien system, major complication rates for RRP and RALP were 28% and 7% (p=0.025), respectively; minor complication rates were 24% and 35% (p=0.744), respectively. AB - CONCLUSIONS: Despite a limited caseload and including the learning curve, RALP offers slightly better results than RRP in terms of PSM, major complications, urinary continence, and erectile function. AB - Copyright © 2010 European Association of Urology. Published by Elsevier B.V. All rights reserved. RN - 0 (Phosphodiesterase 5 Inhibitors) RN - EC 3-4-21-77 (Prostate-Specific Antigen) ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(10)00964-4 DO - https://dx.doi.org/10.1016/j.eururo.2010.10.026 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 21035248 [pubmed] ID - S0302-2838(10)00964-4 [pii] ID - 10.1016/j.eururo.2010.10.026 [doi] PP - ppublish PH - 2010/08/28 [received] PH - 2010/10/11 [accepted] LG - English EP - 20101021 DP - 2011 Jan DC - 20110318 EZ - 2010/11/02 06:00 DA - 2011/07/19 06:00 DT - 2010/11/03 06:00 YR - 2011 ED - 20110718 RD - 20110318 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21035248 <404. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20708331 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Williams SB AU - Alemozaffar M AU - Lei Y AU - Hevelone N AU - Lipsitz SR AU - Plaster BA AU - Hu JC FA - Williams, Stephen B FA - Alemozaffar, Mehrdad FA - Lei, Yin FA - Hevelone, Nathanael FA - Lipsitz, Stuart R FA - Plaster, Blakely A FA - Hu, Jim C IN - Williams, Stephen B. Division of Urologic Surgery, Brigham and Women's Hospital, Boston, MA, USA. TI - Randomized controlled trial of barbed polyglyconate versus polyglactin suture for robot-assisted laparoscopic prostatectomy anastomosis: technique and outcomes. SO - European Urology. 58(6):875-81, 2010 Dec AS - Eur Urol. 58(6):875-81, 2010 Dec NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Aged MH - Anastomosis, Surgical MH - Boston MH - Chi-Square Distribution MH - Cost-Benefit Analysis MH - Hospital Costs MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/ec [Economics] MH - *Laparoscopy/is [Instrumentation] MH - Male MH - Middle Aged MH - Polyglactin 910/ae [Adverse Effects] MH - Polyglactin 910/ec [Economics] MH - *Polyglactin 910 MH - Polymers/ae [Adverse Effects] MH - Polymers/ec [Economics] MH - *Polymers MH - Prospective Studies MH - Prostatectomy/ae [Adverse Effects] MH - Prostatectomy/ec [Economics] MH - *Prostatectomy/is [Instrumentation] MH - Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/ec [Economics] MH - *Prostatic Neoplasms/su [Surgery] MH - Robotics/ec [Economics] MH - *Robotics/is [Instrumentation] MH - Surgery, Computer-Assisted/ae [Adverse Effects] MH - Surgery, Computer-Assisted/ec [Economics] MH - *Surgery, Computer-Assisted/is [Instrumentation] MH - Suture Techniques/ae [Adverse Effects] MH - Suture Techniques/ec [Economics] MH - *Suture Techniques/is [Instrumentation] MH - Sutures/ae [Adverse Effects] MH - Sutures/ec [Economics] MH - *Sutures MH - Time Factors MH - Treatment Outcome MH - Urinary Catheterization MH - Wound Healing AB - BACKGROUND: Transperitoneal robot-assisted laparoscopic prostatectomy (RALP) urethrovesical anastomosis is a critical step. Although the prevalence of urine leaks ranges from 4.5% to 7.5% at high-volume RALP centers, urine leaks prolong catheterization and may lead to ileus, peritonitis, and require intervention. Barbed polyglyconate sutures maintain running suture line tension and may be advantageous in RALP anastomosis for reducing this complication. AB - OBJECTIVE: To compare barbed polyglyconate and polyglactin 910 (Vicryl, Ethicon, Somerville, NJ, USA) running sutures for RALP anastomosis. AB - DESIGN, SETTING, AND PARTICIPANTS: This was a prospective, randomized, controlled, single-surgeon study comparing RALP anastomosis using either barbed polyglyconate (n = 45) or polyglactin 910 (n = 36) sutures. AB - SURGICAL PROCEDURE: RALP anastomosis using either barbed polyglyconate or polyglactin 910 sutures was studied. AB - MEASUREMENTS: Operative time, cost differential, perioperative complications, and cystogram contrast extravasation by anastomosis suture type were measured. AB - RESULTS AND LIMITATIONS: Although baseline characteristics and overall operative times were similar, barbed polyglyconate sutures were associated with shorter mean anastomosis times of 9.7 min versus 9.8 min (p = 0.014). In addition, anastomosis with barbed polyglyconate rather than polyglactin 910 sutures was associated with more frequent cystogram extravasation 8 d postoperatively (20.0% vs 2.8%; p = 0.019), longer mean catheterization times (11.1 d vs 8.3 d; p = 0.048), and greater suture costs per case ($51.52 vs $8.44; p < 0.001). After 8 of 29 (27.6%) barbed polyglyconate anastomosis sites demonstrated postoperative day 8 cystogram extravasation, we modified our technique to avoid overtightening, reducing cystogram extravasation to 1 (6.3%) of 16 subsequent barbed polyglyconate anastomosis sites. Potential limitations include small sample size and the single-surgeon study design. AB - CONCLUSIONS: Compared to traditional sutures, barbed polyglyconate is more costly and requires technical modification to avoid overtightening, delayed healing, and longer catheterization time following RALP. AB - Copyright © 2010 European Association of Urology. Published by Elsevier B.V. All rights reserved. RN - 0 (Polymers) RN - 34346-01-5 (Polyglactin 910) RN - 75734-93-9 (polyglyconate) ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(10)00682-2 DO - https://dx.doi.org/10.1016/j.eururo.2010.07.021 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Video-Audio Media ID - 20708331 [pubmed] ID - S0302-2838(10)00682-2 [pii] ID - 10.1016/j.eururo.2010.07.021 [doi] PP - ppublish PH - 2010/06/08 [received] PH - 2010/07/13 [accepted] LG - English EP - 20100802 DP - 2010 Dec DC - 20110318 EZ - 2010/08/17 06:00 DA - 2011/07/08 06:00 DT - 2010/08/17 06:00 YR - 2010 ED - 20110707 RD - 20110318 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20708331 <405. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20950844 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Choi H AU - Kang SH AU - Yoon DK AU - Kang SG AU - Ko HY AU - Moon du G AU - Park JY AU - Joo KJ AU - Cheon J FA - Choi, Hoon FA - Kang, Seok Ho FA - Yoon, Duck Ki FA - Kang, Sung Gu FA - Ko, Hwii Young FA - Moon, Du Geon FA - Park, Jae Young FA - Joo, Kwan Joong FA - Cheon, Jun IN - Choi, Hoon. Department of Urology, Korea University School of Medicine, Seoul, Korea. TI - Chewing gum has a stimulatory effect on bowel motility in patients after open or robotic radical cystectomy for bladder cancer: a prospective randomized comparative study. SO - Urology. 77(4):884-90, 2011 Apr AS - Urology. 77(4):884-90, 2011 Apr NJ - Urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Aged MH - *Chewing Gum MH - *Cystectomy/mt [Methods] MH - Female MH - Flatulence MH - *Gastrointestinal Motility MH - Humans MH - Ileus/pc [Prevention & Control] MH - Laparoscopy MH - Male MH - Middle Aged MH - Postoperative Complications/pc [Prevention & Control] MH - Postoperative Period MH - Prospective Studies MH - *Recovery of Function MH - Robotics MH - *Urinary Bladder Neoplasms/su [Surgery] AB - OBJECTIVES: To determine whether chewing gum during the postoperative period facilitates the recovery of bowel function and has different efficacy according to operative method used in patients with radical cystectomy. AB - METHODS: From July 2007 to September 2009, we randomized open radical cystectomy (ORC) patients into Group AI (ORC without gum chewing) and Group AII (ORC with gum chewing). Robot-assisted radical cystectomy (RARC) patients were randomized into Group BI (RARC without gum chewing) and Group BII (RARC with gum chewing). AB - RESULTS: A total of 32 ORC (17 Group AI and 15 Group AII) and 28 RARC (13 Group BI and 15 Group BII) patients were completed. The patient's perioperative data between the control (AI + BI) and chewing gum (AII + BII) group showed no differences. The median time to flatus and to bowel movement were significantly reduced in chewing gum group compared with the control patients: 57.1 vs. 69.5 hours 76.7 vs. 93.3 hours. In the ORC patients, decrease in time to flatus and bowel movement were observed in gum chewing (AII) group than control (AI) group: 64.3 vs. 80.3 hours 83.8 vs. 104.2 hours. In RARC patients, decrease in time to flatus and bowel movement were found in gum chewing (BII) group than control (BI) group: 48.8 vs. 60.3 hours 69.1 vs. 84.6 hours. No adverse effects were observed with chewing gum. AB - CONCLUSIONS: Chewing gum had stimulatory effects on bowel motility after cystectomy and urinary diversion. Chewing gum was safe and could be used for postoperative ileus regardless of the operative method (ORC or RARC). AB - Copyright © 2011 Elsevier Inc. All rights reserved. RN - 0 (Chewing Gum) ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(10)00897-6 DO - https://dx.doi.org/10.1016/j.urology.2010.06.042 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 20950844 [pubmed] ID - S0090-4295(10)00897-6 [pii] ID - 10.1016/j.urology.2010.06.042 [doi] PP - ppublish PH - 2009/12/23 [received] PH - 2010/05/22 [revised] PH - 2010/06/22 [accepted] LG - English EP - 20101015 DP - 2011 Apr DC - 20110411 EZ - 2010/10/19 06:00 DA - 2011/07/05 06:00 DT - 2010/10/19 06:00 YR - 2011 ED - 20110704 RD - 20110411 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=20950844 <406. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21401397 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Brien JC AU - Barone B AU - Fabrizio M AU - Given R FA - Brien, James C FA - Barone, Bethany FA - Fabrizio, Michael FA - Given, Robert IN - Brien, James C. Department of Urology, Eastern Virginia Medical School, Norfolk, Virginia 23507, USA. brien.james@gmail.com TI - Posterior reconstruction before vesicourethral anastomosis in patients undergoing robot-assisted laparoscopic prostatectomy leads to earlier return to baseline continence. SO - Journal of Endourology. 25(3):441-5, 2011 Mar AS - J Endourol. 25(3):441-5, 2011 Mar NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Anastomosis, Surgical MH - Humans MH - *Laparoscopy MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Prostate/su [Surgery] MH - *Prostatectomy/mt [Methods] MH - Quality of Life MH - *Reconstructive Surgical Procedures/mt [Methods] MH - *Recovery of Function/ph [Physiology] MH - *Robotics/mt [Methods] MH - Treatment Outcome MH - Urethra/pp [Physiopathology] MH - *Urethra/su [Surgery] MH - Urinary Bladder/pp [Physiopathology] MH - *Urinary Bladder/su [Surgery] AB - INTRODUCTION: Reapproximation of Denonvilliers' fascia adjacent to bladder neck to the rectourethralis, or posterior reconstruction (PR), has been suggested to improve continence in postprostatectomy patients. We examined the impact of the PR on postoperative urinary and other quality-of-life (QoL) outcomes in patients undergoing robot-assisted laparoscopic prostatectomy (RALP). AB - METHODS: We identified 89 patients who underwent RALP for prostate cancer between 2006 and 2009 by a single surgeon (R.G.), consented to participate in our prospective QoL study, which collects RAND-UCLA QoL and AUA symptom scores for all patients undergoing treatment for prostate cancer, and completed a baseline and a 3- or 6-month questionnaire. Of these, 31 patients had PR before vesicourethral anastomosis. We compared return to baseline function percentage at 3 and 6 months by PR group. Differences found in univariate analysis were further investigated using multiple linear regression models adjusting for demographics, clinical variables, and nerve-sparing status. AB - RESULTS: While most patients had both 3- and 6-month follow-up (n = 74, 83%), sample size at 3 months was n = 86 and at 6 months was n = 77. Groups were comparable by preoperative characteristics, pathologic stage, nerve-sparing status, and baseline QoL/AUA symptom scores. At 3-months, there was a statistically significant improvement comparing PR to non-PR groups in return to baseline score for urinary bother (72% vs. 53%; p = 0.008) and urinary function (64% vs. 50%; p = 0.05), as well as change in absolute AUA symptom score (+0.2 vs. +3.8; p = 0.005). Differences in urinary bother (+20%; 95% confidence interval 5%, 34%) and AUA symptom score (-2.8; 95% confidence interval, -5.4, -0.2) persisted after multivariate adjustment. Groups had similar scores for all parameters by 6 months postprostatectomy. AB - CONCLUSIONS: PR in patients undergoing RALP has a significant impact on early return to baseline parameters relating to urinary bother, urinary function, and AUA symptom score. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2010.0251 PT - Clinical Trial PT - Journal Article ID - 21401397 [pubmed] ID - 10.1089/end.2010.0251 [doi] PP - ppublish LG - English DP - 2011 Mar DC - 20110315 EZ - 2011/03/16 06:00 DA - 2011/07/02 06:00 DT - 2011/03/16 06:00 YR - 2011 ED - 20110701 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21401397 <407. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21351886 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sammon J AU - Petros F AU - Sukumar S AU - Bhandari A AU - Kaul S AU - Menon M AU - Rogers C FA - Sammon, Jesse FA - Petros, Firas FA - Sukumar, Shyam FA - Bhandari, Akshay FA - Kaul, Sanjeev FA - Menon, Mani FA - Rogers, Craig IN - Sammon, Jesse. Vattikuti Urology Institute, Henry Ford Hospital, Detroit, Michigan 48202, USA. jsammon1@hfhs.org TI - Barbed suture for renorrhaphy during robot-assisted partial nephrectomy. SO - Journal of Endourology. 25(3):529-33, 2011 Mar AS - J Endourol. 25(3):529-33, 2011 Mar NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Humans MH - *Kidney/su [Surgery] MH - Middle Aged MH - *Nephrectomy/mt [Methods] MH - *Robotics/mt [Methods] MH - *Suture Techniques MH - *Sutures MH - Treatment Outcome AB - BACKGROUND AND PURPOSE: Robot-assisted partial nephrectomy (RAPN) is an emerging technique for minimally invasive nephron-sparing surgery that may facilitate the technical challenges of sutured renorrhaphy. Barbed suture allows for knotless wound closure and improves suturing efficiency. We present the first clinical study of barbed suture for renorrhaphy during RAPN in human patients and compare perioperative outcomes to RAPN with polyglactin suture. AB - PATIENTS AND METHODS: Thirty consecutive patients underwent RAPN by a single surgeon; 15 using polyglactin suture for renorrhaphy followed by 15 using the V-Loc 180 wound closure device. Renorrhaphy was performed in two layers, with a continuous running closure of deep vessels and the collecting system, followed by a running closure of the renal capsule, using the sliding Hem-o-lok clip technique. Operative characteristics and complications were compared between groups. AB - RESULTS: Renorrhaphy was successfully completed in all 30 consecutive RAPN procedures. V-Loc and conventional groups were equivalent in demographic and tumor characteristics. Mean operative and console time were equivalent; warm ischemia time was significantly shorter in the V-Loc group (18.5 vs 24.7 min, P = 0.008). There were no instances of suture slippage or tearing in the barbed suture group. The barbs held the sliding clip renorrhaphy intact without the need for redundant clips to prevent backsliding. AB - CONCLUSION: Use of barbed suture simplifies the renorrhaphy technique during RAPN and improves efficiency, allowing for reduced warm ischemia times. We demonstrate feasibility and safety of this suture technique in human patients undergoing minimally invasive partial nephrectomy. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2010.0455 PT - Clinical Trial PT - Journal Article ID - 21351886 [pubmed] ID - 10.1089/end.2010.0455 [doi] PP - ppublish LG - English EP - 20110225 DP - 2011 Mar DC - 20110315 EZ - 2011/03/01 06:00 DA - 2011/07/02 06:00 DT - 2011/03/01 06:00 YR - 2011 ED - 20110701 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21351886 <408. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20817638 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Siu KC AU - Suh IH AU - Mukherjee M AU - Oleynikov D AU - Stergiou N FA - Siu, Ka-Chun FA - Suh, Irene H FA - Mukherjee, Mukul FA - Oleynikov, Dmitry FA - Stergiou, Nick IN - Siu, Ka-Chun. University of Nebraska Medical Center, Omaha, NE 68198-5110, USA. kcsiu@unmc.edu TI - The effect of music on robot-assisted laparoscopic surgical performance. SO - Surgical Innovation. 17(4):306-11, 2010 Dec AS - Surg Innov. 17(4):306-11, 2010 Dec NJ - Surgical innovation PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101233809 IO - Surg Innov SB - Index Medicus CP - United States MH - Adult MH - Biomechanical Phenomena MH - *Clinical Competence MH - Electromyography MH - Humans MH - *Laparoscopy MH - Models, Anatomic MH - *Music MH - *Robotics MH - *Surgical Mesh MH - *Suture Techniques MH - Task Performance and Analysis MH - Young Adult AB - Music is often played in the operating room to increase the surgeon's concentration and to mask noise. It could have a beneficial effect on surgical performance. Ten participants with limited experience with the da Vinci robotic surgical system were recruited to perform two surgical tasks: suture tying and mesh alignment when classical, jazz, hip-hop, and Jamaican music were presented. Kinematics of the instrument tips of the surgical robot and surface electromyography of the subjects were recorded. Results revealed that a significant music effect was found for both tasks with decreased time to task completion (P = .005) and total travel distance (P = .021) as well as reduced muscle activations ( P = .016) and increased median muscle frequency (P = .034). Subjects improved their performance significantly when they listened to either hip-hop or Jamaican music. In conclusion, music with high rhythmicity has a beneficial effect on robotic surgical performance. Musical environment may benefit surgical training and make acquisition of surgical skills more efficient. ES - 1553-3514 IL - 1553-3506 DI - 1553350610381087 DO - https://dx.doi.org/10.1177/1553350610381087 PT - Controlled Clinical Trial PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't ID - 20817638 [pubmed] ID - 1553350610381087 [pii] ID - 10.1177/1553350610381087 [doi] PP - ppublish GI - No: K25HD047194 Organization: (HD) *NICHD NIH HHS* Country: United States LG - English EP - 20100903 DP - 2010 Dec DC - 20101229 EZ - 2010/09/07 06:00 DA - 2011/06/29 06:00 DT - 2010/09/08 06:00 YR - 2010 ED - 20110628 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20817638 <409. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21088594 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Campos JH AU - Hallam EA AU - Ueda K FA - Campos, Javier H FA - Hallam, Ezra A FA - Ueda, Kenichi IN - Campos, Javier H. Department of Anesthesia, University of Iowa, Iowa City, Iowa 52242-1079, USA. javier-campos@uiowa.edu TI - Training in placement of the left-sided double-lumen tube among non-thoracic anaesthesiologists: intubation model simulator versus computer-based digital video disc, a randomised controlled trial. SO - European Journal of Anaesthesiology. 28(3):169-74, 2011 Mar AS - Eur J Anaesthesiol. 28(3):169-74, 2011 Mar NJ - European journal of anaesthesiology PI - Journal available in: Print PI - Citation processed from: Internet JC - ems, 8411711 IO - Eur J Anaesthesiol SB - Index Medicus CP - England MH - Adult MH - Aged MH - Aged, 80 and over MH - *Anesthesiology/ed [Education] MH - *Computer-Assisted Instruction/mt [Methods] MH - Esophagus/su [Surgery] MH - Female MH - Follow-Up Studies MH - Humans MH - *Intubation, Intratracheal/mt [Methods] MH - Male MH - Middle Aged MH - Respiration, Artificial/mt [Methods] MH - Teaching/mt [Methods] MH - *Thoracic Surgical Procedures/mt [Methods] MH - User-Computer Interface MH - Videodisc Recording MH - Young Adult AB - OBJECTIVES: To compare the effectiveness of training with an airway model simulator versus digital video disc (DVD)-based instruction in placement of double-lumen endotracheal (DLT) tubes by anaesthesiologists with limited thoracic experience. AB - DESIGN: Single academic centre parallel randomised controlled trial with computer-generated random allocation. AB - PARTICIPANTS: Sixty patients undergoing elective thoracic or oesophageal surgeries requiring one-lung ventilation. Twenty-seven non-thoracic anaesthesiologists were randomised to place a DLT. AB - INTERVENTION: DLT placement instruction by an interactive airway simulator or computer-based DVD training. The main outcome measure was successful DLT placement. AB - RESULTS: Twenty-seven anaesthesiologists were randomised to one of the two intervention groups. Sixty consecutive patients were assigned to a randomised anaesthesiologist (n = 30 in each group). Participants failed to correctly place or position the DLT tubes in 14 of 60 patients (failure rate of 23%). There was no difference in the probability of satisfactory placement or time for positioning of the DLT between the training groups; 80.5% (95% confidence interval 58.2-96.2%) of tubes were successfully placed following intubation model simulator training versus 73.6% (95% confidence interval 49.8-88.5%) in the DVD group (P = 0.378). AB - CONCLUSION: Both teaching methods had similar outcomes for placement of DLTs by anaesthesiologists with limited thoracic anaesthesia experience. Both groups performed better than individuals in our prior study. Therefore, these methods should be considered when training anaesthesiologists to successfully place DLTs. ES - 1365-2346 IL - 0265-0215 DO - https://dx.doi.org/10.1097/EJA.0b013e328340c332 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 21088594 [pubmed] ID - 10.1097/EJA.0b013e328340c332 [doi] PP - ppublish LG - English DP - 2011 Mar DC - 20110218 EZ - 2010/11/20 06:00 DA - 2011/06/11 06:00 DT - 2010/11/20 06:00 YR - 2011 ED - 20110610 RD - 20110218 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21088594 <410. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21350242 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Dapp U AU - Anders JA AU - von Renteln-Kruse W AU - Minder CE AU - Meier-Baumgartner HP AU - Swift CG AU - Gillmann G AU - Egger M AU - Beck JC AU - Stuck AE AU - PRO-AGE Study Group FA - Dapp, Ulrike FA - Anders, Jennifer A M FA - von Renteln-Kruse, Wolfgang FA - Minder, Christoph E FA - Meier-Baumgartner, Hans Peter FA - Swift, Cameron G FA - Gillmann, Gerhard FA - Egger, Matthias FA - Beck, John C FA - Stuck, Andreas E FA - PRO-AGE Study Group IN - Dapp, Ulrike. Albertinen-Haus Geriatrics Center, Scientific Department at the University of Hamburg, Germany. IR - Lubke N IR - Laub S IR - Gihsa K IR - Golgert S IR - Iliffe S IR - Kharicha K IR - Harari D IR - Born S IR - Moser A IR - Munzer T IR - Wagner J IR - Goetz SM IR - Hansen G IR - Weritz-Hanf P IR - Herz I IR - Herz W IR - Satrapa-Schill A TI - A randomized trial of effects of health risk appraisal combined with group sessions or home visits on preventive behaviors in older adults. SO - Journals of Gerontology Series A-Biological Sciences & Medical Sciences. 66(5):591-8, 2011 May AS - J Gerontol A Biol Sci Med Sci. 66(5):591-8, 2011 May NJ - The journals of gerontology. Series A, Biological sciences and medical sciences PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - cba, 9502837 IO - J. Gerontol. A Biol. Sci. Med. Sci. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Germany MH - *Group Processes MH - Health Behavior MH - *Health Promotion/mt [Methods] MH - *Health Services for the Aged MH - *Health Status Indicators MH - *House Calls MH - Humans MH - Patient Care Team MH - Preventive Health Services MH - Reinforcement (Psychology) AB - BACKGROUND: To explore effects of a health risk appraisal for older people (HRA-O) program with reinforcement, we conducted a randomized controlled trial in 21 general practices in Hamburg, Germany. AB - METHODS: Overall, 2,580 older patients of 14 general practitioners trained in reinforcing recommendations related to HRA-O-identified risk factors were randomized into intervention (n = 878) and control (n = 1,702) groups. Patients (n = 746) of seven additional matched general practitioners who did not receive this training served as a comparison group. Patients allocated to the intervention group, and their general practitioners, received computer-tailored written recommendations, and patients were offered the choice between interdisciplinary group sessions (geriatrician, physiotherapist, social worker, and nutritionist) and home visits (nurse). AB - RESULTS: Among the intervention group, 580 (66%) persons made use of personal reinforcement (group sessions: 503 [87%], home visits: 77 [13%]). At 1-year follow-up, persons in the intervention group had higher use of preventive services (eg, influenza vaccinations, adjusted odds ratio 1.7; 95% confidence interval 1.4-2.1) and more favorable health behavior (eg, high fruit/fiber intake, odds ratio 2.0; 95% confidence interval 1.6-2.6), as compared with controls. Comparisons between intervention and comparison group data revealed similar effects, suggesting that physician training alone had no effect. Subgroup analyses indicated favorable effects for HRA-O with personal reinforcement, but not for HRA-O without reinforcement. AB - CONCLUSIONS: HRA-O combined with physician training and personal reinforcement had favorable effects on preventive care use and health behavior. ES - 1758-535X IL - 1079-5006 DI - glr021 DO - https://dx.doi.org/10.1093/gerona/glr021 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 21350242 [pubmed] ID - glr021 [pii] ID - 10.1093/gerona/glr021 [doi] PP - ppublish LG - English EP - 20110224 DP - 2011 May DC - 20110413 EZ - 2011/02/26 06:00 DA - 2011/06/10 06:00 DT - 2011/02/26 06:00 YR - 2011 ED - 20110609 RD - 20110722 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21350242 <411. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20092954 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bonevski B AU - Campbell E AU - Sanson-Fisher RW FA - Bonevski, B FA - Campbell, E FA - Sanson-Fisher, R W IN - Bonevski, B. Centre for Health Research and Psycho-oncology, Cancer Council NSW and The University of Newcastle, Callaghan, NSW 2308, Australia. TI - The validity and reliability of an interactive computer tobacco and alcohol use survey in general practice. SO - Addictive Behaviors. 35(5):492-8, 2010 May AS - Addict Behav. 35(5):492-8, 2010 May NJ - Addictive behaviors PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 2gw, 7603486 IO - Addict Behav SB - Index Medicus CP - England MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - *Alcohol Drinking/ep [Epidemiology] MH - Alcohol Drinking/ur [Urine] MH - Breath Tests MH - Carbon Monoxide/an [Analysis] MH - Cross-Over Studies MH - Ethanol/ur [Urine] MH - Female MH - General Practice MH - Health Surveys/mt [Methods] MH - *Health Surveys/st [Standards] MH - Humans MH - Male MH - Middle Aged MH - New South Wales/ep [Epidemiology] MH - Reproducibility of Results MH - Self Report/st [Standards] MH - Sensitivity and Specificity MH - *Smoking/ep [Epidemiology] MH - *Software/st [Standards] MH - Young Adult AB - BACKGROUND: Uncertainty regarding the accuracy of the computer as a data collection or patient screening tool persists. Previous research evaluating the validity of computer health surveys have tended to compare those responses to that of paper survey or clinical interview (as the gold standard). This approach is limited as it assumes that the paper version of the self-report survey is valid and an appropriate gold standard. AB - OBJECTIVES: First, to compare the accuracy of computer and paper methods of assessing self-reported smoking and alcohol use in general practice with biochemical measures as gold standard. Second, to compare the test re-test reliability of computer administration, paper administration and mixed methods of assessing self-reported smoking status and alcohol use in general practice. AB - METHODS: A randomised cross-over design was used. Consenting patients were randomly assigned to one of four groups; Group 1. C-C : completing a computer survey at the time of that consultation (Time 1) and a computer survey 4-7 days later (Time 2); Group 2. C-P: completing a computer survey at Time 1 and a paper survey at Time 2; Group 3. P-C: completing a paper survey at Time 1 and a computer survey at Time 2; and Group 4. P-P: completing a paper survey at Time 1 and 2. At Time 1 all participants also completed biochemical measures to validate self-reported smoking status (expired air carbon monoxide breath test) and alcohol consumption (ethyl alcohol urine assay). AB - RESULTS: Of the 618 who were eligible, 575 (93%) consented to completing the Time 1 surveys. Of these, 71% (N=411) completed Time 2 surveys. Compared to CO, the computer smoking self-report survey demonstrated 91% sensitivity, 94% specificity, 75% positive predictive value (PPV) and 98% negative predictive value (NPV). The equivalent paper survey demonstrated 86% sensitivity, 95% specificity, 80% PPV, and 96% NPV. Compared to urine assay, the computer alcohol use self-report survey demonstrated 92% sensitivity, 50% specificity, 10% PPV and 99% NPV. The equivalent paper survey demonstrated 75% sensitivity, 57% specificity, 6% PPV, and 98% NPV. Level of agreement of smoking self-reports at Time 1 and Time 2 revealed kappa coefficients ranging from 0.95 to 0.98 in each group and hazardous alcohol use self-reports at Time 1 and Time 2 revealed kappa coefficients ranging from 0.90 to 0.96 in each group. AB - CONCLUSION: The collection of self-reported health risk information is equally accurate and reliable using computer interface in the general practice setting as traditional paper survey. Computer survey appears highly reliable and accurate for the measurement of smoking status. Further research is needed to confirm the adequacy of the quantity/frequency measure in detecting those who drink alcohol. Interactive computer administered health surveys offer a number of advantages to researchers and clinicians and further research is warranted. AB - Copyright (c) 2010 Elsevier Ltd. All rights reserved. RN - 3K9958V90M (Ethanol) RN - 7U1EE4V452 (Carbon Monoxide) ES - 1873-6327 IL - 0306-4603 DI - S0306-4603(09)00357-8 DO - https://dx.doi.org/10.1016/j.addbeh.2009.12.030 PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 20092954 [pubmed] ID - S0306-4603(09)00357-8 [pii] ID - 10.1016/j.addbeh.2009.12.030 [doi] PP - ppublish PH - 2009/07/01 [received] PH - 2009/11/18 [revised] PH - 2009/12/21 [accepted] LG - English EP - 20100104 DP - 2010 May DC - 20100301 EZ - 2010/01/23 06:00 DA - 2011/06/09 06:00 DT - 2010/01/23 06:00 YR - 2010 ED - 20110608 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20092954 <412. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21358292 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Eltayeb SM AU - Staal JB AU - Khamis AH AU - de Bie RA FA - Eltayeb, Shahla M FA - Staal, J Bart FA - Khamis, Amar H FA - de Bie, Rob A IN - Eltayeb, Shahla M. Department of Epidemiology and Caphri Research School, Maastricht University, Maastricht, The Netherlands. s_eltyeb@hotmail.com TI - Symptoms of neck, shoulder, forearms, and hands: a cohort study among computer office workers in Sudan. SO - Clinical Journal of Pain. 27(3):275-81, 2011 Mar-Apr AS - Clin J Pain. 27(3):275-81, 2011 Mar-Apr NJ - The Clinical journal of pain PI - Journal available in: Print PI - Citation processed from: Internet JC - beg, 8507389 IO - Clin J Pain SB - Index Medicus CP - United States MH - Adult MH - *Arthralgia/ep [Epidemiology] MH - Cohort Studies MH - Comorbidity MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Neck Pain/ep [Epidemiology] MH - *Occupational Diseases/ep [Epidemiology] MH - Prevalence MH - Risk Assessment MH - Risk Factors MH - Sudan/ep [Epidemiology] MH - Upper Extremity MH - *Word Processing/sn [Statistics & Numerical Data] AB - OBJECTIVES: Complaints of the arms, neck, and shoulders in general and computer-related disorders in particular affect many office workers in economically developed countries. However, with the increased use of computer systems in developing countries, the associated musculoskeletal symptoms and risk factors are yet to be investigated. The study investigates the relationship between work-related physical and psychosocial characteristics and symptoms of the arms, neck, and shoulders in an African economically developed worksite. AB - METHODS: A prospective cohort study with 1-year follow-up was conducted. Data were used from 250 computer office workers in Khartoum, Sudan. Data were collected using the Arabic version of the Maastricht Upper Extremity Questionnaire. Prevalence rates for symptoms were calculated and the categories of risk factors being evaluated consisted of physical, psychological, and individual risk factors. Multivariable logistic regression analysis was used to identify risk factors associated with complaints that were expressed as odds ratios (ORs) with 95% confidence intervals (CIs). AB - RESULTS: The 1-year follow-up prevalence rate was 0.63 (95% CI: 0.58-0.70) for neck symptoms, 0.56 (95% CI: 0.45-0.66) for shoulder symptoms, and 0.46 (95% CI: 0.42-0.59) for symptoms of the forearms/hands. Three main risk factors were significantly associated with the presence of symptoms: (1) time pressure [OR: 1.31 (1.00 to 1.90) P=0.05], (2) task difficulty [OR: 1.85 (1.73 to 1.99) P=0.03], and (3) previous history of symptoms [OR: 4.62 (2.20 to 9.35) P=0.01]. AB - CONCLUSIONS: The targeted office workers in Sudan are reporting symptoms in the neck, shoulders, and forearms. Work-related psychological factors predicted more significantly the presence of symptoms in the targeted population. ES - 1536-5409 IL - 0749-8047 DI - 00002508-201103000-00013 DO - https://dx.doi.org/10.1097/AJP.0b013e3181fe94ef PT - Journal Article ID - 21358292 [pubmed] ID - 10.1097/AJP.0b013e3181fe94ef [doi] ID - 00002508-201103000-00013 [pii] PP - ppublish LG - English DP - 2011 Mar-Apr DC - 20110301 EZ - 2011/03/02 06:00 DA - 2011/06/03 06:00 DT - 2011/03/02 06:00 YR - 2011 ED - 20110602 RD - 20110301 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21358292 <413. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21083366 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Marchetti P AU - Razmaria A AU - Zagaja GP AU - Gundeti MS FA - Marchetti, Pablo FA - Razmaria, Aria FA - Zagaja, Greg P FA - Gundeti, Mohan S IN - Marchetti, Pablo. Pediatric Urology Section of Urology, Department of Surgery, Comer Children's Hospital, The University of Chicago Medical Center and Pritzker School of Medicine, Chicago, Illinois, USA. pemarchetti@yahoo.com TI - Management of the ventriculo-peritoneal shunt in pediatric patients during robot-assisted laparoscopic urologic procedures. SO - Journal of Endourology. 25(2):225-9, 2011 Feb AS - J Endourol. 25(2):225-9, 2011 Feb NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adolescent MH - Child MH - Female MH - Humans MH - Intraoperative Care MH - *Laparoscopy MH - Male MH - *Robotics/mt [Methods] MH - *Urologic Surgical Procedures/mt [Methods] MH - *Ventriculoperitoneal Shunt/mt [Methods] AB - INTRODUCTION: Infection or malfunction of ventriculo-peritoneal (VP) shunts is a severe complication during laparoscopic surgery involving the gastrointestinal or urinary tract. It has been recently suggested to externalize the shunt or convert into a ventriculo-atrial shunt to prevent this complication with laparoscopic approach. Herein, we present a novel technique for management of the VP shunt during robot-assisted laparoscopic (RAL) urologic procedures. AB - MATERIALS AND METHODS: After port placement and diagnostic peritoneoscopy, an Endopouch bag (Ethicon Endo-Surgery) was inserted into the peritoneal cavity and the distal end of the shunt was placed into the pouch. The Endopouch suture was synched around the shunt and the pouch was placed in the subhepatic space during the surgery. The intraperitoneal pressure was maintained at 12 mm Hg during the entire procedure. Metronidazole, gentamicin, and vancomycin were administered as prophylaxis. Following the completion of the surgery and profuse irrigation of the peritoneal cavity, the shunt was repositioned within the peritoneum. We evaluated perioperative shunt-related complications. AB - RESULTS: We used this technique in four patients with VP shunt undergoing RAL cystoplasty and appendicovesicostomy and/or colonic enema channel formation. The average age of the patient at surgery was 10.8 (7-14) years. One patient was converted to open because of failure to progress due to multiple adhesions and the shunt was externalized temporarily. At a mean follow-up of 13 (3-20) months, no shunt-related complications were seen. AB - CONCLUSIONS: In our preliminary experience, the use of an intracorporeal Endopouch bag with controlled pneumoperitoneal pressure to protect the VP shunt may be an effective alternative to prevent complications related to it during RAL urologic surgery involving the gastrointestinal or urinary tract. Further studies will be needed to confirm our results. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2010.0181 PT - Clinical Trial PT - Journal Article ID - 21083366 [pubmed] ID - 10.1089/end.2010.0181 [doi] PP - ppublish LG - English EP - 20101117 DP - 2011 Feb DC - 20110228 EZ - 2010/11/19 06:00 DA - 2011/06/03 06:00 DT - 2010/11/19 06:00 YR - 2011 ED - 20110602 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21083366 <414. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21334025 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sutherland DE AU - Linder B AU - Guzman AM AU - Hong M AU - Frazier HA 2nd AU - Engel JD AU - Bianco FJ Jr FA - Sutherland, Douglas E FA - Linder, Brian FA - Guzman, Anna M FA - Hong, Mark FA - Frazier, Harold A 2nd FA - Engel, Jason D FA - Bianco, Fernando J Jr IN - Sutherland, Douglas E. Department of Urology, George Washington University, Washington, DC, USA. TI - Posterior rhabdosphincter reconstruction during robotic assisted radical prostatectomy: results from a phase II randomized clinical trial. CM - Comment in: J Urol. 2011 Apr;185(4):1186-7; PMID: 21334688 CM - Comment in: Eur Urol. 2011 Jul;60(1):180-1; PMID: 21640696 SO - Journal of Urology. 185(4):1262-7, 2011 Apr AS - J Urol. 185(4):1262-7, 2011 Apr NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Humans MH - Male MH - Middle Aged MH - Prospective Studies MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotics MH - Single-Blind Method MH - Treatment Outcome MH - Urinary Incontinence/et [Etiology] MH - *Urinary Incontinence/pc [Prevention & Control] AB - PURPOSE: Posterior rhabdosphincter reconstruction following radical prostatectomy was designed to improve early urinary continence. We executed a randomized clinical trial to test this conjecture in men undergoing robotic radical prostatectomy. AB - MATERIALS AND METHODS: We conducted a phase II randomized clinical trial intended to detect a 25% difference in 3-month continence outcomes defined by a patient response of 0 or 1 to question 5 of the Expanded Prostate Cancer Index Composite questionnaire urinary domain, comparing standard running vesicourethral anastomosis (controls) to posterior rhabdosphincter reconstruction followed by standard running vesicourethral anastomosis (posterior rhabdosphincter reconstruction treated). Patients had clinically localized prostate cancer and were blinded. Surgeons were notified of computer randomization after prostate excision. Further continence outcomes were assessed by analysis of Expanded Prostate Cancer Index Composite questionnaire questions 1 and 12, International Prostate Symptom Score and 24-hour pad weights. Statistical significance was defined as p <0.05 AB - RESULTS: A total of 94 patients were randomized, 47 to each arm. Preoperative clinical and functional variables were equivalent between study arms. There were no complications associated with either anastomotic technique. Of the 87 evaluable patients 62 (71.3%) met our 3-month continence definition. The null hypothesis was not rejected as 33 (81%) controls and 29 (63%) posterior rhabdosphincter reconstruction treated patients were continent at 3 months (chi-square p = 0.07, Fisher exact p = 0.1). Likewise there was no significant difference between arms in 24-hour pad weights (p = 0.14), International Prostate Symptom Score (p = 0.4), absence of daily leaks (p = 0.4) or perception of urinary function (p = 0.4). AB - CONCLUSIONS: In this randomized clinical trial posterior rhabdosphincter reconstruction offered no advantage for return of early continence after robotic assisted radical prostatectomy. AB - Copyright © 2011 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(10)05196-7 DO - https://dx.doi.org/10.1016/j.juro.2010.11.085 PT - Clinical Trial, Phase II PT - Journal Article PT - Randomized Controlled Trial ID - 21334025 [pubmed] ID - S0022-5347(10)05196-7 [pii] ID - 10.1016/j.juro.2010.11.085 [doi] PP - ppublish PH - 2010/08/15 [received] LG - English EP - 20110222 DP - 2011 Apr DC - 20110322 EZ - 2011/02/22 06:00 DA - 2011/05/27 06:00 DT - 2011/02/22 06:00 YR - 2011 ED - 20110526 RD - 20110725 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21334025 <415. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20346703 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Song JG AU - Lee EH AU - Choi DK AU - Chin JH AU - Choi IC FA - Song, Jun-Gol FA - Lee, Eun Ho FA - Choi, Dae Kee FA - Chin, Ji Hyun FA - Choi, In Cheol IN - Song, Jun-Gol. Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. TI - Differences between arterial and expired pump carbon dioxide during robotic cardiac surgery. SO - Journal of Cardiothoracic & Vascular Anesthesia. 25(1):85-9, 2011 Feb AS - J Cardiothorac Vasc Anesth. 25(1):85-9, 2011 Feb NJ - Journal of cardiothoracic and vascular anesthesia PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - a6i, 9110208 IO - J. Cardiothorac. Vasc. Anesth. SB - Index Medicus CP - United States MH - Aged MH - Body Temperature MH - Capnography MH - *Carbon Dioxide/bl [Blood] MH - *Carbon Dioxide/me [Metabolism] MH - *Cardiac Surgical Procedures/mt [Methods] MH - Coronary Artery Bypass MH - Female MH - Heart Valve Prosthesis Implantation MH - Hemodynamics/ph [Physiology] MH - Humans MH - Hypothermia, Induced MH - Male MH - Middle Aged MH - Mitral Valve/su [Surgery] MH - Oxygenators MH - Rewarming MH - *Robotics AB - OBJECTIVE: To investigate whether expired pump carbon dioxide (PepCO(2)) is an effective arterial carbon dioxide (PaCO(2)) monitor during cardiopulmonary bypass (CPB) in patients undergoing robotic cardiac surgery compared with traditional cardiac surgery. AB - DESIGN: A prospective control study. AB - SETTING: A university, single-institutional setting. AB - PARTICIPANTS: Sixty patients undergoing cardiac surgery. AB - INTERVENTIONS: PepCO(2) was measured using a standard multigas analyzer with the monitoring catheter connected to the exhaust port of the oxygenator. The authors measured PaCO(2) values of the arterial blood provided to the patient and PepCO(2) from the oxygenator exhaust outlet during the cooling, stable hypothermia, and rewarming phases of CPB. AB - MEASUREMENTS AND MAIN RESULTS: There were significant differences between temperature-uncorrected PaCO(2) (PaCO(2)tu) and PepCO(2) measured during the cooling phase; between temperature-corrected PaCO(2) (PaCO(2)tc) and PepCO(2); and between PaCO(2)tu and PepCO(2) measured during the stable hypothermia phase between the 2 groups (p < 0.001 for all). However, there were no significant differences between PaCO(2)tc and PepCO(2) measured during the cooling phase or between PaCO(2)tc and PepCO(2) or PaCO(2)tu and PepCO(2) measured during the rewarming phase between the 2 groups (p = 0.453, p = 0.122, and p = 0.412, respectively). AB - CONCLUSION: These results reveal that PepCO(2) is not suitable for continuous monitoring of PaCO(2) during CPB in patients undergoing robotic cardiac surgery. AB - Copyright © 2011 Elsevier Inc. All rights reserved. RN - 142M471B3J (Carbon Dioxide) ES - 1532-8422 IL - 1053-0770 DI - S1053-0770(10)00010-8 DO - https://dx.doi.org/10.1053/j.jvca.2010.01.006 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 20346703 [pubmed] ID - S1053-0770(10)00010-8 [pii] ID - 10.1053/j.jvca.2010.01.006 [doi] PP - ppublish PH - 2009/09/30 [received] LG - English EP - 20100325 DP - 2011 Feb DC - 20110128 EZ - 2010/03/30 06:00 DA - 2011/05/19 06:00 DT - 2010/03/30 06:00 YR - 2011 ED - 20110518 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=20346703 <416. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21485666 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Pellegrino VA AU - Mudaliar Y AU - Gopalakrishnan M AU - Horton MD AU - Killick CJ AU - Parkin WG AU - Playford HR AU - Raper RF FA - Pellegrino, V A FA - Mudaliar, Y FA - Gopalakrishnan, M FA - Horton, M D FA - Killick, C J FA - Parkin, W G FA - Playford, H R FA - Raper, R F IN - Pellegrino, V A. Intensive Care Units, The Alfred Hospital and Monash Medical Centre, Melbourne, Victoria, Australia. v.pellegrino@alfred.org.au TI - Computer based haemodynamic guidance system is effective and safe in management of postoperative cardiac surgery patients. SO - Anaesthesia & Intensive Care. 39(2):191-201, 2011 Mar AS - Anaesth Intensive Care. 39(2):191-201, 2011 Mar NJ - Anaesthesia and intensive care PI - Journal available in: Print PI - Citation processed from: Print JC - 4m5, 0342017 IO - Anaesth Intensive Care SB - Index Medicus CP - Australia MH - Atrial Fibrillation/ep [Epidemiology] MH - Atrial Fibrillation/et [Etiology] MH - Australia MH - Blood Pressure MH - Cardiac Output MH - Cardiac Surgical Procedures/ae [Adverse Effects] MH - *Cardiac Surgical Procedures/mt [Methods] MH - Catheterization/mt [Methods] MH - Critical Care/mt [Methods] MH - Female MH - *Hemodynamics MH - Hospitals, University MH - Humans MH - Length of Stay MH - Male MH - *Postoperative Care/mt [Methods] MH - Postoperative Care/nu [Nursing] MH - Postoperative Complications/pc [Prevention & Control] MH - Prospective Studies MH - Pulmonary Artery MH - *Therapy, Computer-Assisted/mt [Methods] AB - A circulatory guidance system, Navigator, was evaluated in a prospective, randomised control trial at six Australian university teaching hospitals involving 112 scheduled postoperative cardiac surgical patients with pulmonary artery catheters placed and receiving 1:1 nursing care. The guidance system was used to achieve and maintain physician-designated cardiac output and mean arterial pressure targets and compared these with standard post open-heart surgery care. The primary efficacy endpoint was the standardised unsigned error between the targeted and the actual values for cardiac output and mean arterial pressure, time averaged over the duration of cardiac output monitoring - the average standardised distance. This was 1.71 (SD=0.65) for the guidance group and 1.92 (SD=0.65) in the control group (P=0.202). Rates of postoperative atrial fibrillation, adverse events, intensive care unit and hospital length-of-stay were similar in both groups. There were no device-related adverse events. Guided haemodynamic therapy with the Navigator device was non-inferior to standard intensive care unit therapy. The study was registered with ClinicalTrials.gov Identifier NCT00468247. IS - 0310-057X IL - 0310-057X DI - 20100266 PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 21485666 [pubmed] ID - 20100266 [pii] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT00468247 SL - https://clinicaltrials.gov/search/term=NCT00468247 LG - English DP - 2011 Mar DC - 20110413 EZ - 2011/04/14 06:00 DA - 2011/05/13 06:00 DT - 2011/04/14 06:00 YR - 2011 ED - 20110512 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21485666 <417. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20973908 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Stolzenburg JU AU - Franz T AU - Kallidonis P AU - Minh D AU - Dietel A AU - Hicks J AU - Nicolaus M AU - Al-Aown A AU - Liatsikos E FA - Stolzenburg, Jens-Uwe FA - Franz, Toni FA - Kallidonis, Panagiotis FA - Minh, Do FA - Dietel, Anja FA - Hicks, James FA - Nicolaus, Martin FA - Al-Aown, Abdulrahman FA - Liatsikos, Evangelos IN - Stolzenburg, Jens-Uwe. Department of Urology, University of Leipzig, Leipzig, Germany. TI - Comparison of the FreeHand robotic camera holder with human assistants during endoscopic extraperitoneal radical prostatectomy. SO - BJU International. 107(6):970-4, 2011 Mar AS - BJU Int. 107(6):970-4, 2011 Mar NJ - BJU international PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - dcu, 100886721 IO - BJU Int. SB - Index Medicus CP - England MH - Adult MH - Aged MH - *Endoscopy MH - Humans MH - Male MH - Middle Aged MH - *Prostatectomy/is [Instrumentation] MH - Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotics/is [Instrumentation] MH - Treatment Outcome AB - OBJECTIVE: * To assess, in a prospective randomized study, the efficiency of the FreeHand (Prosurgics Ltd, Bracknell, UK) compared to manual camera control during the performance of endoscopic extraperitoneal radical prostatectomy (EERPE). AB - PATIENTS AND METHODS: * Three surgeons performed 50 EERPE for localized prostate cancer. In group A (n= 25), procedures were performed with manual control of the camera by the assistant, whereas group B (n= 25) patients were treated with the assistance of the FreeHand robotic device. * The EERPE procedure was divided into several steps. * Total operation duration, time for each surgical step, number of camera movements, number of movement errors, number of times the lens was cleaned, blood loss and margin status were compared. AB - RESULTS: * No statistically significant difference was observed in terms of patient age, preoperative prostate-specific antigen level, Gleason score, positive cores and prostate volume. * The average operation duration required for the performance of each step did not differ significantly between the two groups. * Significant differences in favour of the FreeHand camera holder were observed in case of horizontal and zooming camera movement, camera cleaning and camera errors. * Vertical camera movements were performed significantly faster by the human assistant compared to the robotic camera holder. * The average total operation duration was similar for both groups. * Positive surgical margins were detected in one patient in each group (4% of the patients). AB - CONCLUSIONS: * A comparison of the FreeHand robotic camera holder with human camera control during EERPE showed a similar time requirement for the performance of each step of the procedure. * The robotic system provided accurate and fast movements of the camera without compromising the outcome of the procedure. AB - Copyright © 2010 THE AUTHORS. BJU INTERNATIONAL © 2010 BJU INTERNATIONAL. ES - 1464-410X IL - 1464-4096 DO - https://dx.doi.org/10.1111/j.1464-410X.2010.09656.x PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 20973908 [pubmed] ID - 10.1111/j.1464-410X.2010.09656.x [doi] PP - ppublish LG - English EP - 20101025 DP - 2011 Mar DC - 20110311 EZ - 2010/10/27 06:00 DA - 2011/05/04 06:00 DT - 2010/10/27 06:00 YR - 2011 ED - 20110503 RD - 20110311 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=20973908 <418. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21204675 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Naeem N AU - Petros F AU - Sukumar S AU - Patel M AU - Bhandari A AU - Kaul S AU - Menon M AU - Rogers C FA - Naeem, Naveed FA - Petros, Firas FA - Sukumar, Shyam FA - Patel, Manish FA - Bhandari, Akshay FA - Kaul, Sanjeev FA - Menon, Mani FA - Rogers, Craig IN - Naeem, Naveed. Henry Ford Hospital, Vattikuti Urology Institute, Detroit, Michigan 48202, USA. TI - Robot-assisted partial nephrectomy in obese patients. SO - Journal of Endourology. 25(1):101-5, 2011 Jan AS - J Endourol. 25(1):101-5, 2011 Jan NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Female MH - Humans MH - Male MH - Middle Aged MH - Nephrectomy/ae [Adverse Effects] MH - *Nephrectomy/mt [Methods] MH - Obesity/pa [Pathology] MH - *Obesity/su [Surgery] MH - Postoperative Complications/et [Etiology] MH - Preoperative Care MH - *Robotics/mt [Methods] AB - PURPOSE: To report our experience with robot-assisted partial nephrectomy (RAPN) in obese patients compared with a contemporary cohort of nonobese patients. AB - PATIENTS AND METHODS: We defined obesity as a body mass index (BMI) > 30 kg/m(2). From June 2004 to September 2009, 97 patients underwent RAPN at our institution, of whom 49 were obese (group 1) and 48 were nonobese (group 2, BMI <30 kg/m(2)). We compared demographics, operative data, complications, and pathological outcomes between these two groups. AB - RESULTS: The average BMI for the obese group was 36.2 kg/m(2) (range 30.3-49) compared with 25.7 kg/m(2) (range 20.5-29.7) for the nonobese group. Median tumor size was 2.5 versus 2.3 cm for obese and nonobese groups, respectively. Obese patients had a larger median estimated blood loss (150 vs.100 mL, p=0.027) and a trend toward a longer median operative time (265 vs. 242.5 minutes, p=0.085) and median warm ischemia time (26.5 vs. 22.5 minutes, p=0.074), but this did not achieve statistical significance. An intraoperative complication occurred in one patient in each group. The postoperative complication rate was not statistically significant between the two groups (8.3% vs. 4.3%, p=0.377). The median hospital stay was 2 days for both groups. AB - CONCLUSIONS: RAPN is safe and feasible in obese patients. Obese patients had a higher estimated blood loss and a trend toward greater operative time and warm ischemia time, which did not achieve statistical significance. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2010.0272 PT - Clinical Trial PT - Journal Article ID - 21204675 [pubmed] ID - 10.1089/end.2010.0272 [doi] PP - ppublish LG - English EP - 20110104 DP - 2011 Jan DC - 20110120 EZ - 2011/01/06 06:00 DA - 2011/04/28 06:00 DT - 2011/01/06 06:00 YR - 2011 ED - 20110427 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21204675 <419. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21114411 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Engel JD AU - Sutherland DE AU - Williams SB AU - Wagner KR FA - Engel, Jason D FA - Sutherland, Douglas E FA - Williams, Stephen B FA - Wagner, Kristofer R IN - Engel, Jason D. Department of Urology, George Washington University Hospital, Washington, District of Columbia, USA. jengel1@dcurology.net TI - Changes in penile length after robot-assisted laparoscopic radical prostatectomy. SO - Journal of Endourology. 25(1):65-9, 2011 Jan AS - J Endourol. 25(1):65-9, 2011 Jan NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Follow-Up Studies MH - Humans MH - *Laparoscopy/ae [Adverse Effects] MH - Male MH - Middle Aged MH - Organ Size MH - *Penis/ah [Anatomy & Histology] MH - Postoperative Care MH - Preoperative Care MH - *Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - *Robotics/mt [Methods] MH - Time Factors AB - BACKGROUND AND PURPOSE: Radical prostatectomy is commonly performed for the treatment of patients with prostate cancer. Several studies have demonstrated a reduction in penile size after open radical retropubic prostatectomy. The objective of this study is to describe changes in penile length after after robot-assisted laparoscopic radical prostatectomy (RALRP). AB - PATIENTS AND METHODS: We performed a randomized, open label, multicenter study in men with normal erectile function who underwent bilateral nerve-sparing radical prostatectomy. We evaluated changes in measured stretched penile length (SPL), a secondary end point of the study, in a subset of men from a single site who underwent RALRP by one surgeon. They were randomized to either intraurethral alprostadil 125 to 250 mug daily or oral sildenafil citrate 50 mg daily for 9 months. SPL was measured from pubic bone to coronal sulcus using a semirigid ruler before surgery and at 1, 3, 6, 9, 10, and 11 months. AB - RESULTS: A total of 127 patients were enrolled and 94 completed the 11-month follow-up. The mean patient age was 56.5 years. Baseline mean SPL (cm) before surgery was 11.77 and decreased to 11.13 at 1 month (P<0.0001). A trend toward recovery of SPL was seen at 3 and 6 months. Mean SPL was not significantly different from baseline at 9, 10, and 11 months. AB - CONCLUSIONS: This report describes changes in SPL over time after RALRP for prostate cancer. The expected decrease in length was observed shortly after surgery, but, by 9 months, penile length had returned to the preoperative measurement. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2010.0382 PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial ID - 21114411 [pubmed] ID - 10.1089/end.2010.0382 [doi] PP - ppublish LG - English EP - 20101129 DP - 2011 Jan DC - 20110120 EZ - 2010/12/01 06:00 DA - 2011/04/28 06:00 DT - 2010/12/01 06:00 YR - 2011 ED - 20110427 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21114411 <420. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20729152 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Song DY AU - Burdette EC AU - Fiene J AU - Armour E AU - Kronreif G AU - Deguet A AU - Zhang Z AU - Iordachita I AU - Fichtinger G AU - Kazanzides P FA - Song, Danny Y FA - Burdette, Everette C FA - Fiene, Jonathan FA - Armour, Elwood FA - Kronreif, Gernot FA - Deguet, Anton FA - Zhang, Zhe FA - Iordachita, Iulian FA - Fichtinger, Gabor FA - Kazanzides, Peter IN - Song, Danny Y. Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, 401 N. Broadway, Baltimore, MD 21231, USA. Dsong2@jhmi.edu TI - Robotic needle guide for prostate brachytherapy: clinical testing of feasibility and performance. SO - Brachytherapy. 10(1):57-63, 2011 Jan-Feb AS - Brachytherapy. 10(1):57-63, 2011 Jan-Feb NJ - Brachytherapy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101137600 IO - Brachytherapy PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021094 OI - Source: NLM. NIHMS232939 SB - Index Medicus CP - United States MH - *Brachytherapy/is [Instrumentation] MH - Feasibility Studies MH - Humans MH - Male MH - *Needles MH - Pilot Projects MH - Prospective Studies MH - Prostatic Neoplasms/dg [Diagnostic Imaging] MH - *Prostatic Neoplasms/rt [Radiotherapy] MH - Robotics MH - Ultrasonography AB - PURPOSE: Optimization of prostate brachytherapy is constrained by tissue deflection of needles and fixed spacing of template holes. We developed and clinically tested a robotic guide toward the goal of allowing greater freedom of needle placement. AB - METHODS AND MATERIALS: The robot consists of a small tubular needle guide attached to a robotically controlled arm. The apparatus is mounted and calibrated to operate in the same coordinate frame as a standard template. Translation in x and y directions over the perineum +/-40 mm are possible. Needle insertion is performed manually. AB - RESULTS: Five patients were treated in an institutional review board-approved study. Confirmatory measurements of robotic movements for initial 3 patients using infrared tracking showed mean error of 0.489 mm (standard deviation, 0.328 mm). Fine adjustments in needle positioning were possible when tissue deflection was encountered; adjustments were performed in 54 (30.2%) of 179 needles placed, with 36 (20.1%) of 179 adjustments of >2mm. Twenty-seven insertions were intentionally altered to positions between the standard template grid to improve the dosimetric plan or avoid structures such as pubic bone and blood vessels. AB - CONCLUSIONS: Robotic needle positioning provided a means of compensating for needle deflections and the ability to intentionally place needles into areas between the standard template holes. To our knowledge, these results represent the first clinical testing of such a system. Future work will be incorporation of direct control of the robot by the physician, adding software algorithms to help avoid robot collisions with the ultrasound, and testing the angulation capability in the clinical setting. AB - Copyright © 2011 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved. ES - 1873-1449 IL - 1538-4721 DI - S1538-4721(10)00244-8 DO - https://dx.doi.org/10.1016/j.brachy.2010.01.003 PT - Clinical Trial PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, U.S. Gov't, Non-P.H.S. ID - 20729152 [pubmed] ID - S1538-4721(10)00244-8 [pii] ID - 10.1016/j.brachy.2010.01.003 [doi] ID - PMC3021094 [pmc] ID - NIHMS232939 [mid] PP - ppublish PH - 2009/11/30 [received] PH - 2010/01/20 [accepted] GI - No: R44 CA088139-04 Organization: (CA) *NCI NIH HHS* Country: United States No: 2R44 CA099374-02 Organization: (CA) *NCI NIH HHS* Country: United States No: R44 CA099374 Organization: (CA) *NCI NIH HHS* Country: United States No: R44 CA088139 Organization: (CA) *NCI NIH HHS* Country: United States No: 5R44 CA088139-04 Organization: (CA) *NCI NIH HHS* Country: United States No: R44 CA099374-02A1 Organization: (CA) *NCI NIH HHS* Country: United States LG - English EP - 20100821 DP - 2011 Jan-Feb DC - 20110121 EZ - 2010/08/24 06:00 DA - 2011/04/27 06:00 DT - 2010/08/24 06:00 YR - 2011 ED - 20110426 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=20729152 <421. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21175276 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sato T AU - Carvalho G AU - Sato H AU - Lattermann R AU - Schricker T FA - Sato, Tamaki FA - Carvalho, George FA - Sato, Hiroaki FA - Lattermann, Ralph FA - Schricker, Thomas IN - Sato, Tamaki. Department of Anaesthesia, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, Canada. TI - Glucose and insulin administration while maintaining normoglycemia during cardiac surgery using a computer-assisted algorithm. SO - Diabetes Technology & Therapeutics. 13(1):79-84, 2011 Jan AS - Diabetes Technol Ther. 13(1):79-84, 2011 Jan NJ - Diabetes technology & therapeutics PI - Journal available in: Print PI - Citation processed from: Internet JC - 100889084, d3x IO - Diabetes Technol. Ther. SB - Index Medicus CP - United States MH - Aged MH - Algorithms MH - *Blood Glucose/me [Metabolism] MH - *Cardiac Surgical Procedures/mt [Methods] MH - Female MH - *Glucose/ad [Administration & Dosage] MH - Humans MH - Hyperglycemia/pc [Prevention & Control] MH - Hypoglycemia/pc [Prevention & Control] MH - *Insulin/ad [Administration & Dosage] MH - Male MH - Middle Aged MH - Software AB - BACKGROUND: applying the principles of the hyperinsulinemic-normoglycemic clamp technique we have introduced glucose and insulin administration while maintaining normoglycemia (GIN therapy) to surgical patients. The objective of this study was to evaluate a novel computer software (GIN Computer Software [GINCS]) program using an algorithm based on the original clamp equation and modified for its use during cardiac surgery. AB - METHODS: thirty-six patients without diabetes undergoing elective cardiac surgery were randomly assigned to manually controlled or computer-guided GIN therapy. In both groups insulin was administered at 5mU/kg/min during surgery. Simultaneously, 20% dextrose was infused at a rate adjusted to maintain blood glucose (BG) between 4.0 and 6.0mmol/L. The adjustments were made either following an algorithm based on our previous GIN experience or suggestions made by the software program. The primary outcome was the achievement of target glycemia. AB - RESULTS: normoglycemia was achieved in both groups as reflected by mean BG concentrations of 5.0+/-0.5mmol/L and 5.1+/-0.2mmol/L. Mean sampling intervals were longer in the GINCS group than in the manual group (21.5 +/-1.9 vs. 14.2+/-2.2min, P<0.001). The GINCS therapy was associated with a greater percentage of BG measurements within target (manual group, before cardiopulmonary bypass [CPB] 79.7%, during CPB 68.1%, and after CPB 69.1%; GINCS group, before CPB 94.1%, during CPB 92.4%, and after CPB 97.7%; P<0.001). No hypoglycemia was observed. AB - CONCLUSIONS: the use of a computer-guided GIN protocol in patients without diabetes undergoing open heart surgery provided excellent and safe glycemic control. RN - 0 (Blood Glucose) RN - 0 (Insulin) RN - IY9XDZ35W2 (Glucose) ES - 1557-8593 IL - 1520-9156 DO - https://dx.doi.org/10.1089/dia.2010.0093 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 21175276 [pubmed] ID - 10.1089/dia.2010.0093 [doi] PP - ppublish LG - English DP - 2011 Jan DC - 20101223 EZ - 2010/12/24 06:00 DA - 2011/04/20 06:00 DT - 2010/12/24 06:00 YR - 2011 ED - 20110419 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21175276 <422. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21335125 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ruckert JC AU - Swierzy M AU - Ismail M FA - Ruckert, Jens C FA - Swierzy, Marc FA - Ismail, Mahmoud IN - Ruckert, Jens C. Department of General, Visceral, Vascular and Thoracic Surgery, Universitatsmedizin Berlin, Charite Campus Mitte, Berlin, Germany. jens-c.rueckert@charite.de TI - Comparison of robotic and nonrobotic thoracoscopic thymectomy: a cohort study. SO - Journal of Thoracic & Cardiovascular Surgery. 141(3):673-7, 2011 Mar AS - J Thorac Cardiovasc Surg. 141(3):673-7, 2011 Mar NJ - The Journal of thoracic and cardiovascular surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - k9j, 0376343 IO - J. Thorac. Cardiovasc. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adolescent MH - Adult MH - Aged MH - Atrophy MH - Child MH - Female MH - Germany MH - Humans MH - Hyperplasia MH - Kaplan-Meier Estimate MH - Male MH - Middle Aged MH - Myasthenia Gravis/pa [Pathology] MH - *Myasthenia Gravis/su [Surgery] MH - Retrospective Studies MH - *Robotics MH - Severity of Illness Index MH - Surgery, Computer-Assisted/ae [Adverse Effects] MH - *Surgery, Computer-Assisted MH - Thoracoscopy/ae [Adverse Effects] MH - *Thoracoscopy MH - Thymectomy/ae [Adverse Effects] MH - *Thymectomy/mt [Methods] MH - Thymus Gland/pa [Pathology] MH - *Thymus Gland/su [Surgery] MH - Treatment Outcome MH - Young Adult AB - OBJECTIVE: Radical thymectomy has become more popular in the comprehensive treatment of myasthenia gravis. Minimally invasive techniques are increasingly used for thymectomy. The most recent development in robotic thoracoscopic surgery has been successfully applied for mediastinal pathologies. To establish robotic technique as a standard, the results of high-volume centers and comparison with traditional surgery are mandatory. AB - METHODS: In a retrospective cohort study, the results of 79 thoracoscopic thymectomies (October 1994 to December 2002) were compared with the results of 74 robotic thoracoscopic thymectomies (January 2003 to August 2006). Data from both series were collected prospectively. In both groups, all patients had myasthenia gravis. Both cohorts were compared with respect to severity of disease, gender, age, histology, and postoperative morbidity. All patients were analyzed for quantification of improvement of disease according to the Myasthenia Gravis Foundation of America. AB - RESULTS: There were no differences in age distribution and severity of myasthenia gravis. The dominant histologic finding was follicular hyperplasia of the thymus in both groups with a significantly higher percentage in the thoracoscopic thymectomy series (68% vs 45%, P < .001). After a follow-up of 42 months, the cumulative complete remission rate of myasthenia gravis for robotic and nonrobotic thymectomy was 39.25% and 20.3% (P = .01), respectively. AB - CONCLUSIONS: There is an improved outcome for myasthenia gravis after robotic thoracoscopic thymectomy compared with thoracoscopic thymectomy. AB - Copyright © 2011 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved. ES - 1097-685X IL - 0022-5223 DI - S0022-5223(10)01399-1 DO - https://dx.doi.org/10.1016/j.jtcvs.2010.11.042 PT - Comparative Study PT - Journal Article ID - 21335125 [pubmed] ID - S0022-5223(10)01399-1 [pii] ID - 10.1016/j.jtcvs.2010.11.042 [doi] PP - ppublish PH - 2010/05/10 [received] PH - 2010/11/17 [revised] PH - 2010/11/29 [accepted] LG - English DP - 2011 Mar DC - 20110221 EZ - 2011/02/22 06:00 DA - 2011/04/09 06:00 DT - 2011/02/22 06:00 YR - 2011 ED - 20110408 RD - 20110221 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med7&AN=21335125 <423. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21087128 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Engel JD AU - Kao WW AU - Williams SB AU - Hong YM FA - Engel, Jason D FA - Kao, William W FA - Williams, Stephen B FA - Hong, Y Mark IN - Engel, Jason D. Department of Urology, George Washington University Hospital, Washington, District of Columbia 20006, USA. jengel@dcurology.net TI - Oncologic outcome of robot-assisted laparoscopic prostatectomy in the high-risk setting. SO - Journal of Endourology. 24(12):1963-6, 2010 Dec AS - J Endourol. 24(12):1963-6, 2010 Dec NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Aged MH - Cohort Studies MH - Disease-Free Survival MH - Humans MH - *Laparoscopy MH - Male MH - Middle Aged MH - *Prostatectomy/mt [Methods] MH - Risk Factors MH - *Robotics/mt [Methods] MH - Treatment Outcome AB - BACKGROUND AND PURPOSE: Previous studies have demonstrated the feasibility of open radical prostatectomy in the high-risk setting. Management of high-risk disease with robot-assisted laparoscopic radical prostatectomy (RALP) is controversial. We examined biochemical recurrence in a selected cohort of high-risk patients who were undergoing RALP. AB - PATIENTS AND METHODS: Men with high-risk prostate cancer who underwent bilateral nerve-sparing, nonsalvage RALP by a single surgeon without adjuvant or neoadjuvant therapy of any kind were identified. High risk was defined by preoperative prostate-specific antigen (PSA) level >10 ng/dL, Gleason score >8 on final pathologic evaluation, or stage >pT(3). Postoperative PSA value >0.2 ng/dL defined biochemical recurrence. AB - RESULTS: A total of 73 men were identified. There was no significant difference in surgical margin positivity (38% overall) or prostate size between recurrence and nonrecurrence cohorts. Biochemical failure was significantly associated with higher pathologic Gleason score (P = 0.0085) but not pathologic stage (P = 0.22) or preoperative PSA level (P = 0.18). With follow-up to 85 months (mean 31.8 mos), biochemical recurrence-free survival was 77% with mean time to recurrence of 7.7 months. Recurrence occurred significantly earlier than later (P < 0.001). AB - CONCLUSIONS: Reasonable short- to intermediate-term biochemical outcomes can be achieved in a recurrence-prone group of high-risk men who are undergoing RALP. RALP is feasible in a selected cohort of high-risk men who are undergoing aggressive local therapy. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2010.0305 PT - Clinical Trial PT - Journal Article ID - 21087128 [pubmed] ID - 10.1089/end.2010.0305 [doi] PP - ppublish LG - English EP - 20101118 DP - 2010 Dec DC - 20101214 EZ - 2010/11/20 06:00 DA - 2011/03/31 06:00 DT - 2010/11/23 06:00 YR - 2010 ED - 20110330 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=21087128 <424. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20973740 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tan G AU - Srivastava A AU - Grover S AU - Peters D AU - Dorsey P Jr AU - Scott A AU - Jhaveri J AU - Tilki D AU - Te A AU - Tewari A FA - Tan, Gerald FA - Srivastava, Abhishek FA - Grover, Sonal FA - Peters, David FA - Dorsey, Philip Jr FA - Scott, Ann FA - Jhaveri, Jay FA - Tilki, Derya FA - Te, Alexis FA - Tewari, Ashutosh IN - Tan, Gerald. Department of Urology, Weill Medical College of Cornell University, New York Presbyterian Hospital, LeFrak Center of Robotic Surgery and Institute of Prostate Cancer, James Buchanan Brady Foundation, New York, New York 10065, USA. TI - Optimizing vesicourethral anastomosis healing after robot-assisted laparoscopic radical prostatectomy: lessons learned from three techniques in 1900 patients. CM - Comment in: Nat Rev Urol. 2011 Mar;8(3):118; PMID: 21513015 SO - Journal of Endourology. 24(12):1975-83, 2010 Dec AS - J Endourol. 24(12):1975-83, 2010 Dec NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Anastomosis, Surgical/ae [Adverse Effects] MH - *Anastomosis, Surgical/mt [Methods] MH - Biopsy MH - Demography MH - Humans MH - *Laparoscopy MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Postoperative Complications/et [Etiology] MH - Preoperative Care MH - Prostate/pa [Pathology] MH - Prostate/su [Surgery] MH - *Prostatectomy/mt [Methods] MH - *Robotics/mt [Methods] MH - Time Factors MH - *Urethra/su [Surgery] MH - Urinary Bladder/su [Surgery] MH - Urinary Bladder Neck Obstruction/pp [Physiopathology] MH - Urinary Bladder Neck Obstruction/su [Surgery] MH - *Wound Healing AB - BACKGROUND AND PURPOSE: Creation of an optimally apposed, tension-free, well-supported vesicourethral anastomosis remains the cornerstone for anastomotic healing after radical prostatectomy. We report the effect of three techniques of bladder neck reconstruction during robot-assisted radical prostatectomy on anastomotic leak, stricture formation, and continence recovery. AB - PATIENTS AND METHODS: Between January 2005 to September 2009, 1900 consecutive patients underwent robotic-assisted laparoscopic prostatectomy (RALP) by a single surgeon. Of these, the first 214 underwent vesicourethral conventional anastomosis (CA); the next 303 men underwent anterior reconstruction (AR) only; and last 1383 men underwent total anatomic restoration (TR). Data elements included patient age, body mass index, preoperative biopsy Gleason score and prostate-specific antigen level, prostate volume, total operative time, console time, time for performing vesicourethral anastomosis, estimated blood loss, tumor stage, and margin status on final pathologic findings. Primary end points were rates of clinically significant anastomotic leaks, bladder neck contractures, and time to return of continence. Chi-square and Fisher exact tests were used for analysis of categoric variables. The Cox proportional hazard model was used for both univariate and multivariate analysis. AB - RESULTS: Clinically significant anastomotic leakage and bladder neck strictures were significantly fewer in the reconstructed groups (2.3% vs 1.0% vs 0.3% and 3.7% vs 1.3% vs 0.5% in the CA, AR, and TR groups, P < 0.01). Continence rates at 1, 6, 12, 26, and 52 weeks after RALP were also significantly better at all time points with AR and TR compared with CA alone (P < 0.001). AB - CONCLUSIONS: TR of the continence mechanism optimizes vesicourethral anastomosis healing and hastens early continence return after RALP. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2009.0630 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 20973740 [pubmed] ID - 10.1089/end.2009.0630 [doi] PP - ppublish LG - English EP - 20101025 DP - 2010 Dec DC - 20101214 EZ - 2010/10/27 06:00 DA - 2011/03/31 06:00 DT - 2010/10/27 06:00 YR - 2010 ED - 20110330 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20973740 <425. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20932190 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Xylinas E AU - Ouzaid I AU - Durand X AU - Ploussard G AU - Salomon L AU - Gillion N AU - Vordos D AU - Hoznek A AU - Abbou CC AU - de la Taille A FA - Xylinas, Evanguelos FA - Ouzaid, Idir FA - Durand, Xavier FA - Ploussard, Guillaume FA - Salomon, Laurent FA - Gillion, Norman FA - Vordos, Dimitri FA - Hoznek, Andras FA - Abbou, Clement-Claude FA - de la Taille, Alexandre IN - Xylinas, Evanguelos. Departments of Urology and Pathology APHP, CHU Henri Mondor , Creteil, France . TI - Robot-assisted laparoscopic sacral colpopexy: initial experience in a high-volume laparoscopic reference center. SO - Journal of Endourology. 24(12):1985-9, 2010 Dec AS - J Endourol. 24(12):1985-9, 2010 Dec NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Aged MH - Female MH - Humans MH - *Laparoscopy MH - Middle Aged MH - Perioperative Care MH - Postoperative Complications/et [Etiology] MH - Recurrence MH - *Referral and Consultation MH - *Robotics/mt [Methods] MH - *Sacrum/su [Surgery] MH - Surgical Instruments MH - Treatment Outcome MH - *Urologic Surgical Procedures/mt [Methods] AB - PURPOSE: To describe the surgical technique of robot-assisted sacral colpopexy (RASCP) and to assess its feasibility and safety in a high-volume laparoscopic center. AB - PATIENT AND METHODS: 12 women with symptomatic urogenital prolapse with or without concomitant urinary stress incontinence were treated with RASCP by one surgeon at our institution. The preoperative workup involved a detailed urologica and gynecologic history and physical examination to determine the type, the degree of the prolapse and the presence of concomitant stress urinary incontinence. AB - RESULTS: Mean operative time was 144 minutes (range 120-180 min). No conversion to a laparoscopic or open procedure was necessary. The mean patient age was 57.1 years old (range 44-79). The mean estimated blood loss was 60 mL (range 20-200 mL). The mean catheterization time was 2 days, and the mean hospital stay was 3.4 days (range 3-4 d). At a mean follow-up of 19.1 months (range 8-28 mos), no recurrence of the prolapse occurred. AB - CONCLUSION: RASCP for treatment of patients with urogenital prolapse is a feasible alternative to open and laparoscopic procedures. It procures an anatomic repositioning of the pelvic organs. The short-term results and the complication rates are similar with gold standard techniques. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2010.0160 PT - Clinical Trial PT - Journal Article ID - 20932190 [pubmed] ID - 10.1089/end.2010.0160 [doi] PP - ppublish LG - English EP - 20101009 DP - 2010 Dec DC - 20101214 EZ - 2010/10/12 06:00 DA - 2011/03/31 06:00 DT - 2010/10/12 06:00 YR - 2010 ED - 20110330 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20932190 <426. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20974030 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lukasewycz S AU - Holman M AU - Kozlowski P AU - Porter CR AU - Odom E AU - Bernards C AU - Neil N AU - Corman JM FA - Lukasewycz, Stephen FA - Holman, Matt FA - Kozlowski, Paul FA - Porter, Christopher R FA - Odom, Erin FA - Bernards, Chris FA - Neil, Nancy FA - Corman, John M IN - Lukasewycz, Stephen. Virginia Mason Medical Center, Seattle, Washington 98111, USA. TI - Does a perioperative belladonna and opium suppository improve postoperative pain following robotic assisted laparoscopic radical prostatectomy? Results of a single institution randomized study. SO - Canadian Journal of Urology. 17(5):5377-82, 2010 Oct AS - Can J Urol. 17(5):5377-82, 2010 Oct NJ - The Canadian journal of urology PI - Journal available in: Print PI - Citation processed from: Internet JC - 9515842, dyg IO - Can J Urol SB - Index Medicus CP - Canada MH - Aged MH - Analgesia, Patient-Controlled MH - *Analgesics, Opioid/ad [Administration & Dosage] MH - Analgesics, Opioid/tu [Therapeutic Use] MH - *Atropa belladonna MH - Atropine/ad [Administration & Dosage] MH - Atropine/tu [Therapeutic Use] MH - Double-Blind Method MH - Humans MH - Laparoscopy MH - Male MH - Middle Aged MH - *Morphine/ad [Administration & Dosage] MH - *Muscarinic Antagonists/ad [Administration & Dosage] MH - Muscarinic Antagonists/tu [Therapeutic Use] MH - *Pain, Postoperative/dt [Drug Therapy] MH - Pain, Postoperative/ec [Economics] MH - Phytotherapy/ec [Economics] MH - *Phytotherapy MH - *Plant Preparations/ad [Administration & Dosage] MH - Plant Preparations/tu [Therapeutic Use] MH - Preoperative Care/ec [Economics] MH - *Preoperative Care/mt [Methods] MH - *Prostatectomy/ae [Adverse Effects] MH - Prostatic Neoplasms/su [Surgery] MH - Robotics MH - Scopolamine Hydrobromide/ad [Administration & Dosage] MH - Scopolamine Hydrobromide/tu [Therapeutic Use] MH - Suppositories AB - INTRODUCTION: Robotic assisted laparoscopic radical prostatectomy (RALP) is a common treatment for localized prostate cancer. Despite a primary advantage of improved postoperative pain, patients undergoing RALP still experience discomfort. Belladonna, containing the muscarinic receptor antagonists atropine and scopolamine, in combination with opium as a rectal suppository (B & O) may improve post-RALP pain. This study evaluates whether a single preoperative B & O results in decreased postoperative patient-reported pain and analgesic requirements. AB - MATERIALS AND METHODS: Patients undergoing RALP at Virginia Mason Medical Center between November 2008 and July 2009 were offered the opportunity to enter a randomized, double-blind, placebo-controlled trial. Exclusion criteria included: glaucoma, bronchial asthma, convulsive disorders, chronic pain, chronic use of analgesics, or a history of alcohol or opioid dependency. Surgeons were blinded to suppository placement which was administered after induction of anesthesia. All patients underwent a standardized anesthesia regimen. Postoperative pain was assessed by a visual analog scale (VAS) and postoperative narcotic use was calculated in intravenous morphine equivalents. AB - RESULTS: Ninety-nine patients were included in the analysis. The B & O and control groups were not significantly different in terms of age, body mass index, operative time, nerve sparing status or prostatic volume. Postoperative pain was significantly improved during the first two postoperative hours in the B & O group. Similarly, 24-hour morphine consumption was significantly lower in patients who received a B & O. No adverse effects secondary to suppository placement were identified. AB - CONCLUSION: Preoperative administration of B & O suppository results in significantly decreased postoperative pain and 24-hour morphine consumption in patients undergoing RALP. RN - 0 (Analgesics, Opioid) RN - 0 (Muscarinic Antagonists) RN - 0 (Plant Preparations) RN - 0 (Suppositories) RN - 451IFR0GXB (Scopolamine Hydrobromide) RN - 76I7G6D29C (Morphine) RN - 7C0697DR9I (Atropine) IS - 1195-9479 IL - 1195-9479 PT - Journal Article PT - Randomized Controlled Trial ID - 20974030 [pubmed] PP - ppublish LG - English DP - 2010 Oct DC - 20101026 EZ - 2010/10/27 06:00 DA - 2011/02/26 06:00 DT - 2010/10/27 06:00 YR - 2010 ED - 20110225 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20974030 <427. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 21051979 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Vaknin Z AU - Perri T AU - Lau S AU - Deland C AU - Drummond N AU - Rosberger Z AU - Gourdji I AU - Gotlieb WH FA - Vaknin, Zvi FA - Perri, Tamar FA - Lau, Susie FA - Deland, Claire FA - Drummond, Nancy FA - Rosberger, Zeev FA - Gourdji, Iris FA - Gotlieb, Walter H IN - Vaknin, Zvi. Division of Gynecologic Oncology, Department of Nursing, Segal Cancer Center, Jewish General Hospital, Montreal, Quebec, Canada. TI - Outcome and quality of life in a prospective cohort of the first 100 robotic surgeries for endometrial cancer, with focus on elderly patients. SO - International Journal of Gynecological Cancer. 20(8):1367-73, 2010 Nov AS - Int J Gynecol Cancer. 20(8):1367-73, 2010 Nov NJ - International journal of gynecological cancer : official journal of the International Gynecological Cancer Society PI - Journal available in: Print PI - Citation processed from: Internet JC - dzp, 9111626 IO - Int. J. Gynecol. Cancer SB - Index Medicus CP - United States MH - Adult MH - Age Factors MH - *Aged MH - Aged, 80 and over MH - Carcinoma, Endometrioid/di [Diagnosis] MH - Carcinoma, Endometrioid/px [Psychology] MH - *Carcinoma, Endometrioid/su [Surgery] MH - Cohort Studies MH - Endometrial Neoplasms/di [Diagnosis] MH - Endometrial Neoplasms/px [Psychology] MH - *Endometrial Neoplasms/su [Surgery] MH - Female MH - *Gynecologic Surgical Procedures/is [Instrumentation] MH - Gynecologic Surgical Procedures/mt [Methods] MH - Gynecologic Surgical Procedures/rh [Rehabilitation] MH - Humans MH - Middle Aged MH - Minimally Invasive Surgical Procedures/rh [Rehabilitation] MH - Prognosis MH - *Quality of Life MH - Robotics/mt [Methods] MH - *Robotics MH - Treatment Outcome AB - OBJECTIVE: Evaluation of surgical outcomes, including quality of life, in patients with endometrial cancer in the early phase of implementation of a robotic surgery program, comparing elderly with younger patients. AB - METHODS: Prospective evaluation of perioperative data and a postoperative quality-of-life survey of the first 100 robotic surgeries for endometrial cancer performed in the Division of Gynecologic Oncology at a tertiary cancer center. Women were divided in 2 groups based on age, allowing comparison of outcomes between the elderly (>70 years) and younger groups (<70 years). AB - RESULTS: Of the first 100 patients, 41 were elderly (mean age, 78 years). The elderly group had significantly higher number of comorbidities and more advanced disease when compared with the younger women. Despite this, elderly women had similar mean operative times (252 vs 243 minutes), mean console times (171 vs 175 minutes), and mean blood loss (83 vs 81 mL) as compared with the younger group. Conversion rate to minilaparotomy was 6%, all of which were performed at the end of surgery for the removal of enlarged uteri that could not be delivered vaginally. The overall perioperative complication rates were not statistically different between the age groups. Median hospital stay tended to be longer for the elderly women (2 vs 1 day) but was not statistically significant. The postoperative quality-of-life assessment revealed that patients young and old alike were highly satisfied with the procedure. AB - CONCLUSIONS: Prospective evaluation indicates that even in the early phases of implementation of a robotic surgical program for endometrial cancer, the procedure seems safe and confers an excellent quality of life for elderly patients. ES - 1525-1438 IL - 1048-891X DI - 00009577-201011000-00016 DO - https://dx.doi.org/10.1111/IGC.0b013e3181f2950a PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 21051979 [pubmed] ID - 10.1111/IGC.0b013e3181f2950a [doi] ID - 00009577-201011000-00016 [pii] PP - ppublish LG - English DP - 2010 Nov DC - 20101105 EZ - 2010/11/06 06:00 DA - 2011/02/25 06:00 DT - 2010/11/06 06:00 YR - 2010 ED - 20110224 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=21051979 <428. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20877308 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Silberstein JL AU - Parsons JK AU - Palazzi-Churas K AU - Downs TM AU - Sakamoto K AU - Derweesh IH AU - Woldrich J AU - Kane CJ FA - Silberstein, J L FA - Parsons, J K FA - Palazzi-Churas, K FA - Downs, T M FA - Sakamoto, K FA - Derweesh, I H FA - Woldrich, J FA - Kane, C J IN - Silberstein, J L. Division of Urology, University of California San Diego, San Diego, CA 92103-8897, USA. leparker@ucsd.edu TI - Robot-assisted laparoscopic radical prostatectomy in men with human immunodeficiency virus. SO - Prostate Cancer & Prostatic Diseases. 13(4):328-32, 2010 Dec AS - Prostate Cancer Prostatic Dis. 13(4):328-32, 2010 Dec NJ - Prostate cancer and prostatic diseases PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 9815755 IO - Prostate Cancer Prostatic Dis. SB - Index Medicus CP - England MH - Adult MH - Aged MH - Carcinoma/co [Complications] MH - *Carcinoma/su [Surgery] MH - HIV/ph [Physiology] MH - HIV Infections/co [Complications] MH - *HIV Infections/su [Surgery] MH - Humans MH - Laparoscopy/is [Instrumentation] MH - *Laparoscopy/mt [Methods] MH - Length of Stay/sn [Statistics & Numerical Data] MH - Male MH - Middle Aged MH - Postoperative Complications/ep [Epidemiology] MH - Prostatectomy/is [Instrumentation] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/co [Complications] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotics/mt [Methods] AB - The aim of this study is to evaluate the outcomes of robot-assisted laparoscopic prostatectomy (RALP) in prostate cancer (PCa) patients with human immunodeficiency virus (HIV). This is a prospective cohort study of HIV patients undergoing RALP, comparing the demographics, tumor characteristics, complications, and short-term oncological outcomes of HIV-positive men to HIV-negative men using univariate (chi(2), Mann-Whitney test) and multivariable (logistic regression) analyses. From 2007 to 2010, 298 men underwent RALP, 8 of whom were known to be HIV positive. Preoperatively, all eight were taking highly active antiretroviral therapy (HAART) and had undetectable viral loads (<50); mean CD4 count was 634 cells per mm(3). HIV-positive men were younger (54 versus 62 years, P=0.010) and less likely to be white (P=0.007). There were no significant differences between groups with respect to clinical staging, pathological and oncological outcomes or most complication rates. However, the prevalence of perioperative transfusions (P=0.031) and ileus (P=0.021) were higher in HIV-positive patients. HIV remained significantly associated with risk of transfusion after adjustment for age, race, Gleason sum and clinical T stage (P=0.002). After a median of 2.6 (range 0.03-19.2) months of follow-up, PSA remained undetectable in all eight HIV patients. These data suggest that RALP is safe for, and demonstrates short-term oncological efficacy in, HIV-positive patients with PCa. ES - 1476-5608 IL - 1365-7852 DI - pcan201035 DO - https://dx.doi.org/10.1038/pcan.2010.35 PT - Clinical Trial PT - Journal Article ID - 20877308 [pubmed] ID - pcan201035 [pii] ID - 10.1038/pcan.2010.35 [doi] PP - ppublish LG - English EP - 20100928 DP - 2010 Dec DC - 20101111 EZ - 2010/09/30 06:00 DA - 2011/02/25 06:00 DT - 2010/09/30 06:00 YR - 2010 ED - 20110224 RD - 20101111 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20877308 <429. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20409064 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Koivunen M AU - Valimaki M AU - Patel A AU - Knapp M AU - Hatonen H AU - Kuosmanen L AU - Pitkanen A AU - Anttila M AU - Katajisto J FA - Koivunen, Marita FA - Valimaki, Maritta FA - Patel, Anita FA - Knapp, Martin FA - Hatonen, Heli FA - Kuosmanen, Lauri FA - Pitkanen, Anneli FA - Anttila, Minna FA - Katajisto, Jouko IN - Koivunen, Marita. Department of Nursing Science, University of Turku, Turku, Finland. mh.koivu@gmail.com TI - Effects of the implementation of the web-based patient support system on staff's attitudes towards computers and IT use: a randomised controlled trial. SO - Scandinavian Journal of Caring Sciences. 24(3):592-9, 2010 Sep AS - Scand J Caring Sci. 24(3):592-9, 2010 Sep NJ - Scandinavian journal of caring sciences PI - Journal available in: Print PI - Citation processed from: Internet JC - sjo, 8804206 IO - Scand J Caring Sci SB - Nursing Journal CP - Sweden MH - Adult MH - *Attitude of Health Personnel MH - *Attitude to Computers MH - Female MH - Finland MH - Hospitals, Psychiatric MH - Humans MH - *Internet MH - Male MH - Middle Aged MH - Nursing Staff, Hospital AB - Utilisation of information technology (IT) in the treatment of people with severe mental health problems is an unknown area in Europe. Use of IT and guiding patients to relevant sources of health information requires that nursing staff have positive attitudes toward computers and accept IT use as a part of daily practises. The aim of the study was to assess the effects of the implementation of a web-based patient support system on staff's attitudes towards computers and IT use on psychiatric wards. Hundred and forty-nine nurses in two psychiatric hospitals in Finland were randomised to two groups to deliver patient education for patients with schizophrenia and psychosis with a web-based system (n = 76) or leaflets (n = 73). After baseline nurses were followed-up for 18 months after the introduction of the system. The primary outcome was nurses' motivation to utilise computers, and the secondary outcomes were nurses' beliefs in and satisfaction with computers, and use of computer and internet. There were no statistically significant differences between study groups in attitudes towards computers (motivation p = 0.936, beliefs p = 0.270, satisfaction p = 0.462) and internet use (p = 0.276). However, nurses' general computer use (p = 0.029) increased more in the leaflet group than in the IT intervention group. We can conclude that IT has promise as an alternative method in patient education, as the implementation of the web-based patient support system in daily basis did not have a negative effect on nurses' attitudes towards IT. AB - Copyright © 2010 The Authors. Journal compilation © 2010 Nordic College of Caring Science. ES - 1471-6712 IL - 0283-9318 DI - SCS755 DO - https://dx.doi.org/10.1111/j.1471-6712.2009.00755.x PT - Journal Article PT - Randomized Controlled Trial ID - 20409064 [pubmed] ID - SCS755 [pii] ID - 10.1111/j.1471-6712.2009.00755.x [doi] PP - ppublish LG - English DP - 2010 Sep DC - 20101105 EZ - 2010/04/23 06:00 DA - 2011/02/18 06:00 DT - 2010/04/23 06:00 YR - 2010 ED - 20110217 RD - 20101105 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20409064 <430. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20716619 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Allen JD AU - Othus MK AU - Hart A Jr AU - Tom L AU - Li Y AU - Berry D AU - Bowen D FA - Allen, Jennifer D FA - Othus, Megan K D FA - Hart, Alton Jr FA - Tom, Laura FA - Li, Yi FA - Berry, Donna FA - Bowen, Deborah IN - Allen, Jennifer D. Dana-Farber Cancer Institute, Harvard MedicalSchool, School of Public Health, Boston, Massachusetts, USA. jennifer_allen@dfci.harvard.edu TI - A randomized trial of a computer-tailored decision aid to improve prostate cancer screening decisions: results from the Take the Wheel trial. SO - Cancer Epidemiology, Biomarkers & Prevention. 19(9):2172-86, 2010 Sep AS - Cancer Epidemiol Biomarkers Prev. 19(9):2172-86, 2010 Sep NJ - Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - bnj, 9200608 IO - Cancer Epidemiol. Biomarkers Prev. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386842 OI - Source: NLM. HHSPA675926 SB - Index Medicus CP - United States MH - Cohort Studies MH - *Decision Making, Computer-Assisted MH - *Early Detection of Cancer/mt [Methods] MH - Humans MH - Male MH - Middle Aged MH - Patient Education as Topic/mt [Methods] MH - *Prostatic Neoplasms/di [Diagnosis] AB - OBJECTIVE: To evaluate a decision aid (DA) designed to promote informed decision making for prostate cancer screening. AB - METHODS: Twelve work sites were randomly assigned to an intervention or nonintervention comparison condition. Intervention sites received access to a computer-tailored DA at the workplace. Male employees age 45 years and above (n = 625) completed surveys at baseline and at 3-month follow-up, documenting aspects of informed decision making. AB - RESULTS: Using an intention-to-treat analysis, men in the intervention group were significantly more likely to have made a screening decision and to have improved knowledge without increased decisional conflict, relative to men in the comparison group. These changes were observed despite the fact that only 30% of men in intervention sites used the DA. Among DA users, similar improvements were observed, although the magnitudes of changes were substantially greater, and significant improvements in decision self-efficacy were observed. AB - CONCLUSIONS: A DA offered in the workplace promoted decision making, improved knowledge, and increased decision self-efficacy among users, without increasing decisional conflict. However, participation was suboptimal, suggesting that better methods for engaging men in workplace interventions are needed. IMPACT STATEMENT: This trial shows the efficacy of a computer-tailored DA in promoting informed decisions about prostate cancer screening. The DA was delivered through work sites, thereby providing access to resources required to participate in informed decision making without requiring a medical appointment. However, participation rates were suboptimal, and additional strategies for engaging men are needed. AB - Copyright (c)2010 AACR. ES - 1538-7755 IL - 1055-9965 DI - 1055-9965.EPI-09-0410 DO - https://dx.doi.org/10.1158/1055-9965.EPI-09-0410 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, U.S. Gov't, P.H.S. ID - 20716619 [pubmed] ID - 1055-9965.EPI-09-0410 [pii] ID - 10.1158/1055-9965.EPI-09-0410 [doi] ID - PMC4386842 [pmc] ID - HHSPA675926 [mid] PP - ppublish GI - No: T32 CA009337 Organization: (CA) *NCI NIH HHS* Country: United States No: U48 DP000064 Organization: (DP) *NCCDPHP CDC HHS* Country: United States No: 3U48DP000064-01S1 Organization: (DP) *NCCDPHP CDC HHS* Country: United States LG - English EP - 20100817 DP - 2010 Sep DC - 20100909 EZ - 2010/08/19 06:00 DA - 2011/02/09 06:00 DT - 2010/08/19 06:00 YR - 2010 ED - 20110208 RD - 20161019 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20716619 <431. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20818988 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tewari AK AU - Srivastava A AU - Sooriakumaran P AU - Slevin A AU - Grover S AU - Waldman O AU - Rajan S AU - Herman M AU - Berryhill R Jr AU - Leung R FA - Tewari, Ashutosh K FA - Srivastava, Abhishek FA - Sooriakumaran, Prasanna FA - Slevin, Adam FA - Grover, Sonal FA - Waldman, Olivia FA - Rajan, Sivaram FA - Herman, Michael FA - Berryhill, Roy Jr FA - Leung, Robert IN - Tewari, Ashutosh K. LeFrak Center of Robotic Surgery and Institute of Prostate Cancer, James Buchanan Brady Foundation, Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10065, USA. ashtewarimd@gmail.com TI - Use of a novel absorbable barbed plastic surgical suture enables a "self-cinching" technique of vesicourethral anastomosis during robot-assisted prostatectomy and improves anastomotic times. SO - Journal of Endourology. 24(10):1645-50, 2010 Oct AS - J Endourol. 24(10):1645-50, 2010 Oct NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Anastomosis, Surgical/mt [Methods] MH - Equipment Design MH - Feasibility Studies MH - Humans MH - Male MH - Middle Aged MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Robotics MH - *Sutures MH - Time Factors MH - *Urethra/su [Surgery] MH - *Urinary Bladder/su [Surgery] AB - PURPOSE: To demonstrate a novel technique of self-cinching anastomosis using a barbed and looped suture during robot-assisted radical prostatectomy (RARP). AB - PATIENTS AND METHODS: This is a feasibility study of 50 consecutive patients who underwent this novel self-cinching anastomotic technique using a V-LocTM 180 absorbable barbed suture after RARP for clinically localized prostate cancer. The results were then compared with 50 consecutive patients who underwent RARP by the same surgeon before this new technique. We examined whether this novel technique had any effects on posterior reconstruction time, vesicourethral anastomosis time, and thus total reconstruction and operative time by inference. AB - RESULTS: The V-Loc 180 group had significantly shorter posterior reconstruction (40 seconds vs 60 seconds; P < 0.001) and vesicourethral anastomotic times (7 min vs 12 min; P < 0.001). By inference, this meant that total reconstruction and operative times were also significantly less (8 minutes vs 13.5 min; P < 0.001 and 106 min vs 114.5 minutes; P < 0.001, respectively). AB - CONCLUSION: We have shown that this technique is feasible and improves posterior reconstruction and anastomotic times. Further follow-up will determine any benefits of this technique on anastomotic urinary leak rates, continence, and catheter removal times. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2010.0316 PT - Clinical Trial PT - Journal Article ID - 20818988 [pubmed] ID - 10.1089/end.2010.0316 [doi] PP - ppublish LG - English DP - 2010 Oct DC - 20101011 EZ - 2010/09/08 06:00 DA - 2011/02/02 06:00 DT - 2010/09/08 06:00 YR - 2010 ED - 20110201 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20818988 <432. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20362386 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Joshi N AU - de Blok W AU - van Muilekom E AU - van der Poel H FA - Joshi, Neil FA - de Blok, Willem FA - van Muilekom, Erik FA - van der Poel, Henk IN - Joshi, Neil. Department of Urology, Netherlands Cancer Institute, Amsterdam, The Netherlands. TI - Impact of posterior musculofascial reconstruction on early continence after robot-assisted laparoscopic radical prostatectomy: results of a prospective parallel group trial. SO - European Urology. 58(1):84-9, 2010 Jul AS - Eur Urol. 58(1):84-9, 2010 Jul NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Anastomosis, Surgical/mt [Methods] MH - Fasciotomy MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - Postoperative Complications/di [Diagnosis] MH - Prostate/pa [Pathology] MH - Prostate/su [Surgery] MH - Prostate-Specific Antigen/bl [Blood] MH - *Prostatectomy/ae [Adverse Effects] MH - Prostatic Neoplasms/su [Surgery] MH - Quality of Life MH - *Robotics/mt [Methods] MH - Surveys and Questionnaires MH - Treatment Outcome MH - *Urinary Incontinence/et [Etiology] MH - *Urinary Incontinence/su [Surgery] AB - BACKGROUND: A significant proportion of patients develop urinary incontinence early after radical prostatectomy. Posterior reconstruction of supporting tissues has been found to reduce incontinence in open and conventional laparoscopic prostatectomy series. AB - OBJECTIVE: To investigate whether our version of a posterior musculofascial reconstruction will reduce early incontinence and have a beneficial effect on patients' quality of life (QoL). AB - DESIGN, SETTING, AND PARTICIPANTS: One hundred seven consecutive patients undergoing primary robot-assisted radical laparoscopic prostatectomy (RALP) performed by a single surgeon at one tertiary referral oncology institution were alternately assigned (not randomised) to intervention (n=53) or control groups (n=54). AB - SURGICAL PROCEDURE: RALP with median fibrous raphe reconstruction (MFRR) followed by formation of the urethrovesical anastomosis (intervention group) versus standard anastomosis without posterior reconstruction (control group). AB - MEASUREMENTS: Measurements included incontinence at baseline and 3-mo intervals; QoL as measured by a simple questionnaire, the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life-Core 30 (QLQ-C30), and Prostate Cancer Module (PR25) questionnaires preoperatively and at 6 mo postprocedure; tumour characteristics; operative time; fascial preservation score; duration of catheterisation; and anastomotic leakage on cystogram. AB - RESULTS AND LIMITATIONS: For intervention and control groups respectively, mean catheter duration was 11.74 d and 12.74 d (p=0.451); leakage on cystogram was present in six and eight cases (p=0.28); and incontinence (any involuntary urine loss) at 3 mo was 75% and 69% (p=0.391) and at 6 mo was 51% and 43% (p=0.686). Urinary retention occurred only in one case (control group). The percentage of cases returning to baseline in all QoL domains (except insomnia) was similar at 6 mo between the two groups. Short follow-up, lack of blinding, and probable small differences in our method of MFRR performed compared with other studies were identified as significant limitations. AB - CONCLUSIONS: No significant difference in any of the analysed outcome measures was observed. Posterior reconstruction of the musculofascial complex does not appear to improve early urinary incontinence after RALP. AB - Copyright 2010 European Association of Urology. Published by Elsevier B.V. All rights reserved. RN - EC 3-4-21-77 (Prostate-Specific Antigen) ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(10)00281-2 DO - https://dx.doi.org/10.1016/j.eururo.2010.03.028 PT - Journal Article PT - Randomized Controlled Trial ID - 20362386 [pubmed] ID - S0302-2838(10)00281-2 [pii] ID - 10.1016/j.eururo.2010.03.028 [doi] PP - ppublish PH - 2010/02/25 [received] PH - 2010/03/15 [accepted] LG - English EP - 20100326 DP - 2010 Jul DC - 20100909 EZ - 2010/04/06 06:00 DA - 2011/01/13 06:00 DT - 2010/04/07 06:00 YR - 2010 ED - 20110112 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20362386 <433. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20869107 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sammon JD AU - Muhletaler F AU - Peabody JO AU - Diaz-Insua M AU - Satyanaryana R AU - Menon M FA - Sammon, Jesse D FA - Muhletaler, Fred FA - Peabody, James O FA - Diaz-Insua, Mireya FA - Satyanaryana, Ramgopal FA - Menon, Mani IN - Sammon, Jesse D. Vattikuti Urology Institute, Henry Ford Health System, Detroit, Michigan 48202, USA. Jsammon1@hfhs.org TI - Long-term functional urinary outcomes comparing single- vs double-layer urethrovesical anastomosis: two-year follow-up of a two-group parallel randomized controlled trial. CM - Comment in: Urology. 2010 Nov;76(5):1107; author reply 1107-8; PMID: 21056256 SO - Urology. 76(5):1102-7, 2010 Nov AS - Urology. 76(5):1102-7, 2010 Nov NJ - Urology PI - Journal available in: Print PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Anastomosis, Surgical/ae [Adverse Effects] MH - Anastomosis, Surgical/mt [Methods] MH - Humans MH - Male MH - Middle Aged MH - *Prostatectomy/ae [Adverse Effects] MH - Prostatectomy/mt [Methods] MH - *Robotics MH - *Urethra/su [Surgery] MH - *Urinary Bladder/su [Surgery] MH - *Urinary Incontinence/et [Etiology] AB - OBJECTIVES: To evaluate long-term urinary outcomes in participants of a two-group randomized clinical trial comparing continence after robotic prostatectomy (RP) between those who had reconstruction of the rhabdosphincter and puboprostatic collar (double-layer anastomosis) with those who had not. AB - METHODS: Consecutive patients (n = 116) undergoing RP at a single institution were randomized to either single- or double-layer urethrovesical (UV) anastomosis between August and December of 2007. Patients were contacted an average of 23.5 months postoperatively. A survey was performed by a third-party assessor blinded to the intervention, to evaluate urinary outcomes by International Prostate Symptom Score (IPSS), pad usage, and pad weight for those with persistent incontinence. AB - RESULTS: Follow-up at 2 years was 86.5%. There was no statistically significant difference in demographic or preoperative functional variables between groups. There was no difference between groups regarding urine leakage weights, pad usage rates, long-term IPSS score, or IPSS bother score. Both patients in the cohort with incontinence and both with bladder neck contracture (requiring a single dilation) were in the single-layer UV anastomosis group (not significant), yet these patients had not experienced an anastomotic leak at one week. AB - CONCLUSIONS: Long-term functional urinary outcomes were excellent for patients undergoing RP with either single- or double-layer UV anastomosis. IPSS scores and pad usage rates and weights were equivalent between groups. Although patients with single-layer anastomoses were more likely to have a leak at one-week cystogram and longer duration of catheter placement, this did not lead directly to bladder neck contracture or incontinence. AB - Copyright © 2010 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(10)00848-4 DO - https://dx.doi.org/10.1016/j.urology.2010.05.052 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 20869107 [pubmed] ID - S0090-4295(10)00848-4 [pii] ID - 10.1016/j.urology.2010.05.052 [doi] PP - ppublish PH - 2010/02/15 [received] PH - 2010/05/14 [revised] PH - 2010/05/24 [accepted] LG - English DP - 2010 Nov DC - 20101108 EZ - 2010/09/28 06:00 DA - 2010/12/14 06:00 DT - 2010/09/28 06:00 YR - 2010 ED - 20101213 RD - 20101108 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20869107 <434. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20498615 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Truong QA AU - Ptaszek LM AU - Charipar EM AU - Taylor C AU - Fontes JD AU - Kriegel M AU - Irlbeck T AU - Toepker M AU - Schlett CL AU - Bamberg F AU - Blankstein R AU - Brady TJ AU - Nagurney JT AU - Hoffmann U FA - Truong, Quynh A FA - Ptaszek, Leon M FA - Charipar, Elizabeth M FA - Taylor, Carolyn FA - Fontes, Joao D FA - Kriegel, Matthias FA - Irlbeck, Thomas FA - Toepker, Michael FA - Schlett, Christopher L FA - Bamberg, Fabian FA - Blankstein, Ron FA - Brady, Thomas J FA - Nagurney, John T FA - Hoffmann, Udo IN - Truong, Quynh A. Cardiac MR PET CT Program, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA. qtruong@partners.org TI - Performance of electrocardiographic criteria for left ventricular hypertrophy as compared with cardiac computed tomography: from the Rule Out Myocardial Infarction Using Computer Assisted Tomography trial. SO - Journal of Hypertension. 28(9):1959-67, 2010 Sep AS - J Hypertens. 28(9):1959-67, 2010 Sep NJ - Journal of hypertension PI - Journal available in: Print PI - Citation processed from: Internet JC - iew, 8306882 IO - J. Hypertens. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218429 OI - Source: NLM. NIHMS251717 SB - Index Medicus CP - England MH - Adult MH - Aged MH - Cohort Studies MH - Electrocardiography/sn [Statistics & Numerical Data] MH - *Electrocardiography MH - Female MH - Humans MH - *Hypertrophy, Left Ventricular/di [Diagnosis] MH - *Hypertrophy, Left Ventricular/dg [Diagnostic Imaging] MH - Male MH - Middle Aged MH - Myocardial Infarction/di [Diagnosis] MH - Myocardial Infarction/dg [Diagnostic Imaging] MH - Predictive Value of Tests MH - Prospective Studies MH - Tomography, X-Ray Computed/sn [Statistics & Numerical Data] MH - *Tomography, X-Ray Computed AB - OBJECTIVE: Cardiac computed tomography (CT) is a state-of-the-art technology that provides an accurate noninvasive method to quantify left ventricular mass for analysis of left ventricular hypertrophy (LVH). We aimed to examine seven ECG-based LVH criteria against two CT indexation criteria for LVH: a CT-specific body surface area cutoff and the obesity-independent height criteria. AB - METHODS: In 333 patients (mean age 53 +/- 12 years, 61% men), 64-slice contrast-enhanced CT was performed and 12-lead surface ECG within 24 h. Left ventricular mass was measured at end-diastole. Using both CT indexation criteria, the cohort was subdivided into patients with LVH and without LVH. The seven ECG criteria for LVH were the Cornell voltage index, Cornell voltage duration product, Cornell/strain index, Sokolow-Lyon index, Romhilt-Estes scores at least 4 and at least 5, and Gubner-Ungerleider. AB - RESULTS: The ECG parameters had high specificities (85-97%) and variable low sensitivities (4-43%) when compared to either CT criteria of LVH. The three Cornell-based methods performed the best (test-positive likelihood ratio: 4.5-6.7), followed by the Sokolow-Lyon and Romhilt-Estes scores (test-positive likelihood ratio: 2.3-4.0). With the exception of the Gubner-Ungerleider criterion, the other six ECG criteria were associated with at least one of the CT-based LVH (adjusted odds ratio 2.4-9.5) and had incremental predictive value beyond that of hypertension history. AB - CONCLUSION: Using cardiac CT as a gold standard for LVH assessment, ECG criteria for LVH have high specificities with the three Cornell-based criteria providing the best test performance for identifying patients with LVH. ES - 1473-5598 IL - 0263-6352 DO - https://dx.doi.org/10.1097/HJH.0b013e32833b49cb PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't ID - 20498615 [pubmed] ID - 10.1097/HJH.0b013e32833b49cb [doi] ID - PMC3218429 [pmc] ID - NIHMS251717 [mid] PP - ppublish GI - No: T32HL076136 Organization: (HL) *NHLBI NIH HHS* Country: United States No: T32 HL076136 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30HL093896 Organization: (HL) *NHLBI NIH HHS* Country: United States No: R01 HL080053 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30 HL093806-01 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30 HL093806 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K23 HL098370 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English DP - 2010 Sep DC - 20100811 EZ - 2010/05/26 06:00 DA - 2010/12/14 06:00 DT - 2010/05/26 06:00 YR - 2010 ED - 20101207 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20498615 <435. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20629561 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Gundeti MS AU - Wiltz AL AU - Zagaja GP AU - Shalhav AL FA - Gundeti, Mohan S FA - Wiltz, Aimee L FA - Zagaja, Gregory P FA - Shalhav, Arieh L IN - Gundeti, Mohan S. Section of Urology, Department of Surgery, Comer Children's Hospital, University of Chicago Medical Center and Pritzker School of Medicine, Chicago, Illinois 60637, USA. mgundeti@surgery.bsd TI - Robot-assisted laparoscopic intracorporeal hand-sewn bowel anastomosis during pediatric bladder reconstructive surgery. SO - Journal of Endourology. 24(8):1325-8, 2010 Aug AS - J Endourol. 24(8):1325-8, 2010 Aug NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adolescent MH - *Anastomosis, Surgical/mt [Methods] MH - Child MH - Child, Preschool MH - Female MH - Humans MH - *Intestines/su [Surgery] MH - *Laparoscopy/mt [Methods] MH - Male MH - *Reconstructive Surgical Procedures/mt [Methods] MH - *Robotics/mt [Methods] MH - *Suture Techniques MH - *Urinary Bladder/su [Surgery] AB - Bowel anastomosis performed during robot-assisted laparoscopic surgery in both adult and pediatric populations has typically been performed using endoscopic staplers or with exteriorization of the bowel. In the pediatric population, no articles have been published that explore the possibility of a completely intracorporeal hand-sewn anastomosis during robot-assisted laparoscopic surgery. We report our series of six children who were undergoing robot-assisted laparoscopic intracorporeal hand-sewn bowel anastomosis during bladder reconstructive surgery for neurogenic bladder. The postoperative course was uncomplicated with regard to the bowel anastomosis, demonstrating the feasibility of the technique in experienced hands. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2009.0463 PT - Clinical Trial PT - Journal Article ID - 20629561 [pubmed] ID - 10.1089/end.2009.0463 [doi] PP - ppublish LG - English DP - 2010 Aug DC - 20100730 EZ - 2010/07/16 06:00 DA - 2010/11/04 06:00 DT - 2010/07/16 06:00 YR - 2010 ED - 20101103 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20629561 <436. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20092410 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Benson AD AU - Kramer BA AU - Boehler M AU - Schwind CJ AU - Schwartz BF FA - Benson, Aaron D FA - Kramer, Brandan A FA - Boehler, Margaret FA - Schwind, Cathy J FA - Schwartz, Bradley F IN - Benson, Aaron D. Division of Urology, Center for Laparoscopy and Endourology, Southern Illinois University School of Medicine, Springfield, Illinois 62794-9665, USA. TI - Robot-assisted laparoscopic skills development: formal versus informal training. SO - Journal of Endourology. 24(8):1351-5, 2010 Aug AS - J Endourol. 24(8):1351-5, 2010 Aug NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - *Clinical Competence MH - Female MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - *Robotics/ed [Education] MH - *Robotics/is [Instrumentation] MH - Young Adult AB - INTRODUCTION: The learning curve for robotic surgery is not completely defined, and ideal training components have not yet been identified. We attempted to determine whether skill development would be accelerated with formal, organized instruction in robotic surgical techniques versus informal practice alone. AB - MATERIALS AND METHODS: Forty-three medical students naive to robotic surgery were randomized into two groups and tested on three tasks using the robotic platform. Between the testing sessions, the students were given equally timed practice sessions. The formal training group participated in an organized, formal training session with instruction from an attending robotic surgeon, whereas the informal training group participated in an equally timed unstructured practice session with the robot. The results were compared based on technical score and time to completion of each task. AB - RESULTS: There was no difference between groups in prepractice testing for any task. In postpractice testing, there was no difference between groups for the ring transfer tasks. However, for the suture placement and knot-tying task, the technical score of the formal training group was significantly better than that of the informal training group (p < 0.001), yet time to completion was not different. AB - CONCLUSION: Although formal training may not be necessary for basic skills, formal instruction for more advanced skills, such as suture placement and knot tying, is important in developing skills needed for effective robotic surgery. These findings may be important in formulating potential skills labs or training courses for robotic surgery. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2009.0511 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 20092410 [pubmed] ID - 10.1089/end.2009.0511 [doi] PP - ppublish LG - English DP - 2010 Aug DC - 20100730 EZ - 2010/01/23 06:00 DA - 2010/11/04 06:00 DT - 2010/01/23 06:00 YR - 2010 ED - 20101103 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20092410 <437. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20375930 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Walker J AU - Fairley CK AU - Walker SM AU - Gurrin LC AU - Gunn JM AU - Pirotta MV AU - Carter R AU - Hocking JS FA - Walker, Jennifer FA - Fairley, Christopher K FA - Walker, Sandra M FA - Gurrin, Lyle C FA - Gunn, Jane M FA - Pirotta, Marie V FA - Carter, Rob FA - Hocking, Jane S IN - Walker, Jennifer. University of Melbourne, Victoria, Australia. walker@unimelb.edu.au TI - Computer reminders for Chlamydia screening in general practice: a randomized controlled trial. SO - Sexually Transmitted Diseases. 37(7):445-50, 2010 Jul AS - Sex Transm Dis. 37(7):445-50, 2010 Jul NJ - Sexually transmitted diseases PI - Journal available in: Print PI - Citation processed from: Internet JC - u9g, 7705941 IO - Sex Transm Dis SB - Index Medicus CP - United States MH - Adolescent MH - Adult MH - Australia/ep [Epidemiology] MH - Chlamydia MH - *Chlamydia Infections/di [Diagnosis] MH - Chlamydia Infections/ep [Epidemiology] MH - *Family Practice MH - Female MH - Guideline Adherence MH - Humans MH - Male MH - Mass Screening/mt [Methods] MH - *Mass Screening/sn [Statistics & Numerical Data] MH - *Medical Records Systems, Computerized MH - Middle Aged MH - Physicians, Family MH - *Reminder Systems MH - *Software MH - Young Adult AB - BACKGROUND: Chlamydia notifications are increasing in Australia, and the use of a computer alert prompting general practitioners to test young women is a potential way to increase opportunistic chlamydia testing. The aim of this trial was to determine the effectiveness of a computer alert in general practice on chlamydia testing in young women. AB - METHODS: In 2006, clinics (n = 68) in Melbourne, Australia were cluster randomized into 2 groups: the intervention group received a computerized alert advising the general practitioner to discuss chlamydia testing with their patient which popped up when the medical record of a 16- to 24-year-old woman was opened; the control group received no alert. The outcome was whether or not that patient received a chlamydia test at the level of a single consultation with an eligible patient. A mixed effects logistic regression model adjusting for clustering was used to assess the impact of the alert on the proportion of women tested for chlamydia during the trial period. AB - RESULTS: Testing increased from 8.3% (95% confidence interval (CI): 6.8, 9.8) to 12.2% (95% CI: 9.1, 15.3) (P < 0.01) in the intervention group, and from 8.8% (95% CI: 6.8, 10.7) to 10.6% (95% CI: 8.5, 12.7) (P < 0.01) in the control group. Overall, the intervention group had a 27% (OR = 1.3; 95% CI: 1.1, 1.4) greater increase in testing. AB - CONCLUSION: The results of this study suggest that alerts alone may not be sufficient to get chlamydia testing levels up sufficiently high enough to have an impact on the burden of chlamydia in the population but that they could be included as part of a more complex intervention. ES - 1537-4521 IL - 0148-5717 DO - https://dx.doi.org/10.1097/OLQ.0b013e3181cfcb4c PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 20375930 [pubmed] ID - 10.1097/OLQ.0b013e3181cfcb4c [doi] PP - ppublish LG - English DP - 2010 Jul DC - 20100623 EZ - 2010/04/09 06:00 DA - 2010/10/15 06:00 DT - 2010/04/09 06:00 YR - 2010 ED - 20101014 RD - 20100623 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20375930 <438. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20459328 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Buchs NC AU - Bucher P AU - Pugin F AU - Hagen ME AU - Morel P FA - Buchs, Nicolas C FA - Bucher, Pascal FA - Pugin, Francois FA - Hagen, Monika E FA - Morel, Philippe IN - Buchs, Nicolas C. Department of Surgery, University Hospital Geneva, Geneva, Switzerland. nicolas.c.buchs@hcuge.ch TI - Robot-assisted oncologic resection for large gastric gastrointestinal stromal tumor: a preliminary case series. SO - Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A. 20(5):411-5, 2010 Jun AS - J Laparoendosc Adv Surg Tech A. 20(5):411-5, 2010 Jun NJ - Journal of laparoendoscopic & advanced surgical techniques. Part A PI - Journal available in: Print PI - Citation processed from: Internet JC - 9706293, c0d IO - J Laparoendosc Adv Surg Tech A SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Female MH - *Gastrectomy/is [Instrumentation] MH - Gastrectomy/mt [Methods] MH - *Gastrointestinal Stromal Tumors/su [Surgery] MH - Humans MH - Laparoscopy MH - Male MH - Middle Aged MH - Prospective Studies MH - Robotics MH - *Stomach Neoplasms/su [Surgery] MH - Treatment Outcome AB - BACKGROUND: Laparoscopic resection of gastric gastrointestinal stromal tumor (GIST) has been shown as feasible and safe in terms of oncologic results. However, laparoscopic resection has been demonstrated to be mainly suitable for small, favorably localized GIST. The robotic approach may, by its characteristics, enable the surgeon to perform atypical gastrectomies in an unfavorable location (i.e., close to pylorus or cardia). Its use in oncologic gastric surgery has been poorly defined and has never been reported for GIST. AB - MATERIALS AND METHODS: All patients who underwent robotic-assisted gastric resection for GIST at a single institution from 2006 to 2009 were prospectively followed-up. AB - RESULTS: There were 5 patients (3 men and 2 women), with a median age of 39 years (range, 32-74), who had a complete resection (R0). Two patients had a cardial GIST and 3 of the antrum. Median tumor sizes were of 5.5 cm (range, 4.2-7). According to Fletcher criteria, 4 tumors (80%) were classified as intermediate or high risk. No postoperative morbidity and mortality were noted. One patient had a conversion to open surgery because of a suspicion of diffuse adenocarcinoma on fresh frozen section and necessitated a total gastrectomy with a radical lymph node dissection. Median operation time was 192 minutes (range, 132-285). With a median follow-up of 18 months (range, 11-27), disease-free survival rate was 100%. AB - CONCLUSIONS: The da Vinci robot (Intuitive Surgical, Inc., Sunnyvale, CA) is a valuable instrument for oncologically safe resection with esogastric or duodenogastric junction preservation for an unfavorably located gastric GIST. Moreover, the three-dimensional, high-definition vision, instrument mobility, and ease of performing a difficult suturing enable a safe, large atypical gastrectomy, close to the pylorus or cardia. ES - 1557-9034 IL - 1092-6429 DO - https://dx.doi.org/10.1089/lap.2009.0385 PT - Clinical Trial PT - Journal Article ID - 20459328 [pubmed] ID - 10.1089/lap.2009.0385 [doi] PP - ppublish LG - English DP - 2010 Jun DC - 20100622 EZ - 2010/05/13 06:00 DA - 2010/10/12 06:00 DT - 2010/05/13 06:00 YR - 2010 ED - 20101007 RD - 20100622 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20459328 <439. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20646744 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Haber GP AU - White WM AU - Crouzet S AU - White MA AU - Forest S AU - Autorino R AU - Kaouk JH FA - Haber, Georges-Pascal FA - White, Wesley M FA - Crouzet, Sebastien FA - White, Michael A FA - Forest, Sylvain FA - Autorino, Riccardo FA - Kaouk, Jihad H IN - Haber, Georges-Pascal. Section of Laparoscopic and Robotic Urologic Surgery, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA. TI - Robotic versus laparoscopic partial nephrectomy: single-surgeon matched cohort study of 150 patients. SO - Urology. 76(3):754-8, 2010 Sep AS - Urology. 76(3):754-8, 2010 Sep NJ - Urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Cohort Studies MH - Female MH - Humans MH - *Kidney Neoplasms/su [Surgery] MH - *Laparoscopy MH - Male MH - Middle Aged MH - *Nephrectomy/mt [Methods] MH - Retrospective Studies MH - *Robotics AB - OBJECTIVES: To present comparative outcomes among matched patients who underwent robotic partial nephrectomy (RPN) or laparoscopic partial nephrectomy (LPN) by a single surgeon at a single institution. AB - METHODS: Between March 2002 and August 2009, a retrospective review of 261 consecutive patients who underwent LPN (n = 186) or RPN (n = 75) by a single surgeon was performed. Patients were matched for age, gender, body mass index (BMI), American Society of Anesthesiologists (ASA) score, and tumor size, side, and location. Perioperative outcomes were compared. AB - RESULTS: A matched cohort of 150 patients who underwent RPN (n = 75) or LPN (n = 75) were compared. There was no significant difference between the 2 cohorts with respect to patient age (P = .17), BMI (P = .68), ASA score (P = .96), preoperative estimated glomerulofiltration rate (eGFR; P = .54), or tumor size (P = .17). Mean operative time for RPN was 200 vs 197 minutes for LPN (P = .75). Mean estimated blood loss (EBL) was higher in the RPN cohort (323 vs 222 mL, P = .01). There was no significant difference with respect to warm ischemia time (18.2 minutes vs 20.3 minutes, P = .27), length of hospitalization (P = .84), percent change in eGFR (P = .80), or adverse events (P = .52). All surgical margins were negative. AB - CONCLUSIONS: Although initial surgical experience with RPN was included in this study and compared with a vast experience in LPN by the same surgeon, RPN offers at least comparable outcomes to LPN. AB - Copyright © 2010 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(10)00477-2 DO - https://dx.doi.org/10.1016/j.urology.2010.03.058 PT - Comparative Study PT - Journal Article ID - 20646744 [pubmed] ID - S0090-4295(10)00477-2 [pii] ID - 10.1016/j.urology.2010.03.058 [doi] PP - ppublish PH - 2010/01/05 [received] PH - 2010/03/18 [revised] PH - 2010/03/21 [accepted] LG - English EP - 20100619 DP - 2010 Sep DC - 20100913 EZ - 2010/07/22 06:00 DA - 2010/10/05 06:00 DT - 2010/07/22 06:00 YR - 2010 ED - 20101004 RD - 20100913 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20646744 <440. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20491593 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Gupta NP AU - Nayyar R AU - Singh P AU - Anand A FA - Gupta, Narmada P FA - Nayyar, Rishi FA - Singh, Prabhjot FA - Anand, Ajay IN - Gupta, Narmada P. Department of Urology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India. narmadagupta@hotmail.com TI - Robot-assisted adrenal-sparing surgery for pheochromocytoma: initial experience. SO - Journal of Endourology. 24(6):981-5, 2010 Jun AS - J Endourol. 24(6):981-5, 2010 Jun NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - *Adrenal Gland Neoplasms/su [Surgery] MH - Adrenal Glands/pa [Pathology] MH - *Adrenal Glands/su [Surgery] MH - Adult MH - Female MH - Humans MH - Male MH - Perioperative Care MH - *Pheochromocytoma/su [Surgery] MH - *Robotics/mt [Methods] MH - Tomography, X-Ray Computed AB - PURPOSE: To assess the feasibility, describe the technique, and report our experience with use of the da Vinci S robotic surgical system in the management of pheochromocytoma. AB - PATIENTS AND METHODS: For four patients with metabolically active adrenal pheochromocytoma (two right, two left), standard preoperative preparation was performed. A robotic transperitoneal approach was used for all cases. Sparing of the adjacent normal parenchyma was performed in all cases. All relevant perioperative details were collected and analyzed. AB - RESULTS: Mean operative time was 77.5 minutes (range 40-140 min), and blood loss was 97.5 mL (range 50-160 mL). There were no conversions or perioperative complications. Average tumor size was 4.7 cm. There were three episodes of intraoperative hypertension necessitating therapeutic intervention. Average analgesic requirement was 150 mg of diclofenac, and patients were allowed oral intake after 6 hours. The drain was removed within 24 hours, with average hospital stay of 4 days. The histopathology report confirmed pheochromocytoma in all patients with free surgical resection margins. Average follow-up was 9 months (range 4-14 mos) with no evidence of recurrence or extra-adrenal tumor. AB - CONCLUSION: Robot-assisted excision of pheochromocytoma is feasible, safe, and efficacious in our early experience. Sparing of the normal adjacent adrenal parenchyma is possible with little detrimental effect on the oncologic efficacy of the surgery. Long-term studies are needed to further confirm this issue. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2009.0351 PT - Clinical Trial PT - Journal Article ID - 20491593 [pubmed] ID - 10.1089/end.2009.0351 [doi] PP - ppublish LG - English DP - 2010 Jun DC - 20100610 EZ - 2010/05/25 06:00 DA - 2010/09/16 06:00 DT - 2010/05/25 06:00 YR - 2010 ED - 20100915 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20491593 <441. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20685519 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Liu H AU - Liu DX AU - Wang G AU - Wang CL AU - Zhao Z FA - Liu, Hong FA - Liu, Dong-xu FA - Wang, Guangchun FA - Wang, Chun-ling FA - Zhao, Zhen IN - Liu, Hong. Department of Orthodontics, Shandong University, Jinan, China. TI - Accuracy of surgical positioning of orthodontic miniscrews with a computer-aided design and manufacturing template. SO - American Journal of Orthodontics & Dentofacial Orthopedics. 137(6):728.e1-728.e10; discussion 728-9, 2010 Jun AS - Am J Orthod Dentofacial Orthop. 137(6):728.e1-728.e10; discussion 728-9, 2010 Jun NJ - American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics PI - Journal available in: Print PI - Citation processed from: Internet JC - 3fw, 8610224 IO - Am J Orthod Dentofacial Orthop SB - Dental Journals SB - Index Medicus CP - United States MH - Bone Screws MH - Computer Simulation MH - *Computer-Aided Design MH - Equipment Design MH - Humans MH - Incisor/pa [Pathology] MH - Jaw/dg [Diagnostic Imaging] MH - Models, Anatomic MH - *Orthodontic Anchorage Procedures/is [Instrumentation] MH - *Orthodontic Anchorage Procedures/mt [Methods] MH - Software Validation MH - *Surgery, Computer-Assisted MH - Tomography, X-Ray Computed MH - User-Computer Interface AB - INTRODUCTION: Our objective was to enable accurate miniscrew placement after preoperative simulation. We developed a new template for miniscrew placement and evaluated its accuracy. AB - METHODS: Eleven patients who had bimaxillary protrusion were scanned with computed tomography. The 3-dimensional computed tomography data were used to produce, with stereolithography apparatus, a template for accurate miniscrew placement. The interradicular space available for miniscrew placement was calculated in the 3-dimensional images. Postoperative computed tomography images were matched with preoperative images to calculate the deviations between the planned and actual placements. AB - RESULTS: The distance for placement of a miniscrew between 2 roots was 4.12 mm (SD, 0.25 mm; range, 3.7-4.5 mm). The placed miniscrews showed an average angular deviation of 1.2 degrees (SD, 0.43 degrees ; range, 0.6 degrees -2.41 degrees ) compared with the plan, whereas the mean linear distomesial deviation was 0.42 mm (SD, 0.13 mm; range, 0.15-0.6 mm) at the tip. AB - CONCLUSIONS: The proposed template has high accuracy and will be especially useful for patients who require precise miniscrew placement. AB - Copyright 2010 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved. ES - 1097-6752 IL - 0889-5406 DI - S0889-5406(10)00188-5 DO - https://dx.doi.org/10.1016/j.ajodo.2009.12.025 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 20685519 [pubmed] ID - S0889-5406(10)00188-5 [pii] ID - 10.1016/j.ajodo.2009.12.025 [doi] PP - ppublish PH - 2009/10/01 [received] PH - 2009/12/01 [revised] PH - 2009/12/01 [accepted] LG - English DP - 2010 Jun DC - 20100805 EZ - 2010/08/06 06:00 DA - 2010/08/24 06:00 DT - 2010/08/06 06:00 YR - 2010 ED - 20100823 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20685519 <442. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19570067 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ballal MS AU - Selvachandran SN AU - Maw A FA - Ballal, M S FA - Selvachandran, S N FA - Maw, A IN - Ballal, M S. Department of Surgery, Leighton Research Unit, Mid Cheshire NHS trust, Middlewhich Road, Crewe, CW1 4QJ, UK. TI - Use of a patient consultation questionnaire and weighted numerical scoring system for the prediction of colorectal cancer and other colorectal pathology in symptomatic patients: a prospective cohort validation study of a Welsh population. SO - Colorectal Disease. 12(5):407-14, 2010 May AS - Colorectal Dis. 12(5):407-14, 2010 May NJ - Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 100883611 IO - Colorectal Dis SB - Index Medicus CP - England MH - Adult MH - Aged MH - Aged, 80 and over MH - Carcinoma, Squamous Cell/di [Diagnosis] MH - *Colorectal Neoplasms/di [Diagnosis] MH - England MH - Female MH - Humans MH - Male MH - Middle Aged MH - Practice Guidelines as Topic/st [Standards] MH - Prospective Studies MH - ROC Curve MH - Referral and Consultation/cl [Classification] MH - *Referral and Consultation/st [Standards] MH - Risk Assessment MH - Sensitivity and Specificity MH - Surveys and Questionnaires/st [Standards] MH - *Surveys and Questionnaires MH - *Triage/mt [Methods] MH - Wales AB - OBJECTIVE: There is currently no system in widespread use that accurately prioritizes colorectal referrals in symptomatic patients with an acceptable degree of sensitivity and specificity. We have validated a weighted numerical scoring system for the prioritization of such colorectal referrals in an attempt to rectify this, with detection of colorectal cancer (CRC) the primary outcome. AB - METHOD: We conducted a prospective study of symptomatic patients referred by primary care to the colorectal service in a district general hospital. A computer-generated weighted numerical score (WNS) was derived from the primary symptoms and symptom combinations. Patients underwent colorectal investigations and a final diagnosis was established. Sensitivity, specificity and accuracy of CRC detection as determined by the WNS, Department of Health (DOH) and National Institute for Health and Clinical Excellence guidelines was determined. Primary Care compliance with guidelines was analysed. AB - RESULTS: A definitive diagnosis was established in 3457 patients. One hundred and eighty-six (5.4%) had CRC. The mean score for the cancer patients (76.9, 95%CI 72-81) was significantly higher than that of non-cancer patients (52, 95%CI 52-53) P < 0.001. Receiver Operator Curve analysis demonstrates a high discriminatory power for the Patient Consultation Questionnaire (PCQ) with an area under curve of 0.76. Compliance by primary care with the nationally recommended referral guidelines was poor with only 55% and 58% compliance with DOH and National Institute for Clinical Excellence referral guidelines for suspected cancer respectively. AB - CONCLUSION: The PCQ and the WNS is an efficient, objective system that allows the accurate prioritization of colorectal referrals with a high sensitivity for cancer and other serious colorectal pathologies. ES - 1463-1318 IL - 1462-8910 DI - CDI1984 DO - https://dx.doi.org/10.1111/j.1463-1318.2009.01984.x PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Validation Studies ID - 19570067 [pubmed] ID - CDI1984 [pii] ID - 10.1111/j.1463-1318.2009.01984.x [doi] PP - ppublish LG - English EP - 20090630 DP - 2010 May DC - 20100507 EZ - 2009/07/03 09:00 DA - 2010/08/11 06:00 DT - 2009/07/03 09:00 YR - 2010 ED - 20100810 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19570067 <443. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20409226 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Jeong W AU - Araki M AU - Park SY AU - Lee YH AU - Kumon H AU - Hong SJ AU - Rha KH FA - Jeong, Wooju FA - Araki, Motoo FA - Park, Sung Yul FA - Lee, Young Hoon FA - Kumon, Hiromi FA - Hong, Sung Joon FA - Rha, Koon Ho IN - Jeong, Wooju. Departments of Urology and Urological Science Institute,Yonsei University College of Medicine, Seoul, Korea. TI - Robot-assisted laparoscopic radical prostatectomy in the Asian population: modified port configuration and ultradissection. SO - International Journal of Urology. 17(3):297-300, 2010 Mar AS - Int J Urol. 17(3):297-300, 2010 Mar NJ - International journal of urology : official journal of the Japanese Urological Association PI - Journal available in: Print PI - Citation processed from: Internet JC - ce6, 9440237 IO - Int. J. Urol. SB - Index Medicus CP - Australia MH - Aged MH - *Asian Continental Ancestry Group MH - Dissection/mt [Methods] MH - Humans MH - Japan MH - *Laparoscopy MH - Male MH - Pelvis/ah [Anatomy & Histology] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotics MH - Severity of Illness Index AB - We have carried out over 360 cases of robot-assisted laparoscopic radical prostatectomy (RARP) to date. In the present study, we detail our current technique at Yonsei University College of Medicine. The six-port transperitoneal approach is utilized. The most lateral two ports were placed medially and caudally in patients with a small pelvis to avoid interference between the ports and the pelvis (modified port configuration). Lymph node dissection is carried out in the external iliac, obturator and infraobturator area. The dissection on the lateral border of the bladder neck is carried out until it reaches the seminal vesicle (ultradissection). After transection of the bladder neck, vasa seminal vesicles are dissected further. Neurovascular bundles are preserved in selected patients. The dorsal venous complex (DVC) and the urethra are transected without suturing. Urethrovesical anastomosis is carried out with 3-0 monocryl running suture, incorporating with the edge of DVC. The puboprostatic collar and bladder are incorporated by 3-0 monocryl running suture (puboperineoplasty). Between November 2007 and September 2008, RARP was carried out using this technique in 182 patients. Median height, weight, body mass index and prostate-specific antigen (PSA) were 168 cm, 68 kg, 24 kg/M(2) and 7.1 ng/mL, respectively. Mean operative time was 192 min and average blood loss was 250 mL. Median catheterization time was 8 days. Positive surgical margin rates for pT2, pT3 and pT4 disease was 12.7, 48 and 100%, respectively. Intraoperative complication rate was 2.7%. Fifty-five patients completed a minimum of 10 months follow up. Their continence rate was 91%. RARP is a safe and feasible surgical modality for prostate cancer among Asian patients with a small pelvis. Our technique achieves a precise bladder neck dissection. ES - 1442-2042 IL - 0919-8172 DI - IJU2480 DO - https://dx.doi.org/10.1111/j.1442-2042.2010.02480.x PT - Clinical Trial PT - Journal Article ID - 20409226 [pubmed] ID - IJU2480 [pii] ID - 10.1111/j.1442-2042.2010.02480.x [doi] PP - ppublish LG - English DP - 2010 Mar DC - 20100422 EZ - 2010/04/23 06:00 DA - 2010/07/16 06:00 DT - 2010/04/23 06:00 YR - 2010 ED - 20100715 RD - 20100422 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20409226 <444. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20136397 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Xylinas E AU - Ploussard G AU - Salomon L AU - Paul A AU - Gillion N AU - Laet KD AU - Vordos D AU - Hoznek A AU - Abbou CC AU - de la Taille A FA - Xylinas, Evanguelos FA - Ploussard, Guillaume FA - Salomon, Laurent FA - Paul, Alexandre FA - Gillion, Norman FA - Laet, Kevin De FA - Vordos, Dimitri FA - Hoznek, Andras FA - Abbou, Clement-Claude FA - de la Taille, Alexandre IN - Xylinas, Evanguelos. Department of Urology, Henri Mondor Hospital, Creteil, France. TI - Intrafascial nerve-sparing radical prostatectomy with a laparoscopic robot-assisted extraperitoneal approach: early oncological and functional results. SO - Journal of Endourology. 24(4):577-82, 2010 Apr AS - J Endourol. 24(4):577-82, 2010 Apr NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Aged MH - Dissection MH - Humans MH - *Laparoscopy MH - Male MH - Middle Aged MH - Penile Erection/ph [Physiology] MH - Perioperative Care MH - *Peritoneum/su [Surgery] MH - *Prostate/ir [Innervation] MH - Prostate/pa [Pathology] MH - Prostate/pp [Physiopathology] MH - *Prostate/su [Surgery] MH - *Prostatectomy/mt [Methods] MH - Quality of Life MH - *Robotics/mt [Methods] MH - Treatment Outcome MH - Urinary Bladder/su [Surgery] AB - OBJECTIVE: We investigated whether an intrafascial approach to prostatectomy would provide significantly improved outcomes compared with retropubic and laparoscopic approaches. We performed 50 radical prostatectomies with an intrafascial, nerve-sparing, laparoscopic, robot-assisted extraperitoneal approach. AB - METHODS: From December 2007 to June 2008, 50 consecutive patients underwent nerve sparing surgery using the intrafascial technique with robotic assistance. All surgeries were performed by the same senior urologist. Patient characteristics and perioperative data were collected prospectively. Oncological outcomes were assessed by pathological examination and postoperative prostate-specific antigen levels. Functional outcomes, including continence, potency, and quality of life, were assessed from patient questionnaires. AB - RESULTS: The mean operative time was 127 minutes (range: 80-205), the mean hospital stay was 4.2 days (range: 2-9), and the mean catheterization time was 7.8 days (range: 4-11). No perioperative complications occurred. One patient required a transfusion at the postoperative stage. The overall positive surgical margin rate was 12%; adjusted by tumor, nodes, and metastasis stage, it was 9.5% in pT2 and 17% in pT3 disease. At the 1-month follow-up, 66% of the patients were continent (no pad), 12% presented a minimal stress urinary incontinence (1 pad), and 22% required >1 pad(s) per day. Further, 60% of patients exhibited potency (erection sufficient for intercourse: 30% without the use of phosphodiesterase 5 inhibitors, 30% required a phosphodiesterase 5 inhibitor) and the remaining 40% required prostaglandin injections. AB - CONCLUSIONS: An intrafascial approach with robotic assistance provided satisfactory early functional results with respect to postoperative continence and potency. Long-term oncological results remain to be assessed. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2009.0069 PT - Clinical Trial PT - Journal Article ID - 20136397 [pubmed] ID - 10.1089/end.2009.0069 [doi] PP - ppublish LG - English DP - 2010 Apr DC - 20100428 EZ - 2010/02/09 06:00 DA - 2010/07/16 06:00 DT - 2010/02/09 06:00 YR - 2010 ED - 20100715 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20136397 <445. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20334556 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Wu SD AU - Viprakasit DP AU - Cashy J AU - Smith ND AU - Perry KT AU - Nadler RB FA - Wu, Simon D FA - Viprakasit, Davis P FA - Cashy, John FA - Smith, Norm D FA - Perry, Kent T FA - Nadler, Robert B IN - Wu, Simon D. Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA. TI - Radiofrequency ablation-assisted robotic laparoscopic partial nephrectomy without renal hilar vessel clamping versus laparoscopic partial nephrectomy: a comparison of perioperative outcomes. SO - Journal of Endourology. 24(3):385-91, 2010 Mar AS - J Endourol. 24(3):385-91, 2010 Mar NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Catheter Ablation/ae [Adverse Effects] MH - *Catheter Ablation/mt [Methods] MH - Constriction MH - Female MH - Humans MH - *Kidney/bs [Blood Supply] MH - *Kidney/su [Surgery] MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy MH - Linear Models MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Nephrectomy/ae [Adverse Effects] MH - *Nephrectomy/mt [Methods] MH - *Perioperative Care MH - Postoperative Complications/et [Etiology] MH - *Robotics/mt [Methods] MH - Treatment Outcome AB - OBJECTIVES: Radiofrequency ablation (RFA)-assisted laparoscopic partial nephrectomy (LPN) may allow for improved hemostasis without need for renal hilar vessel clamping and elimination of warm ischemia to the kidney. We compare outcomes in patients undergoing radiofrequency ablation-assisted robotic clampless partial nephrectomy (RF-RCPN) and LPN. AB - METHODS: Thirty-six patients and 42 patients underwent LPN and RF-RCPN, respectively. In the RF-RCPN group, the Habib 4x RFA device was used to coagulate a margin of normal parenchyma around the renal mass to allow excision of the mass within a bloodless plane. Unlike in the LPN group, renal hilar vascular occlusion was not performed in the RF-RCPN group. AB - RESULTS: Tumors treated in the RF-RCPN group tended to be larger (2.8 vs. 2.0 cm) and more often endophytic (52.6% vs. 16.1%). Collecting system reconstruction occurred more often in the RF-RCPN group (78.6% vs. 30.6%). Operative duration was longer in the RF-RCPN group (373 vs. 250 minutes), but this included time for cystoscopy, ureteral stenting, and repositioning of the patient. Blood loss, transfusion rates, renal function, and complication rates did not differ between the two groups. No patients required renal hilar vessel clamping or nephrectomy to control bleeding in the RF-RCPN group. AB - CONCLUSIONS: The use of RFA-assistance during robotic partial nephrectomy allows excision of renal tumors without hilar vascular clamping, thus eliminating renal warm ischemia. Larger and more centrally located tumors were excised with RF-RCPN. No differences in blood loss, complication rate, postoperative bleeding, renal function, or recurrence rate were noted compared with LPN. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2009.0199 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 20334556 [pubmed] ID - 10.1089/end.2009.0199 [doi] PP - ppublish LG - English DP - 2010 Mar DC - 20100325 EZ - 2010/03/26 06:00 DA - 2010/07/01 06:00 DT - 2010/03/26 06:00 YR - 2010 ED - 20100630 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20334556 <446. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19958072 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Koliakos N AU - Mottrie A AU - Buffi N AU - De Naeyer G AU - Willemsen P AU - Fonteyne E FA - Koliakos, Nikolaos FA - Mottrie, Alexandre FA - Buffi, Nicolo FA - De Naeyer, Geert FA - Willemsen, Pieter FA - Fonteyne, Etienne IN - Koliakos, Nikolaos. Urology Clinic, OLV Hospital, Aalst, Belgium. TI - Posterior and anterior fixation of the urethra during robotic prostatectomy improves early continence rates. SO - Scandinavian Journal of Urology & Nephrology. 44(1):5-10, 2010 Feb AS - Scand J Urol Nephrol. 44(1):5-10, 2010 Feb NJ - Scandinavian journal of urology and nephrology PI - Journal available in: Print PI - Citation processed from: Internet JC - uda, 0114501 IO - Scand. J. Urol. Nephrol. SB - Index Medicus CP - England MH - Aged MH - Anastomosis, Surgical MH - Humans MH - Male MH - Middle Aged MH - Prospective Studies MH - Prostatectomy/mt [Methods] MH - *Prostatectomy MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotics MH - Single-Blind Method MH - *Urethra/su [Surgery] MH - *Urinary Bladder/su [Surgery] MH - *Urinary Incontinence/pc [Prevention & Control] AB - OBJECTIVE: To investigate whether posterior and anterior fixation of the vesicourethral anastomosis during robotic radical prostatectomy (RRP) helps to establish continence earlier. AB - MATERIAL AND METHODS: Forty-seven consecutive patients undergoing RRP were randomized into two groups. The first group received a typical Van Velthoven vesicourethral anastomosis and the second group a modified anastomosis with posterior and anterior fixation. In this group the posterior fibrous tissues of the sphincter were sutured to the residual Denonvilliers' fascia. The anastomosis with two running sutures started at the 6 o'clock position on the bladder neck and continued upwards. Two-step stitching was done on the upper half of the anastomosis to ensure good stabilization of the bladder: a small portion of urethral stump followed by a deep haemostatic stitch on the plexus. Continence, as measured by patient self-reporting of the number of pads used per 24 h, was assessed 7 weeks after catheter removal, by telephone interview. The use of no pads or one pad was defined as "continent", two pads as "moderate incontinence" and more than two pads as "severe incontinence". AB - RESULTS: At catheter removal, more patients in the fixation group were continent than in the Van Velthoven group [9/23 (39%) vs 3/24 (12.5%), p = 0.036]. At 7 weeks, continence was even better in the fixation group [15/23 (65%) vs 8/24 (33%), p = 0. 