TY  - JOUR
ID  - 105971047
T1  - [Commentary on] Cardiopulmonary exercise testing determination of functional capacity in mitral regurgitation: physiologic and outcome implications.
AU  - Bach DS
Y1  - 2006/08//2006 Aug
N1  - Accession Number: 105971047. Language: English. Entry Date: 20080215. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Original Study: Messika-Zeitoun D, Johnson BD, Nkomo V, Avierinos JF, Allison TG, Scott C, et al. Cardiopulmonary exercise testing determination of functional capacity in mitral regurgitation: physiologic and outcome implications. (J AM COLL CARDIOL) Jun2006; 47 (12): 2521-2527. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 101265145. 
KW  - Exercise Test, Cardiopulmonary
KW  - Mitral Valve Insufficiency -- Prognosis
KW  - Outcomes Research
KW  - Atrial Fibrillation
KW  - Early Intervention
KW  - Echocardiography
KW  - Functional Status
KW  - Morbidity
KW  - Mortality
KW  - Univariate Statistics
SP  - 61
EP  - 61
JO  - ACC Cardiosource Review Journal
JF  - ACC Cardiosource Review Journal
JA  - ACC CARDIOSOURCE REV J
VL  - 15
IS  - 8
CY  - New York, New York
PB  - Elsevier Science
SN  - 1556-8571
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105971047&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105988063
T1  - [Commentary on] Four-year efficacy of cardiac resynchronization therapy on exercise tolerance and disease progression: the importance of performing atrioventricular junction ablation in patients with atrial fibrillation.
AU  - Morady F
Y1  - 2006/10//2006 Oct
N1  - Accession Number: 105988063. Language: English. Entry Date: 20080222. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Original Study: Gasparini M, Auricchio A, Regoli F, Fantoni C, Kawabata M, Galimberti P, et al. Four-year efficacy of cardiac resynchronization therapy on exercise tolerance and disease progression the importance of performing atrioventricular junction ablation in patients with atrial fibrillation. (J AM COLL CARDIOL) Aug2006; 48 (4): 734-743. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 101265145. 
KW  - Atrial Fibrillation -- Surgery
KW  - Catheter Ablation
KW  - Exercise Tolerance
KW  - Cardiac Resynchronization Therapy
KW  - Echocardiography
SP  - 3
EP  - 3
JO  - ACC Cardiosource Review Journal
JF  - ACC Cardiosource Review Journal
JA  - ACC CARDIOSOURCE REV J
VL  - 15
IS  - 10
CY  - New York, New York
PB  - Elsevier Science
SN  - 1556-8571
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105988063&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105812323
T1  - [Commentary on] Long-term effects of cardiac resynchronisation therapy in patients with atrial fibrillation.
AU  - Morady F
Y1  - 2008/08//2008 Aug
N1  - Accession Number: 105812323. Language: English. Entry Date: 20080912. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Original Study: Khadjooi K, Foley PW, Chalil S, Anthony J, Smith REA, Frenneaux MP, et al. Long-term effects of cardiac resynchronisation therapy in patients with atrial fibrillation. (HEART) Jul2008; 94 (7): 879-883. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Critical Care. NLM UID: 101265145. 
KW  - Atrial Fibrillation
KW  - Defibrillation
KW  - Outcomes Research
KW  - Aged
KW  - American Heart Association
KW  - Heart Failure
KW  - Nonexperimental Studies
KW  - Pacemaker, Artificial
KW  - Prospective Studies
KW  - Quality of Life
KW  - Ventricular Ejection Fraction
KW  - Walking
SP  - 4
EP  - 4
JO  - ACC Cardiosource Review Journal
JF  - ACC Cardiosource Review Journal
JA  - ACC CARDIOSOURCE REV J
VL  - 17
IS  - 8
CY  - New York, New York
PB  - Elsevier Science
SN  - 1556-8571
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105812323&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106345863
T1  - [Commentary on] Overweight and obesity as risk factors for atrial fibrillation or flutter: the Danish Diet, Cancer, and Health Study.
AU  - Morady F
Y1  - 2005/09//
N1  - Accession Number: 106345863. Language: English. Entry Date: 20061013. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Original Study: Frost L, Hune LJ, Vestergaard P. Overweight and obesity as risk factors for atrial fibrillation or flutter: the Danish Diet, Cancer, and Health Study. AM J MED 2005; 118: 489-95. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9302140. 
KW  - Atrial Fibrillation -- Risk Factors
KW  - Atrial Flutter -- Risk Factors
KW  - Diet
KW  - Health Status
KW  - Neoplasms
KW  - Obesity
KW  - Body Mass Index
KW  - Denmark
KW  - Female
KW  - Middle Age
SP  - 52
EP  - 52
JO  - ACC Current Journal Review
JF  - ACC Current Journal Review
JA  - ACC CURR J REV
VL  - 14
IS  - 9
CY  - New York, New York
PB  - Elsevier Science
SN  - 1062-1458
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106345863&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105709733
T1  - [Commentary on] Permanent atrial fibrillation affects exercise capacity in chronic heart failure patients.
AU  - Morady F
Y1  - 2008/10//2008 Oct
N1  - Accession Number: 105709733. Language: English. Entry Date: 20081212. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Critical Care. NLM UID: 101265145. 
KW  - Atrial Fibrillation -- Complications
KW  - Exercise Tolerance
KW  - Heart Failure
KW  - Exercise Test, Cardiopulmonary
KW  - Oxygen Consumption
KW  - Retrospective Design
KW  - Ventricular Ejection Fraction
SP  - 33
EP  - 33
JO  - ACC Cardiosource Review Journal
JF  - ACC Cardiosource Review Journal
JA  - ACC CARDIOSOURCE REV J
VL  - 17
IS  - 10
CY  - New York, New York
PB  - Elsevier Science
SN  - 1556-8571
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105709733&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105676647
T1  - [Commentary on] Permanent atrial fibrillation affects exercise capacity in chronic heart failure patients.
AU  - Morady F
Y1  - 2008/09//2008 Sep
N1  - Accession Number: 105676647. Language: English. Entry Date: 20081031. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Original Study: Agostoni P, Emdin M, Corra U, et al. Permanent atrial fibrillation affects exercise capacity in chronic heart failure patients. EUR HEART J 2008 Aug 5. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Critical Care. NLM UID: 101265145. 
KW  - Atrial Fibrillation -- Complications
KW  - Exercise
KW  - Exercise Test, Cardiopulmonary
KW  - Heart Failure
KW  - Oxygenation
KW  - Retrospective Design
KW  - Ventricular Ejection Fraction
SP  - 5
EP  - 5
JO  - ACC Cardiosource Review Journal
JF  - ACC Cardiosource Review Journal
JA  - ACC CARDIOSOURCE REV J
VL  - 17
IS  - 9
CY  - New York, New York
PB  - Elsevier Science
SN  - 1556-8571
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105676647&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105902306
T1  - [Commentary on] Prognostic value of exercise tolerance testing in asymptomatic chronic nonischemic mitral regurgitation.
AU  - Bach DS
Y1  - 2007/12//2007 Dec
N1  - Accession Number: 105902306. Language: English. Entry Date: 20080502. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Original Study: Supino PG, Borer JS, Schuleri K, et al. Prognostic value of exercise tolerance testing in asymptomatic chronic nonischemic mitral regurgitation. Am J Cardiol 2007; 100: 1274-81. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Critical Care. NLM UID: 101265145. 
KW  - Exercise Test
KW  - Mitral Valve Insufficiency -- Prognosis
KW  - American Heart Association
KW  - Atrial Fibrillation
KW  - Death, Sudden
KW  - Heart Failure
KW  - Multivariate Analysis
KW  - Relative Risk
KW  - ST Segment
KW  - Univariate Statistics
KW  - Ventricular Ejection Fraction
SP  - 52
EP  - 52
JO  - ACC Cardiosource Review Journal
JF  - ACC Cardiosource Review Journal
JA  - ACC CARDIOSOURCE REV J
VL  - 16
IS  - 12
CY  - New York, New York
PB  - Elsevier Science
SN  - 1556-8571
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105902306&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106359004
T1  - [Commentary on] Pulmonary hemodynamics at rest and during exercise in patients with significant pulmonary vein stenosis after radiofrequency catheter ablation for drug-resistant atrial fibrillation.
AU  - Morady F
Y1  - 2005/11//
N1  - Accession Number: 106359004. Language: English. Entry Date: 20061110. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Original Study: Arentz T, Weber R, Jander N et al. Pulmonary hemodynamics at rest and during exercise in patients with significant pulmonary vein stenosis after radiofrequency catheter ablation for drug-resistant atrial fibrillation. EUR HEART J 2005; 26: 1410-4. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9302140. 
KW  - Atrial Fibrillation -- Therapy
KW  - Catheter Ablation
KW  - Constriction, Pathologic -- Physiopathology
KW  - Exercise Test
KW  - Hemodynamics
KW  - Pulmonary Veins -- Physiopathology
KW  - Treatment Failure
KW  - Middle Age
SP  - 51
EP  - 52
JO  - ACC Current Journal Review
JF  - ACC Current Journal Review
JA  - ACC CURR J REV
VL  - 14
IS  - 11
CY  - New York, New York
PB  - Elsevier Science
SN  - 1062-1458
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106359004&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105590751
T1  - [Commentary on] Pulmonary-vein isolation for atrial fibrillation in patients with heart failure.
AU  - Morady F
Y1  - 2008/11//2008 Nov
N1  - Accession Number: 105590751. Language: English. Entry Date: 20090130. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Original Study: Khan MN, Jaïs P, Cummings J, Di Biase L, Sanders P, Martin DO, et al. Pulmonary-vein isolation for atrial fibrillation in patients with heart failure. (N ENGL J MED) 10/23/2008; 359 (17): 1778-1785. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Critical Care. NLM UID: 101265145. 
KW  - Atrial Fibrillation
KW  - Catheter Ablation
KW  - Heart Failure
KW  - Pulmonary Veins
KW  - Quality of Life
KW  - Clinical Trials
KW  - Defibrillators, Implantable
KW  - Middle Age
KW  - Questionnaires
KW  - Random Assignment
KW  - Ventricular Ejection Fraction
KW  - Walking
SP  - 2
EP  - 2
JO  - ACC Cardiosource Review Journal
JF  - ACC Cardiosource Review Journal
JA  - ACC CARDIOSOURCE REV J
VL  - 17
IS  - 11
CY  - New York, New York
PB  - Elsevier Science
SN  - 1556-8571
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105590751&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106266717
T1  - [Commentary on] Quality of life and exercise performance in patients in sinus rhythm versus persistent atrial fibrillation.
AU  - Laing ST
Y1  - 2006/11//2006 Nov-Dec
N1  - Accession Number: 106266717. Language: English. Entry Date: 20070413. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Original Study: Singh SN, Tang C, Singh BN, Dorian P, Reda DJ, Harris CL, et al. Quality of life and exercise performance in patients in sinus rhythm versus persistent artrial fibrillation. J Am Coll Cardiol 2006; 48: 721-30. Journal Subset: Allied Health; Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Physical Therapy. NLM UID: 8511296. 
KW  - Atrial Fibrillation -- Complications
KW  - Exercise
KW  - Quality of Life -- Evaluation
SP  - 410
EP  - 411
JO  - Journal of Cardiopulmonary Rehabilitation
JF  - Journal of Cardiopulmonary Rehabilitation
JA  - J CARDIOPULM REHABIL
VL  - 26
IS  - 6
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
SN  - 0883-9212
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106266717&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105937186
T1  - [Commentary on] Quality of life and exercise performance in patients in sinus rhythm versus persistent atrial fibrillation: a Veterans Affairs Cooperative Studies Program substudy.
AU  - Morady F
Y1  - 2006/12/02/2006 Winter Special Edition
N1  - Accession Number: 105937186. Language: English. Entry Date: 20080125. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Supplement Title: 2006 Winter Special Edition. Original Study: Singh SN, Tang XC, Singh BN, et al, on behalf of the SAFE-T Investigators. Quality of life and exercise performance in patients in sinus rhythm versus persistent atrial fibrillation: a Veterans Affairs Cooperative Studies Program substudy. J Am Coll Cardiol 2006; 48: 721-30. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Critical Care. Instrumentation: Short Form-36 Health Survey (SF-36). NLM UID: 101265145. 
KW  - Atrial Fibrillation -- Complications
KW  - Quality of Life
KW  - Clinical Assessment Tools
KW  - Clinical Trials
KW  - Exercise Test, Cardiopulmonary
KW  - Short Form-36 Health Survey (SF-36)
KW  - United States Department of Veterans Affairs
SP  - 59
EP  - 59
JO  - ACC Cardiosource Review Journal
JF  - ACC Cardiosource Review Journal
JA  - ACC CARDIOSOURCE REV J
CY  - New York, New York
PB  - Elsevier Science
SN  - 1556-8571
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105937186&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105988064
T1  - [Commentary on] Quality of life and exercise performance in patients in sinus rhythm verus persistent atrial fibrillation: a Veterans Affairs Cooperative Studies Program substudy.
AU  - Morady F
Y1  - 2006/10//2006 Oct
N1  - Accession Number: 105988064. Language: English. Entry Date: 20080222. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Original Study: Singh SN, Tang XC, Singh BN, Dorian P, Reda DJ, Harris CL, et al. Quality of life and exercise performance in patients in sinus rhythm versus persistent atrial fibrillation a veterans affairs cooperative studies program substudy. (J AM COLL CARDIOL) Aug2006; 48 (4): 721-730. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Critical Care. Instrumentation: Short Form-36 Health Survey (SF-36). NLM UID: 101265145. 
KW  - Atrial Fibrillation
KW  - Exercise Tolerance
KW  - Quality of Life
KW  - Aged
KW  - Amiodarone -- Administration and Dosage
KW  - Clinical Assessment Tools
KW  - Clinical Trials
KW  - Exercise Test, Cardiopulmonary
KW  - Placebos
KW  - Random Assignment
KW  - Short Form-36 Health Survey (SF-36)
KW  - Sotalol -- Administration and Dosage
KW  - United States Department of Veterans Affairs
SP  - 2
EP  - 2
JO  - ACC Cardiosource Review Journal
JF  - ACC Cardiosource Review Journal
JA  - ACC CARDIOSOURCE REV J
VL  - 15
IS  - 10
CY  - New York, New York
PB  - Elsevier Science
SN  - 1556-8571
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105988064&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 116987919
T1  - 197 - Exercise Training in Patients with Chronic Heart Failure and Atrial Fibrillation: Results from the HF-ACTION Trial.
AU  - Luo, Nancy
AU  - Merrill, Peter
AU  - Whellan, David J.
AU  - Pina, Ileana L.
AU  - Fiuzat, Mona
AU  - Kraus, William E.
AU  - Kitzman, Dalane W.
AU  - Keteyian, Steven J.
AU  - O'Connor, Christopher M.
AU  - Mentz, Robert J.
Y1  - 2016/08/02/Aug2016 Supplement
N1  - Accession Number: 116987919. Language: English. Entry Date: In Process. Revision Date: 20160726. Publication Type: Article. Supplement Title: Aug2016 Supplement. Journal Subset: Biomedical; Double Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9442138. 
SP  - S71
EP  - S71
JO  - Journal of Cardiac Failure
JF  - Journal of Cardiac Failure
JA  - J CARD FAIL
VL  - 22
CY  - Philadelphia, Pennsylvania
PB  - W B Saunders
SN  - 1071-9164
AD  - Duke Clinical Research Institute, Durham, NC
AD  - Duke University Medical Center, Durham, NC
AD  - Thomas Jefferson University, Phhiladelphia, PA
AD  - Montefiore-Einstein Medical Center, New York, NY
AD  - Wake Forest School of Medicine, Winston Salem, NC
AD  - Henry Ford Hospital, Detroit, MI
AD  - Inova Heart and Vascular Institute, Falls Church, VA
DO  - 10.1016/j.cardfail.2016.06.225
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=116987919&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105625546
T1  - 2008 late-breaking clinical trial abstracts.
Y1  - 2008/11/25/
N1  - Accession Number: 105625546. Language: English. Entry Date: 20090130. Revision Date: 20150711. Publication Type: Journal Article; abstract; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Critical Care; Perioperative Care. NLM UID: 0147763. 
KW  - Atrial Fibrillation -- Therapy
KW  - Electrophysiology
KW  - Exercise
KW  - Heart Failure -- Therapy
KW  - Stents -- Evaluation
KW  - Arteriosclerosis -- Prevention and Control
KW  - Congresses and Conferences
SP  - 2309
EP  - 2317
JO  - Circulation
JF  - Circulation
JA  - CIRCULATION
VL  - 118
IS  - 22
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
SN  - 0009-7322
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105625546&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109585329
T1  - 5A.04: AN INCREASED VAGAL TONUS IS CRITICAL FOR THE INDUCTION AND MAINTENANCE OF ATRIAL FIBRILLATION IN A SYMPATHOEXCITATORY BACKGROUND AS METABOLIC SYNDROME.
AU  - Goncalves-Rosa, N
AU  - Tavares, C
AU  - Nunes-Da-Silva, C
AU  - Geraldes, V
AU  - Rocha, I
Y1  - 2015/06/02/2015 Supplement 1
N1  - Accession Number: 109585329. Language: English. Entry Date: 20150923. Revision Date: 20160303. Publication Type: journal article. Supplement Title: 2015 Supplement 1. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 8306882. 
SP  - e65
EP  - e65
JO  - Journal of Hypertension
JF  - Journal of Hypertension
JA  - J HYPERTENS
VL  - 33
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - Objective: Evaluate the effects of acute vagal stimulation on atrial conduction, atria and pulmonary veins (PV) refractoriness and AFib inducibility in a MetS rabbit model.Design and Method: MetS was induced in male NZW rabbits, 8 weeks, by a high sucrose diet given for 6 months, after which, under anaesthesia, a thoracotomy was performed to expose the heart. An array of 5 microelectrodes was placed in PV vicinity and in the atrial epicardium to record cardiac electrograms. The right vagus nerve was prepared for electrical stimulation (1ms, 50 Hz, ∼100 μA). ECG electrodes were placed in 3 of the 4 limbs. The epicardial recordings were made in sinus rhythm. Stimulation bursts (10 s, 50 Hz) were used, alone or combined with vagal stimulation, in the right atrial appendage, left atrial appendage and PV to evaluate AFib inducibility. The effective refractory periods (ERP) and conduction times from the high-lateral right atrium to the high-lateral left atrium and PV were quantified before and after vagal stimulation. Heart rate variability using Fast Fourier Transform (FFT) was applied on autonomic evaluation. A control group matching age and sex was used.Results: AFib inducibility was greater in MetS-rabbits with a 50 Hz pacing (38 ± 7% vs 21 ± 7%) and after vagal stimulation (53 ± 6% vs 33 ± 4%). The evoked AFib duration was longer in MetS rabbits than in controls and increased significantly after vagal stimulation. ERPs were lower in MetS rabbits and decreased at all evaluated sites during vagal stimulation. MetS-rabbits had an higher interatrial conduction time than controls (22 ± 1 vs 11 ± 1ms, p < 0.05). FFT analysis confirmed a sympathoexcitatory condition in MetS comparing to controls (0.40 ± 0.09 vs 0.11 ± 0.06mmHg2, p < 0.05).Conclusions: Despite MetS-rabbits have an increased basal sympathetic activity which favoured AFib induction, a simultaneous increased vagal tonus seems to be critical not only for the inducibility but also for the maintenance of AFib in this animal model of MetS.
SN  - 0263-6352
U2  - PMID: 26102886.
DO  - 10.1097/01.hjh.0000467520.36510.9f
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109585329&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 115878394
T1  - 61-Year-Old Man With Chronic Diarrhea.
AU  - Podboy, Alexander
AU  - Anderson, Bradley W
AU  - Sweetser, Seth
Y1  - 2016/02//
N1  - Accession Number: 115878394. Language: English. Entry Date: 20160618. Revision Date: 20160618. Publication Type: journal article. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 0405543. 
KW  - Diarrhea -- Etiology
KW  - Liver Transplantation -- Methods
KW  - Diarrhea -- Therapy
KW  - Diarrhea -- Diagnosis
KW  - Diet, Fat-Restricted -- Methods
KW  - Antidiarrheals -- Therapeutic Use
KW  - Diarrhea -- Physiopathology
KW  - Carpal Tunnel Syndrome -- Etiology
KW  - Amyloid Neuropathies, Familial -- Physiopathology
KW  - Atrial Fibrillation -- Etiology
KW  - Antiinflammatory Agents, Non-Steroidal -- Therapeutic Use
KW  - Amyloid Neuropathies, Familial -- Diagnosis
KW  - Amyloid Neuropathies, Familial -- Complications
KW  - Celiac Disease -- Therapy
KW  - Middle Age
KW  - Biopsy -- Methods
KW  - Mass Spectrometry -- Methods
KW  - Physical Examination
KW  - Chronic Disease
KW  - Endoscopy, Digestive System -- Methods
KW  - Male
KW  - Treatment Outcomes
KW  - Diagnosis, Differential
KW  - Chromatography, Liquid -- Methods
KW  - Celiac Disease -- Diagnosis
KW  - Intestines -- Pathology
SP  - e23
EP  - e28
JO  - Mayo Clinic Proceedings
JF  - Mayo Clinic Proceedings
JA  - MAYO CLIN PROC
VL  - 91
IS  - 2
CY  - Philadelphia, Pennsylvania
PB  - Elsevier Inc.
SN  - 0025-6196
AD  - Resident in Internal Medicine, Mayo School of Graduate Medical Education, Rochester, MN
AD  - Advisor to residents and Consultant in Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN
U2  - PMID: 26769182.
DO  - 10.1016/j.mayocp.2015.07.033
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=115878394&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105212351
T1  - A case report of atrial fibrillation potentially induced by hydroxycut: a multicomponent dietary weight loss supplement devoid of sympathomimetic amines.
AU  - Karth A
AU  - Holoshitz N
AU  - Kavinsky CJ
AU  - Trohman R
AU  - McBride BF
Y1  - 2010/06//
N1  - Accession Number: 105212351. Language: English. Entry Date: 20100716. Revision Date: 20150711. Publication Type: Journal Article; algorithm; case study; tables/charts; tracings. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 8900945. 
KW  - Atrial Fibrillation -- Chemically Induced
KW  - Atrial Fibrillation -- Etiology
KW  - Dietary Supplements -- Adverse Effects
KW  - Plant Extracts -- Adverse Effects
KW  - Weight Loss
KW  - Atrial Fibrillation -- Diagnosis
KW  - Atrial Fibrillation -- Symptoms
KW  - Female
KW  - Medicine, Herbal -- Adverse Effects
KW  - Middle Age
SP  - 245
EP  - 249
JO  - Journal of Pharmacy Practice
JF  - Journal of Pharmacy Practice
JA  - J PHARM PRACT
VL  - 23
IS  - 3
CY  - Thousand Oaks, California
PB  - Sage Publications Inc.
SN  - 0897-1900
AD  - Department of Medicine, Rush University Medical Center, Chicago, IL
U2  - PMID: 21507821.
DO  - 10.1177/0897190010362104
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105212351&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 113053591
T1  - A Clinical Network Project Improves Care of Patients with Atrial Fibrillation with Rapid Ventricular Response in Victorian Emergency Departments.
AU  - Kelly, Anne-Maree
AU  - Pannifex, Jan
Y1  - 2016/03//
N1  - Accession Number: 113053591. Corporate Author: Emergency Care Clinical Network, Innovation Hub, Health Service Improvement. Language: English. Entry Date: In Process. Revision Date: 20160622. Publication Type: journal article. Journal Subset: Biomedical; Continental Europe; Europe. NLM UID: 100963739. 
SP  - e33
EP  - e36
JO  - Heart, Lung & Circulation
JF  - Heart, Lung & Circulation
JA  - HEART LUNG CIRC
VL  - 25
IS  - 3
CY  - New York, New York
PB  - Elsevier Science
AB  - Objectives: Atrial fibrillation with rapid ventricular response is a common condition in emergency departments (ED) and despite published guidelines, variation in practice is common. The aim of this nine-month evidence-based care improvement project was improving the management of atrial fibrillation with rapid ventricular response (AFRVR).Methods: This was a quality improvement project, evaluated using before and after chart review methodology. The outcomes of interest were the proportion of patients managed according to a local treatment pathway, the proportion with duration of symptoms documented, the proportion with rate control versus rhythm control strategy documented and the proportion with a CHADS2 score (or equivalent) documented.Results: Ten ED participated. Management according to a local treatment pathway increased from 8% (27/326) of patients to 68% (191/281); p<0.0001. The proportion of patients with symptom duration documented increased from 62% (201/326) to 81% (227/281); p<0.0001. The proportion of patients with CHADS2 score (similar) documented increased from 16% (49/310) to 47% (126/268); p<0.0001.Conclusion: This project has led to clinically and statistically significant improvements in management of AFRVR across a health system, although there is still room for improvement. Work continues to embed these gains and make further improvements.
SN  - 1443-9506
AD  - Department of Health and Human Services, Melbourne, Vic, Australia
U2  - PMID: 26691143.
DO  - 10.1016/j.hlc.2015.07.009
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 116221264
T1  - A Comparison of Heartrate and Rating of Perceived Exertion-based Methods for Prescribing Exercise Intensity in Individuals with Permanent Atrial Fibrillation.
AU  - Carrick-Ranson, Graeme
AU  - Reading, Stacey
AU  - Morrison, Cindy
Y1  - 2016/06/02/2016Supplement 1
N1  - Accession Number: 116221264. Language: English. Entry Date: In Process. Revision Date: 20160709. Publication Type: Article. Supplement Title: 2016Supplement 1. Journal Subset: Biomedical; Continental Europe; Europe. NLM UID: 100963739. 
SP  - S38
EP  - S38
JO  - Heart, Lung & Circulation
JF  - Heart, Lung & Circulation
JA  - HEART LUNG CIRC
VL  - 25
CY  - New York, New York
PB  - Elsevier Science
SN  - 1443-9506
AD  - The University Of Auckland, Auckland, New Zealand
DO  - 10.1016/j.hlc.2016.05.099
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=116221264&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105145572
T1  - A comparison of stresses in implantation for grafted and plate-and-screw mandible reconstruction.
AU  - Nagasao T
AU  - Miyamoto J
AU  - Tamaki T
AU  - Kawana H
Y1  - 2010/03//
N1  - Accession Number: 105145572. Language: English. Entry Date: 20100723. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Dental Care; Perioperative Care. NLM UID: 101576782. 
KW  - Orthopedic Fixation Devices
KW  - Bone Transplantation -- Equipment and Supplies
KW  - Dentistry
KW  - Mandible -- Surgery
KW  - Maxillofacial Prosthesis
KW  - Surgery, Reconstructive -- Equipment and Supplies
KW  - Biomechanics
KW  - Bone Transplantation -- Methods
KW  - Computer Simulation
KW  - Dental Implants
KW  - Dental Models
KW  - Finite Element Analysis
KW  - Human
KW  - Prosthesis Design
KW  - Surgery, Reconstructive -- Methods
KW  - Stress, Mechanical
SP  - 346
EP  - 356
JO  - Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology
JF  - Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology
JA  - ORAL SURG ORAL MED ORAL PATHOL ORAL RADIOL ENDO
VL  - 109
IS  - 3
CY  - New York, New York
PB  - Elsevier Science
AB  - OBJECTIVE: During oral rehabilitation by dental implantation for mandibles reconstructed with plate and screws, intensified stresses can develop at the implant-bone interfaces and fixation screw-bone interfaces that might cause complications at these interfaces. The present study aims to evaluate the stresses occurring at these sites using the finite element method. STUDY DESIGN: Ten computer-aided design models simulating 10 mandibles were produced and were termed normal models. Simulation surgery was performed on these normal models, where parts of the models were removed and replaced by fibula or reconstruction plates plus screws. Depending on the replaced part (body [B] or body and symphysis [BS]) and the reconstruction materials (fibula [Fib] or reconstruction plate [Plate]), the modified models were termed B-Fib, B-Plate, BS-Fib, and BS-Plate models, respectively. For each model, an implant was embedded in the first molar region. Stresses occurring at the implant-bone interfaces and fixation screw-bone interfaces on mastication were calculated using the finite element method and compared among the model groups. RESULTS: The stresses at the implant-bone interfaces showed no statistically significant differences among the 5 model groups. With the B-Plate and BS-Plate models, stresses at the fixation screw-bone interfaces were nearly twice as intense as those at the implant-bone interfaces. CONCLUSION: If it is allowed that complication risks correlate with stresses, fixation screws are more subject to failure than implants in performing implantation for mandibles reconstructed with a plate and fixation screws. Therefore, the fixation screws deserve special attention in performing oral rehabilitation for such patients.
SN  - 1079-2104
AD  - Department of Reconstructive Surgery, Keio University Hospital, Tokyo, Japan. nagasao@sc.itc.keio.ac.jp
U2  - PMID: 20097102.
DO  - 10.1016/j.tripleo.2009.10.009
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109831377
T1  - A Novel Microwave Catheter Can Perform Noncontact Circumferential Endocardial Ablation in a Model of Pulmonary Vein Isolation.
AU  - Qian, Pierre
AU  - Barry, Michael Anthony
AU  - Nguyen, Trang
AU  - Ross, David
AU  - Kovoor, Pramesh
AU  - Mcewan, Alistair
AU  - Thomas, Stuart
AU  - Thiagalingam, Aravinda
Y1  - 2015/07//
N1  - Accession Number: 109831377. Language: English. Entry Date: 20150717. Revision Date: 20160630. Publication Type: Journal Article; diagnostic images; pictorial; research; tables/charts. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9010756. 
KW  - Atrial Fibrillation -- Surgery
KW  - Pulmonary Veins -- Surgery
KW  - Catheter Ablation -- Methods
KW  - Catheter Ablation -- Equipment and Supplies
KW  - Microwaves -- Utilization
KW  - Models, Anatomic
KW  - Descriptive Statistics
KW  - Data Analysis Software
KW  - Confidence Intervals
KW  - Unpaired T-Tests
KW  - Animal Studies
KW  - Cattle
KW  - In Vitro Studies
SP  - 799
EP  - 804
JO  - Journal of Cardiovascular Electrophysiology
JF  - Journal of Cardiovascular Electrophysiology
JA  - J CARDIOVASC ELECTROPHYSIOL
VL  - 26
IS  - 7
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Noncontact Circumferential Microwave Catheter Ablation Introduction Pulmonary vein isolation is an effective treatment for atrial fibrillation. Current endocardial ablation techniques require catheter contact for lesion formation. Inadequate or inconsistent catheter contact results in difficulty with achieving acute and long-term isolation and consequent atrial arrhythmia recurrence. Microwave energy produces radiant heating and therefore can be used for noncontact catheter ablation. We hypothesized that it is possible to design a microwave catheter to produce a circumferential transmural thermal lesion in an in vitro model of a pulmonary vein antrum. Methods and Results A monopole microwave catheter with a sideways firing axially symmetrical heating pattern was designed. Noncontact ablations were performed in a perfused pulmonary vein model constructed from microwave myocardial phantom embedded with a sheet of thermochromic liquid crystal to permit visualization and measurement of thermal lesions from color changes. 1200 J ablations were performed at 150 W for 80 seconds and 120 W for 100 seconds at high (0.8 L/min) and low (0.06 L/min) flow through the modeled pulmonary vein. Myocardial tissue was substituted for the phantom material and ablations repeated at 150 W for 180 seconds and stained with nitro-blue tetrazolium. The catheter was able to induce deep circumferential antral lesions in myocardial phantom and myocardial tissue. Higher power and shorter ablations delivering the same amount of microwave energy resulted in larger lesions with less surface sparing. Conclusions A microwave catheter can be designed to produce a circumferential thermal lesion on noncontact ablation and may have possible applications for pulmonary vein isolation.
SN  - 1045-3873
AD  - Cardiology Department, Westmead Hospital
AD  - Cardiology Department, Westmead Hospital; School of Electrical and Information Engineering, University of Sydney
AD  - Cardiology Department, Westmead Hospital; Sydney Medical School University of Sydney
U2  - PMID: 25871772.
DO  - 10.1111/jce.12683
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109831377&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109761415
T1  - A U-shaped association between consumption of marine n-3 fatty acids and development of atrial fibrillation/atrial flutter-a Danish cohort study.
AU  - Rix, Thomas A
AU  - Joensen, Albert M
AU  - Riahi, Sam
AU  - Lundbye-Christensen, Søren
AU  - Tjønneland, Anne
AU  - Schmidt, Erik B
AU  - Overvad, Kim
Y1  - 2014/11//
N1  - Accession Number: 109761415. Language: English. Entry Date: 20150605. Revision Date: 20151102. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Instrumentation: Food Frequency Questionnaire (FFQ). NLM UID: 100883649. 
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Atrial Flutter -- Prevention and Control
KW  - Diet
KW  - Fatty Acids, Omega-3 -- Administration and Dosage
KW  - Fish
KW  - Seafood
KW  - Animals
KW  - Atrial Fibrillation -- Diagnosis
KW  - Atrial Fibrillation -- Epidemiology
KW  - Atrial Flutter -- Diagnosis
KW  - Atrial Flutter -- Epidemiology
KW  - Behavior
KW  - Chaos Theory
KW  - Clinical Assessment Tools
KW  - Cox Proportional Hazards Model
KW  - Data Collection
KW  - Denmark
KW  - Docosahexaenoic Acids -- Administration and Dosage
KW  - Eicosapentaenoic Acid -- Administration and Dosage
KW  - Fatty Acids, Unsaturated -- Administration and Dosage
KW  - Female
KW  - Human
KW  - Incidence
KW  - Male
KW  - Middle Age
KW  - Multivariate Analysis
KW  - Probability
KW  - Questionnaires
KW  - Risk Assessment
KW  - Risk Factors
SP  - 1554
EP  - 1561
JO  - EP: Europace
JF  - EP: Europace
JA  - EUROPACE
VL  - 16
IS  - 11
PB  - Oxford University Press / USA
SN  - 1099-5129
AD  - Department of Cardiology, Aalborg AF Study Group, Center for Cardiovascular Research, Aalborg University Hospital, 9100 Aalborg, Denmark Section for Epidemiology, Department of Public Health, Aarhus University, 8000 Aarhus, Denmark tar@rn.dk.
AD  - Department of Cardiology, Aalborg AF Study Group, Center for Cardiovascular Research, Aalborg University Hospital, 9100 Aalborg, Denmark.
AD  - Department of Cardiology, Aalborg AF Study Group, Center for Cardiovascular Research, Aalborg University Hospital, 9100 Aalborg, Denmark Department of Health Science and Technology, Faculty of Medicine, Aalborg University, 9220 Aalborg, Denmark.
AD  - Danish Cancer Society Research Center, 2100 Copenhagen, Denmark.
AD  - Department of Cardiology, Aalborg AF Study Group, Center for Cardiovascular Research, Aalborg University Hospital, 9100 Aalborg, Denmark Section for Epidemiology, Department of Public Health, Aarhus University, 8000 Aarhus, Denmark.
U2  - PMID: 24574493.
DO  - europace/euu019
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 113467325
T1  - Action to Support Practices Implement Research Evidence (ASPIRE): protocol for a cluster-randomised evaluation of adaptable implementation packages targeting 'high impact' clinical practice recommendations in general practice.
AU  - Willis, Thomas A.
AU  - Hartley, Suzanne
AU  - Glidewell, Liz
AU  - Farrin, Amanda J.
AU  - Lawton, Rebecca
AU  - McEachan, Rosemary R. C.
AU  - Ingleson, Emma
AU  - Heudtlass, Peter
AU  - Collinson, Michelle
AU  - Clamp, Susan
AU  - Hunter, Cheryl
AU  - Ward, Vicky
AU  - Hulme, Claire
AU  - Meads, David
AU  - Bregantini, Daniele
AU  - Carder, Paul
AU  - Foy, Robbie
Y1  - 2016/02/29/
N1  - Accession Number: 113467325. Corporate Author: ASPIRE programme. Language: English. Entry Date: In Process. Revision Date: 20160507. Publication Type: journal article. Journal Subset: Biomedical; Europe; Health Services Administration; UK & Ireland. NLM UID: 101258411. 
SP  - 1
EP  - 11
JO  - Implementation Science
JF  - Implementation Science
JA  - IMPLEMENT SCI
VL  - 11
PB  - BioMed Central
AB  - Background: There are recognised gaps between evidence and practice in general practice, a setting which provides particular challenges for implementation. We earlier screened clinical guideline recommendations to derive a set of 'high impact' indicators based upon criteria including potential for significant patient benefit, scope for improved practice and amenability to measurement using routinely collected data. We aim to evaluate the effectiveness and cost-effectiveness of a multifaceted, adaptable intervention package to implement four targeted, high impact recommendations in general practice.Methods/design: The research programme Action to Support Practice Implement Research Evidence (ASPIRE) includes a pair of pragmatic cluster-randomised trials which use a balanced incomplete block design. Clusters are general practices in West Yorkshire, United Kingdom (UK), recruited using an 'opt-out' recruitment process. The intervention package adapted to each recommendation includes combinations of audit and feedback, educational outreach visits and computerised prompts with embedded behaviour change techniques selected on the basis of identified needs and barriers to change. In trial 1, practices are randomised to adapted interventions targeting either diabetes control or risky prescribing and those in trial 2 to adapted interventions targeting either blood pressure control in patients at risk of cardiovascular events or anticoagulation in atrial fibrillation. The respective primary endpoints comprise achievement of all recommended target levels of haemoglobin A1c (HbA1c), blood pressure and cholesterol in patients with type 2 diabetes, a composite indicator of risky prescribing, achievement of recommended blood pressure targets for specific patient groups and anticoagulation prescribing in patients with atrial fibrillation. We are also randomising practices to a fifth, non-intervention control group to further assess Hawthorne effects. Outcomes will be assessed using routinely collected data extracted 1 year after randomisation. Economic modelling will estimate intervention cost-effectiveness. A process evaluation involving eight non-trial practices will examine intervention delivery, mechanisms of action and unintended consequences.Discussion: ASPIRE will provide 'real-world' evidence about the effects, cost-effectiveness and delivery of adapted intervention packages targeting high impact recommendations. By implementing our adaptable intervention package across four distinct clinical topics, and using 'opt-out' recruitment, our findings will provide evidence of wider generalisability.Trial Registration: ISRCTN91989345.
SN  - 1748-5908
AD  - Leeds Institute of Health Sciences, University of Leeds, Leeds LS2 9JT, UK
AD  - Leeds Institute of Clinical Trials Research, University of Leeds, Leeds LS2 9JT, UK
AD  - School of Psychology, University of Leeds, Leeds LS2 9LZ, UK
AD  - Bradford Institute for Health Research, Bradford Royal Infirmary, Bradford BD9 6RJ, UK
AD  - West Yorkshire Research Service, Bradford Districts Clinical Commissioning Group, Douglas Mill, Bradford BD5 7JR, UK.
U2  - PMID: 26923369.
DO  - 10.1186/s13012-016-0387-5
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=113467325&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109050876
T1  - Acupuncture Antiarrhythmic Effects on Drug Refractory Persistent Atrial Fibrillation: Study Protocol for a Randomized, Controlled Trial.
AU  - Park, Jimin
AU  - Kim, Hyun Soo
AU  - Lee, Seung Min
AU  - Yoon, Kanghyun
AU  - Kim, Woo-shik
AU  - Woo, Jong Shin
AU  - Lee, Sanghoon
AU  - Kim, Jin-Bae
AU  - Kim, Weon
Y1  - 2015/02/17/
N1  - Accession Number: 109050876. Language: English. Entry Date: In Process. Revision Date: 20151015. Publication Type: Article. Journal Subset: Alternative/Complementary Therapies; Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 101215021. 
SP  - 1
EP  - 6
JO  - Evidence-based Complementary & Alternative Medicine (eCAM)
JF  - Evidence-based Complementary & Alternative Medicine (eCAM)
JA  - EVID BASED COMPLEMENT ALTERN MED
VL  - 2015
CY  - New York, New York
PB  - Hindawi Publishing Corporation
AB  - Background. Atrial fibrillation (AF) is the most common form of arrhythmia. Several trials have suggested that acupuncture may prevent AF. However, the efficacy of acupuncture for AF prevention has not been well investigated. Therefore, we designed a prospective, two-parallel-armed, participant and assessor blinded, randomized, sham-controlled clinical trial to investigate acupuncture in persistent AF (ACU-AF). Methods. A total of 80 participants will be randomly assigned to active acupuncture or sham acupuncture groups in a 1 : 1 ratio. Both groups will take the same antiarrhythmic medication during the study period. Patients will receive 10 sessions of acupuncture treatment once a week for 10 weeks. The primary endpoint is AF recurrence rate. Secondary endpoints are left atrium (LA) and left atrial appendage (LAA) changes in function and volume, and inflammatory biomarker changes. Ethics. This study protocol was approved by the institutional review boards (IRBs) of Kyung Hee University Hospital (number 1335-04). This trial is registered with clinicaltrials.gov <ext-link>NCT02110537</ext-link>.
SN  - 1741-427X
AD  - Department of Acupuncture and Moxibustion, College of Korean Medicine, Kyung Hee University, Seoul 130-701, Republic of Korea
AD  - Division of Cardiology, Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul 130-701, Republic of Korea
DO  - 10.1155/2015/613970
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109050876&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108824781
T1  - Acupuncture Antiarrhythmic Effects on Drug Refractory Persistent Atrial Fibrillation: Study Protocol for a Randomized, Controlled Trial.
AU  - Jimin Park
AU  - Hyun Soo Kim
AU  - Seung Min Lee
AU  - Kanghyun Yoon
AU  - Woo-shik Kim
AU  - Jong Shin Woo
AU  - Sanghoon Lee
AU  - Jin-Bae Kim
AU  - Weon Kim
Y1  - 2015/01//
N1  - Accession Number: 108824781. Language: English. Entry Date: In Process. Revision Date: 20150825. Publication Type: journal article; pictorial; research; tables/charts; randomized controlled trial. Journal Subset: Alternative/Complementary Therapies; Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice. Grant Information: This study is supported by grants from the Korean Government(Ministry of Health) (no. HI13C0580).. NLM UID: 101215021. 
KW  - Acupuncture -- Methods
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Human
KW  - Randomized Controlled Trials
KW  - Prospective Studies
KW  - Random Assignment
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Antiarrhythmia Agents -- Therapeutic Use
KW  - Echocardiography, Transesophageal
KW  - Multicenter Studies
KW  - South Korea
KW  - Risk Assessment
KW  - Electrocardiography
KW  - Sample Size
KW  - Descriptive Statistics
KW  - T-Tests
KW  - Mann-Whitney U Test
KW  - Chi Square Test
KW  - Fisher's Exact Test
KW  - Kaplan-Meier Estimator
KW  - Cox Proportional Hazards Model
KW  - Regression
KW  - Data Analysis Software
KW  - Clinical Assessment Tools
KW  - Funding Source
SP  - 1
EP  - 6
JO  - Evidence-based Complementary & Alternative Medicine (eCAM)
JF  - Evidence-based Complementary & Alternative Medicine (eCAM)
JA  - EVID BASED COMPLEMENT ALTERN MED
CY  - New York, New York
PB  - Hindawi Publishing Corporation
AB  - Background. Atrial fibrillation (AF) is the most common form of arrhythmia. Several trials have suggested that acupuncture may prevent AF. However, the efficacy of acupuncture for AF prevention has not been well investigated. Therefore, we designed a prospective, two-parallel-armed, participant and assessor blinded, randomized, sham-controlled clinical trial to investigate acupuncture in persistent AF (ACU-AF). Methods. A total of 80 participants will be randomly assigned to active acupuncture or sham acupuncture groups in a 1 : 1 ratio. Both groups will take the same antiarrhythmic medication during the study period. Patients will receive 10 sessions of acupuncture treatment once a week for 10 weeks. The primary endpoint is AF recurrence rate. Secondary endpoints are left atrium (LA) and left atrial appendage (LAA) changes in function and volume, and inflammatory biomarker changes. Ethics. This study protocol was approved by the institutional review boards (IRBs) of Kyung Hee University Hospital (number 1335-04). This trial is registered with clinicaltrials.gov NCT02110537.
SN  - 1741-427X
AD  - Department of Acupuncture and Moxibustion, College of Korean Medicine, Kyung Hee University, Seoul 130-701, Republic of Korea
AD  - Division of Cardiology, Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul 130-701, Republic of Korea
DO  - 10.1155/2015/613970
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108824781&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 112972666
T1  - Acute heart failure admissions in New South Wales and the Australian Capital Territory: the NSW HF Snapshot Study.
AU  - Newton, Phillip J.
AU  - Davidson, Patricia M.
AU  - Reid, Christopher M.
AU  - Krum, Henry
AU  - Hayward, Christopher
AU  - Sibbritt, David W.
AU  - Banks, Emily
AU  - MacDonald, Peter S.
Y1  - 2016/02/15/
N1  - Accession Number: 112972666. Language: English. Entry Date: 20160701. Revision Date: 20160701. Publication Type: journal article. Journal Subset: Australia & New Zealand; Biomedical; Double Blind Peer Reviewed; Peer Reviewed. Instrumentation: Charlson Comorbidity Index (CCI). NLM UID: 0400714. 
KW  - Diuretics -- Administration and Dosage
KW  - Heart Failure -- Therapy
KW  - Hyperbaric Oxygenation -- Methods
KW  - Continuous Positive Airway Pressure -- Methods
KW  - Female
KW  - Audit
KW  - New South Wales
KW  - Risk Factors
KW  - Treatment Outcomes
KW  - Atrial Fibrillation
KW  - Aged
KW  - Comorbidity
KW  - Cross Sectional Studies
KW  - Medication Compliance
KW  - Administration, Intravenous
KW  - Human
KW  - Male
KW  - Prospective Studies
KW  - Australian Capital Territory
KW  - Acute Disease
KW  - Middle Age
KW  - Heart Failure -- Mortality
KW  - Aged, 80 and Over
KW  - Frail Elderly
KW  - Validation Studies
KW  - Comparative Studies
KW  - Evaluation Research
KW  - Multicenter Studies
SP  - 113.e1
EP  - 113.e8
JO  - Medical Journal of Australia
JF  - Medical Journal of Australia
JA  - MED J AUST
VL  - 204
IS  - 3
PB  - Australasian Medical Publishing Company
AB  - Objective: The primary aim of the NSW Heart Failure (HF) Snapshot was to obtain a representative cross-sectional view of patients with acute HF and their management in New South Wales and Australian Capital Territory hospitals.Design and Setting: A prospective audit of consecutive patients admitted to 24 participating hospitals in NSW and the ACT with a diagnosis of acute HF was conducted from 8 July 2013 to 8 August 2013.Results: A total of 811 participants were recruited (mean age, 77 ± 13 years; 58% were men; 42% had a left ventricular ejection fraction ≥ 50%). The median Charlson Comorbidity Index score was 3, with ischaemic heart disease (56%), renal disease (55%), diabetes (38%) and chronic lung disease (32%) the most frequent comorbidities; 71% of patients were assessed as frail. Intercurrent infection (22%), non-adherence to prescribed medication (5%) or to dietary or fluid restrictions (16%), and atrial fibrillation/flutter (15%) were the most commonly identified precipitants of HF. Initial treatment included intravenous diuretics (81%), oxygen therapy (87%), and bimodal positive airways pressure or continuous positive airways pressure ventilation (17%). During the index admission, 6% of patients died. The median length of stay in hospital was 6 days, but ranged between 3 and 12 days at different hospitals. Just over half the patients (59%) were referred to a multidisciplinary HF service. Discharge medications included angiotensin-converting enzyme inhibitors/angiotensin receptor blockers (59%), β-blockers (66%) and loop diuretics (88%).Conclusions: Patients admitted to hospital with acute HF in NSW and the ACT were generally elderly and frail, with multiple comorbidities. Evidence-based therapies were underused, and there was substantial interhospital variation in the length of stay. We anticipate that the results of the HF Snapshot will inform the development of strategies for improving the uptake of evidence-based therapies, and hence outcomes, for HF patients.
SN  - 0025-729X
AD  - Centre for Cardiovascular and Chronic Care, University of Technology Sydney, Sydney, NSW
AD  - Johns Hopkins University, Baltimore, Md, USA
AD  - Curtin University, Perth, WA
AD  - Monash Centre of Cardiovascular Research and Education in Therapeutics, Monash University, Melbourne, VIC
AD  - St Vincent's Hospital, Sydney, NSW
AD  - Australian Research Centre in Complementary and Integrative Medicine, University of Technology Sydney, Sydney, NSW
AD  - National Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT
U2  - PMID: 26866550.
DO  - 10.5694/mja15.00801
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=112972666&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108114370
T1  - Added Predictive Ability of the CHA2DS2VASc Risk Score for Stroke and Death in Patients With Atrial Fibrillation: The Prospective Danish Diet, Cancer, and Health Cohort Study.
AU  - Larsen TB
AU  - Lip GY
AU  - Skjøth F
AU  - Due KM
AU  - Overvad K
AU  - Hvilsted Rasmussen L
Y1  - 2012/05//
N1  - Accession Number: 108114370. Language: English. Entry Date: 20120928. Revision Date: 20150712. Publication Type: Journal Article; research. Journal Subset: Biomedical; USA. NLM UID: 101489148. 
KW  - Atrial Fibrillation -- Epidemiology
KW  - Stroke -- Epidemiology
KW  - Administration, Oral
KW  - Aged
KW  - Anticoagulants -- Administration and Dosage
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Atrial Fibrillation -- Mortality
KW  - Denmark
KW  - Diet -- Adverse Effects
KW  - Female
KW  - Human
KW  - Incidence
KW  - Life Style
KW  - Male
KW  - Middle Age
KW  - Neoplasms -- Epidemiology
KW  - Predictive Value of Tests
KW  - Prognosis
KW  - Prospective Studies
KW  - ROC Curve
KW  - Data Collection
KW  - Risk Assessment
KW  - Risk Factors
KW  - Stroke -- Mortality
KW  - Stroke -- Prevention and Control
KW  - Time Factors
SP  - 335
EP  - 342
JO  - Circulation: Cardiovascular Quality & Outcomes
JF  - Circulation: Cardiovascular Quality & Outcomes
JA  - CIRC CARDIOVASC QUAL OUTCOMES
VL  - 5
IS  - 3
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
SN  - 1941-7713
AD  - Department of Cardiology, Aalborg AF Study Group, Cardiovascular Research Centre, Aarhus University Hospital, Aalborg, Denmark.
U2  - PMID: 22534406.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108114370&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104312627
T1  - Adherence to Mediterranean diet and intake of antioxidants influence spontaneous conversion of atrial fibrillation.
AU  - Mattioli AV
AU  - Miloro C
AU  - Pennella S
AU  - Pedrazzi P
AU  - Farinetti A
Y1  - 2013/02//
N1  - Accession Number: 104312627. Language: English. Entry Date: 20130823. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. Special Interest: Nutrition. NLM UID: 9111474. 
KW  - Antioxidants -- Administration and Dosage
KW  - Atrial Fibrillation -- Diet Therapy
KW  - Mediterranean Diet
KW  - Patient Compliance
KW  - Adult
KW  - Aged
KW  - Atrial Fibrillation -- Physiopathology
KW  - Body Mass Index
KW  - Case Control Studies
KW  - Female
KW  - Human
KW  - Life Style
KW  - Male
KW  - Middle Age
KW  - Nutritional Assessment
KW  - Nutritional Status
KW  - Questionnaires
SP  - 115
EP  - 121
JO  - Nutrition, Metabolism & Cardiovascular Diseases
JF  - Nutrition, Metabolism & Cardiovascular Diseases
JA  - NUTR METAB CARDIOVASC DIS
VL  - 23
IS  - 2
CY  - New York, New York
PB  - Elsevier Science
SN  - 0939-4753
AD  - Department of Biomedical Science, Sect of Cardiology, University of Modena and Reggio Emilia, Modena, Italy. Electronic address: annavittoria.mattioli@unimore.it.
U2  - PMID: 21798731.
DO  - 10.1016/j.numecd.2011.03.005
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104312627&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107845946
T1  - Adjusting Warfarin Doses.
AU  - Dietrich, Eric
AU  - Kuritzky, Louis
Y1  - 2014/04//
N1  - Accession Number: 107845946. Language: English. Entry Date: 20140509. Revision Date: 20150712. Publication Type: Journal Article; case study; tables/charts. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Gerontologic Care. NLM UID: 750110. 
KW  - Warfarin -- Administration and Dosage
KW  - Atrial Fibrillation -- Complications
KW  - Stroke -- Prevention and Control
KW  - Aged, 80 and Over
KW  - Female
KW  - International Normalized Ratio
KW  - Diet
KW  - Medication Compliance
KW  - Vitamin K
SP  - 281
EP  - 284
JO  - Consultant (00107069)
JF  - Consultant (00107069)
JA  - CONSULTANT
VL  - 54
IS  - 4
CY  - Framingham, Massachusetts
PB  - United Business Media
SN  - 0010-7069
AD  - UF Colleges of Pharmacy and Medicine.
AD  - Family physician, University of Florida Family Medicine Residency Program
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107845946&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - THES
ID  - 109853753
T1  - Advanced heart failure in older women with heart failure and preserved systolic function.
AU  - Huiskes, Bonita Louise
Y1  - 2009/01//
N1  - Accession Number: 109853753. Language: English. Entry Date: 20110513. Revision Date: 20150923. Publication Type: Doctoral Dissertation; research. 
KW  - Heart Failure -- In Old Age
KW  - Palliative Care
KW  - Quality of Life
KW  - Aged
KW  - Cross Sectional Studies
KW  - Female
KW  - Human
KW  - Morbidity
KW  - Mortality
KW  - New York
KW  - Women
SP  - 284 p
EP  - 284 p
JO  - Advanced Heart Failure in Older Women With Heart Failure & Preserved Systolic Function
JF  - Advanced Heart Failure in Older Women With Heart Failure & Preserved Systolic Function
PB  - University of California, San Francisco
AB  - Heart failure with preserved systolic function (HFPSF) accounts for approximately half of all heart failure (HF) patients, a majority of whom are older women. Little is known about this HF subgroup since they have not been included in most HF clinical trials and other research studies. Moreover, the characteristics of those who have advanced disease have not been well described.The primary aims of this dissertation were (1) to use a cross-sectional design to describe the characteristics of older women with advanced HFPSF and (2) to examine potential factors influencing their quality of life (QOL).The variables included were demographic, clinical, symptom, comfort, and functional capacity.Sixty women (76 +/- 7.7 years; 86.7% Caucasian) with New York Heart Association Class III HFPSF were recruited from two outpatient HF clinics. The women had high symptom prevalence (13.2 +/- 6.4) and burden (2.1 +/- 0.43 on a 0-4 scale), impaired functional capacity (mean 6-minute walk distance: 201.4 +/- 117.1 meters) and multiple co-morbidities (4.65 +/- 1.55). Co-morbid medical conditions associated with increased mortality and morbidity risk in HFPSF included pulmonary hypertension (76%), compromised renal function (73%), atrial fibrillation (66.7%), coronary artery disease (45%), and diabetes (40%).Using a multiple linear regression model to control for disease severity, clinical status, and functional capacity, age (p = .023), comfort (p = .002) and symptom burden (p = .001) were significantly associated with QOL. The final overall model explained 66% of the variance in QOL (p < .001). Age explained 4% of the variance (p = 0.023), total symptom burden explained 14% of the variance (p = < .001), and comfort explained 7% of the variance (p = 0.002) in QOL.Interventions reducing symptom burden and enhancing comfort for older women with advanced HFPSF may result in improved QOL. Addressing factors germane to QOL is congruent with palliative care in advanced chronic illness, since QOL enhancement is a palliative care goal.The unrecognized palliative need of advanced HFPSF patients, a group comprised largely of older women, must be addressed. This segment of our aging society deserves better quality in the last phase of their life journey.
SN  - 9781109578478
AV  - UMI Order AAI3390049
M1  - Ph.D.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109853753&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106594649
T1  - Advisor forum. Natural cardioversion?
AU  - Cohen J
AU  - Keller NM
Y1  - 2005/01//2005 Jan
N1  - Accession Number: 106594649. Language: English. Entry Date: 20050318. Revision Date: 20150711. Publication Type: Journal Article; brief item; questions and answers. Journal Subset: Nursing; USA. NLM UID: 9804511. 
KW  - Atrial Fibrillation -- Therapy
KW  - Cardioversion
KW  - Running
SP  - 50
EP  - 54
JO  - Clinical Advisor
JF  - Clinical Advisor
JA  - CLIN ADVIS
VL  - 8
IS  - 1
CY  - New York, New York
PB  - Haymarket Media, Inc.
SN  - 1524-7317
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106594649&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103857512
T1  - Aggressive Risk Factor Reduction Study for Atrial Fibrillation and Implications for the Outcome of Ablation: The ARREST-AF Cohort Study.
AU  - Pathak, Rajeev K
AU  - Middeldorp, Melissa E
AU  - Lau, Dennis H
AU  - Mehta, Abhinav B
AU  - Mahajan, Rajiv
AU  - Twomey, Darragh
AU  - Alasady, Muayad
AU  - Hanley, Lorraine
AU  - Antic, Nicholas A
AU  - McEvoy, R Doug
AU  - Kalman, Jonathan M
AU  - Abhayaratna, Walter P
AU  - Sanders, Prashanthan
Y1  - 2014/12/02/
N1  - Accession Number: 103857512. Language: English. Entry Date: 20150313. Revision Date: 20150710. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 8301365. 
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Atrial Fibrillation -- Surgery
KW  - Catheter Ablation
KW  - Alcohol Drinking
KW  - Atrial Fibrillation -- Etiology
KW  - Blood Glucose -- Analysis
KW  - Blood Pressure
KW  - Body Mass Index
KW  - Case Control Studies
KW  - Prospective Studies
KW  - Hyperlipidemia -- Blood
KW  - Hyperlipidemia -- Drug Therapy
KW  - Female
KW  - Hemoglobin A, Glycosylated -- Analysis
KW  - Human
KW  - Life Style
KW  - Lipids -- Blood
KW  - Male
KW  - Middle Age
KW  - Recurrence
KW  - Risk Factors
KW  - Severity of Illness Indices
KW  - Sleep Apnea, Obstructive -- Diagnosis
KW  - Sleep Apnea, Obstructive -- Therapy
KW  - Smoking Cessation
KW  - Weight Reduction Programs
SP  - 2222
EP  - 2231
JO  - Journal of the American College of Cardiology (JACC)
JF  - Journal of the American College of Cardiology (JACC)
JA  - J AM COLL CARDIOL
VL  - 64
IS  - 21
CY  - New York, New York
PB  - Elsevier Science
SN  - 0735-1097
AD  - Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute, University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia.
AD  - Research School of Finance, Actuarial Studies and Applied Statistics, Australian National University, Canberra, Australia.
AD  - Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute, University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; Research School of Finance, Actuarial Studies and Applied Statistics, Australian National University, Canberra, Australia.
AD  - Adelaide Institute for Sleep Health, Repatriation General Hospital and Department of Medicine, Flinders University, Adelaide, Australia.
AD  - Department of Cardiology, Royal Melbourne Hospital and the Department of Medicine, University of Melbourne, Melbourne, Australia.
AD  - College of Medicine, Biology and Environment, Australian National University and Canberra Hospital, Canberra, Australia.
AD  - Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute, University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia. Electronic address: prash.sanders@adelaide.edu.au.
U2  - PMID: 25456757.
DO  - 10.1016/j.jacc.2014.09.028
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103857512&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104189878
T1  - Alcohol intake and prognosis of atrial fibrillation.
AU  - Overvad, Thure Filskov
AU  - Rasmussen, Lars Hvilsted
AU  - Skjøth, Flemming
AU  - Overvad, Kim
AU  - Albertsen, Ida Ehlers
AU  - Lane, Deirdre A
AU  - Lip, Gregory Y H
AU  - Larsen, Torben Bjerregaard
Y1  - 2013/08//
N1  - Accession Number: 104189878. Language: English. Entry Date: 20131108. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Blind Peer Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. NLM UID: 9602087. 
KW  - Alcohol Drinking
KW  - Alcohol Drinking -- Epidemiology
KW  - Atrial Fibrillation -- Complications
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Atrial Fibrillation -- Epidemiology
KW  - Thromboembolism -- Epidemiology
KW  - Thromboembolism -- Etiology
KW  - Thromboembolism -- Prevention and Control
KW  - Age Factors
KW  - Aged
KW  - Anticoagulants -- Therapeutic Use
KW  - Prospective Studies
KW  - Comorbidity
KW  - Denmark
KW  - Female
KW  - Human
KW  - Male
KW  - Medical Records -- Statistics and Numerical Data
KW  - Middle Age
KW  - Outcome Assessment -- Statistics and Numerical Data
KW  - Risk Assessment
KW  - Risk Factors
KW  - Sex Factors
SP  - 1093
EP  - 1099
JO  - Heart
JF  - Heart
JA  - HEART
VL  - 99
IS  - 15
PB  - BMJ Publishing Group
AB  - OBJECTIVE: To assess alcohol intake as a risk factor for adverse events among patients with incident atrial fibrillation (AF). DESIGN: Prospective cohort study. SETTING: Population based cohort study and nationwide Danish registries. PATIENTS: The Danish Diet, Cancer and Health study included 57 053 participants (27 178 men and 29 875 women) aged between 50 and 64 years. The study population for this study included the 3107 participants (1999 men, 1108 women) who developed incident AF after inclusion. MAIN OUTCOME MEASURES: A composite of thromboembolism or death. RESULTS: During a median follow-up of 4.9 years 608 deaths and 211 thromboembolic events occurred. Of those who developed AF, 690 (35%) men and 233 (21%) women had a high intake of alcohol (>20 drinks/week for men and >13 drinks/week for women). After adjustment for use of oral anticoagulation and components of the CHA2DS2-VASc score, men with an intake of >27 drinks/week had a higher risk for thromboembolism or death (hazard ratio (HR) 1.33, 95% CI 1.08 to 1.63) than men with an intake of <14 drinks/week. Women with an intake of >20 drinks/week also had a higher risk (HR 1.23, 95% CI 0.78 to 1.96) than women in the low intake category. The higher risk among men was primarily driven by mortality (HR 1.51, 95% CI 1.20 to 1.89), whereas the risk found among women was driven by thromboembolism (HR 1.71, 95% CI 0.81 to 3.60). CONCLUSIONS: High alcohol intake predicts thromboembolism or death, even after adjustment for established clinical risk factors, and may help identify high risk AF patients who could be targeted for stroke and cardiovascular prevention strategies.
SN  - 1355-6037
AD  - Department of Cardiology, Cardiovascular Research Centre, Aalborg University Hospital, Aalborg, Denmark. Forskningens Hus, Søndre Skovvej 15, Aalborg DK-9100, Denmark; tobl@rn.dk.
U2  - PMID: 23766449.
DO  - 10.1136/heartjnl-2013-304036
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104189878&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103759773
T1  - Alternative medicine in atrial fibrillation treatment--Yoga, acupuncture, biofeedback and more.
AU  - Kanmanthareddy, Arun
AU  - Reddy, Madhu
AU  - Ponnaganti, Gopi
AU  - Sanjani, Hari Priya
AU  - Koripalli, Sandeep
AU  - Adabala, Nivedita
AU  - Buddam, Avanija
AU  - Janga, Pramod
AU  - Lakkireddy, Thanmay
AU  - Bommana, Sudharani
AU  - Vallakati, Ajay
AU  - Atkins, Donita
AU  - Lakkireddy, Dhanunjaya
Y1  - 2015/02//
N1  - Accession Number: 103759773. Language: English. Entry Date: 20150218. Revision Date: 20150710. Publication Type: Journal Article; review; tables/charts. Journal Subset: Asia; Biomedical; Peer Reviewed. NLM UID: 101533916. 
KW  - Alternative Therapies -- Methods
KW  - Atrial Fibrillation -- Therapy
KW  - Yoga
KW  - Acupuncture
KW  - Biofeedback
KW  - Thoracic Diseases
KW  - Serial Publications
KW  - Quality of Life
KW  - Recurrence
KW  - Atrial Fibrillation -- Complications
KW  - Fatty Acids, Omega-3 -- Administration and Dosage
KW  - Vitamins
KW  - Antioxidants -- Therapeutic Use
KW  - Plants, Medicinal -- Therapeutic Use
SP  - 185
EP  - 192
JO  - Journal of Thoracic Disease
JF  - Journal of Thoracic Disease
JA  - J THORAC DIS
VL  - 7
IS  - 2
CY  - , <Blank>
PB  - Pioneer Bioscience Publishing Company
SN  - 2072-1439
AD  - School of Medicine, Creighton University, Omaha, Nebraska, USA; VA Nebraska-Western Iowa Health Care System, Omaha, Nebraska, USA
AD  - University of Kansas Medical Center and Hospital, Kansas City, Kansas, USA
AD  - Case Western Reserve University, MetroHealth Medical Center, Cleveland, Ohio, USA
U2  - PMID: 25713735.
DO  - 10.3978/j.issn.2072-1439.2015.01.13
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103759773&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107954916
T1  - Alternatives to warfarin for stroke prevention in patients with nonvalvular atrial fibrillation: A look back at the state of the field in 2012.
AU  - Truffa, Adriano A
AU  - Lopes, Renato D
AU  - Newby, L Kristin
Y1  - 2013/03//2013 Mar
N1  - Accession Number: 107954916. Language: English. Entry Date: 20130913. Revision Date: 20150712. Publication Type: Journal Article. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 0401147. 
KW  - Anticoagulants -- Therapeutic Use
KW  - Atrial Fibrillation -- Complications
KW  - Stroke -- Prevention and Control
KW  - Heterocyclic Compounds -- Therapeutic Use
KW  - Pyridines -- Therapeutic Use
KW  - Stroke -- Etiology
KW  - Thiazoles -- Therapeutic Use
KW  - Sulfur Compounds -- Therapeutic Use
KW  - Warfarin -- Adverse Effects
KW  - Warfarin -- Therapeutic Use
KW  - Alanine
KW  - Alanine -- Therapeutic Use
SP  - 146
EP  - 157
JO  - Postgraduate Medicine
JF  - Postgraduate Medicine
JA  - POSTGRAD MED
VL  - 125
IS  - 2
CY  - Philadelphia, Pennsylvania
PB  - Taylor & Francis Ltd
AB  - Stroke is the most feared complication among patients with atrial fibrillation. Oral anticoagulation therapy with vitamin K antagonists (VKAs) has been the gold standard for stroke prevention for the past 60 years. However, VKA therapy has many downsides, including risk for bleeding, a narrow therapeutic window, and the need for frequent monitoring, as well as numerous diet and lifestyle considerations that make its use cumbersome. Thus, development of new drugs that can preserve the benefits of VKAs while eliminating the negative aspects of VKA therapy has been enthusiastically sought. This article reviews the anticoagulant agents that are clinically available or under development as alternatives to VKAs for stroke prevention in patients with nonvalvular atrial fibrillation.
SN  - 0032-5481
AD  - Duke Clinical Research Institute and the Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, NC.
U2  - PMID: 23816780.
DO  - 10.3810/pgm.2013.03.2648
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108194422
T1  - And finally.
Y1  - 2006/01/19/
N1  - Accession Number: 108194422. Language: English. Entry Date: 20120427. Revision Date: 20150712. Publication Type: Journal Article; pictorial. Journal Subset: Biomedical; Europe; UK & Ireland. NLM UID: 0410033. 
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Atrial Fibrillation -- Therapy
KW  - Bereavement
KW  - Gift Giving
KW  - Heart Transplantation -- Psychosocial Factors
KW  - Mortality
KW  - Music Therapy
KW  - Personality
KW  - Smoking Cessation
KW  - Stem Cells
KW  - Transplant Donors
SP  - 98
EP  - 99
JO  - Update
JF  - Update
JA  - UPDATE (0301-5718)
VL  - 72
IS  - 1
CY  - New York, New York
PB  - Elsevier Science
SN  - 0301-5718
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108194422&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106290535
T1  - Anticoagulation in ambulatory care: an evidence-based review of the literature.
AU  - Venkatachalam V
AU  - D'Attilio K
AU  - Lewis A
AU  - Acevedo M
Y1  - 2007/03//2007 Mar-Apr
N1  - Accession Number: 106290535. Language: English. Entry Date: 20070525. Revision Date: 20150819. Publication Type: Journal Article; case study; research; systematic review; tables/charts. Journal Subset: Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Case Management; Evidence-Based Practice. NLM UID: 101291585. 
KW  - Ambulatory Care
KW  - Case Management
KW  - Warfarin -- Administration and Dosage
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Case Managers
KW  - Drug Interactions
KW  - Drug-Food Interactions
KW  - Drug-Herb Interactions
KW  - Female
KW  - International Normalized Ratio
KW  - Male
KW  - Medline
KW  - Middle Age
KW  - Patient Education
KW  - Professional Practice, Evidence-Based
KW  - Surgery, Operative
KW  - Venous Thrombosis -- Drug Therapy
KW  - Vitamin K
KW  - Human
SP  - 106
EP  - 111
JO  - Professional Case Management
JF  - Professional Case Management
JA  - PROF CASE MANAGE
VL  - 12
IS  - 2
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - Purpose of the Manuscript: Anticoagulation is warranted for the treatment of various disorders including cardiac, vascular, and postsurgical causes. Many centers have nurse case managers to coordinate care for patients on anticoagulation. This increases the demand for specific guidelines to assist nurse case managers to ensure quality of care. This review will address guidelines for nurse case managers and providers regarding initiating anticoagulation treatment and monitoring prothrombin time and international normalized ratio. Information will also be provided regarding when the nurse case manager should notify the providers to establish target international normalized ratio. This review will also provide educational tools to serve as standards for patient teaching, including drug and food interactions.Primary Practice Setting(s): This article applies to adult ambulatory practice that includes primary care, cardiology, and vascular and surgical settings.Implications for Case Management Practice:* The complexity of managing anticoagulation in ambulatory practice warrants case management.* The nurse case manager will establish a rapport with patients to improve compliance, providing patient education about diet, dosages, and drug interactions to reduce medication errors and bleeding complications.* This review on anticoagulation management will assist nurse case managers and providers to provide better quality of care.
SN  - 1932-8087
AD  - Director of Ambulatory Education at Hartford Hospital, Hartford, CT
U2  - PMID: 17413676.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109772642
T1  - Approach to the new oral anticoagulants in family practice: part 2: addressing frequently asked questions.
AU  - Douketis, James
AU  - Bell, Alan David
AU  - Eikelboom, John
AU  - Liew, Aaron
Y1  - 2014/11//
N1  - Accession Number: 109772642. Language: English. Entry Date: 20150821. Revision Date: 20150923. Publication Type: Journal Article; research; systematic review. Journal Subset: Biomedical; Blind Peer Reviewed; Canada; Expert Peer Reviewed; Peer Reviewed. Special Interest: Evidence-Based Practice. NLM UID: 0120300. 
KW  - Alanine
KW  - Anticoagulants -- Therapeutic Use
KW  - Family Practice
KW  - Heterocyclic Compounds -- Therapeutic Use
KW  - Pyridines -- Therapeutic Use
KW  - Stroke -- Prevention and Control
KW  - Sulfur Compounds -- Therapeutic Use
KW  - Venous Thromboembolism -- Drug Therapy
KW  - Acute Disease
KW  - Administration, Oral
KW  - Alanine -- Administration and Dosage
KW  - Alanine -- Therapeutic Use
KW  - Anticoagulants -- Administration and Dosage
KW  - Atrial Fibrillation -- Complications
KW  - Hemorrhage -- Chemically Induced
KW  - Hemorrhage -- Therapy
KW  - Heterocyclic Compounds -- Administration and Dosage
KW  - Human
KW  - Preoperative Care
KW  - Professional Practice, Evidence-Based
KW  - PubMed
KW  - Pyridines -- Administration and Dosage
KW  - Stroke -- Etiology
KW  - Sulfur Compounds -- Administration and Dosage
KW  - Systematic Review
KW  - Time Factors
SP  - 997
EP  - 1001
JO  - Canadian Family Physician
JF  - Canadian Family Physician
JA  - CAN FAM PHYSICIAN
VL  - 60
IS  - 11
CY  - Mississauga, Ontario
PB  - College of Family Physicians
AB  - OBJECTIVE: To address common 'what if' questions that arise relating to the long-term clinical follow-up and management of patients receiving the new oral anticoagulants (NOACs). SOURCES OF INFORMATION: For this narrative review, we searched the PubMed database for recent (January 2008 to week 32 of 2013) clinical studies relating to NOAC use for stroke prevention in atrial fibrillation and for the treatment of acute venous thromboembolism. We used this evidence base to address prespecified questions relating to NOAC use in primary care settings. MAIN MESSAGE: Dabigatran and rivaroxaban should be taken with meals to decrease dyspepsia and increase absorption, respectively. There are no dietary restrictions with any of the NOACs, beyond moderating alcohol intake, and rivaroxaban and apixaban can be crushed if required. The use of acid suppressive therapies does not appear to affect the efficacy of the NOACs. As with warfarin, patients taking NOACs should avoid long-term use of nonsteroidal anti-inflammatory and antiplatelet drugs. For patients requiring surgery, generally NOACs should be stopped 2 to 5 days before the procedure, depending on bleeding risk, and the NOAC should usually be resumed at least 24 hours after surgery. Preoperative coagulation testing is generally unnecessary. In patients who develop bleeding, minor bleeding typically does not require laboratory testing or discontinuation of NOACs; with major bleeding, the focus should be on local measures to control the bleeding and supportive care, and coagulation testing should be performed. There are currently no antidotes to reverse NOACs. The NOACs should not be used in patients with valvular heart disease, prosthetic heart valves, cancer-associated deep vein thrombosis, or superficial thrombophlebitis. CONCLUSION: Management of 'what if' scenarios for patients taking NOACs have been proposed, but additional study is needed to address these issues, especially periprocedural management and bleeding.
SN  - 0008-350X
U2  - PMID: 25392439.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107290684
T1  - Arrhythmias in the elderly: how to handle the clinical challenges.
AU  - Hariharan RR
AU  - Guerra-Garcia H
Y1  - 1997/04//
N1  - Accession Number: 107290684. Language: English. Entry Date: 19981001. Revision Date: 20150711. Publication Type: Journal Article; tracings. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 750110. 
KW  - Arrhythmia -- In Old Age
KW  - Aging
KW  - Arrhythmia -- Classification
KW  - Arrhythmia -- Diagnosis -- In Old Age
KW  - Arrhythmia -- Drug Therapy -- In Old Age
KW  - Electrocardiography
KW  - Bradycardia
KW  - Atrial Fibrillation
KW  - Heart Block
KW  - Tachycardia
KW  - Cardiovascular Agents -- Administration and Dosage -- In Old Age
KW  - Cardiovascular Agents -- Adverse Effects -- In Old Age
KW  - Drug Interactions
KW  - Male
KW  - Female
KW  - Aged
KW  - Aged, 80 and Over
SP  - 896
EP  - 907
JO  - Consultant (00107069)
JF  - Consultant (00107069)
JA  - CONSULTANT
VL  - 37
IS  - 4
CY  - Framingham, Massachusetts
PB  - United Business Media
AB  - Although often asymptomatic, cardiac arrhythmias can be ominous in elderly persons, particularly those with concomitant disease. The diagnosis of arrhythmias in the elderly differs from that in the young; keep a high index of suspicion in patients with symptoms of cerebral ischemia, angina, mental status changes, functional changes, and heart failure. Diminished exercise capacity, depressed mentation, fatigue, and syncope may be signs of bradycardia. For atrial fibrillation, pharmacologic rate control is appropriate if the patient is symptomatic and the ventricular rate is not controlled at rest and during modest exercise, low-dose vamiodarone preserves sinus rhythm with fewer side effects than other antiarrhythmics. For those with atrial flutter, the initial goal is to slow the ventricular response with digoxin, beta-blockers, or calcium channel blockers and then attempt conversion to sinus rhythm with a type I agent, such as procainamide or quinidine. Since treatment of arrhythmia may produce a clinically significant brady-arrhythmia, monitor treatment in the hospital until cardiac rhythm is stabilized and the underlying disorder is identified.
SN  - 0010-7069
AD  - Baylor College of Medicine, Houston
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - GEN
ID  - 110537028
T1  - ASK THE DOCTOR.
AU  - BHATT, DEEPAK L.
Y1  - 2015/11//
N1  - Accession Number: 110537028. Language: English. Entry Date: 20151027. Revision Date: 20151102. Publication Type: Question & Answer. Journal Subset: Biomedical; USA. NLM UID: 9425723. 
KW  - Cardioversion
KW  - Atrial Fibrillation -- Surgery
KW  - Heart Rate
KW  - Running
SP  - 2
EP  - 2
JO  - Harvard Heart Letter
JF  - Harvard Heart Letter
JA  - HARV HEART LETT
VL  - 26
IS  - 3
CY  - Stamford, Connecticut
PB  - Harvard Health Publications
SN  - 1051-5313
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=110537028&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108166894
T1  - Association of plasma phospholipid long-chain omega-3 Fatty acids with incident atrial fibrillation in older adults: the cardiovascular health study.
AU  - Wu JH
AU  - Lemaitre RN
AU  - King IB
AU  - Song X
AU  - Sacks FM
AU  - Rimm EB
AU  - Heckbert SR
AU  - Siscovick DS
AU  - Mozaffarian D
Y1  - 2012/03/06/
N1  - Accession Number: 108166894. Language: English. Entry Date: 20120511. Revision Date: 20150712. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0147763. 
KW  - Atrial Fibrillation -- Blood
KW  - Atrial Fibrillation -- Epidemiology
KW  - Fatty Acids, Omega-3 -- Blood
KW  - Seafood
KW  - Aged
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Biological Markers -- Blood
KW  - Dietary Fats -- Administration and Dosage
KW  - Docosahexaenoic Acids -- Blood
KW  - Eicosapentaenoic Acid -- Blood
KW  - Female
KW  - Prospective Studies
KW  - Human
KW  - Incidence
KW  - Male
KW  - Cox Proportional Hazards Model
KW  - Risk Factors
SP  - 1084
EP  - 1093
JO  - Circulation
JF  - Circulation
JA  - CIRCULATION
VL  - 125
IS  - 9
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - BACKGROUND: Experimental studies suggest that long-chain n-3 polyunsaturated fatty acids (n-3 PUFAs) may reduce the risk of atrial fibrillation (AF). Prior studies evaluating fish or n-3 PUFA consumption from dietary questionnaires and incident AF have been conflicting. Circulating levels of n-3 PUFAs provide an objective measurement of exposure. METHODS AND RESULTS: Among 3326 US men and women >=65 years of age and free of AF or heart failure at baseline, plasma phospholipid levels of eicosapentaenoic acid, docosapentaenoic acid, and docosahexaenoic acid were measured at baseline by use of standardized methods. Incident AF (789 cases) was identified prospectively from hospital discharge records and study visit ECGs during 31 169 person-years of follow-up (1992-2006). In multivariable Cox models adjusted for other risk factors, the relative risk in the top versus lowest quartile of total n-3 PUFAs (eicosapentaenoic acid+docosapentaenoic acid+docosahexaenoic acid) levels was 0.71 (95% confidence interval, 0.57-0.89; P for trend=0.004) and of DHA levels was 0.77 (95% confidence interval, 0.62-0.96; P for trend=0.01). Eicosapentaenoic acid and docosapentaenoic acid levels were not significantly associated with incident AF. Evaluated nonparametrically, both total n-3 PUFAs and docosahexaenoic acid showed graded and linear inverse associations with incidence of AF. Adjustment for intervening events such as heart failure or myocardial infarction during follow-up did not appreciably alter results. CONCLUSIONS: In older adults, higher circulating total long-chain n-3 PUFA and docosahexaenoic acid levels were associated with lower risk of incident AF. These results highlight the need to evaluate whether increased dietary intake of these fatty acids could be effective for the primary prevention of AF.
SN  - 0009-7322
U2  - PMID: 22282329.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107999189
T1  - Atrial fibrillation in the 21st century: a current understanding of risk factors and primary prevention strategies.
AU  - Menezes, Arthur R
AU  - Lavie, Carl J
AU  - Dinicolantonio, James J
AU  - O'Keefe, James
AU  - Morin, Daniel P
AU  - Khatib, Sammy
AU  - Milani, Richard V
Y1  - 2013/04//
N1  - Accession Number: 107999189. Language: English. Entry Date: 20130719. Revision Date: 20150712. Publication Type: Journal Article. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 0405543. 
KW  - Atrial Fibrillation -- Etiology
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Preventive Health Care -- Methods
KW  - Age Factors
KW  - Alcohol Drinking
KW  - Diet
KW  - Exercise
KW  - Disease Susceptibility
KW  - Metabolic Syndrome X -- Complications
KW  - Risk Factors
KW  - Sex Factors
KW  - Sleep Apnea, Obstructive -- Complications
SP  - 394
EP  - 409
JO  - Mayo Clinic Proceedings
JF  - Mayo Clinic Proceedings
JA  - MAYO CLIN PROC
VL  - 88
IS  - 4
CY  - Philadelphia, Pennsylvania
PB  - Elsevier Inc.
AB  - Atrial fibrillation (AF) is the most common arrhythmia worldwide, and it has a significant effect on morbidity and mortality. It is a significant risk factor for stroke and peripheral embolization, and it has an effect on cardiac function. Despite widespread interest and extensive research on this topic, our understanding of the etiology and pathogenesis of this disease process is still incomplete. As a result, there are no set primary preventive strategies in place apart from general cardiology risk factor prevention goals. It seems intuitive that a better understanding of the risk factors for AF would better prepare medical professionals to initially prevent or subsequently treat these patients. In this article, we discuss widely established risk factors for AF and explore newer risk factors currently being investigated that may have implications in the primary prevention of AF. For this review, we conducted a search of PubMed and used the following search terms (or a combination of terms): atrial fibrillation, metabolic syndrome, obesity, dyslipidemia, hypertension, type 2 diabetes mellitus, omega-3 fatty acids, vitamin D, exercise toxicity, alcohol abuse, and treatment. We also used additional articles that were identified from the bibliographies of the retrieved articles to examine the published evidence for the risk factors of AF.
SN  - 0025-6196
AD  - Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School-The University of Queensland School of Medicine, New Orleans, LA.
U2  - PMID: 23541013.
DO  - 10.1016/j.mayocp.2013.01.022
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106930216
T1  - Atrial fibrillation: how best to use rate control and anticoagulation.
AU  - Feller DB
AU  - Grauer K
Y1  - 2002/04//2002 Apr 1
N1  - Accession Number: 106930216. Language: English. Entry Date: 20020614. Revision Date: 20150711. Publication Type: Journal Article; tables/charts. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 750110. 
KW  - Atrial Fibrillation -- Physiopathology
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Aspirin -- Therapeutic Use
KW  - Warfarin -- Therapeutic Use
KW  - Adrenergic Beta-Antagonists -- Therapeutic Use
KW  - Digoxin -- Therapeutic Use
KW  - Stroke -- Prevention and Control
SP  - 526
EP  - 531
JO  - Consultant (00107069)
JF  - Consultant (00107069)
JA  - CONSULTANT
VL  - 42
IS  - 4
CY  - Framingham, Massachusetts
PB  - United Business Media
AB  - Risk factors for atrial fibrillation (AF) include advanced age, valvular heart disease, and increased left atrial dimensions. AF is associated with significant morbidity and mortality, principally because of the increased incidence of thromboembolic events. The clinical presentation may vary from minimal or no symptoms to nonspecific manifestations such as palpitations, decreased exercise tolerance, or fatigue of recent onset. Once the patient is hemodynamically stable, the goals of management are rate control, relief of symptoms, and prevention of thromboembolic complications. Effective therapeutic options for immediate and long-term rate control include digoxin (for patients with AF and heart failure), calcium channel antagonists, and beta-blockers. Although rate control usually improves symptoms, it does not prevent ischemic stroke; long-term anticoagulation with warfarin is therefore required. Those at low risk may derive adequate protection from aspirin.
SN  - 0010-7069
AD  - Assistant Professor of Community Health and Family Medicine, University of Florida College of Medicine, Gainesville
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105451473
T1  - Atrial fibrillation: pathogenesis, medical-surgical management and dental implications.
AU  - Friedlander AH
AU  - Yoshikawa TT
AU  - Chang DS
AU  - Feliciano Z
AU  - Scully C
Y1  - 2009/02//
N1  - Accession Number: 105451473. Language: English. Entry Date: 20090501. Revision Date: 20150711. Publication Type: Journal Article; pictorial; research; systematic review; tables/charts. Note: For CE see pages 47-50. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Dental Care; Evidence-Based Practice. NLM UID: 7503060. 
KW  - Atrial Fibrillation -- Etiology
KW  - Atrial Fibrillation -- Therapy
KW  - Dental Care for Chronically Ill
KW  - Atrial Fibrillation -- Diagnosis
KW  - Atrial Fibrillation -- Epidemiology
KW  - Atrial Fibrillation -- Surgery
KW  - Computerized Literature Searching
KW  - Drug Interactions
KW  - Education, Continuing (Credit)
KW  - Heart -- Physiology
KW  - Heart -- Physiopathology
KW  - Interprofessional Relations
KW  - Medline
KW  - Stroke -- Prevention and Control
KW  - Systematic Review
KW  - Warfarin -- Therapeutic Use
KW  - Human
SP  - 167
EP  - 177
JO  - Journal of the American Dental Association (JADA)
JF  - Journal of the American Dental Association (JADA)
JA  - J AM DENT ASSOC
VL  - 140
IS  - 2
CY  - Chicago, Illinois
PB  - American Dental Association
AB  - BACKGROUND: Atrial fibrillation (AF) is a cardiac rhythm disturbance arising from disorganized electrical activity in the atria, and it is accompanied by an irregular and often rapid ventricular response. It is the most common clinically significant dysrhythmia in the general and older population. TYPES OF STUDIES REVIEWED: The authors conducted a MEDLINE search using the key terms 'atrial fibrillation,' 'epidemiology,' 'pathophysiology,' 'treatment' and 'dentistry.' They selected contemporaneous articles published in peer-reviewed journals and gave preference to articles reporting randomized controlled trials. CLINICAL IMPLICATIONS: The anticoagulant warfarin frequently is prescribed to prevent stroke caused by cardiogenic thromboemboli arising from stagnant blood in poorly contracting atria. Most dental procedures and a limited number of surgical procedures can be performed without altering warfarin dosage if the international normalized ratio value is within the therapeutic range of 2.0 to 3.0. Certain analgesic agents, antibiotic agents, antifungal agents and sedative hypnotics, however, should not be prescribed without consultation with the patient's physician because these medications may alter the patient's risk of hemorrhage and stroke. CONCLUSIONS: AF affects nearly 2.5 million Americans, most of who are older than 60 years. Consultation with the patient's physician to discuss the planned dental treatment often is appropriate, especially for people who frequently have comorbid diseases such as coronary artery disease, congestive heart failure, diabetes and thyrotoxicosis, which are treated with multiple drug regimens.
SN  - 0002-8177
AD  - Associate Chief of Staff, Director of Graduate Medical Education, VA Greater Los Angeles Healthcare System, Director of Quality Assurance, Hospital Dental Service, University of California Los Angeles Medical Center, 11301 Wilshire Blvd., Los Angeles, CA 90073; arthur.friedlander@med.va.gov
U2  - PMID: 19188413.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104951486
T1  - Atrial substrate properties and outcome of catheter ablation in patients with paroxysmal atrial fibrillation associated with diabetes mellitus or impaired fasting glucose.
AU  - Chao TF
AU  - Suenari K
AU  - Chang SL
AU  - Lin YJ
AU  - Lo LW
AU  - Hu YF
AU  - Tuan TC
AU  - Tai CT
AU  - Tsao HM
AU  - Li CH
AU  - Ueng KC
AU  - Wu TJ
AU  - Chen SA
Y1  - 2010/12//
N1  - Accession Number: 104951486. Language: English. Entry Date: 20110204. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0207277. 
KW  - Atrial Fibrillation -- Physiopathology
KW  - Blood Glucose -- Metabolism
KW  - Body Surface Potential Mapping -- Methods
KW  - Catheter Ablation
KW  - Diabetes Mellitus -- Blood
KW  - Glucose Intolerance -- Blood
KW  - Tachycardia -- Physiopathology
KW  - Adult
KW  - Aged
KW  - Aged, 80 and Over
KW  - Atrial Fibrillation -- Complications
KW  - Atrial Fibrillation -- Surgery
KW  - Fasting
KW  - Female
KW  - Prospective Studies
KW  - Glucose Intolerance -- Complications
KW  - Heart Atrium -- Physiopathology
KW  - Heart Atrium -- Surgery
KW  - Human
KW  - Diagnostic Imaging
KW  - Male
KW  - Middle Age
KW  - Prognosis
KW  - Recurrence
KW  - Tachycardia -- Complications
KW  - Tachycardia -- Surgery
KW  - Young Adult
SP  - 1615
EP  - 1620
JO  - American Journal of Cardiology
JF  - American Journal of Cardiology
JA  - AM J CARDIOL
VL  - 106
IS  - 11
CY  - Philadelphia, Pennsylvania
PB  - Elsevier Inc.
SN  - 0002-9149
AD  - Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Clinical Medicine and Cardiovascular Research Center, National Yang-Ming University, Taipei, Taiwan.
U2  - PMID: 21094363.
DO  - 10.1016/j.amjcard.2010.07.038
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103899920
T1  - Avoiding afib hospitalizations.
Y1  - 2014/10//
N1  - Accession Number: 103899920. Language: English. Entry Date: 20141001. Revision Date: 20150710. Publication Type: Journal Article; pictorial. Journal Subset: Consumer Health; Editorial Board Reviewed; Peer Reviewed; USA. Special Interest: Consumer Health. NLM UID: 9425764. 
KW  - Hospitalization
KW  - Atrial Fibrillation -- Diagnosis
KW  - Academic Medical Centers
KW  - Atrial Fibrillation -- Physiopathology
KW  - Patient Education
KW  - Health Knowledge -- Evaluation
KW  - Heart Diseases
KW  - Heart -- Anatomy and Histology
KW  - United States
KW  - Health Care Costs
KW  - Anticoagulants -- Administration and Dosage
KW  - Diet -- Evaluation
KW  - Smoking Cessation
KW  - Stress -- Therapy
KW  - Catheter Ablation
KW  - Atrial Fibrillation -- Therapy
SP  - 3
EP  - 3
JO  - Harvard Health Letter
JF  - Harvard Health Letter
JA  - HARV HEALTH LETT
VL  - 39
IS  - 12
CY  - Stamford, Connecticut
PB  - Harvard Health Publications
SN  - 1052-1577
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103899920&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 110556245
T1  - Better a-fib treatment.
AU  - Sanders, Prashanthan
Y1  - 2015/11//
N1  - Accession Number: 110556245. Language: English. Entry Date: 20151028. Revision Date: 20151028. Publication Type: Article. Journal Subset: Consumer Health; USA. NLM UID: 9891730. 
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Exercise
SP  - 7
EP  - 7
JO  - Bottom Line Health
JF  - Bottom Line Health
JA  - BOTTOM LINE HEALTH
VL  - 29
IS  - 11
CY  - Greenwich, Connecticut
PB  - Health Confidential
SN  - 1092-0129
AD  - Director, Centre for Heart Rhythm Disorders, University of Adelaide, Australia
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 110719203
T1  - Bipolar radiofrequency catheter ablation for refractory perimitral flutter: a case report.
AU  - Yamagata, Kenichiro
AU  - Wichterle, Dan
AU  - Peichl, Petr
AU  - Aldhoon, Bashar
AU  - Čihák, Robert
AU  - Kautzner, Josef
Y1  - 2015/10/28/
N1  - Accession Number: 110719203. Language: English. Entry Date: In Process. Revision Date: 20160517. Publication Type: journal article. Journal Subset: Biomedical; Europe; UK & Ireland. Instrumentation: Motricity Index; Clinical Decision Making in Nursing Scale (CDMNS) (Jenkins). NLM UID: 100968539. 
KW  - Atrial Fibrillation -- Surgery
KW  - Catheter Ablation -- Methods
KW  - Mitral Valve -- Surgery
KW  - Recurrence
KW  - Male
KW  - Middle Age
KW  - Treatment Outcomes
KW  - Scales
SP  - 1
EP  - 6
JO  - BMC Cardiovascular Disorders
JF  - BMC Cardiovascular Disorders
JA  - BMC CARDIOVASC DISORD
VL  - 15
PB  - BioMed Central
AB  - Background: Mitral isthmus is often targeted as a part of stepwise approach during radiofrequency ablation for persistent atrial ablation. Acute success rate in achieving the mitral isthmus block is only modest, late reconduction rate is relatively high and, consequently, incomplete lesion may be proarrhythmic. We describe the first-in-man experience with successful MI ablation by bipolar RF energy delivery.Case Presentation: A 64-year-old caucasian man after two previous ablation procedures for drug resistant atrial fibrillation in recent four years, which included pulmonary vein isolation and linear left atrial lesions, was referred for the treatment of recurrent perimitral flutter. Despite the third attempt to create bidirectional block at the mitral isthmus region, we were not even able to stop the arrhythmia by aggressive unipolar radiofrequency ablation both from the left atrium and coronary sinus, because of deeply embedded slow conducting channel probably around the vein of Marshall. Arrhythmia was finally terminated and the block was achieved by bipolar radiofrequency ablation between two irrigated-tip catheters positioned at the left atrial endocardium and contralaterally inside the coronary sinus.Conclusion: Bipolar radiofrequency energy delivery can be an option for ablation of perimitral flutter resistant to standard unipolar radiofrequency ablation. This may improve clinical outcome of patients undergoing non-pharmacological treatment for persistent atrial fibrillation. The safety and efficacy of this technique has to be confirmed in future studies.
SN  - 1471-2261
AD  - Department of Cardiology, Institute for Clinical and Experimental Medicine (IKEM), Vídenská 1958/9, Prague 140 21, Czech Republic
U2  - PMID: 26510461.
DO  - 10.1186/s12872-015-0132-z
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104023467
T1  - Bleeding Risk Factors Affecting Warfarin Therapy in the Elderly With Atrial Fibrillation.
AU  - Darnell, Stan W.
AU  - Davis, Stephanie C.
AU  - Whitcomb, John J.
AU  - Manfredi, Joseph A.
AU  - McLaurin, Brent T.
Y1  - 2014/03//Mar/Apr2014
N1  - Accession Number: 104023467. Language: English. Entry Date: 20140507. Revision Date: 20150710. Publication Type: Journal Article; research; systematic review. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Special Interest: Critical Care; Evidence-Based Practice. NLM UID: 8211489. 
KW  - Atrial Fibrillation -- Drug Therapy -- In Old Age
KW  - Warfarin -- Adverse Effects -- In Old Age
KW  - Hemorrhage -- Risk Factors -- In Old Age
KW  - Hemorrhage -- Chemically Induced -- In Old Age
KW  - Aged
KW  - Warfarin -- Therapeutic Use -- In Old Age
KW  - Atrial Fibrillation -- Physiopathology
KW  - Human
KW  - Systematic Review
KW  - CINAHL Database
KW  - Medline
KW  - Stroke -- Prevention and Control
KW  - Aspirin -- Therapeutic Use
KW  - Warfarin -- Pharmacodynamics
KW  - Drug Interactions
KW  - Vitamin K
KW  - Advanced Practice Nurses
KW  - Atrial Fibrillation -- Epidemiology
KW  - Incidence
SP  - 57
EP  - 63
JO  - Dimensions of Critical Care Nursing
JF  - Dimensions of Critical Care Nursing
JA  - DCCN
VL  - 33
IS  - 2
CY  - Philadelphia, Pennsylvania
PB  - Springhouse Corporation
AB  - Purpose: Inadequate anticoagulation among elderly individuals with atrial fibrillation (AF) is a common problem. This synthesis of the literature review describes the pathophysiology of AF, explains the mechanism of action of warfarin (Coumadin), identifies factors that contribute to warfarin (Coumadin)-associated bleeding in the elderly population, and explores alternatives to warfarin (Coumadin) therapy. Implications for advanced practice nurse practice, education, and research will be discussed. Methods: A literature search was conducted using Academic Search Premier, CINAHL Plus with Full Text, and Medline from 1999 to 2012. Search terms included warfarin (Coumadin), warfarin (Coumadin) genetics, diet, interactions, bleeding, atrial fibrillation, genetics, anticoagulation clinic, dabigatran, apixaban, rivaroxaban, and elderly. Results: The literature indicates that the potential bleeding risk associated with warfarin (Coumadin) therapy limits its use in the elderly population. However, some studies have found warfarin (Coumadin) to be more effective than aspirin in preventing stroke. The safety profiles of both medications were comparable; also, effective alternatives to warfarin (Coumadin) that do not require routine testing are now available. Conclusions: Atrial fibrillation increases the probability of an embolic stroke, especially for the elderly population. Stroke risk and bleeding risk tools, in conjunction with patient preference, determine the best stroke prevention treatment. Anticoagulant clinics manage long-term warfarin (Coumadin) therapy effectively. Newer anticoagulants offer effective alternatives to warfarin (Coumadin) therapy.
SN  - 0730-4625
AD  - Adult-gerontology nurse practitioner, Southeastern Neurosurgical & Spine Institute, Greenville Health System, South Carolina
AD  - Graduate coordinator, Clemson University School of Nursing, South Carolina; Associate professor, Clemson University School of Nursing, South Carolina
AD  - Second degree coordinator, Clemson University School of Nursing, South Carolina; Assistant professor, Clemson University School of Nursing, South Carolina
AD  - Clinical cardiac electrophysiologist, AnMed Health Arrhythmia Specialists, Anderson, South Carolina
AD  - Cardiologist, Anderson Heart, AnMed Health, Anderson, South Carolina; Director, Research Division, Anderson Heart and AnMed Research Division
U2  - PMID: 24496251.
DO  - 10.1097/DCC.0000000000000022
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104023467&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103825315
T1  - Body fat, body fat distribution, lean body mass and atrial fibrillation and flutter. A Danish cohort study.
AU  - Frost, Lars
AU  - Benjamin, Emelia J
AU  - Fenger-Grøn, Morten
AU  - Pedersen, Asger
AU  - Tjønneland, Anne
AU  - Overvad, Kim
Y1  - 2014/06//
N1  - Accession Number: 103825315. Language: English. Entry Date: 20150206. Revision Date: 20150710. Publication Type: Journal Article; research. Journal Subset: Biomedical; USA. NLM UID: 101264860. 
KW  - Adipose Tissue
KW  - Arrhythmia -- Epidemiology
KW  - Atrial Fibrillation -- Epidemiology
KW  - Adipose Tissue Distribution
KW  - Body Mass Index
KW  - Body Height
KW  - Body Weight
KW  - Denmark
KW  - Electric Impedance
KW  - Energy Intake
KW  - Female
KW  - Prospective Studies
KW  - Surveys
KW  - Human
KW  - Incidence
KW  - Male
KW  - Middle Age
KW  - Risk Factors
KW  - Socioeconomic Factors
KW  - Waist Circumference
KW  - Waist-Hip Ratio
SP  - 1546
EP  - 1552
JO  - Obesity (19307381)
JF  - Obesity (19307381)
JA  - OBESITY (19307381)
VL  - 22
IS  - 6
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 1930-7381
AD  - Department of Medicine, Silkeborg Hospital & Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.
U2  - PMID: 24436019.
DO  - 10.1002/oby.20706
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103825315&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106088664
T1  - Bridging the gap between basic and clinical electrophysiology: what can be learned from monophasic action potential recordings?
AU  - Franz M
Y1  - 1994/08//
N1  - Accession Number: 106088664. Language: English. Entry Date: 20081219. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9010756. 
KW  - Action Potentials -- Drug Effects
KW  - Heart -- Physiology
KW  - Animals
KW  - Antiarrhythmia Agents -- Pharmacodynamics
KW  - Arrhythmia -- Etiology
KW  - Defibrillators, Implantable
KW  - Heart -- Drug Effects
KW  - Hemodynamics
KW  - Myocardial Ischemia -- Physiopathology
KW  - Neural Conduction -- Drug Effects
SP  - 699
EP  - 710
JO  - Journal of Cardiovascular Electrophysiology
JF  - Journal of Cardiovascular Electrophysiology
JA  - J CARDIOVASC ELECTROPHYSIOL
VL  - 5
IS  - 8
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - With rapid advances occuring in both basic and clinical electrophysiology, the gap between the two disciplines appears to be widening rather than narrowing. In most instances, we cannot apply the knowledge derived from cellular studies directly to clinical practice. Monophasic action potential (MAP) recording by contact electrode technique allows us to measure basic electrophysiological phenomena in the human heart and thus provides an important bridge between basic and clinical electrophysiology. MAP recordings produce the time course of cellular repolarization during cycle length changes and antiarrhythmic drug administration, lending insights into use dependency and reverse use dependency of antiarrhythmic drug effects in the clinical electrophsiology laboratory. The ability to deliver electrical stimuli at the MAP recording site further allows one to investigate drug-induced postrepolarixation refractoriness. MAP recordings provide precise local activation times, important for mapping of abnormal ventricular activation, and detect areas of abnormal repolarization due to ischemia or scarring. MAP recordings are uniquely suited to detect early and delayed afterdepolarizations in the human heart, thereby helping to unravel the arrhythmia mechanisms in the long QT syndrome. By embedding the MAP electrode in a radiofrequency electrode, arrhythmogenic foci may be both detected and ablated. In many instances, MAP recordings are more accurate than ECG tracings in defining and distinguishing ventricular fibrillation and ventricular tachycardia. This can he of clinical importance during testing of the implantable cardioverter/defibrillator. An area of growing interest is stretch-activated arrhythmias. Here, MAP recordings are of particular value because no other method is available to record mechanically induced electrophysiological changes in the vigorously beating heart. It can be expected that MAP recordings will, in the future, provide this Important bridge between 'cell and bedside' also in atrial tachyarrhythmias, such as in atrial fibrillation and flutter.
SN  - 1045-3873
U2  - PMID: 7804522.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106088664&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106636359
T1  - Caffeine and arrhythmia.
AU  - Katan MB
AU  - Schouten E
Y1  - 2005/03//
N1  - Accession Number: 106636359. Language: English. Entry Date: 20050527. Revision Date: 20150819. Publication Type: Journal Article; commentary; editorial. Original Study: Frost L, Vestergaard P. Caffeine and risk of atrial fibrillation or flutter: the Danish Diet, Cancer, and Health Study. (AM J CLIN NUTR) Mar2005; 81 (3): 578-582. Journal Subset: Allied Health; Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 0376027. 
KW  - Caffeine
KW  - Diet
KW  - Arrhythmia
KW  - Atrial Fibrillation
KW  - Atrial Flutter
SP  - 539
EP  - 540
JO  - American Journal of Clinical Nutrition
JF  - American Journal of Clinical Nutrition
JA  - AM J CLIN NUTR
VL  - 81
IS  - 3
CY  - Bethesda, Maryland
PB  - American Society for Nutrition
SN  - 0002-9165
AD  - Wageningen Centre for Food Sciences and Wageningen University, Division of Human Nutrition, Bomenweg 2, 6703 HD Wageningen, Netherlands; wcfs1@wur.nl
U2  - PMID: 15755819.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106636359&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106636374
T1  - Caffeine and risk of atrial fibrillation or flutter: the Danish Diet, Cancer, and Health Study.
AU  - Frost L
AU  - Vestergaard P
Y1  - 2005/03//
N1  - Accession Number: 106636374. Language: English. Entry Date: 20050527. Revision Date: 20150819. Publication Type: Journal Article; research; tables/charts. Commentary: Katan MB, Schouten E. Caffeine and arrhythmia. (AM J CLIN NUTR) Mar2005; 81 (3): 539-540. Journal Subset: Allied Health; Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Grant Information: Supported by a senior research fellowship from the Danish Medical Research Council (grant no. 22-02-0582). NLM UID: 0376027. 
KW  - Caffeine
KW  - Diet
KW  - Atrial Fibrillation
KW  - Atrial Flutter
KW  - Tea
KW  - Coffee
KW  - Carbonated Beverages
KW  - Cacao
KW  - Prospective Studies
KW  - Middle Age
KW  - Denmark
KW  - Descriptive Statistics
KW  - Male
KW  - Female
KW  - Confidence Intervals
KW  - Body Weights and Measures
KW  - Questionnaires
KW  - Nutritional Assessment
KW  - Data Analysis Software
KW  - International Classification of Diseases
KW  - Record Review
KW  - Linear Regression
KW  - Cox Proportional Hazards Model
KW  - Body Mass Index -- Evaluation
KW  - Spearman's Rank Correlation Coefficient
KW  - Two-Tailed Test
KW  - Funding Source
KW  - Human
SP  - 578
EP  - 582
JO  - American Journal of Clinical Nutrition
JF  - American Journal of Clinical Nutrition
JA  - AM J CLIN NUTR
VL  - 81
IS  - 3
CY  - Bethesda, Maryland
PB  - American Society for Nutrition
AB  - BACKGROUND: It is not known whether the consumption of caffeine is associated with excess risk of atrial fibrillation. OBJECTIVE: We evaluated the risk of atrial fibrillation or flutter in association with daily consumption of caffeine from coffee, tea, cola, cocoa, and chocolate. DESIGN: We prospectively examined the association between the amount of caffeine consumed per day and the risk of atrial fibrillation or flutter among 47 949 participants (x age: 56 y) in the Danish Diet, Cancer, and Health Study. Subjects were followed in the Danish National Registry of Patients and in the Danish Civil Registration System. The consumption of caffeine was analyzed by quintiles with Cox proportional-hazard models. RESULTS: During follow-up (x: 5.7 y), atrial fibrillation or flutter developed in 555 subjects (373 men and 182 women). When the lowest quintile of caffeine consumption was used as a reference, the adjusted hazard ratios (95% CIs) in quintiles 2, 3, 4, and 5 were 1.12 (0.87, 1.44), 0.85 (0.65, 1.12), 0.92 (0.71, 1.20), and 0.91 (0.70, 1.19), respectively. CONCLUSION: Consumption of caffeine was not associated with risk of atrial fibrillation or flutter. Copyright © 2005 American Society for Clinical Nutrition
SN  - 0002-9165
AD  - Department of Cardiology, Aarhus Sygehus, Aarhus University Hospital, DK-8000 Aarhus C, Denmark; Lars.Frost@as.aaa.dk
U2  - PMID: 15755825.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106636374&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105776203
T1  - Cardiology patient page. A patient's guide to living with atrial fibrillation.
AU  - Shea JB
AU  - Sears SF
Y1  - 2008/05/20/
N1  - Accession Number: 105776203. Language: English. Entry Date: 20080801. Revision Date: 20150711. Publication Type: Journal Article; review; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Public Health. NLM UID: 0147763. 
KW  - Atrial Fibrillation
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Atrial Fibrillation -- Symptoms
KW  - Patient Education
KW  - Anticoagulants
KW  - Atrial Fibrillation -- Diagnosis
KW  - Catheter Ablation
KW  - Diet
KW  - Drugs, Prescription
KW  - Exercise
KW  - Life Style
SP  - e340
EP  - 3
JO  - Circulation
JF  - Circulation
JA  - CIRCULATION
VL  - 117
IS  - 20
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
SN  - 0009-7322
AD  - Brigham and Women's Hospital, Cardiovascular Division, 75 Francis St, Boston, MA 02115, USA. jshea@partners.org
U2  - PMID: 18490529.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105776203&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - GEN
ID  - 111740066
T1  - Cardiovascular Benefits of the Mediterranean Diet Are Driven by Stroke Reduction and Possibly by Decreased Atrial Fibrillation Incidence.
AU  - Geisler, Benjamin P.
Y1  - 2016/01//
N1  - Accession Number: 111740066. Language: English. Entry Date: 20160507. Revision Date: 20160507. Publication Type: commentary. Journal Subset: Biomedical; USA. NLM UID: 0267200. 
KW  - Mediterranean Diet
KW  - Cardiovascular Diseases -- Prevention and Control
SP  - e11
EP  - e11
JO  - American Journal of Medicine
JF  - American Journal of Medicine
JA  - AM J MED
VL  - 129
IS  - 1
PB  - Excerpta Medica Publishing Group
SN  - 0002-9343
AD  - NYU School of Medicine, New York
U2  - PMID: 26703006.
DO  - 10.1016/j.amjmed.2015.04.046
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=111740066&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107941205
T1  - Cardiovascular Disease in Women: A Nurse Practitioner's Guide to Prevention.
AU  - Roberts, Mary Ellen E.
AU  - Davis, Leslie L.
Y1  - 2013/11//Nov/Dec2013
N1  - Accession Number: 107941205. Language: English. Entry Date: 20131204. Revision Date: 20150818. Publication Type: Journal Article; tables/charts. Journal Subset: Blind Peer Reviewed; Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Advanced Nursing Practice; Evidence-Based Practice; Women's Health. NLM UID: 101264817. 
KW  - Cardiovascular Diseases -- Prevention and Control
KW  - Women's Health
KW  - Advanced Nursing Practice
KW  - Female
KW  - Risk Assessment
KW  - Physical Examination
KW  - Smoking Cessation
KW  - Hyperlipidemia -- Drug Therapy
KW  - Life Style Changes
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Patient Compliance
KW  - Nurse Practitioners
KW  - Rehabilitation, Cardiac
KW  - Weight Control
SP  - 679
EP  - 687
JO  - Journal for Nurse Practitioners
JF  - Journal for Nurse Practitioners
JA  - J NURSE PRACT
VL  - 9
IS  - 10
CY  - Philadelphia, Pennsylvania
PB  - Elsevier Inc.
AB  - Cardiovascular disease (CVD) is the number 1 cause of death in women, accounting for about 1 in 3 deaths. This article reviews the 2011 American Heart Association effectiveness-based guidelines for CVD prevention in women. Risk assessment, prevention, and management of risks through lifestyle changes and pharmacotherapy are discussed. The article concludes with implications for nurse practitioners on ways to improve cardiovascular health among women in their practice.
SN  - 1555-4155
AD  - Assistant professor and director, doctorate of nursing practice program at Seton Hall University and an adult nurse practitioner at Salerno Medical Associates in South Orange, NJ
AD  - Assistant professor of nursing, School of Nursing, University of North Carolina in Greensboro
DO  - 10.1016/j.nurpra.2013.08.018
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107941205&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105468745
T1  - Cardiovascular risk factors and incident Alzheimer disease: a systematic review of the literature.
AU  - Purnell C
AU  - Gao S
AU  - Callahan CM
AU  - Hendrie HC
AU  - Purnell, Christianna
AU  - Gao, Sujuan
AU  - Callahan, Christopher M
AU  - Hendrie, Hugh C
Y1  - 2009/01//Jan-Mar2009
N1  - Accession Number: 105468745. Language: English. Entry Date: 20090605. Revision Date: 20160517. Publication Type: journal article; research; systematic review. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Evidence-Based Practice. Grant Information: P30 AG10133/AG/NIA NIH HHS/United States. NLM UID: 8704771. 
KW  - Alzheimer's Disease -- Complications
KW  - Cardiovascular Diseases -- Complications
KW  - PubMed
KW  - Risk Factors
KW  - Human
SP  - 1
EP  - 10
JO  - Alzheimer Disease & Associated Disorders
JF  - Alzheimer Disease & Associated Disorders
JA  - ALZHEIMER DIS ASSOC DISORD
VL  - 23
IS  - 1
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - Objective: The purpose of this study was to conduct a systematic review of the literature of cardiovascular factors pertaining to incident Alzheimer disease (AD).Methods: A systematic literature review was conducted of all studies of cardiovascular risk factors for incident AD listed in PubMed in English from 2000 to 2007. Risk factors included hypertension, diabetes, exercise, alcohol intake, smoking, B complex vitamins, homocysteine, stroke, atrial fibrillation, apolipoprotein E (APOE), lipids, and diet. Inclusion criteria consisted of diagnoses of incident AD and longitudinal studies with cohorts of 500 or more.Results: Individual clinically defined risk factors such as hypertension and diabetes were not significantly associated with increased risk for AD. The strength of the association for hypertension could be considerably strengthened by changing criteria such as midlife measurements or using higher cutoffs for systolic blood pressure. APOE epsilon4 was the most consistent risk factor. Interactions between risk factors modify risk particularly for hypertension and diabetes. Interactions modifying risk were also found for exercise and physical function, APOE epsilon4, diabetes, and cholesterol.Conclusions: In this review, the evidence that single clinically defined cardiovascular risk factors are significantly associated with incident AD is inconsistent at best. The strength of the association of cardiovascular risk factors and AD can be influenced greatly by changing the parameters of measurement of risk factors and by identifying interactions between the factors.
SN  - 0893-0341
AD  - Regenstrief Institute Inc, Indiana University School of Medicine, Indianapolis, IN, USA
AD  - Regenstrief Institute Inc, Indiana University School of Medicine, Indianapolis, IN, USA.
U2  - PMID: 18703981.
DO  - 10.1097/WAD.0b013e318187541c
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106038987
T1  - Cardioversion of atrial fibrillation and subsequent maintenance of sinus rhythm.
AU  - Van Gelder IC
AU  - Crijns HJ
Y1  - 1997/10/15/
N1  - Accession Number: 106038987. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Allied Health; Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7803944. 
SP  - 2675
EP  - 2683
JO  - Pacing & Clinical Electrophysiology
JF  - Pacing & Clinical Electrophysiology
JA  - PACING CLIN ELECTROPHYSIOL
VL  - 20
IS  - 10P2
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - This article gives an overview of electrical cardioversion of AF and includes the discussion of newer strategies. DC external cardioversion is highly effective and carries a low risk of complications. Other approaches, like transesophageal cardioversion and high energy internal cardioversion, may improve the acute success rate but do not enhance long-term maintenance of sinus rhythm compared to external cardioversion. An atrial defibrillator may have important advantages which relate to the fact that the duration and possibly also the number of AF episodes become reduced. Supposedly, shortening the attacks of AF may exert an antiarrhythmic effect by limiting electrical, anatomical, and neurohumoral remodeling. So far, low energy biatrial defibrillation using an atrial defibrillator seems to be effective and safe (i.e., does not induce ventricular arrhythmias). However, discomfort limits its tolerability in clinical practice. Future improvement of leads and light sedation that is easy to administer may overcome this problem. In the second part of this overview, the probability of AF recurrence using a serial cardioversion approach is discussed. In middle-aged patients with a fair exercise tolerance and an arrhythmia duration < than 36 months this approach may be worthwhile. Young patients (age < 57 years) with an arrhythmia duration < 3 months and without hypertension may be cured from the arrhythmia with a single shock and without the institution of antiarrhythmic drugs. However, the serial electrical cardioversion approach is unlikely to succeed in elderly patients with a duration of AF exceeding 36 months and a poor exercise tolerance (NYHA Functional Class III or IV).
SN  - 0147-8389
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105085655
T1  - Case report. Elevated International Normalized Ratio associated with concomitant warfarin and erlotinib.
AU  - Thomas KS
AU  - Billingsley A
AU  - Amarshi N
AU  - Nair BA
Y1  - 2010/09//9/1/2010
N1  - Accession Number: 105085655. Language: English. Entry Date: 20100917. Revision Date: 20150711. Publication Type: Journal Article; case study; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Adenocarcinoma -- Drug Therapy
KW  - Antineoplastic Agents -- Adverse Effects
KW  - Carcinoma, Non-Small-Cell Lung -- Drug Therapy
KW  - Drug Therapy, Combination -- Adverse Effects
KW  - Receptors, Cell Surface -- Antagonists and Inhibitors
KW  - Warfarin -- Adverse Effects
KW  - Diarrhea -- Chemically Induced
KW  - Exanthema -- Chemically Induced
KW  - Male
KW  - Middle Age
KW  - Warfarin -- Administration and Dosage
SP  - 1426
EP  - 1429
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 67
IS  - 17
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
AB  - PURPOSE: The case of a patient who developed elevated International Normalized Ratio (INR) values after concomitant administration of warfarin and erlotinib is reported. SUMMARY: A 47-year-old Caucasian man with a history of atrial fibrillation, anxiety, and a 40-pack-year smoking history was diagnosed with advanced, moderately differentiated adenocarcinoma of the lung. Soon after being diagnosed with non-small-cell lung cancer, warfarin was initiated for the treatment of a venous thromboembolism. The patient's warfarin dosage was adjusted to reach a target INR of 2-3. His INR was relatively stable (2.1-3.2) for at least eight weeks before erlotinib was added to the chemotherapy regimen. The patient developed a well-disseminated rash and diarrhea soon after starting erlotinib. Seven days after the initiation of erlotinib therapy, the patient's INR value increased from 2.8 to 5.3, with no concurrent changes in warfarin dosage, other medications, or diet. After withholding two doses of warfarin, the patient's INR value increased to 9.1, and the patient developed an elbow hematoma. His anticoagulation was rapidly reversed with the administration of subcutaneous phytonadione. The patient elected to discontinue erlotinib nine days after its initiation. The next day, his INR value was 2.4. The patient returned to the hematology-oncology clinic for follow-up two days later, where his INR was found to be 0.9. CONCLUSION: Concomitant administration of erlotinib and warfarin resulted in an increase in INR values in a 47-year-old man with advanced lung cancer.
SN  - 1079-2082
AD  - Residency Program Director and Clinical Pharmacist, Pharmacy Service, Central Arkansas Veterans Healthcare System (CAVHS), Little Rock, AR; kelly.thomas@va.gov
U2  - PMID: 20720241.
DO  - 10.2146/ajhp090202
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105738587
T1  - Challenges of implementing a feasibility study of acupuncture in acute and critical care settings.
AU  - Lindquist R
AU  - Sendelbach S
AU  - Windenburg DC
AU  - VanWormer A
AU  - Treat-Jacobson D
AU  - Chose D
Y1  - 2008/04//Apr-Jun2008
N1  - Accession Number: 105738587. Language: English. Entry Date: 20080613. Revision Date: 20150818. Publication Type: Journal Article; research; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Advanced Nursing Practice; Critical Care. Grant Information: Supported by the National Institute of Nursing Research (grant P20 NR008992). NLM UID: 101269322. 
KW  - Acupuncture
KW  - Coronary Artery Bypass
KW  - Critical Care Nursing
KW  - Critically Ill Patients
KW  - Surgical Patients
KW  - Clinical Nursing Research
KW  - Communication
KW  - Consent (Research)
KW  - Funding Source
KW  - Institutional Review
KW  - Intensive Care Units
KW  - Minnesota
KW  - Pilot Studies
KW  - Research Subject Recruitment
KW  - Time Factors
KW  - Human
SP  - 202
EP  - 210
JO  - AACN Advanced Critical Care
JF  - AACN Advanced Critical Care
JA  - AACN ADV CRIT CARE
VL  - 19
IS  - 2
CY  - Alisa Veijo, California
PB  - American Association of Critical-Care Nurses
AB  - A majority of people in the United States use complementary and alternative therapies, and this use is increasing. With the increasing interest, providers must evaluate potential risks and benefits of these therapies. This article describes challenges of a feasibility study of acupuncture as a potential therapeutic adjunct to prevent atrial fibrillation following coronary artery bypass graft surgery. Institutional review board approval, consent logistics, implementation issues, and rapid changes in clinical practice were the primary challenges faced. Unique technological features of the institution helped address these challenges. The study protocol was acceptable to staff, patients, and family and was considered safe for these patients. However, the protocol was not feasible as designed; therefore, the efficacy of acupuncture could not be determined. Continued research is needed to evaluate the effectiveness of acupuncture to prevent atrial fibrillation following coronary artery bypass graft surgery. Recommendations for future studies of complementary and alternative therapies in acute and critical care settings are offered.
SN  - 1559-7768
AD  - Professor, University of Minnesota School of Nursing, 5-140 WDH, 308 Harvard St SE, Minneapolis, MN 55455; lindq002@umn.edu
U2  - PMID: 18560289.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105738587&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109766310
T1  - Chocolate consumption and risk of heart failure in the Physicians' Health Study.
AU  - Petrone, Andrew B
AU  - Gaziano, J Michael
AU  - Djoussé, Luc
Y1  - 2014/12//
N1  - Accession Number: 109766310. Language: English. Entry Date: 20150821. Revision Date: 20160221. Publication Type: journal article; research. Journal Subset: Biomedical; Blind Peer Reviewed; Continental Europe; Europe; Expert Peer Reviewed; Peer Reviewed. Instrumentation: Food Frequency Questionnaire (FFQ). Grant Information: R01 HL034595/HL/NHLBI NIH HHS/United States. NLM UID: 100887595. 
KW  - Cacao
KW  - Candy
KW  - Heart Failure -- Epidemiology
KW  - Physicians -- Statistics and Numerical Data
KW  - Aged
KW  - Aged, 80 and Over
KW  - Aspirin -- Administration and Dosage
KW  - Blood Pressure -- Drug Effects
KW  - Cox Proportional Hazards Model
KW  - Flavonoids -- Administration and Dosage
KW  - Heart Failure -- Prevention and Control
KW  - Human
KW  - Male
KW  - Middle Age
KW  - Prospective Studies
KW  - Questionnaires
KW  - Risk Factors
KW  - Surveys
KW  - United States
SP  - 1372
EP  - 1376
JO  - European Journal of Heart Failure
JF  - European Journal of Heart Failure
JA  - EUR J HEART FAIL
VL  - 16
IS  - 12
CY  - Hoboken, New Jersey
PB  - John Wiley & Sons, Inc.
AB  - Aims: To test the hypothesis that chocolate consumption is associated with a lower risk of heart failure (HF).Methods and Results: We prospectively studied 20 278 men from the Physicians' Health Study. Chocolate consumption was assessed between 1999 and 2002 via a self-administered food frequency questionnaire and HF was ascertained through annual follow-up questionnaires with validation in a subsample. We used Cox regression to estimate multivariable adjusted relative risk of HF. During a mean follow-up of 9.3 years there were 876 new cases of HF. The mean age at baseline was 66.4 ± 9.2 years. Hazard ratios [95% confidence intervals (CI)] for HF were 1.0 (ref), 0.86 (0.72-1.03), 0.80 (0.66-0.98), 0.92 (0.74-1.13), and 0.82 (0.63-1.07), for chocolate consumption of less than 1/month, 1-3/week, 2-4/week, and 5+/week, respectively, after adjusting for age, body mass index (BMI), smoking, alcohol, exercise, energy intake, and history of atrial fibrillation (P for quadratic trend = 0.62). In a secondary analysis, chocolate consumption was inversely associated with risk of HF in men whose BMI was <25 kg/m(2) [HR (95% CI) = 0.59 (0.37-0.94) for consumption of 5+ servings/week, P for linear trend = 0.03) but not in those with BMI of 25+ kg/m(2) [HR (95% CI) = 1.01 (0.73-1.39), P for linear trend = 0.42, P for interaction = 0.17).Conclusions: Our data suggest that moderate consumption of chocolate might be associated with a lower risk of HF in male physicians.
SN  - 1388-9842
U2  - PMID: 25311633.
DO  - 10.1002/ejhf.180
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106947588
T1  - Chronic heart failure: 10 questions physicians often ask.
AU  - Tang WHW
AU  - Francis GS
Y1  - 2002/05//2002 May
N1  - Accession Number: 106947588. Language: English. Entry Date: 20020809. Revision Date: 20150711. Publication Type: Journal Article; questions and answers; tables/charts. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 750110. 
KW  - Heart Failure -- Diagnosis
KW  - Heart Failure -- Drug Therapy
KW  - Angiotensin-Converting Enzyme Inhibitors -- Administration and Dosage
KW  - Adrenergic Beta-Antagonists -- Administration and Dosage
KW  - Aldosterone -- Antagonists and Inhibitors
KW  - Prostheses and Implants
KW  - Defibrillators, Implantable
SP  - 678
EP  - 686
JO  - Consultant (00107069)
JF  - Consultant (00107069)
JA  - CONSULTANT
VL  - 42
IS  - 6
CY  - Framingham, Massachusetts
PB  - United Business Media
AB  - The key test in the initial evaluation is the standard echocardiogram. Elevated plasma levels of B-type natriuretic peptide strongly suggest underlying cardiac dysfunction in patients with symptoms of heart failure (HF). Consider angiotensin-converting enzyme (ACE) inhibitors and beta-blockers for all patients with HF, unless contraindicated. High doses of ACE inhibitors have not been shown to be more effective than lower ones; the goal is to reach target dosages comparable to those used in clinical trials. Angiotensin II receptor blockers do not reduce mortality more effectively than standard doses of ACE inhibitors, which remain first-line agents. Oral coagulation is not routinely recommended for patients with HF, although high-risk patients (such as those with atrial fibrillation) may benefit. Patient education, self-monitoring, and compliance with medication and dietary regimens are vital components of treatment.
SN  - 0010-7069
AD  - Senior Fellow in Cardiology, Cleveland Clinic Foundation
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105929794
T1  - Clinical acupuncture. When should pulse irregularities be referred to a cardiologist?
AU  - Robinson BH
Y1  - 2007/06//2007 Jun
N1  - Accession Number: 105929794. Language: English. Entry Date: 20080118. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Alternative/Complementary Therapies; USA. NLM UID: 100898733. 
KW  - Acupuncture
KW  - Arrhythmia
KW  - Arrhythmia -- Therapy
KW  - Referral and Consultation
KW  - Atrial Fibrillation
KW  - Atrial Flutter
KW  - Bradycardia
KW  - Cardiology
KW  - Heart Block
KW  - Premature Atrial Contractions
KW  - Premature Ventricular Contractions
KW  - Sick Sinus Syndrome
KW  - Tachycardia, Atrial
KW  - Tachycardia, Supraventricular
KW  - Tachycardia, Ventricular
SP  - 40
EP  - 41
JO  - Acupuncture Today
JF  - Acupuncture Today
JA  - ACUPUNCTURE TODAY
VL  - 8
IS  - 6
CY  - Huntington Beach, California
PB  - MPA Media
SN  - 1526-7784
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - THES
ID  - 109843058
T1  - Clinical correlates of silent ischemia in women with coronary artery disease.
AU  - Hockenberry BJ
Y1  - 1999/01//
N1  - Accession Number: 109843058. Language: English. Entry Date: 20050415. Revision Date: 20150923. Publication Type: Doctoral Dissertation; research. 
KW  - Ischemia -- Etiology
KW  - Ischemia -- Psychosocial Factors
KW  - Coronary Arteriosclerosis
KW  - Descriptive Research
KW  - Diaries
KW  - Electrocardiography
KW  - Female
KW  - Physical Activity
KW  - Videorecording
KW  - Human
SP  - 181 p
EP  - 181 p
JO  - Clinical Correlates of Silent Ischemia in Women With Coronary Artery Disease
JF  - Clinical Correlates of Silent Ischemia in Women With Coronary Artery Disease
PB  - Loyola University of Chicago
AB  - The purpose of this descriptive study was to examine (1) the incidence and characteristics of ambulatory ischemia in women with CAD; (2) clinical characteristics, typical activity patterns and emotional concerns in a representative sample of women with CAD; (3) whether exposure to specific emotions is linked to occurrences of ischemia; and (4) whether recall and tape recording examples of worry and family stress elicits ischemia. Twenty-six women with definite CAD or high probability of CAD 3 based on risk factors and stress test results underwent 24 hours of ambulatory ECG monitoring. The did not discontinue anti-anginal medications. Women were asked to record their physical activities and any feelings of anger, anxiety, worry or responses to family stress on diary forms. Using the standard ECG criteria for ischemia, ECG data were crosstabulated with diary data to determine how frequently ischemia might have been triggered by emotional or exercise stimuli. Results showed that 19 of 26 women Had one or more episodes of at least 1 mm. ST depression lasting at least one minute. The total ischemic time for 24 hours varied from no ischemia to 963 minutes of ischemia. Three subgroups of women were recognized with (1) no ischemia, (2) less than 200 minutes of ischemia in 24 hours, and (3) more than 200 minutes of ischemia in 24 hours. The extreme variability in results for ischemic time prevented using parametric statistics for analysis. Results showed that ischemia occurred within 10 minutes of low levels of physical activity in 39/104 (38%) of cases and 4/4 episodes of high physical activity resulted in ischemia. Low intensity emotional stress was accompanied by ischemia in 48/132 cases (36%) compared to 78/149 (52%) of episodes of high level emotional stress. Twelve of 26 women developed significant ST depression during the tape recording mental stress test. An additional 4/26 women developed ST segment changes that did not meet the criteria for ischemia. The majority of ischemic episodes occurred in the subgroup of women with extreme ischemic times. Exercise-induced ischemia, mental stress-induced ischemia, nocturnal ischemia and ischemia without any identifiable trigger were all prevalent in the extreme ischemic time group (n = 7) who tended to be older and sicker than the other women. In addition, they had resting ST depression or atrial fibrillation. The best explanation for the higher frequency and duration of ischemia is related to a higher level of disease severity in this subgroup of women with CAD.
SN  - 9780599308725
AV  - UMI Order AAI9930573
M1  - Ph.D.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107973416
T1  - Clinical decision-making for vitamin K-1 and K-2 deficiency and coronary artery calcification with warfarin therapy: are diet, factor Xa inhibitors or both the answer?