029]. The mean pad usage was less in the fixation group (1.43 vs 2.25, p = 0.032). AB - CONCLUSIONS: The posterior and anterior fixation of the vesicourethral anastomosis during RRP results in an intact sphincteric mechanism, because no stretch is applied to the urethra, resulting in earlier continence. ES - 1651-2065 IL - 0036-5599 DO - https://dx.doi.org/10.3109/00365590903413627 PT - Journal Article PT - Randomized Controlled Trial ID - 19958072 [pubmed] ID - 10.3109/00365590903413627 [doi] PP - ppublish LG - English DP - 2010 Feb DC - 20100204 EZ - 2009/12/05 06:00 DA - 2010/06/23 06:00 DT - 2009/12/05 06:00 YR - 2010 ED - 20100622 RD - 20100204 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19958072 <447. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19853987 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Nix J AU - Smith A AU - Kurpad R AU - Nielsen ME AU - Wallen EM AU - Pruthi RS FA - Nix, Jeff FA - Smith, Angela FA - Kurpad, Raj FA - Nielsen, Matthew E FA - Wallen, Eric M FA - Pruthi, Raj S IN - Nix, Jeff. Division of Urologic Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. TI - Prospective randomized controlled trial of robotic versus open radical cystectomy for bladder cancer: perioperative and pathologic results. CM - Comment in: Eur Urol. 2010 Feb;57(2):202-3; author reply 203-4; PMID: 19931975 SO - European Urology. 57(2):196-201, 2010 Feb AS - Eur Urol. 57(2):196-201, 2010 Feb NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Adult MH - Aged MH - Aged, 80 and over MH - *Cystectomy/mt [Methods] MH - Female MH - Humans MH - Male MH - Middle Aged MH - Prospective Studies MH - *Robotics MH - Treatment Outcome MH - *Urinary Bladder Neoplasms/pa [Pathology] MH - *Urinary Bladder Neoplasms/su [Surgery] AB - BACKGROUND: In recent years, surgeons have begun to report case series of minimally invasive approaches to radical cystectomy, including robotic-assisted techniques demonstrating the surgical feasibility of this procedure with the potential of lower blood loss and more rapid return of bowel function and hospital discharge. Despite these experiences and observations, at this point high levels of clinical evidence with regard to the benefits of robotic cystectomy are absent, and the current experiences represent case series with limited comparisons to historical controls at best. AB - OBJECTIVE: We report our results on a prospective randomized trial of open versus robotic-assisted laparoscopic radical cystectomy with regard to perioperative outcomes, complications, and short-term narcotic usage. AB - DESIGN, SETTING, AND PARTICIPANTS: A prospective randomized single-center noninferiority study comparing open versus robotic approaches to cystectomy in patients who are candidates for radical cystectomy for urothelial carcinoma of the bladder. Of the 41 patients who underwent surgery, 21 were randomized to the robotic approach and 20 to the open technique. AB - INTERVENTION: Radical cystectomy, bilateral pelvic lymphadenectomy, and urinary diversion by either an open approach or by a robotic-assisted laparoscopic technique. AB - MEASUREMENTS: The primary end point was lymph node (LN) yield with a noninferiority margin of four LNs. Secondary end points included demographic characteristics, perioperative outcomes, pathologic results, and short-term narcotic use. AB - RESULTS AND LIMITATIONS: On univariate analysis, no significant differences were found between the two groups with regard to age, sex, body mass index, American Society of Anesthesiologists classification, anticoagulation regimen of aspirin, clinical stage, or diversion type. Significant differences were noted in operating room time, estimated blood loss, time to flatus, time to bowel movement, and use of inpatient morphine sulfate equivalents. There was no significant difference in regard to overall complication rate or hospital stay. On surgical pathology, in the robotic group 14 patients had pT2 disease or higher; 3 patients had pT3/T4 disease; and 4 patients had node-positive disease. In the open group, eight patients had pT2 disease or higher; five patients had pT3/T4 disease; and seven patients had node-positive disease. The mean number of LNs removed was 19 in the robotic group versus18 in the open group. Potential study limitations include the limited clinical and oncologic follow-up and the relatively small and single-institution nature of the study. AB - CONCLUSIONS: We present the results of a prospective randomized controlled noninferiority study with a primary end point of LN yield, demonstrating the robotic approach to be noninferior to the open approach. The robotic approach also compares favorably with the open approach in several perioperative parameters. AB - Copyright 2009 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(09)01028-8 DO - https://dx.doi.org/10.1016/j.eururo.2009.10.024 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 19853987 [pubmed] ID - S0302-2838(09)01028-8 [pii] ID - 10.1016/j.eururo.2009.10.024 [doi] PP - ppublish PH - 2009/08/03 [received] PH - 2009/10/13 [accepted] LG - English EP - 20091020 DP - 2010 Feb DC - 20100201 EZ - 2009/10/27 06:00 DA - 2010/05/21 06:00 DT - 2009/10/27 06:00 YR - 2010 ED - 20100519 RD - 20100201 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19853987 <448. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19097718 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Nemec SF AU - Peloschek P AU - Schmook MT AU - Krestan CR AU - Hauff W AU - Matula C AU - Czerny C FA - Nemec, Stefan Franz FA - Peloschek, Philipp FA - Schmook, Maria Theresa FA - Krestan, Christian Robert FA - Hauff, Wolfgang FA - Matula, Christian FA - Czerny, Christian IN - Nemec, Stefan Franz. Department of Radiology/Division of Neuroradiology and Musculoskeletal Radiology, Medical University Vienna, Waehringerguertel 18-20, A-1090 Vienna, Austria. stefan.nemec@meduniwien.ac.at TI - CT-MR image data fusion for computer-assisted navigated surgery of orbital tumors. SO - European Journal of Radiology. 73(2):224-9, 2010 Feb AS - Eur J Radiol. 73(2):224-9, 2010 Feb NJ - European journal of radiology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - em6, 8106411 IO - Eur J Radiol SB - Index Medicus CP - Ireland MH - Adult MH - Aged MH - Female MH - Humans MH - *Magnetic Resonance Imaging/mt [Methods] MH - Male MH - Middle Aged MH - *Orbital Neoplasms/di [Diagnosis] MH - *Orbital Neoplasms/su [Surgery] MH - Reproducibility of Results MH - Sensitivity and Specificity MH - *Surgery, Computer-Assisted/mt [Methods] MH - *Tomography, X-Ray Computed/mt [Methods] MH - Treatment Outcome AB - PURPOSE: To demonstrate the value of multidetector computed tomography (MDCT) and magnetic resonance imaging (MRI) in the preoperative assessment of orbital tumors, and to present, particularly, CT and MR image data fusion for surgical planning and performance in computer-assisted navigated surgery of orbital tumors. AB - MATERIALS AND METHODS: In this retrospective case series, 10 patients with orbital tumors and associated complaints underwent MDCT and MRI of the orbit. MDCT was performed at high resolution, with a bone window level setting in the axial plane. MRI was performed with an axial 3D T1-weighted (w) gradient-echo (GE) contrast-enhanced sequence, in addition to a standard MRI protocol. First, MDCT and MR images were used to diagnose tumorous lesions compared to histology as a standard of reference. Then, the image data sets from CT and 3D T1-w GE sequences were merged on a workstation to create CT-MR fusion images that were used for interventional planning and intraoperative image guidance. The intraoperative accuracy of the navigation unit was measured, defined as the deviation between the same landmark in the navigation image and the patient. Furthermore, the clinical preoperative status was compared to the patients' postoperative outcome. AB - RESULTS: Radiological and histological diagnosis, which revealed 7 benign and 3 malignant tumors, were concordant in 7 of 10 cases (70%). The CT-MR fusion images supported the surgeon in the preoperative planning and improved the surgical performance. The mean intraoperative accuracy of the navigation unit was 1.35mm. Postoperatively, orbital complaints showed complete regression in 6 cases, were ameliorated notably in 3 cases, and remained unchanged in 1 case. AB - CONCLUSION: CT and MRI are essential for the preoperative assessment of orbital tumors. CT-MR image data fusion is an accurate tool for planning the correct surgical procedure, and can improve surgical results in computer-assisted navigated surgery of orbital tumors. AB - Copyright (c) 2008 Elsevier Ireland Ltd. All rights reserved. ES - 1872-7727 IL - 0720-048X DI - S0720-048X(08)00632-3 DO - https://dx.doi.org/10.1016/j.ejrad.2008.11.003 PT - Clinical Trial PT - Journal Article ID - 19097718 [pubmed] ID - S0720-048X(08)00632-3 [pii] ID - 10.1016/j.ejrad.2008.11.003 [doi] PP - ppublish PH - 2008/10/27 [received] PH - 2008/11/02 [revised] PH - 2008/11/05 [accepted] LG - English EP - 20081220 DP - 2010 Feb DC - 20100217 EZ - 2008/12/23 09:00 DA - 2010/05/18 06:00 DT - 2008/12/23 09:00 YR - 2010 ED - 20100517 RD - 20100217 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19097718 <449. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19536599 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Stefanidis D AU - Wang F AU - Korndorffer JR Jr AU - Dunne JB AU - Scott DJ FA - Stefanidis, Dimitrios FA - Wang, Fikre FA - Korndorffer, James R Jr FA - Dunne, J Bruce FA - Scott, Daniel J IN - Stefanidis, Dimitrios. Division of Gastrointestinal and Minimally Invasive Surgery, Department of General Surgery, Carolinas Medical Center, Carolinas Simulation Center, Charlotte, NC 28203, USA. dimitrios.stefanidis@carolinas.org TI - Robotic assistance improves intracorporeal suturing performance and safety in the operating room while decreasing operator workload. SO - Surgical Endoscopy. 24(2):377-82, 2010 Feb AS - Surg Endosc. 24(2):377-82, 2010 Feb NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adult MH - Animals MH - Clinical Competence MH - Educational Measurement MH - Female MH - Fundoplication/ed [Education] MH - Fundoplication/is [Instrumentation] MH - *Fundoplication/mt [Methods] MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Prospective Studies MH - Robotics/ed [Education] MH - *Robotics MH - *Students, Medical/px [Psychology] MH - Suture Techniques/ed [Education] MH - *Suture Techniques/is [Instrumentation] MH - Swine MH - Video Games/sn [Statistics & Numerical Data] MH - Workload MH - Young Adult AB - BACKGROUND: Intracorporeal suturing is one of the most difficult laparoscopic tasks. The purpose of this study was to assess the impact of robotic assistance on novice suturing performance, safety, and workload in the operating room. AB - METHODS: Medical students (n = 34), without prior laparoscopic suturing experience, were enrolled in an Institutional Review Board-approved, randomized protocol. After viewing an instructional video, subjects were tested in intracorporeal suturing on two identical, live, porcine Nissen fundoplication models; they placed three gastro-gastric sutures using conventional laparoscopic instruments in one model and using robotic assistance (da Vinci) in the other, in random order. Each knot was objectively scored based on time, accuracy, and security. Injuries to surrounding structures were recorded. Workload was assessed using the validated National Aeronautics and Space Administration (NASA) task load index (TLX) questionnaire, which measures the subjects' self-reported performance, effort, frustration, and mental, physical, and temporal demands of the task. Analysis was by paired t-test; p < 0.05 was considered significant. AB - RESULTS: Compared with laparoscopy, robotic assistance enabled subjects to suture faster (595 +/- 22 s versus 459 +/- 137 s, respectively; p < 0.001), achieve higher overall scores (0 +/- 1 versus 95 +/- 128, respectively; p < 0.001), and commit fewer errors per knot (1.15 +/- 1.35 versus 0.05 +/- 0.26, respectively; p < 0.001). Subjects' overall score did not improve between the first and third attempt for laparoscopic suturing (0 +/- 0 versus 0 +/- 0; p = NS) but improved significantly for robotic suturing (49 +/- 100 versus 141 +/- 152; p < 0.001). Moreover, subjects indicated on the NASA-TLX scale that the task was more difficult to perform with laparoscopic instruments compared with robotic assistance (99 +/- 15 versus 57 +/- 23; p < 0.001). AB - CONCLUSIONS: Compared with standard laparoscopy, robotic assistance significantly improved intracorporeal suturing performance and safety of novices in the operating room while decreasing their workload. Moreover, the robot significantly shortened the learning curve of this difficult task. Further study is needed to assess the value of robotic assistance for experienced surgeons, and validated robotic training curricula need to be developed. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-009-0578-0 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 19536599 [pubmed] ID - 10.1007/s00464-009-0578-0 [doi] PP - ppublish PH - 2008/12/02 [received] PH - 2009/05/14 [accepted] PH - 2009/04/29 [revised] LG - English EP - 20090618 DP - 2010 Feb DC - 20100201 EZ - 2009/06/19 09:00 DA - 2010/04/23 06:00 DT - 2009/06/19 09:00 YR - 2010 ED - 20100422 RD - 20100201 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19536599 <450. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20073551 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Martinez CH AU - Chalasani V AU - Lim D AU - Nott L AU - Al-Bareeq RJ AU - Wignall GR AU - Stitt L AU - Pautler SE FA - Martinez, Carlos H FA - Chalasani, Venu FA - Lim, Darwin FA - Nott, Linda FA - Al-Bareeq, Reem J FA - Wignall, Geoffrey R FA - Stitt, Larry FA - Pautler, Stephen E IN - Martinez, Carlos H. Division of Urology, Department of Surgery, The University of Western Ontario, London, Ontario, Canada. TI - Effect of prostate gland size on the learning curve for robot-assisted laparoscopic radical prostatectomy: does size matter initially?. SO - Journal of Endourology. 24(2):261-6, 2010 Feb AS - J Endourol. 24(2):261-6, 2010 Feb NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Cohort Studies MH - Humans MH - *Laparoscopy MH - *Learning MH - Male MH - Middle Aged MH - Organ Size MH - Perioperative Care MH - Prostate/dg [Diagnostic Imaging] MH - *Prostate/pa [Pathology] MH - *Prostatectomy/ed [Education] MH - *Prostatectomy/mt [Methods] MH - Rectum/dg [Diagnostic Imaging] MH - *Robotics/ed [Education] MH - Time Factors MH - Ultrasonography AB - BACKGROUND AND PURPOSE: Widespread introduction of robot-assisted laparoscopic radical prostatectomy (RALRP) has led to multiple surgeons going through the learning curve (LC). One of the recommendations for surgeons on the LC for RALRP is to choose patients with smaller glands. We evaluated our LCs to determine whether prostate size influenced intraoperative outcomes and positive surgical margin rates. AB - PATIENTS AND METHODS: Data were obtained from a prospective database for the first 154 cases of RALRP performed by a single surgeon. Patients were divided into three groups based on prostate volume (PV): <40 cc (group 1), 40 to 60 cc (group 2), or >60 cc (group 3). PV was estimated by preoperative transrectal ultrasonography (TRUS) and correlated with pathologic weight (PW). Perioperative and immediate postoperative outcomes were evaluated. AB - RESULTS: A statistically significant difference in total operative times between the groups (206 minutes vs 201 minutes vs 233 minutes for groups 1, 2, and 3, respectively) was noted. With regard to individual intraoperative steps, the bladder neck reconstruction and anastomosis time was longer in group 3. No other statistically significant differences were noted. The Pearson correlation coefficient between PV estimation by TRUS and PW was r = 0.785, and an additional analysis based on PW supports the results of our study. AB - CONCLUSIONS: Prostate size influenced total operative times and the bladder neck reconstruction and anastomosis time. Our data support the use of preoperative TRUS to estimate PV and recommendations for surgeons starting on their LC to choose glands less than 60 cc. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2009.0325 PT - Clinical Trial PT - Journal Article ID - 20073551 [pubmed] ID - 10.1089/end.2009.0325 [doi] PP - ppublish LG - English DP - 2010 Feb DC - 20100210 EZ - 2010/01/16 06:00 DA - 2010/04/22 06:00 DT - 2010/01/16 06:00 YR - 2010 ED - 20100421 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20073551 <451. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20039827 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Boylu U AU - Oommen M AU - Raynor M AU - Lee BR AU - Thomas R FA - Boylu, Ugur FA - Oommen, Mathew FA - Raynor, Mathew FA - Lee, Benjamin R FA - Thomas, Raju IN - Boylu, Ugur. Department of Urology, Tulane University School of Medicine, New Orleans, Louisiana 70112, USA. ugur@ugurboylu.com TI - Robot-assisted laparoscopic radical prostatectomy in patients with previous abdominal surgery: a novel laparoscopic adhesiolysis technique. SO - Journal of Endourology. 24(2):229-32, 2010 Feb AS - J Endourol. 24(2):229-32, 2010 Feb NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - *Abdomen/su [Surgery] MH - Humans MH - Laparoscopes MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - *Prostatectomy/mt [Methods] MH - *Robotics/mt [Methods] MH - Surgical Instruments MH - Treatment Outcome AB - PURPOSE: We evaluated the feasibility and outcomes of performing a novel laparoscopic adhesiolysis technique before robot-assisted laparoscopic radical prostatectomy (RALRP) in patients with previous abdominal surgery. AB - PATIENTS AND METHODS: A total of 18 men with incision scars from previous abdominal surgeries underwent RALRP. A 12-mm trocar was placed at the lateral lower quadrant away from the incision site, and a teaching laparoscope was introduced into the peritoneal cavity. Meticulous adhesiolysis was performed through a single trocar to subsequently allow safe placement of additional robotic trocars. Age, type of previous surgery, total operative time, console time, anastomosis time, estimated blood loss, transfusion rate, complications, and conversion rate were recorded. AB - RESULTS: All patients had multiple abdominal surgeries. Mean operative time was 297 minutes, mean console time was 194 minutes, and mean estimated blood loss was 241 mL. No access-related complication and no conversion to open surgery occurred. AB - CONCLUSION: This novel laparoscopic technique of adhesiolysis with a teaching laparoscope through a single trocar facilitates safe placement of trocars and accomplishment of RALRP in patients with previous abdominal surgery. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2009.0237 PT - Clinical Trial PT - Journal Article ID - 20039827 [pubmed] ID - 10.1089/end.2009.0237 [doi] PP - ppublish LG - English DP - 2010 Feb DC - 20100210 EZ - 2009/12/31 06:00 DA - 2010/04/22 06:00 DT - 2009/12/31 06:00 YR - 2010 ED - 20100421 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20039827 <452. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 20039797 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Allaparthi S AU - Ramanathan R AU - Balaji KC FA - Allaparthi, Satya FA - Ramanathan, Rajan FA - Balaji, K C IN - Allaparthi, Satya. Division of Urology, Department of Surgery, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA. TI - Robotic partial cystectomy for bladder cancer: a single-institutional pilot study. SO - Journal of Endourology. 24(2):223-7, 2010 Feb AS - J Endourol. 24(2):223-7, 2010 Feb NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - *Cystectomy/mt [Methods] MH - Humans MH - Male MH - Middle Aged MH - Perioperative Care MH - Pilot Projects MH - *Robotics/mt [Methods] MH - *Urinary Bladder Neoplasms/su [Surgery] MH - Young Adult AB - OBJECTIVE: Open partial cystectomy has been used as a curative option for select group of patients with bladder cancer. In recent years, the da Vinci Surgical Robotic System is being increasingly used to perform complex urologic cancer surgeries. We report first on a consecutive cohort of patients undergoing robotic partial cystectomy (RPC) for bladder cancer. AB - METHODS: Three consecutive patients underwent RPC, two with diagnosis of papillary neoplasm of bladder and one with urachal adenocarcinoma at our institution from July 2008 to January 2009. Perioperative parameters were prospectively collected and analyzed after Institutional Review Board approval. AB - RESULTS: All three patients in the study were men with a median age of 50 years (range, 24-70 years). The RPC was completed transperitoneally in all three patients without the need for open conversion. The operative time, estimated blood loss, and time to hospital discharge for the three patients undergoing RPC were 185, 135, and 165 minutes; 25, 20, and 20 mL; and 5, 2, and 2 days, respectively. The percentage change in hematocrit after surgery was within 5% in all patients. There were no postoperative complications before discharge; however, one patient was readmitted and underwent small bowel resection secondary to bowel obstruction. Final pathology demonstrated high-grade carcinoma pT2bNxMx and pTaNxMx papillary urothelial carcinoma in two patients and invasive adenocarcinoma of the bladder pT3aNxMx in the remaining patient. The median follow-up was 6 months (range, 3-10 months). All three patients were alive with no signs of recurrent or metastatic disease on cystoscopic, cytological, or radiological follow-up. AB - CONCLUSIONS: RPC is technically feasible using the da Vinci Surgical Robotic System in select patients with bladder cancer without disease recurrence in the short term. A larger cohort with long-term follow-up is necessary to validate our results. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2009.0367 PT - Clinical Trial PT - Journal Article ID - 20039797 [pubmed] ID - 10.1089/end.2009.0367 [doi] PP - ppublish LG - English DP - 2010 Feb DC - 20100210 EZ - 2009/12/31 06:00 DA - 2010/04/22 06:00 DT - 2009/12/31 06:00 YR - 2010 ED - 20100421 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=20039797 <453. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19958156 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Haseebuddin M AU - Benway BM AU - Cabello JM AU - Bhayani SB FA - Haseebuddin, Mohammed FA - Benway, Brian M FA - Cabello, Jose M FA - Bhayani, Sam B IN - Haseebuddin, Mohammed. Division of Urologic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri 63110, USA. TI - Robot-assisted partial nephrectomy: evaluation of learning curve for an experienced renal surgeon. SO - Journal of Endourology. 24(1):57-61, 2010 Jan AS - J Endourol. 24(1):57-61, 2010 Jan NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - *Clinical Competence MH - Humans MH - *Kidney/su [Surgery] MH - Kidney Neoplasms/pa [Pathology] MH - Kidney Neoplasms/su [Surgery] MH - *Learning MH - Middle Aged MH - Nephrectomy/ae [Adverse Effects] MH - *Nephrectomy/ed [Education] MH - *Nephrectomy/mt [Methods] MH - *Physicians MH - Postoperative Complications/et [Etiology] MH - *Robotics MH - Time Factors MH - Treatment Outcome MH - Warm Ischemia AB - PURPOSE: The learning curve for robot-assisted partial nephrectomy (RAPN) has not been extensively studied. We therefore evaluated the learning curve of RAPN for a fellowship-trained laparoscopic surgeon with extensive prior experience with laparoscopic partial nephrectomy (LPN). We also examined the potential effect of tumor size on the learning curve. AB - PATIENTS AND METHODS: We prospectively evaluated 38 consecutive patients undergoing RAPN by a single surgeon (S.B.B.). Sixteen patients had tumors <2 cm, and 22 patients had tumors >2 cm. Warm ischemia times and overall operative times were recorded as indices of learning progression. AB - RESULTS: Average operative time for tumors <2 cm was 131.9 minutes (115.3-148.5 minutes) and for tumors >2 cm was 145.8 minutes (131.1-160.5 minutes). The difference between the operative times for tumors <2 and >2 cm was not statistically significant (p = 0.23). Average warm ischemia time for tumors <2 cm was 21 minutes (16.9-25.1 minutes) and for tumors >2 cm was 24.7 minutes (21.3-28.1 minutes). This difference was also not statistically significant (p = 0.20). Defined by the overall operative time, the learning curve for RAPN was 16 cases, and by ischemic time, the learning curve was 26 cases. Tumor size did not have an effect on the learning curve. AB - CONCLUSIONS: The learning curve for RAPN is short for surgeons already experienced with LPN. The learning curve for portions performed under warm ischemia is slightly longer, implying that the critical portions of the procedure require more experience to become facile. Tumor size does not appear to have a significant impact on the learning curve for surgeons experienced with LPN. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2008.0601 PT - Clinical Trial PT - Journal Article ID - 19958156 [pubmed] ID - 10.1089/end.2008.0601 [doi] PP - ppublish LG - English DP - 2010 Jan DC - 20100111 EZ - 2009/12/05 06:00 DA - 2010/03/11 06:00 DT - 2009/12/05 06:00 YR - 2010 ED - 20100310 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19958156 <454. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19455550 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hoekstra AV AU - Jairam-Thodla A AU - Rademaker A AU - Singh DK AU - Buttin BM AU - Lurain JR AU - Schink JC AU - Lowe MP FA - Hoekstra, Anna V FA - Jairam-Thodla, Arati FA - Rademaker, Alfred FA - Singh, Diljeet K FA - Buttin, Barbara M FA - Lurain, John R FA - Schink, Julian C FA - Lowe, M Patrick IN - Hoekstra, Anna V. Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, 250 East Superior Street, Chicago, IL 60611, USA. TI - The impact of robotics on practice management of endometrial cancer: transitioning from traditional surgery. SO - The International Journal Of Medical Robotics + Computer Assisted Surgery: MRCAS. 5(4):392-7, 2009 Dec AS - Int J Med Robot. 5(4):392-7, 2009 Dec NJ - The international journal of medical robotics + computer assisted surgery : MRCAS PI - Journal available in: Print PI - Citation processed from: Internet JC - 101250764 IO - Int J Med Robot SB - Index Medicus CP - England MH - Chicago/ep [Epidemiology] MH - *Endometrial Ablation Techniques/ut [Utilization] MH - *Endometrial Neoplasms/ep [Epidemiology] MH - *Endometrial Neoplasms/su [Surgery] MH - Female MH - Humans MH - Middle Aged MH - Outcome Assessment (Health Care) MH - *Practice Patterns, Physicians'/sn [Statistics & Numerical Data] MH - Prevalence MH - *Robotics/ut [Utilization] MH - *Surgery, Computer-Assisted/ut [Utilization] MH - Treatment Outcome MH - *Workload/sn [Statistics & Numerical Data] AB - BACKGROUND: Evaluation of the impact of a new robotic surgery programme on perioperative outcomes for endometrial cancer AB - METHODS: A prospective database of all patients undergoing staging for endometrial cancer during July 2007-July 2008 was collected and analysed. Demographic data and perioperative outcomes were compared between cases performed via laparotomy, laparoscopy and robotics. AB - RESULTS: Sixty-five patients underwent staging during the time of data collection (LAP-26, LSC-7, ROB-32). No difference in surgical volume in the year before vs. after robotics was identified. Median operative time for robotics and laparotomy was significantly less than for laparoscopy (p = 0.023). There was no significant difference in lymph node yields between the three groups (p = 0.92). Robotics was associated with significantly less blood loss (p < 0.0001). Complication rates were significantly lower in the robotic group compared to the laparotomy group (p = 0.05). Median hospital stay was 1 day for the minimally invasive groups. Total number of perioperative inpatient days decreased from 331 to 150 in one year. Practice management of endometrial cancer transitioned from a predominantly open approach (5.6% LSC) to robotics (11% LSC, 49% ROB) within 12 months. AB - CONCLUSIONS: Robotic surgery dramatically altered our management of endometrial cancer and was associated with a significant improvement in several perioperative outcomes when compared to laparotomy and laparoscopy. AB - Copyright (c) 2009 John Wiley & Sons, Ltd. ES - 1478-596X IL - 1478-5951 DO - https://dx.doi.org/10.1002/rcs.268 PT - Controlled Clinical Trial PT - Journal Article ID - 19455550 [pubmed] ID - 10.1002/rcs.268 [doi] PP - ppublish LG - English DP - 2009 Dec DC - 20091201 EZ - 2009/05/21 09:00 DA - 2010/02/23 06:00 DT - 2009/05/21 09:00 YR - 2009 ED - 20100222 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19455550 <455. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19916770 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - El Douaihy Y AU - Tan GY AU - Dorsey PJ AU - Jhaveri JK AU - Tewari AK FA - El Douaihy, Youssef FA - Tan, Gerald Y FA - Dorsey, Philip J FA - Jhaveri, Jay K FA - Tewari, Ashutosh K IN - El Douaihy, Youssef. LeFrak Institute of Robotic Surgery & Prostate Cancer Institute, James Buchanan Brady Foundation Department of Urology, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, New York 10065, USA. TI - Double-pigtail stenting of the ureters: technique for securing the ureteral orifices during robot-assisted radical prostatectomy for large median lobes. SO - Journal of Endourology. 23(12):1975-7, 2009 Dec AS - J Endourol. 23(12):1975-7, 2009 Dec NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Humans MH - Male MH - *Prostate/pa [Pathology] MH - *Prostate/su [Surgery] MH - *Prostatectomy/mt [Methods] MH - *Robotics MH - *Stents MH - *Ureter/su [Surgery] MH - Urinary Bladder/su [Surgery] AB - Patients with large median prostate lobes undergoing robot-assisted radical prostatectomy are at potential risk of ureteric orifice injury, during posterior bladder neck transection and vesicourethral anastomosis reconstruction. We describe our technique of in situ robot-assisted ureteral stenting with double-pigtail stents for accurate observation and preservation of the ureteral orifices. We have performed this maneuver in over 30 patients in our cohort of over 1500 patients undergoing robot-assisted radical prostatectomy to date--none of these patients developed urinary leak or bladder neck contracture, and had uneventful cystoscopic removal of stents at 6 weeks after surgery. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2009.0133 PT - Clinical Trial PT - Journal Article ID - 19916770 [pubmed] ID - 10.1089/end.2009.0133 [doi] PP - ppublish LG - English DP - 2009 Dec DC - 20091204 EZ - 2009/11/18 06:00 DA - 2010/02/04 06:00 DT - 2009/11/18 06:00 YR - 2009 ED - 20100203 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19916770 <456. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19891576 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Meeks JJ AU - Zhao LC AU - Greco KA AU - Wu SD AU - Nadler RB FA - Meeks, Joshua J FA - Zhao, Lee C FA - Greco, Kristin A FA - Wu, Simon D FA - Nadler, Robert B IN - Meeks, Joshua J. Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA. TI - Application of continuous tension to aid in performing the vesicourethral anastomosis for robot-assisted prostatectomy. SO - Journal of Endourology. 23(12):1941-4, 2009 Dec AS - J Endourol. 23(12):1941-4, 2009 Dec NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Anastomosis, Surgical/is [Instrumentation] MH - *Anastomosis, Surgical/mt [Methods] MH - Humans MH - Male MH - Middle Aged MH - Prostatectomy/is [Instrumentation] MH - *Prostatectomy/mt [Methods] MH - *Robotics MH - *Urethra/su [Surgery] MH - *Urinary Bladder/su [Surgery] AB - OBJECTIVES: Approximation of the bladder to urethra during robot-assisted laparoscopic prostatectomy (RALP) is a critical step toward achieving long-term continence. To determine the impact on surgical outcomes after RALP, we compare two techniques for constructing the vesicourethral anastomosis. AB - METHODS: One hundred fifty-four men underwent RALP by one surgeon between 2005 and 2007. The vesicourethral anastomosis was performed in a standard Van Velthoven fashion for the first 61 patients. The anastomosis in the remaining 93 patients was performed in a running fashion with the sutures under continuous tension applied by the surgical assistant and the third robotic arm. Operative times and surgical outcomes were recorded prospectively. AB - RESULTS: When comparing standard Van Velthoven to continuous tension anastomosis, we demonstrate equivalent oncologic outcomes, continence and time required for the anastomosis. Yet, the frequency of complications related to the anastomotic technique, such as urine leaks, bladder neck contractures and migrated hemo-lock clips, were significantly lower with the continuous tension technique compared to the standard Van Velthoven running anastomosis. AB - CONCLUSIONS: Performing the vesicourethral anastomosis under continuous tension demonstrated improved outcomes compared to the Van Velthoven anastomosis by allowing persistent close apposition of the bladder to urethra. Additionally, the learning curve associated with implementation of a new anastomotic technique was negligible. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2009.0360 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 19891576 [pubmed] ID - 10.1089/end.2009.0360 [doi] PP - ppublish LG - English DP - 2009 Dec DC - 20091204 EZ - 2009/11/07 06:00 DA - 2010/02/04 06:00 DT - 2009/11/07 06:00 YR - 2009 ED - 20100203 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19891576 <457. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19630506 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hong JY AU - Lee SJ AU - Rha KH AU - Roh GU AU - Kwon SY AU - Kil HK FA - Hong, Jeong-Yeon FA - Lee, Sung Jin FA - Rha, Koon Ho FA - Roh, Go Un FA - Kwon, So Young FA - Kil, Hae Keum IN - Hong, Jeong-Yeon. Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea. jenyhongg@yuhs.ac TI - Effects of thoracic epidural analgesia combined with general anesthesia on intraoperative ventilation/oxygenation and postoperative pulmonary complications in robot-assisted laparoscopic radical prostatectomy. SO - Journal of Endourology. 23(11):1843-9, 2009 Nov AS - J Endourol. 23(11):1843-9, 2009 Nov NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Aged MH - *Analgesia, Epidural/ae [Adverse Effects] MH - *Anesthesia, General/ae [Adverse Effects] MH - Blood Gas Analysis MH - Demography MH - Humans MH - *Intraoperative Care/ae [Adverse Effects] MH - Laparoscopy MH - Male MH - Middle Aged MH - Postoperative Complications/et [Etiology] MH - *Postoperative Complications/pp [Physiopathology] MH - *Prostatectomy MH - *Pulmonary Ventilation/ph [Physiology] MH - *Robotics MH - Thoracic Surgery AB - PURPOSE: The purpose of this study was to evaluate the effects of thoracic epidural analgesia (TEA) on intraoperative ventilation/oxygenation and postoperative pulmonary complications in robot-assisted laparoscopic radical prostatectomy requiring high-pressure pneumoperitoneum and the extreme head-down position. AB - METHODS: Seventy-two patients (age range, 58-76 years) scheduled for elective robot-assisted laparoscopic radical prostatectomy were randomly assigned to receive either TEA combined with general anesthesia (TEA group, n = 36) or general anesthesia (GA group, n = 36). T4-sensory block using 1% lidocaine was continuously provided during surgery in the TEA group but not in the GA group. The mode of ventilation was volume controlled with a linear ramp in the pressure wave. Maximum peak inspiratory pressure was preset at 35 mm Hg, and no positive end-expiratory pressure was administered to the patients. Minute ventilation was adjusted to maintain end-tidal CO(2) between 30 and 35 mm Hg by changing respiratory rate during surgery. Intraoperative ventilatory parameters and blood gas analyses were checked. Clinical and radiological pulmonary complications were observed for 3 days postoperatively. AB - RESULTS: Patients in the TEA group showed significantly lower peak inspiratory pressure and higher dynamic compliance with larger expiratory tidal volume during surgery than those in the GA group. They had significantly better oxygenation and lower concentrations of lactate on arterial blood gas analysis than the GA group. Postoperative clinical and radiological complication rates were not significantly different. AB - CONCLUSIONS: TEA combined with general anesthesia improved intraoperative ventilation/oxygenation. Although clinical and radiologic pulmonary complications were not significantly influenced, TEA can be considered an option for patients with limited reserve capacity or preexisting impairments of visceral blood flow. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2009.0059 PT - Journal Article PT - Randomized Controlled Trial ID - 19630506 [pubmed] ID - 10.1089/end.2009.0059 [doi] PP - ppublish LG - English DP - 2009 Nov DC - 20091106 EZ - 2009/07/28 09:00 DA - 2010/01/27 06:00 DT - 2009/07/28 09:00 YR - 2009 ED - 20100126 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19630506 <458. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18802897 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Draaisma WA AU - Gooszen HG AU - Consten EC AU - Broeders IA FA - Draaisma, Werner A FA - Gooszen, Hein G FA - Consten, Esther C J FA - Broeders, Ivo A M J IN - Draaisma, Werner A. Department of Surgery, Meander Medical Center, Amersfoort, The Netherlands. TI - Mid-term results of robot-assisted laparoscopic repair of large hiatal hernia: a symptomatic and radiological prospective cohort study. SO - Surgical Technology International. 17:165-70, 2008 AS - Surg Technol Int. 17:165-70, 2008 NJ - Surgical technology international PI - Journal available in: Print PI - Citation processed from: Print JC - 9604509 IO - Surg Technol Int SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - Female MH - *Hernia, Hiatal/di [Diagnosis] MH - *Hernia, Hiatal/su [Surgery] MH - Humans MH - *Laparoscopy/mt [Methods] MH - Longitudinal Studies MH - Male MH - Middle Aged MH - Prospective Studies MH - *Robotics/mt [Methods] MH - *Surgery, Computer-Assisted/mt [Methods] MH - Treatment Outcome AB - Studies reporting on the recurrence rate after laparoscopic repair of large hiatal hernias (HH), including anatomical asymptomatic recurrence, are scarce. This prospective cohort study evaluated the symptomatic and objective outcome of robot-assisted laparoscopic HH repair up to more than 1 year after surgery. A prospective cohort study was performed on 40 consecutive patients with emphasis on operating times, blood loss, intra- and postoperative complications, symptomatic outcome, and anatomical recurrence rate at a minimum of 1 year after surgery. Robot-assisted laparoscopic HH repair proved to be an effective technique with a relatively low mid-term recurrence rate in this prospective series. The operating team experienced the support of the robotic system as beneficial, especially in the dissection of the hernia sac and extensive crural repair. IS - 1090-3941 IL - 1090-3941 PT - Clinical Trial PT - Journal Article ID - 18802897 [pubmed] PP - ppublish LG - English DP - 2008 DC - 20080919 EZ - 2008/09/20 09:00 DA - 2010/01/06 06:00 DT - 2008/09/20 09:00 YR - 2008 ED - 20100105 RD - 20080919 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18802897 <459. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19901144 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tait AR AU - Voepel-Lewis T AU - Moscucci M AU - Brennan-Martinez CM AU - Levine R FA - Tait, Alan R FA - Voepel-Lewis, Terri FA - Moscucci, Mauro FA - Brennan-Martinez, Colleen M FA - Levine, Robert IN - Tait, Alan R. Department of Anesthesiology, University of Michigan Health System, 1500 E Medical Center Dr, Ann Arbor, MI 48109, USA. atait@umich.edu TI - Patient comprehension of an interactive, computer-based information program for cardiac catheterization: a comparison with standard information. SO - Archives of Internal Medicine. 169(20):1907-14, 2009 Nov 09 AS - Arch Intern Med. 169(20):1907-14, 2009 Nov 09 NJ - Archives of internal medicine PI - Journal available in: Print PI - Citation processed from: Internet JC - 0372440, 7fs IO - Arch. Intern. Med. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776761 OI - Source: NLM. NIHMS156453 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Aged, 80 and over MH - *Cardiac Catheterization/mt [Methods] MH - Communication MH - *Comprehension MH - *Computer-Assisted Instruction/mt [Methods] MH - Confidence Intervals MH - Disclosure MH - Female MH - Health Knowledge, Attitudes, Practice MH - Humans MH - *Informed Consent MH - Male MH - Middle Aged MH - *Patient Education as Topic/og [Organization & Administration] MH - Probability MH - Program Evaluation MH - Reference Values MH - Risk Assessment MH - Writing/st [Standards] AB - BACKGROUND: Several studies suggest that standard verbal and written consent information for treatment is often poorly understood by patients and their families. The present study examines the effect of an interactive computer-based information program on patients' understanding of cardiac catheterization. AB - METHODS: Adult patients scheduled to undergo diagnostic cardiac catheterization (n = 135) were randomized to receive details about the procedure using either standard institutional verbal and written information (SI) or interactive computerized information (ICI) preloaded on a laptop computer. Understanding was measured using semistructured interviews at baseline (ie, before information was given), immediately following cardiac catheterization (early understanding), and 2 weeks after the procedure (late understanding). The primary study outcome was the change from baseline to early understanding between groups. AB - RESULTS: Subjects randomized to the ICI intervention had significantly greater improvement in understanding compared with those who received the SI (net change, 0.81; 95% confidence interval, 0.01-1.6). Significantly more subjects in the ICI group had complete understanding of the risks of cardiac catheterization (53.6% vs 23.1%) (P = .001) and options for treatment (63.2% vs 46.2%) (P = .048) compared with the SI group. Several predictors of improved understanding were identified, including baseline knowledge (P < .001), younger age (P = .002), and use of the ICI (P = .003). AB - CONCLUSIONS: Results suggest that an interactive computer-based information program for cardiac catheterization may be more effective in improving patient understanding than conventional written consent information. This technology, therefore, holds promise as a means of presenting understandable detailed information regarding a variety of medical treatments and procedures. ES - 1538-3679 IL - 0003-9926 DI - 169/20/1907 DO - https://dx.doi.org/10.1001/archinternmed.2009.390 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, N.I.H., Extramural ID - 19901144 [pubmed] ID - 169/20/1907 [pii] ID - 10.1001/archinternmed.2009.390 [doi] ID - PMC2776761 [pmc] ID - NIHMS156453 [mid] PP - ppublish GI - No: R01 HD053594 Organization: (HD) *NICHD NIH HHS* Country: United States No: R01 HD053594-01A1 Organization: (HD) *NICHD NIH HHS* Country: United States No: R41 HL087488 Organization: (HL) *NHLBI NIH HHS* Country: United States No: R41 HL087488-01A1 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English DP - 2009 Nov 09 DC - 20091110 EZ - 2009/11/11 06:00 DA - 2009/12/16 06:00 DT - 2009/11/11 06:00 YR - 2009 ED - 20091209 RD - 20161122 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19901144 <460. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19556040 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Eggers G AU - Muhling J AU - Hofele C FA - Eggers, Georg FA - Muhling, Joachim FA - Hofele, Christof IN - Eggers, Georg. Department of Oral and Cranio-Maxillofacial Surgery, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany. georg.eggers@med.uni-heidelberg.de TI - Clinical use of navigation based on cone-beam computer tomography in maxillofacial surgery. SO - British Journal of Oral & Maxillofacial Surgery. 47(6):450-4, 2009 Sep AS - Br J Oral Maxillofac Surg. 47(6):450-4, 2009 Sep NJ - The British journal of oral & maxillofacial surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - azr, 8405235 IO - Br J Oral Maxillofac Surg SB - Dental Journals SB - Index Medicus CP - Scotland MH - Adolescent MH - Adult MH - *Cone-Beam Computed Tomography MH - Eyelids/dg [Diagnostic Imaging] MH - Eyelids/su [Surgery] MH - Facial Bones/dg [Diagnostic Imaging] MH - *Facial Bones/su [Surgery] MH - Female MH - Foreign Bodies/dg [Diagnostic Imaging] MH - *Foreign Bodies/su [Surgery] MH - Humans MH - Male MH - Middle Aged MH - *Surgery, Computer-Assisted/mt [Methods] MH - Young Adult AB - Image-guidance in maxillofacial surgery is based predominantly on computed tomographic (CT) images. Its main disadvantage is the considerable amount of radiation to which the patient is exposed, and dental metal artefacts. Recently, a new class of devices based on the concept of cone-beam computed tomography (CBCT) has been introduced for maxillofacial imaging, which we have investigated. In a clinical study, the first seven patients to be operated using a navigation system based on CBCT images, were evaluated. In all cases patient to image recording was uneventful and the surgical objective was reached. The guidance given by the navigation system was helpful. CBCT is an alternative to conventional CT, gives a lower dose of radiation, and costs less. Limitations in the quality of the images and the size of the field of view may restrict its use. It is suitable for image-guided surgery using a navigation system as long as the images show enough of the relevant anatomy and pathology. ES - 1532-1940 IL - 0266-4356 DI - S0266-4356(09)00176-4 DO - https://dx.doi.org/10.1016/j.bjoms.2009.04.034 PT - Clinical Trial PT - Journal Article ID - 19556040 [pubmed] ID - S0266-4356(09)00176-4 [pii] ID - 10.1016/j.bjoms.2009.04.034 [doi] PP - ppublish PH - 2009/04/30 [accepted] LG - English EP - 20090624 DP - 2009 Sep DC - 20090817 EZ - 2009/06/27 09:00 DA - 2009/11/17 06:00 DT - 2009/06/27 09:00 YR - 2009 ED - 20091116 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19556040 <461. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19698020 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Finley DS AU - Osann K AU - Chang A AU - Santos R AU - Skarecky D AU - Ahlering TE FA - Finley, David S FA - Osann, Kathryn FA - Chang, Alexandra FA - Santos, Rosanne FA - Skarecky, Douglas FA - Ahlering, Thomas E IN - Finley, David S. Institute of Urologic Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA. dfinley@mednet.ucla.edu TI - Hypothermic robotic radical prostatectomy: impact on continence. SO - Journal of Endourology. 23(9):1443-50, 2009 Sep AS - J Endourol. 23(9):1443-50, 2009 Sep NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Aged MH - Case-Control Studies MH - Humans MH - *Hypothermia, Induced/ae [Adverse Effects] MH - Incontinence Pads MH - Kaplan-Meier Estimate MH - Learning MH - Male MH - Multivariate Analysis MH - Prostate/ir [Innervation] MH - Prostate/pa [Pathology] MH - Prostate/su [Surgery] MH - *Prostatectomy/ae [Adverse Effects] MH - *Robotics MH - Temperature MH - Time Factors MH - *Urinary Incontinence/et [Etiology] AB - INTRODUCTION: Radical prostatectomy undoubtedly causes inflammatory damage to surrounding neuromuscular tissues (i.e., bladder, urethra, and nerves) that may contribute to urinary incontinence. We report the use of local hypothermia during robot-assisted laparoscopic prostatectomy to attenuate this injury. AB - METHODS: Regional pelvic cooling was achieved using cold intracorporeal irrigation and an endorectal cooling balloon (ECB). In all, 115 men undergoing hypothermic robot-assisted laparoscopic radical prostatectomy (hRLP) (case #667-782) were prospectively compared with a historical cohort (case #1-666). Intracorporeal rectal and neurovascular bundle temperatures (T) and intrarectal temperatures were measured. Continence was defined as zero urinary pads. Kaplan-Meier analysis of time to zero pads and multivariate Cox proportional hazards regression was used. AB - RESULTS: Hypothermia was achieved in 112/115 patients; 6 were excluded (3 ECB malfunction, 2 prior radiation, and 1 completion prostatectomy). Median endorectal T = 18.7 degrees C (range 9.1-29.5 degrees C). Mean intracorporeal T = 25.58 degrees C (ECB + irrigation, range 19.4-34.0 degrees C). Three and 12-month hRLP zero pad rates were 81% to 89% and 100% for initial and extended cooling groups versus 65% and 89% for controls. Return to continence was significantly faster for hRLP versus controls: median time to zero pad use was 39 days for hRLP versus 62 days for controls. Multivariate analysis adjusting for American Urological Association (AUA) symptom score, nerve-sparing surgery, learning curve, international index of erectile function-5, age, and prostate weight demonstrated a significantly faster return to continence (hazard ratio = 1.526; 95% CI 1.11, 2.09). Trends toward improved continence were observed with colder temperatures and older patients. AB - CONCLUSIONS: Local hypothermia during prostatectomy resulted in a significant improvement in early postoperative zero pad continence rates. Longer and deeper cooling appears to be associated with improved continence, particularly among older patients. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2009.0411 PT - Clinical Trial PT - Journal Article ID - 19698020 [pubmed] ID - 10.1089/end.2009.0411 [doi] PP - ppublish LG - English DP - 2009 Sep DC - 20090909 EZ - 2009/08/25 09:00 DA - 2009/11/13 06:00 DT - 2009/08/25 09:00 YR - 2009 ED - 20091112 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19698020 <462. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19694528 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Casey JT AU - Meeks JJ AU - Greco KA AU - Wu SD AU - Nadler RB FA - Casey, Jessica T FA - Meeks, Joshua J FA - Greco, Kristin A FA - Wu, Simon D FA - Nadler, Robert B IN - Casey, Jessica T. Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA. TI - Outcomes of locally advanced (T3 or greater) prostate cancer in men undergoing robot-assisted laparoscopic prostatectomy. SO - Journal of Endourology. 23(9):1519-22, 2009 Sep AS - J Endourol. 23(9):1519-22, 2009 Sep NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Aged MH - Demography MH - Humans MH - *Laparoscopy MH - Male MH - Middle Aged MH - Neoplasm Staging MH - Postoperative Care MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Robotics MH - Treatment Outcome AB - OBJECTIVES: Despite nearly equivalent outcomes between open and robot-assisted laparoscopic prostatectomy (RALP) for organ-confined prostate cancer (PCa), the role of primary treatment with RALP in men with locally advanced (T3 or greater) PCa has not been described in detail. We report our experience with RALP for pathologically advanced disease. AB - PATIENTS AND METHODS: From October 2005 to November 2008, 220 RALPs were performed by a single surgeon (R.B.N.). Outcomes were assessed prospectively in an institutional review board-approved database. AB - RESULTS: Of 220 RALPs, 35 (15.9%) were performed for pT3 PCa; none of them were identified preoperatively. There was no difference in operative time compared with patients with pT2 disease (271 vs. 295 minutes, p = 0.09). The positive surgical margin (PSM) rate was 20% compared with 4.9% for pT2 (p = 0.004). Sural nerve grafts were performed in 20%, and 57% had bilateral nerve sparing. The use of bilateral or unilateral nerve sparing was not associated with increased PSM (p = 0.85). Biochemical recurrence occurred in 28.6% of men with pT3 disease over an average of 13 months of follow-up time, 30% of which occurred in men with a PSM. At 6 months, an 85% continence rate was achieved, and at 1 year continence was 100% for pT3. Compared with pT2, men with advanced disease had similar recovery after RALP based on postsurgery questionnaires. AB - CONCLUSIONS: RALP is a feasible approach to patients with pathologically advanced PCa as 71% were without evidence of disease at 13 months postoperatively. PSM rate (20%) is comparable to previously reported open PSM rates (24-66%). ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2009.0388 PT - Clinical Trial PT - Journal Article ID - 19694528 [pubmed] ID - 10.1089/end.2009.0388 [doi] PP - ppublish LG - English DP - 2009 Sep DC - 20090909 EZ - 2009/08/22 09:00 DA - 2009/11/13 06:00 DT - 2009/08/22 09:00 YR - 2009 ED - 20091112 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19694528 <463. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19619065 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Yee DS AU - Narula N AU - Amin MB AU - Skarecky DW AU - Ahlering TE FA - Yee, David S FA - Narula, Navneet FA - Amin, Mahul B FA - Skarecky, Douglas W FA - Ahlering, Thomas E IN - Yee, David S. Department of Urology, University of California, Irvine Medical Center, Orange, California, USA. davidyee74@msn.com TI - Robot-assisted radical prostatectomy: current evaluation of surgical margins in clinically low-, intermediate-, and high-risk prostate cancer. SO - Journal of Endourology. 23(9):1461-5, 2009 Sep AS - J Endourol. 23(9):1461-5, 2009 Sep NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - Humans MH - Laparoscopy MH - Male MH - Middle Aged MH - Preoperative Care MH - Prostate/pa [Pathology] MH - Prostate/su [Surgery] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Risk Factors MH - *Robotics/mt [Methods] AB - PURPOSE: Concern exists over a lack of tactile sensation and positive surgical margins (PSMs) in patients undergoing robot-assisted radical prostatectomy. We report our PSM rates in our most current 500 cases and particularly in clinically high-risk disease. AB - MATERIALS AND METHODS: After implementation of our present technique at case #251, we report PSM rates according to pathologic stage and D'Amico's risk stratification: low risk (prostate-specific antigen [PSA] <10, Gleason score [GS] 5-6, cT1-T2A), intermediate risk (PSA 10-20, GS 7, cT2B), and high risk (PSA >20, GS 8-10, cT3). Patients with cT2b/T3 disease or GS 8 to 10 and multiple cores with >30% involvement underwent wide excision of the neurovascular bundle. PSM was defined as ink on tumor. AB - RESULTS: The overall PSM rate was 7.4%: pT2 = 3.1%, pT3 = 15.9%, and pT4 = 55.6%. PSMs occurred in 13 (4.9%) low, 10 (5.8%) intermediate, and 14 (22.6%) high D'Amico risk patients. Of the 62 high-risk patients, the median PSA was 6.9 (range 2.2-97.9); biopsy GS was 6 to 7 (26%) and 8 to 10 (74%). For preoperatively palpable disease, the PSM rate was 9.9%: cT1 = 6.0%, cT2 = 7.7%, and cT3 = 26.3%. No PSMs occurred along the neurovascular bundle. AB - CONCLUSION: Since 2005, 500 men with clinically low-, intermediate-, and high-risk prostate cancer have undergone robot-assisted radical prostatectomy with acceptable surgical margin rates. In patients with high-risk and usually palpable disease, PSM rates were also acceptable despite the lack of tactile sensation with the robot. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2009.0144 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 19619065 [pubmed] ID - 10.1089/end.2009.0144 [doi] PP - ppublish LG - English DP - 2009 Sep DC - 20090909 EZ - 2009/07/22 09:00 DA - 2009/11/13 06:00 DT - 2009/07/22 09:00 YR - 2009 ED - 20091112 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19619065 <464. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19781415 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Mahabadi AA AU - Bamberg F AU - Toepker M AU - Schlett CL AU - Rogers IS AU - Nagurney JT AU - Brady TJ AU - Hoffmann U AU - Truong QA FA - Mahabadi, Amir A FA - Bamberg, Fabian FA - Toepker, Michael FA - Schlett, Christopher L FA - Rogers, Ian S FA - Nagurney, John T FA - Brady, Thomas J FA - Hoffmann, Udo FA - Truong, Quynh A IN - Mahabadi, Amir A. Cardiac MR PET CT Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. TI - Association of aortic valve calcification to the presence, extent, and composition of coronary artery plaque burden: from the Rule Out Myocardial Infarction using Computer Assisted Tomography (ROMICAT) trial. SO - American Heart Journal. 158(4):562-8, 2009 Oct AS - Am Heart J. 158(4):562-8, 2009 Oct NJ - American heart journal PI - Journal available in: Print PI - Citation processed from: Internet JC - 0370465 IO - Am. Heart J. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764241 OI - Source: NLM. NIHMS136584 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - *Aortic Valve MH - Calcinosis/co [Complications] MH - *Calcinosis/dg [Diagnostic Imaging] MH - *Coronary Angiography/mt [Methods] MH - Coronary Artery Disease/co [Complications] MH - *Coronary Artery Disease/dg [Diagnostic Imaging] MH - Female MH - Follow-Up Studies MH - Heart Valve Diseases/co [Complications] MH - *Heart Valve Diseases/dg [Diagnostic Imaging] MH - Humans MH - Male MH - Middle Aged MH - *Myocardial Infarction/dg [Diagnostic Imaging] MH - Myocardial Infarction/et [Etiology] MH - Prospective Studies MH - Reproducibility of Results MH - Risk Factors MH - *Tomography, X-Ray Computed/mt [Methods] AB - BACKGROUND: Aortic valve calcification (AVC) is associated with cardiovascular risk factors and coronary artery calcification. We sought to determine whether AVC is associated with the presence and extent of overall plaque burden, as well as to plaque composition (calcified, mixed, and noncalcified). AB - METHODS: We examined 357 subjects (mean age 53 +/- 12 years, 61% male) who underwent contrast-enhanced electrocardiogram-gated 64-slice multidetector computed tomography from the ROMICAT trial for the assessment of presence and extent of coronary plaque burden according to the 17-coronary segment model and presence of AVC. AB - RESULTS: Patients with AVC (n = 37, 10%) were more likely than those without AVC (n = 320, 90%) to have coexisting presence of any coronary plaque (89% vs 46%, P < .001) and had a greater extent of coronary plaque burden (6.4 vs 1.8 segments, P < .001). Those with AVC had >3-fold increase odds of having any plaque (adjusted odds ratio [OR] 3.6, P = .047) and an increase of 2.5 segments of plaque (P < .001) as compared to those without AVC. When stratified by plaque composition, AVC was associated most with calcified plaque (OR 5.2, P = .004), then mixed plaque (OR 3.2, P = .02), but not with noncalcified plaque (P = .96). AB - CONCLUSION: Aortic valve calcification is associated with the presence and greater extent of coronary artery plaque burden and may be part of the later stages of the atherosclerosis process, as its relation is strongest with calcified plaque, less with mixed plaque, and nonsignificant with noncalcified plaque. If AVC is present, consideration for aggressive medical therapy may be warranted. ES - 1097-6744 IL - 0002-8703 DI - S0002-8703(09)00565-1 DO - https://dx.doi.org/10.1016/j.ahj.2009.07.027 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 19781415 [pubmed] ID - S0002-8703(09)00565-1 [pii] ID - 10.1016/j.ahj.2009.07.027 [doi] ID - PMC2764241 [pmc] ID - NIHMS136584 [mid] PP - ppublish PH - 2009/05/02 [received] PH - 2009/07/24 [accepted] GI - No: T32 HL076136-05 Organization: (HL) *NHLBI NIH HHS* Country: United States No: T32 HL076136 Organization: (HL) *NHLBI NIH HHS* Country: United States No: R01 HL080053 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30 HL093806-01 Organization: (HL) *NHLBI NIH HHS* Country: United States No: R01 HL080053-03 Organization: (HL) *NHLBI NIH HHS* Country: United States No: L30 HL093806 Organization: (HL) *NHLBI NIH HHS* Country: United States No: K23 HL098370 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English DP - 2009 Oct DC - 20090928 EZ - 2009/09/29 06:00 DA - 2009/10/21 06:00 DT - 2009/09/29 06:00 YR - 2009 ED - 20091020 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19781415 <465. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18704439 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hemal AK AU - Kumar A FA - Hemal, Ashok K FA - Kumar, Anup IN - Hemal, Ashok K. Department of Urology, All India Institute of Medical Sciences, New Delhi, India. ahemal@wfubmc.edu TI - A prospective comparison of laparoscopic and robotic radical nephrectomy for T1-2N0M0 renal cell carcinoma. SO - World Journal of Urology. 27(1):89-94, 2009 Feb AS - World J Urol. 27(1):89-94, 2009 Feb NJ - World journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - bry, 8307716 IO - World J Urol SB - Index Medicus CP - Germany MH - *Carcinoma, Renal Cell/pa [Pathology] MH - *Carcinoma, Renal Cell/su [Surgery] MH - Feasibility Studies MH - Female MH - Humans MH - *Kidney Neoplasms/pa [Pathology] MH - *Kidney Neoplasms/su [Surgery] MH - *Laparoscopy MH - Male MH - Middle Aged MH - Neoplasm Staging MH - *Nephrectomy/mt [Methods] MH - Prospective Studies MH - *Robotics AB - OBJECTIVES: We prospectively evaluated the safety, feasibility, and efficiency of robotic radical nephrectomy (RRN) for localized renal tumors (T1-2N0M0) and compared this with laparoscopic radical nephrectomy (LRN). AB - MATERIALS AND METHODS: Between October 2006 to August 2007, a prospective data analysis of 15 cases of renal cell carcinoma (RCC) stage T1-2N0M0, undergoing RRN was done. These patients were compared with a contemporary cohort of 15 patients of RCC with clinical stage T1-2N0M0, undergoing LRN. To keep comparison robust, all cases were performed by a single surgeon. Demographic, intra-operative, post-operative outcomes, pathological characteristics and follow-up data of the two groups were recorded and analyzed statistically. AB - RESULTS: Patients in group A (RRN) experienced significantly (P = 0.001) long operating time than group B (LRN). However, mean estimated blood loss, intra-operative and post-operative complications, blood transfusion rate, analgesic requirement, hospital stay and convalescence were comparable in two groups (P < 0.05). There was one conversion to open surgery in group A, and none in group B. The mean follow-up was comparable in two groups (8.3 and 9.1 months, respectively, in group A and B, P = 0.09). There were no local, port-site or distal recurrences in either group. AB - CONCLUSIONS: Robotic radical nephrectomy is a safe, feasible and effective for performing radical nephrectomy for localized RCC. Both groups (RRN and LRN) had comparable intra-operative, peri-operative, post-operative and oncological outcomes except for longer operating time with increased cost for RRN. In this comparative study, there were no outstanding benefits of RRN observed over LRN for localized RCC. ES - 1433-8726 IL - 0724-4983 DO - https://dx.doi.org/10.1007/s00345-008-0321-9 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 18704439 [pubmed] ID - 10.1007/s00345-008-0321-9 [doi] PP - ppublish PH - 2007/12/04 [received] PH - 2008/07/28 [accepted] LG - English EP - 20080813 DP - 2009 Feb DC - 20090123 EZ - 2008/08/16 09:00 DA - 2009/09/30 06:00 DT - 2008/08/16 09:00 YR - 2009 ED - 20090929 RD - 20090123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18704439 <466. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19622983 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lowe MP AU - Johnson PR AU - Kamelle SA AU - Kumar S AU - Chamberlain DH AU - Tillmanns TD FA - Lowe, M Patrick FA - Johnson, Peter R FA - Kamelle, Scott A FA - Kumar, Saurabh FA - Chamberlain, Donald H FA - Tillmanns, Todd D IN - Lowe, M Patrick. Department of Obstetrics and Gynecology, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL 60611, USA. mpatricklowe@mac.com TI - A multiinstitutional experience with robotic-assisted hysterectomy with staging for endometrial cancer. SO - Obstetrics & Gynecology. 114(2 Pt 1):236-43, 2009 Aug AS - Obstet Gynecol. 114(2 Pt 1):236-43, 2009 Aug NJ - Obstetrics and gynecology PI - Journal available in: Print PI - Citation processed from: Print JC - oc2, 0401101 IO - Obstet Gynecol SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Blood Loss, Surgical MH - Carcinoma/pa [Pathology] MH - *Carcinoma/su [Surgery] MH - Endometrial Neoplasms/pa [Pathology] MH - *Endometrial Neoplasms/su [Surgery] MH - Female MH - Humans MH - *Hysterectomy/mt [Methods] MH - Intraoperative Complications MH - Length of Stay MH - Middle Aged MH - *Neoplasm Staging/mt [Methods] MH - Postoperative Complications MH - *Robotics AB - OBJECTIVE: To report perioperative outcomes and learning curve characteristics from a multiinstitutional experience with robotic-assisted surgical staging for endometrial cancer. AB - METHODS: A multiinstitutional robotic surgical consortium was created to evaluate the usefulness of robotics for gynecologic oncology surgery. An analysis of a multiinstitutional database of all patients who underwent robotic surgery for endometrial carcinoma between April 2003 and January 2009 was performed. Records were reviewed for demographic data and perioperative outcomes. Individual surgeon outcomes were analyzed as well in an attempt to evaluate characteristics of learning with incorporation of robotic technology. AB - RESULTS: Four hundred five patients were identified who underwent robotic surgery for endometrial cancer. Mean age was 62.2 years and mean body mass index was 32.4. Fifty-five percent of patients reported a prior abdominal surgery. Final pathologic analysis demonstrated that 89.6% of all patients had stage I and II disease. Mean operative time was 170.5 minutes. Mean estimated blood loss was 87.5 mL. Mean lymph node count was 15.5. Mean hospital stay was 1.8 days. Intraoperative complications occurred in 3.5% of the patients and conversion to laparotomy occurred in 6.7%. Postoperative complications were reported in 14.6% of the patients. For the group, fewer than 10 cases were required to achieve proficiency with the procedure. AB - CONCLUSION: Robotic technology may level the playing field between the novice and expert laparoscopist for endometrial cancer staging. Prospective trials should be undertaken to compare robotic and laparoscopic approaches to treat endometrial cancer. AB - LEVEL OF EVIDENCE: III. IS - 0029-7844 IL - 0029-7844 DI - 00006250-200908000-00008 DO - https://dx.doi.org/10.1097/AOG.0b013e3181af2a74 PT - Clinical Trial PT - Journal Article PT - Multicenter Study ID - 19622983 [pubmed] ID - 10.1097/AOG.0b013e3181af2a74 [doi] ID - 00006250-200908000-00008 [pii] PP - ppublish LG - English DP - 2009 Aug DC - 20090722 EZ - 2009/07/23 09:00 DA - 2009/09/26 06:00 DT - 2009/07/23 09:00 YR - 2009 ED - 20090925 RD - 20091026 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19622983 <467. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19281468 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ficarra V AU - Novara G AU - Fracalanza S AU - D'Elia C AU - Secco S AU - Iafrate M AU - Cavalleri S AU - Artibani W FA - Ficarra, Vincenzo FA - Novara, Giacomo FA - Fracalanza, Simonetta FA - D'Elia, Carolina FA - Secco, Silvia FA - Iafrate, Massimo FA - Cavalleri, Stefano FA - Artibani, Walter IN - Ficarra, Vincenzo. Department of Oncological and Surgical Sciences, Urology Clinic, University of Padua, Padua, Italy. vincenzo.ficarra@unipd.it TI - A prospective, non-randomized trial comparing robot-assisted laparoscopic and retropubic radical prostatectomy in one European institution. CM - Comment in: Eur Urol. 2011 Sep;60(3):599-600; PMID: 21806915 SO - BJU International. 104(4):534-9, 2009 Aug AS - BJU Int. 104(4):534-9, 2009 Aug NJ - BJU international PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - dcu, 100886721 IO - BJU Int. SB - Index Medicus CP - England MH - Aged MH - Erectile Dysfunction/pc [Prevention & Control] MH - Humans MH - Italy MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - Prospective Studies MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotics MH - Treatment Outcome MH - Urinary Incontinence/pc [Prevention & Control] AB - OBJECTIVE: To compare the functional results of two contemporary series of patients with clinically localized prostate cancer treated by robot-assisted laparoscopic prostatectomy (RALP) or retropubic radical prostatectomy (RRP). AB - PATIENTS AND METHODS: This was a non-randomized prospective comparative study of all patients undergoing RALP or RRP for clinically localized prostate cancer at our institution from February 2006 to April 2007. AB - RESULTS: We enrolled 105 patients in the RRP and 103 in the RALP group; the two groups were comparable for all clinical and pathological variables, except median age. For RRP and RALP the respective median operative duration was 135 and 185 min (P < 0.001), the intraoperative blood loss 500 and 300 mL (P < 0.001) and postoperative transfusion rates 14% and 1.9% (P < 0.01). There were complications in 9.7% and 10.4% of the patients (P = 0.854) after RRP and RALP, respectively; the positive surgical margin rates in pT2 cancers were 12.2% and 11.7% (P = 0.70). For urinary continence, 41% of patients having RRP and 68.9% of those having RALP were continent at catheter removal (P < 0.001). The 12-month continence rates were 88% after RRP and 97% after RALP (P = 0.01), with the mean time to continence being 75 and 25 days (P < 0.001), respectively. At the 12-month follow-up, 20 of 41 patients having bilateral nerve-sparing RRP (49%) and 52 of 64 having bilateral nerve-sparing RALP (81%) (P < 0.001) had recovery of erectile function. AB - CONCLUSIONS: RALP offers better results than RRP in terms of urinary continence and erectile function recovery, with similar positive surgical margin rates. ES - 1464-410X IL - 1464-4096 DI - BJU8419 DO - https://dx.doi.org/10.1111/j.1464-410X.2009.08419.x PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 19281468 [pubmed] ID - BJU8419 [pii] ID - 10.1111/j.1464-410X.2009.08419.x [doi] PP - ppublish LG - English EP - 20090305 DP - 2009 Aug DC - 20090811 EZ - 2009/03/14 09:00 DA - 2009/09/04 06:00 DT - 2009/03/14 09:00 YR - 2009 ED - 20090903 RD - 20110915 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19281468 <468. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19473064 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ploussard G AU - Xylinas E AU - Paul A AU - Gillion N AU - Salomon L AU - Allory Y AU - Vordos D AU - Hoznek A AU - Yiou R AU - Abbou CC AU - de la Taille A FA - Ploussard, Guillaume FA - Xylinas, Evanguelos FA - Paul, Alexandre FA - Gillion, Norman FA - Salomon, Laurent FA - Allory, Yves FA - Vordos, Dimitri FA - Hoznek, Andreas FA - Yiou, Rene FA - Abbou, Claude-Clement FA - de la Taille, Alexandre IN - Ploussard, Guillaume. Department of Urology, CHU Henri Mondor, Creteil, France. TI - Is robot assistance affecting operating room time compared with pure retroperitoneal laparoscopic radical prostatectomy?. SO - Journal of Endourology. 23(6):939-43, 2009 Jun AS - J Endourol. 23(6):939-43, 2009 Jun NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy MH - Lymph Node Excision MH - Male MH - Middle Aged MH - *Operating Rooms MH - Patient Care MH - Postoperative Complications/et [Etiology] MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - *Retroperitoneal Space/su [Surgery] MH - *Robotics/mt [Methods] MH - Time Factors AB - PURPOSE: To compare operating room times between retroperitoneal robot-assisted laparoscopic radical prostatectomy (RALRP) and pure retroperitoneal laparoscopic radical prostatectomy (LRP). AB - PATIENTS AND METHODS: From March 2007 to April 2008, 288 patients underwent an extraperitoneal LRP in our institution. Eighty-three LRPs were performed with robot assistance using the da Vinci Surgical System (RALRP) whereas 205 pure LRPs were performed. Operating room times were compared between the two groups. AB - RESULTS: Both groups were statistically equal concerning age (P = 0.95), body mass index (P = 0.52), prostate-specific antigen level (P = 0.40), prostate volume (P = 0.49), clinical stage (P = 0.11), and Gleason score on biopsy (P = 0.57). Total operating room time was not significantly different between the two groups (223.6 vs 215.7 minutes in LRP and RALRP groups, respectively; P = 0.23). Mean patient installation was longer in the RALRP group (33.2 vs 24.0 minutes, P < 0.01). Mean operative time was significantly shorter by about 20 minutes in the RALRP group (145.6 vs 164.7 minutes, P < 0.01). Mean estimated blood loss was significantly lower in the RALRP group (469 mL vs 889 mL in the LRP group, P < 0.01). No statistical differences were observed regarding hospital stay, bladder catheterization, and complication rate between the two groups. AB - CONCLUSION: Occupation times of the operating room are equivalent during pure retroperitoneal LRP and RALRP. For a trained team performing four procedures per week, the use of the robot for LRP with no lymph node dissection decreases actual operative time at the expense of an increase in installation time, compared with pure laparoscopy. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2008.0521 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 19473064 [pubmed] ID - 10.1089/end.2008.0521 [doi] PP - ppublish LG - English DP - 2009 Jun DC - 20090605 EZ - 2009/05/29 09:00 DA - 2009/08/19 09:00 DT - 2009/05/29 09:00 YR - 2009 ED - 20090818 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19473064 <469. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19473061 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Gupta NP AU - Mukherjee S AU - Nayyar R AU - Hemal AK AU - Kumar R FA - Gupta, Narmada P FA - Mukherjee, Satyadip FA - Nayyar, Rishi FA - Hemal, Ashok Kumar FA - Kumar, Rajeev IN - Gupta, Narmada P. Department of Urology, All India Institute of Medical Sciences, New Delhi, India. narmadagupta@gmail.com TI - Transmesocolic robot-assisted pyeloplasty: single center experience. SO - Journal of Endourology. 23(6):945-8, 2009 Jun AS - J Endourol. 23(6):945-8, 2009 Jun NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adolescent MH - Adult MH - Child MH - Female MH - Humans MH - Male MH - *Mesocolon/su [Surgery] MH - Middle Aged MH - Postoperative Care MH - Preoperative Care MH - *Reconstructive Surgical Procedures/mt [Methods] MH - *Robotics/mt [Methods] MH - Urography AB - PURPOSE: To demonstrate the technical feasibility of the transmesocolic approach of robotic pyeloplasty for left ureteropelvic junction obstruction (UPJO). AB - PATIENTS AND METHODS: Between July 2006 and December 2007, 60 patients underwent robot-assisted pyeloplasty that included 33 cases on the right side and 27 cases on the left side. Of the 27 left-side cases, 24 were performed using a transmesocolic approach. Three left-side surgeries were performed by mobilizing the colon because of associated accessory vessel and renal calculi. A pure robot-assisted dismembered reduction pyeloplasty with excision of the ureteropelvic junction was performed in all cases. AB - RESULTS: The mean operative time was 125.33 minutes. The time to perform the anastomosis was 43.58 minutes, and mean blood loss 38.7 mL. Average hospital stay was 2.5 days, and the drain was removed within 48 hours. One patient had prolonged drainage with fever because of a misplaced ureteral stent. Of the 24 patients, 23 were followed for 1 year and 1 was lost to follow-up. No patient demonstrated clinical or radiographic evidence of repeated obstruction. AB - CONCLUSION: In the transmesocolic approach, mobilization of the colon is not necessary, and the UPJO can be approached directly after incising the mesocolon. This approach is safe and feasible in patients with a thin mesentry and when extensive mobilization of the kidney is not needed for any associated problems. The technique is highly effective with durable success rates similar to those of open surgery. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2008.0430 PT - Clinical Trial PT - Journal Article ID - 19473061 [pubmed] ID - 10.1089/end.2008.0430 [doi] PP - ppublish LG - English DP - 2009 Jun DC - 20090605 EZ - 2009/05/29 09:00 DA - 2009/08/19 09:00 DT - 2009/05/29 09:00 YR - 2009 ED - 20090818 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19473061 <470. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19253902 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Caynak B AU - Sagbas E AU - Onan B AU - Onan IS AU - Sanisoglu I AU - Akpinar B FA - Caynak, Baris FA - Sagbas, Ertan FA - Onan, Burak FA - Onan, Ismihan Selen FA - Sanisoglu, Ilhan FA - Akpinar, Belhhan IN - Caynak, Baris. Department of Cardiovascular Surgery, Istanbul Bilim University, Florence Nightingale Hospital, Istanbul, Turkey. caynakbaris@hotmail.com TI - Robotically enhanced coronary artery bypass grafting: the feasibility and clinical outcome of 196 procedures. SO - The International Journal Of Medical Robotics + Computer Assisted Surgery: MRCAS. 5(2):170-7, 2009 Jun AS - Int J Med Robot. 5(2):170-7, 2009 Jun NJ - The international journal of medical robotics + computer assisted surgery : MRCAS PI - Journal available in: Print PI - Citation processed from: Internet JC - 101250764 IO - Int J Med Robot SB - Index Medicus CP - England MH - Adult MH - Aged MH - Coronary Artery Bypass/ae [Adverse Effects] MH - Coronary Artery Bypass/is [Instrumentation] MH - *Coronary Artery Bypass/mt [Methods] MH - Coronary Artery Bypass, Off-Pump/ae [Adverse Effects] MH - Coronary Artery Bypass, Off-Pump/is [Instrumentation] MH - Coronary Artery Bypass, Off-Pump/mt [Methods] MH - Coronary Artery Disease/su [Surgery] MH - Female MH - Humans MH - Male MH - Mammary Arteries/su [Surgery] MH - Middle Aged MH - Postoperative Complications/et [Etiology] MH - Robotics/is [Instrumentation] MH - *Robotics/mt [Methods] MH - Surgery, Computer-Assisted/is [Instrumentation] MH - *Surgery, Computer-Assisted/mt [Methods] MH - Treatment Outcome AB - BACKGROUND: The aim of this study was to assess the feasibility of robotically enhanced myocardial revascularization and to present the clinical outcome of 196 patients. AB - METHODS: All internal thoracic arteries were harvested with the aid of a robotic surgical system. While off-pump revascularization techniques were mostly used, peripheral cardiopulmonary bypass was needed in some cases with multivessel disease. AB - RESULTS: A single (n = 118) or multivessel (n = 74) coronary revascularization was performed. Four patients had to be converted to median sternotomy. There was no operative mortality. Follow-up was complete in 88% (n = 169) patients. The rate of freedom from ischaemic symptoms was 98.2% at mean 22 +/- 3 months. Graft patency was 96.4% (81/84). AB - CONCLUSIONS: By increasing surgical capabilities, robotically enhanced CABG in single or multivessel coronary disease was safe, effective and reasonable. It can be an alternative approach to percutaneous methods and conventional surgical techniques, or even used in acute coronary events. ES - 1478-596X IL - 1478-5951 DO - https://dx.doi.org/10.1002/rcs.244 PT - Clinical Trial PT - Journal Article ID - 19253902 [pubmed] ID - 10.1002/rcs.244 [doi] PP - ppublish LG - English DP - 2009 Jun DC - 20090520 EZ - 2009/03/04 09:00 DA - 2009/08/11 09:00 DT - 2009/03/04 09:00 YR - 2009 ED - 20090810 RD - 20090520 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19253902 <471. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19165497 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Muller-Stich BP AU - Reiter MA AU - Mehrabi A AU - Wente MN AU - Fischer L AU - Koninger J AU - Gutt CN FA - Muller-Stich, B P FA - Reiter, M A FA - Mehrabi, A FA - Wente, M N FA - Fischer, L FA - Koninger, J FA - Gutt, C N IN - Muller-Stich, B P. Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany. TI - No relevant difference in quality of life and functional outcome at 12 months' follow-up-a randomised controlled trial comparing robot-assisted versus conventional laparoscopic Nissen fundoplication. SO - Langenbecks Archives of Surgery. 394(3):441-6, 2009 May AS - Langenbecks Arch Surg. 394(3):441-6, 2009 May NJ - Langenbeck's archives of surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - cw4, 9808285 IO - Langenbecks Arch Surg SB - Index Medicus CP - Germany MH - Chi-Square Distribution MH - Female MH - *Fundoplication/mt [Methods] MH - *Gastroesophageal Reflux/su [Surgery] MH - Humans MH - *Laparoscopy MH - Male MH - Middle Aged MH - Pilot Projects MH - *Quality of Life MH - *Recovery of Function MH - *Robotics MH - Statistics, Nonparametric MH - Surveys and Questionnaires MH - Treatment Outcome AB - PURPOSE: The present randomised pilot trial was designed to compare robot-assisted (RALF) and conventional laparoscopic fundoplication (CLF) focussing on post-operative quality of life (QOL) and functional outcome. Any long-lasting advantages for patients in this regard could be a justification for the use of RALF for the treatment of gastroesophageal reflux disease (GERD). AB - METHODS: Forty patients with GERD were randomised to either RALF or to CLF. During a follow-up period of 12 months, patients' QOL and functional outcome were investigated using disease-specific questionnaires. AB - RESULTS: There were no significant differences in the mean QOL (1.3 versus 1.1; P = 0.374) and functional outcome (1.27 versus 1.3; P = 0.913) between both groups. Minor side effects such as bloating and persistent diarrhoea were present in four patients of each group. AB - CONCLUSION: The present study did not show any benefit for RALF over CLF regarding QOL and functional outcome at 12 months' follow-up. ES - 1435-2451 IL - 1435-2443 DO - https://dx.doi.org/10.1007/s00423-008-0446-8 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 19165497 [pubmed] ID - 10.1007/s00423-008-0446-8 [doi] PP - ppublish PH - 2008/11/05 [received] PH - 2008/11/28 [accepted] LG - English EP - 20090123 DP - 2009 May DC - 20090320 EZ - 2009/01/24 09:00 DA - 2009/08/06 09:00 DT - 2009/01/24 09:00 YR - 2009 ED - 20090805 RD - 20161020 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19165497 <472. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19290486 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Baik SH AU - Kwon HY AU - Kim JS AU - Hur H AU - Sohn SK AU - Cho CH AU - Kim H FA - Baik, Seung Hyuk FA - Kwon, Hye Youn FA - Kim, Jin Soo FA - Hur, Hyuk FA - Sohn, Seung Kook FA - Cho, Chang Hwan FA - Kim, Hoguen IN - Baik, Seung Hyuk. Department of Surgery, Yonsei University College of Medicine, Shinchon-dong, Seodaemun-ku, Seoul, Korea. whitenoja@yuhs.ac TI - Robotic versus laparoscopic low anterior resection of rectal cancer: short-term outcome of a prospective comparative study. CM - Comment in: Ann Surg Oncol. 2009 Jun;16(6):1451-3; PMID: 19357928 SO - Annals of Surgical Oncology. 16(6):1480-7, 2009 Jun AS - Ann Surg Oncol. 16(6):1480-7, 2009 Jun NJ - Annals of surgical oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - b9r, 9420840 IO - Ann. Surg. Oncol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - *Colectomy/mt [Methods] MH - Female MH - Humans MH - Laparoscopy MH - Male MH - Middle Aged MH - Prospective Studies MH - Randomized Controlled Trials as Topic MH - *Rectal Neoplasms/su [Surgery] MH - Robotics MH - Treatment Outcome AB - BACKGROUND: The aim of this study is to compare the short-term results between robotic-assisted low anterior resection (R-LAR), using the da Vinci Surgical System, and standard laparoscopic low anterior resection (L-LAR) in rectal cancer patients. AB - METHODS: 113 patients were assigned to receive either R-LAR (n = 56) or L-LAR (n = 57) between April 2006 and September 2007. Patient characteristics, perioperative clinical results, complications, and pathologic details were compared between the groups. Moreover, macroscopic grading of the specimen was evaluated. AB - RESULTS: Patient characteristics were not significantly different between the groups. The mean operation time was 190.1 +/- 45.0 min in the R-LAR group and 191.1 +/- 65.3 min in the L-LAR group (P = 0.924). The conversion rate was 0.0% in the R-LAR groups and 10.5% in the L-LAR group (P = 0.013). The serious complication rate was 5.4% in the R-LAR group and 19.3% in the L-LAR group (P = 0.025). The specimen quality was acceptable in both groups. However, the mesorectal grade was complete (n = 52) and nearly complete (n = 4) in the R-LAR group and complete (n = 43), nearly complete (n = 12), and incomplete (n = 2) in the L-LAR group (P = 0.033). AB - CONCLUSION: R-LAR was performed safely and effectively, using the da Vinci Surgical System. The use of the system resulted in acceptable perioperative outcomes compared to L-LAR. ES - 1534-4681 IL - 1068-9265 DO - https://dx.doi.org/10.1245/s10434-009-0435-3 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 19290486 [pubmed] ID - 10.1245/s10434-009-0435-3 [doi] PP - ppublish PH - 2008/08/11 [received] PH - 2008/11/09 [accepted] PH - 2008/11/08 [revised] LG - English EP - 20090317 DP - 2009 Jun DC - 20090505 EZ - 2009/03/18 09:00 DA - 2009/06/19 09:00 DT - 2009/03/18 09:00 YR - 2009 ED - 20090618 RD - 20090505 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19290486 <473. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19335214 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - McGee SM AU - Routh JC AU - Pereira CW AU - Gettman MT FA - McGee, Shawn M FA - Routh, Jonathan C FA - Pereira, Claudio W FA - Gettman, Matthew T IN - McGee, Shawn M. Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA. TI - Minimal contamination of the human peritoneum after transvesical incision. SO - Journal of Endourology. 23(4):659-63, 2009 Apr AS - J Endourol. 23(4):659-63, 2009 Apr NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Body Fluids/mi [Microbiology] MH - Humans MH - Male MH - Middle Aged MH - *Peritoneum/mi [Microbiology] MH - *Urinary Bladder/su [Surgery] AB - BACKGROUND AND PURPOSE: The recent literature has questioned the infectious risk of natural orifice translumenal endoscopic surgery (NOTES). The need for a clean portal of entry may be important to minimize peritoneal contamination after NOTES. Our study examines the resultant microbial contamination of the human peritoneum after transvesical incision and exposure of the abdomen to bladder contents during robot-assisted laparoscopic prostatectomy (RALP) to better understand the potential for infection in transvesical NOTES. AB - PATIENTS AND METHODS: Sixty consecutive men undergoing RALP for clinically localized prostate adenocarcinoma from January to May 2008 were prospectively studied as part of a database approved by an Institutional Review Board. The patient's preoperative urine microscopy values, complete blood cell count, and prostate-specific antigen (PSA) levels were recorded, along with the total length of time the cystotomy was open to the peritoneum. Intraoperative samplings of peritoneal fluid were collected before and after transvesical incision and sent for anaerobic, aerobic and fungal cultures. AB - RESULTS: Patients undergoing RALP had peritoneal exposure after transvesical incision for an average of 118 minutes. Five of 60 (8.3%) patients had evidence of novel aerobic bacterial contamination of the peritoneum after RALP. No patient had a positive anaerobic culture or fungal culture from the peritoneum. Preoperative serum leukocyte and PSA levels were elevated in patients with peritoneal contamination (P < 0.05). Remaining clinicopathologic features, total operative time, or open cystotomy time did not predict peritoneal contamination. AB - CONCLUSION: Prolonged peritoneal exposure to bladder contents demonstrates minimal contamination of the abdominal cavity and is without postoperative infectious significance. This study may overestimate bacterial contamination via the bladder during RALP, because the specific bacteria seen may have originated from the seminal or prostatic fluid during prostatectomy. Transvesical incision would effectively be a clean portal of entry for NOTES with its low rate of peritoneal contamination. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2008.0418 PT - Clinical Trial PT - Journal Article ID - 19335214 [pubmed] ID - 10.1089/end.2008.0418 [doi] PP - ppublish LG - English DP - 2009 Apr DC - 20090410 EZ - 2009/04/02 09:00 DA - 2009/06/18 09:00 DT - 2009/04/02 09:00 YR - 2009 ED - 20090617 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19335214 <474. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19406338 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hoffmann U AU - Bamberg F AU - Chae CU AU - Nichols JH AU - Rogers IS AU - Seneviratne SK AU - Truong QA AU - Cury RC AU - Abbara S AU - Shapiro MD AU - Moloo J AU - Butler J AU - Ferencik M AU - Lee H AU - Jang IK AU - Parry BA AU - Brown DF AU - Udelson JE AU - Achenbach S AU - Brady TJ AU - Nagurney JT FA - Hoffmann, Udo FA - Bamberg, Fabian FA - Chae, Claudia U FA - Nichols, John H FA - Rogers, Ian S FA - Seneviratne, Sujith K FA - Truong, Quynh A FA - Cury, Ricardo C FA - Abbara, Suhny FA - Shapiro, Michael D FA - Moloo, Jamaluddin FA - Butler, Javed FA - Ferencik, Maros FA - Lee, Hang FA - Jang, Ik-Kyung FA - Parry, Blair A FA - Brown, David F FA - Udelson, James E FA - Achenbach, Stephan FA - Brady, Thomas J FA - Nagurney, John T IN - Hoffmann, Udo. Cardiac MR PET CT Program, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA. uhoffmann@partners.org TI - Coronary computed tomography angiography for early triage of patients with acute chest pain: the ROMICAT (Rule Out Myocardial Infarction using Computer Assisted Tomography) trial. CM - Comment in: J Am Coll Cardiol. 2009 May 5;53(18):1651-2; PMID: 19406339 CM - Comment in: Curr Cardiol Rep. 2011 Feb;13(1):6-8; PMID: 20890687 SO - Journal of the American College of Cardiology. 53(18):1642-50, 2009 May 05 AS - J Am Coll Cardiol. 53(18):1642-50, 2009 May 05 NJ - Journal of the American College of Cardiology PI - Journal available in: Print PI - Citation processed from: Internet JC - h50, 8301365 IO - J. Am. Coll. Cardiol. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747766 OI - Source: NLM. NIHMS114746 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - *Acute Coronary Syndrome/di [Diagnosis] MH - Acute Coronary Syndrome/pp [Physiopathology] MH - Acute Disease MH - California MH - *Chest Pain/di [Diagnosis] MH - Chest Pain/pp [Physiopathology] MH - Confidence Intervals MH - Coronary Angiography/mt [Methods] MH - *Coronary Angiography MH - Diagnosis, Differential MH - Emergency Service, Hospital/sn [Statistics & Numerical Data] MH - Female MH - Humans MH - Male MH - Middle Aged MH - Odds Ratio MH - Prospective Studies MH - ROC Curve MH - Risk Factors MH - Sensitivity and Specificity MH - Single-Blind Method MH - Time Factors MH - *Tomography, X-Ray Computed MH - *Triage/sn [Statistics & Numerical Data] AB - OBJECTIVES: This study was designed to determine the usefulness of coronary computed tomography angiography (CTA) in patients with acute chest pain. AB - BACKGROUND: Triage of chest pain patients in the emergency department remains challenging. AB - METHODS: We used an observational cohort study in chest pain patients with normal initial troponin and nonischemic electrocardiogram. A 64-slice coronary CTA was performed before admission to detect coronary plaque and stenosis (>50% luminal narrowing). Results were not disclosed. End points were acute coronary syndrome (ACS) during index hospitalization and major adverse cardiac events during 6-month follow-up. AB - RESULTS: Among 368 patients (mean age 53 +/- 12 years, 61% men), 31 had ACS (8%). By coronary CTA, 50% of these patients were free of coronary artery disease (CAD), 31% had nonobstructive disease, and 19% had inconclusive or positive computed tomography for significant stenosis. Sensitivity and negative predictive value for ACS were 100% (n = 183 of 368; 95% confidence interval [CI]: 98% to 100%) and 100% (95% CI: 89% to 100%), respectively, with the absence of CAD and 77% (95% CI: 59% to 90%) and 98% (n = 300 of 368, 95% CI: 95% to 99%), respectively, with significant stenosis by coronary CTA. Specificity of presence of plaque and stenosis for ACS were 54% (95% CI: 49% to 60%) and 87% (95% CI: 83% to 90%), respectively. Only 1 ACS occurred in the absence of calcified plaque. Both the extent of coronary plaque and presence of stenosis predicted ACS independently and incrementally to Thrombolysis In Myocardial Infarction risk score (area under curve: 0.88, 0.82, vs. 0.63, respectively; all p < 0.0001). AB - CONCLUSIONS: Fifty percent of patients with acute chest pain and low to intermediate likelihood of ACS were free of CAD by computed tomography and had no ACS. Given the large number of such patients, early coronary CTA may significantly improve patient management in the emergency department. ES - 1558-3597 IL - 0735-1097 DI - S0735-1097(09)00541-5 DO - https://dx.doi.org/10.1016/j.jacc.2009.01.052 PT - Clinical Trial PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't ID - 19406338 [pubmed] ID - S0735-1097(09)00541-5 [pii] ID - 10.1016/j.jacc.2009.01.052 [doi] ID - PMC2747766 [pmc] ID - NIHMS114746 [mid] PP - ppublish PH - 2008/10/31 [received] PH - 2008/12/19 [revised] PH - 2009/01/12 [accepted] GI - No: R01 HL080053-02 Organization: (HL) *NHLBI NIH HHS* Country: United States No: T32HL076136 Organization: (HL) *NHLBI NIH HHS* Country: United States No: T32 HL076136 Organization: (HL) *NHLBI NIH HHS* Country: United States No: R01 HL080053 Organization: (HL) *NHLBI NIH HHS* Country: United States No: R01 HL080053-03 Organization: (HL) *NHLBI NIH HHS* Country: United States No: R01 HL080053-01A1 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English DP - 2009 May 05 DC - 20090501 EZ - 2009/05/02 09:00 DA - 2009/06/10 09:00 DT - 2009/05/02 09:00 YR - 2009 ED - 20090609 RD - 20161122 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19406338 <475. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19394503 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Cho JE AU - Shim JK AU - Chang JH AU - Oh YJ AU - Kil HK AU - Rha KH AU - Kwak YL FA - Cho, Jang Eun FA - Shim, Jae Kwang FA - Chang, Jae Hyun FA - Oh, Young Jun FA - Kil, Hae Keum FA - Rha, Koon Ho FA - Kwak, Young Lan IN - Cho, Jang Eun. Department of Anesthesiology and Pain Medicine, and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea. TI - Effect of nicardipine on renal function after robot-assisted laparoscopic radical prostatectomy. SO - Urology. 73(5):1056-60, 2009 May AS - Urology. 73(5):1056-60, 2009 May NJ - Urology PI - Journal available in: Print PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Aged MH - Creatinine/bl [Blood] MH - Follow-Up Studies MH - *Glomerular Filtration Rate/de [Drug Effects] MH - Humans MH - Infusions, Intravenous MH - Kidney Function Tests MH - Male MH - Middle Aged MH - *Nicardipine/tu [Therapeutic Use] MH - Perioperative Care/mt [Methods] MH - Pneumoperitoneum, Artificial MH - Postoperative Complications/pc [Prevention & Control] MH - Probability MH - Prospective Studies MH - Prostatectomy/is [Instrumentation] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Reference Values MH - Renal Insufficiency/pc [Prevention & Control] MH - Risk Assessment MH - *Robotics MH - Statistics, Nonparametric MH - Treatment Outcome MH - Vasodilator Agents/tu [Therapeutic Use] AB - OBJECTIVES: To investigate the renoprotective effect of nicardipine in patients undergoing robot-assisted laparoscopic radical prostatectomy (RALRP) in a prospective trial. Superior visualization of the increasingly performed RALRP requires pneumoperitoneum and extreme head-down tilt, both of which are associated with a decrease in postoperative renal function. Nicardipine causes preferential dilation of the renal arterioles and attenuates renal dysfunction after cardiac surgery. AB - METHODS: After we obtained institutional review board approval, we randomly treated 100 patients undergoing RALRP with a continuous infusion of nicardipine at a rate of 0.5 microg/kg/min (nicardipine group, n = 50) or with normal saline (control group, n = 50) during surgery. We measured the serum creatinine (Cr) level and estimated glomerular filtration rate (eGFR) 1 day before surgery and the first and third postoperative days (POD 1 and 3, respectively). AB - RESULTS: Patients' characteristics and operative data were similar between groups. The serum Cr was significantly higher and the eGFR was significantly lower in the control group at POD 1. The number of patients having renal insufficiency (eGFR < 60 mL/min/1.73 m(2)) and abnormal serum creatinine level (>1.4 mg/dL) was significantly greater in the control group (9 vs 1, and 4 vs none, respectively) at POD 1. AB - CONCLUSIONS: Continuous infusion of low-dose nicardipine during RALRP seems to offset the deleterious effects of inevitable pneumoperitoneum and extreme head-down tilt on renal function in preserving the eGFR and attenuating the development of renal insufficiency in the immediate postoperative period. RN - 0 (Vasodilator Agents) RN - AYI8EX34EU (Creatinine) RN - CZ5312222S (Nicardipine) ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(08)01523-9 DO - https://dx.doi.org/10.1016/j.urology.2008.08.490 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 19394503 [pubmed] ID - S0090-4295(08)01523-9 [pii] ID - 10.1016/j.urology.2008.08.490 [doi] PP - ppublish PH - 2008/05/14 [received] PH - 2008/07/10 [revised] PH - 2008/08/25 [accepted] LG - English DP - 2009 May DC - 20090427 EZ - 2009/04/28 09:00 DA - 2009/06/06 09:00 DT - 2009/04/28 09:00 YR - 2009 ED - 20090604 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19394503 <476. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19399932 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Filipovic N AU - Cvetkovic A AU - Isailovic V AU - Matovic Z AU - Rosic M AU - Kojic M FA - Filipovic, Nenad FA - Cvetkovic, Aleksandar FA - Isailovic, Velibor FA - Matovic, Zoran FA - Rosic, Mirko FA - Kojic, Milos IN - Filipovic, Nenad. Faculty of Mechanical Engineering, University of Kragujevac, S Janjica 6, Kragujevac, Serbia. fica@kg.ac.rs TI - Computer simulation of flow and mixing at the duodenal stump after gastric resection. SO - World Journal of Gastroenterology. 15(16):1990-8, 2009 Apr 28 AS - World J Gastroenterol. 15(16):1990-8, 2009 Apr 28 NJ - World journal of gastroenterology PI - Journal available in: Print PI - Citation processed from: Internet JC - 100883448 IO - World J. Gastroenterol. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675090 SB - Index Medicus CP - United States MH - *Computer Simulation MH - Duodenum/ah [Anatomy & Histology] MH - Duodenum/me [Metabolism] MH - *Duodenum/su [Surgery] MH - Gastrectomy/ae [Adverse Effects] MH - Gastrectomy/mt [Methods] MH - *Gastrectomy MH - *Gastroenterostomy MH - Humans MH - Manometry/is [Instrumentation] MH - Manometry/mt [Methods] MH - Placebos MH - Pressure MH - Prospective Studies AB - AIM: To investigate the flow and mixing at the duodenal stump after gastric resection, a computer simulation was implemented. AB - METHODS: Using the finite element method, two different Billroth II procedure cases (A and B) were modeled. Case A was defined with a shorter and almost straight duodenal section, while case B has a much longer and curved duodenal section. Velocity, pressure and food concentration distribution were determined and the numerical results were compared with experimental observations. AB - RESULTS: The pressure distribution obtained by numerical simulation was in the range of the recorded experimental results. Case A had a more favorable pressure distribution in comparison with case B. However, case B had better performance in terms of food transport because of more continual food distribution, as well as better emptying of the duodenal section. AB - CONCLUSION: This study offers insight into the transport process within the duodenal stump section after surgical intervention, which can be useful for future patient-specific predictions of a surgical outcome. RN - 0 (Placebos) ES - 2219-2840 IL - 1007-9327 PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 19399932 [pubmed] ID - PMC2675090 [pmc] PP - ppublish LG - English DP - 2009 Apr 28 DC - 20090428 EZ - 2009/04/29 09:00 DA - 2009/05/27 09:00 DT - 2009/04/29 09:00 YR - 2009 ED - 20090526 RD - 20151022 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19399932 <477. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19223694 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Eljamel MS FA - Eljamel, M S IN - Eljamel, M S. Department of Neurosurgery, Ninewells Hospital and Medical School, Dundee, UK. m.s.eljamel@dundee.ac.uk TI - Robotic neurological surgery applications: accuracy and consistency or pure fantasy?. SO - Stereotactic & Functional Neurosurgery. 87(2):88-93, 2009 AS - Stereotact Funct Neurosurg. 87(2):88-93, 2009 NJ - Stereotactic and functional neurosurgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - sfn, 8902881 IO - Stereotact Funct Neurosurg SB - Index Medicus CP - Switzerland MH - *Brain Diseases/su [Surgery] MH - Brain Neoplasms/su [Surgery] MH - Depressive Disorder/su [Surgery] MH - Female MH - Gyrus Cinguli/su [Surgery] MH - Humans MH - Male MH - Middle Aged MH - *Minimally Invasive Surgical Procedures/is [Instrumentation] MH - Minimally Invasive Surgical Procedures/mt [Methods] MH - Minimally Invasive Surgical Procedures/st [Standards] MH - Neuronavigation/is [Instrumentation] MH - *Neuronavigation/mt [Methods] MH - *Neuronavigation/st [Standards] MH - Parkinson Disease/su [Surgery] MH - Reproducibility of Results MH - Robotics/is [Instrumentation] MH - Robotics/mt [Methods] MH - Robotics/st [Standards] MH - Software MH - Subthalamic Nucleus/su [Surgery] MH - Thalamic Nuclei/su [Surgery] AB - INTRODUCTION: Minimally invasive surgery was born out of recent advances in neuroimaging and stereotaxy, and the scale of future neurosurgical procedures will soon be so small that it will not be possible for the unassisted surgeons. Hence, neurosurgical robotics is a natural evolution in this field. The aim of this study was to evaluate the performance of a new robotic system in a wide range of neurosurgical applications. AB - METHODS: Patients undergoing image-guided surgical procedures were recruited to participate in this prospective ethically approved study from 2005. The PathFinder (Prosurgics, UK) is a neurosurgical robotic system with 6 degrees of freedom. It uses a fiducial system that is automatically detectable by the planning software and a camera system embedded in the robot's head. The registration procedure was performed automatically by photographing the fiducials from different angles. The robot then aligns its end-effector and tool holder along the specified path for the surgeon to pass the probe to the target. We recruited 37 consecutive patients to test the application accuracy and consistency of the system using three different fiducial fixation mechanisms: a double adhesive fixed to the skin, an ECG lead dot fixed to the skin, and a registration plate fixed to the skull. AB - RESULTS: Out of 37 consecutive patients, 17 were males and 20 were females, with a mean age of 46.6 years. The procedures were: transsphenoidal in 8, malignant tumour biopsies in 3 and resections in 5, benign tumour excisions in 6 and functional procedures in 15 [6 bilateral deep-brain stimulations (DBSs) of the subthalamic nucleus for Parkinson's disease, 3 bilateral anterior cingulotomies for depression, 3 bilateral DBSs of the ventral intermediate nucleus of the thalamus for tremor and 3 depth electrodes during epilepsy surgery]. We tested a total of 140 targets with an average of 3-4 targets per patient. The mean application accuracy was less than 1 mm and the application accuracy was consistent in all targets in the same patient. AB - CONCLUSIONS: This robotic system was very accurate and consistent in practice as long as the robot had achieved acceptable registration. AB - Copyright (c) 2009 S. Karger AG, Basel. ES - 1423-0372 IL - 1011-6125 DI - 000202974 DO - https://dx.doi.org/10.1159/000202974 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Technical Report PT - Validation Studies ID - 19223694 [pubmed] ID - 000202974 [pii] ID - 10.1159/000202974 [doi] PP - ppublish LG - English EP - 20090218 DP - 2009 DC - 20090326 EZ - 2009/02/19 09:00 DA - 2009/05/12 09:00 DT - 2009/02/19 09:00 YR - 2009 ED - 20090511 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19223694 <478. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19178174 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Guru KA AU - Perlmutter AE AU - Sheldon MJ AU - Butt ZM AU - Zhang S AU - Tan W AU - Wilding G AU - Kim HL AU - Mohler JL FA - Guru, Khurshid A FA - Perlmutter, Adam E FA - Sheldon, Matthew J FA - Butt, Zubair M FA - Zhang, Shaozeng FA - Tan, Wei FA - Wilding, Gregory FA - Kim, Hyung L FA - Mohler, James L IN - Guru, Khurshid A. Department of Urologic Oncology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA. khurshid.guru@roswellpark.org TI - Apical margins after robot-assisted radical prostatectomy: does technique matter?. SO - Journal of Endourology. 23(1):123-7, 2009 Jan AS - J Endourol. 23(1):123-7, 2009 Jan NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Demography MH - Humans MH - Male MH - Middle Aged MH - *Prostate/pa [Pathology] MH - *Prostate/su [Surgery] MH - *Prostatectomy/mt [Methods] MH - *Robotics AB - BACKGROUND AND PURPOSE: The apex is the most common site of an involved surgical margin after robot-assisted radical prostatectomy. We assessed the impact of two surgical techniques for dorsal vein control on surgical margins rates. AB - PATIENTS AND METHODS: From August 2005 to January 2008, 480 patients underwent robot-assisted radical prostatectomy at Roswell Park Cancer Institute. The Roswell Park Cancer Institute Quality Assurance robotic prostatectomy database was reviewed to identify all patients with prostate cancer at the apex on final pathologic evaluation. The rate of positive apical margins was compared between two surgical techniques. Group 1 consisted of 145 patients who underwent apical dissection after cold incision of the dorsal venous complex (DVC) without previous suture ligation, and group 2 consisted of 158 patients who underwent suture ligation of the DVC before apical dissection. AB - RESULTS: Of 480 patients, 303 (63%) patients had prostate cancer in the apex. Age, body mass index, prostate-specific antigen level, and clinical stage were similar in both groups. The overall apical positive margin rate was 5%. Group 1 patients had an apical positive margin rate of 2%, while group 2 patients had a positive margin rate of 8% (P = 0.02). Mean operative blood loss estimated by the attending anesthesiologist was 331 mL and 268 mL in group 1 and group 2, respectively (P = 0.044). One patient in group 1 needed blood transfusion. AB - CONCLUSIONS: Cold incision of the DVC before suture ligation reduces the rate of apical margin involvement during robot-assisted radical prostatectomy. ES - 1557-900X IL - 0892-7790 DI - 10.1089/end.2008.0398 DO - https://dx.doi.org/10.1089/end.2008.0398 PT - Clinical Trial PT - Journal Article ID - 19178174 [pubmed] ID - 10.1089/end.2008.0398 [doi] ID - 10.1089/end.2008.0398 [pii] PP - ppublish LG - English DP - 2009 Jan DC - 20090130 EZ - 2009/01/31 09:00 DA - 2009/05/07 09:00 DT - 2009/01/31 09:00 YR - 2009 ED - 20090506 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19178174 <479. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19115245 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hartmann J AU - Menenakos C AU - Ordemann J AU - Nocon M AU - Raue W AU - Braumann C FA - Hartmann, Jens FA - Menenakos, Charalambos FA - Ordemann, Juergen FA - Nocon, Marc FA - Raue, Wieland FA - Braumann, Chris IN - Hartmann, Jens. Department of General, Visceral, Vascular and Thoracic Surgery, Charite-Universitaetsmedizin Berlin, Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany. jens.hartmann@charite.de TI - Long-term results of quality of life after standard laparoscopic vs. robot-assisted laparoscopic fundoplications for gastro-oesophageal reflux disease. A comparative clinical trial. SO - The International Journal Of Medical Robotics + Computer Assisted Surgery: MRCAS. 5(1):32-7, 2009 Mar AS - Int J Med Robot. 5(1):32-7, 2009 Mar NJ - The international journal of medical robotics + computer assisted surgery : MRCAS PI - Journal available in: Print PI - Citation processed from: Internet JC - 101250764 IO - Int J Med Robot SB - Index Medicus CP - England MH - *Clinical Trials as Topic MH - Female MH - *Fundoplication/mt [Methods] MH - *Gastroesophageal Reflux/su [Surgery] MH - Humans MH - Laparoscopy/mt [Methods] MH - Laparoscopy/st [Standards] MH - *Laparoscopy MH - Male MH - *Quality of Life MH - *Robotics MH - Surveys and Questionnaires MH - Treatment Outcome AB - BACKGROUND: The role of telematic surgical approach in gastro-oesophageal reflux disease (GERD) is still unclear. AB - METHODS: The aim of the study is to assess disease specific symptoms and quality of life in patients with GERD treated with either traditional laparoscopic (TL) or robot-assisted fundoplication using the Da Vinci system (DV) in long-term follow-up. AB - RESULTS: Eighty patients underwent a fundoplication in 2003. Four years later all patients were given a standardized questionnaire and 59 (74%) replied. The TL group included 44 patients (18 male/26 female) and the DV group 15 patients (9 male/6 female); the mean operating time was 116 min for the TL group and 207 min for the DV group (p < 0.001). The mean GIQLI score was 106 points for TL and 107 points in the DV (p > 0.05). AB - CONCLUSIONS: Although a safe and feasible procedure, high functional costs of the Da Vinci system and longer operating time prevent this operation from being the standard surgical procedure for GERD. ES - 1478-596X IL - 1478-5951 DO - https://dx.doi.org/10.1002/rcs.228 PT - Comparative Study PT - Journal Article ID - 19115245 [pubmed] ID - 10.1002/rcs.228 [doi] PP - ppublish LG - English DP - 2009 Mar DC - 20090219 EZ - 2008/12/31 09:00 DA - 2009/04/30 09:00 DT - 2008/12/31 09:00 YR - 2009 ED - 20090429 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19115245 <480. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18401648 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Katsavelis D AU - Siu KC AU - Brown-Clerk B AU - Lee IH AU - Lee YK AU - Oleynikov D AU - Stergiou N FA - Katsavelis, Dimitrios FA - Siu, Ka-Chun FA - Brown-Clerk, Bernadette FA - Lee, Irene H FA - Lee, Yong Kwon FA - Oleynikov, Dmitry FA - Stergiou, Nick IN - Katsavelis, Dimitrios. HPER Biomechanics Lab, University of Nebraska at Omaha, Omaha, NE 68182-0216, USA. TI - Validated robotic laparoscopic surgical training in a virtual-reality environment. SO - Surgical Endoscopy. 23(1):66-73, 2009 Jan AS - Surg Endosc. 23(1):66-73, 2009 Jan NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adult MH - Clinical Competence MH - *Computer-Assisted Instruction MH - Female MH - Humans MH - *Laparoscopy MH - Male MH - *Motor Skills/ph [Physiology] MH - Practice (Psychology) MH - Reproducibility of Results MH - *Robotics MH - *Surgery, Computer-Assisted/ed [Education] MH - *User-Computer Interface MH - Young Adult AB - BACKGROUND: A robotic virtual-reality (VR) simulator has been developed to improve robot-assisted training for laparoscopic surgery and to enhance surgical performance in laparoscopic skills. The simulated VR training environment provides an effective approach to evaluate and improve surgical performance. This study presents our findings of the VR training environment for robotic laparoscopy. AB - METHODS: Eight volunteers performed two inanimate tasks in both the VR and the actual training environment. The tasks were bimanual carrying (BC) and needle passing (NP). For the BC task, the volunteers simultaneously transferred two plastic pieces in opposite directions five times consecutively. The same volunteers passed a surgical needle through six pairs of holes in the NP task. Both tasks require significant bimanual coordination that mimics actual laparoscopic skills. Data analysis included time to task completion, speed and distance traveled of the instrument tip, as well as range of motion of the subject's wrist and elbow of the right arm. Electromyography of the right wrist flexor and extensor were also analyzed. Paired t-tests and Pearson's r were used to explore the differences and correlations between the two environments. AB - RESULTS: There were no significant differences between the actual and the simulated VR environment with respect to the BC task, while there were significant differences in almost all dependent parameters for the NP task. Moderate to high correlations for most dependent parameters were revealed for both tasks. AB - CONCLUSIONS: Our data shows that the VR environment adequately simulated the BC task. The significant differences found for the NP task may be attributed to an oversimplification in the VR environment. However, they do point to the need for improvements in the complexity of our VR simulation. Further research work is needed to develop effective and reliable VR environments for robotic laparoscopic training. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-008-9894-z PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't ID - 18401648 [pubmed] ID - 10.1007/s00464-008-9894-z [doi] PP - ppublish PH - 2007/04/21 [received] PH - 2008/02/25 [accepted] PH - 2008/02/04 [revised] GI - No: K24HD047194 Organization: (HD) *NICHD NIH HHS* Country: United States LG - English EP - 20080410 DP - 2009 Jan DC - 20081230 EZ - 2008/04/11 09:00 DA - 2009/04/25 09:00 DT - 2008/04/11 09:00 YR - 2009 ED - 20090423 RD - 20081230 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18401648 <481. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18297349 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lin DW AU - Romanelli JR AU - Kuhn JN AU - Thompson RE AU - Bush RW AU - Seymour NE FA - Lin, David W FA - Romanelli, John R FA - Kuhn, Jay N FA - Thompson, Renee E FA - Bush, Ron W FA - Seymour, Neal E IN - Lin, David W. Department of Surgery, Baystate Medical Center, 759 Chestnut Street, Springfield, MA 01199, USA. TI - Computer-based laparoscopic and robotic surgical simulators: performance characteristics and perceptions of new users. SO - Surgical Endoscopy. 23(1):209-14, 2009 Jan AS - Surg Endosc. 23(1):209-14, 2009 Jan NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Attitude of Health Personnel MH - Clinical Competence MH - *Computer-Assisted Instruction/is [Instrumentation] MH - Curriculum MH - *General Surgery/ed [Education] MH - Human Engineering MH - Humans MH - *Laparoscopy MH - Motor Skills MH - Practice (Psychology) MH - Reproducibility of Results MH - *Robotics MH - *Suture Techniques/ed [Education] MH - *User-Computer Interface AB - BACKGROUND: This study aimed to define perceptions of the need and the value of new simulation devices for laparoscopic and robot-assisted surgery. The initial experience of surgeons using both robotic and nonrobotic laparoscopic simulators to perform an advanced laparoscopic skill was evaluated. AB - METHODS: At the 2006 Society of American Gastroesophageal Surgeons (SAGES) meeting, 63 Learning Center attendees used a new virtual reality robotic surgery simulator (SEP Robot) and either a computer-enhanced laparoscopic simulator (ProMIS) or a virtual reality simulator (SurgicalSIM). Demographic and training data were collected by an intake survey. Subjects then were assessed during one iteration of laparoscopic suturing and knot-tying on the SEP Robot and either the ProMIS or the SurgicalSIM. A posttask survey determined users' impressions of task realism, interface quality, and educational value. Performance data were collected and comparisons made between user-defined groups, different simulation platforms, and posttask survey responses. AB - RESULTS: The task completion rate was significantly greater for experts than for nonexperts on the virtual reality platforms (SurgicalSIM: 100% vs 36%; SEP Robot: 93% vs 63%; p < 0.05). Prior robot use was predictive of task completion on the SEP Robot, and nonexperts were more likely to complete the virtual reality task on the SEP Robot than on the SurgicalSIM. Experts performed better than nonexperts for all performance measures on the ProMIS. All the survey scores pertaining to realism except image quality were higher for the ProMIS than for either virtual reality trainer. AB - CONCLUSION: The task completion rate was the best discriminant of expert performance on both virtual reality platforms, whereas simulator metrics best discriminated expertise for the videoscopic platform. Similar comparisons for the virtual reality platforms were not feasible because of the low task completion rate for nonexperts. The added degrees of freedom associated with the robotic surgical simulator instruments facilitated completion of the task by nonexperts. All platforms were perceived as effective training tools. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-008-9805-3 PT - Clinical Trial PT - Journal Article ID - 18297349 [pubmed] ID - 10.1007/s00464-008-9805-3 [doi] PP - ppublish PH - 2007/04/21 [received] PH - 2008/01/19 [accepted] PH - 2007/09/10 [revised] LG - English EP - 20080223 DP - 2009 Jan DC - 20081230 EZ - 2008/02/26 09:00 DA - 2009/04/25 09:00 DT - 2008/02/26 09:00 YR - 2009 ED - 20090423 RD - 20081230 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18297349 <482. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19042929 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Martins Rua JF AU - Jatene FB AU - de Campos JR AU - Monteiro R AU - Tedde ML AU - Samano MN AU - Bernardo WM AU - Das-Neves-Pereira JC FA - Martins Rua, Joaquim Fernando FA - Jatene, Fabio Biscegli FA - de Campos, Jose Ribas Milanez FA - Monteiro, Rosangela FA - Tedde, Miguel Lia FA - Samano, Marcos Naoyuki FA - Bernardo, Wanderley M FA - Das-Neves-Pereira, Joao Carlos IN - Martins Rua, Joaquim Fernando. Department of Thoracic Surgery, University of Sao Paulo, Medical School, Heart Institute InCor, Clinics Hospital, Sao Paulo, Brazil. TI - Robotic versus human camera holding in video-assisted thoracic sympathectomy: a single blind randomized trial of efficacy and safety. SO - Interactive Cardiovascular & Thoracic Surgery. 8(2):195-9, 2009 Feb AS - Interact Cardiovasc Thorac Surg. 8(2):195-9, 2009 Feb NJ - Interactive cardiovascular and thoracic surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101158399 IO - Interact Cardiovasc Thorac Surg SB - Index Medicus CP - England MH - Adolescent MH - Adult MH - Female MH - Ganglionectomy/ae [Adverse Effects] MH - Ganglionectomy/is [Instrumentation] MH - *Ganglionectomy/mt [Methods] MH - Humans MH - *Hyperhidrosis/su [Surgery] MH - Male MH - Prospective Studies MH - *Robotics MH - Single-Blind Method MH - Surgery, Computer-Assisted/is [Instrumentation] MH - *Surgery, Computer-Assisted MH - Thoracic Surgery, Video-Assisted/ae [Adverse Effects] MH - *Thoracic Surgery, Video-Assisted MH - *Thoracoscopes MH - Time Factors MH - Treatment Outcome MH - Young Adult AB - Our objective is to compare surgical safety and efficacy between robotic and human camera control in video-assisted thoracic sympathectomy. A randomized-controlled-trial was performed. Surgical operation was VATS sympathectomy for hyperhidrosis. The trial compared a voice-controlled robot for holding the endoscopic camera robotic group (Ro) to human assisted group (Hu). Each group included 19 patients. Sympathectomy was achieved by electrodessication of the third ganglion. Operations were filmed and images stored. Two observers quantified the number of involuntary and inappropriate movements and how many times the camera was cleaned. Safety criteria were surgical accidents, pain and aesthetical results; efficacy criteria were: surgical and camera use duration, anhydrosis, length of hospitalization, compensatory hyperhidrosis and patient satisfaction. There was no difference between groups regarding surgical accidents, number of involuntary movements, pain, aesthetical results, general satisfaction, number of lens cleaning, anhydrosis, length of hospitalization, and compensatory hyperhidrosis. The number of contacts of the laparoscopic lens with mediastinal structures was lower in the Ro group (P<0.001), but the total and surgical length was longer in this group (P<0.001). Camera holding by a robotic arm in VATS sympathectomy for hyperhidrosis is as safe but less efficient when compared to a human camera-holding assistant. ES - 1569-9285 IL - 1569-9285 DI - icvts.2008.191353 DO - https://dx.doi.org/10.1510/icvts.2008.191353 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 19042929 [pubmed] ID - icvts.2008.191353 [pii] ID - 10.1510/icvts.2008.191353 [doi] PP - ppublish LG - English EP - 20081128 DP - 2009 Feb DC - 20090123 EZ - 2008/12/02 09:00 DA - 2009/04/21 09:00 DT - 2008/12/02 09:00 YR - 2009 ED - 20090420 RD - 20090123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19042929 <483. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18363061 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Wykypiel H AU - Bodner J AU - Wetscher G AU - Schmid T FA - Wykypiel, H FA - Bodner, J FA - Wetscher, G FA - Schmid, T TI - Robot-assisted versus conventional laparoscopic fundoplication: short-term outcome of a pilot randomized controlled study. CM - Comment on: Surg Endosc. 2007 Oct;21(10):1800-5; PMID: 17353978 SO - Surgical Endoscopy. 22(5):1407, 2008 May AS - Surg Endosc. 22(5):1407, 2008 May NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Education, Medical, Continuing MH - *Fundoplication/mt [Methods] MH - Humans MH - *Laparoscopy/mt [Methods] MH - Pilot Projects MH - Randomized Controlled Trials as Topic MH - Reoperation/ed [Education] MH - Reoperation/mt [Methods] MH - *Robotics MH - Treatment Outcome ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-008-9864-5 PT - Comment PT - Letter ID - 18363061 [pubmed] ID - 10.1007/s00464-008-9864-5 [doi] PP - ppublish PH - 2007/11/05 [received] PH - 2007/11/30 [accepted] LG - English EP - 20080325 DP - 2008 May DC - 20090112 EZ - 2008/03/26 09:00 DA - 2009/04/21 09:00 DT - 2008/03/26 09:00 YR - 2008 ED - 20090420 RD - 20090112 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18363061 <484. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19168868 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Vogelzang M AU - Vlaar PJ AU - Svilaas T AU - Amo D AU - Nijsten MW AU - Zijlstra F FA - Vogelzang, Mathijs FA - Vlaar, Pieter J FA - Svilaas, Tone FA - Amo, Diny FA - Nijsten, Maarten W N FA - Zijlstra, Felix IN - Vogelzang, Mathijs. Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. m.vogelzang@thorax.umcg.nl TI - Computer-assisted myocardial blush quantification after percutaneous coronary angioplasty for acute myocardial infarction: a substudy from the TAPAS trial. SO - European Heart Journal. 30(5):594-9, 2009 Mar AS - Eur Heart J. 30(5):594-9, 2009 Mar NJ - European heart journal PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - em8, 8006263 IO - Eur. Heart J. SB - Index Medicus CP - England MH - Aged MH - *Angioplasty, Balloon, Coronary/mt [Methods] MH - Coronary Angiography MH - Coronary Circulation MH - Epidemiologic Methods MH - Female MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/dg [Diagnostic Imaging] MH - Myocardial Infarction/pp [Physiopathology] MH - *Myocardial Infarction/th [Therapy] MH - Observer Variation MH - Prognosis MH - *Radiographic Image Interpretation, Computer-Assisted/mt [Methods] MH - Software Design MH - Treatment Outcome AB - AIMS: Myocardial reperfusion after acute myocardial infarction can be angiographically assessed by the myocardial blush grade (MBG) or TIMI Perfusion Grade. These scores are based on subjective human judgement and lead to a score of four categories. A more operator-independent way of scoring myocardial perfusion may facilitate research in this area. AB - METHODS AND RESULTS: We designed the 'Quantitative Blush Evaluator' (QuBE), a computer program which calculates a score for myocardial perfusion. This program will be freely available as open source software. The inter-observer concordance was 97.7%. We calculated values on prospectively collected angiograms in patients with acute ST-elevation myocardial infarction from the TAPAS trial. Quantitative blush evaluator values could be assessed on 790 out of 980 collected angiograms (81%). The QuBE score correlated significantly with MBG as determined by a core lab. The QuBE score predicted complete ST-elevation resolution, low enzyme levels, and 1 year survival (all P < 0.001). Quantitative blush evaluator value was an independent predictor of mortality at 1 year [OR 0.40 (0.17-0.90), P = 0.02]. AB - CONCLUSION: The QuBE program provides a practical, freely available computer-assisted assessment of myocardial perfusion. The QuBE score provides a useful surrogate endpoint in trials of therapies aimed at improving myocardial reperfusion. ES - 1522-9645 IL - 0195-668X DI - ehn542 DO - https://dx.doi.org/10.1093/eurheartj/ehn542 PT - Journal Article PT - Randomized Controlled Trial ID - 19168868 [pubmed] ID - ehn542 [pii] ID - 10.1093/eurheartj/ehn542 [doi] PP - ppublish LG - English EP - 20090124 DP - 2009 Mar DC - 20090302 EZ - 2009/01/27 09:00 DA - 2009/04/02 09:00 DT - 2009/01/27 09:00 YR - 2009 ED - 20090401 RD - 20161125 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19168868 <485. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19157434 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Rocco B AU - Rocco F FA - Rocco, Bernardo FA - Rocco, Francesco TI - Re: Assessment of early continence after reconstruction of the periprostatic tissues in patients undergoing computer assisted (robotic) prostatectomy: results of a 2 group parallel randomized controlled trial: M. Menon, F. Muhletaler, M. Campos and J. O. Peabody J Urol 2008; 180: 1018-1023. CM - Comment on: J Urol. 2008 Sep;180(3):1018-23; PMID: 18639300 SO - Journal of Urology. 181(3):1500-1; author reply 1501, 2009 Mar AS - J Urol. 181(3):1500-1; author reply 1501, 2009 Mar NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Humans MH - Male MH - *Prostatectomy/mt [Methods] MH - Randomized Controlled Trials as Topic MH - Recovery of Function MH - *Robotics MH - Urinary Incontinence/pc [Prevention & Control] MH - Urination ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(08)03087-5 DO - https://dx.doi.org/10.1016/j.juro.2008.11.047 PT - Comment PT - Letter ID - 19157434 [pubmed] ID - S0022-5347(08)03087-5 [pii] ID - 10.1016/j.juro.2008.11.047 [doi] PP - ppublish PH - 2008/10/16 [received] LG - English EP - 20090120 DP - 2009 Mar DC - 20090302 EZ - 2009/01/23 09:00 DA - 2009/03/28 09:00 DT - 2009/01/23 09:00 YR - 2009 ED - 20090327 RD - 20090302 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19157434 <486. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 19041972 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Judkins TN AU - Oleynikov D AU - Stergiou N FA - Judkins, Timothy N FA - Oleynikov, Dmitry FA - Stergiou, Nick IN - Judkins, Timothy N. Physical Therapy and Rehabilitation Science, University of Maryland School of Medicine, Baltimore, MD 21201, USA. tjudkins@gmail.com TI - Electromyographic response is altered during robotic surgical training with augmented feedback. SO - Journal of Biomechanics. 42(1):71-6, 2009 Jan 05 AS - J Biomech. 42(1):71-6, 2009 Jan 05 NJ - Journal of biomechanics PI - Journal available in: Print-Electronic PI - Citation processed from: Print JC - 0157375, hjf IO - J Biomech SB - Index Medicus CP - United States MH - Adult MH - Biofeedback, Psychology MH - Electromyography MH - *Feedback MH - Humans MH - *Physicians MH - *Robotics/ed [Education] MH - *Robotics/mt [Methods] MH - *Surgical Procedures, Operative/ed [Education] MH - *Surgical Procedures, Operative/mt [Methods] AB - There is a growing prevalence of robotic systems for surgical laparoscopy. We previously developed quantitative measures to assess robotic surgical proficiency, and used augmented feedback to enhance training to reduce applied grip force and increase speed. However, there is also a need to understand the physiological demands of the surgeon during robotic surgery, and if training can reduce these demands. Therefore, the goal of this study was to use clinical biomechanical techniques via electromyography (EMG) to investigate the effects of real-time augmented visual feedback during short-term training on muscular activation and fatigue. Twenty novices were trained in three inanimate surgical tasks with the da Vinci Surgical System. Subjects were divided into five feedback groups (speed, relative phase, grip force, video, and control). Time- and frequency-domain EMG measures were obtained before and after training. Surgical training decreased muscle work as found from mean EMG and EMG envelopes. Grip force feedback further reduced average and total muscle work, while speed feedback increased average muscle work and decreased total muscle work. Training also increased the median frequency response as a result of increased speed and/or reduced fatigue during each task. More diverse motor units were recruited as revealed by increases in the frequency bandwidth post-training. We demonstrated that clinical biomechanics using EMG analysis can help to better understand the effects of training for robotic surgery. Real-time augmented feedback during training can further reduce physiological demands. Future studies will investigate other means of feedback such as biofeedback of EMG during robotic surgery training. IS - 0021-9290 IL - 0021-9290 DI - S0021-9290(08)00502-2 DO - https://dx.doi.org/10.1016/j.jbiomech.2008.09.039 PT - Clinical Trial PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't ID - 19041972 [pubmed] ID - S0021-9290(08)00502-2 [pii] ID - 10.1016/j.jbiomech.2008.09.039 [doi] PP - ppublish PH - 2007/11/05 [received] PH - 2008/09/30 [revised] PH - 2008/09/30 [accepted] GI - No: K25HD047194 Organization: (HD) *NICHD NIH HHS* Country: United States LG - English EP - 20081129 DP - 2009 Jan 05 DC - 20090116 EZ - 2008/12/02 09:00 DA - 2009/03/07 09:00 DT - 2008/12/02 09:00 YR - 2009 ED - 20090306 RD - 20091119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=19041972 <487. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18813994 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Patriti A AU - Ceccarelli G AU - Bellochi R AU - Bartoli A AU - Spaziani A AU - Di Zitti L AU - Casciola L FA - Patriti, Alberto FA - Ceccarelli, Graziano FA - Bellochi, Raffaele FA - Bartoli, Alberto FA - Spaziani, Alessandro FA - Di Zitti, Lelio FA - Casciola, Luciano IN - Patriti, Alberto. Department of General, Vascular, Minimally Invasive and Robotic Surgery, San Matteo degli Infermi Hospital-Spoleto, Via Loreto, 3, 06049, Spoleto, Perugia, Italy. albertopatriti@gmail.com TI - Robot-assisted laparoscopic total and partial gastric resection with D2 lymph node dissection for adenocarcinoma. CM - Comment in: Surg Endosc. 2009 Aug;23(8):1919-21; author reply 1922-3; PMID: 19444513 SO - Surgical Endoscopy. 22(12):2753-60, 2008 Dec AS - Surg Endosc. 22(12):2753-60, 2008 Dec NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adenocarcinoma/dt [Drug Therapy] MH - Adenocarcinoma/pa [Pathology] MH - Adenocarcinoma/sc [Secondary] MH - *Adenocarcinoma/su [Surgery] MH - Aged MH - Aged, 80 and over MH - Chemotherapy, Adjuvant MH - Combined Modality Therapy MH - Feasibility Studies MH - Female MH - Follow-Up Studies MH - *Gastrectomy/mt [Methods] MH - Humans MH - *Laparoscopy/mt [Methods] MH - *Lymph Node Excision/mt [Methods] MH - Lymphatic Metastasis MH - Male MH - Middle Aged MH - Neoadjuvant Therapy MH - Prospective Studies MH - *Robotics/mt [Methods] MH - Stomach Neoplasms/dt [Drug Therapy] MH - Stomach Neoplasms/pa [Pathology] MH - *Stomach Neoplasms/su [Surgery] AB - BACKGROUND: Lymph node dissection and esophageal anastomosis, considered the more demanding steps of laparoscopic gastrectomy for gastric adenocarcinoma, can be performed with the use of a remote-controlled robot. AB - METHODS: Thirteen patients with a histologically proved gastric cancer (six stage I, six stage II, and one stage III) were enrolled in a prospective study to assess feasibility and safety of the Da Vinci surgical system in total and partial gastrectomy with extended lymph node dissection. Outcome measures were conversion rate, intra- and postoperative morbidity and mortality, operative time, blood loss, number of lymph nodes harvested, and macroscopic and microscopic evaluation of resection margins. AB - RESULTS: Eight distal, four total, and one proximal laparoscopic gastrectomies were completed without conversion. Extended lymph node dissection, and esophagojejunal and esophagogastric anastomoses were successfully carried out using the da Vinci System. Mean operative time was 286 +/- 32.6 min and blood loss was 103 +/- 87.5 ml. Mean number of nodes retrieved was 28.1 +/- 8.3 and all resection margins were negative. There was no mortality. Trocar bleeding requiring laparoscopy was the only major complication encountered. No recurrence occurred during a mean follow-up time of 12.2 +/- 4.5 months. AB - CONCLUSIONS: Robot-assisted laparoscopic lymph node dissection and esophageal anastomosis are feasible and safe. Longer follow-up time and randomized studies are needed to evaluate long-term outcome and clinical advantages of this new technology. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-008-0129-0 PT - Clinical Trial PT - Journal Article ID - 18813994 [pubmed] ID - 10.1007/s00464-008-0129-0 [doi] PP - ppublish PH - 2008/04/12 [received] PH - 2008/07/31 [accepted] PH - 2008/07/09 [revised] LG - English EP - 20080924 DP - 2008 Dec DC - 20081117 EZ - 2008/09/25 09:00 DA - 2009/02/20 09:00 DT - 2008/09/25 09:00 YR - 2008 ED - 20090219 RD - 20090716 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18813994 <488. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18803341 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Nguan C AU - Miller B AU - Patel R AU - Luke PP AU - Schlachta CM FA - Nguan, Christopher FA - Miller, Brian FA - Patel, Rajni FA - Luke, Patrick P W FA - Schlachta, Christopher M IN - Nguan, Christopher. Vancouver General Hospital, 6th floor, 2775 Laurel Street, Vancouver, British Columbia V5Z 1M9, Canada. chris@nguan.ca TI - Pre-clinical remote telesurgery trial of a da Vinci telesurgery prototype. SO - The International Journal Of Medical Robotics + Computer Assisted Surgery: MRCAS. 4(4):304-9, 2008 Dec AS - Int J Med Robot. 4(4):304-9, 2008 Dec NJ - The international journal of medical robotics + computer assisted surgery : MRCAS PI - Journal available in: Print PI - Citation processed from: Internet JC - 101250764 IO - Int J Med Robot SB - Index Medicus CP - England MH - Anastomosis, Surgical/is [Instrumentation] MH - Anastomosis, Surgical/mt [Methods] MH - Animals MH - Kidney Pelvis/su [Surgery] MH - Man-Machine Systems MH - Nova Scotia MH - Ontario MH - Robotics/mt [Methods] MH - Surgical Equipment MH - Swine MH - *Telemedicine/mt [Methods] MH - *Video-Assisted Surgery/mt [Methods] AB - BACKGROUND: The objective of this study was to perform a pre-clinical remote telesurgery trial of a da Vinci telesurgery prototype on a surgical-grade virtual private network. AB - METHODS: A da Vinci telesurgery-enabled prototype was used to conduct surgical trials across a 17 MB/s bandwidth VPNe network spanning 2848 km round-trip landline distance from London, Ontario, to Halifax, Nova Scotia, Canada. The outcomes measured during the trial were surgical times and quality of anastomoses. AB - RESULTS: Network configuration resulted in observed latencies of 370 ms with 140 ms due to transport delay. The da Vinci telesurgery prototype performed well subjectively and average porcine pyeloplasty anastomotic times were 20.7 +/- 4.7 min. AB - CONCLUSIONS: This work constitutes an early evaluation of the da Vinci telesurgery prototype for conceptually remote telesurgical operations. This study clearly demonstrated the feasibility of remote telesurgery using the da Vinci platform to perform a complex surgical task. ES - 1478-596X IL - 1478-5951 DO - https://dx.doi.org/10.1002/rcs.210 PT - Journal Article ID - 18803341 [pubmed] ID - 10.1002/rcs.210 [doi] PP - ppublish LG - English DP - 2008 Dec DC - 20081202 EZ - 2008/09/23 09:00 DA - 2009/02/07 09:00 DT - 2008/09/23 09:00 YR - 2008 ED - 20090206 RD - 20081202 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18803341 <489. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18722970 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Obermair A AU - Gebski V AU - Frumovitz M AU - Soliman PT AU - Schmeler KM AU - Levenback C AU - Ramirez PT FA - Obermair, Andreas FA - Gebski, Val FA - Frumovitz, Michael FA - Soliman, Pamela T FA - Schmeler, Kathleen M FA - Levenback, Charles FA - Ramirez, Pedro T IN - Obermair, Andreas. University of Queensland, School of Medicine, Department of Gynecological Oncology, Royal Brisbane and Women's Hospital, Herston, Brisbane, Queensland, Australia. Andreas_obermair@health.qld.gov.au TI - A phase III randomized clinical trial comparing laparoscopic or robotic radical hysterectomy with abdominal radical hysterectomy in patients with early stage cervical cancer. SO - Journal of Minimally Invasive Gynecology. 15(5):584-8, 2008 Sep-Oct AS - J Minim Invasive Gynecol. 15(5):584-8, 2008 Sep-Oct NJ - Journal of minimally invasive gynecology PI - Journal available in: Print PI - Citation processed from: Print JC - 101235322 IO - J Minim Invasive Gynecol SB - Index Medicus CP - United States MH - Adenocarcinoma/pa [Pathology] MH - *Adenocarcinoma/su [Surgery] MH - Adult MH - Carcinoma, Squamous Cell/pa [Pathology] MH - *Carcinoma, Squamous Cell/su [Surgery] MH - Cost-Benefit Analysis MH - Disease-Free Survival MH - Feasibility Studies MH - Female MH - Humans MH - *Hysterectomy/mt [Methods] MH - *Laparoscopy/mt [Methods] MH - Neoplasm Staging MH - *Robotics MH - Uterine Cervical Neoplasms/pa [Pathology] MH - *Uterine Cervical Neoplasms/su [Surgery] AB - STUDY OBJECTIVE: Cervical cancer is a significant health problem in countries of the developing world. Although case series suggest advantages of total laparoscopic radical hysterectomy (TLRH) compared with total abdominal radical hysterectomy (TARH), no randomized controlled trial is currently available to establish TLRH as the new standard treatment. In this study, TLRH or total robotic radical hysterectomy (TRRH) will be performed without a vaginally assisted portion of the procedure. AB - DESIGN: A biphasic randomized controlled trial was designed to test feasibility of recruitment and equivalence in regard to disease-free survival (Canadian Task Force classification I). AB - SETTING: Tertiary referral hospital. AB - PATIENTS: Patients with histologically confirmed invasive squamous cell carcinoma or adenocarcinoma of the cervix, stage IA1 (with lymphovascular space invasion), IA2, and IB1 are eligible. AB - INTERVENTIONS: During the first phase, 100 patients will be randomized (1:1) to receive either TLRH/TRRH or TARH, with the primary end point being the rate of enrollment. During the second phase, recruitment will be extended by another 640 patients in a 1:1 TLRH/TRRH:TARH allocation, to determine equivalence with respect to disease-free survival with 80% power and alpha=0.05. AB - MEASUREMENTS AND MAIN RESULTS: Equivalence will be assumed if the difference in disease-free survival does not exceed 7% at 4 years. Secondary outcomes include treatment-related morbidity, costs and cost effectiveness, patterns of recurrence, quality of life, pelvic floor function, feasibility of intraoperative sentinel node sampling, and overall survival. All data from this multicenter study will be entered using online electronic case report forms, allowing real-time assessment of data completeness and patient follow-up. AB - CONCLUSION: This prospective trial aims to show the equivalence of a TLRH/TRRH versus TARH approach for patients with early stage cervical cancer following a 2-phase protocol. This trial was developed and designed with the input and approval of the members of the Gynecologic Oncology Committee from the American Association of Gynecologic Laparoscopists. IS - 1553-4650 IL - 1553-4650 DI - S1553-4650(08)00293-8 DO - https://dx.doi.org/10.1016/j.jmig.2008.06.013 PT - Clinical Trial, Phase III PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial ID - 18722970 [pubmed] ID - S1553-4650(08)00293-8 [pii] ID - 10.1016/j.jmig.2008.06.013 [doi] PP - ppublish PH - 2008/04/04 [received] PH - 2008/06/19 [revised] PH - 2008/06/21 [accepted] LG - English DP - 2008 Sep-Oct DC - 20080825 EZ - 2008/08/30 09:00 DA - 2009/01/28 09:00 DT - 2008/08/30 09:00 YR - 2008 ED - 20090127 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18722970 <490. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18972334 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hohlweg-Majert B AU - Metzger MC AU - Bohm J AU - Muecke T AU - Schulze D FA - Hohlweg-Majert, Bettina FA - Metzger, Marc C FA - Bohm, Joachim FA - Muecke, Thomas FA - Schulze, Dirk IN - Hohlweg-Majert, Bettina. Department of Oral and Maxillofacial Surgery, Technical University Munich, Munich, Germany. majert@mkg.med.tum.de TI - Advanced imaging findings and computer-assisted surgery of suspected synovial chondromatosis in the temporomandibular joint. SO - Journal of Magnetic Resonance Imaging. 28(5):1251-7, 2008 Nov AS - J Magn Reson Imaging. 28(5):1251-7, 2008 Nov NJ - Journal of magnetic resonance imaging : JMRI PI - Journal available in: Print PI - Citation processed from: Print JC - beo, 9105850 IO - J Magn Reson Imaging SB - Index Medicus CP - United States MH - Adolescent MH - Adult MH - Child MH - *Chondromatosis, Synovial/di [Diagnosis] MH - *Chondromatosis, Synovial/su [Surgery] MH - Female MH - Humans MH - *Image Enhancement/mt [Methods] MH - *Image Interpretation, Computer-Assisted/mt [Methods] MH - Male MH - Middle Aged MH - *Surgery, Computer-Assisted/mt [Methods] MH - *Temporomandibular Joint Disorders/di [Diagnosis] MH - *Temporomandibular Joint Disorders/su [Surgery] MH - Treatment Outcome MH - Young Adult AB - Synovial chondromatosis of the joint occurs mainly in teenagers and young adults. Only 3% of these neoplasms are located in the head and neck region. Synovial chondromatosis of the temporomandibular joint is therefore a very rare disorder. Therefore, developing a working, histological confirmation is required for differential diagnosis. In this case series, the outcome of histological investigation and imaging techniques are compared. Based on clinical symptoms, five cases of suspected synovial chondromatosis of the temporomandibular joint are presented. In each of the subjects, the diagnosis was confirmed by histology. Specific imaging features for each case are described. The tomography images were compared with the histological findings. All patients demonstrated preauricular swelling, dental midline deviation, and limited mouth opening. Computer-assisted surgery was performed. Histology disclosed synovial chondromatosis of the temporomandibular joint in four cases. The other case was found to be a developmental disorder of the tympanic bone. The diagnosis of synovial chondromatosis of the temporomandibular joint can only be based on histology. Clinical symptoms are too general and the available imaging techniques only show nonspecific tumorous destruction, infiltration, and/or residual calcified bodies, they are only for advanced cases. A rare developmental disorder of the tympanic bone--persistence of foramen of Huschke--has to be differentiated. AB - Copyright (c) 2008 Wiley-Liss, Inc. IS - 1053-1807 IL - 1053-1807 DO - https://dx.doi.org/10.1002/jmri.21581 PT - Clinical Trial PT - Journal Article ID - 18972334 [pubmed] ID - 10.1002/jmri.21581 [doi] PP - ppublish LG - English DP - 2008 Nov DC - 20081103 EZ - 2008/10/31 09:00 DA - 2009/01/23 09:00 DT - 2008/10/31 09:00 YR - 2008 ED - 20090122 RD - 20081103 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18972334 <491. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18603748 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Mehta Y AU - Arora D AU - Sharma KK AU - Mishra Y AU - Wasir H AU - Trehan N FA - Mehta, Yatin FA - Arora, Dheeraj FA - Sharma, Krishna K FA - Mishra, Yugal FA - Wasir, Harpreet FA - Trehan, Naresh IN - Mehta, Yatin. Department of Anaesthesiology and Critical Care, Escorts Heart Institute and Research Centre, New Delhi, India. yatinmehta@hotmail.com TI - Comparison of continuous thoracic epidural and paravertebral block for postoperative analgesia after robotic-assisted coronary artery bypass surgery. SO - Annals of Cardiac Anaesthesia. 11(2):91-6, 2008 Jul-Dec AS - Ann. Card. Anaesth.. 11(2):91-6, 2008 Jul-Dec NJ - Annals of cardiac anaesthesia PI - Journal available in: Print PI - Citation processed from: Print JC - 9815987 IO - Ann Card Anaesth SB - Index Medicus CP - India MH - Analgesia, Epidural/ae [Adverse Effects] MH - *Analgesia, Epidural/mt [Methods] MH - *Coronary Artery Bypass/mt [Methods] MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Minimally Invasive Surgical Procedures/mt [Methods] MH - Nerve Block/ae [Adverse Effects] MH - *Nerve Block/mt [Methods] MH - Pain Measurement MH - Postoperative Complications MH - Prospective Studies MH - Respiratory Function Tests MH - *Robotics MH - Treatment Outcome AB - Minimally invasive surgery with robotic assistance should elicit minimal pain. Regional analgesic techniques have shown excellent analgesia after thoracotomy. Thus the aim of this study was to compare thoracic epidural analgesia (TEA) technique with paravertebral block (PVB) technique in these patients with regard to quality of analgesia, complications, and haemodynamic and respiratory parameters. This was a prospective randomised study involving 36 patients undergoing elective robotic-assisted coronary artery bypass grafting (CABG). TEA or PVB were administered in these patients. The results revealed no significant differences with regard to demographics, haemodynamics, and arterial blood gases. Pulmonary functions were better maintained in PVB group postoperatively; however, this was statistically insignificant. The quality of analgesia was also comparable in both the groups. We conclude that PVB is a safe and effective technique for postoperative analgesia after robotic-assisted CABG and is comparable to TEA with regard to quality of analgesia. IS - 0971-9784 IL - 0971-9784 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 18603748 [pubmed] PP - ppublish LG - English DP - 2008 Jul-Dec DC - 20080707 EZ - 2008/07/08 09:00 DA - 2009/01/15 09:00 DT - 2008/07/08 09:00 YR - 2008 ED - 20090114 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18603748 <492. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18765042 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kanumuri P AU - Ganai S AU - Wohaibi EM AU - Bush RW AU - Grow DR AU - Seymour NE FA - Kanumuri, Prathima FA - Ganai, Sabha FA - Wohaibi, Eyad M FA - Bush, Ronald W FA - Grow, Daniel R FA - Seymour, Neal E IN - Kanumuri, Prathima. Baystate Medical Center, Department of Surgery, Tufts University School of Medicine, Springfield, Massachusetts 01199, USA. TI - Virtual reality and computer-enhanced training devices equally improve laparoscopic surgical skill in novices. SO - Journal of the Society of Laparoendoscopic Surgeons. 