AU  - Wahlqvist, Mark L
AU  - Tanaka, Kiyoshi
AU  - Tzeng, Bing-Hsiean
Y1  - 2013/09//
N1  - Accession Number: 107973416. Language: English. Entry Date: 20131115. Revision Date: 20150712. Publication Type: Journal Article; case study. Journal Subset: Allied Health; Asia; Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed. Special Interest: Nutrition; Public Health. NLM UID: 9440304. 
KW  - Calcinosis -- Therapy
KW  - Coronary Arteriosclerosis -- Therapy
KW  - Diet
KW  - Blood Coagulation Factors -- Antagonists and Inhibitors
KW  - Vitamin K Deficiency -- Chemically Induced
KW  - Warfarin -- Adverse Effects
KW  - Calcinosis -- Etiology
KW  - Coronary Arteriosclerosis -- Etiology
KW  - Male
KW  - Middle Age
KW  - Arteriosclerosis -- Etiology
KW  - Arteriosclerosis -- Therapy
KW  - Vitamin K -- Administration and Dosage
KW  - Vitamin K Deficiency -- Complications
KW  - Vitamin K Deficiency -- Diet Therapy
KW  - Warfarin -- Therapeutic Use
SP  - 492
EP  - 496
JO  - Asia Pacific Journal of Clinical Nutrition
JF  - Asia Pacific Journal of Clinical Nutrition
JA  - ASIA PAC J CLIN NUTR
VL  - 22
IS  - 3
PB  - Asia Pacific Journal of Clinical Nutrition
AB  - Coronary artery calcification is a recognised risk factor for ischaemic heart disease and mortality. Evidence is now strong that Mönckeberg's arteriosclerosis, a form of vascular calcification, can be attributable to vitamin K deficiency, but that vitamin K-2, especially the MK-4 form from foods like cheese can be protective. Warfarin blocks the recycling of hepatic and peripheral vitamin K leading to secondary vitamin K deficiency with adverse effects on vasculature, bone, kidneys, brain and other tissues and systems (inflammatory, immune function and neoplasia at least). There is individual susceptibility to vitamin K deficiency and warfarin sensitivity, partly explicable in terms of genetic polymorphisms, epigenetics, diet and pharmacotherapy. The emergence of extensive coronary calcification in a man with atrial fibrillation treated for a decade with warfarin is described by way of illustration and to raise the present clinical management conundrums. Finally, a putative set of recommendations is provided.
SN  - 0964-7058
AD  - Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan, Republic of China.
U2  - PMID: 24066371.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109658832
T1  - Clinical decision-making for vitamin K-1 and K-2 deficiency and coronary artery calcification with warfarin therapy: are diet, factor Xa inhibitors or both the answer?
AU  - Wahlqvist, Mark L
AU  - Tanaka, Kiyoshi
AU  - Tzeng, Bing-Hsiean
Y1  - 2013/06//
N1  - Accession Number: 109658832. Language: English. Entry Date: 20140815. Revision Date: 20150923. Publication Type: Journal Article. Journal Subset: Allied Health; Asia; Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed. Special Interest: Nutrition; Public Health. NLM UID: 9440304. 
SP  - 492
EP  - 496
JO  - Asia Pacific Journal of Clinical Nutrition
JF  - Asia Pacific Journal of Clinical Nutrition
JA  - ASIA PAC J CLIN NUTR
VL  - 22
IS  - 2
PB  - Asia Pacific Journal of Clinical Nutrition
AB  - Coronary artery calcification is a recognised risk factor for ischaemic heart disease and mortality. Evidence is now strong that Mönckeberg's arteriosclerosis, a form of vascular calcification, can be attributable to vitamin K deficiency, but that vitamin K-2, especially the MK-4 form from foods like cheese can be protective. Warfarin blocks the recycling of hepatic and peripheral vitamin K leading to secondary vitamin K deficiency with adverse effects on vasculature, bone, kidneys, brain and other tissues and systems (inflammatory, immune function and neoplasia at least). There is individual susceptibility to vitamin K deficiency and warfarin sensitivity, partly explicable in terms of genetic polymorphisms, epigenetics, diet and pharmacotherapy. The emergence of extensive coronary calcification in a man with atrial fibrillation treated for a decade with warfarin is described by way of illustration and to raise the present clinical management conundrums. Finally, a putative set of recommendations is provided.
SN  - 0964-7058
AD  - Department of Cardiology, Tri-Service General Hospital, No 325, Sec 2, Chenggong Rd, Neihu District, Taipei 114, Taiwan, ROC. 894020086@mail.ndmctsgh.edu.tw.
U2  - PMID: 23945401.
DO  - 10.6133/apjcn.2013.22.3.21
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104203917
T1  - Clinical digest. Two servings of oily fish a week provides optimum benefits to cardiac health.
Y1  - 2013/07/24/
N1  - Accession Number: 104203917. Language: English. Entry Date: 20130729. Revision Date: 20150819. Publication Type: Journal Article; brief item; pictorial. Journal Subset: Double Blind Peer Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 9012906. 
KW  - Fish
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Mediterranean Diet
SP  - 16
EP  - 17
JO  - Nursing Standard
JF  - Nursing Standard
JA  - NURS STAND
VL  - 27
IS  - 47
PB  - RCNi
SN  - 0029-6570
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105707648
T1  - Clinical profile and management of hypertensive patients with chronic ischemic heart disease and renal dysfunction attended by cardiologists in daily clinical practice.
AU  - Barrios V
AU  - Escobar C
AU  - Murga N
AU  - de Pablo C
AU  - Bertomeu V
AU  - Calderón A
AU  - Echarri R
Y1  - 2008/11//2008 Nov
N1  - Accession Number: 105707648. Language: English. Entry Date: 20081205. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 8306882. 
KW  - Cardiology -- Methods
KW  - Hypertension -- Physiopathology
KW  - Kidney Failure, Chronic -- Physiopathology
KW  - Myocardial Ischemia -- Physiopathology
KW  - Professional Practice
KW  - Aged
KW  - Creatinine -- Blood
KW  - Female
KW  - Glomerular Filtration Rate
KW  - Hypertension -- Complications
KW  - Hypertension -- Drug Therapy
KW  - Kidney Failure, Chronic -- Complications
KW  - Male
KW  - Middle Age
KW  - Myocardial Ischemia -- Complications
SP  - 2230
EP  - 2235
JO  - Journal of Hypertension
JF  - Journal of Hypertension
JA  - J HYPERTENS
VL  - 26
IS  - 11
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - OBJECTIVE: The present study was designed to assess the influence of renal function on the clinical profile and management of the hypertensive outpatients with chronic ischemic heart disease. METHODS: A total of 112 investigators, all cardiologists, were asked to consecutively enrol outpatients of at least 18 years of age, both sexes, with an established diagnosis of hypertension and chronic ischemic heart disease. Renal function was assessed by serum creatinine levels and estimated glomerular filtration rate using the Modification of Diet in Renal Disease formula. Renal impairment was considered a serum creatinine of at least 1.2/1.3 mg/dl (women/men) or an estimated glomerular filtration rate less than 60 ml/min/1.73 m2. Blood pressure was considered controlled when it was less than 140/90 mmHg and less than 130/80 mmHg in diabetic patients or patients with chronic kidney disease. RESULTS: A total of 2024 patients (66.8+/-10.1 years; 31.7% women) were included. A total of 666 (32.9%) and 498 (24.6%) patients exhibited renal function impairment assessed by estimated glomerular filtration rate and serum creatinine, respectively. The subgroup of patients with renal dysfunction was older, with a higher proportion of women with atrial fibrillation, diabetes, organ damage, associated clinical conditions and a worse blood pressure control. No differences were found in clinical profile when the two subgroups of patients with impaired renal function [serum creatinine >or=1.2/>or=1.3 mg/dl (women/men) vs. estimated glomerular filtration rate <60 ml/min per 1.73 m2] were compared. CONCLUSION: Renal function impairment is frequent in the hypertensive population with coronary artery disease. Patients with renal dysfunction represent a subgroup of very high-risk population with more risk factors and comorbidities and worse blood pressure control. The clinical profiles of hypertensive patients with renal function impairment are similar whether renal dysfunction is detected by high serum creatinine or by low estimated glomerular filtration rate.
SN  - 0263-6352
AD  - Department of Cardiology, Hospital Ramon y Cajal, Madrid, Spain. vbarriosa@meditex.es
U2  - PMID: 18854765.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104636174
T1  - Clinical Update on Nursing Home Medicine: 2011.
AU  - Messinger-Rapport, Barbara J.
AU  - Morley, John E.
AU  - Thomas, David R.
AU  - Gammack, Julie K.
Y1  - 2011/11//
N1  - Accession Number: 104636174. Language: English. Entry Date: 20111206. Revision Date: 20150711. Publication Type: Journal Article; questions and answers; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Gerontologic Care. NLM UID: 100893243. 
KW  - Long Term Care
KW  - Gerontologic Care
KW  - Nursing Homes
KW  - Osteoporosis -- Drug Therapy -- In Old Age
KW  - Diabetes Mellitus -- Therapy -- In Old Age
KW  - Weight Loss -- Therapy -- In Old Age
KW  - Anticoagulants -- Therapeutic Use -- In Old Age
KW  - Proton Pump Inhibitors -- Adverse Effects -- In Old Age
KW  - Delirium -- Prevention and Control -- In Old Age
KW  - Delirium -- Therapy -- In Old Age
KW  - Polypharmacy -- Adverse Effects -- In Old Age
KW  - Geriatrics
KW  - Diphosphonates -- Therapeutic Use
KW  - Diphosphonates -- Administration and Dosage
KW  - Diphosphonates -- Adverse Effects
KW  - Female
KW  - Fractures -- Prevention and Control
KW  - Male
KW  - Diphosphonates -- Pharmacokinetics
KW  - Diphosphonates -- Pharmacodynamics
KW  - Vitamin D -- Administration and Dosage
KW  - Dietary Supplementation
KW  - Estrogens -- Therapeutic Use
KW  - Bone Density -- Evaluation
KW  - Risk Assessment
KW  - Geriatric Assessment
KW  - Glycemic Control
KW  - Blood Glucose Monitoring
KW  - Exercise
KW  - Hypoglycemic Agents -- Therapeutic Use
KW  - Diabetes Mellitus -- Drug Therapy
KW  - Hypoglycemic Agents -- Pharmacodynamics
KW  - Hypoglycemic Agents -- Adverse Effects
KW  - Hypoglycemic Agents -- Administration and Dosage
KW  - Hypoglycemic Agents -- Pharmacokinetics
KW  - Multidisciplinary Care Team
KW  - Hemoglobin A, Glycosylated -- Analysis
KW  - Diabetic Diet
KW  - Weight Loss -- Etiology
KW  - Appetite Stimulating Agents -- Therapeutic Use
KW  - Warfarin -- Therapeutic Use
KW  - Stroke -- Prevention and Control
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Warfarin -- Adverse Effects
KW  - Treatment Duration
KW  - Stents
KW  - Clopidogrel Bisulfate -- Therapeutic Use
KW  - Clopidogrel Bisulfate -- Administration and Dosage
KW  - Clopidogrel Bisulfate -- Adverse Effects
KW  - Proton Pump Inhibitors -- Therapeutic Use
KW  - Gastroesophageal Reflux -- Drug Therapy
KW  - Drug Interactions
KW  - Delirium -- Diagnosis
KW  - Delirium -- Risk Factors
KW  - Clinical Assessment Tools
KW  - Mental Status -- Evaluation
KW  - Delirium -- Drug Therapy
KW  - Antipsychotic Agents -- Therapeutic Use
KW  - Inpatients
KW  - Aged
SP  - 615
EP  - 626.e6
JO  - Journal of the American Medical Directors Association
JF  - Journal of the American Medical Directors Association
JA  - J AM MED DIR ASSOC
VL  - 12
IS  - 9
CY  - New York, New York
PB  - Elsevier Science
AB  - This represents the fifth article in the series on yearly updates of hot topics in long term care
SN  - 1525-8610
AD  - Cleveland Clinic, Section of Geriatric Medicine, Cleveland, OH
AD  - Division of Geriatric Medicine, Saint Louis University School of Medicine, St. Louis, MO
U2  - PMID: 22018015.
DO  - 10.1016/j.jamda.2011.08.007
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107914867
T1  - Coffee and tea: perks for health and longevity?
AU  - Bhatti, Salman K
AU  - O'Keefe, James H
AU  - Lavie, Carl J
Y1  - 2013/11//
N1  - Accession Number: 107914867. Language: English. Entry Date: 20140606. Revision Date: 20150712. Publication Type: Journal Article. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Nutrition. NLM UID: 9804399. 
KW  - Coffee
KW  - Longevity -- Drug Effects
KW  - Polyphenols -- Pharmacodynamics
KW  - Tea
KW  - Antioxidants -- Pharmacodynamics
KW  - Anxiety -- Etiology
KW  - Anxiety -- Physiopathology
KW  - Blood Glucose -- Metabolism
KW  - Blood Pressure -- Drug Effects
KW  - Caffeine -- Pharmacodynamics
KW  - Calcium -- Blood
KW  - Cardiovascular Diseases -- Prevention and Control
KW  - Clinical Trials
KW  - Coffee -- Adverse Effects
KW  - Diabetes Mellitus -- Prevention and Control
KW  - Dose-Response Relationship, Drug
KW  - Fractures -- Etiology
KW  - Fractures -- Physiopathology
KW  - Insomnia -- Etiology
KW  - Insomnia -- Physiopathology
KW  - Neoplasms -- Prevention and Control
KW  - Nonexperimental Studies
KW  - Obesity -- Prevention and Control
KW  - Risk Factors
KW  - Tea -- Adverse Effects
SP  - 688
EP  - 697
JO  - Current Opinion in Clinical Nutrition & Metabolic Care
JF  - Current Opinion in Clinical Nutrition & Metabolic Care
JA  - CURR OPIN CLIN NUTR METABOLIC CARE
VL  - 16
IS  - 6
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - PURPOSE OF REVIEW: Tea and coffee, after water, are the most commonly consumed beverages in the world and are the top sources of caffeine and antioxidant polyphenols in the American diet. The purpose of this review is to assess the health effects of chronic tea and/or coffee consumption. RECENT FINDINGS: Tea consumption, especially green tea, is associated with significantly reduced risks for stroke, diabetes and depression, and improved levels of glucose, cholesterol, abdominal obesity and blood pressure. Habitual coffee consumption in large epidemiological studies is associated with reduced mortality, both for all-cause and cardiovascular deaths. In addition, coffee intake is associated with risks of heart failure, stroke, diabetes mellitus and some cancers in an inverse dose-dependent fashion. Surprisingly, coffee is associated with neutral to reduced risks for both atrial and ventricular arrhythmias. However, caffeine at high doses can increase anxiety, insomnia, calcium loss and possibly the risk of fractures. SUMMARY: Coffee and tea can generally be recommended as health-promoting additions to an adult diet. Adequate dietary calcium intake may be particularly important for tea and coffee drinkers.
SN  - 1363-1950
AD  - aSaint Luke's Mid America Heart Institute & University of Missouri-Kansas City, Kansas City, Missouri bJohn Ochsner Heart and Vascular Institute, Ochsner Clinical School, The University of Queensland School of Medicine, New Orleans cDepartment of Preventive Medicine, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, USA.
U2  - PMID: 24071782.
DO  - 10.1097/MCO.0b013e328365b9a0
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105981964
T1  - Combination sedoanalgesia with remifentanil and propofol versus remifentanil and midazolam for elective cardioversion after coronary artery bypass grafting.
AU  - Yildirim V
AU  - Doganci S
AU  - Bolcal C
AU  - Oz BS
AU  - Kucukarslan N
AU  - Cosar A
AU  - Guzeldemir ME
Y1  - 2007/05//
N1  - Accession Number: 105981964. Language: English. Entry Date: 20080215. Revision Date: 20150711. Publication Type: Journal Article; clinical trial; research. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 8611864. 
KW  - Anesthetics, Intravenous -- Administration and Dosage
KW  - Atrial Fibrillation -- Therapy
KW  - Cardioversion
KW  - Coronary Artery Bypass -- Adverse Effects
KW  - Midazolam -- Therapeutic Use
KW  - Piperidines -- Administration and Dosage
KW  - Propofol -- Therapeutic Use
KW  - Anesthesia Recovery
KW  - Anesthetics, Intravenous -- Adverse Effects
KW  - Atrial Fibrillation -- Etiology
KW  - Drug Combinations
KW  - Female
KW  - Male
KW  - Midazolam -- Administration and Dosage
KW  - Midazolam -- Adverse Effects
KW  - Middle Age
KW  - Patient Satisfaction
KW  - Piperidines -- Adverse Effects
KW  - Propofol -- Administration and Dosage
KW  - Propofol -- Adverse Effects
KW  - Prospective Studies
KW  - Single-Blind Studies
KW  - Human
SP  - 662
EP  - 670
JO  - Advances in Therapy
JF  - Advances in Therapy
JA  - ADV THER
VL  - 24
IS  - 3
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
AB  - Postoperative atrial fibrillation (AF) occurs in up to 50% of cardiac surgery patients and represents the most common postoperative arrhythmic complication. Elective cardioversion, a short but painful procedure, remains an option for patients who do not convert to sinus rhythm with medical therapy. Combinations of remifentanil (a potent analgesic with a short elimination time) with propofol (a hypnotic agent) or midazolam (a sedative agent) produce a synergistic interaction. This study was undertaken to compare these combinations in terms of effectiveness and pain relief when given as sedoanalgesia for elective cardioversion. In this prospective, randomized trial, 60 adult patients with postoperative AF after coronary artery bypass grafting were given a single dose of propofol 1 mg/kg combined with remifentanil 0.1 microg/kg (group 1), or midazolam 0.05 mg/kg combined with remifentanil 0.1 microg/kg (group 2). Cardiorespiratory parameters were monitored and recorded. Demographic data were similar (P>.05) and sufficient sedoanalgesia and successful cardioversion were achieved in both groups. Hemodynamic parameters revealed no significant differences between groups (P>.05); however, induction time, time to eye opening, recuperation time, and time to full recovery of psychomotor function were faster in group 1 than in group 2 (P<.05). The remifentanil/propofol combination provided sufficient analgesia, satisfactory hemodynamic stability, and mild respiratory depression, along with faster recovery and discharge times from the intensive care unit.
SN  - 0741-238X
U2  - PMID: 17660177.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108172410
T1  - Co-morbid cardio-respiratory disease: management dilemmas.
Y1  - 2012/03/23/
N1  - Accession Number: 108172410. Language: English. Entry Date: 20120330. Revision Date: 20150712. Publication Type: Journal Article; case study; pictorial. Journal Subset: Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. Special Interest: Advanced Nursing Practice. NLM UID: 9432228. 
KW  - Comorbidity
KW  - Ventricular Dysfunction, Left
KW  - Atrial Fibrillation
KW  - Diabetes Mellitus, Type 2
KW  - Heart Failure
KW  - Pulmonary Disease, Chronic Obstructive
KW  - Life Style
KW  - Education, Continuing (Credit)
KW  - Alcohol Drinking
KW  - Diet
KW  - Physical Activity
KW  - Patient History Taking
KW  - Advanced Nursing Practice
KW  - Heart Failure -- Drug Therapy
KW  - Angiotensin-Converting Enzyme Inhibitors -- Therapeutic Use
KW  - Adrenergic Beta-Antagonists -- Therapeutic Use
KW  - Calcium Channel Blockers -- Therapeutic Use
KW  - Metformin -- Therapeutic Use
KW  - Pioglitazone -- Therapeutic Use
KW  - Disease Exacerbation
KW  - Information Resources
KW  - World Wide Web
KW  - Warfarin -- Therapeutic Use
KW  - Stroke -- Prevention and Control
KW  - Psychosocial Aspects of Illness
KW  - Self Assessment
KW  - Office Nursing
SP  - 35
EP  - 39
JO  - Practice Nurse
JF  - Practice Nurse
JA  - PRACT NURSE
VL  - 42
IS  - 5
PB  - Medical Education Solutions Ltd
SN  - 0953-6612
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108172410&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106039001
T1  - Comparison of the effects of av nodal ablation versus av nodal modification in patients with congestive heart failure and uncontrolled atrial fibrillation.
AU  - Twidale N
AU  - Mcdonald T
AU  - Nave K
AU  - Seal A
Y1  - 1998/04//
N1  - Accession Number: 106039001. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Allied Health; Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7803944. 
SP  - 641
EP  - 651
JO  - Pacing & Clinical Electrophysiology
JF  - Pacing & Clinical Electrophysiology
JA  - PACING CLIN ELECTROPHYSIOL
VL  - 21
IS  - 4P1
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Radiofrequency (RF) catheter ablation of the atrioventricular node (AVN) and implantation of a ventricular pacemaker can improve cardiac performance in patients with congestive heart failure (CHF) and uncontrolled atrial fibrillation (AF). Alternatively, RF catheter modification of the AVN has been proposed to slow ventricular response during AF without requirement for permanent pacing. Among 44 consecutive patients (mean age 69.7 ± 10.2 years) with drug resistant chronic AF, 22 (group I) had AVN ablation with permanent ventricular pacemaker implantation, while 22 patients had attempted AVN modification. Complete AV block was obtained in all group I patients while only seven (32%) AVN modification patients (group II) had permanent slowing of ventricular rate. Among patients in group I, mean left ventricular ejection fraction (EF) increased from 32.2% ± 8.8% before ablation to 41.9% ± 14.6% 4-weeks postablation (P < 0.01); exercise tolerance time (ETT) increased from 2.9 ± 2.2 minutes to 4.5 ± 2.9 minutes (P < 0.01); and quality-of-life score decreased from 66.1 ± 22.6 to 36.9 ± 17.1 (P < 0.01). By comparison, there was only a small increase in ETT in the seven successful group II patients (2.4 ± 1.8 minutes to 3.0 ± 1.9 minutes; P < 0.05) and there was no significant change in EF or quality-of-life. While AVN ablation can occasionally have transient adverse effects, it is more effective than AVN modification for improving cardiac performance in selected patients with CHF and AF.
SN  - 0147-8389
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104244065
T1  - Comparison of ThermoCool® Surround Flow Catheter Versus ThermoCool® Catheter in Achieving Persistent Electrical Isolation of Pulmonary Veins: A Pilot Study.
AU  - Bertaglia, Emanuele
AU  - Fassini, Gaetano
AU  - Anselmino, Matteo
AU  - Stabile, Giuseppe
AU  - Grandinetti, Giuseppe
AU  - Simone, Antonio De
AU  - CalÒ, Leonardo
AU  - Pandozi, Claudio
AU  - Pratola, Claudio
AU  - Zoppo, Franco
AU  - Tondo, Claudio
AU  - Iuliano, Assunta
AU  - Gaita, Fiorenzo
Y1  - 2013/03//
N1  - Accession Number: 104244065. Language: English. Entry Date: 20130312. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts; randomized controlled trial. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9010756. 
KW  - Pulmonary Veins -- Surgery
KW  - Atrial Fibrillation -- Therapy
KW  - Catheter Ablation -- Methods
KW  - Human
KW  - Randomized Controlled Trials
KW  - Multicenter Studies
KW  - Descriptive Statistics
KW  - Pilot Studies
KW  - Recurrence
KW  - Treatment Outcomes
KW  - Italy
KW  - Middle Age
KW  - Aged
KW  - Male
KW  - Female
KW  - Chi Square Test
KW  - Unpaired T-Tests
KW  - Data Analysis Software
SP  - 269
EP  - 273
JO  - Journal of Cardiovascular Electrophysiology
JF  - Journal of Cardiovascular Electrophysiology
JA  - J CARDIOVASC ELECTROPHYSIOL
VL  - 24
IS  - 3
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Persistent Electrical Isolation of Pulmonary Veins. Introduction: Aim of this study was to compare efficacy and safety of the new ThermoCool Surround Flow® catheter (SFc) versus the ThermoCool® (TCc) in achieving persistent circumferential electrical isolation of the pulmonary veins (PVs) in patients with paroxysmal atrial fibrillation (AF). Methods and Results: This multicenter, randomized, controlled study enrolled patients suffering from paroxysmal AF. Randomization was run in a one-to-one fashion between radiofrequency ablation by TCc or SFc. Aim of PVs ablation was documentation of electrical isolation with exit/entrance block recorded on a circular catheter. Among the 106 enrolled patients, 52 (49.0%) were randomized to TCc and 54 (51.0%) to SFc. Total volume of infused saline solution during the procedure was lower in the SFc than in TCc group (752.7 ± 268.6 mL vs 1,165.9 ± 436.2 mL, P < 0.0001). Number of identified and isolated PVs was similar in the 2 groups. Number of PVs remaining isolated 30 minutes after ablation was higher in the SFc than in TCc group (95.2% vs 90.5%, P < 0.03), mainly driven by acute ablation result in the left PVs (96.1% vs 89.7%, P < 0.04). Complications were seldom and observed only in the TCc group (0% vs 3.84%, P < 0.03). At 6-month follow-up SFc patients reported a trend toward less AF recurrences compared to those in the TCc group (22.9% vs 27.0%, P = 0.69). Conclusion: PV isolation by SFc lowered the rate of left PV early reconnections and reduced the volume of infused saline solution while maintaining the safety profile of AF ablation. (J Cardiovasc Electrophysiol, Vol. 24, pp. 269-273, March 2013)
SN  - 1045-3873
AD  - Civic Hospital, Mirano-Venice
AD  - Monzino Cardiology Center, Milan
AD  - Department of Medical Sciences, University of Turin
AD  - Mediterranean Clinic, Naples
AD  - University of Bari
AD  - San Michele Clinic, Maddaloni-Caserta
AD  - Casilino Clinic, Rome
AD  - San Filippo Neri Hospital, Rome
AD  - Sant'Anna Hospital, University of Ferrara; Italy
DO  - 10.1111/jce.12031
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108222708
T1  - Connexin43 mutation causes heterogeneous gap junction loss and sudden infant death.
AU  - Van Norstrand DW
AU  - Asimaki A
AU  - Rubinos C
AU  - Dolmatova E
AU  - Srinivas M
AU  - Tester DJ
AU  - Saffitz JE
AU  - Duffy HS
AU  - Ackerman MJ
Y1  - 2012/01/24/
N1  - Accession Number: 108222708. Language: English. Entry Date: 20120330. Revision Date: 20150712. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0147763. 
KW  - Membrane Proteins
KW  - Cell Membrane -- Pathology
KW  - Cell Membrane -- Physiology
KW  - Mutation
KW  - Sudden Infant Death
KW  - Sudden Infant Death -- Pathology
KW  - Adult
KW  - Animals
KW  - Glycoproteins -- Metabolism
KW  - Prospective Studies
KW  - Membrane Proteins -- Metabolism
KW  - Cytoskeletal Proteins -- Metabolism
KW  - Female
KW  - Disease Susceptibility
KW  - Human
KW  - Infant
KW  - Male
KW  - Cells -- Pathology
KW  - Cell Physiology
KW  - Cytological Techniques
KW  - Biological Transport
KW  - Rats
SP  - 474
EP  - 481
JO  - Circulation
JF  - Circulation
JA  - CIRCULATION
VL  - 125
IS  - 3
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - BACKGROUND: An estimated 10% to 15% of sudden infant death syndrome (SIDS) cases may stem from channelopathy-mediated lethal arrhythmias. Loss of the GJA1-encoded gap junction channel protein connexin43 is known to underlie formation of lethal arrhythmias. GJA1 mutations have been associated with cardiac diseases, including atrial fibrillation. Therefore, GJA1 is a plausible candidate gene for premature sudden death. METHODS AND RESULTS: GJA1 open reading frame mutational analysis was performed with polymerase chain reaction, denaturing high-performance liquid chromatography, and direct DNA sequencing on DNA from 292 SIDS cases. Immunofluorescence and dual whole-cell patch-clamp studies were performed to determine the functionality of mutant gap junctions. Immunostaining for gap junction proteins was performed on SIDS-associated paraffin-embedded cardiac tissue. Two rare, novel missense mutations, E42K and S272P, were detected in 2 of 292 SIDS cases, a 2-month-old white boy and a 3-month-old white girl, respectively. Analysis of the E42K victim's parental DNA demonstrated a de novo mutation. Both mutations involved highly conserved residues and were absent in >1000 ethnically matched reference alleles. Immunofluorescence demonstrated no trafficking abnormalities for either mutation, and S272P demonstrated wild-type junctional conductance. However, junctional conductance measurements for the E42K mutation demonstrated a loss of function not rescued by wild type. Moreover, the E42K victim's cardiac tissue demonstrated a mosaic immunostaining pattern for connexin43 protein. CONCLUSIONS: This study provides the first molecular and functional evidence implicating a GJA1 mutation as a novel pathogenic substrate for SIDS. E42K-connexin43 demonstrated a trafficking-independent reduction in junctional coupling in vitro and a mosaic pattern of mutational DNA distribution in deceased cardiac tissue, suggesting a novel mechanism of connexin43-associated sudden death.
SN  - 0009-7322
AD  - Mayo Clinic, Windland Smith Rice Sudden Death Genomics Laboratory, Guggenheim 501, Rochester, MN 55905. ackerman.michael@mayo.edu.
U2  - PMID: 22179534.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108222708&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 112753706
T1  - Consumption of Caffeinated Products and Cardiac Ectopy.
AU  - Dixit, Shalini
AU  - Stein, Phyllis K.
AU  - Dewland, Thomas A.
AU  - Dukes, Jonathan W.
AU  - Vittinghoff, Eric
AU  - Heckbert, Susan R.
AU  - Marcus, Gregory M.
Y1  - 2016/01//
N1  - Accession Number: 112753706. Language: English. Entry Date: In Process. Revision Date: 20160527. Publication Type: journal article. Journal Subset: Biomedical; Europe; UK & Ireland. Grant Information: N01HC85080/HC/NHLBI NIH HHS/United States. NLM UID: 101580524. 
SP  - 1
EP  - 10
JO  - Journal of the American Heart Association
JF  - Journal of the American Heart Association
JA  - J AM HEART ASSOC
VL  - 5
IS  - 1
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Background: Premature cardiac contractions are associated with increased morbidity and mortality. Though experts associate premature atrial contractions (PACs) and premature ventricular contractions (PVCs) with caffeine, there are no data to support this relationship in the general population. As certain caffeinated products may have cardiovascular benefits, recommendations against them may be detrimental.Methods and Results: We studied Cardiovascular Health Study participants with a baseline food frequency assessment, 24-hour ambulatory electrocardiography (Holter) monitoring, and without persistent atrial fibrillation. Frequencies of habitual coffee, tea, and chocolate consumption were assessed using a picture-sort food frequency survey. The main outcomes were PACs/h and PVCs/hour. Among 1388 participants (46% male, mean age 72 years), 840 (61%) consumed ≥1 caffeinated product per day. The median numbers of PACs and PVCs/h and interquartile ranges were 3 (1-12) and 1 (0-7), respectively. There were no differences in the number of PACs or PVCs/h across levels of coffee, tea, and chocolate consumption. After adjustment for potential confounders, more frequent consumption of these products was not associated with ectopy. In examining combined dietary intake of coffee, tea, and chocolate as a continuous measure, no relationships were observed after multivariable adjustment: 0.48% fewer PACs/h (95% CI -4.60 to 3.64) and 2.87% fewer PVCs/h (95% CI -8.18 to 2.43) per 1-serving/week increase in consumption.Conclusions: In the largest study to evaluate dietary patterns and quantify cardiac ectopy using 24-hour Holter monitoring, we found no relationship between chronic consumption of caffeinated products and ectopy.
SN  - 2047-9980
AD  - University of California, San Francisco, San Francisco, CA
AD  - Washington University School of Medicine, St. Louis, MO
AD  - Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR
AD  - University of Washington and Group Health Research Institute, Seattle, WA
U2  - PMID: 26813889.
DO  - 10.1161/JAHA.115.002503
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104895563
T1  - Contributions of a Hemodynamic Sensor Embedded in an Atrial Lead in a Porcine Model.
AU  - Bordachar, Pierre
AU  - Garrigue, Stephane
AU  - Ritter, Philippe
AU  - Ploux, Sylvain
AU  - Labrousse, Louis
AU  - Casset, Cyril
AU  - Haissaguerre, Michel
AU  - Dos Santos, Pierre
Y1  - 2011/05//
N1  - Accession Number: 104895563. Language: English. Entry Date: 20110526. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts; tracings. Commentary: Sweeney Michael O. Peak Endocardial Acceleration Signals for Atrial Mechanical Activation. (J CARDIOVASC ELECTROPHYSIOL) May2011; 22 (5): 584-586. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9010756. 
KW  - Electrodes, Implanted
KW  - Heart Atrium, Right
KW  - Hemodynamics -- Evaluation
KW  - Cardiac Pacing, Artificial
KW  - Animal Studies
KW  - Swine
KW  - Muscle Contraction
KW  - Dobutamine -- Administration and Dosage
KW  - Descriptive Statistics
KW  - Pearson's Correlation Coefficient
KW  - Esmolol -- Administration and Dosage
KW  - Monitoring, Physiologic -- Methods
SP  - 579
EP  - 583
JO  - Journal of Cardiovascular Electrophysiology
JF  - Journal of Cardiovascular Electrophysiology
JA  - J CARDIOVASC ELECTROPHYSIOL
VL  - 22
IS  - 5
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - . Introduction: Preliminary studies have revealed a high correlation between peak endocardial acceleration (PEA) measured with a sensor embedded in a ventricular lead and human cardiac contractility. In this study we assessed (1) the contributions made by measurements of PEA1, an index of ventricular systolic contraction, from the right atrium, and (2) the feasibility of recording a fourth component of PEA (PEA4), coincident with atrial contraction and corresponding to the phonocardiographic fourth heart sound. Methods: We placed a PEA sensor embedded at the tip of a right atrial lead in 9 pigs. A 7F Millar catheter tip micromanometer was introduced into the left ventricular (LV) cavity to measure dP/dt. Myocardial contractility was increased by infusion of dobutamine and depressed by the infusion of esmolol. We searched, during VDD pacing, for PEA4 following atrial systole, while gradually lengthening the atrioventricular delay. Ventricular fibrillation was then triggered by rapid stimulation. Results: The changes in PEA1 were correlated with the changes in LV dP/dt (r = 0.91; P < 0.001). A low-frequency component of the endocardial signal (PEA4) was visible approximately 50 milliseconds after the atrial electrogram in all experiments. Following the induction of ventricular fibrillation, PEA4 remained visible on the endocardial recording, simultaneous with the sensed atrial electrogram. Conclusions: This study confirms the merit of embedding a PEA sensor in an atrial lead. The exploitation of the information provided by the PEA1 signal remains pertinent and the possibility to record an additional PEA4 component offers the perspective of new clinical applications. (J Cardiovasc Electrophysiol, Vol. 22, pp. 579-583 May 2011)
SN  - 1045-3873
AD  - Bordeaux University 2, Bordeaux; University Hospital of Bordeaux, Bordeaux
AD  - Clinique Saint-Augustin, Bordeaux
AD  - Sorin Biomedica, France
U2  - PMID: 20946232.
DO  - 10.1111/j.1540-8167.2010.01930.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104814850
T1  - Dabigatran: A new orally available anticoagulant for prevention of strokes and thrombosis in patients with atrial fibrillation.
AU  - Talati, Ripple
AU  - White, C. Michael
Y1  - 2011/02//
N1  - Accession Number: 104814850. Language: English. Entry Date: 20110224. Revision Date: 20150711. Publication Type: Journal Article; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9513311. 
KW  - Atrial Fibrillation -- Complications
KW  - Thrombin -- Antagonists and Inhibitors
KW  - Stroke -- Prevention and Control
KW  - Thrombosis -- Prevention and Control
KW  - Anticoagulants -- Therapeutic Use
KW  - Anticoagulants -- Adverse Effects
KW  - Anticoagulants -- Pharmacodynamics
KW  - Anticoagulants -- Pharmacokinetics
KW  - Clinical Trials
KW  - Treatment Outcomes
KW  - Drug Interactions
KW  - Anticoagulants -- Administration and Dosage
KW  - Drug Administration Schedule
KW  - Anticoagulants -- Contraindications
KW  - Anticoagulants -- Economics
KW  - Formularies -- Evaluation
SP  - 44
EP  - 53
JO  - Formulary
JF  - Formulary
JA  - FORMULARY
VL  - 46
IS  - 2
CY  - North Olmsted, Ohio
PB  - Advanstar Communications Inc.
AB  - Atrial fibrillation (AF) is the most common clinically significant cardiac arrhythmia in the United States and increases the risk of stroke 4.5-fold. Stroke can result in substantial morbidity, mortality, decreased quality of life, and related healthcare costs. Vitamin K antagonists such as warfarin are effective for stroke prevention in AF, but have several drawbacks. There is a need for new anticoagulant agents that are effective, safe, and convenient to use. Dabigatran etexilate (Pradaxa) is an orally administered reversible direct thrombin inhibitor approved by FDA on October 19,2010, for the prevention of stroke and thrombosis in patients with AF. In clinical studies, it was given orally by fixed once- or twice-daily dosing, does not require dietary adjustments or routine laboratory monitoring, and is not expected to have cytochrome P450- dependent drug interactions, although it does have P-glycoprotein interactions. In the RE-LY trial, in patients with AF and at least 1 other risk factor for stroke (average CHADS2 score 2.1), dabigatran etexilate 150 mg twice daily was superior to warfarin at preventing the combination of stroke and systemic embolie events with a similar rate of major bleeding.
SN  - 1082-801X
AD  - Senior scientist, Hartford Hospital, Hartford, Conn.; University of Connecticut, Storrs
AD  - Professor of pharmacy, University of Connecticut, Storrs; Director, UCONN/Hartford Hospital, Evidence-based Practice Center, Hartford, Conn.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104475709
T1  - Dabigatran: an oral direct thrombin inhibitor for use in atrial fibrillation.
AU  - Bendel, Stephen D
AU  - Bona, Robert
AU  - Baker, William L
Y1  - 2011/06//
N1  - Accession Number: 104475709. Language: English. Entry Date: 20120914. Revision Date: 20150711. Publication Type: Journal Article; review; tables/charts. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Critical Care. NLM UID: 8611864. 
KW  - Anticoagulants -- Administration and Dosage
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Dabigatran Etexilate -- Pharmacodynamics
KW  - Dabigatran Etexilate -- Pharmacokinetics
KW  - Stroke -- Prevention and Control
KW  - Atrial Fibrillation -- Epidemiology
KW  - Cerebral Ischemia, Transient -- Prevention and Control
KW  - Clinical Trials
KW  - Costs and Cost Analysis
KW  - Dabigatran Etexilate -- Adverse Effects
KW  - Equipment and Supplies
KW  - Thrombin -- Antagonists and Inhibitors
SP  - 460
EP  - 472
JO  - Advances in Therapy
JF  - Advances in Therapy
JA  - ADV THER
VL  - 28
IS  - 6
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
AB  - Atrial fibrillation (AF) is well known as one of the leading causes of stroke and systemic embolism. Anticoagulation therapy is recommended in all patients at moderate-to-high risk of stroke. The vitamin K antagonist warfarin has traditionally been used in these patients but presents challenges in dosing and monitoring in these patients. The oral direct thrombin inhibitor dabigatran etexilate (Pradaxa(R); Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA) was recently approved for use in the US for preventing stroke and systemic embolism in patients with nonvalvular AF. Clinical trials have shown it to reduce the risk of stroke and systemic embolism when compared with warfarin (goal international normalized ratio [INR] 2-3) with a similar risk for severe bleeding. It can be given twice daily, with the dose adjusted for renal function. It does not have any dietary restrictions, has few drug interactions (except involving permeability [P]-glycoprotein [P-gp] agents), and does not require routine laboratory monitoring. Patients may experience significant dyspepsia with its use. Compared with warfarin there is increased risk for gastrointestinal bleeding and perhaps myocardial infarction. Currently, no reversal agent exists for use in situations of overdose or severe bleeding although some strategies have been suggested. Despite its high acquisition cost compared with warfarin, analysis using theoretical models has shown it to be cost-effective. Dabigatran offers a unique alternative to warfarin in patients with nonvalvular AF and can be beneficial in patients requiring anticoagulation therapy.
SN  - 0741-238X
AD  - Schools of Pharmacy and Medicine, Storrs and Farmington CT & Department of Hematology-Oncology, University of Connecticut, Farmington, USA.
U2  - PMID: 21533567.
DO  - 10.1007/s12325-011-0025-1
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106401278
T1  - Decreasing your risk of abnormal heart rhythm.
Y1  - 2005/11//
N1  - Accession Number: 106401278. Language: English. Entry Date: 20060224. Revision Date: 20150711. Publication Type: Journal Article; brief item. Journal Subset: Consumer Health; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 8507508. 
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Weight Control
SP  - 4
EP  - 4
JO  - Mayo Clinic Health Letter
JF  - Mayo Clinic Health Letter
JA  - MAYO CLIN HEALTH LETT
VL  - 23
IS  - 11
CY  - Rochester, Minnesota
PB  - Mayo Foundation for Medical Education & Research
SN  - 0741-6245
U2  - PMID: 16419294.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 115595389
T1  - Design and Rationale of the RELAXED (Recurrent Embolism Lessened by rivaroxaban, an Anti-Xa agent, of Early Dosing for acute ischemic stroke and transient ischemic attack with atrial fibrillation) Study.
AU  - Yasaka, Masahiro
AU  - Minematsu, Kazuo
AU  - Toyoda, Kazunori
AU  - Yamagami, Hiroshi
AU  - Yoshimura, Shinichi
AU  - Nagao, Takehiko
AU  - Mori, Etsuro
AU  - Hirano, Teruyuki
AU  - Hamasaki, Toshimitsu
AU  - Yamaguchi, Takenori
Y1  - 2016/06//
N1  - Accession Number: 115595389. Language: English. Entry Date: In Process. Revision Date: 20160530. Publication Type: journal article. Journal Subset: Biomedical; Double Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9111633. 
SP  - 1342
EP  - 1348
JO  - Journal of Stroke & Cerebrovascular Diseases
JF  - Journal of Stroke & Cerebrovascular Diseases
JA  - J STROKE CEREBROVASC DIS
VL  - 25
IS  - 6
CY  - Philadelphia, Pennsylvania
PB  - W B Saunders
AB  - Background: In the acute phase of cardioembolic stroke in patients with nonvalvular atrial fibrillation (NVAF), the recurrence rate is high. Nonvitamin K antagonist oral anticoagulants may be appropriate for prevention of early recurrence because they have a much lower risk of hemorrhagic stroke than warfarin.Methods: RELAXED (Recurrent Embolism Lessened by rivaroxaban, an Anti-Xa agent, of Early Dosing for acute ischemic stroke and transient ischemic attack with atrial fibrillation) study is an observational study designed to investigate the optimal timing to start administration of rivaroxaban for prevention of recurrence in NVAF patients in the acute phase of cardioembolic stroke (ClinicalTrials.gov: NCT02129920 and UMIN-clinical trials registry: UMIN000013932). It will evaluate the efficacy and safety of rivaroxaban with regard to infarct size, timing of initiation of rivaroxaban medication, and other patient characteristics. A total of 2000 consecutive patients with acute ischemic stroke in the territory of the middle cerebral artery and NVAF will be enrolled in 100 institutes throughout Japan, and they will receive rivaroxaban within 30 days of the index stroke for secondary prevention of stroke. The infarct size within 48 hours after stroke onset will be measured by diffusion-weighted magnetic resonance imaging. The primary efficacy endpoint is recurrent ischemic stroke, and the primary safety endpoint is major bleeding during the observational period of 3 months after stroke onset. The optimal timing to start treatment with rivaroxaban during the acute stage of ischemic stroke will be determined by analysis of the correlation between primary endpoints and the size of cerebral infarct.Conclusions: The RELAXED observational registry study will elucidate the optimal timing of the initiation of rivaroxaban in acute cardioembolic stroke associated with NVAF.
SN  - 1052-3057
AD  - Department of Cerebrovascular Medicine and Neurology, Clinical Research Institute, National Hospital Organization, Kyushu Medical Center, Fukuoka, Japan
AD  - Japan Cardiovascular Research Foundation, Suita, Japan
AD  - Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan
AD  - Department of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan
AD  - Department of Neurosurgery, Hyogo College of Medicine, Hyogo, Japan
AD  - Department of Neurology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan
AD  - Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate, School of Medicine, Sendai, Japan
AD  - Department of Stroke and Cerebrovascular Medicine, Kyorin University, Tokyo, Japan
AD  - Department of Advanced Medical Technology Development, National Cerebral and Cardiovascular Center, Suita, Japan
U2  - PMID: 26987488.
DO  - 10.1016/j.jstrokecerebrovasdis.2016.01.035
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 111242094
T1  - Development of a shared decision-making tool to assist patients and clinicians with decisions on oral anticoagulant treatment for atrial fibrillation.
AU  - Kaiser, Karen
AU  - Cheng, Wendy Y.
AU  - Jensen, Sally
AU  - Clayman, Marla L.
AU  - Thappa, Andrew
AU  - Schwiep, Frances
AU  - Chawla, Anita
AU  - Goldberger, Jeffrey J.
AU  - Col, Nananda
AU  - Schein, Jeff
Y1  - 2015/12//
N1  - Accession Number: 111242094. Language: English. Entry Date: 20160713. Revision Date: 20160713. Publication Type: journal article. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Instrumentation: Clinical Decision Making in Nursing Scale (CDMNS) (Jenkins). NLM UID: 0351014. 
KW  - Anticoagulants -- Therapeutic Use
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Decision Making
KW  - Warfarin -- Therapeutic Use
KW  - Risk Factors
KW  - Hemorrhage -- Chemically Induced
KW  - Aged
KW  - Male
KW  - Risk Assessment
KW  - Decision Support Techniques
KW  - Middle Age
KW  - Stroke -- Prevention and Control
KW  - Administration, Oral
KW  - Female
KW  - Aged, 80 and Over
KW  - Scales
SP  - 2261
EP  - 2272
JO  - Current Medical Research & Opinion
JF  - Current Medical Research & Opinion
JA  - CURR MED RES OPIN
VL  - 31
IS  - 12
CY  - Philadelphia, Pennsylvania
PB  - Taylor & Francis Ltd
AB  - Objective: Decision aids (DAs) are increasingly used to operationalize shared decision-making (SDM) but their development is not often described. Decisions about oral anticoagulants (OACs) for atrial fibrillation (AF) involve a trade-off between lowering stroke risk and increasing OAC-associated bleeding risk, and consideration of how treatment affects lifestyle. The benefits and risks of OACs hinge upon a patient's risk factors for stroke and bleeding and how they value these outcomes. We present the development of a DA about AF that estimates patients' risks for stroke and bleeding and assesses their preferences for outcomes.Research Design and Methods: Based on a literature review and expert discussions, we identified stroke and major bleeding risk prediction models and embedded them into risk assessment modules. We identified the most important factors in choosing OAC treatment (warfarin used as the default reference OAC) through focus group discussions with AF patients who had used warfarin and clinician interviews. We then designed preference assessment and introductory modules accordingly. We integrated these modules into a prototype AF SDM tool and evaluated its usability through interviews.Results: Our tool included four modules: (1) introduction to AF and OAC treatment risks and benefits; (2) stroke risk assessment; (3) bleeding risk assessment; and (4) preference assessment. Interactive risk calculators estimated patient-specific stroke and bleeding risks; graphics were developed to communicate these risks. After cognitive interviews, the content was improved. The final AF tool calculates patient-specific risks and benefits of OAC treatment and couples these estimates with patient preferences to improve clinical decision-making.Conclusions: The AF SDM tool may help patients choose whether OAC treatment is best for them and represents a patient-centered, integrative approach to educate patients on the benefits and risks of OAC treatment. Future research is needed to evaluate this tool in a real-world setting. The development process presented can be applied to similar SDM tools.
SN  - 0300-7995
AD  - Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
AD  - Analysis Group Inc., Boston, MA, USA
AD  - Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USAat the time of study
AD  - American Institutes of Research, Chicago, IL, USA
AD  - Analysis Group Inc., Menlo Park, CA, USA
AD  - Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
AD  - Shared Decision Making Resources, Georgetown, ME, USA
AD  - Janssen Scientific Affairs LLC, Raritan, NJ, USA
U2  - PMID: 26390360.
DO  - 10.1185/03007995.2015.1096767
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105000960
T1  - Dietary factors and incident atrial fibrillation: the Framingham Heart Study.
AU  - Shen, Jian
AU  - Johnson, Victor M.
AU  - Sullivan, Lisa M.
AU  - Jacques, Paul F.
AU  - Magnani, Jared W.
AU  - Lubitz, Steven A.
AU  - Pandey, Shivda
AU  - Levy, Daniel
AU  - Vasan, Ramachandran S.
AU  - Quatromoni, Paula A.
AU  - Junyent, Mireia
AU  - Ordovas, Jose M.
AU  - Benjamin, Emelia J.
Y1  - 2011/02//
N1  - Accession Number: 105000960. Language: English. Entry Date: 20110401. Revision Date: 20150819. Publication Type: Journal Article; research; tables/charts. Journal Subset: Allied Health; Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Nutrition. Grant Information: National Heart Lung and Blood Institute, National Institute of Diabetes and Digestive and Kidney Diseases, the US Department of Agriculture Research, the American Heart Association and the NIH. NLM UID: 0376027. 
KW  - Alcohol Drinking
KW  - Atrial Fibrillation
KW  - Caffeine
KW  - Diet
KW  - Dietary Fiber
KW  - Fatty Acids, Unsaturated
KW  - Body Mass Index -- Evaluation
KW  - Confidence Intervals
KW  - Cox Proportional Hazards Model
KW  - Data Analysis Software
KW  - Descriptive Statistics
KW  - Female
KW  - Funding Source
KW  - Human
KW  - Male
KW  - Middle Age
KW  - Multivariate Analysis
KW  - Nutritional Assessment
KW  - Odds Ratio
KW  - Prospective Studies
KW  - Questionnaires
KW  - Secondary Analysis
KW  - Validity
SP  - 261
EP  - 266
JO  - American Journal of Clinical Nutrition
JF  - American Journal of Clinical Nutrition
JA  - AM J CLIN NUTR
VL  - 93
IS  - 2
CY  - Bethesda, Maryland
PB  - American Society for Nutrition
AB  - There have been conflicting reported associations between dietary factors and incident atrial fibrillation (AF). © 2011 American Society for Nutrition.
SN  - 0002-9165
AD  - Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA
AD  - Evans Memorial Department of Medicine, Boston University, Boston, MA
AD  - National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA
AD  - Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA
U2  - PMID: 21106919.
DO  - 10.3945/ajcn.110.001305
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109640179
T1  - Dietary Fat Intake Is Differentially Associated with Risk of Paroxysmal Compared with Sustained Atrial Fibrillation in Women.
AU  - Chiuve, Stephanie E
AU  - Sandhu, Roopinder K
AU  - Moorthy, M Vinayaga
AU  - Glynn, Robert J
AU  - Albert, Christine M
Y1  - 2015/09//9/1/2015
N1  - Accession Number: 109640179. Language: English. Entry Date: 20150923. Revision Date: 20160523. Publication Type: journal article; research; randomized controlled trial. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Nutrition. Grant Information: HL093613/HL/NHLBI NIH HHS/United States. NLM UID: 0404243. 
SP  - 2092
EP  - 2101
JO  - Journal of Nutrition
JF  - Journal of Nutrition
JA  - J NUTR
VL  - 145
IS  - 9
CY  - Bethesda, Maryland
PB  - American Society for Nutrition
AB  - Background: Dietary fats have effects on biological pathways that may influence the development and maintenance of atrial fibrillation (AF). However, associations between n-3 (ω-3) polyunsaturated fatty acids and AF are inconsistent, and data on other dietary fats and AF risk are sparse.Objectives: We examined the association between dietary fatty acid (FA) subclasses and risk of incident AF and explored whether these associations differed for sustained and paroxysmal AF.Methods: We conducted a prospective cohort study in 33,665 women ≥45 y old without cardiovascular disease (CVD) and AF at baseline in 1993. Fat intake was estimated from food frequency questionnaires at baseline and in 2004. Incident AF was confirmed by medical records through October 2013. AF patterns were classified according to the most sustained form of AF within 2 y of diagnosis. Cox proportional hazards models with the use of a competing risk model approach estimated the RR.Results: Over 19.2 y, 1441 cases of incident AF (929 paroxysmal and 467 persistent/chronic) were confirmed. Intakes of total fat and FA subclasses were not associated with risk of AF. Saturated fatty acids (SFAs) and monounsaturated fatty acids (MUFAs) were differentially associated with AF patterns. The RR for a 5% increment of energy from SFAs was 1.47 (95% CI: 1.04, 2.09) for persistent/chronic and 0.85 (95% CI: 0.66, 1.08) for paroxysmal AF (P-difference = 0.01). For MUFAs, the RR for a 5% increment was 0.67 (95% CI: 0.46, 0.98) for persistent/chronic and 1.03 (95% CI: 0.78, 1.34) for paroxysmal AF, although the difference between patterns was not significant (P-difference = 0.07).Conclusions: Dietary fat was not associated with risk of incident AF in women without established CVD or AF. High SFA and low MUFA intakes were associated with greater risk of persistent or chronic, but not paroxysmal, AF. Improving dietary fat quality may play a role in the prevention of sustained forms of AF. The Women's Health Study was registered at clinicaltrials.gov as NCT00000479.
SN  - 0022-3166
U2  - PMID: 26180251.
DO  - 10.3945/jn.115.212860
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105145009
T1  - Dietary fish intake and incident atrial fibrillation (from the Women's Health Initiative)
AU  - Berry JD
AU  - Prineas RJ
AU  - van Horn L
AU  - Passman R
AU  - Larson J
AU  - Goldberger J
AU  - Snetselaar L
AU  - Tinker L
AU  - Liu K
AU  - Lloyd-Jones DM
Y1  - 2010/03/15/
N1  - Accession Number: 105145009. Language: English. Entry Date: 20100409. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Food Frequency Questionnaire (FFQ). NLM UID: 0207277. 
KW  - Atrial Fibrillation -- Etiology
KW  - Diet
KW  - Fatty Acids, Omega-3 -- Administration and Dosage
KW  - Fish
KW  - Aged
KW  - Animals
KW  - Female
KW  - Human
KW  - Middle Age
KW  - Questionnaires
SP  - 844
EP  - 848
JO  - American Journal of Cardiology
JF  - American Journal of Cardiology
JA  - AM J CARDIOL
VL  - 105
IS  - 6
CY  - Philadelphia, Pennsylvania
PB  - Elsevier Inc.
SN  - 0002-9149
AD  - Department of Medicine, Division of Cardiology, University of Texas Southwestern Medical School, Dallas, Texas, USA. jarett.berry@utsouthwestern.edu
U2  - PMID: 20211329.
DO  - 10.1016/j.amjcard.2009.11.039
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106383483
T1  - Dietary fish oil protects against stretch-induced vulnerability to atrial fibrillation in a rabbit model.
AU  - Ninio DM
AU  - Murphy KJ
AU  - Howe PR
AU  - Saint DA
Y1  - 2005/11//
N1  - Accession Number: 106383483. Language: English. Entry Date: 20081219. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts; tracings. Commentary: Mazgalev TN. Drugs, ablation, denervation... and now fish oil: the global war on AF. (J CARDIOVASC ELECTROPHYSIOL) Nov2005; 16 (11): 1195-1199. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Grant Information: Partly funded by the National Health and Medical Research Council of Australia. NLM UID: 9010756. 
KW  - Atrial Fibrillation -- Physiopathology
KW  - Fatty Acids, Omega-3 -- Pharmacodynamics
KW  - Fish Oils -- Pharmacodynamics
KW  - Heart Atrium -- Drug Effects
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Australia
KW  - Data Analysis, Statistical
KW  - Descriptive Statistics
KW  - Electrophysiology
KW  - Models, Biological
KW  - Plant Oils
KW  - Rabbits
KW  - Funding Source
KW  - Animal Studies
SP  - 1189
EP  - 1194
JO  - Journal of Cardiovascular Electrophysiology
JF  - Journal of Cardiovascular Electrophysiology
JA  - J CARDIOVASC ELECTROPHYSIOL
VL  - 16
IS  - 11
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - INTRODUCTION: Dietary fish oil is thought to reduce sudden cardiac death by suppressing ventricular arrhythmias but little is known about its impact on atrial arrhythmias. We examined the effect of dietary fish oil on the rabbit model of stretch-induced vulnerability to atrial fibrillation (AF). METHODS AND RESULTS: Six-week-old rabbits were fed standard rabbit pellets supplemented with 5% tuna fish oil (n = 6) or supplemented with 5% sunflower oil (n = 6) for 12 weeks. Six rabbits raised on the standard diet were used as controls. In Langendorff-perfused hearts intraatrial pressures were increased in a stepwise manner and rapid burst pacing applied to induce AF at increasing intraatrial pressures until AF was sustained (>1 minute). Atrial refractory periods were recorded at each pressure. Increased atrial pressure resulted in a reduction in atrial refractory period and a propensity for induction of sustained AF. Higher pressures were needed to induce and sustain AF in the fish oil group compared with the sunflower oil and control groups. The stretch-induced drop in refractory period was also less marked in the fish oil group. Red blood cell, atrial, and ventricular omega-3 fatty acid levels were significantly higher in the fish oil group. The ratio of atrial n-6/n-3 polyunsaturated fatty acids was 13 +/- 0.9 with sunflower oil and 1.5 +/- 0.01 with fish oil (P < 0.001). CONCLUSIONS: Incorporation of dietary omega-3 fatty acids into atrial tissue reduces stretch-induced susceptibility to AF.
SN  - 1045-3873
AD  - Discipline of Physiology, School of Molecular and Biomedical Science, University of Adelaide, South Australia, Australia 5005; daniel.ninio@adelaide.edu.au
U2  - PMID: 16302902.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105831533
T1  - Direct thrombin inhibition and stroke prevention in elderly patients with atrial fibrillation: experience from the SPORTIF III and V Trials.
AU  - Ford GA
AU  - Choy AM
AU  - Deedwania P
AU  - Karalis DG
AU  - Lindholm CJ
AU  - Pluta W
AU  - Frison L
AU  - Olsson SB
Y1  - 2007/11//
N1  - Accession Number: 105831533. Corporate Author: SPORTIF III, V Investigators. Language: English. Entry Date: 20080307. Revision Date: 20150711. Publication Type: Journal Article; clinical trial; research. Journal Subset: Allied Health; Biomedical; Peer Reviewed; USA. Special Interest: Physical Therapy. NLM UID: 0235266. 
KW  - Amines -- Administration and Dosage
KW  - Atrial Fibrillation -- Complications
KW  - Intracranial Embolism and Thrombosis -- Drug Therapy
KW  - Heterocyclic Compounds -- Administration and Dosage
KW  - Stroke -- Drug Therapy
KW  - Thrombin -- Antagonists and Inhibitors
KW  - Warfarin -- Administration and Dosage
KW  - Administration, Oral
KW  - Age Factors
KW  - Aged
KW  - Aged, 80 and Over
KW  - Alanine Aminotransferase -- Blood
KW  - Alanine Aminotransferase -- Drug Effects
KW  - Amines -- Adverse Effects
KW  - Anticoagulants -- Administration and Dosage
KW  - Anticoagulants -- Adverse Effects
KW  - Biochemical Phenomena -- Drug Effects
KW  - Biochemical Phenomena -- Physiology
KW  - Intracranial Embolism and Thrombosis -- Etiology
KW  - Intracranial Embolism and Thrombosis -- Prevention and Control
KW  - Cerebral Hemorrhage -- Chemically Induced
KW  - Cerebral Hemorrhage -- Epidemiology
KW  - Double-Blind Studies
KW  - Embolism -- Drug Therapy
KW  - Embolism -- Etiology
KW  - Embolism -- Prevention and Control
KW  - Female
KW  - Heterocyclic Compounds -- Adverse Effects
KW  - Male
KW  - Middle Age
KW  - Reproduction
KW  - Sex Factors
KW  - Stroke -- Etiology
KW  - Stroke -- Prevention and Control
KW  - Treatment Outcomes
KW  - Warfarin -- Adverse Effects
KW  - Human
SP  - 2965
EP  - 2971
JO  - Stroke (00392499)
JF  - Stroke (00392499)
JA  - STROKE
VL  - 38
IS  - 11
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - BACKGROUND AND PURPOSE: Warfarin prevents stroke in atrial fibrillation (AF); however, concerns regarding international normalized ratio control and hemorrhage limit its use in the elderly. The oral direct thrombin inhibitors (DTIs) are potential alternatives to warfarin, offering fixed dosing without drug and dietary interactions and the need for international normalized ratio monitoring. Although ximelagatran, a DTI studied in the Stroke Prevention using an ORal Thrombin Inhibitor in atrial Fibrillation trials, has been withdrawn, development of other DTIs continues. We report our experience in elderly high-risk AF patients on ximelagatran compared with warfarin therapy. METHODS: Data from patients with AF and stroke risk factors randomized in Stroke Prevention using an ORal Thrombin Inhibitor in atrial Fibrillation III and V trials to ximelagatran or warfarin were analyzed for stroke/systemic emboli, bleeding, and raised alanine aminotransferase levels in those >or=75 (n=2804) and <75 (n=4525) years. RESULTS: Ximelagatran was as effective as warfarin in reducing stroke/systemic emboli in the elderly (2.23%/y with ximelagatran vs 2.27%/y with warfarin) as in younger patients (1.25%/y vs 1.28%/y). Total bleeds were significantly lower with ximelagatran compared with warfarin in elderly (40% vs 45%, P=0.01) and younger (27% vs 35%, P<0.001) patients. Raised alanine aminotransferase values (>3-fold elevation) among ximelagatran patients were more common in older (7.5% old vs 5.3% young) patients, particularly women (9.5% elderly women vs 6.1% elderly men). CONCLUSIONS: In high-risk elderly AF patients, ximelagatran is as effective as warfarin with less bleeding, but alanine aminotransferase elevations are common, particularly in elderly women. Oral DTIs for stroke prevention show promise in elderly patients.
SN  - 0039-2499
AD  - Institute for Ageing and Health, University of Newcastle upon Tyne, Newcastle upon Tyne, England.
U2  - PMID: 17885258.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104669608
T1  - Do I need to take warfarin for occasional lone atrial fibrillation?
AU  - Zimetbaum, Peter
Y1  - 2011/09//
N1  - Accession Number: 104669608. Language: English. Entry Date: 20110821. Revision Date: 20150711. Publication Type: Journal Article; questions and answers; tables/charts. Journal Subset: Biomedical; USA. NLM UID: 9425723. 
KW  - Atrial Fibrillation
KW  - Severity of Illness Indices
KW  - Warfarin
KW  - Exercise
SP  - 8
EP  - 8
JO  - Harvard Heart Letter
JF  - Harvard Heart Letter
JA  - HARV HEART LETT
VL  - 22
IS  - 1
CY  - Stamford, Connecticut
PB  - Harvard Health Publications
SN  - 1051-5313
AD  - Associate Professor of Medicine Harvard Medical School Beth Israel Deaconess Medical Center
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105497586
T1  - Do older patients receive adequate stroke care? An experience of a neurovascular clinic.
AU  - Kee YK
AU  - Brooks W
AU  - Bhalla A
Y1  - 2009/03//
N1  - Accession Number: 105497586. Language: English. Entry Date: 20091030. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 0234135. 
KW  - Cerebral Ischemia, Transient -- Therapy
KW  - Practice Guidelines
KW  - Stroke -- Therapy
KW  - Aged
KW  - Aged, 80 and Over
KW  - Chi Square Test
KW  - Data Analysis Software
KW  - Magnetic Resonance Imaging
KW  - Mann-Whitney U Test
KW  - Nonparametric Statistics
KW  - Recurrence
KW  - Research Methodology
KW  - Tomography, X-Ray Computed
KW  - Human
SP  - 115
EP  - 118
JO  - Postgraduate Medical Journal
JF  - Postgraduate Medical Journal
JA  - POSTGRAD MED J
VL  - 85
IS  - 1001
PB  - BMJ Publishing Group
AB  - BACKGROUND: National guidelines and government directives have adopted policies for urgent assessment of patients with a transient ischaemic attack or minor stroke not admitted to hospital. The risk of recurrent stroke increases substantially with age, as does the potential benefit of secondary prevention. In order to develop effective strategies for older patients, it is important to identify how stroke care is currently provided for this patient group. METHODS: Between 2004 and 2006, older patients (>75 years) referred to a neurovascular clinic were compared with younger patients (< or =75 years). Sociodemographic details, clinical features, resource use and secondary prevention in a neurovascular clinic were collected. RESULTS: Of 379 patients referred to the clinic, 129 (34%) were given a non-stroke diagnosis. Of the remaining 250 patients, 149 (60%) were < or =75 years. Median time from symptom onset to clinic appointment was similar for the two groups (24 (IQR 15-42) vs 24 (IQR 14-43) days; p = 0.58). Older patients were more likely to be in atrial fibrillation (10.1% vs 22.8%, p<0.001) and have lacunar stroke (34.7% vs 22.1%; p = 0.04). CT rates were similar in the two groups (27.8% vs 80.0%, p = 0.75). Scans were performed more quickly in younger patients (p<0.01). MRI scan rates were higher in younger patients (26% vs 4%, p<0.01), as was carotid Doppler imaging (92% vs 77%, p<0.01). There were no differences in prescribed secondary preventive treatments. Older patients experienced less delay for carotid endarterectomy (49 vs 90 days, p<0.01). Younger patients were more likely to be given advice on weight reduction (30.2% vs 12.9%, p<0.01) and diet (46.3% vs 31.7%, p = 0.02) than older patients. CONCLUSIONS: Older patients were less likely to receive diagnostic investigations and lifestyle modification advice than younger patients. Guidelines need to be adopted to ensure prompt evidence-based stroke care in the outpatient setting.
SN  - 0032-5473
AD  - St Helier Stroke Service, Epsom and St Helier University Hospitals NHS Trust, Carshalton, Surrey, UK. karenkee@doctors.org.uk
U2  - PMID: 19351635.
DO  - 10.1136/pgmj.2008.070607
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108191010
T1  - Dofetilide dose calculation errors in elderly associated with use of the modification of diet in renal disease equation.
AU  - Denetclaw TH
AU  - Oshima N
AU  - Dowling TC
Y1  - 2011/07//2011 Jul
N1  - Accession Number: 108191010. Language: English. Entry Date: 20120323. Revision Date: 20150712. Publication Type: Journal Article; case study; research. Journal Subset: Biomedical; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9203131. 
KW  - Antiarrhythmia Agents -- Administration and Dosage
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Dosage Forms
KW  - Medication Errors -- Prevention and Control
KW  - Phenethylamines -- Administration and Dosage
KW  - Renal Insufficiency -- Diet Therapy
KW  - Sulfonamides -- Administration and Dosage
KW  - Aged, 80 and Over
KW  - Antiarrhythmia Agents -- Adverse Effects
KW  - Antiarrhythmia Agents -- Therapeutic Use
KW  - Atrial Fibrillation -- Complications
KW  - Atrial Fibrillation -- Metabolism
KW  - Atrial Fibrillation -- Therapy
KW  - Combined Modality Therapy
KW  - Creatinine -- Blood
KW  - Creatinine -- Metabolism
KW  - Cardioversion
KW  - Female
KW  - Glomerular Filtration Rate
KW  - Male
KW  - Medication Errors -- Adverse Effects
KW  - Phenethylamines -- Adverse Effects
KW  - Phenethylamines -- Therapeutic Use
KW  - Renal Insufficiency -- Complications
KW  - Severity of Illness Indices
KW  - Sulfonamides -- Adverse Effects
KW  - Sulfonamides -- Therapeutic Use
SP  - e44
EP  - e44
JO  - Annals of Pharmacotherapy
JF  - Annals of Pharmacotherapy
JA  - ANN PHARMACOTHER
VL  - 45
IS  - 7-8
CY  - Thousand Oaks, California
PB  - Sage Publications Inc.
SN  - 1060-0280
AD  - Pharmacy Department, Marin General Hospital, Greenbrae, CA.
U2  - PMID: 21712508.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108191010&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107776489
T1  - Drug News.
AU  - Murdoch, Lu-Ann
Y1  - 2015/02//
N1  - Accession Number: 107776489. Language: English. Entry Date: 20150302. Revision Date: 20150712. Publication Type: Journal Article; pictorial. Journal Subset: Biomedical; Canada. 
KW  - Dapagliflozin -- Therapeutic Use
KW  - Diabetes Mellitus, Type 2 -- Therapy
KW  - Leukemia, Lymphocytic, Chronic -- Therapy
KW  - Pharmacy and Pharmacology
KW  - News
KW  - Pharmaceutical Companies
KW  - Sodium-Glucose Co-Transporter 2 Inhibitors -- Therapeutic Use
KW  - Sodium-Glucose Co-Transporter 2 Inhibitors -- Administration and Dosage
KW  - Diet
KW  - Exercise
KW  - Dapagliflozin -- Administration and Dosage
KW  - Drug Evaluation
KW  - Chlorambucil -- Administration and Dosage
KW  - Antibodies, Monoclonal -- Therapeutic Use
KW  - Leukemia, Lymphocytic, Chronic -- Physiopathology
KW  - Antibodies, Monoclonal -- Administration and Dosage
KW  - Antineoplastic Agents -- Administration and Dosage
KW  - Psoriasis -- Therapy
KW  - Adult
KW  - Phosphodiesterase Inhibitors -- Administration and Dosage
KW  - Phosphodiesterase Inhibitors -- Therapeutic Use
KW  - Depression -- Therapy
KW  - Antidepressive Agents -- Administration and Dosage
KW  - Neurotransmitter Agents
KW  - Drug Approval
KW  - Injections
KW  - Castleman's Disease -- Therapy
KW  - Aspirin -- Therapeutic Use
KW  - Parkinson Disease -- Therapy
KW  - Antiparkinson Agents -- Administration and Dosage
KW  - Venous Thromboembolism -- Therapy
KW  - Pulmonary Embolism -- Therapy
KW  - Recurrence
KW  - Atrial Fibrillation -- Complications
KW  - Anticoagulants -- Therapeutic Use
KW  - Macular Degeneration -- Therapy
KW  - Edema -- Therapy
SP  - 8
EP  - 10
JO  - Pharmacy Practice
JF  - Pharmacy Practice
JA  - PHARM PRACT (08292809)
VL  - 2
IS  - 1
CY  - Toronto, Ontario
PB  - Rogers Media Inc.
SN  - 0829-2809
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104438516
T1  - DTB select.
Y1  - 2012/07//
N1  - Accession Number: 104438516. Language: English. Entry Date: 20121207. Revision Date: 20150711. Publication Type: Journal Article; abstract. Journal Subset: Biomedical; Europe; UK & Ireland. NLM UID: 0112037. 
KW  - Administration, Oral
KW  - Administration, Topical
KW  - Adrenergic Beta-Antagonists -- Adverse Effects
KW  - Anticoagulants -- Administration and Dosage
KW  - Antifungal Agents -- Administration and Dosage
KW  - Asthma
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Botulinum Toxins -- Therapeutic Use
KW  - Breast Neoplasms -- Rehabilitation
KW  - Colonic Neoplasms -- Rehabilitation
KW  - Contraceptive Agents -- Adverse Effects
KW  - Dermatomycoses -- Drug Therapy
KW  - Diabetes Mellitus, Type 2 -- Drug Therapy
KW  - Drug Monitoring
KW  - Exercise
KW  - Gastrointestinal Hemorrhage -- Risk Factors
KW  - Magnesium -- Blood
KW  - Medical Orders
KW  - Medication Errors
KW  - Metformin -- Adverse Effects
KW  - Migraine -- Prevention and Control
KW  - Peptic Ulcer -- Complications
KW  - Platelet Aggregation Inhibitors -- Adverse Effects
KW  - Premedication
KW  - Proton Pump Inhibitors -- Adverse Effects
KW  - Thrombosis -- Risk Factors
KW  - Treatment Errors
SP  - 74
EP  - 77
JO  - Drug & Therapeutics Bulletin
JF  - Drug & Therapeutics Bulletin
JA  - DRUG THER BULL
VL  - 50
IS  - 7
PB  - BMJ Publishing Group
SN  - 0012-6543
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108221544
T1  - EBP CME tests.
Y1  - 2011/12//2011 Dec
N1  - Accession Number: 108221544. Language: English. Entry Date: 20120127. Revision Date: 20150712. Publication Type: Journal Article; CEU; exam questions. Journal Subset: Biomedical; USA. Special Interest: Evidence-Based Practice. NLM UID: 100894030. 
KW  - Aerobic Exercises
KW  - Antiinflammatory Agents, Non-Steroidal -- Adverse Effects
KW  - Atrial Fibrillation
KW  - Back Pain -- Therapy
KW  - Bone and Bones -- Physiology
KW  - Depression -- Drug Therapy -- In Pregnancy
KW  - Diabetes Mellitus, Type 2 -- Therapy
KW  - Disease Surveillance
KW  - Heart Failure -- Complications
KW  - Heart Rate
KW  - Heat
KW  - Infusions, Intravenous
KW  - Lipoma -- Complications
KW  - Oxytocin -- Administration and Dosage
KW  - Syndrome
KW  - Wound Healing
KW  - Education, Continuing (Credit)
KW  - Female
KW  - Pregnancy
SP  - 15
EP  - 15
JO  - Evidence-Based Practice
JF  - Evidence-Based Practice
JA  - EVID BASED PRACT
VL  - 14
IS  - 12
CY  - East Windsor, New Jersey
PB  - McGraw Hill Financial, Inc.
SN  - 1095-4120
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 112362590
T1  - Editor's view.
Y1  - 2016/01//
N1  - Accession Number: 112362590. Language: English. Entry Date: 20160126. Revision Date: 20160212. Publication Type: Article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Gerontologic Care. NLM UID: 0375655. 
KW  - Aging
KW  - Yoga
KW  - Anticoagulants
KW  - Atrial Fibrillation
KW  - Serial Publications
SP  - 1
EP  - 1
JO  - Age & Ageing
JF  - Age & Ageing
JA  - AGE AGEING
VL  - 45
IS  - 1
PB  - Oxford University Press / USA
SN  - 0002-0729
DO  - 10.1093/ageing/afv186
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104640332
T1  - Edoxaban: A New Oral Direct Factor Xa Inhibitor.
AU  - Camm, John
AU  - Bounameaux, Henri
Y1  - 2011/07/15/
N1  - Accession Number: 104640332. Language: English. Entry Date: 20111207. Revision Date: 20150711. Publication Type: Journal Article; review; tables/charts. Journal Subset: Australia & New Zealand; Biomedical; Peer Reviewed. Special Interest: Critical Care; Perioperative Care. Grant Information: Medical writing and editing support funded by Daiichi Sankyo Europe GmbH was provided by Simon Lancaster and Ray Hill, from (/¡Science Communications, a Wolters Kluwer business. Professor Camm has received research grants from Pt'izer, BMS, Daiichi Sankyo. St Jude. Servier and Sanofi-aventis, and honoraria for Speakers Bureaus and Advisory Boards from Cardiome, Sanofi-aventis, Menarini, Daiichi Sankyo, Pfizer. Merck, BMS, ARYx, Xention, Servier, Novartis, Actelion, Medtronic and Boston Scientific. Professor Bounameaux discloses having received a research grant from Sanofi-aventis, and honoraria for consulting/lecturing from Bayer-Schering Phamia, Boehringer-Ingelheim, BMS, GSK, Sanofi-aventis, Servier, Daiichi-Sankyo, Canonpharma and Pfizer.. NLM UID: 7600076. 
KW  - Anticoagulants -- Therapeutic Use
KW  - Stroke -- Prevention and Control
KW  - Thromboembolism -- Prevention and Control
KW  - Atrial Fibrillation -- Complications
KW  - Thrombolytic Therapy -- Methods
KW  - Clinical Trials
KW  - Thromboembolism -- Physiopathology
KW  - Anticoagulants -- Pharmacokinetics
KW  - Anticoagulants -- Pharmacodynamics
KW  - Safety
KW  - Orthopedic Surgery
KW  - Funding Source
SP  - 1503
EP  - 1526
JO  - Drugs
JF  - Drugs
JA  - DRUGS
VL  - 71
IS  - 12
PB  - Springer Science & Business Media B.V.
AB  - Edoxaban is an oral direct factor Xa inhibitor that is currently undergoing investigation in phase III clinical trials for the prevention of stroke in patients with atrial fibrillation (AF) and for the prevention and treatment of venous thromboembolic events (VTE). Factor Xa is an attractive target for anticoagulant treatment, as it is the primary and rate-limiting source of amplification in the coagulation cascade. Edoxaban is a competitive inhibitor of factor Xa and has >10 000-fold greater selectivity for factor Xa relative to thrombin. In phase I clinical trials, the anticoagulant effects of edoxaban included dose-dependent increases in activated partial thromboplastin time and prothrombin time following single edoxaban doses of 10-150 mg and after multiple ascending doses (60 mg twice daily, 90 mg daily and 120mg daily). The anticoagulant effects of edoxaban were rapid in onset (time to peak plasma concentration 1-2 hours) and sustained for up to 24 hours. Prolongation of bleeding time in 8% of subjects was >9.5 minutes (none of which appeared to be clinically significant) 2 hours after initial dosing, and was independent of edoxaban dose, formulation or dietary state. In general, plasma edoxaban concentrations were linearly correlated with coagulation parameters. Phase II clinical trials in patients with AF and VTE suggest that the edoxaban 30 mg once-daily and 60 mg once-daily regimens had a similar or better safety profile compared with dose-adjusted warfarin (international normalized ratio 2.0-3.0) in terms of bleeding events, and that edoxaban was not associated with hepatotoxicity. In addition, edoxaban was associated with statistically significant dose-dependent reductions in VTE after orthopaedic surgery compared with placebo or dalteparin sodium. Further clinical investigation of the efficacy and safety of once-daily edoxaban is being conducted in phase III clinical trials in comparison with warfarin in patients with AF in the phase III ENGAGE AF-TIMI 48 trial (NCT00781391), and in comparison with low-molecular weight heparin/warfarin in the prevention of recurrent VTE in patients with symptomatic deep vein thrombosis and/or pulmonary embolism in the HOKUSAI VTE trial (NCT00986154).
SN  - 0012-6667
AD  - Division of Clinical Sciences, St George's University of London, London
AD  - Department of Internal Medicine, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland
U2  - PMID: 21861537.
DO  - 10.2165/11595540-000000000-00000
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104681778
T1  - Effect of dietary fish oil on atrial fibrillation after cardiac surgery.
AU  - Farquharson AL
AU  - Metcalf RG
AU  - Sanders P
AU  - Stuklis R
AU  - Edwards JR
AU  - Gibson RA
AU  - Cleland LG
AU  - Sullivan TR
AU  - James MJ
AU  - Young GD
Y1  - 2011/09/15/
N1  - Accession Number: 104681778. Language: English. Entry Date: 20111111. Revision Date: 20150711. Publication Type: Journal Article; research; randomized controlled trial. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0207277. 
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Fish Oils -- Therapeutic Use
KW  - Heart Surgery
KW  - Postoperative Complications -- Prevention and Control
KW  - Aged
KW  - Cox Proportional Hazards Model
KW  - Dietary Supplements
KW  - Double-Blind Studies
KW  - Female
KW  - Human
KW  - Incidence
KW  - Intensive Care Units -- Statistics and Numerical Data
KW  - Length of Stay -- Statistics and Numerical Data
KW  - Logistic Regression
KW  - Male
KW  - Middle Age
KW  - Placebos
KW  - Prospective Studies
KW  - Randomized Controlled Trials
KW  - Treatment Outcomes
SP  - 851
EP  - 856
JO  - American Journal of Cardiology
JF  - American Journal of Cardiology
JA  - AM J CARDIOL
VL  - 108
IS  - 6
CY  - Philadelphia, Pennsylvania
PB  - Elsevier Inc.
SN  - 0002-9149
AD  - Discipline of Medicine, University of Adelaide, Adelaide, Australia.
U2  - PMID: 21762871.
DO  - 10.1016/j.amjcard.2011.04.036
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 104116952
T1  - Effect of weight reduction and cardiometabolic risk factor management on symptom burden and severity in patients with atrial fibrillation: a randomized clinical trial.
AU  - Abed, Hany S
AU  - Wittert, Gary A
AU  - Leong, Darryl P
AU  - Shirazi, Masoumeh G
AU  - Bahrami, Bobak
AU  - Middeldorp, Melissa E
AU  - Lorimer, Michelle F
AU  - Lau, Dennis H
AU  - Antic, Nicholas A
AU  - Brooks, Anthony G
AU  - Abhayaratna, Walter P
AU  - Kalman, Jonathan M
AU  - Sanders, Prashanthan
Y1  - 2013/11/20/
N1  - Accession Number: 104116952. Language: English. Entry Date: 20140131. Revision Date: 20150710. Publication Type: Journal Article; research; randomized controlled trial. Commentary: Wyse D. George. In overweight or obese patients with atrial fibrillation, a weight reduction program reduced symptoms. (ACP J CLUB) 3/18/2014; 160 (6): 1-1. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7501160. 
KW  - Atrial Fibrillation -- Diet Therapy
KW  - Diet, Reducing
KW  - Obesity -- Diet Therapy
KW  - Weight Loss
KW  - Aged
KW  - Atrial Fibrillation -- Complications
KW  - Echocardiography
KW  - Fish Oils -- Administration and Dosage
KW  - Heart Atrium -- Pathology
KW  - Heart Atrium -- Ultrasonography
KW  - Human
KW  - Life Style
KW  - Male
KW  - Middle Age
KW  - Obesity -- Complications
KW  - Risk Factors
KW  - Severity of Illness Indices
KW  - Treatment Outcomes
SP  - 2050
EP  - 2060
JO  - JAMA: Journal of the American Medical Association
JF  - JAMA: Journal of the American Medical Association
JA  - JAMA
VL  - 310
IS  - 19
CY  - Chicago, Illinois
PB  - American Medical Association
SN  - 0098-7484
AD  - Centre for Heart Rhythm Disorders, University of Adelaide, and Royal Adelaide Hospital, Adelaide, Australia2Department of Medicine, University of Adelaide, and Royal Adelaide Hospital, Adelaide, Australia.
U2  - PMID: 24240932.
DO  - 10.1001/jama.2013.280521
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104252436
T1  - Effect of Yoga on Arrhythmia Burden, Anxiety, Depression, and Quality of Life in Paroxysmal Atrial Fibrillation: The YOGA My Heart Study.
AU  - Lakkireddy, Dhanunjaya
AU  - Atkins, Donita
AU  - Pillarisetti, Jayasree
AU  - Ryschon, Kay
AU  - Bommana, Sudharani
AU  - Drisko, Jeanne
AU  - Vanga, Subbareddy
AU  - Dawn, Buddhadeb
Y1  - 2013/03/19/
N1  - Accession Number: 104252436. Language: English. Entry Date: 20130517. Revision Date: 20150711. Publication Type: Journal Article; research. Commentary: Dimarco John P. Value of Yoga Training in Paroxysmal Atrial Fibrillation. (CLIN CARDIOL ALERT) May2013; 32 (5): 39-40. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 8301365. 
KW  - Anxiety -- Therapy
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Atrial Fibrillation -- Therapy
KW  - Depression -- Therapy
KW  - Quality of Life
KW  - Yoga
KW  - Female
KW  - Human
KW  - Male
KW  - Middle Age
KW  - Prospective Studies
SP  - 1177
EP  - 1182
JO  - Journal of the American College of Cardiology (JACC)
JF  - Journal of the American College of Cardiology (JACC)
JA  - J AM COLL CARDIOL
VL  - 61
IS  - 11
CY  - New York, New York
PB  - Elsevier Science
SN  - 0735-1097
AD  - Division of Cardiovascular Diseases, Cardiovascular Research Institute, University of Kansas Hospital & Medical Center, Kansas City, Kansas. Electronic address: dlakkireddy@mac.md.
U2  - PMID: 23375926.
DO  - 10.1016/j.jacc.2012.11.060
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106038940
T1  - Effects of a selective al-adenosine receptor agonist on heart rate and heart rate variability during permanent atrial fibrillation.
AU  - Piot O
AU  - Chauvel C
AU  - Lazarus A
AU  - Pellerin D
AU  - David D
AU  - Leneveut-Ledoux L
AU  - Guize L
AU  - Le Heuzey J
Y1  - 1998/11/15/
N1  - Accession Number: 106038940. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Allied Health; Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7803944. 
SP  - 2459
EP  - 2464
JO  - Pacing & Clinical Electrophysiology
JF  - Pacing & Clinical Electrophysiology
JA  - PACING CLIN ELECTROPHYSIOL
VL  - 21
IS  - 11P2
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Background: Mean heart rote and irregularity of the rate, i.e., heart rate variability (HBV), are two aspects of heart rate during atrial fibrillation (AF). An important goal of AF therapy is to control mean heart rate during exercise: the determinants of HRV during AF remain poorly known although its prognostic value has been established. Objectives: To investigate the effects of a stable, long-acting, selective Al-adenosine receptor agonist. SDZ WAG994, on heart rate during exercise and on HRV Methods: In a multicenter, double-blind, randomized, placebo-controlled, parallel group study, patients with permanent AF performed a symptom-limited exercise test and underwent 24-hour EGG monitoring on day 1 during treatment with placebo, and on day 2 during treatment with either placebo or 2 mg SDZWAG994 orally. Changes in mean heart rate during exercise and changes in HRV in- dices between day 1 and day 2 were compared between the two groups. Results: Thirty-two patients (64 ± 8 years; 81% male; 25% in NYHA Gloss II; 38% with no structural heart disease) were included in the study. During active treatments, heart rote remained unchanged at rest and increased significantly during exercise. A significant daytime increase in short-term HRV indices (DpNN50 = 4.5% P 0.01; DrMSSD = 6% P = 0.03; DSDNN Index = 6% P = 0.02) occurred during active treatment. Conclusions: Selective Al -adenosine receptor agonism with SDZ/WAG994 limits the increase in mean heart rate during exercise in patients with AF. In addition, this agonist selectively increases short-term HRV indices, suggesting that pNN5O, rMSSD, and SDNN reflect vagal influences during AF.
SN  - 0147-8389
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - THES
ID  - 109870678
T1  - Effects of positional changes on selected physiological and psychological measurements in clients with atrial fibrillation.
AU  - Collins AS
Y1  - 1991/01//
N1  - Accession Number: 109870678. Language: English. Entry Date: 19940401. Revision Date: 20150923. Publication Type: Doctoral Dissertation; research. 
KW  - Patient Positioning
KW  - Atrial Fibrillation
KW  - Balance, Postural
KW  - Heart Failure
KW  - Neuman Systems Model
KW  - Age Factors
KW  - Physiological Studies
KW  - Repeated Measures
KW  - Psychological Tests
KW  - Physiological Theory
KW  - Middle Age
KW  - Aged
KW  - Aged, 80 and Over
KW  - Human
SP  - 120 p
EP  - 120 p
JO  - Effects of Positional Changes on Selected Physiological & Psychological Measurements in Clients With Atrial Fibrillation
JF  - Effects of Positional Changes on Selected Physiological & Psychological Measurements in Clients With Atrial Fibrillation
PB  - UNIVERSITY OF ALABAMA AT BIRMINGHAM
AB  - Nurses advocate changes in position to promote comfort, improve sensory stimulation, and prevent complications of bedrest. One specific situation for which dangling has been prescribed is in the transition from bedrest to activity. The purpose of this study was the scientific observation of human responses measured with clients with atrial fibrillation, accompanying congestive heart failure, during position changes. The conceptual framework used to guide this study was based on the Neuman systems model, which was enhanced by physiologic theory. The sample consisted of 26 clients between the ages of 54 and 90 years. These patients met multiple exclusion criteria for the inclusion in the study. The clients were turned left, right, and dangled with feet moving. Prior to the position changes, the patient rested 5 minutes in bed. Baseline perceived level of exertion (psychological measurement) and blood pressure (ventricular response rate, rate pressure product physiological measurements) were obtained at rest. These same measurements were obtained while the client was on the right side, left side, or dangling position at.5 minute into position, 2 and 4 minutes into the position change. Repeated measures analyses of variance revealed statistically significant results for the.5 minute measurement on systolic and diastolic blood pressures, on the left side and dangling. However, the mean drop was 13 mmgHg and 8 mmgHg for these positions which would not cause clinical symptoms. A Wilcoxin non-parametric test was performed which revealed a difference in client rating of exertion between baseline and dangling. These findings tended to support the changes of position as being safe for clients experiencing the concurrent stressors of position change and atrial fibrillation accompanying congestive heart failure. Recommendations included replicating the study for the client with multiple triggers for atrial fibrillation, and inclusion of the chair rest and standing position in the methodology. Also, it was recommended that research pertinent to quality of life and the stressor of atrial fibrillation could improve nursing interventions relevant to this phenomena.
AV  - UMI Order PUZ9218386
M1  - D.S.N.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107890873
T1  - Efficacy and Safety of Dabigatran Compared With Warfarin in Relation to Baseline Renal Function in Patients With Atrial Fibrillation: A RE-LY (Randomized Evaluation of Long-term Anticoagulation Therapy) Trial Analysis.
AU  - Hijazi, Ziad
AU  - Hohnloser, Stefan H
AU  - Oldgren, Jonas
AU  - Andersson, Ulrika
AU  - Connolly, Stuart J
AU  - Eikelboom, John W
AU  - Ezekowitz, Michael D
AU  - Reilly, Paul A
AU  - Siegbahn, Agneta
AU  - Yusuf, Salim
AU  - Wallentin, Lars
Y1  - 2014/03/04/
N1  - Accession Number: 107890873. Language: English. Entry Date: 20140606. Revision Date: 20150712. Publication Type: Journal Article; research; randomized controlled trial. Commentary: Sarvananthan Sajiram, Punjabi Prakash P. In atrial fibrillation, dabigatran had similar efficacy to warfarin but caused less bleeding in higher GFR. (ACP J CLUB) 8/1/2014; 161 (4): 1-1. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0147763. 
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Atrial Fibrillation -- Physiopathology
KW  - Heterocyclic Compounds -- Adverse Effects
KW  - Heterocyclic Compounds -- Therapeutic Use
KW  - Kidney -- Physiology
KW  - Warfarin -- Adverse Effects
KW  - Warfarin -- Therapeutic Use
KW  - Alanine
KW  - Aged
KW  - Aged, 80 and Over
KW  - Anticoagulants -- Adverse Effects
KW  - Anticoagulants -- Pharmacodynamics
KW  - Anticoagulants -- Therapeutic Use
KW  - Atrial Fibrillation -- Complications
KW  - Heterocyclic Compounds -- Pharmacodynamics
KW  - Dose-Response Relationship, Drug
KW  - Embolism -- Epidemiology
KW  - Female
KW  - Glomerular Filtration Rate -- Drug Effects
KW  - Glomerular Filtration Rate -- Physiology
KW  - Human
KW  - International Relations
KW  - Kidney -- Drug Effects
KW  - Male
KW  - Middle Age
KW  - Models, Biological
KW  - Risk Factors
KW  - Stroke -- Epidemiology
KW  - Treatment Outcomes
KW  - Warfarin -- Pharmacodynamics
KW  - Alanine -- Adverse Effects
KW  - Alanine -- Pharmacodynamics
KW  - Alanine -- Therapeutic Use
SP  - 961
EP  - 970
JO  - Circulation
JF  - Circulation
JA  - CIRCULATION
VL  - 129
IS  - 9
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - BACKGROUND: Renal impairment increases the risk of stroke and bleeding in patients with atrial fibrillation. In the Randomized Evaluation of Long-Term Anticoagulant Therapy (RELY) trial, dabigatran, with ~=80% renal elimination, displayed superiority over warfarin for prevention of stroke and systemic embolism in the 150-mg dose and significantly less major bleeding in the 110-mg dose in 18 113 patients with nonvalvular atrial fibrillation. This prespecified study investigated these outcomes in relation to renal function. METHODS AND RESULTS: Glomerular filtration rate was estimated with the Cockcroft-Gault, Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), and Modification of Diet in Renal Disease (MDRD) equations in all randomized patients with available creatinine at baseline (n=17 951), and cystatin C-based glomerular filtration rate was estimated in a subpopulation with measurements available (n=6190). A glomerular filtration rate >=80, 50 to <80, and <50 mL/min was estimated in 32.6%, 47.6%, and 19.8% and in 21.6%, 59.6%, and 18.8% of patients based on Cockcroft-Gault and CKD-EPI, respectively. Rates of stroke or systemic embolism, major bleeding, and all-cause mortality increased as renal function decreased. The rates of stroke or systemic embolism were lower with dabigatran 150 mg and similar with 110 mg twice daily compared with warfarin, without significant heterogeneity in subgroups defined by renal function (interaction P>0.1 for all). For the outcome of major bleeding, there were significant interactions between treatment and renal function according to CKD-EPI and MDRD equations, respectively (P<0.05). The relative reduction in major bleeding with either dabigatran dose compared with warfarin was greater in patients with glomerular filtration rate >=80 mL/min. CONCLUSIONS: The efficacy of both dosages of dabigatran was consistent with the overall trial irrespective of renal function. However, with the CKD-EPI and MDRD equations, both dabigatran dosages displayed significantly lower rates of major bleeding in patients with glomerular filtration rate >=80 mL/min. CLINICAL TRIAL REGISTRATION URL: http://www.clinicaltrials.gov. Unique identifier: NCT00262600.
SN  - 0009-7322
AD  - From Uppsala Clinical Research Center (Z.H., J.O., U.A., A.S., L.W.), Department of Medical Sciences, Cardiology (Z.H., J.O., L.W.), and Department of Medical Sciences, Clinical Chemistry (A.S.), Uppsala University, Sweden; Department of Cardiology, J.W. Goethe University, Frankfurt, Germany (S.H.H.); Population Health Research Institute, Hamilton, Ontario, Canada (S.J.C., J.W.E., S.Y.); Thomas Jefferson Medical College and the Heart Center, Wynnewood, PA (M.D.E.); and Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT (P.A.R.).
U2  - PMID: 24323795.
DO  - 10.1161/CIRCULATIONAHA.113.003628
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104839124
T1  - Efficacy of Acupuncture in Preventing Atrial Fibrillation Recurrences After Electrical Cardioversion.
AU  - Lomuscio, Alberto
AU  - Belletti, Sebastiano
AU  - Battezzati, Pier Maria
AU  - Lombardi, Federico
Y1  - 2011/03//
N1  - Accession Number: 104839124. Language: English. Entry Date: 20110405. Revision Date: 20150711. Publication Type: Journal Article; pictorial; research; tables/charts. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9010756. 
KW  - Atrial Fibrillation -- Therapy
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Acupuncture -- Methods
KW  - Cardioversion
KW  - Medicine, Chinese Traditional
KW  - Acupuncture Points
KW  - Amiodarone -- Therapeutic Use
KW  - Log-Rank Test
KW  - Human
KW  - Cox Proportional Hazards Model
KW  - Outpatients
KW  - Male
KW  - Female
KW  - Middle Age
KW  - Aged
KW  - Descriptive Statistics
KW  - Mann-Whitney U Test
KW  - Kruskal-Wallis Test
KW  - Fisher's Exact Test
KW  - Post Hoc Analysis
KW  - Confidence Intervals
KW  - Kaplan-Meier Estimator
KW  - Data Analysis Software
KW  - Univariate Statistics
KW  - Treatment Outcomes
SP  - 241
EP  - 247
JO  - Journal of Cardiovascular Electrophysiology
JF  - Journal of Cardiovascular Electrophysiology
JA  - J CARDIOVASC ELECTROPHYSIOL
VL  - 22
IS  - 3
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - . Introduction: In traditional Chinese medicine, stimulation of the Neiguan spot has been utilized to treat palpitations. We evaluated whether acupuncture might prevent or reduce the rate of arrhythmia recurrences in patients with persistent atrial fibrillation (AF). Methods and Results: We studied 80 patients with persistent AF after restoring sinus rhythm with electrical cardioversion. Twenty-six subjects who were already on amiodarone treatment constituted the AMIO reference group. The remaining patients were randomly allocated to receive acupuncture (ACU group, n = 17), sham acupuncture (ACU-sham group, n = 13), or neither acupuncture nor antiarrhythmic therapy (CONTROL group, n = 24). Patients in the ACU and ACU-sham groups attended 10 acupuncture sessions on a once-a-week basis. Only in the former group the Neiguan, Shenmen, and Xinshu spots were punctured. During a 12-month follow-up, AF recurred in 35 patients. Cumulative AF recurrence rates in the AMIO, ACU, ACU-sham, and CONTROL patients were 27%, 35%, 69%, and 54%, respectively (P = 0.0075, log-rank test). Ejection fraction (P = 0.0005), hypertension (0.0293), and left atrial diameter (P = 0.0361) were also significantly associated with AF recurrence. Compared with AMIO group, recurrence rate was similar in ACU patients (hazard ratio: 1.15, 95% CI: 0.38-3.49; P = 0.801) but significantly higher in ACU-sham and CONTROL patients (3.77, 1.39-10; P = 0.009 and 3.15, 1.23-8.06; P = 0.017, respectively) after adjustment for ejection fraction, hypertension, and left atrial diameter using Cox modeling. Conclusion: Our data indicate that acupuncture treatment prevents arrhythmic recurrences after cardioversion in patients with persistent AF. This minimally invasive procedure was safe and well tolerated. (J Cardiovasc Electrophysiol, Vol. 22, pp. 241-247, March 2011)
SN  - 1045-3873
AD  - Cardiologia
AD  - Medicina Interna VI, Osp. San Paolo, Dipartimento di Medicina, Chirurgia e Odontoiatria, Università degli Studi di Milano, Milan, Italy
U2  - PMID: 20807278.
DO  - 10.1111/j.1540-8167.2010.01878.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105989537
T1  - Efficacy of CRT on exercise tolerance and disease progression: the importance of AV junction ablation in patients with atrial fibrillation...Maurizio Gasparini, MD
AU  - Block PC
Y1  - 2006/11//2006 Nov
N1  - Accession Number: 105989537. Language: English. Entry Date: 20080222. Revision Date: 20150711. Publication Type: Journal Article; CEU; interview; tables/charts; website. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Critical Care. NLM UID: 101265145. 
KW  - Atrial Fibrillation -- Therapy
KW  - Catheter Ablation
KW  - Exercise Tolerance
KW  - Defibrillators, Implantable
KW  - Education, Continuing (Credit)
KW  - Heart Failure -- Therapy
KW  - Ventricular Ejection Fraction
KW  - World Wide Web
SP  - 39
EP  - 42
JO  - ACC Cardiosource Review Journal
JF  - ACC Cardiosource Review Journal
JA  - ACC CARDIOSOURCE REV J
VL  - 15
IS  - 11
CY  - New York, New York
PB  - Elsevier Science
SN  - 1556-8571
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105879520
T1  - Egg consumption and risk of heart failure in the Physicians' Health Study.
AU  - Djoussé L
AU  - Gaziano JM
Y1  - 2008/01/29/
N1  - Accession Number: 105879520. Language: English. Entry Date: 20080404. Revision Date: 20150711. Publication Type: Journal Article; research. Commentary: Rubenfire M. [Commentary on] Egg consumption and risk of heart failure in the Physicians' Health Study. (ACC CARDIOSOURCE REV J) 2008 Apr; 17 (4): 36-36. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0147763. 
KW  - Eggs -- Adverse Effects
KW  - Heart Failure -- Etiology
KW  - Adult
KW  - Aged
KW  - Aged, 80 and Over
KW  - Eating Behavior
KW  - Eggs
KW  - Heart Failure -- Epidemiology
KW  - Male
KW  - Middle Age
KW  - Physicians
KW  - Prospective Studies
KW  - Questionnaires
KW  - Risk Factors
KW  - Human
SP  - 512
EP  - 516
JO  - Circulation
JF  - Circulation
JA  - CIRCULATION
VL  - 117
IS  - 4
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - BACKGROUND: Reduction in dietary cholesterol is widely recommended for the prevention of cardiovascular disease. Although eggs are important sources of dietary cholesterol and other nutrients, little is known about the association between egg consumption and heart failure (HF) risk. METHODS AND RESULTS: In a prospective cohort study of 21 275 participants from the Physicians' Health Study I, we examined the association between egg consumption and the risk of HF. Egg consumption was assessed with the use of a simple abbreviated food questionnaire, and we used Cox regression to estimate relative risks of HF. After an average follow-up of 20.4 years, a total of 1084 new HF cases occurred in this cohort. Although egg consumption up to 6 times per week was not associated with incident HF, egg consumption of > or = 7 per week was associated with an increased risk of HF. Compared with subjects who reported egg consumption of < 1 per week, hazard ratios (95% confidence intervals) for HF were 1.28 (1.02 to 1.61) and 1.64 (1.08 to 2.49) for egg consumption of 1 per day and > or = 2 per day, respectively, after adjustment for age, body mass index, smoking, alcohol consumption, exercise, and history of atrial fibrillation, hypertension, valvular heart disease, and hypercholesterolemia. Similar results were obtained for HF without antecedent myocardial infarction. CONCLUSIONS: Our data suggest that infrequent egg consumption is not associated with the risk of HF. However, egg consumption of > or = 1 per day is related to an increased risk of HF among US male physicians.
SN  - 0009-7322
AD  - Division of Aging, Brigham and Women's Hospital and Harvard Medical School, 1620 Tremont St, Third Floor, Boston MA 02120, USA. ldjousse@rics.bwh.harvard.edu
U2  - PMID: 18195171.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109592507
T1  - Electrophysiological, Electroanatomical, and Structural Remodeling of the Atria as Consequences of Sustained Obesity.
AU  - Mahajan, Rajiv
AU  - Lau, Dennis H
AU  - Brooks, Anthony G
AU  - Shipp, Nicholas J
AU  - Manavis, Jim
AU  - Wood, John P M
AU  - Finnie, John W
AU  - Samuel, Chrishan S
AU  - Royce, Simon G
AU  - Twomey, Darragh J
AU  - Thanigaimani, Shivshanker
AU  - Kalman, Jonathan M
AU  - Sanders, Prashanthan
Y1  - 2015/07/07/
N1  - Accession Number: 109592507. Language: English. Entry Date: 20150923. Revision Date: 20150925. Publication Type: journal article. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 8301365. 
SP  - 1
EP  - 11
JO  - Journal of the American College of Cardiology (JACC)
JF  - Journal of the American College of Cardiology (JACC)
JA  - J AM COLL CARDIOL
VL  - 66
IS  - 1
CY  - New York, New York
PB  - Elsevier Science
AB  - Background: Obesity and atrial fibrillation (AF) are public health issues with significant consequences.Objectives: This study sought to delineate the development of global electrophysiological and structural substrate for AF in sustained obesity.Methods: Ten sheep fed ad libitum calorie-dense diet to induce obesity over 36 weeks were maintained in this state for another 36 weeks; 10 lean sheep with carefully controlled weight served as controls. All sheep underwent electrophysiological and electroanatomic mapping; hemodynamic and imaging assessment (echocardiography and dual-energy x-ray absorptiometry); and histology and molecular evaluation. Evaluation included atrial voltage, conduction velocity (CV), and refractoriness (7 sites, 2 cycle lengths), vulnerability for AF, fatty infiltration, atrial fibrosis, and atrial transforming growth factor (TGF)-β1 expression.Results: Compared with age-matched controls, chronically obese sheep demonstrated greater total body fat (p < 0.001); LA volume (p < 0.001); LA pressure (p < 0.001), and PA pressures (p < 0.001); reduced atrial CV (LA p < 0.001) with increased conduction heterogeneity (p < 0.001); increased fractionated electrograms (p < 0.001); decreased posterior LA voltage (p < 0.001) and increased voltage heterogeneity (p < 0.001); no change in the effective refractory period (ERP) (p > 0.8) or ERP heterogeneity (p > 0.3). Obesity was associated with more episodes (p = 0.02), prolongation (p = 0.01), and greater cumulative duration (p = 0.02) of AF. Epicardial fat infiltrated the posterior LA in the obese group (p < 0.001), consistent with reduced endocardial voltage in this region. Atrial fibrosis (p = 0.03) and TGF-β1 protein (p = 0.002) were increased in the obese group.Conclusions: Sustained obesity results in global biatrial endocardial remodeling characterized by LA enlargement, conduction abnormalities, fractionated electrograms, increased profibrotic TGF-β1 expression, interstitial atrial fibrosis, and increased propensity for AF. Obesity was associated with reduced posterior LA endocardial voltage and infiltration of contiguous posterior LA muscle by epicardial fat, representing a unique substrate for AF.
SN  - 0735-1097
U2  - PMID: 26139051.
DO  - 10.1016/j.jacc.2015.04.058
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105575719
T1  - Elevated International Normalized Ratio after concurrent ingestion of cranberry sauce and warfarin.
AU  - Mergenhagen KA
AU  - Sherman O
Y1  - 2008/11/15/
N1  - Accession Number: 105575719. Language: English. Entry Date: 20090116. Revision Date: 20150711. Publication Type: Journal Article; case study. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Cranberry
KW  - Drug-Food Interactions
KW  - International Normalized Ratio
KW  - Warfarin -- Adverse Effects
KW  - Aged
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Male
KW  - Warfarin -- Administration and Dosage
SP  - 2113
EP  - 2116
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 65
IS  - 22
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
AB  - PURPOSE: A case of increased International Normalized Ratio (INR) values in a patient receiving warfarin who consumed a large amount of cranberry sauce is reported. SUMMARY: A 75-year-old Caucasian man with atrial fibrillation was taking 22.5 mg of warfarin weekly for 10 months and had maintained stable INR values between 2 and 3. During a clinic visit one week after Thanksgiving, the patient's INR was 4.8. The patient was extensively questioned about any changes in his diet, medications, and health. The patient reported consuming approximately 113 g of cranberry sauce for seven consecutive days before the clinic visit. He reported no other diet or health changes. The patient denied alcohol consumption, had not taken nutritional supplements, and did not miss or double any medication doses during this time period. There were no dosing changes or discernible compliance issues in the 10 months preceding the change in INR. The patient's complete blood cell count and results of a chemistry panel and liver function tests were within normal limits. He did not have any bleeding or bruising. The only identifiable change was the addition of store-bought cranberry sauce to his diet. The patient's warfarin dose was held for two days. Subsequently, the patient resumed warfarin at a dosage of 20 mg per week. Seven days after the patient discontinued the cranberry sauce, his INR returned to 2.2 and remained stable over the next month. CONCLUSION: Consumption of cranberry sauce led to an increase in INR values in a patient receiving warfarin.
SN  - 1079-2082
AD  - Infectious Disease, James J. Peters Veterans Affairs Medical Center, Bronx, NY 10468, USA. kari.mergenhagen2@va.gov
U2  - PMID: 18997138.
DO  - 10.2146/ajhp080135
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 113901648
T1  - Endurance Exercise and the Heart: Friend or Foe?
AU  - Sanchis-Gomar, Fabian
AU  - Pérez, Laura
AU  - Joyner, Michael
AU  - Löllgen, Herbert
AU  - Lucia, Alejandro
Y1  - 2016/04//
N1  - Accession Number: 113901648. Language: English. Entry Date: 20160329. Revision Date: 20160330. Publication Type: Article. Journal Subset: Allied Health; Australia & New Zealand; Peer Reviewed. NLM UID: 8412297. 
KW  - Aerobic Exercises
KW  - Aerobic Exercises -- Adverse Effects
KW  - Heart -- Physiology
KW  - Heart -- Pathology
KW  - Training Effect (Physiology)
KW  - Exercise Intensity
KW  - Exercise Physiology
KW  - Adaptation, Physiological
KW  - Atrial Fibrillation -- Risk Factors
KW  - Running, Distance
KW  - Heart Ventricle, Right -- Physiology
KW  - Heart -- Anatomy and Histology
KW  - Cardiomyopathy, Hypertrophic
KW  - Hypertrophy, Left Ventricular
KW  - Heart Ventricle, Left -- Physiology
KW  - Diagnosis, Cardiovascular
KW  - Magnetic Resonance Imaging
KW  - Dose-Response Relationship
KW  - Death, Sudden, Cardiac
KW  - Male
KW  - Female
KW  - Middle Age
KW  - Aged
KW  - Fibrosis
KW  - Arrhythmia, Ventricular
KW  - Health
KW  - Adult
KW  - Physical Examination, Preparticipation
KW  - Cardiovascular Risk Factors
SP  - 459
EP  - 466
JO  - Sports Medicine
JF  - Sports Medicine
JA  - SPORTS MED
VL  - 46
IS  - 4
PB  - Springer Science & Business Media B.V.
SN  - 0112-1642
AD  - Research Institute Hospital 12 de Octubre ('i+12'), Edificio Actividades Ambulatorias, 6ª Planta, Avda. de Córdoba s/n 28041 Madrid Spain
AD  - Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid Spain
AD  - Department of Anesthesiology, Mayo Clinic, Rochester USA
AD  - European Federation of Sports Medicine Associations (EFSMA) and German Federation of Sports Medicine, Remscheid Germany
DO  - 10.1007/s40279-015-0434-4
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104764773
T1  - Epidemiologic studies of stroke in Shibata, a Japanese provincial city: preliminary report on risk factors for cerebral infarction.
AU  - Tanaka, H
AU  - Hayashi, M
AU  - Date, C
AU  - Imai, K
AU  - Asada, M
AU  - Shoji, H
AU  - Okazaki, K
AU  - Yamamoto, H
AU  - Yoshikawa, K
AU  - Shimada, T
Y1  - 1985/09//1985 Sep-Oct
N1  - Accession Number: 104764773. Language: English. Entry Date: 20110610. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Allied Health; Biomedical; Peer Reviewed; USA. NLM UID: 0235266. 
KW  - Infarction -- Epidemiology
KW  - Cerebrovascular Disorders -- Epidemiology
KW  - Adult
KW  - Aged
KW  - Analysis of Variance
KW  - Blood Pressure
KW  - Body Weight
KW  - Infarction -- Physiopathology
KW  - Cerebrovascular Disorders -- Physiopathology
KW  - Female
KW  - Prospective Studies
KW  - Human
KW  - Japan
KW  - Life Style
KW  - Male
KW  - Middle Age
KW  - Relative Risk
SP  - 773
EP  - 780
JO  - Stroke (00392499)
JF  - Stroke (00392499)
JA  - STROKE
VL  - 16
IS  - 5
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - A 6.5-year prospective study of cerebral infarction among residents 40 years and older was conducted at the Akadani-Ijimino district in Shibata City, Niigata Prefecture, Japan. The response rate for the initial examination was 85% of 1,182 males and 93% of 1,469 females. Nine hundred and sixty males and 1,339 females who were initially free of stroke were followed up from July 1977 through December 1983. Statistically significant risk factors for cerebral infarction appeared to be age, elevated blood pressure, high R, ST-T changes and atrial fibrillation on ECG, and albuminuria. The ECG abnormalities and albuminuria were due to the high blood pressure persisted over a long period of time. The strength of association of blood pressure with cerebral infarction got weak in comparison with other factors, and funduscopic changes which had been regarded as a risk factor for stroke in 1965-1974 did not reach statistical significance because of the spread of the community-based hypertension control. Even in 1977-1983 when Japanese dietary habits were westernized, neither hyperlipidemia nor obesity appeared to be related to the development of cerebral infarction.
SN  - 0039-2499
U2  - PMID: 4049440.
DO  - 10.1161/01.STR.16.5.773
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105603302
T1  - Epidemiology of ischemic and hemorrhagic stroke: incidence, prevalence, mortality, and risk factors.
AU  - Grysiewicz RA
AU  - Thomas K
AU  - Pandey DK
Y1  - 2008/11//2008 Nov
N1  - Accession Number: 105603302. Language: English. Entry Date: 20090403. Revision Date: 20150711. Publication Type: Journal Article; review; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 8219232. 
KW  - Stroke -- Classification
KW  - Stroke -- Epidemiology
KW  - Atrial Fibrillation -- Risk Factors
KW  - Carotid Stenosis
KW  - Diet
KW  - Fatal Outcome
KW  - Inflammation
KW  - Neurology
KW  - Smoking -- Complications
KW  - Stroke -- Mortality
KW  - Stroke -- Risk Factors
SP  - 871
EP  - 895
JO  - Neurologic Clinics
JF  - Neurologic Clinics
JA  - NEUROL CLIN
VL  - 26
IS  - 4
CY  - Philadelphia, Pennsylvania
PB  - W B Saunders
AB  - The epidemiology of ischemic and hemorrhagic stroke is an ongoing exploration to identify risk factors that continue to expand with the advent of technological advancements and preventative medical practices. Identification of risk factors that can or cannot be modified is a crucial step in determining stroke risk. Many of the modifiable risk factors are well established, and specific interventions to reduce stroke risk have been established. Some risk factors are less established, and intervention to reduce risk is yet to be determined by evidence-based medicine. Data from ongoing randomized clinical trials continue to enhance our ability to prevent a first stroke. Copyright © 2009 by Elsevier Inc.
SN  - 0733-8619
AD  - Department of Neurology and Rehabilitation, University of Illinois at Chicago, Chicago, IL 60612, USA.
U2  - PMID: 19026895.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104181029
T1  - EuroHeartCare 2013: bringing professionals together.
AU  - Fitzsimons, Donna
AU  - Dullaghan, Lisa
AU  - Hill, Loreena
Y1  - 2013/05//
N1  - Accession Number: 104181029. Language: English. Entry Date: 20130614. Revision Date: 20150711. Publication Type: Journal Article; pictorial; tables/charts. Journal Subset: Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. 
KW  - Cardiovascular Nursing
KW  - Congresses and Conferences -- United Kingdom
KW  - United Kingdom
KW  - Aged
KW  - Dementia
KW  - Heart Failure -- In Old Age
KW  - Cognition
KW  - Resuscitation
KW  - Defibrillators, Implantable
KW  - Yoga
KW  - Atrial Fibrillation
SP  - 224
EP  - 226
JO  - British Journal of Cardiac Nursing
JF  - British Journal of Cardiac Nursing
JA  - BR J CARD NURS
VL  - 8
IS  - 5
PB  - MA Healthcare Limited
SN  - 1749-6403
AD  - Reader in Nursing, University of Ulster; Senior Manager, Belfast Heath and Social Care Trust, Northern Ireland
AD  - Cardiac Catheterisation Laboratory Manager, Ulster Hospital, Northern Ireland
AD  - Heart Failure Nurse Specialist, Belfast Health and Social Care Trust, Northern Ireland
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 115244802
T1  - Evaluation of pigment location in tinted soft contact lenses.
AU  - Jung, Ji Won
AU  - Han, Sun Hyup
AU  - Kim, Sang ah
AU  - Kim, Eung Kweon
AU  - Seo, Kyoung Yul
AU  - Kim, Tae-im
Y1  - 2016/06//
N1  - Accession Number: 115244802. Language: English. Entry Date: In Process. Revision Date: 20160517. Publication Type: journal article. Journal Subset: Biomedical; Europe; UK & Ireland. NLM UID: 9712714. 
SP  - 210
EP  - 216
JO  - Contact Lens & Anterior Eye
JF  - Contact Lens & Anterior Eye
JA  - CONTACT LENS ANTERIOR EYE
VL  - 39
IS  - 3
CY  - New York, New York
PB  - Elsevier Science
AB  - Purpose: The purpose of this study was to investigate efficient methods to evaluate the pigment layer location of tinted soft contact lenses and to assess various lens products on the market using those methods.Methods: Two types of tinted soft contact lenses with known pigment location embedded or back surface were manufactured and examined. Light microscopy (LM), focused ion beam milling and scanning electron microscopy (FIB-SEM), and Fourier-domain optical coherence tomography (FD-OCT) were used to examine the pigment layer. Lens surface roughness was also measured using atomic force microscopy. In the second part of the experiment, pigment location and surface roughness of a clear lens (Lens A) and eight commercially-available tinted soft contact lenses (Lens B-I) were evaluated using FIB-SEM and FD-OCT.Results: Pigment location could be reliably determined with FIB-SEM and FD-OCT. With LM, 40% of the lens sections were broken or deformed during slide preparation. The pigment particles in Lens B were buried below the front surface and there were no significant differences of roughness between the front and back surfaces. However, all tinted lenses with surface pigment had significant difference of roughness between front and back surfaces at the pigmented area.Conclusion: The FIB-SEM and FD-OCT could reliably locate the pigment layer of tinted soft contact lenses. In addition, lens surface roughness was influenced by pigment layer location.
SN  - 1367-0484
AD  - The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, South Korea
AD  - Department of Ophthalmology and Inha Vision Science Laboratory, Inha University School of Medicine, Incheon, South Korea
AD  - Corneal Dystrophy Research Institute, Severance Biomedical Science Institute, and Brain Korea 21 Plus Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea
U2  - PMID: 26851138.
DO  - 10.1016/j.clae.2016.01.008
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=115244802&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 116237853
T1  - Evaluation of SAMe-TT2R2 score and other clinical factors influencing the quality of anticoagulation therapy in non-valvular atrial fibrillation: a nationwide study in Spain.
AU  - Lobos-Bejarano, José M.
AU  - Barrios, Vivencio
AU  - Polo-García, José
AU  - Escobar, Carlos
AU  - Vargas-Ortega, Diego
AU  - Marín-Montañés, Nuria
AU  - Prieto-Valiente, Luis
AU  - Fuentes, Sonia
AU  - Prieto, Miguel Angel
AU  - García-Ortiz, Luis
AU  - Lobos-Bejarano, José M
AU  - Polo-García, José
AU  - Marín-Montañés, Nuria
AU  - García-Ortiz, Luis
AU  - on behalf the PAULA Study Team
Y1  - 2016/07//
N1  - Accession Number: 116237853. Language: English. Entry Date: In Process. Revision Date: 20160625. Publication Type: Article. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. NLM UID: 0351014. 
SP  - 1201
EP  - 1207
JO  - Current Medical Research & Opinion
JF  - Current Medical Research & Opinion
JA  - CURR MED RES OPIN
VL  - 32
IS  - 7
CY  - Philadelphia, Pennsylvania
PB  - Taylor & Francis Ltd
AB  - Objective: To assess the major clinical factors affecting the quality of anticoagulation and evaluate the predictive value of the SAMe-TT2R2 score to identify patients who will achieve a high average time in therapeutic range (T.T.R.) with vitamin K antagonist (V.K.A.) treatment.Research Design and Methods: This observational, cross-sectional, retrospective and nationwide multicenter study included 1524 patients from the primary care setting with non-valvular atrial fibrillation receiving V.K.A. (≥12 months). We performed a bivariate analysis to identify factors individually associated with the T.T.R. and a multiple regression analysis to identify the independent predictive factors. For the validation of the SAMe-TT2R2 score, the receiver operating characteristic (R.O.C.) curve was calculated and the Hosmer-Lemeshow test was used to test calibration.Results: A total of 94.8% of patients received acenocumarol (4.8% warfarin). A progressive decrease in mean T.T.R. was found when the SAMe-TT2R2 score increased from 0 points (72.1 ± 17.1%) to 4 points (64.1 ± 23.2%), p < 0.001. Other risk scores (CHADS2 and CHA2DS2-VASc, HAS-BLED) were also associated with the mean T.T.R. We found a significant association between low T.T.R. and the following clinical factors: female sex, three or more comorbidities, amiodarone treatment, dietary habits, bleeding history and the intake of ≥7 tablets per day besides V.K.A. (p < 0.01). Regarding SAMe-TT2R2 score validation, the R.O.C. curve showed significant capability, although not high, of discriminating good anticoagulation control (T.T.R. ≥65%) with an area under the curve of 0.562 (95% C.I. 0.533-0.592, p < 0.001) which increased, remaining modest, to 0.594 (95% C.I. 0.564-0.624, p < 0.001) when the factors not included in SAMe-TT2R2 score were added.Conclusion: In this cohort, the SAMe-TT2R2 score had a significant, although modest, ability to assess the likelihood of good international normalized ration (I.N.R.) control, and its predictive value might slightly improve by adding other simple clinical factors. Further research is needed to refine the predictive scales.
SN  - 0300-7995
AD  - Jazmin Primary Care Health Center, East Area Primary Care, Madrid, Spain;
AD  - Cardiology Department, University Hospital Ramon y Cajal, Madrid, Spain;
AD  - Primary Care Health Center Casar de Cáceres, Cáceres, Spain;
AD  - Cardiology Department, University Hospital La Paz, Madrid, Spain;
AD  - High Resolution Hospitalization Unit, Hospital el Toyo, Hospital de Poniente El Ejido, Almeria, Spain;
AD  - Medical Department, Bayer Hispania, Barcelona, Spain;
AD  - Medical Biostatistics, Universidad Católica San Antonio de Murcia, Murcia, Spain;
AD  - Primary Care Health Center, Barcelona, Spain;
AD  - Vallobín-La Florida Primary Care Health Center, Oviedo, Spain;
AD  - Medicine Preventive Department, Oviedo University, Asturias, Spain;
AD  - Unit of Clinical Research La Alamedilla, Salamanca, Spain
AD  - a Jazmin Primary Care Health Center, East Area Primary Care , Madrid , Spain
AD  - c Primary Care Health Center Casar de Cáceres , Cáceres , Spain
AD  - f Medical Department , Bayer Hispania , Barcelona , Spain
AD  - k Unit of Clinical Research La Alamedilla , Salamanca , Spain
U2  - PMID: 26967541.
DO  - 10.1185/03007995.2016.1164676
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108231539
T1  - Evidence in practice.
Y1  - 2009/04//2009 Apr-Jun
N1  - Accession Number: 108231539. Language: English. Entry Date: 20110916. Revision Date: 20150712. Publication Type: Journal Article. Journal Subset: Europe; Nursing; UK & Ireland. NLM UID: 101515974. 
KW  - Adolescence
KW  - Alcohol Drinking
KW  - Aldosterone Antagonists -- Therapeutic Use
KW  - Antihypertensive Agents -- Therapeutic Use
KW  - Atrial Fibrillation -- Risk Factors
KW  - Body Mass Index
KW  - Depression -- Complications
KW  - Diabetes Mellitus, Type 2 -- Risk Factors
KW  - Diabetic Retinopathy -- Risk Factors -- In Adolescence
KW  - Exercise -- In Middle Age
KW  - Health Behavior
KW  - Health Promotion
KW  - Heart Failure -- Prevention and Control
KW  - Hypertension -- Complications -- In Adolescence
KW  - Longevity
KW  - Middle Age
KW  - Mortality -- Risk Factors
KW  - Myocardial Infarction -- Mortality
KW  - Myocardial Infarction -- Risk Factors
KW  - Risk Assessment -- Methods
KW  - Sex Factors
KW  - Ventricular Dysfunction, Left -- Mortality
KW  - Women's Health
SP  - 49
EP  - 52
JO  - British Journal of Primary Care Nursing: Cardiovascular Disease, Diabetes & Kidney Care
JF  - British Journal of Primary Care Nursing: Cardiovascular Disease, Diabetes & Kidney Care
JA  - BR J PRIM CARE NURS
VL  - 6
IS  - 2
PB  - Sherborne Gibbs Limited
SN  - 2040-7475
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108231539&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108231885
T1  - Evidence in practice.
Y1  - 2009/10//2009 Oct-Dec
N1  - Accession Number: 108231885. Language: English. Entry Date: 20110930. Revision Date: 20150712. Publication Type: Journal Article; pictorial. Journal Subset: Europe; Nursing; UK & Ireland. Special Interest: Evidence-Based Practice. NLM UID: 101515974. 
KW  - Angina Pectoris -- Therapy
KW  - Atrial Fibrillation
KW  - Atrial Fibrillation -- Risk Factors
KW  - Cardiology
KW  - Cardiovascular Diseases
KW  - Clopidogrel Bisulfate -- Therapeutic Use
KW  - Congresses and Conferences -- Spain
KW  - Exercise
KW  - Harm Reduction
KW  - Health Status
KW  - Influenza
KW  - Influenza Vaccine
KW  - Medication Compliance
KW  - Myocardial Infarction -- Risk Factors
KW  - Nursing Practice, Evidence-Based
KW  - Polypharmacy
KW  - Stroke -- Prevention and Control
KW  - Stroke -- Risk Factors
KW  - Surgery, Operative -- Adverse Effects
SP  - 157
EP  - 160
JO  - British Journal of Primary Care Nursing: Cardiovascular Disease, Diabetes & Kidney Care
JF  - British Journal of Primary Care Nursing: Cardiovascular Disease, Diabetes & Kidney Care
JA  - BR J PRIM CARE NURS
VL  - 6
IS  - 4
PB  - Sherborne Gibbs Limited
SN  - 2040-7475
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108231885&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108231253
T1  - Evidence in practice.
Y1  - 2007/09//2007 Sep-Oct
N1  - Accession Number: 108231253. Language: English. Entry Date: 20110826. Revision Date: 20150712. Publication Type: Journal Article; pictorial. Journal Subset: Europe; Nursing; UK & Ireland. NLM UID: 101515974. 
KW  - Atrial Fibrillation -- Diagnosis
KW  - Carbonated Beverages -- Adverse Effects
KW  - Cardiovascular Risk Factors
KW  - Coronary Disease -- Mortality
KW  - Counseling
KW  - Diabetes Mellitus -- Mortality
KW  - Diabetic Diet
KW  - Drug-Eluting Stents
KW  - Glycemic Index
KW  - Metformin -- Therapeutic Use
KW  - Obesity
KW  - Peripheral Vascular Diseases -- Drug Therapy
KW  - Risk Assessment
KW  - Wound Care
SP  - 211
EP  - 219
JO  - British Journal of Primary Care Nursing: Cardiovascular Disease, Diabetes & Kidney Care
JF  - British Journal of Primary Care Nursing: Cardiovascular Disease, Diabetes & Kidney Care
JA  - BR J PRIM CARE NURS
VL  - 4
IS  - 5
PB  - Sherborne Gibbs Limited
SN  - 2040-7475
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108231253&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108231179
T1  - Evidence in practice.
Y1  - 2006/09//2006 Sep-Oct
N1  - Accession Number: 108231179. Language: English. Entry Date: 20110909. Revision Date: 20150712. Publication Type: Journal Article; pictorial; tables/charts. Journal Subset: Europe; Nursing; UK & Ireland. NLM UID: 101515974. 
KW  - Analgesics -- Adverse Effects
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Cardiovascular Diseases -- Symptoms
KW  - Cardiovascular Risk Factors
KW  - Chest Pain
KW  - Diabetes Mellitus -- Complications
KW  - Diet
KW  - Glycemic Index
KW  - Life Expectancy
KW  - Migraine -- Epidemiology
KW  - Physical Activity
KW  - Thrombosis -- Risk Factors
SP  - 207
EP  - 214
JO  - British Journal of Primary Care Nursing: Cardiovascular Disease, Diabetes & Kidney Care
JF  - British Journal of Primary Care Nursing: Cardiovascular Disease, Diabetes & Kidney Care
JA  - BR J PRIM CARE NURS
VL  - 3
IS  - 5
PB  - Sherborne Gibbs Limited
SN  - 2040-7475
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108231179&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108231170
T1  - Evidence in practice.
Y1  - 2006/07//2006 Jul-Aug
N1  - Accession Number: 108231170. Language: English. Entry Date: 20110909. Revision Date: 20150712. Publication Type: Journal Article; pictorial. Journal Subset: Europe; Nursing; UK & Ireland. NLM UID: 101515974. 
KW  - Antidepressive Agents -- Administration and Dosage
KW  - Antihypertensive Agents -- Adverse Effects
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Cardiovascular Diseases
KW  - Diabetes Mellitus -- Drug Therapy
KW  - Diabetes Mellitus, Type 2 -- Risk Factors
KW  - Dietary Proteins -- Therapeutic Use
KW  - Glycemic Control
KW  - Hypoglycemic Agents
KW  - Insulin
KW  - Warfarin
KW  - Weight Control
SP  - 159
EP  - 165
JO  - British Journal of Primary Care Nursing: Cardiovascular Disease, Diabetes & Kidney Care
JF  - British Journal of Primary Care Nursing: Cardiovascular Disease, Diabetes & Kidney Care
JA  - BR J PRIM CARE NURS
VL  - 3
IS  - 4
PB  - Sherborne Gibbs Limited
SN  - 2040-7475
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108231170&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103966679
T1  - Evidence-Based Medicine.
AU  - Ehrlich, Alan
Y1  - 2014/06//
N1  - Accession Number: 103966679. Language: English. Entry Date: 20140627. Revision Date: 20150710. Publication Type: Journal Article; diagnostic images; pictorial. Journal Subset: Nursing; USA. Special Interest: Advanced Nursing Practice; Evidence-Based Practice. NLM UID: 9804511. 
KW  - Anxiety Disorders -- Therapy -- In Infancy and Childhood
KW  - Cognitive Therapy -- In Infancy and Childhood
KW  - Glucose Intolerance -- Therapy
KW  - Cardiovascular Risk Factors
KW  - Walking
KW  - Arteriovenous Malformations -- Radiography
KW  - Antibiotic Prophylaxis
KW  - Pulmonary Disease, Chronic Obstructive -- Drug Therapy
KW  - Disease Exacerbation -- Prevention and Control
KW  - Azithromycin -- Adverse Effects
KW  - Hearing Disorders -- Chemically Induced
KW  - Dialysis Patients
KW  - Atrial Fibrillation -- Drug Therapy -- In Old Age
KW  - Warfarin -- Adverse Effects
KW  - Aged
KW  - Hemorrhage -- Risk Factors
KW  - Stroke -- Risk Factors
KW  - Kidney Failure, Chronic
KW  - Child
SP  - 126
EP  - 129
JO  - Clinical Advisor
JF  - Clinical Advisor
JA  - CLIN ADVIS
VL  - 17
IS  - 6
CY  - New York, New York
PB  - Haymarket Media, Inc.