12(3):219-26, 2008 Jul-Sep AS - J Soc Laparoendosc Surg. 12(3):219-26, 2008 Jul-Sep NJ - JSLS : Journal of the Society of Laparoendoscopic Surgeons PI - Journal available in: Print PI - Citation processed from: Print JC - 100884618, c8o IO - JSLS PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3015873 SB - Index Medicus CP - United States MH - Adult MH - *Clinical Competence MH - *Computer-Assisted Instruction MH - *Education, Medical, Undergraduate/mt [Methods] MH - Educational Measurement MH - Female MH - *General Surgery/ed [Education] MH - Humans MH - *Laparoscopy MH - Male MH - Statistics, Nonparametric MH - Suture Techniques MH - *User-Computer Interface AB - BACKGROUND: The study aim was to compare the effectiveness of virtual reality and computer-enhanced videoscopic training devices for training novice surgeons in complex laparoscopic skills. AB - METHODS: Third-year medical students received instruction on laparoscopic intracorporeal suturing and knot tying and then underwent a pretraining assessment of the task using a live porcine model. Students were then randomized to objectives-based training on either the virtual reality (n=8) or computer-enhanced (n=8) training devices for 4 weeks, after which the assessment was repeated. AB - RESULTS: Posttraining performance had improved compared with pretraining performance in both task completion rate (94% versus 18%; P<0.001*) and time [181+/-58 (SD) versus 292+/-24*]. Performance of the 2 groups was comparable before and after training. Of the subjects, 88% thought that haptic cues were important in simulators. Both groups agreed that their respective training systems were effective teaching tools, but computer-enhanced device trainees were more likely to rate their training as representative of reality (P<0.01). AB - CONCLUSIONS: Training on virtual reality and computer-enhanced devices had equivalent effects on skills improvement in novices. Despite the perception that haptic feedback is important in laparoscopic simulation training, its absence in the virtual reality device did not impede acquisition of skill. IS - 1086-8089 IL - 1086-8089 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 18765042 [pubmed] ID - PMC3015873 [pmc] PP - ppublish LG - English DP - 2008 Jul-Sep DC - 20080903 EZ - 2008/09/04 09:00 DA - 2009/01/09 09:00 DT - 2008/09/04 09:00 YR - 2008 ED - 20090108 RD - 20161020 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18765042 <493. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18613274 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Akl MN AU - Magrina JF AU - Kho RM AU - Magtibay PM FA - Akl, Mohamed N FA - Magrina, Javier F FA - Kho, Rosanne M FA - Magtibay, Paul M IN - Akl, Mohamed N. Department of Gynecologic Surgery, Mayo Clinic Arizona, 5777 East Mayo Boulevard, Phoenix, AZ 85054, USA. Akl.Mohamed@mayo.edu TI - Robotic appendectomy in gynaecological surgery: technique and pathological findings. SO - The International Journal Of Medical Robotics + Computer Assisted Surgery: MRCAS. 4(3):210-3, 2008 Sep AS - Int J Med Robot. 4(3):210-3, 2008 Sep NJ - The international journal of medical robotics + computer assisted surgery : MRCAS PI - Journal available in: Print PI - Citation processed from: Internet JC - 101250764 IO - Int J Med Robot SB - Index Medicus CP - England MH - Adult MH - *Appendectomy/mt [Methods] MH - *Appendicitis/pa [Pathology] MH - *Appendicitis/su [Surgery] MH - Female MH - *Gynecologic Surgical Procedures/mt [Methods] MH - Humans MH - *Laparoscopy/mt [Methods] MH - Middle Aged MH - *Robotics/mt [Methods] MH - *Surgery, Computer-Assisted/mt [Methods] MH - Treatment Outcome AB - BACKGROUND: We evaluated the feasibility, safety and pathological findings of incidental robotic appendectomy in patients undergoing robotic gynaecological surgery. AB - METHODS: Retrospective analysis of 107 consecutive cases of robotic appendectomy done in conjunction with other robotic gynaecological procedures between May 2004 and January 2007. AB - RESULTS: All appendectomies were performed robotically in conjunction with other robotic procedures. Mean time for appendectomy was 3.4 min. No perioperative complications related to appendectomy were encountered. Among 90 patients with no gynaecological malignancy, 57 patients reported chronic pelvic pain preoperatively and 21 (37%) of them had an abnormal appendiceal pathology as compared to only 5 (15%) of the 33 patients with no pelvic pain (OR. 3.2; 95% CI, 1.1-9.7, p = 0.032). Of seven patients with ovarian malignancy, three (42%) had appendicular metastasis. AB - CONCLUSION: Incidental robotic appendectomy can be performed safely without the need for switching to conventional laparoscopy. It should be considered in patients undergoing robotic pelvic surgery for pelvic pain and ovarian malignancy. ES - 1478-596X IL - 1478-5951 DO - https://dx.doi.org/10.1002/rcs.198 PT - Controlled Clinical Trial PT - Journal Article ID - 18613274 [pubmed] ID - 10.1002/rcs.198 [doi] PP - ppublish LG - English DP - 2008 Sep DC - 20080911 EZ - 2008/07/10 09:00 DA - 2008/12/17 09:00 DT - 2008/07/10 09:00 YR - 2008 ED - 20081124 RD - 20080911 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18613274 <494. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18566965 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Wurm J AU - Bohr C AU - Iro H AU - Bumm K FA - Wurm, Jochen FA - Bohr, Christopher FA - Iro, Heinrich FA - Bumm, Klaus IN - Wurm, Jochen. Department of Otorhinolaryngology, Head and Neck Surgery, University Erlangen, Germany. jochen.wurm@uk-erlangen.de TI - Intra-operative image update: first experiences with new software in computer-assisted sinus surgery. SO - The International Journal Of Medical Robotics + Computer Assisted Surgery: MRCAS. 4(3):202-9, 2008 Sep AS - Int J Med Robot. 4(3):202-9, 2008 Sep NJ - The international journal of medical robotics + computer assisted surgery : MRCAS PI - Journal available in: Print PI - Citation processed from: Internet JC - 101250764 IO - Int J Med Robot SB - Index Medicus CP - England MH - Adult MH - Aged MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Paranasal Sinuses/dg [Diagnostic Imaging] MH - *Paranasal Sinuses/su [Surgery] MH - Pilot Projects MH - *Radiographic Image Interpretation, Computer-Assisted/mt [Methods] MH - *Robotics/mt [Methods] MH - *Software MH - Software Design MH - *Surgery, Computer-Assisted/mt [Methods] MH - Tomography, X-Ray Computed/mt [Methods] MH - *User-Computer Interface AB - BACKGROUND: So far, conventional navigation systems do not provide the opportunity for any modification of acquired image datasets. In particular, the surgical progress in the operating field cannot be visualized unless new imaging scans are performed. AB - METHODS: In a feasibility study, new software creating intra-operative image updates by virtual means was tested in conjunction with conventional navigation. With this new software, surgically removed tissue volumes can be traced and viewed directly within the diagnostic image data. AB - RESULTS AND CONCLUSIONS: The new software represents an interesting and helpful amendment to conventional computer-assisted surgery in selected cases. During surgical procedures around bony structures, the surgeon gets an accurate virtual image update of the surgical progress in the operating field and the amount of tissue removed. However, in cases where mobile structures are present or soft tissue shifts are expected, this feature seems to be suitable only to a limited extent. ES - 1478-596X IL - 1478-5951 DO - https://dx.doi.org/10.1002/rcs.197 PT - Clinical Trial PT - Journal Article ID - 18566965 [pubmed] ID - 10.1002/rcs.197 [doi] PP - ppublish LG - English DP - 2008 Sep DC - 20080911 EZ - 2008/06/21 09:00 DA - 2008/12/17 09:00 DT - 2008/06/21 09:00 YR - 2008 ED - 20081124 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18566965 <495. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18054354 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Dharia Patel SP AU - Steinkampf MP AU - Whitten SJ AU - Malizia BA FA - Dharia Patel, Sejal P FA - Steinkampf, Michael P FA - Whitten, Scott J FA - Malizia, Beth A IN - Dharia Patel, Sejal P. Department of Obstetrics and Gynecology, the Ohio State University, Columbus, Ohio 43210, USA. dhariavxr@hotmail.com TI - Robotic tubal anastomosis: surgical technique and cost effectiveness. SO - Fertility & Sterility. 90(4):1175-9, 2008 Oct AS - Fertil Steril. 90(4):1175-9, 2008 Oct NJ - Fertility and sterility PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - evf, 0372772 IO - Fertil. Steril. SB - Index Medicus CP - United States MH - Adult MH - *Anastomosis, Surgical/ec [Economics] MH - Anastomosis, Surgical/mt [Methods] MH - Anastomosis, Surgical/sn [Statistics & Numerical Data] MH - Cost-Benefit Analysis MH - *Fallopian Tubes/su [Surgery] MH - Feasibility Studies MH - Female MH - *Health Care Costs/sn [Statistics & Numerical Data] MH - Humans MH - *Infertility, Female/ec [Economics] MH - *Infertility, Female/su [Surgery] MH - Laparotomy/ec [Economics] MH - Laparotomy/sn [Statistics & Numerical Data] MH - Pregnancy MH - Pregnancy Outcome/ec [Economics] MH - *Robotics/ec [Economics] MH - Robotics/sn [Statistics & Numerical Data] MH - *Surgery, Computer-Assisted/ec [Economics] MH - Surgery, Computer-Assisted/sn [Statistics & Numerical Data] MH - Treatment Outcome MH - United States AB - OBJECTIVE: To evaluate the feasibility of robotic microsurgical tubal anastomosis and compare the results and cost effectiveness with the same procedure performed by laparotomy. AB - DESIGN: Prospective cohort study. AB - SETTING: University hospital. AB - PATIENT(S): Patients with a history of bilateral tubal ligation who desired reversal for future fertility. AB - INTERVENTION(S): Tubal anastomoses through either a robotic approach or through a laparotomy. AB - MAIN OUTCOME MEASURE(S): Operative times, hospitalization, complications, postoperative patency, clinical outcomes, and the cost per live birth. AB - RESULT(S): The mean operative time for robotic anastomoses was statistically significantly greater than open anastomoses (ROBOT 201 minutes; OPEN 155.3 minutes), although hospitalization times were statistically significantly shorter (ROBOT 4 hours; OPEN 34.7 hours). The return to instrumental activities of daily living was accelerated in the patients who had undergone a robotic anastomosis (ROBOT 11.1 days; OPEN 28.1 days). Although this was a small series, the pregnancy rates were comparable between groups (ROBOT 62.5%; OPEN 50%), yet the rate of abnormal pregnancy was higher in the robotic group (ectopic: ROBOT 4, OPEN 1; spontaneous pregnancy loss: ROBOT 2, OPEN 1). The cost per delivery was similar between the groups (ROBOT $92,488.00, OPEN $92,205.90). AB - CONCLUSION(S): Robotically assisted laparoscopic microsurgical tubal anastomosis is feasible and cost effective with results that are comparable with the traditional open approach. ES - 1556-5653 IL - 0015-0282 DI - S0015-0282(07)03145-7 DO - https://dx.doi.org/10.1016/j.fertnstert.2007.07.1392 PT - Controlled Clinical Trial PT - Journal Article ID - 18054354 [pubmed] ID - S0015-0282(07)03145-7 [pii] ID - 10.1016/j.fertnstert.2007.07.1392 [doi] PP - ppublish PH - 2007/03/12 [received] PH - 2007/07/05 [revised] PH - 2007/07/05 [accepted] LG - English EP - 20071203 DP - 2008 Oct DC - 20081020 EZ - 2007/12/07 09:00 DA - 2008/11/15 09:00 DT - 2007/12/07 09:00 YR - 2008 ED - 20081114 RD - 20081020 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18054354 <496. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18503924 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Saager L AU - Collins GL AU - Burnside B AU - Tymkew H AU - Zhang L AU - Jacobsohn E AU - Avidan M FA - Saager, Leif FA - Collins, Gordon L FA - Burnside, Beth FA - Tymkew, Heidi FA - Zhang, Lini FA - Jacobsohn, Eric FA - Avidan, Michael IN - Saager, Leif. Department of Anesthesiology, Washington University School of Medicine, St Louis, MO 63110, USA. TI - A randomized study in diabetic patients undergoing cardiac surgery comparing computer-guided glucose management with a standard sliding scale protocol. SO - Journal of Cardiothoracic & Vascular Anesthesia. 22(3):377-82, 2008 Jun AS - J Cardiothorac Vasc Anesth. 22(3):377-82, 2008 Jun NJ - Journal of cardiothoracic and vascular anesthesia PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - a6i, 9110208 IO - J. Cardiothorac. Vasc. Anesth. SB - Index Medicus CP - United States MH - Aged MH - Aged, 80 and over MH - Blood Glucose/an [Analysis] MH - *Blood Glucose/me [Metabolism] MH - *Cardiovascular Surgical Procedures/mt [Methods] MH - Cardiovascular Surgical Procedures/st [Standards] MH - *Diabetes Mellitus/bl [Blood] MH - Diabetes Mellitus/dt [Drug Therapy] MH - *Diabetes Mellitus/su [Surgery] MH - Disease Management MH - *Drug Therapy, Computer-Assisted/mt [Methods] MH - *Drug Therapy, Computer-Assisted/st [Standards] MH - Female MH - Glucose/ad [Administration & Dosage] MH - Humans MH - Male MH - Middle Aged MH - Monitoring, Intraoperative/mt [Methods] MH - Monitoring, Intraoperative/st [Standards] MH - Prospective Studies AB - OBJECTIVE: The aim of this study was to compare a standard insulin protocol with a computer-guided glucose management system to determine which method achieves tighter glucose control. AB - DESIGN: A prospective, randomized trial. AB - SETTING: A cardiothoracic intensive care unit (ICU) in a large academic medical center. AB - PARTICIPANTS: Forty patients with diabetes mellitus who were scheduled for cardiac surgery. AB - INTERVENTIONS: After induction of anesthesia and for the first 9 hours in the ICU, each subject received a standardized infusion of a 10% glucose solution at a rate of 1.0 mL/kg/h (ideal body weight). The subjects were then randomized to have their glucose controlled by either a paper-based insulin protocol or by a computer-guided glucose management system (CG). The desired range for blood glucose was set between 90 and 150 mg/dL. AB - MEASUREMENTS AND MAIN RESULTS: There were no differences between groups in baseline characteristics. Patients in the CG group spent more time in the desired range during both the intraoperative phase (49% v 27%, p = 0.001) and the ICU phase (84% v 60%, p < 0.0001). There were no statistical differences between groups in the number of hypoglycemia episodes. AB - CONCLUSIONS: The computer-guided glucose management system achieved tighter blood glucose control than a standard paper-based protocol in diabetic patients undergoing cardiac surgery. However, the low proportion of blood glucose recordings within the desired range in both groups during the intraoperative period reflects the challenges associated with achieving normoglycemia during cardiac surgery. RN - 0 (Blood Glucose) RN - IY9XDZ35W2 (Glucose) ES - 1532-8422 IL - 1053-0770 DI - S1053-0770(07)00289-3 DO - https://dx.doi.org/10.1053/j.jvca.2007.09.013 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 18503924 [pubmed] ID - S1053-0770(07)00289-3 [pii] ID - 10.1053/j.jvca.2007.09.013 [doi] PP - ppublish PH - 2007/05/01 [received] LG - English EP - 20071203 DP - 2008 Jun DC - 20080527 EZ - 2008/05/28 09:00 DA - 2008/10/31 09:00 DT - 2008/05/28 09:00 YR - 2008 ED - 20081030 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18503924 <497. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18575012 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tschopp KP AU - Thomaser EG FA - Tschopp, Kurt P FA - Thomaser, Esther G IN - Tschopp, Kurt P. Department of Otolaryngology, Head and Neck Surgery, Cantonal Hospital of Liestal, Liestal, Switzerland. kurt.tschopp@ksli.ch TI - Outcome of functional endonasal sinus surgery with and without CT-navigation. CM - Comment in: Rhinology. 2008 Jun;46(2):81; PMID: 18575005 SO - Rhinology. 46(2):116-20, 2008 Jun AS - Rhinology. 46(2):116-20, 2008 Jun NJ - Rhinology PI - Journal available in: Print PI - Citation processed from: Print JC - 0347242, tex IO - Rhinology SB - Index Medicus CP - Netherlands MH - Adult MH - Aged MH - *Endoscopy MH - Ethmoid Sinus MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - *Paranasal Sinus Diseases/dg [Diagnostic Imaging] MH - Paranasal Sinus Diseases/pa [Pathology] MH - *Paranasal Sinus Diseases/su [Surgery] MH - Prospective Studies MH - Quality of Life MH - Sphenoid Sinus MH - *Surgery, Computer-Assisted MH - *Tomography, X-Ray Computed MH - Treatment Outcome AB - INTRODUCTION: Computer-assisted surgery (CAS) has found widespread use in functional endonasal sinus surgery (FESS) over the past few years. The present study investigates if CAS leads to a better outcome in FESS. AB - MATERIAL AND METHODS: All patients who underwent endonasal sphenoethmoidectomy were enrolled in a prospective, non-randomized case-control study. The procedures were done without CAS (group A) in 2003 and with CAS (group B) in 2004, using a Stryker navigation unit. Sixty-two patients (113 sphenoidectomies) were included in group A and 61 patients (109 sphenoidectomies) in group B. The underlying disease was recurrent chronic sinusitis or polyposis nasi in all patients except for inverted papilloma in one patient from group A and in two patients from group B. The follow-up period was 12 months. Symptom scores were assessed preoperatively and at 12 months postoperatively, using a questionnaire. A CT-scan was obtained in all patients preoperatively and at 6 months postoperatively. AB - RESULTS: No significant difference was found between group A and B, neither with respect to symptom scores at 12 months postoperatively, nor in postoperative CT-scans. The operation strategy did not change by the introduction of CAS. The frontal sinuses were entered in group A and B in 59% and 64% of the patients, respectively. All parameters improved significantly postoperatively, compared to the preoperative values. As far as complications are concerned, two anterior orbital injuries and one retrobulbar haematoma occurred in group A and one postoperative lacrimal stenosis in group B. AB - CONCLUSIONS: CAS does not lead to a better clinical outcome in FESS. Our data suggest that the rate of complications may be reduced using CAS. However, studies with a much larger number of patients would be necessary in order to definitely answer the question of whether CAS reduce complications in FESS. IS - 0300-0729 IL - 0300-0729 PT - Controlled Clinical Trial PT - Journal Article ID - 18575012 [pubmed] PP - ppublish LG - English DP - 2008 Jun DC - 20080625 EZ - 2008/06/26 09:00 DA - 2008/10/23 09:00 DT - 2008/06/26 09:00 YR - 2008 ED - 20081022 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18575012 <498. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18484875 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Zorn KC AU - Gofrit ON AU - Steinberg GP AU - Taxy JB AU - Zagaja GP AU - Shalhav AL FA - Zorn, Kevin C FA - Gofrit, Ofer N FA - Steinberg, Gary P FA - Taxy, Jerome B FA - Zagaja, Gregory P FA - Shalhav, Arieh L IN - Zorn, Kevin C. Section of Urology, University of Chicago, Pritzker School of Medicine, Chicago, Illinois 60637, USA. kevinzorn@hotmail.com TI - Planned nerve preservation to reduce positive surgical margins during robot-assisted laparoscopic radical prostatectomy. SO - Journal of Endourology. 22(6):1303-9, 2008 Jun AS - J Endourol. 22(6):1303-9, 2008 Jun NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - *Prostate/ir [Innervation] MH - *Prostate/su [Surgery] MH - *Prostatectomy/mt [Methods] MH - *Robotics/mt [Methods] AB - PURPOSE: The main objective of radical prostatectomy (RP) is optimal oncologic resection with preservation of sexual function (SF). During our initial experience with robot-assisted laparoscopic radical prostatectomy (RLRP), we noted a high rate of posterolateral location of positive surgical margins (PSM) with nerve preservation (NP). With its magnified view of the surgical field and improved instrument precision, one potential advantage of RLRP is the ability to tailor the degree of NP. We evaluated the effect of a protocol for side-specific NP based on preoperative variables on PSM rates and SF outcomes. AB - METHODS: Between June and November 2006, 150 consecutive RLRPs were performed using a surgical protocol to select side-specific NP techniques (interfascial [IF], partial extrafascial [pEF], and wide extrafascial resection [WEFR]) based on preoperative risk factors (clinical stage, biopsy Gleason score, percentage of positive cores and maximal core cancer percentage, and preoperative PSA). Pathologic and SF outcomes in these patients were compared with those of a control group of 245 consecutive RLRPs in whom non-selective IF dissection was performed. All data were prospectively collected. AB - RESULTS: Mean patient age, PSA, clinical stage, biopsy Gleason score and positive core involvement, pathologic Gleason score, and stage were comparable among the two groups. The overall PSM rate (12.6% nu 20.4%; P = 0.04) and posterolateral location of PSMs (37% nu 70%; P = 0.04) were significantly lower in the study group. At 12 months, potency was reported in 80%, 67%, and 11% of men undergoing bilateral IFNP, partial extrafascial nerve preservation (pEFNP), and WEFR, respectively (P = 0.27). AB - CONCLUSIONS: Planning side-specific NP during RLRP, according to selected preoperative variables, can significantly reduce overall and posterolateral PSM rates. Furthermore, partial nerve sparing (pEFNP) also appears to confer favorable early SF outcomes. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2008.0009 PT - Clinical Trial PT - Journal Article ID - 18484875 [pubmed] ID - 10.1089/end.2008.0009 [doi] PP - ppublish LG - English DP - 2008 Jun DC - 20080626 EZ - 2008/05/20 09:00 DA - 2008/10/07 09:00 DT - 2008/05/20 09:00 YR - 2008 ED - 20081006 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18484875 <499. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18455762 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Yee DS AU - Ornstein DK FA - Yee, David S FA - Ornstein, David K IN - Yee, David S. Department of Urology, University of California, Irvine, School of Medicine, Orange, California 92868, USA. dyee@uci.edu TI - Repair of rectal injury during robotic-assisted laparoscopic prostatectomy. SO - Urology. 72(2):428-31, 2008 Aug AS - Urology. 72(2):428-31, 2008 Aug NJ - Urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Aged MH - Humans MH - Incidence MH - *Laparoscopy/ae [Adverse Effects] MH - Laparoscopy/mt [Methods] MH - Male MH - *Prostatectomy/ae [Adverse Effects] MH - Prostatectomy/mt [Methods] MH - Rectal Diseases/ep [Epidemiology] MH - Rectal Diseases/su [Surgery] MH - *Rectum/in [Injuries] MH - *Rectum/su [Surgery] MH - *Robotics MH - Surgical Flaps MH - Suture Techniques MH - Treatment Outcome AB - INTRODUCTION: Rectal injury is a potential devastating complication in radical prostatectomy. We reviewed the incidence and management of rectal injuries with robotic-assisted laparoscopic radical prostatectomy performed by a single surgeon. Of the first 251 robotic-assisted laparoscopic radical prostatectomies performed, 2 (0.8%) were complicated by rectal injury. AB - TECHNICAL CONSIDERATIONS: All patients underwent bowel preparation and received preoperative intravenous antibiotics. Both rectal injuries were detected intraoperatively and treated robotically. The rectotomy was closed in two layers of absorbable sutures and imbricated with a nonabsorbable suture. The rectum was then tacked to the levator fibers on one side with nonabsorbable suture to pull the injury away from the vesicourethral anastomosis. An omental flap was developed and tacked posterior to the urethra to cover the repair. A closed suction drain was placed. After surgery, the patients received broad-spectrum intravenous antibiotics and resumed oral intake on postoperative day 1. At 2 weeks, the Foley catheter was removed after voiding cystourethrography confirmed no extravasation. AB - CONCLUSIONS: Rectal injury during robotic-assisted laparoscopic radical prostatectomy can be identified and managed intraoperatively without requiring open conversion. A three-layer closure tacked away from the vesicourethral anastomosis and reinforced by an omental flap resulted in an uneventful recovery. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(07)02591-5 DO - https://dx.doi.org/10.1016/j.urology.2007.12.022 PT - Clinical Trial PT - Journal Article ID - 18455762 [pubmed] ID - S0090-4295(07)02591-5 [pii] ID - 10.1016/j.urology.2007.12.022 [doi] PP - ppublish PH - 2007/08/08 [received] PH - 2007/11/07 [revised] PH - 2007/12/04 [accepted] LG - English EP - 20080502 DP - 2008 Aug DC - 20080805 EZ - 2008/05/06 09:00 DA - 2008/10/01 09:00 DT - 2008/05/06 09:00 YR - 2008 ED - 20080930 RD - 20080805 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18455762 <500. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18639300 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Menon M AU - Muhletaler F AU - Campos M AU - Peabody JO FA - Menon, Mani FA - Muhletaler, Fred FA - Campos, Miguel FA - Peabody, James O IN - Menon, Mani. Vattikuti Urology Institute, Henry Ford Hospital, Detroit, Michigan 48202, USA. TI - Assessment of early continence after reconstruction of the periprostatic tissues in patients undergoing computer assisted (robotic) prostatectomy: results of a 2 group parallel randomized controlled trial. CM - Comment in: J Urol. 2009 Mar;181(3):1500-1; author reply 1501; PMID: 19157434 SO - Journal of Urology. 180(3):1018-23, 2008 Sep AS - J Urol. 180(3):1018-23, 2008 Sep NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Anastomosis, Surgical MH - Humans MH - Male MH - Middle Aged MH - Postoperative Complications/pc [Prevention & Control] MH - *Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/su [Surgery] MH - *Reconstructive Surgical Procedures/mt [Methods] MH - *Robotics MH - Treatment Outcome MH - Urethra/su [Surgery] MH - *Urinary Incontinence/et [Etiology] MH - *Urinary Incontinence/pc [Prevention & Control] AB - PURPOSE: Several case series have shown that reconstruction of the anterior or posterior periprostatic tissues facilitates early return of urinary continence after radical prostatectomy. We conducted a randomized clinical trial comparing early continence rates in patients undergoing urethrovesical anastomosis with or without periprostatic reconstruction. AB - MATERIALS AND METHODS: A total of 116 consecutive patients undergoing computer assisted (robotic) prostatectomy performed by 1 of 2 experienced surgeons were randomized to single (without periprostatic reconstruction) or double layer (with periprostatic tissue reconstruction) urethrovesical anastomosis. Urinary loss was measured by pad weight at 1, 2, 7 and 30 days after catheter removal. Patients and data gatherers were blinded to treatment allocation. AB - RESULTS: There were 57 patients randomized to the single and 59 to the double layer anastomosis group. All patients completed the study and followup. Using the conventional definition of urinary continence (0 to 1 pads daily) 26% and 34%, 49% and 46%, 51% and 54%, and 74% and 80% of patients undergoing single layer or double layer anastomoses were continent at 1, 2, 7 and 30 days, respectively (p >0.1). Of the patients in the 2 groups 7% and 15%, 14% and 14%, 16% and 20%, and 47% and 42% had no urinary leakage (0 gm or 0 pads daily) at these intervals, respectively (p >0.1). In each group 1 patient required prolonged catheterization because of cystographic evidence of anastomotic leakage. There were no other complications. AB - CONCLUSIONS: Early urinary continence rates were high in patients undergoing single or double layer urethrovesical anastomosis. We found no improvement in early continence rates with reconstruction of the periprostatic tissues. ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(08)01282-2 DO - https://dx.doi.org/10.1016/j.juro.2008.05.046 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 18639300 [pubmed] ID - S0022-5347(08)01282-2 [pii] ID - 10.1016/j.juro.2008.05.046 [doi] PP - ppublish PH - 2008/01/30 [received] LG - English EP - 20080717 DP - 2008 Sep DC - 20080811 EZ - 2008/07/22 09:00 DA - 2008/09/19 09:00 DT - 2008/07/22 09:00 YR - 2008 ED - 20080918 RD - 20090327 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18639300 <501. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18355146 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Mendiola FP AU - Zorn KC AU - Mikhail AA AU - Lin S AU - Orvieto MA AU - Zagaja GP AU - Shalhav AL FA - Mendiola, Frederick P FA - Zorn, Kevin C FA - Mikhail, Albert A FA - Lin, Shang FA - Orvieto, Marcelo A FA - Zagaja, Gregory P FA - Shalhav, Arieh L IN - Mendiola, Frederick P. University of Chicago, Section of Urology, Chicago, Illinois, USA. doceric18th@yahoo.com TI - Urinary and sexual function outcomes among different age groups after robot-assisted laparoscopic prostatectomy. SO - Journal of Endourology. 22(3):519-24, 2008 Mar AS - J Endourol. 22(3):519-24, 2008 Mar NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Print JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Age Factors MH - Aged MH - *Erectile Dysfunction/et [Etiology] MH - Humans MH - Laparoscopy MH - Male MH - Middle Aged MH - Prospective Studies MH - *Prostatectomy/ae [Adverse Effects] MH - Quality of Life MH - Robotics MH - Surveys and Questionnaires MH - Treatment Outcome MH - *Urination Disorders/et [Etiology] AB - PURPOSE: We present an age-stratified prospective assessment of urinary and sexual function of 300 patients after robot-assisted laparoscopic prostatectomy (RALP). AB - MATERIALS AND METHODS: Subjective assessment data of continence and potency were collected for different age groups (<50, 50-59, and > or =60 years old) preoperatively, and at 1, 3, 6, and 12 months after RALP. Health-related quality of life questionnaires evaluated return of baseline urinary and sexual function at the same time intervals. AB - RESULTS: The three age groups included 21, 129, and 150 patients (aged <50, 50-59, and >60 years old, respectively). Using Kaplan-Meier curves, younger men achieved subjective continence significantly earlier than older age groups when age groups were compared using a 60-year-old cut-off point (P = 0.02). However, subjective continence was noted to be equal among all age groups after 1 year of follow-up. Time to recovery of subjective potency among age groups shows a significant difference in favor of the younger age group (P = 0.01) Objective urinary function is equal between age groups at all time points, while objective sexual function assessment showed a trend toward better results in the younger age group. AB - CONCLUSIONS: Younger men will likely have an earlier return of continence and potency compared to older men after RALP. However, continence outcomes were noted to be equal among age groups after I year of follow-up, while younger men continue to report superior potency outcomes compared to older men over the first postoperative year. Such findings are valuable in counseling older men undergoing this procedure. IS - 0892-7790 IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2006.9845 PT - Clinical Trial PT - Journal Article ID - 18355146 [pubmed] ID - 10.1089/end.2006.9845 [doi] PP - ppublish LG - English DP - 2008 Mar DC - 20080321 EZ - 2008/03/22 09:00 DA - 2008/09/19 09:00 DT - 2008/03/22 09:00 YR - 2008 ED - 20080918 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18355146 <502. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18567884 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ruckert JC AU - Ismail M AU - Swierzy M AU - Sobel H AU - Rogalla P AU - Meisel A AU - Wernecke KD AU - Ruckert RI AU - Muller JM FA - Ruckert, Jens C FA - Ismail, Mahmoud FA - Swierzy, Marc FA - Sobel, Holger FA - Rogalla, Patrik FA - Meisel, Andreas FA - Wernecke, Klaus D FA - Ruckert, Ralph I FA - Muller, Joachim M IN - Ruckert, Jens C. Klinik fur Allgemein-, Viszeral-, Gefass- und Thoraxchirurgie, Charite-Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany. jens-c.rueckert@charite.de TI - Thoracoscopic thymectomy with the da Vinci robotic system for myasthenia gravis. SO - Annals of the New York Academy of Sciences. 1132:329-35, 2008 AS - Ann N Y Acad Sci. 1132:329-35, 2008 NJ - Annals of the New York Academy of Sciences PI - Journal available in: Print PI - Citation processed from: Print JC - 5nm, 7506858 IO - Ann. N. Y. Acad. Sci. SB - Index Medicus CP - United States MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Child MH - Child, Preschool MH - Female MH - Humans MH - Male MH - Middle Aged MH - Myasthenia Gravis/cl [Classification] MH - Myasthenia Gravis/pa [Pathology] MH - *Myasthenia Gravis/su [Surgery] MH - *Thoracoscopy/mt [Methods] MH - *Thymectomy AB - Complete thymectomy (Thx) is a crucial part of treatment for myasthenia gravis (MG) and thymoma. The discussion about the necessity of radical, complete Thx and reduced invasiveness has led to no less than 14 different surgical approaches for Thx. The latest development is robotic-assisted surgery. Though its impact on minimally invasive surgery is not yet clear, it seems to be most promising for surgery in remote, narrow anatomical regions like the mediastinum. One hundred six consecutive robotic-assisted thymectomies (rThx) with the da Vinci robotic surgical system were performed between January 2003 and April 2007 in a prospective single-center study. Postoperative morbidity was recorded according to the Myasthenia Gravis Foundation of America (MGFA) classification. With zero mortality, the overall postoperative morbidity rate was 2%. The cumulative complete stable remission rate of MG was > 40% for all patients, and there was no statistical difference as compared to non-thymomatous MG patients. The cumulative rate of minimal manifestations (MM0-MM3) according to the MGFA classification showed a postoperative improvement in quality of life for most of the patients. The da Vinci robotic system allowed for technical refinements of the well-defined operation technique of thoracoscopic Thx (tThx). From the technical point of view, rThx has advantages for mediastinal dissection. rThx had a shorter learning curve. There might be better outcome results for rThx in MG patients, as compared with nonrobotic tThx. Therefore, rThx is a promising technique for minimally invasive Thx. IS - 0077-8923 IL - 0077-8923 DI - 1132/1/329 DO - https://dx.doi.org/10.1196/annals.1405.013 PT - Clinical Trial PT - Journal Article ID - 18567884 [pubmed] ID - 1132/1/329 [pii] ID - 10.1196/annals.1405.013 [doi] PP - ppublish LG - English DP - 2008 DC - 20080623 EZ - 2008/06/24 09:00 DA - 2008/09/09 09:00 DT - 2008/06/24 09:00 YR - 2008 ED - 20080908 RD - 20080623 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18567884 <503. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18520226 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Breitenstein S AU - Nocito A AU - Puhan M AU - Held U AU - Weber M AU - Clavien PA FA - Breitenstein, Stefan FA - Nocito, Antonio FA - Puhan, Milo FA - Held, Ulrike FA - Weber, Markus FA - Clavien, Pierre-Alain IN - Breitenstein, Stefan. Swiss HPB (Hepato-Pancreato-Biliary) Center, University Hospital of Zurich, Zurich, Switzerland. TI - Robotic-assisted versus laparoscopic cholecystectomy: outcome and cost analyses of a case-matched control study. SO - Annals of Surgery. 247(6):987-93, 2008 Jun AS - Ann Surg. 247(6):987-93, 2008 Jun NJ - Annals of surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 67s, 0372354 IO - Ann. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Case-Control Studies MH - Cholecystectomy, Laparoscopic/ec [Economics] MH - *Cholecystectomy, Laparoscopic MH - Cost-Benefit Analysis MH - Female MH - Hospital Costs MH - Humans MH - Male MH - Middle Aged MH - Postoperative Complications MH - Prospective Studies MH - Regression Analysis MH - Robotics/ec [Economics] MH - *Robotics MH - Treatment Outcome AB - OBJECTIVE: To compare safety and costs of robotic-assisted and laparoscopic cholecystectomy in patients with symptomatic cholecystolithiasis. AB - BACKGROUND: Technical benefits of robotic-assisted surgery are well documented. However, pressure is currently applied to decrease costs, leading to restriction of development, and implementation of new technologies. So far, no convincing data are available comparing outcome or costs between computer assisted and conventional laparoscopic cholecystectomy. AB - METHODS: A prospective case-matched study was conducted on 50 consecutive patients, who underwent robotic-assisted cholecystectomy (Da Vinci Robot, Intuitive Surgical) between December 2004 and February 2006. These patients were matched 1:1 to 50 patients with conventional laparoscopic cholecystectomy, according to age, gender, American Society of Anesthesiologists score, histology, and surgical experience. Endpoints were complications after surgery (mean follow-up of 12.3 months [SD 1.2]), conversion rates, operative time, and hospital costs (ClinicalTrial.gov ID: NCT00562900). AB - RESULTS: No minor, but 1 major complication occurred in each group (2%). No conversion to open surgery was needed in either group. Operation time (skin-to-skin, 55 minutes vs. 50 minutes, P < 0.85) and hospital stay (2.6 days vs. 2.8 days) were similar. Overall hospital costs were significantly higher for robotic-assisted cholecystectomy $7985.4 (SD 1760.9) versus $6255.3 (SD 1956.4), P < 0.001, with a raw difference of $1730.1(95% CI 991.4-2468.7) and a difference adjusted for confounders of $1606.4 (95% CI 1076.7-2136.2). This difference was mainly related to the amortization and consumables of the robotic system. AB - CONCLUSIONS: Robotic-assisted cholecystectomy is safe and, therefore, a valuable approach. Costs of robots, however, are high and do not justify the use of this technology considering the lack of benefits for patients. A reduction of acquisition and maintenance costs for the robotic system is a prerequisite for large-scale adoption and implementation. ES - 1528-1140 IL - 0003-4932 DI - 00000658-200806000-00012 DO - https://dx.doi.org/10.1097/SLA.0b013e318172501f PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 18520226 [pubmed] ID - 10.1097/SLA.0b013e318172501f [doi] ID - 00000658-200806000-00012 [pii] PP - ppublish SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT00562900 SL - https://clinicaltrials.gov/search/term=NCT00562900 LG - English DP - 2008 Jun DC - 20080603 EZ - 2008/06/04 09:00 DA - 2008/06/27 09:00 DT - 2008/06/04 09:00 YR - 2008 ED - 20080626 RD - 20080603 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18520226 <504. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18270772 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Baik SH AU - Ko YT AU - Kang CM AU - Lee WJ AU - Kim NK AU - Sohn SK AU - Chi HS AU - Cho CH FA - Baik, S H FA - Ko, Y T FA - Kang, C M FA - Lee, W J FA - Kim, N K FA - Sohn, S K FA - Chi, H S FA - Cho, C H IN - Baik, S H. Robotic and Laparoscopic Surgery Center, Severance Hospital, Seoul, Korea. whitenoja@yumc.yonsei.ac.kr TI - Robotic tumor-specific mesorectal excision of rectal cancer: short-term outcome of a pilot randomized trial. SO - Surgical Endoscopy. 22(7):1601-8, 2008 Jul AS - Surg Endosc. 22(7):1601-8, 2008 Jul NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adult MH - Aged MH - Back Pain/et [Etiology] MH - Blood Loss, Surgical MH - Edema/et [Etiology] MH - Female MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy MH - Length of Stay MH - Lymph Node Excision MH - Male MH - Middle Aged MH - Neoplasm Staging MH - Rectal Neoplasms/pa [Pathology] MH - *Rectal Neoplasms/su [Surgery] MH - *Robotics AB - BACKGROUND: Laparoscopic colorectal resection has become popular. The recently developed da Vinci Surgical System promises to facilitate endoscopic surgery and overcome its disadvantages. This study therefore aimed to compare the short-term results between robotic tumor-specific mesorectal excision (R-TSME) using the da Vinci Surgical System and conventional laparoscopic tumor-specific mesorectal excision (L-TSME) in rectal cancer patients. AB - METHODS: Between April 2006 and February 2007, 36 patients were randomly assigned to receive R-TSME or L-TSME. During the study, 18 patients underwent robotic low anterior resection using the da Vinci Surgical System, and 18 patients had conventional laparoscopic low anterior resection. Patient characteristics, perioperative clinical results, complications, and pathologic details were compared between the two groups. AB - RESULTS: The patient characteristics were not significantly different between the two groups. The mean operating time, hemoglobin change, and conversion rate were not significantly different between the groups. Complications were treated conservatively and did not require surgical intervention in the R-TSME group. The average length of stay was 6.9 +/- 1.3 days in the R-TSME group and 8.7 +/- 1.3 days in the L-TSME group (p < 0.001). The specimen quality of the R-TSME group was acceptable. AB - CONCLUSION: Tumor-specific mesorectal excision was performed safely and effectively using the da Vinci Surgical System and the perioperative outcomes were acceptable. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-008-9752-z PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 18270772 [pubmed] ID - 10.1007/s00464-008-9752-z [doi] PP - ppublish PH - 2007/05/29 [received] PH - 2007/11/28 [accepted] PH - 2007/08/21 [revised] LG - English EP - 20080213 DP - 2008 Jul DC - 20080609 EZ - 2008/02/14 09:00 DA - 2008/06/27 09:00 DT - 2008/02/14 09:00 YR - 2008 ED - 20080626 RD - 20080609 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18270772 <505. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17995993 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Meyer C AU - Ulbricht S AU - Baumeister SE AU - Schumann A AU - Ruge J AU - Bischof G AU - Rumpf HJ AU - John U FA - Meyer, Christian FA - Ulbricht, Sabina FA - Baumeister, Sebastian E FA - Schumann, Anja FA - Ruge, Jeannette FA - Bischof, Gallus FA - Rumpf, Hans-Jurgen FA - John, Ulrich IN - Meyer, Christian. Department of Epidemiology and Social Medicine, University of Greifswald, Greifswald, Germany. chmeyer@uni-greifswald.de TI - Proactive interventions for smoking cessation in general medical practice: a quasi-randomized controlled trial to examine the efficacy of computer-tailored letters and physician-delivered brief advice. CM - Comment in: Addiction. 2008 Feb;103(2):307-8; discussion 309; PMID: 18199309 CM - Comment in: Addiction. 2008 Feb;103(2):305-6; discussion 309; PMID: 18199308 SO - Addiction. 103(2):294-304, 2008 Feb AS - Addiction. 103(2):294-304, 2008 Feb NJ - Addiction (Abingdon, England) PI - Journal available in: Print-Electronic PI - Citation processed from: Print JC - bm3, 9304118 IO - Addiction PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253708 SB - Index Medicus CP - England MH - Adolescent MH - Adult MH - Aged MH - Computers MH - *Correspondence as Topic MH - *Counseling MH - Family Practice/sn [Statistics & Numerical Data] MH - *Family Practice MH - Female MH - Germany MH - Humans MH - Male MH - Middle Aged MH - *Patient Education as Topic/mt [Methods] MH - Patient Education as Topic/sn [Statistics & Numerical Data] MH - Self Care/mt [Methods] MH - *Smoking Cessation/mt [Methods] MH - Smoking Cessation/sn [Statistics & Numerical Data] AB - AIMS: To test the efficacy of (i) computer-generated tailored letters and (ii) practitioner-delivered brief advice for smoking cessation against an assessment-only condition; and to compare both interventions directly. AB - DESIGN: Quasi-randomized controlled trial. AB - SETTING: A total of 34 randomly selected general practices from a German region (participation rate 87%). AB - PARTICIPANTS: A total of 1499 consecutive patients aged 18-70 years with daily cigarette smoking (participation rate 80%). AB - INTERVENTIONS: The tailored letters intervention group received up to three individualized personal letters. Brief advice was delivered during routine consultation by the practitioner after an onsite training session. Both interventions were based on the Transtheoretical Model of behaviour change. AB - MEASUREMENTS: Self-reported point prevalence and prolonged abstinence at 6-, 12-, 18- and 24-month follow-ups. AB - FINDINGS: Among participants completing the last follow-up, 6-month prolonged abstinence was 18.3% in the tailored letters intervention group, 14.8% in the brief advice intervention group and 10.5% in the assessment-only control group. Assuming those lost to follow-up to be smokers, the rates were 10.2%, 9.7% and 6.7%, respectively. Analyses including all follow-ups confirmed statistically significant effects of both interventions compared to assessment only. Using complete case analysis, the tailored letters intervention was significantly more effective than brief advice for 24-hour [odds ratio (OR) = 1.4; P = 0.047] but not for 7-day point prevalence abstinence (OR = 1.4; P = 0.068) for prolonged abstinence, or for alternative assumptions about participants lost to follow-up. AB - CONCLUSIONS: The study demonstrated long-term efficacy of low-cost interventions for smoking cessation in general practice. The interventions are suitable to reach entire populations of general practices and smoking patients. Computer-generated letters are a promising option to overcome barriers to provide smoking cessation counselling routinely. IS - 0965-2140 IL - 0965-2140 DI - ADD2031 DO - https://dx.doi.org/10.1111/j.1360-0443.2007.02031.x PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 17995993 [pubmed] ID - ADD2031 [pii] ID - 10.1111/j.1360-0443.2007.02031.x [doi] ID - PMC2253708 [pmc] PP - ppublish LG - English EP - 20071108 DP - 2008 Feb DC - 20080117 EZ - 2007/11/13 09:00 DA - 2008/06/11 09:00 DT - 2007/11/13 09:00 YR - 2008 ED - 20080610 RD - 20140904 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=17995993 <506. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18236302 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Schumann A AU - John U AU - Baumeister SE AU - Ulbricht S AU - Rumpf HJ AU - Meyer C FA - Schumann, Anja FA - John, Ulrich FA - Baumeister, Sebastian E FA - Ulbricht, Sabina FA - Rumpf, Hans-Jurgen FA - Meyer, Christian IN - Schumann, Anja. Division on Addictions, Cambridge Health Alliance, Medford, MA 02155, USA. aschumann@challiance.org TI - Computer-tailored smoking cessation intervention in a general population setting in Germany: outcome of a randomized controlled trial. SO - Nicotine & Tobacco Research. 10(2):371-9, 2008 Feb AS - Nicotine Tob Res. 10(2):371-9, 2008 Feb NJ - Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco PI - Journal available in: Print PI - Citation processed from: Print JC - drz, 9815751 IO - Nicotine Tob. Res. SB - Index Medicus CP - England MH - Adult MH - Aged MH - Counseling/mt [Methods] MH - Female MH - Follow-Up Studies MH - Germany MH - *Health Knowledge, Attitudes, Practice MH - Humans MH - *Internet/ut [Utilization] MH - Male MH - Middle Aged MH - Multivariate Analysis MH - *Patient Education as Topic/mt [Methods] MH - Program Evaluation MH - Regression Analysis MH - *Smoking/pc [Prevention & Control] MH - *Smoking Cessation/mt [Methods] MH - *Therapy, Computer-Assisted/mt [Methods] MH - Treatment Outcome AB - This study reports the outcome of a randomized controlled trial testing a computer-tailored smoking cessation intervention based on the transtheoretical model in a general population setting in Germany. Participants of the smoking intervention study were recruited from an existing general population health examination survey in a university hospital. The sample consisted of 611 current and former smokers at baseline, and of 485 participants in the core group of baseline daily cigarette smokers. Follow-ups were conducted 6, 12, 18, and 24 months after baseline. The intervention was designed for both current and former smokers, involved up to three individualized feedback letters, and was created using expert-system technology. Based on 7-day point-prevalence abstinence and 6-month prolonged abstinence as the outcome measures, the study identified no significant differences between the intervention and control groups. Modeling the full longitudinal data in generalized estimation equation analyses, using different nonresponse procedures, and adjusting for covariates did not alter the results. We conclude that the computer-tailored transtheoretical model-based smoking cessation intervention, as delivered in this study and in this special setting, was ineffective. IS - 1462-2203 IL - 1462-2203 DI - 790124116 DO - https://dx.doi.org/10.1080/14622200701825767 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 18236302 [pubmed] ID - 790124116 [pii] ID - 10.1080/14622200701825767 [doi] PP - ppublish LG - English DP - 2008 Feb DC - 20080131 EZ - 2008/02/01 09:00 DA - 2008/06/05 09:00 DT - 2008/02/01 09:00 YR - 2008 ED - 20080603 RD - 20080131 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18236302 <507. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18391295 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lendvay TS AU - Casale P AU - Sweet R AU - Peters C FA - Lendvay, Thomas S FA - Casale, Pasquale FA - Sweet, Robert FA - Peters, Craig IN - Lendvay, Thomas S. American Urological Association Office of Education, Baltimore, MD, USA. thomas.lendvay@seattlechildrens.org TI - VR robotic surgery: randomized blinded study of the dV-Trainer robotic simulator. SO - Studies in Health Technology & Informatics. 132:242-4, 2008 AS - Stud Health Technol Inform. 132:242-4, 2008 NJ - Studies in health technology and informatics PI - Journal available in: Print PI - Citation processed from: Print JC - ck1, 9214582 IO - Stud Health Technol Inform SB - Health Technology Assessment Journals CP - Netherlands MH - *Computer Simulation MH - *General Surgery/ed [Education] MH - Humans MH - Pediatrics MH - *Robotics/st [Standards] MH - *User-Computer Interface AB - This research represents a randomized blinded pilot study to evaluate the acceptability and validity of a da Vinci robotic virtual reality simulator platform tested during a pediatric robotic surgery post-graduate course during the annual American Urological Association meeting in June 2007. Course enrollees performed robotic skills tasks on the da Vinci robot and on an offline dV-Trainer and course participant demographic and performance data were analyzed. The majority of learners believed that VR simulation is useful for teaching robotic skills, they believed that the offline trainer can teach robotic skills comparable to a dry lab robotics skills station, and the offline trainer was able to discriminate between experts and novices of robotic surgery, thereby meeting criteria for face, content, and construct validities. This is the first reported acceptability study of a VR robotic surgery simulator as compared to the da Vinci robot system. IS - 0926-9630 IL - 0926-9630 PT - Journal Article PT - Randomized Controlled Trial PT - Validation Studies ID - 18391295 [pubmed] PP - ppublish LG - English DP - 2008 DC - 20080408 EZ - 2008/04/09 09:00 DA - 2008/05/28 09:00 DT - 2008/04/09 09:00 YR - 2008 ED - 20080527 RD - 20081121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18391295 <508. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18391288 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kolga Schlickum M AU - Hedman L AU - Enochsson L AU - Kjellin A AU - Fellander-Tsai L FA - Kolga Schlickum, Marcus FA - Hedman, Leif FA - Enochsson, Lars FA - Kjellin, Ann FA - Fellander-Tsai, Li IN - Kolga Schlickum, Marcus. Dept. of Clinical Science, Intervention and Technology, CLINTEC, Karolinska Institutet, Stockholm, Sweden. marcus.schlickum.552@student.ki.se TI - Transfer of systematic computer game training in surgical novices on performance in virtual reality image guided surgical simulators. SO - Studies in Health Technology & Informatics. 132:210-5, 2008 AS - Stud Health Technol Inform. 132:210-5, 2008 NJ - Studies in health technology and informatics PI - Journal available in: Print PI - Citation processed from: Print JC - ck1, 9214582 IO - Stud Health Technol Inform SB - Health Technology Assessment Journals CP - Netherlands MH - Adult MH - *Computer Simulation MH - Female MH - *General Surgery/ed [Education] MH - Humans MH - Male MH - *Psychomotor Performance MH - *Surgery, Computer-Assisted MH - Sweden MH - *User-Computer Interface MH - *Video Games AB - We report on a pilot study that investigates the transfer effect of systematic computer game training on performance in image guided surgery. In a group of 22 surgical novices, subjects were matched and randomized into one group training with a 3-D first person shooter (FPS) game and one group training with a 2-D non-FPS game. We also included a control group. Subjects were tested pre- and post training in the MIST-VR and GI-Mentor surgical simulators. We found that subjects with past experience specific to FPS games were significantly better in performing the simulated endoscopy task, both regarding time and efficiency of screening, compared to subjects lacking FPS game experience. Furthermore subjects who underwent systematic FPS game training performed better in the MIST-VR than those training with a 2-D game. Our findings indicate a transfer effect and that experience of video games are important for training outcome in simulated surgical procedures. Video game training can become useful when designing future skills training curricula for surgeons. IS - 0926-9630 IL - 0926-9630 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 18391288 [pubmed] PP - ppublish LG - English DP - 2008 DC - 20080408 EZ - 2008/04/09 09:00 DA - 2008/05/28 09:00 DT - 2008/04/09 09:00 YR - 2008 ED - 20080527 RD - 20081121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18391288 <509. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18374052 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Nousiainen M AU - Brydges R AU - Backstein D AU - Dubrowski A FA - Nousiainen, Markku FA - Brydges, Ryan FA - Backstein, David FA - Dubrowski, Adam IN - Nousiainen, Markku. Department of Surgery and the Wilson Centre for Research in Education, University of Toronto, Faculty of Medicine, Toronto, Ontario, Canada. TI - Comparison of expert instruction and computer-based video training in teaching fundamental surgical skills to medical students. SO - Surgery. 143(4):539-44, 2008 Apr AS - Surgery. 143(4):539-44, 2008 Apr NJ - Surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vc3, 0417347 IO - Surgery SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aptitude MH - Clinical Competence MH - Competency-Based Education MH - *Computer-Assisted Instruction MH - Curriculum MH - Education MH - *Education, Medical, Undergraduate/mt [Methods] MH - Educational Measurement MH - *General Surgery/ed [Education] MH - Humans MH - Students, Medical MH - *Surgical Procedures, Operative/ed [Education] MH - *Suture Techniques/ed [Education] MH - Teaching MH - Video Recording AB - BACKGROUND: Practice using computer-based video instruction (CBVI) leads to improvements in surgical skills proficiency. This study investigated the benefits of the introduction of (a) learner-directed, interactive video training and (b) the addition of expert instruction on the learning and retention of the basic surgical skills of suturing and knot-tying in medical students. AB - METHODS: Using bench models, students were pre-tested on a suturing and knot-tying skill after viewing an instructional video. The students were then randomly assigned to three practice conditions: self-study with video; self-study with interactive video; or the combination of self-study with interactive video with the addition of subsequent expert instruction. All participants underwent 18 trials of practice in their assigned training condition. The effectiveness of training was assessed by an immediate post-test and a retention test one month later. Performance was evaluated using expert- and computer-based assessments. Data were analyzed using repeated-measures ANOVA. AB - RESULTS: There were no differences in expert- and computer-based assessments between groups at pre-test. Although all three groups demonstrated significant improvements on both measures between the pre- and post-tests as well as between pre-tests and retention-tests (P < .01), no significant differences were detected among the three groups. AB - CONCLUSION: This study shows that in surgical novices, neither the inclusion of expert instruction nor the addition of self-directed interaction with video leads to further improvements in skill development or retention. These findings further support the possible implementation of CBVI within surgical skills curricula. ES - 1532-7361 IL - 0039-6060 DI - S0039-6060(07)00756-8 DO - https://dx.doi.org/10.1016/j.surg.2007.10.022 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 18374052 [pubmed] ID - S0039-6060(07)00756-8 [pii] ID - 10.1016/j.surg.2007.10.022 [doi] PP - ppublish PH - 2007/06/28 [received] PH - 2007/10/24 [revised] PH - 2007/10/25 [accepted] LG - English EP - 20080130 DP - 2008 Apr DC - 20080331 EZ - 2008/04/01 09:00 DA - 2008/04/29 09:00 DT - 2008/04/01 09:00 YR - 2008 ED - 20080428 RD - 20081121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med6&AN=18374052 <510. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18200624 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Falabella A AU - Moore-Jeffries E AU - Sullivan MJ AU - Nelson R AU - Lew M FA - Falabella, Andres FA - Moore-Jeffries, Earl FA - Sullivan, Michael J FA - Nelson, Rebecca FA - Lew, Michael IN - Falabella, Andres. Department of Anesthesiology, City of Hope National Medical Center, Duarte, CA 91010-3000, USA. TI - Cardiac function during steep Trendelenburg position and CO2 pneumoperitoneum for robotic-assisted prostatectomy: a trans-oesophageal Doppler probe study. SO - The International Journal Of Medical Robotics + Computer Assisted Surgery: MRCAS. 3(4):312-5, 2007 Dec AS - Int J Med Robot. 3(4):312-5, 2007 Dec NJ - The international journal of medical robotics + computer assisted surgery : MRCAS PI - Journal available in: Print PI - Citation processed from: Internet JC - 101250764 IO - Int J Med Robot SB - Index Medicus CP - England MH - Aged MH - Blood Pressure/ph [Physiology] MH - *Carbon Dioxide MH - Echocardiography, Transesophageal MH - *Heart/ph [Physiology] MH - Heart Rate/ph [Physiology] MH - Humans MH - Male MH - Middle Aged MH - Pneumoperitoneum, Artificial/mt [Methods] MH - *Posture/ph [Physiology] MH - *Prostatectomy/mt [Methods] MH - *Robotics/mt [Methods] MH - *Surgery, Computer-Assisted/mt [Methods] AB - BACKGROUND: Haemodynamic changes associated with pneumoperitoneum and steep Trendelenburg position were investigated in non-obese, ASA I-II males, using general anaesthesia (sevoflurane in air/O2, 40%) undergoing robotic-assisted laparoscopic prostatectomy. AB - METHODS: A trans-oesophageal echo-Doppler probe (Arrow International) measured cardiovascular changes in heart rate (HR), mean arterial pressure (MAP), cardiac output (CO), systemic vascular resistance (SVR), stroke volume (SV) and aortic diameter (AoD) in 35 of 37 males. Assessments were conducted after induction of general anaesthesia in: the supine position; at 45 degrees Trendelenburg; Trendelenburg + pnuemoperitoneum (intra-abdominal 15 mmHg); and at the end of surgery in the supine position. AB - RESULTS: The Trendelenburg position increased stroke volume. Trendelenburg position + pneumoperitoneum increased MAP and SVR and decreased AoD. AB - CONCLUSIONS: Pneumoperitoneum and steep Trendelenburg position significantly increase MAP and SVR. Trendelenburg position increased stroke volume. Pneumoperitoneum decreases aortic diameter. No significant changes in cardiac output or stroke volume were noted. AB - Copyright (c) 2008 John Wiley & Sons, Ltd. RN - 142M471B3J (Carbon Dioxide) ES - 1478-596X IL - 1478-5951 DO - https://dx.doi.org/10.1002/rcs.165 PT - Clinical Trial PT - Journal Article ID - 18200624 [pubmed] ID - 10.1002/rcs.165 [doi] PP - ppublish LG - English DP - 2007 Dec DC - 20080123 EZ - 2008/01/18 09:00 DA - 2008/02/12 09:00 DT - 2008/01/18 09:00 YR - 2007 ED - 20080211 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=18200624 <511. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17948920 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Anderson C AU - Hellan M AU - Kernstine K AU - Ellenhorn J AU - Lai L AU - Trisal V AU - Pigazzi A FA - Anderson, C FA - Hellan, M FA - Kernstine, K FA - Ellenhorn, J FA - Lai, L FA - Trisal, V FA - Pigazzi, A IN - Anderson, C. Department of General and Oncologic Surgery, City of Hope, Duarte, CA, USA. TI - Robotic surgery for gastrointestinal malignancies. SO - The International Journal Of Medical Robotics + Computer Assisted Surgery: MRCAS. 3(4):297-300, 2007 Dec AS - Int J Med Robot. 3(4):297-300, 2007 Dec NJ - The international journal of medical robotics + computer assisted surgery : MRCAS PI - Journal available in: Print PI - Citation processed from: Internet JC - 101250764 IO - Int J Med Robot SB - Index Medicus CP - England MH - Adult MH - Aged MH - Aged, 80 and over MH - *Digestive System Surgical Procedures/mt [Methods] MH - Feasibility Studies MH - *Gastrointestinal Neoplasms/su [Surgery] MH - Humans MH - Middle Aged MH - Pilot Projects MH - *Robotics/mt [Methods] MH - *Surgery, Computer-Assisted/mt [Methods] MH - Treatment Outcome AB - BACKGROUND: This report describes our initial experience with the use of robotic-assisted surgery for the treatment of gastrointestinal (GI) malignancies. AB - METHODS: Between November 2004 and July 2007, 73 robotic procedures (26 female, 47 male) for GI cancer were performed and retrospectively reviewed. Procedures included 25 oesophagectomies, 11 gastrectomies and 37 rectal resections. The median body mass index (BMI) for this patient population was 26. AB - RESULTS: The median operative times for rectal, oesophageal and gastric resections were 285, 482 and 430 min, respectively. There were three conversions. Major postoperative morbidity was 16% for rectal, 32% for oesophageal and 9% for gastric procedures. The leak rate was 11% for rectal, 16% for oesophageal and 9% for gastric anastomoses. Median length of stay was 4, 11 and 5 days, respectively. The median number of lymph nodes harvested was 13, 22, and 26 for rectal, oesophageal and gastric lymphadenectomies, respectively. At a median follow-up of 9 months, one patient developed a port site recurrence; 30 day mortality was zero. AB - CONCLUSION: This initial experience suggests that the robotic approach is safe and feasible for a variety of radical oncological surgical procedures. AB - Copyright (c) 2007 John Wiley & Sons, Ltd. ES - 1478-596X IL - 1478-5951 DO - https://dx.doi.org/10.1002/rcs.155 PT - Clinical Trial PT - Journal Article ID - 17948920 [pubmed] ID - 10.1002/rcs.155 [doi] PP - ppublish LG - English DP - 2007 Dec DC - 20080123 EZ - 2007/10/24 09:00 DA - 2008/02/12 09:00 DT - 2007/10/24 09:00 YR - 2007 ED - 20080211 RD - 20080123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17948920 <512. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 18086962 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - O'Malley BW Jr AU - Weinstein GS FA - O'Malley, Bert W Jr FA - Weinstein, Gregory S IN - O'Malley, Bert W Jr. Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA 19104, USA. bert.omalley@uphs.upenn.edu TI - Robotic skull base surgery: preclinical investigations to human clinical application. SO - Archives of Otolaryngology -- Head & Neck Surgery. 133(12):1215-9, 2007 Dec AS - Arch Otolaryngol Head Neck Surg. 133(12):1215-9, 2007 Dec NJ - Archives of otolaryngology--head & neck surgery PI - Journal available in: Print PI - Citation processed from: Print JC - 8603209, alq IO - Arch. Otolaryngol. Head Neck Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Animals MH - Cysts/di [Diagnosis] MH - Cysts/su [Surgery] MH - Dogs MH - *Endoscopes MH - *Endoscopy/mt [Methods] MH - Equipment Design MH - Follow-Up Studies MH - Humans MH - Magnetic Resonance Imaging MH - Mouth MH - *Robotics/is [Instrumentation] MH - Skull Base Neoplasms/di [Diagnosis] MH - *Skull Base Neoplasms/su [Surgery] MH - Treatment Outcome AB - OBJECTIVE: To develop a minimally invasive surgical technique for the treatment of parapharyngeal space and infratemporal fossa skull base neoplasms using the technical and optical advantages of robotic surgical instrumentation. AB - DESIGN: A robotics skull base surgery program at the University of Pennsylvania, Philadelphia, was initiated in the fall of 2005. Six experimental procedures focusing on developing approaches to the parapharyngeal space and infratemporal fossa were performed on a total of 2 cadavers and 1 mongrel dog. Based on the preclinical work, transoral robotic surgery (TORS) was then performed in February 2007 on 1 human patient with a parapharyngeal to infratemporal fossa cystic neoplasm as part of a large prospective human trial. AB - SETTING: In each cadaver and in the dog, a TORS approach to parapharyngeal space and infratemporal fossa was performed bilaterally and in an approved training facility using the da Vinci Surgical System. For the human surgical case, a TORS approach was evaluated on one side for a benign neoplasm. The human patient underwent TORS of the parapharyngeal space and infratemporal fossa under an institutional review board-approved prospective clinical trial. AB - PATIENTS: For the human clinical trial, a TORS approach was evaluated for a patient with a benign neoplasm of the parapharyngeal space and infratemporal fossa. AB - MAIN OUTCOME MEASURES: The ability to access and dissect tissues within the various areas of the parapharynx and infratemporal fossa was evaluated, and techniques to enhance visualization and instrumentation were developed. AB - RESULTS: Using TORS approaches permitted excellent access, visualization, and tissue dissection within the parapharyngeal space and infratemporal fossa in both the cadaver and canine experiments. In the first known human surgical case, TORS was used to remove a parapharyngeal space and infratemporal fossa cystic neoplasm. Wide visualization, followed by complete resection using the identical techniques developed in the preclinical models, was achieved. The robotic procedure allowed adequate and safe identification of the internal carotid artery and cranial nerves, and excellent hemostasis was achieved with no complications during or after surgery. AB - CONCLUSIONS: The TORS approaches provided excellent 3-dimensional visualization and instrument access that allowed successful parapharyngeal space and infratemporal fossa surgical resections from cadaver models to the first known human patient application. Robotic surgery for the skull base holds potential as a minimally invasive approach to skull base neoplasms; however, continued development and investigation is warranted in a prospective human clinical trial before final conclusions can be drawn as to the full advantages and limitations of this approach. IS - 0886-4470 IL - 0886-4470 DI - 133/12/1215 DO - https://dx.doi.org/10.1001/archotol.133.12.1215 PT - Clinical Trial PT - Journal Article ID - 18086962 [pubmed] ID - 133/12/1215 [pii] ID - 10.1001/archotol.133.12.1215 [doi] PP - ppublish LG - English DP - 2007 Dec DC - 20071218 EZ - 2007/12/19 09:00 DA - 2008/02/06 09:00 DT - 2007/12/19 09:00 YR - 2007 ED - 20080205 RD - 20071218 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=18086962 <513. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17949325 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Capello SA AU - Boczko J AU - Patel HR AU - Joseph JV FA - Capello, Seth A FA - Boczko, Judd FA - Patel, Hitendra R H FA - Joseph, Jean V IN - Capello, Seth A. Department of Urology, University of Rochester, Rochester, New York 14642, USA. TI - Randomized comparison of extraperitoneal and transperitoneal access for robot-assisted radical prostatectomy. SO - Journal of Endourology. 21(10):1199-202, 2007 Oct AS - J Endourol. 21(10):1199-202, 2007 Oct NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Print JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Blood Loss, Surgical/sn [Statistics & Numerical Data] MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - Postoperative Complications MH - *Prostatectomy/mt [Methods] MH - *Robotics/mt [Methods] MH - Time Factors MH - Treatment Outcome AB - PURPOSE: Although extraperitoneal robot-assisted radical prostatectomy (RARP) is gaining popularity, the majority of these procedures are performed transperitoneally. The purpose of this study was to compare the transperitoneal and extraperitoneal approaches for RARP. AB - PATIENTS AND METHODS: We randomized 62 consecutive patients undergoing RARP into two equal groups according to the route of access. The groups were evaluated for age, body mass index (BMI), preoperative serum prostate specific antigen (PSA) concentration, total operating time, estimated blood loss, specimen weight, pathologic Gleason score and stage, intraoperative and postoperative complications, and surgical-margin status. AB - RESULTS: No significant differences were noted the extraperitoneal and transperitoneal groups with respect total operative time (181 v 191 minutes), blood loss (199 v 163 mL), pathologic Gleason score (6.6 v 6.7), specimen weight (53 v 48 g), or positive-margin status (0 v 1 patient). There were no significant differences in age (56 v 59 years) or PSA (7.8 v 6.1 ng/dL). However, the BMI was significantly higher in the extraperitoneal group (29.8 v 26.5 kg/m(2); P < 0.01). The only complication in the study was a urine leak, which occurred in the transperitoneal group and was managed conservatively. AB - CONCLUSIONS: There were no significant differences in operative parameters in the two groups. Choice of access should be based on patient characteristics as well as surgeon preference. Patients who have had abdominal operations are best suited for the extraperitoneal route. Surgeons should be familiar with both approaches in order to provide patients with the best care. IS - 0892-7790 IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2007.9906 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 17949325 [pubmed] ID - 10.1089/end.2007.9906 [doi] PP - ppublish LG - English DP - 2007 Oct DC - 20071022 EZ - 2007/10/24 09:00 DA - 2008/01/25 09:00 DT - 2007/10/24 09:00 YR - 2007 ED - 20080124 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17949325 <514. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17867937 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Martinez-Salamanca JI AU - Rao S AU - Ramanathan R AU - Gonzalez J AU - Mandhani A AU - Yang X AU - Tu J AU - Vaughan ED AU - Tewari A FA - Martinez-Salamanca, Juan I FA - Rao, Sandhya FA - Ramanathan, Rajan FA - Gonzalez, Javier FA - Mandhani, Anil FA - Yang, Ximing FA - Tu, Jiangling FA - Vaughan, E Darracott FA - Tewari, Ashutosh IN - Martinez-Salamanca, Juan I. Weill Medical College of Cornell University, New York, New York, USA. TI - Nerve advancement with end-to-end reconstruction after partial neurovascular bundle resection:a feasibility study. SO - Journal of Endourology. 21(8):830-5, 2007 Aug AS - J Endourol. 21(8):830-5, 2007 Aug NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Print JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Aged MH - Erectile Dysfunction/pc [Prevention & Control] MH - Feasibility Studies MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Pilot Projects MH - Postoperative Complications/pc [Prevention & Control] MH - Prospective Studies MH - Prostate/ir [Innervation] MH - Prostate/su [Surgery] MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - *Reconstructive Surgical Procedures/mt [Methods] MH - Recovery of Function MH - *Robotics MH - Treatment Outcome AB - BACKGROUND AND PURPOSE: It is clear that some patients with prostate cancer require a total or partial neurovascular bundle (NVB) resection for oncologic safety to be guaranteed. Nerve grafting is an alternative for these patients to maintain erectile function; however, we report on a feasible option where the NVB is released, and both terminal nerve fibers are approximated; this is the "nerve advancement technique (NAT)." AB - PATIENTS AND METHODS: Since 2005, a total of 215 men aged 48 to 70 years (mean 59 years) with a Sexual Health Inventory for Men (SHIM) score of 22 have undergone robotic radical prostatectomy for cancer. We selected prospectively seven men to have NAT performed because of clinical high-risk criteria (serum prostate specific antigen [PSA] concentration >20 mg/dL, Gleason score = 8, and stage cT(2c) or higher), intraoperative criteria (difficulty separating the tissues around the prostate), and evidence of extracapsular extension (ECE) on magnetic resonance imaging. We performed unilateral partial resection, nerve advancement, and, finally, end-to-end anastomosis in six patients, whereas in one patient, we did a bilateral partial excision. We analyzed the results in terms of oncologic safety (positive surgical margins and PSA) and SHIM score after 18 months of follow-up. AB - RESULTS: Pathologic examination revealed stage T3 disease in six patients; one had a positive surgical margin. Two patients are receiving salvage radiotherapy for PSA relapse, and five continue to have undetectable PSA concentrations after a median follow-up of 20 months. Five of the seven men recovered erectile potency with or without a phosphodiesterase inhibitor, and their median SHIM score is 18. AB - CONCLUSIONS: We are encouraged by the initial results of NAT. The procedure may be an alternative for men who require extensive NVB dissection. However, further experience, longer follow-up, and independent trials are necessary. IS - 0892-7790 IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2007.9946 PT - Clinical Trial PT - Journal Article ID - 17867937 [pubmed] ID - 10.1089/end.2007.9946 [doi] PP - ppublish LG - English DP - 2007 Aug DC - 20070917 EZ - 2007/09/18 09:00 DA - 2007/12/07 09:00 DT - 2007/09/18 09:00 YR - 2007 ED - 20071206 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17867937 <515. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17867934 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Aron M AU - Kaouk JH AU - Hegarty NJ AU - Colombo JR Jr AU - Haber GP AU - Chung BI AU - Zhou M AU - Gill IS FA - Aron, Monish FA - Kaouk, Jihad H FA - Hegarty, Nicholas J FA - Colombo, Jose Roberto Jr FA - Haber, Georges-Pascal FA - Chung, Benjamin I FA - Zhou, Ming FA - Gill, Inderbir S IN - Aron, Monish. Section of Laparoscopic and Robotic Surgery, Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44115, USA. TI - Second prize: preliminary experience with the Niris optical coherence tomography system during laparoscopic and robotic prostatectomy. SO - Journal of Endourology. 21(8):814-8, 2007 Aug AS - J Endourol. 21(8):814-8, 2007 Aug NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Print JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - Awards and Prizes MH - Erectile Dysfunction/pc [Prevention & Control] MH - Humans MH - Laparoscopy MH - Male MH - Postoperative Complications/pc [Prevention & Control] MH - Prostate/bs [Blood Supply] MH - Prostate/ir [Innervation] MH - Prostate/su [Surgery] MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotics MH - *Tomography, Optical Coherence/is [Instrumentation] AB - PURPOSE: To evaluate the feasibility of high-resolution optical coherence tomography (OCT) in the identification of neurovascular bundles (NVBs) during laparoscopic and robotic radical prostatectomy (LRP). AB - PATIENTS AND METHODS: Between November 2005 and March 2006, 24 patients undergoing transperitoneal laparoscopic or robotic radical prostatectomy were enrolled in this study. Once the bladder was taken down and the prostate mobilized, the Niris imaging system was deployed. In each patient, in-vivo images were obtained to determine the image characteristics of NVBs, adipose tissue, prostate capsule, and endopelvic fascia. The NVB was imaged again in vivo, after the prostate was excised. Ex-vivo images were obtained from the prostate surface to look for the presence or absence of the NVBs and correlated with the surgeon's assessment of the adequacy of nerve sparing. AB - RESULTS: From 24 patients, we obtained more than 300 OCT images of tissue structures including endopelvic fascia, prostate capsule, NVBs, fat, lateral pedicles, and lymphatics. These images were found to correlate independently with the surgeon's impression of the tissue being imaged. Preliminary comparison with parallel histologic evaluation was performed in four patients that suggested OCT could help to identify the NVBs and prostate capsule during LRP. AB - CONCLUSIONS: In our preliminary experience with the Niris system during LRP, OCT was able to image the NVB in all patients. This could enhance surgical precision during nerve sparing and positively impact potency rates after radical prostatectomy. Further research will be needed, including parallel histologic evaluation and follow-up, to validate the findings of OCT imaging. IS - 0892-7790 IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2006.9938 PT - Clinical Trial PT - Journal Article ID - 17867934 [pubmed] ID - 10.1089/end.2006.9938 [doi] PP - ppublish LG - English DP - 2007 Aug DC - 20070917 EZ - 2007/09/18 09:00 DA - 2007/12/07 09:00 DT - 2007/09/18 09:00 YR - 2007 ED - 20071206 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17867934 <516. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17924450 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Najmaldin A AU - Antao B FA - Najmaldin, A FA - Antao, B IN - Najmaldin, A. Department of Paediatric Surgery, St James's University Hospital, Leeds, UK. Azad.Najmaldin@leedsth.nhs.uk TI - Early experience of tele-robotic surgery in children. SO - The International Journal Of Medical Robotics + Computer Assisted Surgery: MRCAS. 3(3):199-202, 2007 Sep AS - Int J Med Robot. 3(3):199-202, 2007 Sep NJ - The international journal of medical robotics + computer assisted surgery : MRCAS PI - Journal available in: Print PI - Citation processed from: Internet JC - 101250764 IO - Int J Med Robot SB - Index Medicus CP - England MH - Adolescent MH - Child MH - Child, Preschool MH - Equipment Design MH - Equipment Failure Analysis MH - Female MH - Humans MH - *Laparoscopes MH - Laparoscopy/mt [Methods] MH - Laparoscopy/td [Trends] MH - Male MH - *Pediatrics/is [Instrumentation] MH - Pediatrics/mt [Methods] MH - Pediatrics/td [Trends] MH - Pilot Projects MH - *Robotics/is [Instrumentation] MH - Robotics/mt [Methods] MH - Robotics/td [Trends] MH - *Surgery, Computer-Assisted/is [Instrumentation] MH - Surgery, Computer-Assisted/mt [Methods] MH - Surgery, Computer-Assisted/td [Trends] MH - *Telemedicine/is [Instrumentation] MH - Telemedicine/mt [Methods] MH - Telemedicine/td [Trends] AB - BACKGROUND: The application of robotic technology in paediatric and adult surgery is limited. We report our early experience in children. AB - METHODS: Selected children from the age of 3 years who underwent da Vinci robotic surgery were included. All procedures were carried out by the senior author (A.N.), using three robotic ports and an accessory laparoscopic port if and when necessary. The telescope port was placed using an open technique and all port sites were closed in layers at the end of the procedure. Post-operatively all patients were offered overnight intravenous morphine. All data was collected prospectively. AB - RESULTS: During March 2006-July 2007 there were 50 procedures in 40 children: fundoplication (5), fundoplication and gastrostomy (6), Heller's myotomy and fundoplication (2), cholecystectomy (1), splenectomy (1), cholecystectomy and splenectomy (1), re-do rectal mobilization (1), excision of Mullerian remnant and bilateral orchidopexy (1), partial nephroureterectomy (1), nephroureterectomy (4), neprectomy (4) and transperitoneal pyeloplasty (13). The mean age was 10.2 (range 3-17) years. The mean docking time was 11.9 (range 4-20) min. Forty-seven procedures in 37 children were successfully completed. There were three conversions, one robot-related (mechanical failure) and two non-robot-related (severe adhesions, difficulty with placing a guide wire for nephrostent) but no other operative complications. Post-operative complications were not robot-related (one wound infection, one urine extravasation from a displaced ureteric stent). The mean hospital stay was 2.4 (range 1-6) days, and this was affected by the patients' pre-existing clinical and social conditions. AB - CONCLUSIONS: In children robotic surgery is safe and applicable to a wide range of surgical conditions. Further experience is required in order to establish its full potential. AB - Copyright 2007 John Wiley & Sons, Ltd. ES - 1478-596X IL - 1478-5951 DO - https://dx.doi.org/10.1002/rcs.150 PT - Clinical Trial PT - Journal Article ID - 17924450 [pubmed] ID - 10.1002/rcs.150 [doi] PP - ppublish LG - English DP - 2007 Sep DC - 20071015 EZ - 2007/10/10 09:00 DA - 2007/11/06 09:00 DT - 2007/10/10 09:00 YR - 2007 ED - 20071105 RD - 20071015 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17924450 <517. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17353978 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Muller-Stich BP AU - Reiter MA AU - Wente MN AU - Bintintan VV AU - Koninger J AU - Buchler MW AU - Gutt CN FA - Muller-Stich, B P FA - Reiter, M A FA - Wente, M N FA - Bintintan, V V FA - Koninger, J FA - Buchler, M W FA - Gutt, C N IN - Muller-Stich, B P. Department of Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany. TI - Robot-assisted versus conventional laparoscopic fundoplication: short-term outcome of a pilot randomized controlled trial. CM - Comment in: Surg Endosc. 2008 May;22(5):1407; PMID: 18363061 SO - Surgical Endoscopy. 21(10):1800-5, 2007 Oct AS - Surg Endosc. 21(10):1800-5, 2007 Oct NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adult MH - Aged MH - Female MH - *Fundoplication/mt [Methods] MH - *Gastroesophageal Reflux/su [Surgery] MH - Humans MH - *Laparoscopy MH - Male MH - Middle Aged MH - Pilot Projects MH - *Robotics MH - Time Factors MH - Treatment Outcome AB - BACKGROUND: Robotic technology represents the latest development in minimally-invasive surgery. Nevertheless, robotic-assisted surgery seems to have specific disadvantages such as an increase in costs and prolongation of operative time. A general clinical implementation of the technique would only be justified if a relevant improvement in outcome could be demonstrated. This is also true for laparoscopic fundoplication. The present study was designed to compare robotic-assisted (RALF) and conventional laparoscopic fundoplication (CLF) with the focus on operative time, costs und perioperative outcome. AB - METHODS: Forty patients with gastro-esophageal reflux disease were randomized to either RALF by use of the daVinci Surgical System or CLF. Nissen fundoplication was the standard anti-reflux procedure. Peri-operative data such as length of operative procedure, intra-and postoperative complications, length of hospital stay, overall costs and symptomatic short-term outcome were compared. AB - RESULTS: The total operative time was shorter for RALF compared to CLF (88 vs. 102 min; p = 0.033) consisting of a longer set-up (23 vs. 20 min; p = 0.050) but a shorter effective operative time (65 vs. 82 min; p = 0.006). Intraoperative complications included one pneumothorax and two technical problems in the RALF group and two bleedings in the CLF group. There were no conversions to an open approach. Mean length of hospital stay (2.8 vs. 3.3 days; p = 0.086) and symptomatic outcome thirty days postoperatively (10% vs. 15% with ongoing PPI therapy; p = 1.0 and 25% vs. 20% with persisting mild dysphagia; p = 1.0) was similar in both groups. Costs were higher for RALF than for CLF (3244 euros vs. 2743 euros, p = 0.003). AB - CONCLUSION: In comparison with CLF, operative time can be shorter for RALF if performed by an experienced team. However, costs are higher and short-term outcome is similar. Thus, RALF can not be favoured over CLF regarding perioperative outcome. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-007-9268-y PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 17353978 [pubmed] ID - 10.1007/s00464-007-9268-y [doi] PP - ppublish PH - 2006/12/22 [received] PH - 2006/12/29 [accepted] PH - 2006/12/22 [revised] LG - English EP - 20070313 DP - 2007 Oct DC - 20070913 EZ - 2007/03/14 09:00 DA - 2007/10/04 09:00 DT - 2007/03/14 09:00 YR - 2007 ED - 20071003 RD - 20090416 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17353978 <518. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17618782 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kho RM AU - Hilger WS AU - Hentz JG AU - Magtibay PM AU - Magrina JF FA - Kho, Rosanne M FA - Hilger, Wesley S FA - Hentz, Joseph G FA - Magtibay, Paul M FA - Magrina, Javier F IN - Kho, Rosanne M. Department of Obstetrics and Gynecology, Mayo Clinic, Scottsdale, AZ, USA. TI - Robotic hysterectomy: technique and initial outcomes.[Erratum appears in Am J Obstet Gynecol. 2007 Sep;197(3):332] SO - American Journal of Obstetrics & Gynecology. 197(1):113.e1-4, 2007 Jul AS - Am J Obstet Gynecol. 197(1):113.e1-4, 2007 Jul NJ - American journal of obstetrics and gynecology PI - Journal available in: Print PI - Citation processed from: Internet JC - 3ni, 0370476 IO - Am. J. Obstet. Gynecol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Evaluation Studies as Topic MH - Female MH - Humans MH - *Hysterectomy/is [Instrumentation] MH - Middle Aged MH - Postoperative Complications MH - Retrospective Studies MH - *Robotics MH - Treatment Outcome AB - A surgical robot can move in ways that the human wrist cannot. Is it a practical substitute for the conventional hands-on approach? ES - 1097-6868 IL - 0002-9378 DI - S0002-9378(07)00617-5 DO - https://dx.doi.org/10.1016/j.ajog.2007.05.005 PT - Clinical Trial PT - Journal Article ID - 17618782 [pubmed] ID - S0002-9378(07)00617-5 [pii] ID - 10.1016/j.ajog.2007.05.005 [doi] PP - ppublish PH - 2006/04/11 [received] PH - 2007/04/27 [revised] PH - 2007/05/01 [accepted] LG - English DP - 2007 Jul DC - 20070709 EZ - 2007/07/10 09:00 DA - 2007/09/07 09:00 DT - 2007/07/10 09:00 YR - 2007 ED - 20070906 RD - 20071115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17618782 <519. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17723822 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - de Canniere D AU - Wimmer-Greinecker G AU - Cichon R AU - Gulielmos V AU - Van Praet F AU - Seshadri-Kreaden U AU - Falk V FA - de Canniere, Didier FA - Wimmer-Greinecker, Gerhard FA - Cichon, Romuald FA - Gulielmos, Vassilios FA - Van Praet, Frank FA - Seshadri-Kreaden, Usha FA - Falk, Volkmar IN - de Canniere, Didier. Department of Cardiac Surgery at Erasme University Hospital, Brussels, Belgium. didier.decanniere@ulb.ac.be TI - Feasibility, safety, and efficacy of totally endoscopic coronary artery bypass grafting: multicenter European experience. SO - Journal of Thoracic & Cardiovascular Surgery. 134(3):710-6, 2007 Sep AS - J Thorac Cardiovasc Surg. 134(3):710-6, 2007 Sep NJ - The Journal of thoracic and cardiovascular surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - k9j, 0376343 IO - J. Thorac. Cardiovasc. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - *Coronary Artery Bypass/mt [Methods] MH - *Endoscopy MH - Europe MH - Feasibility Studies MH - Humans MH - Middle Aged MH - *Robotics MH - Safety AB - OBJECTIVE: The invention of robotic systems has begun a new era of endoscopic cardiac surgery. Reports on totally endoscopic coronary artery bypass grafting are limited, however, and data regarding feasibility, safety, and efficacy are needed to determine this technique's position in the therapeutic armamentarium. This study describes the largest multicenter experience in the literature with robotic totally endoscopic coronary artery bypass grafting specifically addressing procedural feasibility, safety, and efficacy. AB - METHODS: Between September 1998 and November 2002, a total of 228 patients with coronary artery disease were scheduled for totally endoscopic coronary artery bypass grafting with the da Vinci Surgical System (Intuitive Surgical Inc, Sunnyvale, Calif.) at five European institutions. Patients underwent totally endoscopic coronary artery bypass grafting with either an on-pump (group A, n = 117) or an off-pump approach (group B, n = 111). Patients underwent postoperative angiography or stress electrocardiography and were followed up for 6 months. AB - RESULTS: Procedural feasibility was demonstrated through the completion of 164 successful totally endoscopic cases. Sixty-four patients (group C, 28%) had conversion to nonrobotic procedures. Conversion rates decreased with time. The overall procedural efficacy, as defined by angiographic patency or lack of ischemic signs on stress electrocardiography, was 97%. The incidence of major adverse cardiac events within 6 months was 5%. AB - CONCLUSION: Both on- and off-pump totally endoscopic coronary artery bypass grafting are feasible, with a conversion rate that diminishes with increasing experience. Conversion does not adversely affect outcome and thus constitutes a safe alternative. Although target vessel reintervention may be slightly higher than that reported for open coronary artery bypass grafting, graft patency and major adverse cardiac events for both approaches are comparable to those reported in the Society of Thoracic Surgeons database, demonstrating the safety and efficacy of the totally endoscopic coronary artery bypass grafting procedure. ES - 1097-685X IL - 0022-5223 DI - S0022-5223(07)00844-6 DO - https://dx.doi.org/10.1016/j.jtcvs.2006.06.057 PT - Clinical Trial PT - Journal Article PT - Multicenter Study PT - Research Support, Non-U.S. Gov't ID - 17723822 [pubmed] ID - S0022-5223(07)00844-6 [pii] ID - 10.1016/j.jtcvs.2006.06.057 [doi] PP - ppublish PH - 2005/09/27 [received] PH - 2006/05/16 [revised] PH - 2006/06/09 [accepted] LG - English DP - 2007 Sep DC - 20070828 EZ - 2007/08/29 09:00 DA - 2007/09/06 09:00 DT - 2007/08/29 09:00 YR - 2007 ED - 20070905 RD - 20070828 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17723822 <520. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17572197 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kohl SK AU - Balaji KC AU - Smith LM AU - Wilson NP AU - Johansson SL AU - Sterrett SP AU - Abrahams NA FA - Kohl, Shane K FA - Balaji, Kethandapatti C FA - Smith, Lynette M FA - Wilson, Nicholas P FA - Johansson, Sonny L FA - Sterrett, Samuel P FA - Abrahams, Neil A IN - Kohl, Shane K. Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198, USA. TI - Clinical significance of benign glands at surgical margins in robotic radical prostatectomy specimens. SO - Urology. 69(6):1112-6, 2007 Jun AS - Urology. 69(6):1112-6, 2007 Jun NJ - Urology PI - Journal available in: Print PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Adenocarcinoma/me [Metabolism] MH - *Adenocarcinoma/pa [Pathology] MH - Adenocarcinoma/su [Surgery] MH - Aged MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Neoplasm Staging MH - *Prostate/pa [Pathology] MH - Prostate/su [Surgery] MH - Prostate-Specific Antigen/bl [Blood] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/me [Metabolism] MH - *Prostatic Neoplasms/pa [Pathology] MH - Prostatic Neoplasms/su [Surgery] MH - *Robotics MH - Treatment Outcome AB - OBJECTIVES: Completion of robotic radical prostatectomy compared with conventional open retropubic radical prostatectomy can result in different alterations in the prostatectomy specimens. One difference appears to be an increased incidence of benign glands at the margins, which has been associated with an increase in postoperative prostatic-specific antigen (PSA) levels. We compared the frequency and clinical significance of benign prostate glands at the surgical margins in radical prostatectomy specimens obtained by robotic versus open retropubic prostatectomy. AB - METHODS: We reviewed 38 consecutive prostatectomy specimens from patients with biopsy-proven prostate cancer. Of these 38 specimens, 25 (65%) were obtained by robotic resection and 13 (35%) by open retropubic prostatectomy. Each case was analyzed for Gleason score, pathologic stage, including margin status, and the presence or absence of benign glands at the surgical margin. The study endpoint was the postoperative serum PSA level. AB - RESULTS: A significantly greater incidence (P = 0.035) of benign glands at the surgical margins was found within the robotic group compared with the open retropubic prostatectomy group (54% versus 15%). With a median follow-up of 12.5 months for the robotic group and 24.5 months for the robotic prostatectomy group, only 2 patients, who also had had positive surgical margins, had a continued and persistent increase in the postoperative PSA level after an initial nadir. AB - CONCLUSIONS: The early clinical follow-up data of our study have suggested that patients undergoing robotic radical prostatectomy with negative surgical margins achieve a PSA nadir of less than 0.1 ng/mL, irrespective of the presence or absence of benign prostatic tissue at the surgical margins. RN - EC 3-4-21-77 (Prostate-Specific Antigen) ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(07)00288-9 DO - https://dx.doi.org/10.1016/j.urology.2007.02.048 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 17572197 [pubmed] ID - S0090-4295(07)00288-9 [pii] ID - 10.1016/j.urology.2007.02.048 [doi] PP - ppublish PH - 2006/02/28 [received] PH - 2007/01/16 [revised] PH - 2007/02/27 [accepted] LG - English DP - 2007 Jun DC - 20070618 EZ - 2007/06/19 09:00 DA - 2007/08/30 09:00 DT - 2007/06/19 09:00 YR - 2007 ED - 20070829 RD - 20070618 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17572197 <521. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17488138 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Scott A AU - Tinelli M AU - Bond C AU - Community Pharmacy Medicines Management Evaluation Team FA - Scott, Anthony FA - Tinelli, Michela FA - Bond, Christine FA - Community Pharmacy Medicines Management Evaluation Team IN - Scott, Anthony. Health Economics Research Unit, University of Aberdeen, Aberdeen, Scotland. TI - Costs of a community pharmacist-led medicines management service for patients with coronary heart disease in England: healthcare system and patient perspectives. SO - Pharmacoeconomics. 25(5):397-411, 2007 AS - Pharmacoeconomics. 25(5):397-411, 2007 NJ - PharmacoEconomics PI - Journal available in: Print PI - Citation processed from: Print JC - b1v, 9212404 IO - Pharmacoeconomics SB - Health Technology Assessment Journals CP - New Zealand MH - *Community Pharmacy Services/ec [Economics] MH - *Coronary Disease/dt [Drug Therapy] MH - *Coronary Disease/ec [Economics] MH - Costs and Cost Analysis MH - Data Collection MH - Delivery of Health Care/ec [Economics] MH - Drug Costs MH - England MH - Humans MH - Multicenter Studies as Topic MH - Patients MH - State Medicine/ec [Economics] AB - BACKGROUND: Coronary heart disease (CHD) is the most common cause of death in the UK. CHD cost the UK National Health Service (NHS) pound 3.5 billion in 2003. The economic impact of community pharmacists providing a medicines management service for patients with CHD has not been rigorously evaluated; the full economic costs of such interventions are rarely presented in the literature. AB - OBJECTIVE: To examine the incremental costs of a 1-year community pharmacist-led medicines management service for patients with CHD in the UK, from a healthcare system and patient perspective. AB - METHODS AND PARTICIPANTS: A cost-minimisation analysis was conducted alongside a multicentre randomised controlled trial. The primary study participants were patients with CHD identified from general practice computer records. Patients (intervention, n = 980; control, n = 500) from 38 general practices in nine geographical areas in the UK were included in the study. INTERVENTION AND OUTCOMES MEASURES: The intervention consisted of a review of pharmaceuticals and lifestyle advice by pharmacists in their premises, with recommendations communicated to the patient's GP. The main outcome measure was the incremental cost per patient in the intervention group compared with the control group. Annual costs ( pound, 2003/4 values) included the costs of the intervention (training and delivery costs), the usual costs of NHS treatment (costs of pharmaceuticals, GP and hospital visits) and costs borne by patients. Data were collected in the 12 months before and 12 months after the intervention. AB - RESULTS: The total NHS cost increased between baseline and follow-up in both groups (from pound 1243 to pound 1286 [3%] in the control group and from pound 1410 to pound 1433 [2%] in the intervention group). The greater cost in the intervention group largely reflects the additional cost of the pharmacist training and the time taken to deliver the intervention; the difference in costs between the intervention and control groups, after controlling for differences in costs at baseline at follow-up, was statistically significant (p = 0.001). The costs of pharmaceuticals was higher in the intervention group ( pound 769.20 vs pound 742.3; p = 0.04). According to the sensitivity analysis, the intervention cost would need to decrease by 35% to achieve equivalence between costs in each arm of the trial. Difference to costs of patients and their carers at follow-up were not statistically significant. AB - CONCLUSIONS: The introduction of a 1-year pharmacist-led medicines management service is likely to increase the total cost of CHD treatment and prevention from the healthcare perspective, as the cost of the intervention outweighed the observed reduction in the cost of drugs in the intervention group. No changes in costs from the patient perspective were found. IS - 1170-7690 IL - 1170-7690 DI - 2554 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 17488138 [pubmed] ID - 2554 [pii] PP - ppublish LG - English DP - 2007 DC - 20070509 EZ - 2007/05/10 09:00 DA - 2007/08/19 09:00 DT - 2007/05/10 09:00 YR - 2007 ED - 20070815 RD - 20071115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17488138 <522. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17571540 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Chirita V AU - Chirita R AU - Stefanescu C AU - Chele G AU - Ilinca M FA - Chirita, V FA - Chirita, Roxana FA - Stefanescu, C FA - Chele, Gabriela FA - Ilinca, M IN - Chirita, V. Gr. T. Popa University of Medicine and Pharmacy, Iasi School of Medicine. TI - Computer use and addiction in Romanian children and teenagers--an observational study. SO - Revista Medico-Chirurgicala a Societatii de Medici Si Naturalisti Din Iasi. 110(3):526-32, 2006 Jul-Sep AS - Rev Med Chir Soc Med Nat Iasi. 110(3):526-32, 2006 Jul-Sep NJ - Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi PI - Journal available in: Print PI - Citation processed from: Print JC - shp, 0413735 IO - Rev Med Chir Soc Med Nat Iasi SB - Index Medicus CP - Romania MH - Adolescent MH - *Behavior, Addictive/ep [Epidemiology] MH - Child MH - *Computers MH - Female MH - Humans MH - *Internet MH - Male MH - Romania/ep [Epidemiology] MH - Schools/sn [Statistics & Numerical Data] MH - *Students/sn [Statistics & Numerical Data] MH - Surveys and Questionnaires AB - The computer has provided some wonderful opportunities for our children. Although research on the effects of children's use of computer is still ambiguous, some initial indications of positive and negative effects are beginning t emerge. They commonly use computers for playing games, completing school assignments, email, and connecting to the Internet. This may sometimes come at the expense of other activities such as homework or normal social interchange. Although most children seem to naturally correct the problem, parents and educators must monitor the signs of misuse. Studies of general computer users suggest that some children's may experience psychological problems such as social isolation, depression, loneliness, and time mismanagement related to their computer use and failure at school. The purpose of this study is to investigate issues related to computer use by school students from 11 to 18 years old. The survey included a representative sample of 439 school students of ages 11 to 18. All of the students came from 3 gymnasium schools and 5 high schools of Iasi, Romania. The students answered to a questionnaire comprising 34 questions related to computer activities. The children's parents answered to a second questionnaire with the same subject. Most questions supposed to rate on a scale the frequency of occurrence of a certain event or issue; some questions solicited an open-answer or to choose an answer from a list. These were aimed at highlighting: (1) The frequency of computer use by the students; (2) The interference of excessive use with school performance and social life; (3) The identification of a possible computer addiction. The data was processed using the SPSS statistics software, version 11.0. Results show that the school students prefer to spend a considerable amount of time with their computers, over 3 hours/day. More than 65.7% of the students have a computer at home. More than 70% of the parents admit they do not or only occasionally discuss computer use with their children. This indicates the fact that, although they bought a computer for their children, they do not supervise the way it is used. The family is rather a passive presence, vaguely responsible and lacking involvement. But, the parents consider that, for better school results, their children should use their computers. This study tried to identify aspects of computer addiction in gymnasium and high school students, as well. IS - 0048-7848 IL - 0048-7848 PT - Journal Article PT - Multicenter Study ID - 17571540 [pubmed] PP - ppublish LG - English DP - 2006 Jul-Sep DC - 20070618 EZ - 2007/06/19 09:00 DA - 2007/08/08 09:00 DT - 2007/06/19 09:00 YR - 2006 ED - 20070807 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17571540 <523. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17272285 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Community Pharmacy Medicines Management Project Evaluation Team FA - Community Pharmacy Medicines Management Project Evaluation Team IN - , . Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, UK. TI - The MEDMAN study: a randomized controlled trial of community pharmacy-led medicines management for patients with coronary heart disease. SO - Family Practice. 24(2):189-200, 2007 Apr AS - Fam Pract. 24(2):189-200, 2007 Apr NJ - Family practice PI - Journal available in: Print-Electronic PI - Citation processed from: Print JC - 8500875, fam IO - Fam Pract SB - Index Medicus CP - England MH - Aged MH - *Community Pharmacy Services MH - *Coronary Artery Disease/dt [Drug Therapy] MH - England MH - Female MH - Health Status MH - Humans MH - Male MH - *Medication Systems/og [Organization & Administration] MH - Middle Aged MH - Pharmacists MH - Professional Role MH - Surveys and Questionnaires AB - BACKGROUND: There have been recent moves to extend the role of the community pharmacist to include medicine management. AB - METHODS: A randomized controlled trial was conducted in nine sites in England. Patients with coronary heart disease were identified from general practice computer systems, recruited and randomized (2:1) to intervention or control. The 12-month intervention comprised an initial consultation with a community pharmacist to review appropriateness of therapy, compliance, lifestyle, social and support issues. Control patients received standard care. The primary outcome measures were appropriate treatment [derived from the National Service Framework (NSF)], health status (SF-36, EQ-5D) and an economic evaluation. Secondary outcome measures were patient risk of cardiovascular death and satisfaction. AB - RESULTS: The study involved 1493 patients (980 intervention and 513 control), 62 pharmacists and 164 GPs. No statistically significant differences between intervention and control groups were shown at follow-up for any of the primary outcome measures such as numbers on aspirin or lifestyle measures. There were few differences in quality of life (SF-36) between the intervention and control groups at baseline or follow-up or with overall EQ-5D score over time. The total National Health Service cost increased between baseline and at 12 months in both groups but to a greater extent in the intervention group. Significant improvements were found in the satisfaction score for patients' most recent pharmacy visit for prescription medicines among the intervention group, compared with control group. Self-reported compliance was good for both groups at baseline and no significant differences were shown at follow-up. AB - CONCLUSION: There was no change in the proportion of patients receiving appropriate medication as defined by the NSF. The pharmacist-led service was more expensive than standard care. IS - 0263-2136 IL - 0263-2136 DI - cml075 DO - https://dx.doi.org/10.1093/fampra/cml075 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 17272285 [pubmed] ID - cml075 [pii] ID - 10.1093/fampra/cml075 [doi] PP - ppublish LG - English EP - 20070131 DP - 2007 Apr DC - 20070423 EZ - 2007/02/03 09:00 DA - 2007/07/12 09:00 DT - 2007/02/03 09:00 YR - 2007 ED - 20070711 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17272285 <524. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17197015 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Spittaels H AU - De Bourdeaudhuij I AU - Vandelanotte C FA - Spittaels, Heleen FA - De Bourdeaudhuij, Ilse FA - Vandelanotte, Corneel IN - Spittaels, Heleen. Policy Research Centre Sport, Physical Activity and Health, Belgium. TI - Evaluation of a website-delivered computer-tailored intervention for increasing physical activity in the general population. SO - Preventive Medicine. 44(3):209-17, 2007 Mar AS - Prev Med. 44(3):209-17, 2007 Mar NJ - Preventive medicine PI - Journal available in: Print-Electronic PI - Citation processed from: Print JC - pm4, 0322116 IO - Prev Med SB - Index Medicus CP - United States MH - Adult MH - Belgium MH - *Expert Systems MH - *Feedback MH - Female MH - *Health Behavior MH - *Health Education/mt [Methods] MH - *Health Promotion/mt [Methods] MH - Humans MH - *Internet MH - Male MH - Middle Aged MH - Motivation MH - *Motor Activity/ph [Physiology] MH - Program Evaluation MH - Reminder Systems AB - OBJECTIVE: To examine if a website-delivered physical activity intervention, that provides participants with computer-tailored feedback, can improve physical activity in the general population. AB - METHODS: Healthy adults (n=434), recruited from parents and staff of 14 primary and secondary schools in Belgium in the spring of 2005, were allocated into one of two intervention groups (receiving intervention with or without repeated feedback) or a no-intervention control group. Physical activity-levels were self-reported at baseline and at 6 months (n=285), using a computerized long version of the International Physical Activity Questionnaire online. Repeated measures analysis of co-variances were used to examine differences between the three groups. AB - RESULTS: Intent-to-treat analysis showed significant time by group interaction effects in favor of both intervention groups compared with the control group. Significant increases were found for active transportation (+20, +24, +11 min/week respectively) and leisure-time physical activity (+26, +19, -4 min/week respectively); a significant decrease for minutes sitting on weekdays (-22, -34, +4 min/day respectively). No significant differences were found between both intervention groups. AB - CONCLUSION: A website-delivered intervention, including computer-tailoring, was able to increase physical activity when compared to a no-intervention control group. High drop-out rate and the low number of participants who received repeated feedback indicated that engagement and retention are important challenges in e-health studies. IS - 0091-7435 IL - 0091-7435 DI - S0091-7435(06)00502-0 DO - https://dx.doi.org/10.1016/j.ypmed.2006.11.010 PT - Controlled Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 17197015 [pubmed] ID - S0091-7435(06)00502-0 [pii] ID - 10.1016/j.ypmed.2006.11.010 [doi] PP - ppublish PH - 2006/04/21 [received] PH - 2006/11/13 [revised] PH - 2006/11/14 [accepted] LG - English EP - 20070102 DP - 2007 Mar DC - 20070306 EZ - 2007/01/02 09:00 DA - 2007/06/21 09:00 DT - 2007/01/02 09:00 YR - 2007 ED - 20070620 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17197015 <525. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17520641 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Augustin F AU - Schmid T AU - Bodner J FA - Augustin, Florian FA - Schmid, Thomas FA - Bodner, Johannes IN - Augustin, Florian. Department of General, Thoracic and Transplant Surgery, Innsbruck Medical University, Innsbruck, Austria. TI - The robotic approach for mediastinal lesions. [Review] [31 refs] SO - The International Journal Of Medical Robotics + Computer Assisted Surgery: MRCAS. 2(3):262-70, 2006 Sep AS - Int J Med Robot. 2(3):262-70, 2006 Sep NJ - The international journal of medical robotics + computer assisted surgery : MRCAS PI - Journal available in: Print PI - Citation processed from: Internet JC - 101250764 IO - Int J Med Robot SB - Index Medicus CP - England MH - Adolescent MH - Adult MH - Aged MH - Female MH - Humans MH - Male MH - *Mediastinal Diseases/su [Surgery] MH - *Mediastinum/su [Surgery] MH - Middle Aged MH - *Minimally Invasive Surgical Procedures/mt [Methods] MH - *Robotics/mt [Methods] MH - *Surgery, Computer-Assisted/mt [Methods] MH - *Thoracic Surgical Procedures/mt [Methods] MH - Treatment Outcome AB - BACKGROUND: We report here our institutional experience and reflect the relevant literature concerning the robotic approach in diagnostic and therapeutic interventions for mediastinal lesions. AB - METHODS: During August 2001-December 2005, 33 patients (15 males and 18 females aged 18-77 years) with mediastinal masses were operated on minimally invasively using the da Vinci robotic system. There were 22 thymectomies (nine thymomas), four resections of paravertebral neurinomas, one ectopic mediastinal parathyroidectomy, one resection of a lymphangioma, one resection of ectopic goitre, one resection of lymph node metastasis of thyroid carcinoma and three oesophageal procedures (one leiomyoma, one traction diverticulum and one foregut cyst). AB - RESULTS: There were three (9%) open conversions due to surgical problems, 30 procedures (91%) were completed successfully using the da Vinci robot. There was no surgical mortality, no relevant intraoperative blood loss and no major surgical complication in any of the patients. As a minor complication (3%), an incomplete and transient palsy of the left laryngeal recurrent nerve was observed after resection of a tumour from the aortopulmonary window. The median overall operation time was 134 (range 54-314) min, including 103 (range 39-272) min for the robotic act. AB - CONCLUSIONS: Various different mediastinal procedures have been shown to be feasible and safe when performed with the robot. As the technical benefits of the da Vinci system are most advantageous in tiny and difficult-to-reach anatomical regions, the mediastinum should remain an area of special interest for robotic surgeons. Randomized trials and follow-up studies have been initiated in order to evaluate the clinical impact of the robotic approach. AB - Copyright 2006 John Wiley & Sons, Ltd. [References: 31] ES - 1478-596X IL - 1478-5951 DO - https://dx.doi.org/10.1002/rcs.84 PT - Clinical Trial PT - Journal Article PT - Review ID - 17520641 [pubmed] ID - 10.1002/rcs.84 [doi] PP - ppublish LG - English DP - 2006 Sep DC - 20070523 EZ - 2007/05/24 09:00 DA - 2007/06/20 09:00 DT - 2007/05/24 09:00 YR - 2006 ED - 20070619 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17520641 <526. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17380830 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Javer AR AU - Genoway KA FA - Javer, Amin R FA - Genoway, Krista A IN - Javer, Amin R. St. Paul's Sinus Centre, ENT Clinic, St. Paul's Hospital, Vancouver, British Columbia. sinussurgeon@shaw.ca TI - Patient quality of life improvements with and without computer assistance in sinus surgery: outcomes study. SO - Journal of Otolaryngology. 35(6):373-9, 2006 Dec AS - J Otolaryngol. 35(6):373-9, 2006 Dec NJ - The Journal of otolaryngology PI - Journal available in: Print PI - Citation processed from: Print JC - kbc, 7610513 IO - J Otolaryngol SB - Index Medicus CP - Canada MH - Adult MH - Aged MH - Aged, 80 and over MH - Chronic Disease MH - *Endoscopy/mt [Methods] MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Prospective Studies MH - *Quality of Life MH - Severity of Illness Index MH - Sinusitis/co [Complications] MH - *Sinusitis/su [Surgery] MH - *Surgery, Computer-Assisted MH - Treatment Outcome AB - BACKGROUND: Chronic rhinosinusitis affects millions of North Americans and has been increasing annually since 1991. This study aimed to evaluate the effectiveness of functional endoscopic sinus surgery (FESS) done with the use of computer assistance (CASS) and without the use of computer assistance on patient quality of life. As of this writing, there is no published study that measures the difference in patient quality of life with and without image guidance in endoscopic sinus surgery. AB - METHODS: A nonrandomized prospective study was performed on 95 patients. A 31-item quality of life (Rhinosinusitis Outcome Measures Form [RSOM-31]) questionnaire was administered to patients prior to surgery and 6 months following surgery during a 3-year enrollment period. Patients assessed both rhinologic and nonrhinologic symptoms using a statistically validated scoring system. Statistical analysis was performed using both equal and unequal variance sample t-tests when appropriate. AB - RESULTS: Statistically significant improvement in mean score analysis between preoperative and postoperative results for all symptom subgroups was reported when the entire study population was included. When the improvement in quality of life was compared between the CASS and FESS surgical groups, the CASS group demonstrated an overall greater improvement in quality of life. AB - CONCLUSION: Quality of life restrictions in patients with chronic rhinosinusitis were greatest in the areas of nasal symptoms and sleep deprivation, which were significantly improved by endoscopic sinus surgery. Although the long-term effect of CASS as measured by patient quality of life remains relatively unknown, there appears to be a significant trend indicating greater quality of life improvement in the short- term over non-computer-assisted FESS techniques. IS - 0381-6605 IL - 0381-6605 PT - Controlled Clinical Trial PT - Journal Article ID - 17380830 [pubmed] PP - ppublish LG - English DP - 2006 Dec DC - 20070326 EZ - 2007/03/27 09:00 DA - 2007/05/05 09:00 DT - 2007/03/27 09:00 YR - 2006 ED - 20070504 RD - 20070326 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17380830 <527. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17318044 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Heemskerk J AU - van Gemert WG AU - Greve JW AU - Bouvy ND FA - Heemskerk, Jeroen FA - van Gemert, Wim G FA - Greve, Jan Willem M FA - Bouvy, Nicole D IN - Heemskerk, Jeroen. Department of Surgery, Maastricht University Hospital, Maastricht, The Netherlands. Heemsch@hetnet.nl TI - Robot-assisted versus conventional laparoscopic Nissen fundoplication: a comparative retrospective study on costs and time consumption. SO - Surgical Laparoscopy, Endoscopy & Percutaneous Techniques. 17(1):1-4, 2007 Feb AS - Surg Laparosc Endosc Percutan Tech. 17(1):1-4, 2007 Feb NJ - Surgical laparoscopy, endoscopy & percutaneous techniques PI - Journal available in: Print PI - Citation processed from: Print JC - 100888751, dd2 IO - Surg Laparosc Endosc Percutan Tech SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Clinical Competence MH - Female MH - *Fundoplication/ec [Economics] MH - *Fundoplication/mt [Methods] MH - Health Care Costs MH - Humans MH - *Laparoscopy/ec [Economics] MH - Length of Stay MH - Male MH - Middle Aged MH - Netherlands MH - Retrospective Studies MH - *Robotics/ec [Economics] AB - BACKGROUND: Laparoscopic Nissen fundoplication offers clear benefits for our patients, but requires advanced laparoscopic skills. Robotic assistance in laparoscopic antireflux surgery improves dexterity skills and shortens learning curve, possibly leading to faster, more precise, and safer laparoscopic surgery. AB - METHODS: We review our first 11 cases of robot-assisted laparoscopic Nissen fundoplication using the 4-armed daVinci surgical system, comparing them with patients who underwent conventional laparoscopic Nissen fundoplication for gastroesophageal reflux disease in the same period. AB - RESULTS: Robot-assisted laparoscopic Nissen fundoplication did not result in more complications. However, the use of robotic assistance took an extra-47 minutes to complete the operation and costs were raised with an accessory euro 987.47. AB - CONCLUSIONS: The use of robotic assistance in laparoscopic antireflux surgery is safe and feasible, but results in longer operating time and higher costs compared with conventional laparoscopic surgery without proven benefit at this moment. IS - 1530-4515 IL - 1530-4515 DI - 00129689-200702000-00001 DO - https://dx.doi.org/10.1097/01.sle.0000213756.76761.b7 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 17318044 [pubmed] ID - 10.1097/01.sle.0000213756.76761.b7 [doi] ID - 00129689-200702000-00001 [pii] PP - ppublish LG - English DP - 2007 Feb DC - 20070223 EZ - 2007/02/24 09:00 DA - 2007/04/12 09:00 DT - 2007/02/24 09:00 YR - 2007 ED - 20070411 RD - 20070223 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17318044 <528. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17290690 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Blavier A AU - Gaudissart Q AU - Cadiere GB AU - Nyssen AS FA - Blavier, A FA - Gaudissart, Q FA - Cadiere, G B FA - Nyssen, A S IN - Blavier, A. National Fund of Scientific Research, University of Liege, Liege, Belgium. Adelaide.Blavier@ulg.ac.be TI - Impact of 2D and 3D vision on performance of novice subjects using da Vinci robotic system. SO - Acta Chirurgica Belgica. 106(6):662-4, 2006 Nov-Dec AS - Acta Chir Belg. 106(6):662-4, 2006 Nov-Dec NJ - Acta chirurgica Belgica PI - Journal available in: Print PI - Citation processed from: Print JC - 0370571 IO - Acta Chir. Belg. SB - Index Medicus CP - England MH - Consumer Behavior MH - Female MH - Humans MH - *Imaging, Three-Dimensional MH - Male MH - Minimally Invasive Surgical Procedures/ed [Education] MH - *Minimally Invasive Surgical Procedures/mt [Methods] MH - Motor Skills MH - Nursing Staff, Hospital/ed [Education] MH - *Robotics MH - Time Factors AB - PURPOSE OF THE STUDY: The aim of this study was to evaluate the impact of 3D and 2D vision on performance of novice subjects using da Vinci robotic system. AB - METHODS: 224 nurses without any surgical experience were divided into two groups and executed a motor task with the robotic system in 2D for one group and with the robotic system in 3D for the other group. Time to perform the task was recorded. AB - RESULTS: Our data showed significant better time performance in 3D view (24.67 +/- 11.2) than in 2D view (40.26 +/- 17.49, P < 0.001). AB - CONCLUSIONS: Our findings emphasized the advantage of 3D vision over 2D view in performing surgical task, encouraging the development of efficient and less expensive 3D systems in order to improve the accuracy of surgical gesture, the resident training and the operating time. IS - 0001-5458 IL - 0001-5458 PT - Journal Article PT - Randomized Controlled Trial ID - 17290690 [pubmed] PP - ppublish LG - English DP - 2006 Nov-Dec DC - 20070212 EZ - 2007/02/13 09:00 DA - 2007/03/21 09:00 DT - 2007/02/13 09:00 YR - 2006 ED - 20070320 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17290690 <529. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17200909 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Van Sickle KR AU - Gallagher AG AU - Smith CD FA - Van Sickle, K R FA - Gallagher, A G FA - Smith, C D IN - Van Sickle, K R. Department of Surgery, University of Texas Health Science Center San Antonio, 7703 Floyd Curl Drive, Mail Code 7842, San Antonio, TX 78229-3900, USA. Sickle@uthscsa.edu TI - The effect of escalating feedback on the acquisition of psychomotor skills for laparoscopy. SO - Surgical Endoscopy. 21(2):220-4, 2007 Feb AS - Surg Endosc. 21(2):220-4, 2007 Feb NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adult MH - Analysis of Variance MH - Clinical Competence MH - Computer Simulation MH - *Education, Medical, Undergraduate/mt [Methods] MH - Educational Technology/mt [Methods] MH - *Feedback, Psychological MH - Female MH - Humans MH - *Laparoscopy MH - Male MH - *Minimally Invasive Surgical Procedures/ed [Education] MH - Probability MH - Prospective Studies MH - *Psychomotor Performance/ph [Physiology] MH - Students, Medical MH - User-Computer Interface AB - BACKGROUND: In the acquisition of new skills that are difficult to master, such as those required for laparoscopy, feedback is a crucial component of the learning experience. Optimally, feedback should accurately reflect the task performance to be improved and be proximal to the training experience. In surgery, however, feedback typically is in vivo. The development of virtual reality training systems currently offers new training options. This study investigated the effect of feedback type and quality on laparoscopic skills acquisition. AB - METHODS: For this study, 32 laparoscopic novices were prospectively randomized into four training conditions, with 8 in each group. Group 1 (control) had no feedback. Group 2 (buzzer) had audio feedback when the edges were touched. Group 3 (voiced error) had an examiner voicing the word "error" each time the walls were touched. Group 4 (both) received both the audio buzzer and "error" voiced by the examiner All the subjects performed a maze-tracking task with a laparoscopic stylus inserted through a 5-mm port to simulate the fulcrum effect in minimally invasive surgery (MIS). A computer connected to the stylus scored an error each time the edge of the maze was touched, and the subjects were made aware of the error in the aforementioned manner. Ten 2-min trials were performed by the subjects while viewing a monitor. At the conclusion of training, all the subjects completed a 2-min trial of a simple laparoscopic cutting task, with the number of correct and incorrect incisions recorded. AB - RESULTS: Group 4 (both) made significantly more correct incisions than the other three groups (F = 12.13; df = 3, 28; p < 0.001), and also made significantly fewer errors or incorrect incisions (F = 14.4; p < 0.0001). Group 4 also made three times more correct incisions and 7.4 times fewer incorrect incisions than group 1 (control). AB - CONCLUSIONS: The type and quality of feedback during psychomotor skill acquisition for MIS have a large effect on the strength of skills generalization to a simple MIS task and should be given serious consideration in curriculum design for surgical training using simulation tasks. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-005-0847-5 PT - Journal Article PT - Randomized Controlled Trial ID - 17200909 [pubmed] ID - 10.1007/s00464-005-0847-5 [doi] PP - ppublish PH - 2005/12/05 [received] PH - 2006/04/27 [accepted] LG - English EP - 20070102 DP - 2007 Feb DC - 20070112 EZ - 2007/01/04 09:00 DA - 2007/02/08 09:00 DT - 2007/01/04 09:00 YR - 2007 ED - 20070207 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17200909 <530. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17108585 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Martens JD AU - van der Aa A AU - Panis B AU - van der Weijden T AU - Winkens RA AU - Severens JL FA - Martens, Jody D FA - van der Aa, Alied FA - Panis, Bert FA - van der Weijden, Trudy FA - Winkens, Ron A G FA - Severens, Johan L IN - Martens, Jody D. Integrated Care Unit, University Hospital Maastricht, The Netherlands. j.d.martens@caphri.unimaas.nl TI - Design and evaluation of a computer reminder system to improve prescribing behaviour of GPs. SO - Studies in Health Technology & Informatics. 124:617-23, 2006 AS - Stud Health Technol Inform. 124:617-23, 2006 NJ - Studies in health technology and informatics PI - Journal available in: Print PI - Citation processed from: Print JC - ck1, 9214582 IO - Stud Health Technol Inform SB - Health Technology Assessment Journals CP - Netherlands MH - *Drug Prescriptions MH - Humans MH - Netherlands MH - *Physicians, Family MH - *Practice Patterns, Physicians'/st [Standards] MH - *Reminder Systems AB - OBJECTIVE: To evaluate the implementation of a decision support system with reactive computer reminders to improve drug prescribing behaviour. AB - METHODS: A clustered RCT with an incomplete block design was carried out in the south of the Netherlands: 25 GPs received reminders on antibiotics and asthma/COPD prescriptions, 28 GPs received reminders on cholesterol prescriptions. Prescribing guidelines were integrated into the GP information system, which was installed in the GPs practices of the intervention group. When the computer program was in use, a reminder popped up if the GP deviated from the guidelines during prescribing. AB - PRIMARY OUTCOME: prescription according to the guidelines as a percentage of total prescriptions of a specific drug. Furthermore, an evaluation on the user-friendliness of the CRS in the GP's practice was carried out through questionnaires and interviews. AB - RESULTS: Presently analyses are being carried out. Preliminary results indicate that the CRS study supported our expectations. In general, there seems to be a reduction in the numbers of prescriptions according to the advices of the computerised guidelines not to prescribe certain drugs. Final analysis will be performed shortly. In general, the Computer Reminder System was perceived as stable and user friendly. AB - CONCLUSION: We created a stable and user friendly Computer Reminder System which was adjusted to the needs and demands of GPs. Preliminary results regarding the effectiveness of the system seem to indicate that the implementation of a Computer Reminder System with reactive reminders improves drug prescribing behaviour. IS - 0926-9630 IL - 0926-9630 PT - Evaluation Studies PT - Journal Article PT - Randomized Controlled Trial ID - 17108585 [pubmed] PP - ppublish LG - English DP - 2006 DC - 20061119 EZ - 2006/11/17 09:00 DA - 2007/01/20 09:00 DT - 2006/11/17 09:00 YR - 2006 ED - 20070119 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17108585 <531. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17169649 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Mikhail AA AU - Orvieto MA AU - Billatos ES AU - Zorn KC AU - Gong EM AU - Brendler CB AU - Zagaja GP AU - Shalhav AL FA - Mikhail, Albert A FA - Orvieto, Marcelo A FA - Billatos, Ehab S FA - Zorn, Kevin C FA - Gong, Edward M FA - Brendler, Charles B FA - Zagaja, Gregory P FA - Shalhav, Arieh L IN - Mikhail, Albert A. Department of Surgery, Section of Urology, University of Chicago Pritzker School of Medicine, Chicago, Illinois 60738, USA. almikhail@yahoo.com TI - Robotic-assisted laparoscopic prostatectomy: first 100 patients with one year of follow-up. SO - Urology. 68(6):1275-9, 2006 Dec AS - Urology. 68(6):1275-9, 2006 Dec NJ - Urology PI - Journal available in: Print PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotics MH - Time Factors MH - Treatment Outcome AB - OBJECTIVES: To report our initial experience of 100 patients with robotic-assisted laparoscopic radical prostatectomy. Continued technological advances have expanded our armamentarium of minimally invasive devices and techniques to offer our patients. Robotic-assisted laparoscopic radical prostatectomy has been adopted at many centers. AB - METHODS: This was a nonrandomized prospective study evaluating our initial 100 patients who underwent robotic-assisted laparoscopic radical prostatectomy. The follow-up data were obtained prospectively using the validated Rand 36-item health survey, version 2, and the University of California, Los Angeles, Prostate Cancer Index preoperatively and at 1, 3, 6, and 12 months postoperatively. Patients who required open conversion were excluded from the outcome analysis. Patients who received a sural nerve graft were excluded from the operative analysis. AB - RESULTS: The average age and body mass index of all patients were 58.4 years (range 42 to 70) and 28.5 kg/m2 (range 18.1 to 50.6), respectively, with a median follow-up of 12 months. The average prostate-specific antigen level was 6.07 ng/mL. Seven patients required conversion to an open technique, and four underwent sural nerve grafting. The positive surgical margin rate was 16% (15 of 92). Using the Rand 36-item health survey, version 2, and the University of California, Los Angeles, Prostate Cancer Index health surveys, the average percentage of return to baseline urinary function was 52%, 70%, 79%, and 84% at 1, 3, 6, and 12 months, respectively. The overall average percentage of return to baseline sexual function was 51%, 58%, 66%, and 80% at 1, 3, 6, and 12 months, respectively. AB - CONCLUSIONS: Robotic-assisted laparoscopic radical prostatectomy is a safe and efficient method for achieving prostate cancer control even during the initial learning curve for this procedure. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(06)01964-9 DO - https://dx.doi.org/10.1016/j.urology.2006.08.1060 PT - Clinical Trial PT - Journal Article ID - 17169649 [pubmed] ID - S0090-4295(06)01964-9 [pii] ID - 10.1016/j.urology.2006.08.1060 [doi] PP - ppublish PH - 2006/01/27 [received] PH - 2006/05/30 [revised] PH - 2006/08/11 [accepted] LG - English DP - 2006 Dec DC - 20061215 EZ - 2006/12/16 09:00 DA - 2007/01/16 09:00 DT - 2006/12/16 09:00 YR - 2006 ED - 20070112 RD - 20061215 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17169649 <532. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17070287 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Knudsen BE AU - Matsumoto ED AU - Chew BH AU - Johnson B AU - Margulis V AU - Cadeddu JA AU - Pearle MS AU - Pautler SE AU - Denstedt JD FA - Knudsen, Bodo E FA - Matsumoto, Edward D FA - Chew, Ben H FA - Johnson, Brooke FA - Margulis, Vitaly FA - Cadeddu, Jeffrey A FA - Pearle, Margaret S FA - Pautler, Stephen E FA - Denstedt, John D IN - Knudsen, Bodo E. Division of Urology, Ohio State University Medical Center, Columbus, Ohio 43210, USA. bodo.knudsen@osumc.edu TI - A randomized, controlled, prospective study validating the acquisition of percutaneous renal collecting system access skills using a computer based hybrid virtual reality surgical simulator: phase I. SO - Journal of Urology. 176(5):2173-8, 2006 Nov AS - J Urol. 176(5):2173-8, 2006 Nov NJ - The Journal of urology PI - Journal available in: Print PI - Citation processed from: Print JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - *Computer Simulation MH - *Computer-Assisted Instruction MH - Equipment Design MH - Humans MH - *Kidney Tubules, Collecting/su [Surgery] MH - Prospective Studies MH - *Urologic Surgical Procedures/ed [Education] MH - *User-Computer Interface AB - PURPOSE: The need to develop new methods of surgical training combined with advances in computing has led to the development of sophisticated virtual reality surgical simulators. The PERC Mentortrade mark is designed to train the user in percutaneous renal collecting system access puncture. We evaluated and established face, content and construct validation of the simulator in this task. AB - MATERIALS AND METHODS: A total of 63 trainees underwent baseline testing on the simulator, consisting of percutaneous renal puncture followed by the introduction of a guidewire into the collecting system. Subjects were then randomized to an intervention arm, in which they underwent 2, 30-minute training sessions on the simulator, and a control arm, in which no further training was given, followed by repeat testing. Performance was assessed using a global rating scale and by virtual reality derived parameters. AB - RESULTS: There were no significant differences between the 2 groups with respect to baseline measures. Subjects who underwent training with the simulator demonstrated significant improvement in objective and subjective parameters compared to their baseline performance and compared to the untrained control group. Spearman rank correlations demonstrated a significant relationship between multiple parameters of the objective and subjective data. AB - CONCLUSIONS: Training on the simulator improves virtual reality skills. It may allow trainees to develop the basic skills necessary to perform percutaneous renal collecting system access. Face and content validity were demonstrated and construct validity was supported by establishing convergent validity. IS - 0022-5347 IL - 0022-5347 DI - S0022-5347(06)01723-X DO - https://dx.doi.org/10.1016/j.juro.2006.07.011 PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Validation Studies ID - 17070287 [pubmed] ID - S0022-5347(06)01723-X [pii] ID - 10.1016/j.juro.2006.07.011 [doi] PP - ppublish PH - 2005/10/27 [received] LG - English DP - 2006 Nov DC - 20061030 EZ - 2006/10/31 09:00 DA - 2007/01/04 09:00 DT - 2006/10/31 09:00 YR - 2006 ED - 20070103 RD - 20061030 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17070287 <533. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 17058295 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Draaisma WA AU - Ruurda JP AU - Scheffer RC AU - Simmermacher RK AU - Gooszen HG AU - Rijnhart-de Jong HG AU - Buskens E AU - Broeders IA FA - Draaisma, W A FA - Ruurda, J P FA - Scheffer, R C H FA - Simmermacher, R K J FA - Gooszen, H G FA - Rijnhart-de Jong, H G FA - Buskens, E FA - Broeders, I A M J IN - Draaisma, W A. Department of Surgery, University Medical Centre Utrecht, Utrecht, The Netherlands. TI - Randomized clinical trial of standard laparoscopic versus robot-assisted laparoscopic Nissen fundoplication for gastro-oesophageal reflux disease. SO - British Journal of Surgery. 93(11):1351-9, 2006 Nov AS - Br J Surg. 93(11):1351-9, 2006 Nov NJ - The British journal of surgery PI - Journal available in: Print PI - Citation processed from: Print JC - b34, 0372553 IO - Br J Surg SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - Adult MH - Aged MH - Blood Loss, Surgical MH - Female MH - *Fundoplication/mt [Methods] MH - *Gastroesophageal Reflux/su [Surgery] MH - Humans MH - *Laparoscopy/mt [Methods] MH - Length of Stay MH - Male MH - Manometry MH - Middle Aged MH - Pain, Postoperative/et [Etiology] MH - Preoperative Care/mt [Methods] MH - Robotics MH - Treatment Outcome AB - BACKGROUND: Robotic systems for minimally invasive surgery may be of added value during extensive dissection and suturing in confined spaces, such as laparoscopic Nissen fundoplication (LNF). The purpose of this trial was to compare standard LNF with robot-assisted Nissen fundoplication (RNF). AB - METHODS: Between 2003 and 2005, 50 patients with confirmed refractory gastro-oesophageal reflux disease were assigned to LNF (25) or RNF (25). Patients who had undergone previous antireflux surgery were excluded. Independent assessment of dysphagia, regurgitation, heartburn and general well-being was performed before and 6 months after surgery using questionnaires. Objective outcome was studied 6 months after surgery by oesophageal manometry, 24-h pH monitoring, barium oesophagram series and upper endoscopy. AB - RESULTS: Operating time, blood loss, postoperative pain scores, hospital stay and complication rates did not differ significantly between the two groups. Reoperation rates were the same (one incisional hernia after LNF and one patient with repeat Nissen after RNF because of persistent dysphagia). Postoperative self-rated change in reflux symptoms and quality of life improved equally in both groups. The reduction in oesophageal acid exposure, increase in lower oesophageal sphincter tone and mucosal healing were comparable in both groups at follow-up. AB - CONCLUSION: RNF yielded similar subjective and objective results to LNF in this study. Therefore no additive value of robotic systems for this procedure was detected up to 6 months after surgery. IS - 0007-1323 IL - 0007-1323 DO - https://dx.doi.org/10.1002/bjs.5535 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 17058295 [pubmed] ID - 10.1002/bjs.5535 [doi] PP - ppublish LG - English DP - 2006 Nov DC - 20061030 EZ - 2006/10/24 09:00 DA - 2006/12/21 09:00 DT - 2006/10/24 09:00 YR - 2006 ED - 20061219 RD - 20061030 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17058295 <534. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15799920 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bonaros N AU - Schachner T AU - Oehlinger A AU - Jonetzko P AU - Mueller S AU - Moes N AU - Kolbitsch C AU - Mair P AU - Putz G AU - Laufer G AU - Bonatti J FA - Bonaros, Nikolaos FA - Schachner, Thomas FA - Oehlinger, Armin FA - Jonetzko, Patrycja FA - Mueller, Silvana FA - Moes, Nico FA - Kolbitsch, Christian FA - Mair, Peter FA - Putz, Guenther FA - Laufer, Guenther FA - Bonatti, Johannes IN - Bonaros, Nikolaos. Department of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria. TI - Experience on the way to totally endoscopic atrial septal defect repair. SO - Heart Surgery Forum. 7(5):E440-5, 2004 AS - Heart Surg Forum. 7(5):E440-5, 2004 NJ - The heart surgery forum PI - Journal available in: Print PI - Citation processed from: Internet JC - duc, 100891112 IO - Heart Surg Forum SB - Index Medicus CP - United States MH - Adult MH - *Endoscopy/mt [Methods] MH - Female MH - *Heart Septal Defects, Atrial/su [Surgery] MH - Humans MH - Male MH - Middle Aged MH - *Robotics/mt [Methods] MH - *Surgery, Computer-Assisted/mt [Methods] MH - Treatment Outcome MH - *Vascular Surgical Procedures/mt [Methods] AB - BACKGROUND: Remote-access perfusion and robotics have enabled totally endoscopic closure of atrial septal defect (ASD) and patent foramen ovale (PFO). We report on a stepwise approach to a totally endoscopic procedure. AB - METHODS: Seventeen patients (median age, 39 years; range, 21-55 years) underwent limited-access ASD or PFO closure. As a preparative step, the operation was carried out through minithoracotomy in 11 patients. In parallel, experience with robotic surgery was gained with totally endoscopic coronary artery bypass grafting procedures. After performance of ASD closures in dry-laboratory models using the da Vinci telemanipulation system, 6 patients were operated on in a totally endoscopic fashion. AB - RESULTS: With the endoscopic approach, significant learning curves were noted for cardiopulmonary bypass time y(min) = 226 - 41 * ln(x) (P = .03) and aortic cross-clamp time y(min) = 134 - 42 * ln(x) (P = .01) (x = number of procedures). There was no hospital mortality, and no residual shunts were detected at postoperative echocardiography. Median ventilation time was 9 hours (range, 0-18 hours) for the minithoracotomy group and 6 hours (range, 4-19 hours) for the totally endoscopic group. Median intensive care unit stay was 20 hours (range, 18-24 hours) and 18 hours (range, 18- 120 hours), respectively. AB - CONCLUSIONS: The implementation of robotic totally endoscopic closure of ASD or PFO in a heart surgery program seems to be safe. An intermediate step of performing the operations through minithoracotomy, adapting to remote access perfusion systems, and gaining experience in other robotic cardiac surgical procedures seems worthwhile. Learning curves are apparent, and adequate defect closure does not seem to be compromised by the totally endoscopic approach. ES - 1522-6662 IL - 1098-3511 DI - U5TDVM69N5A6X3YE DO - https://dx.doi.org/10.1532/HSF98.20041098 PT - Controlled Clinical Trial PT - Journal Article ID - 15799920 [pubmed] ID - U5TDVM69N5A6X3YE [pii] ID - 10.1532/HSF98.20041098 [doi] PP - ppublish LG - English DP - 2004 DC - 20050331 EZ - 2005/04/01 09:00 DA - 2006/12/14 09:00 DT - 2005/04/01 09:00 YR - 2004 ED - 20061213 RD - 20050331 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15799920 <535. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15769694 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Jansens JL AU - Ducart A AU - Preumont N AU - Jottrand M AU - Stefanidis C AU - Stoupel E AU - de Canniere D FA - Jansens, Jean Luc FA - Ducart, Anne FA - Preumont, Nicolas FA - Jottrand, Maurice FA - Stefanidis, Constantin FA - Stoupel, Eric FA - de Canniere, Didier IN - Jansens, Jean Luc. Department of Cardiac Surgery, Erasme University Hospital, Brussels, Belgium. jjansens@ulb.ac.be TI - Pulmonary vein isolation by robotic-enhanced thoracoscopy for symptomatic paroxysmal atrial fibrillation. SO - Heart Surgery Forum. 7(6):E595-8, 2004 AS - Heart Surg Forum. 7(6):E595-8, 2004 NJ - The heart surgery forum PI - Journal available in: Print PI - Citation processed from: Internet JC - duc, 100891112 IO - Heart Surg Forum SB - Index Medicus CP - United States MH - *Atrial Fibrillation/su [Surgery] MH - *Endoscopy/mt [Methods] MH - Feasibility Studies MH - Female MH - *Heart Conduction System/su [Surgery] MH - Humans MH - Male MH - Middle Aged MH - *Pulmonary Veins/su [Surgery] MH - *Robotics/mt [Methods] MH - *Surgery, Computer-Assisted/mt [Methods] MH - *Thoracic Surgical Procedures/mt [Methods] MH - Treatment Outcome AB - BACKGROUND: Pulmonary vein isolation (PVI) has been shown to be effective treatment of patients with symptomatic paroxysmal atrial fibrillation (PAF). The percutaneous approach is currently the technique of choice. Unfortunately, this procedure has limitations and complications that lead to fluctuating success rates. We explored an alternative technique of robotic-enhanced, closed-chest PVI with an endoscopic microwave-based catheter. AB - METHODS: Seven symptomatic PAF patients were included in the study. The pulmonary veins were isolated through right (only) robotic-enhanced thoracoscopy on the beating heart. AB - RESULTS: Six patients underwent successful endoscopic PVI. In 1 patient the operation was converted into small right thoracotomy. Operative assessment of the ablation line showed a successful electric block in every patient. Three months after the procedure, the first 5 patients were in permanent sinus rhythm. The 2 other patients had AF but had less frequent and less symptomatic episodes compared with the preoperative situation. AB - CONCLUSIONS: On the basis of this preliminary experience, we believe that in the near future endoscopic right-chest robotic-enhanced PVI on the beating heart may become a valid option in the treatment of symptomatic PAF patients. This procedure allows for more-reproducible ablation lines and may avoid many of the pitfalls and drawbacks of the percutaneous approach. Therefore this technique deserves larger prospective evaluation in the treatment of AF. ES - 1522-6662 IL - 1098-3511 DI - L6LNQDRE6319735V DO - https://dx.doi.org/10.1532/HSF98.20041107 PT - Clinical Trial PT - Journal Article ID - 15769694 [pubmed] ID - L6LNQDRE6319735V [pii] ID - 10.1532/HSF98.20041107 [doi] PP - ppublish LG - English DP - 2004 DC - 20050316 EZ - 2005/03/17 09:00 DA - 2006/12/14 09:00 DT - 2005/03/17 09:00 YR - 2004 ED - 20061213 RD - 20050316 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15769694 <536. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16736336 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Nakadi IE AU - Melot C AU - Closset J AU - DeMoor V AU - Betroune K AU - Feron P AU - Lingier P AU - Gelin M FA - Nakadi, Issam El FA - Melot, Christian FA - Closset, Jean FA - DeMoor, Veronique FA - Betroune, Kahina FA - Feron, Pascale FA - Lingier, Pierre FA - Gelin, Michel IN - Nakadi, Issam El. Department of Digestive Surgery, Erasme Hospital, 808 Route de Lennik-1070 Brussels, Belgium. ielnakad@ulb.ac.be TI - Evaluation of da Vinci Nissen fundoplication clinical results and cost minimization. SO - World Journal of Surgery. 30(6):1050-4, 2006 Jun AS - World J Surg. 30(6):1050-4, 2006 Jun NJ - World journal of surgery PI - Journal available in: Print PI - Citation processed from: Print JC - xo8, 7704052 IO - World J Surg SB - Index Medicus CP - United States MH - Adult MH - Belgium MH - Cost Savings MH - Costs and Cost Analysis MH - Feasibility Studies MH - Female MH - Fundoplication/ec [Economics] MH - *Fundoplication MH - Gastroesophageal Reflux/ec [Economics] MH - *Gastroesophageal Reflux/su [Surgery] MH - Humans MH - Laparoscopy/ec [Economics] MH - Length of Stay MH - Male MH - Middle Aged MH - Postoperative Complications MH - Robotics/ec [Economics] MH - *Robotics AB - BACKGROUND: A new technical tool was developed and introduced into the therapeutic field of videoscopic surgery-robotic telemanipulation surgery. The aim of this study is to investigate in a prospective randomized trial the feasibility of the Nissen procedure using the da Vinci and to evaluate the benefits and the costs of this new technique compared with the conventional laparoscopic approach. AB - MATERIALS AND METHODS: Twenty patients with gastro-esophageal reflux disease (GERD) were randomized into laparoscopic Nissen versus robot-assisted Nissen fundoplication. All the patients signed an informed consent document. The time data of the procedure, the efficacy of the instruments, the intra-operative incidents, postoperative morbidity, and cost minimization are presented. AB - RESULTS: Nine patients were assigned to the robot, and 11 to the laparoscopic procedure. Both groups were similar in age, male/female ratio, and body mass index. The robot procedure time was significantly longer. The hospital stay and the alimentation day were similar. The number of postoperative complaints was similar after the 1st, 6th, and 12th postoperative months. However, on the 3rd postoperative month, the number of complaints was significantly higher in the robot group. The robot procedure was more expensive with regard to the instrumentation and reusable material, the nursing costs, the investment costs, and the maintenance costs. AB - CONCLUSIONS: No clear advantage of using robotics in the Nissen procedure was observed. The procedure seems to be feasible and safe. The technique is limited because of unadapted instruments. The disadvantages are the high costs and prolonged operative time. IS - 0364-2313 IL - 0364-2313 DO - https://dx.doi.org/10.1007/s00268-005-7950-6 PT - Journal Article PT - Randomized Controlled Trial ID - 16736336 [pubmed] ID - 10.1007/s00268-005-7950-6 [doi] PP - ppublish LG - English DP - 2006 Jun DC - 20060531 EZ - 2006/06/01 09:00 DA - 2006/12/09 09:00 DT - 2006/06/01 09:00 YR - 2006 ED - 20061205 RD - 20060531 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16736336 <537. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16771713 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sim HG AU - Yip SK AU - Lau WK AU - Tan YH AU - Wong MY AU - Cheng CW FA - Sim, Hong Gee FA - Yip, Sidney Kam Hung FA - Lau, Weber Kam On FA - Tan, Yeh Hong FA - Wong, Michael Yuet Chen FA - Cheng, Christopher Wai Sam IN - Sim, Hong Gee. Singapore General Hospital, Department of Urology, Singapore. TI - Team-based approach reduces learning curve in robot-assisted laparoscopic radical prostatectomy. SO - International Journal of Urology. 13(5):560-4, 2006 May AS - Int J Urol. 13(5):560-4, 2006 May NJ - International journal of urology : official journal of the Japanese Urological Association PI - Journal available in: Print PI - Citation processed from: Print JC - ce6, 9440237 IO - Int. J. Urol. SB - Index Medicus CP - Australia MH - Follow-Up Studies MH - *Group Processes MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy MH - Male MH - Middle Aged MH - *Professional Competence MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/ed [Education] MH - Prostatic Diseases/pa [Pathology] MH - *Prostatic Diseases/su [Surgery] MH - *Robotics/ed [Education] MH - Robotics/td [Trends] MH - Treatment Outcome AB - AIM: We assessed the team approach in reducing the learning curve during our 2-year experience transiting from open to robot-assisted laparoscopic radical prostatectomy (rLRP). AB - METHODS: A team of three urologists progressed through assistant phase to console phase to obtain competency in robotic prostatectomy. One hundred patients underwent rLRP by this team using the da Vinci robotic surgical system from 1 February 2003 to 15 May 2005. AB - RESULTS: The immediate perioperative outcome was divided into three corresponding time frames and the results demonstrated gradual improvement in outcome parameters. The mean set-up time and dissection time were 24+/-14 min and 182+/-52 min, respectively. The mean perioperative blood loss was 272+/-240 mL, and 7% of patients (n=7) required blood transfusion. The mean duration of bladder catheterization was 8.4+/-4.1 days, and mean hospital stay was 2.9+/-1.6 days. There was no perioperative mortality or conversion to open radical prostatectomy. Major complications (4%) included urethrovesical leak requiring re-operation, postoperative cerebrovascular accident, and transient ureteric obstruction. Minor complications (7%) included minor urethrovesical leak, bladder neck stenosis, and urinary tract infection. Mean follow up was 6.6+/-5.0 months. Pathological assessment showed pT2 disease in 55% and pT3 in 45% of specimens. AB - CONCLUSIONS: A team-based approach to robot-assisted LRP helped to reduce the learning curve of the procedure for individual surgeons and continued to show significantly lower perioperative blood loss, transfusion requirements and postoperative pain compared to open radical retropubic prostatectomy. IS - 0919-8172 IL - 0919-8172 DI - IJU DO - https://dx.doi.org/10.1111/j.1442-2042.2006.01354.x PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 16771713 [pubmed] ID - IJU [pii] ID - 10.1111/j.1442-2042.2006.01354.x [doi] PP - ppublish LG - English DP - 2006 May DC - 20060614 EZ - 2006/06/15 09:00 DA - 2006/12/09 09:00 DT - 2006/06/15 09:00 YR - 2006 ED - 20061130 RD - 20060614 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16771713 <538. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16925289 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sanchez BR AU - Mohr CJ AU - Morton JM AU - Safadi BY AU - Alami RS AU - Curet MJ FA - Sanchez, Barry R FA - Mohr, Catherine J FA - Morton, John M FA - Safadi, Bassem Y FA - Alami, Ramzi S FA - Curet, Myriam J IN - Sanchez, Barry R. Department of Surgery, Stanford University Medical Center, Stanford, California 94305, USA. TI - Comparison of totally robotic laparoscopic Roux-en-Y gastric bypass and traditional laparoscopic Roux-en-Y gastric bypass. SO - Surgery for Obesity & Related Diseases. 1(6):549-54, 2005 Nov-Dec AS - Surg. obes. relat. dis.. 1(6):549-54, 2005 Nov-Dec NJ - Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery PI - Journal available in: Print PI - Citation processed from: Print JC - 101233161 IO - Surg Obes Relat Dis SB - Index Medicus CP - United States MH - Adult MH - Anastomosis, Roux-en-Y MH - Clinical Competence MH - Female MH - Gastric Bypass/ed [Education] MH - *Gastric Bypass/mt [Methods] MH - Humans MH - *Laparoscopy/mt [Methods] MH - Length of Stay MH - Male MH - Middle Aged MH - Obesity, Morbid/su [Surgery] MH - Robotics/ec [Economics] MH - Robotics/ed [Education] MH - *Robotics MH - Treatment Outcome AB - BACKGROUND: Laparoscopic gastric bypass is a technically demanding operation, especially when hand-sewing is required. Robotics may help facilitate the performance of this difficult operation. This study was undertaken to compare a single surgeon's results using the daVinci Surgical System with those using traditional laparoscopic Roux-en-Y gastric bypass (LRYGB) when the techniques were learned simultaneously. AB - METHODS: From July 2004 to April 2005, the new laparoscopic fellow's first 50 patients were randomized to undergo either LRYGB or totally robotic laparoscopic Roux-en-Y gastric bypass (TRRYGB). Data were collected on patient age, gender, body mass index (BMI), co-morbidities, operative time, complication rates, and length of stay. Student's t test with unequal variances was used for statistical analysis. AB - RESULTS: No significant differences in age, gender, co-morbidities, complication rates, or length of stay were found between the two groups. The mean operating time was significantly shorter for TRRYGB than for LRYGB (130.8 versus 149.4 minutes; P = 0.02), with a significant difference in minutes per BMI (2.94 versus 3.47 min/BMI; P = 0.02). The largest difference was in patients with a BMI >43 kg/m(2), for whom the difference in procedure time was 29.6 minutes (123.5 minutes for TRRYGB versus 153.2 minutes for LRYGB; P = 0.009) and a significant difference in minutes per BMI (2.49 versus 3.24 min/BMI; P = 0.009). AB - CONCLUSION: Our data indicate that the use of the daVinci Surgical System for TRRYGB is safe and feasible. The operating room time is shorter with the use of the robotic system during a surgeon's learning curve, and that decrease is maximized in patients with a larger BMI. TRRYGB may be a better approach to gastric bypass when hand-sewing is required, especially early in a surgeon's experience. IS - 1550-7289 IL - 1550-7289 DI - S1550-7289(05)00739-2 DO - https://dx.doi.org/10.1016/j.soard.2005.08.008 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 16925289 [pubmed] ID - S1550-7289(05)00739-2 [pii] ID - 10.1016/j.soard.2005.08.008 [doi] PP - ppublish PH - 2005/06/08 [received] PH - 2005/08/26 [revised] PH - 2005/08/26 [accepted] LG - English DP - 2005 Nov-Dec DC - 20060823 EZ - 2006/08/24 09:00 DA - 2006/09/29 09:00 DT - 2006/08/24 09:00 YR - 2005 ED - 20060928 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16925289 <539. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16181841 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bodner JC AU - Zitt M AU - Ott H AU - Wetscher GJ AU - Wykypiel H AU - Lucciarini P AU - Schmid T FA - Bodner, Johannes C FA - Zitt, Matthias FA - Ott, Harald FA - Wetscher, Gerold J FA - Wykypiel, Heinz FA - Lucciarini, Paolo FA - Schmid, Thomas IN - Bodner, Johannes C. Department of General and Transplant Surgery, Innsbruck Medical University, Innsbruck, Austria. TI - Robotic-assisted thoracoscopic surgery (RATS) for benign and malignant esophageal tumors. SO - Annals of Thoracic Surgery. 80(4):1202-6, 2005 Oct AS - Ann Thorac Surg. 80(4):1202-6, 2005 Oct NJ - The Annals of thoracic surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 15030100R IO - Ann. Thorac. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - Netherlands MH - Adenocarcinoma/su [Surgery] MH - Aged MH - Carcinoma, Squamous Cell/su [Surgery] MH - Esophageal Cyst/su [Surgery] MH - *Esophageal Neoplasms/su [Surgery] MH - Female MH - Follow-Up Studies MH - Humans MH - Leiomyoma/su [Surgery] MH - Length of Stay MH - Male MH - Middle Aged MH - Neoplasm Recurrence, Local MH - Robotics/is [Instrumentation] MH - Robotics/mt [Methods] MH - *Thoracoscopy/mt [Methods] MH - Treatment Outcome AB - BACKGROUND: Robotic surgical systems are most effective for operations in areas that are small and difficult to reach. Ideal indications for this new technology have yet to be established. The esophagus possesses attributes that are interesting for general thoracic robotic surgeons. AB - METHODS: Robotic-assisted thoracoscopic surgery (RATS) using the da Vinci system (Intuitive Surgical, Inc, Mountain View, CA) was performed in six patients with esophageal tumors. This comprised the dissection of the intrathoracic esophagus including lymph node dissection in four patients suffering from esophageal cancer and the extirpation of a benign lesion (one leiomyoma and one foregut cyst) in the remaining two patients. AB - RESULTS: All procedures were completed successfully with the robot. The median overall operating time was 173 (160-190) minutes in the oncologic cases and 121 minutes in the benign cases, including the robotic act of 147 (135-160) minutes and 94 minutes, respectively. There were no intraoperative complications. One patient had to undergo a redo thoracoscopy because of a persistent lymph fistula. One cancer patient died after 12 months due to tumor progression and another patient had to be stented due to local tumor recurrence 19 months postoperatively. AB - CONCLUSIONS: This first small series of various esophageal pathologies treated by robotic-assisted thoracoscopic surgery supports the impression that the esophagus is an ideal organ for a robotic approach. The potential of the da Vinci system, especially for oncologic indications, remains to be proven in future clinical trials. ES - 1552-6259 IL - 0003-4975 DI - S0003-4975(05)00521-7 DO - https://dx.doi.org/10.1016/j.athoracsur.2005.03.061 PT - Clinical Trial PT - Journal Article ID - 16181841 [pubmed] ID - S0003-4975(05)00521-7 [pii] ID - 10.1016/j.athoracsur.2005.03.061 [doi] PP - ppublish PH - 2004/11/19 [received] PH - 2005/03/09 [revised] PH - 2005/03/16 [accepted] LG - English DP - 2005 Oct DC - 20050926 EZ - 2005/09/27 09:00 DA - 2006/09/20 09:00 DT - 2005/09/27 09:00 YR - 2005 ED - 20060919 RD - 20050926 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16181841 <540. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16280831 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Richman MB AU - Forman EH AU - Bayazit Y AU - Einstein DB AU - Resnick MI AU - Stovsky MD FA - Richman, Martin B FA - Forman, Ernest H FA - Bayazit, Yildirim FA - Einstein, Douglas B FA - Resnick, Martin I FA - Stovsky, Mark D IN - Richman, Martin B. Department of Urology, Case School of Medicine, University Hospitals of Cleveland, 1100 Euclid Avenue, Cleveland, OH 44106, USA. TI - A novel computer based expert decision making model for prostate cancer disease management. CM - Comment in: J Urol. 2006 May;175(5):1961-2; author reply 1962; PMID: 16600807 SO - Journal of Urology. 174(6):2310-8, 2005 Dec AS - J Urol. 174(6):2310-8, 2005 Dec NJ - The Journal of urology PI - Journal available in: Print PI - Citation processed from: Print JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Brachytherapy MH - Choice Behavior MH - *Decision Making, Computer-Assisted MH - Decision Support Techniques MH - Disease Management MH - Erectile Dysfunction/pp [Physiopathology] MH - Erectile Dysfunction/th [Therapy] MH - Evidence-Based Medicine MH - Humans MH - Male MH - Patient Participation MH - Physician-Patient Relations MH - Prostatectomy MH - Prostatic Neoplasms/pp [Physiopathology] MH - *Prostatic Neoplasms/th [Therapy] MH - Quality of Life MH - Sensitivity and Specificity AB - PURPOSE: We propose a strategic, computer based, prostate cancer decision making model based on the analytic hierarchy process. We developed a model that improves physician-patient joint decision making and enhances the treatment selection process by making this critical decision rational and evidence based. AB - MATERIALS AND METHODS: Two groups (patient and physician-expert) completed a clinical study comparing an initial disease management choice with the highest ranked option generated by the computer model. Participants made pairwise comparisons to derive priorities for the objectives and subobjectives related to the disease management decision. The weighted comparisons were then applied to treatment options to yield prioritized rank lists that reflect the likelihood that a given alternative will achieve the participant treatment goal. Aggregate data were evaluated by inconsistency ratio analysis and sensitivity analysis, which assessed the influence of individual objectives and subobjectives on the final rank list of treatment options. AB - RESULTS: Inconsistency ratios less than 0.05 were reliably generated, indicating that judgments made within the model were mathematically rational. The aggregate prioritized list of treatment options was tabulated for the patient and physician groups with similar outcomes for the 2 groups. Analysis of the major defining objectives in the treatment selection decision demonstrated the same rank order for the patient and physician groups with cure, survival and quality of life being more important than controlling cancer, preventing major complications of treatment, preventing blood transfusion complications and limiting treatment cost. Analysis of subobjectives, including quality of life and sexual dysfunction, produced similar priority rankings for the patient and physician groups. Concordance between initial treatment choice and the highest weighted model option differed between the groups with the patient group having 59% concordance and the physician group having only 42% concordance. AB - CONCLUSIONS: This study successfully validated the usefulness of a computer based prostate cancer management decision making model to produce individualized, rational, clinically appropriate disease management decisions without physician bias. IS - 0022-5347 IL - 0022-5347 DI - S0022-5347(01)69013-X DO - https://dx.doi.org/10.1097/01.ju.0000181829.07078.22 PT - Clinical Trial PT - Journal Article PT - Validation Studies ID - 16280831 [pubmed] ID - S0022-5347(01)69013-X [pii] ID - 10.1097/01.ju.0000181829.07078.22 [doi] PP - ppublish LG - English DP - 2005 Dec DC - 20051110 EZ - 2005/11/11 09:00 DA - 2006/09/16 09:00 DT - 2005/11/11 09:00 YR - 2005 ED - 20060915 RD - 20071115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16280831 <541. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16928484 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Turner WF Jr AU - Sloan JH FA - Turner, William F Jr FA - Sloan, John H IN - Turner, William F Jr. Center for Advanced Surgery and Technology, Trinity Mother Frances Health System, Tyler, Texas 75701, USA. wftjrtyler@aol.com TI - Robotic-assisted coronary artery bypass on a beating heart: initial experience and implications for the future. SO - Annals of Thoracic Surgery. 82(3):790-4; discussion 794, 2006 Sep AS - Ann Thorac Surg. 82(3):790-4; discussion 794, 2006 Sep NJ - The Annals of thoracic surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 15030100R IO - Ann. Thorac. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - Netherlands MH - Aged MH - Atrial Fibrillation/ep [Epidemiology] MH - Atrial Fibrillation/et [Etiology] MH - Comorbidity MH - *Coronary Artery Bypass, Off-Pump/is [Instrumentation] MH - Coronary Artery Bypass, Off-Pump/mt [Methods] MH - Female MH - Forecasting MH - Humans MH - Incidence MH - Infection/ep [Epidemiology] MH - Infection/et [Etiology] MH - Length of Stay/sn [Statistics & Numerical Data] MH - Male MH - Middle Aged MH - Pleural Effusion/ep [Epidemiology] MH - Pleural Effusion/et [Etiology] MH - Postoperative Complications/ep [Epidemiology] MH - Postoperative Hemorrhage/ep [Epidemiology] MH - Postoperative Hemorrhage/et [Etiology] MH - Postoperative Hemorrhage/su [Surgery] MH - Retrospective Studies MH - *Robotics MH - Treatment Outcome AB - BACKGROUND: Although totally endoscopic coronary artery bypass using facilitated anastomotic devices is still in development, practical less invasive surgical strategies using sophisticated robotic microsurgical systems have been applied to facilitate the journey to a completely endoscopic procedure. This report summarizes the initial clinical experience with off-pump coronary artery bypass grafting using the Intuitive da Vinci Surgical Robotic System. AB - METHODS: Robotically-assisted coronary artery bypass grafting through a small thoracotomy on a beating heart without the use of cardiopulmonary bypass was performed on 70 patients from February 16, 2004 through September 20, 2005. Postoperative morbidity, mortality, and length of stay were recorded. AB - RESULTS: Operative mortality was 0%. The average operative time per case for the entire series was 4 hours, 3 minutes. The average operative time per case for the first 10 cases was 5 hours, 56 minutes, which decreased to 3 hours, 52 minutes for the last 10 cases of the series. The incidents of postoperative complications were as follows: reoperations for bleeding (2 patients; 2.8%); transfusions (7 patients; 10%); atrial fibrillations (6 patients; 8.5%); infections (2 patients; 2.8%); neurologic (0%); renal failure (0%); and ventilation greater than 1 day (0%). The average postoperative length of stay was 5.7 days. AB - CONCLUSIONS: Early results suggest robotic-assisted coronary artery bypass grafting is a safe and effective means of myocardial revascularization and its continued clinical use is justified. Operative time has decreased with experience. Robotic-assisted coronary artery bypass grafting performed through a small thoracotomy on a beating heart without the use of cardiopulmonary bypass may pave the way to a completely endoscopic, closed chest procedure for coronary artery bypass grafting. ES - 1552-6259 IL - 0003-4975 DI - S0003-4975(06)00694-1 DO - https://dx.doi.org/10.1016/j.athoracsur.2006.03.112 PT - Clinical Trial PT - Journal Article ID - 16928484 [pubmed] ID - S0003-4975(06)00694-1 [pii] ID - 10.1016/j.athoracsur.2006.03.112 [doi] PP - ppublish PH - 2005/11/11 [received] PH - 2006/03/23 [revised] PH - 2006/03/28 [accepted] LG - English DP - 2006 Sep DC - 20060824 EZ - 2006/08/25 09:00 DA - 2006/09/14 09:00 DT - 2006/08/25 09:00 YR - 2006 ED - 20060913 RD - 20060824 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16928484 <542. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16885755 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - O'Malley BW Jr AU - Weinstein GS AU - Snyder W AU - Hockstein NG FA - O'Malley, Bert W Jr FA - Weinstein, Gregory S FA - Snyder, Wendy FA - Hockstein, Neil G IN - O'Malley, Bert W Jr. Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. bert.omalley@uphs.upenn.edu TI - Transoral robotic surgery (TORS) for base of tongue neoplasms. SO - Laryngoscope. 116(8):1465-72, 2006 Aug AS - Laryngoscope. 116(8):1465-72, 2006 Aug NJ - The Laryngoscope PI - Journal available in: Print PI - Citation processed from: Print JC - 8607378, l1w IO - Laryngoscope SB - Index Medicus CP - United States MH - Animals MH - Cadaver MH - Dogs MH - Humans MH - Male MH - Middle Aged MH - Minimally Invasive Surgical Procedures/is [Instrumentation] MH - *Minimally Invasive Surgical Procedures/mt [Methods] MH - Prospective Studies MH - Robotics/is [Instrumentation] MH - *Robotics/mt [Methods] MH - *Tongue Neoplasms/su [Surgery] AB - OBJECTIVE: To develop a minimally invasive surgical technique for the treatment of base of tongue neoplasms using the optical and technical advantages of robotic surgical instrumentation. AB - STUDY DESIGN: Ten experimental procedures including tongue base exposure and dissections were performed on three cadavers and two mongrel dogs. Transoral robotic surgery (TORS) was then performed on three human patients with tongue base cancers in a prospective human trial. AB - METHODS: Using the da Vinci Surgical Robot (Intuitive Surgical, Inc., Sunnyvale, CA), we performed a total of 10 base of tongue resections on edentulous and dentate cadavers as well as live mongrel dogs. In the cadaver models, exposure was evaluated using three different retractors, the Dingman, Crowe Davis, and FK retractors. The three human patients underwent TORS surgery of their tongue base cancers under an institutional review board approved prospective clinical trial. The ability to identify and preserve or resect key anatomic structures such as the glossopharyngeal, hypoglossal, and lingual nerves as well as techniques for identifying the lingual artery and achieving hemostasis were developed. AB - RESULTS: The da Vinci Surgical Robot provided excellent visualization and enabled removal of the posterior one third to one half of the oral tongue in cadavers, dogs, and human patients. Among the three retractors evaluated, the FK retractor offered the greatest versatility and overall exposure for robotic instrument maneuverability. Complete resection to negative surgical margins with excellent hemostasis and no complications was achieved in the live patient surgeries. AB - CONCLUSIONS: TORS provided excellent three-dimensional visualization and instrument access that allowed successful surgical resections from cadaver models to human patients. TORS is a novel and minimally invasive approach to tongue neoplasms that has significant advantages over classic open surgery or endoscopic transoral laser surgery. IS - 0023-852X IL - 0023-852X DI - 00005537-200608000-00027 DO - https://dx.doi.org/10.1097/01.mlg.0000227184.90514.1a PT - Clinical Trial PT - Journal Article ID - 16885755 [pubmed] ID - 10.1097/01.mlg.0000227184.90514.1a [doi] ID - 00005537-200608000-00027 [pii] PP - ppublish LG - English DP - 2006 Aug DC - 20060803 EZ - 2006/08/04 09:00 DA - 2006/09/02 09:00 DT - 2006/08/04 09:00 YR - 2006 ED - 20060901 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16885755 <543. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15940076 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Benassi L AU - Marconi L AU - Benassi G AU - Accorsi F AU - Angeloni M AU - Besagni F FA - Benassi, L FA - Marconi, L FA - Benassi, G FA - Accorsi, F FA - Angeloni, M FA - Besagni, F IN - Benassi, L. Department of Gynecology, Obstetrics and Neonatology, University of Parma, Parma, Italy. luigi.benassi@unipr.it TI - Minilaparotomy vs laparotomy for uterine myomectomies: a randomized controlled trial. SO - Minerva Ginecologica. 57(2):159-63, 2005 Apr AS - Minerva Ginecol. 57(2):159-63, 2005 Apr NJ - Minerva ginecologica PI - Journal available in: Print PI - Citation processed from: Print JC - n66, 0400731 IO - Minerva Ginecol SB - Index Medicus CP - Italy MH - Adult MH - Female MH - Humans MH - *Laparotomy/mt [Methods] MH - Middle Aged MH - Minimally Invasive Surgical Procedures/mt [Methods] MH - Myoma/pa [Pathology] MH - *Myoma/su [Surgery] MH - Uterine Neoplasms/pa [Pathology] MH - *Uterine Neoplasms/su [Surgery] AB - AIM: To evaluate the efficacy and applicability of the minilaparotomy technique in abdominal myomectomies and to compare it with traditional laparotomy. AB - METHODS: We enrolled 99 women, suffering from symptomatic uterine myomas, to be operated for myomectomy. Through computer randomization, 55 women were assigned to the study group (minilaparotomy) and 44 women to the control group (traditional laparotomy). Women assigned to the study group were operated using a recently modified minilaparotomy technique. Statistical evaluation was performed through Mann-Whitney U test, chi2 test, Student's t-test. AB - RESULTS: Duration of surgery, time for spontaneous recanalization and days of postoperative hospital stay were significantly lower in the study group, as well as treatment satisfaction reported by the patients (p<0.05). Moreover, each minilaparotomy operation ended by saving 620 Euro. AB - CONCLUSIONS: Minilaparotomy seems to be a valid alternative to the removal of symptomatic uterine myomas. The objective and subjective advantages in operated patients, as well as the reduction in sanitary costs are underlined. IS - 0026-4784 IL - 0026-4784 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 15940076 [pubmed] PP - ppublish LG - English DP - 2005 Apr DC - 20050607 EZ - 2005/06/09 09:00 DA - 2006/08/25 09:00 DT - 2005/06/09 09:00 YR - 2005 ED - 20060824 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15940076 <544. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16603687 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tang BT AU - Cheng CP AU - Draney MT AU - Wilson NM AU - Tsao PS AU - Herfkens RJ AU - Taylor CA FA - Tang, Beverly T FA - Cheng, Christopher P FA - Draney, Mary T FA - Wilson, Nathan M FA - Tsao, Philip S FA - Herfkens, Robert J FA - Taylor, Charles A IN - Tang, Beverly T. Department of Mechanical Engineering, Stanford University, Stanford, CA 94305-5431, USA. TI - Abdominal aortic hemodynamics in young healthy adults at rest and during lower limb exercise: quantification using image-based computer modeling. SO - American Journal of Physiology - Heart & Circulatory Physiology. 291(2):H668-76, 2006 Aug AS - Am J Physiol Heart Circ Physiol. 291(2):H668-76, 2006 Aug NJ - American journal of physiology. Heart and circulatory physiology PI - Journal available in: Print-Electronic PI - Citation processed from: Print JC - dkm, 100901228 IO - Am. J. Physiol. Heart Circ. Physiol. SB - Index Medicus CP - United States MH - Adult MH - Algorithms MH - *Aorta, Abdominal/ph [Physiology] MH - Computer Simulation MH - *Exercise/ph [Physiology] MH - Female MH - Heart/ph [Physiology] MH - *Hemodynamics/ph [Physiology] MH - Humans MH - Image Processing, Computer-Assisted MH - *Lower Extremity/ph [Physiology] MH - Magnetic Resonance Imaging MH - Male MH - Regional Blood Flow/ph [Physiology] MH - *Rest/ph [Physiology] MH - Rheology AB - Localization of atherosclerotic lesions in the abdominal aorta has been previously correlated to areas of adverse hemodynamic conditions, such as flow recirculation, low mean wall shear stress, and high temporal oscillations in shear. Along with its many systemic benefits, exercise is also proposed to have local benefits in the vasculature via the alteration of these regional flow patterns. In this work, subject-specific models of the human abdominal aorta were constructed from magnetic resonance angiograms of five young, healthy subjects, and computer simulations were performed under resting and exercise (50% increase in resting heart rate) pulsatile flow conditions. Velocity fields and spatial variations in mean wall shear stress (WSS) and oscillatory shear index (OSI) are presented. When averaged over all subjects, WSS increased from 4.8 +/- 0.6 to 31.6 +/- 5.7 dyn/cm2 and OSI decreased from 0.22 +/- 0.03 to 0.03 +/- 0.02 in the infrarenal aorta between rest and exercise. WSS significantly increased, whereas OSI decreased between rest and exercise at the supraceliac, infrarenal, and suprabifurcation levels, and significant differences in WSS were found between anterior and posterior sections. These results support the hypothesis that exercise provides localized benefits to the cardiovascular system through acute mechanical stimuli that trigger longer-term biological processes leading to protection against the development or progression of atherosclerosis. IS - 0363-6135 IL - 0363-6135 DI - 01301.2005 DO - https://dx.doi.org/10.1152/ajpheart.01301.2005 PT - Clinical Trial PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, Non-P.H.S. ID - 16603687 [pubmed] ID - 01301.2005 [pii] ID - 10.1152/ajpheart.01301.2005 [doi] PP - ppublish GI - No: P41RR09784 Organization: (RR) *NCRR NIH HHS* Country: United States LG - English EP - 20060407 DP - 2006 Aug DC - 20060714 EZ - 2006/04/11 09:00 DA - 2006/08/19 09:00 DT - 2006/04/11 09:00 YR - 2006 ED - 20060818 RD - 20071115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16603687 <545. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16844449 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Wagner AA AU - Varkarakis IM AU - Link RE AU - Sullivan W AU - Su LM FA - Wagner, Andrew A FA - Varkarakis, Ioannis M FA - Link, Richard E FA - Sullivan, Wendy FA - Su, Li-Ming IN - Wagner, Andrew A. James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA. awagne14@jhmi.edu TI - Comparison of surgical performance during laparoscopic radical prostatectomy of two robotic camera holders, EndoAssist and AESOP: a pilot study. SO - Urology. 68(1):70-4, 2006 Jul AS - Urology. 68(1):70-4, 2006 Jul NJ - Urology PI - Journal available in: Print PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Humans MH - *Laparoscopy MH - Male MH - Middle Aged MH - Pilot Projects MH - *Prostatectomy MH - *Robotics/is [Instrumentation] MH - *Video-Assisted Surgery/is [Instrumentation] AB - OBJECTIVES: Robotic camera holders provide steady camera movement and view during laparoscopic surgery. We compared two such robots, EndoAssist and AESOP, by evaluating timed setup and surgical performance during laparoscopic radical prostatectomy (LRP). AB - METHODS: We prospectively collected data for 20 patients undergoing LRP using either the EndoAssist or AESOP. AESOP was mounted to the surgical bed and controlled by an experienced assistant using a hand-held remote control. The EndoAssist device was placed over the patient's right shoulder. Its movements were executed by the surgeon using a head-mounted optical emitter with brief head movements detected by a sensor mounted atop the surgeon's video monitor. The robot setup time and LRP operative steps were timed and compared between the two cohorts. AB - RESULTS: The time for robot setup favored AESOP over the EndoAssist (2.0 minutes versus 5.3 minutes, P = 0.001). The time for accomplishing vas deferens and seminal vesicle dissection favored the EndoAssist (23 minutes versus 33 minutes, P = 0.04). However, no statistically significant difference was found in the efficiency of task performance between the two robots in any of the other 11 steps measured. AB - CONCLUSIONS: The EndoAssist appears to be equally efficient to the assistant-controlled AESOP robot with respect to surgical performance during LRP. The advantages of the EndoAssist include its accurate response and ability to provide the surgeon with complete control of the desired operative view without relying on an assistant. Its disadvantages include its large profile, lack of a table-mounted design, and the need for pedal activation. Additional modifications are needed to improve the efficiency and design of this novel robotic device further. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(06)00220-2 DO - https://dx.doi.org/10.1016/j.urology.2006.02.003 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 16844449 [pubmed] ID - S0090-4295(06)00220-2 [pii] ID - 10.1016/j.urology.2006.02.003 [doi] PP - ppublish PH - 2005/07/08 [received] PH - 2006/01/01 [revised] PH - 2006/02/01 [accepted] LG - English DP - 2006 Jul DC - 20060717 EZ - 2006/07/18 09:00 DA - 2006/08/17 09:00 DT - 2006/07/18 09:00 YR - 2006 ED - 20060816 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16844449 <546. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15942809 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ayav A AU - Bresler L AU - Hubert J AU - Brunaud L AU - Boissel P FA - Ayav, A FA - Bresler, L FA - Hubert, J FA - Brunaud, L FA - Boissel, P IN - Ayav, A. Department of Digestive Surgery, University Hospital of Nancy-Brabois, 54511 Vandoeuvre les Nancy, France. a.ayav@chu-nancy.fr TI - Robotic-assisted pelvic organ prolapse surgery. SO - Surgical Endoscopy. 19(9):1200-3, 2005 Sep AS - Surg Endosc. 19(9):1200-3, 2005 Sep NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adult MH - Aged MH - Feasibility Studies MH - Female MH - Humans MH - Middle Aged MH - Prospective Studies MH - *Rectal Prolapse/su [Surgery] MH - *Robotics MH - *Uterine Prolapse/su [Surgery] AB - BACKGROUND: This study describes technical aspect and short-term results of pelvic organ prolapse surgery using the da Vinci robotic system. AB - METHODS: During a 1-year period, 18 consecutive patients with pelvic organ prolapse were operated on using the da-Vinci system. Clinical data were prospectively collected and analyzed. AB - RESULTS: All but one procedure was successfully completed robotically (95%). Performed procedures were colpohysteropexy (n = 12), mesh rectopexy (n = 2), or sutured rectopexy combined with sigmoid resection (n = 4). Average setup time was 21 min and significantly decreased with experience. Mean operative time was 172 min (range, 45-280). There were no mortality and no specific morbidity due to the robotic approach. Mean hospital stay was 7 days. At 6 months, all patients were free of pelvic organ prolapse and stated that they were satisfied with anatomical and functional results. AB - CONCLUSION: Our experience indicates that using the da-Vinci robotic system is feasible, safe, and effective for the treatment of pelvic organ prolapse. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-004-2257-5 PT - Clinical Trial PT - Journal Article ID - 15942809 [pubmed] ID - 10.1007/s00464-004-2257-5 [doi] PP - ppublish PH - 2004/11/06 [received] PH - 2005/01/17 [accepted] LG - English EP - 20050512 DP - 2005 Sep DC - 20051026 EZ - 2005/06/09 09:00 DA - 2006/07/29 09:00 DT - 2005/06/09 09:00 YR - 2005 ED - 20060728 RD - 20051026 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15942809 <547. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16298920 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Anvari M AU - Broderick T AU - Stein H AU - Chapman T AU - Ghodoussi M AU - Birch DW AU - McKinley C AU - Trudeau P AU - Dutta S AU - Goldsmith CH FA - Anvari, Mehran FA - Broderick, Tim FA - Stein, Harvey FA - Chapman, Trevor FA - Ghodoussi, Moji FA - Birch, Daniel W FA - McKinley, Craig FA - Trudeau, Patrick FA - Dutta, Sanjeev FA - Goldsmith, Charles H IN - Anvari, Mehran. Centre for Minimal Access Surgery, St. Joseph's Healthcare, McMaster University, Hamilton, Ontario, Canada. anvari@mcmaster.ca TI - The impact of latency on surgical precision and task completion during robotic-assisted remote telepresence surgery. SO - Computer Aided Surgery. 10(2):93-9, 2005 Mar AS - Comput Aided Surg. 10(2):93-9, 2005 Mar NJ - Computer aided surgery : official journal of the International Society for Computer Aided Surgery PI - Journal available in: Print PI - Citation processed from: Print JC - cuk, 9708375 IO - Comput. Aided Surg. SB - Index Medicus CP - England MH - *Clinical Competence MH - Humans MH - Medical Errors/pc [Prevention & Control] MH - *Robotics MH - Sensitivity and Specificity MH - Single-Blind Method MH - *Surgery, Computer-Assisted/is [Instrumentation] MH - Surgery, Computer-Assisted/mt [Methods] MH - Task Performance and Analysis MH - *Telemedicine/is [Instrumentation] MH - Telemedicine/mt [Methods] MH - Time Factors AB - OBJECTIVE: It has been suggested that robotic-assisted remote telepresence surgery with a signal transmission latency of greater than 300 ms may not be possible. AB - METHODS: We evaluated the impact of four different latencies of up to 500 ms on task completion and error rate in five surgeons after completion of three different surgical tasks. AB - RESULTS: The surgeons were able to complete all tasks with a latency of 500 ms. However, higher latency was associated with higher error rates and task completion time (TCT). There were significant variations between surgeons and different tasks. AB - CONCLUSION: Surgeons are able to complete tasks with a signal transmission latency of up to 500 ms. The clinical impact of slower TCT and increased error rates encountered at higher latency needs to be established. IS - 1092-9088 IL - 1092-9088 DI - R552L38514471W77 DO - https://dx.doi.org/10.3109/10929080500228654 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 16298920 [pubmed] ID - R552L38514471W77 [pii] ID - 10.3109/10929080500228654 [doi] PP - ppublish LG - English DP - 2005 Mar DC - 20051121 EZ - 2005/11/22 09:00 DA - 2006/06/23 09:00 DT - 2005/11/22 09:00 YR - 2005 ED - 20060622 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16298920 <548. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16481296 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Zhou HX AU - Guo YH AU - Yu XF AU - Bao SY AU - Liu JL AU - Zhang Y AU - Ren YG FA - Zhou, Han-Xin FA - Guo, Yue-Hua FA - Yu, Xiao-Fang FA - Bao, Shi-Yun FA - Liu, Jia-Lin FA - Zhang, Yue FA - Ren, Yong-Gong IN - Zhou, Han-Xin. Department of Minimally Invasive Surgery, Shenzhen People's Hospital, Jinan University 2nd Clinical Medicine College, Shenzhen 518020, China. hxzhou55@yahoo.com.cn TI - Zeus robot-assisted laparoscopic cholecystectomy in comparison with conventional laparoscopic cholecystectomy. SO - Hepatobiliary & Pancreatic Diseases International. 5(1):115-8, 2006 Feb AS - Hepatobiliary Pancreat Dis Int. 5(1):115-8, 2006 Feb NJ - Hepatobiliary & pancreatic diseases international : HBPD INT PI - Journal available in: Print PI - Citation processed from: Print JC - 101151457 IO - HBPD INT SB - Index Medicus CP - Singapore MH - Adult MH - *Cholecystectomy, Laparoscopic/mt [Methods] MH - Equipment Design MH - Female MH - *Gallbladder Diseases/su [Surgery] MH - Humans MH - Male MH - Middle Aged MH - Retrospective Studies MH - *Robotics/is [Instrumentation] MH - Treatment Outcome AB - BACKGROUND: The robotic surgical system overcomes many technological obstacles of conventional laparoscopic surgery, and possesses enormous clinical applied potential. The aim of this study was to compare the efficacy of Zeus robot-assisted laparoscopic cholecystectomy with conventional laparoscopic cholecystectomy. AB - METHODS: Forty patients undergoing elective cholecystectomy were randomly divided into two groups. Patients in group A (n=20) underwent Zeus robot-assisted laparoscopic cholecystectomy, and patients in group B (n=20) received conventional laparoscopic cholecystectomy. The parameters on operative field, operative time, the number of actions, the rate of operative errors and minimal trauma were evaluated and compared between the two groups. AB - RESULTS: The number of clearing camera (1.1+/-1.0 times) and the time of adjusting the operative field (2.2+/-0.7 minutes) in group A were significantly less than those (4.5+/-1.5 times) and (7.5+/-1.2 minutes) in group B. The number of dissection actions (337+/-86 times) and the rate of operative errors (10%) in group A were less than those (389+/-94 times), (25%) in group B. The total operation time (104.9+/-20.5 minutes) and setup time (29.5+/-9.8 minutes) in group A were significantly longer than those (78.6+/-17.1 minutes), (12.6+/-2.5 minutes) in group B. Blood loss and postoperative hospitalization were similar. No postoperative complications occurred in both groups, and open cholecystectomy was performed in each group. AB - CONCLUSIONS: Zeus robot-assisted cholecystectomy inherits the benefits of minimally invasive surgery. The Zeus robotic surgical system is better than conventional laparoscopic technique in controlling the operative field and can be manipulated precisely and stably though it requires more operative time. IS - 1499-3872 DI - 796 PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 16481296 [pubmed] ID - 796 [pii] PP - ppublish LG - English DP - 2006 Feb DC - 20060216 EZ - 2006/02/17 09:00 DA - 2006/06/16 09:00 DT - 2006/02/17 09:00 YR - 2006 ED - 20060615 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16481296 <549. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16631654 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Argenziano M AU - Katz M AU - Bonatti J AU - Srivastava S AU - Murphy D AU - Poirier R AU - Loulmet D AU - Siwek L AU - Kreaden U AU - Ligon D AU - TECAB Trial Investigators FA - Argenziano, Michael FA - Katz, Marc FA - Bonatti, Johannes FA - Srivastava, Sudhir FA - Murphy, Douglas FA - Poirier, Robert FA - Loulmet, Didier FA - Siwek, Leland FA - Kreaden, Usha FA - Ligon, David FA - TECAB Trial Investigators IN - Argenziano, Michael. Milstein Hospital, Columbia University, New York, New York, USA. ma66@columbia.edu TI - Results of the prospective multicenter trial of robotically assisted totally endoscopic coronary artery bypass grafting. SO - Annals of Thoracic Surgery. 81(5):1666-74; discussion 1674-5, 2006 May AS - Ann Thorac Surg. 81(5):1666-74; discussion 1674-5, 2006 May NJ - The Annals of thoracic surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 15030100R IO - Ann. Thorac. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - Netherlands MH - Adult MH - Aged MH - Cardiopulmonary Bypass MH - Clinical Competence MH - Comorbidity MH - Coronary Artery Bypass/is [Instrumentation] MH - *Coronary Artery Bypass/mt [Methods] MH - Coronary Disease/ep [Epidemiology] MH - Coronary Disease/su [Surgery] MH - Endoscopy MH - Female MH - Humans MH - Male MH - Middle Aged MH - Prospective Studies MH - *Robotics AB - BACKGROUND: Robotic technology has been proven safe and efficacious in the performance of mitral valve repair and atrial septal defect repair. This report describes a Food and Drug Administration-sanctioned multicenter study of the safety and efficacy of the da Vinci system (Intuitive Surgical, Inc, Mountain View, CA) for totally endoscopic coronary artery bypass (TECAB) surgery. AB - METHODS: Patients requiring left anterior descending (LAD) coronary artery revascularization were eligible. The procedure was performed with femoro-femoral cardiopulmonary bypass (CPB), endoaortic balloon occlusion, and thoracoscopy. All aspects of the procedure were performed with the robotic system, from internal mammary artery harvest to coronary anastomosis. AB - RESULTS: Ninety-eight patients requiring single-vessel LAD revascularization were enrolled at 12 centers. Thirteen patients (13%) were excluded intraoperatively (eg, failed femoral cannulation, inadequate working space). In 85 patients (69 men, age 58 +/- 10 years) who underwent TECAB, CPB time was 117 +/- 44 minutes, cross-clamp time was 71 +/- 26 minutes, and hospital length of stay was 5.1 +/- 3.4 days. There were five (6%) conversions to open techniques. There were no deaths or strokes, one early reintervention, and one myocardial infarction (1.5%). Three-month angiography was performed in 76 patients, revealing significant anastomotic stenoses (> 50%) or occlusions in 6 patients. Overall freedom from reintervention or angiographic failure was 91%. AB - CONCLUSIONS: Robotic TECAB was accomplished with no mortality, low morbidity, and angiographic patency and reintervention rates comparable with published data. Although the use of CPB was a limitation of the technique, this experience represents a step toward more advanced procedures, such as multivessel or off-pump TECAB. ES - 1552-6259 IL - 0003-4975 DI - S0003-4975(05)01968-5 DO - https://dx.doi.org/10.1016/j.athoracsur.2005.11.007 PT - Clinical Trial PT - Journal Article PT - Multicenter Study ID - 16631654 [pubmed] ID - S0003-4975(05)01968-5 [pii] ID - 10.1016/j.athoracsur.2005.11.007 [doi] PP - ppublish PH - 2005/03/14 [received] PH - 2005/10/31 [revised] PH - 2005/11/03 [accepted] LG - English DP - 2006 May DC - 20060424 EZ - 2006/04/25 09:00 DA - 2006/05/26 09:00 DT - 2006/04/25 09:00 YR - 2006 ED - 20060525 RD - 20060424 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16631654 <550. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16552744 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Morino M AU - Pellegrino L AU - Giaccone C AU - Garrone C AU - Rebecchi F FA - Morino, M FA - Pellegrino, L FA - Giaccone, C FA - Garrone, C FA - Rebecchi, F IN - Morino, M. Department of Surgery, Minimally Invasive Surgery Centre, University of Turin, Corso Achille Mario Dogliotti 14, 10126 Turin, Italy. mario.morino@unito.it TI - Randomized clinical trial of robot-assisted versus laparoscopic Nissen fundoplication. SO - British Journal of Surgery. 93(5):553-8, 2006 May AS - Br J Surg. 93(5):553-8, 2006 May NJ - The British journal of surgery PI - Journal available in: Print PI - Citation processed from: Print JC - b34, 0372553 IO - Br J Surg SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - Adult MH - Aged MH - Female MH - Follow-Up Studies MH - *Fundoplication/mt [Methods] MH - *Gastroesophageal Reflux/su [Surgery] MH - Humans MH - Hydrogen-Ion Concentration MH - *Laparoscopy/mt [Methods] MH - Length of Stay MH - Male MH - Middle Aged MH - Quality of Life MH - *Robotics AB - BACKGROUND: Several studies have shown the safety and feasibility of robot-assisted antireflux surgery but comparative data are lacking. AB - METHODS: Fifty consecutive patients scheduled for laparoscopic antireflux surgery were randomized into two groups. Twenty-five patients underwent robot-assisted surgery and 25 standard laparoscopic fundoplication. All robot-assisted procedures were performed with the da Vinci Surgical System. AB - RESULTS: There were no significant differences in age, sex, body mass or preoperative reflux pattern between the groups. Operating times were significantly longer for robot-assisted than standard laparoscopic operations (mean total operating time 131.3 versus 91.1 min, P < 0.001; skin-to-skin time 78.0 versus 63.5 min, P = 0.001). There was no conversion to open surgery. Conversion to standard laparoscopy was necessary in one of 25 robot-assisted procedures. The length of hospital stay was similar in both groups. Robot-assisted surgery was associated with significantly higher mean total costs (euro 3157 versus euro 1527; P < 0.001). There were no significant differences in clinical, endoscopic and functional outcomes between groups. There was no procedure-related mortality. AB - CONCLUSION: Robot-assisted laparoscopic fundoplication is comparable to the standard laparoscopic procedure in terms of feasibility and outcome, but costs are higher owing to longer operating times and the use of more expensive instruments. IS - 0007-1323 IL - 0007-1323 DO - https://dx.doi.org/10.1002/bjs.5325 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 16552744 [pubmed] ID - 10.1002/bjs.5325 [doi] PP - ppublish LG - English DP - 2006 May DC - 20060417 EZ - 2006/03/23 09:00 DA - 2006/05/24 09:00 DT - 2006/03/23 09:00 YR - 2006 ED - 20060523 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16552744 <551. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15549629 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Corcione F AU - Esposito C AU - Cuccurullo D AU - Settembre A AU - Miranda N AU - Amato F AU - Pirozzi F AU - Caiazzo P FA - Corcione, F FA - Esposito, C FA - Cuccurullo, D FA - Settembre, A FA - Miranda, N FA - Amato, F FA - Pirozzi, F FA - Caiazzo, P IN - Corcione, F. Department of Surgery and Laparoscopy, AORN Monadi Hospital, Via Monaldi 234, Naples, 80100, Italy. TI - Advantages and limits of robot-assisted laparoscopic surgery: preliminary experience. SO - Surgical Endoscopy. 19(1):117-9, 2005 Jan AS - Surg Endosc. 19(1):117-9, 2005 Jan NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adult MH - Aged MH - Female MH - Humans MH - *Laparoscopy/mt [Methods] MH - Male MH - Middle Aged MH - *Robotics AB - BACKGROUND: In the last few years, robotics has been applied in clinical practice for a variety of laparoscopic procedures. This study reports our preliminary experience using robotics in the field of general surgery to evaluate the advantages and limitations of robot-assisted laparoscopy. AB - METHODS: Thirty-two consecutive patients were scheduled to undergo robot-assisted laparoscopic surgery in our units from March 2002 to July 2003. The indications were cholecystectomy, 20 patients; right adrenalectomy, two points; bilateral varicocelectomy, two points; Heller's cardiomyotomy, two points; Nissen's fundoplication, two points; total splenectomy, one point; right colectomy, one point; left colectomy, 1 point; and bilateral inguinal hernia repair, one point. In all cases, we used the da Vinci surgical system, with the surgeon at the robotic work station and an assistant by the operating table. AB - RESULTS: Twenty-nine of 32 procedures (90.6%) were completed robotically, whereas three were converted to laparoscopic surgery. Conversion to laparoscopy was due in two patients to minor bleeding that could not be managed robotically and to robot malfunction in the third patient. There were no deaths. Median hospital stay was 2.2 days (range, 2-8). AB - CONCLUSIONS: The main advantages of robot-assisted laparoscopic surgery are the availability of three-dimensional vision and easier instrument manipulation than can be obtain with standard laparoscopy. The learning curve to master the robot was >or= 10 robotic procedures. The main limitations are the large diameter of the instruments (8 mm) and the limited number of robotic arms (maximum, three). We consider these technical shortcomings to be the cause for our conversions, because it is difficult to manage bleeding episodes with only two operating instruments. The benefit to the patient must be evaluated carefully and proven before this technology can become widely accepted in general surgery. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-004-9004-9 PT - Clinical Trial PT - Journal Article ID - 15549629 [pubmed] ID - 10.1007/s00464-004-9004-9 [doi] PP - ppublish PH - 2004/01/12 [received] PH - 2004/04/22 [accepted] LG - English EP - 20041118 DP - 2005 Jan DC - 20050317 EZ - 2004/11/19 09:00 DA - 2006/04/28 09:00 DT - 2004/11/19 09:00 YR - 2005 ED - 20060426 RD - 20050317 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15549629 <552. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16469589 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Joseph JV AU - Rosenbaum R AU - Madeb R AU - Erturk E AU - Patel HR FA - Joseph, J V FA - Rosenbaum, R FA - Madeb, R FA - Erturk, E FA - Patel, H R H IN - Joseph, J V. Section of Laparoscopic and Robotic Surgery, Department of Urology, University of Rochester Medical Center, Rochester, New York 14642-8656, USA. jean-joseph@URMC.rochester.edu TI - Robotic extraperitoneal radical prostatectomy: an alternative approach. SO - Journal of Urology. 175(3 Pt 1):945-50; discussion 951, 2006 Mar AS - J Urol. 175(3 Pt 1):945-50; discussion 951, 2006 Mar NJ - The Journal of urology PI - Journal available in: Print PI - Citation processed from: Print JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Humans MH - *Laparoscopy MH - Middle Aged MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Robotics AB - PURPOSE: Laparoscopic radical prostatectomy with or without a robot has been increasingly performed worldwide, primarily using a transperitoneal approach. We report our experience with daVinci(R) robot assisted extraperitoneal laparoscopic radical prostatectomy. AB - MATERIALS AND METHODS: A total of 325 patients underwent robot assisted extraperitoneal laparoscopic radical prostatectomy for clinically localized prostate cancer at our center during a 2-year period. Perioperative data, and oncological and functional results were prospectively recorded. AB - RESULTS: Perioperative demographics included mean age, PSA and Gleason score, which were 60 years (range 42 to 76), 6.6 ng/ml (range 0.6 to 26) and 6 (range 5 to 9), respectively. Preoperative clinical stage was 81%, 16% and 3% for T1c, T2a and T2b, respectively. Average total operative time was 130 minutes (range 80 to 480). Intraoperative data included a mean blood loss of 196 cc with no open conversions. Bilateral, unilateral and nonnerve sparing prostatectomy was performed in 70%, 24% and 6% of patients, respectively. Of the patients 96% were discharged home within 8 to 23 hours of surgery. Pathological stage was pT2a, pT2b, pT3a and pT3b in 18%, 63%, 14% and 5% of all radical prostatectomy specimens, respectively, with an overall positive surgical margin rate of 13%. Two of 92 patients had positive nodal disease after lymph node dissection. Continence and erectile function were measured. AB - CONCLUSIONS: The extraperitoneal approach offers the advantages of improved dexterity and visualization of the robot, while avoiding the abdominal cavity and potential associated morbidity. As surgeons gain more experience with this new technology, the extraperitoneal approach simulating the standard open retropubic technique is likely to gain popularity. IS - 0022-5347 IL - 0022-5347 DI - S0022-5347(05)00340-X DO - https://dx.doi.org/10.1016/S0022-5347(05)00340-X PT - Clinical Trial PT - Journal Article ID - 16469589 [pubmed] ID - S0022-5347(05)00340-X [pii] ID - 10.1016/S0022-5347(05)00340-X [doi] PP - ppublish PH - 2005/05/02 [received] LG - English DP - 2006 Mar DC - 20060210 EZ - 2006/02/14 09:00 DA - 2006/03/31 09:00 DT - 2006/02/14 09:00 YR - 2006 ED - 20060330 RD - 20060210 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16469589 <553. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16283847 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Obek C AU - Hubka M AU - Porter M AU - Chang L AU - Porter JR FA - Obek, Can FA - Hubka, Michal FA - Porter, Michael FA - Chang, Lily FA - Porter, James R IN - Obek, Can. Department of Urology, University of Washington, Seattle, Washington, USA. canobek@yahoo.com TI - Robotic versus conventional laparoscopic skill acquisition: implications for training. SO - Journal of Endourology. 19(9):1098-103, 2005 Nov AS - J Endourol. 19(9):1098-103, 2005 Nov NJ - Journal of endourology PI - Journal available in: Print PI - Citation processed from: Print JC - brj, 8807503 IO - J. Endourol. SB - Index Medicus CP - United States MH - *Clinical Competence MH - Humans MH - *Laparoscopy/mt [Methods] MH - *Robotics/ed [Education] AB - BACKGROUND AND PURPOSE: Despite the growing interest in surgical robotics, very little study has been done regarding the acquisition of the skills needed to perform robotic surgery safely. The purpose of this study was to determine whether skills are transferred between conventional laparoscopy and robotically assisted surgery. AB - SUBJECTS AND METHODS: Intracorporeal knot tying was used for evaluating laparoscopic skills for time and error performance. Twenty medical students without any laparoscopic experience were randomized into two groups. Group A initially performed knot tying with conventional laparoscopic instruments, were trained with the daVinci Robotic System, and then performed knot tying with conventional laparoscopy. Group B performed knot tying with robotics, trained with standard laparoscopy, and completed post-training knot tying with robotics. Pretraining and post-training tasks were videotaped and analyzed using a detailed scoring system by one independent referee, who was blinded to the subjects' experience. AB - RESULTS: Pre-training knot tying was faster with robotics (4.4 v 9.9 minutes; P < 0.001). The mean composite scores were 27.4 for group A and 57.4 for group B (P = 0.09), and the error scores were 57.1 and 42.1 (P = 0.29), respectively. Post-training time for knot completion decreased to 6.7 minutes and 3.4 minutes for groups A and B, respectively. Composite scores increased significantly, from 27.4 to 66.1 for group A and 57.4 to 81.8 for group B. Error scores decreased to 32.9 for group A (P = 0.1) and 16.2 in group B (P = 0.02). AB - CONCLUSIONS: There appears to be reciprocal transfer of skills between conventional laparoscopy and robotically assisted surgery. However, this transference is incomplete. Our results suggest that training with either technique or conventional laparoscopy is superior to training with robotics alone. IS - 0892-7790 IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2005.19.1098 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 16283847 [pubmed] ID - 10.1089/end.2005.19.1098 [doi] PP - ppublish LG - English DP - 2005 Nov DC - 20051114 EZ - 2005/11/15 09:00 DA - 2006/03/31 09:00 DT - 2005/11/15 09:00 YR - 2005 ED - 20060330 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16283847 <554. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16445250 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lin DT AU - Lei CC AU - Hung SW FA - Lin, Daw-Tung FA - Lei, Chung-Chih FA - Hung, Siu-Wan IN - Lin, Daw-Tung. Department of Computer Science and Information Engineering, National Taipei University, Taiwan, ROC. dalton@mail.ntpu.edu.tw TI - Computer-aided kidney segmentation on abdominal CT images. SO - IEEE Transactions on Information Technology in Biomedicine. 10(1):59-65, 2006 Jan AS - IEEE Trans Inf Technol Biomed. 10(1):59-65, 2006 Jan NJ - IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society PI - Journal available in: Print PI - Citation processed from: Print JC - c8g, 9712259 IO - IEEE Trans Inf Technol Biomed SB - Index Medicus CP - United States MH - Algorithms MH - *Artificial Intelligence MH - Computer Simulation MH - Humans MH - Information Storage and Retrieval/mt [Methods] MH - *Kidney/dg [Diagnostic Imaging] MH - *Kidney Diseases/dg [Diagnostic Imaging] MH - Models, Biological MH - *Radiographic Image Enhancement/mt [Methods] MH - *Radiographic Image Interpretation, Computer-Assisted/mt [Methods] MH - *Radiography, Abdominal/mt [Methods] MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Subtraction Technique MH - *Tomography, X-Ray Computed/mt [Methods] AB - In this paper, an effective model-based approach for computer-aided kidney segmentation of abdominal CT images with anatomic structure consideration is presented. This automatic segmentation system is expected to assist physicians in both clinical diagnosis and educational training. The proposed method is a coarse to fine segmentation approach divided into two stages. First, the candidate kidney region is extracted according to the statistical geometric location of kidney within the abdomen. This approach is applicable to images of different sizes by using the relative distance of the kidney region to the spine. The second stage identifies the kidney by a series of image processing operations. The main elements of the proposed system are: 1) the location of the spine is used as the landmark for coordinate references; 2) elliptic candidate kidney region extraction with progressive positioning on the consecutive CT images; 3) novel directional model for a more reliable kidney region seed point identification; and 4) adaptive region growing controlled by the properties of image homogeneity. In addition, in order to provide different views for the physicians, we have implemented a visualization tool that will automatically show the renal contour through the method of second-order neighborhood edge detection. We considered segmentation of kidney regions from CT scans that contain pathologies in clinical practice. The results of a series of tests on 358 images from 30 patients indicate an average correlation coefficient of up to 88% between automatic and manual segmentation. IS - 1089-7771 IL - 1089-7771 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 16445250 [pubmed] PP - ppublish LG - English DP - 2006 Jan DC - 20060131 EZ - 2006/02/01 09:00 DA - 2006/03/01 09:00 DT - 2006/02/01 09:00 YR - 2006 ED - 20060228 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16445250 <555. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16159838 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Davidavicius G AU - Van Praet F AU - Mansour S AU - Casselman F AU - Bartunek J AU - Degrieck I AU - Wellens F AU - De Geest R AU - Vanermen H AU - Wijns W AU - De Bruyne B FA - Davidavicius, Giedrius FA - Van Praet, Frank FA - Mansour, Samer FA - Casselman, Filip FA - Bartunek, Jozef FA - Degrieck, Ivan FA - Wellens, Francis FA - De Geest, Raf FA - Vanermen, Hugo FA - Wijns, William FA - De Bruyne, Bernard IN - Davidavicius, Giedrius. Department of Cardiovascular and Thoracic Surgery, OLV Clinic, Aalst, Belgium. TI - Hybrid revascularization strategy: a pilot study on the association of robotically enhanced minimally invasive direct coronary artery bypass surgery and fractional-flow-reserve-guided percutaneous coronary intervention. SO - Circulation. 112(9 Suppl):I317-22, 2005 Aug 30 AS - Circulation. 112(9 Suppl):I317-22, 2005 Aug 30 NJ - Circulation PI - Journal available in: Print PI - Citation processed from: Internet JC - daw, 0147763 IO - Circulation SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Aged, 80 and over MH - *Angioplasty, Balloon, Coronary/mt [Methods] MH - Coronary Angiography MH - Coronary Disease/su [Surgery] MH - *Coronary Disease/th [Therapy] MH - Exercise Test MH - Female MH - Follow-Up Studies MH - Humans MH - Internal Mammary-Coronary Artery Anastomosis/is [Instrumentation] MH - *Internal Mammary-Coronary Artery Anastomosis/mt [Methods] MH - Male MH - Middle Aged MH - Minimally Invasive Surgical Procedures MH - Pilot Projects MH - Postoperative Complications/ep [Epidemiology] MH - *Robotics MH - Thoracotomy/mt [Methods] MH - Treatment Outcome AB - BACKGROUND: Robotically enhanced minimally invasive direct coronary artery bypass (RE-MIDCAB) graft of the left internal mammary artery to the left anterior descending coronary artery (LAD) and/or the first diagonal branch might be the least traumatic surgical revascularization approach available so far. When combined with fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) in the non-LAD vessels, this "hybrid" strategy takes advantage of the survival benefit conferred by the internal mammary artery graft to the LAD while providing the patients with a truly minimally invasive, functionally complete revascularization. AB - METHODS AND RESULTS: Twenty patients with multivessel disease were selected to undergo combined PCI and RE-MIDCAB because they had a lesion amenable to PCI in the right and/or the left circumflex coronary artery and a lesion in the LAD and/or the first diagonal branch that was considered less than ideal for PCI. PCI was actually performed only when FFR was <0.80 ("provisional PCI"). In 7 stenoses, FFR was >0.80 and the planned PCI was not performed. Surgery was performed before provisional PCI in 6 cases. An angiogram was obtained in all patients before discharge, and a complete clinical follow-up including a stress test was obtained in all patients after a mean of 12 months. There were no significant intraoperative complications, conversions to cardiopulmonary bypass, or reinterventions for bleeding. At early control angiogram, 2 moderate stenoses just proximal to anastomosis were observed, both with normal run-off. After 12 months there were no objective signs of ischemia at stress testing. After an average follow-up of 19+/-10 months there were no deaths, myocardial infarctions, or repeat revascularizations. AB - CONCLUSIONS: A hybrid strategy combining FFR-guided PCI and RE-MIDCAB seems safe and provides selected patients with a functionally complete revascularization with minimal surgical trauma and excellent clinical outcomes. ES - 1524-4539 IL - 0009-7322 DI - 112/9_suppl/I-317 DO - https://dx.doi.org/10.1161/CIRCULATIONAHA.104.524264 PT - Clinical Trial PT - Journal Article ID - 16159838 [pubmed] ID - 112/9_suppl/I-317 [pii] ID - 10.1161/CIRCULATIONAHA.104.524264 [doi] PP - ppublish LG - English DP - 2005 Aug 30 DC - 20050914 EZ - 2005/09/15 09:00 DA - 2006/02/24 09:00 DT - 2005/09/15 09:00 YR - 2005 ED - 20060221 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16159838 <556. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16269282 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Melvin WS AU - Dundon JM AU - Talamini M AU - Horgan S FA - Melvin, W Scott FA - Dundon, John M FA - Talamini, Mark FA - Horgan, Santiago IN - Melvin, W Scott. Division of General Surgery, Ohio State University, Columbus 43210, USA. Melvin.14@osu.edu TI - Computer-enhanced robotic telesurgery minimizes esophageal perforation during Heller myotomy. SO - Surgery. 138(4):553-8; discussion 558-9, 2005 Oct AS - Surgery. 138(4):553-8; discussion 558-9, 2005 Oct NJ - Surgery PI - Journal available in: Print PI - Citation processed from: Print JC - vc3, 0417347 IO - Surgery SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - *Digestive System Surgical Procedures/ae [Adverse Effects] MH - *Esophageal Achalasia/su [Surgery] MH - *Esophageal Perforation/pc [Prevention & Control] MH - Female MH - Follow-Up Studies MH - Humans MH - *Laparoscopy/ae [Adverse Effects] MH - Male MH - Middle Aged MH - *Robotics MH - *Surgery, Computer-Assisted MH - *Telemedicine/mt [Methods] MH - Treatment Outcome AB - BACKGROUND: Laparoscopic Heller myotomy has emerged as the treatment of choice for achalasia. However, intraoperative esophageal perforation remains a significant complication. Computer-enhanced operative techniques have the potential to improve outcomes for certain operative procedures. Robotic, computer-enhanced laparoscopic telemanipulators using 3-dimensional magnified imaging and motion scaling are designed uniquely to facilitate certain operations requiring fine-tissue manipulation. We hypothesized that computer-enhanced robotic Heller myotomy would reduce intraoperative complications compared with laparoscopic techniques. AB - METHODS: All patients undergoing an operation for achalasia at 3 institutions with a robotic surgery system (DaVinci; Intuitive Surgical Corporation, Sunnyvale, Calif) were followed-up prospectively. Demographics, perioperative course, complications, and hospital stay were recorded. Follow-up evaluation was obtained via a standardized symptom survey, office visits, and medical records. Data were compared with preoperative symptoms using a Mann-Whitney U test, and operating times were compared using the ANOVA test. AB - RESULTS: Between August 2000 and August 2004 there were 104 patients who underwent a robotic Heller myotomy with partial fundoplicaton. There were 53 women and 51 men. All patients were symptomatic. The operative time was 140.55 minutes overall, but improved from 162.63 minutes to 113.50 minutes from 2000-2002 to 2003-2004 (P = .0001). There were no esophageal perforations. There were 8 minor complications and 1 patient required conversion to an open operation. Sixty-six (62.3%) patients were discharged on the first postoperative day and the average hospital stay was 1.5 days. A symptom survey was completed in 79 of 104 patients (76%) at follow-up evaluation. Symptoms improved in all patients with an average follow-up symptom score of 0.48 compared with 5.0 before the operation (P = .0001). Forty-three of the 79 patients from whom follow-up data were collected had a minimum follow-up period of 1 year. The follow-up period averaged 16 months. No patients required reoperation. AB - CONCLUSIONS: Computer-enhanced robotic laparoscopic techniques provide a clear advantage over standard laparoscopy for the operative treatment of achalasia. We have shown in this large series that Heller myotomy can be completed using this technology without esophageal perforation. The application of computer-enhanced operative techniques appears to provide superior outcomes in selected procedures. IS - 0039-6060 IL - 0039-6060 DI - S0039-6060(05)00406-X DO - https://dx.doi.org/10.1016/j.surg.2005.07.025 PT - Clinical Trial PT - Journal Article ID - 16269282 [pubmed] ID - S0039-6060(05)00406-X [pii] ID - 10.1016/j.surg.2005.07.025 [doi] PP - ppublish PH - 2005/02/15 [received] PH - 2005/07/28 [revised] PH - 2005/07/30 [accepted] LG - English DP - 2005 Oct DC - 20051104 EZ - 2005/11/05 09:00 DA - 2005/12/13 09:00 DT - 2005/11/05 09:00 YR - 2005 ED - 20051129 RD - 20051104 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16269282 <557. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16146534 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Brevet M AU - Garidi R AU - Gruson B AU - Royer B AU - Vaida I AU - Damaj G FA - Brevet, M FA - Garidi, R FA - Gruson, B FA - Royer, B FA - Vaida, I FA - Damaj, G IN - Brevet, M. Centre Hospitalier Universitaire Amiens, Service des Maladies du Sang, Rue Laennec, 80054 Amiens Cedex 01, France. TI - First-line autologous stem cell transplantation in primary CNS lymphoma. SO - European Journal of Haematology. 75(4):288-92, 2005 Oct AS - Eur J Haematol. 75(4):288-92, 2005 Oct NJ - European journal of haematology PI - Journal available in: Print PI - Citation processed from: Print JC - erf, 8703985 IO - Eur. J. Haematol. SB - Index Medicus CP - England MH - Adult MH - Aged MH - Antineoplastic Combined Chemotherapy Protocols/tu [Therapeutic Use] MH - Antineoplastic Combined Chemotherapy Protocols/to [Toxicity] MH - Carmustine/tu [Therapeutic Use] MH - Central Nervous System Neoplasms/co [Complications] MH - Central Nervous System Neoplasms/mo [Mortality] MH - *Central Nervous System Neoplasms/th [Therapy] MH - Combined Modality Therapy/ae [Adverse Effects] MH - Cytarabine/tu [Therapeutic Use] MH - Etoposide/tu [Therapeutic Use] MH - Female MH - Hematopoietic Stem Cell Transplantation/ae [Adverse Effects] MH - *Hematopoietic Stem Cell Transplantation/mt [Methods] MH - Hematopoietic Stem Cell Transplantation/mo [Mortality] MH - Humans MH - Immunocompetence MH - Lymphoma/co [Complications] MH - Lymphoma/mo [Mortality] MH - *Lymphoma/th [Therapy] MH - Male MH - Melphalan/tu [Therapeutic Use] MH - Middle Aged MH - Neurotoxicity Syndromes/et [Etiology] MH - Radiotherapy, Adjuvant MH - Recurrence MH - Remission Induction/mt [Methods] MH - Survival Rate MH - Transplantation, Autologous AB - The treatment of primary central nervous system lymphoma (PCNSL) has been considerably improved over recent years. In this article, we report six cases of PCNSL treated by first-line induction chemotherapy followed by intensive chemotherapy and autologous stem cell transplantation (ASCT). Six immunocompetent patients presenting with a PCNSL, confirmed by thoraco-abdomino-pelvic computer tomography scan and bone marrow biopsy, were treated with induction chemotherapy followed by BEAM intensive chemotherapy and ASCT and radiotherapy. At the end of the treatment, all the patients were in complete remission. After a median follow-up of 41.5 months (17-70 months), four patients were alive without signs of relapse (median survival: 35.5 months). Two patients died from relapse at 19 and 23 months. The neurotoxicity was low with epilepsy in one patient and persistent left side dysesthesia in another one. These results are fairly encouraging. Other studies with greater numbers of patients and longer follow-up are needed to confirm this study. RN - 04079A1RDZ (Cytarabine) RN - 6PLQ3CP4P3 (Etoposide) RN - Q41OR9510P (Melphalan) RN - U68WG3173Y (Carmustine) PS - BEAM regimen IS - 0902-4441 IL - 0902-4441 DI - EJH508 DO - https://dx.doi.org/10.1111/j.1600-0609.2005.00508.x PT - Clinical Trial PT - Journal Article ID - 16146534 [pubmed] ID - EJH508 [pii] ID - 10.1111/j.1600-0609.2005.00508.x [doi] PP - ppublish LG - English DP - 2005 Oct DC - 20050908 EZ - 2005/09/09 09:00 DA - 2005/10/19 09:00 DT - 2005/09/09 09:00 YR - 2005 ED - 20051018 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16146534 <558. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16170947 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Keuning H AU - Monne TK AU - IJsselsteijn WA AU - Houtsma AJ FA - Keuning, Hilde FA - Monne, Tom K J FA - IJsselsteijn, Wijnand A FA - Houtsma, Adrianus J M IN - Keuning, Hilde. Department of Technology Management, Eindhoven University of Technology, P.O. Box 513, 6500 MB, Eindhoven, Netherlands. hilde@keuning.com TI - The form of augmented force-feedback fields and the efficiency and satisfaction in computer-aided pointing tasks. SO - Human Factors. 47(2):418-29, 2005 Summer AS - Hum Factors. 47(2):418-29, 2005 Summer NJ - Human factors PI - Journal available in: Print PI - Citation processed from: Print JC - ge5, 0374660 IO - Hum Factors SB - Index Medicus SB - National Aeronautics and Space Administration (NASA) Journals CP - United States MH - Adult MH - Analysis of Variance MH - *Computer Peripherals MH - *Consumer Behavior MH - Efficiency MH - *Feedback MH - Female MH - Humans MH - Male MH - Sex Factors MH - *Task Performance and Analysis MH - *User-Computer Interface AB - This study investigates operation efficiency and user satisfaction for spatial and temporal shapes of augmented force-feedback fields to be used with computer pointing devices in target acquisition tasks. In an experiment, three different force-field shapes at two different mean force levels were compared, with an electromechanical force-feedback trackball as control device and with efficiency and user satisfaction as dependent variables. Efficiency was measured by the time required to perform a certain task, and user satisfaction was measured through a subjective rating procedure. Satisfaction results indicate that to a rough approximation, participants can be grouped into those who prefer high and those who prefer low force levels. Members of the former group were most satisfied with force fields with a gradual start and an abrupt ending. This force-field shape also proved to be the most efficient for both groups. When all participants were considered as a single group, none of the effects was found to be statistically significant. A gender effect was also found; in both preference groups women achieved significantly shorter task completion times than men. Actual or potential applications of this research include enabling computer interaction for people prone to repetitive strain injuries and the increment of efficiency and satisfaction in human-computer interaction in general. IS - 0018-7208 IL - 0018-7208 DO - https://dx.doi.org/10.1518/0018720054679560 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial ID - 16170947 [pubmed] ID - 10.1518/0018720054679560 [doi] PP - ppublish LG - English DP - 2005 Summer DC - 20050920 EZ - 2005/09/21 09:00 DA - 2005/10/14 09:00 DT - 2005/09/21 09:00 YR - 2005 ED - 20051013 RD - 20170214 UP - 20170215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=16170947 <559. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16170947 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Keuning H AU - Monne TK AU - IJsselsteijn WA AU - Houtsma AJ FA - Keuning, Hilde FA - Monne, Tom K J FA - IJsselsteijn, Wijnand A FA - Houtsma, Adrianus J M IN - Keuning, Hilde. Department of Technology Management, Eindhoven University of Technology, P.O. Box 513, 6500 MB, Eindhoven, Netherlands. hilde@keuning.com TI - The form of augmented force-feedback fields and the efficiency and satisfaction in computer-aided pointing tasks. SO - Human Factors. 47(2):418-29, 2005 Summer AS - Hum Factors. 47(2):418-29, 2005 Summer NJ - Human factors PI - Journal available in: Print PI - Citation processed from: Print JC - ge5, 0374660 IO - Hum Factors SB - Index Medicus SB - National Aeronautics and Space Administration (NASA) Journals CP - United States MH - Adult MH - Analysis of Variance MH - *Computer Peripherals MH - *Consumer Behavior MH - Efficiency MH - *Feedback MH - Female MH - Humans MH - Male MH - Sex Factors MH - *Task Performance and Analysis MH - *User-Computer Interface AB - This study investigates operation efficiency and user satisfaction for spatial and temporal shapes of augmented force-feedback fields to be used with computer pointing devices in target acquisition tasks. In an experiment, three different force-field shapes at two different mean force levels were compared, with an electromechanical force-feedback trackball as control device and with efficiency and user satisfaction as dependent variables. Efficiency was measured by the time required to perform a certain task, and user satisfaction was measured through a subjective rating procedure. Satisfaction results indicate that to a rough approximation, participants can be grouped into those who prefer high and those who prefer low force levels. Members of the former group were most satisfied with force fields with a gradual start and an abrupt ending. This force-field shape also proved to be the most efficient for both groups. When all participants were considered as a single group, none of the effects was found to be statistically significant. A gender effect was also found; in both preference groups women achieved significantly shorter task completion times than men. Actual or potential applications of this research include enabling computer interaction for people prone to repetitive strain injuries and the increment of efficiency and satisfaction in human-computer interaction in general. IS - 0018-7208 IL - 0018-7208 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial ID - 16170947 [pubmed] PP - ppublish LG - English DP - 2005 Summer DC - 20050920 EZ - 2005/09/21 09:00 DA - 2005/10/14 09:00 DT - 2005/09/21 09:00 YR - 2005 ED - 20051013 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16170947 <560. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15954959 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Meininger D AU - Byhahn C AU - Mierdl S AU - Westphal K AU - Zwissler B FA - Meininger, D FA - Byhahn, C FA - Mierdl, S FA - Westphal, K FA - Zwissler, B IN - Meininger, D. Department of Anaesthesiology, Intensive Care Medicine and Pain Control, J.W. Goethe-University Hospital, Frankfurt, Germany. dirk_meininger@gmx.de TI - Positive end-expiratory pressure improves arterial oxygenation during prolonged pneumoperitoneum. SO - Acta Anaesthesiologica Scandinavica. 49(6):778-83, 2005 Jul AS - Acta Anaesthesiol Scand. 49(6):778-83, 2005 Jul NJ - Acta anaesthesiologica Scandinavica PI - Journal available in: Print PI - Citation processed from: Print JC - 0370270 IO - Acta Anaesthesiol Scand SB - Index Medicus CP - England MH - Aged MH - Anesthesia MH - Carbon Dioxide/bl [Blood] MH - Endoscopy MH - Hemodynamics MH - Humans MH - Male MH - Middle Aged MH - *Oxygen/bl [Blood] MH - *Pneumoperitoneum, Artificial MH - *Positive-Pressure Respiration MH - Prostatectomy MH - Respiration, Artificial MH - Respiratory Function Tests MH - Treatment Outcome AB - BACKGROUND: Laparoscopic surgery usually requires the use of a pneumoperitoneum by insufflating gas in the peritoneal space. The gas most commonly used for insufflation is carbon dioxide. Increased intra-abdominal pressure causes cephalad displacement of the diaphragm resulting in compressed lung areas, which leads to formation of atelectasis, especially during mechanical ventilation. The aim of this prospective study was to investigate the effect of prolonged intraperitoneal gas insufflation on arterial oxygenation and hemodynamics during mechanical ventilation with and without positive end-expiratory pressure (PEEP). AB - METHODS: Twenty patients undergoing totally endoscopic robot-assisted radical prostatectomy were randomly allocated to one of two groups. In the PEEP group (n = 10) a constant PEEP of 5 cmH(2)O was used, whereas in the ZPEEP group (n = 10) no PEEP was used. AB - RESULTS: Application of PEEP (5 cmH(2)O) resulted in significantly higher P(a)O(2) levels after 3 h (182 +/- 49 vs. 224 +/- 35 mmHg) and 4 h (179 +/- 48 vs. 229 +/- 29 mmHg) of pneumoperitoneum; after desufflation, P(a)O(2) values decreased significantly below preinsufflation values. While there were no significant differences in heart rate, central venous pressure (CVP) and mean arterial blood pressure (MAP) during pneumoperitoneum between both groups, baseline values in CVP and MAP differed significantly between both groups with higher levels in the ZPEEP group. AB - CONCLUSION: The application of a constant positive airway pressure of 5 cmH(2)O preserves arterial oxygenation during prolonged pneumoperitoneum. RN - 142M471B3J (Carbon Dioxide) RN - S88TT14065 (Oxygen) IS - 0001-5172 IL - 0001-5172 DI - AAS713 DO - https://dx.doi.org/10.1111/j.1399-6576.2005.00713.x PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial ID - 15954959 [pubmed] ID - AAS713 [pii] ID - 10.1111/j.1399-6576.2005.00713.x [doi] PP - ppublish LG - English DP - 2005 Jul DC - 20050615 EZ - 2005/06/16 09:00 DA - 2005/10/14 09:00 DT - 2005/06/16 09:00 YR - 2005 ED - 20051013 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15954959 <561. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 16093986 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Webster TM AU - Herrell SD AU - Chang SS AU - Cookson MS AU - Baumgartner RG AU - Anderson LW AU - Smith JA Jr FA - Webster, Todd M FA - Herrell, S Duke FA - Chang, Sam S FA - Cookson, Michael S FA - Baumgartner, Roxelyn G FA - Anderson, Laura W FA - Smith, Joseph A Jr IN - Webster, Todd M. Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2765, USA. TI - Robotic assisted laparoscopic radical prostatectomy versus retropubic radical prostatectomy: a prospective assessment of postoperative pain. SO - Journal of Urology. 174(3):912-4; discussion 914, 2005 Sep AS - J Urol. 174(3):912-4; discussion 914, 2005 Sep NJ - The Journal of urology PI - Journal available in: Print PI - Citation processed from: Print JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Drug Administration Schedule MH - Humans MH - Infusions, Intravenous MH - Ketorolac/ad [Administration & Dosage] MH - *Laparoscopes MH - Male MH - Middle Aged MH - Outcome and Process Assessment (Health Care) MH - Pain Measurement MH - Pain, Postoperative/dt [Drug Therapy] MH - *Pain, Postoperative/et [Etiology] MH - Prospective Studies MH - *Prostatectomy/is [Instrumentation] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotics/is [Instrumentation] AB - PURPOSE: Laparoscopic prostatectomy, whether or not coupled with robotic assistance, is often considered less invasive than open radical retropubic prostatectomy (RRP). Minimal postoperative pain has been reported following robot assisted laparoscopic prostatectomy (RALP) but there have been few comparative studies with RRP. We compared perioperative narcotic use and patient reported pain in a prospective patient series. AB - MATERIALS AND METHODS: Between June 2003 and May 2004, 314 patients underwent radical prostatectomy at our institution, including RALP in 159, RRP in 154 and conversion in 1. All patients were treated on a postoperative clinical pathway that included 30 mg ketorolac intravenously immediately postoperatively, followed by 15 mg intravenously every 6 hours. No regional anesthesia (epidural/spinal) narcotics or patient controlled analgesic pumps were used. All narcotic use was converted to morphine sulfate equivalents for purpose of analysis. A Likert scale of 0 to 10 was used to assess pain on the day of surgery, and on postoperative days 1 and 14. AB - RESULTS: The total mean morphine sulfate equivalent +/- SD in patients in the RALP and RRP groups was low and, when corrected for length of stay, it was not statistically different (22.41 +/- 1.13 vs 23.01 +/- 1.16 mg, p = 0.72). Mean Likert pain perception scores were low at all time points in the RALP and RRP groups but statistically lower on the day of surgery in the RALP cohort (2.05 +/- 1.99 vs 2.60 +/- 2.25, p = 0.027). Patient reported mean pain scores were almost identical for RALP vs RRP on postoperative days 1 (1.76 +/- 1.87 vs 1.73 +/- 1.77, p = 0.880) and 14 (2.51 +/- 1.91 vs 2.42 +/- 1.84, p = 0.722). AB - CONCLUSIONS: Perioperative narcotic use and patient reported pain are low regardless of the surgical approach used for radical prostatectomy. RALP did not provide a clinically meaningful decrease in pain compared with RRP, primarily because of the low pain scores reported in each group. Outcomes other than pain will ultimately determine the role of laparoscopic radical prostatectomy and RALP. RN - YZI5105V0L (Ketorolac) IS - 0022-5347 IL - 0022-5347 DI - S0022-5347(01)68445-3 DO - https://dx.doi.org/10.1097/01.ju.0000169455.25510.ff PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 16093986 [pubmed] ID - S0022-5347(01)68445-3 [pii] ID - 10.1097/01.ju.0000169455.25510.ff [doi] PP - ppublish LG - English DP - 2005 Sep DC - 20050811 EZ - 2005/08/12 09:00 DA - 2005/09/29 09:00 DT - 2005/08/12 09:00 YR - 2005 ED - 20050928 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=16093986 <562. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15680820 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Reichenspurner H AU - Detter C AU - Deuse T AU - Boehm DH AU - Treede H AU - Reichart B FA - Reichenspurner, Hermann FA - Detter, Christian FA - Deuse, Tobias FA - Boehm, Dieter H FA - Treede, Hendrik FA - Reichart, Bruno IN - Reichenspurner, Hermann. Department of Cardiovascular Surgery, University Hospital Hamburg-Eppendorf, Hamburg, Germany. TI - Video and robotic-assisted minimally invasive mitral valve surgery: a comparison of the Port-Access and transthoracic clamp techniques. SO - Annals of Thoracic Surgery. 79(2):485-90; discussion 490-1, 2005 Feb AS - Ann Thorac Surg. 79(2):485-90; discussion 490-1, 2005 Feb NJ - The Annals of thoracic surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 15030100R IO - Ann. Thorac. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - Netherlands MH - Cardiopulmonary Bypass MH - *Catheters, Indwelling MH - Female MH - Humans MH - Length of Stay MH - Male MH - Middle Aged MH - *Mitral Valve/su [Surgery] MH - Mitral Valve Insufficiency/mo [Mortality] MH - *Mitral Valve Insufficiency/su [Surgery] MH - Retrospective Studies MH - *Robotics/mt [Methods] MH - Survival Rate MH - *Thoracotomy/mt [Methods] MH - Treatment Outcome MH - Video-Assisted Surgery/ae [Adverse Effects] MH - *Video-Assisted Surgery/mt [Methods] AB - BACKGROUND: In order to assess different surgical techniques for video-assisted minimally invasive mitral valve surgery, a retrospective study was undertaken comparing the Port-Access system (Cardiovations, Ethicon Inc, Somerville, NJ) and the transthoracic clamp technique. AB - METHODS: In 120 patients mitral valve surgery was performed through a small right minithoracotomy using either the Port-Access endovascular cardiopulmonary bypass system (Port-Access, n = 60) or the transthoracic clamp technique (MICRO, n = 60). Mean patient age was 61.5 +/- 10.5 years (81 patients with isolated mitral valve insufficiency, 39 patients with combined mitral valve disease). AB - RESULTS: Eighty-one (67.5%) patients underwent mitral valve repair and 39 (32.5%) patients had valve replacement. Mean time of surgery was 4.5 +/- 3.5 and 4.1 +/- 3.2 hours (p = 0.07), aortic cross-clamp time 89 +/- 69 and 78 +/- 65 minutes (p = 0.08), mean intensive care unit stay 1.5 +/- 2.1 and 1.6 +/- 2.5 days (p = ns), and hospital stay 9.0 +/- 10.5 and 9.2 +/- 9.7 days (p = ns) in the Port-Access and MICRO groups, respectively. In the Port-Access group, there were 6 reexplorations for bleeding, one perforation of the right ventricle with the endopulmonary vent, and 2 reconstructions of the femoral artery necessary after femoral cannulation, compared to one reexploration for bleeding in the MICRO group. There was only one minor paravalvular leak after replacement and 2 cases of residual greater than or equal to grade II mitral valve regurgitation after mitral valve repair in the Port-Access group, necessitating reoperation. In both groups, there was no mortality, no cerebrovascular accident, no aortic dissection, and no conversion to sternotomy. AB - CONCLUSIONS: Minimally invasive mitral valve surgery has become a standard approach for isolated mitral valve operations at our institution. The MICRO technique tends to shorten the time of surgery and aortic cross-clamping and reduces perioperative costs by simplifying the operative procedure. ES - 1552-6259 IL - 0003-4975 DI - S0003-4975(04)01602-9 DO - https://dx.doi.org/10.1016/j.athoracsur.2004.06.120 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 15680820 [pubmed] ID - S0003-4975(04)01602-9 [pii] ID - 10.1016/j.athoracsur.2004.06.120 [doi] PP - ppublish PH - 2004/06/11 [accepted] LG - English DP - 2005 Feb DC - 20050131 EZ - 2005/02/01 09:00 DA - 2005/09/24 09:00 DT - 2005/02/01 09:00 YR - 2005 ED - 20050923 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15680820 <563. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15680819 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Reade CC AU - Johnson JO AU - Bolotin G AU - Freund WL Jr AU - Jenkins NL AU - Bower CE AU - Masroor S AU - Kypson AP AU - Nifong LW AU - Chitwood WR Jr FA - Reade, Clifton C FA - Johnson, James O FA - Bolotin, Gil FA - Freund, William L Jr FA - Jenkins, Nelson L FA - Bower, Curtis E FA - Masroor, Saqib FA - Kypson, Alan P FA - Nifong, L Wiley FA - Chitwood, W Randolph Jr IN - Reade, Clifton C. Division of Cardiothoracic and Vascular Surgery, The Brody School of Medicine at East Carolina University, Greenville, North Carolina 27858, USA. TI - Combining robotic mitral valve repair and microwave atrial fibrillation ablation: techniques and initial results. SO - Annals of Thoracic Surgery. 79(2):480-4, 2005 Feb AS - Ann Thorac Surg. 79(2):480-4, 2005 Feb NJ - The Annals of thoracic surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 15030100R IO - Ann. Thorac. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - Netherlands MH - Aged MH - Atrial Fibrillation/co [Complications] MH - *Atrial Fibrillation/su [Surgery] MH - Cardiopulmonary Bypass/mt [Methods] MH - Humans MH - Length of Stay MH - *Microwaves/tu [Therapeutic Use] MH - Middle Aged MH - *Mitral Valve/su [Surgery] MH - Mitral Valve Insufficiency/co [Complications] MH - *Mitral Valve Insufficiency/su [Surgery] MH - *Robotics/mt [Methods] MH - Thoracotomy/mt [Methods] MH - Treatment Outcome AB - BACKGROUND: Left atrial microwave ablation for atrial fibrillation has become popular for isolating autonomous atrial foci. Previously, mitral valve repairs (MVP) with atrial fibrillation ablation have been performed through sternotomy. We present a technique that combines robotic MVP with left atrial fibrillation ablation. AB - METHODS: Through a 4-cm right minithoracotomy and using cardiopulmonary bypass, the transverse and oblique sinuses are accessed. A Flex-10 microwave catheter is passed around the pulmonary veins, and after weaning from cardiopulmonary bypass, peripulmonary vein microwave ablations are performed. After cardioplegic arrest, the da Vinci system is used to manipulate the catheter to create endocardial lesions around the left atrial appendage. Another endocardial lesion is made connecting the pulmonary venous line with the mitral annulus near P3. The left atrial appendage is closed, and the MVP performed robotically. Data are expressed as mean +/- standard deviation. AB - RESULTS: Sixteen patients underwent this combined procedure, with 80% returning to a normal sinus rhythm at 6 weeks and 73% remaining in normal sinus rhythm at 6 months. Only 1 patient was in atrial fibrillation at 6 months. The ablation procedure added 42 +/- 16.1 minutes to a robotic MVP. The average length of hospital stay was 6.3 +/- 2.2 days, 1.3 days longer than the mean of the prior 50 consecutive robotic MVP patients without a concomitant ablation. AB - CONCLUSIONS: Robotic microwave ablation during robotic MVP is a safe, effective way to resolve atrial fibrillation. These methods offer a promising prelude to the combined totally endoscopic treatment of atrial arrhythmias and mitral insufficiency. ES - 1552-6259 IL - 0003-4975 DI - S0003-4975(04)01645-5 DO - https://dx.doi.org/10.1016/j.athoracsur.2004.07.078 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 15680819 [pubmed] ID - S0003-4975(04)01645-5 [pii] ID - 10.1016/j.athoracsur.2004.07.078 [doi] PP - ppublish PH - 2004/07/29 [accepted] LG - English DP - 2005 Feb DC - 20050131 EZ - 2005/02/01 09:00 DA - 2005/09/24 09:00 DT - 2005/02/01 09:00 YR - 2005 ED - 20050923 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15680819 <564. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15680812 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Savitt MA AU - Gao G AU - Furnary AP AU - Swanson J AU - Gately HL AU - Handy JR FA - Savitt, Michael A FA - Gao, Guangquiang FA - Furnary, Anthony P FA - Swanson, Jeffrey FA - Gately, Hugh L FA - Handy, John R IN - Savitt, Michael A. Providence St. Vincent Heart and Vascular Institute, Portland, Oregon 97225, USA. msavitt@starrwood.com TI - Application of robotic-assisted techniques to the surgical evaluation and treatment of the anterior mediastinum. SO - Annals of Thoracic Surgery. 79(2):450-5; discussion 455, 2005 Feb AS - Ann Thorac Surg. 79(2):450-5; discussion 455, 2005 Feb NJ - The Annals of thoracic surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 15030100R IO - Ann. Thorac. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - Netherlands MH - Adult MH - Aged MH - *Biopsy/mt [Methods] MH - Female MH - Follow-Up Studies MH - Humans MH - Length of Stay MH - Male MH - *Mediastinal Diseases/di [Diagnosis] MH - Mediastinal Diseases/pa [Pathology] MH - *Mediastinal Diseases/su [Surgery] MH - Middle Aged MH - Myasthenia Gravis/di [Diagnosis] MH - Myasthenia Gravis/su [Surgery] MH - *Robotics/mt [Methods] MH - *Thymectomy/mt [Methods] MH - Thymoma/di [Diagnosis] MH - Thymoma/pa [Pathology] MH - Thymoma/su [Surgery] MH - *Thymus Neoplasms/di [Diagnosis] MH - Thymus Neoplasms/pa [Pathology] MH - *Thymus Neoplasms/su [Surgery] MH - Thyroid Neoplasms/di [Diagnosis] MH - Thyroid Neoplasms/pa [Pathology] MH - Thyroid Neoplasms/su [Surgery] MH - Treatment Outcome AB - BACKGROUND: We report our initial experience with the application of robotic-assisted technologies to the treatment of diseases of the anterior mediastinum. AB - METHODS: Between October 2001 and December 2003, 18 consecutive patients with anterior mediastinal masses were referred for diagnosis and treatment. Fifteen patients underwent robotic-assisted surgery with the da Vinci robotic system. A single surgical team performed all operations. Resection was accomplished by either median sternotomy or robotic-assisted techniques. AB - RESULTS: Fourteen patients underwent successful robotic-assisted thymectomy. One patient underwent robotic-assisted biopsy of a mass that was later determined to be a poorly differentiated carcinoma, 3 patients underwent complete thymectomy by median sternotomy for biopsy-proven extracapsular thymoma, 7 patients had thymoma, and 3 had myasthenia gravis. There were 2 patients each with benign thymic cysts and thymic hyperplasia. Primary thymic carcinoid, thymolipoma, papillary thyroid cancer, and poorly differentiated carcinoma were present in 1 patient each. No conversions, intraoperative complications, or deaths occurred in the 15 patients who underwent robotic-assisted resection. The mean operative time was 96 minutes (range 62 to 132 minutes). The mean robotic time was 48 minutes (range 22 to 76). The median hospital stay was 2 days. All patients are doing well, with a median follow-up of 1 year. AB - CONCLUSIONS: Robotic-assisted surgery of the anterior mediastinum, and particularly thymectomy, can be performed safely and efficiently. The increased visualization and instrument dexterity afforded by this technology provides an optimal minimally invasive approach to the anterior mediastinum. From this experience we have formulated a comprehensive treatment algorithm for the surgical evaluation and treatment of patients with anterior mediastinal diseases. ES - 1552-6259 IL - 0003-4975 DI - S0003-4975(04)01584-X DO - https://dx.doi.org/10.1016/j.athoracsur.2004.07.022 PT - Clinical Trial PT - Journal Article ID - 15680812 [pubmed] ID - S0003-4975(04)01584-X [pii] ID - 10.1016/j.athoracsur.2004.07.022 [doi] PP - ppublish PH - 2004/07/14 [accepted] LG - English DP - 2005 Feb DC - 20050131 EZ - 2005/02/01 09:00 DA - 2005/09/24 09:00 DT - 2005/02/01 09:00 YR - 2005 ED - 20050923 RD - 20050131 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15680812 <565. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15942584 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Nifong LW AU - Chitwood WR AU - Pappas PS AU - Smith CR AU - Argenziano M AU - Starnes VA AU - Shah PM FA - Nifong, L Wiley FA - Chitwood, W R FA - Pappas, P S FA - Smith, C R FA - Argenziano, M FA - Starnes, V A FA - Shah, P M IN - Nifong, L Wiley. Brody School of Medicine at East Carolina University, Pitt County Memorial Hospital, Greenville, NC, USA. nifongL@mail.ecu.edu TI - Robotic mitral valve surgery: a United States multicenter trial. SO - Journal of Thoracic & Cardiovascular Surgery. 129(6):1395-404, 2005 Jun AS - J Thorac Cardiovasc Surg. 129(6):1395-404, 2005 Jun NJ - The Journal of thoracic and cardiovascular surgery PI - Journal available in: Print PI - Citation processed from: Print JC - k9j, 0376343 IO - J. Thorac. Cardiovasc. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - Cardiac Surgical Procedures/is [Instrumentation] MH - Cardiac Surgical Procedures/mt [Methods] MH - Echocardiography, Transesophageal MH - Female MH - Humans MH - Male MH - Middle Aged MH - Mitral Valve Insufficiency/dg [Diagnostic Imaging] MH - *Mitral Valve Insufficiency/su [Surgery] MH - Prospective Studies MH - *Robotics MH - United States AB - OBJECTIVE: In a prospective phase II Food and Drug Administration trial, robotic mitral valve repairs were performed in 112 patients at 10 centers by using the da Vinci surgical system. The safety of performing valve repairs with computerized telemanipulation was studied. AB - METHODS: After institutional review board approval, informed consent was obtained. Patients had moderate to severe mitral regurgitation. Operative technique included peripheral cardiopulmonary bypass, a 4- to 5-cm right minithoracotomy, a transthoracic aortic crossclamp, and antegrade cardioplegia. The successful study end point was grade 0 or 1 mitral regurgitation by transthoracic echocardiography at 1 month after surgery. AB - RESULTS: Valve repairs included quadrangular resections, sliding plasties, edge-to-edge approximations, and both chordal transfers and replacements. The average age was 56.4 +/- 0.09 years (mean +/- SEM). There were 77 (68.8%) men and 35 (31.2%) women. Valve pathology was myxomatous degeneration in 105 (91.1%), and 103 (92.0%) had type II leaflet prolapse. Leaflet repair times averaged 36.7 +/- 0.2 minutes, with annuloplasty times of 39.6 +/- 0.1 minutes. Total robot, aortic crossclamp, and cardiopulmonary bypass times were 77.9 +/- 0.3 minutes, 2.1 +/- 0.1 hours, and 2.8 +/- 0.1 hours, respectively. On 1-month transthoracic echocardiography, 9 (8.0%) had grade 2 mitral regurgitation, and 6 (5.4%) of these had reoperations (5 replacements and 1 repair). There were no deaths, strokes, or device-related complications. AB - CONCLUSIONS: Multiple surgical teams performed robotic mitral valve repairs safely early in development of this procedure, with a reoperation rate of 5.4%. Advancements in robotic design and adjunctive technologies may help in the evolution of this minimally invasive technique by decreasing operative times. IS - 0022-5223 IL - 0022-5223 DI - S0022522304011729 DO - https://dx.doi.org/10.1016/j.jtcvs.2004.07.050 PT - Clinical Trial PT - Clinical Trial, Phase II PT - Journal Article PT - Multicenter Study PT - Research Support, Non-U.S. Gov't ID - 15942584 [pubmed] ID - S0022522304011729 [pii] ID - 10.1016/j.jtcvs.2004.07.050 [doi] PP - ppublish LG - English DP - 2005 Jun DC - 20050608 EZ - 2005/06/09 09:00 DA - 2005/07/27 09:00 DT - 2005/06/09 09:00 YR - 2005 ED - 20050726 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15942584 <566. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15947662 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Patel VR AU - Tully AS AU - Holmes R AU - Lindsay J FA - Patel, Vipul R FA - Tully, A S FA - Holmes, R FA - Lindsay, J IN - Patel, Vipul R. Urology Centers of Alabama, Birmingham, Alabama, USA. VPatel2171@aol.com TI - Robotic radical prostatectomy in the community setting--the learning curve and beyond: initial 200 cases. SO - Journal of Urology. 174(1):269-72, 2005 Jul AS - J Urol. 174(1):269-72, 2005 Jul NJ - The Journal of urology PI - Journal available in: Print PI - Citation processed from: Print JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Humans MH - Male MH - Middle Aged MH - Prospective Studies MH - *Prostatectomy/mt [Methods] MH - *Prostatic Neoplasms/su [Surgery] MH - *Robotics AB - PURPOSE: The introduction of robotic assistance has the potential to improve surgical outcomes and reduce the steep learning curve associated with conventional laparoscopic radical prostatectomy. We report on our experience with robotic radical prostatectomy in the community setting. AB - MATERIALS AND METHODS: A total of 200 patients underwent robotic radical prostatectomy during 18 months. Prospective data collection included a quality of life (Expanded Prostate Cancer Index Composite) questionnaire, basic demographics, prostate specific antigen (PSA), clinical stage and Gleason grade. Operative outcome measures included operative time, estimated blood loss and complications. Postoperative outcome measures included hospital stay, catheter time, pathology, PSA and return of continence. AB - RESULTS: Average operative time was 141 minutes with an estimated blood loss of 75 cc. The intraoperative complication rate was 1% with no mortality, reexploration or transfusion. Of the patients 95% were discharged home on postoperative day 1 (1 to 3) with hematocrit averaging 34.5 (range 25 to 45). The average difference in preoperative and postoperative hematocrit was 3 points (range -2 to 15). Average catheter time was 7.2 days (range 5 to 15). The positive margin rate was 10.5% for the entire series, 5.7% for T2 tumors, 28.5% (T3a), 20% (T3b) and 33% (T4a). Of the patients 95% had undetectable PSA (less than 0.1 ng/ml) at average followup of 9.7 months. Continence at 1, 3, 6, 9 and 12 months was 47%, 78%, 89%, 92% and 98%, respectively. AB - CONCLUSIONS: Our initial experience with robotic radical prostatectomy is promising. The learning curve was approximately 20 to 25 cases. With a structured methodical approach we were able to implement robotics safely and effectively into our community practice with minimal patient morbidity, and good oncological and functional outcomes. IS - 0022-5347 IL - 0022-5347 DI - S0022-5347(05)60102-4 DO - https://dx.doi.org/10.1097/01.ju.0000162082.12962.40 PT - Clinical Trial PT - Journal Article ID - 15947662 [pubmed] ID - S0022-5347(05)60102-4 [pii] ID - 10.1097/01.ju.0000162082.12962.40 [doi] PP - ppublish LG - English DP - 2005 Jul DC - 20050610 EZ - 2005/06/11 09:00 DA - 2005/07/26 09:00 DT - 2005/06/11 09:00 YR - 2005 ED - 20050725 RD - 20050610 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15947662 <567. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15811151 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Schittek Janda M AU - Tani Botticelli A AU - Mattheos N AU - Nebel D AU - Wagner A AU - Nattestad A AU - Attstrom R FA - Schittek Janda, M FA - Tani Botticelli, A FA - Mattheos, N FA - Nebel, D FA - Wagner, A FA - Nattestad, A FA - Attstrom, R IN - Schittek Janda, M. Department of Periodontology and Centre for Educational Research and Technology, Centre for Oral Health Sciences, Malmo University, Malmo, Sweden. martin.janda@od.mah.se TI - Computer-mediated instructional video: a randomised controlled trial comparing a sequential and a segmented instructional video in surgical hand wash. SO - European Journal of Dental Education. 9(2):53-8, 2005 May AS - Eur J Dent Educ. 9(2):53-8, 2005 May NJ - European journal of dental education : official journal of the Association for Dental Education in Europe PI - Journal available in: Print PI - Citation processed from: Print JC - 9712132, c1l IO - Eur J Dent Educ SB - Dental Journals CP - England MH - Attitude of Health Personnel MH - *Computer-Assisted Instruction MH - *Education, Dental/mt [Methods] MH - Educational Measurement MH - *Hand Disinfection MH - Humans MH - Students, Dental/px [Psychology] MH - *Surgery, Oral/ed [Education] MH - Surveys and Questionnaires MH - *Videotape Recording/mt [Methods] AB - BACKGROUND: Video-based instructions for clinical procedures have been used frequently during the preceding decades. AB - AIM: To investigate in a randomised controlled trial the learning effectiveness of fragmented videos vs. the complete sequential video and to analyse the attitudes of the user towards video as a learning aid. AB - MATERIALS AND METHODS: An instructional video on surgical hand wash was produced. The video was available in two different forms in two separate web pages: one as a sequential video and one fragmented into eight short clips. Twenty-eight dental students in the second semester were randomised into an experimental (n = 15) and a control group (n = 13). The experimental group used the fragmented form of the video and the control group watched the complete one. The use of the videos was logged and the students were video taped whilst undertaking a test hand wash. The videos were analysed systematically and blindly by two independent clinicians. The students also performed a written test concerning learning outcome from the videos as well as they answered an attitude questionnaire. AB - RESULTS: The students in the experimental group watched the video significantly longer than the control group. There were no significant differences between the groups with regard to the ratings and scores when performing the hand wash. The experimental group had significantly better results in the written test compared with those of the control group. There was no significant difference between the groups with regard to attitudes towards the use of video for learning, as measured by the Visual Analogue Scales. Most students in both groups expressed satisfaction with the use of video for learning. AB - CONCLUSION: The students demonstrated positive attitudes and acceptable learning outcome from viewing CAL videos as a part of their pre-clinical training. Videos that are part of computer-based learning settings would ideally be presented to the students both as a segmented and as a whole video to give the students the option to choose the form of video which suits the individual student's learning style. IS - 1396-5883 IL - 1396-5883 DI - EJE366 DO - https://dx.doi.org/10.1111/j.1600-0579.2004.00366.x PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial ID - 15811151 [pubmed] ID - EJE366 [pii] ID - 10.1111/j.1600-0579.2004.00366.x [doi] PP - ppublish LG - English DP - 2005 May DC - 20050406 EZ - 2005/04/07 09:00 DA - 2005/05/11 09:00 DT - 2005/04/07 09:00 YR - 2005 ED - 20050510 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15811151 <568. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15223421 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bolton JW AU - Connally JE FA - Bolton, J W Randolph FA - Connally, Jackie E IN - Bolton, J W Randolph. Carolina Heart Institute, Greenwood, South Carolina 29648, USA. rbolton@carolinaheartinstitute.com TI - Results of a Phase One study on robotically assisted myocardial revascularization on the beating heart. SO - Annals of Thoracic Surgery. 78(1):154-8; discussion 154-8, 2004 Jul AS - Ann Thorac Surg. 78(1):154-8; discussion 154-8, 2004 Jul NJ - The Annals of thoracic surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - 15030100R IO - Ann. Thorac. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - Netherlands MH - Adult MH - Aged MH - Angina, Unstable/su [Surgery] MH - Coronary Angiography MH - *Coronary Artery Bypass, Off-Pump/is [Instrumentation] MH - Coronary Artery Bypass, Off-Pump/mt [Methods] MH - Echocardiography, Stress MH - Equipment Design MH - Feasibility Studies MH - Female MH - Follow-Up Studies MH - Graft Occlusion, Vascular/dg [Diagnostic Imaging] MH - Humans MH - *Internal Mammary-Coronary Artery Anastomosis/is [Instrumentation] MH - Internal Mammary-Coronary Artery Anastomosis/mt [Methods] MH - Male MH - Middle Aged MH - Myocardial Infarction/et [Etiology] MH - Postoperative Complications MH - Reoperation MH - *Robotics MH - Surgical Wound Infection/et [Etiology] MH - Treatment Outcome AB - BACKGROUND: The objective of this study was to evaluate the feasibility of computer assisted myocardial revascularization on the beating heart. AB - METHODS: Ten patients underwent at least one robotically assisted internal mammary artery (IMA) anastomosis utilizing the da Vinci surgical system (Intuitive Surgical, Inc, Mountain View, CA) performed through an open incision as part of standard multivessel off pump revascularization. Following chest closure a selective IMA angiogram was performed to assess patency. Three month follow-up included a stress echocardiogram. AB - RESULTS: There were 12 anastomoses performed in 10 patients. The average age was 61 years with a mean ejection fraction of 56%. No patient required inotropic support. Eight of 10 patients were found to have fully patent IMA anastomoses by angiogram. One patient was noted to have an occluded left anterior descending coronary artery distal to the anastomosis and one had occlusion at the anastomosis. Both patients had immediate manual revision of the anastomosis. One patient who required anastomotic revision experienced postoperative myocardial infarction and sternal wound infection requiring pectoralis flaps. AB - CONCLUSIONS: Because robotic instrumentation is meant for closed chest procedures, there were major issues with positioning of the robotic arms in this study since the chest was open. Although two patients required anastomotic revision, there were no complications or technical failures related to the robotic system. Thus, based upon this study robotically assisted beating heart revascularization appears to be feasible, safe, and effective. Further evaluation will be necessary to determine the role of robotically assisted totally endoscopic coronary artery bypass on the beating heart in the United States. ES - 1552-6259 IL - 0003-4975 DI - S0003497504003819 DO - https://dx.doi.org/10.1016/j.athoracsur.2004.01.036 PT - Clinical Trial PT - Clinical Trial, Phase I PT - Journal Article ID - 15223421 [pubmed] ID - 10.1016/j.athoracsur.2004.01.036 [doi] ID - S0003497504003819 [pii] PP - ppublish PH - 2004/01/22 [accepted] LG - English DP - 2004 Jul DC - 20040629 EZ - 2004/06/30 05:00 DA - 2005/05/06 09:00 DT - 2004/06/30 05:00 YR - 2004 ED - 20050505 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15223421 <569. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15621321 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Leonard L AU - Sirkett D AU - Mullineux G AU - Giddins GE AU - Miles AW FA - Leonard, L FA - Sirkett, D FA - Mullineux, G FA - Giddins, G E B FA - Miles, A W IN - Leonard, L. Royal United Hospital, Foxhill, The Old Rope Walk, Tetbury, GLOS GL8 8XQ, Bath, UK. lisa.leonard@virgin.net TI - Development of an in-vivo method of wrist joint motion analysis. SO - Clinical Biomechanics. 20(2):166-71, 2005 Feb AS - Clin Biomech. 20(2):166-71, 2005 Feb NJ - Clinical biomechanics (Bristol, Avon) PI - Journal available in: Print PI - Citation processed from: Print JC - 8611877, dgl IO - Clin Biomech (Bristol, Avon) SB - Index Medicus CP - England MH - Algorithms MH - Computer Simulation MH - Equipment Design MH - Equipment Failure Analysis MH - Humans MH - Image Interpretation, Computer-Assisted/mt [Methods] MH - Imaging, Three-Dimensional/is [Instrumentation] MH - *Imaging, Three-Dimensional/mt [Methods] MH - *Magnetics MH - *Models, Biological MH - *Movement/ph [Physiology] MH - Physical Examination/is [Instrumentation] MH - *Physical Examination/mt [Methods] MH - Pilot Projects MH - *Range of Motion, Articular/ph [Physiology] MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Wrist Joint/ah [Anatomy & Histology] MH - *Wrist Joint/ph [Physiology] AB - BACKGROUND: A clinically applicable method of plotting wrist joint motion in three-dimensions has not been described. Computer modelling has been used to improve joint arthroplasty elsewhere in the body. We aimed to develop a method of measuring, and modelling, wrist joint motion that could potentially be used to improve the kinematic performance of wrist arthroplasty designs. AB - METHODS: An electromagnetic system was used to record wrist motion in three-dimensions. A small pilot study attempted to assess repeatability. A larger group of volunteers with normal wrists was also studied. An iterative computer model, using a two-axis hinge, was developed. One output from this model, the offset of the two axes of motion, is presented as an example of the possible applications of this method of analysis. AB - FINDINGS: For any one individual, in the pilot study, the offset of the axes calculated was relatively reproducible. Between individuals the difference in the offset of the axes was more marked. In 99 normal sets of data the mean axis offset was 6.8mm (range 28 mm to -21 mm) A positive value represented the radio-ulnar deviation axis placed distal to the flexion-extension axis. AB - INTERPRETATION: The three-dimensional motion plots generated using this method could be used clinically to follow disease progression or recovery following surgery. The computer modelling method described has potential applications, if further refined, to wrist joint arthroplasty design. IS - 0268-0033 IL - 0268-0033 DI - S0268-0033(04)00214-1 DO - https://dx.doi.org/10.1016/j.clinbiomech.2004.09.005 PT - Clinical Trial PT - Journal Article PT - Validation Studies ID - 15621321 [pubmed] ID - S0268-0033(04)00214-1 [pii] ID - 10.1016/j.clinbiomech.2004.09.005 [doi] PP - ppublish PH - 2003/04/08 [received] PH - 2004/09/01 [accepted] LG - English DP - 2005 Feb DC - 20041228 EZ - 2004/12/29 09:00 DA - 2005/04/29 09:00 DT - 2004/12/29 09:00 YR - 2005 ED - 20050428 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15621321 <570. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15727280 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hering K AU - Harvan J AU - Dangelo M AU - Jasinski D FA - Hering, Keith FA - Harvan, Jeffery FA - Dangelo, Matthew FA - Jasinski, Donna IN - Hering, Keith. Kaiser Permanente, San Francisco, CA, USA. TI - The use of a computer website prior to scheduled surgery (a pilot study): impact on patient information, acquisition, anxiety level, and overall satisfaction with anesthesia care. SO - AANA Journal. 73(1):29-33, 2005 Feb AS - AANA J. 73(1):29-33, 2005 Feb NJ - AANA journal PI - Journal available in: Print PI - Citation processed from: Print JC - 0431420 IO - AANA J SB - Nursing Journal CP - United States MH - Adult MH - Aged MH - Analysis of Variance MH - *Anesthesia MH - Anxiety/pc [Prevention & Control] MH - *Computer-Assisted Instruction MH - Female MH - Humans MH - *Internet MH - Male MH - Middle Aged MH - Nurse Anesthetists MH - *Patient Education as Topic/mt [Methods] MH - Patient Satisfaction MH - Pilot Projects MH - *Preoperative Care AB - Scheduled surgery can often be a stressful time for patients. While anesthesia providers give a full explanation of care to the patient, research suggests that anxiety and time constraints imposed by the system may hinder the amount and quality of information provided. Use of technology to augment dissemination of information may have an impact. The purpose of this study was to determine the impact of a website on: (1) preoperative patient education, (2) patient anxiety, and (3) patient satisfaction with anesthesia care. The week prior to surgery, 64 ASA class I and II subjects at a 350-bed urban university affiliated hospital completed a demographic questionnaire, State Trait Anxiety Inventory (STAI) and modified Standard Anesthesia Learning Test (mSALT), and the experimental group was given website information. On the day of surgery, all subjects completed the STAI and mSALT. Before discharge, subjects rated satisfaction. The experimental group had a significant increase in posttest mSALT scores (P = .004). Neither the experimental nor the control group had a significant change in posttest state anxiety (P = .279 and .762) or trait anxiety (P = .823 and.570). The experimental group differed significantly from the control group in satisfaction with teaching (P = .019). IS - 0094-6354 IL - 0094-6354 PT - Clinical Trial PT - Controlled Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 15727280 [pubmed] PP - ppublish LG - English DP - 2005 Feb DC - 20050224 EZ - 2005/02/25 09:00 DA - 2005/03/30 09:00 DT - 2005/02/25 09:00 YR - 2005 ED - 20050329 RD - 20071115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15727280 <571. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15529954 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Korb W AU - Engel D AU - Boesecke R AU - Eggers G AU - Kotrikova B AU - Marmulla R AU - Raczkowsky J AU - Worn H AU - Muhling J AU - Hassfeld S FA - Korb, Werner FA - Engel, Dirk FA - Boesecke, Robert FA - Eggers, Georg FA - Kotrikova, Bibiana FA - Marmulla, Rudiger FA - Raczkowsky, Jorg FA - Worn, Heinz FA - Muhling, Joachim FA - Hassfeld, Stefan IN - Korb, Werner. Department of Maxillofacial and Craniofacial Surgery, Ruprecht-Karls-University Heidelberg, Heidelberg, Germany. Werner_korb@med.uni-heidelberg.de TI - Development and first patient trial of a surgical robot for complex trajectory milling. SO - Computer Aided Surgery. 8(5):247-56, 2003 AS - Comput Aided Surg. 8(5):247-56, 2003 NJ - Computer aided surgery : official journal of the International Society for Computer Aided Surgery PI - Journal available in: Print PI - Citation processed from: Print JC - cuk, 9708375 IO - Comput. Aided Surg. SB - Index Medicus CP - England MH - *Craniotomy/is [Instrumentation] MH - Craniotomy/mt [Methods] MH - Humans MH - *Robotics MH - *Surgery, Computer-Assisted/is [Instrumentation] AB - OBJECTIVE: Today's surgical robots normally perform "simple" trajectories, e.g., assisting as tool-holding devices in neurosurgery, or milling linear paths for cavities in total hip replacement. From a clinical point of view, it is still a complex undertaking to implement robots in the operating room. Until now, robot systems have not been used in patient trials to mill "complex" trajectories, which involve many positional and orientation changes and are often necessary in cranio-maxillofacial (CMF) surgery. This paper presents the RobaCKa surgical robot system, which allows more precise execution of surgical interventions and milling of "complex" trajectories. AB - MATERIALS AND METHODS: The main components of the RobaCKa system are a (former) CASPAR robot system, a POLARIS system, and a force-torque sensor. AB - RESULTS: In the first patient trial (April 2003) the planned trajectory was executed with an error of 0.66 +/- 0.2 mm. AB - CONCLUSIONS: The use of former industrial robots for surgical applications is possible but complex. The advantages are improved precision and quality and the possibility of documentation. The use of such systems is normally limited to research institutions or large clinics, because it is hardly possible to implement the necessary technical and logistic efforts in routine surgical work. IS - 1092-9088 IL - 1092-9088 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 15529954 [pubmed] PP - ppublish LG - English DP - 2003 DC - 20041108 EZ - 2004/11/09 09:00 DA - 2005/03/11 09:00 DT - 2004/11/09 09:00 YR - 2003 ED - 20050310 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=15529954 <572. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15655620 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Chrissidis T AU - Saliangas K AU - Economou A AU - Nikoloudis N AU - Andreadis E AU - Prodromou K AU - Georgakis K FA - Chrissidis, T FA - Saliangas, K FA - Economou, A FA - Nikoloudis, N FA - Andreadis, E FA - Prodromou, K FA - Georgakis, K IN - Chrissidis, T. Department of Surgery, General Hospital of Edessa, Terma Egnatias, Edessa, Greece. tchris@hol.gr TI - Mass screening for colorectal cancer: compliance in Almopea Region. SO - Techniques in Coloproctology. 8 Suppl 1:s193-5, 2004 Nov AS - Tech Coloproctol. 8 Suppl 1:s193-5, 2004 Nov NJ - Techniques in coloproctology PI - Journal available in: Print PI - Citation processed from: Print JC - 9613614 IO - Tech Coloproctol SB - Index Medicus CP - Italy MH - Age Distribution MH - Aged MH - *Colonoscopy/mt [Methods] MH - *Colorectal Neoplasms/di [Diagnosis] MH - Colorectal Neoplasms/ep [Epidemiology] MH - Female MH - Greece/ep [Epidemiology] MH - Health Education MH - Humans MH - Incidence MH - Male MH - *Mass Screening/og [Organization & Administration] MH - Middle Aged MH - *Occult Blood MH - Patient Compliance MH - Program Development MH - Program Evaluation MH - Risk Factors MH - Rural Population MH - Sex Distribution AB - Colorectal cancer (CRC) is the second leading cause of cancer-related morbidity and mortality in Europe and the United States. Planning for a CRC screening began in co-operation with local authorities (Pella Prefecture sponsored test kits). Our aims were to develop a screening programme for colorectal cancer using the faecal occult blood test (FOBT) in Almopea province, and to investigate the compliance of local farmers population. Cancer statistics data from Almopea have been analysed and they showed higher colorectal cancer incidence compared to the rest of Greece. We designed a one-time FOBT screening programme on the Surgery Department computer Network, in which we listed 8963 subjects, over 50 years of age. From them, 4189 underwent 3 days FOBT, and the rest were our control group. The method of successive visits to each community by the medical team and educational meeting was chosen. For allocation and gathering of tests, teams of volunteers have been organised. In case of positive FOBT (176 subjects), total colonoscopy was performed. Seventeen (17) polypoids (in 15 patients) and 20 cases of diverticulosis were detected. The compliance of FOBT group was 49% (from 4189). Colonoscopy accepted 89% from 176 patients with positive test. We concluded that our study shows poor compliance of screening population. There is a need for co-operation of medical services, local authorities, media and volunteers support organising. IS - 1123-6337 IL - 1123-6337 DO - https://dx.doi.org/10.1007/s10151-004-0154-s PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 15655620 [pubmed] ID - 10.1007/s10151-004-0154-s [doi] PP - ppublish LG - English DP - 2004 Nov DC - 20050118 EZ - 2005/01/19 09:00 DA - 2005/02/24 09:00 DT - 2005/01/19 09:00 YR - 2004 ED - 20050223 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15655620 <573. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15457381 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kraft BM AU - Jager C AU - Kraft K AU - Leibl BJ AU - Bittner R FA - Kraft, B M FA - Jager, C FA - Kraft, K FA - Leibl, B J FA - Bittner, R IN - Kraft, B M. Department of General and Visceral Surgery, Marienhospital Stuttgart, Boheimstrasse 37, D-70199, Stuttgart, Germany. barbarakraft@vinzenz.de TI - The AESOP robot system in laparoscopic surgery: increased risk or advantage for surgeon and patient?. SO - Surgical Endoscopy. 18(8):1216-23, 2004 Aug AS - Surg Endosc. 18(8):1216-23, 2004 Aug NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Body Mass Index MH - Cholecystectomy, Laparoscopic/ae [Adverse Effects] MH - Cholecystectomy, Laparoscopic/mt [Methods] MH - *Cholecystolithiasis/su [Surgery] MH - Female MH - *Hernia, Inguinal/su [Surgery] MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy/mt [Methods] MH - Male MH - *Man-Machine Systems MH - Middle Aged MH - Prospective Studies MH - *Robotics/mt [Methods] MH - Statistics, Nonparametric MH - Time Factors MH - Treatment Outcome MH - Video-Assisted Surgery/ae [Adverse Effects] MH - *Video-Assisted Surgery/mt [Methods] AB - BACKGROUND: The aim of this study was to examine the advantages and risks of the Automated Endoscopic System for Optical Positioning (AESOP) 3000 robot system during uncomplicated laparoscopic cholecystectomies or laparoscopic hernioplasty. AB - METHODS: In a randomized study, we examined two groups of 120 patients each with the diagnosis cholecystolithiasis respectively the unilateral inguinal hernia. We worked with the AESOP 3000, a robotic arm system that is voice-controlled by the surgeon. The subjective and objective comfort of the surgeon as well as the course and length of the operation were measured. AB - RESULTS: The robot-assisted operations required significantly longer preparation and operation times. With regard to the necessary commands and manual camera corrections, the assistant group was favored. The same was true for the subjective evaluation of the surgical course by the surgeon. AB - CONCLUSIONS: Our study showed that the use of AESOP during laparoscopic cholecystectomy and hernioplasty is possible in 94% of all cases. The surgeon must accept a definite loss of comfort as well as a certain loss of time against the advantage of saving on personnel. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-003-9200-z PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial ID - 15457381 [pubmed] ID - 10.1007/s00464-003-9200-z [doi] PP - ppublish PH - 2003/07/23 [received] PH - 2004/01/15 [accepted] LG - English EP - 20040623 DP - 2004 Aug DC - 20040930 EZ - 2004/10/01 05:00 DA - 2005/02/23 09:00 DT - 2004/10/01 05:00 YR - 2004 ED - 20050222 RD - 20040930 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15457381 <574. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15657669 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - D'Annibale A AU - Morpurgo E AU - Fiscon V AU - Trevisan P AU - Sovernigo G AU - Orsini C AU - Guidolin D FA - D'Annibale, Annibale FA - Morpurgo, Emilio FA - Fiscon, Valentino FA - Trevisan, Paolo FA - Sovernigo, Gianna FA - Orsini, Camillo FA - Guidolin, Daniela IN - D'Annibale, Annibale. Divisione di Chirurgia Generale, Ospedale di Camposampiero, Padova, Italy. adannibale@tin.it TI - Robotic and laparoscopic surgery for treatment of colorectal diseases. SO - Diseases of the Colon & Rectum. 47(12):2162-8, 2004 Dec AS - Dis Colon Rectum. 47(12):2162-8, 2004 Dec NJ - Diseases of the colon and rectum PI - Journal available in: Print PI - Citation processed from: Print JC - eab, 0372764 IO - Dis. Colon Rectum SB - Index Medicus CP - United States MH - Aged MH - Blood Loss, Surgical MH - Blood Transfusion MH - Colectomy/ae [Adverse Effects] MH - Colectomy/is [Instrumentation] MH - *Colectomy/mt [Methods] MH - Colonic Diseases/su [Surgery] MH - Colonoscopy/ae [Adverse Effects] MH - *Colonoscopy/mt [Methods] MH - Female MH - Hospitals, General MH - Humans MH - Intestinal Obstruction/et [Etiology] MH - Italy MH - Length of Stay/sn [Statistics & Numerical Data] MH - Male MH - Middle Aged MH - Pneumonia/et [Etiology] MH - Proctoscopy/ae [Adverse Effects] MH - *Proctoscopy/mt [Methods] MH - Recovery of Function MH - Rectal Diseases/su [Surgery] MH - Robotics/is [Instrumentation] MH - *Robotics/mt [Methods] MH - Safety MH - Surgical Wound Infection/et [Etiology] MH - Time Factors MH - Treatment Outcome AB - PURPOSE: In the last ten years, several robotic systems have been developed to overcome the loss of the three-dimensional view and dexterity characteristic of laparoscopic surgery. The aim of this study was to compare the traditional laparoscopic approach and robotic techniques in the treatment of colorectal diseases. AB - METHODS: The study compares a consecutive series of patients treated surgically for colorectal disease from June 2001 to May 2003 with the da Vinci robotic system (Intuitive Surgical) and a matched number of patients who underwent conventional laparoscopy during the same time interval. The factors analyzed were the time required to prepare the patient and the room, total time of surgery, length of specimens, number of lymph nodes retrieved, blood loss, complications, and postoperative results. AB - RESULTS: The study included 106 patients (53 in each group). No differences were observed in total time of surgery (laparoscopic group, 222 +/- 77 minutes vs. robotic group, 240 +/- 61 minutes), specimen length (laparoscopic group, 29 +/- 11 cm vs. robotic group, 27 +/- 13 cm), or number of lymph nodes retrieved (laparoscopic group, 16 +/- 9 vs. robotic group, 17 +/- 10). It took significantly longer to prepare the operating room and patient in the robotic group (24 +/- 12 minutes) than in the laparoscopic group (18 +/- 7 minutes). There were three conversions to laparotomy in the laparoscopic group; in the robotic group, two cases were converted to laparoscopy and three to hand-assisted laparoscopy. No significant differences were observed between the two groups in terms of recovery of bowel function and postoperative hospital stay. AB - CONCLUSIONS: Robot-assisted surgery proved to be as safe and effective as laparoscopic techniques in the treatment of colorectal diseases. Because of its dexterity and three-dimensional view, the da Vinci system was particularly useful in specific stages of the procedure, e.g., takedown of the splenic flexure, dissection of a narrow pelvis, identification of nervous plexus, and handsewn anastomosis. The cost-effectiveness of the procedure still needs to be evaluated. IS - 0012-3706 IL - 0012-3706 DO - https://dx.doi.org/10.1007/s10350-004-0711-z PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 15657669 [pubmed] ID - 10.1007/s10350-004-0711-z [doi] PP - ppublish LG - English DP - 2004 Dec DC - 20050119 EZ - 2005/01/20 09:00 DA - 2005/02/04 09:00 DT - 2005/01/20 09:00 YR - 2004 ED - 20050203 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15657669 <575. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15191298 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Armato SG 3rd AU - Oxnard GR AU - MacMahon H AU - Vogelzang NJ AU - Kindler HL AU - Kocherginsky M AU - Starkey A FA - Armato, Samuel G 3rd FA - Oxnard, Geoffrey R FA - MacMahon, Heber FA - Vogelzang, Nicholas J FA - Kindler, Hedy L FA - Kocherginsky, Masha FA - Starkey, Adam IN - Armato, Samuel G 3rd. Department of Radiology, The University of Chicago, 5841 South Maryland Avenue, Chicago, Illinois 60637, USA. s-armato@uchicago.edu TI - Measurement of mesothelioma on thoracic CT scans: a comparison of manual and computer-assisted techniques. SO - Medical Physics. 31(5):1105-15, 2004 May AS - Med Phys. 31(5):1105-15, 2004 May NJ - Medical physics PI - Journal available in: Print PI - Citation processed from: Print JC - m82, 0425746 IO - Med Phys SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - *Algorithms MH - Artificial Intelligence MH - Cluster Analysis MH - Female MH - Humans MH - Information Storage and Retrieval/mt [Methods] MH - Male MH - *Mesothelioma/dg [Diagnostic Imaging] MH - Mesothelioma/pa [Pathology] MH - Middle Aged MH - Numerical Analysis, Computer-Assisted MH - *Observer Variation MH - *Pattern Recognition, Automated/mt [Methods] MH - *Pleural Neoplasms/dg [Diagnostic Imaging] MH - Pleural Neoplasms/pa [Pathology] MH - Quality Assurance, Health Care/mt [Methods] MH - Radiographic Image Enhancement/mt [Methods] MH - *Radiographic Image Interpretation, Computer-Assisted/mt [Methods] MH - *Radiography, Thoracic/mt [Methods] MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Signal Processing, Computer-Assisted AB - Our purpose in this study was to evaluate the variability of manual mesothelioma tumor thickness measurements in computed tomography (CT) scans and to assess the relative performance of six computerized measurement algorithms. The CT scans of 22 patients with malignant pleural mesothelioma were collected. In each scan, an initial observer identified up to three sites in each of three CT sections at which tumor thickness measurements were to be made. At each site, five observers manually measured tumor thickness through a computer interface. Three observers repeated these measurements during three separate sessions. Inter- and intra-observer variability in the manual measurement of tumor thickness was assessed. Six automated measurement algorithms were developed based on the geometric relationship between a specified measurement site and the automatically extracted lung regions. Computer-generated measurements were compared with manual measurements. The tumor thickness measurements of different observers were highly correlated (r > or = 0.99); however, the 95% limits of agreement for relative inter-observer difference spanned a range of 30%. Tumor thickness measurements generated by the computer algorithms also correlated highly with the average of observer measurements (r > or = 0.93). We have developed computerized techniques for the measurement of mesothelioma tumor thickness in CT scans. These techniques achieved varying levels of agreement with measurements made by human observers. IS - 0094-2405 IL - 0094-2405 DO - https://dx.doi.org/10.1118/1.1688211 PT - Clinical Trial PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Validation Studies ID - 15191298 [pubmed] ID - 10.1118/1.1688211 [doi] PP - ppublish LG - English DP - 2004 May DC - 20040611 EZ - 2004/06/12 05:00 DA - 2004/12/16 09:00 DT - 2004/06/12 05:00 YR - 2004 ED - 20041202 RD - 20170214 UP - 20170216 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=15191298 <576. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15461653 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Qayumi AK AU - Kurihara Y AU - Imai M AU - Pachev G AU - Seo H AU - Hoshino Y AU - Cheifetz R AU - Matsuura K AU - Momoi M AU - Saleem M AU - Lara-Guerra H AU - Miki Y AU - Kariya Y FA - Qayumi, A K FA - Kurihara, Y FA - Imai, M FA - Pachev, G FA - Seo, H FA - Hoshino, Y FA - Cheifetz, R FA - Matsuura, K FA - Momoi, M FA - Saleem, M FA - Lara-Guerra, H FA - Miki, Y FA - Kariya, Y IN - Qayumi, A K. Faculty of Medicine, University of British Columbia, Vancouver, British Columbia V5Z 4E3, Canada. qayumi@interchange.ubc.ca TI - Comparison of computer-assisted instruction (CAI) versus traditional textbook methods for training in abdominal examination (Japanese experience). SO - Medical Education. 38(10):1080-8, 2004 Oct AS - Med Educ. 38(10):1080-8, 2004 Oct NJ - Medical education PI - Journal available in: Print PI - Citation processed from: Print JC - mz3, 7605655 IO - Med Educ SB - Index Medicus CP - England MH - Abdomen/ph [Physiology] MH - *Clinical Competence/st [Standards] MH - *Computer-Assisted Instruction/st [Standards] MH - Curriculum MH - *Education, Medical, Undergraduate/mt [Methods] MH - Humans MH - Japan MH - *Textbooks as Topic/st [Standards] AB - PURPOSE: This study aimed to compare the effects of computer-assisted, text-based and computer-and-text learning conditions on the performances of 3 groups of medical students in the pre-clinical years of their programme, taking into account their academic achievement to date. A fourth group of students served as a control (no-study) group. AB - METHOD: Participants were recruited from the pre-clinical years of the training programmes in 2 medical schools in Japan, Jichi Medical School near Tokyo and Kochi Medical School near Osaka. Participants were randomly assigned to 4 learning conditions and tested before and after the study on their knowledge of and skill in performing an abdominal examination, in a multiple-choice test and an objective structured clinical examination (OSCE), respectively. Information about performance in the programme was collected from school records and students were classified as average, good or excellent. Student and faculty evaluations of their experience in the study were explored by means of a short evaluation survey. AB - RESULTS: Compared to the control group, all 3 study groups exhibited significant gains in performance on knowledge and performance measures. For the knowledge measure, the gains of the computer-assisted and computer-assisted plus text-based learning groups were significantly greater than the gains of the text-based learning group. The performances of the 3 groups did not differ on the OSCE measure. Analyses of gains by performance level revealed that high achieving students' learning was independent of study method. Lower achieving students performed better after using computer-based learning methods. AB - CONCLUSION: The results suggest that computer-assisted learning methods will be of greater help to students who do not find the traditional methods effective. Explorations of the factors behind this are a matter for future research. IS - 0308-0110 IL - 0308-0110 DI - MED1957 DO - https://dx.doi.org/10.1111/j.1365-2929.2004.01957.x PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 15461653 [pubmed] ID - MED1957 [pii] ID - 10.1111/j.1365-2929.2004.01957.x [doi] PP - ppublish LG - English DP - 2004 Oct DC - 20041005 EZ - 2004/10/06 09:00 DA - 2004/12/16 09:00 DT - 2004/10/06 09:00 YR - 2004 ED - 20041202 RD - 20071115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15461653 <577. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15191298 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Armato SG 3rd AU - Oxnard GR AU - MacMahon H AU - Vogelzang NJ AU - Kindler HL AU - Kocherginsky M AU - Starkey A FA - Armato, Samuel G 3rd FA - Oxnard, Geoffrey R FA - MacMahon, Heber FA - Vogelzang, Nicholas J FA - Kindler, Hedy L FA - Kocherginsky, Masha FA - Starkey, Adam IN - Armato, Samuel G 3rd. Department of Radiology, The University of Chicago, 5841 South Maryland Avenue, Chicago, Illinois 60637, USA. s-armato@uchicago.edu TI - Measurement of mesothelioma on thoracic CT scans: a comparison of manual and computer-assisted techniques. SO - Medical Physics. 31(5):1105-15, 2004 May AS - Med Phys. 31(5):1105-15, 2004 May NJ - Medical physics PI - Journal available in: Print PI - Citation processed from: Print JC - m82, 0425746 IO - Med Phys SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - *Algorithms MH - Artificial Intelligence MH - Cluster Analysis MH - Female MH - Humans MH - Information Storage and Retrieval/mt [Methods] MH - Male MH - *Mesothelioma/dg [Diagnostic Imaging] MH - Mesothelioma/pa [Pathology] MH - Middle Aged MH - Numerical Analysis, Computer-Assisted MH - *Observer Variation MH - *Pattern Recognition, Automated/mt [Methods] MH - *Pleural Neoplasms/dg [Diagnostic Imaging] MH - Pleural Neoplasms/pa [Pathology] MH - Quality Assurance, Health Care/mt [Methods] MH - Radiographic Image Enhancement/mt [Methods] MH - *Radiographic Image Interpretation, Computer-Assisted/mt [Methods] MH - *Radiography, Thoracic/mt [Methods] MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Signal Processing, Computer-Assisted AB - Our purpose in this study was to evaluate the variability of manual mesothelioma tumor thickness measurements in computed tomography (CT) scans and to assess the relative performance of six computerized measurement algorithms. The CT scans of 22 patients with malignant pleural mesothelioma were collected. In each scan, an initial observer identified up to three sites in each of three CT sections at which tumor thickness measurements were to be made. At each site, five observers manually measured tumor thickness through a computer interface. Three observers repeated these measurements during three separate sessions. Inter- and intra-observer variability in the manual measurement of tumor thickness was assessed. Six automated measurement algorithms were developed based on the geometric relationship between a specified measurement site and the automatically extracted lung regions. Computer-generated measurements were compared with manual measurements. The tumor thickness measurements of different observers were highly correlated (r > or = 0.99); however, the 95% limits of agreement for relative inter-observer difference spanned a range of 30%. Tumor thickness measurements generated by the computer algorithms also correlated highly with the average of observer measurements (r > or = 0.93). We have developed computerized techniques for the measurement of mesothelioma tumor thickness in CT scans. These techniques achieved varying levels of agreement with measurements made by human observers. IS - 0094-2405 IL - 0094-2405 DO - https://dx.doi.org/10.1118/1.1688211 PT - Clinical Trial PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Validation Studies ID - 15191298 [pubmed] ID - 10.1118/1.1688211 [doi] PP - ppublish LG - English DP - 2004 May DC - 20040611 EZ - 2004/06/12 05:00 DA - 2004/12/16 09:00 DT - 2004/06/12 05:00 YR - 2004 ED - 20041202 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15191298 <578. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15498362 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Chen SL AU - Fang WW AU - Qian J AU - Ye F AU - Liu YH AU - Shan SJ AU - Zhang JJ AU - Lin S AU - Liao LM AU - Zhao RC FA - Chen, Shao-liang FA - Fang, Wu-wang FA - Qian, Jun FA - Ye, Fei FA - Liu, Yu-hao FA - Shan, Shou-jie FA - Zhang, Jun-jie FA - Lin, Song FA - Liao, Lian-ming FA - Zhao, Robert Chun Hua IN - Chen, Shao-liang. Department of Cardiology, Nanjing First Municipal Hospital, Nanjing Medical University, Nanjing 210006, China. chmengx@126.com TI - Improvement of cardiac function after transplantation of autologous bone marrow mesenchymal stem cells in patients with acute myocardial infarction.[Erratum appears in Chin Med J (Engl). 2005 Jan 5;118(1):88] SO - Chinese Medical Journal. 117(10):1443-8, 2004 Oct AS - Chin Med J. 117(10):1443-8, 2004 Oct NJ - Chinese medical journal PI - Journal available in: Print PI - Citation processed from: Print JC - 0005256, d3b, 7513795 IO - Chin. Med. J. SB - Index Medicus CP - China MH - Adult MH - Aged MH - *Bone Marrow Cells/cy [Cytology] MH - Female MH - Humans MH - Male MH - Mesenchymal Stem Cell Transplantation MH - Mesenchymal Stromal Cells/cy [Cytology] MH - Middle Aged MH - *Myocardial Infarction/th [Therapy] MH - Tomography, Emission-Computed, Single-Photon MH - Transplantation, Autologous AB - BACKGROUND: The infarct size determines the long-term prognosis of patients with acute myocardial infarction (AMI). There is a growing interest in repairing scar area by transplanting bone marrow stem cells. However, effectiveness of intracoronary injection of bone marrow mesenchymal stem cells (BMSCs) in patients with AMI still remains unclear. AB - METHODS: Sixty-nine patients with AMI after percutaneous coronary intervention (PCI) were randomly divided into intracoronary injection of BMSCs (n = 34) and saline (control group, n = 35) groups. Serial single positron emission computer tomography (SPECT), cardiac echo and cardiac electromechanical mapping were done at the designed time intervals until six months after transplantation of BMSCs or injection of saline. AB - RESULTS: The proportion with functional defect decreased significantly in the BMSCs patients after three months [(13 +/- 5)%] compared with that pre-transplantation [(32 +/- 11)%] and the control group [(28 +/- 10)%] at three month follow-up (P < 0.05, respectively). Wall movement velocity over the infracted region increased significantly in the BMSCs group [(4.2 +/- 2.5) cm/s vs (2.2 +/- 1.3) cm/s, P < 0.05], but not in the control group [(2.2 +/- 1.5) cm/s vs (2.7 +/- 1.7) cm/s, P > 0.05]. Left ventricular ejection fraction (LVEF) three months after transplantation in BMSCs group increased significantly compared with that pre-implantation and with that of the control group at three months post-injection [(67 +/- 11)% vs (49 +/- 9)% and (53 +/- 8)%, P < 0.05 respectively]. SPECT scan results showed that perfusion defect was improved significantly in BMSCs group at three-month follow-up compared with that in the control group [(134 +/- 66) cm(2) vs (185 +/- 87) cm(2), P < 0.01]. At the same time, left ventricular end-diastolic volume [(136 +/- 31) ml vs (162 +/- 27) ml, P < 0.05] and end-systolic volume [(63 +/- 20) ml vs (88 +/- 19) ml, P < 0.05] decreased synchronously. The ratio of end-systolic pressure to end-systolic volume [Psyst/ESV, (2.84 +/- 1.30) mmHg/ml vs (1.72 +/- 1.23) mmHg/ml, P < 0.05] increased significantly. Cardiac electromechanical mapping demonstrated significant improvement at three months after implantation of BMSCs compared with that pre-injection in both cardiac mechanical capability as left line local shorting [LLS, (11.29 +/- 1.64)% vs (7.32 +/- 1.86)%, P < 0.05] and electrical property as left ventricular endocardial unipolar voltage [UV, (10.38 +/- 1.12) mV vs (7.61 +/- 1.09) mV, P < 0.01]; perfusion defect decreased from (36.2 +/- 6.2)% to (20.3 +/- 5.31)% (P < 0.01). Twenty-four-hour electrocardiographic monitoring demonstrated no arrhythmias occurred at three-months follow-up. AB - CONCLUSIONS: The transplantation of BMSCs might improve the cardiac function and it is safe and feasible with no deaths or malignant arrhythmias. IS - 0366-6999 IL - 0366-6999 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial ID - 15498362 [pubmed] PP - ppublish LG - English DP - 2004 Oct DC - 20041022 EZ - 2004/10/23 09:00 DA - 2004/12/16 09:00 DT - 2004/10/23 09:00 YR - 2004 ED - 20041130 RD - 20121115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15498362 <579. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15146302 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ekins-Daukes S AU - Helms PJ AU - Simpson CR AU - Taylor MW AU - McLay JS FA - Ekins-Daukes, Suzie FA - Helms, Peter J FA - Simpson, Colin R FA - Taylor, Michael W FA - McLay, James S IN - Ekins-Daukes, Suzie. Department of Medicine and Therapeutics, The University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen AB25 2ZD, Scotland, UK. TI - Off-label prescribing to children in primary care: retrospective observational study. SO - European Journal of Clinical Pharmacology. 60(5):349-53, 2004 Jul AS - Eur J Clin Pharmacol. 60(5):349-53, 2004 Jul NJ - European journal of clinical pharmacology PI - Journal available in: Print-Electronic PI - Citation processed from: Print JC - en4, 1256165 IO - Eur. J. Clin. Pharmacol. SB - Index Medicus CP - Germany MH - Adolescent MH - *Anti-Bacterial Agents/ad [Administration & Dosage] MH - *Anti-Inflammatory Agents, Non-Steroidal/ad [Administration & Dosage] MH - Chemistry, Pharmaceutical MH - Child MH - Child, Preschool MH - Drug Labeling MH - Humans MH - Infant MH - Infant, Newborn MH - Licensure MH - Medical Records Systems, Computerized MH - *Practice Patterns, Physicians' MH - *Primary Health Care MH - Retrospective Studies MH - Scotland AB - OBJECTIVES: To investigate the extent and pattern of off-label prescribing to children in primary care throughout Scotland. AB - DESIGN: Assessment of prescribing to 167,865 children aged 0-16 years during the period November 1999 to October 2000 using data from 161 general practices using the national Scottish primary care computer system General Practice Administration System for Scotland. AB - SETTING: One hundred and sixty one general practices in Scotland. AB - RESULTS: During the study period, at least one off-label prescription was issued to 17,715 (26.1%) children aged 0-16 years. Off-label prescribing due to lower than the recommended dose was the most common form of off-label prescribing (40-50%), with antibiotics and antihistamines making up the majority. Off-label prescribing due to higher than the recommended dose was also common (35% of all off-label prescribing), with antiasthmatics, topical corticosteroids and laxatives making up the majority. Off-label prescribing with respect to age was less common (6-16%) affecting mainly young children (less than 2 years old) and adolescents. Off-label prescribing with respect to formulation was the least common cause accounting for 5-10% of off-label prescribing. AB - CONCLUSIONS: This is the largest and most detailed study to date of paediatric off-label prescribing in primary care within the UK. Such off-label prescribing likely occurs as the result of several factors including a failure to update licensing information with currently accepted practice and confusion or unawareness of the licensing recommendations, further compounded by a lack of clinical trials data and suitable formulations for medicines commonly prescribed to young children and adolescents. RN - 0 (Anti-Bacterial Agents) RN - 0 (Anti-Inflammatory Agents, Non-Steroidal) IS - 0031-6970 IL - 0031-6970 DO - https://dx.doi.org/10.1007/s00228-004-0752-1 PT - Journal Article ID - 15146302 [pubmed] ID - 10.1007/s00228-004-0752-1 [doi] PP - ppublish PH - 2003/12/05 [received] PH - 2004/02/16 [accepted] LG - English EP - 20040514 DP - 2004 Jul DC - 20040804 EZ - 2004/05/18 05:00 DA - 2004/11/09 09:00 DT - 2004/05/18 05:00 YR - 2004 ED - 20041108 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15146302 <580. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15216868 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Meininger D AU - Byhahn C AU - Wolfram M AU - Mierdl S AU - Kessler P AU - Westphal K FA - Meininger, D FA - Byhahn, C FA - Wolfram, M FA - Mierdl, S FA - Kessler, P FA - Westphal, K IN - Meininger, D. Department of Anesthesiology, Intensive Care Medicine and Pain Control, J.W. Goethe-University Hospital, Theodor-Stern-Kai 7, D-60590 Frankfurt, Germany. dirk_meininger@gmx.de TI - Prolonged intraperitoneal versus extraperitoneal insufflation of carbon dioxide in patients undergoing totally endoscopic robot-assisted radical prostatectomy. SO - Surgical Endoscopy. 18(5):829-33, 2004 May AS - Surg Endosc. 18(5):829-33, 2004 May NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Aged MH - Carbon Dioxide/ad [Administration & Dosage] MH - *Endoscopy MH - Hemodynamics MH - Humans MH - *Insufflation/mt [Methods] MH - Male MH - Middle Aged MH - Peritoneal Cavity MH - Prospective Studies MH - Respiration MH - *Robotics MH - *Transurethral Resection of Prostate/mt [Methods] AB - BACKGROUND: Extraperitoneal laparoscopic prostatectomy is an alternative to the intraperitoneal method. However, the effects of extraperitoneal carbon dioxide (CO2) insufflation on hemodynamics and respiratory data have not been adequately studied. This study compared the effects of prolonged intra- and extraperitoneal CO2 insufflation on hemodynamics and gas exchange. AB - METHODS: For this study, 20 patients were assigned to receive totally endoscopic robot-assisted radical prostatectomy (TERP) via the intra- or extraperitoneal approach. Hemodynamic parameters and respiratory data were obtained during 8 h of insufflation and analyzed for statistical differences. AB - RESULTS: With both insufflation methods, arterial CO2 pressure increased rapidly, reaching higher levels with extraperitoneal insufflation. Therefore, patients managed with extraperitoneal insufflation required a significantly higher minute ventilation. Heart rate and central venous pressure increased in both groups, whereas mean arterial blood pressure and pH decreased. AB - CONCLUSIONS: Prolonged intra- and extraperitoneal CO2 insufflation for TERP resulted in significant, but mostly clinically unimportant, hemodynamic alterations. Carbon dioxide absorption was more pronounced with extraperitoneal insufflation. RN - 142M471B3J (Carbon Dioxide) ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-003-9086-9 PT - Clinical Trial PT - Journal Article ID - 15216868 [pubmed] ID - 10.1007/s00464-003-9086-9 [doi] PP - ppublish PH - 2003/03/28 [received] PH - 2003/11/21 [accepted] LG - English EP - 20040406 DP - 2004 May DC - 20040624 EZ - 2004/06/26 05:00 DA - 2004/10/22 09:00 DT - 2004/06/26 05:00 YR - 2004 ED - 20041020 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15216868 <581. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15005306 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Maeda H FA - Maeda, Hisatoshi IN - Maeda, Hisatoshi. Department of Radiological Technology, School of Health Sciences, Nagoya University, 1-1-20 DaikoMinami, Higashi-ku, Nagoya, Japan. maeda@met.nagoya-u.ac.jp TI - Quantification of synchronous contraction of left ventricle in normal subjects using ECG-gated-SPECT images. SO - Physiological Measurement. 25(1):71-84, 2004 Feb AS - Physiol Meas. 25(1):71-84, 2004 Feb NJ - Physiological measurement PI - Journal available in: Print PI - Citation processed from: Print JC - bn5, 9306921 IO - Physiol Meas SB - Index Medicus CP - England MH - Adult MH - *Electrocardiography MH - Female MH - *Heart Diseases/dg [Diagnostic Imaging] MH - Heart Diseases/pp [Physiopathology] MH - Humans MH - Male MH - Middle Aged MH - Models, Cardiovascular MH - *Myocardial Contraction/ph [Physiology] MH - *Tomography, Emission-Computed, Single-Photon/mt [Methods] MH - *Ventricular Function, Left/ph [Physiology] AB - Intact heart muscles are believed to contract synchronously to produce maximum effective work at a minimum energy cost. Temporal correlation coefficients between the left ventricular volume and muscle contraction were introduced to assess the synchronicity of left ventricular contraction (synchronous contraction index, SCI), and applied to eight normal volunteers. Area-contraction and length-shortening parallel to and perpendicular to the long axis were computed from electrocardiogram (ECG)-gated single-photon emission computed tomographies (SPECT) using a homemade computer programme. The cardiac wall was divided into nine segments, and the average values of accumulation of perfusion agents, amplitude of contraction and SCI were obtained in each segment. The area-SCI was 91.4% +/- 4.3% and relatively uniform over the whole cardiac wall (p = 0.014, analysis of variance (ANOVA)), whereas the accumulation and amplitude of contraction varied significantly in different segments (p < 0.0001, ANOVA). This study suggested that in normal subjects the myocardial contraction was synchronous, and that the amplitude of contraction was not spatially uniform. IS - 0967-3334 IL - 0967-3334 PT - Clinical Trial PT - Journal Article ID - 15005306 [pubmed] PP - ppublish LG - English DP - 2004 Feb DC - 20040309 EZ - 2004/03/10 05:00 DA - 2004/09/29 05:00 DT - 2004/03/10 05:00 YR - 2004 ED - 20040928 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15005306 <582. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 14716538 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Nio D AU - Bemelman WA AU - Busch OR AU - Vrouenraets BC AU - Gouma DJ FA - Nio, D FA - Bemelman, W A FA - Busch, O R C FA - Vrouenraets, B C FA - Gouma, D J IN - Nio, D. Department of Surgery, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. TI - Robot-assisted laparoscopic cholecystectomy versus conventional laparoscopic cholecystectomy: a comparative study. SO - Surgical Endoscopy. 18(3):379-82, 2004 Mar AS - Surg Endosc. 18(3):379-82, 2004 Mar NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adult MH - *Cholecystectomy, Laparoscopic/is [Instrumentation] MH - Elective Surgical Procedures/sn [Statistics & Numerical Data] MH - Equipment Design MH - Female MH - Humans MH - Intraoperative Period MH - Male MH - *Man-Machine Systems MH - Middle Aged MH - Robotics/is [Instrumentation] MH - *Robotics MH - Time and Motion Studies AB - BACKGROUND: The efficacy of conventional laparoscopic cholecystectomy (CLC) was compared with robot-assisted laparoscopic cholecystectomy (RLC). Surgical trainees performed the LC to avoid the surgeon's experience bias. AB - METHODS: Two surgical trainees performed 10 CLCs and 10 RLCs at random with a Zeus-Aesop Surgical Robotic System. The primary efficacy parameters were the total time and the number of actions involved in the procedure. The secondary parameters were setup and dissection times, and the number of grasping and dissection actions. Surgical complications were evaluated. AB - RESULTS: For CLC and RLC, respectively, the total times were 95.4 +/- 28 min and 123.5 +/- 33.3 min and the total actions were 420 +/- 176.3 and 363.5 +/- 158.2. For CLC, the times required for setup (21 +/- 10.4 min) and dissection (50.2 +/- 17.7 min) were less than for RLC (33.8 +/- 11.3 min and 72 +/- 24.3 min, respectively). The numbers of grasping and dissection actions were not significantly different: 41.4 +/- 26.5 and 378 +/- 173.7, respectively, for CLC versus 48.9 +/- 27 and 314.6 +/- 141.9, respectively, for RLC. AB - CONCLUSION: Although feasible, RLC requires significantly more time than CLC because of slower performed actions. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s00464-003-9133-6 PT - Clinical Trial PT - Comparative Study PT - Controlled Clinical Trial PT - Evaluation Studies PT - Journal Article ID - 14716538 [pubmed] ID - 10.1007/s00464-003-9133-6 [doi] PP - ppublish PH - 2003/05/26 [received] PH - 2003/09/02 [accepted] LG - English EP - 20040114 DP - 2004 Mar DC - 20040421 EZ - 2004/01/13 05:00 DA - 2004/08/26 05:00 DT - 2004/01/13 05:00 YR - 2004 ED - 20040825 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=14716538 <583. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15257478 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Marmulla R AU - Muhling J AU - Wirtz CR AU - Hassfeld S FA - Marmulla, R FA - Muhling, J FA - Wirtz, C R FA - Hassfeld, S IN - Marmulla, R. Department of Cranio-Maxillofacial Surgery, University of Heidelberg, Heidelberg, Germany. Ruediger_Marmulla@med.uni-heidelberg.de TI - High-resolution laser surface scanning for patient registration in cranial computer-assisted surgery. SO - Minimally Invasive Neurosurgery. 47(2):72-8, 2004 Apr AS - Minim Invasive Neurosurg. 47(2):72-8, 2004 Apr NJ - Minimally invasive neurosurgery : MIN PI - Journal available in: Print PI - Citation processed from: Print JC - b54, 9440973 IO - Minim Invasive Neurosurg SB - Index Medicus CP - Germany MH - *Brain Diseases/su [Surgery] MH - Data Collection MH - Face/ah [Anatomy & Histology] MH - Humans MH - *Lasers MH - *Neurosurgical Procedures/mt [Methods] MH - *Patient Identification Systems/mt [Methods] MH - Reference Values MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Skin MH - *Skull/ah [Anatomy & Histology] MH - *Skull/su [Surgery] MH - *Surgery, Computer-Assisted/mt [Methods] AB - OBJECTIVE: Markerless patient registration is a new procedure that may reduce logistical efforts and possibly also the radiation load on the patients prior to a computer-assisted intervention. Congruent surfaces, such as bone surfaces or skin surfaces, represented in a data set and in the surgical site, can be overlapped using surface-matching. Previous studies describing this kind of markerless registration, however, show inaccuracies of up to 10 mm during computer-assisted navigation. Furthermore, these systems use less than 1000 surface points of the soft tissue surface in order to establish a correlation between the patient and the data set. Previous papers did not answer the question whether it is this scanning resolution that induces these inaccuracies in registration or rather intraoperative skin deformations. AB - STUDY DESIGN: In the present study therefore a new navigation system (SSN++) was used which is able to register up to 180,000 surface points of the surgical site. SSN++ is an infrared navigation system enlarged by a Minolta VI 900 3D volume digitizer. Three different kinds of laser scan-resolution were used for data correlation. An additional congruence analysis was performed in order to assess the geometry of the matched skin surfaces. 22 patients suffering from different cranial diseases (tumors, bony malformations, foreign bodies) were prepared for a computer-assisted intervention. Intraoral titanium-markers, rigidly fixed on the patients by a maxillary splint, were placed as targets while the CT data sets were made. These targets were - after markerless laser scan registration of the patients - supposed to serve for validating the new high-resolution navigation system SSN++. AB - RESULTS: The accuracy of markerless laser scan registration depends on the intraoperative laser scan's resolution. A high accuracy of the data correlation can be achieved if the number of the laser scan cloud points is about the same as the number of voxels of the corresponding surface on the CT data set. A reduction of the laser scan cloud points to less than 10 % compared to the number of voxels of the CT surface, however, leads to a significant loss of accuracy after markerless patient registration. AB - CONCLUSION: The markerless laser scan registration of the surgical site may achieve the same accuracy as a patient registration made by rigidly fixed titanium screws (mean accuracy: 1.2 mm) as long as a high-resolution laser scan is being used. IS - 0946-7211 IL - 0946-7211 DO - https://dx.doi.org/10.1055/s-2004-818471 PT - Clinical Trial PT - Journal Article ID - 15257478 [pubmed] ID - 10.1055/s-2004-818471 [doi] PP - ppublish LG - English DP - 2004 Apr DC - 20040716 EZ - 2004/07/17 05:00 DA - 2004/08/25 05:00 DT - 2004/07/17 05:00 YR - 2004 ED - 20040824 RD - 20041117 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15257478 <584. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15100929 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Wong GK AU - Poon WS AU - Ng SC AU - Cheng AY FA - Wong, G K FA - Poon, W S FA - Ng, S C FA - Cheng, A Y IN - Wong, G K. Division of Neurosurgery, Department of Surgery Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong. TI - Fluoroscopic frameless computer-assisted navigation for transsphenoidal surgery: a clinical assessment of accuracy in spatial position and trajectory. SO - Minimally Invasive Neurosurgery. 47(1):29-31, 2004 Feb AS - Minim Invasive Neurosurg. 47(1):29-31, 2004 Feb NJ - Minimally invasive neurosurgery : MIN PI - Journal available in: Print PI - Citation processed from: Print JC - b54, 9440973 IO - Minim Invasive Neurosurg SB - Index Medicus CP - Germany MH - *Adenoma/dg [Diagnostic Imaging] MH - *Adenoma/su [Surgery] MH - Fluoroscopy MH - Humans MH - *Neuronavigation/mt [Methods] MH - *Pituitary Neoplasms/dg [Diagnostic Imaging] MH - *Pituitary Neoplasms/su [Surgery] MH - Reproducibility of Results MH - Sphenoid Bone/dg [Diagnostic Imaging] MH - *Sphenoid Bone/su [Surgery] MH - *Surgery, Computer-Assisted/mt [Methods] AB - OBJECTIVE: Fluoroscopic navigation technique in transsphenoidal surgery on the one hand provides multi-planar (antero-posterior and lateral views) navigation while on the other hand it does not need any preoperative preparation. To assess the clinical accuracy of the above technique in the transsphenoidal surgery, we performed this study. AB - METHODS: 5 patients undergoing transsphenoidal surgery were assessed. Fluoroscopic images were compared with C-arm X-ray images for difference in spatial position and trajectory. AB - RESULTS: 26 sets of data were collected for analysis. Mean pointer tip difference was 0.6 mm. The 95 % confidence interval was 1.3 mm. Mean trajectory difference was 1.2 degree. The 95 % confidence interval was 2.7 degree. AB - CONCLUSION: With a good clinical accuracy, fluoroscopic navigation offers a distinct advantage to replace the traditional fluoroscopic approach for transsphenoidal surgery for its low X-ray exposure and multi-planar (antero-posterior and lateral views) navigation. IS - 0946-7211 IL - 0946-7211 DO - https://dx.doi.org/10.1055/s-2003-812535 PT - Clinical Trial PT - Journal Article ID - 15100929 [pubmed] ID - 10.1055/s-2003-812535 [doi] PP - ppublish LG - English DP - 2004 Feb DC - 20040421 EZ - 2004/04/22 05:00 DA - 2004/07/23 05:00 DT - 2004/04/22 05:00 YR - 2004 ED - 20040722 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15100929 <585. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 14604249 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sobieski MA 2nd AU - Slaughter MS AU - Hart DE AU - Pappas PS AU - Tatooles AJ FA - Sobieski, Michael A 2nd FA - Slaughter, Mark S FA - Hart, David E FA - Pappas, Patroklos S FA - Tatooles, Antone J IN - Sobieski, Michael A 2nd. Division of Cardiac Surgery, Christ Hospital and Medical Center, Oak Lawn, IL, USA. TI - Peripheral cardiopulmonary bypass with modified assisted venous drainage and transthoracic aortic crossclamp: optimal management for robotic mitral valve repair. SO - Perfusion. 18(5):307-11, 2003 Sep AS - Perfusion. 18(5):307-11, 2003 Sep NJ - Perfusion PI - Journal available in: Print PI - Citation processed from: Print JC - bdd, 8700166 IO - Perfusion SB - Index Medicus CP - England MH - Adult MH - Aged MH - Aged, 80 and over MH - Cardiac Surgical Procedures/mt [Methods] MH - Cardiac Surgical Procedures/st [Standards] MH - *Cardiopulmonary Bypass/mt [Methods] MH - *Drainage/mt [Methods] MH - Equipment Design MH - Female MH - Humans MH - Length of Stay MH - Male MH - Middle Aged MH - *Mitral Valve/su [Surgery] MH - Postoperative Complications MH - *Robotics MH - Surgical Instruments MH - Time AB - The purpose of this study was to evaluate peripheral cardiopulmonary bypass (CPB) with modified assisted venous drainage (MAVD) and transthoracic aortic cross-clamping to maintain a bloodless surgical field, adequate myocardial protection, systemic flow and pressure during robotic surgical repair of the mitral valve. Peripheral CPB was established with a standard Duraflo-coated closed circuit with femoral arterial and venous cannulation. An additional 17 Fr wire-bound cannula was inserted into the right internal jugular vein and drainage rates of 200-400 mL/min were regulated using a separate roller-head pump. A transthoracic aortic crossclamp with antegrade cardioplegia was used for myocardial protection. Mitral valve (MV) repair was then performed through two 1-cm ports for the robotic arms and a 4-cm intercostal incision for the camera and passing suture. From October 2001 to October 2002, 25 patients underwent robotic MV repair. Average surgical times include leaflet resection and repair, 20 min, and insertion of annuloplasty ring, 28 min; average perfusion times, crossclamp 88 min and total bypass time of 126 min. There were no incisional conversions, no reoperations for bleeding and no deaths, strokes or perioperative myocardial infarctions. Twenty-one (84%) patients were extubated in the operating room. Average LOS was 2.7 days with eight (32%) patients discharged home in less than 24 hours. In conclusion, peripheral CPB with gravity drainage of the lower body and MAVD of the upper body allow safe and effective support during robotically assisted minimally invasive MV repair. This approach may be applied to other forms of minimally invasive cardiac surgery that requires CPB. IS - 0267-6591 IL - 0267-6591 DO - https://dx.doi.org/10.1191/0267659103pf682oa PT - Clinical Trial PT - Clinical Trial, Phase II PT - Journal Article PT - Multicenter Study ID - 14604249 [pubmed] ID - 10.1191/0267659103pf682oa [doi] PP - ppublish LG - English DP - 2003 Sep DC - 20031107 EZ - 2003/11/08 05:00 DA - 2004/07/14 05:00 DT - 2003/11/08 05:00 YR - 2003 ED - 20040713 RD - 20170214 UP - 20170215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=14604249 <586. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 14604249 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sobieski MA 2nd AU - Slaughter MS AU - Hart DE AU - Pappas PS AU - Tatooles AJ FA - Sobieski, Michael A 2nd FA - Slaughter, Mark S FA - Hart, David E FA - Pappas, Patroklos S FA - Tatooles, Antone J IN - Sobieski, Michael A 2nd. Division of Cardiac Surgery, Christ Hospital and Medical Center, Oak Lawn, IL, USA. TI - Peripheral cardiopulmonary bypass with modified assisted venous drainage and transthoracic aortic crossclamp: optimal management for robotic mitral valve repair. SO - Perfusion. 18(5):307-11, 2003 Sep AS - Perfusion. 18(5):307-11, 2003 Sep NJ - Perfusion PI - Journal available in: Print PI - Citation processed from: Print JC - bdd, 8700166 IO - Perfusion SB - Index Medicus CP - England MH - Adult MH - Aged MH - Aged, 80 and over MH - Cardiac Surgical Procedures/mt [Methods] MH - Cardiac Surgical Procedures/st [Standards] MH - *Cardiopulmonary Bypass/mt [Methods] MH - *Drainage/mt [Methods] MH - Equipment Design MH - Female MH - Humans MH - Length of Stay MH - Male MH - Middle Aged MH - *Mitral Valve/su [Surgery] MH - Postoperative Complications MH - *Robotics MH - Surgical Instruments MH - Time AB - The purpose of this study was to evaluate peripheral cardiopulmonary bypass (CPB) with modified assisted venous drainage (MAVD) and transthoracic aortic cross-clamping to maintain a bloodless surgical field, adequate myocardial protection, systemic flow and pressure during robotic surgical repair of the mitral valve. Peripheral CPB was established with a standard Duraflo-coated closed circuit with femoral arterial and venous cannulation. An additional 17 Fr wire-bound cannula was inserted into the right internal jugular vein and drainage rates of 200-400 mL/min were regulated using a separate roller-head pump. A transthoracic aortic crossclamp with antegrade cardioplegia was used for myocardial protection. Mitral valve (MV) repair was then performed through two 1-cm ports for the robotic arms and a 4-cm intercostal incision for the camera and passing suture. From October 2001 to October 2002, 25 patients underwent robotic MV repair. Average surgical times include leaflet resection and repair, 20 min, and insertion of annuloplasty ring, 28 min; average perfusion times, crossclamp 88 min and total bypass time of 126 min. There were no incisional conversions, no reoperations for bleeding and no deaths, strokes or perioperative myocardial infarctions. Twenty-one (84%) patients were extubated in the operating room. Average LOS was 2.7 days with eight (32%) patients discharged home in less than 24 hours. In conclusion, peripheral CPB with gravity drainage of the lower body and MAVD of the upper body allow safe and effective support during robotically assisted minimally invasive MV repair. This approach may be applied to other forms of minimally invasive cardiac surgery that requires CPB. IS - 0267-6591 IL - 0267-6591 PT - Clinical Trial PT - Clinical Trial, Phase II PT - Journal Article PT - Multicenter Study ID - 14604249 [pubmed] PP - ppublish LG - English DP - 2003 Sep DC - 20031107 EZ - 2003/11/08 05:00 DA - 2004/07/14 05:00 DT - 2003/11/08 05:00 YR - 2003 ED - 20040713 RD - 20041117 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=14604249 <587. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15172249 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tatooles AJ AU - Pappas PS AU - Gordon PJ AU - Slaughter MS FA - Tatooles, Antone J FA - Pappas, Patroklos S FA - Gordon, Paul J FA - Slaughter, Mark S IN - Tatooles, Antone J. Division of Cardiac Surgery, Advocate Christ Medical Center, Oak Lawn, Illinois, USA. TI - Minimally invasive mitral valve repair using the da Vinci robotic system. SO - Annals of Thoracic Surgery. 77(6):1978-82; discussion 1982-4, 2004 Jun AS - Ann Thorac Surg. 77(6):1978-82; discussion 1982-4, 2004 Jun NJ - The Annals of thoracic surgery PI - Journal available in: Print PI - Citation processed from: Print JC - 683, 15030100r IO - Ann. Thorac. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - Netherlands MH - Adult MH - Aged MH - Aged, 80 and over MH - Female MH - Humans MH - Length of Stay MH - Male MH - Middle Aged MH - Minimally Invasive Surgical Procedures MH - *Mitral Valve/su [Surgery] MH - Mitral Valve Insufficiency/su [Surgery] MH - Postoperative Complications MH - Reoperation MH - *Robotics AB - BACKGROUND: Minimally invasive mitral valve repair with a shortened hospital stay and quick return to an active lifestyle is the ultimate goal for robotically assisted surgery. We evaluated our da Vinci robotically assisted mitral valve repair experience toward achieving this goal. AB - METHODS: All procedures were performed with peripheral cardiopulmonary bypass, transthoracic aortic cross-clamp, and antegrade cardioplegia. Two ports and a 4-cm intercostal incision in the right chest were used for access. All patients had a ring annuloplasty, and all but 1 had a posterior leaflet resection. The entire repair and all knot tying were performed robotically. AB - RESULTS: Between October 2001 and October 2002, 25 patients (18 men) underwent robotic mitral valve repair. The mean age was 56 years (range, 37 to 81 years). There were no incisional conversions, deaths, strokes, or reoperations for bleeding. Twenty-one (84%) of 25 patients were extubated in the operating room. Overall mean study times were as follows: procedure, 199.7 minutes (range, 140 to 287 minutes); cardiopulmonary bypass, 126.6 minutes (range, 89 to 186 minutes); and cross-clamp, 87.7 minutes (range, 58 to 143 minutes). Eight (32%) patients were discharged home in less than 24 hours, with an average length of stay of 2.7 days. Comparing the first 10 patients to the last 15 there was a significant reduction of times: total operating room time, 318.5 versus 275.1 minutes; cross-clamp, 97.6 versus 81.1 minutes; leaflet resection or repair, 26.2 versus 15.6 minutes; annuloplasty ring, 31.9 versus 24.8 minutes; and length of stay, from 4.2 days to 1.67 days. Five patients had postoperative atrial fibrillation. Two (8%) patients ultimately required mitral valve replacement for recurrent mitral insufficiency. AB - CONCLUSIONS: Mitral valve repair can be successfully performed with the da Vinci robotic system. Long-term follow-up is needed to determine the durability of the repair compared with a standard sternotomy approach. IS - 0003-4975 IL - 0003-4975 DI - S000349750400027X DO - https://dx.doi.org/10.1016/j.athoracsur.2003.11.024 PT - Clinical Trial PT - Clinical Trial, Phase II PT - Journal Article PT - Multicenter Study ID - 15172249 [pubmed] ID - 10.1016/j.athoracsur.2003.11.024 [doi] ID - S000349750400027X [pii] PP - ppublish PH - 2003/11/25 [accepted] LG - English DP - 2004 Jun DC - 20040602 EZ - 2004/06/03 05:00 DA - 2004/06/30 05:00 DT - 2004/06/03 05:00 YR - 2004 ED - 20040629 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15172249 <588. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15011864 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Zeng ZC AU - Tang ZY AU - Yang BH AU - Fan J AU - Qin LX AU - Jiang GL AU - Zhou J AU - Sun HC AU - Cheng JM AU - Wang JH FA - Zeng, Zhao-Chong FA - Tang, Zhao-You FA - Yang, Bing-Hui FA - Fan, Jia FA - Qin, Lun-Xiu FA - Jiang, Guo-Liang FA - Zhou, Jian FA - Sun, Hui-Chuan FA - Cheng, Jie-Min FA - Wang, Jian-Hua IN - Zeng, Zhao-Chong. Department of Radiation Oncology, Zhongshan Hospital, Fudan University, Shanghai, China. Zengzhaochong@yahoo.com TI - Radiation therapy for the locoregional lymph node metastases from hepatocellular carcinoma, phase I clinical trial. SO - Hepato-Gastroenterology. 51(55):201-7, 2004 Jan-Feb AS - Hepatogastroenterology. 51(55):201-7, 2004 Jan-Feb NJ - Hepato-gastroenterology PI - Journal available in: Print PI - Citation processed from: Print JC - 8007849, ga7 IO - Hepatogastroenterology SB - Index Medicus CP - Greece MH - Adult MH - Aged MH - Carcinoma, Hepatocellular/dg [Diagnostic Imaging] MH - *Carcinoma, Hepatocellular/sc [Secondary] MH - Female MH - Humans MH - Liver Neoplasms/dg [Diagnostic Imaging] MH - *Liver Neoplasms/pa [Pathology] MH - Lymphatic Metastasis MH - Male MH - Middle Aged MH - Radiography MH - Radiotherapy Dosage AB - BACKGROUND/AIMS: The patients with lymph node metastasis from hepatocellular carcinoma may survive only a few months. These patients are not suitable for transcatheter arterial chemoembolization, percutaneous ethanol injection and surgical resection. External beam radiation therapy (EBRT) could provide a useful treatment, but only 4 hepatocellular carcinoma cases with abdominal lymph nodes involvement were treated with EBRT in the two reports over the last 10 years. In this paper, we report 29 hepatocellular carcinoma patients with abdominal lymph node metastasis who received EBRT over a period of 5 years. AB - METHODOLOGY: Of 29 patients, 20 were pathologically confirmed to have hepatocellular carcinoma and 9 patients were clinically diagnosed to have hepatocellular carcinoma. All of the patients had proven abdominal lymph node metastasis by enhanced abdominal computer tomography scan due to clinical follow-up or abdominal symptoms. EBRT was not the initial treatment in all. The patients received locoregional lymph nodes irradiation. The tumor dose ranged from 30 to 60 Grays (Gy) in daily 2.0-Gy fractions (Fx), 5 times a week. AB - RESULTS: It is of interest to note that an objective regression (complete response and partial response) rate was 100%. The clinical symptoms were relieved. The median survival time was 8 (4-28) months. The overall 1-year and 2-year survival rates were 43.5% and 10.5%, respectively. The median survival time consistently decreased as the lymph node involvement increase follows the natural flow of lymph. AB - CONCLUSIONS: Lymph node metastasis from hepatocellular carcinoma is sensitive to EBRT, although EBRT is palliative in intent, it is useful in the treatment with 50 Gy/25 Fx for those patients. IS - 0172-6390 IL - 0172-6390 PT - Clinical Trial PT - Clinical Trial, Phase I PT - Journal Article ID - 15011864 [pubmed] PP - ppublish LG - English DP - 2004 Jan-Feb DC - 20040311 EZ - 2004/03/12 05:00 DA - 2004/06/21 10:00 DT - 2004/03/12 05:00 YR - 2004 ED - 20040608 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15011864 <589. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 14648044 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Omejc M AU - Mekicar J FA - Omejc, Mirko FA - Mekicar, Jernej IN - Omejc, Mirko. Department of Abdominal Surgery, University Medical Center, Zaloska 7, 1525 Ljubljana, Slovenia. mirko.omejc@mf.uni-lj.si TI - Role of computer analysis in gastric cancer surgery: evaluation of the WinEstimate v. 2.5 computer program. SO - World Journal of Surgery. 28(1):59-62, 2004 Jan AS - World J Surg. 28(1):59-62, 2004 Jan NJ - World journal of surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Print JC - xo8, 7704052 IO - World J Surg SB - Index Medicus CP - United States MH - Female MH - Humans MH - *Lymphatic Metastasis MH - Male MH - Middle Aged MH - Predictive Value of Tests MH - Reproducibility of Results MH - *Stomach Neoplasms/pa [Pathology] MH - *Stomach Neoplasms/su [Surgery] AB - To identify the group of patients with gastric cancer who can benefit from extensive lymphadenectomy and to offer a rational approach to lymph node dissection, it is important to know the incidence of metastases at each lymph node station. A computer program was developed for assessment of lymph node involvement and survival time in each individual case according to preoperative variables. In patients who have undergone R0 resection with D2 lymphadenectomy, differences between the individual results generated by the computer and the actual data were compared. A cutoff point of 10% in the prediction of metastases was used as a positive result. The computer program made false predictions in 9% of patients for the pN status (3% lower and 6% higher than the actual status). Computerized prediction of 5-year survival was close to the rate calculated by the Kaplan-Meier method (55.5% vs 56.1%). Preoperative computer analysis of patient data and tumor characteristics offers a rational approach to individualizing tumor therapy] where the extent of lymph node dissection is tailored to the type, site, and stage of the tumor, thereby minimizing the disadvantages (morbidity, mortality) associated with the extensive operative procedure. IS - 0364-2313 IL - 0364-2313 DO - https://dx.doi.org/10.1007/s00268-003-7007-7 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 14648044 [pubmed] ID - 10.1007/s00268-003-7007-7 [doi] PP - ppublish LG - English EP - 20031205 DP - 2004 Jan DC - 20040119 EZ - 2003/12/03 05:00 DA - 2004/06/02 05:00 DT - 2003/12/03 05:00 YR - 2004 ED - 20040601 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=14648044 <590. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 15017273 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Schiff J AU - Li PS AU - Goldstein M FA - Schiff, Jonathan FA - Li, Philip S FA - Goldstein, Marc IN - Schiff, Jonathan. Department of Urology and Center for Male Reproductive Medicine and Microsurgery, Cornell Institute for Reproductive Medicine, New York, New York, USA. TI - Robotic microsurgical vasovasostomy and vasoepididymostomy: a prospective randomized study in a rat model. SO - Journal of Urology. 171(4):1720-5, 2004 Apr AS - J Urol. 171(4):1720-5, 2004 Apr NJ - The Journal of urology PI - Journal available in: Print PI - Citation processed from: Print JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Animals MH - *Epididymis/su [Surgery] MH - Male MH - *Microsurgery/is [Instrumentation] MH - *Microsurgery/mt [Methods] MH - Prospective Studies MH - Random Allocation MH - Rats MH - Rats, Wistar MH - *Robotics MH - *Vasovasostomy/is [Instrumentation] MH - *Vasovasostomy/mt [Methods] AB - PURPOSE: Microsurgical vasovasostomy and vasoepididymostomy remain technically challenging procedures. Refinements in technique have continually improved patency and pregnancy rates for the 2 procedures in experienced hands. Advances in surgical robotics produced the Da Vinci robot (Intuitive Surgical, Inc., Sunnyvale, California) with motion reduction and no tremor, features that may improve outcomes in microsurgery. We report a randomized prospective study of vasoepididymostomy and vasovasostomy using the Da Vinci robot in rats. AB - MATERIALS AND METHODS: A total of 24 adult male Wistar rats underwent vasectomy through a midline abdominal incision. Two weeks later the animals were randomized to microsurgical multilayer vasovasostomy, longitudinal vasoepididymostomy or robotic vasovasostomy and vasoepididymostomy groups. Outcomes measured included surgical time, complications, patency and sperm granuloma formation at 9 weeks. AB - RESULTS: Animals were sacrificed 9 weeks after microsurgery. There were no significant differences in complications among the groups. Robotic vasovasostomy was significantly faster than the conventional microsurgical technique (68.5 vs 102.5 minutes, p = 0.002). The robotic and microsurgical vasoepididymostomy groups did not differ significantly in time. Patency rates were 100% for the robotic vasovasostomy and vasoepididymostomy groups, and 90% in the microsurgical vasovasostomy and vasoepididymostomy groups. These differences were not significant. Sperm granulomas were found in 70% of microsurgical vasovasostomy anastomoses and 27% of robotic vasovasostomy anastomoses (p = 0.001). No significant difference in the sperm granuloma rate was found between the robotic or microsurgical vasoepididymostomy groups (42% and 50%, respectively, p = 0.37). AB - CONCLUSIONS: To our knowledge we report the first randomized prospective study using the Da Vinci robot for microsurgery. We believe that the improved stability and motion reduction during microsurgical suturing with the robot helped achieve excellent patency rates for vasovasostomy and vasoepididymostomy. The robot may also allow experienced microsurgeons to perform microsurgical procedures in patients at remote locations where no experienced microsurgeons are available. IS - 0022-5347 IL - 0022-5347 DI - S0022-5347(05)62396-8 DO - https://dx.doi.org/10.1097/01.ju.0000115902.00988.68 PT - Journal Article ID - 15017273 [pubmed] ID - S0022-5347(05)62396-8 [pii] ID - 10.1097/01.ju.0000115902.00988.68 [doi] PP - ppublish LG - English DP - 2004 Apr DC - 20040312 EZ - 2004/03/17 05:00 DA - 2004/05/07 05:00 DT - 2004/03/17 05:00 YR - 2004 ED - 20040505 RD - 20040312 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=15017273 <591. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 14687254 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tierney WM AU - Overhage JM AU - Murray MD AU - Harris LE AU - Zhou XH AU - Eckert GJ AU - Smith FE AU - Nienaber N AU - McDonald CJ AU - Wolinsky FD FA - Tierney, William M FA - Overhage, J Marc FA - Murray, Michael D FA - Harris, Lisa E FA - Zhou, Xiao-Hua FA - Eckert, George J FA - Smith, Faye E FA - Nienaber, Nancy FA - McDonald, Clement J FA - Wolinsky, Fredric D IN - Tierney, William M. Regenstrief Institute for Health Care, Indiana University School of Medicine, Indianapolis, Indiana, USA. wtierney@iupui.edu TI - Effects of computerized guidelines for managing heart disease in primary care. CM - Comment in: J Gen Intern Med. 2003 Dec;18(12):1060-1; PMID: 14687267 SO - Journal of General Internal Medicine. 18(12):967-76, 2003 Dec AS - J Gen Intern Med. 18(12):967-76, 2003 Dec NJ - Journal of general internal medicine PI - Journal available in: Print PI - Citation processed from: Print JC - jgi, 8605834 IO - J Gen Intern Med PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1494965 SB - Index Medicus CP - United States MH - Algorithms MH - *Decision Making, Computer-Assisted MH - Female MH - Guideline Adherence MH - *Heart Failure/th [Therapy] MH - Hospital Information Systems MH - Humans MH - Logistic Models MH - Male MH - Medical Records Systems, Computerized MH - Microcomputers MH - Middle Aged MH - *Myocardial Ischemia/th [Therapy] MH - Outcome Assessment (Health Care) MH - Poisson Distribution MH - *Practice Guidelines as Topic MH - Primary Health Care MH - *Quality Assurance, Health Care MH - United States MH - United States Agency for Healthcare Research and Quality AB - BACKGROUND: Electronic information systems have been proposed as one means to reduce medical errors of commission (doing the wrong thing) and omission (not providing indicated care). AB - OBJECTIVE: To assess the effects of computer-based cardiac care suggestions. AB - DESIGN: A randomized, controlled trial targeting primary care physicians and pharmacists. AB - SUBJECTS: A total of 706 outpatients with heart failure and/or ischemic heart disease. AB - INTERVENTIONS: Evidence-based cardiac care suggestions, approved by a panel of local cardiologists and general internists, were displayed to physicians and pharmacists as they cared for enrolled patients. AB - MEASUREMENTS: Adherence with the care suggestions, generic and condition-specific quality of life, acute exacerbations of their cardiac disease, medication compliance, health care costs, satisfaction with care, and physicians' attitudes toward guidelines. AB - RESULTS: Subjects were followed for 1 year during which they made 3,419 primary care visits and were eligible for 2,609 separate cardiac care suggestions. The intervention had no effect on physicians' adherence to the care suggestions (23% for intervention patients vs 22% for controls). There were no intervention-control differences in quality of life, medication compliance, health care utilization, costs, or satisfaction with care. Physicians viewed guidelines as providing helpful information but constraining their practice and not helpful in making decisions for individual patients. AB - CONCLUSIONS: Care suggestions generated by a sophisticated electronic medical record system failed to improve adherence to accepted practice guidelines or outcomes for patients with heart disease. Future studies must weigh the benefits and costs of different (and perhaps more Draconian) methods of affecting clinician behavior. IS - 0884-8734 IL - 0884-8734 DI - 30635 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, U.S. Gov't, P.H.S. ID - 14687254 [pubmed] ID - 30635 [pii] ID - PMC1494965 [pmc] PP - ppublish GI - No: 1R01-HS07763 Organization: (HS) *AHRQ HHS* Country: United States LG - English DP - 2003 Dec DC - 20031222 EZ - 2003/12/23 05:00 DA - 2004/05/05 05:00 DT - 2003/12/23 05:00 YR - 2003 ED - 20040504 RD - 20161019 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=14687254 <592. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 14745222 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Varma TR AU - Eldridge PR AU - Forster A AU - Fox S AU - Fletcher N AU - Steiger M AU - Littlechild P AU - Byrne P AU - Sinnott A AU - Tyler K AU - Flintham S FA - Varma, T R K FA - Eldridge, P R FA - Forster, A FA - Fox, S FA - Fletcher, N FA - Steiger, M FA - Littlechild, P FA - Byrne, P FA - Sinnott, A FA - Tyler, K FA - Flintham, S IN - Varma, T R K. Walton Centre for Neurology and Neurosurgery, Liverpool, UK. tv.varma@thewaltoncentre.nhs.uk TI - Use of the NeuroMate stereotactic robot in a frameless mode for movement disorder surgery. SO - Stereotactic & Functional Neurosurgery. 80(1-4):132-5, 2003 AS - Stereotact Funct Neurosurg. 80(1-4):132-5, 2003 NJ - Stereotactic and functional neurosurgery PI - Journal available in: Print PI - Citation processed from: Print JC - sfn, 8902881 IO - Stereotact Funct Neurosurg SB - Index Medicus CP - Switzerland MH - Humans MH - Magnetic Resonance Imaging MH - *Movement Disorders/su [Surgery] MH - Neurosurgical Procedures MH - *Robotics MH - *Stereotaxic Techniques/is [Instrumentation] MH - Surgery, Computer-Assisted AB - BACKGROUND/AIMS: To evaluate the use of the NeuroMate stereotactic robot with a novel ultrasound registration system for movement disorder surgery (MDS). AB - METHODS: Using the robot in a frameless mode, 51 patients underwent MDS. Surgical planning was carried out using MRI data obtained more than 24 h before surgery. AB - RESULTS: 37 out of 50 targets in the subthalamic nucleus were satisfactorily identified with a single microelectrode trajectory and the final electrode positions were at a mean distance of 1.7 mm from the calculated target. There was a significant improvement in motor scores of the Unified Parkinson's Disease Rating Scale III (off medication) at 6 (43%) and 18 months (51.7%) compared to pre-operative scores (p < 0.05). AB - CONCLUSIONS: The frameless robot using only MRI data can be used for MDS. The temporal separation of imaging from the surgical procedure provides additional time for detailed image analysis and planning. AB - Copyright 2003 S. Karger AG, Basel IS - 1011-6125 IL - 1011-6125 DI - 75173 DO - https://dx.doi.org/75173 PT - Clinical Trial PT - Journal Article ID - 14745222 [pubmed] ID - 75173 [doi] ID - 75173 [pii] PP - ppublish LG - English DP - 2003 DC - 20040127 EZ - 2004/01/28 05:00 DA - 2004/04/02 05:00 DT - 2004/01/28 05:00 YR - 2003 ED - 20040401 RD - 20041117 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=14745222 <593. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 14702997 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - van der Linden D AU - Frese M AU - Sonnentag S FA - van der Linden, Dimitri FA - Frese, Michael FA - Sonnentag, Sabine IN - van der Linden, Dimitri. Department of Work and Organizational Psychology, University of Nijmegen, P.O. Box 9104, 6500 HE Nijmegen, Netherlands. d.vanderlinden@psych.kun.nl TI - The impact of mental fatigue on exploration in a complex computer task: rigidity and loss of systematic strategies. SO - Human Factors. 45(3):483-94, 2003 Fall AS - Hum Factors. 45(3):483-94, 2003 Fall NJ - Human factors PI - Journal available in: Print PI - Citation processed from: Print JC - ge5, 0374660 IO - Hum Factors SB - Index Medicus SB - National Aeronautics and Space Administration (NASA) Journals CP - United States MH - Adult MH - *Attention/ph [Physiology] MH - *Computers MH - Female MH - Humans MH - Male MH - Man-Machine Systems MH - *Mental Fatigue/pp [Physiopathology] MH - Pattern Recognition, Visual MH - Problem Solving MH - Reaction Time MH - *Task Performance and Analysis AB - We investigated the impact of mental fatigue on exploration in a complex computer task. The exploration behavior of participants who underwent a fatigue manipulation (N = 36) was compared with that of a control (nonfatigued) group (N = 32). A distinction was also made between participants with high or low levels of general computer experience. Results showed that fatigued participants used significantly less systematic exploration and made more errors than did nonfatigued participants. Fatigued participants with low computer experience also showed significantly more rigid behavior than did the other participants. No differences were found on the number of subtasks solved. Compared with low-experience participants, highly experienced participants showed significantly more systematic exploration, less unsystematic trial and error, solved more subtasks, and made fewer errors (marginally significant p = .056). Findings were interpreted as the result of reduced task engagement under fatigue and reduced involvement of executive control on behavior. Actual or potential applications of this research include guidelines to prevent detrimental effects of mental fatigue on exploration behavior. IS - 0018-7208 IL - 0018-7208 DO - https://dx.doi.org/10.1518/hfes.45.3.483.27256 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 14702997 [pubmed] ID - 10.1518/hfes.45.3.483.27256 [doi] PP - ppublish LG - English DP - 2003 Fall DC - 20040101 EZ - 2004/01/02 05:00 DA - 2004/02/11 05:00 DT - 2004/01/02 05:00 YR - 2003 ED - 20040209 RD - 20170214 UP - 20170215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=14702997 <594. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 14702997 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - van der Linden D AU - Frese M AU - Sonnentag S FA - van der Linden, Dimitri FA - Frese, Michael FA - Sonnentag, Sabine IN - van der Linden, Dimitri. Department of Work and Organizational Psychology, University of Nijmegen, P.O. Box 9104, 6500 HE Nijmegen, Netherlands. d.vanderlinden@psych.kun.nl TI - The impact of mental fatigue on exploration in a complex computer task: rigidity and loss of systematic strategies. SO - Human Factors. 45(3):483-94, 2003 Fall AS - Hum Factors. 45(3):483-94, 2003 Fall NJ - Human factors PI - Journal available in: Print PI - Citation processed from: Print JC - ge5, 0374660 IO - Hum Factors SB - Index Medicus SB - National Aeronautics and Space Administration (NASA) Journals CP - United States MH - Adult MH - *Attention/ph [Physiology] MH - *Computers MH - Female MH - Humans MH - Male MH - Man-Machine Systems MH - *Mental Fatigue/pp [Physiopathology] MH - Pattern Recognition, Visual MH - Problem Solving MH - Reaction Time MH - *Task Performance and Analysis AB - We investigated the impact of mental fatigue on exploration in a complex computer task. The exploration behavior of participants who underwent a fatigue manipulation (N = 36) was compared with that of a control (nonfatigued) group (N = 32). A distinction was also made between participants with high or low levels of general computer experience. Results showed that fatigued participants used significantly less systematic exploration and made more errors than did nonfatigued participants. Fatigued participants with low computer experience also showed significantly more rigid behavior than did the other participants. No differences were found on the number of subtasks solved. Compared with low-experience participants, highly experienced participants showed significantly more systematic exploration, less unsystematic trial and error, solved more subtasks, and made fewer errors (marginally significant p = .056). Findings were interpreted as the result of reduced task engagement under fatigue and reduced involvement of executive control on behavior. Actual or potential applications of this research include guidelines to prevent detrimental effects of mental fatigue on exploration behavior. IS - 0018-7208 IL - 0018-7208 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 14702997 [pubmed] PP - ppublish LG - English DP - 2003 Fall DC - 20040101 EZ - 2004/01/02 05:00 DA - 2004/02/11 05:00 DT - 2004/01/02 05:00 YR - 2003 ED - 20040209 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=14702997 <595. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 14613088 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Theodossy T AU - Bamber MA FA - Theodossy, Tamer FA - Bamber, Mohammad Anwar IN - Theodossy, Tamer. Oral and Maxillofacial Surgery, University College London Hospitals NHS Trust, Mortimer Market, London WC1E 6AU, UK. tamertheodossy@hotmail.com TI - Model surgery with a passive robot arm for orthognathic surgery planning. SO - Journal of Oral & Maxillofacial Surgery. 61(11):1310-7, 2003 Nov AS - J Oral Maxillofac Surg. 61(11):1310-7, 2003 Nov NJ - Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons PI - Journal available in: Print PI - Citation processed from: Print JC - jic, 8206428 IO - J. Oral Maxillofac. Surg. SB - Core Clinical Journals (AIM) SB - Dental Journals SB - Index Medicus CP - United States MH - Cephalometry MH - Dental Articulators MH - Dental Models MH - Equipment Design MH - Humans MH - Jaw Relation Record MH - *Maxilla/su [Surgery] MH - *Models, Anatomic MH - *Patient Care Planning MH - *Robotics/is [Instrumentation] MH - Statistics, Nonparametric AB - PURPOSE: The aims of the study were to assess the degree of accuracy of model surgery performed manually using the Eastman technique and to compare it with model surgery performed with the aid of a robot arm. AB - PATIENTS AND METHODS: Twenty-one patients undergoing orthognathic surgery gave consent for this study. They were divided into 2 groups based on the model surgery technique used. Group A (52%) had model surgery performed manually, whereas group B (48%) had their model surgery performed using the robot arm. Patients' maxillary casts were measured before and after model surgery, and results were compared with those for the original treatment plan in horizontal (x-axis), vertical (y-axis), and transverse (z-axis) planes. AB - RESULTS: Statistical analysis using Mann-Whitney U test for x- and y-axis and independent sample t test for z-axis have shown significant differences between both groups in x-axis (P =.024) and y-axis (P =.01) but not in z-axis (P =.776). AB - CONCLUSIONS: Model surgery performed with the aid of a robot arm is significantly more accurate in anteroposterior and vertical planes than is manual model surgery. Robot arm has an important role to play in orthognathic surgery planning and in determining the biometrics of orthognathic surgical change at the model surgery stage. IS - 0278-2391 IL - 0278-2391 DI - S027823910300733X PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 14613088 [pubmed] ID - S027823910300733X [pii] PP - ppublish LG - English DP - 2003 Nov DC - 20031112 EZ - 2003/11/13 05:00 DA - 2003/12/12 05:00 DT - 2003/11/13 05:00 YR - 2003 ED - 20031210 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=14613088 <596. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 12875935 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bentas W AU - Wolfram M AU - Jones J AU - Brautigam R AU - Kramer W AU - Binder J FA - Bentas, Wassilios FA - Wolfram, Marc FA - Jones, Jon FA - Brautigam, Ronald FA - Kramer, Wolfgang FA - Binder, Jochen IN - Bentas, Wassilios. Department of Urology and Pediatric Urology, J.W. Goethe University of Frankfurt, University Hospital Frankfurt am Main, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany. bentas@em.uni-frankfurt.de TI - Robotic technology and the translation of open radical prostatectomy to laparoscopy: the early Frankfurt experience with robotic radical prostatectomy and one year follow-up. SO - European Urology. 44(2):175-81, 2003 Aug AS - Eur Urol. 44(2):175-81, 2003 Aug NJ - European urology PI - Journal available in: Print PI - Citation processed from: Print JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland MH - Aged MH - Blood Loss, Surgical MH - Epigastric Arteries/in [Injuries] MH - Erectile Dysfunction/et [Etiology] MH - Follow-Up Studies MH - Hemostasis, Surgical MH - Humans MH - Laparoscopy/ae [Adverse Effects] MH - *Laparoscopy/mt [Methods] MH - Length of Stay MH - Male MH - Middle Aged MH - Obturator Nerve/in [Injuries] MH - Outcome and Process Assessment (Health Care) MH - Postoperative Complications MH - Prostate-Specific Antigen/bl [Blood] MH - Prostatectomy/ae [Adverse Effects] MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/bl [Blood] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/su [Surgery] MH - Pulmonary Embolism/et [Etiology] MH - *Robotics/mt [Methods] MH - Time Factors MH - Urinary Incontinence/et [Etiology] MH - Urinary Tract Infections/et [Etiology] MH - Venous Thrombosis/et [Etiology] AB - OBJECTIVE: Laparoscopic radical prostatectomy is a complex procedure and has been standardized only during the last years. The remote controlled da Vinci Surgical System has opened up a new era in minimally invasive surgery. We here present our initial experience with the translation of open retropubic radical prostatectomy to laparoscopic technique using da Vinci and a one year follow-up. AB - METHODS: After a period of technical development and training on cadavers, 40 consecutive patients eligible for radical prostatectomy were treated. After port placement, the urologist took control of the 3D 30 degrees laparoscope and the two instrument arms at the da Vinci remote console to perform bilateral pelvic lymph node dissection, radical prostatovesiculectomy and urethrovesical anastomosis. AB - RESULTS: The procedure was completed laparoscopically in all but two patients. Mean procedure time was 8.3 hours and mean intra-operative blood loss 570 ml. Learning curves associated with the use of the da Vinci Surgical System show that there is a 22-minute decrease in time required to perform the radical prostatectomy and lymphadenectomy for each case (p<0.0001). Patients recovered rapidly after surgery with early oncological and functional results that were similar to those obtained with our standard radical prostatectomy technique. AB - CONCLUSIONS: Remote controlled robotic surgical systems are useful to translate open retropubic radical prostatectomy to laparoscopy. This new technology has the potential to equip the urologist with the microsurgical precision needed to preserve the delicate structural integrity of the pelvic floor in order to improve functional results without compromising the oncological outcome. RN - EC 3-4-21-77 (Prostate-Specific Antigen) IS - 0302-2838 IL - 0302-2838 DI - S0302283803002562 PT - Clinical Trial PT - Journal Article ID - 12875935 [pubmed] ID - S0302283803002562 [pii] PP - ppublish LG - English DP - 2003 Aug DC - 20030723 EZ - 2003/07/24 05:00 DA - 2003/12/12 05:00 DT - 2003/07/24 05:00 YR - 2003 ED - 20031210 RD - 20071115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=12875935 <597. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 12879833 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Davey R AU - Edwards SM AU - Cochrane T FA - Davey, Rachel FA - Edwards, Sarah Matthes FA - Cochrane, Tom IN - Davey, Rachel. Department of Sport, Health and Exercise, School of Health, Staffordshire University, Leek Road, Stoke on Trent ST4 2DF. r.davey@staffs.ac.uk TI - Recruitment strategies for a clinical trial of community-based water therapy for osteoarthritis. SO - British Journal of General Practice. 53(489):315-7, 2003 Apr AS - Br J Gen Pract. 53(489):315-7, 2003 Apr NJ - The British journal of general practice : the journal of the Royal College of General Practitioners PI - Journal available in: Print PI - Citation processed from: Print JC - 9005323, ark IO - Br J Gen Pract PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1314575 SB - Index Medicus CP - England MH - Advertising as Topic MH - Aged MH - Databases, Factual MH - Family Practice MH - Female MH - Humans MH - *Hydrotherapy MH - Leg MH - Male MH - *Osteoarthritis/th [Therapy] MH - *Patient Selection MH - *Randomized Controlled Trials as Topic/mt [Methods] AB - This study compares the efficiency of two methods of recruitment into a randomised controlled trial examining the cost-effectiveness of water therapy for elderly people with lower limb osteoarthritis. The direct cost of recruiting patients via general practice was 27.66 Pounds per patient (1.1 personnel hours/patient). The cost per recruited patient from a local newspaper article was 2.72 Pounds (0.2 personnel hours/patient). The cost differential between the two recruitment methods was largely owing to poor administration practices, difficulties in accessing patient information, and difficulties in contacting patients from the general practice computer database. IS - 0960-1643 IL - 0960-1643 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 12879833 [pubmed] ID - PMC1314575 [pmc] PP - ppublish LG - English DP - 2003 Apr DC - 20030725 EZ - 2003/07/26 05:00 DA - 2003/10/04 05:00 DT - 2003/07/26 05:00 YR - 2003 ED - 20031003 RD - 20140611 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=12879833 <598. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 12970231 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Argenziano M AU - Oz MC AU - Kohmoto T AU - Morgan J AU - Dimitui J AU - Mongero L AU - Beck J AU - Smith CR FA - Argenziano, Michael FA - Oz, Mehmet C FA - Kohmoto, Takushi FA - Morgan, Jeffrey FA - Dimitui, Jaina FA - Mongero, Linda FA - Beck, James FA - Smith, Craig R IN - Argenziano, Michael. Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York, NY, USA. ma66@columbia.edu TI - Totally endoscopic atrial septal defect repair with robotic assistance. SO - Circulation. 108 Suppl 1:II191-4, 2003 Sep 09 AS - Circulation. 108 Suppl 1:II191-4, 2003 Sep 09 NJ - Circulation PI - Journal available in: Print PI - Citation processed from: Internet JC - daw, 0147763 IO - Circulation SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Catheterization/is [Instrumentation] MH - *Endoscopy MH - Female MH - Heart Septal Defects, Atrial/di [Diagnosis] MH - *Heart Septal Defects, Atrial/su [Surgery] MH - Humans MH - Male MH - Middle Aged MH - Postoperative Complications MH - Robotics/is [Instrumentation] MH - *Robotics MH - Treatment Outcome AB - BACKGROUND: Computer (robotic) enhancement had emerged as a facilitator of minimally invasive cardiac surgery, and has been used to perform portions of intracardiac procedures via thoracotomy incisions. This report describes the next step in this progression-the first U.S. application of robotic technology for totally endoscopic open heart surgery. AB - METHODS AND RESULTS: Seventeen patients underwent repair of a secundum-type atrial septal defect (n=12) or patent foramen ovale (n=5) by a totally endoscopic approach, utilizing the Da Vinci robotic system. Cardiopulmonary bypass (CPB) was achieved peripherally. Cardioplegia was administered via the distal port of the arterial cannula after endo-balloon inflation. Via three port incisions in the right chest, pericardiotomy, bicaval occlusion, atriotomy, atrial septopexy, and atrial closure were performed by a surgeon seated at a computer console. A fourth 15-mm port was utilized for suction and suture passage by a patient-side assistant. The mean age of the patients was 47 years (range, 22 to 68). Aortic crossclamp time was 32 minutes (median), and CPB time was 122 minutes. In 16 patients, transesophageal echocardiography after 30 days confirmed successful repair. In one patient, a recurrent shunt was identified and repaired on postoperative day 5. Median length of stay (LOS) in the intensive care unit was 20 hours, and median hospital length of stay was 4 days. AB - CONCLUSIONS: Robotic technology can be utilized to perform open heart procedures safely and effectively via totally endoscopic approaches. This technique represents an option for patients seeking a reliable ASD repair but wishing to avoid sternotomy or thoracotomy. ES - 1524-4539 IL - 0009-7322 DI - 108/10_suppl_1/II-191 DO - https://dx.doi.org/10.1161/01.cir.0000089043.82199.2f PT - Clinical Trial PT - Journal Article ID - 12970231 [pubmed] ID - 10.1161/01.cir.0000089043.82199.2f [doi] ID - 108/10_suppl_1/II-191 [pii] PP - ppublish LG - English DP - 2003 Sep 09 DC - 20030912 EZ - 2003/09/13 05:00 DA - 2003/10/01 05:00 DT - 2003/09/13 05:00 YR - 2003 ED - 20030930 RD - 20041117 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=12970231 <599. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 12400817 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Stahl KD AU - Boyd WD AU - Vassiliades TA AU - Karamanoukian HL FA - Stahl, Kenneth D FA - Boyd, W Douglas FA - Vassiliades, Thomas A FA - Karamanoukian, Hratch L IN - Stahl, Kenneth D. Section of Thoracic and Cardiovascular Surgery, Cleveland Clinic Florida, Weston 33331, USA. stahlk@ccf.org TI - Hybrid robotic coronary artery surgery and angioplasty in multivessel coronary artery disease. SO - Annals of Thoracic Surgery. 74(4):S1358-62, 2002 Oct AS - Ann Thorac Surg. 74(4):S1358-62, 2002 Oct NJ - The Annals of thoracic surgery PI - Journal available in: Print PI - Citation processed from: Print JC - 683, 15030100r IO - Ann. Thorac. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - Netherlands MH - Adult MH - Aged MH - Aged, 80 and over MH - *Angioplasty, Balloon, Coronary MH - *Coronary Disease/th [Therapy] MH - Erythrocyte Transfusion MH - Female MH - Follow-Up Studies MH - Humans MH - Intensive Care Units MH - Length of Stay MH - Male MH - Middle Aged MH - *Myocardial Revascularization MH - Postoperative Complications MH - Postpericardiotomy Syndrome/et [Etiology] MH - *Robotics MH - Stents/ae [Adverse Effects] MH - *Thoracoscopy MH - Thoracotomy AB - BACKGROUND: Complete surgical revascularization that includes left internal thoracic artery grafting to the left anterior descending coronary artery remains the gold standard of treatment for coronary artery disease. Not all patients are good candidates for sternotomy. Therefore, we sought to identify a strategy that would combine the long-term advantages of internal thoracic artery grafting to lessen surgical trauma while still allowing complete revascularization. AB - METHODS: A total of 54 consecutive patients from four institutions underwent hybrid revascularization combining surgery and angioplasty. All internal thoracic artery grafts were endoscopically harvested with robotic assistance using either the Aesop or Zeus system, and all anastomoses were manually constructed through a 4- to 6-cm anterior thoracotomy incision. Angioplasty was carried out to achieve total revascularization to ungrafted vessels. AB - RESULTS: There were no early or late deaths, myocardial infarctions, strokes, or wound infections. Of the patients, 37 (69%) were extubated in the operating room. Length of stay in the intensive care unit averaged 24.4 hours and hospital stay 3.45 days. In all, 16 patients (29.6%) required transfusion of packed red blood cells. Late complications included 1 patient with stent occlusion at 3 months and 2 patients with in-stent restenosis. Three patients were treated for postpericardiotomy syndrome. Mean follow-up was 11.7 months. Event-free was survival 87.1% and freedom from recurrent angina 98.3%. AB - CONCLUSIONS: Hybrid endoscopic atraumatic internal thoracic artery to anterior descending coronary artery graft surgery combined with angioplasty is a reasonable revascularization strategy in multiple vessel coronary artery disease in selected patients. Longer follow-up and more patient data in a randomized study are needed to determine the patient cohort most likely to benefit from this approach. IS - 0003-4975 IL - 0003-4975 PT - Clinical Trial PT - Journal Article PT - Multicenter Study ID - 12400817 [pubmed] PP - ppublish LG - English DP - 2002 Oct DC - 20021028 EZ - 2002/10/29 04:00 DA - 2002/11/28 04:00 DT - 2002/10/29 04:00 YR - 2002 ED - 20021126 RD - 20101118 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=12400817 <600. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 12400812 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Cisowski M AU - Drzewiecki J AU - Drzewiecka-Gerber A AU - Jaklik A AU - Kruczak W AU - Szczeklik M AU - Bochenek A FA - Cisowski, Marek FA - Drzewiecki, Janusz FA - Drzewiecka-Gerber, Agnieszka FA - Jaklik, Andrzej FA - Kruczak, Wojciech FA - Szczeklik, Michal FA - Bochenek, Andrzej IN - Cisowski, Marek. First Department of Cardiac Surgery, Medical University of Silesia, Katowice, Poland. marek.cisowski@cardiosurg.pl TI - Primary stenting versus MIDCAB: preliminary report-comparision of two methods of revascularization in single left anterior descending coronary artery stenosis. SO - Annals of Thoracic Surgery. 74(4):S1334-9, 2002 Oct AS - Ann Thorac Surg. 74(4):S1334-9, 2002 Oct NJ - The Annals of thoracic surgery PI - Journal available in: Print PI - Citation processed from: Print JC - 683, 15030100r IO - Ann. Thorac. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - Netherlands MH - Coronary Angiography MH - Coronary Restenosis MH - *Coronary Stenosis/su [Surgery] MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Postoperative Complications MH - *Stents MH - *Thoracoscopy AB - BACKGROUND: Percutaneous revascularization is a well-accepted method of treatment for a single left anterior descending coronary artery (LAD) stenosis. With the introduction of primary stenting, it has become the treatment of choice for a LAD lesion. In the last few years however, the introduction of minimally invasive cardiac surgery, video-assisted left internal thoracic artery (LITA) harvesting, and robotic surgery have raised the question as to whether minimally invasive surgical revascularization would be competitive with percutaneous coronary interventions in cases of single-vessel stenoses. AB - METHODS: A group of 100 patients with Canadian Cardiovascular Society class II to IV, and angiographically confirmed single critical stenosis of the LAD (type A or B), were treated with direct primary stenting (group 1, n = 50), or with endoscopic atraumatic coronary artery bypass grafting (group 2, n =50). AB - RESULTS: All patients in a group 1, obtained a very good angiographic and clinical effect. No acute postoperative complications were noted at 1 month of follow-up. However, at 1 month of follow-up, 3 patients (6%) developed restenosis of the LAD, and at 6 months follow-up, 6 patients (12%), developed restenosis of the LAD. In these cases, repeated percutaneous coronary interventions of the target vessel were successfully performed. In group 2, very good operative results were observed. In 1 and 6 months of follow-up, all patients remained asymptomatic. Critical stenosis of the left internal thoracic artery-LAD anastomosis was angiographically documented in 1 case (2%). This patient was successfully treated with balloon angioplasty. AB - CONCLUSIONS: The study results document the superiority of endoscopic atraumatic coronary artery bypass grafting over direct primary stenting in LAD revascularization, along with the slightly higher costs of the surgical procedure. IS - 0003-4975 IL - 0003-4975 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 12400812 [pubmed] PP - ppublish LG - English DP - 2002 Oct DC - 20021028 EZ - 2002/10/29 04:00 DA - 2002/11/28 04:00 DT - 2002/10/29 04:00 YR - 2002 ED - 20021126 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=12400812 <601. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 12028390 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - McDonough M AU - Marks IM FA - McDonough, Michael FA - Marks, Isaac M IN - McDonough, Michael. Maudsley Hospital, London, UK. spbpmdm@iop.kcl.uk.com TI - Teaching medical students exposure therapy for phobia/panic - randomized, controlled comparison of face-to-face tutorial in small groups vs. solo computer instruction. SO - Medical Education. 36(5):412-7, 2002 May AS - Med Educ. 36(5):412-7, 2002 May NJ - Medical education PI - Journal available in: Print PI - Citation processed from: Print JC - mz3, 7605655 IO - Med Educ SB - Index Medicus CP - England MH - *Computer-Assisted Instruction/mt [Methods] MH - Curriculum MH - *Education, Medical, Undergraduate/mt [Methods] MH - England MH - Female MH - Humans MH - Male MH - *Phobic Disorders/th [Therapy] MH - *Psychotherapy/ed [Education] MH - *Teaching/mt [Methods] AB - OBJECTIVE: To compare the teaching value of one session of computer-guided solo instruction in exposure therapy for phobias with that of one face-to-face small-group tutorial. AB - DESIGN: Non-blind, randomized, controlled study. AB - SETTING: King's College Hospital Medical School, London. AB - PARTICIPANTS: Thirty-seven third-year medical students and 11 behaviour therapists. AB - MAIN OUTCOME MEASURES: Seventy-five true/false multiple choice questions relating to (b) below answered at pre- and post-teaching by students and just once by behaviour therapists to obtain 'expert' scores; pre- and post-teaching ratings of interest in behaviour therapy and post-teaching ratings of educational and enjoyment value. EDUCATIONAL INTERVENTIONS: (a) All students had a 20-minute group lecture on basic concepts and historical aspects just before randomization to: (b) 90 min of either solo computer or group face-to-face tutorial teaching. Computer instruction used a short version of 'FearFighter'- a self-help computer system for people suffering from phobias. AB - RESULTS: Solo computer instruction taught exposure therapy principles effectively but improved multiple choice question scores marginally less than did small-group tutorial teaching. Tutorial teaching required 5 times more teacher time but led to knowledge scores that did not differ significantly from those of behaviour therapists. Students clearly rated face-to-face small-group tutorial teaching as more enjoyable. AB - CONCLUSION: The knowledge gain from a solo computer session resembled that from a small-group face-to-face tutorial, and required far less teacher time, but was less enjoyable. Enjoyment might rise if the computer session was group-oriented and aimed at students rather than patients. In general computer teaching might be best used to complement rather than replace conventional teaching. IS - 0308-0110 IL - 0308-0110 DI - 1210 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial ID - 12028390 [pubmed] ID - 1210 [pii] PP - ppublish LG - English DP - 2002 May DC - 20020524 EZ - 2002/05/25 10:00 DA - 2002/06/22 10:01 DT - 2002/05/25 10:00 YR - 2002 ED - 20020621 RD - 20041117 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=12028390 <602. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11996260 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bucerius J AU - Metz S AU - Walther T AU - Falk V AU - Doll N AU - Noack F AU - Holzhey D AU - Diegeler A AU - Mohr FW FA - Bucerius, Jan FA - Metz, Sebastian FA - Walther, Thomas FA - Falk, Volkmar FA - Doll, Nicolas FA - Noack, Frank FA - Holzhey, David FA - Diegeler, Anno FA - Mohr, Friedrich W IN - Bucerius, Jan. Department of Cardiac Surgery, Heartcenter, University of Leipzig, Germany. bucerj@medizin.uni-leipzig.de TI - Endoscopic internal thoracic artery dissection leads to significant reduction of pain after minimally invasive direct coronary artery bypass graft surgery. SO - Annals of Thoracic Surgery. 73(4):1180-4, 2002 Apr AS - Ann Thorac Surg. 73(4):1180-4, 2002 Apr NJ - The Annals of thoracic surgery PI - Journal available in: Print PI - Citation processed from: Print JC - 683, 15030100r IO - Ann. Thorac. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - Netherlands MH - Aged MH - *Endoscopy MH - Female MH - Humans MH - Internal Mammary-Coronary Artery Anastomosis/mt [Methods] MH - *Internal Mammary-Coronary Artery Anastomosis MH - Male MH - *Mammary Arteries/su [Surgery] MH - Middle Aged MH - Minimally Invasive Surgical Procedures MH - Pain Measurement MH - Pain, Postoperative/dt [Drug Therapy] MH - *Pain, Postoperative MH - Robotics AB - BACKGROUND: The aim of this study was to evaluate postoperative pain levels after endoscopic versus conventional internal thoracic artery (ITA) dissection for minimally invasive direct coronary artery bypass graft surgery (MIDCABG) surgery. Results were compared with pain levels associated with conventional cardiac bypass operations through a median sternotomy. AB - METHODS: Of 190 patients included in this prospective study, 24 patients had endoscopic ITA takedown (MIDCABG-endo) using the da Vinci telemanipulator followed by a manual coronary anastomosis through a left minithoracotomy. A conventional MIDCABG operation (MIDCABG-conv) was performed in 73 patients with ITA preparation under direct vision. Postoperative pain levels after conventional CABG through a median sternotomy (CABG-conv, n = 93) served as controls. A standarized questionnaire including visual analog scale (VAS) was used for prospective pain assessment from POD 1 to 7. AB - RESULTS: Pain levels (VAS) declined in all groups from POD 1 to 7. Overall pain levels were significantly lower in the MIDCABG-endo group as compared with MIDCABG-conv and CABG-conv groups, respectively (p < 0.001, general linear model). There was no significant difference between the MIDCABG-conv and CABG-conv (p = not significant, general linear model) groups. Furthermore, patients after MIDCABG-endo required fewer nonsteroidal anti-inflammatory drugs and opioid medications, postoperatively. AB - CONCLUSIONS: An endoscopic ITA takedown in MIDCABG surgery leads to significantly reduced postoperative pain levels possibly because of less rib retraction. IS - 0003-4975 IL - 0003-4975 DI - S0003-4975(02)03385-4 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial ID - 11996260 [pubmed] ID - S0003-4975(02)03385-4 [pii] PP - ppublish LG - English DP - 2002 Apr DC - 20020508 EZ - 2002/05/09 10:00 DA - 2002/05/22 10:01 DT - 2002/05/09 10:00 YR - 2002 ED - 20020521 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11996260 <603. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11884798 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Eppley BL AU - Kilgo M AU - Coleman JJ 3rd FA - Eppley, Barry L FA - Kilgo, Matthew FA - Coleman, John J 3rd IN - Eppley, Barry L. Division of Plastic Surgery, Indiana University School of Medicine, 702 Barnhill Drive, #3540, Indianapolis, IN 46202, USA. beppley@iupui.edu TI - Cranial reconstruction with computer-generated hard-tissue replacement patient-matched implants: indications, surgical technique, and long-term follow-up. CM - Comment in: Arch Facial Plast Surg. 2003 Nov-Dec;5(6):533-4; PMID: 14623695 SO - Plastic & Reconstructive Surgery. 109(3):864-71, 2002 Mar AS - Plast Reconstr Surg. 109(3):864-71, 2002 Mar NJ - Plastic and reconstructive surgery PI - Journal available in: Print PI - Citation processed from: Print JC - 1306050, p9s IO - Plast. Reconstr. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adolescent MH - Adult MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Reconstructive Surgical Procedures/mt [Methods] MH - *Skull/su [Surgery] MH - Skull/tr [Transplantation] MH - *Surgery, Computer-Assisted MH - Time Factors AB - The aim of this clinical study was to evaluate the effectiveness and safety of using computer-generated alloplastic (hard-tissue replacement) implants for the reconstruction of large defects of the upper craniofacial region. Fourteen patients who had large (> 150 cm2) preexisting defects of the cranium or cranio-orbital region underwent surgical reconstruction. Preoperatively, a three-dimensional computed tomographic scan was obtained from which an anatomic model was fabricated. The defect in the model was then used to create an alloplastic (hard tissue-replacement polymer) implant for reconstruction and surgical placement. At the time of surgery, the implant was secured into position with either metal or resorbable fixation. In cases where the frontal sinus was in proximity to the implant, the frontal sinus was either cranialized and covered with a pericranial flap or obliterated with hydroxyapatite cement. In cases that had been previously irradiated or infected, wide bony debridement and coverage with a vascularized muscle was initially performed, followed by implant reconstruction 6 months later. All implants fit easily into the bone defects, and only four (29 percent) required some minor adjustments to complete the fit. All patients healed uneventfully. With a minimum of 1 year follow-up (average, 3 years) in all cases, excellent contours have been maintained and all patients have remained infection-free. In large cranial defects, custom implants fabricated from porous, hydrophilic hard-tissue replacement polymer provide an exacting anatomic fit and a solid stable reconstruction. This method of reconstruction in these defects is rapid and exact, and significantly reduces operative time. Critical attention must be paid, however, to management of the frontal sinus and preexisting bone infection and the quality of the overlying soft-tissue cover. IS - 0032-1052 IL - 0032-1052 PT - Clinical Trial PT - Journal Article ID - 11884798 [pubmed] PP - ppublish LG - English DP - 2002 Mar DC - 20020308 EZ - 2002/03/09 10:00 DA - 2002/05/23 10:01 DT - 2002/03/09 10:00 YR - 2002 ED - 20020517 RD - 20150624 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11884798 <604. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11758061 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Damiano RJ Jr AU - Ducko CT AU - Stephenson ER Jr AU - Lawton JS AU - Kuenzler RO AU - Chambers CE FA - Damiano, R J Jr FA - Ducko, C T FA - Stephenson, E R Jr FA - Lawton, J S FA - Kuenzler, R O FA - Chambers, C E IN - Damiano, R J Jr. Section of Cardiothoracic and Vascular Surgery, The Milton S. Hershey Medical Center, Penn State University, Hershey 17033, USA. rdamiano@psghs.edu TI - Robotically assisted coronary artery bypass grafting: a prospective single center clinical trial. SO - Journal of Cardiac Surgery. 15(4):256-65, 2000 Jul-Aug AS - J Card Surg. 15(4):256-65, 2000 Jul-Aug NJ - Journal of cardiac surgery PI - Journal available in: Print PI - Citation processed from: Print JC - ben, 8908809 IO - J Card Surg SB - Index Medicus CP - United States MH - Coronary Artery Bypass/is [Instrumentation] MH - *Coronary Artery Bypass/mt [Methods] MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Microsurgery/is [Instrumentation] MH - Middle Aged MH - Operating Rooms MH - Pilot Projects MH - Prospective Studies MH - *Robotics MH - Surgical Equipment MH - Time Factors MH - Vascular Patency AB - AIM: This prospective study was performed as a Phase 1 Food and Drug Administration clinical trial to assess the safety and feasibility of robotically assisted coronary artery bypass grafting (CABG). AB - METHODS: Eighteen patients undergoing elective CABG were enrolled in this study. Full sternotomy was performed in 17 of 18 patients, while cardiopulmonary bypass and cardioplegic arrest was used in all cases. Robotically assisted CABG of the left internal thoracic artery (LITA) to the left anterior descending artery (LAD) was performed through three ports using a robotically assisted microsurgical system. Conventional techniques were used to perform all other grafts. Blood flow in the LITA graft was measured in the operating room, and when necessary, angiography was performed. Six weeks after the operation, all patients underwent selective coronary angiography of the LITA graft. AB - RESULTS: Robotically assisted coronary artery anastomoses were successfully completed in all patients. Blood flow through the LITA graft was adequate in 16 of 18 patients (89%). The two inadequate grafts were revised successfully by hand. Six weeks after the operation, angiography demonstrated a graft patency of 100% (13 of 13). Mean follow-up has been over 190 days. All patients remain New York Heart Association Angina Class I. AB - CONCLUSION: Robotic assistance represents an enabling technology that may allow the surgeon to perform endoscopic coronary artery anastomoses. Further clinical trials are needed to explore the clinical potential and value of robotically assisted CABG. IS - 0886-0440 IL - 0886-0440 PT - Clinical Trial PT - Clinical Trial, Phase I PT - Journal Article ID - 11758061 [pubmed] PP - ppublish LG - English DP - 2000 Jul-Aug DC - 20011206 EZ - 2002/01/05 10:00 DA - 2002/02/23 10:01 DT - 2002/01/05 10:00 YR - 2000 ED - 20020222 RD - 20041117 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11758061 <605. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11780705 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Oenema A AU - Brug J AU - Lechner L FA - Oenema, A FA - Brug, J FA - Lechner, L IN - Oenema, A. Department of Health Education and Promotion, Maastricht University, The Netherlands. TI - Web-based tailored nutrition education: results of a randomized controlled trial. SO - Health Education Research. 16(6):647-60, 2001 Dec AS - Health Educ Res. 16(6):647-60, 2001 Dec NJ - Health education research PI - Journal available in: Print PI - Citation processed from: Print JC - bqp, 8608459 IO - Health Educ Res SB - Health Technology Assessment Journals CP - England MH - Adult MH - Awareness MH - Computer Literacy MH - *Computer-Assisted Instruction/is [Instrumentation] MH - *Computer-Assisted Instruction/mt [Methods] MH - Dietary Fats MH - Education, Distance MH - Feeding Behavior/px [Psychology] MH - Female MH - Fruit MH - Health Behavior MH - *Health Education/mt [Methods] MH - Humans MH - *Internet MH - Male MH - Middle Aged MH - Motivation MH - Netherlands MH - *Nutritional Sciences/ed [Education] MH - User-Computer Interface MH - Vegetables AB - There is ample evidence that printed, computer-tailored nutrition education is a more effective tool for motivating people to change to healthier diets than general nutrition education. New technology is now providing more advanced ways of delivering tailored messages, e.g. via the World Wide Web (WWW). Before disseminating a tailored intervention via the web, it is important to investigate the potential of web-based tailored nutrition education. The present study investigated the immediate impact of web-based computer-tailored nutrition education on personal awareness and intentions related to intake of fat, fruit and vegetables. A randomized controlled trial, with a pre-test-post-test control group design was conducted. Significant differences in awareness and intention to change were found between the intervention and control group at post-test. The tailored intervention was appreciated better, was rated as more personally relevant, and had more subjective impact on opinion and intentions to change than the general nutrition information. Computer literacy had no effect on these ratings. The results indicate that interactive, web-based computer-tailored nutrition education can lead to changes in determinants of behavior. Future research should be aimed at longer-term (behavioral) effects and the practicability of distributing tailored interventions via the WWW. RN - 0 (Dietary Fats) IS - 0268-1153 IL - 0268-1153 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 11780705 [pubmed] PP - ppublish LG - English DP - 2001 Dec DC - 20020108 EZ - 2002/01/10 10:00 DA - 2002/02/20 10:01 DT - 2002/01/10 10:00 YR - 2001 ED - 20020219 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11780705 <606. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11605107 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Vara-Thorbeck C AU - Munoz VF AU - Toscano R AU - Gomez J AU - Fernandez J AU - Felices M AU - Garcia-Cerezo A FA - Vara-Thorbeck, C FA - Munoz, V F FA - Toscano, R FA - Gomez, J FA - Fernandez, J FA - Felices, M FA - Garcia-Cerezo, A IN - Vara-Thorbeck, C. Catedra de Cirugia General, Facultad de Medicina, Universidad de Malaga, Colonia Sta, Ines, S/N, Spain. TI - A new robotic endoscope manipulator. A preliminary trial to evaluate the performance of a voice-operated industrial robot and a human assistant in several simulated and real endoscopic operations. SO - Surgical Endoscopy. 15(9):924-7, 2001 Sep AS - Surg Endosc. 15(9):924-7, 2001 Sep NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Animals MH - *Endoscopy/mt [Methods] MH - Equipment Design/mt [Methods] MH - Humans MH - Models, Animal MH - *Robotics/is [Instrumentation] MH - Robotics/mt [Methods] MH - Stomach/su [Surgery] MH - Suture Techniques MH - Swine MH - User-Computer Interface MH - Video-Assisted Surgery/is [Instrumentation] MH - Video-Assisted Surgery/mt [Methods] MH - Voice AB - We report our learning experience in simulated and real surgical tasks with a new voice-controlled robotic endoscope manipulator: an industrial robot with the tool-holder arm modified to support the optic and camera. The manipulator control-card programs have been rewritten to meet the needs of endoscopic surgeons. For this preliminary work, systems engineers with an additional monitor monitored, recorded, and compared the percentage effectiveness and precision of the responses of the robotic and human assistant to successive oral commands during the several different experimental surgical tasks. Simultaneously, to help develop this voice-commanded system for future, more precise robotic manipulation of surgical instruments, they measured the cartesian and spherical coordinates of successive positions of the optic. In unexpectedly difficult experimental conditions, the tireless robot proved more precise and effective than the demonstrably fatigable human: the steadier screen images of the robotic manipulations helped the surgeon tie knots in 7-0 sutures. ES - 1432-2218 IL - 0930-2794 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial ID - 11605107 [pubmed] PP - ppublish PH - 1999/07/09 [received] PH - 2001/01/02 [accepted] LG - English EP - 20010619 DP - 2001 Sep DC - 20011017 EZ - 2001/10/18 10:00 DA - 2002/02/08 10:01 DT - 2001/10/18 10:00 YR - 2001 ED - 20020207 RD - 20041117 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11605107 <607. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11605106 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Cadiere GB AU - Himpens J AU - Vertruyen M AU - Bruyns J AU - Germay O AU - Leman G AU - Izizaw R FA - Cadiere, G B FA - Himpens, J FA - Vertruyen, M FA - Bruyns, J FA - Germay, O FA - Leman, G FA - Izizaw, R IN - Cadiere, G B. Gastro Intestinal Surgery Department, CHU Saint-Pierre, 322, Rue Haute 1000, Brussels, Belgium. coelio@resulb.ulb.ac.be TI - Evaluation of telesurgical (robotic) NISSEN fundoplication. SO - Surgical Endoscopy. 15(9):918-23, 2001 Sep AS - Surg Endosc. 15(9):918-23, 2001 Sep NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adolescent MH - Adult MH - Feasibility Studies MH - Female MH - Fundoplication/is [Instrumentation] MH - *Fundoplication/mt [Methods] MH - Fundoplication/st [Standards] MH - *Gastroesophageal Reflux/su [Surgery] MH - Humans MH - *Laparoscopy/mt [Methods] MH - Laparoscopy/st [Standards] MH - Male MH - Middle Aged MH - Remote Consultation/mt [Methods] MH - Remote Consultation/st [Standards] MH - *Robotics/mt [Methods] MH - Robotics/st [Standards] MH - Telemedicine/is [Instrumentation] MH - *Telemedicine/mt [Methods] MH - Telemedicine/st [Standards] MH - Time Factors MH - Treatment Outcome AB - BACKGROUND: The laparoscopic surgical approach has proven its benefit for the patient. There are however several shortcomings, which have triggered considerable research for improvement. One improvement may be the introduction of telesurgery by the interposition of a computer interface between surgeon and patient. AB - MATERIAL AND METHODS: A prospective randomized study was conducted in an advanced laparoscopic procedure, Nissen fundoplication. The control group underwent the conventional laparoscopic approach, while the investigational group underwent the telesurgical approach. AB - RESULTS: Feasibility was 100%. The procedure was more time consuming in the Telesurgical group, at all stages of the operation. Mortality was nil and morbidity was comparable in both groups. AB - CONCLUSION: The telesurgical approach is feasible in advanced laparoscopic procedures like Nissen fundoplication. At the present time there is however no obvious added benefit from this new technique. ES - 1432-2218 IL - 0930-2794 DO - https://dx.doi.org/10.1007/s004640000217 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 11605106 [pubmed] ID - 10.1007/s004640000217 [doi] PP - ppublish LG - English EP - 20010705 DP - 2001 Sep DC - 20011017 EZ - 2001/10/18 10:00 DA - 2002/02/08 10:01 DT - 2001/10/18 10:00 YR - 2001 ED - 20020207 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11605106 <608. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11605613 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Damiano RJ Jr AU - Tabaie HA AU - Mack MJ AU - Edgerton JR AU - Mullangi C AU - Graper WP AU - Prasad SM FA - Damiano, R J Jr FA - Tabaie, H A FA - Mack, M J FA - Edgerton, J R FA - Mullangi, C FA - Graper, W P FA - Prasad, S M IN - Damiano, R J Jr. Division of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, Missouri 63110, USA. damianor@msnotes.wustl.edu TI - Initial prospective multicenter clinical trial of robotically-assisted coronary artery bypass grafting. SO - Annals of Thoracic Surgery. 72(4):1263-8; discussion 1268-9, 2001 Oct AS - Ann Thorac Surg. 72(4):1263-8; discussion 1268-9, 2001 Oct NJ - The Annals of thoracic surgery PI - Journal available in: Print PI - Citation processed from: Print JC - 683, 15030100r IO - Ann. Thorac. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - Netherlands MH - Aged MH - Anastomosis, Surgical/is [Instrumentation] MH - *Coronary Artery Bypass/is [Instrumentation] MH - *Coronary Disease/su [Surgery] MH - Female MH - Humans MH - Male MH - Microsurgery/is [Instrumentation] MH - Middle Aged MH - Prospective Studies MH - Reoperation MH - *Robotics/is [Instrumentation] MH - Surgical Equipment MH - Thoracic Arteries/su [Surgery] AB - BACKGROUND: This multicenter prospective trial was designed to assess the safety and efficacy of using a robotically-assisted microsurgical system to create endoscopic coronary anastomoses. AB - METHODS: . Thirty-two patients scheduled for elective primary coronary surgery underwent endoscopic anastomosis of the left internal thoracic artery (LITA) to the left anterior descending (LAD) artery. Three thoracic ports (two for instruments and one for a camera) were placed, and a robotic system was used to perform the LITA-LAD graft. Conventional techniques were used to perform the other grafts. Thirty-one patients underwent median sternotomy and 1 patient underwent a limited anterior thoracotomy. AB - RESULTS: . Graft flow was measured in the operating room and averaged 37 +/- 19 mL/min. Mean anastomosis time was 24 +/- 9 minutes. There were three intraoperative revisions (9%). Two were for inadequate flow and one for an inadvertent injury. Each of these grafts was successfully revised by hand. There were no technical failures of the robotic system. Average postoperative length of stay was 5.5 +/- 2.7 days. There were three reoperations for bleeding, but none of these were related to the LAD anastomosis. Two months following the operation, selective angiography revealed a graft patency of 93%. The patients have been followed for 16 +/- 4 months. AB - CONCLUSIONS: This initial prospective multicenter trial documents the feasibility of robotically-assisted coronary bypass grafting. Further trials are warranted to establish the safety and efficacy of this new technology. IS - 0003-4975 IL - 0003-4975 DI - S0003-4975(01)02980-0 PT - Clinical Trial PT - Journal Article PT - Multicenter Study ID - 11605613 [pubmed] ID - S0003-4975(01)02980-0 [pii] PP - ppublish LG - English DP - 2001 Oct DC - 20011017 EZ - 2001/10/19 10:00 DA - 2002/01/05 10:01 DT - 2001/10/19 10:00 YR - 2001 ED - 20011204 RD - 20041117 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11605613 <609. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11568039 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kappert U AU - Schneider J AU - Cichon R AU - Gulielmos V AU - Tugtekin SM AU - Nicolai J AU - Matschke K AU - Schueler S FA - Kappert, U FA - Schneider, J FA - Cichon, R FA - Gulielmos, V FA - Tugtekin, S M FA - Nicolai, J FA - Matschke, K FA - Schueler, S IN - Kappert, U. Department of Cardiovascular Surgery, Cardiovascular Institute, University of Dresden, Germany. Monika.Weber.hkz_dd@t-online.de TI - Development of robotic enhanced endoscopic surgery for the treatment of coronary artery disease. SO - Circulation. 104(12 Suppl 1):I102-7, 2001 Sep 18 AS - Circulation. 104(12 Suppl 1):I102-7, 2001 Sep 18 NJ - Circulation PI - Journal available in: Print PI - Citation processed from: Internet JC - daw, 0147763 IO - Circulation SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Anesthesia/mt [Methods] MH - Coronary Artery Bypass/ae [Adverse Effects] MH - *Coronary Artery Bypass/is [Instrumentation] MH - *Coronary Disease/su [Surgery] MH - Electrocardiography MH - Endoscopy/ae [Adverse Effects] MH - *Endoscopy/mt [Methods] MH - Endoscopy/sn [Statistics & Numerical Data] MH - Exercise Test MH - Feasibility Studies MH - Female MH - Follow-Up Studies MH - Hemorrhage/et [Etiology] MH - Humans MH - Male MH - Mammary Arteries/tr [Transplantation] MH - Middle Aged MH - Minimally Invasive Surgical Procedures/ae [Adverse Effects] MH - *Minimally Invasive Surgical Procedures/is [Instrumentation] MH - Minimally Invasive Surgical Procedures/sn [Statistics & Numerical Data] MH - Postoperative Period MH - Robotics/is [Instrumentation] MH - *Robotics MH - Survival Rate MH - Time Factors MH - Treatment Outcome AB - BACKGROUND: The introduction of robotic enhanced surgery demanded stepwise development of performed procedures on the basis of growing experience of the operating team. AB - METHODS AND RESULTS: Between May 1999 and January 2001, this new wrist-enhanced instrumentation was used in 201 patients (156 men and 45 women, median age 64+/-10.5 years, left ventricular ejection fraction 68+/-12.4%). During the development of robotic enhanced CABG, the patients were divided into 3 groups. Group A (n=156) consisted of patients in whom the robotic system was used to harvesting the left or right internal mammary artery, or both, whereas the anastomoses were performed directly through a small chest incision. In group B (n=37), the harvest of the internal mammary arteries and the coronary anastomoses were performed totally endoscopically. In a third early group C, patient (n=8) were treated with robotic enhanced CABG via a median sternotomy already preoperatively planned, whereas gradual step-by-step application of robotic instrumentation and its feasibility were assessed. The survival rate was 99.4%. One patient (0.6%) died due to pneumonia on postoperative day 16. Conversion rate to median sternotomy was 5%. The left and right internal mammary artery conduits could be successfully harvested in 98% and 100%, respectively. The time of dissection of the left internal mammary artery could be significantly reduced alone by increasing experience. All patients were discharged from the hospital after a mean of 7 days. In 9 patients (4.5%), bleeding required reexploration. AB - CONCLUSIONS: The introduction of this new surgical tool enables the development of new endoscopic procedures. Our results gained during the development of robotic enhanced CABG motivate us to establish a set standard for the totally endoscopic treatment of patients with 1-vessel coronary artery disease. ES - 1524-4539 IL - 0009-7322 PT - Clinical Trial PT - Journal Article ID - 11568039 [pubmed] PP - ppublish LG - English DP - 2001 Sep 18 DC - 20010924 EZ - 2001/09/25 10:00 DA - 2001/10/05 10:01 DT - 2001/09/25 10:00 YR - 2001 ED - 20011004 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11568039 <610. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11421824 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Nilsson LB AU - Eldrup N AU - Berthelsen PG FA - Nilsson, L B FA - Eldrup, N FA - Berthelsen, P G IN - Nilsson, L B. Department of Anaesthesiology, Gentofte Hospital, University of Copenhagen, Denmark. TI - Lack of agreement between thermodilution and carbon dioxide-rebreathing cardiac output. SO - Acta Anaesthesiologica Scandinavica. 45(6):680-5, 2001 Jul AS - Acta Anaesthesiol Scand. 45(6):680-5, 2001 Jul NJ - Acta anaesthesiologica Scandinavica PI - Journal available in: Print PI - Citation processed from: Print JC - 0370270 IO - Acta Anaesthesiol Scand SB - Index Medicus CP - England MH - Adult MH - Blood Gas Analysis MH - *Carbon Dioxide/an [Analysis] MH - *Cardiac Output/ph [Physiology] MH - Female MH - Humans MH - Male MH - Middle Aged MH - Oximetry MH - Reproducibility of Results MH - Thermodilution AB - BACKGROUND: A continuous, accurate, non-invasive monitor of cardiac output would represent a major step forward in patient management. A cardiac output computer, NICO2, based on the Fick principle and an automatic partial carbon dioxide (CO2)-rebreathing technique has just become available. We compared the performance of this monitor with the standard thermodilution method. AB - METHODS: Thirty patients were investigated after cardiac surgery. Replicate measurements were performed simultaneously with the thermodilution and NICO2 techniques. An Altman-Bland analysis was used to assess repeatability of each of the two methods and to determine the agreement between the two techniques. AB - RESULTS: The repeatabilities of thermodilution and CO2-rebreathing cardiac output were excellent, with coefficients of repeatability of 0.35 l/min and 0.60 l/min. Mean thermodilution and NICO2 cardiac output were 4.4 l/min (SD 0.9, range 2.7-6.1) and 4.6 l/min (SD 1.3, range 1.6-6.9). A comparison of the methods, however, revealed excessive limits of agreement (+/-1.80 l/min). AB - CONCLUSION: The agreement between the NICO2 derived cardiac output and the de facto standard - thermodilution cardiac output - is poor. The methods are not interchangeable with the present version of the NICO2. The repeatability of the partial CO2-rebreathing technique holds promise that a sufficient accuracy may be obtained by suitable modifications of the monitor's algorithms. RN - 142M471B3J (Carbon Dioxide) IS - 0001-5172 IL - 0001-5172 DI - aas450604 PT - Clinical Trial PT - Journal Article ID - 11421824 [pubmed] ID - aas450604 [pii] PP - ppublish LG - English DP - 2001 Jul DC - 20010625 EZ - 2001/06/26 10:00 DA - 2001/09/21 10:01 DT - 2001/06/26 10:00 YR - 2001 ED - 20010920 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11421824 <611. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11435056 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Mathew JP AU - Weatherwax KJ AU - East CJ AU - White WD AU - Reves JG FA - Mathew, J P FA - Weatherwax, K J FA - East, C J FA - White, W D FA - Reves, J G IN - Mathew, J P. Division of Cardiothoracic Anesthesiology and Critical Care, Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA. mathe014@mc.duke.edu TI - Bispectral analysis during cardiopulmonary bypass: the effect of hypothermia on the hypnotic state. SO - Journal of Clinical Anesthesia. 13(4):301-5, 2001 Jun AS - J Clin Anesth. 13(4):301-5, 2001 Jun NJ - Journal of clinical anesthesia PI - Journal available in: Print PI - Citation processed from: Print JC - an9, 8812166 IO - J Clin Anesth SB - Index Medicus CP - United States MH - Adjuvants, Anesthesia/pk [Pharmacokinetics] MH - Aged MH - Aging MH - Analgesics, Opioid/pk [Pharmacokinetics] MH - *Anesthesia, General MH - Anesthetics, Inhalation/pk [Pharmacokinetics] MH - Brain/me [Metabolism] MH - *Cardiopulmonary Bypass MH - *Electroencephalography/de [Drug Effects] MH - Female MH - Fentanyl/pk [Pharmacokinetics] MH - Humans MH - *Hypothermia, Induced MH - Isoflurane/pk [Pharmacokinetics] MH - Male MH - Midazolam/pk [Pharmacokinetics] MH - Middle Aged MH - Monitoring, Intraoperative MH - Prospective Studies AB - STUDY OBJECTIVE: To evaluate the hypothesis that the bispectral index (BIS) is not affected by the hypothermia that is associated with cardiopulmonary bypass (CPB). AB - DESIGN: Prospective, observational study. AB - SETTING: Cardiac surgical operating suite of a university medical center. AB - PATIENTS: 100 patients undergoing cardiac surgery requiring CPB. AB - INTERVENTIONS: A constant effect site concentration of 2.2 ng/mL for fentanyl and 60 ng/mL for midazolam was maintained throughout surgery using a computer-assisted continuous infusion technique. AB - MEASUREMENTS: The BIS value, percent isoflurane administered, predicted brain concentrations of midazolam and fentanyl, and nasopharyngeal temperature were recorded before CPB, at 15 minutes after the onset of CPB, at placement of the aortic cross-clamp, at start of rewarming, on separation from CPB, and 15 minutes after the end of CPB. Data were analyzed using a repeated-measures mixed-effects method, taking into account temperature, age, and predicted level of each anesthetic. AB - MAIN RESULTS: A significant overall association between temperature and BIS was observed independent of patient age, predicted brain midazolam or fentanyl concentration, percent isoflurane administered, and surgical time point (p < 0.001). The BIS is estimated to decrease by 1.12 units for each degree Celsius decrease in body temperature. AB - CONCLUSIONS: Hypothermia decreases the BIS by 1.12 units per degree Celsius decline in temperature. RN - 0 (Adjuvants, Anesthesia) RN - 0 (Analgesics, Opioid) RN - 0 (Anesthetics, Inhalation) RN - CYS9AKD70P (Isoflurane) RN - R60L0SM5BC (Midazolam) RN - UF599785JZ (Fentanyl) IS - 0952-8180 IL - 0952-8180 DI - S0952-8180(01)00275-6 PT - Clinical Trial PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. ID - 11435056 [pubmed] ID - S0952-8180(01)00275-6 [pii] PP - ppublish GI - No: M01 RR-30 Organization: (RR) *NCRR NIH HHS* Country: United States LG - English DP - 2001 Jun DC - 20010703 EZ - 2001/07/04 10:00 DA - 2001/09/14 10:01 DT - 2001/07/04 10:00 YR - 2001 ED - 20010913 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11435056 <612. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11397745 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lennox AS AU - Osman LM AU - Reiter E AU - Robertson R AU - Friend J AU - McCann I AU - Skatun D AU - Donnan PT FA - Lennox, A S FA - Osman, L M FA - Reiter, E FA - Robertson, R FA - Friend, J FA - McCann, I FA - Skatun, D FA - Donnan, P T IN - Lennox, A S. Department of General Practice and Primary Care, University of Aberdeen, Aberdeen AB25 2AY. TI - Cost effectiveness of computer tailored and non-tailored smoking cessation letters in general practice: randomised controlled trial. SO - BMJ. 322(7299):1396, 2001 Jun 09 AS - BMJ. 322(7299):1396, 2001 Jun 09 NJ - BMJ (Clinical research ed.) PI - Journal available in: Print PI - Citation processed from: Print JC - 8900488, bmj, 101090866 IO - BMJ PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC32255 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - Adolescent MH - Adult MH - Aged MH - *Automatic Data Processing MH - *Correspondence as Topic MH - Cost-Benefit Analysis MH - Cotinine/an [Analysis] MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - *Patient Education as Topic/mt [Methods] MH - Saliva/ch [Chemistry] MH - Smoking Cessation/ec [Economics] MH - *Smoking Cessation/mt [Methods] MH - Surveys and Questionnaires AB - OBJECTIVES: To develop and evaluate, in a primary care setting, a computerised system for generating tailored letters about smoking cessation. AB - DESIGN: Randomised controlled trial. AB - SETTING: Six general practices in Aberdeen, Scotland. AB - PARTICIPANTS: 2553 smokers aged 17 to 65. AB - INTERVENTIONS: All participants received a questionnaire asking about their smoking. Participants subsequently received either a computer tailored or a non-tailored, standard letter on smoking cessation, or no letter. AB - MAIN OUTCOME MEASURES: Prevalence of validated abstinence at six months; change in intention to stop smoking in the next six months. AB - RESULTS: The validated cessation rate at six months was 3.5% (30/857) (95% confidence interval 2.3% to 4.7%) for the tailored letter group, 4.4% (37/846) (3.0% to 5.8%) for the non-tailored letter group, and 2.6% (22/850) (1.5% to 3.7%) for the control (no letter) group. After adjustment for significant covariates, the cessation rate was 66% greater (-4% to 186%; P=0.07) in the non-tailored letter group than that in the no letter group. Among participants who smoked <20 cigarettes per day, the cessation rate in the non-tailored letter group was 87% greater (0% to 246%; P=0.05) than that in the no letter group. Among heavy smokers who did not quit, a 76% higher rate of positive shift in "stage of change" (intention to quit within a particular period of time) was seen compared with those who received no letter (11% to 180%; P=0.02). The increase in cost for each additional quitter in the non-tailored letter group compared with the no letter group was pound 89. AB - CONCLUSIONS: In a large general practice, a brief non-tailored letter effectively increased cessation rates among smokers. A tailored letter was not effective in increasing cessation rates but promoted shift in movement towards cessation ("stage of change") in heavy smokers. As a pragmatic tool to encourage cessation of smoking, a mass mailing of non-tailored letters from general practices is more cost effective than computer tailored letters or no letters. RN - K5161X06LL (Cotinine) IS - 0959-8138 IL - 0959-535X PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 11397745 [pubmed] ID - PMC32255 [pmc] PP - ppublish LG - English DP - 2001 Jun 09 DC - 20010608 EZ - 2001/06/09 10:00 DA - 2001/07/06 10:01 DT - 2001/06/09 10:00 YR - 2001 ED - 20010705 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11397745 <613. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11309003 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hoeksel SA AU - Blom JA AU - Jansen JR AU - Maessen JG AU - Schreuder JJ FA - Hoeksel, S A FA - Blom, J A FA - Jansen, J R FA - Maessen, J G FA - Schreuder, J J IN - Hoeksel, S A. Department of Anesthesiology, Cardiovascular Research Institute, Maastricht University, Maastricht, The Netherlands. TI - Computer control versus manual control of systemic hypertension during cardiac surgery. SO - Acta Anaesthesiologica Scandinavica. 45(5):553-7, 2001 May AS - Acta Anaesthesiol Scand. 45(5):553-7, 2001 May NJ - Acta anaesthesiologica Scandinavica PI - Journal available in: Print PI - Citation processed from: Print JC - 0370270 IO - Acta Anaesthesiol Scand SB - Index Medicus CP - England MH - Adult MH - Cardiac Output/de [Drug Effects] MH - *Cardiac Surgical Procedures MH - Cardiopulmonary Bypass MH - Computers MH - Hemodynamics/de [Drug Effects] MH - Hemodynamics/ph [Physiology] MH - Humans MH - *Hypertension/dt [Drug Therapy] MH - Infusions, Intravenous MH - Male MH - Monitoring, Intraoperative MH - Nitroglycerin/ad [Administration & Dosage] MH - Nitroglycerin/tu [Therapeutic Use] MH - Nitroprusside/ad [Administration & Dosage] MH - Nitroprusside/tu [Therapeutic Use] MH - *Vasodilator Agents/ad [Administration & Dosage] MH - *Vasodilator Agents/tu [Therapeutic Use] AB - BACKGROUND: We recently demonstrated the feasibility of computer controlled infusion of vasoactive drugs for the control of systemic hypertension during cardiac surgery. The objective of the current study was to investigate the effects of computer controlled blood pressures on hemodynamic stability when compared to conventional manual control. AB - METHOD: Systemic artery blood pressures were managed either by computer (80 patients) or by a well-trained anesthesiologist (80 patients). The vasodilator drugs sodium nitroprusside and nitroglycerin were used. Hemodynamic stability was determined from the standard deviation of the mean arterial pressure samples and from the percentages of time that arterial pressure was hypertensive or hypotensive. AB - RESULTS: The average standard deviation of the mean arterial pressure samples was smaller for the computer controlled than for the manually controlled group: 7.5+/-2.2 (mean+/-SD) versus 8.9+/-2.3 mmHg (P<0.0001). The systemic artery pressure was less hypertensive and less hypotensive in the computer controlled than in the manually controlled group: 9.4+/-5.7 versus 13.1+/-6.0% (P<0.0001) and 8.0+/-5.9 versus 11.8+/-7.4% (P<0.0001), respectively. AB - CONCLUSION: We conclude that, compared with manual control, computer control of systemic hypertension significantly improved hemodynamic stability during cardiac surgery. RN - 0 (Vasodilator Agents) RN - 169D1260KM (Nitroprusside) RN - G59M7S0WS3 (Nitroglycerin) IS - 0001-5172 IL - 0001-5172 DI - aas450506 PT - Clinical Trial PT - Journal Article ID - 11309003 [pubmed] ID - aas450506 [pii] PP - ppublish LG - English DP - 2001 May DC - 20010419 EZ - 2001/04/20 10:00 DA - 2001/07/06 10:01 DT - 2001/04/20 10:00 YR - 2001 ED - 20010705 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11309003 <614. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11371730 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Prasad SM AU - Ducko CT AU - Stephenson ER AU - Chambers CE AU - Damiano RJ Jr FA - Prasad, S M FA - Ducko, C T FA - Stephenson, E R FA - Chambers, C E FA - Damiano , R J Jr IN - Prasad, S M. Division of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, Missouri, USA. TI - Prospective clinical trial of robotically assisted endoscopic coronary grafting with 1-year follow-up. SO - Annals of Surgery. 233(6):725-32, 2001 Jun AS - Ann Surg. 233(6):725-32, 2001 Jun NJ - Annals of surgery PI - Journal available in: Print PI - Citation processed from: Print JC - 67s, 0372354 IO - Ann. Surg. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1421314 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Aged, 80 and over MH - *Coronary Artery Bypass/mt [Methods] MH - *Endoscopy/mt [Methods] MH - Follow-Up Studies MH - Humans MH - Internal Mammary-Coronary Artery Anastomosis MH - Length of Stay MH - *Robotics/is [Instrumentation] MH - *Thoracic Surgery, Video-Assisted/is [Instrumentation] MH - Time Factors MH - Vascular Patency AB - OBJECTIVE: To follow up in prospective fashion patients with coronary artery anastomoses completed endoscopically with robotic assistance. The robotic system was evaluated for safety and its effectiveness in completing microsurgical coronary anastomoses. AB - SUMMARY BACKGROUND DATA: Recently there has been an interest in using robotics and computers to enhance the surgeon's ability to perform endoscopic cardiac surgery. This interest has stemmed from the rapid advancement of technology and the desire to make cardiac surgery less invasive. Using traditional endoscopic instruments, it has not been possible to perform coronary surgery. AB - METHODS: Nineteen patients underwent robotically assisted endoscopic coronary artery bypass grafting of the left internal thoracic artery (LITA) to the left anterior descending artery (LAD). Two robotic instruments and one endoscopic camera were placed through three 5-mm ports. A robotic system was used to construct the LITA-LAD anastomosis. All other required grafts were completed by conventional techniques. AB - RESULTS: Seventeen LITA-LAD grafts (89%) had adequate intraoperative flow. The mean LITA-LAD graft flow was 38.5 +/- 5 mL/min. At 8 weeks, LITA-LAD grafts were assessed by angiography and showed 100% patency with thrombolysis in myocardial infarction (TIMI) I flow. At a mean follow-up of 17 +/- 4.2 months, all patients were NYHA class I and there were no adverse cardiac events. AB - CONCLUSIONS: The results from the first prospective clinical trial of robotically assisted endoscopic coronary bypass surgery in the United States showed favorable short-term outcomes with no adverse events. Robotic assistance is an enabling technology allowing the performance of endoscopic coronary anastomoses. IS - 0003-4932 IL - 0003-4932 PT - Clinical Trial PT - Evaluation Studies PT - Journal Article ID - 11371730 [pubmed] ID - PMC1421314 [pmc] PP - ppublish LG - English DP - 2001 Jun DC - 20010523 EZ - 2001/05/24 10:00 DA - 2001/06/22 10:01 DT - 2001/05/24 10:00 YR - 2001 ED - 20010621 RD - 20140613 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11371730 <615. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11232858 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Sheu MT AU - Yeh GC AU - Ke WT AU - Ho HO FA - Sheu, M T FA - Yeh, G C FA - Ke, W T FA - Ho, H O IN - Sheu, M T. Graduate Institute of Pharmaceutical Sciences, Taipei Medical College, Taiwan, ROC. TI - Development of a high-performance liquid chromatographic method for bioequivalence study of flavoxate tablets. SO - Journal of Chromatography. B, Biomedical Sciences & Applications. 751(1):79-86, 2001 Feb 10 AS - J Chromatogr B Biomed Sci Appl. 751(1):79-86, 2001 Feb 10 NJ - Journal of chromatography. B, Biomedical sciences and applications PI - Journal available in: Print PI - Citation processed from: Print JC - cxn, 9714109 IO - J. Chromatogr. B Biomed. Sci. Appl. SB - Index Medicus CP - Netherlands MH - Adult MH - *Chromatography, High Pressure Liquid/mt [Methods] MH - *Flavoxate/aa [Analogs & Derivatives] MH - Flavoxate/bl [Blood] MH - *Flavoxate/pk [Pharmacokinetics] MH - Humans MH - Male MH - Parasympatholytics/pk [Pharmacokinetics] MH - Tablets MH - Therapeutic Equivalency AB - An improved HPLC method was developed for the concentration determination of the metabolite of flavoxate, 3-methyl-flavone-8-carboxylic acid (MFCA), in plasma in an attempt to compare two flavoxate tablet formulations. This HPLC method was validated by examining the precision and the accuracy for inter-day and intra-day runs in a linear concentration range of 0.1-24 microg/ml. The coefficients of variation (C.V.) of inter-day and intra-day assays were 0.24-7.18% and 0.06-5.70%, respectively. The standard errors of mean (S.E.M.) were -0.004-8.68% and -2.52-4.86% for inter-day and intra-day assays, respectively. Bioequivalence of the two formulations was determined on 12 normal healthy male volunteers in a single-dose, two-period, two-sequence, two-treatment crossover study. MFCA plasma concentrations were analyzed with this validated HPLC method. The normal pivotal parameters, AUC(0-last), AUC(0-inf) and Cmax, were calculated and compared using the SAS General Linear Model computer program. The two one-sided t distribution test was also performed, as well as the 90% confidence-interval method, for the mean difference of the three pivotal parameters. The results suggest that these two flavoxate tablet formulations are non-bioequivalent when orally administered in a 400-mg dose of two tablets. This result was consistent with the in vitro dissolution of these two formulations. RN - 0 (Parasympatholytics) RN - 0 (Tablets) RN - 3E74Y80MEY (Flavoxate) RN - O8RCM70C48 (3-methylflavone-8-carboxylic acid) IS - 1387-2273 IL - 1387-2273 PT - Clinical Trial PT - Evaluation Studies PT - Journal Article PT - Validation Studies ID - 11232858 [pubmed] PP - ppublish LG - English DP - 2001 Feb 10 DC - 20010305 EZ - 2001/03/10 10:00 DA - 2001/06/08 10:01 DT - 2001/03/10 10:00 YR - 2001 ED - 20010607 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11232858 <616. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11178294 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kappert U AU - Cichon R AU - Gulielmos V AU - Schneider J AU - Schramm I AU - Nicolai J AU - Tugtekin SM AU - Schueler S FA - Kappert, U FA - Cichon, R FA - Gulielmos, V FA - Schneider, J FA - Schramm, I FA - Nicolai, J FA - Tugtekin, S M FA - Schueler, S IN - Kappert, U. Department of Cardiac Surgery, Department of Anesthesiology; Cardiovascular Institute, University of Dresden, Germany. TI - Robotic-enhanced Dresden technique for minimally invasive bilateral internal mammary artery grafting. SO - Heart Surgery Forum. 3(4):319-21, 2000 AS - Heart Surg Forum. 3(4):319-21, 2000 NJ - The heart surgery forum PI - Journal available in: Print PI - Citation processed from: Print JC - duc, 100891112 IO - Heart Surg Forum SB - Index Medicus CP - United States MH - Aged MH - Coronary Disease/di [Diagnosis] MH - *Coronary Disease/su [Surgery] MH - Female MH - Follow-Up Studies MH - Graft Survival MH - Humans MH - Internal Mammary-Coronary Artery Anastomosis/is [Instrumentation] MH - *Internal Mammary-Coronary Artery Anastomosis/mt [Methods] MH - Male MH - Middle Aged MH - Minimally Invasive Surgical Procedures/is [Instrumentation] MH - Minimally Invasive Surgical Procedures/mt [Methods] MH - *Robotics MH - Sensitivity and Specificity MH - Severity of Illness Index MH - Tissue and Organ Harvesting/mt [Methods] MH - Treatment Outcome MH - Vascular Patency AB - BACKGROUND: The introduction of robotic-enhanced endoscopic instrumentation systems allows the surgeon to perform arterial revascularization for multivessel coronary artery disease without sternotomy. AB - METHODS: From April 1999, 27 patients (6 female, 21 male, median age 63 +/- 8.2 years) suffering from multivessel coronary artery disease were treated surgically using arterial revascularization by means of bilateral internal mammary artery (BIMA) grafting. Both arteries were harvested totally endoscopically using the da Vinci robotic surgical system (Intuitive Surgical, Mountain View, CA). These vessels were anastomosed using the "Dresden Technique" via a left minithoracotomy in the second intercostal space. AB - RESULTS: All patients survived the operation. The mean duration of surgery was 240 +/- 79.4 minutes. Bilateral internal mammary artery harvesting time was 88.5 +/- 15.9 minutes, and cross-clamp time was 38 +/- 10.9 minutes. An average of 2.07 anastomoses were performed per operation. Postoperatively, the patients remained in ICU for 20 +/- 2.4 hours. One patient needed reexploration due to bleeding. AB - CONCLUSIONS: Bilateral internal mammary artery harvesting can be achieved safely with the use of wrist-enhanced instrumentation. The robotic surgical system introduces into surgical practice a new type of treatment of coronary artery disease, helping to perform arterial revascularization with a distinctly reduced surgical trauma. IS - 1098-3511 IL - 1098-3511 PT - Clinical Trial PT - Journal Article ID - 11178294 [pubmed] PP - ppublish PH - 2000/06/08 [accepted] LG - English DP - 2000 DC - 20010222 EZ - 2001/02/15 11:00 DA - 2001/05/22 10:01 DT - 2001/02/15 11:00 YR - 2000 ED - 20010510 RD - 20141120 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11178294 <617. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11240262 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Damen EM AU - Brugmans MJ AU - van der Horst A AU - Bos L AU - Lebesque JV AU - Mijnheer BJ AU - McShan DL AU - Fraass BA AU - Kessler ML FA - Damen, E M FA - Brugmans, M J FA - van der Horst, A FA - Bos, L FA - Lebesque, J V FA - Mijnheer, B J FA - McShan, D L FA - Fraass, B A FA - Kessler, M L IN - Damen, E M. Radiotherapy Division, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Huis, Amsterdam, The Netherlands. damen@nki.nl TI - Planning, computer optimization, and dosimetric verification of a segmented irradiation technique for prostate cancer. SO - International Journal of Radiation Oncology, Biology, Physics. 49(4):1183-95, 2001 Mar 15 AS - Int J Radiat Oncol Biol Phys. 49(4):1183-95, 2001 Mar 15 NJ - International journal of radiation oncology, biology, physics PI - Journal available in: Print PI - Citation processed from: Print JC - g97, 7603616 IO - Int. J. Radiat. Oncol. Biol. Phys. SB - Index Medicus CP - United States MH - Algorithms MH - Humans MH - Male MH - Netherlands MH - *Phantoms, Imaging MH - *Prostatic Neoplasms/rt [Radiotherapy] MH - Radiation Protection/mt [Methods] MH - Radiometry MH - Radiotherapy Dosage MH - *Radiotherapy Planning, Computer-Assisted/mt [Methods] MH - *Radiotherapy, Conformal/mt [Methods] MH - *Rectum MH - Time Factors AB - PURPOSE: To develop and verify a multisegment technique for prostate irradiation that results in better sparing of the rectal wall compared to a conventional three-field technique, for patients with a concave-shaped planning target volume (PTV) overlapping the rectal wall. AB - METHODS AND MATERIALS: Five patients have been selected with various degrees of overlap between PTV and rectal wall. The planned dose to the ICRU reference point is 78 Gy. The new technique consists of five beams, each having an open segment covering the entire PTV and several smaller segments in which the rectum is shielded. Segment weights are computer-optimized using an algorithm based on simulated annealing. The score function to be minimized consists of dose-volume constraints for PTV, rectal wall, and femoral heads. The resulting dose distribution is verified for each patient by using point measurements and line scans made with an ionization chamber in a water tank and by using film in a cylindrical polystyrene phantom. AB - RESULTS: The final number of segments in the five-field technique ranges from 7 to 9 after optimization. Compared to the standard three-field technique, the maximum dose to the rectal wall decreases by approximately 3 Gy for patients with a large overlap and 1 Gy for patients with no overlap, resulting in a reduction of the normal tissue complication probability (NTCP) by a factor of 1.3 and 1.2, respectively. The mean dose to the PTV is the same for the two techniques, but the dose distribution is slightly less homogeneous with the five-field technique (Average standard deviation of five patients is 1.1 Gy and 1.7 Gy for the three-field and five-field technique, respectively). Ionization chamber measurements show that in the PTV, the calculated dose is in general within 1% of the measured dose. Outside the PTV, systematic dose deviations of up to 3% exist. Film measurements show that for the complete treatment, the position of the isodose lines in sagittal and coronal planes is calculated fairly accurately, the maximum distance between measured and calculated isodoses being 4 mm. AB - CONCLUSIONS: We developed a relatively simple multisegment "step-and-shoot" technique that can be delivered within an acceptable time frame at the treatment machine (Extra time needed is approximately 3 minutes). The technique results in better sparing of the rectal wall compared to the conventional three-field technique. The technique can be planned and optimized relatively easily using automated procedures and a predefined score function. Dose calculation is accurate and can be verified for each patient individually. IS - 0360-3016 IL - 0360-3016 DI - S0360-3016(00)01525-X PT - Clinical Trial PT - Clinical Trial, Phase III PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 11240262 [pubmed] ID - S0360-3016(00)01525-X [pii] PP - ppublish LG - English DP - 2001 Mar 15 DC - 20010312 EZ - 2001/03/10 10:00 DA - 2001/04/03 10:01 DT - 2001/03/10 10:00 YR - 2001 ED - 20010329 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11240262 <618. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11194701 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - O'Neill HK AU - Gillispie MA AU - Slobin K FA - O'Neill, H K FA - Gillispie, M A FA - Slobin, K IN - O'Neill, H K. Department of Psychology, North Dakota State University in Fargo, P.O. Box 5075, Fargo, North Dakota 58105, USA. TI - Stages of change and smoking cessation: a computer-administered intervention program for young adults. SO - American Journal of Health Promotion. 15(2):93-6, iii, 2000 Nov-Dec AS - Am J Health Promot. 15(2):93-6, iii, 2000 Nov-Dec NJ - American journal of health promotion : AJHP PI - Journal available in: Print PI - Citation processed from: Print JC - amj, 8701680 IO - Am J Health Promot SB - Health Technology Assessment Journals CP - United States MH - Adolescent MH - Adult MH - *Computer-Assisted Instruction/mt [Methods] MH - Female MH - Follow-Up Studies MH - *Health Education/mt [Methods] MH - Health Knowledge, Attitudes, Practice MH - Humans MH - Male MH - Models, Psychological MH - Motivation MH - *Smoking/pc [Prevention & Control] MH - Smoking/px [Psychology] MH - *Smoking Cessation/mt [Methods] MH - Smoking Cessation/px [Psychology] AB - Sixty-five college-student smokers were randomly assigned to a four-week computer-administered, stage-based smoking control program or a four-week computer-administered general health education control condition. At post-test, the percentage of students advancing to a higher stage of readiness to change was slightly higher among those in the stage-based program compared to the control condition. At seven month follow-up, both groups reported abstinence rates of approximately 30%. Continuous abstinence for 6 months was 19% for the stage-based group and 14% for the control group at the final follow-up. IS - 0890-1171 IL - 0890-1171 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial ID - 11194701 [pubmed] PP - ppublish LG - English DP - 2000 Nov-Dec DC - 20010123 EZ - 2001/02/24 12:00 DA - 2001/03/03 10:01 DT - 2001/02/24 12:00 YR - 2000 ED - 20010208 RD - 20041117 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11194701 <619. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 11060584 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kappert U AU - Schneider J AU - Cichon R AU - Gulielmos V AU - Schade I AU - Nicolai J AU - Schueler S FA - Kappert, U FA - Schneider, J FA - Cichon, R FA - Gulielmos, V FA - Schade, I FA - Nicolai, J FA - Schueler, S IN - Kappert, U. Department of Anesthesiology, Cardiovascular Institute, University of Dresden, Fetscherstrasse 76, D-01307 Dresden, Germany. TI - Closed chest totally endoscopic coronary artery bypass surgery: fantasy or reality?. SO - Current Cardiology Reports. 2(6):558-63, 2000 Nov AS - Curr Cardiol Rep. 2(6):558-63, 2000 Nov NJ - Current cardiology reports PI - Journal available in: Print PI - Citation processed from: Print JC - 100888969, dti IO - Curr Cardiol Rep SB - Index Medicus CP - United States MH - Aged MH - Coronary Angiography MH - *Coronary Artery Bypass/mt [Methods] MH - Coronary Artery Bypass/mo [Mortality] MH - Coronary Disease/dg [Diagnostic Imaging] MH - Coronary Disease/mo [Mortality] MH - *Coronary Disease/su [Surgery] MH - *Endoscopy/mt [Methods] MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Minimally Invasive Surgical Procedures/is [Instrumentation] MH - Minimally Invasive Surgical Procedures/mo [Mortality] MH - Prognosis MH - Robotics MH - Sensitivity and Specificity MH - Survival Rate MH - Treatment Outcome AB - With the introduction of the da Vinci robotic surgical system (Intuitive Surgical, Mountain View, CA) into minimally invasive cardiac surgery, the outlook of performing coronary artery bypass operations "closed chest" became a reality. Between May 1999 and July 2000 this wrist-enhanced instrumentation was used in 143 patients (107 men, 36 women, median age 63 10.3 y). Thirteen patients suffering from coronary artery disease (CAD) were treated as totally endoscopic coronary artery bypass (TECAB), 79 patients underwent a minimally invasive direct coronary artery bypass procedure, and 35 patients were treated using the robotic-enhanced Dresden Technique. Preoperative survival was 100%. All patients in the TECAB group were operated upon via a three- or four-point stab incision using the da Vinci robot for internal mammary artery takedown and for performance of anastomoses. These new robotic-enhanced surgical techniques promote an optimistic way of thinking about the further development of these procedures and its application in patients suffering from CAD. IS - 1523-3782 IL - 1523-3782 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 11060584 [pubmed] PP - ppublish LG - English DP - 2000 Nov DC - 20001128 EZ - 2000/11/03 11:00 DA - 2001/02/28 10:01 DT - 2000/11/03 11:00 YR - 2000 ED - 20001128 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11060584 <620. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 10901273 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Smith HR AU - Ashton RE AU - Brooks GJ FA - Smith, H R FA - Ashton, R E FA - Brooks, G J IN - Smith, H R. Department of Dermatology, Royal Hospital Haslar, Gosport, Hampshire, UK. harveyandlucie@hotmail.com TI - Initial use of a computer system for assisting dermatological diagnosis in general practice. SO - Medical Informatics & the Internet in Medicine. 25(2):103-8, 2000 Apr-Jun AS - Med Inform Internet Med. 25(2):103-8, 2000 Apr-Jun NJ - Medical informatics and the Internet in medicine PI - Journal available in: Print PI - Citation processed from: Print JC - 100883495, dcs IO - Med Inform Internet Med SB - Index Medicus CP - England MH - *Diagnosis, Computer-Assisted MH - Diagnosis, Differential MH - *Expert Systems MH - *Family Practice MH - Humans MH - Referral and Consultation MH - *Skin Diseases/di [Diagnosis] AB - The accuracy of skin lesion description by 24 general practitioners was assessed as they used a computer diagnosis assistance system (DERMIS). Descriptive accuracy determines the quality of advice. Only four doctors showed a trend to accurate description over 25 hospital referrals. IS - 1463-9238 IL - 1463-9238 PT - Clinical Trial PT - Journal Article PT - Multicenter Study ID - 10901273 [pubmed] PP - ppublish LG - English DP - 2000 Apr-Jun DC - 20001103 EZ - 2000/07/20 11:00 DA - 2001/02/28 10:01 DT - 2000/07/20 11:00 YR - 2000 ED - 20001121 RD - 20041117 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=10901273 <621. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 10864482 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Rogers DA AU - Regehr G AU - Gelula M AU - Yeh KA AU - Howdieshell TR AU - Webb W FA - Rogers, D A FA - Regehr, G FA - Gelula, M FA - Yeh, K A FA - Howdieshell, T R FA - Webb, W IN - Rogers, D A. Department of Surgery, Medical College of Georgia, Augusta, Georgia 30912-4070, USA. TI - Peer teaching and computer-assisted learning: An effective combination for surgical skill training?. SO - Journal of Surgical Research. 92(1):53-5, 2000 Jul AS - J Surg Res. 92(1):53-5, 2000 Jul NJ - The Journal of surgical research PI - Journal available in: Print PI - Citation processed from: Print JC - k7b, 0376340 IO - J. Surg. Res. SB - Index Medicus CP - United States MH - *Computer-Assisted Instruction MH - Cooperative Behavior MH - *Education, Medical/mt [Methods] MH - *General Surgery/ed [Education] MH - Humans MH - *Peer Group MH - Random Allocation AB - BACKGROUND: The surgical literature suggests that collaborative learning using peers may be a valid way to teach surgical skills and there is a growing interest in the use of computer-assisted learning for this purpose. Combining this evolving technology with this type of teaching would theoretically offer a number of advantages including a reduction in the amount of faculty time devoted to this task. In this study, we evaluate the efficacy of a type of collaborative learning in a computer-assisted learning environment. AB - MATERIALS AND METHODS: We designed a prospective, randomized study comparing novice learners who were allowed to work in pairs with those who worked independently in a specially equipped computer-assisted learning classroom. Both pretest and posttest assessments were performed by videotaping this skill. Three experts then evaluated the videotapes, in a blinded fashion. Three different outcomes were assessed. AB - RESULTS: Seventy-seven subjects were enrolled in and completed the study. Comparison of the outcome measures demonstrated no between group difference in the average performance scores or posttest times. The proportion of subjects who correctly tied a square knot was significantly lower in the computer-assisted peer teaching group when compared with the computer-assisted learning alone group (P = 0.04). AB - CONCLUSIONS: Collaborative learning in a computer-assisted learning environment is not an effective combination for teaching surgical skills to novices. AB - Copyright 2000 Academic Press. IS - 0022-4804 IL - 0022-4804 DI - S0022-4804(00)95844-X DO - https://dx.doi.org/10.1006/jsre.2000.5844 PT - Clinical Trial PT - Controlled Clinical Trial PT - Journal Article ID - 10864482 [pubmed] ID - 10.1006/jsre.2000.5844 [doi] ID - S0022-4804(00)95844-X [pii] PP - ppublish LG - English DP - 2000 Jul DC - 20000724 EZ - 2000/06/23 11:00 DA - 2000/08/01 11:00 DT - 2000/06/23 11:00 YR - 2000 ED - 20000724 RD - 20081121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=10864482 <622. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 10821813 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hundley WG AU - Hillis LD AU - Hamilton CA AU - Applegate RJ AU - Herrington DM AU - Clarke GD AU - Braden GA AU - Thomas MS AU - Lange RA AU - Peshock RM AU - Link KM FA - Hundley, W G FA - Hillis, L D FA - Hamilton, C A FA - Applegate, R J FA - Herrington, D M FA - Clarke, G D FA - Braden, G A FA - Thomas, M S FA - Lange, R A FA - Peshock, R M FA - Link, K M IN - Hundley, W G. Department of Internal Medicine, Wake Forest University Baptist Medical Center, Winston-Salem, NC, USA. ghundley@wfubmc.edu TI - Assessment of coronary arterial restenosis with phase-contrast magnetic resonance imaging measurements of coronary flow reserve. SO - Circulation. 101(20):2375-81, 2000 May 23 AS - Circulation. 101(20):2375-81, 2000 May 23 NJ - Circulation PI - Journal available in: Print PI - Citation processed from: Internet JC - daw, 0147763 IO - Circulation SB - Core Clinical Journals (AIM) SB - Index Medicus SB - National Aeronautics and Space Administration (NASA) Journals CP - United States MH - Adult MH - Aged MH - Blood Flow Velocity MH - Coronary Angiography MH - *Coronary Circulation MH - *Coronary Disease/di [Diagnosis] MH - *Coronary Disease/pp [Physiopathology] MH - *Coronary Vessels/pp [Physiopathology] MH - Diagnosis, Computer-Assisted MH - Female MH - Humans MH - *Magnetic Resonance Imaging/mt [Methods] MH - Male MH - Middle Aged MH - Recurrence AB - BACKGROUND: After successful percutaneous coronary arterial revascularization, 25% to 60% of subjects have restenosis, a recurrent coronary arterial narrowing at the site of the intervention. At present, restenosis is usually detected invasively with contrast coronary angiography. This study was performed to determine if phase-contrast MRI (PC-MRI) could be used to detect restenosis noninvasively in patients with recurrent chest pain after percutaneous revascularization. AB - METHODS AND RESULTS: Seventeen patients (15 men, 2 women, age 36 to 77 years) with recurrent chest pain >3 months after successful percutaneous intervention underwent PC-MRI measurements of coronary artery flow reserve followed by assessments of stenosis severity with computer-assisted quantitative coronary angiography. The intervention was performed in the left anterior descending coronary artery in 15 patients, one of its diagonal branches in 2 patients, and the right coronary artery in 1 patient. A PC-MRI coronary flow reserve value /=70% and >/=50%, respectively. AB - CONCLUSIONS: Assessments of coronary flow reserve with PC-MRI can be used to identify flow-limiting stenoses (luminal diameter narrowings >70%) in patients with recurrent chest pain in the months after a successful percutaneous intervention. ES - 1524-4539 IL - 0009-7322 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 10821813 [pubmed] PP - ppublish LG - English DP - 2000 May 23 DC - 20000621 EZ - 2000/05/24 00:00 DA - 2000/06/24 DT - 2000/05/24 YR - 2000 ED - 20000621 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=10821813 <623. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 10815366 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hetlevik I AU - Holmen J AU - Kruger O AU - Kristensen P AU - Iversen H AU - Furuseth K FA - Hetlevik, I FA - Holmen, J FA - Kruger, O FA - Kristensen, P FA - Iversen, H FA - Furuseth, K IN - Hetlevik, I. National Institute of Public Health, Ranheim Health Center. TI - Implementing clinical guidelines in the treatment of diabetes mellitus in general practice. Evaluation of effort, process, and patient outcome related to implementation of a computer-based decision support system. SO - International Journal of Technology Assessment in Health Care. 16(1):210-27, 2000 Winter AS - Int J Technol Assess Health Care. 16(1):210-27, 2000 Winter NJ - International journal of technology assessment in health care PI - Journal available in: Print PI - Citation processed from: Print JC - gti, 8508113 IO - Int J Technol Assess Health Care SB - Index Medicus CP - England MH - Aged MH - *Decision Support Systems, Clinical MH - *Diabetes Mellitus, Type 1/th [Therapy] MH - *Diabetes Mellitus, Type 2/th [Therapy] MH - Evaluation Studies as Topic MH - Female MH - Humans MH - Male MH - Middle Aged MH - Norway MH - *Outcome and Process Assessment (Health Care) MH - *Practice Guidelines as Topic MH - Practice Patterns, Physicians' AB - OBJECTIVES: To evaluate the implementation of clinical guidelines for diabetes mellitus in general practice with a specific computer-based clinical decision support system (CDSS) as part of the intervention. AB - METHODS: Randomized study with health center as unit. General practice in Sor- and Nord-Trondelag counties in Norway, 380,000 inhabitants. Seventeen health centers with 24 doctors and 499 patients with diabetes mellitus were in the intervention group and 12 health centers with 29 doctors and 535 patients were in the control group. Main outcome measures were group differences in fractions of patients without registrations (process evaluation) and mean group differences for the same variables (patient outcome evaluation). AB - RESULTS: Statistically significant group differences were experienced for fractions of patients without registration of cigarette smoking (intervention group, 82.6%; control group 94.5%), body mass index (78.2% vs. 93.0%), and sufficient registrations for calculation of risk score for myocardial infarction (91.1% vs. 98.3%); all during 18 months. Large center variations were shown for all variables. The only statistically significant group difference was -2.3 mm Hg (95% CI, -3.8, -0.8) in diastolic blood pressure in favor of the intervention group. Statistically insignificant differences in favor of the intervention group were HbA1c, -0.1% (95% CI, -0.4, 0.1), systolic blood pressure, -1.2 mm Hg (95% CI, -4.4, 2.0). Statistically insignificant differences in favor of the control group were fractions of smokers, +3.0% (95% CI, -4.0, 10.0), body mass index, +0.3 kg/m2 (95% CI, -0.8, 1.4), risk score in female +0.1 (95% CI, -5.1, 5.2), and risk score in male +2.6 (95% CI, -14.2, 19.5). AB - CONCLUSIONS: Implementation of clinical guidelines for diabetes mellitus in general practice, by means of a CDSS and several procedures for implementation, did not result in a clinically significant change in doctors' behavior or in patient outcome. IS - 0266-4623 IL - 0266-4623 PT - Clinical Trial PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 10815366 [pubmed] PP - ppublish LG - English DP - 2000 Winter DC - 20000612 EZ - 2000/05/18 09:00 DA - 2000/06/17 09:00 DT - 2000/05/18 09:00 YR - 2000 ED - 20000612 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=10815366 <624. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 10612764 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Damiano RJ Jr AU - Ehrman WJ AU - Ducko CT AU - Tabaie HA AU - Stephenson ER Jr AU - Kingsley CP AU - Chambers CE FA - Damiano, R J Jr FA - Ehrman, W J FA - Ducko, C T FA - Tabaie, H A FA - Stephenson, E R Jr FA - Kingsley, C P FA - Chambers, C E IN - Damiano, R J Jr. Division of Cardiothoracic Surgery, The Milton S. Hershey Medical Center, Hershey, PA, USA. rdamiano@psghs.edu TI - Initial United States clinical trial of robotically assisted endoscopic coronary artery bypass grafting. SO - Journal of Thoracic & Cardiovascular Surgery. 119(1):77-82, 2000 Jan AS - J Thorac Cardiovasc Surg. 119(1):77-82, 2000 Jan NJ - The Journal of thoracic and cardiovascular surgery PI - Journal available in: Print PI - Citation processed from: Print JC - k9j, 0376343 IO - J. Thorac. Cardiovasc. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Anastomosis, Surgical/is [Instrumentation] MH - *Anastomosis, Surgical/mt [Methods] MH - Coronary Artery Bypass/is [Instrumentation] MH - *Coronary Artery Bypass/mt [Methods] MH - Coronary Disease/su [Surgery] MH - *Endoscopy/mt [Methods] MH - Feasibility Studies MH - Female MH - Humans MH - Male MH - Middle Aged MH - Pilot Projects MH - Robotics/is [Instrumentation] MH - *Robotics/mt [Methods] MH - Thoracic Arteries/tr [Transplantation] MH - Treatment Outcome MH - United States MH - Vascular Patency AB - OBJECTIVES: With traditional instruments, endoscopic coronary artery bypass grafting has not been possible. This study was designed to determine the clinical feasibility of using a robotically assisted microsurgical system to create endoscopic coronary anastomoses. AB - METHODS AND RESULTS: Ten patients underwent endoscopic coronary artery bypass grafting of the left internal thoracic artery to the left anterior descending artery. Subxiphoid endoscopic ports (2 for instruments, 1 for a camera) were placed, and a robotic system was used to perform the left internal thoracic artery-left anterior descending artery bypass graft. Conventional techniques were used to perform the other grafts. Blood flow through the left internal thoracic artery graft was measured in the operating room and was adequate in 8 of 10 patients. The 2 inadequate grafts were revised successfully by hand. Six weeks after the operation, selective coronary angiography demonstrated a graft patency of 100% (8/8). There were no technical failures of the robotic system. The only postoperative complication was mediastinal hemorrhage in 1 patient. AB - CONCLUSIONS: This pilot study demonstrates the feasibility of robotically assisted endoscopic coronary artery bypass grafting. IS - 0022-5223 IL - 0022-5223 DI - S002252230028762X PT - Clinical Trial PT - Journal Article ID - 10612764 [pubmed] ID - S002252230028762X [pii] PP - ppublish LG - English DP - 2000 Jan DC - 20000217 EZ - 1999/12/29 09:00 DA - 2000/02/19 09:00 DT - 1999/12/29 09:00 YR - 2000 ED - 20000217 RD - 20140728 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=10612764 <625. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 10631376 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Caversaccio M AU - Bachler R AU - Ladrach K AU - Schroth G AU - Nolte LP AU - Hausler R FA - Caversaccio, M FA - Bachler, R FA - Ladrach, K FA - Schroth, G FA - Nolte, L P FA - Hausler, R IN - Caversaccio, M. Department of Otorhinolaryngology, Head and Neck Surgery, University of Bern, Bern, Switzerland. TI - The "Bernese" frameless optical computer aided surgery system. SO - Computer Aided Surgery. 4(6):328-34, 1999 AS - Comput Aided Surg. 4(6):328-34, 1999 NJ - Computer aided surgery : official journal of the International Society for Computer Aided Surgery PI - Journal available in: Print PI - Citation processed from: Print JC - cuk, 9708375 IO - Comput. Aided Surg. SB - Index Medicus CP - England MH - Cadaver MH - Humans MH - *Paranasal Sinuses/dg [Diagnostic Imaging] MH - *Paranasal Sinuses/su [Surgery] MH - *Skull/dg [Diagnostic Imaging] MH - *Skull/su [Surgery] MH - Switzerland MH - *Therapy, Computer-Assisted MH - *Tomography, X-Ray Computed AB - OBJECTIVE: We report on two years of clinical experience with a frameless Computer Aided Surgery system developed in Bern, Switzerland. AB - MATERIAL AND METHODS: Our navigation system is based on a preoperative computer-tomography (CT) scan (without markers) and an intraoperative optical tracking of head movements and of the surgical instruments. Using landmark and surface-based registration, the skull can be accurately correlated to the CT images. The three-dimensional positions of the surgical instruments, as well as the endoscopic images, are displayed in real time on a monitor. AB - RESULTS: In the last two years, 109 computer-aided interventions have been successfully performed: 89 on the anterior skull base/paranasal sinuses, 15 on the lateral skull base, and 5 minimally invasive procedures on other locations in the skull. No complications occurred. The practical accuracy on the cadaver skull is between 0.5 mm and 1.2 mm, and the clinical accuracy is between 0. 5 mm and 2 mm. AB - CONCLUSIONS: Our navigation system has proven its accuracy and usability. Surgeons feel very comfortable with the increased safety provided by the unequivocal identification of important anatomical structures. AB - Copyright 1999 Wiley-Liss, Inc. IS - 1092-9088 IL - 1092-9088 DI - 10.1002/(SICI)1097-0150(1999)4:6<328::AID-IGS5>3.0.CO;2-Y DO - https://dx.doi.org/10.1002/(SICI)1097-0150(1999)4:6<328::AID-IGS5>3.0.CO;2-Y PT - Clinical Trial PT - Journal Article ID - 10631376 [pubmed] ID - 10.1002/(SICI)1097-0150(1999)4:6<328::AID-IGS5>3.0.CO;2-Y [pii] ID - 10.1002/(SICI)1097-0150(1999)4:6<328::AID-IGS5>3.0.CO;2-Y [doi] PP - ppublish LG - English DP - 1999 DC - 20000217 EZ - 2000/01/13 09:00 DA - 2000/02/19 09:00 DT - 2000/01/13 09:00 YR - 1999 ED - 20000217 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=10631376 <626. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 10600428 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Bonevski B AU - Sanson-Fisher RW AU - Campbell E AU - Carruthers A AU - Reid AL AU - Ireland M FA - Bonevski, B FA - Sanson-Fisher, R W FA - Campbell, E FA - Carruthers, A FA - Reid, A L FA - Ireland, M IN - Bonevski, B. New South Wales Cancer Council, Cancer Education Research Program (CERP), Locked Bag 10, Wallsend, New South Wales, 2287, Australia. billieb@mail.newcastle.edu.au TI - Randomized controlled trial of a computer strategy to increase general practitioner preventive care. SO - Preventive Medicine. 29(6 Pt 1):478-86, 1999 Dec AS - Prev Med. 29(6 Pt 1):478-86, 1999 Dec NJ - Preventive medicine PI - Journal available in: Print PI - Citation processed from: Print JC - pm4, 0322116 IO - Prev Med SB - Index Medicus CP - United States MH - Adult MH - Attitude of Health Personnel MH - *Computer-Assisted Instruction/mt [Methods] MH - *Education, Medical, Continuing/mt [Methods] MH - *Family Practice/ed [Education] MH - Female MH - Health Behavior MH - Humans MH - Logistic Models MH - Male MH - Mass Screening MH - New South Wales MH - Odds Ratio MH - Practice Guidelines as Topic MH - *Preventive Medicine/ed [Education] MH - Risk Factors MH - Sensitivity and Specificity AB - BACKGROUND: Previous interventions targeting primary care practitioners with the aim of increasing preventive care delivery have demonstrated limited effectiveness. The primary aim of this study was to assess the effectiveness of a computerized continuing medical education program to increase rates of three screening behaviors (cholesterol, blood pressure, and cervical screening) and to identify three risk behaviors (smoking, alcohol consumption, benzodiazepine use) in general practice. AB - METHODS: Nineteen general practitioners were randomly allocated to intervention or control conditions. Those given the intervention received a computerized feedback system. The intervention was delivered using a touch-screen computer located in the surgery waiting area. The preventive behaviors of interest were patient smoking, alcohol use, benzodiazepine use, and blood pressure, cholesterol and cervical screening using the Papanicolou test. Differences in performance by group in each of the outcomes was measured at baseline and 3-month follow-up. Logistic regression analyses with generalized estimating equations were conducted as the main analyses. AB - RESULT: At 3-month follow-up, statistically significant differences were evident in the following outcome measures: accurate classification of benzodiazepine users (z = 2.8540, P < 0.05); accurate classification of non-benzodiazepine users (z = 2.7339, P < 0.05); accurate classification of hazardous or harmful alcohol drinkers (z = 2.3079, P < 0.02); blood pressure screening (z = 3.4136, P < 0.001); and cholesterol screening (z = 6.6313, P < 0.001). AB - CONCLUSION: A computerized system of performance-specific feedback was effective at increasing some preventive care services in general practice. AB - Copyright 1999 American Health Foundation and Academic Press. IS - 0091-7435 IL - 0091-7435 DI - S0091-7435(99)90567-4 DO - https://dx.doi.org/10.1006/pmed.1999.0567 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 10600428 [pubmed] ID - 10.1006/pmed.1999.0567 [doi] ID - S0091-7435(99)90567-4 [pii] PP - ppublish LG - English DP - 1999 Dec DC - 20000124 EZ - 1999/12/22 00:00 DA - 1999/12/22 00:01 DT - 1999/12/22 YR - 1999 ED - 20000124 RD - 20071115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=10600428 <627. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 10550090 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Jones R AU - Pearson J AU - McGregor S AU - Cawsey AJ AU - Barrett A AU - Craig N AU - Atkinson JM AU - Gilmour WH AU - McEwen J FA - Jones, R FA - Pearson, J FA - McGregor, S FA - Cawsey, A J FA - Barrett, A FA - Craig, N FA - Atkinson, J M FA - Gilmour, W H FA - McEwen, J IN - Jones, R. Department of Public Health, University of Glasgow, Glasgow G12 8RZ. r.b.jones@udcf.gla.ac.uk TI - Randomised trial of personalised computer based information for cancer patients. CM - Comment in: BMJ. 2000 Jul 1;321(7252):47-8; PMID: 10939814 CM - Comment in: BMJ. 2000 Jul 1;321(7252):48; PMID: 10939815 CM - Comment in: BMJ. 2000 Apr 29;320(7243):1212; PMID: 10784562 SO - BMJ. 319(7219):1241-7, 1999 Nov 06 AS - BMJ. 319(7219):1241-7, 1999 Nov 06 NJ - BMJ (Clinical research ed.) PI - Journal available in: Print PI - Citation processed from: Print JC - 8900488, bmj, 101090866 IO - BMJ PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC28275 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - Attitude to Computers MH - Computers/ec [Economics] MH - Costs and Cost Analysis MH - Data Collection MH - Databases as Topic/ec [Economics] MH - *Databases as Topic/ut [Utilization] MH - Humans MH - Medical Informatics/ec [Economics] MH - *Neoplasms/th [Therapy] MH - *Patient Education as Topic/mt [Methods] MH - Patient Satisfaction AB - OBJECTIVE: To compare the use and effect of a computer based information system for cancer patients that is personalised using each patient's medical record with a system providing only general information and with information provided in booklets. AB - DESIGN: Randomised trial with three groups. Data collected at start of radiotherapy, one week later (when information provided), three weeks later, and three months later. AB - PARTICIPANTS: 525 patients started radical radiotherapy; 438 completed follow up. AB - INTERVENTIONS: Two groups were offered information via computer (personalised or general information, or both) with open access to computer thereafter; the third group was offered a selection of information booklets. AB - OUTCOMES: Patients' views and preferences, use of computer and information, and psychological status; doctors' perceptions; cost of interventions. AB - RESULTS: More patients offered the personalised information said that they had learnt something new, thought the information was relevant, used the computer again, and showed their computer printouts to others. There were no major differences in doctors' perceptions of patients. More of the general computer group were anxious at three months. With an electronic patient record system, in the long run the personalised information system would cost no more than the general system. Full access to booklets cost twice as much as the general system. AB - CONCLUSIONS: Patients preferred computer systems that provided information from their medical records to systems that just provided general information. This has implications for the design and implementation of electronic patient record systems and reliance on general sources of patient information. IS - 0959-8138 IL - 0959-535X PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 10550090 [pubmed] ID - PMC28275 [pmc] PP - ppublish LG - English DP - 1999 Nov 06 DC - 19991217 EZ - 1999/11/05 00:00 DA - 1999/11/05 00:01 DT - 1999/11/05 YR - 1999 ED - 19991217 RD - 20140615 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=10550090 <628. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 10525488 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hundley WG AU - Hamilton CA AU - Thomas MS AU - Herrington DM AU - Salido TB AU - Kitzman DW AU - Little WC AU - Link KM FA - Hundley, W G FA - Hamilton, C A FA - Thomas, M S FA - Herrington, D M FA - Salido, T B FA - Kitzman, D W FA - Little, W C FA - Link, K M IN - Hundley, W G. Cardiology Section, Division of Radiological Sciences, The Wake Forest University School of Medicine, Winston-Salem, NC, USA. ghundley@wfubmc.edu TI - Utility of fast cine magnetic resonance imaging and display for the detection of myocardial ischemia in patients not well suited for second harmonic stress echocardiography. CM - Comment in: Circulation. 1999 Oct 19;100(16):1676-9; PMID: 10525484 SO - Circulation. 100(16):1697-702, 1999 Oct 19 AS - Circulation. 