SN  - 1524-7317
AD  - Assistant Clinical Professor, Family Medicine, University of Massachusetts Medical School, Worcester
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103966679&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 116618013
T1  - Exercise and Arrhythmias: A Double-Edged Sword.
AU  - MANOLIS, ANTONIS S.
AU  - MANOLIS, ANTONIS A.
Y1  - 2016/07//
N1  - Accession Number: 116618013. Language: English. Entry Date: 20160711. Revision Date: 20160711. Publication Type: Article. Journal Subset: Allied Health; Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7803944. 
KW  - Exercise -- Adverse Effects
KW  - Atrial Fibrillation
KW  - Tachycardia, Ventricular
KW  - Athletes
KW  - Death, Sudden, Cardiac
KW  - Health Screening
SP  - 748
EP  - 762
JO  - Pacing & Clinical Electrophysiology
JF  - Pacing & Clinical Electrophysiology
JA  - PACING CLIN ELECTROPHYSIOL
VL  - 39
IS  - 7
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 0147-8389
AD  - Third Department of Cardiology, Athens University School of Medicine
DO  - 10.1111/pace.12879
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=116618013&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105109955
T1  - Exercise Pulmonary Hypertension in MR.
AU  - Crawford MH
Y1  - 2010/09//
N1  - Accession Number: 105109955. Language: English. Entry Date: 20101006. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9880022. 
KW  - Hypertension, Pulmonary -- Epidemiology
KW  - Mitral Valve Insufficiency -- Complications
KW  - Exercise
KW  - Mitral Valve Insufficiency -- Physiopathology
KW  - Echocardiography
KW  - Hypertension, Pulmonary -- Etiology
KW  - Hypertension, Pulmonary -- Mortality
KW  - Hypertension, Pulmonary -- Physiopathology
SP  - 70
EP  - 71
JO  - Clinical Cardiology Alert
JF  - Clinical Cardiology Alert
JA  - CLIN CARDIOL ALERT
VL  - 29
IS  - 9
CY  - Atlanta, Georgia
PB  - AHC Media LLC
AB  - CURRENT GUIDELINES RECOMMEND MITRAL-VALVE SURGERY for severe organic mitral regurgitation in asymptomatic patients if exercise pulmonary hypertension (PASP > 60 mmHg) is demonstrated. However, little is known about the echocardiographic correlates of exercise-induced pulmonary hypertension (PH) or its relationship to symptom-free survival. Thus, these investigators from Belgium studied 78 consecutive asymptomatic patients with moderate or more organic mitral regurgitation (MR) and preserved left ventricular (LV) systolic function, who were referred for exercise echocardiographic testing. Patients with ischemic heart disease, valve stenosis, or concomitant regurgitation, atrial fibrillation, or poor images, were excluded (n = 10). Semi-supine bicycle exercise, with two-minute stages increased by 25W at each stage, was performed with echo Doppler imaging. The results of the exercise study were not shared with the referring physician. Mean follow-up was 19 months (2-56) in 100% of the patients. Resting PH was present in 15% (PASP > 50) and 46% exhibited exercise PH. Multivariate analysis showed that only E/Ea correlated with resting systolic pulmonary artery pressure (SPAP) and measures of MR severity did not. Exercise PH was correlated with age, resting SPAP, and exercise MR severity measures. During follow-up, resting and exercise PH were associated with decreased symptom-free survival over two years compared to medically treated patients (36 vs. 59%, p = 0.04; 35% vs. 75%, p < .0001, respectively). After adjustment for age and sex, resting PH was no longer predictive (HR = 2.1, 95% CI 0.9-4.9, p = 0.08). Exercise PH remained predictive (HR = 2.8, 1.4-5.4, p = 0.002). Receiver operating curve (ROC) analysis showed that the best cut point for predicting reduced symptom-free survival was an exercise SPAP > 56 mmHg (specifically 73%, sensitively 82%, positive predictive value 72%, and negative predictive value 80%). Mitral-valve surgery was performed in 25 patients during follow-up (20 repairs and five replacements) because of symptoms. The authors concluded that an exercise SPAP > 56 mmHg predicts the occurrence of symptoms and is associated with a significantly lower symptom-free survival.
SN  - 0741-4218
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105109249
T1  - Exercise Pulmonary Hypertension in MR.
AU  - Crawford MH
Y1  - 2010/09/03/Sep2010 Pharmacology
N1  - Accession Number: 105109249. Language: English. Entry Date: 20101109. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Supplement Title: Sep2010 Pharmacology. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9880022. 
KW  - Hypertension, Pulmonary -- Epidemiology
KW  - Mitral Valve Insufficiency -- Complications
KW  - Blood Pressure
KW  - Hypertension, Pulmonary -- Etiology
KW  - Hypertension, Pulmonary -- Mortality
KW  - Mitral Valve Insufficiency -- Physiopathology
KW  - Systole -- Physiology
SP  - 70
EP  - 71
JO  - Clinical Cardiology Alert
JF  - Clinical Cardiology Alert
JA  - CLIN CARDIOL ALERT
CY  - Atlanta, Georgia
PB  - AHC Media LLC
AB  - CURRENT GUIDELINES RECOMMEND MITRAL-VALVE SURGERY for severe organic mitral regurgitation in asymptomatic patients if exercise pulmonary hypertension (PASP > 60 mmHg) is demonstrated. However, little is known about the echocardiographic correlates of exercise-induced pulmonary hypertension (PH) or its relationship to symptom-free survival. Thus, these investigators from Belgium studied 78 consecutive asymptomatic patients with moderate or more organic mitral regurgitation (MR) and preserved left ventricular (LV) systolic function, who were referred for exercise echocardiographic testing. Patients with ischemic heart disease, valve stenosis, or concomitant regurgitation, atrial fibrillation, or poor images, were excluded (n = 10). Semi-supine bicycle exercise, with two-minute stages increased by 25W at each stage, was performed with echo Doppler imaging. The results of the exercise study were not shared with the referring physician. Mean follow-up was 19 months (2-56) in 100% of the patients. Resting PH was present in 15% (PASP > 50) and 46% exhibited exercise PH. Multivariate analysis showed that only E/Ea correlated with resting systolic pulmonary artery pressure (SPAP) and measures of MR severity did not. Exercise PH was correlated with age, resting SPAP, and exercise MR severity measures. During follow-up, resting and exercise PH were associated with decreased symptom-free survival over two years compared to medically treated patients (36 vs. 59%, p = 0.04; 35% vs. 75%, p < .0001, respectively). After adjustment for age and sex, resting PH was no longer predictive (HR = 2.1, 95% CI 0.9-4.9, p = 0.08). Exercise PH remained predictive (HR = 2.8, 1.4-5.4, p = 0.002). Receiver operating curve (ROC) analysis showed that the best cut point for predicting reduced symptom-free survival was an exercise SPAP > 56 mmHg (specifically 73%, sensitively 82%, positive predictive value 72%, and negative predictive value 80%). Mitral-valve surgery was performed in 25 patients during follow-up (20 repairs and five replacements) because of symptoms. The authors concluded that an exercise SPAP > 56 mmHg predicts the occurrence of symptoms and is associated with a significantly lower symptom-free survival.
SN  - 0741-4218
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105109249&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106038921
T1  - Exercise response of the recipient atrial remnant after orthotopic cardiac transplantation: implications for recipient atrial triggered pacing.
AU  - Bolt ND
AU  - Brady S
AU  - Dark JH
AU  - Mccomb JM
Y1  - 1998/11/15/
N1  - Accession Number: 106038921. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Allied Health; Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7803944. 
SP  - 2331
EP  - 2337
JO  - Pacing & Clinical Electrophysiology
JF  - Pacing & Clinical Electrophysiology
JA  - PACING CLIN ELECTROPHYSIOL
VL  - 21
IS  - 11P2
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - The assumption that the recipient atrial remnant in the cardiac transplant recipient is normal has led to the suggestion that it is an appropriate trigger for permanent pacing in transplant recipients who need pacing or to restore chronotropic competence and/or mechanical synchrony of the composite atrium. We examined the chronotropic response to exercise in 12 orthotopic cardiac transplant recipients (mean age 49 years) at a mean time of 17 months posttransplantation. Recipient and donor atrial rates were noted and compared and chronotropic competence determined. Two of 12 recipient atrial remnants were in atrial fibrillation. Only six of the remaining 10 recipient atria exhibited chronotropic competence. Seven of 10 recipient atria had rates higher than that of the donor. Only four often recipient atria in sinus rhythm satisfied both criteria. Two of these had abnormally high atrial responses early into exercise. Of the remaining two, only one recipient atrial remnant demonstrated a >= 20% increase in heart rate above that of the donor at peak exercise. Hence only 1 of 12 (8.3%) transplant recipients potentially could benefit from recipient atrial triggered pacing. While recipient atrial triggered pacing is an attractive theoretical concept for restoring chronotropic competence following orthotopic cardiac transplantation, it may rarely be practical because the recipient atrial remnant displays rhythm abnormalities, chronotropic incompetence, and abnormalities in its exercise response.
SN  - 0147-8389
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103967587
T1  - Extravirgin Olive Oil Consumption Reduces Risk of Atrial Fibrillation: The PREDIMED (Prevención con Dieta Mediterránea) Trial.
AU  - Martínez-González, Miguel A
AU  - Toledo, Estefanía
AU  - Arós, Fernando
AU  - Fiol, Miquel
AU  - Corella, Dolores
AU  - Salas-Salvadó, Jordi
AU  - Ros, Emilio
AU  - Covas, Maria I
AU  - Fernández-Crehuet, Joaquín
AU  - Lapetra, José
AU  - Muñoz, Miguel A
AU  - Fitó, Monserrat
AU  - Serra-Majem, Luis
AU  - Pintó, Xavier
AU  - Lamuela-Raventós, Rosa M
AU  - Sorlí, Jose V
AU  - Babio, Nancy
AU  - Buil-Cosiales, Pilar
AU  - Ruiz-Gutierrez, Valentina
AU  - Estruch, Ramón
Y1  - 2014/07//7/1/2014
N1  - Accession Number: 103967587. Corporate Author: PREDIMED Investigators*. Language: English. Entry Date: 20140919. Revision Date: 20150710. Publication Type: Journal Article; research; randomized controlled trial. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0147763. 
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Mediterranean Diet
KW  - Dietary Fats -- Therapeutic Use
KW  - Plant Oils
KW  - Aged
KW  - Atrial Fibrillation -- Epidemiology
KW  - Atrial Fibrillation -- Metabolism
KW  - Diet, Fat-Restricted
KW  - Female
KW  - Prospective Studies
KW  - Human
KW  - Incidence
KW  - Inflammation
KW  - Experimental Studies
KW  - Male
KW  - Middle Age
KW  - Nuts
KW  - Oxidative Stress
KW  - Cox Proportional Hazards Model
KW  - Relative Risk
KW  - Risk Factors
KW  - Spain
KW  - Stroke -- Epidemiology
KW  - Stroke -- Prevention and Control
KW  - Treatment Outcomes
SP  - 18
EP  - 26
JO  - Circulation
JF  - Circulation
JA  - CIRCULATION
VL  - 130
IS  - 1
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - BACKGROUND: The PREDIMED (Prevención con Dieta Mediterránea) randomized primary prevention trial showed that a Mediterranean diet enriched with either extravirgin olive oil or mixed nuts reduces the incidence of stroke, myocardial infarction, and cardiovascular mortality. We assessed the effect of these diets on the incidence of atrial fibrillation in the PREDIMED trial. METHODS AND RESULTS: Participants were randomly assigned to 1 of 3 diets: Mediterranean diet supplemented with extravirgin olive oil, Mediterranean diet supplemented with mixed nuts, or advice to follow a low-fat diet (control group). Incident atrial fibrillation was adjudicated during follow-up by an events committee blinded to dietary group allocation. Among 6705 participants without prevalent atrial fibrillation at randomization, we observed 72 new cases of atrial fibrillation in the Mediterranean diet with extravirgin olive oil group, 82 in the Mediterranean diet with mixed nuts group, and 92 in the control group after median follow-up of 4.7 years. The Mediterranean diet with extravirgin olive oil significantly reduced the risk of atrial fibrillation (hazard ratio, 0.62; 95% confidence interval, 0.45-0.85 compared with the control group). No effect was found for the Mediterranean diet with nuts (hazard ratio, 0.89; 95% confidence interval, 0.65-1.20). CONCLUSIONS: In the absence of proven interventions for the primary prevention of atrial fibrillation, this post hoc analysis of the PREDIMED trial suggests that extravirgin olive oil in the context of a Mediterranean dietary pattern may reduce the risk of atrial fibrillation. CLINICAL TRIAL REGISTRATION URL: http://www.controlled-trials.com. Unique identifier: ISRCTN35739639.
SN  - 0009-7322
U2  - PMID: 24787471.
DO  - 10.1161/CIRCULATIONAHA.113.006921
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103967587&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107277463
T1  - Factors contributing to the hospitalization of patients with congestive heart failure.
AU  - Chin MH
AU  - Goldman L
Y1  - 1997/04//
N1  - Accession Number: 107277463. Language: English. Entry Date: 19980801. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Core Nursing; Double Blind Peer Reviewed; Nursing; Peer Reviewed; Public Health; USA. Instrumentation: Charlson Comorbidity Index. Grant Information: Supported by National Institutes of Health/National Institute on Aging Geriatric Academic Program Award 5-K12-AG-00488. NLM UID: 1254074. 
KW  - Hospitalization
KW  - Heart Failure -- Symptoms
KW  - Angiotensin-Converting Enzyme Inhibitors -- Therapeutic Use
KW  - Drug Utilization
KW  - Prospective Studies
KW  - Convenience Sample
KW  - Record Review
KW  - Health Status Indicators
KW  - Reproducibility of Results
KW  - Fisher's Exact Test
KW  - Chi Square Test
KW  - Logistic Regression
KW  - P-Value
KW  - Risk Factors
KW  - Academic Medical Centers
KW  - Heart Failure -- Etiology
KW  - Whites
KW  - Blacks
KW  - Ventricular Ejection Fraction
KW  - Two-Tailed Test
KW  - Hypertension -- Complications
KW  - Myocardial Ischemia -- Complications
KW  - Middle Age
KW  - Aged
KW  - Aged, 80 and Over
KW  - Inpatients
KW  - Male
KW  - Female
KW  - Angina Pectoris -- Complications
KW  - Bivariate Statistics
KW  - Odds Ratio
KW  - Confidence Intervals
KW  - Heart Failure -- Drug Therapy
KW  - Patient Compliance
KW  - Funding Source
KW  - Human
SP  - 643
EP  - 648
JO  - American Journal of Public Health
JF  - American Journal of Public Health
JA  - AM J PUBLIC HEALTH
VL  - 87
IS  - 4
CY  - Washington, District of Columbia
PB  - American Public Health Association
AB  - OBJECTIVES: This study identifies acute precipitants of hospitalization and evaluates utilization of angiotension-converting enzyme inhibitors in patients admitted with congestive heart failure. METHODS: Cross-sectional chart-review study was done of 435 patients admitted nonelectively from February 1993 to February 1994 to an urban university hospital with a complaint of shortness of breath or fatigue and evidence of congestive heart failure. RESULTS: The most common identifiable abnormalities associated with clinical deterioration prior to admission were acute anginal chest pain (33%), respiratory infection (16%), uncontrolled hypertension with initial systolic blood pressure > or = 180 mm Hg (15%), atrial arrhythmia with heart rate > or = 120 (8%), and noncompliance with medications (15%) or diet (6%); in 34% of patients, no clear cause could be identified. After exclusion of those who were already on a different vasodilator or who had relative contraindications, 18 (32%) of the patients with ejection fractions < or = 0.35 measured prior to admission were not taking an angiotensin-converting enzyme inhibitor on presentation to the hospital. CONCLUSIONS: Interventions to improve compliance, the control of hypertension, and the appropriate use of angiotensin-converting enzyme inhibitors may prevent many hospitalizations of heart-failure patients.
SN  - 0090-0036
AD  - Research from: Dept of Medicine, Brigham and Women's Hospital, Boston, MA
U2  - PMID: 9146445.
DO  - 10.2105/AJPH.87.4.643
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107277463&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106519640
T1  - Fish intake and risk of incident atrial fibrillation.
AU  - Mozaffarian D
AU  - Psaty BM
AU  - Rimm EB
AU  - Lemaitre RN
AU  - Burke GL
AU  - Lyles MF
AU  - Lefkowitz D
AU  - Siscovick DS
Y1  - 2004/07/27/2004 Jul 27
N1  - Accession Number: 106519640. Language: English. Entry Date: 20050930. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Grant Information: Contracts N01-HC-85079 through N01-HC-85086, N01-HC-35129, and N01-HC-15103 from the National Heart, Lung, and Blood Institute; also supported in part by a National Research Service Award Training Grant in Academic Nutrition (DK07703). NLM UID: 0147763. 
KW  - Atrial Fibrillation -- Risk Factors -- In Old Age
KW  - Fish
KW  - Nutritional Assessment
KW  - Nutritional Status
KW  - Aged
KW  - Aged, 80 and Over
KW  - Data Analysis, Statistical
KW  - Descriptive Statistics
KW  - Female
KW  - Funding Source
KW  - Incidence
KW  - Male
KW  - Prospective Studies
KW  - Human
SP  - 368
EP  - 373
JO  - Circulation
JF  - Circulation
JA  - CIRCULATION
VL  - 110
IS  - 4
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - BACKGROUND: Atrial fibrillation (AF) is the most common arrhythmia in clinical practice and is particularly common in the elderly. Although effects of fish intake, including potential antiarrhythmic effects, may favorably influence risk of AF, relationships between fish intake and AF incidence have not been evaluated. METHODS AND RESULTS: In a prospective, population-based cohort of 4815 adults > or =age 65 years, usual dietary intake was assessed at baseline in 1989 and 1990. Consumption of tuna and other broiled or baked fish correlated with plasma phospholipid long-chain n-3 fatty acids, whereas consumption of fried fish or fish sandwiches (fish burgers) did not. AF incidence was prospectively ascertained on the basis of hospital discharge records and annual electrocardiograms. During 12 years' follow-up, 980 cases of incident AF were diagnosed. In multivariate analyses, consumption of tuna or other broiled or baked fish was inversely associated with incidence of AF, with 28% lower risk with intake 1 to 4 times per week (HR=0.72, 95% CI=0.58 to 0.91, P=0.005), and 31% lower risk with intake > or =5 times per week (HR=0.69, 95% CI=0.52 to 0.91, P=0.008), compared with <1 time per month (P trend=0.004). Results were not materially different after adjustment for preceding myocardial infarction or congestive heart failure. In similar analyses, fried fish/fish sandwich consumption was not associated with lower risk of AF. CONCLUSIONS: Among elderly adults, consumption of tuna or other broiled or baked fish, but not fried fish or fish sandwiches, is associated with lower incidence of AF. Fish intake may influence risk of this common cardiac arrhythmia.
SN  - 0009-7322
AD  - Channing Laboratory, Brigham and Women's Hospital and Harvard Medical School, and Departments of Epidemiology and Nutrition, Harvard School of Public Health, Boston, MA 02115; darymd@hotmail.com
U2  - PMID: 15262826.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106519640&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107924674
T1  - Fish Out of Water.
AU  - Firnhaber, Jonathon M.
AU  - Kolasa, Kathryn M.
Y1  - 2013/11//Nov/Dec2013
N1  - Accession Number: 107924674. Language: English. Entry Date: 20131219. Revision Date: 20150820. Publication Type: Journal Article; case study. Journal Subset: Allied Health; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Nutrition. NLM UID: 0055201. 
KW  - Fish Oils -- Administration and Dosage
KW  - Dietary Supplementation
KW  - Fish
KW  - Diet
KW  - Heart Diseases -- Prevention and Control
KW  - Mortality -- Prevention and Control
KW  - Triglycerides -- Blood
KW  - Hypercholesterolemia -- Prevention and Control
KW  - Fatty Acids, Omega-3
KW  - Male
KW  - Middle Age
KW  - Cardiovascular Diseases -- Mortality
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Cerebrovascular Disorders -- Prevention and Control
KW  - Heart Failure -- Prevention and Control
KW  - Female
KW  - Adult
KW  - Hypercholesterolemia -- Diet Therapy
SP  - 245
EP  - 250
JO  - Nutrition Today
JF  - Nutrition Today
JA  - NUTR TODAY
VL  - 48
IS  - 6
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - We present 2 cases from our primary care clinic where patients posed questions about the use of fish oil supplements and eating fish meals to reduce risks for heart disease and premature death and for lowering elevated triglyceride levels. A brief summary of the relevant but often conflicting literature is provided as background for the recommendations given to the patients.
SN  - 0029-666X
AD  - Director, Family Medicine Residency Program at East Carolina University, Greenville, North Carolina
AD  - Professor Emeritus in Family Medicine and in Pediatrics, East Carolina University Medicine, Greenville, North Carolina
DO  - 10.1097/NT.0000000000000003
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107924674&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104647388
T1  - Follow-up.
Y1  - 2011/07//
N1  - Accession Number: 104647388. Language: English. Entry Date: 20110629. Revision Date: 20150711. Publication Type: Journal Article; brief item. Journal Subset: Biomedical; USA. NLM UID: 9425723. 
KW  - Rehabilitation, Cardiac
KW  - Yoga
KW  - Atrial Fibrillation -- Therapy
SP  - 6
EP  - 6
JO  - Harvard Heart Letter
JF  - Harvard Heart Letter
JA  - HARV HEART LETT
VL  - 21
IS  - 11
CY  - Stamford, Connecticut
PB  - Harvard Health Publications
SN  - 1051-5313
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104647388&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104892302
T1  - For your health.
Y1  - 2011/05//2011 May-Jun
N1  - Accession Number: 104892302. Language: English. Entry Date: 20110715. Revision Date: 20150711. Publication Type: Journal Article; pictorial. Journal Subset: Allied Health; USA. NLM UID: 101167420. 
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Diet
KW  - Fish
KW  - Food
KW  - Games
KW  - Prostatic Neoplasms -- Prevention and Control
KW  - Vitamin D -- Therapeutic Use
KW  - Weight Loss
SP  - 20
EP  - 21
JO  - CMA Today
JF  - CMA Today
JA  - CMA TODAY
VL  - 44
IS  - 3
CY  - Chicago, Illinois
PB  - American Association of Medical Assistants
SN  - 1543-2998
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104892302&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104592945
T1  - Gender differences of atrial and ventricular remodeling and autonomic tone in nonelite athletes.
AU  - Wilhelm M
AU  - Roten L
AU  - Tanner H
AU  - Wilhelm I
AU  - Schmid JP
AU  - Saner H
Y1  - 2011/11/15/
N1  - Accession Number: 104592945. Language: English. Entry Date: 20120323. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0207277. 
KW  - Athletes
KW  - Heart Atrium -- Physiopathology
KW  - Cardiovascular System Physiology
KW  - Adult
KW  - Atrial Fibrillation -- Physiopathology
KW  - Blood Flow Velocity -- Physiology
KW  - Blood Pressure -- Physiology
KW  - Diastole -- Physiology
KW  - Electrocardiography
KW  - Female
KW  - Heart Atrium -- Ultrasonography
KW  - Heart Rate -- Physiology
KW  - Heart Ventricle -- Ultrasonography
KW  - Male
KW  - Relaxation -- Physiology
KW  - Sex Factors
KW  - Systole -- Physiology
SP  - 1489
EP  - 1495
JO  - American Journal of Cardiology
JF  - American Journal of Cardiology
JA  - AM J CARDIOL
VL  - 108
IS  - 10
CY  - Philadelphia, Pennsylvania
PB  - Elsevier Inc.
SN  - 0002-9149
AD  - Division of Cardiovascular Prevention, Rehabilitation, and Sports Cardiology, Department of Cardiology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
U2  - PMID: 21864814.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104592945&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 110433906
T1  - Getting more fit improves outcomes.
Y1  - 2015/11//
N1  - Accession Number: 110433906. Language: English. Entry Date: 20151021. Revision Date: 20160511. Publication Type: Article. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. NLM UID: 7600137. 
KW  - Atrial Fibrillation -- Rehabilitation
KW  - Obesity -- Therapy
KW  - Cardiac Patients
KW  - Weight Reduction Programs
KW  - Therapeutic Exercise
KW  - Physical Fitness
KW  - Outcomes (Health Care)
KW  - Comorbidity
KW  - Body Mass Index
KW  - Prospective Studies
KW  - Recurrence
KW  - Energy Metabolism
KW  - Combined Modality Therapy
SP  - 23
EP  - 23
JO  - Nursing
JF  - Nursing
JA  - NURSING
VL  - 45
IS  - 11
CY  - Philadelphia, Pennsylvania
PB  - Springhouse Corporation
SN  - 0360-4039
DO  - 10.1097/01.NURSE.0000472569.61223.c5
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=110433906&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104823398
T1  - Guidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.
AU  - Goldstein LB
AU  - Bushnell CD
AU  - Adams RJ
AU  - Appel LJ
AU  - Braun LT
AU  - Chaturvedi S
AU  - Creager MA
AU  - Culebras A
AU  - Eckel RH
AU  - Hart RG
AU  - Hinchey JA
AU  - Howard VJ
AU  - Jauch EC
AU  - Levine SR
AU  - Meschia JF
AU  - Moore WS
AU  - Nixon JV
AU  - Pearson TA
Y1  - 2011/02//
N1  - Accession Number: 104823398. Corporate Author: American Heart Association Stroke Council. Language: English. Entry Date: 20110318. Revision Date: 20150711. Publication Type: Journal Article; practice guidelines. Journal Subset: Allied Health; Biomedical; Peer Reviewed; USA. Special Interest: Evidence-Based Practice; Physical Therapy. NLM UID: 0235266. 
KW  - American Heart Association
KW  - Health Personnel
KW  - Preventive Health Care -- Standards
KW  - Stroke -- Prevention and Control
KW  - Medical Practice, Evidence-Based -- Methods
KW  - Medical Practice, Evidence-Based -- Standards
KW  - Preventive Health Care -- Methods
KW  - Risk Factors
KW  - Stroke -- Diagnosis
KW  - United States
SP  - 517
EP  - 584
JO  - Stroke (00392499)
JF  - Stroke (00392499)
JA  - STROKE
VL  - 42
IS  - 2
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - BACKGROUND AND PURPOSE: This guideline provides an overview of the evidence on established and emerging risk factors for stroke to provide evidence-based recommendations for the reduction of risk of a first stroke. METHODS: Writing group members were nominated by the committee chair on the basis of their previous work in relevant topic areas and were approved by the American Heart Association (AHA) Stroke Council Scientific Statement Oversight Committee and the AHA Manuscript Oversight Committee. The writing group used systematic literature reviews (covering the time since the last review was published in 2006 up to April 2009), reference to previously published guidelines, personal files, and expert opinion to summarize existing evidence, indicate gaps in current knowledge, and when appropriate, formulate recommendations using standard AHA criteria (Tables 1 and 2). All members of the writing group had the opportunity to comment on the recommendations and approved the final version of this document. The guideline underwent extensive peer review by the Stroke Council leadership and the AHA scientific statements oversight committees before consideration and approval by the AHA Science Advisory and Coordinating Committee. RESULTS: Schemes for assessing a person's risk of a first stroke were evaluated. Risk factors or risk markers for a first stroke were classified according to potential for modification (nonmodifiable, modifiable, or potentially modifiable) and strength of evidence (well documented or less well documented). Nonmodifiable risk factors include age, sex, low birth weight, race/ethnicity, and genetic predisposition. Well-documented and modifiable risk factors include hypertension, exposure to cigarette smoke, diabetes, atrial fibrillation and certain other cardiac conditions, dyslipidemia, carotid artery stenosis, sickle cell disease, postmenopausal hormone therapy, poor diet, physical inactivity, and obesity and body fat distribution. Less well-documented or potentially modifiable risk factors include the metabolic syndrome, excessive alcohol consumption, drug abuse, use of oral contraceptives, sleep-disordered breathing, migraine, hyperhomocysteinemia, elevated lipoprotein(a), hypercoagulability, inflammation, and infection. Data on the use of aspirin for primary stroke prevention are reviewed. CONCLUSIONS: Extensive evidence identifies a variety of specific factors that increase the risk of a first stroke and that provide strategies for reducing that risk.
SN  - 0039-2499
U2  - PMID: 21127304.
DO  - 10.1161/STR.0b013e3181fcb238
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107898933
T1  - Habitual Caffeine Consumption Does Not Increase Risk of Atrial Fibrillation.
Y1  - 2014/04//
N1  - Accession Number: 107898933. Language: English. Entry Date: 20140407. Revision Date: 20150712. Publication Type: Journal Article; abstract; pictorial. Journal Subset: Consumer Health; USA. Special Interest: Consumer Health; Nutrition; Public Health. NLM UID: 9705861. 
KW  - Atrial Fibrillation
KW  - Diet
KW  - Caffeine
KW  - Coffee
KW  - Tea
SP  - 1
EP  - 3
JO  - Tufts University Health & Nutrition Letter
JF  - Tufts University Health & Nutrition Letter
JA  - TUFTS UNIV HEALTH NUTR LETT
VL  - 32
IS  - 2
CY  - Medford, Massachusetts
PB  - Tufts University Health & Nutrition Letter
SN  - 1526-0143
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107898933&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104033683
T1  - health bytes.
AU  - Attwood, Carol Ann
Y1  - 2013/09//Sep/Oct2013
N1  - Accession Number: 104033683. Language: English. Entry Date: 20140304. Revision Date: 20150710. Publication Type: Journal Article; brief item. Journal Subset: Nursing; USA. 
KW  - Atrial Fibrillation
KW  - Information Resources
KW  - World Wide Web
KW  - Brain Injuries
KW  - Athletic Injuries
KW  - Information Literacy
KW  - Domestic Violence
KW  - Yoga
SP  - 15
EP  - 15
JO  - AAACN Viewpoint
JF  - AAACN Viewpoint
JA  - AAACN VIEWPOINT
VL  - 35
IS  - 5
CY  - Pitman, New Jersey
PB  - American Academy of Ambulatory Care Nursing
AD  - Medical Librarian, Patient Health and Education Library, Mayo Clinic Arizona, Scottsdale, AZ
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104033683&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 113632935
T1  - Health Wire.
Y1  - 2016/05//
N1  - Accession Number: 113632935. Language: English. Entry Date: 20160311. Revision Date: 20160316. Publication Type: Article. Journal Subset: Consumer Health; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9425420. 
KW  - Restaurants
KW  - Electronic Cigarettes
KW  - Vitamins
KW  - Sex
KW  - Drugs, Prescription -- Administration and Dosage
KW  - Weights and Measures -- Methods
KW  - Glaucoma -- Risk Factors
KW  - Health Promotion -- Methods
KW  - Female
KW  - Atrial Fibrillation -- Complications
KW  - Sex Factors
KW  - Yoga
SP  - 3
EP  - 3
JO  - Consumer Reports on Health
JF  - Consumer Reports on Health
JA  - CONSUM REP HEALTH
VL  - 28
IS  - 5
CY  - Yonkers, New York
PB  - Consumers Union
SN  - 1044-3193
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=113632935&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104690913
T1  - health wire.
Y1  - 2011/10//
N1  - Accession Number: 104690913. Language: English. Entry Date: 20111011. Revision Date: 20150711. Publication Type: Journal Article; pictorial. Journal Subset: Consumer Health; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Consumer Health. NLM UID: 9425420. 
KW  - Health
KW  - Health Behavior
KW  - Weight Control
KW  - Marital Status
KW  - Male
KW  - Heart Arrest -- Therapy
KW  - Health Resource Utilization
KW  - Emergency Care -- Utilization
KW  - Vitamin D -- Administration and Dosage
KW  - Dietary Supplements
KW  - Aged
KW  - Mortality
KW  - Diabetes Mellitus, Type 2 -- Diet Therapy
KW  - Nuts
KW  - Antiinflammatory Agents, Non-Steroidal -- Adverse Effects
KW  - Atrial Fibrillation -- Chemically Induced
KW  - Massage
KW  - Low Back Pain -- Therapy
KW  - Family History
KW  - Cancer Screening
KW  - Adult
KW  - Middle Age
SP  - 2
EP  - 3
JO  - Consumer Reports on Health
JF  - Consumer Reports on Health
JA  - CONSUM REP HEALTH
VL  - 23
IS  - 10
CY  - Yonkers, New York
PB  - Consumers Union
SN  - 1044-3193
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104690913&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105687700
T1  - Health wire.
Y1  - 2008/11//
N1  - Accession Number: 105687700. Language: English. Entry Date: 20081114. Revision Date: 20150711. Publication Type: Journal Article; brief item; pictorial. Journal Subset: Consumer Health; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Consumer Health. NLM UID: 9425420. 
KW  - Health
KW  - Health Behavior
KW  - Adult
KW  - Alcoholism -- Complications
KW  - Atrial Fibrillation -- Etiology
KW  - Australia
KW  - Blacks
KW  - Diet Records
KW  - Diet, Reducing
KW  - Orthopedic Surgery
KW  - Personal Satisfaction
KW  - Physician-Patient Relations
KW  - Prediabetic State -- Etiology
KW  - Surgeons
KW  - Warfarin -- Therapeutic Use
KW  - Whites
SP  - 2
EP  - 3
JO  - Consumer Reports on Health
JF  - Consumer Reports on Health
JA  - CONSUM REP HEALTH
VL  - 20
IS  - 11
CY  - Yonkers, New York
PB  - Consumers Union
SN  - 1044-3193
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105687700&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105157541
T1  - Heard by the editors.
Y1  - 2010/04//2010 Apr
N1  - Accession Number: 105157541. Language: English. Entry Date: 20100507. Revision Date: 20150711. Publication Type: Journal Article; brief item. Journal Subset: Consumer Health; USA. Special Interest: Consumer Health. NLM UID: 9891730. 
KW  - Atrial Fibrillation -- Risk Factors
KW  - Diabetes Mellitus -- Complications
KW  - Diet, Reducing
KW  - Milk
KW  - Stroke -- Risk Factors
SP  - 3
EP  - 3
JO  - Bottom Line Health
JF  - Bottom Line Health
JA  - BOTTOM LINE HEALTH
VL  - 24
IS  - 4
CY  - Greenwich, Connecticut
PB  - Health Confidential
SN  - 1092-0129
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105157541&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107937003
T1  - Heart Arrhythmias: An Exercise Professional's Primer.
AU  - Kravitz, Len
Y1  - 2013/11//Nov/Dec2013
N1  - Accession Number: 107937003. Language: English. Entry Date: 20131115. Revision Date: 20150712. Publication Type: Journal Article; pictorial; questions and answers; tables/charts. Note: CE page 87. Journal Subset: Allied Health; Consumer Health; Peer Reviewed; USA. Special Interest: Consumer Health; Sports Medicine. 
KW  - Exercise
KW  - Arrhythmia
KW  - Education, Continuing (Credit)
KW  - Exercise Physiology
KW  - Heart -- Physiology
KW  - Sinoatrial Node
KW  - Arrhythmia -- Physiopathology
KW  - Arrhythmia -- Complications
KW  - Arrhythmia, Atrial
KW  - Atrial Fibrillation
KW  - Oxygenation
KW  - Premature Ventricular Contractions
KW  - Premature Atrial Contractions
KW  - Long QT Syndrome
KW  - Heart Block
KW  - Sick Sinus Syndrome
KW  - Bradycardia
KW  - Myocardial Infarction -- Symptoms
KW  - Personal Trainers
SP  - 18
EP  - 21
JO  - IDEA Fitness Journal
JF  - IDEA Fitness Journal
JA  - IDEA FITNESS J
VL  - 10
IS  - 10
CY  - San Diego, California
PB  - IDEA Health & Fitness, Inc.
SN  - 1548-419X
AD  - Program coordinator of exercise science and a researcher , University of New Mexico, Albuquerque.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107937003&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104498914
T1  - Heart failure: recent advances in diagnosis and management.
AU  - Davis, Russel
Y1  - 2012/07//
N1  - Accession Number: 104498914. Language: English. Entry Date: 20120928. Revision Date: 20150711. Publication Type: Journal Article; diagnostic images; exam questions; pictorial; tables/charts. Journal Subset: Biomedical; USA. NLM UID: 9503766. 
KW  - Disease Management
KW  - Heart Failure -- Diagnosis
KW  - Adrenergic Beta-Antagonists -- Therapeutic Use
KW  - Anemia
KW  - Atrial Fibrillation
KW  - Defibrillators
KW  - Diabetes Mellitus
KW  - Diuretics -- Therapeutic Use
KW  - Electrocardiography
KW  - Eplerenone -- Therapeutic Use
KW  - Exercise
KW  - Heart Failure -- Etiology
KW  - Heterocyclic Compounds -- Therapeutic Use
KW  - Metformin -- Administration and Dosage
KW  - Metformin -- Therapeutic Use
KW  - Peptides
KW  - Pioglitazone -- Therapeutic Use
KW  - Professional Development
KW  - Rehabilitation
KW  - Spironolactone -- Therapeutic Use
KW  - Ventricular Ejection Fraction
SP  - 15
EP  - 25
JO  - Prescriber
JF  - Prescriber
JA  - PRESCRIBER
VL  - 23
IS  - 13/14
CY  - Hoboken, New Jersey
PB  - John Wiley & Sons, Inc.
SN  - 0959-6682
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104498914&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105695314
T1  - Heart flutters.
Y1  - 2008/10//
N1  - Accession Number: 105695314. Language: English. Entry Date: 20081121. Revision Date: 20150711. Publication Type: Journal Article; brief item. Journal Subset: Consumer Health; USA. Special Interest: Consumer Health; Nutrition. NLM UID: 8809327. 
KW  - Aged
KW  - Atrial Fibrillation -- Complications
KW  - Atrial Fibrillation -- Risk Factors
KW  - Exercise
KW  - Self Care
KW  - Stroke -- Prevention and Control
KW  - Stroke -- Risk Factors
KW  - Walking
SP  - 8
EP  - 8
JO  - Nutrition Action Health Letter
JF  - Nutrition Action Health Letter
JA  - NUTR ACTION HEALTHLETT
VL  - 35
IS  - 8
CY  - Washington, District of Columbia
PB  - Center for Science in the Public Interest
SN  - 0885-7792
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105695314&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109742096
T1  - High intra- and inter-individual variability of plasma vitamin K concentrations in patients with atrial fibrillation under warfarin therapy.
AU  - Kim, Y-E
AU  - Woo, H I
AU  - On, Y K
AU  - Kim, J S
AU  - Lee, S-Y
Y1  - 2015/06//
N1  - Accession Number: 109742096. Language: English. Entry Date: 20150923. Revision Date: 20160531. Publication Type: journal article. Journal Subset: Biomedical; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Special Interest: Nutrition. NLM UID: 8804070. 
SP  - 703
EP  - 706
JO  - European Journal of Clinical Nutrition
JF  - European Journal of Clinical Nutrition
JA  - EUR J CLIN NUTR
VL  - 69
IS  - 6
CY  - London, <Blank>
PB  - Nature Publishing Group
AB  - Background/objectives: Vitamin K intake is considered as a controllable contributor to warfarin sensitivity. It is restricted in warfarin-treated patients. However, little study has assessed the vitamin K status in warfarin-treated patients. We directly measured plasma vitamin K in warfarin-treated patients and evaluated its effect on anticoagulation.Subjects/methods: A total of 302 plasma vitamin K concentrations were assessed using high-performance liquid chromatography for 203 outpatients with atrial fibrillation under warfarin treatment. Clinical and laboratory information including warfarin dosage, plasma warfarin concentrations, prothrombin time international normalized ratio (PT INR) and CYP2C9/VKORC1 genotypes was reviewed retrospectively. The anticoagulation stability (intra-individual variability, frequency of PT INR tests and complications) was investigated in 163 patients with long-term warfarin therapy. Plasma vitamin K was measured in 40 healthy subjects and in 40 patients before and after initial warfarin treatment.Results: Vitamin K concentrations were significantly decreased after the initiation of warfarin treatment (before treatment: 1.72 ng/ml; after treatment: 0.59 ng/ml, P<0.05). There was a large inter-individual variability in vitamin K levels (0.2-4.2 ng/ml) in warfarin-treated patients. PT INR was more frequently checked in patients with low plasma vitamin K levels than in those with high vitamin K levels (9.5 times/year vs 7.5 times/year, P=0.029). Two patients with gross hematuria showed very low vitamin K levels (<0.4 ng/ml).Conclusions: We found high inter- and intra-individual variability in vitamin K concentration in warfarin-treated patients. Low vitamin K concentration in warfarin-treated patients suggested excessive dietary restriction. Plasma vitamin K measurement would be helpful for dietary control and anticoagulation stability.
SN  - 0954-3007
U2  - PMID: 25828628.
DO  - 10.1038/ejcn.2015.41
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109742096&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 111176487
T1  - High-intensity interval training improves cardiovascular health, exercise capacity, and quality of life in permanent atrial fibrillation: a case study.
AU  - Reed, Jennifer L.
AU  - Nery, Pablo B.
AU  - Birnie, David H.
AU  - Tulloch, Heather E.
AU  - Pipe, Andrew L.
Y1  - 2015/12//
N1  - Accession Number: 111176487. Language: English. Entry Date: 20151130. Revision Date: 20151201. Publication Type: Article. Journal Subset: Biomedical; Canada; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed. Instrumentation: Short Form 36 Health Survey (SF-36). NLM UID: 101264333. 
KW  - Exercise Physiology
KW  - Atrial Fibrillation -- Therapy
KW  - Quality of Life -- In Old Age
KW  - Therapeutic Exercise
KW  - Male
KW  - Human
KW  - Aged
KW  - Echocardiography
KW  - Hypertension
KW  - Body Mass Index
KW  - Questionnaires
KW  - Heart Rate
KW  - Waist Circumference
KW  - Ergometry
SP  - 1321
EP  - 1323
JO  - Applied Physiology, Nutrition & Metabolism
JF  - Applied Physiology, Nutrition & Metabolism
JA  - APPL PHYSIOL NUTR METAB
VL  - 40
IS  - 12
CY  - Ottawa, Ontario
PB  - Canadian Science Publishing
SN  - 1715-5312
AD  - University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada.
DO  - 10.1139/apnm-2015-0356
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=111176487&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105347017
T1  - How to avoid a heart attack: putting it all together.
AU  - Haffey TA
Y1  - 2009/05/02/2009 May Supplement 1
N1  - Accession Number: 105347017. Language: English. Entry Date: 20090724. Revision Date: 20150711. Publication Type: Journal Article; pictorial; review; tables/charts. Supplement Title: 2009 May Supplement 1. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Evidence-Based Practice. Instrumentation: Patient Health Questionnaire (PHQ). NLM UID: 7503065. 
KW  - Health Behavior
KW  - Life Style Changes
KW  - Metabolic Syndrome X
KW  - Myocardial Infarction -- Prevention and Control
KW  - Preventive Health Care
KW  - Abdomen
KW  - Adipose Tissue Distribution
KW  - Alcohol Drinking
KW  - Antihypertensive Agents -- Therapeutic Use
KW  - Apolipoproteins -- Blood
KW  - C-Reactive Protein -- Blood
KW  - Cholesterol -- Blood
KW  - Depression -- Prevention and Control
KW  - Diabetes Mellitus -- Prevention and Control
KW  - Diet
KW  - Education, Continuing (Credit)
KW  - Exercise
KW  - Fatty Acids, Omega-3 -- Therapeutic Use
KW  - Fruit
KW  - Hypertension -- Prevention and Control
KW  - Lipoproteins, HDL Cholesterol -- Blood
KW  - Lipoproteins, LDL Cholesterol -- Blood
KW  - Medical Practice, Evidence-Based
KW  - Niacin -- Therapeutic Use
KW  - Obesity -- Prevention and Control
KW  - Psychological Tests
KW  - Questionnaires
KW  - Smoking
KW  - Smoking Cessation
KW  - Statins -- Therapeutic Use
KW  - Triglycerides -- Blood
KW  - Vegetables
KW  - Weight Control -- Methods
SP  - S14
EP  - 20
JO  - JAOA: Journal of the American Osteopathic Association
JF  - JAOA: Journal of the American Osteopathic Association
JA  - JAOA J AM OSTEOPATH ASSOC
VL  - 109
IS  - 5
CY  - Chicago, IL 60611, Illinois
PB  - American Osteopathic Association
AB  - Cardiovascular disease (eg, myocardial infarction, ischemic stroke) is the leading cause of death in patients who have metabolic syndrome and diabetes mellitus. By effectively treating the whole patient, however, the risk of death from cardiovascular disease can be reduced or prevented. The author describes clinical approaches for achieving this goal. He reviews information that is useful to know about patients regarding modifiable and potentially modifiable risk factors for cardiovascular disease, including hypertension, hyperlipidemia, smoking, activity levels, dietary habits, obesity, carotid artery stenosis, and atrial fibrillation. He also notes the importance of evaluating patients for relevant psychosocial factors such as depression. Finally, the author analyzes treatment options for patients, including effective medications, dietary modification, and exercise--emphasizing the use of pedometers--as well as participation by patients in weight-control support groups.
SN  - 0098-6151
AD  - Professor of Medicine, Western University of Health Sciences College of Osteopathic Medicine of the Pacific, Pomona, CA; thaffey@yahoo.com
U2  - PMID: 19451253.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105347017&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104217405
T1  - How to lower your stroke risk.
Y1  - 2013/08//
N1  - Accession Number: 104217405. Language: English. Entry Date: 20130827. Revision Date: 20150711. Publication Type: Journal Article; pictorial. Journal Subset: Biomedical; USA. NLM UID: 9425723. 
KW  - Stroke -- Prevention and Control
KW  - Risk Factors -- Prevention and Control
KW  - Smoking -- Prevention and Control
KW  - Weight Loss
KW  - Alcohol Drinking -- Prevention and Control
KW  - Sodium Chloride -- Administration and Dosage
KW  - Diet
KW  - Exercise
KW  - Hypertension -- Prevention and Control
KW  - Atherosclerosis -- Prevention and Control
KW  - Atrial Fibrillation -- Complications
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Diabetes Mellitus -- Complications
SP  - 3
EP  - 3
JO  - Harvard Heart Letter
JF  - Harvard Heart Letter
JA  - HARV HEART LETT
VL  - 23
IS  - 12
CY  - Stamford, Connecticut
PB  - Harvard Health Publications
SN  - 1051-5313
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104217405&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104804671
T1  - How to prevent a first-time stroke.
AU  - Llinas, Rafael H.
Y1  - 2011/07//2011 Jul
N1  - Accession Number: 104804671. Language: English. Entry Date: 20110708. Revision Date: 20150711. Publication Type: Journal Article; pictorial; practice guidelines. Journal Subset: Consumer Health; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Consumer Health. NLM UID: 9802902. 
KW  - Health Behavior
KW  - Health Promotion
KW  - Stroke -- Prevention and Control
KW  - Stroke -- Risk Factors
KW  - Aspirin
KW  - Atrial Fibrillation
KW  - Blood Pressure
KW  - Diabetes Mellitus
KW  - Diet
KW  - Passive Smoking
KW  - Prevalence
KW  - United States
SP  - 1
EP  - 2
JO  - Johns Hopkins Medical Letter: Health After 50
JF  - Johns Hopkins Medical Letter: Health After 50
JA  - JOHNS HOPKINS MED LETT HEALTH AFTER 50
VL  - 23
IS  - 5
CY  - New York, New York
PB  - Scientific American
SN  - 1042-1882
AD  - Associate Professor of Neurology, Johns Hopkins Hospital
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104804671&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105478122
T1  - Impact of proteinuria and glomerular filtration rate on risk of thromboembolism in atrial fibrillation: the anticoagulation and risk factors in atrial fibrillation (ATRIA) study.
AU  - Go AS
AU  - Fang MC
AU  - Udaltsova N
AU  - Chang Y
AU  - Pomernacki NK
AU  - Borowsky L
AU  - Singer DE
Y1  - 2009/03/17/
N1  - Accession Number: 105478122. Corporate Author: ATRIA Study Investigators. Language: English. Entry Date: 20090508. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0147763. 
KW  - Atrial Fibrillation -- Epidemiology
KW  - Glomerular Filtration Rate
KW  - Kidney Diseases -- Epidemiology
KW  - Proteinuria -- Epidemiology
KW  - Thromboembolism -- Epidemiology
KW  - Adult
KW  - Aged
KW  - Anticoagulants -- Therapeutic Use
KW  - Atrial Fibrillation -- Complications
KW  - California
KW  - Chronic Disease
KW  - Comorbidity
KW  - Creatinine -- Blood
KW  - Female
KW  - Fibrinolytic Agents -- Therapeutic Use
KW  - Kidney Diseases -- Complications
KW  - Kidney Diseases -- Physiopathology
KW  - Kidney Diseases -- Urine
KW  - Male
KW  - Middle Age
KW  - Prospective Studies
KW  - Risk Factors
KW  - Stroke -- Prevention and Control
KW  - Thromboembolism -- Etiology
KW  - Thromboembolism -- Prevention and Control
KW  - Warfarin -- Therapeutic Use
KW  - Human
SP  - 1363
EP  - 1369
JO  - Circulation
JF  - Circulation
JA  - CIRCULATION
VL  - 119
IS  - 10
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - BACKGROUND: Atrial fibrillation (AF) substantially increases the risk of ischemic stroke, but this risk varies among individual patients with AF. Existing risk stratification schemes have limited predictive ability. Chronic kidney disease is a major cardiovascular risk factor, but whether it independently increases the risk for ischemic stroke in persons with AF is unknown. METHODS AND RESULTS: We examined how chronic kidney disease (reduced glomerular filtration rate or proteinuria) affects the risk of thromboembolism off anticoagulation in patients with AF. We estimated glomerular filtration rate using the Modification of Diet in Renal Disease equation and proteinuria from urine dipstick results found in laboratory databases. Patient characteristics, warfarin use, and thromboembolic events were ascertained from clinical databases, with validation of thromboembolism by chart review. During 33,165 person-years off anticoagulation among 10,908 patients with AF, we observed 676 incident thromboembolic events. After adjustment for known risk factors for stroke and other confounders, proteinuria increased the risk of thromboembolism by 54% (relative risk, 1.54; 95% CI, 1.29 to 1.85), and there was a graded, increased risk of stroke associated with a progressively lower level of estimated glomerular filtration rate compared with a rate > or =60 mL x min(-1) x 1.73 m(-2): relative risk of 1.16 (95% CI, 0.95 to 1.40) for estimated glomerular filtration rate of 45 to 59 mL x min(-1) x 1.73 m(-2) and 1.39 (95% CI, 1.13 to 1.71) for estimated glomerular filtration rate <45 mL x min(-1) x 1.73 m(-2) (P=0.0082 for trend). CONCLUSIONS: Chronic kidney disease increases the risk of thromboembolism in AF independently of other risk factors. Knowing the level of kidney function and the presence of proteinuria may improve risk stratification for decision making about the use of antithrombotic therapy for stroke prevention in AF.
SN  - 0009-7322
AD  - Division of Research, Kaiser Permanente of Northern California, 2000 Broadway St, 3rd Floor, Oakland, CA 94612, USA. Alan.S.Go@kp.org
U2  - PMID: 19255343.
DO  - 10.1161/CIRCULATIONAHA.108.816082
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105478122&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103825072
T1  - Impaired renal function in stroke patients with atrial fibrillation.
AU  - Sauer, Eva-Maria
AU  - Sauer, Roland
AU  - Kallmünzer, Bernd
AU  - Blinzler, Christian
AU  - Breuer, Lorenz
AU  - Huttner, Hagen B
AU  - Schwab, Stefan
AU  - Köhrmann, Martin
Y1  - 2014/05//May/Jun2014
N1  - Accession Number: 103825072. Language: English. Entry Date: 20150206. Revision Date: 20150710. Publication Type: Journal Article; research. Journal Subset: Biomedical; Double Blind Peer Reviewed; Peer Reviewed; USA. Instrumentation: Modified Rankin Scale. NLM UID: 9111633. 
KW  - Atrial Fibrillation -- Complications
KW  - Kidney Diseases -- Complications
KW  - Kidney -- Physiopathology
KW  - Stroke -- Etiology
KW  - Aged
KW  - Aged, 80 and Over
KW  - Atrial Fibrillation -- Diagnosis
KW  - Atrial Fibrillation -- Mortality
KW  - Atrial Fibrillation -- Physiopathology
KW  - Atrial Fibrillation -- Therapy
KW  - Chi Square Test
KW  - Comorbidity
KW  - Female
KW  - Glomerular Filtration Rate
KW  - Human
KW  - Kidney Diseases -- Diagnosis
KW  - Kidney Diseases -- Mortality
KW  - Kidney Diseases -- Physiopathology
KW  - Kidney Diseases -- Therapy
KW  - Logistic Regression
KW  - Male
KW  - Multivariate Analysis
KW  - Odds Ratio
KW  - Patient Admission
KW  - Prognosis
KW  - Recovery
KW  - Retrospective Design
KW  - Risk Factors
KW  - Scales
KW  - Stroke -- Diagnosis
KW  - Stroke -- Mortality
KW  - Stroke -- Physiopathology
KW  - Stroke -- Therapy
KW  - Time Factors
SP  - 1225
EP  - 1228
JO  - Journal of Stroke & Cerebrovascular Diseases
JF  - Journal of Stroke & Cerebrovascular Diseases
JA  - J STROKE CEREBROVASC DIS
VL  - 23
IS  - 5
CY  - Philadelphia, Pennsylvania
PB  - W B Saunders
AB  - BACKGROUND: Stroke patients with atrial fibrillation (AF) are prone to have comorbidities such as impaired renal function. Because poly-pharmacotherapy is often required in those patients, renal function is important to consider in light of renally cleared medications such as direct oral anticoagulants. In this study, we analyzed frequency and predictors for impaired renal function and its impact on functional outcome in stroke patients with underlying AF. METHODS: We analyzed 272 patients with acute ischemic stroke and AF of our prospective, observational stroke database. Estimated glomerular filtration rate (eGFR) was calculated on admission and during hospitalization from the equation of the Modification Diet for Renal Disease. Outcome measures included mortality and functional outcome at 90 days, assessed as modified Rankin Scale (mRS) score. RESULTS: On admission, impaired renal function was found in 41.5% (n = 113) and was associated with worse 90-day outcome (mRS score <= 2: 26.5% versus 45.9%, P = .001) and a higher mortality rate (23.9% versus 14.5%, P = .043). Multivariate logistic regression identified older age and history of myocardial infarction as independent predictors of renal dysfunction on admission (P < .05). Normalization of eGFR during hospitalization was achieved in 55.8%. CONCLUSIONS: In patients with acute ischemic stroke and AF, impaired renal function on admission is frequent and associated with worse outcome. Normalization of eGFR can often be achieved during hospitalization, but in everyday life, fluctuations of renal function because of infection or dehydration have to be considered. Careful monitoring of renal status is indispensable and should influence drug treatment decisions.
SN  - 1052-3057
AD  - Department of Neurology, Universitätsklinikum Erlangen, Erlangen, Germany. Electronic address: Eva-Maria.Sauer@uk-erlangen.de.
AD  - Department of Neuroradiology, Universitätsklinikum Erlangen, Erlangen, Germany.
AD  - Department of Neurology, Universitätsklinikum Erlangen, Erlangen, Germany.
U2  - PMID: 24280266.
DO  - 10.1016/j.jstrokecerebrovasdis.2013.10.020
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105904713
T1  - Improved care for patients with congestive heart failure.
AU  - Jacobsen D
AU  - Sevin C
Y1  - 2008/01//2008 Jan
N1  - Accession Number: 105904713. Language: English. Entry Date: 20080502. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Editorial Board Reviewed; Expert Peer Reviewed; Health Services Administration; Peer Reviewed; USA. Special Interest: Evidence-Based Practice; Patient Safety; Quality Assurance. NLM UID: 101238023. 
KW  - Heart Failure -- Therapy
KW  - Quality of Health Care
KW  - Adrenergic Beta-Antagonists -- Therapeutic Use
KW  - After Care
KW  - Communication
KW  - Consumer Participation
KW  - Counseling
KW  - Heart Failure -- Drug Therapy
KW  - Inpatients
KW  - Medical Care
KW  - Patient Assessment
KW  - Patient Discharge
KW  - Practice Guidelines
KW  - Professional Practice, Evidence-Based
KW  - Quality Improvement
KW  - Questionnaires
KW  - Readmission
KW  - Ventricular Dysfunction, Left
SP  - 13
EP  - 19
JO  - Joint Commission Journal on Quality & Patient Safety
JF  - Joint Commission Journal on Quality & Patient Safety
JA  - JOINT COMM J QUAL PATIENT SAF
VL  - 34
IS  - 1
CY  - West Oak Brook, Illinois
PB  - Joint Commission Resources
AB  - Background: Congestive heart failure (CHF) affects 4.9 million people, mostly elderly, in the United States; 550,000 new cases are diagnosed each year. Evidence-based treatment approaches offer opportunities to reduce mortality, complications, and rehospitalization rates.Strategies to Improve Care for Patients with Congestive Heart Failure: Seven key components of care tailored to the patient's clinical condition and comorbidities that should be provided to all patients with CHF, in the absence of contraindications or intolerance: (1) left ventricular systolic function assessment, (2) angiotension-converting enzyme-inhibitor or angiotensin receptor blockers at discharge for CHF patients with systolic dysfunction (left ventricular ejection fraction < 40%), (3) anticoagulation at discharge for CHF patients with chronic or recurrent atrial fibrillation, (4) smoking cessation advice and counseling, (5) discharge instructions that address activity level, diet, discharge medications, follow-up appointment, weight monitoring, and what to do if symptoms worsen, (6) influenza immunization (seasonal), and (7) pneumococcal immunization. Hospitals should also consider beta-blocker therapy at discharge for stabilized patients without contraindications.Conclusion: The 5 Million Lives Campaign's focus on delivering reliable, evidence-based care for patients with CHF is part of an overall strategy to reduce medically induced harm.
SN  - 1553-7250
AD  - Directors, Institute for Healthcare Improvements, Cambridge, Massachusetts; djacobsen@ihi.org
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105436866
T1  - Improved oral anticoagulation after a dietary vitamin k-guided strategy: a randomized controlled trial.
AU  - de Assis MC
AU  - Rabelo ER
AU  - Avila CW
AU  - Polanczyk CA
AU  - Rohde LE
Y1  - 2009/09/22/
N1  - Accession Number: 105436866. Language: English. Entry Date: 20091023. Revision Date: 20150711. Publication Type: Journal Article; research; randomized controlled trial. Commentary: Crawford MH. Dietary manipulation to stabilize INR [corrected] [published erratum appears in CLIN CARDIOL ALERT 2009 Dec;28(12):96]. (CLIN CARDIOL ALERT) Nov2009; 28 (11): 87-88; Booth SL. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? (NUTR REV) Mar2010; 68 (3): 178-181. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Evidence-Based Practice. NLM UID: 0147763. 
KW  - Anticoagulants -- Administration and Dosage
KW  - Vitamin K -- Administration and Dosage
KW  - Administration, Oral
KW  - Adult
KW  - Aged
KW  - Randomized Controlled Trials
KW  - Crossover Design
KW  - Diet
KW  - Female
KW  - International Normalized Ratio
KW  - Male
KW  - Middle Age
KW  - Human
SP  - 1115
EP  - 3p
JO  - Circulation
JF  - Circulation
JA  - CIRCULATION
VL  - 120
IS  - 12
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - BACKGROUND: Dietary vitamin K is thought to be an important factor that interferes with anticoagulation stability, but the clinical applicability of this interaction has not been evaluated adequately in prospective studies. METHODS AND RESULTS: In a randomized controlled trial that enrolled outpatients with a recent international normalized ratio (INR) outside the therapeutic target, we compared 2 strategies to optimize long-term oral anticoagulation: (1) a conventional approach based on changes in anticoagulant prescription and (2) a dietary vitamin K-guided strategy based on simple modifications of the amount of vitamin K-rich foods ingested per week. The primary efficacy end point was the percentage of patients who achieved a prespecified INR target at 90 days after randomization. Study population (n=132) predominantly included men with mechanical heart prostheses (58%) or atrial fibrillation (35%). Over time, patients allocated to the vitamin K-guided strategy reached the prespecified INR more frequently so that after 90 days of follow-up, 74% were on target compared with 58% of patients managed conventionally (P=0.04). Patients allocated to the dietary vitamin K-guided strategy had the same magnitude and direction of INR variation as those observed with the conventional approach in the short term (15 days) for both underanticaogulated and overanticoagulated patients. Minor bleeding or use of parenteral vitamin K were also marginally less frequent in patients managed according to the dietary intervention (1 [1.5%] versus 7 [11%]; P=0.06). CONCLUSIONS: A vitamin K-guided management strategy to adjust long-term oral anticoagulation is feasible and safe and may result in an increased chance of reaching target levels of INR.
SN  - 0009-7322
AD  - Cardiovascular Division of Hospital de Clínicas de Porto Alegre, Postgraduation Program in Cardiology and Cardiovascular Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
U2  - PMID: 19738137.
DO  - 10.1161/CIRCULATIONAHA.109.849208
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105436866&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106315059
T1  - In brief.
Y1  - 2006/04/25/2006 Apr 25-May 1
N1  - Accession Number: 106315059. Language: English. Entry Date: 20060811. Revision Date: 20150711. Publication Type: Journal Article; abstract. Supplement Title: 2006 Apr 25-May 1. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 0423236. 
KW  - Atrial Fibrillation -- Risk Factors
KW  - Chest Pain -- Prevention and Control
KW  - Hypnosis
KW  - Lung Neoplasms -- Prognosis
KW  - Smoking -- Complications
SP  - 6
EP  - 6
JO  - Nursing Times
JF  - Nursing Times
JA  - NURS TIMES
VL  - 102
IS  - 17
PB  - EMAP Healthcare
SN  - 0954-7762
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106315059&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104051402
T1  - In overweight or obese patients with atrial fibrillation, a weight reduction program reduced symptoms.
AU  - Wyse, D. George
Y1  - 2014/03/18/
N1  - Accession Number: 104051402. Language: English. Entry Date: 20140321. Revision Date: 20150710. Publication Type: Journal Article; abstract; commentary. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Evidence-Based Practice. Instrumentation: Atrial Fibrillation Severity Scale (AFSS). NLM UID: 9104824. 
KW  - Atrial Fibrillation -- Symptoms
KW  - Obesity -- Therapy
KW  - Weight Control -- Methods
KW  - Severity of Illness
KW  - Outcomes (Health Care)
KW  - Randomized Controlled Trials
KW  - South Australia
KW  - Male
KW  - Female
KW  - Adult
KW  - Middle Age
KW  - Aged
KW  - Body Mass Index
KW  - Waist Circumference
KW  - International Normalized Ratio
KW  - Diet, Reducing
KW  - Exercise Intensity
KW  - Cardiovascular Risk Factors
KW  - Scales
KW  - Descriptive Statistics
KW  - Confidence Intervals
KW  - Summated Rating Scaling
SP  - 1
EP  - 1
JO  - ACP Journal Club
JF  - ACP Journal Club
JA  - ACP J CLUB
VL  - 160
IS  - 6
CY  - Philadelphia, Pennsylvania
PB  - American College of Physicians
SN  - 1056-8751
AD  - Libin Cardiovascular Institute of Alberta,Calgary, Alberta, Canada
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104051402&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103760408
T1  - IN THE JOURNALS.
Y1  - 2015/03//
N1  - Accession Number: 103760408. Language: English. Entry Date: 20150219. Revision Date: 20150710. Publication Type: Journal Article; pictorial. Journal Subset: Consumer Health; USA. Special Interest: Consumer Health; Men's Health. NLM UID: 9802701. 
KW  - Sleep
KW  - Exercise
KW  - Age Factors
KW  - Academic Medical Centers
KW  - Serial Publications
KW  - Male
KW  - Middle Age
KW  - Muscle Strength -- Evaluation
KW  - Atrial Fibrillation -- Therapy
KW  - Hemorrhage -- Risk Factors
KW  - Antiinflammatory Agents, Non-Steroidal -- Therapeutic Use
KW  - Antiinflammatory Agents, Non-Steroidal -- Adverse Effects
KW  - Hypertension -- Therapy
KW  - Heart Diseases -- Prevention and Control
SP  - 8
EP  - 8
JO  - Harvard Men's Health Watch
JF  - Harvard Men's Health Watch
JA  - HARV MENS HEALTH WATCH
VL  - 19
IS  - 8
CY  - Stamford, Connecticut
PB  - Harvard Health Publications
SN  - 1089-1102
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103760408&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 110101986
T1  - Incidence and Predictors of Hemorrhagic Stroke in Users of Low-Dose Acetylsalicylic Acid.
AU  - González-Pérez, Antonio
AU  - Sáez, María Eugenia
AU  - Johansson, Saga
AU  - Himmelmann, Anders
AU  - García Rodríguez, Luis A.
Y1  - 2015/10//
N1  - Accession Number: 110101986. Language: English. Entry Date: 20160709. Revision Date: 20160714. Publication Type: journal article. Journal Subset: Biomedical; Double Blind Peer Reviewed; Peer Reviewed; USA. Instrumentation: Appraisal of Self-Care Agency Scale; Checklist Individual Strength (CIS). NLM UID: 9111633. 
KW  - Intracranial Hemorrhage -- Epidemiology
KW  - Fibrinolytic Agents -- Adverse Effects
KW  - Stroke -- Epidemiology
KW  - Stroke -- Diagnosis
KW  - Stroke -- Etiology
KW  - Aspirin -- Adverse Effects
KW  - Predictive Value of Tests
KW  - Aged, 80 and Over
KW  - Middle Age
KW  - Risk Factors
KW  - Prospective Studies
KW  - Female
KW  - Intracranial Hemorrhage -- Complications
KW  - Incidence
KW  - Male
KW  - Age Factors
KW  - Aged
KW  - Checklists
KW  - Scales
SP  - 2321
EP  - 2328
JO  - Journal of Stroke & Cerebrovascular Diseases
JF  - Journal of Stroke & Cerebrovascular Diseases
JA  - J STROKE CEREBROVASC DIS
VL  - 24
IS  - 10
CY  - Philadelphia, Pennsylvania
PB  - W B Saunders
AB  - Background: The use of antithrombotic drugs (anticoagulants and antiplatelet drugs) has been reported to increase the risk of hemorrhagic stroke (HS) relative to no treatment. This study was performed to characterize the incidence and predictors of HS in users of acetylsalicylic acid (ASA) for the secondary prevention of cardiovascular events.Methods: A cohort of 36,775 ASA users aged 50-84 years in 2000-2007 was identified from The Health Improvement Network database. The incidence of HS was calculated, and a nested case-control analysis, adjusted for potential confounding factors, was performed to calculate the odds ratios (ORs) and 95% confidence intervals (CIs) for the association of potential risk factors with HS in current users of ASA.Results: The overall incidence of HS was 5.70 cases per 10,000 person-years and increased with age. In current ASA users, the incidence of HS was 4.91 cases per 10,000 person-years. Predictors of HS in patients taking ASA for secondary prevention included a history of HS (OR, 4.84; 95% CI, 1.48-15.88), a history of atrial fibrillation (OR, 4.03; 95% CI, 1.53-10.62), and hypnotic/anxiolytic drug use (OR, 2.67; 95% CI, 1.17-6.05). The small number of patients using warfarin also had an increased risk of HS (OR, 23.42; 95% CI, 4.89-112.10).Conclusions: Physicians should consider additional risk factors for HS, such as a history of HS or atrial fibrillation, and the use of warfarin, before prescribing ASA for the secondary prevention of cardiovascular events.
SN  - 1052-3057
AD  - Spanish Centre for Pharmacoepidemiologic Research (CEIFE), Madrid, Spain
AD  - Andalusian Bioinformatics Research Center (CAEBi), Seville, Spain
AD  - Global Medicines Development, Medical Affairs, Observational Research Center, AstraZeneca R&D, Mölndal, Sweden
U2  - PMID: 26189158.
DO  - 10.1016/j.jstrokecerebrovasdis.2015.06.016
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106260753
T1  - Informing practice.
AU  - Kayyali A
AU  - Lindsey H
Y1  - 2007/03//
N1  - Accession Number: 106260753. Language: English. Entry Date: 20070406. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. NLM UID: 0372646. 
KW  - Patient Care
KW  - Adult
KW  - Aged
KW  - Anticoagulants -- Adverse Effects
KW  - Anticoagulants -- Therapeutic Use
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Cardiac Patients
KW  - Stroke -- Prevention and Control
KW  - Clinical Trials
KW  - Coronary Disease -- Therapy
KW  - Female
KW  - Heart Failure -- Mortality
KW  - Male
KW  - Meditation
KW  - Prospective Studies
KW  - Systematic Review
KW  - Systolic Pressure
KW  - United States
SP  - 72A
EP  - B
JO  - American Journal of Nursing
JF  - American Journal of Nursing
JA  - AM J NURS
VL  - 107
IS  - 3
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
SN  - 0002-936X
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106260753&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108026779
T1  - Innovative Mobility Strategies for the Patient With Intensive Care Unit- Acquired Weakness: A Case Report.
AU  - Trees, Darin W.
AU  - Smith, James M.
AU  - Hockert, Steven
Y1  - 2013/02//
N1  - Accession Number: 108026779. Language: English. Entry Date: 20130208. Revision Date: 20150820. Publication Type: Journal Article; case study; pictorial; tables/charts. Journal Subset: Allied Health; Peer Reviewed; USA. Special Interest: Critical Care; Physical Therapy. NLM UID: 0022623. 
KW  - Critical Care -- Adverse Effects
KW  - Deconditioning
KW  - Physical Therapy -- Methods
KW  - Critical Illness -- Rehabilitation
KW  - Muscle Weakness -- Rehabilitation
KW  - Intensive Care Units
KW  - Long Term Care
KW  - Muscle Strengthening -- Methods
KW  - Physical Therapy Assessment
KW  - Muscle Strengthening -- Equipment and Supplies
KW  - Patient Safety
KW  - Weight-Bearing
KW  - Aged
KW  - Female
SP  - 237
EP  - 247
JO  - Physical Therapy
JF  - Physical Therapy
JA  - PHYS THER
VL  - 93
IS  - 2
CY  - Alexandria, Virginia
PB  - American Physical Therapy Association
AB  - Background and Purpose. Although the benefits of early mobilization in the intensive care unit (ICU) have been well documented in recent years, the decision- making process and customization of treatment strategies for patients with ICU- acquired weakness have not been well defined in the literature. This case report will describe a patient with ICU-acquired weakness in the long-term acute care hospital (LTACH) setting and mobilization strategies that include novel devices for therapeutic exercise and gait training. Case Description. A 73-year-old, active woman underwent a routine cardioversion for atrial fibrillation but developed multiple complications, including sepsis and respiratory failure. The patient spent 3 weeks of limited activity in the ICU and was transferred to our LTACH for continued medical intervention and rehabilitation. A 4-phase graded mobilization program was initiated in the LTACH ICU. Within that program, the physical therapy interventions included partial weight-bearing antigravity strength training with a mobile leg press and gait training with a hydraulic-assist platform walker. Outcome. Before interventions, the patient had severe weakness (Medical Research Council [MRC] sum score of 18/60) and displayed complete dependence for all functioning. She progressed to being able to ambulate 150 ft (1 ft=0.3048 m) using a rolling walker with accompanying strength increases to an MRC sum score of 52/60. Discussion. This case report describes novel mobility strategies for managing a patient with ICU-acquired weakness. The application of a graded mobilization program using a mobile leg press and a hydraulic-assist platform walker was safe and feasible, and appeared to expedite the patient's recovery process while decreasing the amount of manual lifting for the therapists.
SN  - 0031-9023
AD  - Rehabilitation and Wound Care, Solara Hospital Conroe, 1500 Grand Lake Dr, Conroe, TX 77304
AD  - Department of Physical Therapy, Utica College, Utica, New York
AD  - Rehabilitation, Solara Hospital Conroe
DO  - 10.2522/ptj.20110401
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108026779&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104220642
T1  - Integrated approach to treatment-resistant atrial fibrillation: additional value of acupuncture.
AU  - Jonkman, F. A. M.
AU  - Jonkman-Buidin, M. L.
Y1  - 2013/09//
N1  - Accession Number: 104220642. Language: English. Entry Date: 20130905. Revision Date: 20150711. Publication Type: Journal Article; case study; tracings. Journal Subset: Alternative/Complementary Therapies; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. NLM UID: 9304117. 
KW  - Acupuncture -- Utilization
KW  - Atrial Fibrillation -- Therapy
KW  - Bronchitis, Chronic -- Complications
KW  - Male
KW  - Middle Age
KW  - Cardioversion
SP  - 327
EP  - 330
JO  - Acupuncture in Medicine
JF  - Acupuncture in Medicine
JA  - ACUPUNCTURE MED
VL  - 31
IS  - 3
PB  - BMJ Publishing Group
AB  - A 62-year-old patient with chronic bronchitis had treatment-resistant atrial fibrillation. Electrical cardioversion was performed, but sinus rhythm (SR) lasted only for some minutes. Administration of amiodarone was withheld in favour of a course of acupuncture treatment in order to increase the success rate of a second attempt of electrical cardioversion. After two acupuncture treatments, spontaneous conversion to SR occurred. Relapses into atrial fibrillation in the following five winters, associated with attacks of bronchitis, also responded to acupuncture. The mechanisms of action of the acupuncture treatment and the value of this integrated approach to treatment are discussed.
SN  - 0964-5284
AD  - Department of Acupuncture, Acupuncture Outpatient Clinic Heel de Mens, Heelsum, The Netherlands; Department of Cardiology, Stichting Cardiologie Heelsum, Heelsum, The Netherlands; Training Centre Acupuncture and Integrative Medicine, Human Balance Teachings, Heelsum, The Netherlands
U2  - PMID: 23884291.
DO  - 10.1136/acupmed-2013-010380
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108191021
T1  - Intensity of anticoagulation with warfarin and risk of adverse events in patients presenting to the emergency department.
AU  - Anthony CJ
AU  - Karim S
AU  - Ackroyd-Stolarz S
AU  - Fry A
AU  - Murphy NG
AU  - Christie R
AU  - Zed PJ
Y1  - 2011/07//2011 Jul
N1  - Accession Number: 108191021. Language: English. Entry Date: 20120323. Revision Date: 20150712. Publication Type: Journal Article; research. Journal Subset: Biomedical; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9203131. 
KW  - Anticoagulants -- Adverse Effects
KW  - Blood Coagulation -- Drug Effects
KW  - Hemorrhage -- Epidemiology
KW  - Thromboembolism -- Epidemiology
KW  - Warfarin -- Adverse Effects
KW  - Aged
KW  - Aged, 80 and Over
KW  - Anticoagulants -- Therapeutic Use
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Canada
KW  - Diet -- Adverse Effects
KW  - Female
KW  - Hemorrhage -- Physiopathology
KW  - Academic Medical Centers
KW  - International Normalized Ratio
KW  - Male
KW  - Middle Age
KW  - Prospective Studies
KW  - Relative Risk
KW  - Severity of Illness Indices
KW  - Thromboembolism -- Physiopathology
KW  - Trauma Centers
KW  - Vitamin K -- Administration and Dosage
KW  - Vitamin K -- Adverse Effects
KW  - Warfarin -- Therapeutic Use
SP  - 881
EP  - 887
JO  - Annals of Pharmacotherapy
JF  - Annals of Pharmacotherapy
JA  - ANN PHARMACOTHER
VL  - 45
IS  - 7-8
CY  - Thousand Oaks, California
PB  - Sage Publications Inc.
SN  - 1060-0280
AD  - Department of Pharmacy, Mt. Sinai Hospital, Toronto, Ontario, Canada.
U2  - PMID: 21750309.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108191021&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

ID  - 117011673
T1  - Interaction between Age and Endurance Exercise on Atrial Remodelling and Ectopy: Implications for Atrial Fibrillation Risk in Athletes.
AU  - Elliott, A.
AU  - Rangnekar, G.
AU  - Mahajan, R.
AU  - Lau, D.
AU  - Middeldorp, M.
AU  - Sanders, P.
Y1  - 2016/08/02/Aug2016 Supplement 2
N1  - Accession Number: 117011673. Language: English. Entry Date: In Process. Revision Date: 20160804. Publication Type: Abstract. Supplement Title: Aug2016 Supplement 2. Journal Subset: Biomedical; Continental Europe; Europe. NLM UID: 100963739. 
SP  - S328
EP  - S328
JO  - Heart, Lung & Circulation
JF  - Heart, Lung & Circulation
JA  - HEART LUNG CIRC
VL  - 25
CY  - New York, New York
PB  - Elsevier Science
SN  - 1443-9506
AD  - Centre for Heart Rhythm Disorders, University of Adelaide, South Australian Health & Medical Research Institute and the Royal Adelaide Hospital, Adelaide, Australia
DO  - 10.1016/j.hlc.2016.06.777
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=117011673&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 113659867
T1  - Interaction Between Dietary Vitamin K Intake and Anticoagulation by Vitamin K Antagonists: Is It Really True?: A Systematic Review.
AU  - Violi, Francesco
AU  - Lip, Gregory Yh
AU  - Pignatelli, Pasquale
AU  - Pastori, Daniele
Y1  - 2016/03//
N1  - Accession Number: 113659867. Language: English. Entry Date: 20160715. Revision Date: 20160714. Publication Type: journal article. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 2985248R. 
SP  - e2895
EP  - e2895
JO  - Medicine
JF  - Medicine
JA  - MEDICINE
VL  - 95
IS  - 9
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - Educational advice is often given to patients starting treatment with vitamin K Antagonists (VKAs). A great emphasis is made on nutritional information. Common belief is that dietary vitamin K intake could counteract the anticoagulant effect by VKAs and for many years, patients have been discouraged to consume vitamin-K-rich foods, such as green leafy vegetables.The objective of this study is to summarize the current evidence supporting the putative interaction between dietary vitamin K intake and changes in INR with the VKAs.Data sources are MEDLINE via PubMed and Cochrane database.All clinical studies investigating the relationship between dietary vitamin K and measures of anticoagulation were included. We excluded all studies of supplementation of vitamin K alone.We performed a systematic review of the literature up to October 2015, searching for a combination of "food," "diet," "vitamin K," "phylloquinone," "warfarin," "INR," "coagulation," and "anticoagulant."Two dietary interventional trials and 9 observational studies were included. We found conflicting evidence on the effect of dietary intake of vitamin K on coagulation response. Some studies found a negative correlation between vitamin K intake and INR changes, while others suggested that a minimum amount of vitamin K is required to maintain an adequate anticoagulation. Median dietary intake of vitamin K1 ranged from 76 to 217 μg/day among studies, and an effect on coagulation may be detected only for high amount of vitamin intake (>150 μg/day).Most studies included patients with various indications for VKAs therapy, such as atrial fibrillation, prosthetic heart valves, and venous thromboembolism. Thus, INR target was dishomogeneous and no subanalyses for specific populations or different anticoagulants were conducted. Measures used to evaluate anticoagulation stability were variable.The available evidence does not support current advice to modify dietary habits when starting therapy with VKAs. Restriction of dietary vitamin K intake does not seem to be a valid strategy to improve anticoagulation quality with VKAs. It would be, perhaps, more relevant to maintain stable dietary habit, avoiding wide changes in the intake of vitamin K.
SN  - 0025-7974
AD  - From the Center of Atherothrombosis (FV, PP, DP), I Medical Clinic, Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Umberto I Policlinic of Rome, Rome, Italy; and Centre for Cardiovascular Sciences (GYHL), City Hospital, University of Birmingham, Birmingham, UK
U2  - PMID: 26962786.
DO  - 10.1097/MD.0000000000002895
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=113659867&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105188427
T1  - Introducing the AFib Support Team...Bradley P. Knight, MD, FACC, FHRS... Kathy Berra, MSN, ANP, FAANP...Alexis Abramson, PhD... Janie Clark, MA
AU  - Elrod J
Y1  - 2010/03//2010 Mar
N1  - Accession Number: 105188427. Language: English. Entry Date: 20100702. Revision Date: 20150711. Publication Type: Journal Article; interview; pictorial. Journal Subset: Allied Health; Biomedical; USA. Special Interest: Laboratory Diagnosis. NLM UID: 101174623. 
KW  - Atrial Fibrillation
KW  - Corporations
KW  - Health Information
KW  - Marketing
KW  - Multidisciplinary Care Team
KW  - Patient Education
KW  - Program Implementation
KW  - Support, Psychosocial
KW  - Teamwork
KW  - Age Factors
KW  - Anniversaries and Special Events
KW  - Atrial Fibrillation -- Diagnosis
KW  - Atrial Fibrillation -- Psychosocial Factors
KW  - Atrial Fibrillation -- Therapy
KW  - Cardiology
KW  - Decision Making
KW  - Drugs, Prescription -- Adverse Effects
KW  - Electrophysiology
KW  - Exercise
KW  - Geriatricians
KW  - Life Style
KW  - Nurses
KW  - Perception -- Methods
KW  - Personal Trainers
KW  - Personnel Recruitment
KW  - Physician Attitudes
KW  - Physician's Role
KW  - Physicians
KW  - Professional-Patient Relations
KW  - Role
KW  - Safety
KW  - Team Building
KW  - Teamwork -- Methods
SP  - 30
EP  - 32
JO  - EP Lab Digest
JF  - EP Lab Digest
JA  - EP LAB DIGEST
VL  - 10
IS  - 3
CY  - Malvern, Pennsylvania
PB  - HMP Communications
SN  - 1535-2226
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105188427&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108187308
T1  - June newswire.
Y1  - 2012/06//2012 Jun
N1  - Accession Number: 108187308. Language: English. Entry Date: 20120608. Revision Date: 20150712. Publication Type: Journal Article. Journal Subset: Consumer Health; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Consumer Health. NLM UID: 9802902. 
KW  - Arthritis, Rheumatoid -- Complications
KW  - Aspirin -- Adverse Effects
KW  - Atrial Fibrillation -- Risk Factors
KW  - Berries -- Therapeutic Use
KW  - Botulinum Toxins -- Therapeutic Use
KW  - Cognition Disorders -- Prevention and Control
KW  - Information Resources
KW  - Macular Degeneration -- Risk Factors
KW  - Manipulation, Orthopedic
KW  - Neck Pain -- Therapy
KW  - Obesity -- Prevention and Control
KW  - Overactive Bladder -- Drug Therapy
KW  - Serial Publications
KW  - Walking
SP  - 2
EP  - 5
JO  - Johns Hopkins Medical Letter: Health After 50
JF  - Johns Hopkins Medical Letter: Health After 50
JA  - JOHNS HOPKINS MED LETT HEALTH AFTER 50
VL  - 24
IS  - 4
CY  - New York, New York
PB  - Scientific American
SN  - 1042-1882
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108187308&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109709755
T1  - Knowledge regarding oral anticoagulation therapy among patients with stroke and those at high risk of thromboembolic events.
AU  - Alphonsa, Annu
AU  - Sharma, Kamlesh K
AU  - Sharma, Gautam
AU  - Bhatia, Rohit
Y1  - 2015/03//
N1  - Accession Number: 109709755. Language: English. Entry Date: 20150923. Revision Date: 20160317. Publication Type: journal article. Journal Subset: Biomedical; Double Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9111633. 
SP  - 668
EP  - 672
JO  - Journal of Stroke & Cerebrovascular Diseases
JF  - Journal of Stroke & Cerebrovascular Diseases
JA  - J STROKE CEREBROVASC DIS
VL  - 24
IS  - 3
CY  - Philadelphia, Pennsylvania
PB  - W B Saunders
AB  - Background: Apart from atrial fibrillation, indications for oral anticoagulation common in our clinical practice include rheumatic heart disease and mechanical heart valve replacement. Evaluation of current patient knowledge regarding oral anticoagulation therapy (OAT) is the first step in improving the quality of anticoagulation therapy and patient care. The aim of the present study was to assess the knowledge regarding OAT among patients with stroke and those at high risk of thromboembolic events in a tertiary care hospital in India.Methods: A descriptive cross-sectional design was used; 240 patients on OAT because of various indications (mechanical heart valve replacement, rheumatic heart disease, atrial fibrillation, and stroke) attending the neurology and cardiology outpatient clinics and inpatient services were recruited. A structured self-developed questionnaire was used to assess the knowledge in these patients.Results: Most patients (62.9%) were ignorant about the target prothrombin time/international normalized ratio (PT/INR) levels with only 30% having their recent INR within the target range; 50% of the patients had a poor knowledge score, and the knowledge gap was most prominent in the domains of dietary interactions followed by drug interactions, adverse effects, and PT/INR monitoring. Knowledge score also had a significant association with gender, education, monthly income, and place of residence (P < .05).Conclusion: Patient's knowledge about OAT was suboptimal. The findings support the need for educational interventions to improve the knowledge regarding OAT and, thereby, achieve an appropriate and safe secondary prevention of stroke.
SN  - 1052-3057
U2  - PMID: 25577429.
DO  - 10.1016/j.jstrokecerebrovasdis.2014.11.007
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105256936
T1  - Late-breaking news.
Y1  - 2009/12//2009 Dec
N1  - Accession Number: 105256936. Language: English. Entry Date: 20100108. Revision Date: 20150711. Publication Type: Journal Article; brief item. Journal Subset: Consumer Health; USA. Special Interest: Consumer Health. NLM UID: 9891730. 
KW  - Atrial Fibrillation -- Complications
KW  - Attitude
KW  - Dementia
KW  - Fluid Intake
KW  - Gout -- Prevention and Control
KW  - Longevity
SP  - 1
EP  - 1
JO  - Bottom Line Health
JF  - Bottom Line Health
JA  - BOTTOM LINE HEALTH
VL  - 23
IS  - 12
CY  - Greenwich, Connecticut
PB  - Health Confidential
SN  - 1092-0129
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105925086
T1  - Left ventricular geometry and renal function in hypertensive patients with diastolic heart failure.
AU  - Afshinnia F
AU  - Spitalewitz S
AU  - Chou SY
AU  - Gunsburg DZ
AU  - Chadow HL
Y1  - 2007/02//
N1  - Accession Number: 105925086. Language: English. Entry Date: 20080111. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 8110075. 
KW  - Blood Pressure -- Physiology
KW  - Heart Failure -- Physiopathology
KW  - Hypertension -- Physiopathology
KW  - Hypertrophy, Left Ventricular -- Physiopathology
KW  - Kidney -- Physiology
KW  - Aged
KW  - Aged, 80 and Over
KW  - Cardiovascular System Physiology
KW  - Cross Sectional Studies
KW  - Diastole -- Physiology
KW  - Female
KW  - Heart Failure -- Complications
KW  - Hypertension -- Complications
KW  - Hypertrophy, Left Ventricular -- Complications
KW  - Kidney Function Tests
KW  - Male
KW  - Middle Age
KW  - Prospective Studies
KW  - Human
SP  - 227
EP  - 236
JO  - American Journal of Kidney Diseases
JF  - American Journal of Kidney Diseases
JA  - AM J KIDNEY DIS
VL  - 49
IS  - 2
CY  - Philadelphia, Pennsylvania
PB  - W B Saunders
AB  - BACKGROUND: The objective is to define the relationship between cardiac geometry and renal function in hypertensive subjects with and without diastolic heart failure (DHF). METHODS: This is a prospective observational study in a tertiary-care teaching institute in a 15-month period of consecutive hospitalized hypertensive patients. Patients on dialysis therapy or with atrial fibrillation, systolic heart failure, gross proteinuria, and glomerular diseases were excluded. Two-dimensional echocardiography was performed and stable glomerular filtration rate (GFR) was calculated by using the Modification of Diet in Renal Disease formula. Patients were classified into stage 1 to 5 chronic kidney disease (CKD). RESULTS: Five hundred forty hypertensive patients were separated into 2 groups: 286 patients with DHF and 254 patients without DHF. Mean age was 69.1 +/- 13.7 (SD) years in general. In patients with DHF, from stages 1 to 5 CKD, there was a significant graded increase in left ventricular mass index (from 117.3 to 162.4 g/m(2)) and relative wall thickness (from 0.42 to 0.52) and a significant graded decrease in aortic cusp separation (from 1.85 to 1.55 cm). Among echocardiographic variables, left ventricular mass index and relative wall thickness were associated inversely and aortic cusp separation was associated directly with GFR. In the absence of DHF, only left ventricular mass index was associated inversely with GFR, suggesting a prominent role of aortic cusp separation and relative wall thickness in the variability in GFR in patients with DHF through a hemodynamic disturbance. CONCLUSION: Hemodynamic alterations have a prominent role in the variability of GFR in patients with CKD with DHF. Adverse cardiac geometry is linked to the severity of CKD in hypertensive patients, raising the possibility of preserving both cardiac and renal function by means of hypertension control. Copyright © 2007 by the National Kidney Foundation, Inc.
SN  - 0272-6386
U2  - PMID: 17261425.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109646793
T1  - Letter by González-Salvado et al Regarding Article, 'Extravirgin Olive Oil Consumption Reduces Risk of Atrial Fibrillation: The PREDIMED (Prevención con Dieta Mediterránea) Trial'.
AU  - González-Salvado, Violeta
AU  - Raposeiras-Roubín, Sergio
AU  - González-Juanatey, José Ramón
Y1  - 2015/09/08/
N1  - Accession Number: 109646793. Language: English. Entry Date: 20150923. Revision Date: 20150923. Publication Type: Journal Article. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0147763. 
SP  - e139
EP  - e139
JO  - Circulation
JF  - Circulation
JA  - CIRCULATION
VL  - 132
IS  - 10
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
SN  - 0009-7322
U2  - PMID: 26354788.
DO  - 10.1161/CIRCULATIONAHA.114.012242
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104575960
T1  - Lifestyle and atrial fibrillation.
AU  - Mattioli AV
Y1  - 2011/07//
N1  - Accession Number: 104575960. Language: English. Entry Date: 20120323. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice. NLM UID: 101182328. 
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Mediterranean Diet
KW  - Life Style
KW  - Animals
KW  - Atrial Fibrillation -- Etiology
KW  - Health Behavior
KW  - Obesity -- Complications
KW  - Risk Factors
KW  - Ventricular Dysfunction -- Complications
SP  - 895
EP  - 902
JO  - Expert Review of Cardiovascular Therapy
JF  - Expert Review of Cardiovascular Therapy
JA  - EXPERT REV CARDIOVASC THER
VL  - 9
IS  - 7
CY  - Philadelphia, Pennsylvania
PB  - Taylor & Francis Ltd
SN  - 1477-9072
AD  - Department of Biomedical Science, University of Modena and RE, Via del Pozzo 71, Modena 41100, Italy. annavittoria.mattioli@unimore.it.
U2  - PMID: 21809971.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107507891
T1  - Lone atrial fibrillation: it needn't slow down an active patient.
AU  - Cantwell JD
AU  - Lammert S
AU  - Kessler C
Y1  - 1991/08//1991 Aug
N1  - Accession Number: 107507891. Language: English. Entry Date: 19911001. Revision Date: 20150712. Publication Type: Journal Article; case study; tables/charts. Journal Subset: Allied Health; Peer Reviewed; USA. NLM UID: 0427461. 
KW  - Atrial Fibrillation
KW  - Exercise
KW  - Adult
KW  - Middle Age
KW  - Male
SP  - 70
EP  - 82
JO  - Physician & Sportsmedicine
JF  - Physician & Sportsmedicine
JA  - PHYSICIAN SPORTSMED
VL  - 19
IS  - 8
CY  - Philadelphia, Pennsylvania
PB  - Taylor & Francis Ltd
SN  - 0091-3847
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105433803
T1  - Long term conditions.
Y1  - 2009/09/08/2009 Sep 8-14
N1  - Accession Number: 105433803. Language: English. Entry Date: 20091009. Revision Date: 20150711. Publication Type: Journal Article; brief item; pictorial. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 0423236. 
KW  - Adolescence
KW  - AIDS Dementia Complex -- Diagnosis
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Child
KW  - Chronic Disease -- Therapy
KW  - Chronic Pain -- Therapy
KW  - Diabetes Mellitus -- Therapy
KW  - Exercise
KW  - Functional Status
KW  - Irbesartan -- Therapeutic Use
KW  - Low Back Pain -- Therapy
KW  - Practice Guidelines
KW  - Yoga
SP  - 6
EP  - 7
JO  - Nursing Times
JF  - Nursing Times
JA  - NURS TIMES
VL  - 105
IS  - 35
PB  - EMAP Healthcare
SN  - 0954-7762
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103562789
T1  - Long-Term Weight Loss Rivals Medications and Ablation for AF Rhythm Control.
AU  - Pellegrini, Cara
Y1  - 2015/07//
N1  - Accession Number: 103562789. Language: English. Entry Date: 20150707. Revision Date: 20150707. Publication Type: Article. Original Study: Pathak Rajeev K, Middeldorp Melissa E, Meredith Megan, Mehta Abhinav B, Mahajan Rajiv, Wong Christopher X, et al. Long-Term Effect of Goal-Directed Weight Management in an Atrial Fibrillation Cohort: A Long-Term Follow-Up Study (LEGACY). (J AM COLL CARDIOL) May2015; 65 (20): 2159-2169. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9880022. 
KW  - Weight Loss
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Catheter Ablation
KW  - Atrial Fibrillation -- Surgery
KW  - Heart Rate
KW  - Obesity -- Complications
KW  - Weight Control
KW  - Risk Factors
SP  - 53
EP  - 54
JO  - Clinical Cardiology Alert
JF  - Clinical Cardiology Alert
JA  - CLIN CARDIOL ALERT
VL  - 34
IS  - 7
CY  - Atlanta, Georgia
PB  - AHC Media LLC
SN  - 0741-4218
AD  - Assistant Professor of Medicine, UCSF
AD  - Cardiology Division, Electrophysiology Section, San Francisco VA Medical Center
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109813462
T1  - Long-Term Weight Loss Rivals Medications and Ablation for AF Rhythm Control.
AU  - Pellegrini, Cara
Y1  - 2015/07//
N1  - Accession Number: 109813462. Language: English. Entry Date: 20150707. Revision Date: 20150923. Publication Type: Journal Article; abstract; commentary. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9880022. 
KW  - Weight Loss
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Catheter Ablation
KW  - Atrial Fibrillation -- Surgery
KW  - Heart Rate
KW  - Obesity -- Complications
KW  - Weight Control
KW  - Risk Factors
SP  - 53
EP  - 54
JO  - Clinical Cardiology Alert
JF  - Clinical Cardiology Alert
JA  - CLIN CARDIOL ALERT
VL  - 34
IS  - 7
CY  - Atlanta, Georgia
PB  - AHC Media LLC
SN  - 0741-4218
AD  - Assistant Professor of Medicine, UCSF; Cardiology Division, Electrophysiology Section, San Francisco VA Medical Center
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109834573
T1  - Long-term Weight Loss Rivals Medications and Ablation for AF Rhythm Control.
AU  - Pellegrini, Cara
Y1  - 2015/08/15/
N1  - Accession Number: 109834573. Language: English. Entry Date: 20150819. Revision Date: 20150923. Publication Type: Journal Article; abstract; commentary. Original Study: Rathak RK, et al. Long-term effect of goal-directed weight management in an atrial fibrillation cohort: A long-term follow-up study (LEGACY). J Am Coll Cardiol 2015; 65: 2159-2169. Journal Subset: Biomedical; USA. Special Interest: Critical Care; Public Health. NLM UID: 8003602. 
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Weight Loss
KW  - Weight Control
KW  - Catheter Ablation
KW  - Antiarrhythmia Agents
KW  - Obesity -- Complications
KW  - Atrial Fibrillation -- Risk Factors
KW  - Body Mass Index
SP  - 116
EP  - 117
JO  - Internal Medicine Alert
JF  - Internal Medicine Alert
JA  - INTERN MED ALERT
VL  - 37
IS  - 15
CY  - Atlanta, Georgia
PB  - AHC Media LLC
SN  - 0195-315X
AD  - Assistant Professor of Medicine, UCSF, Cardiology Division, Electrophysiology Section, San Francisco VA Medical Center
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107801042
T1  - Low fasting plasma insulin is associated atrial fibrillation in men from a cohort study - the Malmö preventive project.
AU  - Johnson, Linda Sb
AU  - Juhlin, Tord
AU  - Engström, Gunnar
AU  - Nilsson, Peter M
Y1  - 2014/01//
N1  - Accession Number: 107801042. Language: English. Entry Date: 20150206. Revision Date: 20150712. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; UK & Ireland. NLM UID: 100968539. 
KW  - Atrial Fibrillation -- Epidemiology
KW  - Fasting
KW  - Insulin -- Blood
KW  - Adult
KW  - Atrial Fibrillation -- Blood
KW  - Atrial Fibrillation -- Diagnosis
KW  - Biological Markers -- Blood
KW  - Blood Glucose -- Metabolism
KW  - Body Mass Index
KW  - Female
KW  - Prospective Studies
KW  - Human
KW  - Incidence
KW  - Male
KW  - Cox Proportional Hazards Model
KW  - Risk Factors
KW  - Sex Factors
KW  - Sweden
KW  - Time Factors
SP  - 107
EP  - 107
JO  - BMC Cardiovascular Disorders
JF  - BMC Cardiovascular Disorders
JA  - BMC CARDIOVASC DISORD
VL  - 14
IS  - 1
PB  - BioMed Central
SN  - 1471-2261
AD  - Department of Clinical Sciences, Lund University, Skåne University Hospital, Inga-Marie Nilssons väg 49, 20502 Malmö, Sweden. linda.johnson@med.lu.se.
U2  - PMID: 25150967.
DO  - 10.1186/1471-2261-14-107
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105721988
T1  - Management of heart failure in elderly people.
AU  - Imazio M
AU  - Cotroneo A
AU  - Gaschino G
AU  - Chinaglia A
AU  - Gareri P
AU  - Lacava R
AU  - Voci TD
AU  - Trinchero R
Y1  - 2008/02//
N1  - Accession Number: 105721988. Language: English. Entry Date: 20080523. Revision Date: 20150711. Publication Type: Journal Article; review; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Gerontologic Care. NLM UID: 9712381. 
KW  - Heart Failure -- Therapy -- In Old Age
KW  - Accidental Falls
KW  - Adrenergic Beta-Antagonists -- Therapeutic Use
KW  - Aged
KW  - Aging
KW  - Arthritis -- Complications
KW  - Atrial Fibrillation -- Complications
KW  - Comorbidity
KW  - Coronary Arteriosclerosis -- Surgery
KW  - Defibrillators, Implantable
KW  - Dementia -- Complications
KW  - Depression -- Complications
KW  - Diuretics -- Therapeutic Use
KW  - Frail Elderly
KW  - Heart Failure -- Diagnosis
KW  - Heart Failure -- Drug Therapy
KW  - Heart Failure -- Physiopathology
KW  - Heart Failure -- Risk Factors
KW  - Heart Failure -- Symptoms
KW  - Hospitalization
KW  - Hypotension
KW  - Incontinence -- Complications
KW  - Kidney Diseases -- Complications
KW  - Lung Diseases -- Complications
KW  - Multidisciplinary Care Team
KW  - Nervous System Diseases -- Complications
KW  - Nutrition Disorders -- Complications
KW  - Pacemaker, Artificial
KW  - Palliative Care
KW  - Patient Admission
KW  - Patient Education
KW  - Physical Activity
KW  - Physical Mobility
KW  - Self Care
KW  - Smoking Cessation
KW  - Urinary Incontinence
KW  - Weight Control
SP  - 270
EP  - 280
JO  - International Journal of Clinical Practice
JF  - International Journal of Clinical Practice
JA  - INT J CLIN PRACT
VL  - 62
IS  - 2
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Aims: To review currently available knowledge on presentation, clinical features and management of heart failure (HF) in elderly people. Methods: To review currently available evidence, we performed a thorough search of several evidence-based sources of information, including Cochrane Database of Systematic Reviews, Clinical Evidence, Evidence-based guidelines from National Guidelines Clearinghouse and a comprehensive MEDLINE search with the MeSH terms: 'heart failure', 'elderly' and 'management'. Results: A number of features of ageing may predispose elderly people to HF, and may impair the ability to respond to injuries. Another hallmark of elderly patients is the increasing prevalence of multiple coexisting chronic conditions and geriatric syndromes that may complicate the clinical presentation and evolution of HF. Although diagnosis may be challenging, because atypical symptoms and presentations are common, and comorbid conditions may mimic or complicate the clinical picture, diagnostic criteria do not change in elderly people. Drug treatment is not significantly different from that recommended in younger patients, and largely remains empiric, because clinical trials have generally excluded elderly people and patients with comorbid conditions. Disease management programmes may have the potential to reduce morbidity and mortality for patients with HF. Conclusions: Heart failure is the commonest reason for hospitalisation and readmission among older adults. HF shows peculiar features in elderly people, and is usually complicated by comorbidities, presenting a significant financial burden worldwide, nevertheless elderly people have been generally excluded from clinical trials, and thus management largely remains empiric and based on evidence from younger age groups.
SN  - 1368-5031
AD  - Cardiology Department, Maria Vittoria Hospital, Torino, Italy
U2  - PMID: 18070044.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107215712
T1  - Managing atrial fibrillation in active patients and athletes.
AU  - Reiss RA
A2  - Christie DM
Y1  - 1999/03//
N1  - Accession Number: 107215712. Language: English. Entry Date: 19991001. Revision Date: 20150820. Publication Type: Journal Article; case study; CEU; exam questions; tracings. Journal Subset: Allied Health; Peer Reviewed; USA. NLM UID: 0427461. 
KW  - Atrial Fibrillation
KW  - Exercise
KW  - Education, Continuing (Credit)
KW  - Atrial Fibrillation -- Diagnosis
KW  - Atrial Fibrillation -- Therapy
KW  - Electrocardiography
KW  - Adult
KW  - Middle Age
KW  - Aged
KW  - Aged, 80 and Over
KW  - Male
KW  - Female
SP  - 73
EP  - 80
JO  - Physician & Sportsmedicine
JF  - Physician & Sportsmedicine
JA  - PHYSICIAN SPORTSMED
VL  - 27
IS  - 3
CY  - Philadelphia, Pennsylvania
PB  - Taylor & Francis Ltd
T3  - Internal medicine series
AB  - Atrial fibrillation in young or middle-aged active patients can often be managed with medication. Evaluation should address associated conditions and predisposing factors such as idiopathic hypertrophic subaortic stenosis, Wolff-Parkinson-White syndrome, congenital heart disease, hyperthyroidism, excess alcohol or other drug use, and exercise-induced catecholamine release. Diagnostic studies may include an ECG, 24-hour Holter or event monitoring, exercise treadmill testing, stress echocardiography, electrophysiologic studies, and laboratory testing. Electrocardioversion provides rapid, predictable treatment, but ablation therapy is sometimes needed.
SN  - 0091-3847
AD  - The Westchester Medical Group Center for Heart and Health, 8540 S Sepulveda Blvd, Ste 118, Los Angeles, CA 90045; e-mail: chh@danielfreeman.org
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104575698
T1  - Managing Hyperkalaemia In Heart Failure Patients--A Review Of A Case Study At The Komfo Anokye Teaching Hospital, Kumasi, Ghana.
AU  - Anane, Charles
Y1  - 2010/11//
N1  - Accession Number: 104575698. Language: English. Entry Date: 20120227. Revision Date: 20150711. Publication Type: Journal Article; case study; tables/charts. Journal Subset: Biomedical; Editorial Board Reviewed; Peer Reviewed; USA. NLM UID: 101207289. 
KW  - Hyperkalemia -- Etiology
KW  - Heart Failure -- Complications
KW  - Cardiovascular Agents -- Adverse Effects
KW  - Heart Failure -- Drug Therapy
KW  - Ghana
KW  - Hyperkalemia -- Blood
KW  - Hyperkalemia -- Mortality
KW  - Hyperkalemia -- Symptoms
KW  - Hyperkalemia -- Therapy
KW  - Adult
KW  - Female
SP  - 1
EP  - 1
JO  - Internet Journal of Cardiology
JF  - Internet Journal of Cardiology
JA  - INTERNET J CARDIOL
VL  - 9
IS  - 2
CY  - Sugar Land, Texas
PB  - Internet Scientific Publications LLC
AB  - PURPOSE: Angiotensin-converting-enzyme (ACE) inhibitors, Angiotensin-receptor blockers (ARBs), Aldosterone-antagonists and recently Beta-adrenergic blockers are all neurohormonal blocking agents of the renin-angiotensin-aldosterone system. These drugs are used in clinical practice to treat heart failure. A side effect of such therapy is the development of hyperkalaemia.Determination of the incidence of clinical important hyperkalaemia in heart failure patients treated with the above recommended therapy forms the basis of this overview.SETTING: The Medicine Directorate of Komfo Anokye Teaching Hospital, KATH, Kumasi, Ghana, West Africa.KATH is located in Kumasi, the capital of Ashanti Region in Ghana. The geographical location of the 1000-bed teaching hospital, the road network of the country and commercial nature of Kumasi make the hospital accessible to all areas that share boundaries with the Region.The Directorate of Medicine has 220 beds and the patients admitted at the wards aged from 13 years and above. The directorate runs emergency service 24 hours, seven days a week. Referrals from regional hospitals, district hospitals, general practitioners and private clinics are admitted to the medical wards through the emergency unit.A case study involving a 32-year old female who presented with breathlessness, dizziness and easy fatiguability for 2-day duration was admitted at the medical ward of KATH. A full blood count revealed the following; Sodium 145mmol/L (normal range 135-145mmole/l) and Serum Potassium 6.5mmole/l (normal range 3.5-5.4mmole/l). The woman was diagnosed as having heart failure NYHA IV, fast Atrial Fibrillation, with severe rheumatic mitrial regurgitation and mitrial stenosis. The high serum potassium was described as moderate hyperkalaemia.Conclusion: Heart failure patients undergoing treatment must have their full blood count investigated before initiation of therapy and two weeks after to monitor levels of electrolytes. High serum sodium will cause fluid retention and aggravate generalized oedema. Potassium level >5.5mmol/l is likely to cause significant hyperkalaemia. Patients' medical history must be reviewed and appropriate treatment given.
SN  - 1528-834X
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104228678
T1  - Marine n-3 fatty acids in adipose tissue and development of atrial fibrillation: a Danish cohort study.
AU  - Rix, Thomas Andersen
AU  - Joensen, Albert Marni
AU  - Riahi, Sam
AU  - Lundbye-Christensen, Søren
AU  - Overvad, Kim
AU  - Schmidt, Erik Berg
Y1  - 2013/10/15/
N1  - Accession Number: 104228678. Language: English. Entry Date: 20131129. Revision Date: 20150711. Publication Type: Journal Article; research; randomized controlled trial. Journal Subset: Biomedical; Blind Peer Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. NLM UID: 9602087. 
KW  - Adipose Tissue
KW  - Atrial Fibrillation -- Epidemiology
KW  - Dietary Fats -- Pharmacodynamics
KW  - Fatty Acids, Omega-3 -- Analysis
KW  - Population Surveillance -- Methods
KW  - Seafood
KW  - Atrial Fibrillation -- Etiology
KW  - Atrial Fibrillation -- Metabolism
KW  - Biological Markers
KW  - Biopsy
KW  - Denmark
KW  - Fatty Acids, Omega-3 -- Metabolism
KW  - Female
KW  - Prospective Studies
KW  - Human
KW  - Incidence
KW  - Male
KW  - Middle Age
KW  - Retrospective Design
SP  - 1519
EP  - 1524
JO  - Heart
JF  - Heart
JA  - HEART
VL  - 99
IS  - 20
PB  - BMJ Publishing Group
AB  - OBJECTIVE: Consumption of fish and marine n-3 polyunsaturated fatty acids (PUFA) may be associated with a lower risk of atrial fibrillation (AF), but results have been inconsistent. The aim was to investigate this further by measurements of marine n-3 PUFA in adipose tissue. DESIGN: Cohort study. SETTING: A total of 57 053 Danish participants 50-64 years of age were enrolled into the Diet, Cancer and Health Cohort Study. PATIENTS: A randomly drawn subcohort of 3440 participants with available data from baseline adipose tissue biopsies. INTERVENTIONS: Exposure was the adipose tissue content of marine n-3 PUFA, which reflects the endogenous exposure and is also an objective marker of the long-term dietary intake. MAIN OUTCOME MEASURES: Incident AF during follow-up. RESULTS: 179 cases of AF occurred over 13.6 years. Multivariate, sex-stratified Cox proportional hazards regression analyses using cubic splines showed a monotonic, negative, dose-response trend, but not statistically significant association, between total marine n-3 PUFA in adipose tissue and incident AF. A similar trend towards a lower risk of AF was seen in the second (HR 0.87, 95% CI 0.60 to 1.24) and third tertiles (HR 0.77, 95% CI 0.53 to 1.10) of marine n-3 PUFA compared with the lowest tertile. Similar trends, but also not statistically significant, were found separately for eicosapentaenoic, docosahexaenoic and docosapentaenoic acids. CONCLUSIONS: There was no statistically significant association between the content of marine n-3 PUFA in adipose tissue and the development of AF; however, data showed a monotonic, negative dose-response trend suggestive of a negative association.
SN  - 1355-6037
AD  - Department of Cardiology, Aalborg AF Study Group, Center for Cardiovascular Research, Aalborg University Hospital, , Aalborg, Denmark.
U2  - PMID: 23945170.
DO  - 10.1136/heartjnl-2013-304385
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109834916
T1  - Mediterranean diet reduces thromboxane A2 production in atrial fibrillation patients.
AU  - Pignatelli, Pasquale
AU  - Pastori, Daniele
AU  - Farcomeni, Alessio
AU  - Nocella, Cristina
AU  - Bartimoccia, Simona
AU  - Vicario, Tommasa
AU  - Bucci, Tommaso
AU  - Carnevale, Roberto
AU  - Violi, Francesco
Y1  - 2015/10//
N1  - Accession Number: 109834916. Language: English. Entry Date: 20150821. Revision Date: 20150923. Publication Type: Journal Article; research. Journal Subset: Allied Health; Biomedical; Continental Europe; Double Blind Peer Reviewed; Europe; Peer Reviewed. Special Interest: Nutrition. NLM UID: 8309603. 
KW  - Atrial Fibrillation -- Complications
KW  - Mediterranean Diet
KW  - Platelet Activation
KW  - Thromboxanes -- Urine
KW  - Italy
KW  - Patient Compliance
KW  - Prospective Studies
KW  - Questionnaires
KW  - P-Value
KW  - Middle Age
KW  - Aged
KW  - Female
KW  - Male
KW  - Human
SP  - 899
EP  - 903
JO  - Clinical Nutrition
JF  - Clinical Nutrition
JA  - CLIN NUTR
VL  - 34
IS  - 5
CY  - New York, New York
PB  - Elsevier Science
AB  - Summary Background & aims Platelet activation plays a major role in cardiovascular events (CVEs). Mediterranean diet (Med-Diet) reduces the incidence of stroke and myocardial infarction but it is still unclear if it affects platelet activation. Aim of the study was to evaluate the effect of Med-Diet on the urinary excretion of 11-dehydro-thromboxane (Tx) B2, a marker of in vivo platelet activation, in patients with atrial fibrillation (AF). Methods Prospective observational cohort study including 801 non-valvular AF patients on chronic treatment with warfarin/acenocumarol referring to I Medical Clinic – Atherothrombosis Center of Sapienza University of Rome, Italy, from February 2008 to December 2013. Adherence to Med-Diet was evaluated by a short nine-items dietary questionnaire. Urinary excretion of 11-dehydro-TxB2 was measured in all patients. Results Mean follow-up was 33.9 (±19.8) months, yielding 2223 patient/year of observation. Mean age of patients was 73.3 (±8.9) years, 43.7% were female. Median value of urinary TxB2 was 105.5 [60.0–190.0] ng/mg creatinine. We found a significant inverse correlation between total Med-Diet score and 11-dehydro-TxB2 values (Rs: −0.356, p < 0.001). In a multivariable stepwise linear regression analysis, history of stroke/TIA ( β = 0.146, p = 0.003), olive oil ( β = −0.130, p = 0.007), wine ( β = −0.102, p = 0.036) and antiplatelet drugs ( β = −0.098, p = 0.045) were independently associated to 11-dehydro-TxB2. We found no differences in the rate of ischemic or bleeding events across tertiles of Med-Diet score during follow-up. Conclusions Med-Diet adherence is inversely associated to urinary excretion of 11-dehydro-TxB2, suggesting that Med-Diet may favorably affect platelet function in AF patients. Clinical Trial Registration ClinicalTrials.gov NCT01882114 .
SN  - 0261-5614
AD  - I Clinica Medica, Atherothrombosis Center, Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy
AD  - Department of Public Health and Infectious Diseases, “Sapienza” University of Rome, Rome, Italy
U2  - PMID: 25288566.
DO  - 10.1016/j.clnu.2014.09.011
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ER  - 

TY  - JOUR
ID  - 104077630
T1  - Mediterranean diet, lower iron stores and atrial fibrillation...Nutr Metab Cardiovasc Dis. 2013 Feb;23(2):115-21
AU  - Mascitelli, L
AU  - Goldstein, M R
Y1  - 2013/06//
N1  - Accession Number: 104077630. Language: English. Entry Date: 20140214. Revision Date: 20150710. Publication Type: Journal Article; commentary; letter. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. Special Interest: Nutrition. NLM UID: 9111474. 
KW  - Antioxidants -- Administration and Dosage
KW  - Atrial Fibrillation -- Diet Therapy
KW  - Mediterranean Diet
KW  - Patient Compliance
KW  - Female
KW  - Male
SP  - e28
EP  - 9
JO  - Nutrition, Metabolism & Cardiovascular Diseases
JF  - Nutrition, Metabolism & Cardiovascular Diseases
JA  - NUTR METAB CARDIOVASC DIS
VL  - 23
IS  - 6
CY  - New York, New York
PB  - Elsevier Science
SN  - 0939-4753
AD  - Comando Brigata Alpina 'Julia', Medical Service, 8 Via S. Agostino, Udine 33100, Italy. Electronic address: lumasci@libero.it.
U2  - PMID: 23582310.
DO  - 10.1016/j.numecd.2013.02.005
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 106183773
T1  - Metabolic risk factors for stroke and transient ischemic attacks in middle-aged men: a community-based study with long-term follow-up.
AU  - Wiberg B
AU  - Sundström J
AU  - Arnlöv J
AU  - Terént A
AU  - Vessby B
AU  - Zethelius B
AU  - Lind L
Y1  - 2006/12//2006 Dec
N1  - Accession Number: 106183773. Language: English. Entry Date: 20071102. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Allied Health; Biomedical; Peer Reviewed; USA. Special Interest: Physical Therapy. NLM UID: 0235266. 
KW  - Cerebral Ischemia, Transient -- Blood
KW  - Cerebral Ischemia, Transient -- Epidemiology
KW  - Stroke -- Blood
KW  - Stroke -- Epidemiology
KW  - Residence Characteristics
KW  - Aged
KW  - Aged, 80 and Over
KW  - Dietary Fats -- Adverse Effects
KW  - Lipoproteins -- Blood
KW  - Male
KW  - Middle Age
KW  - Prospective Studies
KW  - Risk Factors
KW  - Time Factors
KW  - Human
SP  - 2898
EP  - 2903
JO  - Stroke (00392499)
JF  - Stroke (00392499)
JA  - STROKE
VL  - 37
IS  - 12
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - BACKGROUND AND PURPOSE: The impact of lipometabolic and glucometabolic disturbances on stroke incidence remains to be characterized in detail. We investigated relations of a comprehensive panel of baseline lipometabolic and glucometabolic variables to incident fatal and nonfatal stroke or transient ischemic attack (TIA), and stroke subtypes. METHODS: A community-based prospective study of 2313 middle-aged men invited to a health survey at age 50. RESULTS: During a follow-up of up to 32 years, 421 developed stroke or TIA. In Cox proportional hazards analyses adjusting for treatment with cardiovascular drugs at baseline, 1-standard deviation increases in body mass index, systolic and diastolic blood pressures, serum proinsulin, and lipoprotein(a) were associated with 11 to 35% increased risk for subsequent stroke/TIA. Electrocardiographic left ventricular hypertrophy and smoking were also associated with a higher risk for stroke/TIA. Essentially the same variables were related to brain infarction/TIA. Higher proportions of palmitic (16:0), palmitoleic (16:1), and oleic acid (18:1) in cholesterol esters were associated with an increased risk, whereas a higher proportion of linoleic acid (18:2 n-6) was protective against stroke/TIA. Further adjusting all models also for hypertension, diabetes, the metabolic syndrome, serum cholesterol, atrial fibrillation, cardiovascular disease, smoking, and physical activity, essentially the same pattern was observed. CONCLUSIONS: Indices of an unhealthy dietary fat intake and a high serum lipoprotein (a) level predicted fatal and nonfatal stroke/TIA independently of established risk factors in a community-based sample of middle-aged men followed for 32 years.
SN  - 0039-2499
AD  - Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala Science Park, SE-751 85 Uppsala, Sweden. bernice.wiberg@akademiska.se
U2  - PMID: 17053177.
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 110474428
T1  - Metabolic syndrome, atrial fibrillation, and stroke: Tackling an emerging epidemic.
AU  - Hajhosseiny, Reza
AU  - Matthews, Gareth K.
AU  - Lip, Gregory Y.H.
Y1  - 2015/11//
N1  - Accession Number: 110474428. Language: English. Entry Date: 20160311. Revision Date: 20160123. Publication Type: journal article. Journal Subset: Biomedical; USA. NLM UID: 101200317. 
SP  - 2332
EP  - 2343
JO  - Heart Rhythm
JF  - Heart Rhythm
JA  - HEART RHYTHM
VL  - 12
IS  - 11
CY  - New York, New York
PB  - Elsevier Science
AB  - The prevalence of atrial fibrillation (AF) and AF-related stroke is set to increase dramatically in coming decades, with developing regions such as Latin America experiencing the greatest impact. These trends are primarily driven by aging populations and by the increasing prevalence of the metabolic syndrome. The metabolic syndrome describes an association between diabetes, hypertension, obesity, and dyslipidemia and an increased risk of cardiovascular disease. It is in large part the result of unbalanced diet and sedentary lifestyle. These essentially modifiable risk factors are becoming more prevalent with the widespread adoption of so-called Western lifestyles. This review examines the physiology underlying the link between the metabolic syndrome and AF. Next, it highlights the importance of addressing lifestyle-related risk factors to mitigate the trend toward increasing AF prevalence. It then goes on to discuss the importance of stroke prevention therapy in patients with established AF, focusing on the relative merits of various available options for anticoagulation. Given the recent availability of comprehensive data on the 4 currently available non-vitamin K antagonist oral anticoagulant drugs, this review concludes by discussing the relative merits of specific agents in individual patient groups.
SN  - 1547-5271
AD  - British Heart Foundation Centre of Cardiovascular Excellence, St. Thomas’ Hospital, London, United Kingdom
AD  - Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom
AD  - University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, United Kingdom,
AD  - Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Faculty of Health, Aalborg University, Aalborg, Denmark
U2  - PMID: 26142297.
DO  - 10.1016/j.hrthm.2015.06.038
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 106029245
T1  - Migraine epidemiology, clinical presentations, and comorbidity.
Y1  - 2004/07//
N1  - Accession Number: 106029245. Language: English. Entry Date: 20081219. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 2985091R. 
SP  - 734
EP  - 735
JO  - Headache: The Journal of Head & Face Pain
JF  - Headache: The Journal of Head & Face Pain
JA  - HEADACHE
VL  - 44
IS  - 7
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Horton SC, Bunch TJ. Patent foramen ovale and stroke. Mayo Clin Proc. 2004;79:79-88. A patent foramen ovale (PFO) is a frequent remnant of embryological development with clinical importance in thromboembolism, paradoxical embolism, stroke, platypnea-orthodeoxia, decompression sickness, and migraine headache. The proposed mechanisms of stroke with PFO include paradoxical embolization, in situ thrombosis within the canal of the PFO, associated atrial arrhythmias, and concomitant hypercoagulable states. Prospective trials using aspirin treatment to reduce recurrent stroke showed a significant recurrence of neurologic events in patients with a PFO and atrial septal aneurysm. Use of warfarin anticoagulation does not further reduce recurrent stroke rates compared with antiplatelet therapy. Both surgical and catheter-based modes of closure have been shown to decrease the rate of subsequent embolic events substantially. Successful closure, defined by transesophageal echocardiography, appears to predict freedom from subsequent embolic events. To our knowledge, no randomized trials comparing anticoagulation with surgical or catheter-based closure have been performed. Adams HP Jr. Patent foramen ovale: paradoxical embolism and paradoxical data. Mayo Clin Proc. 2004;79:15-20. Some cardiologists estimate that 60,000 to 110,000 strokes are secondary to paradoxical embolism via a PFO. Besides preventing stroke, transcatheter closure of PFO has been proposed as a prophylactic treatment for migraine headache. However, questions persist. Much of the current evidence is circumstantial or anecdotal. Reports about the potential utility of medical or surgical interventions are from uncontrolled studies, which can be biased. When the rules of evidence are used, these studies provide data of modest strength. Of note, evidence from prospective clinical studies has not matched our preconceived notions. Specifically the risk of stroke might not be as high as previously believed, and relatively conservative medical therapies might be effective. Because of reservations about the robustness of the current data, many neurologists are uncertain about the cause-and-effect relationship between PFO and stroke and about the best management of patients. Comments: The relationship of PFO and atrial septal aneurysm (ASA) to migraine with aura (MA) is being increasingly recognized. The issue, as Dr. Adams describes, is an appropriate treatment. Dr. John Edmeads, former editor of this journal, speculated recently that PFO could generate MA by showering neuroinflammatory or vasodilating peptides downstream, triggering cortical spreading depression, but he noted that this was pure speculation. Complicating the picture is the risk for stroke with PFO, and the reported beneficial effect of aspirin in the prophylaxis of migraine (Buring JE, Peto R, Hennekens CH. Low-dose aspirin for migraine prophylaxis. JAMA. 1990;264:1711-1713). Some clinicians report that the aspirin effect is more likely to be seen in MA. Is the aspirin showing its benefit due to its effect on the undiagnosed and symptomatic PFO subset of MA patients? Stewart J. Tepper Once again the concepts of PFO and ASA are raised as possible vascular causes for MA. Might this also explain the paucity of effect for either SC sumatriptan or any of the oral triptans in treating MA during the aura, since the underlying pathophysiology may be different? This important paper also emphasizes the need for a multidisciplinary approach to headache treatment to ensure that the neurologist or headache doctor doesn't forget to use his stethoscope! David S. Millson Ohayon MM. Prevalence and risk factors of morning headaches in the general population. Arch Intern Med. 2004;164:97-102. Objective: To determine the prevalence of chronic morning headaches (CMH) in the general population and their relationship to sociodemographic characteristics, psychoactive substance use, and organic, sleep, and mental disorders. Methods: A telephone questionnaire was submitted to 18,980 individuals aged 15 years or older, which was representative of the general populations of the United Kingdom, Germany, Italy, Portugal, and Spain. It included a series of questions about morning headaches, organic disorders, use of psychoactive substances, and sleep and mental disorders in accordance with the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). Results: Overall, the prevalence of CMH was 7.6% (n = 1442); CMH were reported to occur 'daily' by 1.3% of the sample, 'often' by 4.4%, and 'sometimes' by 1.9%. Rates were higher in women than in men (8.4% vs. 6.7%) and in subjects aged between 45 and 64 years (about 9%). The median duration for CMH was 42 months. Various conditions and disorders were found positively associated with CMH. The most significant associated factors were comorbid anxiety and depressive disorders (28.5% vs. 5.5%), major depressive disorder alone (21.3% vs. 5.5%), dyssomnia not otherwise specified (17.1% vs. 6.9%), insomnia disorder (14.4% vs. 6.9%), and circadian rhythm disorder (20.0% vs. 7.5%). Sleep-related breathing disorder (15.2% vs. 7.5%), hypertension (11.0% vs. 7.2%), musculoskeletal diseases (14.1% vs. 7.1%), use of anxiolytic medication (20.1% vs. 7.3%), and heavy alcohol consumption (12.6% vs. 7.7%) were also significantly associated with CMH. Conclusions: Morning headache affects 1 in 13 individuals in the general population. Chronic morning headaches are a good indicator of major depressive disorders and insomnia disorders. Contrary to what was previously suggested, however, they are not specific to sleep-related breathing disorder. Comments: I have personally encountered young headache patients with episodic morning headaches who have 'abused' illicit psychoactive drugs such as cannabis. The prevalence of cannabis use in the Netherlands is reported to be as high as 10% in young adults since its deregulation { }. Recent downgrading of cannabis criminal classification in the United Kingdom (decriminalization) might be expected to have a similar effect. It might be interesting to repeat this study and ask specifically about illicit drug use. David S. Millson This study is hard to sort out. I suspect the episodic morning headaches were migraine, which occur frequently in the morning (Fox AW, Davis RL. Migraine Chronobiology. Headache. 1998;38:436-441). However, as Dr. Ninan Mathew has been pointing out for over a decade, chronic daily headaches with morning presentation and circadian rhythmicity are likely to be associated with medication overuse, with withdrawal during the night presenting with headache in the morning. And rebound is highly associated with comorbid depression and anxiety. So my suspicion is that a large number of the patients described in this study were, in fact, medication-overuse headache patients with underlying episodic migraine, and it is therefore not surprising that these patients did not have a related sleep disorder. Stewart J. Tepper von Brevern M, Radtke A, Clarke AH, Lempert T. Migrainous vertigo presenting as episodic positional vertigo. Neurology. 2004;62:469-472. Migraine can cause vestibular symptoms including positional vertigo. Of 362 consecutive patients presenting with positional vertigo, 10 with migrainous vertigo mimicking benign paroxysmal positional vertigo (BPPV) were identified. The following factors help to distinguish migrainous positional vertigo from BPPV: short-duration symptomatic episodes and frequent recurrences, manifestation early in life, migrainous symptoms during episodes with positional vertigo, and atypical positional nystagmus. Neuhauser H, Lempert T. Vertigo and dizziness related to migraine: a diagnostic challenge. Cephalalgia. 2004;24:83-91. Vertigo and dizziness can be related to migraine in various ways: causally, statistically, or quite frequently, just by chance. Migrainous vertigo (MV) is a vestibular syndrome caused by migraine and presents with attacks of spontaneous or positional vertigo lasting seconds to days and migrainous symptoms during the attack. MV is the most common cause of spontaneous recurrent vertigo and is presently not included in the International Headache Society classification of migraine. Benign paroxysmal positional vertigo (BPPV) and Ménière's disease (MD) are statistically related to migraine, but the possible pathogenetic links have not been established. Moreover, migraineurs get motion sickness more often than controls. Persistent cerebellar symptoms may develop in the course of familial hemiplegic migraine. Dizziness may also be due to orthostatic hypotension, anxiety disorders, or major depression and all have an increased prevalence in patients with migraine. Brandt T. A chameleon among the episodic vertigo syndromes: 'migrainous vertigo' or 'vestibular migraine'. Cephalalgia. 2004;24:81-82, which concludes: Neuhauser and Lempert rightly draw our attention to the fact that whether called 'migrainous vertigo' or 'vestibular migraine,' this entity is missing form the extensive official classification of the IHS despite its frequency and clinical relevance. Comments: Both the von Brevern et al article and the Neuhauser and Lempert article make similar points: vertigo and migraine are commonly associated, and pathophysiologically related. I believe that the temporal relationship clinically helps to make the diagnosis. Dr. Robert Baloh of UCLA (University of California, Los Angeles) used to say that the treatment of migrainous vertigo is the treatment of migraine. Dr. Morris Levin of Dartmouth wrote an excellent chapter on the subject in a case study book (Levin M. The Patient with Headache and Dizziness. In: Tepper, SJ, Sheftell FD, Rapoport AM, eds. The Spectrum of Migraine. NY: MacMahon Publishing Group, 2002) and cited work by Dr. Glenn Johnson, also at Dartmouth, in recommending use of 'all typical migraine prophylactic agents and selective serotonin reuptake inhibitor medications such as sertraline 'plus' the importance of nonpharmacologic treatments such as dietary changes, physical therapy, and lifestyle adaptation.' As headache clinicians, we need to validate the clinical characteristics of migrainous vertigo for its inclusion in the revised IHS system of the future. Stewart J. Tepper Distinguishing vestibular migraine from basilar-type migraine is important, since triptans are currently contraindicated in baslar-type migraine, based largely on a speculative hypothesis that they might compromise vertebrobasilar blood flow, leading to infarction. There is little clinical evidence that I am aware of to substantiate this concern, and the validation of an IHS classification distinction proposed by Dr. Tepper might well help to clarify issues here. David S. Millson
SN  - 0017-8748
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 59196308
T1  - MNRS News...Midwest Nursing Research Society (MNRS)
AU  - Rawl, Susan M.
AU  - Lusk, Sally L.
Y1  - 2011/04//
N1  - Accession Number: 59196308. Language: English. Entry Date: 20110406. Revision Date: 20110406. Publication Type: Article. Journal Subset: Core Nursing; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 7905435. 