100(16):1697-702, 1999 Oct 19 NJ - Circulation PI - Journal available in: Print PI - Citation processed from: Internet JC - daw, 0147763 IO - Circulation SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adrenergic beta-Agonists/ad [Administration & Dosage] MH - Adult MH - Aged MH - Aged, 80 and over MH - Atropine/ad [Administration & Dosage] MH - Coronary Angiography MH - Disease-Free Survival MH - Dobutamine/ad [Administration & Dosage] MH - Echocardiography/de [Drug Effects] MH - *Echocardiography MH - Electrocardiography MH - *Exercise Test/ae [Adverse Effects] MH - Exercise Test/de [Drug Effects] MH - Female MH - Heart Rate/de [Drug Effects] MH - Humans MH - Infusions, Intravenous MH - Magnetic Resonance Imaging/ae [Adverse Effects] MH - *Magnetic Resonance Imaging MH - Male MH - Middle Aged MH - *Myocardial Ischemia/di [Diagnosis] MH - Myocardial Ischemia/dg [Diagnostic Imaging] MH - Myocardial Ischemia/mo [Mortality] MH - Myocardial Ischemia/pp [Physiopathology] MH - Patient Selection AB - BACKGROUND: Some patients referred for pharmacological stress testing with transthoracic echocardiography (TTE) are unable to undergo testing owing to poor acoustic windows. Fast cine MRI can be used to assess left ventricular contraction, but its utility for detection of myocardial ischemia in patients poorly suited for echocardiography is unknown. AB - METHODS AND RESULTS: One hundred fifty-three patients (86 men and 67 women aged 30 to 88 years) with poor acoustic windows that prevented adequate second harmonic TTE imaging were consecutively referred for MRI to diagnose inducible myocardial ischemia during intravenous dobutamine and atropine. Diagnostic studies were completed in an average of 53 minutes. No patients experienced myocardial infarction, ventricular fibrillation, exacerbation of congestive heart failure, or death. In patients who underwent computer-assisted quantitative coronary angiography, the sensitivity and specificity for detecting a >50% luminal diameter narrowing were 83% and 83%, respectively. In the 103 patients with a negative MRI examination, the cardiovascular occurrence-free survival rate was 97%. AB - CONCLUSIONS: Fast cine cardiac MRI provides a mechanism to assess left ventricular contraction and diagnose inducible myocardial ischemia in patients not well suited for stress echocardiography. RN - 0 (Adrenergic beta-Agonists) RN - 3S12J47372 (Dobutamine) RN - 7C0697DR9I (Atropine) ES - 1524-4539 IL - 0009-7322 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 10525488 [pubmed] PP - ppublish LG - English DP - 1999 Oct 19 DC - 19991123 EZ - 1999/10/20 00:00 DA - 1999/10/20 00:01 DT - 1999/10/20 YR - 1999 ED - 19991123 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=10525488 <629. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 10522120 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tai SS AU - Nazareth I AU - Donegan C AU - Haines A FA - Tai, S S FA - Nazareth, I FA - Donegan, C FA - Haines, A IN - Tai, S S. Department of Primary Care and Population Sciences, Royal Free and University College Medical School, University College London, UK. TI - Evaluation of general practice computer templates. Lessons from a pilot randomised controlled trial. SO - Methods of Information in Medicine. 38(3):177-81, 1999 Sep AS - Methods Inf Med. 38(3):177-81, 1999 Sep NJ - Methods of information in medicine PI - Journal available in: Print PI - Citation processed from: Print JC - mvi, 0210453 IO - Methods Inf Med SB - Index Medicus CP - Germany MH - *Asthma/th [Therapy] MH - *Decision Support Systems, Clinical MH - *Diabetes Mellitus/th [Therapy] MH - *Family Practice MH - *Guideline Adherence MH - Humans MH - London MH - Office Nursing MH - Pilot Projects MH - *Practice Guidelines as Topic AB - We conducted a pilot randomised trial of computerised templates for the management of asthma and diabetes in general practice in six general practices in North London. Uptake of the guidelines by general practitioners and practice nurses was assessed using qualitative (semi-structured interviews designed to assess the users' views) and quantitative (change in use of the template during the study period) outcome measures. The practice nurses used the templates frequently but general practitioners rarely used them. Several reasons were offered for non-use of the templates, such as the length of the template and non-involvement in the care of asthma or diabetes. Despite this, however, health professionals were favourably disposed to the use of templates for general clinical care. Pilot investigations of computerised templates are best achieved by observational or quasi-experimental methods rather than a randomised controlled trial. The use of both qualitative and quantitative methods in this study allowed exploration of the barriers to use of computers. IS - 0026-1270 IL - 0026-1270 DI - 99030177 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 99030177 [pii] PP - ppublish LG - English DP - 1999 Sep DC - 19991027 EZ - 1999/10/16 00:00 DA - 1999/10/16 00:01 DT - 1999/10/16 YR - 1999 ED - 19991027 RD - 20170410 UP - 20170412 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=10522120 <630. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 10522120 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tai SS AU - Nazareth I AU - Donegan C AU - Haines A FA - Tai, S S FA - Nazareth, I FA - Donegan, C FA - Haines, A IN - Tai, S S. Department of Primary Care and Population Sciences, Royal Free and University College Medical School, University College London, UK. TI - Evaluation of general practice computer templates. Lessons from a pilot randomised controlled trial. SO - Methods of Information in Medicine. 38(3):177-81, 1999 Sep AS - Methods Inf Med. 38(3):177-81, 1999 Sep NJ - Methods of information in medicine PI - Journal available in: Print PI - Citation processed from: Print JC - mvi, 0210453 IO - Methods Inf Med SB - Index Medicus CP - Germany MH - *Asthma/th [Therapy] MH - *Decision Support Systems, Clinical MH - *Diabetes Mellitus/th [Therapy] MH - *Family Practice MH - *Guideline Adherence MH - Humans MH - London MH - Office Nursing MH - Pilot Projects MH - *Practice Guidelines as Topic AB - We conducted a pilot randomised trial of computerised templates for the management of asthma and diabetes in general practice in six general practices in North London. Uptake of the guidelines by general practitioners and practice nurses was assessed using qualitative (semi-structured interviews designed to assess the users' views) and quantitative (change in use of the template during the study period) outcome measures. The practice nurses used the templates frequently but general practitioners rarely used them. Several reasons were offered for non-use of the templates, such as the length of the template and non-involvement in the care of asthma or diabetes. Despite this, however, health professionals were favourably disposed to the use of templates for general clinical care. Pilot investigations of computerised templates are best achieved by observational or quasi-experimental methods rather than a randomised controlled trial. The use of both qualitative and quantitative methods in this study allowed exploration of the barriers to use of computers. IS - 0026-1270 IL - 0026-1270 DI - 99030177 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 10522120 [pubmed] ID - 99030177 [pii] PP - ppublish LG - English DP - 1999 Sep DC - 19991027 EZ - 1999/10/16 00:00 DA - 1999/10/16 00:01 DT - 1999/10/16 YR - 1999 ED - 19991027 RD - 20071115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=10522120 <631. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 10455902 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Summers AN AU - Rinehart GC AU - Simpson D AU - Redlich PN FA - Summers, A N FA - Rinehart, G C FA - Simpson, D FA - Redlich, P N IN - Summers, A N. Department of Surgery (Plastic Surgery and General Surgery), Medical College of Wisconsin, Milwaukee, USA. TI - Acquisition of surgical skills: a randomized trial of didactic, videotape, and computer-based training. SO - Surgery. 126(2):330-6, 1999 Aug AS - Surgery. 126(2):330-6, 1999 Aug NJ - Surgery PI - Journal available in: Print PI - Citation processed from: Print JC - vc3, 0417347 IO - Surgery SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - *Clinical Competence MH - *Computer-Assisted Instruction MH - *General Surgery/ed [Education] MH - Humans MH - Prospective Studies AB - BACKGROUND: Although computer-based training (CBT) can enhance didactic instruction, few studies have assessed the efficacy of CBT for basic surgical skills training. This study compares CBT with traditional methods of basic surgical skills training. AB - METHODS: Sixty-nine naive medical students were randomized into 3 treatment groups for basic surgical skills instruction: didactic, videotape, or CBT. All instructional material contained the same pictures, text, and audio. With use of a multiple-choice question examination and a series of performance stations, students were objectively assessed before, immediately after, and 1 month after skills instruction. Raters were blinded to treatment modality during the follow-up evaluation. AB - RESULTS: There were no significant differences among the groups before treatment. After treatment, the didactic group scored higher on the multiple-choice question examination. In contrast, the videotape and CBT groups demonstrated statistically significant (P < .01) enhancement of technical skills compared with the didactic group. After 1 month, a calculated performance quotient revealed statistically significant (P < .01) improvement only in the CBT group. The amount of time students spent practicing their skills was not significantly different among the groups. AB - CONCLUSIONS: CBT is as effective as, and possibly more efficient, than traditional methods of basic surgical skills training for medical students. IS - 0039-6060 IL - 0039-6060 DI - S0039606099001981 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 10455902 [pubmed] ID - S0039606099001981 [pii] PP - ppublish LG - English DP - 1999 Aug DC - 19990902 EZ - 1999/08/24 00:00 DA - 1999/08/24 00:01 DT - 1999/08/24 YR - 1999 ED - 19990902 RD - 20081121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=10455902 <632. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 10396907 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Howard MA 3rd AU - Abkes BA AU - Ollendieck MC AU - Noh MD AU - Ritter RC AU - Gillies GT FA - Howard, M A 3rd FA - Abkes, B A FA - Ollendieck, M C FA - Noh, M D FA - Ritter, R C FA - Gillies, G T IN - Howard, M A 3rd. Division of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City 52242, USA. TI - Measurement of the force required to move a neurosurgical probe through in vivo human brain tissue. SO - IEEE Transactions on Biomedical Engineering. 46(7):891-4, 1999 Jul AS - IEEE Trans Biomed Eng. 46(7):891-4, 1999 Jul NJ - IEEE transactions on bio-medical engineering PI - Journal available in: Print PI - Citation processed from: Print JC - gfx, 0012737 IO - IEEE Trans Biomed Eng SB - Index Medicus CP - United States MH - Biomechanical Phenomena MH - *Brain/su [Surgery] MH - Catheterization MH - Epilepsy/su [Surgery] MH - Equipment Design MH - Friction MH - Humans MH - Neurosurgery/is [Instrumentation] MH - *Neurosurgery/mt [Methods] MH - Robotics MH - *Stereotaxic Techniques MH - *Therapy, Computer-Assisted AB - The advent of high-precision magnetic and robotic computer-controlled neurosurgery systems makes it necessary to determine the range of forces that will be encountered by the probes of such devices as they are guided through the brain tissues to intraparenchymal targets. We have measured the penetration forces on 2.5-mm spheres and the drag forces on 3.0-mm ventricular shunt catheters advanced 2.0-3.5 cm deep into in vivo human brain tissues (in patients about to have those tissues resected during epilepsy surgery) at rates of approximately 0.33 mm s-1. Penetration forces of (8 +/- 2) grams were found for the spherical probe once it passed 0.5 cm below the cortical surface, and frictional drags of (2.8 +/- 0.3) grams cm-1 were exerted on the catheters. The variable nature of these forces is discussed and the results are compared with earlier studies on experimental animal tissues and brain phantom gelatins. The implications of these results for magnetic and robotic surgery systems are considered. IS - 0018-9294 IL - 0018-9294 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 10396907 [pubmed] PP - ppublish LG - English DP - 1999 Jul DC - 19990728 EZ - 1999/07/09 10:00 DA - 2001/03/28 10:01 DT - 1999/07/09 10:00 YR - 1999 ED - 19990728 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=10396907 <633. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 10407535 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Motohashi N AU - Kuroda T FA - Motohashi, N FA - Kuroda, T IN - Motohashi, N. Second Department of Orthodontics, Faculty of Dentistry, Tokyo Medical and Dental University, Japan. TI - A 3D computer-aided design system applied to diagnosis and treatment planning in orthodontics and orthognathic surgery. SO - European Journal of Orthodontics. 21(3):263-74, 1999 Jun AS - Eur J Orthod. 21(3):263-74, 1999 Jun NJ - European journal of orthodontics PI - Journal available in: Print PI - Citation processed from: Print JC - eos, 7909010 IO - Eur J Orthod SB - Dental Journals SB - Index Medicus CP - England MH - Algorithms MH - Cleft Palate/pa [Pathology] MH - *Computer Graphics MH - *Computer-Aided Design MH - *Dental Models MH - Diagnosis, Computer-Assisted MH - Feasibility Studies MH - Humans MH - Image Processing, Computer-Assisted MH - Lasers MH - *Malocclusion/di [Diagnosis] MH - Malocclusion/th [Therapy] MH - Reproducibility of Results AB - The purpose of this article is to describe a newly developed 3D computer-aided design (CAD) system for the diagnostic set-up of casts in orthodontic diagnosis and treatment planning, and its preliminary clinical applications. The system comprises a measuring unit which obtains 3D information from the dental model using laser scanning, and a personal computer to generate the 3D graphics. When measuring the 3D shape of the model, to minimize blind sectors, the model is scanned from two different directions with the slit-ray laser beam by rotating the mounting angle of the model on the measuring device. For computed simulation of tooth movement, the representative planes, defined by the anatomical reference points, are formed for each individual tooth and are arranged along a guideline descriptive of the individual arch form. Subsequently, the 3D shape is imparted to each of the teeth arranged on the representative plane to form an arrangement of the 3D profile. When necessary, orthognathic surgery can be simulated by moving the mandibular dental arch three-dimensionally to establish the optimum occlusal relationship. Compared with hand-made set-up models, the computed diagnostic cast has advantages such as high-speed processing and quantitative evaluation on the amount of 3D movement of the individual tooth relative to the craniofacial plane. Trial clinical applications demonstrated that the use of this system facilitated the otherwise complicated and time-consuming mock surgery for treatment planning in orthognathic surgery. IS - 0141-5387 IL - 0141-5387 PT - Clinical Trial PT - Journal Article ID - 10407535 [pubmed] PP - ppublish LG - English DP - 1999 Jun DC - 19990720 EZ - 1999/07/17 00:00 DA - 1999/07/17 00:01 DT - 1999/07/17 YR - 1999 ED - 19990720 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=10407535 <634. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 10229991 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hetlevik I AU - Holmen J AU - Kruger O FA - Hetlevik, I FA - Holmen, J FA - Kruger, O IN - Hetlevik, I. National Institute of Public Health, Community Medicine Research Unit, Verdal, Norway. TI - Implementing clinical guidelines in the treatment of hypertension in general practice. Evaluation of patient outcome related to implementation of a computer-based clinical decision support system. CM - Comment in: Scand J Prim Health Care. 2000 Mar;18(1):61-3; PMID: 10811048 SO - Scandinavian Journal of Primary Health Care. 17(1):35-40, 1999 Mar AS - Scand J Prim Health Care. 17(1):35-40, 1999 Mar NJ - Scandinavian journal of primary health care PI - Journal available in: Print PI - Citation processed from: Print JC - 8510679, sif IO - Scand J Prim Health Care SB - Index Medicus CP - United States MH - *Decision Making, Computer-Assisted MH - *Family Practice MH - Female MH - Humans MH - *Hypertension/th [Therapy] MH - Male MH - Middle Aged MH - Norway MH - *Practice Guidelines as Topic AB - OBJECTIVE: To evaluate the implementation of clinical guidelines for hypertension in general practice by use of a computer-based clinical decision support system (CDSS) and a specific implementation strategy. Evaluation of patient outcome. AB - DESIGN: Randomised study with health centres as units. The intervention group had the CDSS installed and made ready for use, doctors and assistants were trained and received a user-manual, the doctors were offered telephone repetitions, a seminar in risk intervention and, at the same seminar, further demonstration of the CDSS. The doctors received baseline registrations with information of how they treated their own hypertensive patients, and use of the CDSS was checked repeatedly. AB - SETTING: General practice in Sor- and Nord-Trondelag counties in Norway, 380,000 inhabitants. AB - PARTICIPANTS: Seventeen health centres with 24 doctors and 984 patients in the intervention group. Data from 879 patients used in the final analyses. Twelve health centres with 29 doctors and 1255 patients in the control group. Data from 1119 patients used in the final analyses. AB - MAIN OUTCOME MEASURES: After an intervention period of 18 months, group differences in level of systolic and diastolic blood pressure, serum cholesterol, body mass index, and risk score for myocardial infarction were calculated, as well as group differences in fractions of smokers. AB - RESULTS: Significant group difference in favour of intervention group: diastolic blood pressure 1 mmHg (95% CI -1.89, -0.17). However, a significant baseline difference in systolic blood pressure in favour of control group of 2.7 mmHg (95% CI 1.0, 4.5) had been reduced to 1.2 mmHg (95% CI -0.6, 3.0) after intervention. AB - CONCLUSION: Implementation of clinical guidelines in the treatment of hypertensive patients in general practice by means of a CDSS and several other procedures for implementation did not affect patient outcome in any clinically significant way. IS - 0281-3432 IL - 0281-3432 PT - Clinical Trial PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 10229991 [pubmed] PP - ppublish LG - English DP - 1999 Mar DC - 19990623 EZ - 1999/05/07 00:00 DA - 1999/05/07 00:01 DT - 1999/05/07 YR - 1999 ED - 19990623 RD - 20071115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=10229991 <635. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9793701 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Gobel H AU - Heinze A AU - Kuhn K AU - Heuss D AU - Lindner V FA - Gobel, H FA - Heinze, A FA - Kuhn, K FA - Heuss, D FA - Lindner, V IN - Gobel, H. Neurologisch-verhaltensmedizinische Schmerzklinik Kiel, Germany. TI - Effect of operationalized computer diagnosis on the therapeutic results of sumatriptan in general practice. CM - Comment in: Cephalalgia. 1998 Sep;18(7):419-20; PMID: 9793693 SO - Cephalalgia. 18(7):481-6, 1998 Sep AS - Cephalalgia. 18(7):481-6, 1998 Sep NJ - Cephalalgia : an international journal of headache PI - Journal available in: Print PI - Citation processed from: Print JC - cqp, 8200710 IO - Cephalalgia SB - Index Medicus CP - England MH - Adolescent MH - Adult MH - *Algorithms MH - *Diagnosis, Computer-Assisted MH - Family Practice MH - Female MH - Humans MH - Male MH - Middle Aged MH - Migraine Disorders/di [Diagnosis] MH - *Migraine Disorders/dt [Drug Therapy] MH - Serotonin Receptor Agonists/ae [Adverse Effects] MH - *Serotonin Receptor Agonists/tu [Therapeutic Use] MH - Sumatriptan/ae [Adverse Effects] MH - *Sumatriptan/tu [Therapeutic Use] MH - Treatment Outcome AB - A multicenter test was conducted to investigate the effectiveness of the selective serotonin agonist sumatriptan in patients with the computerized headache diagnosis of migraine. A computer program was used for diagnostic evaluation of patients attending a general practice because of headache. The results of the analysis were taken as a direct decision on therapy. If the patients satisfied the criteria for migraine, they were given subcutaneous sumatriptan for treating three migraine attacks. The patients were able to use the study medication under outpatient conditions. The therapeutic efficacy of the medicine was recorded in a headache diary. A total of 91 patients were included in the study at 22 practices in Germany. An average of four patients per practice were recruited. In the first migraine attack treated, headache improvement was experienced by 77.7% of the patients treated. In the second and third attacks an improvement was experienced by 93.5% and 89.8%, respectively. The results show that by optimizing diagnostic reliability with the aid of the computer program a high response rate can be achieved under practice conditions using the selective serotonin agonist sumatriptan. Since the computer program described permits a specific diagnosis, it improves the prospects of effective headache therapy in the individual patient. Thus treatment based on this approach can reduce inputs of time and money in migraine therapy. RN - 0 (Serotonin Receptor Agonists) RN - 8R78F6L9VO (Sumatriptan) IS - 0333-1024 IL - 0333-1024 DO - https://dx.doi.org/10.1111/j.1468-2982.1998.1807481.x PT - Clinical Trial PT - Controlled Clinical Trial PT - Journal Article PT - Multicenter Study ID - 9793701 [pubmed] ID - 10.1111/j.1468-2982.1998.1807481.x [doi] PP - ppublish LG - English DP - 1998 Sep DC - 19990107 EZ - 1998/10/30 00:00 DA - 1998/10/30 00:01 DT - 1998/10/30 YR - 1998 ED - 19990107 RD - 20170214 UP - 20170215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=9793701 <636. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9793701 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Gobel H AU - Heinze A AU - Kuhn K AU - Heuss D AU - Lindner V FA - Gobel, H FA - Heinze, A FA - Kuhn, K FA - Heuss, D FA - Lindner, V IN - Gobel, H. Neurologisch-verhaltensmedizinische Schmerzklinik Kiel, Germany. TI - Effect of operationalized computer diagnosis on the therapeutic results of sumatriptan in general practice. CM - Comment in: Cephalalgia. 1998 Sep;18(7):419-20; PMID: 9793693 SO - Cephalalgia. 18(7):481-6, 1998 Sep AS - Cephalalgia. 18(7):481-6, 1998 Sep NJ - Cephalalgia : an international journal of headache PI - Journal available in: Print PI - Citation processed from: Print JC - cqp, 8200710 IO - Cephalalgia SB - Index Medicus CP - England MH - Adolescent MH - Adult MH - *Algorithms MH - *Diagnosis, Computer-Assisted MH - Family Practice MH - Female MH - Humans MH - Male MH - Middle Aged MH - Migraine Disorders/di [Diagnosis] MH - *Migraine Disorders/dt [Drug Therapy] MH - Serotonin Receptor Agonists/ae [Adverse Effects] MH - *Serotonin Receptor Agonists/tu [Therapeutic Use] MH - Sumatriptan/ae [Adverse Effects] MH - *Sumatriptan/tu [Therapeutic Use] MH - Treatment Outcome AB - A multicenter test was conducted to investigate the effectiveness of the selective serotonin agonist sumatriptan in patients with the computerized headache diagnosis of migraine. A computer program was used for diagnostic evaluation of patients attending a general practice because of headache. The results of the analysis were taken as a direct decision on therapy. If the patients satisfied the criteria for migraine, they were given subcutaneous sumatriptan for treating three migraine attacks. The patients were able to use the study medication under outpatient conditions. The therapeutic efficacy of the medicine was recorded in a headache diary. A total of 91 patients were included in the study at 22 practices in Germany. An average of four patients per practice were recruited. In the first migraine attack treated, headache improvement was experienced by 77.7% of the patients treated. In the second and third attacks an improvement was experienced by 93.5% and 89.8%, respectively. The results show that by optimizing diagnostic reliability with the aid of the computer program a high response rate can be achieved under practice conditions using the selective serotonin agonist sumatriptan. Since the computer program described permits a specific diagnosis, it improves the prospects of effective headache therapy in the individual patient. Thus treatment based on this approach can reduce inputs of time and money in migraine therapy. RN - 0 (Serotonin Receptor Agonists) RN - 8R78F6L9VO (Sumatriptan) IS - 0333-1024 IL - 0333-1024 PT - Clinical Trial PT - Controlled Clinical Trial PT - Journal Article PT - Multicenter Study ID - 9793701 [pubmed] PP - ppublish LG - English DP - 1998 Sep DC - 19990107 EZ - 1998/10/30 00:00 DA - 1998/10/30 00:01 DT - 1998/10/30 YR - 1998 ED - 19990107 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9793701 <637. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9819579 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ormerod TC AU - Richardson J AU - Shepherd A FA - Ormerod, T C FA - Richardson, J FA - Shepherd, A IN - Ormerod, T C. Department of Psychology, Lancaster University, UK. TI - Enhancing the usability of a task analysis method: a notation and environment for requirements specification. SO - Ergonomics. 41(11):1642-63, 1998 Nov AS - Ergonomics. 41(11):1642-63, 1998 Nov NJ - Ergonomics PI - Journal available in: Print PI - Citation processed from: Print JC - 0373220, elz IO - Ergonomics SB - Index Medicus SB - National Aeronautics and Space Administration (NASA) Journals CP - England MH - Computers MH - Humans MH - Semantics MH - Software Design MH - *Task Performance and Analysis AB - This paper presents a notation and computer-based tool for the Sub-Goal Template (SGT) method, a task-analytic approach to specifying information requirements. In particular, it focuses upon the ergonomic redesign of a notation used in the SGT method for specifying contingent sequences in operators' tasks. Two experiments are reported in which two notations for redescribing sequences that involve making a choice between task alternatives are compared: a disjunctive form (Either ... or ...)-used in the original SGT scheme, and a conditional form with a redundant negative (If ... then ... if not ...), which has been promoted as a notation for capturing procedural sequences in computer programming. In experiment 1, performance with the conditional notation was better than with the disjunctive notation for redescribing simple and moderately complex task plans, although there was no difference for the most complex task plans. In experiment 2, a computer environment for specifying task plans using the SGT method was compared with a paper-based equivalent. In general, the computer environment was found to be easier to use and led to greater accuracy in plan redescription, although it was slower perhaps as a result of the constraints that it placed on participants. This paper argues for the necessity of ergonomic design in developing notations and tools to support task analysis methods. IS - 0014-0139 IL - 0014-0139 DO - https://dx.doi.org/10.1080/001401398186117 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 9819579 [pubmed] ID - 10.1080/001401398186117 [doi] PP - ppublish LG - English DP - 1998 Nov DC - 19981203 EZ - 1998/11/20 00:00 DA - 1998/11/20 00:01 DT - 1998/11/20 YR - 1998 ED - 19981203 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9819579 <638. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9808805 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lowensteyn I AU - Joseph L AU - Levinton C AU - Abrahamowicz M AU - Steinert Y AU - Grover S FA - Lowensteyn, I FA - Joseph, L FA - Levinton, C FA - Abrahamowicz, M FA - Steinert, Y FA - Grover, S IN - Lowensteyn, I. Centre for the Analysis of Cost-Effective Care and the Divisions of General Internal Medicine and Clinical Epidemiology, The Montreal General Hospital, Quebec, Vanada, H3G 1A4. TI - Can computerized risk profiles help patients improve their coronary risk? The results of the Coronary Health Assessment Study (CHAS). SO - Preventive Medicine. 27(5 Pt 1):730-7, 1998 Sep-Oct AS - Prev Med. 27(5 Pt 1):730-7, 1998 Sep-Oct NJ - Preventive medicine PI - Journal available in: Print PI - Citation processed from: Print JC - pm4, 0322116 IO - Prev Med SB - Index Medicus CP - United States MH - Adult MH - Coronary Disease/et [Etiology] MH - *Coronary Disease/pc [Prevention & Control] MH - *Decision Making, Computer-Assisted MH - *Decision Support Techniques MH - Family Practice/ed [Education] MH - *Family Practice/mt [Methods] MH - Feasibility Studies MH - Female MH - *Health Status Indicators MH - Humans MH - Likelihood Functions MH - Male MH - Middle Aged MH - *Primary Prevention/mt [Methods] MH - Risk Factors AB - BACKGROUND: The Coronary Health Assessment Study (CHAS) was developed to determine the feasibility of using patient-specific, multifactorial computerized coronary risk profiles as a clinical decision aid to support primary prevention of CHD. AB - METHODS: Study participants included 253 community based physicians, randomized into profile and control groups, and 958 of their patients. The profile group physicians received coronary risk profiles for their patients within 10 working days after the baseline patient assessment providing early feedback. The control group received their profiles only if the patient was clinically reevaluated during a 3-month follow-up visit. Patients' coronary risk factors were evaluated at baseline and at follow-up. AB - RESULTS: The profile group had a significantly higher (P < 0.05) ratio of high-risk/low-risk patients who returned for a follow-up visit compared to the control group (1.23 vs 0.77). The patients in the profile group also had significantly (P < 0.05) greater mean reductions in total cholesterol (-0.5 vs -0.1 mmol/L), LDL cholesterol (-0.4 vs 0.0 mmol/L), the total cholesterol/ HDL ratio (-0.6 vs -0.2), and the predicted 8-year coronary risk (-1.8 vs -0.3%). AB - CONCLUSIONS: Computer-generated coronary risk profiles can be effective in assisting physicians to identify high-risk patients. Their use is also associated with significantly greater improvements in the serum lipid profiles and the overall coronary risk of these patients. AB - Copyright 1998 American Health Foundation and Academic Press. IS - 0091-7435 IL - 0091-7435 DI - S0091-7435(98)90351-6 DO - https://dx.doi.org/10.1006/pmed.1998.0351 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 9808805 [pubmed] ID - S0091-7435(98)90351-6 [pii] ID - 10.1006/pmed.1998.0351 [doi] PP - ppublish LG - English DP - 1998 Sep-Oct DC - 19981130 EZ - 1998/11/11 00:00 DA - 1998/11/11 00:01 DT - 1998/11/11 YR - 1998 ED - 19981130 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9808805 <639. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9690108 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Brug J AU - Glanz K AU - Van Assema P AU - Kok G AU - van Breukelen GJ FA - Brug, J FA - Glanz, K FA - Van Assema, P FA - Kok, G FA - van Breukelen, G J IN - Brug, J. Department of Social Studies, Open University, DL Heerlen, The Netherlands. TI - The impact of computer-tailored feedback and iterative feedback on fat, fruit, and vegetable intake. SO - Health Education & Behavior. 25(4):517-31, 1998 Aug AS - Health Educ Behav. 25(4):517-31, 1998 Aug NJ - Health education & behavior : the official publication of the Society for Public Health Education PI - Journal available in: Print PI - Citation processed from: Print JC - cql, 9704962 IO - Health Educ Behav SB - Index Medicus CP - United States MH - Adult MH - *Dietary Fats/ad [Administration & Dosage] MH - *Feedback MH - Feeding Behavior/px [Psychology] MH - *Feeding Behavior MH - Female MH - *Fruit MH - Health Knowledge, Attitudes, Practice MH - Humans MH - Male MH - Middle Aged MH - Netherlands MH - Nutritional Requirements MH - Nutritional Sciences/ed [Education] MH - Self Efficacy MH - *Software MH - Surveys and Questionnaires MH - *Vegetables AB - A randomized trial was conducted to study the impact of individualized computer-generated nutrition information and additional effects of iterative feedback on changes in intake of fat, fruits, and vegetables. Respondents in the experimental group received computer-generated feedback letters tailored to their dietary intake, intentions, attitudes, self-efficacy expectations, and self-rated behavior. After the first feedback letter, half of the experimental group received additional iterative feedback tailored to changes in behavior and intentions. The control group received a single general nutrition information letter in a format similar to the tailored letters. Computer-tailored feedback had a significantly greater impact on fat reduction and fruit and vegetable intake than did general information. Iterative computer-tailored feedback had an additional impact on fat intake. The results confirm that computer-generated individualized feedback can be effective in inducing recommended dietary changes and that iterative feedback can increase the longer term impact of computer-tailored nutrition education on fat reduction. RN - 0 (Dietary Fats) IS - 1090-1981 IL - 1090-1981 DO - https://dx.doi.org/10.1177/109019819802500409 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 9690108 [pubmed] ID - 10.1177/109019819802500409 [doi] PP - ppublish LG - English DP - 1998 Aug DC - 19981112 EZ - 1998/08/05 00:00 DA - 1998/08/05 00:01 DT - 1998/08/05 YR - 1998 ED - 19981112 RD - 20170214 UP - 20170215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=9690108 <640. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9690108 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Brug J AU - Glanz K AU - Van Assema P AU - Kok G AU - van Breukelen GJ FA - Brug, J FA - Glanz, K FA - Van Assema, P FA - Kok, G FA - van Breukelen, G J IN - Brug, J. Department of Social Studies, Open University, DL Heerlen, The Netherlands. TI - The impact of computer-tailored feedback and iterative feedback on fat, fruit, and vegetable intake. SO - Health Education & Behavior. 25(4):517-31, 1998 Aug AS - Health Educ Behav. 25(4):517-31, 1998 Aug NJ - Health education & behavior : the official publication of the Society for Public Health Education PI - Journal available in: Print PI - Citation processed from: Print JC - cql, 9704962 IO - Health Educ Behav SB - Index Medicus CP - United States MH - Adult MH - *Dietary Fats/ad [Administration & Dosage] MH - *Feedback MH - Feeding Behavior/px [Psychology] MH - *Feeding Behavior MH - Female MH - *Fruit MH - Health Knowledge, Attitudes, Practice MH - Humans MH - Male MH - Middle Aged MH - Netherlands MH - Nutritional Requirements MH - Nutritional Sciences/ed [Education] MH - Self Efficacy MH - *Software MH - Surveys and Questionnaires MH - *Vegetables AB - A randomized trial was conducted to study the impact of individualized computer-generated nutrition information and additional effects of iterative feedback on changes in intake of fat, fruits, and vegetables. Respondents in the experimental group received computer-generated feedback letters tailored to their dietary intake, intentions, attitudes, self-efficacy expectations, and self-rated behavior. After the first feedback letter, half of the experimental group received additional iterative feedback tailored to changes in behavior and intentions. The control group received a single general nutrition information letter in a format similar to the tailored letters. Computer-tailored feedback had a significantly greater impact on fat reduction and fruit and vegetable intake than did general information. Iterative computer-tailored feedback had an additional impact on fat intake. The results confirm that computer-generated individualized feedback can be effective in inducing recommended dietary changes and that iterative feedback can increase the longer term impact of computer-tailored nutrition education on fat reduction. RN - 0 (Dietary Fats) IS - 1090-1981 IL - 1090-1981 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 9690108 [pubmed] PP - ppublish LG - English DP - 1998 Aug DC - 19981112 EZ - 1998/08/05 00:00 DA - 1998/08/05 00:01 DT - 1998/08/05 YR - 1998 ED - 19981112 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9690108 <641. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9685532 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Danis J FA - Danis, J IN - Danis, J. Surgical Department, General Public Hospital, Austria. TI - The effect of contrast variation on task performance in video evaluation. SO - Surgical Endoscopy. 12(8):1013-6, 1998 Aug AS - Surg Endosc. 12(8):1013-6, 1998 Aug NJ - Surgical endoscopy PI - Journal available in: Print PI - Citation processed from: Print JC - vbf, 8806653 IO - Surg Endosc SB - Index Medicus CP - Germany MH - Adipose Tissue/ah [Anatomy & Histology] MH - Adipose Tissue/pa [Pathology] MH - Cholecystectomy, Laparoscopic/is [Instrumentation] MH - *Cholecystectomy, Laparoscopic/mt [Methods] MH - Contrast Media/me [Metabolism] MH - Evaluation Studies as Topic MH - Gallbladder/ah [Anatomy & Histology] MH - Gallbladder/pa [Pathology] MH - Humans MH - *Image Enhancement/mt [Methods] MH - Light MH - Liver/ah [Anatomy & Histology] MH - Liver/pa [Pathology] MH - Robotics/mt [Methods] MH - Sensitivity and Specificity MH - Spectrophotometry MH - Task Performance and Analysis MH - *Video Recording/mt [Methods] AB - BACKGROUND: Luminosity and brightness of the organs viewed on the screen are important for orientation during teleoperating. They can impair the precision of our orientation ability. AB - METHODS: The way in which organs scatter light during laparoscopic operation was detected and analyzed by means of reflection spectrophotometry with the Photoshop program package (ADOBE). The arithmetical skill was measured during different illumination conditions of the screen created randomly, using values of the liver, gallbladder, and omental fat. AB - RESULTS: Separate human tissues and organs could be divided on the basis of their luminosity into three basic groups: the luminous tissues such as fat, the stomach, and the bowel; medium-luminous organs such as diaphragm and gallbladder; and dark, mostly parenchymatous organs such as the liver and the spleen. The most luminous tissue illuminated the screen intensely. In experiments the hyperillumination impaired arithmetical skills of 15 volunteers. The errors appeared constantly and the time needed to count the generated points was significantly longer when 40% of intensively illuminated view was exceeded. AB - CONCLUSIONS: A situation may occur wherein the imaging system lacks the capacity to transmit needed optical information. Intense brightness of the screen may suppress surgical skills during teleoperating. Critical limit was achieved in our experiment with 40% of the view illuminated by omentum fat. This limit can be important for robotic surgical systems such as automated robotic camera control. RN - 0 (Contrast Media) IS - 0930-2794 IL - 0930-2794 PT - Clinical Trial PT - Journal Article ID - 9685532 [pubmed] PP - ppublish LG - English DP - 1998 Aug DC - 19981022 EZ - 1998/08/01 00:00 DA - 1998/08/01 00:01 DT - 1998/08/01 YR - 1998 ED - 19981022 RD - 20071115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9685532 <642. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9606783 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Rorvik J AU - Halvorsen OJ AU - Albrektsen G AU - Haukaas S FA - Rorvik, J FA - Halvorsen, O J FA - Albrektsen, G FA - Haukaas, S IN - Rorvik, J. Department of Radiology, Gade Institute, Norway. TI - Lymphangiography combined with biopsy and computer tomography to detect lymph node metastases in localized prostate cancer. SO - Scandinavian Journal of Urology & Nephrology. 32(2):116-9, 1998 Apr AS - Scand J Urol Nephrol. 32(2):116-9, 1998 Apr NJ - Scandinavian journal of urology and nephrology PI - Journal available in: Print PI - Citation processed from: Print JC - uda, 0114501 IO - Scand. J. Urol. Nephrol. SB - Index Medicus CP - England MH - Aged MH - Biopsy, Needle MH - Evaluation Studies as Topic MH - Humans MH - *Lymphatic Metastasis/di [Diagnosis] MH - Lymphography MH - Male MH - Middle Aged MH - *Neoplasm Staging/mt [Methods] MH - Predictive Value of Tests MH - Prospective Studies MH - *Prostatic Neoplasms/di [Diagnosis] MH - Sensitivity and Specificity MH - Tomography, X-Ray Computed AB - To evaluate the efficacy of lymphangiography combined with fine needle aspiration biopsy and computer tomography (CT) for lymph node staging in clinically localized prostate cancer. Prospective evaluation of nodal involvement was carried out using standard bipedal lymphangiography combined with fine needle aspiration biopsy (FNAB) in 70 patients (aged 47 to 75 years, mean age 63 years) with apparently locally confined prostate cancer before intended radical prostatectomy. Sixty-four patients also underwent computer tomography. Seventeen withdrew the decision to undergo a radical prostatectomy, leaving 53 patients with pathologic examination of the lymph nodes eligible for analysis. Lymph node metastases were diagnosed in 8 patients (8/53 = 15.1%). Three were diagnosed preoperatively by FNAB, 3 peroperatively by lymph node dissection and frozen section biopsy and an additional 2 at the final pathologic assessment. The sensitivity, specificity, positive and negative predictive values for lymphangiography and lymphangiography combined with FNAB in predicting nodal disease, based on the analysis of the 53 patients with known pathologic results, were 0.63, 0.76, 0.31, 0.92 and 0.38, 1.00, 1.00, 0.90, respectively. The corresponding values for CT staging were 0.25, 0.98, 0.67 and 0.87, respectively. The efficacy of bipedal lymphangiography alone or combined with FNAB or CT alone for assessment of nodal metastases is too low to be worthwhile for lymph node staging in localized prostate cancer patients with expected low or intermediate probability of nodal disease. IS - 0036-5599 IL - 0036-5599 PT - Clinical Trial PT - Journal Article ID - 9606783 [pubmed] PP - ppublish LG - English DP - 1998 Apr DC - 19980716 EZ - 1998/06/02 00:00 DA - 1998/06/02 00:01 DT - 1998/06/02 YR - 1998 ED - 19980716 RD - 20071115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9606783 <643. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9645783 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Rogers DA AU - Regehr G AU - Yeh KA AU - Howdieshell TR FA - Rogers, D A FA - Regehr, G FA - Yeh, K A FA - Howdieshell, T R IN - Rogers, D A. Department of Surgery, Medical College of Georgia, Augusta 30912-4070, USA. TI - Computer-assisted learning versus a lecture and feedback seminar for teaching a basic surgical technical skill. SO - American Journal of Surgery. 175(6):508-10, 1998 Jun AS - Am J Surg. 175(6):508-10, 1998 Jun NJ - American journal of surgery PI - Journal available in: Print PI - Citation processed from: Print JC - 3z4, 0370473 IO - Am. J. Surg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - *Computer-Assisted Instruction MH - *Education, Medical, Undergraduate MH - *General Surgery/ed [Education] MH - Humans MH - Prospective Studies MH - Random Allocation MH - Suture Techniques MH - *Teaching/mt [Methods] MH - Videotape Recording AB - BACKGROUND: Rapid improvements in computer technology allow us to consider the use of computer-assisted learning (CAL) for teaching technical skills in surgical training. The objective of this study was to compare in a prospective, randomized fashion, CAL with a lecture and feedback seminar (LFS) for the purpose of teaching a basic surgical skill. AB - METHODS: Freshman medical students were randomly assigned to spend 1 hour in either a CAL or LFS session. Both sessions were designed to teach them to tie a two-handed square knot. Students in both groups were given knot tying boards and those in the CAL group were asked to interact with the CAL program. Students in the LFS group were given a slide presentation and were given individualized feedback as they practiced this skill. At the end of the session the students were videotaped tying two complete knots. The tapes were independently analyzed, in a blinded fashion, by three surgeons. The total time for the task was recorded, the knots were evaluated for squareness, and each subject was scored for the quality of performance. AB - RESULTS: Data from 82 subjects were available for the final analysis. Comparison of the two groups demonstrated no significant difference between the proportion of subjects who were able to tie a square knot. There was no difference between the average time required to perform the task. The CAL group had significantly lower quality of performance (t = 5.37, P <0.0001). AB - CONCLUSIONS: CAL and LFS were equally effective in conveying the cognitive information associated with this skill. However, the significantly lower performance score demonstrates that the students in the CAL group did not attain a proficiency in this skill equal to the students in the LFS group. Comments by the students suggest that the lack of feedback in this model of CAL was the significant difference between these two educational methods. IS - 0002-9610 IL - 0002-9610 DI - S0002961098000877 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 9645783 [pubmed] ID - S0002961098000877 [pii] PP - ppublish LG - English DP - 1998 Jun DC - 19980709 EZ - 1998/06/30 00:00 DA - 1998/06/30 00:01 DT - 1998/06/30 YR - 1998 ED - 19980709 RD - 20081121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9645783 <644. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9611930 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kellett J FA - Kellett, J TI - The impact of a bedside decision support computer program (DSCP) on coronary care. SO - Irish Medical Journal. 90(6):240, 1997 Oct AS - Ir Med J. 90(6):240, 1997 Oct NJ - Irish medical journal PI - Journal available in: Print PI - Citation processed from: Print JC - gxd, 0430275 IO - Ir Med J SB - Index Medicus CP - Ireland MH - Critical Care MH - *Diagnosis, Computer-Assisted MH - *Fibrinolytic Agents/ad [Administration & Dosage] MH - Humans MH - Ireland MH - *Myocardial Infarction/di [Diagnosis] MH - *Myocardial Infarction/dt [Drug Therapy] MH - Myocardial Infarction/mo [Mortality] MH - *Point-of-Care Systems MH - Sensitivity and Specificity MH - *Streptokinase/ad [Administration & Dosage] MH - Survival Rate MH - Treatment Outcome RN - 0 (Fibrinolytic Agents) RN - EC 3-4 (Streptokinase) IS - 0332-3102 IL - 0332-3102 PT - Clinical Trial PT - Comparative Study PT - Letter ID - 9611930 [pubmed] PP - ppublish LG - English DP - 1997 Oct DC - 19980630 EZ - 1998/06/05 00:00 DA - 1998/06/05 00:01 DT - 1998/06/05 YR - 1997 ED - 19980630 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9611930 <645. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9550501 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hunninghake DB FA - Hunninghake, D B IN - Hunninghake, D B. Heart Disease Prevention Clinic, The University of Minnesota, Minneapolis 55455, USA. TI - Therapeutic efficacy of the lipid-lowering armamentarium: the clinical benefits of aggressive lipid-lowering therapy. SO - American Journal of Medicine. 104(2A):9S-13S, 1998 Feb 23 AS - Am J Med. 104(2A):9S-13S, 1998 Feb 23 NJ - The American journal of medicine PI - Journal available in: Print PI - Citation processed from: Print JC - 0267200, 3ju IO - Am. J. Med. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - *Anticholesteremic Agents/tu [Therapeutic Use] MH - *Cholesterol, LDL/bl [Blood] MH - Coronary Angiography MH - *Coronary Artery Bypass MH - Coronary Disease/bl [Blood] MH - Coronary Disease/dg [Diagnostic Imaging] MH - *Coronary Disease/dt [Drug Therapy] MH - Coronary Disease/et [Etiology] MH - *Coronary Disease/pc [Prevention & Control] MH - Coronary Disease/su [Surgery] MH - Disease Progression MH - Double-Blind Method MH - Humans MH - *Hydroxymethylglutaryl-CoA Reductase Inhibitors/tu [Therapeutic Use] MH - Hypercholesterolemia/bl [Blood] MH - Hypercholesterolemia/co [Complications] MH - *Hypercholesterolemia/dt [Drug Therapy] MH - Treatment Outcome AB - Hypercholesterolemia, particularly an elevated level of low-density lipoprotein (LDL) cholesterol, is an unarguably established risk factor for coronary artery disease (CAD). It is equally well established that lowering LDL cholesterol levels will decrease CAD-related morbidity and mortality in patients with established CAD. Although lipid-lowering therapy is known to retard the progression of atherosclerosis in patients with native coronary arteries, its effect in patients with coronary bypass grafts, which are particularly vulnerable to occlusion, is less well understood. Moreover, whereas several major clinical trials have documented the benefits of lowering LDL cholesterol in a variety of patient subpopulations, there has been far less clarity surrounding the question of whether aggressive lowering of LDL cholesterol is of greater benefit than moderate lowering of LDL cholesterol. The Post Coronary Artery Bypass Graft (Post-CABG) trial, a multicenter, randomized, double-blind clinical trial comprising 1,351 patients with elevated levels of LDL cholesterol and a history of bypass surgery was designed to determine whether aggressive lowering of LDL cholesterol levels with therapy based on 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors ("statins") is more effective than moderate lowering in delaying the progression of atherosclerosis in bypass grafts. Quantitative computer-assisted angiography was conducted at baseline and again at an average of 4.3 years. The primary angiographic outcome was the mean percentage per patient of grafts with a decrease of > or = 0.6 mm in lumen diameter. Patients who received aggressive therapy were significantly more likely than their moderate-treatment counterparts to achieve and maintain LDL cholesterol levels within the National Cholesterol Education Program's (NCEP's) recommended target of < or = 100 mg/dL (< or = 2.59 mmol/L). Moreover, the mean percentage of grafts with progression of atherosclerosis was 27% for aggressively treated patients, compared with 39% for those who were randomized to the moderate-treatment group (p < 0.001). This study demonstrates that aggressive lipid lowering is practical and worthwhile in at-risk patients. Aggressive treatment is far more effective than moderate treatment in lowering LDL cholesterol levels to the NCEP target level of < or = 100 mg/dL (< or = 2.59 mmol/L), and this intervention decreases the progression of atherosclerosis. RN - 0 (Anticholesteremic Agents) RN - 0 (Cholesterol, LDL) RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) IS - 0002-9343 IL - 0002-9343 PT - Clinical Trial PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial ID - 9550501 [pubmed] PP - ppublish LG - English DP - 1998 Feb 23 DC - 19980422 EZ - 1998/04/29 00:00 DA - 1998/04/29 00:01 DT - 1998/04/29 YR - 1998 ED - 19980422 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9550501 <646. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9421649 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Singer PS AU - Hopper KD AU - Jozefiak JA AU - Patrone SV AU - Kasales CJ AU - Mahraj RP AU - Tenhave TR AU - Tully DA FA - Singer, P S FA - Hopper, K D FA - Jozefiak, J A FA - Patrone, S V FA - Kasales, C J FA - Mahraj, R P FA - Tenhave, T R FA - Tully, D A IN - Singer, P S. Department of Radiology, Penn State University, Hershey, PA 17033, USA. TI - Extended pitch thoracic helical CT 47. SO - Clinical Imaging. 22(1):11-4, 1998 Jan-Feb AS - Clin Imaging. 22(1):11-4, 1998 Jan-Feb NJ - Clinical imaging PI - Journal available in: Print PI - Citation processed from: Print JC - cim, 8911831 IO - Clin Imaging SB - Index Medicus CP - United States MH - Contrast Media MH - Humans MH - Image Processing, Computer-Assisted/mt [Methods] MH - Lung/dg [Diagnostic Imaging] MH - Lung Diseases/dg [Diagnostic Imaging] MH - Radiographic Image Enhancement/mt [Methods] MH - Sensitivity and Specificity MH - Tomography, X-Ray Computed/mt [Methods] MH - *Tomography, X-Ray Computed AB - The objective of this study was to test whether extended 1.5 pitch helical computed tomography (CT) can be used for routine thoracic CT without a significant loss of clinical scan quality. Thirty consecutive patients presenting for contrast thoracic CT were computer randomized into one of three groups: conventional, 1.0 pitch helical, and 1.5 pitch helical. All other variables, including kV, mA, slice thickness and reconstruction interval, and contrast administration, were kept constant. The studies were randomized to five independent, blinded, experienced radiologists who rated visualization 25 normal structures, and up to five pathologic findings per patient. In addition, each reader evaluated the studies' contrast enhancement, low contrast sensitivity, linear resolution, motion artifact, noise, and overall quality. The visualization score for all normal and overall for pathological lesions did not vary between groups. The three groups were not equivalent for several individual pathologic categories. However, these differences were not consistently in favor of one technique over the other two. The overall score for scan quality was not significantly different between the three groups. Extended 1.5 pitch thoracic helical CT provides equivalent quality versus either 1.0 pitch helical or conventional CT. The use of 1.5 pitch helical thoracic CT allows faster scanning, greater patient coverage, and the use of reduced amounts of intravenous contrast. RN - 0 (Contrast Media) IS - 0899-7071 IL - 0899-7071 DI - S0899707197000648 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 9421649 [pubmed] ID - S0899707197000648 [pii] PP - ppublish LG - English DP - 1998 Jan-Feb DC - 19980210 EZ - 1998/01/09 00:00 DA - 1998/01/09 00:01 DT - 1998/01/09 YR - 1998 ED - 19980210 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9421649 <647. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9415087 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Elves AW AU - Ahmed M AU - Abrams P FA - Elves, A W FA - Ahmed, M FA - Abrams, P IN - Elves, A W. Bristol Urological Institute, Southmead Hospital, Westbury-on-Trym, UK. TI - Computer-assisted learning; experience at the Bristol Urological Institute in the teaching of urology. SO - British Journal of Urology. 80 Suppl 3:59-62, 1997 Nov AS - Br J Urol. 80 Suppl 3:59-62, 1997 Nov NJ - British journal of urology PI - Journal available in: Print PI - Citation processed from: Print JC - b3k, 15740090r IO - Br J Urol SB - Index Medicus CP - England MH - Adult MH - *Computer-Assisted Instruction MH - *Education, Medical, Undergraduate MH - England MH - Female MH - Humans MH - Male MH - *Urology/ed [Education] AB - OBJECTIVE: To report the use of a computer-assisted learning (CAL) program in the teaching of urology to medical students. AB - SUBJECTS AND METHODS: Four CAL tutorials were developed, covering the examination of the urological patient, prostate cancer, impotence and lower urinary tract symptoms, for an initial evaluation of the use of CAL. Twenty-six third-year medical students seconded to the department for one week of urology teaching were randomized to two equal groups. One group used the CAL programs in addition to daily formal teaching, while the other group only received daily teaching. Teaching was of a standardized format, covering all aspects of urology, including the four areas covered by the CAL tutorials. Students were assessed using standardized multiple-choice questions (MCQ) at the start and end of the week's teaching. Incorrect responses were marked negatively. The content and ease of use of the CAL programs were also evaluated by a questionnaire. AB - RESULTS: There was no difference between the groups in MCQ scores at the start of the week. The mean (SD) change in score over the week for those using the CAL tutorials was 6.0 (7.0), and for the control group was 0.9 (6.0), a significant difference (P < 0.005). Students reported the tutorials to be easy to use and of satisfactory content. AB - CONCLUSION: The results of this study suggest that CAL programs are of benefit to students learning urology. IS - 0007-1331 IL - 0007-1331 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 9415087 [pubmed] PP - ppublish LG - English DP - 1997 Nov DC - 19980113 EZ - 1998/02/12 00:00 DA - 1998/02/12 00:01 DT - 1998/02/12 YR - 1997 ED - 19980113 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9415087 <648. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9366778 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hirschl MM AU - Binder M AU - Gwechenberger M AU - Herkner H AU - Bur A AU - Kittler H AU - Laggner AN FA - Hirschl, M M FA - Binder, M FA - Gwechenberger, M FA - Herkner, H FA - Bur, A FA - Kittler, H FA - Laggner, A N IN - Hirschl, M M. Department of Emergency Medicine, University of Vienna, New General Hospital, Austria. TI - Noninvasive assessment of cardiac output in critically ill patients by analysis of the finger blood pressure waveform. CM - Comment in: Crit Care Med. 1999 Aug;27(8):1693-4; PMID: 10470804 CM - Comment in: Crit Care Med. 1997 Nov;25(11):1783-4; PMID: 9366756 SO - Critical Care Medicine. 25(11):1909-14, 1997 Nov AS - Crit Care Med. 25(11):1909-14, 1997 Nov NJ - Critical care medicine PI - Journal available in: Print PI - Citation processed from: Print JC - dtf, 0355501 IO - Crit. Care Med. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Aged, 80 and over MH - *Blood Pressure MH - Blood Pressure Determination/mt [Methods] MH - *Cardiac Output MH - Computer Systems MH - Critical Care MH - Emergency Service, Hospital MH - Female MH - Fingers/bs [Blood Supply] MH - Fingers/ph [Physiology] MH - Humans MH - Male MH - Middle Aged MH - *Monitoring, Physiologic/mt [Methods] MH - Pulse MH - Signal Processing, Computer-Assisted MH - Software MH - Thermodilution AB - OBJECTIVE: To assess whether the measurement of cardiac output by computer-assisted analysis of the finger blood pressure waveform can substitute for the thermodilution method in critically ill patients. AB - DESIGN: Prospective data collection. AB - SETTING: Emergency department in a 2000-bed inner city hospital AB - PATIENTS: Forty-six critically ill patients requiring invasive monitoring for clinical management were prospectively studied. AB - INTERVENTIONS: Under local anesthesia a 7-Fr pulmonary artery catheter was inserted via the central subclavian or jugular vein. Cardiac output was determined by the use of a cardiac output computer and injections of 10 mL ice-cold glucose 5%. Noninvasive cardiac output was calculated from the finger blood pressure waveform by the use of the test software program. AB - MEASUREMENTS AND MAIN RESULTS: Three hundred twenty-three pairs of invasive and noninvasive hemodynamic measurements were collected in intervals of 30 mins from 46 patients (mean age 61.9 +/- 12.4 yrs; 35 male, 11 female). The average cardiac index during the study period was 2.83 L/min/m2 (range 0.97 to 5.56). The overall discrepancy between both measurements was 0.14 L/min/m2 (95% confidence interval: 0.10-.018, p < .001). Seventy-five (23.2%) measurements had an absolute discrepancy > +/- 0.50 L/min/m2. Noninvasive and invasive comparisons of mean differential cardiac output were out of phase for 9.7% of all readings. AB - CONCLUSION: Computer-assisted analysis of finger blood pressure waveform to assess cardiac output is not a substitute for the thermodilution method due to a high percentage (23.2%) of inaccurate readings; however, it may be a useful tool for the detection of relative hemodynamic trends in critically ill patients. IS - 0090-3493 IL - 0090-3493 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 9366778 [pubmed] PP - ppublish LG - English DP - 1997 Nov DC - 19971209 EZ - 1997/11/21 00:00 DA - 1997/11/21 00:01 DT - 1997/11/21 YR - 1997 ED - 19971209 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9366778 <649. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9356083 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Monk TG AU - Goodnough LT AU - Brecher ME AU - Pulley DD AU - Colberg JW AU - Andriole GL AU - Catalona WJ FA - Monk, T G FA - Goodnough, L T FA - Brecher, M E FA - Pulley, D D FA - Colberg, J W FA - Andriole, G L FA - Catalona, W J IN - Monk, T G. Department of Anesthesia, Washington University School of Medicine, St. Louis, Missouri 63110, USA. monkt@notes.wustl.edu TI - Acute normovolemic hemodilution can replace preoperative autologous blood donation as a standard of care for autologous blood procurement in radical prostatectomy. CM - Comment in: Anesth Analg. 1998 Jul;87(1):233-4; PMID: 9661586 SO - Anesthesia & Analgesia. 85(5):953-8, 1997 Nov AS - Anesth Analg. 85(5):953-8, 1997 Nov NJ - Anesthesia and analgesia PI - Journal available in: Print PI - Citation processed from: Print JC - 4r8, 1310650 IO - Anesth. Analg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - *Blood Donors MH - *Blood Transfusion, Autologous MH - *Hemodilution/mt [Methods] MH - Humans MH - Male MH - Middle Aged MH - Preoperative Care MH - *Prostatectomy AB - UNLABELLED: Predonation of autologous blood (PAD) is a standard of care for patients undergoing radical prostatectomy, but recent studies have shown that PAD is not cost-effective. Acute normovolemic hemodilution (ANH) is an alternative autologous blood procurement technique that is much less costly than PAD. We compared the efficacy and costs of ANH alone to ANH combined with PAD. Two hundred-fifty patients who predonated fewer than 3 units of autologous blood before radical prostatectomy underwent ANH to a target hematocrit of 28%. Perioperative hematocrit levels, transfusion outcomes and costs, and postoperative outcomes were compared for patients who predonated 0, 1, or 2 units of blood before surgery. A computer model was used to estimate the savings in red blood cells (RBC) associated with each autologous intervention. ANH alone resulted in a 21% allogeneic transfusion rate and contributed a mean net savings of 112 mL RBC in blood conservation (equivalent to 0.6 unit of blood). The addition of 1 or 2 units of PAD reduced allogeneic exposure rates to 6% or 0%, respectively. Overall, patients who predonated blood had a mean net loss of 198 mL of RBC (equivalent to 1 blood unit), due to both an absence in compensatory erythropoiesis and to the wastage of 60% of the blood units donated. Patients who underwent ANH alone had a 60% reduction in mean total transfusion costs ($103 +/- $102) compared with patients who predeposited 2 units of autologous blood in addition to ANH ($269 +/- $11, P < 0.05). We conclude that ANH can replace PAD as an autologous blood option because it is less costly and equally effective. A combination of ANH and PAD can further decrease allogeneic blood exposure, but it increases transfusion costs and wastage. AB - IMPLICATIONS: A patient's own blood can be obtained for use in surgery by predonation or acute normovolemic hemodilution on the day of surgery. Both blood collection techniques decrease the need for blood bank transfusions, but acute normovolemic hemodilution is less expensive and more convenient for patients. IS - 0003-2999 IL - 0003-2999 PT - Clinical Trial PT - Journal Article ID - 9356083 [pubmed] PP - ppublish LG - English DP - 1997 Nov DC - 19971128 EZ - 1997/11/14 00:00 DA - 1997/11/14 00:01 DT - 1997/11/14 YR - 1997 ED - 19971128 RD - 20130520 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9356083 <650. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9345174 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Walton RT AU - Gierl C AU - Yudkin P AU - Mistry H AU - Vessey MP AU - Fox J FA - Walton, R T FA - Gierl, C FA - Yudkin, P FA - Mistry, H FA - Vessey, M P FA - Fox, J IN - Walton, R T. Department of Public Health and Primary Care, Radcliffe Infirmary, Oxford. robert.walton@public-health.oxford.ac.uk TI - Evaluation of computer support for prescribing (CAPSULE) using simulated cases. SO - BMJ. 315(7111):791-5, 1997 Sep 27 AS - BMJ. 315(7111):791-5, 1997 Sep 27 NJ - BMJ (Clinical research ed.) PI - Journal available in: Print PI - Citation processed from: Print JC - 8900488, bmj, 101090866 IO - BMJ PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2127529 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - *Decision Making, Computer-Assisted MH - Drug Costs MH - Drug Prescriptions/ec [Economics] MH - Drug Prescriptions/sn [Statistics & Numerical Data] MH - *Drug Utilization Review MH - Family Practice/ec [Economics] MH - *Family Practice/og [Organization & Administration] MH - Humans MH - London MH - Outcome Assessment (Health Care) MH - Patient Simulation MH - Practice Patterns, Physicians' AB - OBJECTIVE: To evaluate the potential effect of computer support on general practitioners' prescribing, and to compare the effectiveness of three different support levels. AB - DESIGN: Crossover experiment with balanced block design. AB - SUBJECTS: Random sample of 50 general practitioners (42 agreed to participate) from 165 in a geographically defined area of Oxfordshire. AB - INTERVENTIONS: Doctors prescribed for 36 simulated cases constructed from real consultations. Levels of computer support were control (alphabetical list of drugs), limited support (list of preferred drugs), and full support (the same list with explanations available for suggestions). AB - MAIN OUTCOME MEASURES: Percentage of cases where doctors ignored a cheaper, equally effective drug; prescribing score (a measure of how closely prescriptions matched expert recommendations); interview to elicit doctors' views of support system. AB - RESULTS: Computer support significantly improved the quality of prescribing. Doctors ignored a cheaper, equally effective drug in a median 50% (range 25%-75%) of control cases, compared with 36% (8%-67%) with limited support and 35% (0-67%) with full support (P < 0.001). The median prescribing score rose from 6.0 units (4.2-7.0) with control support to 6.8 (5.8 to 7.7) and 6.7 (5.6 to 7.8) with limited and full support (P < 0.001). Of 41 doctors, 36 (88%) found the system easy to use and 24 (59%) said they would be likely to use it in practice. AB - CONCLUSIONS: Computer support improved compliance with prescribing guidelines, reducing the occasions when doctors ignored a cheaper, equally effective drug. The system was easy to operate, and most participating doctors would be likely to use it in practice. IS - 0959-8138 IL - 0959-535X PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 9345174 [pubmed] ID - PMC2127529 [pmc] PP - ppublish LG - English DP - 1997 Sep 27 DC - 19971118 EZ - 1997/11/05 00:00 DA - 1997/11/05 00:01 DT - 1997/11/05 YR - 1997 ED - 19971118 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9345174 <651. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9330544 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hauser R AU - Westermann B AU - Probst R FA - Hauser, R FA - Westermann, B FA - Probst, R IN - Hauser, R. Department of Otorhinolaryngology, University of Basel, Kantonsspital, Switzerland. TI - A non-invasive patient registration and reference system for interactive intraoperative localization in intranasal sinus surgery. SO - Proceedings of the Institution of Mechanical Engineers. Part H - Journal of Engineering in Medicine. 211(4):327-34, 1997 AS - Proc Inst Mech Eng [H]. 211(4):327-34, 1997 NJ - Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine PI - Journal available in: Print PI - Citation processed from: Print JC - 8908934, abj IO - Proc Inst Mech Eng H SB - Index Medicus CP - England MH - Biopsy MH - Humans MH - Intraoperative Care MH - *Paranasal Sinus Diseases/dg [Diagnostic Imaging] MH - *Paranasal Sinus Diseases/su [Surgery] MH - Phantoms, Imaging MH - Posture MH - *Preoperative Care MH - *Radiographic Image Enhancement/mt [Methods] MH - Reoperation MH - Reproducibility of Results MH - Therapy, Computer-Assisted/is [Instrumentation] MH - *Therapy, Computer-Assisted/mt [Methods] MH - Tomography, X-Ray Computed AB - A basic problem common to all systems for computer assisted surgery (CAS) is patient referencing, or the transfer of preoperative image data to the intraoperative pathology. The authors describe a highly precise CAS system with non-invasive referencing that can be used in ear, nose and throat (ENT) surgery of the paranasal sinuses. It is based on optical digitizing with several custom-made self-localizing surgical instruments. The accuracy of the system was tested in an experimental model using a plastic head. Measurements of repositioning the reference bow had a mean error of 0.81 mm +/- 0.31 mm. The system was evaluated clinically with 11 patients who received surgery for different pathologies of the paranasal sinuses. These trials met with a high rate of success and specific results are reported. IS - 0954-4119 IL - 0954-4119 DO - https://dx.doi.org/10.1243/0954411971534458 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 9330544 [pubmed] ID - 10.1243/0954411971534458 [doi] PP - ppublish LG - English DP - 1997 DC - 19971031 EZ - 1997/01/01 00:00 DA - 1997/10/23 00:01 DT - 1997/01/01 00:00 YR - 1997 ED - 19971031 RD - 20170214 UP - 20170215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=9330544 <652. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9330544 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hauser R AU - Westermann B AU - Probst R FA - Hauser, R FA - Westermann, B FA - Probst, R IN - Hauser, R. Department of Otorhinolaryngology, University of Basel, Kantonsspital, Switzerland. TI - A non-invasive patient registration and reference system for interactive intraoperative localization in intranasal sinus surgery. SO - Proceedings of the Institution of Mechanical Engineers. Part H - Journal of Engineering in Medicine. 211(4):327-34, 1997 AS - Proc Inst Mech Eng [H]. 211(4):327-34, 1997 NJ - Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine PI - Journal available in: Print PI - Citation processed from: Print JC - 8908934, abj IO - Proc Inst Mech Eng H SB - Index Medicus CP - England MH - Biopsy MH - Humans MH - Intraoperative Care MH - *Paranasal Sinus Diseases/dg [Diagnostic Imaging] MH - *Paranasal Sinus Diseases/su [Surgery] MH - Phantoms, Imaging MH - Posture MH - *Preoperative Care MH - *Radiographic Image Enhancement/mt [Methods] MH - Reoperation MH - Reproducibility of Results MH - Therapy, Computer-Assisted/is [Instrumentation] MH - *Therapy, Computer-Assisted/mt [Methods] MH - Tomography, X-Ray Computed AB - A basic problem common to all systems for computer assisted surgery (CAS) is patient referencing, or the transfer of preoperative image data to the intraoperative pathology. The authors describe a highly precise CAS system with non-invasive referencing that can be used in ear, nose and throat (ENT) surgery of the paranasal sinuses. It is based on optical digitizing with several custom-made self-localizing surgical instruments. The accuracy of the system was tested in an experimental model using a plastic head. Measurements of repositioning the reference bow had a mean error of 0.81 mm +/- 0.31 mm. The system was evaluated clinically with 11 patients who received surgery for different pathologies of the paranasal sinuses. These trials met with a high rate of success and specific results are reported. IS - 0954-4119 IL - 0954-4119 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 9330544 [pubmed] PP - ppublish LG - English DP - 1997 DC - 19971031 EZ - 1997/01/01 00:00 DA - 1997/10/23 00:01 DT - 1997/01/01 00:00 YR - 1997 ED - 19971031 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9330544 <653. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9263002 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Maurer CR Jr AU - Fitzpatrick JM AU - Wang MY AU - Galloway RL Jr AU - Maciunas RJ AU - Allen GS FA - Maurer, C R Jr FA - Fitzpatrick, J M FA - Wang, M Y FA - Galloway, R L Jr FA - Maciunas, R J FA - Allen, G S IN - Maurer, C R Jr. Department of Computer Science and Neurological Surgery, Vanderbilt University, Nashville, TN 37235, USA. TI - Registration of head volume images using implantable fiducial markers. SO - IEEE Transactions on Medical Imaging. 16(4):447-62, 1997 Aug AS - IEEE Trans Med Imaging. 16(4):447-62, 1997 Aug NJ - IEEE transactions on medical imaging PI - Journal available in: Print PI - Citation processed from: Print JC - cox, 8310780 IO - IEEE Trans Med Imaging SB - Index Medicus CP - United States MH - Brain Diseases/di [Diagnosis] MH - Brain Diseases/su [Surgery] MH - Computer Simulation MH - Craniotomy MH - Head/dg [Diagnostic Imaging] MH - Head/pa [Pathology] MH - Head/su [Surgery] MH - *Head MH - Humans MH - Image Processing, Computer-Assisted MH - Magnetic Resonance Imaging/mt [Methods] MH - *Neurosurgery/is [Instrumentation] MH - Neurosurgery/mt [Methods] MH - Phantoms, Imaging MH - Prospective Studies MH - *Prostheses and Implants MH - *Stereotaxic Techniques/is [Instrumentation] MH - Tomography, Emission-Computed, Single-Photon/mt [Methods] MH - Tomography, X-Ray Computed/mt [Methods] AB - In this paper, we describe an extrinsic-point-based, interactive image-guided neurosurgical system designed at Vanderbilt University, Nashville, TN, as part of a collaborative effort among the Departments of Neurological Surgery, Computer Science, and Biomedical Engineering. Multimodal image-to-image (II) and image-to-physical (IP) registration is accomplished using implantable markers. Physical space tracking is accomplished with optical triangulation. We investigate the theoretical accuracy of point-based registration using numerical simulations, the experimental accuracy of our system using data obtained with a phantom, and the clinical accuracy of our system using data acquired in a prospective clinical trial by six neurosurgeons at four medical centers from 158 patients undergoing craniotomies to resect cerebral lesions. We can determine the position of our markers with an error of approximately 0.4 mm in X-ray computed tomography (CT) and magnetic resonance (MR) images and 0.3 mm in physical space. The theoretical registration error using four such markers distributed around the head in a configuration that is clinically practical is approximately 0.5-0.6 mm. The mean CT-physical registration error for the phantom experiments is 0.5 mm and for the clinical data obtained with rigid head fixation during scanning is 0.7 mm. The mean CT-MR registration error for the clinical data obtained without rigid head fixation during scanning is 1.4 mm, which is the highest mean error that we observed. These theoretical and experimental findings indicate that this system is an accurate navigational aid that can provide real-time feedback to the surgeon about anatomical structures encountered in the surgical field. IS - 0278-0062 IL - 0278-0062 DO - https://dx.doi.org/10.1109/42.611354 PT - Clinical Trial PT - Journal Article PT - Multicenter Study ID - 9263002 [pubmed] ID - 10.1109/42.611354 [doi] PP - ppublish LG - English DP - 1997 Aug DC - 19971007 EZ - 1997/08/01 00:00 DA - 2001/03/28 10:01 DT - 1997/08/01 YR - 1997 ED - 19971007 RD - 20161124 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9263002 <654. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9261583 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Cainzos M AU - Sayek I AU - Wacha H AU - Pulay I AU - Dominion L AU - Aeberhard PF AU - Hau T AU - Aasen AO FA - Cainzos, M FA - Sayek, I FA - Wacha, H FA - Pulay, I FA - Dominion, L FA - Aeberhard, P F FA - Hau, T FA - Aasen, A O IN - Cainzos, M. Department of Surgery, University of Santiago de Compostela, Hospital General de Galicia, Spain. TI - Septic complications after biliary tract stone surgery: a review and report of the European prospective study. SO - Hepato-Gastroenterology. 44(16):959-67, 1997 Jul-Aug AS - Hepatogastroenterology. 44(16):959-67, 1997 Jul-Aug NJ - Hepato-gastroenterology PI - Journal available in: Print PI - Citation processed from: Print JC - 8007849, ga7 IO - Hepatogastroenterology SB - Index Medicus CP - Greece MH - Adult MH - Aged MH - Aged, 80 and over MH - Anti-Bacterial Agents/tu [Therapeutic Use] MH - Antibiotic Prophylaxis/mt [Methods] MH - Bacteria/ip [Isolation & Purification] MH - Biliary Tract/mi [Microbiology] MH - *Biliary Tract Surgical Procedures/ae [Adverse Effects] MH - *Cholelithiasis/su [Surgery] MH - Europe MH - Female MH - Follow-Up Studies MH - Humans MH - Incidence MH - Male MH - Middle Aged MH - *Postoperative Complications/ep [Epidemiology] MH - Postoperative Complications/et [Etiology] MH - Postoperative Complications/pc [Prevention & Control] MH - Prospective Studies MH - *Sepsis/ep [Epidemiology] MH - Sepsis/et [Etiology] MH - Sepsis/pc [Prevention & Control] AB - We report a prospective, controlled study of the incidence of septic complications following biliary tract stone surgery. This study included a total of 280 patients operated on in eight hospitals in various European countries. In this study the computer program "Surgery" was used. Of 280 patients, 77 (27.5%) were male and 203 (72.5%) were female. The age ranged from 20 to 92 years (mean 54.8 years); 78.9% of the cases corresponded to clean-contaminated surgery; 85% of the patients received antibiotic prophylaxis with cefazolin. Twenty-one patients developed postoperative septic complications (7.5%) of which 12 (4.3%) were wound infections; five patients (1.8%) had intra-abdominal infections. The wound infection rate was 3.2% in clean-contaminated surgery, 7.7% in contaminated and 20% in dirty (p < 0.02). In laparoscopic cholecystectomy the global rate of septic complications was 3.6% vs. 12.6% in open cholecystectomy (p < 0.01); 2.4% and 6.3% wound infection respectively. The mean age of patients who developed postoperative septic complications was 61.5 years and 54.2 years old who did not develop any complications (p < 0.03). The duration of the postoperative period was 5 days in patients without infection and 13 days in patients with infection (p < 0.0001). Two patients died, one of them (0.4%) caused by sepsis. In addition to the European prospective study, a review of the problems of sepsis in biliary surgery was carried out. RN - 0 (Anti-Bacterial Agents) IS - 0172-6390 IL - 0172-6390 PT - Clinical Trial PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article PT - Multicenter Study ID - 9261583 [pubmed] PP - ppublish LG - English DP - 1997 Jul-Aug DC - 19970929 EZ - 1997/07/01 00:00 DA - 1997/07/01 00:01 DT - 1997/07/01 YR - 1997 ED - 19970929 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9261583 <655. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 9186315 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Zelefsky MJ AU - Whitmore WF Jr FA - Zelefsky, M J FA - Whitmore, W F Jr IN - Zelefsky, M J. Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA. TI - Long-term results of retropubic permanent 125iodine implantation of the prostate for clinically localized prostatic cancer. SO - Journal of Urology. 158(1):23-9; discussion 29-30, 1997 Jul AS - J Urol. 158(1):23-9; discussion 29-30, 1997 Jul NJ - The Journal of urology PI - Journal available in: Print PI - Citation processed from: Print JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Actuarial Analysis MH - Adenocarcinoma/bl [Blood] MH - Adenocarcinoma/mo [Mortality] MH - *Adenocarcinoma/rt [Radiotherapy] MH - Adenocarcinoma/sc [Secondary] MH - Adult MH - Aged MH - Brachytherapy/ae [Adverse Effects] MH - Brachytherapy/mt [Methods] MH - *Brachytherapy MH - Disease-Free Survival MH - Follow-Up Studies MH - Humans MH - *Iodine Radioisotopes/tu [Therapeutic Use] MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Neoplasm Staging MH - Prostate-Specific Antigen/bl [Blood] MH - Prostatic Neoplasms/bl [Blood] MH - Prostatic Neoplasms/mo [Mortality] MH - Prostatic Neoplasms/pa [Pathology] MH - *Prostatic Neoplasms/rt [Radiotherapy] MH - Regression Analysis MH - Survival Rate MH - Time Factors AB - PURPOSE: The historical series of retropubic prostate radioactive source implantation from the Memorial Sloan-Kettering Cancer Center has served as the framework for the current transperineal implant approaches used in the treatment of localized prostatic cancer. We report the final assessment of the 15-year outcome. AB - MATERIALS AND METHODS: Between March 1970 and December 1987, 1,078 patients with biopsy proved adenocarcinoma of the prostate were treated at our cancer center with permanent implantation of 125iodine via a retropubic approach. In addition, all patients underwent bilateral pelvic lymphadenectomy before implantation. The clinical stages of disease were B1 in 234 patients (22%), B2 in 472 (44%), B3 in 145 (14%) and C in 227 (20%). Of the patients 733 (68%) had pathologically negative lymph nodes, whereas 345 (32%) had positive lymph nodes at lymph node dissection. Median followup was 11 years. AB - RESULTS: Multivariate analysis identified nodal involvement, high grade disease, clinical stage B3/C and implant doses less than 140 Gy, as independent predictors of local relapse. Independent predictors of distant metastases included nodal involvement, stage B3/C disease and poorly differentiated histological status. The local recurrence-free survival rates for patients with negative nodes at 5, 10 and 15 years were 69, 44 and 24%, respectively. The distant metastases-free survival rates at 5, 10 and 15 years for patients with negative lymph nodes were 59, 36 and 21%, respectively. AB - CONCLUSIONS: 125Iodine implantation of the prostate via the retropubic approach was associated with a greater than expected incidence of local relapse at 15 years. Technical limitations of the retropubic technique resulting in suboptimal distribution of the isotope within the prostate are believed to be the explanation for the inferior local control outcome. Although long-term results are not yet available, the 5-year results of the computer optimized transperineal prostate implantation suggest that improved implant techniques will translate into a greater likelihood of tumor control. RN - 0 (Iodine Radioisotopes) RN - EC 3-4-21-77 (Prostate-Specific Antigen) IS - 0022-5347 IL - 0022-5347 PT - Clinical Trial PT - Journal Article ID - 9186315 [pubmed] PP - ppublish LG - English DP - 1997 Jul DC - 19970714 EZ - 1997/07/01 00:00 DA - 2001/03/28 10:01 DT - 1997/07/01 YR - 1997 ED - 19970714 RD - 20041117 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=9186315 <656. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 8947701 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Jones R AU - Pearson J AU - Cawsey A AU - Barrett A FA - Jones, R FA - Pearson, J FA - Cawsey, A FA - Barrett, A IN - Jones, R. Dept. Public Health, University of Glasgow, Scotland. TI - Information for patients with cancer. Does personalization make a difference? Pilot study results and randomised trial in progress. SO - Proceedings/AMIA Annual Fall Symposium. :423-7, 1996 AS - Proc AMIA Annu Fall Symp. :423-7, 1996 NJ - Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium PI - Journal available in: Print PI - Citation processed from: Print JC - cqw, 9617342 IO - Proc AMIA Annu Fall Symp PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233206 SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Humans MH - *Medical Records Systems, Computerized MH - Middle Aged MH - *Neoplasms MH - Online Systems MH - *Patient Education as Topic/mt [Methods] MH - *Patient Participation MH - Pilot Projects AB - Although there are a number of groups working on the provision of personalized patient information there has been little evaluation. We have developed and piloted a method of giving patients on-line access to their own medical records with associated explanations. We are comparing, in a randomised trial, personalized with general computer based information for patients undergoing radiotherapy for cancer. We present results from the pilot study and the evaluation methods to be employed. IS - 1091-8280 IL - 1091-8280 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 8947701 [pubmed] ID - PMC2233206 [pmc] PP - ppublish LG - English DP - 1996 DC - 19970128 EZ - 1996/01/01 00:00 DA - 1996/01/01 00:01 DT - 1996/01/01 YR - 1996 ED - 19970128 RD - 20161021 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=8947701 <657. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 8911520 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Karakiewicz PI AU - Aprikian AG AU - Meshref AW AU - Bazinet M FA - Karakiewicz, P I FA - Aprikian, A G FA - Meshref, A W FA - Bazinet, M IN - Karakiewicz, P I. UROMED Prostate Cancer Detection Center, Montreal, Quebec, Canada. TI - Computer-assisted comparative analysis of four-sector and six-sector biopsies of the prostate. SO - Urology. 48(5):747-50, 1996 Nov AS - Urology. 48(5):747-50, 1996 Nov NJ - Urology PI - Journal available in: Print PI - Citation processed from: Print JC - wsy, 0366151 IO - Urology SB - Index Medicus CP - United States MH - Aged MH - *Biopsy/mt [Methods] MH - *Diagnosis, Computer-Assisted MH - Humans MH - Male MH - Prospective Studies MH - *Prostatic Neoplasms/pa [Pathology] MH - Random Allocation AB - OBJECTIVES: To assess the potential difference in positive biopsy rates between four-sector and six-sector biopsy methods. AB - METHODS: This computer-assisted analysis is based on the records of 156 consecutive patients previously diagnosed with T1c cancer on systematic sextant biopsy of the peripheral zone. For each patient the computer randomly deleted one biopsy result from the left and right prostatic lobes. The deletion process was repeated 1000 times. Based on four randomly chosen biopsy cores, we determined the number of undetected cancers initially diagnosed with sextant biopsy. AB - RESULTS: Based on four-sector biopsy cores of the peripheral zone, between 6 and 30 (3.8% to 19.2% of cases) nonpalpable, isoechoic prostate cancers that were detected with sextant biopsy would have remained undiagnosed. AB - CONCLUSIONS: Our results suggest that the number of biopsy cores used in the early detection of nonpalpable, isoechoic prostate cancer may substantially affect the rate of positive findings. IS - 0090-4295 IL - 0090-4295 DI - S0090-4295(96)00230-0 DO - https://dx.doi.org/10.1016/S0090-4295(96)00230-0 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 8911520 [pubmed] ID - S0090-4295(96)00230-0 [pii] ID - 10.1016/S0090-4295(96)00230-0 [doi] PP - ppublish LG - English DP - 1996 Nov DC - 19961216 EZ - 1996/11/01 00:00 DA - 1996/11/01 00:01 DT - 1996/11/01 YR - 1996 ED - 19961216 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=8911520 <658. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 8813919 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hubert J AU - Cormier L AU - Gerbaud PF AU - Guillemin F AU - Pertek JP AU - Mangin P FA - Hubert, J FA - Cormier, L FA - Gerbaud, P F FA - Guillemin, F FA - Pertek, J P FA - Mangin, P IN - Hubert, J. Department of Urology, Centre Hospitalier Universitaire Brabois, Nancy, France. TI - Computer-controlled monitoring of bladder pressure in the prevention of 'TUR syndrome': a randomized study of 53 cases. SO - British Journal of Urology. 78(2):228-33, 1996 Aug AS - Br J Urol. 78(2):228-33, 1996 Aug NJ - British journal of urology PI - Journal available in: Print PI - Citation processed from: Print JC - b3k, 15740090r IO - Br J Urol SB - Index Medicus CP - England MH - Adenoma/pp [Physiopathology] MH - Adenoma/su [Surgery] MH - Aged MH - Aged, 80 and over MH - Carcinoma/pp [Physiopathology] MH - Carcinoma/su [Surgery] MH - Endoscopy MH - Humans MH - Male MH - Manometry MH - Middle Aged MH - Monitoring, Intraoperative MH - Organ Size MH - Pressure MH - *Prostatectomy/mt [Methods] MH - Prostatic Neoplasms/pp [Physiopathology] MH - Prostatic Neoplasms/su [Surgery] MH - Sensitivity and Specificity MH - Syndrome MH - Therapy, Computer-Assisted MH - Urinary Bladder Diseases/et [Etiology] MH - Urinary Bladder Diseases/pp [Physiopathology] MH - *Urinary Bladder Diseases/pc [Prevention & Control] MH - Urinary Catheterization MH - *Urology/is [Instrumentation] AB - OBJECTIVE: To evaluate the performance of a computer-controlled monitor of bladder pressure in the prevention of transurethral resection (TUR) syndrome. AB - PATIENTS AND METHODS: The in vitro pressure loss in catheters and endoscopes of different size was measured for irrigant flow rates of 0-500 mL/min to calibrate them before surgery. The calibrations were used in a computerized monitoring system designed to control bladder pressure during TUR of the prostate (TURP). The performance of the system was assessed in a randomized study of 53 patients with a prostate adenoma or carcinoma (Group A, 27 unmonitored patients; Group B, 26 monitored patients). The primary criterion for evaluating the absorption of irrigating fluid was the level of glycine in the blood. AB - RESULTS: When patients with capsule perforation were included in the analysis, there was no statistically significant difference in mean glycine absorption between the groups, although glycine levels were highest in Group A, particularly in those cases with perforation (four in Group A; two in Group B). When the results for patients with capsule perforation were excluded from the analysis, there was a significant difference in the incidence of irrigant absorption between the groups. The extent of absorption was not related to the duration of operation (which was shorter in Group B) nor to the weight of resection chippings. AB - CONCLUSION: The continuous computerized monitoring of bladder pressure during TURP effectively reduced the absorption of irrigant fluid, making the procedure safer for the patient and easier for the surgeon. IS - 0007-1331 IL - 0007-1331 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial ID - 8813919 [pubmed] PP - ppublish LG - English DP - 1996 Aug DC - 19961024 EZ - 1996/08/01 00:00 DA - 1996/08/01 00:01 DT - 1996/08/01 YR - 1996 ED - 19961024 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=8813919 <659. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 8700582 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Spencer EH FA - Spencer, E H TI - The ROBODOC clinical trial: a robotic assistant for total hip arthroplasty. SO - Orthopaedic Nursing. 15(1):9-14, 1996 Jan-Feb AS - Orthop Nurs. 15(1):9-14, 1996 Jan-Feb NJ - Orthopedic nursing PI - Journal available in: Print PI - Citation processed from: Print JC - orn, 8409486 IO - Orthop Nurs SB - Nursing Journal CP - United States MH - Controlled Clinical Trials as Topic MH - Hip Prosthesis/ae [Adverse Effects] MH - *Hip Prosthesis/mt [Methods] MH - Hip Prosthesis/nu [Nursing] MH - Humans MH - Multicenter Studies as Topic MH - *Robotics/mt [Methods] MH - Software AB - Operating room teams at three U.S. hospitals are participating in a controlled clinical trial to evaluate the use of a surgical robot in total hip arthroplasty. The robot, called the ROBODOC Surgical Assistant System, precisely prepares the femoral canal for the placement of a "press fit" cementless prosthesis. The Food and Drug Administration (FDA) requires that the robot, as an investigational device, be tested in a controlled clinical trial to demonstrate safety and efficacy. The clinical trial will include 300 patients who must meet specific criteria before enrollment and randomization. This article describes the need for new surgical technology, ROBODOC's development history, hardware and software components of the system, the patient population and surgical protocol for the clinical trial, special nursing care requirements, and considerations for patient rehabilitation. IS - 0744-6020 IL - 0744-6020 PT - Journal Article ID - 8700582 [pubmed] PP - ppublish LG - English DP - 1996 Jan-Feb DC - 19960905 EZ - 1996/01/01 00:00 DA - 1996/01/01 00:01 DT - 1996/01/01 YR - 1996 ED - 19960905 RD - 20141009 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=8700582 <660. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 8522708 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Onaka H AU - Hirota Y AU - Shimada S AU - Kita Y AU - Sakai Y AU - Kawakami Y AU - Suzuki S AU - Kawamura K FA - Onaka, H FA - Hirota, Y FA - Shimada, S FA - Kita, Y FA - Sakai, Y FA - Kawakami, Y FA - Suzuki, S FA - Kawamura, K IN - Onaka, H. Department of Internal Medicine, Osaka Medical College, Takatsuki, Japan. TI - Clinical observation of spontaneous anginal attacks and multivessel spasm in variant angina pectoris with normal coronary arteries: evaluation by 24-hour 12-lead electrocardiography with computer analysis. SO - Journal of the American College of Cardiology. 27(1):38-44, 1996 Jan AS - J Am Coll Cardiol. 27(1):38-44, 1996 Jan NJ - Journal of the American College of Cardiology PI - Journal available in: Print PI - Citation processed from: Print JC - h50, 8301365 IO - J. Am. Coll. Cardiol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Analysis of Variance MH - *Angina Pectoris, Variant/di [Diagnosis] MH - Angina Pectoris, Variant/pp [Physiopathology] MH - Arrhythmias, Cardiac/dt [Drug Therapy] MH - Arrhythmias, Cardiac/pp [Physiopathology] MH - Cardiac Catheterization MH - Coronary Angiography MH - Coronary Vasospasm/pp [Physiopathology] MH - Electrocardiography, Ambulatory/mt [Methods] MH - *Electrocardiography, Ambulatory MH - Ergonovine MH - Female MH - Humans MH - Isosorbide Dinitrate/tu [Therapeutic Use] MH - Male MH - Middle Aged MH - Norepinephrine/tu [Therapeutic Use] MH - Oxytocics MH - Prognosis MH - Risk Factors MH - Signal Processing, Computer-Assisted MH - Vasoconstrictor Agents/tu [Therapeutic Use] MH - Vasodilator Agents/tu [Therapeutic Use] AB - OBJECTIVES: Using a new, computerized 24-h 12-lead electrocardiographic (ECG) recording and analysis system (the EAGLE system), we sought to evaluate the clinical manifestations of ischemic episodes in patients with variant angina and normal coronary arteries. AB - BACKGROUND: Although the prognosis of variant angina without significant organic stenosis is generally good, the incidence of multivessel spasm, a major prognostic factor, is surprisingly high in provocation tests. AB - METHODS: A total of 122 patients with suspected variant or unstable angina underwent 24-h examination with the EAGLE system and two-channel Holter monitoring. Thirty patients in this group were diagnosed as having variant angina with normal or nearly normal coronary arteries. Twenty-two (73%) of these 30 patients developed anginal attacks with ST segment elevation during monitoring and were enrolled in the study. AB - RESULTS: The 22 patients had a total of 138 episodes of transient ST segment elevation and 13 episodes of ST segment depression. No arrhythmias were observed during ST segment depression, but 26 episodes of ST segment elevation (19%) were associated with arrhythmias: 7 with premature ventricular contractions, 3 with ventricular bigeminy, 3 with complete atrioventricular (AV) block, 1 with complete AV block and couplets of premature ventricular contractions and 12 with marked sinus bradycardia (< 45 beats/min). Ten (45%) of the 22 patients had multivessel spasm. We observed three different patterns of multivessel spasm: 1) spasm at a different site on different occasions (migratory spasm); 2) spasm that sequentially affected two different sites; 3) simultaneous spasm at more than one site. The duration of ST segment elevation was much longer in patients with sequential and simultaneous spasm than in those with single-vessel spasm, and arrhythmias were more frequent during these two types of multivessel spasm. AB - CONCLUSIONS: Although the prognosis of multivessel spasm is believed to be poor, this may not necessarily be so. Anginal attacks due to sequential and simultaneous multivessel spasm seem to be more dangerous than those involving single-vessel spasm or migratory multivessel spasm. RN - 0 (Oxytocics) RN - 0 (Vasoconstrictor Agents) RN - 0 (Vasodilator Agents) RN - IA7306519N (Isosorbide Dinitrate) RN - WH41D8433D (Ergonovine) RN - X4W3ENH1CV (Norepinephrine) IS - 0735-1097 IL - 0735-1097 DI - 0735-1097(95)00423-8 DO - https://dx.doi.org/10.1016/0735-1097(95)00423-8 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 8522708 [pubmed] ID - 0735-1097(95)00423-8 [pii] ID - 10.1016/0735-1097(95)00423-8 [doi] PP - ppublish LG - English DP - 1996 Jan DC - 19960125 EZ - 1996/01/01 00:00 DA - 1996/01/01 00:01 DT - 1996/01/01 YR - 1996 ED - 19960125 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=8522708 <661. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 8522707 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Komaru T AU - Isoyama S AU - Sekiguchi N AU - Akai K AU - Shiba N AU - Yasuda S AU - Funakoshi M AU - Shirato K AU - Zuguchi M AU - Nozaki E AU - Nishioka O AU - Tamaki K FA - Komaru, T FA - Isoyama, S FA - Sekiguchi, N FA - Akai, K FA - Shiba, N FA - Yasuda, S FA - Funakoshi, M FA - Shirato, K FA - Zuguchi, M FA - Nozaki, E FA - Nishioka, O FA - Tamaki, K IN - Komaru, T. First Department of Internal Medicine, Tohoku University School of Medicine, Sendai, Japan. TI - Coronary angioplasty ameliorates hypoperfusion-induced endothelial dysfunction in patients with stable angina pectoris. SO - Journal of the American College of Cardiology. 27(1):30-7, 1996 Jan AS - J Am Coll Cardiol. 27(1):30-7, 1996 Jan NJ - Journal of the American College of Cardiology PI - Journal available in: Print PI - Citation processed from: Print JC - h50, 8301365 IO - J. Am. Coll. Cardiol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Angina Pectoris/dg [Diagnostic Imaging] MH - *Angina Pectoris/pp [Physiopathology] MH - *Angina Pectoris/th [Therapy] MH - *Angioplasty, Balloon, Coronary MH - Coronary Angiography MH - Coronary Vessels/de [Drug Effects] MH - Dose-Response Relationship, Drug MH - *Endothelium, Vascular/pp [Physiopathology] MH - Follow-Up Studies MH - Humans MH - Injections, Intra-Arterial MH - Male MH - Middle Aged MH - Nitroglycerin/ad [Administration & Dosage] MH - Observer Variation MH - Prospective Studies MH - Regression Analysis MH - Risk Factors MH - Stroke Volume/ph [Physiology] MH - Substance P/ad [Administration & Dosage] MH - Vasodilator Agents/ad [Administration & Dosage] AB - OBJECTIVES: This study sought to investigate the effect of coronary angioplasty on chronic hypoperfusion-induced endothelial dysfunction in patients with coronary heart disease. AB - BACKGROUND: The endothelium is an important component for organ flow regulation. Ischemia with or without reperfusion is known to cause endothelial dysfunction. We tested the hypothesis that chronic hypoperfusion impairs endothelial function in the angiographically normal coronary artery segment distal to stenosis and that the impairment by chronic hypoperfusion is reduced by coronary angioplasty. AB - METHODS: In 13 patients with stable angina pectoris, substance P (10, 30 and 100 pmol) and nitroglycerin (200 micrograms) were sequentially infused into the coronary artery in a cumulative manner on the day after coronary angioplasty. In 10 of these patients, vascular responses to these agents were again investigated 3 months after angioplasty. Changes in vascular diameter were evaluated in vessels located proximal and distal to the target lesion, both of which were angiographically normal, by performing computer-assisted quantitative coronary angiography. In five patients, the transstenotic pressure gradient was also measured with a pressure sensor-mounted guide wire before angioplasty. AB - RESULTS: On the day after angioplasty, the magnitude of dilation by substance P in distal segments was significantly less than that in proximal segments and inversely correlated with the transstenotic pressure gradient (p < 0.05) and lesion stenosis (p < 0.05). There was no difference in nitroglycerin-induced vasodilation between the two vessel segment groups. Three months later, the impaired response to substance P in the distal segment was restored to normal. AB - CONCLUSIONS: We conclude that chronic hypoperfusion impairs endothelium-dependent dilation of coronary artery distal to critical stenosis in patients with ischemic heart disease and that coronary angioplasty ameliorates the endothelial dysfunction within 3 months. RN - 0 (Vasodilator Agents) RN - 33507-63-0 (Substance P) RN - G59M7S0WS3 (Nitroglycerin) IS - 0735-1097 IL - 0735-1097 DI - 0735-1097(95)00441-6 DO - https://dx.doi.org/10.1016/0735-1097(95)00441-6 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 8522707 [pubmed] ID - 0735-1097(95)00441-6 [pii] ID - 10.1016/0735-1097(95)00441-6 [doi] PP - ppublish LG - English DP - 1996 Jan DC - 19960125 EZ - 1996/01/01 00:00 DA - 1996/01/01 00:01 DT - 1996/01/01 YR - 1996 ED - 19960125 RD - 20161123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=8522707 <662. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 7500476 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Kavoussi LR AU - Moore RG AU - Adams JB AU - Partin AW FA - Kavoussi, L R FA - Moore, R G FA - Adams, J B FA - Partin, A W IN - Kavoussi, L R. Brady Urological Institute, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, USA. TI - Comparison of robotic versus human laparoscopic camera control .[Erratum appears in J Urol 1997 Oct;158(4):1530] SO - Journal of Urology. 154(6):2134-6, 1995 Dec AS - J Urol. 154(6):2134-6, 1995 Dec NJ - The Journal of urology PI - Journal available in: Print PI - Citation processed from: Print JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Female MH - Humans MH - *Laparoscopes MH - *Laparoscopy/mt [Methods] MH - Male MH - *Prostatic Hyperplasia/su [Surgery] MH - *Robotics MH - *Urologic Diseases/su [Surgery] AB - PURPOSE: We investigated the accuracy and use of a robotic surgical arm compared to a human surgical assistant during urological laparoscopic surgery. AB - MATERIALS AND METHODS: A total of 11 patients undergoing pelvic laparoscopic procedures that required identical bilateral surgical manipulations was evaluated. On 1 side a robotic surgical arm was used to manipulate the laparoscopic camera, while on the contralateral side the camera was positioned by a human surgical assistant. The side (left versus right) on which the robot was used was alternated with each case. Parameters assessed included operative time, erroneous camera motions, complications and outcome. AB - RESULTS: All procedures were successfully completed without complications. Laparoscopic camera positioning was significantly steadier with less inadvertent movements when under robotic control (p < 0.0005). Operative times during dissections using the robot or human assistant were not statistically different. AB - CONCLUSIONS: A robotic device can more effectively manipulate and accurately control the video endoscope than a human assistant during laparoscopic procedures. IS - 0022-5347 IL - 0022-5347 DI - S0022-5347(01)66715-6 PT - Clinical Trial PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article ID - 7500476 [pubmed] ID - S0022-5347(01)66715-6 [pii] PP - ppublish LG - English DP - 1995 Dec DC - 19960118 EZ - 1995/12/01 00:00 DA - 1995/12/01 00:01 DT - 1995/12/01 YR - 1995 ED - 19960118 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=7500476 <663. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 7486179 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Fiset P AU - Mathers L AU - Engstrom R AU - Fitzgerald D AU - Brand SC AU - Hsu F AU - Shafer SL FA - Fiset, P FA - Mathers, L FA - Engstrom, R FA - Fitzgerald, D FA - Brand, S C FA - Hsu, F FA - Shafer, S L IN - Fiset, P. Department of Anaesthesia, McGill University, Montreal, Canada. TI - Pharmacokinetics of computer-controlled alfentanil administration in children undergoing cardiac surgery. SO - Anesthesiology. 83(5):944-55, 1995 Nov AS - Anesthesiology. 83(5):944-55, 1995 Nov NJ - Anesthesiology PI - Journal available in: Print PI - Citation processed from: Print JC - 4sg, 1300217 IO - Anesthesiology SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Alfentanil/ad [Administration & Dosage] MH - Alfentanil/bl [Blood] MH - *Alfentanil/pk [Pharmacokinetics] MH - Anesthetics, Intravenous/ad [Administration & Dosage] MH - Anesthetics, Intravenous/bl [Blood] MH - *Anesthetics, Intravenous/pk [Pharmacokinetics] MH - *Cardiac Surgical Procedures MH - *Cardiopulmonary Bypass MH - Child MH - Child, Preschool MH - Drug Therapy, Computer-Assisted MH - Half-Life MH - Humans MH - Infant MH - Infusion Pumps MH - Intraoperative Period MH - Models, Biological MH - Nonlinear Dynamics MH - Postoperative Period MH - Regression Analysis AB - BACKGROUND: Cardiopulmonary bypass (CPB) induces changes in the pharmacokinetics of drugs. The purpose of this study was to model the pharmacokinetics of alfentanil in children undergoing cardiac surgery to provide accurate dosage titration intraoperatively as well as in the postoperative period. AB - METHODS: Fourteen children (aged 3 months to 8 yr) undergoing cardiac surgery with CPB were administered alfentanil via a computer-controlled infusion pump. During surgery, the computer-controlled infusion pump was set to target plasma alfentanil concentrations of 500-2500 micrograms/ml. After surgery, the computer-controlled infusion pump was set to target plasma concentrations of 200-500 micrograms/ml. Parameters for children previously published by Goresky et al. were programmed into the device. Arterial blood samples were taken throughout the infusion. Plasma samples were assayed by radioimmunoassay. Alfentanil pharmacokinetics were estimated using a pooled-data approach with a simple weight-proportional, three-compartment mamillary model with parameters expressed in volumes and clearances as well as a CPB-adjusted, three-compartment model in which the parameters were allowed to change before, during, and after CPB. The accuracy of the three models was compared using cross-validation. AB - RESULTS: Plasma alfentanil concentrations during computer-controlled infusion pump administration exceeded target concentrations for the first 10 min of drug administration, and from 300 min to the end of the study. The median absolute performance error was 33%. Pharmacokinetic modeling estimated a set of parameters for a simple three-compartment model with a median absolute weighted residual of 18.4%. A CPB-adjusted model nominally decreased the median absolute weighted residual to 17.0%. The performance of these models as measured by cross-validation performance was 18.9% median absolute performance error for the simple model and 18.4% median absolute performance error for the CPB-adjusted model. Parameters for the simple three-compartment model are: V1 = 19.2 ml.kg-1; V2 = 99 ml.kg-1; V3 = 2344 ml.kg-1; Cl1 = 2.5 ml.kg-1.min-1; Cl2 = 38 ml.kg-1.min-1; and Cl3 = 15 ml.kg-1.min-1. In the CPB-adjusted model V1, V2, and Cl2 changed with the onset of CPB. After CPB, V1 and Cl2 returned to the initial values, while V2 was described by a third value. AB - CONCLUSIONS: The population pharmacokinetics of alfentanil in children undergoing cardiac surgery were well described by both a simple weight-proportional, three-compartment model and a weight-proportional, CPB-adjusted three-compartment model. Cross-validation estimated an expected median inaccuracy of approximately 18-20% with the estimated models in identical experimental circumstances. The flexible CPB-adjusted pharmacokinetic model could be used for modeling any drug with linear pharmacokinetics given in the context of CPB. RN - 0 (Anesthetics, Intravenous) RN - 1N74HM2BS7 (Alfentanil) IS - 0003-3022 IL - 0003-3022 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, Non-P.H.S. ID - 7486179 [pubmed] PP - ppublish LG - English DP - 1995 Nov DC - 19951221 EZ - 1995/11/01 00:00 DA - 1995/11/01 00:01 DT - 1995/11/01 YR - 1995 ED - 19951221 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=7486179 <664. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 7586344 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Ozaki Y AU - Keane D AU - Serruys PW FA - Ozaki, Y FA - Keane, D FA - Serruys, P W IN - Ozaki, Y. Department of Interventional Cardiology, Erasmus University, Rotterdam, The Netherlands. TI - Progression and regression of coronary stenosis in the long-term follow-up of vasospastic angina. SO - Circulation. 92(9):2446-56, 1995 Nov 01 AS - Circulation. 92(9):2446-56, 1995 Nov 01 NJ - Circulation PI - Journal available in: Print PI - Citation processed from: Print JC - daw, 0147763 IO - Circulation SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Angina Pectoris, Variant/co [Complications] MH - Angina Pectoris, Variant/dg [Diagnostic Imaging] MH - *Angina Pectoris, Variant/pp [Physiopathology] MH - Coronary Angiography MH - Coronary Artery Disease/dg [Diagnostic Imaging] MH - Coronary Artery Disease/et [Etiology] MH - *Coronary Artery Disease/pp [Physiopathology] MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Risk Factors MH - Vasoconstriction AB - BACKGROUND: Whether focal vasospasticity plays a pathogenic role in the progression or regression of coronary atherosclerosis is unknown. To determine whether evidence for such a role exists, we studied long-term changes in coronary luminal measurements in patients with vasospastic angina. AB - METHODS AND RESULTS: Quantitative coronary angiography and repeated ergonovine provocation tests were performed 45 +/- 16 months apart in 30 patients. All patients had vasospastic anginal symptoms and coronary spasm on the initial provocation test. On the 30 patients, 16 had persistent symptoms of vasospastic angina and showed coronary spasm at the same site on the follow-up angiogram (group 1), while the remaining 14 whose vasospastic anginal symptoms disappeared at follow-up demonstrated a negative response to ergonovine on the follow-up tests (group 2). There was no significant difference in patients' baseline characteristics between the two groups. Long-term changes in minimal (MLD) and mean (MEAN) luminal diameter were measured (in millimeters) after administration of isosorbide dinitrate in 19 spastic and 93 nonspastic segments in group 1 and in 17 previously spastic and 81 nonspastic segments in group 2. Both MLD and MEAN were measured in 210 coronary segments of the 30 patients at baseline and after administration of ergonovine and isosorbide dinitrate by use of a computer-based quantitative coronary angiography system. Stenosis progression and regression of individual lesions were defined as a change in MLD of > or = 0.40 mm. In group 1, both the MLD and MEAN of 19 spastic segments were significantly smaller (progression) at follow-up compared with the initial angiogram (MLD, 2.21 +/- 0.54 initially versus 1.95 +/- 0.65 at follow-up, P < .01; MEAN, 2.80 +/- 0.56 initially versus 2.56 +/- 0.58 at follow-up, P < .01), whereas the MLD and MEAN of 93 nonspastic segments in group 1 were not significantly different between the initial and follow-up angiograms (MLD, 2.47 +/- 0.67 initially versus 2.44 +/- 0.69 at follow-up, P = NS; MEAN, 2.96 +/- 0.69 initially versus 2.91 +/- 0.68 at follow-up, P = NS). In group 2, the MLD of the 17 previously spastic segments significantly improved (regression) at follow-up (MLD, 1.99 +/- 0.68 initially versus 2.24 +/- 0.54 at follow-up, P < .05); the MLD and MEAN of the 81 nonspastic segments were not significantly different (MLD, 2.36 +/- 0.59 initially versus 2.39 +/- 0.60 at follow-up, P = NS; MEAN, 2.81 +/- 0.58 initially versus 2.81 +/- 0.61 at follow-up, P = NS). In group 1, significant stenosis progression of individual lesions was observed more frequently at spastic than nonspastic segments (6 of 19 versus 10 of 93, P < .05), whereas stenosis regression was observed in no spastic and 3 nonspastic segments (P = NS). In group 2, stenosis progression was observed at 1 previously spastic segment and 4 nonspastic segments (P = NS), while significant stenosis regression of individual lesions was seen more commonly in previously spastic than nonspastic segments (6 of 17 versus 7 of 81, P < .01). AB - CONCLUSIONS: These results have demonstrated in patients an association between persistent vasospastic activity and progression of atherosclerosis and an association between cessation of vasospastic activity and regression of atherosclerosis. IS - 0009-7322 IL - 0009-7322 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 7586344 [pubmed] PP - ppublish LG - English DP - 1995 Nov 01 DC - 19951220 EZ - 1995/11/01 00:00 DA - 1995/11/01 00:01 DT - 1995/11/01 YR - 1995 ED - 19951220 RD - 20161123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=7586344 <665. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 7658546 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Giesen RJ AU - Huynen AL AU - Aarnink RG AU - de la Rosette JJ AU - vd Kaa C AU - Oosterhof GO AU - Debruyne FM AU - Wijkstra H FA - Giesen, R J FA - Huynen, A L FA - Aarnink, R G FA - de la Rosette, J J FA - vd Kaa, C FA - Oosterhof, G O FA - Debruyne, F M FA - Wijkstra, H IN - Giesen, R J. Department of Urology, University Hospital Nijmegen, The Netherlands. TI - Computer analysis of transrectal ultrasound images of the prostate for the detection of carcinoma: a prospective study in radical prostatectomy specimens. SO - Journal of Urology. 154(4):1397-400, 1995 Oct AS - J Urol. 154(4):1397-400, 1995 Oct NJ - The Journal of urology PI - Journal available in: Print PI - Citation processed from: Print JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - *Diagnosis, Computer-Assisted MH - False Negative Reactions MH - False Positive Reactions MH - Humans MH - Male MH - Middle Aged MH - Observer Variation MH - Prospective Studies MH - Prostatectomy MH - *Prostatic Neoplasms/dg [Diagnostic Imaging] MH - Prostatic Neoplasms/pa [Pathology] MH - Prostatic Neoplasms/su [Surgery] MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Ultrasonography AB - PURPOSE: The reliability and objectivity of computer assisted transrectal ultrasound are examined. AB - MATERIALS AND METHODS: Pathological examination of radical prostatectomy specimens was compared prospectively to automated cancer detection in corresponding transrectal ultrasound images. AB - RESULTS: For automated cancer detection, a sensitivity of 0.75 and a specificity of 0.78 were obtained. Moreover, 74% of human interpretation of the percentage of malignancy in the analyzed images was equal to the actual calculated percentage (Pearson's product moment correlation coefficient 0.85). AB - CONCLUSIONS: Comparing these results to those obtained with normal transrectal ultrasound, automated analysis provides additional information in the interpretation of transrectal ultrasound images by color coding them in an objective manner according to the probability of malignancy. IS - 0022-5347 IL - 0022-5347 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 7658546 [pubmed] PP - ppublish LG - English DP - 1995 Oct DC - 19951002 EZ - 1995/10/01 00:00 DA - 1995/10/01 00:01 DT - 1995/10/01 YR - 1995 ED - 19951002 RD - 20161123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=7658546 <666. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 7748089 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Wolberg WH AU - Street WN AU - Heisey DM AU - Mangasarian OL FA - Wolberg, W H FA - Street, W N FA - Heisey, D M FA - Mangasarian, O L IN - Wolberg, W H. Department of Surgery, University of Wisconsin, Madison, USA. TI - Computerized breast cancer diagnosis and prognosis from fine-needle aspirates. SO - Archives of Surgery. 130(5):511-6, 1995 May AS - Arch Surg. 130(5):511-6, 1995 May NJ - Archives of surgery (Chicago, Ill. : 1960) PI - Journal available in: Print PI - Citation processed from: Print JC - 8ia, 9716528 IO - Arch Surg SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - *Biopsy, Needle MH - *Breast Neoplasms/pa [Pathology] MH - Cell Nucleus/pa [Pathology] MH - *Diagnosis, Computer-Assisted MH - Humans MH - Neoplasm Recurrence, Local MH - Predictive Value of Tests MH - Prognosis AB - OBJECTIVE: To use digital image analysis and machine learning to (1) improve breast mass diagnosis based on fine-needle aspirates and (2) improve breast cancer prognostic estimations. AB - DESIGN: An interactive computer system evaluates, diagnoses, and determines prognosis based on cytologic features derived from a digital scan of fine-needle aspirate slides. AB - SETTING: The University of Wisconsin (Madison) Departments of Computer Science and Surgery and the University of Wisconsin Hospital and Clinics. AB - PATIENTS: Five hundred sixty-nine consecutive patients (212 with cancer and 357 with benign masses) provided the data for the diagnostic algorithm, and an additional 118 (31 with malignant masses and 87 with benign masses) consecutive, new patients tested the algorithm. One hundred ninety of these patients with invasive cancer and without distant metastases were used for prognosis. AB - INTERVENTIONS: Surgical biopsy specimens were taken from all cancers and some benign masses. The remaining cytologically benign masses were followed up for a year and surgical biopsy specimens were taken if they changed in size or character. Patients with cancer received standard treatment. AB - OUTCOME MEASURES: Cross validation was used to project the accuracy of the diagnostic algorithm and to determine the importance of prognostic features. In addition, the mean errors were calculated between the actual times of distant disease occurrence and the times predicted using various prognostic features. Statistical analyses were also done. AB - RESULTS: The predicted diagnostic accuracy was 97% and the actual diagnostic accuracy on 118 new samples was 100%. Tumor size and lymph node status were weak prognosticators compared with nuclear features, in particular those measuring nuclear size. Compared with the actual time for recurrence, the mean error of predicted times for recurrence with the nuclear features was 17.9 months and was 20.1 months with tumor size and lymph node status (P = .11). AB - CONCLUSION: Computer technology will improve breast fine-needle aspirate accuracy and prognostic estimations. IS - 0004-0010 IL - 0004-0010 PT - Clinical Trial PT - Journal Article PT - Research Support, U.S. Gov't, Non-P.H.S. ID - 7748089 [pubmed] PP - ppublish LG - English DP - 1995 May DC - 19950613 EZ - 1995/05/01 00:00 DA - 1995/05/01 00:01 DT - 1995/05/01 YR - 1995 ED - 19950613 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=7748089 <667. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 7722345 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Syvanne M AU - Nieminen MS AU - Frick MH FA - Syvanne, M FA - Nieminen, M S FA - Frick, M H IN - Syvanne, M. First Department of Medicine, Helsinki University Central Hospital. TI - Accuracy and precision of quantitative arteriography in the evaluation of coronary artery disease after coronary bypass surgery. A validation study. CM - Comment in: Int J Card Imaging. 1994 Dec;10(4):241-2; PMID: 7722344 SO - International Journal of Cardiac Imaging. 10(4):243-52, 1994 Dec AS - Int J Card Imaging. 10(4):243-52, 1994 Dec NJ - International journal of cardiac imaging PI - Journal available in: Print PI - Citation processed from: Print JC - ijd, 8600426 IO - Int J Card Imaging SB - Index Medicus CP - Netherlands MH - Cholesterol, HDL MH - Confidence Intervals MH - *Coronary Angiography/sn [Statistics & Numerical Data] MH - *Coronary Artery Bypass MH - Coronary Disease/bl [Blood] MH - *Coronary Disease/dg [Diagnostic Imaging] MH - Coronary Disease/su [Surgery] MH - Double-Blind Method MH - Follow-Up Studies MH - Gemfibrozil/ad [Administration & Dosage] MH - Graft Occlusion, Vascular/bl [Blood] MH - Graft Occlusion, Vascular/dg [Diagnostic Imaging] MH - Graft Occlusion, Vascular/dt [Drug Therapy] MH - Humans MH - Male MH - Observer Variation MH - Postoperative Complications/bl [Blood] MH - *Postoperative Complications/dg [Diagnostic Imaging] MH - Postoperative Complications/dt [Drug Therapy] MH - *Radiographic Image Interpretation, Computer-Assisted MH - Reproducibility of Results MH - Veins/tr [Transplantation] AB - Computer-assisted quantitative coronary arteriography (QCA) has gained widespread acceptance in assessing changes in coronary dimensions over time, but little is known about the utility of QCA in patients having undergone coronary bypass surgery. As a validation study, we analyzed the accuracy and precision of QCA in a subset of the baseline angiograms of a clinical trial in 395 post-bypass men with low HDL cholesterol concentrations who have been randomized to receive double-blind gemfibrozil or placebo for 2 1/2 years. Based on repeat measurements of the same cineframe, the average diameter of a segment (ADS) had a mean coefficient of variation (CV) of 3.1%. The mean CVs of the minimum luminal diameter (MLD), percent diameter stenosis (PDS) and stenotic flow reserve of an obstruction were 8.6, 10.2 and 9.8%, respectively, but the area of the atherosclerotic plaque had an unacceptably high CV, 24.0%. When the measurements from two contrast injections into a native coronary artery during the same angiographic session were compared, precision (standard deviation of the differences) was 0.198 mm for ADS, 0.192 mm for MLD, and 7.37% for PDS. Variability was not substantially reduced when measurements from 3 or 5 consecutive cineframes were averaged. Comparable repeatability was found when venous bypass grafts were imaged twice, whether the grafts themselves or the grafted native vessels were analyzed. We conclude that QCA has an acceptable accuracy and precision in analyzing coronary dimensions in bypass-grafted patients. A change of 0.40 mm in ADS and MLD, and 20% in PDS represent true progression or regression of coronary atherosclerosis with more than 95% confidence. RN - 0 (Cholesterol, HDL) RN - Q8X02027X3 (Gemfibrozil) IS - 0167-9899 IL - 0167-9899 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 7722345 [pubmed] PP - ppublish LG - English DP - 1994 Dec DC - 19950519 EZ - 1994/12/01 00:00 DA - 1994/12/01 00:01 DT - 1994/12/01 YR - 1994 ED - 19950519 RD - 20161123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=7722345 <668. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 7900230 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Date H AU - Andou A AU - Shimizu N FA - Date, H FA - Andou, A FA - Shimizu, N IN - Date, H. Department of Surgery II, Okayama University School of Medicine, Japan. TI - The value of limited resection for "clinical" stage I peripheral non-small cell lung cancer in poor-risk patients: comparison of limited resection and lobectomy by a computer-assisted matched study. SO - Tumori. 80(6):422-6, 1994 Dec 31 AS - Tumori. 80(6):422-6, 1994 Dec 31 NJ - Tumori PI - Journal available in: Print PI - Citation processed from: Print JC - wjs, 0111356 IO - Tumori SB - Index Medicus CP - Italy MH - Aged MH - Carcinoma, Non-Small-Cell Lung/pa [Pathology] MH - Carcinoma, Non-Small-Cell Lung/pp [Physiopathology] MH - *Carcinoma, Non-Small-Cell Lung/su [Surgery] MH - Female MH - Humans MH - Lung Neoplasms/pa [Pathology] MH - Lung Neoplasms/pp [Physiopathology] MH - *Lung Neoplasms/su [Surgery] MH - Male MH - Matched-Pair Analysis MH - Middle Aged MH - Neoplasm Staging MH - *Pneumonectomy/mt [Methods] MH - Respiratory Function Tests MH - Retrospective Studies MH - Survival Rate MH - Treatment Outcome AB - AIM: A computer-assisted retrospective matched study was devised to compare limited resection and lobectomy for non-small cell lung cancer. AB - METHODS: Of 353 patients undergoing operation for "clinical" stage I peripheral non-small cell lung cancer, 16 patients undergoing limited resection (because of poor risk) could be matched satisfactorily with 16 patients undergoing lobectomy (as a standard procedure) on the basis of age, sex, histology, tumor location, and tumor size with computer assistance. AB - RESULTS: No hospital death was observed in the 32 patients. Three of the 16 limited resection patients (19%) developed local recurrence in the same lobe. The 5-year survival rate was 55.5% for limited resection and 73.7% for lobectomy (P = not significant). For tumors more than 2.0 cm in diameter, 3-year survival rate was significantly lower in the limited resection group than in the lobectomy group: 34.3% versus 85.7%, P < 0.05. For adenocarcinoma, limited resection seemed to be more unfavorable than lobectomy: 5-year survival rate, 34.3% versus 75.0%, P = 0.07. AB - CONCLUSIONS: Limited resection offered a good survival rate without hospital death for poor-risk patients; however, lobectomy should be performed for good-risk patients. IS - 0300-8916 IL - 0300-8916 PT - Clinical Trial PT - Controlled Clinical Trial PT - Journal Article ID - 7900230 [pubmed] PP - ppublish LG - English DP - 1994 Dec 31 DC - 19950427 EZ - 1994/12/31 00:00 DA - 1994/12/31 00:01 DT - 1994/12/31 YR - 1994 ED - 19950427 RD - 20081212 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=7900230 <669. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 7858783 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Attfield SF AU - Warren-Forward M AU - Wilton T AU - Sambatakakis A FA - Attfield, S F FA - Warren-Forward, M FA - Wilton, T FA - Sambatakakis, A IN - Attfield, S F. Orthotic & Disability Research Centre, Derbyshire Royal Infirmary, Derby, UK. TI - Measurement of soft tissue imbalance in total knee arthroplasty using electronic instrumentation. SO - Medical Engineering & Physics. 16(6):501-5, 1994 Nov AS - Med Eng Phys. 16(6):501-5, 1994 Nov NJ - Medical engineering & physics PI - Journal available in: Print PI - Citation processed from: Print JC - bzu, 9422753 IO - Med Eng Phys SB - Index Medicus CP - England MH - Anthropometry/is [Instrumentation] MH - *Arthritis/pa [Pathology] MH - Arthritis/su [Surgery] MH - *Connective Tissue/pa [Pathology] MH - Electronics/is [Instrumentation] MH - Humans MH - *Joint Deformities, Acquired/pa [Pathology] MH - Joint Deformities, Acquired/su [Surgery] MH - *Knee Joint/pa [Pathology] MH - *Knee Prosthesis MH - Monitoring, Intraoperative MH - Reproducibility of Results MH - Weight-Bearing AB - The existence of soft tissue contractures in arthritis and the presence of soft tissue imbalance at the time of a total knee arthroplasty causing deformity in the coronal plane has been debated extensively. This discussion was based on the use of instrumentation which tensed the medial and lateral soft tissues in an uncontrolled manner during the operation. Previous work by this research team has developed a surgical instrument to quantify soft tissue imbalance independently of the compressive passive loads through the knee. In order to validate this assumption, an electronic measuring system was developed to record the soft tissue imbalance at 0.25 mm distraction intervals of the knee. This soft-tissue measuring system consists of a surgical instrument containing electronic transducers, an analogue conditioning unit and a portable computer. The surgical instrument introduces a pivot to the centre of the knee in the coronal plane so that the clockwise and counterclockwise moments produced by the collateral soft tissues produce an angular deviation at the equilibrium position. Measurements of angular deviation and separation gap are recorded by the electronic transducers. Eight patients were measured whilst undergoing total knee replacement at Bretby Hall Orthopaedic Hospital. The mean change in angular deviation over an average distraction of the knee of 7.15 mm was 0.4 degrees with a standard deviation of 0.4. It is concluded that this is an acceptable error band for surgical measurement, and soft tissue imbalance can be defined as angular deviation independently of the passive compressive loads through the knee. IS - 1350-4533 IL - 1350-4533 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 7858783 [pubmed] PP - ppublish LG - English DP - 1994 Nov DC - 19950323 EZ - 1994/11/01 00:00 DA - 1994/11/01 00:01 DT - 1994/11/01 YR - 1994 ED - 19950323 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=7858783 <670. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 7802299 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Houltz E AU - Ricksten SE AU - Milocco I AU - Gustavsson T AU - Caidahl K FA - Houltz, E FA - Ricksten, S E FA - Milocco, I FA - Gustavsson, T FA - Caidahl, K IN - Houltz, E. Department of Anesthesia and Intensive Care, Sahlgrenska University Hospital, Gothenburg, Sweden. TI - Effects of adenosine infusion on systolic and diastolic left ventricular function after coronary artery bypass surgery: evaluation by computer-assisted quantitative 2-D and Doppler echocardiography. SO - Anesthesia & Analgesia. 80(1):47-53, 1995 Jan AS - Anesth Analg. 80(1):47-53, 1995 Jan NJ - Anesthesia and analgesia PI - Journal available in: Print PI - Citation processed from: Print JC - 4r8, 1310650 IO - Anesth. Analg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adenosine/ad [Administration & Dosage] MH - Adenosine/ae [Adverse Effects] MH - *Adenosine/pd [Pharmacology] MH - *Coronary Artery Bypass MH - Diastole MH - *Echocardiography, Doppler/mt [Methods] MH - Electrocardiography MH - Hemodynamics/de [Drug Effects] MH - Humans MH - Systole MH - *Ventricular Function, Left/de [Drug Effects] AB - The effects of adenosine on central hemodynamics, ST-segment changes, and left ventricular (LV) systolic and diastolic function, determined by transesophageal 2-D and Doppler echocardiography, were investigated in 20 patients shortly after coronary surgery. After control measurements, adenosine was infused at incremental infusion rates (30, 60, and 120 micrograms.kg-1.min-1). Adenosine caused dose-dependent increases in heart rate (68.0 +/- 11.2-74.0 +/- 15.7 bpm), cardiac output (3.23 +/- 0.76-4.17 +/- 0.67 L/min), and stroke volume (48.8 +/- 12.5-56.7 L/min), and stroke volume (48.8 +/- 12.5-56.7 mL), decreases in arterial pressure (84.8 +/- 16.6-63.3 +/- 15.2 mm Hg), and systemic and pulmonary vascular resistances (1994 +/- 510-1106 +/- 309 and 209 +/- 54-116 +/- 58 dyne.s.cm-5, respectively), but no changes in cardiac filling pressures. The mean ST segment was slightly but significantly depressed by adenosine (from 0.003 to 0.019 mV). Analysis of LV wall motion showed that adenosine caused no changes in the global area ejection fraction (GAEF), the segmental area ejection fraction (SAEF), or in the SAEF/GAEF ratio, indicating that no regional wall motion abnormalities appeared. Maximum early and late diastolic flow rates (Emax, Amax), determined by mitral Doppler analysis, increased (from 30.1 +/- 14.8 to 40.1 +/- 24.1 and from 37.8 +/- 15.7 to 46.4 +/- 31.3 cm/s, respectively), as did the deceleration slope of the early diastolic filling (from -151 +/- 67 to -210 +/- 107 cm/s-2), whereas no changes were found in the ratio between Emax and Amax, the deceleration time of early diastolic filling, or the velocity time integrals of early or late diastolic filling.(ABSTRACT TRUNCATED AT 250 WORDS) RN - K72T3FS567 (Adenosine) IS - 0003-2999 IL - 0003-2999 PT - Clinical Trial PT - Controlled Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 7802299 [pubmed] PP - ppublish LG - English DP - 1995 Jan DC - 19950124 EZ - 1995/01/01 00:00 DA - 1995/01/01 00:01 DT - 1995/01/01 YR - 1995 ED - 19950124 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=7802299 <671. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 7961001 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Mageras GS AU - Fuks Z AU - O'Brien J AU - Brewster LJ AU - Burman C AU - Chui CS AU - Leibel SA AU - Ling CC AU - Masterson ME AU - Mohan R AU - et al FA - Mageras, G S FA - Fuks, Z FA - O'Brien, J FA - Brewster, L J FA - Burman, C FA - Chui, C S FA - Leibel, S A FA - Ling, C C FA - Masterson, M E FA - Mohan, R IN - Mageras, G S. Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, NY 10021. TI - Initial clinical experience with computer-controlled conformal radiotherapy of the prostate using a 50-MeV medical microtron. SO - International Journal of Radiation Oncology, Biology, Physics. 30(4):971-8, 1994 Nov 15 AS - Int J Radiat Oncol Biol Phys. 30(4):971-8, 1994 Nov 15 NJ - International journal of radiation oncology, biology, physics PI - Journal available in: Print PI - Citation processed from: Print JC - g97, 7603616 IO - Int. J. Radiat. Oncol. Biol. Phys. SB - Index Medicus CP - United States MH - Humans MH - Male MH - *Prostatic Neoplasms/rt [Radiotherapy] MH - Radiotherapy Dosage MH - Radiotherapy, Computer-Assisted/is [Instrumentation] MH - *Radiotherapy, Computer-Assisted/mt [Methods] MH - Reproducibility of Results MH - Software AB - PURPOSE: We have described previously a model for delivering computer-controlled radiation treatments. We report here on the implementation and first year's clinical experience with such treatments using a 50 MeV medical microtron. AB - METHODS AND MATERIALS: The microtron is equipped with a multileaf collimator and is capable of setting up and treating a sequence of fixed fields called segments, under computer control. An external computer derives machine parameters for the segments from a three-dimensional treatment planning system, transfers them to the microtron control computer, checks the machine settings before allowing dose delivery to begin, and records the treatment. We describe the patient treatment methodology, portal film acquisition, electronic portal imaging, and quality assurance. AB - RESULTS: Patient treatments began in July 1992, comprising six-segment conformal treatments of the prostate. Using the recorded treatment data, the system performance has been examined and compared to other treatment machines. The average treatment time is 10 min, of which 4 min is for computer-controlled setup and irradiation; the remaining time is for patient positioning and checking of clearances. Long-term reproducibility of computer-controlled setup of the gantry and multileaf position is better than 0.5 degrees and 1 mm, respectively. Termination due to a machine fault has occurred in 5.5% of treatments, improving to 2.5% in recent months. AB - CONCLUSION: Our initial experience indicates that computer-controlled segmental therapy can be performed reliably on a routine basis. Treatment times with the microtron are significantly shorter than with conventional linacs, and setup accuracy is consistent with that needed for conformal therapy. We believe that treatment times can be further improved through software upgrades and integration of electronic portal imaging. IS - 0360-3016 IL - 0360-3016 DI - 0360-3016(94)90374-3 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. ID - 7961001 [pubmed] ID - 0360-3016(94)90374-3 [pii] PP - ppublish GI - No: P01-CA-59017 Organization: (CA) *NCI NIH HHS* Country: United States LG - English DP - 1994 Nov 15 DC - 19941215 EZ - 1994/11/15 00:00 DA - 1994/11/15 00:01 DT - 1994/11/15 YR - 1994 ED - 19941215 RD - 20071114 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=7961001 <672. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 7973431 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Eskelinen M AU - Ikonen J AU - Lipponen P FA - Eskelinen, M FA - Ikonen, J FA - Lipponen, P IN - Eskelinen, M. Dept. of Surgery, University of Kuopio, Finland. TI - Contributions of history-taking, physical examination, and computer assistance to diagnosis of acute small-bowel obstruction. A prospective study of 1333 patients with acute abdominal pain. SO - Scandinavian Journal of Gastroenterology. 29(8):715-21, 1994 Aug AS - Scand J Gastroenterol. 29(8):715-21, 1994 Aug NJ - Scandinavian journal of gastroenterology PI - Journal available in: Print PI - Citation processed from: Print JC - ucs, 0060105 IO - Scand. J. Gastroenterol. SB - Index Medicus CP - England MH - *Abdomen, Acute/et [Etiology] MH - Adult MH - Cohort Studies MH - Diagnosis, Computer-Assisted MH - Female MH - Humans MH - Intestinal Obstruction/co [Complications] MH - *Intestinal Obstruction/di [Diagnosis] MH - Intestinal Obstruction/ep [Epidemiology] MH - Logistic Models MH - Male MH - Medical History Taking MH - Physical Examination MH - Predictive Value of Tests MH - Prospective Studies MH - Risk Factors MH - Sensitivity and Specificity AB - BACKGROUND: The accuracy of clinical diagnosis of acute small-bowel studied in connection with the survey of acute abdominal pain by the Research Committee of the World Organization of Gastroenterology (OMGE). Criteria for inclusion and the diagnostic criteria of this prospective study were those set out by the OMGE Research Committee. AB - METHODS: The clinical findings in each patient were recorded in detail on a pre-defined structured data collection sheet, and the collected data were compared with the final diagnosis of patients. AB - RESULTS: The most efficient symptoms in the diagnosis of acute small-bowel obstruction were previous abdominal surgery (relative risk (RR) = 12.1) and type of pain (colic/intermittent versus steady) (RR = 2.4). The most efficient clinical tests were abdominal distension (yes versus no) (RR = 13.1) and bowel sounds (abnormal versus normal) (RR = 9.0). The sensitivity of the clinical decision was 0.75, with a specificity of 0.99 and an efficiency of 0.98. The computer-based diagnostic score reached a sensitivity of 0.87 with a specificity of 0.95 and an efficiency of 0.95. AB - CONCLUSIONS: Acute abdominal pain with distension, abnormal bowel sounds, and previous abdominal surgery are indicative of a small-bowel obstruction. A computer-based diagnostic score increases the sensitivity and usefulness index of the diagnosis of acute small-bowel obstruction in comparison with clinical decision alone. IS - 0036-5521 IL - 0036-5521 PT - Clinical Trial PT - Controlled Clinical Trial PT - Journal Article PT - Multicenter Study ID - 7973431 [pubmed] PP - ppublish LG - English DP - 1994 Aug DC - 19941212 EZ - 1994/08/01 00:00 DA - 1994/08/01 00:01 DT - 1994/08/01 YR - 1994 ED - 19941212 RD - 20041117 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=7973431 <673. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 8026027 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hodis HN AU - Mack WJ AU - Azen SP AU - Alaupovic P AU - Pogoda JM AU - LaBree L AU - Hemphill LC AU - Kramsch DM AU - Blankenhorn DH FA - Hodis, H N FA - Mack, W J FA - Azen, S P FA - Alaupovic, P FA - Pogoda, J M FA - LaBree, L FA - Hemphill, L C FA - Kramsch, D M FA - Blankenhorn, D H IN - Hodis, H N. Atherosclerosis Research Institute, University of Southern California School of Medicine, Los Angeles 90033. TI - Triglyceride- and cholesterol-rich lipoproteins have a differential effect on mild/moderate and severe lesion progression as assessed by quantitative coronary angiography in a controlled trial of lovastatin. SO - Circulation. 90(1):42-9, 1994 Jul AS - Circulation. 90(1):42-9, 1994 Jul NJ - Circulation PI - Journal available in: Print PI - Citation processed from: Print JC - daw, 0147763 IO - Circulation SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Adult MH - Aged MH - *Cholesterol/bl [Blood] MH - *Coronary Angiography MH - Coronary Artery Disease/bl [Blood] MH - *Coronary Artery Disease/dg [Diagnostic Imaging] MH - *Coronary Artery Disease/dt [Drug Therapy] MH - Double-Blind Method MH - Female MH - Humans MH - *Lipoproteins/bl [Blood] MH - *Lovastatin/tu [Therapeutic Use] MH - Male MH - Middle Aged MH - Regression Analysis MH - Risk Factors MH - *Triglycerides/bl [Blood] AB - BACKGROUND: The Monitored Atherosclerosis Regression Study, a randomized, double-blind, placebo-controlled, 2-year trial of lovastatin monotherapy, found that coronary lesions < 50% diameter stenosis (%S) and coronary lesions > or = 50% S at baseline had different responses to therapy. We now report on clinical, lipid, and nonlipid risk factors of treatment response in these lesion subsets. AB - METHODS AND RESULTS: Two hundred seventy subjects, 37 to 67 years old, with plasma total cholesterol (TC) 190 to 295 mg/dL (4.91 to 7.63 mmol/L) and total triglyceride < 500 mg/dL (5.65 mmol/L) were randomized to low-fat, low-cholesterol diet and either lovastatin 80 mg/d or placebo. Logistic regression was used to model the association between risk factors and coronary lesion progression in mild/moderate (< 50% S) and severe (> or = 50% S) lesions in 220 angiogram pairs analyzed by computer quantitative coronary angiography. In the placebo group, risk factors (P < .05) for the progression of mild/moderate lesions were triglycerides and TC/high-density lipoprotein cholesterol (HDL-C). Risk factors for the progression of severe lesions were HDL-C (negative), low-density lipoprotein cholesterol (LDL-C)/HDL-C, and TC/HDL-C. TC/HDL-C was the predominant risk factor for both mild/moderate and severe lesions in the multivariate analysis. In the lovastatin group, with aggressive lowering of LDL-C and TC below 85 mg/dL and 156 mg/dL, respectively, risk factors for mild/moderate lesions included triglycerides and very-low-density lipoprotein-LDL-associated apolipoprotein C-III (apo C-III-heparin precipitate), a marker of triglyceride-rich lipoprotein particles. Apo C-III-heparin precipitate was the predominant risk factor in the multivariate analysis. Risk factors for severe lesions were LDL-C, LDL-C/HDL-C, TC/HDL-C, and apo B; LDL-C/HDL-C was the predominant risk factor. AB - CONCLUSIONS: These results indicate that triglyceride-rich lipoproteins and cholesterol-rich lipoproteins have a differential effect on mild/moderate and severe lesion progression, respectively. These results add to the growing evidence of the importance of triglyceride-rich lipoproteins as a risk factor for coronary artery disease and the need for treatment in the progression of atherosclerosis. RN - 0 (Lipoproteins) RN - 0 (Triglycerides) RN - 97C5T2UQ7J (Cholesterol) RN - 9LHU78OQFD (Lovastatin) IS - 0009-7322 IL - 0009-7322 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. ID - 8026027 [pubmed] PP - ppublish GI - No: NHLBI HL-45005 Organization: (HL) *NHLBI NIH HHS* Country: United States No: NHLBI-RO-1-HL-49885 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English DP - 1994 Jul DC - 19940811 EZ - 1994/07/01 00:00 DA - 1994/07/01 00:01 DT - 1994/07/01 YR - 1994 ED - 19940811 RD - 20161123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=8026027 <674. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 8181124 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Folland ED AU - Vogel RA AU - Hartigan P AU - Bates ER AU - Beauman GJ AU - Fortin T AU - Boucher C AU - Parisi AF FA - Folland, E D FA - Vogel, R A FA - Hartigan, P FA - Bates, E R FA - Beauman, G J FA - Fortin, T FA - Boucher, C FA - Parisi, A F IN - Folland, E D. Research Service, Veterans Affairs Medical Centers, West Roxbury, Mass. TI - Relation between coronary artery stenosis assessed by visual, caliper, and computer methods and exercise capacity in patients with single-vessel coronary artery disease. The Veterans Affairs ACME Investigators. CM - Comment in: Circulation. 1995 Jan 15;91(2):562; PMID: 7805265 SO - Circulation. 89(5):2005-14, 1994 May AS - Circulation. 89(5):2005-14, 1994 May NJ - Circulation PI - Journal available in: Print PI - Citation processed from: Print JC - daw, 0147763 IO - Circulation SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Angioplasty, Balloon, Coronary MH - Constriction, Pathologic/di [Diagnosis] MH - Coronary Angiography MH - *Coronary Disease/di [Diagnosis] MH - Coronary Disease/pp [Physiopathology] MH - Coronary Disease/th [Therapy] MH - *Coronary Vessels/pa [Pathology] MH - Exercise Test MH - *Exercise Tolerance/ph [Physiology] MH - Heart/dg [Diagnostic Imaging] MH - Humans MH - Image Processing, Computer-Assisted MH - Middle Aged MH - Radionuclide Imaging MH - Thallium Radioisotopes AB - BACKGROUND: Practitioners often assume a close relation between angiographic coronary artery stenosis and patient functional capacity. To test this unproven hypothesis, we analyzed the relation between coronary artery stenosis measured by different methods and maximal treadmill exercise tolerance in patients with single-vessel disease before and after intervention by percutaneous transluminal coronary angioplasty (PTCA). AB - METHODS AND RESULTS: Coronary angiography and maximal exercise testing off anti-ischemic medication were performed before random assignment of 227 patients with single-vessel coronary artery disease to PTCA or drug therapy. Six months later, angiography and exercise testing were repeated with patients assigned to PTCA off anti-ischemic therapy so that the altered coronary stenosis was the only consistent variable. Patients assigned to drug therapy were exercised on drug therapy. Coronary stenosis was assessed visually by the local investigator and quantitatively by blinded caliper and computer methods in central laboratories. Variabilities of caliper and computer measurements were established in a subset read twice. Visually estimated stenosis > or = 90% at baseline was associated with shorter exercise duration (7.9 versus 9.2 minutes, P < .04). Similar segregation at baseline was not observed with caliper or computer methods. Regardless of the method of measurement used, correlation between changes of lesion severity and exercise duration from baseline to follow-up was poor. Patients were angiographically classified as "better," "unchanged," or "worse" if follow-up stenosis was below, within, or above 2 SD of mean technical variability from baseline (+/- 18.8%, caliper, +/- 14.6%, computer). Exercise duration for PTCA patients improved among those with better lesions (+2.4 minutes, n = 50, P = .001) but also among those with unchanged lesions (+1.9 minutes, n = 41, P < or = .001). Unchanged medically treated patients improved less (+0.5 minutes, n = 86, P = .04). Results were similar when patients were angiographically classified by minimum lumen diameter. AB - CONCLUSIONS: Handheld calipers and quantitative coronary angiography are equivalent techniques for making anatomic measurements. Neither method identified patients having reduced exercise capacity at baseline as well as visual estimation. The relation between changes of coronary stenosis and exercise duration is highly variable, at least in part because of the insensitivity of angiographic methods for detecting small but potentially important changes. Minimal anatomic improvement 6 months after PTCA does not preclude a good functional outcome. Contrary to common belief, angiographic stenosis does not correlate well with functional capacity, even in patients with single-vessel disease. RN - 0 (Thallium Radioisotopes) IS - 0009-7322 IL - 0009-7322 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, U.S. Gov't, Non-P.H.S. ID - 8181124 [pubmed] PP - ppublish LG - English DP - 1994 May DC - 19940614 EZ - 1994/05/01 00:00 DA - 1994/05/01 00:01 DT - 1994/05/01 YR - 1994 ED - 19940614 RD - 20161123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=8181124 <675. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 8169104 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Stanford W AU - Erkonen WE AU - Cassell MD AU - Moran BD AU - Easley G AU - Carris RL AU - Albanese MA FA - Stanford, W FA - Erkonen, W E FA - Cassell, M D FA - Moran, B D FA - Easley, G FA - Carris, R L FA - Albanese, M A IN - Stanford, W. Department of Radiology, University of Iowa College of Medicine, Iowa City 52242. TI - Evaluation of a computer-based program for teaching cardiac anatomy. SO - Investigative Radiology. 29(2):248-52, 1994 Feb AS - Invest Radiol. 29(2):248-52, 1994 Feb NJ - Investigative radiology PI - Journal available in: Print PI - Citation processed from: Print JC - gwk, 0045377 IO - Invest Radiol SB - Index Medicus CP - United States MH - *Anatomy/ed [Education] MH - Cineradiography MH - *Computer-Assisted Instruction MH - Dissection MH - *Education, Medical, Undergraduate MH - Evaluation Studies as Topic MH - *Heart/ah [Anatomy & Histology] MH - Heart/dg [Diagnostic Imaging] MH - Humans MH - Tomography, X-Ray Computed AB - RATIONALE AND OBJECTIVES: The authors determined to what extent a computer-based program could enhance or substitute for cadaver dissection in teaching cardiac anatomy to first-year medical students. AB - METHODS: First-year medical students (n = 175) were randomized into four groups. Group 1 (control) received no instruction, group 2 participated in cardiac dissection, group 3 viewed the computer application, and group 4 performed cardiac dissection and then viewed the computer application. Each group was tested with 10 ultrafast computed tomographic static images and 8 cardiac cadaver specimens. AB - RESULTS: The computer program plus dissection was superior to either the computer program alone or dissection alone; however, the results varied according to the subtest used to assess the outcomes. AB - CONCLUSIONS: Cardiac computer instruction after dissection resulted in dramatically improved image testing performance. However, computer instruction should not replace dissection for teaching cardiac anatomy. IS - 0020-9996 IL - 0020-9996 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 8169104 [pubmed] PP - ppublish LG - English DP - 1994 Feb DC - 19940601 EZ - 1994/02/01 00:00 DA - 1994/02/01 00:01 DT - 1994/02/01 YR - 1994 ED - 19940601 RD - 20161123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=8169104 <676. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 8124838 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Haskell WL AU - Alderman EL AU - Fair JM AU - Maron DJ AU - Mackey SF AU - Superko HR AU - Williams PT AU - Johnstone IM AU - Champagne MA AU - Krauss RM AU - et al FA - Haskell, W L FA - Alderman, E L FA - Fair, J M FA - Maron, D J FA - Mackey, S F FA - Superko, H R FA - Williams, P T FA - Johnstone, I M FA - Champagne, M A FA - Krauss, R M IN - Haskell, W L. Division of Cardiovascular Medicine, Stanford University, Palo Alto, CA 94304-1583. TI - Effects of intensive multiple risk factor reduction on coronary atherosclerosis and clinical cardiac events in men and women with coronary artery disease. The Stanford Coronary Risk Intervention Project (SCRIP). SO - Circulation. 