KW  - Research, Nursing
KW  - Research Support
KW  - Theses and Dissertations
KW  - Shared Governance
KW  - Cancer Fatigue
KW  - Breast Neoplasms -- Diagnosis
KW  - Insulin Resistance
KW  - Yoga
KW  - Osteoarthritis -- Therapy
KW  - Wireless Communications
KW  - Treatment Delay
KW  - Atrial Fibrillation -- Therapy
KW  - Research, Nursing -- Organizations
SP  - 472
EP  - 479
JO  - Western Journal of Nursing Research
JF  - Western Journal of Nursing Research
JA  - WEST J NURS RES
VL  - 33
IS  - 3
CY  - Thousand Oaks, California
PB  - Sage Publications Inc.
SN  - 0193-9459
AD  - MNRS Board of Directors
AD  - MNRS Foundation
DO  - 10.1177/0193945911400697
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104839268
T1  - MNRS News...Midwest Nursing Research Society (MNRS)
AU  - Rawl, Susan M.
AU  - Lusk, Sally L.
Y1  - 2011/04//
N1  - Accession Number: 104839268. Language: English. Entry Date: 20110406. Revision Date: 20150711. Publication Type: Journal Article; abstract; research. Journal Subset: Core Nursing; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 7905435. 
KW  - Research, Nursing
KW  - Research Support
KW  - Theses and Dissertations
KW  - Shared Governance
KW  - Cancer Fatigue
KW  - Breast Neoplasms -- Diagnosis
KW  - Insulin Resistance
KW  - Yoga
KW  - Osteoarthritis -- Therapy
KW  - Wireless Communications
KW  - Treatment Delay
KW  - Atrial Fibrillation -- Therapy
KW  - Research, Nursing -- Organizations
SP  - 472
EP  - 479
JO  - Western Journal of Nursing Research
JF  - Western Journal of Nursing Research
JA  - WEST J NURS RES
VL  - 33
IS  - 3
CY  - Thousand Oaks, California
PB  - Sage Publications Inc.
SN  - 0193-9459
AD  - MNRS Board of Directors
AD  - MNRS Foundation
U2  - PMID: 21386038.
DO  - 10.1177/0193945911400697
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 110815821
T1  - Moderate exercise lowers risk of atrial fibrillation in older women.
AU  - SAVILL, PETER
Y1  - 2015/10//
N1  - Accession Number: 110815821. Language: English. Entry Date: 20160220. Revision Date: 20151111. Publication Type: Article. Journal Subset: Biomedical; Europe; UK & Ireland. NLM UID: 0404245. 
SP  - 8
EP  - 10
JO  - Practitioner
JF  - Practitioner
JA  - PRACTITIONER
VL  - 259
IS  - 1786
PB  - Practitioner Medical Publishing Ltd.
SN  - 0032-6518
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ER  - 

TY  - JOUR
ID  - 108099533
T1  - Music and paroxysmal atrial fibrillation.
AU  - Challans, Shelly A
AU  - Kocheril, Abraham G
AU  - Prasun, Marilyn
Y1  - 2012/08//2012 Aug
N1  - Accession Number: 108099533. Language: English. Entry Date: 20121109. Revision Date: 20150712. Publication Type: Journal Article. Journal Subset: Allied Health; Biomedical; USA. Special Interest: Laboratory Diagnosis. NLM UID: 101174623. 
KW  - Atrial Fibrillation -- Therapy
KW  - Music Therapy
KW  - Clinical Research
SP  - 4p
EP  - 4p
JO  - EP Lab Digest
JF  - EP Lab Digest
JA  - EP LAB DIGEST
VL  - 12
IS  - 8
CY  - Malvern, Pennsylvania
PB  - HMP Communications
SN  - 1535-2226
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108099533&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106631919
T1  - n-3 Fatty acids consumed from fish and risk of atrial fibrillation or flutter: the Danish Diet, Cancer, and Health Study.
AU  - Frost L
AU  - Vestergaard P
Y1  - 2005/01//
N1  - Accession Number: 106631919. Language: English. Entry Date: 20050513. Revision Date: 20150819. Publication Type: Journal Article; research; tables/charts. Journal Subset: Allied Health; Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Grant Information: Supported by the Danish Medical Research Council (grant 22-02-0582). NLM UID: 0376027. 
KW  - Fatty Acids, Omega-3
KW  - Fish
KW  - Diet
KW  - Atrial Fibrillation
KW  - Atrial Flutter
KW  - Prospective Studies
KW  - Denmark
KW  - Diet, Antineoplastic
KW  - Nutritional Assessment
KW  - Cox Proportional Hazards Model
KW  - Male
KW  - Female
KW  - Odds Ratio
KW  - Body Weights and Measures
KW  - Questionnaires
KW  - Data Analysis Software
KW  - Validity
KW  - Record Review
KW  - Linear Regression
KW  - Body Mass Index -- Evaluation
KW  - Health Behavior -- Evaluation
KW  - Health Status -- Evaluation
KW  - Spearman's Rank Correlation Coefficient
KW  - Confidence Intervals
KW  - Middle Age
KW  - Descriptive Statistics
KW  - Funding Source
KW  - Human
SP  - 50
EP  - 54
JO  - American Journal of Clinical Nutrition
JF  - American Journal of Clinical Nutrition
JA  - AM J CLIN NUTR
VL  - 81
IS  - 1
CY  - Bethesda, Maryland
PB  - American Society for Nutrition
AB  - BACKGROUND: Experimental studies have shown that n-3 polyunsaturated fatty acids in fish may have antiarrhythmic properties. OBJECTIVE: We examined the association between consumption of n-3 fatty acids from fish and risk of atrial fibrillation or flutter. DESIGN: In a prospective cohort study of 47 949 participants (mean age: 56 y) in the Danish Diet, Cancer, and Health Study, we investigated the relation between the consumption of n-3 fatty acids from fish estimated from a detailed semiquantitative food questionnaire and risk of atrial fibrillation or flutter. The subjects were followed up in the Danish National Registry of Patients for the occurrence of atrial fibrillation or flutter and in the Danish Civil Registration System (vital status and emigration). The consumption of n-3 fatty acids from fish was analyzed as sex-specific quintiles with the use of Cox proportional hazards models. RESULTS: During follow-up (x: 5.7 y), atrial fibrillation or flutter had developed in 556 subjects (374 men and 182 women). When the lowest quintile of n-3 fatty acids consumed from fish was used as a reference, the unadjusted hazard rate ratios in quintiles 2, 3, 4, and 5 were 0.93, 1.11, 1.10, and 1.44, respectively (P for trend = 0.001). The corresponding adjusted hazard rate ratios were 0.86, 1.08, 1.01, and 1.34 (P for trend = 0.006). Inclusion of information on the frequency of fatty fish consumption did not alter these associations. CONCLUSIONS: Consumption of n-3 fatty acids from fish was not associated with a reduction in risk of atrial fibrillation or flutter. We cannot exclude the possibility of residual confounding caused by a lack of information on intake of fish-oil tablets. Copyright © 2005 American Society for Clinical Nutrition
SN  - 0002-9165
AD  - Department of Cardiology, Aarhus University Hospital, Aarhus Amtssygehus, DK8000 Aarhus C, Denmark; rlg041fr@as.aaa.dk
U2  - PMID: 15640459.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106631919&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104980196
T1  - New drug offers warfarin alternative for atrial fibrillation: an immediate switch is right for some people, but not necessary for all.
Y1  - 2011/02//
N1  - Accession Number: 104980196. Language: English. Entry Date: 20110209. Revision Date: 20150711. Publication Type: Journal Article; pictorial. Journal Subset: Biomedical; USA. NLM UID: 9425723. 
KW  - Anticoagulants
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Stroke -- Prevention and Control
KW  - Warfarin -- Therapeutic Use
KW  - Hemorrhage -- Prevention and Control
KW  - Drug Approval
KW  - Diet
KW  - Anticoagulants -- Economics
KW  - Anticoagulants -- Administration and Dosage
KW  - Anticoagulants -- Adverse Effects
SP  - 5
EP  - 5
JO  - Harvard Heart Letter
JF  - Harvard Heart Letter
JA  - HARV HEART LETT
VL  - 21
IS  - 6
CY  - Stamford, Connecticut
PB  - Harvard Health Publications
SN  - 1051-5313
U2  - PMID: 21449127.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104980196&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104417972
T1  - New Options for Stroke Prevention in Atrial Fibrillation.
AU  - Cannon, Christopher P.
AU  - Stecker, Eric C.
Y1  - 2010/11/02/Nov2010 Supplement
N1  - Accession Number: 104417972. Language: English. Entry Date: 20120921. Revision Date: 20150711. Publication Type: Journal Article; CEU; tables/charts. Supplement Title: Nov2010 Supplement. Journal Subset: Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Health Services Administration; Peer Reviewed; USA. Grant Information: Financial support for this work was provided by an educational grant from Boehringer Ingelheim Corporation.. NLM UID: 9613960. 
KW  - Atrial Fibrillation -- Complications
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Stroke -- Prevention and Control
KW  - Funding Source
KW  - Education, Continuing (Credit)
KW  - Fibrinolytic Agents -- Therapeutic Use
KW  - Fibrinolytic Agents -- Administration and Dosage
KW  - Fibrinolytic Agents -- Adverse Effects
KW  - Warfarin -- Therapeutic Use
SP  - S291
EP  - 7
JO  - American Journal of Managed Care
JF  - American Journal of Managed Care
JA  - AM J MANAGE CARE
VL  - 16
CY  - Plainsboro, New Jersey
PB  - Intellisphere, LLC
AB  - Randomized trials have demonstrated that warfarin is effective for stroke prevention in patients with atrial fibrillation (AF), yielding relative risk reductions for ischemic stroke of nearly 70%. However, successful use of warfarin requires frequent monitoring and dose adjustment to maintain an international normalized ratio (INR) within the range of 2.0 to 3.0. Many clinicians and patients have been reluctant to use warfarin therapy in AF, with underuse generally attributed to the inconvenience of INR monitoring, complexities of drug and dietary interactions associated with warfarin, and perceived bleeding risk. The ensuing search for safe, effective alternatives with a lower associated risk of bleeding and no need for monitoring and dose adjustment has focused attention on more specific inhibitors of the clotting cascade, such as factor Xa inhibitors or direct thrombin inhibitors. The direct thrombin inhibitor dabigatran has recently been approved by the US Food and Drug Administration for the prevention of stroke in patients with AF. New factor Xa inhibitors apixaban, rivaroxaban, and edoxaban are also currently being studied in stroke prevention trials in patients with AF to determine their comparability with warfarin. It is anticipated that fixed-dose administration of these new oral agents will provide effective anticoagulation without the need for frequent monitoring and with a lower risk of bleeding events.
SN  - 1088-0224
AD  - Harvard Medical School, Harvard University, Division of Cardiology and Brigham and Women's Hospital, Boston, MA
AD  - Oregon Health & Science University, Portland, OR
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104417972&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103906457
T1  - News Briefs.
Y1  - 2014/10//
N1  - Accession Number: 103906457. Language: English. Entry Date: 20141028. Revision Date: 20151001. Publication Type: Journal Article. Journal Subset: Alternative/Complementary Therapies; Biomedical; Peer Reviewed; USA. NLM UID: 9500579. 
KW  - Electroacupuncture
KW  - Aromatase Inhibitors -- Adverse Effects
KW  - Fatigue -- Therapy
KW  - Sleep Disorders -- Therapy
KW  - Stress, Psychological -- Therapy
KW  - Breast Neoplasms -- Drug Therapy
KW  - Postmenopause
KW  - Breast Neoplasms -- Prevention and Control
KW  - Blacks
KW  - Atrial Fibrillation -- Risk Factors
KW  - Obesity -- Complications
KW  - Physical Activity
KW  - Vitamin D Deficiency -- Complications
KW  - Dementia -- Risk Factors
KW  - Diabetes Mellitus, Type 2 -- Diet Therapy
KW  - Nuts -- Therapeutic Use
KW  - Glycemic Control
KW  - Cardiovascular Risk Factors -- Prevention and Control
KW  - Sitting
KW  - Blood Pressure -- Drug Effects
KW  - Potassium -- Therapeutic Use
KW  - Sodium, Dietary -- Adverse Effects
KW  - Lipoproteins, HDL Cholesterol -- Blood
KW  - Vitamin D -- Blood
KW  - Fertility
KW  - Tai Chi -- In Old Age
KW  - Female
KW  - Pregnancy
KW  - Labor Pain -- Prevention and Control
KW  - Aged
KW  - Tonsillitis -- Drug Therapy -- In Infancy and Childhood
KW  - Homeopathic Agents -- Therapeutic Use -- In Infancy and Childhood
KW  - Child
KW  - Probiotics
SP  - 225
EP  - 229
JO  - Alternative & Complementary Therapies
JF  - Alternative & Complementary Therapies
JA  - ALTERN COMPLEMENT THER
VL  - 20
IS  - 5
CY  - New Rochelle, New York
PB  - Mary Ann Liebert, Inc.
SN  - 1076-2809
DO  - 10.1089/act.2014.20508
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103906457&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104893782
T1  - News You Can Use.
Y1  - 2011/04//
N1  - Accession Number: 104893782. Language: English. Entry Date: 20110610. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Alternative/Complementary Therapies; Biomedical; Peer Reviewed; USA. NLM UID: 9500579. 
KW  - Alternative Therapies
KW  - Hepatic Encephalopathy -- Drug Therapy
KW  - Carnitine -- Therapeutic Use
KW  - Folic Acid -- Therapeutic Use
KW  - Colorectal Neoplasms -- Prevention and Control
KW  - Yoga
KW  - Atrial Fibrillation -- Therapy
KW  - Glycemic Control
KW  - Vitamin D -- Therapeutic Use
KW  - Diabetic Patients
KW  - Migraine -- Therapy
KW  - Manipulation, Osteopathic
KW  - Placebo Effect
KW  - Pain -- Drug Therapy
KW  - Morphine -- Therapeutic Use
KW  - Consumer Health Information
KW  - National Center for Complementary and Alternative Medicine (U.S.)
SP  - 63
EP  - 65
JO  - Alternative & Complementary Therapies
JF  - Alternative & Complementary Therapies
JA  - ALTERN COMPLEMENT THER
VL  - 17
IS  - 2
CY  - New Rochelle, New York
PB  - Mary Ann Liebert, Inc.
SN  - 1076-2809
DO  - 10.1089/act.2011.17211
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104893782&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107827711
T1  - News.
Y1  - 2014/07//Jul-Sep2014
N1  - Accession Number: 107827711. Language: English. Entry Date: 20140923. Revision Date: 20150712. Publication Type: Journal Article. Journal Subset: Biomedical; Blind Peer Reviewed; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9503762. 
KW  - Practice Guidelines
KW  - Government Agencies
KW  - Cardiology
KW  - News
KW  - United Kingdom
KW  - Atrial Fibrillation -- Therapy
KW  - Atrial Fibrillation -- Complications
KW  - Stroke -- Prevention and Control
KW  - Lipids -- Analysis
KW  - Hyperlipidemia -- Therapy
KW  - Statins -- Administration and Dosage
KW  - Weight Control
KW  - Life Style Changes
KW  - Acute Coronary Syndrome -- Therapy
SP  - 98
EP  - 98
JO  - British Journal of Cardiology
JF  - British Journal of Cardiology
JA  - BR J CARDIOL
VL  - 21
IS  - 3
PB  - MediNews (Cardiology) Ltd.
SN  - 0969-6113
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107827711&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108138393
T1  - News.
AU  - Sherman, Lisa
Y1  - 2012/06//
N1  - Accession Number: 108138393. Language: English. Entry Date: 20120831. Revision Date: 20150712. Publication Type: Journal Article; abstract. Journal Subset: Alternative/Complementary Therapies; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. NLM UID: 8101969. 
KW  - Medicine, Chinese Traditional
KW  - Serial Publications
KW  - Abnormalities -- Risk Factors
KW  - Abortion, Spontaneous -- Prevention and Control
KW  - Acupuncture
KW  - Acupuncture -- Adverse Effects
KW  - Aged
KW  - Aggression -- Risk Factors
KW  - Antimalarials -- Adverse Effects
KW  - Anxiety -- Therapy
KW  - Atrial Fibrillation -- Therapy
KW  - Back Pain -- Therapy
KW  - Bacteria
KW  - Brain Injuries -- Therapy
KW  - Breast Neoplasms -- Complications
KW  - Carpal Tunnel Syndrome -- Therapy
KW  - Depression -- Therapy
KW  - Diabetes Mellitus -- Risk Factors
KW  - Disabled
KW  - Drug Resistance
KW  - Drug Resistance, Microbial
KW  - Dyspepsia -- Therapy
KW  - Electric Stimulation
KW  - Electroacupuncture
KW  - Exercise
KW  - Fertilization in Vitro -- Adverse Effects
KW  - Fertilization in Vitro -- Methods
KW  - Food Habits
KW  - Gastrointestinal System
KW  - Green Tea
KW  - Health Services
KW  - Heart Rate
KW  - Hypersensitivity -- Complications
KW  - Inflammatory Bowel Diseases -- Therapy
KW  - Irritable Bowel Syndrome -- Therapy
KW  - Labor Pain -- Therapy
KW  - Malaria -- Complications
KW  - Medicine, Herbal
KW  - Memory
KW  - Menorrhagia -- Therapy
KW  - Migraine -- Therapy
KW  - Muscle Strengthening
KW  - Neoplasms -- Complications
KW  - Obesity -- Risk Factors
KW  - Parkinson Disease -- Therapy
KW  - Pelvic Pain -- Therapy
KW  - Polycystic Ovary Syndrome -- Therapy
KW  - Postoperative Pain -- Therapy
KW  - Professional-Patient Relations
KW  - Pruritus -- Therapy
KW  - Rhinitis -- Therapy
KW  - Rice
KW  - Self Care
KW  - Sinusitis -- Therapy
KW  - Sleep Deprivation -- Complications
KW  - Stroke -- Therapy
KW  - Tai Chi
KW  - Trans Fatty Acids -- Adverse Effects
KW  - United Kingdom
KW  - Weight Loss
SP  - 68
EP  - 76
JO  - Journal of Chinese Medicine
JF  - Journal of Chinese Medicine
JA  - J CHINESE MED
IS  - 99
PB  - Journal of Chinese Medicine
SN  - 0143-8042
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108138393&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107944909
T1  - newsbites.
Y1  - 2013/06//2013 Jun
N1  - Accession Number: 107944909. Language: English. Entry Date: 20130712. Revision Date: 20150712. Publication Type: Journal Article. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Evidence-Based Practice; Nutrition. NLM UID: 101322645. 
KW  - Atrial Fibrillation
KW  - Cardiovascular Risk Factors
KW  - Diet -- Evaluation
KW  - Fish Oils -- Administration and Dosage
KW  - Neoplasms -- Risk Factors
KW  - Smoking Cessation
KW  - Weight Gain -- Evaluation
SP  - 12
EP  - 12
JO  - Clinical Nutrition Insight
JF  - Clinical Nutrition Insight
JA  - CLIN NUTR INSIGHT
VL  - 39
IS  - 6
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
SN  - 1938-8640
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107944909&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109473430
T1  - NICE Guideline 14.
Y1  - 2015/08//
N1  - Accession Number: 109473430. Language: English. Entry Date: 20150924. Revision Date: 20150924. Publication Type: Article. Journal Subset: Biomedical; Editorial Board Reviewed; Europe; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice. 
KW  - Melanoma -- Diagnosis
KW  - Melanoma -- Therapy
KW  - Smoking Cessation
KW  - Counseling
KW  - Atrial Fibrillation -- Therapy
KW  - Pediatric Obesity -- Prevention and Control
KW  - Weight Control
KW  - Life Style Changes
SP  - 37
EP  - 37
JO  - Guidelines in Practice
JF  - Guidelines in Practice
JA  - GUIDELINES PRACT
VL  - 18
IS  - 8
PB  - Medendium Group Publishing Ltd.
SN  - 1464-6420
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109473430&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 116087486
T1  - NOAC monitoring, reversal agents, and post-approval safety and effectiveness evaluation: A cardiac safety research consortium think tank.
AU  - Reiffel, James A.
AU  - Weitz, Jeffrey I.
AU  - Reilly, Paul
AU  - Kaminskas, Edvardas
AU  - Sarich, Troy
AU  - Sager, Philip
AU  - Seltzer, Jonathan
Y1  - 2016/07//
N1  - Accession Number: 116087486. Corporate Author: Cardiac Safety Research Consortium presenters and participants. Language: English. Entry Date: In Process. Revision Date: 20160616. Publication Type: journal article. Journal Subset: Biomedical; USA. NLM UID: 0370465. 
SP  - 74
EP  - 86
JO  - American Heart Journal
JF  - American Heart Journal
JA  - AM HEART J
VL  - 177
CY  - New York, New York
PB  - Elsevier Science
AB  - Four non-vitamin K antagonist oral anticoagulants (dabigatran, rivaroxaban, apixaban, and edoxaban) have been approved in the United States for treatment of atrial fibrillation (AF) and venous thromboembolic disease. They have been as or more effective than the prior standards of care, with less fatal or intracranial bleeding, fewer drug and dietary interactions, and greater patient convenience. Nonetheless, the absence of the ability for clinicians to assess compliance or washout with a simple laboratory test (or to adjust dosing with a similar assessment) and the absence of an antidote to rapidly stop major hemorrhage or to enhance safety in the setting of emergent or urgent surgery/procedures have been limitations to greater non-vitamin K antagonist oral anticoagulant usage and better thromboembolic prevention. Accordingly, a Cardiac Research Safety Consortium "think tank" meeting was held in February 2015 to address these concerns. This manuscript reports on the discussions held and the conclusions reached at that meeting.
SN  - 0002-8703
AD  - Columbia University, New York, NY
AD  - McMaster University and Thrombosis and Atherosclerosis Research Institute, Ontario, Canada
AD  - Employee of Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT
AD  - Division of Hematology Products, CDER, FDA, Silver Springs, MD
AD  - Employee of Janssen Scientific Affairs, LLC, Titusville, NJ
AD  - Stanford University and Sager Consulting Experts, San Francisco, CA
AD  - Employee of ACI Clinical and Lankenau Heart Institute, Wynnewood, PA
U2  - PMID: 27297852.
DO  - 10.1016/j.ahj.2016.04.010
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=116087486&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104539666
T1  - Non-adherence to warfarin: a case study.
AU  - Duke, Natasha
Y1  - 2012/02//
N1  - Accession Number: 104539666. Language: English. Entry Date: 20120420. Revision Date: 20150818. Publication Type: Journal Article; case study; tables/charts. Journal Subset: Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 101175794. 
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Medication Compliance
KW  - Warfarin -- Therapeutic Use
KW  - Aged, 80 and Over
KW  - Alzheimer's Disease
KW  - Atrial Fibrillation -- Diagnosis
KW  - Atrial Fibrillation -- Etiology
KW  - Atrial Fibrillation -- Physiopathology
KW  - Checklists
KW  - Drug Monitoring
KW  - Female
KW  - Information Resources
KW  - International Normalized Ratio
KW  - Office Nursing
KW  - Patient Assessment
KW  - Patient Care Plans
KW  - World Wide Web
SP  - 72
EP  - 79
JO  - Nurse Prescribing
JF  - Nurse Prescribing
JA  - NURSE PRESCRIBING
VL  - 10
IS  - 2
PB  - MA Healthcare Limited
AB  - Atrial fibrillation (AF) is a major risk factor for stroke, requiring monitoring and treatment. If there are no significant risk factors, warfarin therapy may be prescribed for some types of AF, but necessitates compliance, careful monitoring and dose adjustment. Many factors influence the effectiveness of warfarin therapy, including alcohol consumption, dietary constituents, herbal supplements, and prescribed or over-the-counter medicines. Compliance, in turn, can be affected by factors such as the presence of dementia or cognitive impairment. As exemplified in this case study, a structured approach for the management of warfarin should be adopted, ensuring factors affecting compliance or drug effectiveness may be identified and appropriate action can be taken.
SN  - 1479-9189
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104539666&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106038955
T1  - Noninvasive arrhythmia risk stratification in idiopathic dilated cardiomyopathy: design and first results of the marburg cardiomyopathy study.
AU  - Grimm W
AU  - Glaveris C
AU  - Hoffmann J
AU  - Menz V
AU  - Mey N
AU  - Born S
AU  - Maisch B
Y1  - 1998/11/15/
N1  - Accession Number: 106038955. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Allied Health; Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7803944. 
SP  - 2551
EP  - 2556
JO  - Pacing & Clinical Electrophysiology
JF  - Pacing & Clinical Electrophysiology
JA  - PACING CLIN ELECTROPHYSIOL
VL  - 21
IS  - 11P2
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - The Marburg Cardiomyopathy Study (MACAS) is a prospective, observational study designed to determine the value of the following potential noninvasive arrhythmia risk predictors in at least 200 patients with idiopathic dilated cardiomyopathy (IDC) over a 5-year follow-up period: NYHA-class, left ventricular ejection fraction (LVEF), left ventricular end-diastolic diameter, left bundle branch block and atrial fibrillation on ECG, QT/JT dispersion on 12-lead EGG, signal-averaged ECG, ventricular arrhythmias and heart rate variability (HRV) on 24-hour Holler ECG, baroreflex sensitivity, and microvolt T wave alternans during exercise. This article describes the findings among the first 159 patients with IDCs enrolled in MACAS until May 1998 (40 women, 119 men; age: 49 ± 12 years; LVEF: 32 ± 10%). Twenty-nine patients (18%) had atrial fibrillation and 130 patients (82%) were in sinus rhythm. Patients with sinus rhythm were further stratified according to LVEF < 30% (n = 54) Versus LVEF >= 30% (n = 76). Compared to patients with LVEF >= 30%, patients with LVEF <30% more often had left bundle branch block (43% vs 25%, P < 0.05), nonsustained VT (44% vs 22%, p <0.05), decreased HRV (SDNN 95 ± 39 vs 128 ± 42 ms, P < 0.01), decreased baroreflex sensitivity (5.6 ± 4 vs 8.3 ± 6 ms/mmHg, P <0.01), and T wave alternans (59% vs 37%, P < 0.05). The prognostic significance of these findings will be determined by multivariate Cox analysis at the end of a 5-year follow-up. Primary end points in MACAS are overall mortality and arrhythmic events (i.e., sustained VT or VF, or sudden cardiac death).
SN  - 0147-8389
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105239125
T1  - Non-invasive assessment of left ventricular relaxation during atrial fibrillation using mitral flow propagation velocity.
AU  - Asada-Kamiguchi J
AU  - Tabata T
AU  - Popovic ZB
AU  - Greenberg NL
AU  - Kim YJ
AU  - Garcia MJ
AU  - Wallick DW
AU  - Mowrey KA
AU  - Zhuang S
AU  - Zhang Y
AU  - Mazgalev TN
AU  - Thomas JD
AU  - Grimm RA
Y1  - 2009/10//
N1  - Accession Number: 105239125. Language: English. Entry Date: 20100101. Revision Date: 20150711. Publication Type: Journal Article; diagnostic images; research; tables/charts; tracings. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. Grant Information: Supported in part by American Heart Association Grant AHA-9808489A and NIH Grant RO1-HL-60833-01A1, the National Space Biomedical Research Institute through NASA NCC 9-58 and the Department of Defense USAMRMC Grant No. 02360007. NLM UID: 100890618. 
KW  - Atrial Fibrillation -- Ultrasonography
KW  - Blood Flow Velocity -- Evaluation
KW  - Echocardiography, Doppler, Color -- Methods
KW  - Heart Ventricle, Left -- Physiopathology
KW  - Animal Studies
KW  - Descriptive Statistics
KW  - Dogs
KW  - Funding Source
KW  - Heart Ventricle, Left -- Ultrasonography
KW  - Mitral Valve -- Physiopathology
KW  - Mitral Valve -- Ultrasonography
KW  - Models, Biological
KW  - One-Way Analysis of Variance
KW  - Paired T-Tests
KW  - Regression
KW  - Repeated Measures
SP  - 826
EP  - 832
JO  - European Journal of Echocardiography
JF  - European Journal of Echocardiography
JA  - EUR J ECHOCARDIOGRAPHY
VL  - 10
IS  - 7
PB  - Oxford University Press / USA
SN  - 1525-2167
AD  - Section of Cardiovascular Imaging, Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
U2  - PMID: 19692424.
DO  - ejechocard/jep083
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105239125&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107964728
T1  - Novel oral anticoagulants: A review of new agents.
AU  - Wanat, Matthew A
Y1  - 2013/07//2013 Jul
N1  - Accession Number: 107964728. Language: English. Entry Date: 20131101. Revision Date: 20150712. Publication Type: Journal Article. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 0401147. 
KW  - Anticoagulants -- Therapeutic Use
KW  - Heterocyclic Compounds -- Therapeutic Use
KW  - Pyridines -- Therapeutic Use
KW  - Sulfur Compounds -- Therapeutic Use
KW  - Alanine
KW  - Atrial Fibrillation -- Complications
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Drug Administration Schedule
KW  - Postoperative Complications -- Prevention and Control
KW  - Practice Guidelines
KW  - Pulmonary Embolism -- Etiology
KW  - Pulmonary Embolism -- Prevention and Control
KW  - Stroke -- Etiology
KW  - Stroke -- Prevention and Control
KW  - Venous Thromboembolism -- Drug Therapy
KW  - Venous Thromboembolism -- Etiology
KW  - Venous Thromboembolism -- Prevention and Control
KW  - Venous Thrombosis -- Drug Therapy
KW  - Venous Thrombosis -- Etiology
KW  - Venous Thrombosis -- Prevention and Control
KW  - Alanine -- Therapeutic Use
SP  - 103
EP  - 114
JO  - Postgraduate Medicine
JF  - Postgraduate Medicine
JA  - POSTGRAD MED
VL  - 125
IS  - 4
CY  - Philadelphia, Pennsylvania
PB  - Taylor & Francis Ltd
AB  - Until recently, warfarin had been one of the only treatment options for long-term anticoagulation of patients with atrial fibrillation, venous thromboembolism, or other medical conditions that require chronic anticoagulation. A main concern when treating patients with anticoagulants is balancing the benefits of preventing a thromboembolic event with the risks of bleeding events. The US Food and Drug Administration recently approved 2 new oral anticoagulants, dabigatran and rivaroxaban, for stroke prevention in patients with atrial fibrillation, and is currently reviewing a drug application for a third new oral anticoagulant, apixaban. These new anticoagulants do not require strict and frequent laboratory monitoring, dosing adjustments, or dietary restrictions, and they incur fewer drug-drug interactions than warfarin. However, these new medications do not have specific reversal agents, may require dosage adjustment based on patient renal function, and lack clinical data regarding their long-term safety and efficacy. The 2012 American College of Chest Physicians Evidence-Based Clinical Practice Guidelines for antithrombotic therapy and prevention of thrombosis include recommendations for dabigatran, rivaroxaban, and apixaban for certain indications. Each of the 3 novel oral anticoagulants has specific pharmacokinetic and pharmacodynamic properties that may make them suitable agents for use in specific patient populations. Knowledge of dosing, drug-drug interactions, monitoring parameters, and clinical considerations for each of these new medications will help clinicians decide for which patients they may be best suited to replace conventional therapy with warfarin.
SN  - 0032-5481
AD  - Department of Clinical Sciences and Administration, University of Houston College of Pharmacy, Houston, TX. mawanat@uh.edu.
U2  - PMID: 23933899.
DO  - 10.3810/pgm.2013.07.2683
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107964728&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104489057
T1  - Nut consumption and risk of atrial fibrillation in the Physicians' Health Study.
AU  - Khawaja, O
AU  - Gaziano, J M
AU  - Djousse, L
Y1  - 2012/01//
N1  - Accession Number: 104489057. Language: English. Entry Date: 20130802. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; UK & Ireland. Special Interest: Nutrition. Instrumentation: Food Frequency Questionnaire (FFQ). NLM UID: 101152213. 
KW  - Atrial Fibrillation -- Epidemiology
KW  - Health Status
KW  - Nuts
KW  - Physicians -- Statistics and Numerical Data
KW  - Adult
KW  - Aged
KW  - Aged, 80 and Over
KW  - Atrial Fibrillation -- Etiology
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Body Mass Index
KW  - Clinical Trials
KW  - Cox Proportional Hazards Model
KW  - Diet
KW  - Human
KW  - Incidence
KW  - Male
KW  - Middle Age
KW  - Multivariate Analysis
KW  - Odds Ratio
KW  - Prospective Studies
KW  - Questionnaires
KW  - Risk Factors
SP  - 17
EP  - 17
JO  - Nutrition Journal
JF  - Nutrition Journal
JA  - NUTR J
VL  - 11
IS  - 1
PB  - BioMed Central
SN  - 1475-2891
AD  - Harvard Medical School, Boston, MA, USA. oajaz@yahoo.com
U2  - PMID: 22436091.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104489057&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104805710
T1  - Omega-3 polyunsaturated fatty acids: food or medicine?
AU  - Ramadeen A
AU  - Dorian P
Y1  - 2011/07//
N1  - Accession Number: 104805710. Language: English. Entry Date: 20110826. Revision Date: 20150711. Publication Type: Journal Article; editorial. Journal Subset: Biomedical; Blind Peer Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. NLM UID: 9602087. 
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Dietary Supplements
KW  - Fatty Acids, Omega-3 -- Therapeutic Use
KW  - Atrial Fibrillation -- Physiopathology
KW  - Diet
KW  - Cardiovascular System Physiology -- Drug Effects
SP  - 1032
EP  - 1033
JO  - Heart
JF  - Heart
JA  - HEART
VL  - 97
IS  - 13
PB  - BMJ Publishing Group
SN  - 1355-6037
AD  - Division of Cardiology, St Michael's Hospital, 30 Bond Street, 6-050Q, Toronto, ON M5B 1W8, Canada; dorianp@smh.toronto.on.ca.
U2  - PMID: 21487124.
DO  - 10.1136/hrt.2010.221507
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104805710&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103797447
T1  - Oral Presenters.
Y1  - 2015/05/02/May2015 Supplement
N1  - Accession Number: 103797447. Language: English. Entry Date: 20150519. Revision Date: 20160502. Publication Type: Journal Article. Supplement Title: May2015 Supplement. Journal Subset: Asia; Australia & New Zealand; Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed. Special Interest: Gerontologic Care. NLM UID: 9808874. 
KW  - Aged
KW  - Aged, 80 and Over
KW  - Male
KW  - Female
KW  - Vitamin D Deficiency -- Physiopathology
KW  - Mortality -- Evaluation
KW  - Testosterone -- Analysis
KW  - Prostatic Neoplasms -- Epidemiology
KW  - Accidental Falls -- Etiology
KW  - Treatment Outcomes -- Evaluation
KW  - Polypharmacy -- Evaluation
KW  - Dementia -- Diagnosis
KW  - Dementia -- Therapy
KW  - Geriatric Assessment
KW  - Socialization -- Evaluation
KW  - Hip Fractures
KW  - Energy Intake -- Evaluation
KW  - Dehydration -- Complications
KW  - Health Resource Utilization
KW  - Automobile Driving
KW  - Intracranial Hemorrhage -- Symptoms
KW  - Recreational Therapy -- Evaluation
KW  - Fractures -- Risk Factors
KW  - Vitamin D -- Analysis
KW  - Hypotension, Orthostatic -- Drug Therapy
KW  - Delirium -- Diagnosis
KW  - Fractures -- Surgery
KW  - Femoral Fractures
KW  - Patient Discharge
KW  - Restraint, Physical
KW  - Readmission -- Evaluation
KW  - Resuscitation Orders -- Evaluation
KW  - Resuscitation, Cardiopulmonary
KW  - Oral Health
KW  - Delirium -- Drug Therapy
KW  - Transplant Donors
KW  - Palliative Care
KW  - Quality of Life -- Evaluation
KW  - Geriatric Nutrition
KW  - Parkinson Disease -- Therapy
KW  - Deep Brain Stimulation -- Evaluation
KW  - Physical Therapy Assessment
KW  - Aged, Hospitalized
KW  - Constipation -- Drug Therapy
KW  - Diabetes Mellitus, Type 2 -- Complications
KW  - Weight Loss -- Evaluation
KW  - Exercise -- Evaluation
KW  - Quality of Health Care -- Evaluation
KW  - Muscles
KW  - Patient Education -- Evaluation
KW  - Fractures -- Economics
KW  - Femoral Fractures -- Therapy
KW  - Hip Fractures -- Therapy
KW  - Antipsychotic Agents -- Adverse Effects
KW  - Professional Development -- Evaluation
KW  - Accidental Falls -- Prevention and Control
KW  - Venous Thromboembolism -- Physiopathology
KW  - Respiratory Tract Infections -- Therapy
KW  - Atrial Fibrillation
KW  - Blood -- Analysis
KW  - Osteoporosis -- Diagnosis
KW  - Blood Pressure Devices -- Evaluation
SP  - 17
EP  - 50
JO  - Australasian Journal on Ageing
JF  - Australasian Journal on Ageing
JA  - AUSTRALAS J AGEING
VL  - 34
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 1440-6381
DO  - 10.1111/ajag.12241
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103797447&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 113444931
T1  - Parachute-Like Mitral Valve with Symptomatic Stenosis-Imaging with Transthoracic and Transesophageal Three-Dimensional Echocardiography and Treatment Implications.
AU  - Wierzbowska-Drabik, Karina
AU  - Kasprzak, Jarosław Damian
Y1  - 2016/03//
N1  - Accession Number: 113444931. Language: English. Entry Date: 20160307. Revision Date: 20160307. Publication Type: Article. Journal Subset: Allied Health; Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 8511187. 
KW  - Mitral Valve Stenosis -- Diagnosis
KW  - Echocardiography, Three-Dimensional -- Utilization
KW  - Echocardiography, Transesophageal -- Utilization
KW  - Mitral Valve -- Abnormalities
KW  - Echocardiography, Doppler, Color -- Utilization
KW  - Middle Age
KW  - Female
KW  - Atrial Fibrillation -- Etiology
KW  - Heart Murmurs -- Etiology
KW  - Exercise -- Adverse Effects
KW  - Mitral Valve Stenosis -- Ultrasonography
KW  - Referral and Consultation
SP  - 496
EP  - 498
JO  - Echocardiography
JF  - Echocardiography
JA  - ECHOCARDIOGRAPHY
VL  - 33
IS  - 3
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 0742-2822
AD  - Department of Cardiology, Medical University of Lodz
DO  - 10.1111/echo.13114
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=113444931&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106068409
T1  - Pathoaetiology, epidemiology and diagnosis of hypertension.
AU  - Brown M
AU  - Haydock S
Y1  - 2000/06/03/Jun2000 Supplement 2
N1  - Accession Number: 106068409. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article. Supplement Title: Jun2000 Supplement 2. Journal Subset: Australia & New Zealand; Biomedical; Peer Reviewed. NLM UID: 7600076. 
SP  - 1
EP  - 12
JO  - Drugs
JF  - Drugs
JA  - DRUGS
VL  - 59
IS  - 6
PB  - Springer Science & Business Media B.V.
AB  - Hypertension is currently defined in terms of levels of blood pressure associated with increased cardiovascular risk. A cut-off of 140/90mm Hg is accepted as a threshold level above which treatment should at least be considered. This would give a prevalence of hypertension of about 20% of the adult population in most developed countries. Hypertension is associated with increased risk of stroke, myocardial infarction, atrial fibrillation, heart failure, peripheral vascular disease and renal impairment. Hypertension results from the complex interaction of genetic factors and environmental influences. Many of the genetic factors remain to be discovered, but environmental influences such as salt intake, diet and alcohol form the basis of nonpharmacological methods of blood pressure reduction. Investigation of the individual hypertensive patient aims to identify possible secondary causes of hypertension and also to assess the individual's overall cardiovascular risk, which determines the need for prompt and aggressive therapy. Cardiovascular risk can be determined from target organ damage to the eyes, heart and kidneys; other medical conditions associated with increased risk; and lifestyle factors such as obesity and smoking. Secondary causes of hypertension are individually rare. Screening tests should be initially simple, with more expensive and invasive tests reserved for those in whom a secondary cause is suspected or who have atypical features to their presentation. The main determinants of blood pressure are cardiac output and peripheral resistance. The typical haemodynamic finding in patients with established hypertension is of normal cardiac output and increased peripheral resistance. Treatment of hypertension should initially use nonpharmacological methods. Selection of initial drug therapy should be based upon the strength of evidence for reduction of cardiovascular mortality in controlled clinical trials, and should also take into account coexisting medical conditions that favour or limit the usefulness of any given drug. Given this approach, it would be reasonable to use a thiazide diuretic and/or a [beta]-blocker as first-line therapy unless there are indications to the contrary. Individual response to given drug classes is highly variable and is related to the underlying variability in the abnormal pathophysiology. There are data to suggest that the renin-angiotensin system is more important in young patients. The targeting of this system in patients under the age of 50 years with a [beta]-blocker (or ACE inhibitor), and the use of a thiazide diuretic (or calcium antagonist) in patients over 50 years, may enable blood pressure to be controlled more quickly.
SN  - 0012-6667
U2  - PMID: 10678592.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106068409&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105230113
T1  - Patient perspectives on taking vitamin K antagonists: a qualitative study in the UK, USA and Spain.
AU  - Wild D
AU  - Murray M
AU  - Donatti C
Y1  - 2009/10//
N1  - Accession Number: 105230113. Language: English. Entry Date: 20100129. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; UK & Ireland. Special Interest: Evidence-Based Practice. NLM UID: 101132257. 
KW  - Anticoagulants -- Pharmacodynamics
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Venous Thromboembolism -- Drug Therapy
KW  - Vitamin K -- Antagonists and Inhibitors
KW  - Adult
KW  - Aged
KW  - Aged, 80 and Over
KW  - Anticoagulants -- Adverse Effects
KW  - Atrial Fibrillation -- Physiopathology
KW  - Data Collection
KW  - Diet
KW  - Drug Monitoring -- Methods
KW  - Female
KW  - Great Britain
KW  - Human
KW  - International Normalized Ratio
KW  - Male
KW  - Middle Age
KW  - Patient Satisfaction
KW  - Spain
KW  - United States
KW  - Venous Thromboembolism -- Physiopathology
SP  - 467
EP  - 474
JO  - Expert Review of Pharmacoeconomics & Outcomes Research
JF  - Expert Review of Pharmacoeconomics & Outcomes Research
JA  - EXPERT REV PHARMACOECON OUTCOMES RES
VL  - 9
IS  - 5
CY  - Philadelphia, Pennsylvania
PB  - Taylor & Francis Ltd
SN  - 1473-7167
AD  - Oxford Outcomes Ltd, Seacourt Tower, West Way, Oxford, OX2 OJJ, UK. diane.wild@oxfordoutcomes.com.
U2  - PMID: 19817530.
DO  - 10.1586/erp.09.48
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105230113&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107808223
T1  - Patient Perspectives: Long-Distance Running and Mountain Biking in Permanent Atrial Fibrillation.
AU  - McCullough, Michael
Y1  - 2014/12//
N1  - Accession Number: 107808223. Language: English. Entry Date: 20141227. Revision Date: 20150712. Publication Type: Journal Article; pictorial. Journal Subset: Allied Health; Biomedical; USA. Special Interest: Laboratory Diagnosis. NLM UID: 101174623. 
KW  - Running, Distance
KW  - Atrial Fibrillation
KW  - Cycling
KW  - Endurance Sports
KW  - Physician-Patient Relations
KW  - Life Experiences
KW  - Adaptation, Physiological
KW  - Adaptation, Psychological
SP  - 1
EP  - 11
JO  - EP Lab Digest
JF  - EP Lab Digest
JA  - EP LAB DIGEST
VL  - 14
IS  - 12
CY  - Malvern, Pennsylvania
PB  - HMP Communications
SN  - 1535-2226
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107808223&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107904213
T1  - Patient satisfaction with warfarin- and non-warfarin-containing thromboprophylaxis regimens for atrial fibrillation.
AU  - Coleman, Craig I
AU  - Coleman, Stacey M
AU  - Vanderpoel, Julie
AU  - Nelson, Winnie
AU  - Colby, Jennifer A
AU  - Scholle, Jennifer M
AU  - Kluger, Jeffrey
Y1  - 2013/06//2013 Jun
N1  - Accession Number: 107904213. Language: English. Entry Date: 20140509. Revision Date: 20160805. Publication Type: journal article; research. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9501229. 
KW  - Anticoagulants -- Therapeutic Use
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Patient Satisfaction
KW  - Thrombosis -- Drug Therapy
KW  - Thrombosis -- Prevention and Control
KW  - Warfarin -- Therapeutic Use
KW  - Aged
KW  - Anticoagulants -- Pharmacodynamics
KW  - Atrial Fibrillation -- Complications
KW  - Atrial Fibrillation -- Physiopathology
KW  - Blood Coagulation -- Drug Effects
KW  - Female
KW  - Human
KW  - Male
KW  - Thrombosis -- Complications
KW  - Thrombosis -- Physiopathology
KW  - Warfarin -- Pharmacodynamics
SP  - 878
EP  - 881
JO  - Journal of Investigative Medicine (Decker Publishing)
JF  - Journal of Investigative Medicine (Decker Publishing)
JA  - J INVEST MED
VL  - 61
IS  - 5
CY  - Hamilton, Ontario
PB  - Decker Publishing
AB  - Objective: To compare patient-reported limitations, concerns, and burdens in those receiving and not receiving warfarin for thromboprophylaxis in atrial fibrillation (AF).Methods: We conducted a cross-sectional survey study of patients with AF receiving thromboprophylaxis for stroke prevention. Patients were administered the validated Anti-Clot Treatment Scale (ACTS). Mean scores of patients receiving and not receiving warfarin were compared for each ACTS item, and for the Burden and Benefit subscales.Results: From July 2010 to August 2011, 80 patients with AF were administered the survey, with 65 patients receiving a regimen containing warfarin and 15 patients not receiving a regimen containing warfarin. Six of the 17 individual questions depicting patient- perceived limitations in physical activity due to bleeding, limitations on diet, feelings of inconvenience of occasional aspects of thromboprophylaxis therapy, and frustration, and burden had less favorable scores in the warfarin-managed patients compared with the patients not receiving warfarin (P < 0.05 for all). Mean ACTS Burden scores were more favorable in the no-warfarin group (44.5 ± 6.4) compared with the warfarin group (39.8 ± 8.0; P = 0.003). No difference was seen between the 2 groups on the ACTS Benefits score (11.1 ± 3.4 vs 10.4 ± 3.7; P = 0.38).Conclusion: Patients with AF receiving warfarin may have less favorable feelings regarding thromboprophylaxis versus those receiving non-warfarin thromboprophylaxis. Patients report having more limitations and having greater feelings of burden on warfarin.
SN  - 1081-5589
AD  - From the *University of Connecticut School of Pharmacy, Storrs; tDepartment of Cardiology, Hartford Hospital, Hartford, CT; tJanssen Scientific Affairs, LLC, Raritan, NJ.
U2  - PMID: 23524987.
DO  - 10.2310/JIM.0b013e31828df1bf
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107904213&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105521172
T1  - Physical activity and atrial fibrillation.
Y1  - 2009/03//2009 Mar-Apr
N1  - Accession Number: 105521172. Language: English. Entry Date: 20090626. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Original Study: Mozaffarian D, Furberg CD, Psaty BM, and Siscovick D. Physical activity and incidence of atrial fibrillation in older adults: the cardiovascular health study. Circulation 2008; 118: 800-7. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Obstetric Care; Women's Health. NLM UID: 9890434. 
KW  - Atrial Fibrillation -- Epidemiology
KW  - Exercise
KW  - Physical Activity
KW  - Aged
KW  - Incidence
KW  - Prospective Studies
SP  - 11
EP  - 12
JO  - ACOG Clinical Review
JF  - ACOG Clinical Review
JA  - ACOG CLIN REV
VL  - 14
IS  - 2
CY  - Washington, District of Columbia
PB  - American Congress of Obstetrics & Gynecology
SN  - 1085-6862
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105521172&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105699720
T1  - Physical activity and the risk of atrial fibrillation.
AU  - DiMarco JP
Y1  - 2008/10//
N1  - Accession Number: 105699720. Language: English. Entry Date: 20081128. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Original Study: Mozaffarian D, Furberg CD, Psaty BM, Siscovick D. Physical activity and incidence of atrial fibrillation in older adults: the cardiovascular health study. (CIRCULATION) 8/19/2008; 118 (8): 800-807. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Gerontologic Care. NLM UID: 9880022. 
KW  - Atrial Fibrillation -- Risk Factors -- In Old Age
KW  - Physical Activity
KW  - Aged
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Exercise
SP  - 90
EP  - 90
JO  - Clinical Cardiology Alert
JF  - Clinical Cardiology Alert
JA  - CLIN CARDIOL ALERT
VL  - 27
IS  - 10
CY  - Atlanta, Georgia
PB  - AHC Media LLC
SN  - 0741-4218
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105699720&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109831317
T1  - Physical activity as a determinant of fasting and 2-h post-challenge glucose: a prospective cohort analysis of the NAVIGATOR trial.
AU  - Yates, T.
AU  - Davies, M. J.
AU  - Haffner, S. M.
AU  - Schulte, P. J.
AU  - Thomas, L.
AU  - Huffman, K. M.
AU  - Bales, C. W.
AU  - Preiss, D.
AU  - Califf, R. M.
AU  - Holman, R. R.
AU  - McMurray, J. J. V.
AU  - Bethel, M. A.
AU  - Tuomilehto, J.
AU  - Kraus, W. E.
Y1  - 2015/08//
N1  - Accession Number: 109831317. Language: English. Entry Date: 20150720. Revision Date: 20160801. Publication Type: Journal Article; equations & formulas; research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 8500858. 
KW  - Physical Activity -- Evaluation
KW  - Fasting
KW  - Glucose Tolerance Test -- Evaluation
KW  - Prospective Studies
KW  - Human
KW  - Blood Glucose -- Analysis
KW  - Research Subject Recruitment
KW  - Pedometers
KW  - Exercise
KW  - Diabetes Mellitus, Type 2 -- Risk Factors
KW  - Life Style Changes
KW  - Middle Age
KW  - Geographic Locations
KW  - Race Factors
KW  - Comorbidity
KW  - Heart Failure -- Diagnosis
KW  - Coronary Disease
KW  - Lung Diseases
KW  - Body Mass Index -- Evaluation
KW  - Blood Pressure Determination
KW  - Systolic Pressure -- Evaluation
KW  - Diastolic Pressure -- Evaluation
KW  - Atrial Fibrillation -- Diagnosis
KW  - Lipoproteins, HDL
KW  - Lipoproteins, LDL
KW  - Triglycerides -- Blood
KW  - Glomerular Filtration Rate
SP  - 1090
EP  - 1096
JO  - Diabetic Medicine
JF  - Diabetic Medicine
JA  - DIABETIC MED
VL  - 32
IS  - 8
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 0742-3071
AD  - NIHR Leicester-Loughborough Diet, Lifestyle, and Physical Activity Biomedical Research Unit; Diabetes Research Centre, College of Medicine, Biological Sciences and Psychology, University of Leicester
AD  - Department of Medicine, University of Texas Health Science Center
AD  - Duke Clinical Research Institute, Duke University School of Medicine
AD  - Duke Clinical Research Institute, Duke University School of Medicine; Durham VA Medical Center
AD  - British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow
AD  - Diabetes Trials Unit, University of Oxford
AD  - Centre for Vascular Prevention, Danube University Krems; South Ostrobothnia Central Hospital; King Abdulaziz University
U2  - PMID: 25818859.
DO  - 10.1111/dme.12762
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109831317&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 116247634
T1  - Physician and Patient Preferences for Nonvalvular Atrial Fibrillation Therapies.
AU  - Shafrin, Jason
AU  - Bruno, Amanda
AU  - MacEwan, Joanna P.
AU  - Campinha-Bacote, Avrita
AU  - Trocio, Jeffrey
AU  - Shah, Manan
AU  - Tan, Wilson
AU  - Romley, John A.
Y1  - 2016/06//
N1  - Accession Number: 116247634. Language: English. Entry Date: In Process. Revision Date: 20160708. Publication Type: Article. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 100883818. 
SP  - 451
EP  - 459
JO  - Value in Health
JF  - Value in Health
JA  - VALUE HEALTH
VL  - 19
IS  - 4
CY  - New York, New York
PB  - Elsevier Science
AB  - Objectives: The objective of this study was to compare patient and physician preferences for different antithrombotic therapies used to treat nonvalvular atrial fibrillation (NVAF).Methods: Patients diagnosed with NVAF and physicians treating such patients completed 12 discrete choice questions comparing NVAF therapies that varied across five attributes: stroke risk, major bleeding risk, convenience (no regular blood testing/dietary restrictions), dosing frequency, and patients' out-of-pocket cost. We used a logistic regression to estimate the willingness-to-pay (WTP) value for each attribute.Results: The 200 physicians surveyed were willing to trade off $38 (95% confidence interval [CI] $22 to $54] in monthly out-of-pocket cost for a 1% (absolute) decrease in stroke risk, $14 (95% CI $8 to $21) for a 1% decrease in major bleeding risk, and $34 (95% CI $9 to $60) for more convenience. The WTP value among 201 patients surveyed was $30 (95% CI $18 to $42) for reduced stroke risk, $16 (95% CI $9 to $24) for reduced bleeding risk, and -$52 (95% CI -$96 to -6) for convenience. The WTP value for convenience among patients using warfarin was $9 (95% CI $1 to $18) for more convenience, whereas patients not currently on warfarin had a WTP value of -$90 (95% CI -$290 to -$79). Both physicians' and patients' WTP value for once-daily dosing was not significantly different from zero. On the basis of survey results, 85.0% of the physicians preferred novel oral anticoagulants (NOACs) to warfarin. NOACs (73.0%) were preferred among patients using warfarin, but warfarin (78.2%) was preferred among patients not currently using warfarin. Among NOACs, both patients and physicians preferred apixaban.Conclusions: Both physicians and patients currently using warfarin preferred NOACs to warfarin. Patients not currently using warfarin preferred warfarin over NOACs because of an apparent preference for regular blood testing/dietary restrictions.
SN  - 1524-4733
AD  - Precision Health Economics, Los Angeles, CA, USA
AD  - Bristol-Myers Squibb, Plainsboro, NJ, USA
AD  - Pfizer, Inc., New York, NY, USA
AD  - University of Southern California, Los Angeles, CA, USA
U2  - PMID: 27325337.
DO  - 10.1016/j.jval.2016.01.001
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=116247634&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106126400
T1  - POEMs & tips from other journals. Tips.
AU  - Miller KE
AU  - Wellbery C
AU  - Carter C
AU  - Walling AD
AU  - Lin KW
A2  - Ebell M
Y1  - 2006/11//11/1/2006
N1  - Accession Number: 106126400. Language: English. Entry Date: 20070727. Revision Date: 20150711. Publication Type: Journal Article; commentary; tables/charts. Original Study: Howard BV, Van Horn L, Hsia J, Manson JE, Stefanick ML, Wassertheil-Smoller S, et al. Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. (JAMA) 2/8/2006; 295 (6): 655-666. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 1272646. 
KW  - Acetaminophen -- Adverse Effects
KW  - Adolescence
KW  - Adult
KW  - Aged
KW  - Aged, 80 and Over
KW  - Alternative Therapies -- Utilization
KW  - Antibiotics -- Therapeutic Use
KW  - Anticoagulants -- Therapeutic Use
KW  - Antiinfective Agents, Fluoroquinolone -- Adverse Effects
KW  - Antioxidants -- Administration and Dosage
KW  - Aspirin -- Administration and Dosage
KW  - Aspirin -- Therapeutic Use
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Atrial Fibrillation -- Therapy
KW  - Car Safety Devices -- Utilization
KW  - Cardiovascular Diseases -- Drug Therapy
KW  - Cardiovascular Risk Factors -- Prevention and Control
KW  - Stroke -- Prevention and Control
KW  - Clopidogrel Bisulfate -- Therapeutic Use
KW  - Community-Acquired Pneumonia -- Drug Therapy
KW  - Diphenhydramine -- Administration and Dosage
KW  - Early Intervention -- Utilization
KW  - Electrocardiography -- Standards
KW  - Energy Metabolism -- Evaluation
KW  - Female
KW  - Glycemic Control -- Drug Effects
KW  - Infant
KW  - Infant, Newborn
KW  - Liver -- Drug Effects
KW  - Macular Degeneration -- Diagnosis
KW  - Macular Degeneration -- Therapy
KW  - Maternal Exposure -- Adverse Effects
KW  - Mediterranean Diet -- Utilization
KW  - Menopause
KW  - Mercury -- Adverse Effects
KW  - Metronidazole -- Therapeutic Use
KW  - Middle Age
KW  - Mortality -- Prevention and Control
KW  - Mortality -- Risk Factors
KW  - Myocardial Infarction -- Mortality
KW  - Myocardial Infarction -- Prevention and Control
KW  - Obesity -- Complications
KW  - Physical Activity -- Utilization
KW  - Pneumonia -- Therapy
KW  - Pre-Eclampsia -- Prevention and Control
KW  - Residential Facilities -- Standards
KW  - Seafood -- Therapeutic Use
KW  - Sleep -- Drug Effects
KW  - United States
KW  - Vaginosis, Bacterial -- Drug Therapy
KW  - Vitamins -- Administration and Dosage
KW  - Warfarin -- Administration and Dosage
KW  - Wounds and Injuries -- Prevention and Control
SP  - 1603
EP  - 1610
JO  - American Family Physician
JF  - American Family Physician
JA  - AM FAM PHYSICIAN
VL  - 74
IS  - 9
CY  - Skokie, Illinois
PB  - American Academy of Family Physicians
SN  - 0002-838X
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106126400&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105912699
T1  - Possible effects of acupuncture on atrial fibrillation and post-herpetic neuralgia - a case report.
AU  - Valaskatgis P
AU  - Macklin EA
AU  - Schachter SC
AU  - Wayne PM
Y1  - 2008/03//
N1  - Accession Number: 105912699. Language: English. Entry Date: 20080516. Revision Date: 20150711. Publication Type: Journal Article; case study; research; tables/charts. Journal Subset: Alternative/Complementary Therapies; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Special Interest: Gerontologic Care; Pain and Pain Management. Grant Information: Supported by Grant # 5 U19 AT002022-02 from the National Center for Complementary and Alternative Medicine (NCCAM). NLM UID: 9304117. 
KW  - Acupuncture -- In Old Age
KW  - Atrial Fibrillation -- Therapy -- In Old Age
KW  - Neuralgia, Postherpetic -- Therapy -- In Old Age
KW  - Acupuncture Points -- In Old Age
KW  - Aged
KW  - Alternative Therapies -- In Old Age
KW  - Confidence Intervals
KW  - Data Analysis Software
KW  - Descriptive Statistics
KW  - Female
KW  - Funding Source
KW  - Massachusetts
KW  - Medicine, Chinese Traditional -- In Old Age
KW  - Pain Measurement
KW  - Prospective Studies
KW  - Treatment Outcomes -- In Old Age
KW  - Two-Tailed Test
KW  - Human
SP  - 51
EP  - 56
JO  - Acupuncture in Medicine
JF  - Acupuncture in Medicine
JA  - ACUPUNCTURE MED
VL  - 26
IS  - 1
PB  - BMJ Publishing Group
AB  - A 72 year old female with a main complaint of severe post-herpetic neuralgia and a secondary complaint of atrial fibrillation (AF) received two series of acupuncture treatments totalling 20 treatments over a four month period. Her standard medical treatment remained unchanged. The primary focus of the acupuncture was pain relief; however, two acupuncture points (PC6, SP4) were included in both treatment series because of possible effects on both costal or chest pain and cardiac arrhythmias, according to Traditional Chinese Medicine (TCM) teaching and limited research. As recorded by her pacemaker, estimated weekly episodes of AF in the patient decreased significantly, and percentage time in AF decreased with borderline statistical significance, from the pretreatment estimates during the second series of treatments (weekly AF episode estimates: pretreatment =71.4; second series =16.5, difference estimates =-54.9, 95% CI -6.5 to -103.3, P=0.02; percentage time in AF estimates: pretreatment =30.6; 2 second series =18.0, difference estimates = -12.6, 95% CI 0.9 to -26.0, P=0.08). The pain levels were also significantly reduced following the acupuncture treatment series by more than 67%. Further studies are warranted to further explore these observations of a possible effect of acupuncture on both atrial fibrillation and post-herpetic neuralgia.
SN  - 0964-5284
AD  - Senior Professor, New England School of Medicine, Newton, MA, USA
U2  - PMID: 18356799.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105912699&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104005950
T1  - Preadmission interventions to prevent postoperative complications in older cardiac surgery patients: A systematic review.
AU  - Ettema, Roelof G. A.
AU  - Van Koeven, Heleen
AU  - Peelen, Linda M.
AU  - Kalkman, Cor J.
AU  - Schuurmans, Marieke J.
Y1  - 2014/02//
N1  - Accession Number: 104005950. Language: English. Entry Date: 20140130. Revision Date: 20150820. Publication Type: Journal Article; research; systematic review; tables/charts. Journal Subset: Core Nursing; Europe; Nursing; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice; Patient Safety. NLM UID: 0400675. 
KW  - Postoperative Complications -- Prevention and Control
KW  - Heart Surgery
KW  - Preoperative Care
KW  - Patient Safety
KW  - Systematic Review
KW  - Human
KW  - Depression
KW  - Length of Stay
KW  - Surgical Wound Infection -- Prevention and Control
KW  - Skin Preparation, Surgical
KW  - Chlorhexidine -- Therapeutic Use
KW  - Dietary Supplements
KW  - Fatty Acids, Unsaturated
KW  - Snowball Sample
KW  - Medline
KW  - Embase
KW  - Cochrane Library
KW  - CINAHL Database
KW  - Psycinfo
KW  - Surgical Patients
KW  - Breathing Exercises
KW  - Relaxation Techniques
KW  - Preoperative Education
KW  - Cognitive Therapy
KW  - Motivational Interviewing
SP  - 251
EP  - 260
JO  - International Journal of Nursing Studies
JF  - International Journal of Nursing Studies
JA  - INT J NURS STUD
VL  - 51
IS  - 2
CY  - Philadelphia, Pennsylvania
PB  - Elsevier Inc.
AB  - Objective(s): The literature on postoperative complications in cardiac surgery patients shows high incidences of postoperative complications such as delirium, depression, pressure ulcer, infection, pulmonary complications and atrial fibrillation. These complications are associated with functional and cognitive decline and a decrease in the quality of life after discharge. Several studies attempted to prevent one or more postoperative complications by preoperative interventions. Here we provide a compre- hensive overview of both single and multiple component preadmission interventions designed to prevent postoperative complications. Methods: We systematically reviewed the literature following the PRISMA statement guidelines. Results: Of 1335 initial citations, 31 were subjected to critical appraisal. Finally, 23 studies were included, of which we derived a list of interventions that can be applied in the preadmission period to effectively reduce postoperative depression, infection, pulmonary complications, atrial fibrillation, prolonged intensive care unit stay and hospital stay in older elective cardiac surgery patients. No high quality studies were found describing effective interventions to prevent postoperative delirium. We did not find studies specifically targeting the prevention of pressure ulcers in this patient population. Conclusions: Multi-component approaches that include different single interventions have the strongest effect in preventing postoperative depression, pulmonary complications, prolonged intensive care unit stay and hospital stay. Postoperative infection can be best prevented by disinfection with chlorhexidine combined with immune-enhancing nutritional supplements. Atrial fibrillation might be prevented by ingestion of N-3 polyunsaturated fatty acids. High quality studies are urgently needed to evaluate preadmission preventive strategies to reduce postoperative delirium or pressure ulcers in older elective cardiac surgery patients.
SN  - 0020-7489
AD  - Nursing and Paramedical Care for People Chronic Illnesses, University of Applied Science Utrecht, Faculty of Health Care, Bolognalaan 101, 3584 CJ Utrecht, The Netherlands; Julius Center for Health Sciences and Primary Care, Department of Epidemiology, University Medical Center Utrecht, P.O. Box 85500, 3508 GA Utrecht, The Netherlands
AD  - Division of Anesthesiology, Intensive Care and Emergency Medicine, University Medical Center Utrecht, P.O. Box 85500, 3508 GA Utrecht, The Netherlands
AD  - Julius Center for Health Sciences and Primary Care, Department of Epidemiology, University Medical Center Utrecht, P.O. Box 85500, 3508 GA Utrecht, The Netherlands
AD  - Professor of Anesthesiology, Division of Anesthesiology, Intensive Care and Emergency Medicine, University Medical Center Utrecht, P.O. Box 85500, 3508 GA Utrecht, The Netherlands
AD  - Nursing and Paramedical Care for People Chronic Illnesses, University of Applied Science Utrecht, Faculty of Health Care, Bolognalaan 101, 3584 CJ Utrecht, The Netherlands; Professor of Nursing Science, Department of Rehabilitation, Nursing Science & Sports, University Medical Center Utrecht, P.O. Box 85500, 3508 GA Utrecht, The Netherlands
U2  - PMID: 23796313.