89(3):975-90, 1994 Mar AS - Circulation. 89(3):975-90, 1994 Mar NJ - Circulation PI - Journal available in: Print PI - Citation processed from: Print JC - daw, 0147763 IO - Circulation SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - California/ep [Epidemiology] MH - Coronary Angiography MH - Coronary Artery Disease/dg [Diagnostic Imaging] MH - Coronary Artery Disease/ep [Epidemiology] MH - *Coronary Artery Disease/pc [Prevention & Control] MH - Female MH - Follow-Up Studies MH - Hospitalization/sn [Statistics & Numerical Data] MH - Humans MH - Hypolipidemic Agents/tu [Therapeutic Use] MH - *Life Style MH - Lipids/bl [Blood] MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Time Factors AB - BACKGROUND: Recent clinical trials have shown that modification of plasma lipoprotein concentrations can favorably alter progression of coronary atherosclerosis, but no data exist on the effects of a comprehensive program of risk reduction involving both changes in lifestyle and medications. This study tested the hypothesis that intensive multiple risk factor reduction over 4 years would significantly reduce the rate of progression of atherosclerosis in the coronary arteries of men and women compared with subjects randomly assigned to the usual care of their physician. AB - METHODS AND RESULTS: Three hundred men (n = 259) and women (n = 41) (mean age, 56 +/- 7.4 years) with angiographically defined coronary atherosclerosis were randomly assigned to usual care (n = 155) or multifactor risk reduction (n = 145). Patients assigned to risk reduction were provided individualized programs involving a low-fat and -cholesterol diet, exercise, weight loss, smoking cessation, and medications to favorably alter lipoprotein profiles. Computer-assisted quantitative coronary arteriography was performed at baseline and after 4 years. The main angiographic outcome was the rate of change in the minimal diameter of diseased segments. All subjects underwent medical and risk factor evaluations at baseline and yearly for 4 years, and reasons for all hospitalizations and deaths were documented. Of the 300 subjects randomized, 274 (91.3%) completed a follow-up arteriogram, and 246 (82%) had comparative measurements of segments with visible disease at baseline and follow-up. Intensive risk reduction resulted in highly significant improvements in various risk factors, including low-density lipoprotein cholesterol and apolipoprotein B (both, 22%), high-density lipoprotein cholesterol (+12%), plasma triglycerides (-20%), body weight (-4%), exercise capacity (+20%), and intake of dietary fat (-24%) and cholesterol (-40%) compared with relatively small changes in the usual-care group. No change was observed in lipoprotein(a) in either group. The risk-reduction group showed a rate of narrowing of diseased coronary artery segments that was 47% less than that for subjects in the usual-care group (change in minimal diameter, -0.024 +/- 0.066 mm/y versus -0.045 +/- 0.073 mm/y; P < .02, two-tailed). Three deaths occurred in each group. There were 25 hospitalizations in the risk-reduction group initiated by clinical cardiac events compared with 44 in the usual-care group (rate ratio, 0.61; P = .05; 95% confidence interval, 0.4 to 0.9). AB - CONCLUSIONS: Intensive multifactor risk reduction conducted over 4 years favorably altered the rate of luminal narrowing in coronary arteries of men and women with coronary artery disease and decreased hospitalizations for clinical cardiac events. RN - 0 (Hypolipidemic Agents) RN - 0 (Lipids) IS - 0009-7322 IL - 0009-7322 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. ID - 8124838 [pubmed] PP - ppublish GI - No: HL-28292 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English DP - 1994 Mar DC - 19940413 EZ - 1994/03/01 00:00 DA - 1994/03/01 00:01 DT - 1994/03/01 YR - 1994 ED - 19940413 RD - 20161123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=8124838 <677. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 8261775 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lin DY FA - Lin, D Y IN - Lin, D Y. Department of Biostatistics, University of Washington, Seattle 98195. TI - MULCOX2: a general computer program for the Cox regression analysis of multivariate failure time data. SO - Computer Methods & Programs in Biomedicine. 40(4):279-93, 1993 Aug AS - Comput Methods Programs Biomed. 40(4):279-93, 1993 Aug NJ - Computer methods and programs in biomedicine PI - Journal available in: Print PI - Citation processed from: Print JC - doh, 8506513 IO - Comput Methods Programs Biomed SB - Index Medicus CP - Ireland MH - Age Factors MH - Cluster Analysis MH - Female MH - Granulomatous Disease, Chronic/th [Therapy] MH - Humans MH - Interferon-gamma/tu [Therapeutic Use] MH - Male MH - *Mathematical Computing MH - Multivariate Analysis MH - *Proportional Hazards Models MH - Schizophrenia/ge [Genetics] MH - *Software MH - Survival Analysis AB - Multivariate failure time data is commonly encountered in biomedicine, because each study subject may experience multiple events or because there exists clustering of subjects such that failure times within the same cluster are correlated. MULCOX2 implements a general statistical methodology for analyzing such data. This approach formulates the marginal distributions of multivariate failure times by Cox proportional hazards models without specifying the nature of dependence among related failure times. The baseline hazard functions for the marginal models may be identical or different. A variety of statistical inference can be made regarding the effects of (possibly time-dependent) covariates on the failure rates. Although designed primarily for the marginal approach, MULCOX2 is general enough to implement several alternative methods. The program runs on any computer with a FORTRAN compiler. The running time is minimal. Two illustrative examples are provided. RN - 82115-62-6 (Interferon-gamma) IS - 0169-2607 IL - 0169-2607 PT - Clinical Trial PT - Controlled Clinical Trial PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. ID - 8261775 [pubmed] PP - ppublish GI - No: R01 AI-291968 Organization: (AI) *NIAID NIH HHS* Country: United States No: R29 GM-47845 Organization: (GM) *NIGMS NIH HHS* Country: United States LG - English DP - 1993 Aug DC - 19940125 EZ - 1993/08/01 00:00 DA - 1993/08/01 00:01 DT - 1993/08/01 YR - 1993 ED - 19940125 RD - 20081121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=8261775 <678. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 8319169 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Saito S AU - Taguchi K AU - Nishimura N AU - Watanabe A AU - Ogoshi K AU - Niwa M AU - Furukawa T AU - Takahashi M FA - Saito, S FA - Taguchi, K FA - Nishimura, N FA - Watanabe, A FA - Ogoshi, K FA - Niwa, M FA - Furukawa, T FA - Takahashi, M IN - Saito, S. Third Department of Internal Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan. TI - Clinical usefulness of computer-assisted diagnosis using combination assay of tumor markers for pancreatic carcinoma. SO - Cancer. 72(2):381-8, 1993 Jul 15 AS - Cancer. 72(2):381-8, 1993 Jul 15 NJ - Cancer PI - Journal available in: Print PI - Citation processed from: Print JC - 0374236, clz IO - Cancer SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - *Adenocarcinoma/di [Diagnosis] MH - Adult MH - *Biomarkers, Tumor/an [Analysis] MH - *Diagnosis, Computer-Assisted MH - Diagnosis, Differential MH - Discriminant Analysis MH - Evaluation Studies as Topic MH - Humans MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Pancreatic Diseases/di [Diagnosis] MH - *Pancreatic Neoplasms/di [Diagnosis] MH - Retrospective Studies AB - BACKGROUND: There has been extensive use of serum tumor markers in diagnosing pancreatic adenocarcinoma. There is no tumor marker, however, that alone has sufficient diagnostic accuracy. It is necessary to know which combination of tumor markers should be used to detect pancreatic cancer, with respect to clinical usefulness and cost effectiveness. AB - METHODS: Serum levels of 17 kinds of tumor markers were determined in 145 patients and 40 healthy volunteers. Thirty-five patients with proven pancreatic adenocarcinoma, and 32 with benign pancreatobiliary disease (14 chronic pancreatitis and 18 biliary stones) were selected. For analysis of the usefulness of each tumor marker to differentiate these two groups, scatterplot and relative operating characteristic (ROC) analyses were used. A multivariate discriminant system to differentiate these two groups was developed using stepwise discriminant analysis by backward elimination selection. AB - RESULTS: The significance of each tumor marker varied according to the tumor volume. By ROC analysis, the markers were divided into four subgroups according to their usefulness in discriminating pancreatic adenocarcinoma from benign pancreatobiliary disease. A discriminant system consisting of two different discriminant functions using nine tumor markers (CA 19-9, DUPAN-2, TPA, elastase-1, lipase, amylase, gamma-glutamyl transpeptidase, alkaline phosphatase, and lactate dehydrogenase) was developed and designated CAMPAS-P; it could differentiate between all 35 cases of pancreatic adenocarcinoma and 32 cases of benign pancreatobiliary disease. On the other hand, CAMPAS-P showed a low positive rate in pancreatic tumors of unusual histologic type, and poor organ-specific diagnostic ability in various digestive organ malignancies. AB - CONCLUSIONS: CAMPAS-P may be very useful for differential diagnosis between pancreatic adenocarcinoma and benign pancreatobiliary disease. RN - 0 (Biomarkers, Tumor) IS - 0008-543X IL - 0008-543X PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 8319169 [pubmed] PP - ppublish LG - English DP - 1993 Jul 15 DC - 19930803 EZ - 1993/07/15 00:00 DA - 1993/07/15 00:01 DT - 1993/07/15 YR - 1993 ED - 19930803 RD - 20151119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=8319169 <679. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 8518376 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Theil DR AU - Stanley TE 3rd AU - White WD AU - Goodman DK AU - Glass PS AU - Bai SA AU - Jacobs JR AU - Reves JG FA - Theil, D R FA - Stanley, T E 3rd FA - White, W D FA - Goodman, D K FA - Glass, P S FA - Bai, S A FA - Jacobs, J R FA - Reves, J G IN - Theil, D R. Heart Center of Duke University School of Medicine, Durham, NC 27710. TI - Midazolam and fentanyl continuous infusion anesthesia for cardiac surgery: a comparison of computer-assisted versus manual infusion systems. SO - Journal of Cardiothoracic & Vascular Anesthesia. 7(3):300-6, 1993 Jun AS - J Cardiothorac Vasc Anesth. 7(3):300-6, 1993 Jun NJ - Journal of cardiothoracic and vascular anesthesia PI - Journal available in: Print PI - Citation processed from: Print JC - a6i, 9110208 IO - J. Cardiothorac. Vasc. Anesth. SB - Index Medicus CP - United States MH - *Anesthesia, Intravenous MH - Blood Pressure/ph [Physiology] MH - *Coronary Artery Bypass MH - Double-Blind Method MH - Drug Therapy, Computer-Assisted/is [Instrumentation] MH - Female MH - *Fentanyl/ad [Administration & Dosage] MH - Fentanyl/bl [Blood] MH - Fentanyl/pk [Pharmacokinetics] MH - Forecasting MH - Heart Rate/ph [Physiology] MH - Humans MH - *Infusion Pumps MH - Intubation, Intratracheal MH - Male MH - *Midazolam/ad [Administration & Dosage] MH - Midazolam/bl [Blood] MH - Midazolam/pk [Pharmacokinetics] MH - Middle Aged MH - Monitoring, Intraoperative MH - Placebos MH - Time Factors AB - Continuous infusion of intravenous anesthetics can be achieved either by a manually controlled infusion (MCI) pump, or by a computer-assisted continuous infusion (CACI) pharmacokinetic model-driven infusion system. Randomized double-blind comparisons of the two infusion systems for general anesthesia were performed in 24 patients undergoing coronary artery bypass grafting. Patients were allocated to receive continuous infusions of midazolam and fentanyl by either a MCI device or CACI. Midazolam and fentanyl infusions were independently titrated to maintain hemodynamic stability, defined as mean arterial pressure (MAP) and heart rate (HR) within 20% of baseline values. As directed by the study design, comparable hemodynamic control was achieved in both groups. Mean plasma fentanyl concentrations measured at specific timepoints were similar between groups. The plasma midazolam level for induction was 196 +/- 139 ng/mL in the CACI group and 300 +/- 128 ng/mL in the MCI group, and the fentanyl level was similar in both groups, 6.7 +/- 1.9 ng/mL in CACI and 6.3 +/- 4.6 ng/mL in the MCI group. The drug levels were lower (P < or = .05) for midazolam during maintenance of anesthesia and similar for fentanyl during the maintenance of anesthesia. In the MCI group, the average duration of anesthesia was 246.5 +/- 35.0 minutes, with a mean total fentanyl dose of 30.27 +/- 11.14 micrograms/kg. In the CACI group, the average duration of anesthesia was 230.8 +/- 44.1 minutes, with a mean total fentanyl dose of 34.61 +/- 5.40 micrograms/kg (P > 0.05 for comparisons between groups for duration of anesthesia and total fentanyl dose).(ABSTRACT TRUNCATED AT 250 WORDS) RN - 0 (Placebos) RN - R60L0SM5BC (Midazolam) RN - UF599785JZ (Fentanyl) IS - 1053-0770 IL - 1053-0770 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 8518376 [pubmed] PP - ppublish LG - English DP - 1993 Jun DC - 19930729 EZ - 1993/06/01 00:00 DA - 1993/06/01 00:01 DT - 1993/06/01 YR - 1993 ED - 19930729 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=8518376 <680. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 1295026 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Lyons MK AU - Kelly PJ FA - Lyons, M K FA - Kelly, P J IN - Lyons, M K. Department of Neurological Surgery, Mayo Clinic, Rochester, Minn. TI - Computer-assisted stereotactic biopsy and volumetric resection of thalamic pilocytic astrocytomas. Report of 23 cases. SO - Stereotactic & Functional Neurosurgery. 59(1-4):100-4, 1992 AS - Stereotact Funct Neurosurg. 59(1-4):100-4, 1992 NJ - Stereotactic and functional neurosurgery PI - Journal available in: Print PI - Citation processed from: Print JC - sfn, 8902881 IO - Stereotact Funct Neurosurg SB - Index Medicus CP - Switzerland MH - Adolescent MH - Adult MH - *Astrocytoma/pa [Pathology] MH - *Astrocytoma/su [Surgery] MH - Biopsy MH - *Brain Neoplasms/pa [Pathology] MH - *Brain Neoplasms/su [Surgery] MH - Child MH - Diagnosis, Computer-Assisted MH - Female MH - Humans MH - Male MH - Stereotaxic Techniques MH - *Thalamic Diseases/pa [Pathology] MH - *Thalamic Diseases/su [Surgery] AB - Twenty-three cases of pathologically verified thalamic pilocytic astrocytomas diagnosed at computer-assisted stereotactic biopsy and/or volumetric resection at the Mayo Clinic between January 1985 and October 1990 were reviewed. Computer-assisted stereotactic volumetric resection was performed in 19 patients. Postoperative imaging demonstrated no residual contrast-enhancing tumor in 14 patients and a small amount of contrast-enhancing tumor (less than 5% of the original tumor volume) in 5 patients. Biopsy only was performed in 4 patients: 2 with primarily cystic tumors successfully treated with stereotactic instillation of 32P, and 2 patients with stable (nonprogressive) deficits. There was 1 operative death; a patient with tumor extending into the midbrain became comatose and died 10 days after surgery. The remaining 22 patients are alive and well. Computer-assisted stereotactic volumetric resection of thalamic pilocytic astrocytomas can be performed with low morbidity and a favorable long-term prognosis. IS - 1011-6125 IL - 1011-6125 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 1295026 [pubmed] PP - ppublish LG - English DP - 1992 DC - 19930413 EZ - 1992/01/01 00:00 DA - 1992/01/01 00:01 DT - 1992/01/01 YR - 1992 ED - 19930413 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=1295026 <681. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 1490537 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Gilliland A AU - Mills KA AU - Steele K FA - Gilliland, A FA - Mills, K A FA - Steele, K IN - Gilliland, A. Department of General Practice, Queen's University of Belfast, Dunluce Health Centre. TI - General practitioner records on computer--handle with care. CM - Comment in: Fam Pract. 1993 Dec;10(4):474; PMID: 8031369 SO - Family Practice. 9(4):441-50, 1992 Dec AS - Fam Pract. 9(4):441-50, 1992 Dec NJ - Family practice PI - Journal available in: Print PI - Citation processed from: Print JC - 8500875, fam IO - Fam Pract SB - Index Medicus CP - England MH - *Family Practice/og [Organization & Administration] MH - Humans MH - *Medical Records/st [Standards] MH - *Medical Records Systems, Computerized AB - This 1 year prospective study involved nine general practitioners in an urban health centre who routinely record all patient contacts on computer. The study determines by comparison with a manual record how accurately doctors record laboratory investigations on computer and compares the effectiveness of three interventions in improving the completeness of computerized recording of presenting symptoms, problems/diagnoses and laboratory investigations. Recording was analysed for 1 month prior to and for two 1 month periods following each intervention. A control group was used. A total of 7983 patient contacts were analysed. Intervention led to an improvement in the recording of presenting symptoms and problems/diagnoses. Recording of investigations on the computer showed no improvement, remaining at one-third of the total in the treatment room book for both study and control doctors. The effectiveness of the different forms of intervention depended on both the aspect of the consultation considered and the familiarity of individual doctors with the method of data collection. Aspects considered less important required greater intervention to bring about a marked improvement, as did doctors relatively new to the practice. It may not be possible to get all aspects of the consultation recorded with the same degree of accuracy. This has implications for the accuracy of retrospective studies dependent on existing computerized data. IS - 0263-2136 IL - 0263-2136 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 1490537 [pubmed] PP - ppublish LG - English DP - 1992 Dec DC - 19930226 EZ - 1992/12/01 00:00 DA - 1992/12/01 00:01 DT - 1992/12/01 YR - 1992 ED - 19930226 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=1490537 <682. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 1595910 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Hausen B AU - Schafers HJ AU - Rohde R AU - Haverich A FA - Hausen, B FA - Schafers, H J FA - Rohde, R FA - Haverich, A IN - Hausen, B. Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Germany. TI - Clinical evaluation of transtracheal Doppler for continuous cardiac output estimation. CM - Comment in: Anesth Analg. 1992 Jun;74(6):790-2; PMID: 1595908 SO - Anesthesia & Analgesia. 74(6):800-4, 1992 Jun AS - Anesth Analg. 74(6):800-4, 1992 Jun NJ - Anesthesia and analgesia PI - Journal available in: Print PI - Citation processed from: Print JC - 4r8, 1310650 IO - Anesth. Analg. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Blood Flow Velocity MH - *Cardiac Output/ph [Physiology] MH - Cardiac Surgical Procedures/mt [Methods] MH - Computer Systems MH - Evaluation Studies as Topic MH - Humans MH - *Intubation, Intratracheal/mt [Methods] MH - Middle Aged MH - Monitoring, Physiologic/mt [Methods] MH - Thermodilution/mt [Methods] MH - *Ultrasonics AB - A newly developed transtracheal Doppler (TTD) computer for cardiac output determination was studied in nine patients after open heart surgery (coronary artery bypass grafting, n = 4; mitral valve replacement, n = 5). The measurements were compared with those simultaneously obtained by thermodilation. Doppler signals were adequate in 78% of the patients studied. Limited correlation between both methods (r = 0.248; r2 = 0.0615; mean of difference, 1.714 +/- 1.67 L/min; limits of agreement, -1.6 to 5.0 L/min) was found. The large difference in cardiac output readings between TTD and thermodilation may be due to (a) false angles of the ultrasound beam in relation to the aortic wall and blood flow or (b) misplacement of the ultrasound head and underestimation of the aortic lumen. Patients must be completely sedated and paralyzed to prohibit artifacts. Routine patient care can interfere with continuous measurements. Cardiac output determinations by TTD are limited to the period during which the trachea is intubated with the special TTD tube. We conclude that the TTD system does not offer accurate cardiac output determinations and that the routine use of this device is not practical. IS - 0003-2999 IL - 0003-2999 PT - Clinical Trial PT - Comparative Study PT - Journal Article ID - 1595910 [pubmed] PP - ppublish LG - English DP - 1992 Jun DC - 19920626 EZ - 1992/06/01 00:00 DA - 1992/06/01 00:01 DT - 1992/06/01 YR - 1992 ED - 19920626 RD - 20071115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=1595910 <683. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 2520633 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Murchie CJ AU - Kenny GN FA - Murchie, C J FA - Kenny, G N IN - Murchie, C J. University Department of Anaesthesia, Glasgow Royal Infirmary, Scotland, United Kingdom. TI - Comparison among manual, computer-assisted, and closed-loop control of blood pressure after cardiac surgery. SO - Journal of Cardiothoracic Anesthesia. 3(1):16-9, 1989 Feb AS - J Cardiothorac Anesth. 3(1):16-9, 1989 Feb NJ - Journal of cardiothoracic anesthesia PI - Journal available in: Print PI - Citation processed from: Print JC - 8709732, a7b IO - J Cardiothorac Anesth SB - Index Medicus CP - United States MH - Blood Pressure MH - Cardiac Surgical Procedures/ae [Adverse Effects] MH - Cardiac Surgical Procedures/nu [Nursing] MH - *Cardiac Surgical Procedures MH - Data Display MH - *Drug Therapy, Computer-Assisted MH - Equipment Design MH - Humans MH - Hypertension/nu [Nursing] MH - *Hypertension/pc [Prevention & Control] MH - *Infusion Pumps MH - Intensive Care Units MH - *Nitroprusside/ad [Administration & Dosage] MH - Postoperative Complications/nu [Nursing] MH - *Postoperative Complications/pc [Prevention & Control] AB - Forty-five patients who required vasodilator therapy for systemic arterial hypertension following cardiac surgery were randomly allocated to receive: (1) manual control of a sodium nitroprusside (SNP) infusion; (2) computer-assisted control where the nurse was provided with a color graphical display of performance; or (3) automatic closed-loop control. Limits of acceptable systolic pressure were prescribed for each patient, and the percentage time spent outside these limits was calculated for each patient. The closed-loop computer system (CLCS) produced significantly better control than either manual or computer-assisted systems for the time spent outside the prescribed limits (P less than 0.001), and better control for the time spent outside the limits +/- 10 mmHg (manual P less than 0.001; assisted P less than 0.01). While the CLCS proved more satisfactory than manual control for the limits +/- 20 mmHg and +/- 30 mmHg (+/- 20 mmHg P less than 0.001; +/- 30 mmHg P less than 0.01), there was no significant difference in the quality of control between the CLCS and computer-assisted systems for these limits. The results suggest that the quality of blood pressure control achieved by nurses can be improved by providing them with a clear graphical display of their performance. Better control of blood pressure should reduce the adverse effects of hypotension and hypertension following cardiac surgery. RN - 169D1260KM (Nitroprusside) IS - 0888-6296 IL - 0888-6296 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 2520633 [pubmed] PP - ppublish LG - English DP - 1989 Feb DC - 19920615 EZ - 1989/02/01 00:00 DA - 1989/02/01 00:01 DT - 1989/02/01 YR - 1989 ED - 19920615 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=2520633 <684. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 1547194 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Mack WJ AU - Selzer RH AU - Pogoda JM AU - Lee PL AU - Shircore AM AU - Azen SP AU - Blankenhorn DH FA - Mack, W J FA - Selzer, R H FA - Pogoda, J M FA - Lee, P L FA - Shircore, A M FA - Azen, S P FA - Blankenhorn, D H IN - Mack, W J. Department of Preventive Medicine, University of Southern California, Los Angeles. IR - Selzer RH IA - Selzer, R H. NASA JPL TI - Comparison of computer- and human-derived coronary angiographic end-point measures for controlled therapy trials. SO - Arteriosclerosis & Thrombosis. 12(3):348-56, 1992 Mar AS - Arterioscler Thromb. 12(3):348-56, 1992 Mar NJ - Arteriosclerosis and thrombosis : a journal of vascular biology PI - Journal available in: Print PI - Citation processed from: Print JC - az1, 9101388 IO - Arterioscler. Thromb. SB - Index Medicus SB - National Aeronautics and Space Administration (NASA) Journals CP - United States MH - Adult MH - Colestipol/tu [Therapeutic Use] MH - Combined Modality Therapy MH - *Computers MH - *Coronary Angiography/mt [Methods] MH - *Coronary Artery Disease/dg [Diagnostic Imaging] MH - Coronary Artery Disease/dh [Diet Therapy] MH - Coronary Artery Disease/dt [Drug Therapy] MH - Humans MH - Male MH - Middle Aged MH - Niacin/tu [Therapeutic Use] KW - NASA Center JPL; NASA Discipline Musculoskeletal AB - The Cholesterol Lowering Atherosclerosis Study, a randomized angiographic clinical trial, demonstrated the beneficial effect of niacin/colestipol plus diet therapy on coronary atherosclerosis. Outcome was determined by panel-based estimates (viewed in both still and cine modes) of percent stenosis severity and change in native artery and bypass graft lesions. Computer-based quantitative coronary angiography (QCA) was also used to measure lesion and bypass graft stenosis severity and change in individual frames closely matched in orientation, opacification, and cardiac phase. Both methods jointly evaluated 350 nonoccluded lesions. The correlation between QCA and panel estimates of lesion size was 0.70 (p less than 0.0001) and for change in lesion size was 0.28 (p = 0.002). Agreement between the two methods in classifying lesion changes (i.e., regression, unchanged, or progression) occurred for 60% (210 of 350) of the lesions kappa +/- SEM = 0.20 +/- 0.05, p less than 0.001). The panel identified 442 nonoccluded lesions for which QCA stenosis measurements could not be obtained. Lesions not measurable by QCA included those with stenosis greater than 85% that could not be reliably edge tracked, segments with diffuse or ecstatic disease that had no reliable reference diameter, and segments for which matched frames could not be located. Seventy-nine lesions, the majority between 21% and 40% stenosis, were identified and measured by QCA but were not identified by the panel. This comparison study demonstrates the need to consider available angiographic measurement methods in relation to the goals of their use. RN - 2679MF687A (Niacin) RN - K50N755924 (Colestipol) IS - 1049-8834 IL - 1049-8834 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. ID - 1547194 [pubmed] PP - ppublish GI - No: R01-HL-23619 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English DP - 1992 Mar DC - 19920420 EZ - 1992/03/01 00:00 DA - 1992/03/01 00:01 DT - 1992/03/01 YR - 1992 ED - 19920420 RD - 20161123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=1547194 <685. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 1758315 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Mangione S AU - Nieman LZ AU - Greenspon LW AU - Margulies H FA - Mangione, S FA - Nieman, L Z FA - Greenspon, L W FA - Margulies, H IN - Mangione, S. Department of Medicine, Medical College of Pennsylvania, Philadelphia 19129. TI - A comparison of computer-assisted instruction and small-group teaching of cardiac auscultation to medical students. SO - Medical Education. 25(5):389-95, 1991 Sep AS - Med Educ. 25(5):389-95, 1991 Sep NJ - Medical education PI - Journal available in: Print PI - Citation processed from: Print JC - mz3, 7605655 IO - Med Educ SB - Index Medicus CP - England MH - Clinical Competence MH - *Computer-Assisted Instruction/mt [Methods] MH - *Education, Medical, Undergraduate MH - *Heart Auscultation MH - Humans MH - Philadelphia MH - *Teaching/mt [Methods] AB - Cardiac auscultation is suffering from declining interest, caused by competing diagnostic technology and inadequate training of doctors. Computer-assisted instruction (CAI) supporting graphics and digitized sound could be ideally suited for teaching and sharpening this skill. To evaluate this premise we randomized 35 third-year medical students to 3 hours of seminar teaching plus the use of audiotapes (group 1), the self-use of a MacIntosh-based CAI (group 2), or both (group 3). All students took a pre- and post-test consisting of eight pre-recorded cardiac events and were also assessed for computer anxiety. Although there were no significant differences between pre- and post-tests for each group and among groups, group 1 had a 4.5% deterioration in its diagnostic score compared to the 7.2% and 3.2% improvements of groups 2 and 3 respectively. Group 2 used the CAI significantly more than group 3. We conclude that CAI is at least as effective as seminars in teaching cardiac auscultation to third-year medical students. IS - 0308-0110 IL - 0308-0110 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 1758315 [pubmed] PP - ppublish LG - English DP - 1991 Sep DC - 19920204 EZ - 1991/09/01 00:00 DA - 1991/09/01 00:01 DT - 1991/09/01 YR - 1991 ED - 19920204 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=1758315 <686. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 1744329 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Crew AD AU - Stoodley KD AU - Lu R AU - Old S AU - Ward M FA - Crew, A D FA - Stoodley, K D FA - Lu, R FA - Old, S FA - Ward, M IN - Crew, A D. Yorkshire Regional Cardiothoracic Centre, Killingbeck Hospital, Leeds, UK. TI - Preliminary clinical trials of a computer-based cardiac arrest alarm. SO - Intensive Care Medicine. 17(6):359-64, 1991 AS - Intensive Care Med. 17(6):359-64, 1991 NJ - Intensive care medicine PI - Journal available in: Print PI - Citation processed from: Print JC - h2j, 7704851 IO - Intensive Care Med SB - Index Medicus CP - United States MH - Algorithms MH - Artifacts MH - Blood Pressure MH - Child, Preschool MH - *Diagnosis, Computer-Assisted/is [Instrumentation] MH - *Equipment Failure MH - *Heart Arrest/di [Diagnosis] MH - Heart Arrest/ep [Epidemiology] MH - Heart Arrest/pp [Physiopathology] MH - Heart Rate MH - Humans MH - Middle Aged MH - *Monitoring, Physiologic/is [Instrumentation] MH - Predictive Value of Tests AB - The use of a high reliability cardiac arrest alarm utilising the continuously monitored values of patient heart rate and mean arterial blood pressure is described, based on a sample of 167 patients monitored for a total of 5116 h. The analogue heart rate and mean blood pressure signals are sampled at 1 s intervals, and a smoothing algorithm is applied to each of the resulting series which rejects artefacts, and identifies slope and step changes in each. Certain combinations of events in the 2 series, occurring within a preset time window, determine whether a cardiac arrest alarm or warning signal should be activated by the system. A total of 30 acute events occurring in 14 patients during the course of the study were each identified within 10 s. No cardiac arrest event was misdiagnosed by the algorithm during the period of the study. The algorithm also generates warnings which may have predictive value, and which will be the subject of further research. A final false alarm rate of about 1/200 h of monitoring was observed in adults (1/50 h in children), with evidence that these rates could be substantially improved. IS - 0342-4642 IL - 0342-4642 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 1744329 [pubmed] PP - ppublish LG - English DP - 1991 DC - 19920116 EZ - 1991/01/01 00:00 DA - 1991/01/01 00:01 DT - 1991/01/01 YR - 1991 ED - 19920116 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=1744329 <687. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 1683929 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - van der Lei J AU - Musen MA AU - van der Does E AU - Man in 't Veld AJ AU - van Bemmel JH FA - van der Lei, J FA - Musen, M A FA - van der Does, E FA - Man in 't Veld, A J FA - van Bemmel, J H IN - van der Lei, J. Department of Medical Informatics, Erasmus University, Rotterdam, Netherlands. TI - Comparison of computer-aided and human review of general practitioners' management of hypertension. SO - Lancet. 338(8781):1504-8, 1991 Dec 14 AS - Lancet. 338(8781):1504-8, 1991 Dec 14 NJ - Lancet (London, England) PI - Journal available in: Print PI - Citation processed from: Print JC - 2985213r, l0s, 0053266 IO - Lancet SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - Adult MH - Aged MH - Aged, 80 and over MH - Antihypertensive Agents/tu [Therapeutic Use] MH - *Decision Making, Computer-Assisted MH - *Family Practice/st [Standards] MH - Female MH - Humans MH - *Hypertension/dt [Drug Therapy] MH - Male MH - *Medical Audit/mt [Methods] MH - Middle Aged MH - Netherlands MH - *Peer Review MH - Sampling Studies MH - Sensitivity and Specificity MH - Software Design AB - Computer programs that automatically review decisions can help physicians provide better patient care. In the Netherlands, the ELIAS computer information system has replaced paper medical records in some general practices. We have written a computer program called 'HyperCritic' that audits general practitioners' management of patients with essential hypertension by taking patient-specific data from the ELIAS system. We investigated whether the computer-based medical records contain sufficient information to generate critiques, and compared the limitations of audit by hypercritic with those of review by a panel of eight physicians. Hypercritic and the physicians independently reviewed the medical records of 20 randomly selected patients with hypertension and commented on the decisions made at each of 243 patient visits. Of 468 comments on patient management, 260 were judged correct by six or more of the physicians; hypercritic also made 118 of these 260 comments. The main reasons why the program did not produce the other 142 comments were: insufficient data in the computer-based medical record; absence of sufficient medical consensus; and omissions in the database of hypercritic. Calculation of an "index of merit" ([sensitivity + specificity] - 1) for individual reviewers showed that hypercritic performed better (index of merit 0.62) in its limited domain than did physician reviewers (0.3-0.56). At least in hypertension management, automated review of computer-based medical records compares favourably with review by physicians. Further development of computer-aided clinical audit requires the introduction of computer-based medical records that capture the reasoning of physicians, and of widely accepted practice guidelines. RN - 0 (Antihypertensive Agents) IS - 0140-6736 IL - 0140-6736 DI - 0140-6736(91)92311-O PT - Clinical Trial PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. ID - 1683929 [pubmed] ID - 0140-6736(91)92311-O [pii] PP - ppublish GI - No: LM05157 Organization: (LM) *NLM NIH HHS* Country: United States LG - English DP - 1991 Dec 14 DC - 19920115 EZ - 1991/12/14 00:00 DA - 1991/12/14 00:01 DT - 1991/12/14 YR - 1991 ED - 19920115 RD - 20150616 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=1683929 <688. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 1906905 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Brogan WC 3rd AU - Lange RA AU - Kim AS AU - Moliterno DJ AU - Hillis LD FA - Brogan, W C 3rd FA - Lange, R A FA - Kim, A S FA - Moliterno, D J FA - Hillis, L D IN - Brogan, W C 3rd. Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75235. TI - Alleviation of cocaine-induced coronary vasoconstriction by nitroglycerin. SO - Journal of the American College of Cardiology. 18(2):581-6, 1991 Aug AS - J Am Coll Cardiol. 18(2):581-6, 1991 Aug NJ - Journal of the American College of Cardiology PI - Journal available in: Print PI - Citation processed from: Print JC - h50, 8301365 IO - J. Am. Coll. Cardiol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Administration, Intranasal MH - Administration, Sublingual MH - Aged MH - Cardiac Catheterization MH - Cocaine/ad [Administration & Dosage] MH - *Cocaine/ae [Adverse Effects] MH - Coronary Angiography MH - Coronary Artery Disease/pp [Physiopathology] MH - *Coronary Vessels/de [Drug Effects] MH - Female MH - Humans MH - Male MH - Middle Aged MH - Nitroglycerin/ad [Administration & Dosage] MH - *Nitroglycerin/tu [Therapeutic Use] MH - *Vasoconstriction/de [Drug Effects] AB - Cocaine induces vasoconstriction of epicardial coronary arteries in patients with and without coronary artery disease, and this vasoconstriction is particularly marked in segments narrowed by atherosclerosis. To assess the effect of nitroglycerin on cocaine-induced coronary vasoconstriction, computer-assisted quantitative analysis was performed on non-diseased and diseased coronary artery segments in 23 patients (18 men, 5 women, aged 43 to 65 years) 1) at baseline, 2) after administration of intranasal saline solution (in 8 patients) or 2 mg/kg of cocaine (in 15 patients), and then 3) after administration of sublingual placebo (in 6 patients) or 0.4 or 0.8 mg of nitroglycerin (in 9 patients) in the 15 patients given cocaine. In response to cocaine administration, coronary artery cross-sectional area decreased 22 +/- 7% (mean +/- SD) in non-diseased segments (p less than 0.05) and 45 +/- 18% in diseased segments (p less than 0.02). The magnitude of vasoconstriction was greater (p = 0.01) in the diseased segments. Sublingual nitroglycerin abolished the vasoconstriction in both non-diseased and diseased segments. Thus, nitroglycerin alleviates cocaine-induced vasoconstriction in patients with coronary artery disease. RN - G59M7S0WS3 (Nitroglycerin) RN - I5Y540LHVR (Cocaine) IS - 0735-1097 IL - 0735-1097 DI - 0735-1097(91)90617-I PT - Clinical Trial PT - Controlled Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. ID - 1906905 [pubmed] ID - 0735-1097(91)90617-I [pii] PP - ppublish GI - No: HL-17669 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English DP - 1991 Aug DC - 19910826 EZ - 1991/08/01 00:00 DA - 1991/08/01 00:01 DT - 1991/08/01 YR - 1991 ED - 19910826 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=1906905 <689. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 2055059 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Assmann R AU - Heidelmeyer CF AU - Trampisch HJ AU - Mottaghy K AU - Versprille A AU - Sandmann W AU - Falke KJ FA - Assmann, R FA - Heidelmeyer, C F FA - Trampisch, H J FA - Mottaghy, K FA - Versprille, A FA - Sandmann, W FA - Falke, K J IN - Assmann, R. Zentrum fur Anaesthesiologie, Universitat Dusseldorf, FRG. TI - Right ventricular function assessed by thermodilution technique during apnea and mechanical ventilation. SO - Critical Care Medicine. 19(6):810-7, 1991 Jun AS - Crit Care Med. 19(6):810-7, 1991 Jun NJ - Critical care medicine PI - Journal available in: Print PI - Citation processed from: Print JC - dtf, 0355501 IO - Crit. Care Med. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Aged MH - Animals MH - *Apnea/pp [Physiopathology] MH - Cardiac Output/ph [Physiology] MH - Humans MH - Male MH - Middle Aged MH - Reproducibility of Results MH - *Respiration, Artificial MH - Sheep MH - Stroke Volume/ph [Physiology] MH - *Thermodilution MH - *Ventricular Function, Right/ph [Physiology] AB - OBJECTIVES: To evaluate strategies for thermodilution-based measurement of cardiac output and right ventricular (RV) ejection fraction and to assess the effects of controlled mechanical ventilation in patients. Furthermore, to compare strategy-associated reproducibility with reference values obtained during long-term apnea. AB - DESIGN: Crossover trial in patients; reference values from apneic animals. AB - SETTING: University ICU and physiology laboratory. AB - PATIENTS: Six consecutive male ICU patients (48 to 70 yrs) after major abdominal vascular surgery. AB - ANIMALS: two adult female sheep. AB - INTERVENTIONS: Three ventilatory rates (8, 16, and 24 cycles/min) and 15-sec periods of apnea were selected for measurements in patients. In animals, continuous apnea was achieved with extracorporeal CO2 removal and apneic oxygenation. AB - MEASUREMENTS: Measurements were performed using an appropriate pulmonary artery catheter and an ejection fraction/cardiac output computer prototype. The thermal indicator was injected automatically at four defined points of the ventilatory cycle, but triggered manually during apnea. AB - MAIN RESULTS: At 8 cycles/min, there was a wide mean range of cyclic variable modulation, with a coefficient of variation of 11.6% and 23.2% for cardiac output and RV ejection fraction, respectively. Allowing for ventilatory phase or changing from 8 to 16 cycles/min reduced errors by half. Combining both procedures resulted in a coefficient of variation of 4.7% and 6.6% for cardiac output and RV ejection fraction, respectively. The best coefficient of variation values obtained during 15 secs of apnea in patients approached those variations in experimental apnea (coefficient of variation of 2.1% and 4.5% for cardiac output and RV ejection fraction, respectively). AB - CONCLUSIONS: At low ventilatory rates, best results are achieved by averaging four phase-selected measurements. One-point measurements were less accurate and random point measurements less reproducible. IS - 0090-3493 IL - 0090-3493 PT - Clinical Trial PT - Controlled Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 2055059 [pubmed] PP - ppublish LG - English DP - 1991 Jun DC - 19910729 EZ - 1991/06/01 00:00 DA - 1991/06/01 00:01 DT - 1991/06/01 YR - 1991 ED - 19910729 RD - 20140729 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=2055059 <690. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 2097305 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Jost S AU - Deckers J AU - Rafflenbeul W AU - Hecker H AU - Reiber JH AU - Nikutta P AU - Wiese B AU - Hugenholtz P AU - Lichtlen P FA - Jost, S FA - Deckers, J FA - Rafflenbeul, W FA - Hecker, H FA - Reiber, J H FA - Nikutta, P FA - Wiese, B FA - Hugenholtz, P FA - Lichtlen, P IN - Jost, S. Department of Cardiology, Hannover Medical School, Germany. TI - International nifedipine trial on anti-atherosclerotic therapy (INTACT)--methodologic implications and results of a coronary angiographic follow-up study using computer-assisted film analysis. SO - International Journal of Cardiac Imaging. 6(2):117-33, 1990-1991 AS - Int J Card Imaging. 6(2):117-33, 1990-1991 NJ - International journal of cardiac imaging PI - Journal available in: Print PI - Citation processed from: Print JC - ijd, 8600426 IO - Int J Card Imaging SB - Index Medicus CP - Netherlands MH - Cineangiography/mt [Methods] MH - *Coronary Angiography MH - Coronary Artery Disease/dg [Diagnostic Imaging] MH - *Coronary Artery Disease/dt [Drug Therapy] MH - Double-Blind Method MH - Humans MH - *Image Processing, Computer-Assisted MH - *Nifedipine/tu [Therapeutic Use] MH - Prospective Studies AB - Animal experiments demonstrated a significant suppressive effect of various calcium channel blockers on the formation of atherosclerotic lesions. Therefore, a prospective, placebo-controlled, randomized, double blind multicenter study was performed to investigate the inhibitory influence of the calcium channel blocker nifedipine (80 mg/day) on the progression of coronary artery disease in man. Study endpoints were changes of coronary morphology documented by coronary angiography with particular respect to the formation of new coronary stenoses. In 348 out of 425 patients included in the study, coronary angiograms were repeated after three years. The angiograms were standardized by induction of a maximal coronary vasodilation with high doses of nitrates and by using absolutely identical angiographic projections. Quantitative analysis of coronary cineangiograms was performed with the computer-assisted contour detection system CAAS. Parameters were mean and minimal diameter of all segments and minimal stenosis diameter, percent diameter stenosis, length and plaque area of all stenoses. Continuous intake of study medication was registered in 282 patients, 134 on nifedipine and 148 patients on placebo. In these patients, a total of 3808 coronary segments with 893 stenoses (greater than or equal to 20% diameter reduction in at least one angiographic projection) were compared on the baseline and follow-up cineangiograms. The changes in all angiographic parameters analyzed averaged over all patients by considering all angiographic projections analyzed, indicated significant progression of the disease (p less than 0.006). The average changes in all parameters were even about three times more profound, when in the individual patients only the respective projections indicating the maximal changes were considered for the calculation (p less than 0.001). However, with neither of these two analysis modes, the differences in progression between the treatment groups were statistically significant. In the follow-up angiograms, a total of 196 new coronary lesions (185 stenoses, 11 occlusions) were found at previously normal arterial sites. In patients on nifedipine, an average of only 0.58 new lesions per patient were detected versus 0.80 lesions per patient on placebo (-27%; p = 0.031). INTACT is the first prospective angiographic trial on the progression of coronary artery disease using computer-assisted quantitative coronary angiography in such a high number of patients. All parameters analyzed indicated significant progression of coronary artery sclerosis. Nifedipine had no influence on the progression of preexisting coronary stenoses, but inhibited significantly the formation of new angiographically recognizable lesions. Further prospective coronary angiographic trials with calcium channel blockers using a comparably exact method are needed to confirm the results of this study. RN - I9ZF7L6G2L (Nifedipine) IS - 0167-9899 IL - 0167-9899 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial ID - 2097305 [pubmed] PP - ppublish LG - English DP - 1990-1991 DC - 19910725 EZ - 1990/01/01 00:00 DA - 1990/01/01 00:01 DT - 1990/01/01 YR - 1990 ED - 19910725 RD - 20161123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=2097305 <691. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 2254543 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Grill HP AU - Brinker JA AU - Taube JC AU - Walford GD AU - Midei MG AU - Flaherty JT AU - Weiss JL FA - Grill, H P FA - Brinker, J A FA - Taube, J C FA - Walford, G D FA - Midei, M G FA - Flaherty, J T FA - Weiss, J L IN - Grill, H P. Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland. TI - Contrast echocardiographic mapping of collateralized myocardium in humans before and after coronary angioplasty. CM - Comment in: J Am Coll Cardiol. 1990 Dec;16(7):1601-2; PMID: 2254544 SO - Journal of the American College of Cardiology. 16(7):1594-600, 1990 Dec AS - J Am Coll Cardiol. 16(7):1594-600, 1990 Dec NJ - Journal of the American College of Cardiology PI - Journal available in: Print PI - Citation processed from: Print JC - h50, 8301365 IO - J. Am. Coll. Cardiol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - *Angioplasty, Balloon, Coronary MH - *Collateral Circulation/ph [Physiology] MH - *Coronary Circulation/ph [Physiology] MH - *Coronary Disease/dg [Diagnostic Imaging] MH - Coronary Disease/th [Therapy] MH - *Coronary Vessels/dg [Diagnostic Imaging] MH - *Echocardiography MH - Female MH - Humans MH - *Image Processing, Computer-Assisted MH - Male MH - Middle Aged AB - Conventional coronary arteriography is able to demonstrate the presence of coronary collateral vessels but cannot delineate the specific region of myocardium to which they supply blood. To test the hypothesis that contrast echocardiography can specifically identify collateralized myocardium, contrast echocardiographic perfusion "maps" were compared in patients with (n = 12) and without (n = 12) angiographic evidence of coronary collateral flow, both before and after coronary angioplasty. Contrast echocardiographic images of the mid-left ventricle in the short-axis view at end-diastole were obtained after separate injections of a sonicated contrast agent into both the right and the left coronary arteries. A computer-based contouring system was used to determine the individual areas of myocardium perfused by each of the two coronary arteries and then to superimpose the images of the two perfusion beds. The resulting area of overlapping perfusion represented myocardium receiving blood flow from both coronary systems and was defined as collateralized myocardium. To normalize for heart size, overlap area was expressed as a percent of total myocardial area, which was the area between endocardium and epicardium in the short-axis view. To adjust for differences in vascular distribution, overlap area was expressed as a percent of the perfusion area of the recipient vessel. In patients with angiographic collateral flow, the recipient vessel was that vessel receiving the collateral flow. In patients without angiographic collateral flow, the right coronary artery was considered the recipient vessel. Overlap area was 1.3 +/- 0.4% of total myocardial area and 6.6 +/- 1.7% of recipient vessel area in patients without angiographic evidence of collateral flow compared with 30.6 +/- 2.5% and 89.2 +/- 6.4%, respectively, in patients with angiographic collateral flow (p less than 0.001 for both). In four patients in whom angiographic collateral flow was abolished by angioplasty, overlap area decreased from 30.3 +/- 5.3% to 6.8 +/- 2.7% of total myocardial area and from 100% to 18.5 +/- 5.4% of recipient vessel area (p less than 0.05 for both). Thus, contrast echocardiography is able to map the specific myocardial territory perfused by coronary collateral flow and document an immediate reduction in perfusion in this territory when collateral flow is abolished by angioplasty. IS - 0735-1097 IL - 0735-1097 DI - 0735-1097(90)90306-A PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. ID - 2254543 [pubmed] ID - 0735-1097(90)90306-A [pii] PP - ppublish GI - No: HL17655-15 Organization: (HL) *NHLBI NIH HHS* Country: United States No: R01 HL-33385 Organization: (HL) *NHLBI NIH HHS* Country: United States No: T32HL07227 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English DP - 1990 Dec DC - 19910124 EZ - 1990/12/01 00:00 DA - 1990/12/01 00:01 DT - 1990/12/01 YR - 1990 ED - 19910124 RD - 20161123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=2254543 <692. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 2123904 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Van Lierde J AU - De Geest H AU - Verstraete M AU - Van de Werf F FA - Van Lierde, J FA - De Geest, H FA - Verstraete, M FA - Van de Werf, F IN - Van Lierde, J. Division of Cardiology, University of Leuven, Belgium. TI - Angiographic assessment of the infarct-related residual coronary stenosis after spontaneous or therapeutic thrombolysis. CM - Comment in: J Am Coll Cardiol. 1990 Dec;16(7):1550-2; PMID: 2123905 SO - Journal of the American College of Cardiology. 16(7):1545-9, 1990 Dec AS - J Am Coll Cardiol. 16(7):1545-9, 1990 Dec NJ - Journal of the American College of Cardiology PI - Journal available in: Print PI - Citation processed from: Print JC - h50, 8301365 IO - J. Am. Coll. Cardiol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - Angiography, Digital Subtraction MH - Constriction, Pathologic/dg [Diagnostic Imaging] MH - *Coronary Angiography MH - Female MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/dg [Diagnostic Imaging] MH - *Myocardial Infarction/dt [Drug Therapy] MH - *Thrombolytic Therapy MH - *Tissue Plasminogen Activator/tu [Therapeutic Use] MH - Vascular Patency AB - The severity of the infarct-related residual coronary stenosis after spontaneous or therapeutic thrombolysis was quantitatively assessed in 91 patients with an acute myocardial infarction who were allocated to treatment in the acute stage with either a thrombolytic agent (100 mg of recombinant tissue-type plasminogen activator given over 3 h, 49 patients) or a placebo (42 patients). Heparin and aspirin were given to both groups until angiography was performed. Digital subtracted images of the infarct-related coronary vessel were obtained 10 to 14 days after hospital admission and were subsequently analyzed with the use of a computer-assisted coronary stenosis measurement system. Neither treatment group differed significantly in age, gender or location of the culprit coronary lesion. Median values (90% range) in the thrombolysis and control groups were, respectively, 1.95 (0.9 to 5.3) mm versus 1.7 (0.9 to 3.4) mm for stenosis length; 1.4 (0.8 to 2.7) mm versus 1.4 (0.9 to 1.8) mm for minimal luminal diameter; 57% (36% to 75%) versus 58% (44% to 71%) for diameter obstruction; 82% (59% to 95%) versus 82% (68% to 92%) for geometric area obstruction; and 78% (58% to 91%) versus 79% (66% to 90%) for densitometric area obstruction. The difference between the two groups was not statistically significant for any of these measurements. Thus, in this study no significant differences in anatomy or severity of residual coronary stenosis could be demonstrated at 10 to 14 days after an acute myocardial infarction in patients with a recanalized infarct-related vessel, whether or not thrombolytic therapy was given on admission. These results indicate that with effective antithrombotic treatment, gradual endogenous fibrinolysis or more rapid lysis induced by the infusion of a thrombolytic agent results in a similar infarct-related coronary lesion at the time of hospital discharge. RN - EC 3-4-21-68 (Tissue Plasminogen Activator) IS - 0735-1097 IL - 0735-1097 DI - 0735-1097(90)90298-4 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't ID - 2123904 [pubmed] ID - 0735-1097(90)90298-4 [pii] PP - ppublish LG - English DP - 1990 Dec DC - 19910124 EZ - 1990/12/01 00:00 DA - 1990/12/01 00:01 DT - 1990/12/01 YR - 1990 ED - 19910124 RD - 20161123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=2123904 <693. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 2384105 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Niemeyer MG AU - Laarman GJ AU - van der Wall EE AU - Cramer MJ AU - Verzijlbergen FJ AU - Zwinderman AH AU - Ascoop CA AU - Pauwels EK FA - Niemeyer, M G FA - Laarman, G J FA - van der Wall, E E FA - Cramer, M J FA - Verzijlbergen, F J FA - Zwinderman, A H FA - Ascoop, C A FA - Pauwels, E K IN - Niemeyer, M G. Department of Diagnostic Radiology, University Hospital, Leiden, The Netherlands. TI - Is quantitative analysis superior to visual analysis of planar thallium 201 myocardial exercise scintigraphy in the evaluation of coronary artery disease? Analysis of a prospective clinical study. SO - European Journal of Nuclear Medicine. 16(8-10):697-704, 1990 AS - Eur J Nucl Med. 16(8-10):697-704, 1990 NJ - European journal of nuclear medicine PI - Journal available in: Print PI - Citation processed from: Print JC - enc, 7606882 IO - Eur J Nucl Med SB - Index Medicus CP - Germany MH - *Coronary Disease/dg [Diagnostic Imaging] MH - Electrocardiography MH - Exercise Test MH - Female MH - *Heart/dg [Diagnostic Imaging] MH - Humans MH - *Image Processing, Computer-Assisted MH - Male MH - Middle Aged MH - Prospective Studies MH - Radionuclide Imaging MH - *Thallium Radioisotopes AB - Quantitative analysis of myocardial exercise scintigraphy has been previously reported to be superior to visual image interpretation for detection of the presence and extent of coronary artery disease. Computer analysis of perfusion defects and washout rate of thallium 201 was performed on scintigrams from a group of 131 consecutive patients (prospective group), using criteria defined from a previous group of 72 patients (initial group), and compared with visual interpretation of scintigrams for detection and evaluation of coronary artery disease. The sensitivity of the quantitative technique with regard to overall detection of coronary artery disease was not significantly different from the visual method (69% and 74%, respectively), whereas the specificity was higher (86% and 68%). Quantitative analysis did not increase the sensitivity of thallium imaging over the visual method in the left anterior descending artery (46% vs 65%) and the right coronary artery (51% vs 72%) but did increase sensitivity in the left circumflex artery (75% vs 47%). Whereas in the initial group quantitative analysis resulted in a better identification of multivessel disease (sensitivity 81% vs 57%), in the prospective group sensitivity decreased (54% vs 67%) without significant loss of specificity. The initial group had a 40% incidence of three-vessel disease and the prospective group, 22% (P less than 0.05). One-vessel disease was higher in the prospective group (32% vs 11%, P less than 0.05). Thus, assessing the quantitative technique in a larger prospective patient population, there was no improvement of detection of the presence and extent of coronary artery disease when compared with visual interpretation. RN - 0 (Thallium Radioisotopes) IS - 0340-6997 IL - 0340-6997 PT - Comparative Study PT - Journal Article ID - 2384105 [pubmed] PP - ppublish LG - English DP - 1990 DC - 19900920 EZ - 1990/01/01 00:00 DA - 1990/01/01 00:01 DT - 1990/01/01 YR - 1990 ED - 19900920 RD - 20161123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=2384105 <694. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 2721815 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tattersall AB AU - Ellis R FA - Tattersall, A B FA - Ellis, R IN - Tattersall, A B. Medical Department, Ciba-Geigy Pharmaceuticals, Horsham, UK. TI - The use of a hand-held computer to record clinical trial data in general practice: a pilot study. SO - Journal of International Medical Research. 17(2):185-9, 1989 Mar-Apr AS - J Int Med Res. 17(2):185-9, 1989 Mar-Apr NJ - The Journal of international medical research PI - Journal available in: Print PI - Citation processed from: Print JC - e62, 0346411 IO - J. Int. Med. Res. SB - Index Medicus CP - England MH - *Acetaminophen/tu [Therapeutic Use] MH - *Clinical Trials as Topic/mt [Methods] MH - *Dextropropoxyphene/tu [Therapeutic Use] MH - *Diclofenac/tu [Therapeutic Use] MH - Double-Blind Method MH - Drug Combinations/tu [Therapeutic Use] MH - Humans MH - *Joint Diseases/dt [Drug Therapy] MH - *Microcomputers MH - *Pain/dt [Drug Therapy] MH - Pilot Projects MH - Software AB - A system has been developed to collect and process clinical trial data in general practice using a hand-held computer in the patient's presence. It was based on a Psion Organiser II (model XP) computer using software produced for the trial. The major advantages are: (a) avoidance of protocol violations and other incorrect data entries; and (b) saving of time for investigators and company personnel. The present coding of symptoms was found to be the only major drawback, but this problem could be remedied for future studies. RN - 0 (Drug Combinations) RN - 144O8QL0L1 (Diclofenac) RN - 362O9ITL9D (Acetaminophen) RN - 39400-85-6 (acetaminophen, dextropropoxyphene, drug combination) RN - S2F83W92TK (Dextropropoxyphene) IS - 0300-0605 IL - 0300-0605 DO - https://dx.doi.org/10.1177/030006058901700212 PT - Comparative Study PT - Journal Article ID - 2721815 [pubmed] ID - 10.1177/030006058901700212 [doi] PP - ppublish LG - English DP - 1989 Mar-Apr DC - 19890710 EZ - 1989/03/01 00:00 DA - 1989/03/01 00:01 DT - 1989/03/01 YR - 1989 ED - 19890710 RD - 20170214 UP - 20170215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medc&AN=2721815 <695. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 2721815 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Tattersall AB AU - Ellis R FA - Tattersall, A B FA - Ellis, R IN - Tattersall, A B. Medical Department, Ciba-Geigy Pharmaceuticals, Horsham, UK. TI - The use of a hand-held computer to record clinical trial data in general practice: a pilot study. SO - Journal of International Medical Research. 17(2):185-9, 1989 Mar-Apr AS - J Int Med Res. 17(2):185-9, 1989 Mar-Apr NJ - The Journal of international medical research PI - Journal available in: Print PI - Citation processed from: Print JC - e62, 0346411 IO - J. Int. Med. Res. SB - Index Medicus CP - England MH - *Acetaminophen/tu [Therapeutic Use] MH - *Clinical Trials as Topic/mt [Methods] MH - *Dextropropoxyphene/tu [Therapeutic Use] MH - *Diclofenac/tu [Therapeutic Use] MH - Double-Blind Method MH - Drug Combinations/tu [Therapeutic Use] MH - Humans MH - *Joint Diseases/dt [Drug Therapy] MH - *Microcomputers MH - *Pain/dt [Drug Therapy] MH - Pilot Projects MH - Software AB - A system has been developed to collect and process clinical trial data in general practice using a hand-held computer in the patient's presence. It was based on a Psion Organiser II (model XP) computer using software produced for the trial. The major advantages are: (a) avoidance of protocol violations and other incorrect data entries; and (b) saving of time for investigators and company personnel. The present coding of symptoms was found to be the only major drawback, but this problem could be remedied for future studies. RN - 0 (Drug Combinations) RN - 144O8QL0L1 (Diclofenac) RN - 362O9ITL9D (Acetaminophen) RN - 39400-85-6 (acetaminophen, dextropropoxyphene, drug combination) RN - S2F83W92TK (Dextropropoxyphene) IS - 0300-0605 IL - 0300-0605 PT - Comparative Study PT - Journal Article ID - 2721815 [pubmed] PP - ppublish LG - English DP - 1989 Mar-Apr DC - 19890710 EZ - 1989/03/01 00:00 DA - 1989/03/01 00:01 DT - 1989/03/01 YR - 1989 ED - 19890710 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=2721815 <696. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 3408211 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Haskell WL AU - Fair J AU - Sanders W AU - Alderman EL FA - Haskell, W L FA - Fair, J FA - Sanders, W FA - Alderman, E L IN - Haskell, W L. Division of Cardiology, Stanford University, School of Medicine, CA. TI - New methodologies for studying the prevention of atherosclerosis. SO - Annals of Clinical Research. 20(1-2):39-45, 1988 AS - Ann Clin Res. 20(1-2):39-45, 1988 NJ - Annals of clinical research PI - Journal available in: Print PI - Citation processed from: Print JC - 53a, 0220042 IO - Ann. Clin. Res. SB - Index Medicus CP - Finland MH - Coronary Angiography MH - Coronary Artery Disease/dg [Diagnostic Imaging] MH - *Coronary Artery Disease/pc [Prevention & Control] MH - Humans MH - Random Allocation MH - Risk Factors AB - To determine if multiple risk factor modification favorably alters the rate of progression of coronary atherosclerosis, 300 patients with established atherosclerosis have been randomized into a clinical trial; 155 to usual care and 145 to special intervention. All patients have medical/risk examinations at baseline and annually for 4 years. The special intervention patients undergo aggressive risk factor management with emphasis on lipoprotein modification, dietary management, smoking abatement, blood pressure control, weight loss and increased physical activity. To measure progression of atherosclerosis, a quantitative, computer-assisted coronary arteriographic system was developed to analyze the baseline and 4-year follow-up arteriograms. This procedure uses a catheter with a metallic calibration cylinder at its tip to determine absolute artery size and automated computer edge detection techniques to define the internal border of the artery. The analysis system detects artery borders using changes in cine film density and measures distances between these borders. For each segment the minimum, maximum and mean diameters are measured and percent stenosis and atheroma area calculated. This system provides precise and reproducible measures of coronary artery segment diameter. Using this technique, we estimate a 33% reduction in the rate of coronary artery progression over 4 years, defined as mean segment diameter, can be detected at a power of 0.80 and an alpha of 0.05 (one tailed test) with a sample size of 120 in each of 2 groups. IS - 0003-4762 IL - 0003-4762 PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial ID - 3408211 [pubmed] PP - ppublish LG - English DP - 1988 DC - 19880922 EZ - 1988/01/01 00:00 DA - 1988/01/01 00:01 DT - 1988/01/01 YR - 1988 ED - 19880922 RD - 20161123 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=3408211 <697. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 3534177 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - McDonald CJ AU - Tierney WM FA - McDonald, C J FA - Tierney, W M TI - Research uses of computer-stored practice records in general medicine. SO - Journal of General Internal Medicine. 1(4 Suppl):S19-24, 1986 Jul-Aug AS - J Gen Intern Med. 1(4 Suppl):S19-24, 1986 Jul-Aug NJ - Journal of general internal medicine PI - Journal available in: Print PI - Citation processed from: Print JC - jgi, 8605834 IO - J Gen Intern Med SB - Index Medicus CP - United States MH - Clinical Trials as Topic MH - *Family Practice MH - *Medical Informatics MH - *Medical Records MH - *Practice Management, Medical MH - Random Allocation MH - Research IS - 0884-8734 IL - 0884-8734 PT - Clinical Trial PT - Journal Article ID - 3534177 [pubmed] PP - ppublish LG - English DP - 1986 Jul-Aug DC - 19861216 EZ - 1986/07/01 00:00 DA - 1986/07/01 00:01 DT - 1986/07/01 YR - 1986 ED - 19861216 RD - 20090224 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med2&AN=3534177 <698. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 3094664 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Adams ID AU - Chan M AU - Clifford PC AU - Cooke WM AU - Dallos V AU - de Dombal FT AU - Edwards MH AU - Hancock DM AU - Hewett DJ AU - McIntyre N AU - et al FA - Adams, I D FA - Chan, M FA - Clifford, P C FA - Cooke, W M FA - Dallos, V FA - de Dombal, F T FA - Edwards, M H FA - Hancock, D M FA - Hewett, D J FA - McIntyre, N TI - Computer aided diagnosis of acute abdominal pain: a multicentre study. SO - British Medical Journal Clinical Research Ed.. 293(6550):800-4, 1986 Sep 27 AS - Br Med J (Clin Res Ed). 293(6550):800-4, 1986 Sep 27 NJ - British medical journal (Clinical research ed.) PI - Journal available in: Print PI - Citation processed from: Print JC - b4x, 8302911 IO - Br Med J (Clin Res Ed) PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1341582 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - *Abdomen MH - Appendicitis/di [Diagnosis] MH - Clinical Trials as Topic MH - *Diagnosis, Computer-Assisted MH - Diagnostic Errors MH - England MH - Hospitalization/ec [Economics] MH - Humans MH - *Pain/di [Diagnosis] MH - Pain/et [Etiology] MH - Technology Assessment, Biomedical AB - A multicentre study of computer aided diagnosis for patients with acute abdominal pain was performed in eight centres with over 250 participating doctors and 16,737 patients. Performance in diagnosis and decision making was compared over two periods: a test period (when a small computer system was provided to aid diagnosis) and a baseline period (before the system was installed). The two periods were well matched for type of case and rate of accrual. The system proved reliable and was used in 75.1% of possible cases. User reaction was broadly favourable. During the test period improvements were noted in diagnosis, decision making, and patient outcome. Initial diagnostic accuracy rose from 45.6% to 65.3%. The negative laparotomy rate fell by almost half, as did the perforation rate among patients with appendicitis (from 23.7% to 11.5%). The bad management error rate fell from 0.9% to 0.2%, and the observed mortality fell by 22.0%. The savings made were estimated as amounting to 278 laparotomies and 8,516 bed nights during the trial period--equivalent throughout the National Health Service to annual savings in resources worth over 20m pounds and direct cost savings of over 5m pounds. Computer aided diagnosis is a useful system for improving diagnosis and encouraging better clinical practice. IS - 0267-0623 IL - 0267-0623 PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't ID - 3094664 [pubmed] ID - PMC1341582 [pmc] PP - ppublish LG - English DP - 1986 Sep 27 DC - 19861204 EZ - 1986/09/27 00:00 DA - 1986/09/27 00:01 DT - 1986/09/27 YR - 1986 ED - 19861204 RD - 20131001 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med2&AN=3094664 <699. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 6395756 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Morganroth J FA - Morganroth, J TI - Computer recognition of cardiac arrhythmias and statistical approaches to arrhythmia analysis. SO - Annals of the New York Academy of Sciences. 432:117-28, 1984 AS - Ann N Y Acad Sci. 432:117-28, 1984 NJ - Annals of the New York Academy of Sciences PI - Journal available in: Print PI - Citation processed from: Print JC - 5nm, 7506858 IO - Ann. N. Y. Acad. Sci. SB - Index Medicus CP - United States MH - Analysis of Variance MH - Anti-Arrhythmia Agents/tu [Therapeutic Use] MH - Arrhythmias, Cardiac/di [Diagnosis] MH - *Arrhythmias, Cardiac/dt [Drug Therapy] MH - Clinical Trials as Topic MH - Computers MH - Electrocardiography/is [Instrumentation] MH - *Electrocardiography MH - Humans MH - Monitoring, Physiologic/is [Instrumentation] AB - The recognition of marked spontaneous variability in the frequency of ventricular ectopy has required the analysis of various statistical approaches to define appropriate guidelines for determining that a therapeutic agent, rather than spontaneous variability alone, is the cause of an observed reduction in VPC frequency. Analysis of variance or linear regression techniques have been applied to ambulatory ECG data obtained on different patient population groups. When similar patient groups are studied with comparable assumptions, then either of these statistical techniques provides similar guidelines to detect spontaneous variation as the cause of ventricular ectopic reduction. A 75% minimal reduction in VPC frequency should be required when comparing one 24-hour ambulatory monitoring period with another. The impact of spontaneous variability of ventricular ectopy on clinical trial designs is discussed, as is the categorization of various ambulatory ECG monitoring recorders and analysis systems. RN - 0 (Anti-Arrhythmia Agents) IS - 0077-8923 IL - 0077-8923 PT - Clinical Trial PT - Journal Article ID - 6395756 [pubmed] PP - ppublish LG - English DP - 1984 DC - 19850228 EZ - 1984/01/01 00:00 DA - 1984/01/01 00:01 DT - 1984/01/01 YR - 1984 ED - 19850228 RD - 20071115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med2&AN=6395756 <700. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 6389645 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Myers J AU - Ahnve S AU - Froelicher V AU - Livingston M AU - Jensen D AU - Abramson I AU - Sullivan M AU - Mortara D FA - Myers, J FA - Ahnve, S FA - Froelicher, V FA - Livingston, M FA - Jensen, D FA - Abramson, I FA - Sullivan, M FA - Mortara, D TI - A randomized trail of the effects of 1 year of exercise training on computer-measured ST segment displacement in patients with coronary artery disease. SO - Journal of the American College of Cardiology. 4(6):1094-102, 1984 Dec AS - J Am Coll Cardiol. 4(6):1094-102, 1984 Dec NJ - Journal of the American College of Cardiology PI - Journal available in: Print PI - Citation processed from: Print JC - h50, 8301365 IO - J. Am. Coll. Cardiol. SB - Index Medicus CP - United States MH - Adult MH - Aged MH - Clinical Trials as Topic MH - Coronary Disease/pp [Physiopathology] MH - *Coronary Disease/rh [Rehabilitation] MH - Electrocardiography MH - Exercise Test MH - *Exercise Therapy MH - Heart Rate MH - Humans MH - Male MH - Middle Aged MH - Myocardium/me [Metabolism] MH - Oxygen Consumption MH - Physical Education and Training MH - Physical Exertion MH - Random Allocation MH - Time Factors AB - As part of a randomized trial of the effects of 1 year of exercise training on patients with stable coronary artery disease, 48 patients who exercised and 59 control patients had computerized exercise electrocardiography performed initially and 1 year later. The patients who had exercise training as an intervention had a 9% increase in measured maximal oxygen consumption and significant decreases in heart rate at rest and during submaximal exercise. ST segment displacement was analyzed 60 ms after the end of the QRS complex in the three-dimensional X, Y and Z leads and utilizing the spatial amplitude derived from them. Statistical analysis by t testing yielded no significant differences between the groups except for less ST segment displacement at a matched work load, but this could be explained by a lowered heart rate. Analysis of variance yielded some minor differences within clinical subgroups, particularly in the spatial analysis. Obvious changes in exercise-induced ST segment depression could not be demonstrated in this heterogeneous group of selected volunteers with coronary artery disease secondary to an exercise program. IS - 0735-1097 IL - 0735-1097 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. ID - 6389645 [pubmed] PP - ppublish GI - No: 1 F05 TW03308-01 Organization: (TW) *FIC NIH HHS* Country: United States No: HL17682 Organization: (HL) *NHLBI NIH HHS* Country: United States LG - English DP - 1984 Dec DC - 19841227 EZ - 1984/12/01 00:00 DA - 1984/12/01 00:01 DT - 1984/12/01 YR - 1984 ED - 19841227 RD - 20081121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med2&AN=6389645 <701. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 7261636 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Karrison T FA - Karrison, T TI - Data editing in a clinical trial. SO - Controlled Clinical Trials. 2(1):15-29, 1981 May AS - Control Clin Trials. 2(1):15-29, 1981 May NJ - Controlled clinical trials PI - Journal available in: Print PI - Citation processed from: Print JC - dsl, 8006242 IO - Control Clin Trials SB - Index Medicus CP - United States MH - *Clinical Trials as Topic MH - *Computers MH - Data Collection MH - *Filing MH - *Forms and Records Control/mt [Methods] MH - Medical Records MH - *Office Management/mt [Methods] MH - Quality Control AB - In clinical research and, particularly, in multicenter clinical trials, data are collected onto study forms designed to minimize errors in the recorded data. Nevertheless, errors of various kinds must be anticipated, and it is necessary to devise means to detect, review, and correct erroneous values. General requirements of a data editing system and methods for accomplishing these tasks are presented. A general computer program for error detection and a method for updating the data base that leaves an "audit trail" of the original data and subsequent corrections are described. IS - 0197-2456 IL - 0197-2456 PT - Journal Article ID - 7261636 [pubmed] PP - ppublish LG - English DP - 1981 May DC - 19811025 EZ - 1981/05/01 00:00 DA - 1981/05/01 00:01 DT - 1981/05/01 YR - 1981 ED - 19811025 RD - 20071115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med2&AN=7261636 <702. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 7191298 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Reiterer W FA - Reiterer, W TI - Effects of different preparations of oxprenolol on diurnal variations of non-steady-state exercise performance in patients with coronary heart disease evaluated by computer assisted ergospirometry. SO - Arzneimittel-Forschung. 30(7):1147-53, 1980 AS - Arzneimittelforschung. 30(7):1147-53, 1980 NJ - Arzneimittel-Forschung PI - Journal available in: Print PI - Citation processed from: Print JC - 91u, 0372660 IO - Arzneimittelforschung OI - Source: NASA. 81021364 SB - Index Medicus SB - National Aeronautics and Space Administration (NASA) Journals CP - Germany MH - Adult MH - Biological Availability MH - Circadian Rhythm MH - *Coronary Disease/pp [Physiopathology] MH - Heart Rate/de [Drug Effects] MH - Humans MH - Male MH - Middle Aged MH - Oxprenolol/ad [Administration & Dosage] MH - Oxprenolol/me [Metabolism] MH - *Oxprenolol/pd [Pharmacology] MH - Oxygen Consumption/de [Drug Effects] MH - *Physical Exertion MH - Respiration/de [Drug Effects] MH - Spirometry/mt [Methods] AB - The effect of two preparations of oxprenolol (80 mg twice a day; 160 mg slow-release once a day) on the diurnal non-steady-state exercise performance in patients with coronary heart disease (N = 11) has been studied after a treatment period of at least 7 days. 2 h after the intake of the standard preparation (80 mg oxprenolol) the symptom-limited exercise performance increased by 24%. The onset of symptoms of physical intolerance was postponed to work rates of heavier intensity (+18.8%). Despite a considerable fall in the exercise heart rate (-18.4%) the oxygen uptake per load was not affected suggesting that the adjustment of the cardio-pulmonary system to graded exercise was not impaired. As the reduction of the exercise heart rate is regarded as a distinct sign of beta-receptor blockade the standard regimen demonstrates a considerable long-term effect with respect to the heart rate regulation next morning (time interval 16 h). The slow-release preparation acts less powerfully in reducing the exercise heart rate in any test, but the beneficial effects on limiting symptoms of physical performance equal the standard regimen. The duration of the efficacy of slow-release oxprenolol is certainly limited: no effect on the exercise heart rate was demonstrable next morning (time interval 25 h). To improve the efficacy in symptomatic treatment of coronary heart disease the duration of effects of the drug and the physical activities of the individual during every day life should be taken into account to adjust the timing for intake. RN - 519MXN9YZR (Oxprenolol) IS - 0004-4172 IL - 0004-4172 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 7191298 [pubmed] PP - ppublish LG - English DP - 1980 DC - 19801120 EZ - 1980/01/01 00:00 DA - 1980/01/01 00:01 DT - 1980/01/01 YR - 1980 ED - 19801120 RD - 20131121 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med2&AN=7191298 <703. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 588914 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Husband JE AU - Meire HB AU - Kreel L FA - Husband, J E FA - Meire, H B FA - Kreel, L TI - Comparison of ultrasound and computer-assisted tomography in pancreatic diagnosis. SO - British Journal of Radiology. 50(600):855-62, 1977 Dec AS - Br J Radiol. 50(600):855-62, 1977 Dec NJ - The British journal of radiology PI - Journal available in: Print PI - Citation processed from: Print JC - b28, 0373125 IO - Br J Radiol SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - Carcinoma/di [Diagnosis] MH - Humans MH - Lymphoma/di [Diagnosis] MH - *Pancreatic Diseases/di [Diagnosis] MH - Pancreatic Neoplasms/di [Diagnosis] MH - Pancreatitis/di [Diagnosis] MH - *Tomography, X-Ray Computed MH - *Ultrasonography AB - In a series of patients suspected of having pancreatic disease both ultrasound and computerized tomography (CT) were performed. The diagnosis has been confirmed in 50 patients. Computerized tomography visualized the pancreas in all 50 (100%) whereas ultrasound was successful in 40 patients (80%). The ultrasound failures were due to bowel gas anterior to the pancreas. The overall diagnostic accuracy was 84% for computerized tomography and 64% for ultrasound; however, in those cases where ultrasound successfully detected the pancreas the diagnostic accuracy was 80%. IS - 0007-1285 IL - 0007-1285 DO - https://dx.doi.org/10.1259/0007-1285-50-600-855 PT - Clinical Trial PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article ID - 588914 [pubmed] ID - 10.1259/0007-1285-50-600-855 [doi] PP - ppublish LG - English DP - 1977 Dec DC - 19780223 EZ - 1977/12/01 00:00 DA - 1977/12/01 00:01 DT - 1977/12/01 YR - 1977 ED - 19780223 RD - 20061115 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med1&AN=588914 <704. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 48773 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Vetter NJ AU - Julian DG FA - Vetter, N J FA - Julian, D G TI - Comparison of arrhythmia computer and conventional monitoring in coronary-care unit. SO - Lancet. 1(7917):1151-4, 1975 May 24 AS - Lancet. 1(7917):1151-4, 1975 May 24 NJ - Lancet (London, England) PI - Journal available in: Print PI - Citation processed from: Print JC - 2985213r, l0s, 0053266 IO - Lancet SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - Adult MH - Aged MH - *Arrhythmias, Cardiac/di [Diagnosis] MH - Arrhythmias, Cardiac/ep [Epidemiology] MH - Arrhythmias, Cardiac/th [Therapy] MH - *Computers MH - Computers, Analog MH - Computers, Hybrid MH - *Coronary Care Units MH - Evaluation Studies as Topic MH - False Positive Reactions MH - Female MH - Humans MH - Male MH - Methods MH - Middle Aged MH - *Monitoring, Physiologic/is [Instrumentation] MH - Online Systems MH - Tape Recording MH - Time Factors AB - Conventional methods of monitoring arrhythmias impose heavy demands on staff and are unreliable. On-line arrhythmia computers have been developed to overcome these problems, but there has been no critical evaluation of the functioning of such a system in a clinical setting. A comparison was made of the efficacy of two methods of monitoring in detecting arrhythmias in sixty-four patients in a coronary-care unit. Half the patients were monitored by a commercially available arrhythmia computer; the other half were monitored by conventional means with a rate-triggered alarm system. More than 99 percent of episodes of potentially serious ventricular arrhythmias were detected by the computer; 95 percent of patients with these arrhythmias were treated immediately. In those monitored by conventional means, a large proporation of such arrhythmias were unrecognised: only 17 percent of affected patients received immediate antiarrhythmic therapy. In 30 percent, treatment was delayed for several hours, and none was given in 52 percent. False alarms occurred with both systems but were more readily recognised as such in the computer-monitored patients. It is concluded that an arrhythmia computer improves the standards of arrhythmia detection, leads to quicker institution of treatment, and diminishes the demand on skilled staff. IS - 0140-6736 IL - 0140-6736 DI - S0140-6736(75)93134-7 PT - Clinical Trial PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article ID - 48773 [pubmed] ID - S0140-6736(75)93134-7 [pii] PP - ppublish LG - English DP - 1975 May 24 DC - 19750829 EZ - 1975/05/24 00:00 DA - 1975/05/24 00:01 DT - 1975/05/24 YR - 1975 ED - 19750829 RD - 20150616 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med1&AN=48773 <705. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 1093613 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Wilson PD AU - Horrocks JC AU - Lyndon PJ AU - Yeung CK AU - Page RE AU - De Dombal FT FA - Wilson, P D FA - Horrocks, J C FA - Lyndon, P J FA - Yeung, C K FA - Page, R E FA - De Dombal, F T TI - Simplified computer-aided diagnosis of acute abdominal pain. SO - British Medical Journal. 2(5962):73-5, 1975 Apr 12 AS - Br Med J. 2(5962):73-5, 1975 Apr 12 NJ - British medical journal PI - Journal available in: Print PI - Citation processed from: Print JC - b4w, 0372673 IO - Br Med J PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1673059 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - *Abdomen, Acute/di [Diagnosis] MH - *Diagnosis, Computer-Assisted MH - Diagnostic Errors MH - Education MH - Feedback MH - Humans AB - A simplified version of a system for computer-aided diagnosis of acute abdominal pain has been tested by "new" personnel unfamiliar with the previous system. After a two-month learning period the system proved more accurate in its diagnoses than the unaided clinician, and during the first five months of using the system the unaided clinicians' accuracy rose from 73% to 84%. When computer "feedback" was withdrawn the clinicians' diagnostic accuracy reverted towards the previous, "unaided" level. These findings further validate the concept of the computer as a potentially valuable diagnostic aid but indicate that a training period and computer feedback are important factors in its 4 use. IS - 0007-1447 IL - 0007-1447 PT - Clinical Trial PT - Controlled Clinical Trial PT - Journal Article ID - 1093613 [pubmed] ID - PMC1673059 [pmc] PP - ppublish LG - English DP - 1975 Apr 12 DC - 19750822 EZ - 1975/04/12 00:00 DA - 1975/04/12 00:01 DT - 1975/04/12 YR - 1975 ED - 19750822 RD - 20091118 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med1&AN=1093613 <706. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 4594585 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - De Dombal FT AU - Leaper DJ AU - Horrocks JC AU - Staniland JR AU - McCann AP FA - De Dombal, F T FA - Leaper, D J FA - Horrocks, J C FA - Staniland, J R FA - McCann, A P TI - Human and computer-aided diagnosis of abdominal pain: further report with emphasis on performance of clinicians. SO - British Medical Journal. 1(5904):376-80, 1974 Mar 02 AS - Br Med J. 1(5904):376-80, 1974 Mar 02 NJ - British medical journal PI - Journal available in: Print PI - Citation processed from: Print JC - b4w, 0372673 IO - Br Med J PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1633627 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - *Abdomen MH - Abdomen, Acute/di [Diagnosis] MH - Appendicitis/di [Diagnosis] MH - Cholecystitis/di [Diagnosis] MH - *Diagnosis, Computer-Assisted MH - Diagnosis, Differential MH - Diverticulitis/di [Diagnosis] MH - Duodenal Ulcer/di [Diagnosis] MH - Humans MH - Intestinal Obstruction/di [Diagnosis] MH - *Pain/di [Diagnosis] MH - Pancreatitis/di [Diagnosis] AB - This paper reports a controlled trial of human and computer-aided diagnosis in a series of 552 patients with acute abdominal pain. The overall diagnostic accuracy of the computer-aided system was 91.5% and that of the senior clinician to see each case was 81.2%. However, the clinician's diagnostic performance improved markedly during the period of the trial. The proportion of appendices which perforated before operation fell from 36% to 4% during the trial, and the negative laparotomy rate dropped sharply. After the trial closed in August 1972 these figures reverted towards their pretrial levels.It is suggested that while computer-aided diagnosis is a valuable direct adjunct to the clinician dealing with the "acute abdomen," he may also benefit in the short-term from the constant feedback he receives and from the disciplines and constraints involved in communicating with the computer. IS - 0007-1447 IL - 0007-1447 PT - Clinical Trial PT - Controlled Clinical Trial PT - Journal Article ID - 4594585 [pubmed] ID - PMC1633627 [pmc] PP - ppublish LG - English DP - 1974 Mar 02 DC - 19740529 EZ - 1974/03/02 00:00 DA - 1974/03/02 00:01 DT - 1974/03/02 YR - 1974 ED - 19740529 RD - 20101026 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med1&AN=4594585 <707. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 4542728 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - Morgan A AU - Anderson W AU - Bevilacqua R AU - Cohn L AU - Moore FD AU - Collins JJ Jr FA - Morgan, A FA - Anderson, W FA - Bevilacqua, R FA - Cohn, L FA - Moore, F D FA - Collins, J J Jr TI - Effects of computer-controlled transfusion on recovery from cardiac surgery. SO - Annals of Surgery. 178(4):391-8, 1973 Oct AS - Ann Surg. 178(4):391-8, 1973 Oct NJ - Annals of surgery PI - Journal available in: Print PI - Citation processed from: Print JC - 67s, 0372354 IO - Ann. Surg. PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1355667 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States MH - *Blood Transfusion MH - *Computers MH - *Coronary Artery Bypass MH - Evaluation Studies as Topic MH - Female MH - *Heart Valve Prosthesis MH - *Heart Valves/su [Surgery] MH - Hemodynamics MH - Humans MH - Length of Stay MH - Male MH - Middle Aged MH - Postoperative Care MH - Postoperative Complications IS - 0003-4932 IL - 0003-4932 PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial ID - 4542728 [pubmed] ID - PMC1355667 [pmc] PP - ppublish LG - English DP - 1973 Oct DC - 19731214 EZ - 1973/10/01 00:00 DA - 2001/03/28 10:01 DT - 1973/10/01 YR - 1973 ED - 19731214 RD - 20130926 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med1&AN=4542728 <708. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 4552594 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - MEDLINE AU - de Dombal FT AU - Leaper DJ AU - Staniland JR AU - McCann AP AU - Horrocks JC FA - de Dombal, F T FA - Leaper, D J FA - Staniland, J R FA - McCann, A P FA - Horrocks, J C TI - Computer-aided diagnosis of acute abdominal pain. SO - British Medical Journal. 2(5804):9-13, 1972 Apr 01 AS - Br Med J. 2(5804):9-13, 1972 Apr 01 NJ - British medical journal PI - Journal available in: Print PI - Citation processed from: Print JC - b4w, 0372673 IO - Br Med J PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1789017 SB - Core Clinical Journals (AIM) SB - Index Medicus CP - England MH - *Abdomen, Acute/di [Diagnosis] MH - Abdomen, Acute/et [Etiology] MH - Abdomen, Acute/su [Surgery] MH - Appendicitis/di [Diagnosis] MH - Cholecystitis/di [Diagnosis] MH - *Computers MH - Diagnosis, Computer-Assisted MH - Diagnosis, Differential MH - Diverticulitis/di [Diagnosis] MH - Humans MH - Intestinal Obstruction/di [Diagnosis] MH - Intestine, Small MH - Methods MH - Pancreatitis/di [Diagnosis] MH - Peptic Ulcer Perforation/di [Diagnosis] AB - This paper reports a controlled prospective unselected real-time comparison of human and computer-aided diagnosis in a series of 304 patients suffering from abdominal pain of acute onset.The computing system's overall diagnostic accuracy (91.8%) was significantly higher than that of the most senior member of the clinical team to see each case (79.6%). It is suggested as a result of these studies that the provision of such a system to aid the clinician is both feasible in a real-time clinical setting, and likely to be of practical value, albeit in a small percentage of cases. IS - 0007-1447 IL - 0007-1447 PT - Clinical Trial PT - Controlled Clinical Trial PT - Journal Article ID - 4552594 [pubmed] ID - PMC1789017 [pmc] PP - ppublish LG - English DP - 1972 Apr 01 DC - 19720611 EZ - 1972/04/01 00:00 DA - 1972/04/01 00:01 DT - 1972/04/01 YR - 1972 ED - 19720611 RD - 20130926 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med1&AN=4552594 <709. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27923167 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Process AU - Tsafrir Z AU - Palmer M AU - Dahlman M AU - Nawfal AK AU - Aoun J AU - Taylor A AU - Fisher J AU - Theoharis E AU - Eisenstein D FA - Tsafrir, Ziv FA - Palmer, Matthew FA - Dahlman, Marisa FA - Nawfal, A Karim FA - Aoun, Joelle FA - Taylor, Andrew FA - Fisher, Jay FA - Theoharis, Evan FA - Eisenstein, David IN - Tsafrir, Ziv. Division of Minimally Invasive Gynecology, Department of Obstetrics and Gynecology, Henry Ford Health System, 2799 W. Grand Blvd, Detroit, MI 48202, USA; The Department of Gynecology, Lis Maternity Hospital, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel- Aviv, Israel. Electronic address: zivtsafrir@gmail.com. IN - Palmer, Matthew. Division of Minimally Invasive Gynecology, Department of Obstetrics and Gynecology, Henry Ford Health System, 2799 W. Grand Blvd, Detroit, MI 48202, USA. IN - Dahlman, Marisa. Division of Minimally Invasive Gynecology, Department of Obstetrics and Gynecology, Henry Ford Health System, 2799 W. Grand Blvd, Detroit, MI 48202, USA. IN - Nawfal, A Karim. Division of Minimally Invasive Gynecology, Department of Obstetrics and Gynecology, Henry Ford Health System, 2799 W. Grand Blvd, Detroit, MI 48202, USA. IN - Aoun, Joelle. Division of Minimally Invasive Gynecology, Department of Obstetrics and Gynecology, Henry Ford Health System, 2799 W. Grand Blvd, Detroit, MI 48202, USA. IN - Taylor, Andrew. Division of Biostatistics, Public Health Sciences, Henry Ford Health System, Detroit, MI, USA. IN - Fisher, Jay. Division of Minimally Invasive Gynecology, Department of Obstetrics and Gynecology, Henry Ford Health System, 2799 W. Grand Blvd, Detroit, MI 48202, USA. IN - Theoharis, Evan. Division of Minimally Invasive Gynecology, Department of Obstetrics and Gynecology, Henry Ford Health System, 2799 W. Grand Blvd, Detroit, MI 48202, USA. IN - Eisenstein, David. Division of Minimally Invasive Gynecology, Department of Obstetrics and Gynecology, Henry Ford Health System, 2799 W. Grand Blvd, Detroit, MI 48202, USA. TI - Long-term outcomes for different vaginal cuff closure techniques in robotic-assisted laparoscopic hysterectomy: A randomized controlled trial. SO - European Journal of Obstetrics, Gynecology, & Reproductive Biology. 210:7-12, 2017 Mar AS - Eur J Obstet Gynecol Reprod Biol. 210:7-12, 2017 Mar NJ - European journal of obstetrics, gynecology, and reproductive biology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - e4l, 0375672 IO - Eur. J. Obstet. Gynecol. Reprod. Biol. CP - Ireland KW - Barbed suture; Braided suture; Robotic hysterectomy; Vaginal closure techniques; Vaginal cuff dehiscence AB - OBJECTIVE: This randomized controlled trial aimed to evaluate the outcomes of different vaginal cuff closure techniques in robotic-assisted total laparoscopic hysterectomy. AB - STUDY DESIGN: Ninety women undergoing robotic-assisted total laparoscopic hysterectomy for benign disease were randomized to three vaginal cuff closure techniques: running 2.0 V-LockTM (Arm 1), 0 VicrylTM figure-of-eight (Arm 2), and running 0 VicrylTM with Lapra-Ty (Arm 3). Patients' records were reviewed for age, body mass index, smoking status and relevant co-morbidities. Operative times for vaginal closure and total length of surgery, estimated blood loss, and peri-operative complications were collected. Patients were evaluated at 2 and 6 weeks post-operatively, and interviewed 1year following surgery by a telephone survey. Outcomes evaluated were vaginal cuff dehiscence, pain, dyspareunia and bleeding. AB - RESULTS: The study arms did not differ with respect to estimated blood loss (50mL in each arm; p=0.34), median vaginal cuff closure time (14.5, 12 and 13min, respectively; p=0.09) or readmission (p=0.55). In the 1-year follow-up (54/90 respondents; 60%), there were no significant differences among study arms for vaginal bleeding, cuff infection or dyspareunia. Only women belonging to arm 3 reported vaginal pain (0%, 0% and 23%, respectively; p=0.01). No cases of vaginal cuff dehiscence were observed. AB - CONCLUSIONS: The type of closure technique has no significant impact on patient outcomes. In the absence of a clear advantage of one technique over the others, the decision regarding the preferred method to close the vaginal cuff in robotic-assisted total laparoscopic hysterectomy should be based on surgeons' preference and cost effectiveness. AB - Copyright © 2016. Published by Elsevier B.V. ES - 1872-7654 IL - 0301-2115 DI - S0301-2115(16)31030-2 DO - https://dx.doi.org/10.1016/j.ejogrb.2016.11.018 PT - Journal Article ID - S0301-2115(16)31030-2 [pii] ID - 10.1016/j.ejogrb.2016.11.018 [doi] PP - ppublish PH - 2016/06/08 [received] PH - 2016/10/14 [revised] PH - 2016/11/15 [accepted] LG - English EP - 20161116 DP - 2017 Mar DC - 20161206 EZ - 2016/12/07 06:00 DA - 2016/12/07 06:00 DT - 2016/12/07 06:00 YR - 2017 RD - 20170430 UP - 20170502 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27923167 <710. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28186429 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Process AU - Daskalaki D AU - Gonzalez-Heredia R AU - Brown M AU - Bianco FM AU - Tzvetanov I AU - Davis M AU - Kim J AU - Benedetti E AU - Giulianotti PC FA - Daskalaki, Despoina FA - Gonzalez-Heredia, Raquel FA - Brown, Marc FA - Bianco, Francesco M FA - Tzvetanov, Ivo FA - Davis, Myriam FA - Kim, Jihun FA - Benedetti, Enrico FA - Giulianotti, Pier C IN - Daskalaki, Despoina. 1 Division of General, Minimally Invasive, and Robotic Surgery, Department of Surgery, University of Illinois at Chicago , Chicago, Illinois. IN - Gonzalez-Heredia, Raquel. 1 Division of General, Minimally Invasive, and Robotic Surgery, Department of Surgery, University of Illinois at Chicago , Chicago, Illinois. IN - Brown, Marc. 2 AlixPartners, Chicago, Illinois. IN - Bianco, Francesco M. 1 Division of General, Minimally Invasive, and Robotic Surgery, Department of Surgery, University of Illinois at Chicago , Chicago, Illinois. IN - Tzvetanov, Ivo. 3 Division of Transplantation, Department of Surgery, University of Illinois at Chicago , Chicago, Illinois. IN - Davis, Myriam. 1 Division of General, Minimally Invasive, and Robotic Surgery, Department of Surgery, University of Illinois at Chicago , Chicago, Illinois. IN - Kim, Jihun. 1 Division of General, Minimally Invasive, and Robotic Surgery, Department of Surgery, University of Illinois at Chicago , Chicago, Illinois. IN - Benedetti, Enrico. 3 Division of Transplantation, Department of Surgery, University of Illinois at Chicago , Chicago, Illinois. IN - Giulianotti, Pier C. 1 Division of General, Minimally Invasive, and Robotic Surgery, Department of Surgery, University of Illinois at Chicago , Chicago, Illinois. TI - Financial Impact of the Robotic Approach in Liver Surgery: A Comparative Study of Clinical Outcomes and Costs Between the Robotic and Open Technique in a Single Institution. SO - Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A. 27(4):375-382, 2017 Apr AS - J Laparoendosc Adv Surg Tech A. 27(4):375-382, 2017 Apr NJ - Journal of laparoendoscopic & advanced surgical techniques. Part A PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 9706293, c0d IO - J Laparoendosc Adv Surg Tech A CP - United States KW - cost; liver surgery; robotic surgery AB - BACKGROUND: One of the perceived major drawbacks of minimally invasive techniques has always been its cost. This is especially true for the robotic approach and is one of the main reasons that has prevented its wider acceptance among hospitals and surgeons. The aim of our study was to evaluate the clinical outcomes and economic impact of robotic and open liver surgery in a single institution. AB - METHODS: Sixty-eight robotic and 55 open hepatectomies were performed at our institution between January 1, 2009 and December 31, 2013. Demographics, perioperative data, and postoperative outcomes were collected and compared between the two groups. An independent company performed the financial analysis. The economic parameters comprised direct variable costs, direct fixed costs, and indirect costs. AB - RESULTS: Mean estimated blood loss was significantly less in the robotic group (438 versus 727.8mL; P=.038). Overall morbidity was significantly lower in the robotic group (22% versus 40%; P=.047). Clavien III/IV complications were also lower, with 4.4% in the robotic versus 16.3% in the open group (P=.043). The length of stay in the intensive care unit (ICU) was shorter for patients who underwent a robotic procedure (2.1 versus 3.3 days; P=.004). The average total cost, including readmissions, was $37,518 for robotic surgery and $41,948 for open technique. AB - CONCLUSIONS: Robotic liver resections had less overall morbidity, ICU, and hospital stay. This translates into decreased average costs for robotic surgery. These procedures are financially comparable to open resections and do not represent a financial burden to the hospital. ES - 1557-9034 IL - 1092-6429 DO - https://dx.doi.org/10.1089/lap.2016.0576 PT - Journal Article ID - 10.1089/lap.2016.0576 [doi] ID - PMC5397272 [pmc] PP - ppublish LG - English EP - 20170210 DP - 2017 Apr DC - 20170210 EZ - 2017/02/11 06:00 DA - 2017/02/12 06:00 DT - 2017/02/12 06:00 YR - 2017 RD - 20170428 UP - 20170501 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=28186429 <711. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28188953 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Process AU - Morisod B AU - Venara-Vulpe II AU - Alzuphar S AU - Monnier Y AU - Bongiovanni M AU - Hagmann P AU - Bouchaab H AU - Bourhis J AU - Simon C FA - Morisod, Benoit FA - Venara-Vulpe, Ioana I FA - Alzuphar, Stephen FA - Monnier, Yan FA - Bongiovanni, Massimo FA - Hagmann, Patric FA - Bouchaab, Hanan FA - Bourhis, Jean FA - Simon, Christian IN - Morisod, Benoit. Department of Otolaryngology - Head and Neck Surgery, CHUV, University of Lausanne, Lausanne, Switzerland. IN - Venara-Vulpe, Ioana I. Department of Otolaryngology - Head and Neck Surgery, CHUV, University of Lausanne, Lausanne, Switzerland. IN - Alzuphar, Stephen. Department of Otolaryngology - Head and Neck Surgery, CHUV, University of Lausanne, Lausanne, Switzerland. IN - Monnier, Yan. Department of Otolaryngology - Head and Neck Surgery, CHUV, University of Lausanne, Lausanne, Switzerland. IN - Bongiovanni, Massimo. Institute of Pathology, CHUV, University of Lausanne, Lausanne, Switzerland. IN - Hagmann, Patric. Department of Radiology, CHUV, University of Lausanne, Lausanne, Switzerland. IN - Bouchaab, Hanan. Department of Radiation Oncology, CHUV, University of Lausanne, Lausanne, Switzerland. IN - Bourhis, Jean. Department of Radiation Oncology, CHUV, University of Lausanne, Lausanne, Switzerland. IN - Simon, Christian. Department of Otolaryngology - Head and Neck Surgery, CHUV, University of Lausanne, Lausanne, Switzerland. TI - Minimizing adjuvant treatment after transoral robotic surgery through surgical margin revision and exclusion of radiographic extracapsular extension: A Prospective observational cohort study. SO - Head & Neck. 39(5):965-973, 2017 May AS - Head Neck. 39(5):965-973, 2017 May NJ - Head & neck PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - g1p, 8902541 IO - Head Neck CP - United States KW - Functional Outcome Swallowing Scale (FOSS) score; head and neck cancer; head and neck squamous cell carcinoma (HNSCC); oropharyngeal neoplasm; transoral robotic surgery (TORS) AB - BACKGROUND: We investigated in a prospective cohort of patients treated with trans-oral robotic surgery (TORS) for oropharyngeal cancer (OPC), who were selected for the absence of radiographic extra-capsular extension (ECS) and surgically revised for inadequate margins, the possibility of reducing adjuvant radiation (RT)/chemo-radiation therapy (CRT) without jeopardizing tumor control and functional outcome. AB - METHODS: We conducted a prospective observational cohort of patients treated with TORS for oropharyngeal cancer. AB - RESULTS: Twenty-nine patients with T1/2N0 to N2B stage cancers were treated with TORS. Forty-five percent of them were treated for secondary primaries. Nine of 29 patients (31%) were revised for close/positive margins. Adjuvant RT was prescribed for 2 of 19 patients with early squamous cell carcinoma (SCCs) and CRT for 1 of 10 patients with advanced oropharyngeal SCCs. Overall survival (OS), disease-specific survival (DSS), and locoregional control at 2 years were 85%, 96%, and 93%, respectively. Posttreatment Functional Outcome Swallowing Scale (FOSS) scores worsened with prior or adjuvant RT, local recurrence, site, and revision for margins. AB - CONCLUSION: Patients with early and moderately advanced oropharyngeal SCC selected for radiographic ECS and revised for inadequate margins have excellent tumor control and favorable functional recovery. © 2017 Wiley Periodicals, Inc. Head Neck 39: 965-973, 2017. AB - Copyright © 2017 Wiley Periodicals, Inc. ES - 1097-0347 IL - 1043-3074 DO - https://dx.doi.org/10.1002/hed.24712 PT - Journal Article ID - 10.1002/hed.24712 [doi] PP - ppublish PH - 2016/07/04 [received] PH - 2016/10/30 [revised] PH - 2016/12/12 [accepted] LG - English EP - 20170211 DP - 2017 May DC - 20170211 EZ - 2017/02/12 06:00 DA - 2017/02/12 06:00 DT - 2017/02/12 06:00 YR - 2017 RD - 20170414 UP - 20170417 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=28188953 <712. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28107408 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Chin JH AU - Kim WJ AU - Lee J AU - Han YA AU - Lim J AU - Hwang JH AU - Cho SS AU - Kim YK AI - Kim, Young-Kug; ORCID: http://orcid.org/0000-0002-1982-3053 FA - Chin, Ji-Hyun FA - Kim, Wook-Jong FA - Lee, Joonho FA - Han, Yun A FA - Lim, Jinwook FA - Hwang, Jai-Hyun FA - Cho, Seong-Sik FA - Kim, Young-Kug IN - Chin, Ji-Hyun. Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. IN - Kim, Wook-Jong. Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. IN - Lee, Joonho. Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. IN - Han, Yun A. Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. IN - Lim, Jinwook. Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. IN - Hwang, Jai-Hyun. Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. IN - Cho, Seong-Sik. Department of Occupational and Environmental Medicine, Konkuk University Chungju Hospital, Chungju, Republic of Korea. IN - Kim, Young-Kug. Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. TI - Effect of Positive End-Expiratory Pressure on the Sonographic Optic Nerve Sheath Diameter as a Surrogate for Intracranial Pressure during Robot-Assisted Laparoscopic Prostatectomy: A Randomized Controlled Trial. SO - PLoS ONE [Electronic Resource]. 12(1):e0170369, 2017 AS - PLoS ONE. 12(1):e0170369, 2017 NJ - PloS one PI - Journal available in: Electronic-eCollection PI - Citation processed from: Internet JC - 101285081 IO - PLoS ONE CP - United States AB - BACKGROUND: Positive end-expiratory pressure (PEEP) can increase intracranial pressure. Pneumoperitoneum and the Trendelenburg position are associated with an increased intracranial pressure. We investigated whether PEEP ventilation could additionally influence the sonographic optic nerve sheath diameter as a surrogate for intracranial pressure during pneumoperitoneum combined with the Trendelenburg position in patients undergoing robot-assisted laparoscopic prostatectomy. AB - METHODS: After anesthetic induction, 38 patients were randomly allocated to a low tidal volume ventilation (8 ml/kg) without PEEP group (zero end-expiratory pressure [ZEEP] group, n = 19) or low tidal volume ventilation with 8 cmH2O PEEP group (PEEP group, n = 19). The sonographic optic nerve sheath diameter was measured prior to skin incision, 5 min and 30 min after pneumoperitoneum and the Trendelenburg position, and at the end of surgery. The study endpoint was the difference in the sonographic optic nerve sheath diameter 5 min after pneumoperitoneum and the Trendelenburg position between the ZEEP and PEEP groups. AB - RESULTS: Optic nerve sheath diameters 5 min after pneumoperitoneum and the Trendelenburg position did not significantly differ between the groups [least square mean (95% confidence interval); 4.8 (4.6-4.9) mm vs 4.8 (4.7-5.0) mm, P = 0.618]. Optic nerve sheath diameters 30 min after pneumoperitoneum and the Trendelenburg position also did not differ between the groups [least square mean (95% confidence interval); 4.5 (4.3-4.6) mm vs 4.5 (4.4-4.6) mm, P = 0.733]. AB - CONCLUSIONS: An 8 cmH2O PEEP application under low tidal volume ventilation does not induce an increase in the optic nerve sheath diameter during pneumoperitoneum combined with the steep Trendelenburg position, suggesting that there might be no detrimental effects of PEEP on the intracranial pressure during robot-assisted laparoscopic prostatectomy. AB - TRIAL REGISTRATION: ClinicalTrial.gov NCT02516566. CI - The authors have declared that no competing interests exist. ES - 1932-6203 IL - 1932-6203 DI - PONE-D-16-18026 DO - https://dx.doi.org/10.1371/journal.pone.0170369 PT - Journal Article ID - 10.1371/journal.pone.0170369 [doi] ID - PONE-D-16-18026 [pii] ID - PMC5249217 [pmc] PP - epublish PH - 2016/05/04 [received] PH - 2017/01/02 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT02516566 SL - https://clinicaltrials.gov/search/term=NCT02516566 LG - English EP - 20170120 DP - 2017 DC - 20170120 EZ - 2017/01/21 06:00 DA - 2017/01/21 06:00 DT - 2017/01/21 06:00 YR - 2017 RD - 20170410 UP - 20170411 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=28107408 <713. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27724965 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Zhang X AU - Wei J AU - Song X AU - Zhang Y AU - Qian W AU - Sheng L AU - Shen Z AU - Yang L AU - Dong R AU - Gu W FA - Zhang, Xixue FA - Wei, Jionglin FA - Song, Xiaoxing FA - Zhang, Yuhao FA - Qian, Weiqing FA - Sheng, Lu FA - Shen, Zhoujun FA - Yang, Lvjun FA - Dong, Rong FA - Gu, Weidong IN - Zhang, Xixue. Department of Anesthesiology, Huadong Hospital Affiliated to Fudan University, Shanghai, China. IN - Wei, Jionglin. Department of Anesthesiology, Huadong Hospital Affiliated to Fudan University, Shanghai, China. IN - Song, Xiaoxing. Department of Anesthesiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. IN - Zhang, Yuhao. Department of Anesthesiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. IN - Qian, Weiqing. Department of Urology, Huadong Hospital Affiliated to Fudan University, Shanghai, China. IN - Sheng, Lu. Department of Urology, Huadong Hospital Affiliated to Fudan University, Shanghai, China. IN - Shen, Zhoujun. Department of Urology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. IN - Yang, Lvjun. Department of Anesthesiology, Huadong Hospital Affiliated to Fudan University, Shanghai, China. IN - Dong, Rong. Department of Anesthesiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. sally9132@163.com. IN - Gu, Weidong. Department of Anesthesiology, Huadong Hospital Affiliated to Fudan University, Shanghai, China. wdgu_hdh@163.com. TI - Comparison of the impact of prolonged low-pressure and standard-pressure pneumoperitoneum on myocardial injury after robot-assisted surgery in the Trendelenburg position: study protocol for a randomized controlled trial. SO - Trials [Electronic Resource]. 17(1):488, 2016 Oct 10 AS - Trials. 17(1):488, 2016 Oct 10 NJ - Trials PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 101263253 IO - Trials CP - England KW - Low-pressure pneumoperitoneum; Myocardial injury; Robot-assisted urological surgery; Standard-pressure pneumoperitoneum; Trendelenburg position; Troponin T AB - BACKGROUND: Robot-assisted laparoscopic radical prostatectomy and robot-assisted radical cystectomy have gradually become the preferred choices for urologists as they allow surgeons to perform complex procedures more precisely and effectively. The pneumoperitoneum, which is normally applied in these surgeries to provide visual clarity and space to perform the procedure, may cause hemodynamic disturbance, potentially myocardial injury. Thus surgeons have recently considered opting for the low-pressure pneumoperitoneum to lower this negative impact. Herein we describe a protocol for a clinical trial to compare the impact of prolonged low-pressure and standard-pressure pneumoperitoneum on myocardial injury after robot-assisted surgery. AB - METHODS/DESIGN: This study is designed to be a bicenter clinical trial. In total 280 patients scheduled to undergo robot-assisted laparoscopic radical prostatectomy or robot-assisted radical cystectomy will be enrolled and randomized into two groups, with standard- (12-16 mmHg) and low-pressure (7-10 mmHg) pneumoperitoneum, respectively. Troponin T will be measured as the primary endpoint to assess the extent of myocardial injury. Nt-proBNP and hemodynamic indexes will also be recorded for further analysis. AB - DISCUSSION: The significance of this study is emphasized by the fact that there are few studies that have focused on the impact of prolonged pneumoperitoneum on myocardial injury, which is relevant to postoperative mortality. We hope that the conclusions drawn from this study could provide reference and basis to the future of the pneumoperitoneum in clinical practice. AB - TRIAL REGISTRATION: Registered at https://www.clinicaltrials.gov with the Identifier NCT02600481 on November 5, 2015. ES - 1745-6215 IL - 1745-6215 DI - 10.1186/s13063-016-1609-5 DO - https://dx.doi.org/10.1186/s13063-016-1609-5 PT - Journal Article ID - 10.1186/s13063-016-1609-5 [doi] ID - 10.1186/s13063-016-1609-5 [pii] ID - PMC5057242 [pmc] PP - epublish PH - 2015/12/06 [received] PH - 2016/09/17 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT02600481 SL - https://clinicaltrials.gov/search/term=NCT02600481 LG - English EP - 20161010 DP - 2016 Oct 10 DC - 20161011 EZ - 2016/10/12 06:00 DA - 2016/10/12 06:00 DT - 2016/10/12 06:00 YR - 2016 RD - 20170410 UP - 20170411 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27724965 <714. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28238489 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Soto E AU - Luu TH AU - Liu X AU - Magrina JF AU - Wasson MN AU - Einarsson JI AU - Cohen SL AU - Falcone T FA - Soto, Enrique FA - Luu, Thanh Ha FA - Liu, Xiaobo FA - Magrina, Javier F FA - Wasson, Megan N FA - Einarsson, Jon I FA - Cohen, Sarah L FA - Falcone, Tommaso IN - Soto, Enrique. Obstetrics, Gynecology and Women's Health Institute, Cleveland Clinic, Cleveland, Ohio; South Florida Institute for Reproductive Medicine, Miami, Florida; Department of Obstetrics and Gynecology, Herbert Wertheim College of Medicine at Florida International University, Miami, Florida. IN - Luu, Thanh Ha. Obstetrics, Gynecology and Women's Health Institute, Cleveland Clinic, Cleveland, Ohio. IN - Liu, Xiaobo. Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio. IN - Magrina, Javier F. Department of Gynecology, Mayo Clinic Arizona, Scottsdale, Arizona. IN - Wasson, Megan N. Department of Gynecology, Mayo Clinic Arizona, Scottsdale, Arizona. IN - Einarsson, Jon I. Department of Minimally Invasive Gynecology, Brigham and Women's Hospital, Boston, Massachusetts. IN - Cohen, Sarah L. Department of Minimally Invasive Gynecology, Brigham and Women's Hospital, Boston, Massachusetts. IN - Falcone, Tommaso. Obstetrics, Gynecology and Women's Health Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address: falcont@ccf.org. TI - Laparoscopy vs. Robotic Surgery for Endometriosis (LAROSE): a multicenter, randomized, controlled trial. SO - Fertility & Sterility. 107(4):996-1002.e3, 2017 Apr AS - Fertil Steril. 107(4):996-1002.e3, 2017 Apr NJ - Fertility and sterility PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - evf, 0372772 IO - Fertil. Steril. CP - United States KW - Endometriosis; laparoscopy; perioperative outcomes; quality of life; robot-assisted surgery AB - OBJECTIVE: To determine whether the use of the robot for surgical treatment of endometriosis is better than traditional laparoscopy in terms of operative length, perioperative parameters, and quality of life outcomes. AB - DESIGN: Multicenter, randomized clinical trial. AB - SETTING: University teaching hospitals. AB - PATIENT(S): Women aged >18 years with suspected endometriosis who elected to undergo surgical management. AB - INTERVENTION(S): Randomization to conventional or robot-assisted laparoscopic removal of endometriosis. AB - MAIN OUTCOME MEASURE(S): The primary outcome measured was operative time. Secondary outcomes were perioperative complications and quality of life. AB - RESULT(S): The mean operative time for robotic vs. laparoscopic surgery for endometriosis was 106.6 +/- 48.4 minutes vs. 101.6 +/- 63.2 minutes. There were no differences in blood loss, intraoperative or postoperative complications, or rates of conversion to laparotomy in the two arms. Both groups reported significant improvement on condition-specific quality of life outcomes at 6 weeks and 6 months. AB - CONCLUSION(S): There were no differences in perioperative outcomes between robotic and conventional laparoscopy. AB - CLINICAL TRIAL REGISTRATION NUMBER: NCT01556204. AB - Copyright © 2017 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. ES - 1556-5653 IL - 0015-0282 DI - S0015-0282(17)30042-0 DO - https://dx.doi.org/10.1016/j.fertnstert.2016.12.033 PT - Journal Article ID - S0015-0282(17)30042-0 [pii] ID - 10.1016/j.fertnstert.2016.12.033 [doi] PP - ppublish PH - 2016/10/25 [received] PH - 2016/12/09 [revised] PH - 2016/12/27 [accepted] LG - English EP - 20170224 DP - 2017 Apr DC - 20170227 EZ - 2017/02/28 06:00 DA - 2017/02/28 06:00 DT - 2017/02/28 06:00 YR - 2017 RD - 20170403 UP - 20170404 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=28238489 <715. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27283216 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Student V Jr AU - Vidlar A AU - Grepl M AU - Hartmann I AU - Buresova E AU - Student V FA - Student, Vladimir Jr FA - Vidlar, Ales FA - Grepl, Michal FA - Hartmann, Igor FA - Buresova, Eva FA - Student, Vladimir IN - Student, Vladimir Jr. Department of Urology, University Hospital, Olomouc, Czech Republic; Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic. IN - Vidlar, Ales. Department of Urology, University Hospital, Olomouc, Czech Republic; Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic. IN - Grepl, Michal. Department of Urology, University Hospital, Olomouc, Czech Republic; Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic. IN - Hartmann, Igor. Department of Urology, University Hospital, Olomouc, Czech Republic; Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic. IN - Buresova, Eva. Department of Urology, University Hospital, Olomouc, Czech Republic; Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic. IN - Student, Vladimir. Department of Urology, University Hospital, Olomouc, Czech Republic; Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic. Electronic address: studentv@seznam.cz. TI - Advanced Reconstruction of Vesicourethral Support (ARVUS) during Robot-assisted Radical Prostatectomy: One-year Functional Outcomes in a Two-group Randomised Controlled Trial. SO - European Urology. 71(5):822-830, 2017 May AS - Eur Urol. 71(5):822-830, 2017 May NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. CP - Switzerland KW - Anastomosis; Continence; Erectile function; Functional reconstruction; Prostate cancer; Robot-assisted radical prostatectomy AB - BACKGROUND: The advent of robotics has facilitated new surgical techniques for radical prostatectomy. These allow adjustment of pelvic anatomical and functional relationships after removal of the prostate to ameliorate postprostatectomy incontinence (PPI) and reduce the time to complete continence. AB - OBJECTIVES: To describe the results of a new surgical technique for reconstruction of vesicourethral anastomosis using the levator ani muscle for support during robot-assisted radical prostatectomy (RARP). AB - DESIGN, SETTING, AND PARTICIPANTS: A prospective, randomised, single-blind study among 66 consecutive patients with localised prostate cancer (cT1-2N0M0) undergoing RARP from June to September 2014, 32 using the new technique and 34 using the standard posterior reconstruction according to Rocco. AB - SURGICAL PROCEDURE: In the advanced reconstruction of vesicourethral support (ARVUS) intervention group, the fibres of the levator ani muscle, Denonvilliers fascia, retrotrigonal layer, and median dorsal raphe were used to form the dorsal support for the urethrovesical anastomosis. Suture of the arcus tendineus to the bladder neck served as the anterior fixation. AB - MEASUREMENTS: We compared demographic data and preoperative and postoperative functional and oncologic results for the two groups. The primary endpoint was continence evaluated at different time points (24h, 2, 4, and 8 wk, and 6 and 12 mo). The secondary endpoints were perioperative and postoperative complications and erectile function. AB - RESULTS AND LIMITATIONS: Using a continence definition of 0 pads/d, the continence rates for the ARVUS versus the control group were 21.9% versus 5.9% at 24h (p=0.079), 43.8% versus 11.8% at 2 wk (p=0.005), 62.5% versus 14.7% at 4 wk (p<0.001), 68.8% versus 20.6% at 8 wk (p<0.001), 75.0% versus 44.1% at 6 mo (p=0.013), and 86.66% versus 61.29% at 12 mo (p=0.04). International Index of Erectile Function questionnaire results at 6 and 12 mo after surgery showed similar potency rates for the control group (40.0% and 73.33%) and the ARVUS group (38.8% and 72.22%). There were four postoperative complications (2 in each group): three haematomas requiring transfusion and one lymphocele that needed drainage. No urinary retention, anastomosis leak, or perineal pain was observed. Limitations include the small sample size and the single-institution design. AB - CONCLUSIONS: The ARVUS technique yielded better urinary continence results than standard posterior reconstruction, with no negative impact on erectile function, complication rate, or oncologic outcome. External validation is warranted before clear recommendations can be made. AB - PATIENT SUMMARY: We showed that postprostatectomy incontinence can be assuaged using a new technique for vesicourethral anastomosis reconstruction during robot-assisted radical prostatectomy (RARP). This could significantly improve the quality of life of patients after RARP. More studies are needed to support our results. AB - Copyright © 2016 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(16)30201-9 DO - https://dx.doi.org/10.1016/j.eururo.2016.05.032 PT - Journal Article ID - S0302-2838(16)30201-9 [pii] ID - 10.1016/j.eururo.2016.05.032 [doi] PP - ppublish PH - 2016/03/03 [received] PH - 2016/05/23 [accepted] LG - English EP - 20160606 DP - 2017 May DC - 20160610 EZ - 2016/06/11 06:00 DA - 2016/06/11 06:00 DT - 2016/06/11 06:00 YR - 2017 RD - 20170402 UP - 20170404 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27283216 <716. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26947602 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Montorsi F AU - Oelke M AU - Henneges C AU - Brock G AU - Salonia A AU - d'Anzeo G AU - Rossi A AU - Mulhall JP AU - Buttner H FA - Montorsi, Francesco FA - Oelke, Matthias FA - Henneges, Carsten FA - Brock, Gerald FA - Salonia, Andrea FA - d'Anzeo, Gianluca FA - Rossi, Andrea FA - Mulhall, John P FA - Buttner, Hartwig IN - Montorsi, Francesco. Department of Urology, Vita Salute San Raffaele University, Milan, Italy. Electronic address: napoli.patrizia@hsr.it. IN - Oelke, Matthias. Department of Urology and Urological Oncology, Hanover Medical School, Hanover, Germany. IN - Henneges, Carsten. Global Statistical Sciences, EU Statistics, Lilly Deutschland GmbH, Bad Homburg, Germany. IN - Brock, Gerald. Department of Surgery, Division of Urology, University of Western Ontario, London, Ontario, Canada. IN - Salonia, Andrea. Department of Urology, Vita Salute San Raffaele University, Milan, Italy. IN - d'Anzeo, Gianluca. Therapeutic Area Men's Health, Eli Lilly SpA, Florence, Italy. IN - Rossi, Andrea. Therapeutic Area Men's Health, Eli Lilly SpA, Florence, Italy. IN - Mulhall, John P. Memorial Sloan Kettering Cancer Center, New York, NY, USA. IN - Buttner, Hartwig. Biomedicines BU, Lilly Deutschland GmbH, Bad Homburg, Germany. TI - Exploratory Decision-Tree Modeling of Data from the Randomized REACTT Trial of Tadalafil Versus Placebo to Predict Recovery of Erectile Function After Bilateral Nerve-Sparing Radical Prostatectomy. SO - European Urology. 70(3):529-37, 2016 Sep AS - Eur Urol. 70(3):529-37, 2016 Sep NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. SB - Index Medicus CP - Switzerland KW - Clinical trials; Decision-tree analysis; Erectile dysfunction; Nerve-sparing radical prostatectomy; Phosphodiesterase type 5 inhibitors; Predictors; Prostate cancer; Rehabilitation; Tadalafil AB - BACKGROUND: Understanding predictors for the recovery of erectile function (EF) after nerve-sparing radical prostatectomy (nsRP) might help clinicians and patients in preoperative counseling and expectation management of EF rehabilitation strategies. AB - OBJECTIVE: To describe the effect of potential predictors on EF recovery after nsRP by post hoc decision-tree modeling of data from A Study of Tadalafil After Radical Prostatectomy (REACTT). AB - DESIGN, SETTING, AND PARTICIPANTS: Randomized double-blind double-dummy placebo-controlled trial in 423 men aged <68 yr with adenocarcinoma of the prostate (Gleason <7, normal preoperative EF) who underwent nsRP at 50 centers from nine European countries and Canada. AB - INTERVENTION: Postsurgery 1:1:1 randomization to 9-mo double-blind treatment with tadalafil 5mg once a day (OaD), tadalafil 20mg on demand, or placebo, followed by a 6-wk drug-free-washout, and a 3-mo open-label tadalafil OaD treatment. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Three decision-tree models, using the International Index of Erectile Function-Erectile Function (IIEF-EF) domain score at the end of double-blind treatment, washout, and open-label treatment as response variable. Each model evaluated the association between potential predictors: presurgery IIEF domain and IIEF single-item scores, surgical approach, nerve-sparing score (NSS), and postsurgery randomized treatment group. AB - RESULTS AND LIMITATIONS: The first decision-tree model (n=422, intention-to-treat population) identified high presurgery sexual desire (IIEF item 12: >3.5 and <3.5) as the key predictor for IIEF-EF at the end of double-blind treatment (mean IIEF-EF: 14.9 and 11.1), followed by high confidence to get and maintain an erection (IIEF item 15: >3.5 and <3.5; IIEF-EF: 15.4 and 7.1). For patients meeting these criteria, additional non-IIEF-related predictors included robot-assisted laparoscopic surgery (yes or no; IIEF-EF: 19.3 and 12.6), quality of nerve sparing (NSS: <2.5 and >2.5; IIEF-EF: 14.3 and 10.5), and treatment with tadalafil OaD (yes and no; IIEF-EF: 17.6 and 14.3). Additional analyses after washout and open-label treatment identified high presurgery intercourse satisfaction as the key predictor. AB - CONCLUSIONS: Exploratory decision-tree analyses identified high presurgery sexual desire, confidence, and intercourse satisfaction as key predictors for EF recovery. Patients meeting these criteria might benefit the most from conserving surgery and early postsurgery EF rehabilitation. Strategies for improving EF after surgery should be discussed preoperatively with all patients; this information may support expectation management for functional recovery on an individual patient level. AB - PATIENT SUMMARY: Understanding how patient characteristics and different treatment options affect the recovery of erectile function (EF) after radical surgery for prostate cancer might help physicians select the optimal treatment for their patients. This analysis of data from a clinical trial suggested that high presurgery sexual desire, sexual confidence, and intercourse satisfaction are key factors predicting EF recovery. Patients meeting these criteria might benefit the most from conserving surgery (robot-assisted surgery, perfect nerve sparing) and postsurgery medical rehabilitation of EF. AB - TRIAL REGISTRATION: ClinicalTrials.gov, NCT01026818. AB - Copyright © 2016. Published by Elsevier B.V. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(16)00214-1 DO - https://dx.doi.org/10.1016/j.eururo.2016.02.036 PT - Journal Article ID - S0302-2838(16)00214-1 [pii] ID - 10.1016/j.eururo.2016.02.036 [doi] PP - ppublish PH - 2015/06/26 [received] PH - 2016/02/11 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01026818 SL - https://clinicaltrials.gov/search/term=NCT01026818 GI - No: P30 CA008748 Organization: (CA) *NCI NIH HHS* Country: United States LG - English EP - 20160303 DP - 2016 Sep DC - 20160806 EZ - 2016/03/08 06:00 DA - 2016/03/08 06:00 DT - 2016/03/08 06:00 YR - 2016 RD - 20170316 UP - 20170317 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=26947602 <717. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28216290 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Process AU - Jensen JS AU - Antonsen HK AU - Durup J FA - Jensen, Jonas Sanberg FA - Antonsen, Henning Kold FA - Durup, Jesper IN - Jensen, Jonas Sanberg. Department of General Surgery, Kolding Hospital, Skovvangen 2-8, DK-6000 Kolding, Denmark. Electronic address: jsanberg@dadlnet.dk. IN - Antonsen, Henning Kold. Department of General Surgery, Kolding Hospital, Skovvangen 2-8, DK-6000 Kolding, Denmark. IN - Durup, Jesper. Department of Surgery A, Odense University Hospital, Sdr Boulevard 29, DK-5000 Odense C, Denmark. TI - Two years of experience with robot-assisted anti-reflux surgery: A retrospective cohort study. SO - International Journal Of Surgery. 39:260-266, 2017 Mar AS - Int J Surg. 39:260-266, 2017 Mar NJ - International journal of surgery (London, England) PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101228232 IO - Int J Surg CP - England KW - Follow-up studies; Fundoplication; Gastroesophageal reflux; Laparoscopy; Robotic surgical procedures; Treatment outcome AB - BACKGROUND AND AIMS: Robot-assisted anti-reflux surgery (RAAS) is an alternative to conventional laparoscopic anti-reflux surgery (CLAS). The purpose of this study was to evaluate initial Danish experiences with robot-assisted anti-reflux surgery compared to conventional laparoscopic anti-reflux surgery incorporating follow-up and evaluation of possible learning curve. AB - MATERIAL AND METHODS: Patients undergoing primary RAAS or CLAS at The Department of Surgery A, Odense University Hospital and The Department of General Surgery, Kolding Hospital from April 2013 to April 2015 was included. Demographic data, comorbidity, docking time, length of procedure, type of fundic wrap as well as perioperative complications and postoperative complications, need for reoperation or any upper gastrointestinal endoscopy from surgery to final follow-up was retrospectively extracted from patient records. AB - RESULTS: 103 patients were included in this study. 39 patients underwent RAAS and 64 patients underwent CLAS. There were no statistically significant differences in demographic data or comorbidities except distribution of heart disease (RAAS: 5.1% vs. CLAS: 18.8%, p = 0.05) and previous abdominal surgery (RAAS: 28.2% vs. CLAS: 48.4%, p = 0.04). Duration of surgery was significantly increased in patients undergoing RAAS (RAAS: 135 +/- 27 min vs. CLAS: 86 +/- 19 min, p < 0.01). There was no statistical significant difference in intraoperative complications (p = 0.20), 30-day postoperative complication rate (p = 0.20) or mortality (p = 1.00). At follow-up in April 2016, there were no statistically significant differences in patients having undergone upper endoscopy postoperatively (p = 0.92), the use of anti-secretory drugs (p = 0.46) or patients having undergone reoperation (p = 0.60). Reasons for reoperation were significantly dependent on type of fundic wrap with reoperation of Nissen fundoplication being dysphagia and reoperation of Toupet being recurrent reflux (p = 0.008). There was no clearly determined learning curve. AB - CONCLUSIONS: RAAS was safe, feasible and with equal efficacy to CLAS. There were however no particular advantages to performing antireflux surgery as robot-assisted procedures neither intra-operatively nor at follow-up. AB - Copyright © 2017 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved. ES - 1743-9159 IL - 1743-9159 DI - S1743-9191(17)30137-1 DO - https://dx.doi.org/10.1016/j.ijsu.2017.02.014 PT - Journal Article ID - S1743-9191(17)30137-1 [pii] ID - 10.1016/j.ijsu.2017.02.014 [doi] PP - ppublish PH - 2016/09/29 [received] PH - 2017/02/05 [revised] PH - 2017/02/08 [accepted] LG - English EP - 20170213 DP - 2017 Mar DC - 20170220 EZ - 2017/02/21 06:00 DA - 2017/02/22 06:00 DT - 2017/02/22 06:00 YR - 2017 RD - 20170310 UP - 20170313 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=28216290 <718. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28099699 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Process AU - Deimling TA AU - Eldridge JL AU - Riley KA AU - Kunselman AR AU - Harkins GJ FA - Deimling, Timothy A FA - Eldridge, Jennifer L FA - Riley, Kristin A FA - Kunselman, Allen R FA - Harkins, Gerald J IN - Deimling, Timothy A. Division of Minimally Invasive GYN Surgery, Department of Obstetrics and Gynecology, Milton S Hershey Medical Center, Penn State University, Hershey, PA, USA. IN - Eldridge, Jennifer L. Division of Minimally Invasive GYN Surgery, Department of Obstetrics and Gynecology, Milton S Hershey Medical Center, Penn State University, Hershey, PA, USA. IN - Riley, Kristin A. Division of Minimally Invasive GYN Surgery, Department of Obstetrics and Gynecology, Milton S Hershey Medical Center, Penn State University, Hershey, PA, USA. IN - Kunselman, Allen R. Division of Biostatistics and Bioinformatics, Department of Public Health Sciences, Milton S Hershey Medical Center, Penn State University, Hershey, PA, USA. IN - Harkins, Gerald J. Division of Minimally Invasive GYN Surgery, Department of Obstetrics and Gynecology, Milton S Hershey Medical Center, Penn State University, Hershey, PA, USA. TI - Randomized controlled trial comparing operative times between standard and robot-assisted laparoscopic hysterectomy. SO - International Journal of Gynaecology & Obstetrics. 136(1):64-69, 2017 Jan AS - Int J Gynaecol Obstet. 136(1):64-69, 2017 Jan NJ - International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - e4t, 0210174 IO - Int J Gynaecol Obstet CP - United States KW - Hysterectomy; Laparoscopic; Minimally invasive; Operative time; Robotic-assisted AB - OBJECTIVE: To compare the operative time between robot-assisted laparoscopic hysterectomies and standard laparoscopic hysterectomies. AB - METHODS: A prospective, randomized controlled trial enrolled women aged 18-80 years attending Penn State Hershey Medical Center between April 23 and October 20, 2014 to undergo hysterectomy. Participants were randomized using a random number generator to undergo either robot-assisted or standard laparoscopic hysterectomy. The primary outcome was the total operative time (surgeon incision to surgeon stop, including robot docking time, if applicable). Intention-to-treat analyses were performed and the operative time was compared between the two treatments for non-inferiority, defined as a difference in operative time of no longer than 15 minutes. AB - RESULTS: There were 72 patients randomized to each treatment arm. The mean operative time was 73.9 minutes (median 67.0 minutes; interquartile range 59.0-83.0 minutes) in the robot-assisted hysterectomy group and 74.9 minutes (median 65.5 minutes; interquartile range 57.0-90.5 minutes) in the standard laparoscopic hysterectomy group. The upper bound of the 95% confidence interval of the difference in operative time was 6.6 minutes, below the 15-minute measure of non-inferiority. AB - CONCLUSION: When performed by a surgeon experienced in both techniques, the operative time for robot-assisted laparoscopic hysterectomy was non-inferior to that achieved with standard laparoscopic hysterectomy. CLINICALTRIALS.GOV: NCT02118974. AB - Copyright © 2016 International Federation of Gynecology and Obstetrics. CI - G.J.H. was a proctor for Ethicon and Intuitive Surgical during the study period. A.R.K. owns stock in Merck. The authors have no other conflicts of interest. ES - 1879-3479 IL - 0020-7292 DO - https://dx.doi.org/10.1002/ijgo.12001 PT - Journal Article ID - 10.1002/ijgo.12001 [doi] ID - PMC5245181 [pmc] ID - NIHMS821149 [mid] PP - ppublish PH - 2016/06/08 [received] PH - 2016/08/01 [revised] PH - 2016/09/29 [accepted] PH - 2018/01/01 [pmc-release] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT02118974 SL - https://clinicaltrials.gov/search/term=NCT02118974 GI - No: UL1 TR000127 Organization: (TR) *NCATS NIH HHS* Country: United States No: UL1 TR002014 Organization: (TR) *NCATS NIH HHS* Country: United States LG - English EP - 20161103 DP - 2017 Jan DC - 20170118 EZ - 2017/01/19 06:00 DA - 2017/01/19 06:00 DT - 2017/01/19 06:00 YR - 2017 RD - 20170308 UP - 20170309 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=28099699 <719. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28027975 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Vargas MV AU - Moawad G AU - Denny K AU - Happ L AU - Misa NY AU - Margulies S AU - Opoku-Anane J AU - Abi Khalil E AU - Marfori C FA - Vargas, Maria V FA - Moawad, Gaby FA - Denny, Kathryn FA - Happ, Lindsey FA - Misa, Nana Yaa FA - Margulies, Samantha FA - Opoku-Anane, Jessica FA - Abi Khalil, Elias FA - Marfori, Cherie IN - Vargas, Maria V. Division of Gynecology, George Washington University Medical Faculty Associates, Washington, DC. Electronic address: mvvargas@mfa.gwu.edu. IN - Moawad, Gaby. Division of Gynecology, George Washington University Medical Faculty Associates, Washington, DC. IN - Denny, Kathryn. School of Medicine and Health Sciences, George Washington University, Washington, DC. IN - Happ, Lindsey. Milken Institute of Public Health, George Washington University, Washington, DC. IN - Misa, Nana Yaa. School of Medicine and Health Sciences, George Washington University, Washington, DC. IN - Margulies, Samantha. School of Medicine and Health Sciences, George Washington University, Washington, DC. IN - Opoku-Anane, Jessica. Division of Gynecology, George Washington University Medical Faculty Associates, Washington, DC. IN - Abi Khalil, Elias. Division of Gynecology, George Washington University Medical Faculty Associates, Washington, DC. IN - Marfori, Cherie. Division of Gynecology, George Washington University Medical Faculty Associates, Washington, DC. TI - Transferability of Virtual Reality, Simulation-Based, Robotic Suturing Skills to a Live Porcine Model in Novice Surgeons: A Single-Blind Randomized Controlled Trial. SO - Journal of Minimally Invasive Gynecology. 24(3):420-425, 2017 Mar - Apr AS - J Minim Invasive Gynecol. 24(3):420-425, 2017 Mar - Apr NJ - Journal of minimally invasive gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101235322 IO - J Minim Invasive Gynecol CP - United States KW - Proficiency-based training; Robotic surgery; Simulation; Virtual reality simulation; da Vinci Surgical Simulator; da Vinci Surgical System AB - STUDY OBJECTIVE: To assess whether a robotic simulation curriculum for novice surgeons can improve performance of a suturing task in a live porcine model. AB - DESIGN: Randomized controlled trial (Canadian Task Force classification I). AB - SETTING: Academic medical center. AB - PATIENTS: Thirty-five medical students without robotic surgical experience. AB - INTERVENTIONS: Participants were enrolled in an online session of training modules followed by an in-person orientation. Baseline performance testing on the Mimic Technologies da Vinci Surgical Simulator (dVSS) was also performed. Participants were then randomly assigned to the completion of 4 dVSS training tasks (camera clutching 1, suture sponge 1 and 2, and tubes) versus no further training. The intervention group performed each dVSS task until proficiency or up to 10 times. A final suturing task was performed on a live porcine model, which was video recorded and blindly assessed by experienced surgeons. The primary outcomes were Global Evaluative Assessment of Robotic Skills (GEARS) scores and task time. The study had 90% power to detect a mean difference of 3 points on the GEARS scale, assuming a standard deviation (SD) of 2.65, and 80% power to detect a mean difference of 3 minutes, assuming an SD of 3 minutes. AB - MEASUREMENTS AND MAIN RESULTS: There were no differences in demographics and baseline skills between the 2 groups. No significant differences in task time in minutes or GEARS scores were seen for the final suturing task between the intervention and control groups, respectively (9.2 [2.65] vs 9.9 [2.07] minutes, p = .406; and 15.37 [2.51] vs 15.25 [3.38], p = .603). The 95% confidence interval for the difference in mean task times was -2.36 to .96 minutes and for mean GEARS scores -1.91 to 2.15 points. AB - CONCLUSIONS: Live suturing task performance was not improved with a proficiency-based virtual reality simulation suturing curriculum compared with standard orientation to the da Vinci robotic console in a group of novice surgeons. AB - Copyright Published by Elsevier Inc. ES - 1553-4669 IL - 1553-4650 DI - S1553-4650(16)31285-7 DO - https://dx.doi.org/10.1016/j.jmig.2016.12.016 PT - Journal Article ID - S1553-4650(16)31285-7 [pii] ID - 10.1016/j.jmig.2016.12.016 [doi] PP - ppublish PH - 2016/10/14 [received] PH - 2016/12/16 [revised] PH - 2016/12/16 [accepted] LG - English EP - 20161224 DP - 2017 Mar - Apr DC - 20161228 EZ - 2016/12/29 06:00 DA - 2016/12/29 06:00 DT - 2016/12/29 06:00 YR - 2017 RD - 20170308 UP - 20170309 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=28027975 <720. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27334135 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Process AU - Harke N AU - Godes M AU - Habibzada J AU - Urbanova K AU - Wagner C AU - Zecha H AU - Addali M AU - Witt JH FA - Harke, Nina FA - Godes, Michael FA - Habibzada, Jawid FA - Urbanova, Katarina FA - Wagner, Christian FA - Zecha, Henrik FA - Addali, Mustapha FA - Witt, Jorn H IN - Harke, Nina. Department of Urology, Pediatric Urology and Urologic Oncology - Prostate Center Northwest, St. Antonius Hospital, Moellenweg 22, 48599, Gronau, Germany. harkenina@gmail.com. IN - Godes, Michael. Department of Urology, Pediatric Urology and Urologic Oncology - Prostate Center Northwest, St. Antonius Hospital, Moellenweg 22, 48599, Gronau, Germany. IN - Habibzada, Jawid. Department of Urology, Pediatric Urology and Urologic Oncology - Prostate Center Northwest, St. Antonius Hospital, Moellenweg 22, 48599, Gronau, Germany. IN - Urbanova, Katarina. Department of Urology, Pediatric Urology and Urologic Oncology - Prostate Center Northwest, St. Antonius Hospital, Moellenweg 22, 48599, Gronau, Germany. IN - Wagner, Christian. Department of Urology, Pediatric Urology and Urologic Oncology - Prostate Center Northwest, St. Antonius Hospital, Moellenweg 22, 48599, Gronau, Germany. IN - Zecha, Henrik. Department of Urology, Pediatric Urology and Urologic Oncology - Prostate Center Northwest, St. Antonius Hospital, Moellenweg 22, 48599, Gronau, Germany. IN - Addali, Mustapha. Department of Urology, Pediatric Urology and Urologic Oncology - Prostate Center Northwest, St. Antonius Hospital, Moellenweg 22, 48599, Gronau, Germany. IN - Witt, Jorn H. Department of Urology, Pediatric Urology and Urologic Oncology - Prostate Center Northwest, St. Antonius Hospital, Moellenweg 22, 48599, Gronau, Germany. TI - Postoperative patient comfort in suprapubic drainage versus transurethral catheterization following robot-assisted radical prostatectomy: a prospective randomized clinical trial. SO - World Journal of Urology. 35(3):389-394, 2017 Mar AS - World J Urol. 35(3):389-394, 2017 Mar NJ - World journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - bry, 8307716 IO - World J Urol CP - Germany KW - Discomfort; Radical prostatectomy; Suprapubic tube; Urethral catheter; Urinary drainage AB - PURPOSE: To evaluate the impact of the type of urinary diversion (suprapubic vs. transurethral catheterization) on patients' postoperative pain after radical prostatectomy, development of bacteriuria and long-term functional results. AB - METHODS: A randomized, prospective clinical trial was performed including 160 patients who underwent robot-assisted radical prostatectomy after randomization into two groups: intraoperatively, a transurethral catheter (control group) or an additional suprapubic tube (with removal of the transurethral catheter in the morning of postoperative day 1; intervention group) was placed. Primary study endpoint was postoperative pain objectified by the numeric rating scale questionnaire. Secondary endpoints were bacteriuria after catheter removal and functional outcomes after up to 2 years of follow-up. AB - RESULTS: There were no significant differences in demographic and perioperative data. Starting on postoperative day 2, patients in the suprapubic diversion group had significantly less pain on every time point preceding the removal of the catheter compared to the control cohort with a median overall numeric rating score on postoperative day 1-4 of 2.4 points in the transurethral versus 1.3 in the intervention group (p = 0.012). No statistical difference was found in postoperative bacteriuria and complications as well as in functional results, quality of life and incontinence rates after a median follow-up of 22 months. AB - CONCLUSIONS: Suprapubic drainage in robot-assisted radical prostatectomy shows significantly decreased pain levels during the catheterization period compared to the transurethral diversion without compromising long-term functional results. Intraoperative placement of a suprapubic tube should be discussed as a standard procedure for further improvement of patients' postoperative comfort. ES - 1433-8726 IL - 0724-4983 DI - 10.1007/s00345-016-1883-6 DO - https://dx.doi.org/10.1007/s00345-016-1883-6 PT - Journal Article ID - 27334135 [pubmed] ID - 10.1007/s00345-016-1883-6 [doi] ID - 10.1007/s00345-016-1883-6 [pii] PP - ppublish PH - 2016/04/17 [received] PH - 2016/06/13 [accepted] LG - English EP - 20160622 DP - 2017 Mar DC - 20160623 EZ - 2016/06/24 06:00 DA - 2016/06/24 06:00 DT - 2016/06/24 06:00 YR - 2017 RD - 20170302 UP - 20170303 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27334135 <721. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28099744 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Process AU - Harris JA AU - Uppal S AU - Kamdar N AU - Swenson CW AU - Campbell D AU - Morgan DM FA - Harris, John A FA - Uppal, Shitanshu FA - Kamdar, Neil FA - Swenson, Carolyn W FA - Campbell, Darrell FA - Morgan, Daniel M IN - Harris, John A. Division of Women's Health, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA. IN - Uppal, Shitanshu. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA. IN - Kamdar, Neil. Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA. IN - Swenson, Carolyn W. Division of Urogynecology, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA. IN - Campbell, Darrell. Department of Surgery, University of Michigan, Ann Arbor, MI, USA. IN - Morgan, Daniel M. Division of Urogynecology, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA. TI - A retrospective cohort study of hemostatic agent use during hysterectomy and risk of post-operative complications. SO - International Journal of Gynaecology & Obstetrics. 136(2):232-237, 2017 Feb AS - Int J Gynaecol Obstet. 136(2):232-237, 2017 Feb NJ - International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - e4t, 0210174 IO - Int J Gynaecol Obstet CP - United States KW - Blood transfusions; Complications; Hemostatic agents; Hospital readmissions; Hysterectomy; Pelvic abscess; Propensity score matching AB - OBJECTIVE: To determine if the use of intraoperative hemostatic agents was a risk factor for post-operative adverse events within 30 days of patients undergoing hysterectomy. AB - METHOD: A population-based retrospective cohort study included data from patients undergoing hysterectomy for any indication between January 1, 2013, and December 31, 2014, at 52 hospitals in Michigan, USA. Any individuals with missing covariate data were excluded, and multivariable logistic regression and propensity score-matching were used to estimate the rate of post-operative adverse events associated with intra-operative hemostatic agents independent of demographic and surgical factors. AB - RESULTS: There were 17 960 surgical procedures included in the analysis, with 4659 (25.9%) that included the use of hemostatic agents. Hemostatic agent use was associated with an increase in predicted hospital re-admissions (P=0.007). Among all hysterectomy approaches, and after adjusting for demographic and surgical factors, hemostatic agent use during robotic-assisted laparoscopic hysterectomy was associated with an increased predicted rate of blood transfusions (P=0.019), an increased predicted rate of pelvic abscess diagnoses (P=0.001), an increased predicted rate of hospital re-admission (P=0.001), and an increased predicted rate of re-operation (P=0.021). AB - CONCLUSION: Hemostatic agents should be used carefully owing to associations with increased post-operative re-admissions and re-operations when used during hysterectomy. AB - Copyright © 2016 International Federation of Gynecology and Obstetrics. CI - The authors have no conflicts of interest ES - 1879-3479 IL - 0020-7292 DO - https://dx.doi.org/10.1002/ijgo.12037 PT - Journal Article ID - 28099744 [pubmed] ID - 10.1002/ijgo.12037 [doi] ID - PMC5245183 [pmc] ID - NIHMS828227 [mid] PP - ppublish PH - 2016/06/21 [received] PH - 2016/09/07 [revised] PH - 2016/11/03 [accepted] PH - 2018/02/01 [pmc-release] GI - No: K12 HD063087 Organization: (HD) *NICHD NIH HHS* Country: United States No: K12 HD065257 Organization: (HD) *NICHD NIH HHS* Country: United States LG - English EP - 20161116 DP - 2017 Feb DC - 20170118 EZ - 2017/01/19 06:00 DA - 2017/01/19 06:00 DT - 2017/01/19 06:00 YR - 2017 RD - 20170224 UP - 20170228 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=28099744 <722. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27180224 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Mueller ER AU - Kenton K AU - Anger JT AU - Bresee C AU - Tarnay C FA - Mueller, Elizabeth Rose FA - Kenton, Kimberly FA - Anger, Jennifer T FA - Bresee, Catherine FA - Tarnay, Christopher IN - Mueller, Elizabeth Rose. Departments of Obstetrics/Gynecology and Urology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois. Electronic address: emuelle@lumc.edu. IN - Kenton, Kimberly. Departments of Obstetrics/Gynecology and Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. IN - Anger, Jennifer T. Division of Urology, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California. IN - Bresee, Catherine. Biostatistics and Bioinformatics Research Center, Cedars-Sinai Medical Center, Los Angeles, California. IN - Tarnay, Christopher. Department of Obstetrics/Gynecology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California. TI - Cosmetic Appearance of Port-site Scars 1 Year After Laparoscopic Versus Robotic Sacrocolpopexy: A Supplementary Study of the ACCESS Clinical Trial. SO - Journal of Minimally Invasive Gynecology. 23(6):917-21, 2016 Sep-Oct AS - J Minim Invasive Gynecol. 23(6):917-21, 2016 Sep-Oct NJ - Journal of minimally invasive gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101235322 IO - J Minim Invasive Gynecol PM - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007204 OI - Source: NLM. NIHMS786413 [Available on 09/01/17] SB - Index Medicus CP - United States KW - Laparoscopic; Prolapse; Robotic; Sacrocolpopexy; Scar; Wound healing AB - STUDY OBJECTIVE: To prospectively measure trocar site appearances 1 year after surgery in women participants in the Abdominal Colpopexy: Comparison of Endoscopic Surgical Strategies Trial, a 2-center randomized surgical trial (NCT01124916). AB - DESIGN: Supplementary analysis of a surgical trial that randomized women to robotic or laparoscopic sacrocolpopexy (Canadian Task Force classification I). AB - SETTING: Operative trial. AB - PATIENTS: Women undergoing clinically indicated sacrocolpopexy for symptomatic stage >II pelvic organ prolapse were randomized to laparoscopic abdominal sacrocolpopexy (LASC) or robotic abdominal sacrocolpopexy (RASC). Trocar skin incision closure was standardized by using Dermabond (Ethicon, Somerville, NJ). AB - MEASUREMENTS AND MAIN RESULTS: Photographs of all incision sites were taken at baseline (immediately), 6 weeks, 6 months, and 1 year after surgery. Study coordinators scored each incision with the validated Stony Brook Evaluation Scale (SBES), a 5-point wound evaluation scale. We calculated the average of all scars scores per case to determine the percent of optimal wound healing (0%-100%) for each case as well as the proportion of cases meeting 100% wound repair scoring. Wound repair scores across groups were tested with the Wilcoxon rank sum test. The overall proportion of cases in each group meeting "optimal" wound recovery (scores of 100%) was tested with the Fisher exact test. Seventy-eight women with a mean age of 59 years (range, 26-79 years) were randomized to LASC (n = 38) or RASC (n = 40). We did not detect significant differences in baseline characteristics or rates of dropout between the 2 study groups (5 in LASC and 7 in RASC, p = .60). Pain in the initial postoperative period was higher in the robotic arm although groups were similar at 2 weeks. Nearly all cases (75/78) contributed wound repair data (36 laparoscopic and 39 robotic). Laparoscopic surgeries require significantly fewer incisions (median = 4; range, 4-6) than robotic surgeries (median = 5; range, 4-6; p < .001). SBES scores at 6 weeks were not different for LASC and RASC (p = .426). By 6 months, the scores were better in the LASC group (84.8% +/- 8.8% vs 78.5% +/- 7.2%, p = .031), and this finding remained at 1 year (93.4% +/- 7.2% vs 85.9% +/- 8.8%, p = .001). The proportion of cases with optimal wound repair (score of 100%) was higher in the laparoscopic arm at 1 year after surgery (12/27 vs 4/33, p = .008). AB - INTERVENTIONS: Women were randomized to robotic assisted laparoscopy or laparoscopy. AB - CONCLUSION: Wound appearance using the SBES was better in the LASC group, suggesting that there may be alterations in the mechanism for wound initiation and/or healing based on the minimally invasive route used for sacrocolpopexy. AB - Copyright © 2016 AAGL. Published by Elsevier Inc. All rights reserved. CI - Anger JA: Investigator ASTORA Women's Health LLC; investigator/expert witness for Boston Scientific Breese C: Nothing to disclose Kenton K: Grant from Boston Scientific Mueller ER: Nothing to disclose Tarney C: Nothing to disclose ES - 1553-4669 IL - 1553-4650 DI - S1553-4650(16)30072-3 DO - https://dx.doi.org/10.1016/j.jmig.2016.05.001 PT - Journal Article ID - 27180224 [pubmed] ID - S1553-4650(16)30072-3 [pii] ID - 10.1016/j.jmig.2016.05.001 [doi] ID - PMC5007204 [pmc] ID - NIHMS786413 [mid] PP - ppublish PH - 2016/03/16 [received] PH - 2016/04/22 [revised] PH - 2016/05/02 [accepted] PH - 2017/09/01 [pmc-release] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01124916 SL - https://clinicaltrials.gov/search/term=NCT01124916 GI - No: L30 DK089590 Organization: (DK) *NIDDK NIH HHS* Country: United States No: RC1 EB010649 Organization: (EB) *NIBIB NIH HHS* Country: United States LG - English EP - 20160512 DP - 2016 Sep-Oct DC - 20160831 EZ - 2016/05/16 06:00 DA - 2016/05/18 06:00 DT - 2016/05/18 06:00 YR - 2016 RD - 20170224 UP - 20170228 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27180224 <723. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28159014 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Strandby RB AU - Ambrus R AU - Secher NH AU - Goetze JP AU - Achiam MP AU - Svendsen LB FA - Strandby, Rune Broni FA - Ambrus, Rikard FA - Secher, Niels H FA - Goetze, Jens Peter FA - Achiam, Michael Patrick FA - Svendsen, Lars Bo IN - Strandby, Rune Broni. Department of Surgical Gastroenterology, University of Copenhagen, Rigshospitalet, Blegdamsvej 9, DK-2100, Copenhagen-O, Denmark. rune.broni.strandby.01@regionh.dk. IN - Ambrus, Rikard. Department of Surgical Gastroenterology, University of Copenhagen, Rigshospitalet, Blegdamsvej 9, DK-2100, Copenhagen-O, Denmark. IN - Secher, Niels H. Department of Anesthesiology, University of Copenhagen, Rigshospitalet, Blegdamsvej 9, Copenhagen-O, DK-2100, Denmark. IN - Goetze, Jens Peter. Department of Clinical Biochemistry, University of Copenhagen, Rigshospitalet, Blegdamsvej 9, Copenhagen-O, DK-2100, Denmark. IN - Achiam, Michael Patrick. Department of Surgical Gastroenterology, University of Copenhagen, Rigshospitalet, Blegdamsvej 9, DK-2100, Copenhagen-O, Denmark. IN - Svendsen, Lars Bo. Department of Surgical Gastroenterology, University of Copenhagen, Rigshospitalet, Blegdamsvej 9, DK-2100, Copenhagen-O, Denmark. TI - Plasma pro-atrial natriuretic peptide to estimate fluid balance during open and robot-assisted esophagectomy: a prospective observational study. SO - BMC Anesthesiology. 17(1):20, 2017 Feb 03 AS - BMC anesthesiol.. 17(1):20, 2017 Feb 03 NJ - BMC anesthesiology PI - Journal available in: Electronic PI - Citation processed from: Internet JC - 100968535 IO - BMC Anesthesiol CP - England KW - Abdominal surgery; Central blood volume; Fluid balance; Plasma-atrial natriuretic peptide AB - BACKGROUND: It remains debated how much fluid should be administered during surgery. The atrial natriuretic peptide precursor proANP is released by atrial distension and deviations in plasma proANP are reported associated with perioperative fluid balance. We hypothesized that plasma proANP would decrease when the central blood volume is compromised during the abdominal part of robot-assisted hybrid (RE) esophagectomy and that a positive fluid balance would be required to maintain plasma proANP. AB - METHODS: Patients undergoing RE (n=25) or open (OE; n=25) esophagectomy for gastroesophageal cancer were included consecutively in this prospective observational study. Plasma proANP was determined repetitively during esophagectomy to allow for distinction between the abdominal and thoracic part of the procedure. The RE group was 15degree head up tilted during the abdominal procedure. AB - RESULTS: The blood loss was 250 (150-375) (RE) and 600 ml (390-855) (OE) (p=0.01), but the two groups of patients were provided with a similar positive fluid balance: 1705 (1390-1983) vs. 1528 ml (1316-1834) (p=0.4). However, plasma proANP decreased by 21% (p<0.01) during the abdominal part of RE carried out during moderate head-up tilt, but only by 11% (p=0.01) during OE where the patients were supine. Plasma proANP and fluid balance were correlated in the RE-group (r=0.5 (0.073-0.840), p=0.02) and tended to correlate in the OE group (r=0.4 (-0.045-0.833), p=0.08). AB - CONCLUSION: The results support that plasma proANP decreases when the central blood volume is compromised and suggest that an about 2200 ml surplus administration of crystalloid is required to maintain plasma proANP during esophagectomy. AB - TRIAL REGISTRATION: Clinicaltrials.gov ( NCT02077673 ). Registered retrospectively February 12^th 2014. ES - 1471-2253 IL - 1471-2253 DI - 10.1186/s12871-017-0314-6 DO - https://dx.doi.org/10.1186/s12871-017-0314-6 PT - Journal Article ID - 28159014 [pubmed] ID - 10.1186/s12871-017-0314-6 [doi] ID - 10.1186/s12871-017-0314-6 [pii] ID - PMC5291941 [pmc] PP - epublish PH - 2016/11/07 [received] PH - 2017/01/27 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT02077673 SL - https://clinicaltrials.gov/search/term=NCT02077673 LG - English EP - 20170203 DP - 2017 Feb 03 DC - 20170204 EZ - 2017/02/05 06:00 DA - 2017/02/06 06:00 DT - 2017/02/06 06:00 YR - 2017 RD - 20170221 UP - 20170222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=28159014 <724. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27856385 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Barron KI AU - Lamvu GM AU - Schmidt RC AU - Fisk M AU - Blanton E AU - Patanwala I FA - Barron, Kenneth I FA - Lamvu, Georgine M FA - Schmidt, R Cole FA - Fisk, Matthew FA - Blanton, Emily FA - Patanwala, Insiyyah IN - Barron, Kenneth I. Division of Advanced and Minimally Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology, University of Virginia School of Medicine, Charlottesville, Virgnia. Electronic address: kenneth.barron.md@gmail.com. IN - Lamvu, Georgine M. Department of Obstetrics and Gynecology, University of Central Florida College of Medicine, Orlando, Florida; Division of Surgery, Gynecology Section, Orlando Veterans Affairs Medical Center, Orlando, Florida. IN - Schmidt, R Cole. Department of Obstetrics and Gynecology, Florida Hospital Graduate Medical Education, Florida Hospital Orlando, Orlando, Florida; Department of Obstetrics and Gynecology, University of Central Florida College of Medicine, Orlando, Florida. IN - Fisk, Matthew. Department of Obstetrics and Gynecology, Florida Hospital Graduate Medical Education, Florida Hospital Orlando, Orlando, Florida; Department of Obstetrics and Gynecology, University of Central Florida College of Medicine, Orlando, Florida. IN - Blanton, Emily. Department of Obstetrics and Gynecology, Florida Hospital Graduate Medical Education, Florida Hospital Orlando, Orlando, Florida; Department of Obstetrics and Gynecology, University of Central Florida College of Medicine, Orlando, Florida. IN - Patanwala, Insiyyah. Department of Obstetrics and Gynecology, Florida Hospital Graduate Medical Education, Florida Hospital Orlando, Orlando, Florida; Department of Obstetrics and Gynecology, University of Central Florida College of Medicine, Orlando, Florida. TI - Wound Infiltration With Extended-Release Versus Short-Acting Bupivacaine Before Laparoscopic Hysterectomy: A Randomized Controlled Trial. SO - Journal of Minimally Invasive Gynecology. 24(2):286-292, 2017 Feb AS - J Minim Invasive Gynecol. 24(2):286-292, 2017 Feb NJ - Journal of minimally invasive gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101235322 IO - J Minim Invasive Gynecol CP - United States KW - Hysterectomy; Laparoscopy; Local anesthesia; Postoperative pain; Robotics AB - STUDY OBJECTIVE: To evaluate if preincision infiltration with extended-release liposomal bupivacaine provides improved overall pain relief compared with 0.25% bupivacaine after laparoscopic or robotic-assisted hysterectomy. AB - DESIGN: A single-center double-masked randomized controlled trial (Canadian Task Force Classification I). AB - SETTING: A tertiary-care community hospital. AB - PATIENTS: Patients recruited from July 2015 through January 2016. Sixty-four patients were randomized, and 59 were analyzed for the primary outcome. AB - INTERVENTIONS: Women scheduled to undergo multiport laparoscopic or robotic-assisted total hysterectomy for benign indications were randomized to receive preincision infiltration with undiluted liposomal bupivacaine or 0.25% bupivacaine. AB - MEASUREMENTS AND MAIN RESULTS: The primary outcome was overall average pain intensity by numeric rating scale (0-10) using the Brief Pain Inventory (BPI) via telephone survey on postoperative day (POD) 3. A sample size of 28 per group (N = 56) was planned to detect a 30% change in pain scores. Secondary outcomes were overall average and worst numeric pain scores on PODs 1, 2, and 14; pain scores in hospital; BPI pain interference scores; and total opioid use. There were no demographic differences between the 2 groups. For the primary outcome, we found a decrease in the average (p = .02) pain scores on POD 3 in the liposomal bupivacaine group. We also found a decrease in worst pain scores on POD 2 (p = .03) and POD 3 (p = .01). There were no differences in pain scores while in the hospital or on POD 1 or POD 14. There were no differences in BPI pain interference scores, opioid use, or reported adverse effects. AB - CONCLUSION: For laparoscopic and robotic-assisted multiport hysterectomies, there is evidence of decreased average postoperative pain with liposomal bupivacaine compared with 0.25% bupivacaine for port-site analgesia on POD 3, but no difference in opioid use or measures of functioning. AB - Copyright Published by Elsevier Inc. ES - 1553-4669 IL - 1553-4650 DI - S1553-4650(16)31161-X DO - https://dx.doi.org/10.1016/j.jmig.2016.11.002 PT - Journal Article ID - 27856385 [pubmed] ID - S1553-4650(16)31161-X [pii] ID - 10.1016/j.jmig.2016.11.002 [doi] PP - ppublish PH - 2016/07/15 [received] PH - 2016/09/25 [revised] PH - 2016/11/05 [accepted] LG - English EP - 20161114 DP - 2017 Feb DC - 20161118 EZ - 2016/11/19 06:00 DA - 2016/11/20 06:00 DT - 2016/11/20 06:00 YR - 2017 RD - 20170206 UP - 20170207 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27856385 <725. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27117120 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Ichihara S AU - Bodin F AU - Pedersen JC AU - Porto de Melo P AU - Garcia JC Jr AU - Facca S AU - Liverneaux PA FA - Ichihara, Satoshi FA - Bodin, Frederic FA - Pedersen, John C FA - Porto de Melo, Paolo FA - Garcia, Jose Carlos Jr FA - Facca, Sybille FA - Liverneaux, Philippe Andre IN - Ichihara, Satoshi. Hand Surgery Department, University of Strasbourg, Strasbourg University Hospitals, FMTS, Icube CNRS 7357, 10, avenue Baumann, 67403 Illkirch, France; Department of Orthopedic Surgery, Juntendo University, Tokyo, Japan. IN - Bodin, Frederic. Plastic Surgery Department, University of Strasbourg, Strasbourg University Hospitals, FMTS, Strasbourg, France. IN - Pedersen, John C. Akron Plastic Surgeons, Akron, OH, USA. IN - Porto de Melo, Paolo. Neurosurgery Department, Sao Paulo Military Area Hospital, Brazilian Army, Sao Paulo, Brazil. IN - Garcia, Jose Carlos Jr. Sports Medicine Division/Shoulder and Elbow Surgery Division, Pontifical Catholic University of Campinas, Sao Paulo, Brazil. IN - Facca, Sybille. Hand Surgery Department, University of Strasbourg, Strasbourg University Hospitals, FMTS, Icube CNRS 7357, 10, avenue Baumann, 67403 Illkirch, France. IN - Liverneaux, Philippe Andre. Hand Surgery Department, University of Strasbourg, Strasbourg University Hospitals, FMTS, Icube CNRS 7357, 10, avenue Baumann, 67403 Illkirch, France. Electronic address: philippe.liverneaux@chru-strasbourg.fr. TI - Robotically assisted harvest of the latissimus dorsi muscle: A cadaver feasibility study and clinical test case. SO - Hand Surgery and Rehabilitation. 35(2):81-4, 2016 Apr AS - Hand Surg Rehabil. 35(2):81-4, 2016 Apr NJ - Hand surgery & rehabilitation PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101681801 IO - Hand Surg Rehabil SB - Index Medicus CP - France KW - Chirurgie robot-assistee; Endoscopic muscle harvest; Latissimus dorsi; Prelevement musculaire endoscopique; Robotic surgery AB - The applications of robotic surgery have quickly spread into a variety of surgical fields. Interest in robotic endoscopic surgery is high because of the small size of the incisions, cosmetic advantages, less invasive surgical techniques, decreased scar tissue, shorter duration of hospitalization and increased cost-effectiveness. We will describe an anatomical feasibility study and a clinical test case of robotically assisted pedicled transposition of the latissimus dorsi muscle. AB - Copyright © 2016 SFCM. Published by Elsevier Masson SAS. All rights reserved. ES - 2468-1210 IL - 2468-1210 DI - S2468-1229(16)00026-8 DO - https://dx.doi.org/10.1016/j.hansur.2016.01.002 DO - https://dx.doi.org/ 10.1111/mec.13956 PT - Journal Article ID - 28130942 [pubmed] ID - 10.1111/mec.13956 [doi] PP - ppublish LG - English EP - 20160218 DP - 2016 Apr DC - 20160427 EZ - 2017/ 01/ 29 06: 00 YR - 2016 RD - 20170127 UP - 20170130 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27117120 <726. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27402095 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Chen S AU - Zhan Q AU - Jin JB AU - Wu ZC AU - Shi Y AU - Cheng DF AU - Chen H AU - Deng XX AU - Shen BY AU - Peng CH AU - Li HW FA - Chen, Shi FA - Zhan, Qian FA - Jin, Jia-Bin FA - Wu, Zhi-Chong FA - Shi, Yuan FA - Cheng, Dong-Feng FA - Chen, Hao FA - Deng, Xia-Xing FA - Shen, Bai-Yong FA - Peng, Cheng-Hong FA - Li, Hong-Wei IN - Chen, Shi. Department of General Surgery, Research Institute of Pancreatic Disease, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Chen, Shi. Department of Hepatobiliary Surgery, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, People's Republic of China. IN - Zhan, Qian. Department of General Surgery, Research Institute of Pancreatic Disease, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Zhan, Qian. Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Jin, Jia-Bin. Department of General Surgery, Research Institute of Pancreatic Disease, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Jin, Jia-Bin. Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Wu, Zhi-Chong. Department of General Surgery, Research Institute of Pancreatic Disease, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Wu, Zhi-Chong. Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Shi, Yuan. Department of General Surgery, Research Institute of Pancreatic Disease, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Shi, Yuan. Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Cheng, Dong-Feng. Department of General Surgery, Research Institute of Pancreatic Disease, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Cheng, Dong-Feng. Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Chen, Hao. Department of General Surgery, Research Institute of Pancreatic Disease, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Chen, Hao. Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Deng, Xia-Xing. Department of General Surgery, Research Institute of Pancreatic Disease, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Deng, Xia-Xing. Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Shen, Bai-Yong. Department of General Surgery, Research Institute of Pancreatic Disease, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. ruijinsby@hotmail.com. IN - Shen, Bai-Yong. Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. ruijinsby@hotmail.com. IN - Peng, Cheng-Hong. Department of General Surgery, Research Institute of Pancreatic Disease, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. chhpeng@yeah.net. IN - Peng, Cheng-Hong. Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. chhpeng@yeah.net. IN - Li, Hong-Wei. Department of General Surgery, Research Institute of Pancreatic Disease, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. IN - Li, Hong-Wei. Shanghai Institute of Digestive Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China. TI - Robot-assisted laparoscopic versus open middle pancreatectomy: short-term results of a randomized controlled trial. SO - Surgical Endoscopy. 31(2):962-971, 2017 Feb AS - Surg Endosc. 31(2):962-971, 2017 Feb NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc CP - Germany KW - Length of hospital stay; Middle pancreatectomy; Postoperative pancreatic fistula; Randomized; Robot-assisted laparoscopy AB - OBJECTIVE: This first prospective randomized controlled trial was performed to compare short-term outcomes of robot-assisted laparoscopic middle pancreatectomy (RA-MP) with open middle pancreatectomy (OMP). AB - BACKGROUND: RA-MP is a novel minimally invasive surgical technique for benign or borderline tumors in the pancreatic neck or body. Its short-term effectiveness and safety remain unknown, compared to OMP. AB - METHODS: Patients eligible for MP from August 2011 to November 2015 were randomized into the RA-MP or OMP group. The primary endpoint was length of hospital stay (LOS). Secondary endpoints were intraoperative parameters, and postoperative and recovery variables. AB - RESULTS: A total of 100 patients were included into the study to analyze primary and secondary endpoints. Demographic characteristics and pathological parameters were similar in both groups. Furthermore, LOS was significantly shorter (15.6 vs. 21.7 days, P = 0.002), median operative time was reduced (160 vs. 193 min, P = 0.002), median blood loss was lower (50 vs. 200 mL, P < 0.001), rate of clinical postoperative pancreatic fistula (POPF) was lower (18 vs. 36.0 %, P = 0.043), nutritional status recovery was better, off-bed return to activity was expedited (3.1 vs. 4.6 days, P < 0.001), and resumption of bowel movement was faster (3.5 vs. 5.0 days, P < 0.001) in the RA-MP group, compared to the OMP group. AB - CONCLUSION: RA-MP was associated with significantly shorter LOS, reduced operative time, blood loss and clinical POPF rate, and expedited postoperative recovery, compared to OMP. ES - 1432-2218 IL - 0930-2794 DI - 10.1007/s00464-016-5046-z DO - https://dx.doi.org/10.1007/s00464-016-5046-z PT - Journal Article ID - 27402095 [pubmed] ID - 10.1007/s00464-016-5046-z [doi] ID - 10.1007/s00464-016-5046-z [pii] PP - ppublish PH - 2016/02/24 [received] PH - 2016/06/11 [accepted] LG - English EP - 20160711 DP - 2017 Feb DC - 20160712 EZ - 2016/07/13 06:00 DA - 2016/07/13 06:00 DT - 2016/07/13 06:00 YR - 2017 RD - 20170126 UP - 20170127 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27402095 <727. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27743071 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Salloum C AU - Lim C AU - Lahat E AU - Gavara CG AU - Levesque E AU - Compagnon P AU - Azoulay D FA - Salloum, Chady FA - Lim, Chetana FA - Lahat, Eylon FA - Gavara, Concepcion Gomez I FA - Levesque, Eric FA - Compagnon, Philippe FA - Azoulay, Daniel IN - Salloum, Chady. Department of Hepato-Biliary and Pancreatic Surgery and Liver Transplantation, AP-HP Henri Mondor Hospital, 51 Avenue De Lattre De Tassigny, 94010, Creteil, France. IN - Lim, Chetana. Department of Hepato-Biliary and Pancreatic Surgery and Liver Transplantation, AP-HP Henri Mondor Hospital, 51 Avenue De Lattre De Tassigny, 94010, Creteil, France. IN - Lahat, Eylon. Department of Hepato-Biliary and Pancreatic Surgery and Liver Transplantation, AP-HP Henri Mondor Hospital, 51 Avenue De Lattre De Tassigny, 94010, Creteil, France. IN - Gavara, Concepcion Gomez I. Department of Hepato-Biliary and Pancreatic Surgery and Liver Transplantation, AP-HP Henri Mondor Hospital, 51 Avenue De Lattre De Tassigny, 94010, Creteil, France. IN - Levesque, Eric. Department of Anesthesia and Liver Intensive Care Unit, AP-HP Henri Mondor Hospital, Creteil, France. IN - Compagnon, Philippe. Department of Hepato-Biliary and Pancreatic Surgery and Liver Transplantation, AP-HP Henri Mondor Hospital, 51 Avenue De Lattre De Tassigny, 94010, Creteil, France. IN - Compagnon, Philippe. INSERM 955, Creteil, France. IN - Azoulay, Daniel. Department of Hepato-Biliary and Pancreatic Surgery and Liver Transplantation, AP-HP Henri Mondor Hospital, 51 Avenue De Lattre De Tassigny, 94010, Creteil, France. daniel.azoulay@hmn.aphp.fr. IN - Azoulay, Daniel. INSERM 955, Creteil, France. daniel.azoulay@hmn.aphp.fr. TI - Robotic-Assisted Versus Laparoscopic Left Lateral Sectionectomy: Analysis of Surgical Outcomes and Costs by a Propensity Score Matched Cohort Study. SO - World Journal of Surgery. 41(2):516-524, 2017 Feb AS - World J Surg. 41(2):516-524, 2017 Feb NJ - World journal of surgery PI - Journal available in: Print PI - Citation processed from: Internet JC - xo8, 7704052 IO - World J Surg CP - United States AB - BACKGROUND: After comparing with open approach, left lateral sectionectomy (LLS) has become standard in terms of short-term outcomes without jeopardizing long-term survival when performed for malignancy. The aim of this study was to compare the short-term and economic outcomes of laparoscopic (L-LLS) and robotic (R-LLS) LLS. AB - METHODS: All consecutive patients who underwent L-LLS or R-LLS from 1997 to 2014 were analyzed. Short-term and economic outcomes were compared between the two groups using a propensity score matching (PSM). AB - RESULTS: Ninety-six consecutive cases of LLS were performed using the laparoscopic (80 cases; 83 %) or robotic (16 cases; 17 %) approach. The two groups were similar for operative and surgical outcomes. Operation time was similar in the R-LLS compared to the L-LLS group (190 vs. 162 min; p = 0.10). Perioperative costs were higher (1457 vs. 576 ; p < 0.0001) in the R-LLS group than in the L-LLS group; however, postoperative costs were similar between the two groups (4065 in the R-LLS group vs. 5459 in the L-LLS group; p = 0.30). Total costs were similar between the two groups (5522 in the R-LLS group vs. 6035 in the L-LLS group; p = 0.70). The PSM included 14 patients for each group. Surgical and economic outcomes remained similar after PSM, except for total operating time which was significantly longer in the R-LLS group than in the L-LLS group. AB - CONCLUSIONS: Even if feasible and safe, the robotic approach does not seem so far to offer additional benefit in terms of intra- and postoperative outcomes over the laparoscopic approach in patients requiring LLS. Total costs associated with the R-LLS group are not greater than that associated with the L-LLS group, which is the standard of care so far. ES - 1432-2323 IL - 0364-2313 DI - 10.1007/s00268-016-3736-2 DO - https://dx.doi.org/10.1007/s00268-016-3736-2 PT - Journal Article ID - 27743071 [pubmed] ID - 10.1007/s00268-016-3736-2 [doi] ID - 10.1007/s00268-016-3736-2 [pii] PP - ppublish LG - English DP - 2017 Feb DC - 20161015 EZ - 2016/10/16 06:00 DA - 2016/10/16 06:00 DT - 2016/10/16 06:00 YR - 2017 RD - 20170124 UP - 20170125 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27743071 <728. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27616721 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Fossati N AU - Wiklund P AU - Rochat CH AU - Montorsi F AU - Dasgupta P AU - Sanchez-Salas R AU - Canda AE AU - Piechaud T AU - Artibani W AU - Mottrie A FA - Fossati, Nicola FA - Wiklund, Peter FA - Rochat, Charles-Henry FA - Montorsi, Francesco FA - Dasgupta, Prokar FA - Sanchez-Salas, Rafael FA - Canda, Abdullah E FA - Piechaud, Thierry FA - Artibani, Walter FA - Mottrie, Alexandre IN - Fossati, Nicola. EAU Robotic Urology Section, European Association of Urology, Arnhem, The Netherlands; Division of Oncology/Unit of Urology, IRCCS Ospedale San Raffaele, Milan, Italy. IN - Wiklund, Peter. EAU Robotic Urology Section, European Association of Urology, Arnhem, The Netherlands; Department of Urology, Karolinska University Hospital, Stockholm, Sweden. IN - Rochat, Charles-Henry. EAU Robotic Urology Section, European Association of Urology, Arnhem, The Netherlands; Urology Department, Clinique Generale Beaulieu, Geneva, Switzerland. IN - Montorsi, Francesco. EAU Robotic Urology Section, European Association of Urology, Arnhem, The Netherlands; Division of Oncology/Unit of Urology, IRCCS Ospedale San Raffaele, Milan, Italy. IN - Dasgupta, Prokar. EAU Robotic Urology Section, European Association of Urology, Arnhem, The Netherlands; Department of Urology, Guys Hospital, London, UK. IN - Sanchez-Salas, Rafael. EAU Robotic Urology Section, European Association of Urology, Arnhem, The Netherlands; Department of Urology, L'Institut Mutualiste Montsouris, Paris, France. IN - Canda, Abdullah E. EAU Robotic Urology Section, European Association of Urology, Arnhem, The Netherlands; Department of Urology, Ankara Ataturk Hospital, Ankara, Turkey. IN - Piechaud, Thierry. EAU Robotic Urology Section, European Association of Urology, Arnhem, The Netherlands; Clinique Saint Augustin, Bordeaux, France. IN - Artibani, Walter. EAU Robotic Urology Section, European Association of Urology, Arnhem, The Netherlands; Department of Urology, Verona University Hospital, Verona, Italy. IN - Mottrie, Alexandre. EAU Robotic Urology Section, European Association of Urology, Arnhem, The Netherlands; Department of Urology, O.L.V. Clinic, Aalst, Belgium. Electronic address: alex.mottrie@orsi.be. TI - Robotic and Open Radical Prostatectomy: The First Prospective Randomised Controlled Trial Fuels Debate Rather than Closing the Question. SO - European Urology. 71(3):307-308, 2017 Mar AS - Eur Urol. 71(3):307-308, 2017 Mar NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. CP - Switzerland AB - Despite the finally acquired level 1 evidence, the urologic debate on open versus robotic prostatectomy still persists. This trial from Brisbane will encourage future studies that will better inform this debate and define what robotic surgery offers. AB - Copyright © 2016 European Association of Urology. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(16)30580-2 DO - https://dx.doi.org/10.1016/j.eururo.2016.08.068 PT - Editorial ID - 27616721 [pubmed] ID - S0302-2838(16)30580-2 [pii] ID - 10.1016/j.eururo.2016.08.068 [doi] PP - ppublish PH - 2016/08/24 [received] PH - 2016/08/31 [accepted] LG - English EP - 20160913 DP - 2017 Mar DC - 20160912 EZ - 2016/09/13 06:00 DA - 2016/10/23 06:00 DT - 2016/10/23 06:00 YR - 2017 RD - 20170122 UP - 20170124 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27616721 <729. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28100529 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Marechal C AU - Berthiller J AU - Tosetti S AU - Cogniat B AU - Desombres H AU - Bouvet L AU - Kassai B AU - Chassard D AU - de Queiroz Siqueira M FA - Marechal, C FA - Berthiller, J FA - Tosetti, S FA - Cogniat, B FA - Desombres, H FA - Bouvet, L FA - Kassai, B FA - Chassard, D FA - de Queiroz Siqueira, M IN - Marechal, C. Department of Anaesthesiology, Hopital Femme Mere Enfant, Bron F-69677, France. IN - Marechal, C. University Lyon 1, Lyon F-69000, France. IN - Berthiller, J. Service de Pharmacologie Clinique, EPICIME-CIC 1407 de Lyon, Inserm, CHU-Lyon, Bron F-69677, France. IN - Tosetti, S. Department of Anaesthesiology, Hopital Femme Mere Enfant, Bron F-69677, France. IN - Cogniat, B. Department of Anaesthesiology, Hopital Femme Mere Enfant, Bron F-69677, France. IN - Desombres, H. Department of Child and Adolescent Psychiatry, Hopital Femme Mere Enfant, Bron F-69677, France. IN - Desombres, H. University Lyon 1, Lyon F-69000, France. IN - Bouvet, L. Department of Anaesthesiology, Hopital Femme Mere Enfant, Bron F-69677, France. IN - Bouvet, L. University Lyon 1, Lyon F-69000, France. IN - Kassai, B. University Lyon 1, Lyon F-69000, France. IN - Kassai, B. Service de Pharmacologie Clinique, EPICIME-CIC 1407 de Lyon, Inserm, CHU-Lyon, Bron F-69677, France. IN - Chassard, D. Department of Anaesthesiology, Hopital Femme Mere Enfant, Bron F-69677, France dominique.chassard@chu-lyon.fr. IN - Chassard, D. University Lyon 1, Lyon F-69000, France. IN - de Queiroz Siqueira, M. Department of Anaesthesiology, Hopital Femme Mere Enfant, Bron F-69677, France. TI - Children and parental anxiolysis in paediatric ambulatory surgery: a randomized controlled study comparing 0.3mg kg-1 midazolam to tablet computer based interactive distraction. SO - British Journal of Anaesthesia. 118(2):247-253, 2017 Feb AS - Br J Anaesth. 118(2):247-253, 2017 Feb NJ - British journal of anaesthesia PI - Journal available in: Print PI - Citation processed from: Internet JC - 0372541 IO - Br J Anaesth CP - England KW - ambulatory surgical procedures; child; premedication AB - BACKGROUND: The operating theatre, anaesthesia induction and separation from parents create fear and anxiety in children. Anxiety leads to adverse behavioral changes appearing and sometimes persisting during the postoperative period. Our aim was to compare the effects of midazolam (0.3mg kg^-1: MDZ) for premedication with age-appropriate tablet game apps (TAB) on children anxiety during and after ambulatory surgery. AB - METHODS: A randomized controlled trial was conducted from May 16th, 2013 to March 25th, 2014 at the Children Hospital of Lyon. The primary outcome of this study was the change in m-YPAS score at the time of anaesthetic mask induction. Anxiety was also assessed in the waiting surgical area, at the time of separation with parents and when back in the ambulatory surgery ward. AB - RESULTS: One hundred and eighteen patients aged four-11yr were recruited, 60 in the TAB Group and 58 in the MDZ Group. Main endpoint was missing for three patients from the MDZ Group. At the time of mask induction, there was no significant difference between MDZ and TAB Group for the m-YPAS score (40.5 (18.6) vs 41.8 (20.7), P=0.99). There was no significant correlation between m-YPAS score and its evolution over the four period of time between subjects. AB - CONCLUSIONS: We were not able to show whether TAB is superior to MDZ to blunt anxiety in children undergoing ambulatory surgery. TAB is a non-pharmacological tool which has the capacity in reducing perioperative stress without any sedative effect in this population. AB - CLINICAL TRIAL REGISTRATION: NCT 02192710. AB - Copyright © The Author 2017. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com. ES - 1471-6771 IL - 0007-0912 DI - aew436 DO - https://dx.doi.org/10.1093/bja/aew436 PT - Journal Article ID - 28100529 [pubmed] ID - aew436 [pii] ID - 10.1093/bja/aew436 [doi] PP - ppublish PH - 2016/12/07 [accepted] LG - English DP - 2017 Feb DC - 20170119 EZ - 2017/01/20 06:00 DA - 2017/01/20 06:00 DT - 2017/01/20 06:00 YR - 2017 RD - 20170119 UP - 20170120 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=28100529 <730. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27693447 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Nguyen HG AU - Punnen S AU - Cowan JE AU - Leapman M AU - Cary C AU - Welty C AU - Weinberg V AU - Cooperberg MR AU - Meng MV AU - Greene KL AU - Garcia M AU - Carroll PR FA - Nguyen, Hao G FA - Punnen, Sanoj FA - Cowan, Janet E FA - Leapman, Michael FA - Cary, Clint FA - Welty, Christopher FA - Weinberg, Vivian FA - Cooperberg, Matthew R FA - Meng, Maxwell V FA - Greene, Kirsten L FA - Garcia, Maurice FA - Carroll, Peter R IN - Nguyen, Hao G. Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California-San Francisco, San Francisco, California. Electronic address: hao.nguyen@ucsf.edu. IN - Punnen, Sanoj. Department of Urology, Miller School of Medicine and Sylvester Cancer Center, University of Miami, Miami, Florida. IN - Cowan, Janet E. Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California-San Francisco, San Francisco, California. IN - Leapman, Michael. Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California-San Francisco, San Francisco, California. IN - Cary, Clint. Department of Urology, Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, Indiana. IN - Welty, Christopher. Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California-San Francisco, San Francisco, California. IN - Weinberg, Vivian. Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California-San Francisco, San Francisco, California. IN - Cooperberg, Matthew R. Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California-San Francisco, San Francisco, California. IN - Meng, Maxwell V. Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California-San Francisco, San Francisco, California. IN - Greene, Kirsten L. Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California-San Francisco, San Francisco, California. IN - Garcia, Maurice. Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California-San Francisco, San Francisco, California. IN - Carroll, Peter R. Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California-San Francisco, San Francisco, California. Electronic address: peter.carroll@ucsf.edu. TI - A Randomized Study of Intraoperative Autologous Retropubic Urethral Sling on Urinary Control after Robotic Assisted Radical Prostatectomy. SO - Journal of Urology. 197(2):369-375, 2017 Feb AS - J Urol. 197(2):369-375, 2017 Feb NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. CP - United States KW - prostatectomy; prostatic neoplasms; robotics; stress incontinence; suburethral slings; urinary AB - PURPOSE: We evaluated whether placement of a retropubic urethral sling fashioned from autologous vas deferens during robotic assisted radical prostatectomy would improve recovery of continence. AB - MATERIALS AND METHODS: In a phase 2, single blind trial age stratified patients were randomized to undergo robotic assisted radical prostatectomy by multiple surgeons with or without sling placement. The outcomes were complete continence (0 urinary pads of any type) and near continence (0, an occasional or 1 pad per day) at 6 months, which was assessed by the Fisher exact test and logistic regression. The Kaplan-Meier method and the log rank test were used to evaluate time to continence. EPIC-UIN (Expanded Prostate Cancer Index Composite-Urinary Inventory) and I-PSS (International Prostate Symptom Score) 1, 3 and 6 months after catheter removal were evaluated by mixed models for repeated measures. AB - RESULTS: Of 203 patients who were recruited 95 and 100 were randomized to undergo sling and no sling placement, respectively, and completed postoperative interviews. Six months after surgery the proportions reporting complete and near continence (66% and 87%, respectively) and times to complete and near continence were similar in the groups. Younger age was associated with a higher likelihood of complete continence (OR 1.74 per decreasing 5-year interval, 95% CI 1.23-2.48, p <0.01) and near continence (OR 2.18 per decreasing 5-year interval, 95% CI 1.21-3.92, p <0.01) adjusting for clinical, urinary and surgical factors. Adjusted EPIC-UIN and I-PSS scores changed with time but did not differ between the groups. No serious adverse events were observed. AB - CONCLUSIONS: This trial failed to demonstrate a benefit of autologous urethral sling placement at robotic assisted radical prostatectomy on early return of continence at 6 months. Continence was related to patient age in adjusted models. AB - Copyright © 2017 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(16)31400-8 DO - https://dx.doi.org/10.1016/j.juro.2016.08.122 PT - Journal Article ID - 27693447 [pubmed] ID - S0022-5347(16)31400-8 [pii] ID - 10.1016/j.juro.2016.08.122 [doi] PP - ppublish PH - 2016/08/17 [accepted] LG - English EP - 20160928 DP - 2017 Feb DC - 20161003 EZ - 2016/10/04 06:00 DA - 2016/10/04 06:00 DT - 2016/10/04 06:00 YR - 2017 RD - 20170117 UP - 20170118 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27693447 <731. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27575538 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Process AU - Jain P AU - Rajaram S AU - Gupta B AU - Goel N AU - Srivastava H FA - Jain, Prachi FA - Rajaram, Shalini FA - Gupta, Bindiya FA - Goel, Neerja FA - Srivastava, Himsweta IN - Jain, Prachi. Department of Obstetrics and Gynecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India. Electronic address: drprachijain85@gmail.com. IN - Rajaram, Shalini. Department of Obstetrics and Gynecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India. IN - Gupta, Bindiya. Department of Obstetrics and Gynecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India. IN - Goel, Neerja. Department of Obstetrics and Gynecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India. IN - Srivastava, Himsweta. Department of Obstetrics and Gynecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India. TI - Randomized controlled trial of thermal balloon ablation versus vaginal hysterectomy for leiomyoma-induced heavy menstrual bleeding. SO - International Journal of Gynaecology & Obstetrics. 135(2):140-144, 2016 Nov AS - Int J Gynaecol Obstet. 135(2):140-144, 2016 Nov NJ - International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - e4t, 0210174 IO - Int J Gynaecol Obstet CP - United States KW - Abnormal uterine bleeding; Fibroid uterus; Heavy menstrual bleeding; Hysterectomy; Thermal balloon ablation; Uterine leiomyoma; Vaginal hysterectomy AB - OBJECTIVE: To compare the efficacy of thermal balloon ablation (TBA) with that of vaginal hysterectomy in the treatment of leiomyoma-induced heavy menstrual bleeding (HMB). AB - METHODS: An open-label randomized controlled trial was conducted between November 1, 2012, and October 31, 2014, in a tertiary care hospital in Delhi, India. Eligible women with HMB (aged >40 years, uterus size <14 weeks of pregnancy, leiomyoma <5 cm, uterocervical length <12 cm) were randomly assigned (1:1) to undergo TBA or vaginal hysterectomy using computer-generated random number tables. The primary outcome was the number of women in the TBA group with HMB 6 months after surgery. Analyses were by intention to treat. AB - RESULTS: Each group contained 20 women. No women in the TBA group had HMB at 6 months. Nineteen women were amenorrheic by 6 months and one was hypomenorrheic. AB - CONCLUSION: TBA can replace vaginal hysterectomy in some perimenopausal women with uterine leiomyomas. Clinical Trials Registry India: CTRI/2016/07/007119. AB - Copyright © 2016 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved. ES - 1879-3479 IL - 0020-7292 DI - S0020-7292(16)30271-5 DO - https://dx.doi.org/10.1016/j.ijgo.2016.04.020 PT - Journal Article ID - 27575538 [pubmed] ID - S0020-7292(16)30271-5 [pii] ID - 10.1016/j.ijgo.2016.04.020 [doi] PP - ppublish PH - 2016/01/10 [received] PH - 2016/04/15 [revised] PH - 2016/07/27 [accepted] LG - English EP - 20160805 DP - 2016 Nov DC - 20160830 EZ - 2016/08/31 06:00 DA - 2016/08/31 06:00 DT - 2016/08/31 06:00 YR - 2016 RD - 20161229 UP - 20161230 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27575538 <732. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27544575 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Grande P AU - Di Pierro GB AU - Mordasini L AU - Ferrari M AU - Wurnschimmel C AU - Danuser H AU - Mattei A FA - Grande, Pietro FA - Di Pierro, Giovanni Battista FA - Mordasini, Livio FA - Ferrari, Matteo FA - Wurnschimmel, Christoph FA - Danuser, Hansjorg FA - Mattei, Agostino IN - Grande, Pietro. Klinik fur Urologie, Luzerner Kantonsspital, Lucerne, Switzerland. IN - Di Pierro, Giovanni Battista. Klinik fur Urologie, Luzerner Kantonsspital, Lucerne, Switzerland. IN - Mordasini, Livio. Klinik fur Urologie, Luzerner Kantonsspital, Lucerne, Switzerland. IN - Ferrari, Matteo. Klinik fur Urologie, Luzerner Kantonsspital, Lucerne, Switzerland. IN - Wurnschimmel, Christoph. Klinik fur Urologie, Luzerner Kantonsspital, Lucerne, Switzerland. IN - Danuser, Hansjorg. Klinik fur Urologie, Luzerner Kantonsspital, Lucerne, Switzerland. IN - Mattei, Agostino. Klinik fur Urologie, Luzerner Kantonsspital, Lucerne, Switzerland. Electronic address: agostino.mattei@luks.ch. TI - Prospective Randomized Trial Comparing Titanium Clips to Bipolar Coagulation in Sealing Lymphatic Vessels During Pelvic Lymph Node Dissection at the Time of Robot-assisted Radical Prostatectomy. SO - European Urology. 71(2):155-158, 2017 Feb AS - Eur Urol. 71(2):155-158, 2017 Feb NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. CP - Switzerland KW - Complications; Lymph node dissection; Lymphocele; Prostate cancer; Robot-assisted AB - Lymphocele is the most common complication after pelvic lymph node dissection (PLND). Over the years, various techniques have been introduced to prevent lymphocele, but no final conclusion can be drawn regarding the superiority of one technique over another. In this prospective study, 220 patients undergoing robot-assisted radical prostatectomy between 2012 and 2015 were randomized to receive titanium clips (group A, n=110) or bipolar coagulation (group B, n=110) to seal lymphatic vessels at the level of the femoral canal during extended PLND (ePLND). Ultrasound examination was used to detect lymphoceles at 10 and 90 d after surgery. Lymphocele was defined as any clearly definable fluid collection and was considered clinically significant when requiring treatment. There were no statistically significant differences between groups A and B regarding overall lymphocele incidence (47% vs 48%; difference -0.91%, 95% confidence interval [CI] -2.6 to 0.7; p=0.9) and the rate of clinically significant lymphocele [5% vs 4%; difference 0.75%, 95% CI, 0.1-3.2; p=0.7]. The two groups were comparable regarding mean (+/-SD) lymphocele volume (30+/-32 vs 35+/-39ml; p=0.6), lymphocele location (unilateral, 37% vs 35%, p=0.7; bilateral, 13% vs 14%, p=0.9), and time to lymphocele diagnosis (95% vs 98% on postoperative day 10; p=0.5). In conclusion, this trial failed to identify a difference in lymphocele occurrence between clipping and coagulation of the lymphatic vessels at the level of the femoral canal during robot-assisted ePLND for prostate cancer. AB - PATIENT SUMMARY: In this study we compared the frequency of postoperative complications after sealing lymphatic vessels from the leg to the abdomen using metallic clips or electrical coagulation during robot-assisted surgery for prostate cancer. We found no difference in postoperative complications between the two methods. AB - Copyright © 2016 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(16)30473-0 DO - https://dx.doi.org/ 10.1016/j.eururo.2016.08.006 PT - Journal Article ID - 27544575 [pubmed] ID - S0302-2838(16)30473-0 [pii] ID - 10.1016/j.eururo.2016.08.006 [doi] PP - ppublish PH - 2016/ 04/ 15 [received] PH - 2016/ 08/ 03 [accepted] LG - English EP - 2016 08 17 DP - 2017 Feb DC - 2016 08 21 EZ - 2016/ 08/ 22 06: 00 DA - 2016/ 08/ 22 06: 00 DT - 2016/ 08/ 22 06: 00 YR - 2017 UP - 20161229 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27544575 <733. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27362908 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Cohen SL AU - Senapati S AU - Gargiulo AR AU - Srouji SS AU - Tu FF AU - Solnik J AU - Hur HC AU - Vitonis A AU - Jonsdottir GM AU - Wang KC AU - Einarsson JI FA - Cohen, S L FA - Senapati, S FA - Gargiulo, A R FA - Srouji, S S FA - Tu, F F FA - Solnik, J FA - Hur, H-C FA - Vitonis, A FA - Jonsdottir, G M FA - Wang, K C FA - Einarsson, J I IN - Cohen, S L. Division of Minimally Invasive Gynecologic Surgery, Brigham and Women's Hospital, Boston, MA, USA. IN - Senapati, S. Division of Gynecological Pain and Minimally Invasive Surgery, NorthShore University HealthSystem, Evanston IL & Pritzker School of Medicine, University of Chicago, Chicago, IL, USA. IN - Gargiulo, A R. Division of Reproductive Endocrinology and Infertility, Brigham and Women's Hospital, Boston, MA, USA. IN - Srouji, S S. Division of Reproductive Endocrinology and Infertility, Brigham and Women's Hospital, Boston, MA, USA. IN - Tu, F F. Division of Gynecological Pain and Minimally Invasive Surgery, NorthShore University HealthSystem, Evanston IL & Pritzker School of Medicine, University of Chicago, Chicago, IL, USA. IN - Solnik, J. Cedars Sinai Medical Center, Los Angeles, CA, USA. IN - Hur, H-C. Beth Israel Deaconess Medical Center, Boston, MA, USA. IN - Vitonis, A. Division of Minimally Invasive Gynecologic Surgery, Brigham and Women's Hospital, Boston, MA, USA. IN - Jonsdottir, G M. Division of Minimally Invasive Gynecologic Surgery, Brigham and Women's Hospital, Boston, MA, USA. IN - Wang, K C. Division of Minimally Invasive Gynecologic Surgery, Brigham and Women's Hospital, Boston, MA, USA. IN - Einarsson, J I. Division of Minimally Invasive Gynecologic Surgery, Brigham and Women's Hospital, Boston, MA, USA. TI - Dilute versus concentrated vasopressin administration during laparoscopic myomectomy: a randomised controlled trial. SO - BJOG: An International Journal of Obstetrics & Gynaecology. 124(2):262-268, 2017 Jan AS - BJOG. 124(2):262-268, 2017 Jan NJ - BJOG : an international journal of obstetrics and gynaecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 100935741 IO - BJOG CP - England KW - Blood loss; myomectomy; vasopressin AB - OBJECTIVE: To determine if higher-volume, fixed-dose administration of vasopressin further reduces blood loss at the time of minimally invasive myomectomy. AB - DESIGN: Randomised multicentre clinical trial. AB - SETTING: Tertiary-care academic centres in the USA. AB - POPULATION: Women undergoing conventional laparoscopic or robot-assisted laparoscopic myomectomy. AB - METHODS: All participants received the same 10-unit (U) dose of vasopressin, but were randomly assigned to one of two groups: (i) received 200 ml of diluted vasopressin solution (20 U in 400 ml normal saline), and (ii) received 30 ml of concentrated vasopressin solution (20 U in 60 ml normal saline). AB - MAIN OUTCOME MEASURES: The primary study outcome was estimated blood loss; the study was powered to detect a 100-ml difference. AB - RESULTS: A total of 152 women were randomised; 76 patients in each group. Baseline demographics were similar between groups. The primary outcome of intraoperative blood loss was not significantly different, as measured by three parameters: surgeon estimate (mean estimated blood loss 178 +/- 265 ml and 198 +/- 232 ml, dilute and concentrated groups respectively, P = 0.65), suction canister-calculated blood loss, or change in haematocrit levels. There were no vasopressin-related adverse events. AB - CONCLUSION: Both dilute and concentrated vasopressin solutions that use the same drug dosing demonstrate comparable safety and tolerability when administered for minimally invasive myomectomy; however, higher volume administration of vasopressin does not reduce blood loss. AB - TWEETABLE ABSTRACT: This randomised trial failed to show benefit of high-volume dilute vasopression. AB - Copyright © 2016 Royal College of Obstetricians and Gynaecologists. ES - 1471-0528 IL - 1470-0328 DO - https://dx.doi.org/10.1111/1471-0528.14179 PT - Journal Article ID - 27362908 [pubmed] ID - 10.1111/1471-0528.14179 [doi] PP - ppublish PH - 2016/05/17 [accepted] LG - English EP - 20160630 DP - 2017 Jan DC - 20160711 EZ - 2016/07/01 06:00 DA - 2016/07/01 06:00 DT - 2016/07/01 06:00 YR - 2017 RD - 20161224 UP - 20161227 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27362908 <734. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27262849 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Process AU - Takagi T AU - Kondo T AU - Tachibana H AU - Iizuka J AU - Omae K AU - Kobayashi H AU - Yoshida K AU - Hashimoto Y AU - Tanabe K FA - Takagi, Toshio FA - Kondo, Tsunenori FA - Tachibana, Hidekazu FA - Iizuka, Junpei FA - Omae, Kenji FA - Kobayashi, Hirohito FA - Yoshida, Kazuhiko FA - Hashimoto, Yasunobu FA - Tanabe, Kazunari IN - Takagi, Toshio. Department of Urology, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan. t.takagi1192@gmail.com. IN - Kondo, Tsunenori. Department of Urology, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan. IN - Tachibana, Hidekazu. Department of Urology, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan. IN - Iizuka, Junpei. Department of Urology, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan. IN - Omae, Kenji. Department of Urology, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan. IN - Kobayashi, Hirohito. Department of Urology, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan. IN - Yoshida, Kazuhiko. Department of Urology, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan. IN - Hashimoto, Yasunobu. Department of Urology, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan. IN - Tanabe, Kazunari. Department of Urology, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan. TI - A propensity score-matched comparison of surgical precision obtained by using volumetric analysis between robot-assisted laparoscopic and open partial nephrectomy for T1 renal cell carcinoma: a retrospective non-randomized observational study of initial outcomes. SO - International Urology & Nephrology. 48(10):1585-91, 2016 Oct AS - Int Urol Nephrol. 48(10):1585-91, 2016 Oct NJ - International urology and nephrology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - guq, 0262521 IO - Int Urol Nephrol SB - Index Medicus CP - Netherlands KW - Kidney neoplasm; Nephrectomy; Propensity score; Robotic surgical procedures AB - PURPOSE: We compared surgical outcomes between robot-assisted laparoscopic partial nephrectomy (RAPN) and open partial nephrectomy (OPN) by using volumetric analysis in a propensity score-matched analysis. AB - METHODS: We analyzed the records of 279 patients with normal contralateral kidneys who underwent RAPN or OPN for T1 renal tumors between 2012 and 2014. Volumetric studies to assess the vascularized parenchymal volume of the operated kidney were performed 2 months preoperatively and 6 months postoperatively. Patient data, including age, body mass index, presence of hypertension and/or diabetes mellitus, American Society of Anesthesiologists score, tumor size, preoperative estimated glomerular filtration rate, and tumor complexity using the renal nephrometry score, were matched 1:1 using propensity score matching between groups. AB - RESULTS: This cohort included 100 patients who underwent RAPN and 179 who underwent OPN. After matching, 48 patients were included in each group. Mean tumor diameter was 31 mm, and about 14 % were high-complexity tumors (RENAL score 10-12). The RAPN and OPN groups showed no significant differences in the rate of preservation of global renal function (95 vs. 92 %) and parenchymal volume of the operated kidney (84 vs. 79 %). Similarly, urological complications did not significantly differ between groups. Surgical margins were negative in all tumors. Patients who underwent RAPN had lower estimated blood loss (p < 0.0001) and shorter postoperative length of hospital stay (p < 0.0001) than those who underwent OPN. AB - CONCLUSION: RAPN can offer acceptable surgical outcomes and precision, compared to OPN, with decreased estimated blood loss and hospital stay. ES - 1573-2584 IL - 0301-1623 DI - 10.1007/s11255-016-1323-y DO - https://dx.doi.org/10.1007/s11255-016-1323-y PT - Journal Article ID - 27262849 [pubmed] ID - 10.1007/s11255-016-1323-y [doi] ID - 10.1007/s11255-016-1323-y [pii] PP - ppublish PH - 2016/04/16 [received] PH - 2016/05/14 [accepted] LG - English EP - 20160604 DP - 2016 Oct DC - 20160922 EZ - 2016/06/06 06:00 DA - 2016/06/06 06:00 DT - 2016/06/06 06:00 YR - 2016 RD - 20161219 UP - 20161222 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27262849 <735. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27639794 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Rao N AU - Ramachandran R AU - Tandon N AU - Singh P AU - Kumar R FA - Rao, Niren FA - Ramachandran, Rashmi FA - Tandon, Nikhil FA - Singh, Prabhjot FA - Kumar, Rajeev IN - Rao, Niren. Department of Urology, All India Institute of Medical Sciences, New Delhi, India. IN - Ramachandran, Rashmi. Department of Anesthesiology and Intensive Care, All India Institute of Medical Sciences, New Delhi, India. IN - Tandon, Nikhil. Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India. IN - Singh, Prabhjot. Department of Urology, All India Institute of Medical Sciences, New Delhi, India. IN - Kumar, Rajeev. Department of Urology, All India Institute of Medical Sciences, New Delhi, India. Electronic address: rajeev02@gmail.com. TI - Surgical and Hemodynamic Outcomes in Pheochromocytoma Surgery: A Prospective Cohort Study. SO - Urology. 98:103-106, 2016 Dec AS - Urology. 98:103-106, 2016 Dec NJ - Urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - wsy, 0366151 IO - Urology CP - United States AB - OBJECTIVE: To prospectively evaluate the surgical complications of pheochromocytoma and paraganglioma surgery and assess perioperative hemodynamic outcomes in terms of risk for intraoperative vasodilator use and risk for postoperative vasopressor requirements in these patients. AB - PATIENTS AND METHODS: This was an institutional review board-approved prospective observational study of patients undergoing pheochromocytoma or paraganglioma surgery. Operative and recovery data for all patients undergoing open, laparoscopic, and robotic surgery were analyzed for surgical complications on the modified Clavien-Dindo classification. The need for intraoperative vasodilators for pressure spikes of greater than 180mmHg and vasopressor support after surgery was recorded. Factors predictive of these parameters were assessed. AB - RESULTS: Forty patients underwent 45 procedures including five bilateral adrenalectomies over the 2-year study period. This included 40 adrenalectomies and 5 paraganglioma excisions. Twenty-nine patients had minimally invasive surgery (25 laparoscopic, 4 robot-assisted) and 11 had open surgery. Sixty percent of patients required intraoperative vasodilators for hypertensive crisis, and this was significantly related to the size of the tumor (P=.02). The need for postoperative vasopressors was related to the number of intraoperative pressure spikes (P=.007). Five percent of the patients suffered a complication greater than grade 2 on the Clavien-Dindo classification. AB - CONCLUSION: Pheochromocytoma and paraganglioma surgeries are associated with minimal postoperative morbidity. Larger tumors may be associated with greater intraoperative pressure surges, but this does not impact patient outcomes. AB - Copyright © 2016 Elsevier Inc. All rights reserved. ES - 1527-9995 IL - 0090-4295 DI - S0090-4295(16)30595-7 DO - https://dx.doi.org/10.1016/j.urology.2016.09.004 PT - Journal Article ID - 27639794 [pubmed] ID - S0090-4295(16)30595-7 [pii] ID - 10.1016/j.urology.2016.09.004 [doi] PP - ppublish PH - 2016/06/29 [received] PH - 2016/08/23 [revised] PH - 2016/09/03 [accepted] LG - English EP - 20160914 DP - 2016 Dec DC - 20160918 EZ - 2016/09/19 06:00 DA - 2016/10/22 06:00 DT - 2016/10/22 06:00 YR - 2016 RD - 20161119 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27639794 <736. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27503582 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Canvasser NE AU - Lay AH AU - Koseoglu E AU - Morgan MS AU - Cadeddu JA FA - Canvasser, Noah E FA - Lay, Aaron H FA - Koseoglu, Ersin FA - Morgan, Monica S C FA - Cadeddu, Jeffrey A IN - Canvasser, Noah E. Department of Urology, University of Texas Southwestern Medical Center , Dallas, Texas. IN - Lay, Aaron H. Department of Urology, University of Texas Southwestern Medical Center , Dallas, Texas. IN - Koseoglu, Ersin. Department of Urology, University of Texas Southwestern Medical Center , Dallas, Texas. IN - Morgan, Monica S C. Department of Urology, University of Texas Southwestern Medical Center , Dallas, Texas. IN - Cadeddu, Jeffrey A. Department of Urology, University of Texas Southwestern Medical Center , Dallas, Texas. TI - Posterior Urethral Suspension During Robot-Assisted Radical Prostatectomy Improves Early Urinary Control: A Prospective Cohort Study. SO - Journal of Endourology. 30(10):1089-1094, 2016 Oct AS - J Endourol. 30(10):1089-1094, 2016 Oct NJ - Journal of endourology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - brj, 8807503 IO - J. Endourol. CP - United States KW - incontinence; prostate cancer; prostatectomy AB - PURPOSE: Early urinary control is a major goal for patients undergoing robot-assisted radical prostatectomy (RARP). We report our technique of posterior urethral suspension (PUS) performed at the time of urethrovesical anastomosis. AB - PATIENTS AND METHODS: We prospectively followed men with localized prostate cancer undergoing RARP by a single surgeon from August 2012 to October 2015. Patients before April 2014 underwent only bladder neck preservation (controls), while patients after April 2014 also underwent PUS. Patients were given a modified Expanded Prostate Cancer Index Composite questionnaire, along with questions depicting objective measures of urinary control (type of pad, number of pads, wetness of pad). Time points queried were preoperatively and postoperatively at weeks 1, 2, 4, and 12. Our primary outcome was pad-free survival. AB - RESULTS: Questionnaire response rate was 52% (56/107) for controls and 43% (36/83) for PUS. There were no differences in baseline demographics, preoperative urinary control, intraoperative variables, or postoperative complications between groups. There were few subjective improvements in urinary control for PUS compared with controls. More notable, PUS patients had significantly improved objective measures of urinary control, including less protective incontinence products at 1 and 2 weeks after catheter removal (p<0.03). They also wore fewer pads and had less leakage on each pad that lasted from week 1 to week 4 after catheter removal (p<0.01). PUS patients had pad-free rates of 37%, 47%, 54%, and 60% compared with controls 15%, 18%, 24%, and 36%, at weeks 1, 2, 4, and 12 after catheter removal (p=0.07). AB - CONCLUSION: PUS may improve objective measures of early urinary control compared with controls. With no increase in operative time and no change in complication rates, further work in a randomized setting would provide additional weight to our findings. ES - 1557-900X IL - 0892-7790 DO - https://dx.doi.org/10.1089/end.2016.0220 PT - Journal Article ID - 27503582 [pubmed] ID - 10.1089/end.2016.0220 [doi] PP - ppublish LG - English EP - 20160908 DP - 2016 Oct DC - 20160908 EZ - 2016/08/10 06:00 DA - 2016/08/10 06:00 DT - 2016/08/10 06:00 YR - 2016 RD - 20161018 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27503582 <737. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27479411 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Cadeddu JA FA - Cadeddu, Jeffrey A TI - Re: Robot-Assisted Laparoscopic Donor Nephrectomy vs Standard Laparoscopic Donor Nephrectomy: A Prospective Randomized Comparative Study. SO - Journal of Urology. 196(2):505-6, 2016 Aug AS - J Urol. 196(2):505-6, 2016 Aug NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(16)30109-4 DO - https://dx.doi.org/10.1016/j.juro.2016.03.157 PT - Journal Article ID - 27479411 [pubmed] ID - S0022-5347(16)30109-4 [pii] ID - 10.1016/j.juro.2016.03.157 [doi] PP - ppublish PH - 2016/03/31 [accepted] LG - English EP - 20160405 DP - 2016 Aug DC - 20160802 EZ - 2016/08/02 06:00 DA - 2016/08/02 06:00 DT - 2016/08/02 06:00 YR - 2016 RD - 20160802 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27479411 <738. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27288987 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Maenpaa MM AU - Nieminen K AU - Tomas EI AU - Laurila M AU - Luukkaala TH AU - Maenpaa JU FA - Maenpaa, Minna M FA - Nieminen, Kari FA - Tomas, Eija I FA - Laurila, Marita FA - Luukkaala, Tiina H FA - Maenpaa, Johanna U IN - Maenpaa, Minna M. Department of Gynecology and Obstetrics, Tampere University Hospital, Tampere, Finland. Electronic address: minna.maenpaa@pshp.fi. IN - Nieminen, Kari. Department of Gynecology and Obstetrics, Tampere University Hospital, Tampere, Finland. IN - Tomas, Eija I. Department of Gynecology and Obstetrics, Tampere University Hospital, Tampere, Finland. IN - Laurila, Marita. Department of Pathology, Fimlab Laboratories, Pirkanmaa Hospital District; Tampere, Finland. IN - Luukkaala, Tiina H. School of Health Sciences, University of Tampere, Tampere, Finland; Science Center, Pirkanmaa Hospital District; Tampere, Finland. IN - Maenpaa, Johanna U. Department of Gynecology and Obstetrics, Tampere University Hospital, Tampere, Finland; School of Medicine, University of Tampere, Tampere, Finland. TI - Robotic-assisted vs traditional laparoscopic surgery for endometrial cancer: a randomized controlled trial. SO - American Journal of Obstetrics & Gynecology. 215(5):588.e1-588.e7, 2016 Nov AS - Am J Obstet Gynecol. 215(5):588.e1-588.e7, 2016 Nov NJ - American journal of obstetrics and gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 3ni, 0370476 IO - Am. J. Obstet. Gynecol. CP - United States KW - endometrial cancer; gynecologic surgery; operation time; robotic-assisted surgery; traditional laparoscopic surgery AB - BACKGROUND: Previous studies comparing robotic-assisted laparoscopic surgery to traditional laparoscopic or open surgery in gynecologic oncology have been retrospective. To our knowledge, no prospective randomized trials have thus far been performed on endometrial cancer. AB - OBJECTIVE: We sought to prospectively compare traditional and robotic-assisted laparoscopic surgery for endometrial cancer. AB - STUDY DESIGN: This was a randomized controlled trial. From December 2010 through October 2013, 101 endometrial cancer patients were randomized to hysterectomy, bilateral salpingo-oophorectomy, and pelvic lymphadenectomy either by robotic-assisted laparoscopic surgery or by traditional laparoscopy. The primary outcome measure was overall operation time. The secondary outcome measures included total time spent in the operating room, and surgical outcome (number of lymph nodes harvested, complications, and recovery). The study was powered to show at least a 25% difference in the operation time using 2-sided significance level of .05. The differences between the traditional laparoscopy and the robotic surgery groups were tested by Pearson chi² test, Fisher exact test, or Mann-Whitney test. AB - RESULTS: In all, 99 patients were eligible for analysis. The median operation time in the traditional laparoscopy group (n = 49) was 170 (range 126-259) minutes and in the robotic surgery group (n = 50) was 139 (range 86-197) minutes, respectively (P < .001). The total time spent in the operating room was shorter in the robotic surgery group (228 vs 197 minutes, P < .001). In the traditional laparoscopy group, there were 5 conversions to laparotomy vs none in the robotic surgery group (P = .027). There were no differences as to the number of lymph nodes removed, bleeding, or the length of postoperative hospital stay. Four (8%) vs no (0%) patients (P = .056) had intraoperative complications and 5 (10%) vs 11 (22%) (P = .111) had major postoperative complications in the traditional and robotic surgery groups, respectively. AB - CONCLUSION: In patients with endometrial cancer, robotic-assisted laparoscopic surgery was faster to perform than traditional laparoscopy. Also total time spent in the operation room was shorter in the robotic surgery group and all conversions to laparotomy occurred in the traditional laparoscopy group. Otherwise, the surgical outcome was similar between the groups. Robotic surgery offers an effective and safe alternative in the surgical treatment of endometrial cancer. AB - Copyright © 2016 Elsevier Inc. All rights reserved. ES - 1097-6868 IL - 0002-9378 DI - S0002-9378(16)30314-3 DO - https://dx.doi.org/10.1016/j.ajog.2016.06.005 PT - Journal Article ID - 27288987 [pubmed] ID - S0002-9378(16)30314-3 [pii] ID - 10.1016/j.ajog.2016.06.005 [doi] PP - ppublish PH - 2016/04/12 [received] PH - 2016/05/29 [revised] PH - 2016/06/01 [accepted] LG - English EP - 20160608 DP - 2016 Nov DC - 20160713 EZ - 2016/06/12 06:00 DA - 2016/10/30 06:00 DT - 2016/10/30 06:00 YR - 2016 RD - 20161030 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27288987 <739. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27129542 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Nakauchi M AU - Suda K AU - Susumu S AU - Kadoya S AU - Inaba K AU - Ishida Y AU - Uyama I FA - Nakauchi, Masaya FA - Suda, Koichi FA - Susumu, Shibasaki FA - Kadoya, Shinichi FA - Inaba, Kazuki FA - Ishida, Yoshinori FA - Uyama, Ichiro IN - Nakauchi, Masaya. Division of Upper GI, Department of Surgery, Fujita Health University, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan. IN - Suda, Koichi. Division of Upper GI, Department of Surgery, Fujita Health University, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan. ko-suda@nifty.com. IN - Susumu, Shibasaki. Division of Upper GI, Department of Surgery, Fujita Health University, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan. IN - Kadoya, Shinichi. Division of Upper GI, Department of Surgery, Fujita Health University, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan. IN - Inaba, Kazuki. Division of Upper GI, Department of Surgery, Fujita Health University, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan. IN - Ishida, Yoshinori. Division of Upper GI, Department of Surgery, Fujita Health University, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan. IN - Uyama, Ichiro. Division of Upper GI, Department of Surgery, Fujita Health University, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan. TI - Comparison of the long-term outcomes of robotic radical gastrectomy for gastric cancer and conventional laparoscopic approach: a single institutional retrospective cohort study. SO - Surgical Endoscopy. 30(12):5444-5452, 2016 Dec AS - Surg Endosc. 30(12):5444-5452, 2016 Dec NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc CP - Germany KW - Gastric cancer; Long-term outcomes; Pancreatic fistula; Retrospective cohort study; Robotic gastrectomy AB - BACKGROUND: Robotic gastrectomy (RG) for gastric cancer (GC) has been increasingly performed over the last decade. The technical feasibility and safety of RG for GC, predominantly early GC, have previously been reported; however, few studies have evaluated the oncological outcomes. This study aimed to determine the long-term outcomes of RG for GC compared with those of conventional laparoscopic gastrectomy (LG). AB - METHODS: Of the 521 consecutive patients with GC who underwent radical gastrectomy at our institution between 2009 and 2012, 84 consecutive patients who underwent RG and 437 patients who received LG were enrolled in this study. Long-term outcomes including the 3-year overall survival (3yOS) and 3-year recurrence-free survival rates (3yRFS) were examined retrospectively. AB - RESULTS: In the RG group, the 3yOS rates stratified by pathological stage according to the Japanese classification of gastric carcinoma (IA, IB, II, and III) were 94.7, 90.9, 89.5, and 62.5 %, respectively. No differences in 3yOS (RG, 86.9 % vs. LG, 88.8 %; p = 0.636) or 3yRFS (RG, 86.9 % vs. LG, 86.3 %; p = 0.905) were observed between the groups. 3yOS was strongly associated with cancer recurrence within 3 years (p < 0.001), while 3yRFS was associated with tumor size > 30 mm (p < 0.001), clinical stage > IB (p < 0.001), estimated blood loss > 50 mL (p = 0.033), and postoperative pancreatic fistula CD grade > III) (p = 0.035). AB - CONCLUSIONS: RG for GC was feasible and safe from the oncological point of view in a cohort including a considerable number of patients with advanced GC. ES - 1432-2218 IL - 0930-2794 DI - 10.1007/s00464-016-4904-z DO - https://dx.doi.org/10.1007/s00464-016-4904-z PT - Journal Article ID - 27129542 [pubmed] ID - 10.1007/s00464-016-4904-z [doi] ID - 10.1007/s00464-016-4904-z [pii] PP - ppublish PH - 2016/01/12 [received] PH - 2016/04/02 [accepted] LG - English EP - 20160429 DP - 2016 Dec DC - 20160430 EZ - 2016/05/01 06:00 DA - 2016/05/01 06:00 DT - 2016/05/01 06:00 YR - 2016 RD - 20161117 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27129542 <740. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27059971 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Shakir F AU - Jan H AU - Kent A FA - Shakir, Fevzi FA - Jan, Haider FA - Kent, Andrew IN - Shakir, Fevzi. Minimal Access Therapy Training Unit (MATTU), Royal Surrey County Hospital, Egerton Road, Guildford, Surrey, GU2 7XX, UK. fevzi@doctors.org.uk. IN - Jan, Haider. Epsom and St Helier University Hospitals NHS Trust, Epsom Hospital, Dorking Road, Epsom, Surrey, KT18 7EG, UK. IN - Kent, Andrew. Minimal Access Therapy Training Unit (MATTU), Royal Surrey County Hospital, Egerton Road, Guildford, Surrey, GU2 7XX, UK. TI - 3D straight-stick laparoscopy versus 3D robotics for task performance in novice surgeons: a randomised crossover trial. SO - Surgical Endoscopy. 30(12):5380-5387, 2016 Dec AS - Surg Endosc. 30(12):5380-5387, 2016 Dec NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc CP - Germany KW - 3D; Errors; Laparoscopy; Novices; Performance; Robotics AB - BACKGROUND: The advent of three-dimensional passive stereoscopic imaging has led to the development of 3D laparoscopy. In simulation tasks, a reduction in error rate and performance time is seen with 3D compared to two-dimensional (2D) laparoscopy with both novice and expert surgeons. Robotics utilises 3D and instrument articulation through a console interface. Robotic trials have demonstrated that tasks performed in 3D produced fewer errors and quicker performance times compared with those in 2D. It was therefore perceived that the main advantage of robotic surgery was in fact 3D. Our aim was to compare 3D straight-stick laparoscopic task performance (3D) with robotic 3D (Robot), to determine whether robotic surgery confers additional benefit over and above 3D visualisation. AB - METHODS: We randomised 20 novice surgeons to perform four validated surgical tasks, either with straight-stick 3D laparoscopy followed by 3D robotic surgery or in the reverse order. The trial was conducted in two fully functional operating theatres. The primary outcome of the study was the error rate as defined for each task, and the secondary outcome was the time taken to complete each task. The participants were asked to perform the tasks as quickly and as accurately as possible. Data were analysed using SPSS version 21. AB - RESULTS: The median error rate for completion of all four tasks with the robot was 2.75 and 5.25 for 3D with a P value <0.001. The median performance time for completion of all four tasks with the robot was 157.1 and 342.5 s for 3D with a P value <0.001. AB - CONCLUSIONS: Our study has shown that for novice surgeons, there is a significant benefit in a simulated setting of 3D robotic systems over 3D straight-stick laparoscopy, in terms of reduced error rate and quicker task performance time. ES - 1432-2218 IL - 0930-2794 DI - 10.1007/s00464-016-4893-y DO - https://dx.doi.org/10.1007/s00464-016-4893-y PT - Journal Article ID - 27059971 [pubmed] ID - 10.1007/s00464-016-4893-y [doi] ID - 10.1007/s00464-016-4893-y [pii] PP - ppublish PH - 2015/07/05 [received] PH - 2016/02/28 [accepted] LG - English EP - 20160408 DP - 2016 Dec DC - 20160409 EZ - 2016/04/10 06:00 DA - 2016/04/10 06:00 DT - 2016/04/10 06:00 YR - 2016 RD - 20161117 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=27059971 <741. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26991489 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Chang H AU - Noh J AU - Lee J AU - Kim S AU - Koo KT AU - Kim TI AU - Seol YJ AU - Lee YM AU - Ku Y AU - Rhyu IC FA - Chang, Hyeyoon FA - Noh, Jiyoung FA - Lee, Jungwon FA - Kim, Sungtae FA - Koo, Ki-Tae FA - Kim, Tae-Il FA - Seol, Yang-Jo FA - Lee, Yong-Moo FA - Ku, Young FA - Rhyu, In-Chul IN - Chang, Hyeyoon. Department of Periodontology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea. IN - Noh, Jiyoung. Department of Periodontology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea. IN - Lee, Jungwon. Department of Periodontology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea. IN - Kim, Sungtae. Department of Periodontology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea. IN - Koo, Ki-Tae. Department of Periodontology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea. IN - Kim, Tae-Il. Department of Periodontology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea. IN - Seol, Yang-Jo. Department of Periodontology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea. IN - Lee, Yong-Moo. Department of Periodontology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea. IN - Ku, Young. Department of Periodontology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea. IN - Rhyu, In-Chul. Department of Periodontology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea. TI - Relief of Injection Pain During Delivery of Local Anesthesia by Computer-Controlled Anesthetic Delivery System for Periodontal Surgery: Randomized Clinical Controlled Trial. SO - Journal of Periodontology. 87(7):783-9, 2016 Jul AS - J Periodontol. 87(7):783-9, 2016 Jul NJ - Journal of periodontology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - jmt, 8000345 IO - J. Periodontol. SB - Dental Journals SB - Index Medicus CP - United States KW - Anesthesia, local; pain; pain measurement; periodontal debridement; periodontitis AB - BACKGROUND: Pain from local anesthetic injection makes patients anxious when visiting a dental clinic. This study aims to determine differences in pain according to types of local anesthetizing methods and to identify the possible contributing factors (e.g., dental anxiety, stress, and sex). AB - METHODS: Thirty-one patients who underwent open-flap debridement in maxillary premolar and molar areas during treatment for chronic periodontitis were evaluated for this study. A randomized, split-mouth, single-masked clinical trial was implemented. The dental anxiety scale (DAS) and perceived stress scale (PSS) were administered before surgery. Two lidocaine ampules for each patient were used for local infiltration anesthesia (supraperiosteal injection). Injection pain was measured immediately after local infiltration anesthesia using the visual analog pain scale (VAS) questionnaire. Results from the questionnaire were used to assess degree of pain patients feel when a conventional local anesthetic technique (CNV) is used compared with a computer-controlled anesthetic delivery system (CNR). AB - RESULTS: DAS and PSS did not correlate to injection pain. VAS scores were lower for CNR than for CNV regardless of the order in which anesthetic procedures were applied. VAS score did not differ significantly with sex. Pearson coefficient for correlation between VAS scores for the two procedures was 0.80, also indicating a strong correlation. AB - CONCLUSION: Within the limitations of the present study, relief from injection pain is observed using CNR. ES - 1943-3670 IL - 0022-3492 DO - https://dx.doi.org/10.1902/jop.2016.150448 PT - Journal Article ID - 26991489 [pubmed] ID - 10.1902/jop.2016.150448 [doi] PP - ppublish LG - English EP - 20160318 DP - 2016 Jul DC - 20160701 EZ - 2016/03/19 06:00 DA - 2016/03/19 06:00 DT - 2016/03/19 06:00 YR - 2016 RD - 20160701 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=26991489 <742. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 26784645 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Bahler CD AU - Sundaram CP AU - Kella N AU - Lucas SM AU - Boger MA AU - Gardner TA AU - Koch MO FA - Bahler, Clinton D FA - Sundaram, Chandru P FA - Kella, Naveen FA - Lucas, Steven M FA - Boger, Michelle A FA - Gardner, Thomas A FA - Koch, Michael O IN - Bahler, Clinton D. Department of Urology, Indiana University, Indianapolis, Indiana. IN - Sundaram, Chandru P. Department of Urology, Indiana University, Indianapolis, Indiana. IN - Kella, Naveen. The Urology Place, San Antonio, Texas. IN - Lucas, Steven M. Department of Urology, Indiana University, Indianapolis, Indiana. IN - Boger, Michelle A. Department of Urology, Indiana University, Indianapolis, Indiana. IN - Gardner, Thomas A. Department of Urology, Indiana University, Indianapolis, Indiana. IN - Koch, Michael O. Department of Urology, Indiana University, Indianapolis, Indiana. Electronic address: miokoch@iupui.edu. TI - A Parallel Randomized Clinical Trial Examining the Return of Urinary Continence after Robot-Assisted Radical Prostatectomy with or without a Small Intestinal Submucosa Bladder Neck Sling. SO - Journal of Urology. 196(1):179-84, 2016 Jul AS - J Urol. 196(1):179-84, 2016 Jul NJ - The Journal of urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - kc7, 0376374 IO - J. Urol. SB - Core Clinical Journals (AIM) SB - Index Medicus CP - United States KW - laparoscopy; prostatic neoplasms; robotics; urinary incontinence AB - PURPOSE: Urinary continence is a driver of quality of life after radical prostatectomy. In this study we evaluated the impact of a biological bladder neck sling on the return of urinary continence after robot-assisted radical prostatectomy. AB - MATERIALS AND METHODS: This study compared early continence in patients undergoing robot-assisted radical prostatectomy with a sling and without a sling in a 2-group, 1:1, parallel, randomized controlled trial. Patients were blinded to group assignment. The primary outcome was defined as urinary continence (0 to 1 pad per day) at 1 month postoperatively. Inclusion criteria were organ confined prostate cancer and a prostate specific antigen less than 15 ng/ml. Exclusion criteria were any prior surgery on the prostate, a history of neurogenic bladder and history of pelvic radiation. A chi-squared test was used for the primary outcome. AB - RESULTS: A total of 147 patients were randomized (control 74, sling 73) and 92% were available for primary end point analysis at 1 month. There were no significant differences in baseline or perioperative data except that operating room time was 20.1 minutes longer for the sling group (p=0.04). The continence rate was similar between the control and sling groups at 1 month (47.1% vs 55.2%, p=0.34) and 12 months (86.7% vs 94.5%, p=0.15), respectively. Adverse events were similar between the control and sling groups (10.8% vs 13.7%, p=0.59). AB - CONCLUSIONS: The application of an absorbable urethral sling at robot-assisted radical prostatectomy was well tolerated with no increase in obstructive symptoms in this randomized trial. However, the sling failed to show a significant improvement in continence. AB - Copyright © 2016 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. ES - 1527-3792 IL - 0022-5347 DI - S0022-5347(16)00039-2 DO - https://dx.doi.org/10.1016/j.juro.2016.01.010 PT - Journal Article ID - 26784645 [pubmed] ID - S0022-5347(16)00039-2 [pii] ID - 10.1016/j.juro.2016.01.010 [doi] PP - ppublish PH - 2016/01/08 [accepted] LG - English EP - 20160116 DP - 2016 Jul DC - 20160620 EZ - 2016/01/20 06:00 DA - 2016/01/20 06:00 DT - 2016/01/20 06:00 YR - 2016 RD - 20160620 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=26784645 <743. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 25782919 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - In-Data-Review AU - Bae DS AU - Kim SJ AU - Koo do H AU - Paek SH AU - Kwon H AU - Chai YJ AU - Choi JY AU - Lee KE AU - Youn YK FA - Bae, Dong Sik FA - Kim, Su-Jin FA - Koo, Do Hoon FA - Paek, Se-Hyun FA - Kwon, Hyungju FA - Chai, Young Jun FA - Choi, June Young FA - Lee, Kyu Eun FA - Youn, Yeo-Kyu IN - Bae, Dong Sik. Department of Surgery, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea. IN - Kim, Su-Jin. Department of Surgery, Seoul National University College of Medicine and Hospital, Cancer Research Institute, Division of Surgery, Thyroid Center, Seoul National University Cancer Hospital, Seoul, Korea. IN - Koo, Do Hoon. Department of Surgery, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea. IN - Paek, Se-Hyun. Department of Surgery, Seoul National University College of Medicine and Hospital, Cancer Research Institute, Division of Surgery, Thyroid Center, Seoul National University Cancer Hospital, Seoul, Korea. IN - Kwon, Hyungju. Department of Surgery, Seoul National University College of Medicine and Hospital, Cancer Research Institute, Division of Surgery, Thyroid Center, Seoul National University Cancer Hospital, Seoul, Korea. IN - Chai, Young Jun. Department of Surgery, Seoul National University Boramae Medical Center and College of Medicine, Seoul, Korea. IN - Choi, June Young. Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Korea. IN - Lee, Kyu Eun. Department of Surgery, Seoul National University College of Medicine and Hospital, Cancer Research Institute, Division of Surgery, Thyroid Center, Seoul National University Cancer Hospital, Seoul, Korea. IN - Youn, Yeo-Kyu. Department of Surgery, Seoul National University College of Medicine and Hospital, Cancer Research Institute, Division of Surgery, Thyroid Center, Seoul National University Cancer Hospital, Seoul, Korea. TI - Prospective, randomized controlled trial on use of ropivacaine after robotic thyroid surgery: Effects on postoperative pain. SO - Head & Neck. 38 Suppl 1:E588-93, 2016 Apr AS - Head Neck. 38 Suppl 1:E588-93, 2016 Apr NJ - Head & neck PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - g1p, 8902541 IO - Head Neck SB - Index Medicus CP - United States KW - acute pain; bilateral axillo-breast approach (BABA); postoperative pain; robotic thyroid surgery; ropivacaine AB - BACKGROUND: We evaluated the effects of ropivacaine for pain relief after robotic thyroid surgery. AB - METHODS: One hundred eight patients scheduled for robotic thyroid surgery were randomized into ropivacaine (n=54) or control (n=54) groups. After surgery, 40 mL of 0.25% ropivacaine or 0.9% saline (control) was instilled into the skin flap. Postoperative pain intensity (visual analog scale [VAS]), analgesic requirements (fentanyl), and adverse events were assessed at 1, 2, 4, 8, 16, and 24 hours postoperatively. AB - RESULTS: One hundred three patients completed the study protocol. VAS scores were lower in the ropivacaine group than the control group (p=.010); however, VAS scores were not significantly different after 8 hours postoperatively. Total analgesic consumption was higher in controls than ropivacaine-treated patients (p=.01). Adverse events did not differ between the 2 groups. AB - CONCLUSION: Ropivacaine instillation after robotic thyroid surgery reduces acute postoperative pain and analgesic requirements without adverse events. © 2015 Wiley Periodicals, Inc. Head Neck 38: E-E, 2016. AB - Copyright © 2015 Wiley Periodicals, Inc. ES - 1097-0347 IL - 1043-3074 DO - https://dx.doi.org/10.1002/hed.24045 PT - Journal Article ID - 25782919 [pubmed] ID - 10.1002/hed.24045 [doi] PP - ppublish PH - 2015/03/06 [accepted] LG - English EP - 20150706 DP - 2016 Apr DC - 20160426 EZ - 2015/03/19 06:00 DA - 2015/03/19 06:00 DT - 2015/03/19 06:00 YR - 2016 RD - 20160426 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=25782919 <744. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28483330 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Dalela D AU - Jeong W AU - Prasad MA AU - Sood A AU - Abdollah F AU - Diaz M AU - Karabon P AU - Sammon J AU - Jamil M AU - Baize B AU - Simone A AU - Menon M FA - Dalela, Deepansh FA - Jeong, Wooju FA - Prasad, Madhu-Ashni FA - Sood, Akshay FA - Abdollah, Firas FA - Diaz, Mireya FA - Karabon, Patrick FA - Sammon, Jesse FA - Jamil, Marcus FA - Baize, Brad FA - Simone, Andrea FA - Menon, Mani IN - Dalela, Deepansh. VUI Center for Outcomes Research, Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI, USA. Electronic address: ddalela1@hfhs.org. IN - Jeong, Wooju. VUI Center for Outcomes Research, Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI, USA. IN - Prasad, Madhu-Ashni. VUI Center for Outcomes Research, Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI, USA. IN - Sood, Akshay. VUI Center for Outcomes Research, Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI, USA. IN - Abdollah, Firas. VUI Center for Outcomes Research, Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI, USA. IN - Diaz, Mireya. VUI Center for Outcomes Research, Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI, USA. IN - Karabon, Patrick. VUI Center for Outcomes Research, Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI, USA. IN - Sammon, Jesse. VUI Center for Outcomes Research, Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI, USA; Department of Urology, Maine Medical Center, Portland, ME, USA. IN - Jamil, Marcus. VUI Center for Outcomes Research, Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI, USA. IN - Baize, Brad. VUI Center for Outcomes Research, Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI, USA. IN - Simone, Andrea. VUI Center for Outcomes Research, Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI, USA. IN - Menon, Mani. VUI Center for Outcomes Research, Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI, USA. TI - A Pragmatic Randomized Controlled Trial Examining the Impact of the Retzius-sparing Approach on Early Urinary Continence Recovery After Robot-assisted Radical Prostatectomy. SO - European Urology. , 2017 May 05 AS - Eur Urol. , 2017 May 05 NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. CP - Switzerland KW - Prostate cancer; Randomized controlled trial; Retzius sparing; Robot-assisted radical prostatectomy; Urinary bother; Urinary continence AB - BACKGROUND: Retzius-sparing (posterior) robot-assisted radical prostatectomy (RARP) may expedite postoperative urinary continence recovery. AB - OBJECTIVE: To compare the short-term (<3 mo) urinary continence (UC), urinary function (UF), and UF-related bother outcomes of posterior RARP compared with standard anterior approach RARP. AB - DESIGN, SETTING, AND PARTICIPANTS: A total of 120 patients aged 40-75 yr with low-intermediate-risk prostate cancer (per the National Comprehensive Cancer Network guidelines) underwent primary RARP at a tertiary care institution. AB - INTERVENTION: Eligible men were randomized to receive either posterior (n=60) or anterior (n=60) RARP. AB - OUTCOME MEASUREMENTS AND STATISTICAL ANALYSES: Primary outcome was UC (defined as 0 pads/one security liner per day) 1 week after catheter removal. Secondary outcomes were short-term (<3 mo) UC recovery, and UF and UF-related bother scores (measured by the International Prostate Symptom Score [IPSS] and IPSS quality-of-life scores, respectively) assessed at 1 and 2 wk, and 1 and 3 mo following catheter removal. Continence outcomes were objectively verified using 24-hr pad weights. UC recovery was analyzed using Kaplan-Meier method and Cox proportional hazards regression; UF and UF-related bother outcomes were compared using linear generalized estimating equations (GEEs). Perioperative complications, positive surgical margin, and biochemical recurrence-free survival (BCRFS) represent secondary outcomes reported in the study. AB - RESULTS AND LIMITATIONS: Compared with 48% in the anterior arm, 71% men undergoing posterior RARP were continent 1 wk after catheter removal (p=0.01); corresponding median 24-h pad weights were 25 and 5g (p=0.001). Median time to continence in posterior versus anterior RARP was 2 and 8 d postcatheter removal, respectively (log-rank p=0.02); results were confirmed on multivariable regression analyses. GEE analyses showed that UF-related bother (but not UF) scores were significantly lower in the posterior versus anterior RARP group at 1 wk, 2 wk, and 1 mo on GEE analyses. Incidence of postoperative complications (12% anterior vs 18% posterior) and probability of BCRFS (0.91 vs 0.91) were comparable in the two arms. AB - CONCLUSIONS: In this single-center randomized study, the Retzius-sparing approach of RARP resulted in earlier recovery of UC and lower UF-related bother compared with standard RARP. These results require long-term validation and reproduction by other centers, as well as studies on men with high-risk localized disease. AB - PATIENT SUMMARY: In our hands, men with low-intermediate-risk prostate cancer undergoing Retzius-sparing robot-assisted radical prostatectomy (RARP) had earlier recovery of urinary continence and lower urinary function-related bother than those undergoing standard RARP. AB - Copyright © 2017 European Association of Urology. Published by Elsevier B.V. All rights reserved. ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(17)30339-1 DO - https://dx.doi.org/10.1016/j.eururo.2017.04.029 PT - Journal Article ID - S0302-2838(17)30339-1 [pii] ID - 10.1016/j.eururo.2017.04.029 [doi] PP - aheadofprint PH - 2016/11/13 [received] PH - 2017/04/21 [accepted] LG - English EP - 20170505 DP - 2017 May 05 DC - 20170509 EZ - 2017/05/10 06:00 DA - 2017/05/10 06:00 DT - 2017/05/10 06:00 YR - 2017 RD - 20170509 UP - 20170511 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=28483330 <745. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28479201 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Dal Moro F FA - Dal Moro, Fabrizio IN - Dal Moro, Fabrizio. Department of Surgery, Oncology and Gastroenterology-Urology, University of Padova, Padova, Italy. Electronic address: fabrizio.dalmoro@unipd.it. TI - Re: Vladimir Student Jr., Ales Vidlar, Michal Grepl, Igor Hartmann, Eva Buresova, Vladimir Student. Advanced Reconstruction of Vesicourethral Support (ARVUS) during Robot-assisted Radical Prostatectomy: One-year Functional Outcomes in a Two-group Randomised Controlled Trial. Eur Urol 2017;71:822-30: CoRPUS and ARVUS. SO - European Urology. , 2017 May 04 AS - Eur Urol. , 2017 May 04 NJ - European urology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - enm, 7512719 IO - Eur. Urol. CP - Switzerland ES - 1873-7560 IL - 0302-2838 DI - S0302-2838(17)30330-5 DO - https://dx.doi.org/10.1016/j.eururo.2017.04.022 PT - Letter ID - S0302-2838(17)30330-5 [pii] ID - 10.1016/j.eururo.2017.04.022 [doi] PP - aheadofprint PH - 2017/03/21 [received] PH - 2017/04/18 [accepted] LG - English EP - 20170504 DP - 2017 May 04 DC - 20170508 EZ - 2017/05/09 06:00 DA - 2017/05/10 06:00 DT - 2017/05/10 06:00 YR - 2017 RD - 20170508 UP - 20170511 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=28479201 <746. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28477228 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Bae J AU - Kim HC AU - Hong DM FA - Bae, Junyeol FA - Kim, Hyun-Chang FA - Hong, Deok Man IN - Bae, Junyeol. Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Korea. IN - Kim, Hyun-Chang. Department of Anesthesiology and Pain Medicine, Keimyung University Dongsan Medical Center, Daegu, Korea. IN - Hong, Deok Man. Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Korea. mellyn7@gmail.com. TI - Intrathecal morphine for postoperative pain control following robot-assisted prostatectomy: a prospective randomized trial. SO - Journal of Anesthesia. , 2017 May 05 AS - J. ANESTH.. , 2017 May 05 NJ - Journal of anesthesia PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 8905667 IO - J Anesth CP - Japan KW - Injections; Morphine; Pain; Postoperative; Prostatectomy; Spinal AB - PURPOSE: Robot-assisted laparoscopic prostatectomy (RALP) is minimally invasive surgery, but also causes moderate to severe pain during the immediate postoperative period. We evaluated the efficacy and safety of intrathecal morphine (ITM) for postoperative pain control in patients undergoing RALP. AB - METHODS: Thirty patients scheduled for RALP were randomly assigned into one of two groups. In the ITM group (n = 15), postoperative pain was managed using 300 micro g intrathecal morphine with intravenous patient-controlled analgesia (IV-PCA). In the IV-PCA group (n = 15), only intravenous patient-controlled analgesia was used. The numerical pain score (NPS; 0 = no pain, 100 = worst pain imaginable), postoperative IV-PCA requirements and opioid-related complications including nausea, vomiting, dizziness, headache and pruritus were compared between the two groups. AB - RESULTS: The NPSs on coughing were 20 (IQR 10-50) in the ITM group and 60 (IQR 40-80) in the IV-PCA group at postoperative 24 h (p = 0.001). The NPSs were significantly lower in the ITM group up to postoperative 24 h. The ITM group showed less morphine consumption at postoperative 24 h in the ITM group than in the IV-PCA group [5 (IQR 3-15) mg vs 17 (IQR 11-24) mg, p = 0.001]. Complications associated with morphine were comparable between the two groups and respiratory depression was not reported in either group. AB - CONCLUSION: Intrathecal morphine provided more satisfactory analgesia without serious complications during the early postoperative period in patients undergoing RALP. ES - 1438-8359 IL - 0913-8668 DI - 10.1007/s00540-017-2356-9 DO - https://dx.doi.org/10.1007/s00540-017-2356-9 PT - Journal Article ID - 10.1007/s00540-017-2356-9 [doi] ID - 10.1007/s00540-017-2356-9 [pii] PP - aheadofprint PH - 2016/12/14 [received] PH - 2017/04/06 [accepted] LG - English EP - 20170505 DP - 2017 May 05 DC - 20170506 EZ - 2017/05/07 06:00 DA - 2017/05/10 06:00 DT - 2017/05/10 06:00 YR - 2017 RD - 20170506 UP - 20170511 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=28477228 <747. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28463759 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Salehi S AU - Avall-Lundqvist E AU - Legerstam B AU - Carlson JW AU - Falconer H FA - Salehi, Sahar FA - Avall-Lundqvist, Elisabeth FA - Legerstam, Berit FA - Carlson, Joseph W FA - Falconer, Henrik IN - Salehi, Sahar. Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden; Division of Obstetrics and Gynecology, Karolinska University Hospital, Stockholm, Sweden. Electronic address: sahar.salehi@sll.se. IN - Avall-Lundqvist, Elisabeth. Department of Oncology, Linkoping University, Linkoping, Sweden; Department of Clinical Experimental Medicine, Linkoping University, Linkoping, Sweden; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden. IN - Legerstam, Berit. Division of Obstetrics and Gynecology, Karolinska University Hospital, Stockholm, Sweden. IN - Carlson, Joseph W. Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden; Department of Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden. IN - Falconer, Henrik. Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden; Division of Obstetrics and Gynecology, Karolinska University Hospital, Stockholm, Sweden. TI - Robot-assisted laparoscopy versus laparotomy for infrarenal paraaortic lymphadenectomy in women with high-risk endometrial cancer: A randomised controlled trial. SO - European Journal of Cancer. 79:81-89, 2017 Apr 29 AS - Eur J Cancer. 79:81-89, 2017 Apr 29 NJ - European journal of cancer (Oxford, England : 1990) PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - arv, 9005373 IO - Eur. J. Cancer CP - England KW - Endometrial cancer; Laparotomy; Lymph node count; Paraaortic lymphadenectomy; Robotic surgery AB - PURPOSE: To investigate if robot-assisted laparoscopic surgery (RALS) was non-inferior to laparotomy (LT) in harvesting infrarenal paraaortic lymph nodes in patients with presumed stage I-II high-risk endometrial cancer. AB - PATIENTS AND METHODS: Patients with histologically proven endometrial cancer, presumed stage I-II with high-risk tumour features, were randomised to hysterectomy, bilateral salpingo-oophorectomy, pelvic and paraaortic lymphadenectomy by either RALS or LT. Primary outcome was paraaortic lymph node count. Secondary outcomes were perioperative events, postoperative complications and total health care cost. AB - RESULTS: Overall 120 patients were randomised and 96 patients were included in the per protocol analysis. Demographic, clinical and tumour characteristics were evenly distributed between groups. Mean (+/-SD) paraaortic lymph node count was 20.9 (+/-9.6) for RALS and 22 (+/-11, p = 0.45) for LT. The difference of means was within the non-inferiority margin (-1.6, 95% CI -5.78, 2.57). Mean pelvic node count was lower after RALS (28 +/- 10 versus 22 +/- 8, p < 0.001). There was no difference in perioperative complications or readmissions between the groups. Operation time was longer (p < 0.001) but total blood loss less (<0.001) and hospital stay shorter (<0.001) in RALS group than LT group. Health care costs for RALS was significantly lower (mean difference $1568 USD/1225 Euro, p < 0.05). AB - CONCLUSION: Our results demonstrate non-inferiority in paraaortic lymph node count, comparable complication rates, shorter hospital length and lower total cost for RALS over laparotomy. Generalisability of the latter finding requires a high-volume setting and high surgical proficiency. In women with high-risk endometrial cancer confined to the uterus, RALS is a valid treatment modality. AB - CLINICAL TRIALS REGISTRATIONS: ClinicalTrials.govNCT01847703. AB - Copyright © 2017 Elsevier Ltd. All rights reserved. ES - 1879-0852 IL - 0959-8049 DI - S0959-8049(17)30877-8 DO - https://dx.doi.org/10.1016/j.ejca.2017.03.038 PT - Journal Article ID - S0959-8049(17)30877-8 [pii] ID - 10.1016/j.ejca.2017.03.038 [doi] PP - aheadofprint PH - 2017/02/02 [received] PH - 2017/03/16 [revised] PH - 2017/03/26 [accepted] LG - English EP - 20170429 DP - 2017 Apr 29 DC - 20170502 EZ - 2017/05/03 06:00 DA - 2017/05/04 06:00 DT - 2017/05/04 06:00 YR - 2017 RD - 20170502 UP - 20170505 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=28463759 <748. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28143703 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Madhuri TK AU - Butler-Manuel S FA - Madhuri, Thumuluru Kavitha FA - Butler-Manuel, Simon IN - Madhuri, Thumuluru Kavitha. Department of Gynaecological Oncology, Royal Surrey County Hospital NHS Foundation Trust, UK Epicenter for Gynae Robotic Surgery, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom. IN - Butler-Manuel, Simon. Department of Gynaecological Oncology, Royal Surrey County Hospital NHS Foundation Trust, UK Epicenter for Gynae Robotic Surgery, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom. TI - Robotic-assisted vs traditional laparoscopic surgery for endometrial cancer: a randomized controlled trial. SO - American Journal of Obstetrics & Gynecology. , 2017 Jan 29 AS - Am J Obstet Gynecol. , 2017 Jan 29 NJ - American journal of obstetrics and gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 3ni, 0370476 IO - Am. J. Obstet. Gynecol. CP - United States ES - 1097-6868 IL - 0002-9378 DI - S0002-9378(17)30153-9 DO - https://dx.doi.org/10.1016/j.ajog.2017.01.031 PT - Letter ID - S0002-9378(17)30153-9 [pii] ID - 10.1016/j.ajog.2017.01.031 [doi] PP - aheadofprint PH - 2016/11/20 [received] PH - 2017/01/19 [accepted] LG - English EP - 20170129 DP - 2017 Jan 29 DC - 20170201 EZ - 2017/02/02 06:00 DA - 2017/02/02 06:00 DT - 2017/02/02 06:00 YR - 2017 RD - 20170323 UP - 20170324 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=28143703 <749. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28009229 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Chauvet D AU - Hans S AU - Missistrano A AU - Rebours C AU - Bakkouri WE AU - Lot G FA - Chauvet, Dorian FA - Hans, Stephane FA - Missistrano, Antoine FA - Rebours, Celeste FA - Bakkouri, Wissame El FA - Lot, Guillaume IN - Chauvet, Dorian. Department of Neurosurgery and. IN - Hans, Stephane. Department of Head and Neck Surgery, Hopital Europeen Georges Pompidou, Paris, France; and. IN - Missistrano, Antoine. Intuitive Surgical, Sunnyvale, California. IN - Rebours, Celeste. ENT Department, Fondation Ophtalmologique Rothschild. IN - Bakkouri, Wissame El. ENT Department, Fondation Ophtalmologique Rothschild. IN - Lot, Guillaume. Department of Neurosurgery and. TI - Transoral robotic surgery for sellar tumors: first clinical study. SO - Journal of Neurosurgery. :1-8, 2016 Dec 23 AS - J Neurosurg. :1-8, 2016 Dec 23 NJ - Journal of neurosurgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - jd3, 0253357 IO - J. Neurosurg. CP - United States KW - TORS = transoral robotic surgery; da Vinci system; pituitary adenoma; robotic assisted surgery; skull base surgery; surgical technique; transoral robotic surgery; transsphenoidal surgery AB - OBJECTIVE The aim of this study was to confirm the feasibility of an innovative transoral robotic surgery (TORS), using the da Vinci Surgical System, for patients with sellar tumors. This technique was designed to offer a new minimally invasive approach, without soft-palate splitting, that avoids the rhinological side effects of classic endonasal approaches. METHODS The authors performed a prospective study of TORS in patients with symptomatic sellar tumors. Specific anatomical features were required for inclusion in the study and were determined on the basis of preoperative open-mouth CT scans of the brain. The main outcome measure was sellar accessibility using the robot. Resection quality, mean operative time, postoperative changes in patients' vision, side effects, and complications were additionally reported. RESULTS Between February and May 2016, 4 patients (all female, mean age 49.5 years) underwent TORS for resection of sellar tumors as participants in this study. All patients presented with symptomatic visual deficits confirmed as bitemporal hemianopsia. All tumors had a suprasellar portion and a cystic part. In all 4 cases, the operation was performed via TORS, without the need for a second surgery. Sella turcica accessibility was satisfactory in all cases. In 3 cases, tumor resection was complete. The mean operative time was 2 hours 43 minutes. Three patients had a significant visual improvement at Day 1. No rhinological side effects or complications in patients occurred. No pathological examination was performed regarding the fluid component of the tumors. There was 1 postoperative delayed CSF leak and 1 case of transient diabetes insipidus. Side effects specific to TORS included minor sore throat, transient hypernasal speech, and 1 case of delayed otitis media. The mean length of hospital stay and mean follow up were 8.25 days and 82 days, respectively. CONCLUSIONS To our knowledge, this is the first report of the surgical treatment of sellar tumors by means of a minimally invasive TORS. This approach using the da Vinci Surgical System seems feasible and constitutes an innovative neurosurgical technique that may avoid the adverse side effects and technical disadvantages of the classic transsphenoidal route. Moreover, TORS allows an inferosuperior approach to the sella turcica, which is a key point, as the tumor is approached in the direction of its growth. ES - 1933-0693 IL - 0022-3085 DO - https://dx.doi.org/10.3171/2016.9.JNS161638 PT - Journal Article ID - 10.3171/2016.9.JNS161638 [doi] PP - aheadofprint LG - English EP - 20161223 DP - 2016 Dec 23 DC - 20161223 EZ - 2016/12/24 06:00 DA - 2016/12/24 06:00 DT - 2016/12/24 06:00 YR - 2016 RD - 20170316 UP - 20170317 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=28009229 <750. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28265777 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Holloway RW AU - Ahmad S AU - Kendrick JE AU - Bigsby GE AU - Brudie LA AU - Ghurani GB AU - Stavitzski NM AU - Gise JL AU - Ingersoll SB AU - Pepe JW FA - Holloway, Robert W FA - Ahmad, Sarfraz FA - Kendrick, James E FA - Bigsby, Glenn E FA - Brudie, Lorna A FA - Ghurani, Giselle B FA - Stavitzski, Nicole M FA - Gise, Jasmine L FA - Ingersoll, Susan B FA - Pepe, Julie W IN - Holloway, Robert W. Florida Hospital Gynecologic Oncology, Florida Hospital Cancer Institute, Orlando, FL, USA. robhollowaymd@gmail.com. IN - Ahmad, Sarfraz. Florida Hospital Gynecologic Oncology, Florida Hospital Cancer Institute, Orlando, FL, USA. sarfraz.ahmad@flhosp.org. IN - Kendrick, James E. Florida Hospital Gynecologic Oncology, Florida Hospital Cancer Institute, Orlando, FL, USA. IN - Bigsby, Glenn E. Florida Hospital Gynecologic Oncology, Florida Hospital Cancer Institute, Orlando, FL, USA. IN - Brudie, Lorna A. Florida Hospital Gynecologic Oncology, Florida Hospital Cancer Institute, Orlando, FL, USA. IN - Ghurani, Giselle B. Florida Hospital Gynecologic Oncology, Florida Hospital Cancer Institute, Orlando, FL, USA. IN - Stavitzski, Nicole M. Florida Hospital Gynecologic Oncology, Florida Hospital Cancer Institute, Orlando, FL, USA. IN - Gise, Jasmine L. Florida Hospital Gynecologic Oncology, Florida Hospital Cancer Institute, Orlando, FL, USA. IN - Ingersoll, Susan B. Florida Hospital Gynecologic Oncology, Florida Hospital Cancer Institute, Orlando, FL, USA. IN - Pepe, Julie W. Florida Hospital Gynecologic Oncology, Florida Hospital Cancer Institute, Orlando, FL, USA. TI - A Prospective Cohort Study Comparing Colorimetric and Fluorescent Imaging for Sentinel Lymph Node Mapping in Endometrial Cancer. SO - Annals of Surgical Oncology. , 2017 Mar 06 AS - Ann Surg Oncol. , 2017 Mar 06 NJ - Annals of surgical oncology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - b9r, 9420840 IO - Ann. Surg. Oncol. CP - United States AB - BACKGROUND: This prospective cohort study aimed to assess sentinel lymph node (SLN) mapping using isosulfan blue (ISB) compared with ISB plus indocyanine green (ICG) and near-infrared imaging (NIR) for patients with endometrial cancer. AB - METHODS: In this study, 200 patients with endometrial cancer underwent SLN assessments and were randomized to ISB + ICG (n = 180) or ISB alone (n = 20). Blue dye determinations were recorded for all 200 cases followed by NIR imaging of ICG for 180 randomized subjects. All the patients underwent robotically assisted hysterectomy with pelvic +/- aortic lymphadenectomy. AB - RESULTS: The mean age of the patients was 64.5 +/- 8.4 years, and the mean body mass index (BMI) was 33 +/- 7.6 kg/m². The histologies were endometrioid G1 (43%), G2 (30%), G3 (7%), and type 2 (20%). The mean time from dye injection to initiation of mapping was 13.4 +/- 6.2 min, and the time to removal of SLN was 17.4 +/- 11.2 min. Detection of SLN for the 20 ISB control cases did not differ from that for the 180 ISB + ICG cases (p > 0.05). The rates of SLN detection for ISB + ICG/NIR (n = 180) versus ISB (n = 200) were as follows: bilateral (83.9 vs. 40%), unilateral (12.2 vs. 36%), and none (3.9 vs. 24%) (p < 0.001). The median SLN per case was 2 (range 0-4). Positive SLNs were found in 21.1% (n = 38) of the ISB + ICG cases compared with 13.5% (n = 27) of the ISB cases (p = 0.056). The false-negative rate for SLN biopsy was 2.5% (95% confidence interval, 0.1-14.7%). In 61% (25/41) of the node-positive cases, SLN was the only positive lymph node (LN). Isolated tumor cells were found in 39.5% (15/38) of the SLN metastasis cases compared with 26.7% (4/15) of the non-SLN metastasis cases (p = 0.528). AB - CONCLUSIONS: In this prospective study, ISB + ICG and NIR detected more SLNs and more LN metastases than ISB alone. Assessment of SLN with ICG + ISB/NIR imaging had excellent sensitivity for detection of metastasis and no safety issues. ES - 1534-4681 IL - 1068-9265 DI - 10.1245/s10434-017-5825-3 DO - https://dx.doi.org/10.1245/s10434-017-5825-3 PT - Journal Article ID - 10.1245/s10434-017-5825-3 [doi] ID - 10.1245/s10434-017-5825-3 [pii] PP - aheadofprint PH - 2017/01/11 [received] LG - English EP - 20170306 DP - 2017 Mar 06 DC - 20170307 EZ - 2017/03/08 06:00 DA - 2017/03/08 06:00 DT - 2017/03/08 06:00 YR - 2017 RD - 20170307 UP - 20170309 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=28265777 <751. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28205030 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Lee S AU - Kim JK AU - Kim YN AU - Jang DS AU - Kim YM AU - Son T AU - Hyung WJ AU - Kim HI AI - Kim, Hyoung-Il; ORCID: http://orcid.org/0000-0002-6134-4523 FA - Lee, Seungho FA - Kim, Jin Kyong FA - Kim, Youn Nam FA - Jang, Dong-Su FA - Kim, Yoo Min FA - Son, Taeil FA - Hyung, Woo Jin FA - Kim, Hyoung-Il IN - Lee, Seungho. Department of Surgery, Yonsei University College of Medicine, Yonsei University Health System, 50 Yonsei-ro, Seodaemun-gu, 120-752, Seoul, South Korea. IN - Kim, Jin Kyong. Department of Surgery, Yonsei University College of Medicine, Yonsei University Health System, 50 Yonsei-ro, Seodaemun-gu, 120-752, Seoul, South Korea. IN - Kim, Youn Nam. Department of Biostatistics, Yonsei University College of Medicine, Seoul, South Korea. IN - Jang, Dong-Su. Department of Sculpture, Hongik University, Seoul, South Korea. IN - Kim, Yoo Min. Department of Surgery, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, South Korea. IN - Son, Taeil. Department of Surgery, Yonsei University College of Medicine, Yonsei University Health System, 50 Yonsei-ro, Seodaemun-gu, 120-752, Seoul, South Korea. IN - Hyung, Woo Jin. Department of Surgery, Yonsei University College of Medicine, Yonsei University Health System, 50 Yonsei-ro, Seodaemun-gu, 120-752, Seoul, South Korea. IN - Hyung, Woo Jin. Minimally Invasive Surgery Center, Yonsei University Health System, Seoul, South Korea. IN - Kim, Hyoung-Il. Department of Surgery, Yonsei University College of Medicine, Yonsei University Health System, 50 Yonsei-ro, Seodaemun-gu, 120-752, Seoul, South Korea. cairus@yuhs.ac. IN - Kim, Hyoung-Il. Minimally Invasive Surgery Center, Yonsei University Health System, Seoul, South Korea. cairus@yuhs.ac. IN - Kim, Hyoung-Il. Open NBI Convergence Technology Research Laboratory, Severance Hospital, Yonsei University Health System, Seoul, South Korea. cairus@yuhs.ac. TI - Safety and feasibility of reduced-port robotic distal gastrectomy for gastric cancer: a phase I/II clinical trial. SO - Surgical Endoscopy. , 2017 Feb 15 AS - Surg Endosc. , 2017 Feb 15 NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc CP - Germany AB - INTRODUCTION: Theoretically, reducing the number of ports required in minimally invasive surgery for gastric cancer would further minimize trauma associated therewith. Advances in single-site surgery have afforded surgeons the ability to perform reduced-port distal gastrectomy via a robotic approach using the Single-SiteTM system, eliminating restrictions on the movement of surgical instruments. AB - METHODS: This phase I/II study was designed as a single-arm prospective trial of reduced-port robotic distal gastrectomy (RRDG) by a single surgeon (NCT02347956). From January to October 2015, 40 individuals scheduled to undergo robotic surgery for early gastric cancer were asked to participate in the trial. Nineteen were enrolled and underwent RRDG. The primary endpoints were 30-day morbidity and mortality. AB - RESULTS: No intraoperative event requiring conversion to laparoscopic or open surgery occurred, and no major complication was observed following RRDG (0.0% [80% CI (0.0-11.4%)]). Medians of operation time, blood loss, the number of retrieved lymph nodes, days until gas passing, and hospital stay were 190 min, 20 mL, 48, 3, and 5 days, respectively. AB - CONCLUSIONS: Deemed safe and feasible through the present trial, RRDG could be a valid alternative to conventional robot distal gastrectomy for managing early gastric cancer. Our reduced-port robotic surgery using the Single-Site system and a third robotic arm could potentially be applicable as a highly advanced, minimally invasive surgery for other solid organ diseases. ES - 1432-2218 IL - 0930-2794 DI - 10.1007/s00464-017-5435-y DO - https://dx.doi.org/10.1007/s00464-017-5435-y PT - Journal Article ID - 28205030 [pubmed] ID - 10.1007/s00464-017-5435-y [doi] ID - 10.1007/s00464-017-5435-y [pii] PP - aheadofprint PH - 2016/10/17 [received] PH - 2017/01/20 [accepted] LG - English EP - 20170215 DP - 2017 Feb 15 DC - 20170216 EZ - 2017/02/17 06:00 DA - 2017/02/17 06:00 DT - 2017/02/17 06:00 YR - 2017 RD - 20170216 UP - 20170221 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=28205030 <752. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28043722 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Wijk L AU - Nilsson K AU - Ljungqvist O FA - Wijk, Lena FA - Nilsson, Kerstin FA - Ljungqvist, Olle IN - Wijk, Lena. Department of Obstetrics and Gynaecology, Orebro University Hospital, Sweden; School of Medical Sciences, Faculty of Medicine and Health, Orebro University, Sweden. Electronic address: lena.wijk@oru.se. IN - Nilsson, Kerstin. School of Medical Sciences, Faculty of Medicine and Health, Orebro University, Sweden. Electronic address: kerstin.nilsson.ha@oru.se. IN - Ljungqvist, Olle. School of Medical Sciences, Faculty of Medicine and Health, Orebro University, Sweden; Department of Surgery, Orebro University Hospital, Sweden. Electronic address: olle.ljungqvist@oru.se. TI - Metabolic and inflammatory responses and subsequent recovery in robotic versus abdominal hysterectomy: A randomised controlled study. SO - Clinical Nutrition. , 2016 Dec 23 AS - Clin Nutr. , 2016 Dec 23 NJ - Clinical nutrition (Edinburgh, Scotland) PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - c3x, 8309603 IO - Clin Nutr CP - England KW - Hysterectomy; Inflammatory response; Insulin resistance; Robotic-assisted hysterectomy AB - BACKGROUND & AIMS: Surgery causes inflammatory and metabolic responses in the body. The aim of the study was to investigate whether robotic-assisted total laparoscopic hysterectomy induces less insulin resistance than abdominal hysterectomy, and to compare inflammatory response and clinical recovery between the two techniques. AB - METHODS: A randomised controlled study at the Department of Obstetrics and Gynaecology, Orebro University Hospital, Sweden. Twenty women scheduled for a planned total hysterectomy with or without salpingo-oophorectomy between October 2014 and May 2015, were randomly allocated to robotic-assisted total laparoscopic hysterectomy or abdominal hysterectomy. Insulin resistance after surgery was measured by the hyperinsulinemic normoglycaemic clamp method, inflammatory response measured in blood samples, and clinical recovery outcomes registered. AB - RESULTS: There were no differences in development of insulin resistance between the robotic group and the abdominal group (mean +/- SD: 39% +/- 22 vs. 40% +/- 19; p = 0.948). The robotic group had a significantly shorter hospital stay (median 1 vs. 2 days; p = 0.005). Inflammatory reaction differed; in comparison to the robotic group, the abdominal group showed significantly higher increases in serum interleukin 6 levels, white blood cell count and cortisol from preoperative values to postoperative peak values. AB - CONCLUSIONS: Robotic laparoscopic surgery reduced inflammatory responses and recovery time, but these changes were not accompanied by decreased insulin resistance. AB - CLINICAL TRIAL REGISTRATION: www.ClinicalTrials.gov Identifier no NCT02291406. AB - Copyright © 2016 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved. ES - 1532-1983 IL - 0261-5614 DI - S0261-5614(16)31356-5 DO - https://dx.doi.org/10.1016/j.clnu.2016.12.015 PT - Journal Article ID - 28043722 [pubmed] ID - S0261-5614(16)31356-5 [pii] ID - 10.1016/j.clnu.2016.12.015 [doi] PP - aheadofprint PH - 2016/09/29 [received] PH - 2016/12/14 [revised] PH - 2016/12/19 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT02291406 SL - https://clinicaltrials.gov/search/term=NCT02291406 LG - English EP - 20161223 DP - 2016 Dec 23 DC - 20170103 EZ - 2017/01/04 06:00 DA - 2017/01/04 06:00 DT - 2017/01/04 06:00 YR - 2016 RD - 20170203 UP - 20170206 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=28043722 <753. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27864724 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Kudsi OY AU - Castellanos A AU - Kaza S AU - McCarty J AU - Dickens E AU - Martin D AU - Tiesenga FM AU - Konstantinidis K AU - Hirides P AU - Mehendale S AU - Gonzalez A AI - Kudsi, Omar Yusef; ORCID: http://orcid.org/0000-0001-6723-0909 FA - Kudsi, Omar Yusef FA - Castellanos, Andres FA - Kaza, Srinivas FA - McCarty, Justin FA - Dickens, Eugene FA - Martin, David FA - Tiesenga, Frederick M FA - Konstantinidis, Konstantinos FA - Hirides, Petros FA - Mehendale, Shilpa FA - Gonzalez, Anthony IN - Kudsi, Omar Yusef. Tufts University School of Medicine, Boston, MA, USA. omar.kudsi@tufts.edu. IN - Castellanos, Andres. Drexel University College of Medicine, Philadelphia, PA, USA. IN - Kaza, Srinivas. JFK Medical Center, Lake Worth, FL, USA. IN - McCarty, Justin. St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA. IN - Dickens, Eugene. Hillcrest Medical Center, Tulsa, OK, USA. IN - Martin, David. Huntington Hospital, Pasadena, CA, USA. IN - Tiesenga, Frederick M. West Suburban Medical Center, Oak Park, IL, USA. IN - Konstantinidis, Konstantinos. Athens Medical Center, Athens, Greece. IN - Hirides, Petros. Athens Medical Center, Athens, Greece. IN - Mehendale, Shilpa. Intuitive Surgical Clinical Affairs, Sunnyvale, CA, USA. IN - Gonzalez, Anthony. Baptist Hospital South Florida, Miami, FL, USA. TI - Cosmesis, patient satisfaction, and quality of life after da Vinci Single-Site cholecystectomy and multiport laparoscopic cholecystectomy: short-term results from a prospective, multicenter, randomized, controlled trial. SO - Surgical Endoscopy. , 2016 Nov 18 AS - Surg Endosc. , 2016 Nov 18 NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc CP - Germany KW - Cosmesis; Laparoscopy; Multiport cholecystectomy; Quality of life; Robotic-assisted surgery; Single-port cholecystectomy AB - BACKGROUND: Single-incision laparoscopic cholecystectomy evolved from the traditional multiport laparoscopic technique. Prior trials have demonstrated improved cosmesis with the single-incision technique. Robotic single-site surgery minimizes the technical difficulties associated with laparoscopic single-incision approach. This is the first prospective, randomized, controlled study comparing robotic single-site cholecystectomy (RSSC) and multiport laparoscopic cholecystectomy (MPLC) in terms of cosmesis and patient satisfaction. AB - METHODS: Patients with symptomatic benign gallbladder disease were randomized to RSSC or MPLC. Data included perioperative variables such as operative time, conversion and complications and cosmesis satisfaction, body image perception, quality of life using validated questionnaires, at postoperative visits of 2, 6 weeks and 3 months. AB - RESULTS: One hundred thirty-six patients were randomized to RSSC (N = 83) and MPLC (N = 53) at 8 institutions. Both cohorts were dominated by higher enrollment of females (RSSC = 78%, MPLC = 92%). The RSSC and MPLC cohorts were otherwise statistically matched. Operative time was longer for RSSC (61 min vs. 44 min, P < 0.0001). There were no differences in complication rates. RSSC demonstrated a significant superiority in cosmesis satisfaction and body image perception (P value < 0.05 at every follow-up). There was no statistically significant difference in patient-reported quality of life. Multivariate analysis of female patients demonstrated significantly higher preference for RSSC over MPLC in cosmesis satisfaction and body image perception with no difference seen in overall quality of life. AB - CONCLUSIONS: Results from this trial show that RSSC is associated with improved cosmesis satisfaction and body image perception without a difference in observed complication rate. The uncompromised safety and the improved cosmesis satisfaction and body image perception provided by RSSC for female patients support consideration of the robotic single-site approach. ClinicalTrials.gov identifier NCT01932216. ES - 1432-2218 IL - 0930-2794 DI - 10.1007/s00464-016-5353-4 DO - https://dx.doi.org/10.1007/s00464-016-5353-4 PT - Journal Article ID - 27864724 [pubmed] ID - 10.1007/s00464-016-5353-4 [doi] ID - 10.1007/s00464-016-5353-4 [pii] PP - aheadofprint PH - 2016/08/12 [received] PH - 2016/11/09 [accepted] SI - ClinicalTrials.gov SA - ClinicalTrials.gov/NCT01932216 SL - https://clinicaltrials.gov/search/term=NCT01932216 LG - English EP - 20161118 DP - 2016 Nov 18 DC - 20161119 EZ - 2016/11/20 06:00 DA - 2016/11/20 06:00 DT - 2016/11/20 06:00 YR - 2016 RD - 20170203 UP - 20170206 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=27864724 <754. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28078523 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Cestari A AU - Ferrari M AU - Sangalli M AU - Zanoni M AU - Ghezzi M AU - Fabbri F AU - Sozzi F AU - Lolli C AU - Dell'Acqua V AU - Rigatti P FA - Cestari, Andrea FA - Ferrari, Matteo FA - Sangalli, Mattia FA - Zanoni, Matteo FA - Ghezzi, Massimo FA - Fabbri, Fabio FA - Sozzi, Francesco FA - Lolli, Carolina FA - Dell'Acqua, Vincenzo FA - Rigatti, Patrizio IN - Cestari, Andrea. Department of Urology-Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano", Via Mercalli 30, 20122, Milan, Italy. a.cestari@auxologico.it. IN - Ferrari, Matteo. Department of Urology-Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano", Via Mercalli 30, 20122, Milan, Italy. IN - Sangalli, Mattia. Department of Urology-Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano", Via Mercalli 30, 20122, Milan, Italy. IN - Zanoni, Matteo. Department of Urology-Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano", Via Mercalli 30, 20122, Milan, Italy. IN - Ghezzi, Massimo. Department of Urology-Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano", Via Mercalli 30, 20122, Milan, Italy. IN - Fabbri, Fabio. Department of Urology-Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano", Via Mercalli 30, 20122, Milan, Italy. IN - Sozzi, Francesco. Department of Urology-Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano", Via Mercalli 30, 20122, Milan, Italy. IN - Lolli, Carolina. Department of Urology-Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano", Via Mercalli 30, 20122, Milan, Italy. IN - Dell'Acqua, Vincenzo. Department of Urology-Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano", Via Mercalli 30, 20122, Milan, Italy. IN - Rigatti, Patrizio. Department of Urology-Advanced Urotechnology Center, Scientific Institute "Istituto Auxologico Italiano", Via Mercalli 30, 20122, Milan, Italy. TI - Simple vs six-branches autologous suburethral sling during robot-assisted radical prostatectomy to improve early urinary continence recovery: prospective randomized study. SO - Journal of Robotic Surgery. , 2017 Jan 11 AS - J. robot. surg.. , 2017 Jan 11 NJ - Journal of robotic surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101300401 IO - J Robot Surg CP - England KW - Prostate cancer; Retropubic sling; Robotic radical prostatectomy; Urinary incontinence AB - We have recently described the use of a retropubic suburethral autologous sling created and placed during robotic radical prostatectomy (RARP). In this study, we assess the effectiveness of newly designed six-branches compared to two-branches suburethral autologous sling in improving early urinary continence (UC) recovery. 120 patients submitted to RARP were prospectively randomized according to the intraoperative positioning of six-branches (group 1, n = 60) or two-branches autologous sling (group 2, n = 60) obtained by different configuration of a same tract of vas deferens removed. Early UC recovery was assessed at 5 (catheter removal), 10 and 30 days postoperatively through the daily number of pads used and the International Consultation on Incontinence Questionnaire-Urinary Incontinence-Short Form (ICIQ-UI-SF) score. UC was defined as the non-use of pad. Chi square test and Wilcoxon test were used to investigate UC recovery between the two groups. Moreover, post-voiding residual was evaluated in each patient at the same time. At catheter removal, UC rate was in groups 1 and 2, 60 and 35% (p = 0.02); at 10 days 70 and 46% (p = 0.03); at 30 days 87 and 70% (p = 0.04), respectively. One patient in group 1 experienced acute urinary retention at the time of catheter removal and was treated uneventfully with a further 7-day catheterization. These preliminary data indicate that newly designed six-branches suburethral autologous sling is able to increase the rate of early UC recovery compared to the two-arms sling previously described by us. ES - 1863-2491 IL - 1863-2483 DI - 10.1007/s11701-017-0672-6 DO - https://dx.doi.org/10.1007/s11701-017-0672-6 PT - Journal Article ID - 28078523 [pubmed] ID - 10.1007/s11701-017-0672-6 [doi] ID - 10.1007/s11701-017-0672-6 [pii] PP - aheadofprint PH - 2016/11/21 [received] PH - 2017/01/02 [accepted] LG - English EP - 20170111 DP - 2017 Jan 11 DC - 20170112 EZ - 2017/01/13 06:00 DA - 2017/01/13 06:00 DT - 2017/01/13 06:00 YR - 2017 RD - 20170112 UP - 20170116 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=28078523 <755. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 28000016 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Luciani LG AU - Chiodini S AU - Mattevi D AU - Cai T AU - Puglisi M AU - Mantovani W AU - Malossini G FA - Luciani, Lorenzo G FA - Chiodini, Stefano FA - Mattevi, Daniele FA - Cai, Tommaso FA - Puglisi, Marco FA - Mantovani, William FA - Malossini, Gianni IN - Luciani, Lorenzo G. Department of Urology, Santa Chiara Hospital, Largo Medaglie d'oro 9, 38122, Trento, Italy. lorenzo_luciani@hotmail.com. IN - Chiodini, Stefano. Department of Urology, Santa Chiara Hospital, Largo Medaglie d'oro 9, 38122, Trento, Italy. stefano.chiodini@apss.tn.it. IN - Mattevi, Daniele. Department of Urology, Santa Chiara Hospital, Largo Medaglie d'oro 9, 38122, Trento, Italy. IN - Cai, Tommaso. Department of Urology, Santa Chiara Hospital, Largo Medaglie d'oro 9, 38122, Trento, Italy. IN - Puglisi, Marco. Department of Urology, Santa Chiara Hospital, Largo Medaglie d'oro 9, 38122, Trento, Italy. IN - Mantovani, William. Department of Prevention, Public Health Care Trust, Trento, Italy. IN - Malossini, Gianni. Department of Urology, Santa Chiara Hospital, Largo Medaglie d'oro 9, 38122, Trento, Italy. TI - Robotic-assisted partial nephrectomy provides better operative outcomes as compared to the laparoscopic and open approaches: results from a prospective cohort study. SO - Journal of Robotic Surgery. , 2016 Dec 20 AS - J. robot. surg.. , 2016 Dec 20 NJ - Journal of robotic surgery PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101300401 IO - J Robot Surg CP - England KW - Carcinoma renal cell; Laparoscopy; Nephrectomy; Open; Operative outcomes; Partial; Robotics AB - The objective of this is to compare the surgical outcomes of partial nephrectomy (PN), performed via three different approaches: robot-assisted (RAPN), laparoscopic (LPN), and open (OPN), in a single non-academic regional center. The data of patients undergoing PN at our Department from 2005 to 2016 were prospectively collected. A logistic regression model adjusted for preoperative variables (age, tumor size, creatinine and hemoglobin, ASA and Padua scores) was performed to evaluate whether transfusion, conversion, and postoperative complication rate were influenced by the surgical approach. Overall 270 patients underwent PN: analysis included 253 cases (RAPN = 110, LPN = 70, OPN = 73). Preoperative variables did not differ significantly among the three groups. Shorter operative (130 vs 180 and 200') and ischaemia (12 vs 23 and 22') times and longer hospital stay (8 vs 7 and 6 days) were found in the OPN group as compared to LPN and RAPN, respectively. The RAPN group included a higher rate of pT1b (31.8 vs 14.2 and 15%) and malignant histotype (90 vs 82.9 and 68.5%) as compared to LPN and OPN, respectively. Clavien Grade III-IV complications were lower in the RAPN (7.2%) as compared to OPN (12.3%) and LPN (17.1%) groups. Multivariate analysis showed a lower risk for conversion, transfusion and overall complications in the RAPN group versus LPN and OPN. The surgical approach affects the perioperative outcomes in a regional setting. The advantages of RAPN over OPN (lower risk of conversion, transfusion, and overall complications) are extended over LPN as well, although OPN offered faster operative and ischemia times at the expense of greater blood loss and hospital stay. ES - 1863-2491 IL - 1863-2483 DI - 10.1007/s11701-016-0660-2 DO - https://dx.doi.org/10.1007/s11701-016-0660-2 PT - Journal Article ID - 28000016 [pubmed] ID - 10.1007/s11701-016-0660-2 [doi] ID - 10.1007/s11701-016-0660-2 [pii] PP - aheadofprint PH - 2016/10/06 [received] PH - 2016/12/04 [accepted] LG - English EP - 20161220 DP - 2016 Dec 20 DC - 20161221 EZ - 2016/12/22 06:00 DA - 2016/12/22 06:00 DT - 2016/12/22 06:00 YR - 2016 RD - 20161222 UP - 20161223 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=28000016 <756. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27844235 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Groenman F AU - Nikkels C AU - Huirne J AU - van Trotsenburg M AU - Trum H FA - Groenman, Freek FA - Nikkels, Charlotte FA - Huirne, Judith FA - van Trotsenburg, Mick FA - Trum, Hans IN - Groenman, Freek. Center of Expertise on Gender Dysphoria, VU University Medical Center, Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. f.groenman@vumc.nl. IN - Groenman, Freek. Department of Obstetrics and Gynecology, VU University Medical Center, Amsterdam, The Netherlands. f.groenman@vumc.nl. IN - Nikkels, Charlotte. Department of Obstetrics and Gynecology, VU University Medical Center, Amsterdam, The Netherlands. IN - Huirne, Judith. Department of Obstetrics and Gynecology, VU University Medical Center, Amsterdam, The Netherlands. IN - van Trotsenburg, Mick. Center of Expertise on Gender Dysphoria, VU University Medical Center, Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. IN - van Trotsenburg, Mick. Department of Obstetrics and Gynecology, VU University Medical Center, Amsterdam, The Netherlands. IN - Trum, Hans. Center of Expertise on Gender Dysphoria, VU University Medical Center, Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. TI - Robot-assisted laparoscopic colpectomy in female-to-male transgender patients; technique and outcomes of a prospective cohort study. SO - Surgical Endoscopy. , 2016 Nov 14 AS - Surg Endosc. , 2016 Nov 14 NJ - Surgical endoscopy PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - vbf, 8806653 IO - Surg Endosc CP - Germany KW - Colpectomy; Hysterectomy; Laparoscopy; Robot; Transgender AB - BACKGROUND: Gender-affirming surgeries in female-to-male (FtM) transgender patients include mostly hysterectomy, bilateral salpingo-oophorectomy and mastectomy. Sometimes further surgery is performed, such as phalloplasty. Colpectomy may be performed to overcome gender dysphoria and disturbing vaginal discharge; furthermore, it may be important in reducing the risk of fistulas due to the phalloplasty procedure with urethral elongation. Colpectomy prior to the reconstruction of the neourethra seems to reduce fistula rates on the very first anastomosis. Therefore, at our center, colpectomy has become a standard procedure prior to phalloplasty and metoidioplasty with urethral elongation. Colpectomy is known as a procedure with potentially serious complications, e.g., extensive bloodloss, vesicovaginal fistula or rectovaginal fistula. Colpectomy performed via the vaginal route can be a challenging procedure due to lack of exposure of the surgical field, as many patients are virginal. Therefore, we investigated whether robot-assisted laparoscopic hysterectomy with bilateral salpingo-oophorectomy (TLH-BSO) followed by robot-assisted laparoscopic colpectomy (RaLC) is an alternative for the vaginal approach. AB - METHODS: Robot TLH/BSO and RaLC as a single-step procedure was performed in 36 FtM patients in a prospective cohort study. AB - RESULTS: Median length of the procedure was 230 min (197-278), which reduced in the second half of the patients, median blood loss was 75 mL (30-200), and median discharge was 3 days (2-3) postoperatively. One patient with a major complication (postoperative bleeding with readmission and transfusion) was reported. AB - CONCLUSION: To our knowledge, this is the first report of RaLC. Our results show that RaLC combined with robot TLH-BSO is feasible as a single-step surgical procedure in FtM transgender surgery. Future studies are needed to compare this technique to the two-step surgical approach and on its outcome and complication rates of subsequent phalloplasty. ES - 1432-2218 IL - 0930-2794 DI - 10.1007/s00464-016-5333-8 DO - https://dx.doi.org/10.1007/s00464-016-5333-8 PT - Journal Article ID - 27844235 [pubmed] ID - 10.1007/s00464-016-5333-8 [doi] ID - 10.1007/s00464-016-5333-8 [pii] PP - aheadofprint PH - 2016/05/17 [received] PH - 2016/10/31 [accepted] LG - English EP - 20161114 DP - 2016 Nov 14 DC - 20161115 EZ - 2016/11/16 06:00 DA - 2016/11/16 06:00 DT - 2016/11/16 06:00 YR - 2016 RD - 20161116 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=27844235 <757. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27306985 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Todesca A AU - Garro L AU - Penna M AU - Bejui-Hugues J FA - Todesca, Alessandro FA - Garro, Luca FA - Penna, Massimo FA - Bejui-Hugues, Jacques IN - Todesca, Alessandro. Department of Orthopaedic Surgery, Istituto Chirurgico Ortopedico Traumatologico (ICOT), Latina, Italy. IN - Garro, Luca. Department of Orthopaedics and Traumatology, University of Rome Tor Vergata, Rome, Italy. garro.luca@gmail.com. IN - Penna, Massimo. Department of Orthopaedic Surgery, Istituto Chirurgico Ortopedico Traumatologico (ICOT), Latina, Italy. IN - Bejui-Hugues, Jacques. Department of Orthopaedic Surgery, Istituto Chirurgico Ortopedico Traumatologico (ICOT), Latina, Italy. TI - Conventional versus computer-navigated TKA: a prospective randomized study. SO - Knee Surgery, Sports Traumatology, Arthroscopy. , 2016 Jun 15 AS - Knee Surg Sports Traumatol Arthrosc. , 2016 Jun 15 NJ - Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - cch, 9314730 IO - Knee Surg Sports Traumatol Arthrosc CP - Germany KW - Computer navigation; Computer-assisted surgery; Implant alignment; Implant survival; Knee prosthesis; Knee replacement; Knee surgery; Mechanical axis; Soft-tissue balancing; Total knee arthroplasty AB - PURPOSE: The purpose of this study was to assess the midterm results of total knee arthroplasty (TKA) implanted with a specific computer navigation system in a group of patients (NAV) and to assess the same prosthesis implanted with the conventional technique in another group (CON); we hypothesized that computer navigation surgery would improve implant alignment, functional scores and survival of the implant compared to the conventional technique. AB - METHODS: From 2008 to 2009, 225 patients were enrolled in the study and randomly assigned in CON and NAV groups; 240 consecutive mobile-bearing ultra-congruent score (Amplitude, Valence, France) TKAs were performed by a single surgeon, 117 using the conventional method and 123 using the computer-navigated approach. Clinical outcome assessment was based on the Knee Society Score (KSS), the Hospital for Special Surgery Knee Score and the Western Ontario Mac Master University Index score. Component survival was calculated by Kaplan-Meier analysis. AB - RESULTS: Median follow-up was 6.4 years (range 6-7 years). Two patients were lost to follow-up. No differences were seen between the two groups in age, sex, BMI and side of implantation. Three patients of CON group referred feelings of instability during walking, but clinical tests were all negative. NAV group showed statistical significant better KSS Score and wider ROM and fewer outliers from neutral mechanical axis, lateral distal femoral angle, medial proximal tibial angle and tibial slope in post-operative radiographic assessment. There was one case of early post-operative superficial infection (caused by Staph. Aureus) successfully treated with antibiotics. No mechanical loosening, mobile-bearing dislocation or patellofemoral complication was seen. At 7 years of follow-up, component survival in relation to the risk of aseptic loosening or other complications was 100 %. There were no implant revisions. AB - CONCLUSION: This study demonstrates superior accuracy in implant positioning and statistical significant better functional outcomes of computer-navigated TKA. Computer navigation for TKAs should be used routinely in primary implants. AB - LEVEL OF EVIDENCE: II. ES - 1433-7347 IL - 0942-2056 DI - 10.1007/s00167-016-4196-9 DO - https://dx.doi.org/10.1007/s00167-016-4196-9 PT - Journal Article ID - 27306985 [pubmed] ID - 10.1007/s00167-016-4196-9 [doi] ID - 10.1007/s00167-016-4196-9 [pii] PP - aheadofprint PH - 2015/09/26 [received] PH - 2016/06/07 [accepted] LG - English EP - 20160615 DP - 2016 Jun 15 DC - 20160616 EZ - 2016/06/17 06:00 DA - 2016/06/17 06:00 DT - 2016/06/17 06:00 YR - 2016 RD - 20160616 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=27306985 <758. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27679314 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Deimling TA AU - Eldridge JL AU - Riley KA AU - Kunselman AR AU - Harkins GJ FA - Deimling, T A FA - Eldridge, J L FA - Riley, K A FA - Kunselman, A R FA - Harkins, G J IN - Deimling, T A. Obstetrics and Gynecology, The Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania. IN - Eldridge, J L. Obstetrics and Gynecology, The Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania. IN - Riley, K A. Obstetrics and Gynecology, The Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania. IN - Kunselman, A R. Public Health Sciences, The Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania. IN - Harkins, G J. Obstetrics and Gynecology, The Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania. TI - Standard Versus Robot-Assisted Laparoscopic Hysterectomy: A Prospective Randomized Trial. SO - Journal of Minimally Invasive Gynecology. 22(6S):S7-S8, 2015 Nov-Dec AS - J Minim Invasive Gynecol. 22(6S):S7-S8, 2015 Nov-Dec NJ - Journal of minimally invasive gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101235322 IO - J Minim Invasive Gynecol CP - United States ES - 1553-4669 IL - 1553-4650 DI - S1553-4650(15)00637-8 DO - https://dx.doi.org/10.1016/j.jmig.2015.08.029 PT - Journal Article ID - 27679314 [pubmed] ID - S1553-4650(15)00637-8 [pii] ID - 10.1016/j.jmig.2015.08.029 [doi] PP - ppublish LG - English EP - 20151015 DP - 2015 Nov-Dec DC - 20160928 EZ - 2016/09/29 06:00 DA - 2016/09/30 06:00 DT - 2016/09/30 06:00 YR - 2015 RD - 20160928 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=27679314 <759. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27679312 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Sangha R FA - Sangha, R IN - Sangha, R. Department of Obstetrics and Gynecology, Henry Ford Hospital, Detroit, Michigan. TI - Preoperative Uterine Volume: Does It Predict Symptomatic Fibroid Recurrence After Robotic Myomectomy: A Retrospective Cohort Study. SO - Journal of Minimally Invasive Gynecology. 22(6S):S68, 2015 Nov-Dec AS - J Minim Invasive Gynecol. 22(6S):S68, 2015 Nov-Dec NJ - Journal of minimally invasive gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101235322 IO - J Minim Invasive Gynecol CP - United States ES - 1553-4669 IL - 1553-4650 DI - S1553-4650(15)00791-8 DO - https://dx.doi.org/10.1016/j.jmig.2015.08.183 PT - Journal Article ID - 27679312 [pubmed] ID - S1553-4650(15)00791-8 [pii] ID - 10.1016/j.jmig.2015.08.183 [doi] PP - ppublish LG - English EP - 20151015 DP - 2015 Nov-Dec DC - 20160928 EZ - 2016/09/29 06:00 DA - 2016/09/30 06:00 DT - 2016/09/30 06:00 YR - 2015 RD - 20160928 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=27679312 <760. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27679220 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Mohling SI AU - Elkattah R AU - Furr RS AU - Widelock T AU - Yilmaz A AU - Boren T AU - Depasquale S FA - Mohling, S I FA - Elkattah, R FA - Furr, R S FA - Widelock, T FA - Yilmaz, A FA - Boren, T FA - Depasquale, S TI - Comparison of Laparoscopically Assisted Transversus Abdominis Plane Block Using Liposomal Bupivacaine With Pre-Incisional Bupivacaine for Post-Operative Pain Control in Patients Undergoing Laparoscopic or Robotic-Assisted Laparoscopic Hysterectomy: A Randomized Controlled Trial. SO - Journal of Minimally Invasive Gynecology. 22(6S):S36, 2015 Nov-Dec AS - J Minim Invasive Gynecol. 22(6S):S36, 2015 Nov-Dec NJ - Journal of minimally invasive gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101235322 IO - J Minim Invasive Gynecol CP - United States ES - 1553-4669 IL - 1553-4650 DI - S1553-4650(15)00707-4 DO - https://dx.doi.org/10.1016/j.jmig.2015.08.099 PT - Journal Article ID - 27679220 [pubmed] ID - S1553-4650(15)00707-4 [pii] ID - 10.1016/j.jmig.2015.08.099 [doi] PP - ppublish LG - English EP - 20151015 DP - 2015 Nov-Dec DC - 20160928 EZ - 2016/09/29 06:00 DA - 2016/09/30 06:00 DT - 2016/09/30 06:00 YR - 2015 RD - 20160928 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=27679220 <761. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27679212 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Chen C AU - Tanner E AU - Malpani A AU - Vedula SS AU - Fader AN AU - Scheib SA AU - Green IC AU - Hager GD FA - Chen, Ccg FA - Tanner, E FA - Malpani, A FA - Vedula, S S FA - Fader, A N FA - Scheib, S A FA - Green, I C FA - Hager, G D IN - Chen, Ccg. Gynob, Johns Hopkins, Baltimore, Maryland. IN - Tanner, E. Gynob, Johns Hopkins, Baltimore, Maryland. IN - Malpani, A. Computer Science, Johns Hopkins University, Baltimore, Maryland. IN - Vedula, S S. Computer Science, Johns Hopkins University, Baltimore, Maryland. IN - Fader, A N. Gynob, Johns Hopkins, Baltimore, Maryland. IN - Scheib, S A. Gynob, Johns Hopkins, Baltimore, Maryland. IN - Green, I C. Gynob, Johns Hopkins, Baltimore, Maryland. IN - Hager, G D. Computer Science, Johns Hopkins University, Baltimore, Maryland. TI - Warm-Up Before Robotic Hysterectomy Does Not Improve Trainee Operative Performance: A Randomized Trial. SO - Journal of Minimally Invasive Gynecology. 22(6S):S34, 2015 Nov-Dec AS - J Minim Invasive Gynecol. 22(6S):S34, 2015 Nov-Dec NJ - Journal of minimally invasive gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101235322 IO - J Minim Invasive Gynecol CP - United States ES - 1553-4669 IL - 1553-4650 DI - S1553-4650(15)00701-3 DO - https://dx.doi.org/10.1016/j.jmig.2015.08.093 PT - Journal Article ID - 27679212 [pubmed] ID - S1553-4650(15)00701-3 [pii] ID - 10.1016/j.jmig.2015.08.093 [doi] PP - ppublish LG - English EP - 20151015 DP - 2015 Nov-Dec DC - 20160928 EZ - 2016/09/29 06:00 DA - 2016/09/30 06:00 DT - 2016/09/30 06:00 YR - 2015 RD - 20160928 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=27679212 <762. > VN - Ovid Technologies DB - Ovid MEDLINE(R) UI - 27679157 RO - From MEDLINE, a database of the U.S. National Library of Medicine. ST - Publisher AU - Choussein S AU - Srouji SS AU - Missmer SA AU - Farland LV AU - Gargiulo AR FA - Choussein, S FA - Srouji, S S FA - Missmer, S A FA - Farland, L V FA - Gargiulo, A R IN - Choussein, S. Center for Infertility and Reproductive Surgery, Department of Obstetrics & Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. IN - Srouji, S S. Center for Infertility and Reproductive Surgery, Department of Obstetrics & Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. IN - Missmer, S A. Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts. IN - Farland, L V. Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts. IN - Gargiulo, A R. Center for Infertility and Reproductive Surgery, Department of Obstetrics & Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. TI - Pregnancy Outcomes and Symptom Relief Following Robot-Assisted Laparoscopic Myomectomy (RALM): A Patient Survey Study With Clinical Correlation. SO - Journal of Minimally Invasive Gynecology. 22(6S):S240, 2015 Nov-Dec AS - J Minim Invasive Gynecol. 22(6S):S240, 2015 Nov-Dec NJ - Journal of minimally invasive gynecology PI - Journal available in: Print-Electronic PI - Citation processed from: Internet JC - 101235322 IO - J Minim Invasive Gynecol CP - United States ES - 1553-4669 IL - 1553-4650 DI - S1553-4650(15)01451-X DO - https://dx.doi.org/10.1016/j.jmig.2015.08.843 PT - Journal Article ID - 27679157 [pubmed] ID - S1553-4650(15)01451-X [pii] ID - 10.1016/j.jmig.2015.08.843 [doi] PP - ppublish LG - English EP - 20151015 DP - 2015 Nov-Dec DC - 20160928 EZ - 2016/09/29 06:00 DA - 2016/09/30 06:00 DT - 2016/09/30 06:00 YR - 2015 RD - 20160928 UP - 20161215 XL - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=27679157