DO  - 10.1016/j.ijnurstu.2013.05.011
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106221475
T1  - Preventing cardiovascular disease in women.
AU  - Hayes SN
Y1  - 2006/10/15/
N1  - Accession Number: 106221475. Language: English. Entry Date: 20070119. Revision Date: 20150711. Publication Type: Journal Article; CEU; consumer/patient teaching materials; exam questions; tables/charts. Commentary: Plate DS, Hughes S. The heart of women's health. (AM FAM PHYSICIAN) 10/15/2006; 74 (8): 1285-1286. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Evidence-Based Practice; Women's Health. NLM UID: 1272646. 
KW  - Cardiovascular Diseases -- Prevention and Control
KW  - Adrenergic Beta-Antagonists -- Administration and Dosage
KW  - Aged
KW  - Angiotensin-Converting Enzyme Inhibitors -- Administration and Dosage
KW  - Antioxidants -- Therapeutic Use
KW  - Aspirin -- Administration and Dosage
KW  - Aspirin -- Adverse Effects
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Blood Pressure
KW  - Cardiovascular Diseases -- Psychosocial Factors
KW  - Cardiovascular Risk Factors
KW  - Stroke -- Prevention and Control
KW  - Depression -- Drug Therapy
KW  - Diabetes Mellitus -- Drug Therapy
KW  - Diet
KW  - Education, Continuing (Credit)
KW  - Fatty Acids, Omega-3 -- Therapeutic Use
KW  - Female
KW  - Hyperlipidemia -- Diet Therapy
KW  - Hyperlipidemia -- Drug Therapy
KW  - Life Style
KW  - Lipoproteins, HDL Cholesterol
KW  - Lipoproteins, LDL Cholesterol
KW  - Middle Age
KW  - Obesity
KW  - Patient Education
KW  - Physical Activity
KW  - Physicians, Family
KW  - Practice Guidelines
KW  - Professional Practice, Evidence-Based
KW  - Risk Assessment -- Classification
KW  - Smoking Cessation
KW  - Warfarin -- Administration and Dosage
SP  - 1331
EP  - 1277
JO  - American Family Physician
JF  - American Family Physician
JA  - AM FAM PHYSICIAN
VL  - 74
IS  - 8
CY  - Skokie, Illinois
PB  - American Academy of Family Physicians
AB  - Cardiovascular disease (CVD) has been the primary cause of death in women for almost a century, and more women than men have died of CVD every year since 1984. Although CVD incidence can be reduced by adherence to a heart-healthy lifestyle and detection and treatment of major risk factors, preventive recommendations have not been consistently or optimally applied to women. The American Heart Association guidelines for CVD prevention in women provide physicians with a clear plan for assessment and treatment of CVD risk and personalization of treatment recommendations. The emphasis of preventive efforts has shifted away from treatment of individual CVD risk factors in isolation toward assessment of a woman's overall or 'global' CVD risk. In addition to accounting for the presence or absence of preexisting coronary heart disease or its equivalents (e.g., diabetes, chronic kidney disease), cardiovascular risk can be further calculated with the Framingham risk score, which is based on age, sex, smoking history, and lipid and blood pressure levels. Intervention intensity and treatment goals are tailored to overall risk, with those at highest risk receiving the most intense risk-lowering interventions. Women at high risk for CVD and without contraindications should receive aspirin, beta blockers, and an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker in addition to pharmacologic therapy for hyperlipidemia, hypertension, and diabetes. Women who already are at optimal or low risk for CVD should be encouraged to maintain or further improve their healthy lifestyle practices. Optimal application of these preventive practices significantly reduces the burden of death and disability caused by heart attack and stroke in women.
SN  - 0002-838X
AD  - Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA. hayes.sharonne@mayo.edu
U2  - PMID: 17087427.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105790483
T1  - Preventing further vascular events after a stroke or transient ischaemic attack: an update on medical management.
AU  - Sudlow C
Y1  - 2008/06//
N1  - Accession Number: 105790483. Language: English. Entry Date: 20080815. Revision Date: 20150711. Publication Type: Journal Article; pictorial; review; tables/charts. Journal Subset: Biomedical; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Special Interest: Perioperative Care; Psychiatry/Psychology. NLM UID: 101130961. 
KW  - Cerebral Ischemia, Transient -- Complications
KW  - Recurrence -- Prevention and Control
KW  - Stroke -- Complications
KW  - Angiotensin-Converting Enzyme Inhibitors -- Therapeutic Use
KW  - Anticoagulants -- Therapeutic Use
KW  - Aspirin -- Therapeutic Use
KW  - Atrial Fibrillation -- Complications
KW  - Diabetes Mellitus -- Drug Therapy
KW  - Diet
KW  - Dietary Supplements
KW  - Diuretics, Thiazide -- Therapeutic Use
KW  - Early Intervention
KW  - Exercise
KW  - Hypercholesterolemia -- Drug Therapy
KW  - Hypertension -- Drug Therapy
KW  - Life Style Changes
KW  - Patient Selection
KW  - Platelet Aggregation Inhibitors -- Therapeutic Use
KW  - Smoking Cessation
KW  - Statins -- Administration and Dosage
KW  - Statins -- Therapeutic Use
KW  - Stroke -- Risk Factors
KW  - Treatment Delay
KW  - Treatment Duration
SP  - 141
EP  - 157
JO  - Practical Neurology (BMJ Publishing Group)
JF  - Practical Neurology (BMJ Publishing Group)
JA  - PRACT NEUROL
VL  - 8
IS  - 3
PB  - BMJ Publishing Group
AB  - After a stroke or transient ischaemic attack (TIA) there is a high risk of stroke, particularly in the early days and weeks, and of other serious vascular events. Several preventive medical treatments can reduce these risks; starting them as early as possible will maximise the absolute risk reduction, as long as the diagnosis is secure, there is no known or suspected net harm from treatment, and they are acceptable to the patient. Medical treatments with clear evidence of benefit include: lowering blood pressure after all types of stroke or TIA; lowering blood cholesterol with a statin after ischaemic stroke or TIA; antiplatelet treatment after ischaemic stroke or TIA; and warfarin instead of antiplatelet treatment in patients with ischaemic stroke or TIA who have atrial fibrillation and no contraindications to anticoagulation. Lifestyle changes (for example, stopping smoking, reducing excess alcohol intake, adopting a healthy diet) and careful management of diabetes are also important.
SN  - 1474-7758
AD  - Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK; cathie.sudlow@ed.ac.uk
U2  - PMID: 18502947.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105790483&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - CHAP
ID  - 105019049
CT  - Preventing stroke.
T1  - Preventing stroke.
Y1  - 2010/01//
N1  - Accession Number: 105019049. Language: English. Entry Date: 20101210. Revision Date: 20150711. Publication Type: Pamphlet Chapter; forms; pictorial; tables/charts. 
KW  - Stroke -- Prevention and Control
KW  - Stroke -- Risk Factors
KW  - Adult
KW  - Aged
KW  - Alcohol Drinking
KW  - Aspirin -- Therapeutic Use
KW  - Atrial Fibrillation
KW  - Body Mass Index
KW  - Carotid Arteries -- Ultrasonography
KW  - Cerebral Ischemia, Transient -- Prevention and Control
KW  - Cholesterol -- Blood
KW  - Contraceptive Agents -- Adverse Effects
KW  - Diabetes Mellitus
KW  - Diastolic Pressure
KW  - Diet
KW  - Female
KW  - Health Screening
KW  - Hormone Replacement Therapy
KW  - Hypercholesterolemia
KW  - Hypertension
KW  - Life Style Changes
KW  - Male
KW  - Middle Age
KW  - Myocardial Infarction
KW  - Perimenopausal Symptoms -- Drug Therapy
KW  - Physical Activity
KW  - Sleep Apnea, Obstructive
KW  - Smoking
KW  - Smoking Cessation
KW  - Systolic Pressure
KW  - Tobacco
KW  - Triglycerides -- Blood
KW  - Weight Control
SP  - 9
EP  - 17
JO  - Stroke: Preventing & Treating 'Brain Attack' (2010)
JF  - Stroke: Preventing & Treating 'Brain Attack' (2010)
CY  - Stamford, Connecticut
PB  - Harvard Health Publications
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105019049&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103801571
T1  - Prevention of atherosclerosis by Yindan Xinnaotong capsule combined with swimming in rats.
AU  - Jianlu Wang
AU  - Lan Wang
AU  - Hongjun Yang
AU  - Yun You
AU  - Haiyu Xu
AU  - Leilei Gong
AU  - Xiaojie Yin
AU  - Wandan Wang
AU  - Shuangrong Gao
AU  - Long Cheng
AU  - Rixin Liang
AU  - Fulong Liao
Y1  - 2015/04//
N1  - Accession Number: 103801571. Language: English. Entry Date: 20150522. Revision Date: 20150710. Publication Type: Journal Article; pictorial; research; tables/charts. Journal Subset: Alternative/Complementary Therapies; Biomedical; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Grant Information: This work was supported by the Chinese Drug Discovery Initiative Project (No. 2012ZX09201201).. NLM UID: 101088661. 
KW  - Atherosclerosis -- Prevention and Control
KW  - Swimming
KW  - Therapeutic Exercise
KW  - Atherosclerosis -- Therapy
KW  - Medicine, Chinese Traditional
KW  - Medicine, Herbal
KW  - Animal Studies
KW  - Rats
KW  - Lipids -- Blood
KW  - Carotid Arteries -- Pathology
KW  - Immunohistochemistry
KW  - Blood Viscosity
KW  - Nitric Oxide
KW  - Prostaglandins
KW  - Endothelins
KW  - Thromboxanes
KW  - Data Analysis Software
KW  - Two-Way Analysis of Variance
KW  - Post Hoc Analysis
KW  - Descriptive Statistics
KW  - Funding Source
SP  - 1
EP  - 13
JO  - BMC Complementary & Alternative Medicine
JF  - BMC Complementary & Alternative Medicine
JA  - BMC COMPLEMENT ALTERN MED
VL  - 15
IS  - 1
PB  - BioMed Central
AB  - Background: Yindan Xinnaotong capsule has been used for treating cardio-cerebrovascular diseases for several decades in China. Exercise training can protect against the development of atherosclerosis. The aim of the present study is to evaluate the joint effect of YXC and exercise on atherosclerosis in rats. Methods: A combined method involving low shear stress and a high-fat diet was used to establish the atherosclerosis model in rats. Partial ligation of the left common carotid artery was performed, and then the rats were divided into 9 treatment groups according to a 3 x 3 factorial design with two factors and three levels for each factor, swimming of 0, 0.5,1 h daily and YXC administration of 0,1, 2 g/kg p.o. daily. Next the interventions of swimming and YXC were executed for 8 weeks. After that, blood samples were collected to determine blood viscosity, plasma viscosity, haematocrit (HCT), fibrinogen (FIB), blood lipid profile (including total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), triglyceride (TG) and high-density lipoprotein-cholesterol (HDL-C)), nitric oxide (NO), 6-keto- prostaglandin (PG) F1α, endothelin (ET) and thromboxane (TX) B2. The common carotid arteries of the rats were harvested to examine pathological changes, wall thickness and circumference, and the expression of SM22α was assayed via immune-histochemistry. Results: The early pathological changes were observed. The joint effects of YXC and swimming showed significant changes in the examined parameters: (1) decreases in plasma viscosity, blood viscosity and FIB; (2) increases in NO and 6-keto-PGF1α; (3) decreases in ET and TXB2; and (4) decreases in LDL-C and TG. The combination of 2 g/kg YXC and 1 h of swimming led to synergistic decreases in LDL-C and TG. The interactive effect between YXC and swimming was obvious in decreasing wall thickness. Swimming alone was able to up-regulate the expression of SM22α. Conclusions: In conclusion, this study indicates that the combination of YXC and swimming may prevent atherosclerosis through a synergistic effect between YXC and swimming in improving blood circulation, hemorheological parameters, blood lipids levels and the vascular endothelium in rats. The vascular remodeling may be contributed to the prevention effects on AS by up-regulating SM22α.
SN  - 1472-6882
AD  - China Academy of Chinese Medical Sciences, Institute of Chinese Material Medical, Beijing, China
AD  - School of Traditional Chinese Medicine, Capita Medical University, Beijing, China
AD  - Chinese Academy of Medical Sciences, Institute of Medicinal Plant Development, Beijing, China; Guizhou Bailing Group Pharmaceutical Co., Ltd, Guizhou, China
DO  - 10.1186/s12906-015-0622-7
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106213670
T1  - Prevention of cardiovascular events in elderly people.
AU  - Andrawes WF
AU  - Bussy C
AU  - Belmin J
Y1  - 2005/10//
N1  - Accession Number: 106213670. Language: English. Entry Date: 20070112. Revision Date: 20150711. Publication Type: Journal Article; research; systematic review; tables/charts. Journal Subset: Australia & New Zealand; Biomedical; Peer Reviewed. NLM UID: 9102074. 
KW  - Cardiovascular Diseases -- Prevention and Control -- In Old Age
KW  - Aged
KW  - Aged, 80 and Over
KW  - Anticoagulants -- Therapeutic Use
KW  - Antihypertensive Agents -- Therapeutic Use
KW  - Antilipemic Agents -- Therapeutic Use
KW  - Carotid Artery Diseases -- Prevention and Control
KW  - Cerebral Ischemia -- Prevention and Control
KW  - Coronary Arteriosclerosis -- Prevention and Control
KW  - Fibrinolytic Agents -- Therapeutic Use
KW  - France
KW  - Medline
KW  - Human
SP  - 859
EP  - 876
JO  - Drugs & Aging
JF  - Drugs & Aging
JA  - DRUGS AGING
VL  - 22
IS  - 10
PB  - Springer Science & Business Media B.V.
AB  - Background and objective: Cardiovascular disease has been identified as the leading cause of morbidity and mortality in developed countries. Given the increase in life expectancy and the development of cardiovascular preventive measures, it has become increasingly important to detect and prevent cardiovascular diseases in the elderly. We reviewed the scientific literature concerning cardiovascular prevention to assess the importance of cardiovascular preventive measures in old (>/= 65 years of age) individuals.Methods: We undertook a systematic search for references relating to prevention of cardiovascular disease in the elderly, mainly ischaemic stroke, coronary artery disease and heart failure, on the MEDLINE database 1962-2005. For cardiovascular prevention by drugs or surgery, emphasis was placed on randomised controlled trials, review articles and meta-analyses. For cardiovascular prevention by lifestyle modification, major cohort studies were also considered.Results: Stroke, coronary heart disease and heart failure were found to be the main targets for cardiovascular prevention in published studies. Antihypertensive treatment has proven its efficacy in primary prevention of fatal or nonfatal stroke in hypertensive and high-risk patients >60 years of age, particularly through treatment of systolic hypertension. Systolic blood pressure reduction is equally important in the secondary prevention of stroke. Similarly, in nonvalvular atrial fibrillation, an adjusted dose of warfarin with a target International Normalized Ratio (INR) of between 2 to 3 prevents ischaemic stroke in elderly patients with an acceptable haemorrhagic risk but is still under prescribed. Antiplatelet agents are indicated in elderly patients with nonembolic strokes. Few large-scale studies have investigated the effect of HMG-CoA reductase inhibitors (statins) on stroke prevention in old individuals. To date, the largest trials suggest a beneficial effect for stroke prevention with use of statins in high-risk elderly subjects </=82 years of age. Carotid endarterectomy is indicated in carotid artery stenosis >70% and outcomes are even better in elderly than in younger patients. However, medical treatment is still the first-line treatment in asymptomatic elderly patients with <70% stenosis. In ischaemic heart disease, different trials in elderly individuals have shown that use of statins, antithrombotic agents, beta-adrenoceptor antagonists and ACE inhibitors plays an important role either in primary or in secondary cardiovascular prevention. Hormone replacement therapy has been used to treat climacteric symptoms and postmenopausal osteoporosis and was thought to confer a cardiovascular protection. However, controlled trials in elderly individuals changed this false belief when it was found that there was no benefit and even a harmful cardiovascular effect during the first year of treatment. Smoking cessation, regular physical activity and healthy diet are, as in younger individuals, appropriate and effective measures for preventing cardiovascular events in the elderly. Finally, antihypertensive treatment and influenza vaccination are useful for heart failure prevention in elderly individuals.Conclusions: Cardiovascular prevention should be more widely implemented in the elderly, including individuals aged >/= 75 years, and this might contribute to improved healthy status and quality of life in this growing population.
SN  - 1170-229X
U2  - PMID: 16245959.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106138424
T1  - Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: the American Academy of Neurology affirms the value of this guideline [corrected] [published erratum appears in STROKE 2007 Jan;38(1):207].
AU  - Goldstein LB
AU  - Adams R
AU  - Alberts MJ
AU  - Appel LJ
AU  - Brass LM
AU  - Bushnell CD
AU  - Culebras A
AU  - DeGraba TJ
AU  - Gorelick PB
AU  - Guyton JR
AU  - Hart RG
AU  - Howard G
AU  - Kelly-Hayes M
AU  - Nixon JV
AU  - Sacco RL
Y1  - 2006/06//2006 Jun
N1  - Accession Number: 106138424. Corporate Author: American Heart Association/American Stroke Association Stroke Council. Language: English. Entry Date: 20070824. Revision Date: 20150711. Publication Type: Journal Article; practice guidelines; review; tables/charts. Journal Subset: Allied Health; Biomedical; Peer Reviewed; USA. NLM UID: 0235266. 
KW  - Cerebral Ischemia -- Complications
KW  - Stroke -- Etiology
KW  - Stroke -- Prevention and Control
KW  - Stroke -- Risk Factors
KW  - Risk Assessment
SP  - 1583
EP  - 1633
JO  - Stroke (00392499)
JF  - Stroke (00392499)
JA  - STROKE
VL  - 37
IS  - 6
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - BACKGROUND AND PURPOSE: This guideline provides an overview of the evidence on various established and potential stroke risk factors and provides recommendations for the reduction of stroke risk. METHODS: Writing group members were nominated by the committee chair on the basis of each writer's previous work in relevant topic areas and were approved by the American Heart Association Stroke Council's Scientific Statement Oversight Committee. The writers used systematic literature reviews (covering the time period since the last review published in 2001 up to January 2005), reference to previously published guidelines, personal files, and expert opinion to summarize existing evidence, indicate gaps in current knowledge, and when appropriate, formulate recommendations based on standard American Heart Association criteria. All members of the writing group had numerous opportunities to comment in writing on the recommendations and approved the final version of this document. The guideline underwent extensive peer review before consideration and approval by the AHA Science Advisory and Coordinating Committee. RESULTS: Schemes for assessing a person's risk of a first stroke were evaluated. Risk factors or risk markers for a first stroke were classified according to their potential for modification (nonmodifiable, modifiable, or potentially modifiable) and strength of evidence (well documented or less well documented). Nonmodifiable risk factors include age, sex, low birth weight, race/ethnicity, and genetic factors. Well-documented and modifiable risk factors include hypertension, exposure to cigarette smoke, diabetes, atrial fibrillation and certain other cardiac conditions, dyslipidemia, carotid artery stenosis, sickle cell disease, postmenopausal hormone therapy, poor diet, physical inactivity, and obesity and body fat distribution. Less well-documented or potentially modifiable risk factors include the metabolic syndrome, alcohol abuse, drug abuse, oral contraceptive use, sleep-disordered breathing, migraine headache, hyperhomocysteinemia, elevated lipoprotein(a), elevated lipoprotein-associated phospholipase, hypercoagulability, inflammation, and infection. Data on the use of aspirin for primary stroke prevention are reviewed. CONCLUSIONS: Extensive evidence is available identifying a variety of specific factors that increase the risk of a first stroke and providing strategies for reducing that risk.
SN  - 0039-2499
U2  - PMID: 16675728.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109791135
T1  - Primary prevention of stroke by a healthy lifestyle in a high-risk group.
AU  - Larsson, Susanna C
AU  - Åkesson, Agneta
AU  - Wolk, Alicja
Y1  - 2015/06/02/
N1  - Accession Number: 109791135. Language: English. Entry Date: 20150904. Revision Date: 20150923. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0401060. 
KW  - Life Style
KW  - Preventive Health Care -- Methods
KW  - Behavior
KW  - Stroke -- Epidemiology
KW  - Stroke -- Prevention and Control
KW  - Aged
KW  - Aged, 80 and Over
KW  - Prospective Studies
KW  - Human
KW  - Male
KW  - Middle Age
KW  - Risk Factors
KW  - Stroke -- Diet Therapy
KW  - Sweden
SP  - 2224
EP  - 2228
JO  - Neurology
JF  - Neurology
JA  - NEUROLOGY
VL  - 84
IS  - 22
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - OBJECTIVE: To examine the impact of a healthy lifestyle on stroke risk in men at higher risk of stroke because of other cardiovascular diseases or conditions. METHODS: Our study population comprised 11,450 men in the Cohort of Swedish Men who had a history of hypertension, high cholesterol levels, diabetes, heart failure, or atrial fibrillation. Participants had completed a questionnaire about diet and lifestyle and were free from stroke and ischemic heart disease at baseline (January 1, 1998). We defined a healthy lifestyle as a low-risk diet (>=5 servings/d of fruits and vegetables and <30 g/d of processed meat), not smoking, >=150 min/wk of physical activity, body mass index of 18.5 to 25 kg/m(2), and low to moderate alcohol consumption (>0 to <=30 g/d). Ascertainment of stroke cases was accomplished through linkage with the National Inpatient Register and the Swedish Cause of Death Register. RESULTS: During a mean follow-up of 9.8 years, we ascertained 1,062 incident stroke cases. The risk of total stroke and stroke types decreased with increasing number of healthy lifestyle factors. The multivariable relative risk of total stroke for men who achieved all 5 healthy lifestyle factors compared with men who achieved 0 or 1 factor was 0.28 (95% confidence interval 0.14-0.55). The corresponding relative risks (95% confidence interval) were 0.31 (0.15-0.66) for ischemic stroke and 0.32 (0.04-2.51) for hemorrhagic stroke. CONCLUSIONS: A healthy lifestyle is associated with a substantially reduced risk of stroke in men at higher risk of stroke.
SN  - 0028-3878
U2  - PMID: 25934859.
DO  - 10.1212/WNL.0000000000001637
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106463242
T1  - Psychological and physical etiologies of heart palpitations.
AU  - Thompson J
Y1  - 2006/05//May/Jun2006
N1  - Accession Number: 106463242. Language: English. Entry Date: 20060630. Revision Date: 20150818. Publication Type: Journal Article; algorithm; CEU; exam questions; forms; pictorial; tables/charts; tracings. Journal Subset: Blind Peer Reviewed; Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 8702105. 
KW  - Arrhythmia -- Diagnosis
KW  - Arrhythmia -- Etiology
KW  - Alternative Therapies
KW  - Arrhythmia -- Therapy
KW  - Atrial Fibrillation
KW  - Caffeine
KW  - Diagnosis, Differential
KW  - Diagnosis, Laboratory
KW  - Diet
KW  - Echocardiography
KW  - Education, Continuing (Credit)
KW  - Electrocardiography
KW  - Menopause
KW  - Nurse Practitioners
KW  - Panic Disorder
KW  - Patient Education
KW  - Patient History Taking
KW  - Premature Ventricular Contractions
KW  - Questionnaires
KW  - Stress
KW  - Tachycardia
SP  - 107
EP  - 117
JO  - Holistic Nursing Practice
JF  - Holistic Nursing Practice
JA  - HOLISTIC NURS PRACT
VL  - 20
IS  - 3
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
SN  - 0887-9311
AD  - Department of Nursing, Quinnipiac University, Hamden, Conn,
U2  - PMID: 16672809.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105199284
T1  - QOF clinical indicators 2009/10: summary tables.
Y1  - 2010/03//2010 Mar
N1  - Accession Number: 105199284. Language: English. Entry Date: 20100625. Revision Date: 20150711. Publication Type: Journal Article; tables/charts. Journal Subset: Biomedical; Editorial Board Reviewed; Europe; Peer Reviewed; UK & Ireland. 
KW  - Primary Health Care
KW  - Quality Assurance
KW  - Quality of Health Care
KW  - Adrenergic Beta-Antagonists -- Therapeutic Use
KW  - Alcohol Drinking
KW  - Angina Pectoris -- Diagnosis
KW  - Angiotensin II Type I Receptor Blockers -- Therapeutic Use
KW  - Angiotensin-Converting Enzyme Inhibitors -- Therapeutic Use
KW  - Anticoagulants -- Therapeutic Use
KW  - Anticonvulsants -- Therapeutic Use
KW  - Asthma -- Diagnosis
KW  - Atrial Fibrillation -- Diagnosis
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Blood Pressure
KW  - Body Mass Index
KW  - Cardiovascular Diseases -- Prevention and Control
KW  - Cerebral Ischemia, Transient -- Diagnosis
KW  - Cholesterol -- Blood
KW  - Chronic Disease
KW  - Comorbidity
KW  - Contraception
KW  - Contraceptives, Oral
KW  - Contraceptives, Postcoital
KW  - Coronary Disease -- Diagnosis
KW  - Coronary Disease -- Prevention and Control
KW  - Dementia -- Diagnosis
KW  - Depression -- Diagnosis
KW  - Diabetes Mellitus
KW  - Diabetes Mellitus, Type 1
KW  - Diabetes Mellitus, Type 2
KW  - Diabetic Foot -- Prevention and Control
KW  - Diabetic Retinopathy -- Prevention and Control
KW  - Diet
KW  - Documentation
KW  - Dyspnea -- Diagnosis
KW  - Epilepsy -- Drug Therapy
KW  - Exercise Test
KW  - Fibrinolytic Agents -- Therapeutic Use
KW  - Forced Expiratory Volume
KW  - Heart Failure -- Diagnosis
KW  - Hemoglobin A -- Blood
KW  - Hypertension -- Diagnosis
KW  - Influenza Vaccine
KW  - Influenza -- Prevention and Control
KW  - Kidney Diseases
KW  - Multidisciplinary Care Team
KW  - Myocardial Infarction -- Diagnosis
KW  - Neoplasms -- Diagnosis
KW  - Physical Activity
KW  - Proteinuria -- Diagnosis
KW  - Pulmonary Disease, Chronic Obstructive -- Diagnosis
KW  - Smoking
KW  - Smoking Cessation
KW  - Smoking -- Prevention and Control
KW  - Stroke -- Diagnosis
KW  - Transdermal Patches, Drugs
KW  - Urinalysis
KW  - Ventricular Dysfunction, Left -- Complications
SP  - 53
EP  - 60
JO  - Guidelines in Practice
JF  - Guidelines in Practice
JA  - GUIDELINES PRACT
VL  - 13
IS  - 3
PB  - Medendium Group Publishing Ltd.
SN  - 1464-6420
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105199284&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105105734
T1  - QOF clinical indicators 2009/10: summary tables.
Y1  - 2010/09//2010 Sep
N1  - Accession Number: 105105734. Language: English. Entry Date: 20101105. Revision Date: 20150711. Publication Type: Journal Article; tables/charts. Journal Subset: Biomedical; Editorial Board Reviewed; Europe; Peer Reviewed; UK & Ireland. 
KW  - Primary Health Care
KW  - Quality Assurance
KW  - Quality of Health Care
KW  - Adrenergic Beta-Antagonists -- Therapeutic Use
KW  - Alcohol Drinking
KW  - Angina Pectoris -- Diagnosis
KW  - Angiotensin II Type I Receptor Blockers -- Therapeutic Use
KW  - Angiotensin-Converting Enzyme Inhibitors -- Therapeutic Use
KW  - Anticoagulants -- Therapeutic Use
KW  - Anticonvulsants -- Therapeutic Use
KW  - Aspirin -- Therapeutic Use
KW  - Asthma -- Diagnosis
KW  - Atrial Fibrillation -- Diagnosis
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Bipolar Disorder -- Diagnosis
KW  - Bipolar Disorder -- Drug Therapy
KW  - Blood Pressure
KW  - Blood Urea Nitrogen
KW  - Body Mass Index
KW  - Cardiovascular Diseases -- Prevention and Control
KW  - Case Management
KW  - Cerebral Ischemia, Transient
KW  - Cholesterol -- Blood
KW  - Contraception
KW  - Contraceptives, Oral
KW  - Contraceptives, Postcoital
KW  - Coronary Disease -- Prevention and Control
KW  - Counseling
KW  - Creatinine -- Blood
KW  - Dementia -- Diagnosis
KW  - Depression -- Diagnosis
KW  - Diabetes Mellitus -- Diagnosis
KW  - Diabetes Mellitus, Type 1 -- Diagnosis
KW  - Diabetes Mellitus, Type 2 -- Diagnosis
KW  - Diabetic Foot -- Prevention and Control
KW  - Diabetic Retinopathy -- Prevention and Control
KW  - Diet
KW  - Documentation
KW  - Dyspnea -- Diagnosis
KW  - Echocardiography
KW  - Electrocardiography
KW  - Epilepsy -- Diagnosis
KW  - Epilepsy -- Drug Therapy
KW  - Family Planning
KW  - Glomerular Filtration Rate
KW  - Health Screening -- Methods
KW  - Heart Failure -- Diagnosis
KW  - Heart Failure -- Ultrasonography
KW  - Hemoglobin A -- Blood
KW  - Hypertension -- Diagnosis
KW  - Hypertension -- Therapy
KW  - Hypothyroidism -- Diagnosis
KW  - Influenza Vaccine
KW  - Influenza -- Prevention and Control
KW  - Kidney Diseases
KW  - Learning Disorders -- Diagnosis
KW  - Life Style Changes
KW  - Lithium -- Therapeutic Use
KW  - Mental Disorders
KW  - Multidisciplinary Care Team
KW  - Myocardial Infarction -- Diagnosis
KW  - Myocardial Infarction -- Drug Therapy
KW  - Neoplasms -- Diagnosis
KW  - Obesity
KW  - Palliative Care
KW  - Physical Activity
KW  - Proteinuria
KW  - Psychotic Disorders -- Diagnosis
KW  - Pulmonary Disease, Chronic Obstructive
KW  - Pulmonary Disease, Chronic Obstructive -- Diagnosis
KW  - Referral and Consultation
KW  - Risk Assessment
KW  - Schizophrenia -- Diagnosis
KW  - Severity of Illness
KW  - Smoking Cessation
KW  - Smoking -- Diagnosis
KW  - Smoking -- Prevention and Control
KW  - Spirometry
KW  - Stroke
KW  - Thyroid Function Tests
KW  - Thyrotropin -- Blood
KW  - Transdermal Patches, Drugs
KW  - Ventricular Dysfunction, Left -- Complications
SP  - 69
EP  - 75
JO  - Guidelines in Practice
JF  - Guidelines in Practice
JA  - GUIDELINES PRACT
VL  - 13
IS  - 9
PB  - Medendium Group Publishing Ltd.
SN  - 1464-6420
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105105734&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105026525
T1  - Radiofrequency transseptal catheter electrode fracture.
AU  - Shah AJ
AU  - Janes R
AU  - Holliday J
AU  - Thakur R
Y1  - 2010/06//
N1  - Accession Number: 105026525. Language: English. Entry Date: 20100730. Revision Date: 20150711. Publication Type: Journal Article; case study; diagnostic images; pictorial. Journal Subset: Allied Health; Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7803944. 
KW  - Catheter Ablation -- Methods
KW  - Catheters -- Evaluation
KW  - Equipment Failure -- Evaluation
KW  - Aged
KW  - Atrial Fibrillation -- Therapy
KW  - Electrophysiology
KW  - Male
KW  - Surgery, Operative -- Methods
SP  - e57
EP  - 8
JO  - Pacing & Clinical Electrophysiology
JF  - Pacing & Clinical Electrophysiology
JA  - PACING CLIN ELECTROPHYSIOL
VL  - 33
IS  - 6
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Transseptal puncture is performed using a long needle advanced from the femoral approach. A radiofrequency catheter has been developed that delivers a short burst of radiofrequency energy and creates a micro puncture in the interatrial septum. We describe a case in which the distal radiofrequency electrode broke and became embedded in the interatrial septum. (PACE 2010; 33:e57-e58)
SN  - 0147-8389
AD  - Thoracic and Cardiovascular Institute, Sparrow Health System, Michigan State University, Lansing, Michigan
U2  - PMID: 20230468.
DO  - 10.1111/j.1540-8159.2010.02708.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107053246
T1  - Rate and rhythm control showed similar symptom improvement in atrial fibrillation...commentary on Hohnloser SH, Kuck KH, Lilienthal J, for the PIAF Investigators. Rhythm or rate control in atrial fibrillation -- Pharmacological Intervention in Atrial Fibrillation (PIAF): a randomised trial. LANCET 2000 Nov 25;356:1789-94
AU  - Belknap S
Y1  - 2001/07/03/
N1  - Accession Number: 107053246. Language: English. Entry Date: 20010921. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9104824. 
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Amiodarone -- Therapeutic Use
KW  - Diltiazem -- Therapeutic Use
KW  - Heart Rate -- Drug Effects
KW  - Clinical Trials
KW  - Prospective Studies
KW  - Cardioversion
KW  - Diltiazem -- Administration and Dosage
KW  - Amiodarone -- Administration and Dosage
KW  - Treatment Outcomes
KW  - Exercise Tolerance
KW  - Walking
KW  - Quality of Life
KW  - P-Value
KW  - Male
KW  - Female
KW  - Adult
KW  - Middle Age
KW  - Aged
KW  - Germany
SP  - 14
EP  - 14
JO  - ACP Journal Club
JF  - ACP Journal Club
JA  - ACP J CLUB
VL  - 135
IS  - 1
CY  - Philadelphia, Pennsylvania
PB  - American College of Physicians
SN  - 1056-8751
AD  - University of Illinois College of Medicine, at Peoria, Peoria, Illinois
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106277136
T1  - Rate control in atrial fibrillation: looking beyond the average heart rate.
AU  - Ahmad K
AU  - Dorian P
Y1  - 2006/03//
N1  - Accession Number: 106277136. Language: English. Entry Date: 20070504. Revision Date: 20150711. Publication Type: Journal Article; review. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 8608087. 
KW  - Antiarrhythmia Agents -- Therapeutic Use
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Electrocardiography
KW  - Heart Rate -- Drug Effects
KW  - Antiarrhythmia Agents -- Adverse Effects
KW  - Atrial Fibrillation -- Physiopathology
KW  - Atrial Fibrillation -- Psychosocial Factors
KW  - Cardiovascular System Physiology -- Drug Effects
KW  - Cardiovascular System Physiology
KW  - Clinical Trials
KW  - Comparative Studies
KW  - Exercise Physiology
KW  - Exercise -- Psychosocial Factors
KW  - Heart Failure -- Drug Therapy
KW  - Heart Failure -- Physiopathology
KW  - Heart Failure -- Psychosocial Factors
KW  - Heart Rate -- Physiology
KW  - Quality of Life
KW  - Relaxation -- Physiology
KW  - Relaxation -- Psychosocial Factors
SP  - 88
EP  - 93
JO  - Current Opinion in Cardiology
JF  - Current Opinion in Cardiology
JA  - CURR OPIN CARDIOL
VL  - 21
IS  - 2
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - PURPOSE OF REVIEW: The aim of this article is to provide a perspective on rate control in atrial fibrillation which emphasizes patient wellbeing (exercise tolerance, symptoms, quality of life) over attempts to reduce resting or exercise heart rate to an arbitrary range. RECENT FINDINGS: Recent trials of rhythm versus rate control strategies of treatment in patients with atrial fibrillation suggest that rate control is a viable first line strategy in many patients. The adverse consequences of atrial fibrillation with rapid ventricular response are partly due to factors other than rate itself, such as irregularity of ventricular response, and variable changes in autonomic nervous system output. Digoxin, calcium channel blockers, and beta-blockers cause a similar reduction in resting heart rate. Beta blockers are the most potent at reducing exercise heart rate, followed by calcium channel blockers and digoxin. Exercise tolerance is occasionally improved by digoxin, sometimes improved by calcium channel blockers and not improved by (and sometimes decreased by) beta-blockers. Information about quality of life with different rate control regimens is sparse. SUMMARY: Rate control in atrial fibrillation provides important benefits to patients in terms of symptoms, quality of life and prevention of late consequences of uncontrolled rate (such as tachycardia induced cardiomyopathy). Restricting treatment objectives to achievement of a specific heart rate range on resting or exercise electrocardiogram may result in lack of patient benefit or worsened symptoms. Understanding the nuances of rate control when treating individual patients and interpreting existing evidence allows patients to experience the most benefit from this treatment strategy.
SN  - 0268-4705
AD  - Division of Cardiology, St Michael's Hospital and University of Toronto, Toronto, Ontario, Canada.
U2  - PMID: 16470141.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106035391
T1  - Rate responsive pacing using the evoked qt principle. a physiological alternative to atrial synchronous pacemakers.
AU  - Donaldson RM
AU  - Rickards AF
Y1  - 1983/09/15/
N1  - Accession Number: 106035391. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Allied Health; Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7803944. 
SP  - 1344
EP  - 1349
JO  - Pacing & Clinical Electrophysiology
JF  - Pacing & Clinical Electrophysiology
JA  - PACING CLIN ELECTROPHYSIOL
VL  - 6
IS  - 5P2
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - We have evaluated clinically a rate-responsive pacemaker which uses the evoked QT principle as indicator of physiological demand. This pacemaker is microprocessor-based and fully programmable non invasively through radio frequency coupling to an external microcomputer. To date this system has been implanted in 15 patients. With this QT sensing pacemaker the rate response to exercise was smooth and progressive, and gradually returned to the basic paced rate after termination of activity. Physiologic rate responsive pacing resulted in significant improvement in exercise tolerance and a 40% increase in cardiac output when compared to fixed-rate pacing in 8 patients. This initial experience confirms the possibility of obtaining a physiological response to exercise using a pacing system dependent only on a nonpolar electrode which is independent of the problems of atrial activity and sensing. Rate responsive pacing might prove to be a useful alternative to atrial synchronous systems, and particularly advantageous in those patients whose senatorial function is abnormal or who suffer from atrial arrhythmias.
SN  - 0147-8389
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106035391&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109218587
T1  - Relation of Physical Activity and Incident Atrial Fibrillation (from the Multi-Ethnic Study of Atherosclerosis).
AU  - Bapat, Aneesh
AU  - Yiyi Zhang
AU  - Post, Wendy S.
AU  - Guallar, Eliseo
AU  - Soliman, Elsayed Z.
AU  - Heckbert, Susan R.
AU  - Lima, Joao
AU  - Bertoni, Alain G.
AU  - Alonso, Alvaro
AU  - Nazarian, Saman
Y1  - 2015/09/15/
N1  - Accession Number: 109218587. Language: English. Entry Date: 20151014. Revision Date: 20151014. Publication Type: journal article; research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0207277. 
KW  - Physical Activity -- Adverse Effects
KW  - Atrial Fibrillation -- Risk Factors
KW  - Secondary Analysis
KW  - Human
KW  - Female
KW  - Male
KW  - Cox Proportional Hazards Model
KW  - Confidence Intervals
KW  - Odds Ratio
KW  - P-Value
KW  - Descriptive Statistics
KW  - Association (Research)
KW  - Models, Statistical
KW  - Socioeconomic Factors
KW  - Cardiovascular Risk Factors
KW  - Causal Modeling
KW  - Exercise Intensity
SP  - 883
EP  - 888
JO  - American Journal of Cardiology
JF  - American Journal of Cardiology
JA  - AM J CARDIOL
VL  - 116
IS  - 6
CY  - Philadelphia, Pennsylvania
PB  - Elsevier Inc.
AB  - Previous studies have raised the question of whether an association exists between physical activity and atrial fibrillation (AF). We used the Multi-Ethnic Study of Atherosclerosis (MESA) database to examine the association between physical activity and AF in a diverse population without clinically recognized cardiovascular disease (CVD). MESA participants (n = 5,793) with complete baseline physical activity and covariate data were included. Cox proportional hazards models were used to calculate hazard ratios (HRs) for incident AF by levels of total intentional exercise and vigorous physical activity, independently and in combination. Multivariate models were adjusted for demographics and CVD risk factors. During a mean follow-up of 7.7 ± 1.9 years, 199 AF cases occurred. In the overall MESA population, neither vigorous physical activity nor total intentional exercise was independently associated with incident AF after adjusting for covariates. However, within the group that reported any vigorous physical activity, there was a statistically significant inverse association between total intentional exercise (modeled as a continuous variable) and incident AF. In those who reported any vigorous physical activity, the top tertile of total intentional exercise was associated with a significantly lower risk of incident AF compared with the group with no total intentional exercise in the fully adjusted model (HR 0.46, 95% confidence interval 0.22 to 0.98). In conclusion, neither total intentional exercise nor vigorous physical activity alone was associated with incident AF, but greater total intentional exercise was associated with a lower risk of incident AF in those who participated in any vigorous physical activity. As importantly, no subgroup of participants demonstrated an increased risk of incident AF with greater physical activity. The results re-emphasize the beneficial role of physical activity for cardiovascular health.
SN  - 0002-9149
AD  - Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
AD  - Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
AD  - Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland
AD  - Epidemiological Cardiology Research Center (EPICARE), Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, North Carolina
AD  - Department of Internal Medicine, Cardiology Section, Wake Forest School of Medicine, Winston-Salem, North Carolina
AD  - Department of Epidemiology, University of Washington, Seattle, Washington
AD  - Maya Angelou Center for Health Equity, Wake Forest University, Winston-Salem, North Carolina
AD  - Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, Minnesota
DO  - 10.1016/j.amjcard.2015.06.013
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109218587&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109622046
T1  - Relationship between Mediterranean diet and time in therapeutic range in atrial fibrillation patients taking vitamin K antagonists.
AU  - Pignatelli, Pasquale
AU  - Pastori, Daniele
AU  - Vicario, Tommasa
AU  - Bucci, Tommaso
AU  - Del Ben, Maria
AU  - Russo, Roberta
AU  - Tanzilli, Alessandra
AU  - Nardoni, Maria Lavinia
AU  - Bartimoccia, Simona
AU  - Nocella, Cristina
AU  - Ferro, Domenico
AU  - Saliola, Mirella
AU  - Cangemi, Roberto
AU  - Lip, Gregory Y H
AU  - Violi, Francesco
Y1  - 2015/08//
N1  - Accession Number: 109622046. Language: English. Entry Date: 20150923. Revision Date: 20160801. Publication Type: Journal Article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 100883649. 
SP  - 1223
EP  - 1228
JO  - EP: Europace
JF  - EP: Europace
JA  - EUROPACE
VL  - 17
IS  - 8
PB  - Oxford University Press / USA
SN  - 1099-5129
U2  - PMID: 25995397.
DO  - europace/euv127
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109622046&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 110466936
T1  - Relationship between Mediterranean diet and time in therapeutic range in atrial fibrillation patients taking vitamin K antagonists.
AU  - Pignatelli, Pasquale
AU  - Pastori, Daniele
AU  - Vicario, Tommasa
AU  - Bucci, Tommaso
AU  - Del Ben, Maria
AU  - Russo, Roberta
AU  - Tanzilli, Alessandra
AU  - Nardoni, Maria Lavinia
AU  - Bartimoccia, Simona
AU  - Nocella, Cristina
AU  - Ferro, Domenico
AU  - Saliola, Mirella
AU  - Cangemi, Roberto
AU  - Lip, Gregory Y H
AU  - Violi, Francesco
Y1  - 2015/08//
N1  - Accession Number: 110466936. Language: English. Entry Date: 20150923. Revision Date: 20160801. Publication Type: journal article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Instrumentation: Ferrans and Powers Quality of Life Index; Arthritis Impact Measurement Scale (AIMS) (Meenan). NLM UID: 100883649. 
KW  - Anticoagulants -- Administration and Dosage
KW  - Mediterranean Diet -- Statistics and Numerical Data
KW  - Vitamin K -- Antagonists and Inhibitors
KW  - Thromboembolism -- Prevention and Control
KW  - Atrial Fibrillation -- Therapy
KW  - Atrial Fibrillation -- Mortality
KW  - Aged
KW  - Comorbidity
KW  - Thromboembolism -- Mortality
KW  - Treatment Outcomes
KW  - Female
KW  - Risk Factors
KW  - Survival
KW  - Italy
KW  - Prevalence
KW  - Male
KW  - Arthritis Impact Measurement Scales
KW  - Ferrans and Powers Quality of Life Index
SP  - 1223
EP  - 1228
JO  - EP: Europace
JF  - EP: Europace
JA  - EUROPACE
VL  - 17
IS  - 8
PB  - Oxford University Press / USA
AB  - Aims: It is unclear if atrial fibrillation (AF) patients treated with oral vitamin K antagonists (VKAs) must follow a specific diet to avoid interference with anticoagulation. The aim of this study was to assess if Mediterranean diet (Med-Diet) may affect quality of anticoagulation, as expressed by the time in therapeutic range (TTR). Methods and Results: A prospective observational study including 553 non-valvular AF patients. Time in therapeutic range was calculated for all patients treated with VKAs, and adherence to Med-Diet was evaluated with a validated nine-item dietary questionnaire. Cardiovascular events (CVEs), such as cardiovascular death and fatal/non-fatal stroke or myocardial infarction, and bleedings were recorded. The median follow-up was 31.6 months. The median number of international normalized ratios for each patient was 63.0 (35.0-98.0) and 38 730 blood samples were analysed. In the whole cohort, the mean TTR was 65.5 ± 17.8%. The mean Med-Diet score was 5.19 ± 1.6, with frequent use of olive oil (90.1%), fruits (88.4%), and vegetables (69.3%) and low meat intake (71.2%). There were no differences among tertiles of Med-Diet score regarding TTR. A multivariable linear regression analysis showed that diabetes (β: -0.105, P = 0.015) and the use of angiotensin converting enzyme inhibitor/angiotensin receptor blockers (β: 0.153, P < 0.001) were associated with TTR. Compared with those without, AF patients with a CVE had significantly lower TTR (65.9 ± 17.9 vs. 59.6 ± 15.9, P = 0.029) and Med-Diet score (5.2 ± 1.5 vs. 4.4 ± 1.9, P = 0.004). A reduction of CVE was observed for each point of the Med-Diet score (hazard ratio 0.790, P = 0.017). Conclusion: In our cohort of AF patients, Med-Diet is not associated with changes in TTR, and thus can be recommended for AF patients who are taking VKAs.
SN  - 1099-5129
AD  - Center of Atherothrombosis, I Medical Clinic, Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Umberto I Policlinic of Rome, I Clinica Medica, Viale del Policlinico 155, Rome 00161, Italy
AD  - University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, UK
U2  - PMID: 25995397.
DO  - 10.1093/europace/euv127
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=110466936&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105763706
T1  - Research and development round-up: April 2008.
AU  - O'Connell N
Y1  - 2008/05//
N1  - Accession Number: 105763706. Language: English. Entry Date: 20080711. Revision Date: 20150711. Publication Type: Journal Article; abstract; diagnostic images. Journal Subset: Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 101175794. 
KW  - Alendronate -- Adverse Effects
KW  - Alzheimer's Disease -- Risk Factors
KW  - Angina Pectoris
KW  - Atrial Fibrillation -- Risk Factors
KW  - Bipolar Disorder -- Diet Therapy
KW  - Blood Substitutes -- Adverse Effects
KW  - Bone Resorption
KW  - Carboplatin -- Administration and Dosage
KW  - Coronary Arteriosclerosis -- Mortality
KW  - Drug Therapy, Combination
KW  - Drugs, Investigational
KW  - Fatty Acids, Omega-3
KW  - Female
KW  - Fluoxetine -- Therapeutic Use
KW  - Food Intake -- In Pregnancy
KW  - Heart Diseases -- Diagnosis
KW  - Hormone Replacement Therapy
KW  - Hypertension -- Drug Therapy
KW  - Lung Neoplasms -- Drug Therapy
KW  - Menopause
KW  - Migraine -- Complications
KW  - Multiple Sclerosis -- Drug Therapy
KW  - Myocardial Infarction -- Risk Factors
KW  - Osteoarthritis -- Drug Therapy
KW  - Paclitaxel -- Administration and Dosage
KW  - Phenytoin -- Adverse Effects
KW  - Plants, Medicinal
KW  - Pregnancy
KW  - Psoriasis -- Drug Therapy
KW  - Pyridines -- Administration and Dosage
KW  - Sensory Defensiveness
KW  - Sex Determination
KW  - Sex Factors
KW  - Statins -- Therapeutic Use
KW  - Stroke -- Prevention and Control
KW  - Thyrotropin -- Blood
SP  - 220
EP  - 226
JO  - Nurse Prescribing
JF  - Nurse Prescribing
JA  - NURSE PRESCRIBING
VL  - 6
IS  - 5
PB  - MA Healthcare Limited
SN  - 1479-9189
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105763706&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104596848
T1  - Research and development roundup: October 2011.
Y1  - 2011/10//
N1  - Accession Number: 104596848. Language: English. Entry Date: 20120106. Revision Date: 20150818. Publication Type: Journal Article; pictorial. Journal Subset: Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 101175794. 
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Blood Coagulation Factors -- Antagonists and Inhibitors
KW  - Cacao -- Therapeutic Use
KW  - Cluster Headache -- Drug Therapy
KW  - Food Intake
KW  - Injection Sites
KW  - Obesity -- Therapy
KW  - Primary Health Care
KW  - Referral and Consultation
KW  - Steroids -- Administration and Dosage
KW  - Warfarin
KW  - Weight Reduction Programs
SP  - 516
EP  - 517
JO  - Nurse Prescribing
JF  - Nurse Prescribing
JA  - NURSE PRESCRIBING
VL  - 9
IS  - 10
PB  - MA Healthcare Limited
SN  - 1479-9189
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104596848&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104515095
T1  - RESEARCH NEWS.
AU  - Tonks, Alison
Y1  - 2012/01/21/
N1  - Accession Number: 104515095. Language: English. Entry Date: 20120208. Revision Date: 20150711. Publication Type: Journal Article; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. NLM UID: 101090866. 
KW  - Cerebral Ischemia, Transient -- Etiology
KW  - Atrial Fibrillation
KW  - Fertilization in Vitro
KW  - Pregnancy
KW  - Female
KW  - Embryo Transfer
KW  - Obesity -- Epidemiology
KW  - United States
KW  - Myocardial Infarction -- Epidemiology
KW  - Running -- Evaluation
KW  - Infant, Newborn
KW  - Child, Preschool
KW  - Caffeine -- Therapeutic Use
KW  - Apnea -- Drug Therapy
KW  - Functional Status
KW  - Venous Thromboembolism -- Epidemiology
KW  - Arthroplasty, Replacement
KW  - Memantine -- Administration and Dosage
KW  - Down Syndrome -- Epidemiology
KW  - Cognition -- Drug Effects
SP  - 14
EP  - 15
JO  - BMJ: British Medical Journal (Overseas & Retired Doctors Edition)
JF  - BMJ: British Medical Journal (Overseas & Retired Doctors Edition)
JA  - BMJ BR MED J (OVERSEAS & RETIRED DOCTORS ED)
VL  - 344
IS  - 7840
PB  - BMJ Publishing Group
SN  - 1759-2151
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104515095&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104181027
T1  - Research Roundup.
Y1  - 2013/05//
N1  - Accession Number: 104181027. Language: English. Entry Date: 20130614. Revision Date: 20150711. Publication Type: Journal Article; abstract. Journal Subset: Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. 
KW  - Coronary Arteriosclerosis
KW  - Vegetarianism
KW  - Mediterranean Diet
KW  - Atrial Fibrillation
KW  - Cardiovascular Nursing
KW  - Rehabilitation, Cardiac
SP  - 220
EP  - 221
JO  - British Journal of Cardiac Nursing
JF  - British Journal of Cardiac Nursing
JA  - BR J CARD NURS
VL  - 8
IS  - 5
PB  - MA Healthcare Limited
SN  - 1749-6403
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104181027&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104227792
T1  - Research Roundup.
AU  - Linden, Belinda
Y1  - 2013/09//
N1  - Accession Number: 104227792. Language: English. Entry Date: 20130918. Revision Date: 20150711. Publication Type: Journal Article; abstract. Journal Subset: Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. 
KW  - Cardiovascular Diseases
KW  - Eggs
KW  - Resveratrol
KW  - Exercise
KW  - Aortic Valve Stenosis
KW  - Aged
KW  - Drug Therapy
KW  - Atrial Fibrillation
KW  - Anticoagulants
SP  - 423
EP  - 425
JO  - British Journal of Cardiac Nursing
JF  - British Journal of Cardiac Nursing
JA  - BR J CARD NURS
VL  - 8
IS  - 9
PB  - MA Healthcare Limited
SN  - 1749-6403
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104227792&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103914893
T1  - RESEARCH ROUNDUP.
AU  - Linden, Belinda
Y1  - 2014/11//
N1  - Accession Number: 103914893. Language: English. Entry Date: 20141118. Revision Date: 20150710. Publication Type: Journal Article. Journal Subset: Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. 
KW  - Cardiovascular Risk Factors
KW  - Diet
KW  - Life Style
KW  - Weight Control
KW  - Cardiovascular Diseases -- Familial and Genetic
KW  - Thrombosis
KW  - Stents
KW  - Heart Arrest
KW  - Atrial Fibrillation
SP  - 530
EP  - 531
JO  - British Journal of Cardiac Nursing
JF  - British Journal of Cardiac Nursing
JA  - BR J CARD NURS
VL  - 9
IS  - 11
PB  - MA Healthcare Limited
SN  - 1749-6403
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103914893&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

ID  - 110258505
T1  - Research Roundup.
AU  - Cowan, Helen
Y1  - 2015/10//
N1  - Accession Number: 110258505. Language: English. Entry Date: 20151016. Revision Date: 20151016. Publication Type: Abstract. Journal Subset: Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. 
KW  - Atrial Fibrillation -- Therapy
KW  - Stroke -- Risk Factors
KW  - Prevalence
KW  - Obesity
KW  - Atrial Fibrillation -- Risk Factors
KW  - Exercise
KW  - Weight Loss
KW  - Digoxin
KW  - Statins
KW  - Dementia
SP  - 476
EP  - 477
JO  - British Journal of Cardiac Nursing
JF  - British Journal of Cardiac Nursing
JA  - BR J CARD NURS
VL  - 10
IS  - 10
PB  - MA Healthcare Limited
SN  - 1749-6403
AD  - Elderly Care Nurse and Freelance Writer, Oxford
DO  - 10.12968/bjca.2015.10.10.476
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=110258505&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103837892
T1  - RESEARCH WE’RE WATCHING. Extra-virgin olive oil may lower afib risk.
Y1  - 2014/08//
N1  - Accession Number: 103837892. Language: English. Entry Date: 20140728. Revision Date: 20150710. Publication Type: Journal Article; brief item; pictorial. Journal Subset: Biomedical; USA. NLM UID: 9425723. 
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Mediterranean Diet
KW  - Olive Oil
KW  - Atrial Fibrillation -- Risk Factors
KW  - Nuts
SP  - 8
EP  - 8
JO  - Harvard Heart Letter
JF  - Harvard Heart Letter
JA  - HARV HEART LETT
VL  - 24
IS  - 12
CY  - Stamford, Connecticut
PB  - Harvard Health Publications
SN  - 1051-5313
U2  - PMID: 25230424.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103837892&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109544973
T1  - RESEARCH WE'RE WATCHING.
Y1  - 2015/10//
N1  - Accession Number: 109544973. Language: English. Entry Date: 20150922. Revision Date: 20151007. Publication Type: Article. Journal Subset: Biomedical; USA. NLM UID: 9425723. 
KW  - Passive Smoking
KW  - Stroke -- Risk Factors
KW  - Heart Diseases -- Drug Therapy
KW  - Aspirin -- Administration and Dosage
KW  - Myocardial Infarction -- Prevention and Control
KW  - Physical Fitness
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Exercise
SP  - 8
EP  - 8
JO  - Harvard Heart Letter
JF  - Harvard Heart Letter
JA  - HARV HEART LETT
VL  - 26
IS  - 2
CY  - Stamford, Connecticut
PB  - Harvard Health Publications
SN  - 1051-5313
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109544973&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109820790
T1  - RESEARCH WE'RE WATCHING.
Y1  - 2015/08//
N1  - Accession Number: 109820790. Language: English. Entry Date: 20150729. Revision Date: 20150923. Publication Type: Journal Article; abstract; pictorial. Journal Subset: Consumer Health; Peer Reviewed; USA. Special Interest: Consumer Health; Gerontologic Care; Women's Health. NLM UID: 9423147. 
KW  - Diphosphonates -- Therapeutic Use
KW  - Osteoporosis -- Prevention and Control
KW  - Cost Benefit Analysis
KW  - Estrogens
KW  - Depression
KW  - Selective Estrogen Receptor Modulators -- Therapeutic Use
KW  - Exercise
KW  - Diet
KW  - Atrial Fibrillation -- Prevention and Control
SP  - 8
EP  - 8
JO  - Harvard Women's Health Watch
JF  - Harvard Women's Health Watch
JA  - HARV WOMENS HEALTH WATCH
VL  - 22
IS  - 12
CY  - Stamford, Connecticut
PB  - Harvard Health Publications
SN  - 1070-910X
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109820790&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109646794
T1  - Response to Letter Regarding Article, 'Extravirgin Olive Oil Consumption Reduces Risk of Atrial Fibrillation: The PREDIMED (Prevención con Dieta Mediterránea) Trial'.
AU  - Martínez-González, Miguel A
AU  - Toledo, Estefanía
AU  - Arós, Fernando
AU  - Fiol, Miquel
AU  - Corella, Dolores
AU  - Salas-Salvadó, Jordi
AU  - Ros, Emilio
AU  - Covas, Maria I
AU  - Fernández-Crehuet, Joaquín
AU  - Lapetra, José
AU  - Muñoz, Miguel A
AU  - Fitó, Monserrat
AU  - Serra-Majem, Luis
AU  - Pintó, Xavier
AU  - Lamuela-Raventós, Rosa M
AU  - Sorlí, Jose V
AU  - Babio, Nancy
AU  - Buil-Cosiales, Pilar
AU  - Ruiz-Gutierrez, Valentina
AU  - Estruch, Ramón
Y1  - 2015/09/08/
N1  - Accession Number: 109646794. Language: English. Entry Date: 20150923. Revision Date: 20150923. Publication Type: Journal Article. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0147763. 
SP  - e140
EP  - 2
JO  - Circulation
JF  - Circulation
JA  - CIRCULATION
VL  - 132
IS  - 10
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
SN  - 0009-7322
U2  - PMID: 26354789.
DO  - 10.1161/CIRCULATIONAHA.114.013272
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105603308
T1  - Risk factor management to prevent first stroke.
AU  - Rundek T
AU  - Sacco RL
Y1  - 2008/11//2008 Nov
N1  - Accession Number: 105603308. Language: English. Entry Date: 20090403. Revision Date: 20150711. Publication Type: Journal Article; review; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 8219232. 
KW  - Stroke -- Prevention and Control
KW  - Stroke -- Risk Factors
KW  - Aspirin -- Administration and Dosage
KW  - Atrial Fibrillation -- Therapy
KW  - Diabetes Mellitus -- Prevention and Control
KW  - Hyperlipidemia -- Prevention and Control
KW  - Hypertension -- Prevention and Control
KW  - Life Style, Sedentary
KW  - Neurology
KW  - Smoking -- Complications
SP  - 1007
EP  - 1045
JO  - Neurologic Clinics
JF  - Neurologic Clinics
JA  - NEUROL CLIN
VL  - 26
IS  - 4
CY  - Philadelphia, Pennsylvania
PB  - W B Saunders
AB  - This article provides an overview on the management of risk factors to prevent primary strokes, the gaps in successful management, and future directions for the research and management of stroke risk factors. The major focus is given to the management of modifiable risk factors for stroke, including hypertension, diabetes, dyslipidemia, atrial fibrillation and other cardiac conditions, carotid artery stenosis, smoking, poor diet, physical inactivity, and obesity. A brief discussion on the management of potentially modifiable risk factors, such as alcohol and drug abuse, sleep apnea, and hyperhomocysteinemia, is included, as is the use of antiplatelet therapy in primary stroke prevention. Finally, prognostic scores to assess an individual risk for a first stroke are reviewed. Copyright © 2009 by Elsevier Inc.
SN  - 0733-8619
AD  - Department of Neurology, Miller School of Medicine, University of Miami, Miami, Florida, USA.
U2  - PMID: 19026901.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106741976
T1  - Risks for atrial fibrillation and congestive heart failure in patients > or = to 65 years of age with abnormal left ventricular diastolic relaxation.
AU  - Tsang TSM
AU  - Barnes ME
AU  - Gersh BJ
AU  - Bailey KR
AU  - Seward JB
Y1  - 2004/01//
N1  - Accession Number: 106741976. Language: English. Entry Date: 20040604. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Grant Information: American Heart Association, Dallas, Texas, and the American Society of Echocardiography. NLM UID: 0207277. 
KW  - Atrial Fibrillation -- Risk Factors
KW  - Heart Failure -- Risk Factors
KW  - Ventricular Dysfunction, Left -- Complications -- In Old Age
KW  - Age Factors
KW  - Aged
KW  - Confidence Intervals
KW  - Cox Proportional Hazards Model
KW  - Descriptive Statistics
KW  - Diabetes Mellitus -- Complications
KW  - Female
KW  - Funding Source
KW  - Heart Atrium, Left -- Pathology
KW  - Heart Ventricle, Left -- Pathology
KW  - Kaplan-Meier Estimator
KW  - Male
KW  - Myocardial Infarction -- Complications
KW  - Prospective Studies
KW  - Retrospective Design
KW  - Two-Tailed Test
KW  - Human
SP  - 54
EP  - 58
JO  - American Journal of Cardiology
JF  - American Journal of Cardiology
JA  - AM J CARDIOL
VL  - 93
IS  - 1
CY  - Philadelphia, Pennsylvania
PB  - Elsevier Inc.
SN  - 0002-9149
AD  - Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905; tsang.teresa@mayo.edu
U2  - PMID: 14697466.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104850942
T1  - Safeguarding your brain.
Y1  - 2011/04//
N1  - Accession Number: 104850942. Language: English. Entry Date: 20110406. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Consumer Health; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Consumer Health. NLM UID: 9425420. 
KW  - Stroke -- Prevention and Control
KW  - Health Behavior
KW  - Stroke -- Risk Factors
KW  - Practice Guidelines
KW  - Hypertension -- Therapy
KW  - Blood Pressure
KW  - Life Style Changes
KW  - Hyperlipidemia -- Therapy
KW  - Antihypertensive Agents -- Therapeutic Use
KW  - Cardiovascular Risk Factors -- Prevention and Control
KW  - Lipoproteins, LDL Cholesterol -- Analysis
KW  - Glycemic Control
KW  - Blood Glucose -- Analysis
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Anticoagulants -- Therapeutic Use
KW  - Carotid Stenosis -- Surgery
KW  - Diet
KW  - Exercise
KW  - Weight Control
KW  - Smoking Cessation
SP  - 1
EP  - 5
JO  - Consumer Reports on Health
JF  - Consumer Reports on Health
JA  - CONSUM REP HEALTH
VL  - 23
IS  - 4
CY  - Yonkers, New York
PB  - Consumers Union
SN  - 1044-3193
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 111511310
T1  - Secondary prevention of stroke.
AU  - White, Carole L.
Y1  - 2015/12//
N1  - Accession Number: 111511310. Language: English. Entry Date: 20160113. Revision Date: 20160113. Publication Type: Article. Journal Subset: Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 101291565. 
KW  - Stroke -- Prevention and Control
KW  - Recurrence -- Prevention and Control
KW  - Education, Continuing
KW  - Cerebral Ischemia, Transient -- Symptoms
KW  - Stroke -- Symptoms
KW  - Stroke -- Risk Factors
KW  - Hypertension -- Drug Therapy
KW  - Hyperlipidemia -- Drug Therapy
KW  - Cerebral Ischemia -- Symptoms
KW  - Practice Guidelines
KW  - Cerebral Ischemia, Transient -- Prevention and Control
KW  - Cerebral Ischemia -- Prevention and Control
KW  - Diabetes Mellitus -- Drug Therapy
KW  - Physical Activity
KW  - Smoking Cessation
KW  - Obesity -- Prevention and Control
KW  - Diet
KW  - Nutrition
KW  - Alcohol Drinking -- Prevention and Control
KW  - Stroke -- Drug Therapy
KW  - Platelet Aggregation Inhibitors -- Therapeutic Use
KW  - Anticoagulants -- Therapeutic Use
KW  - Atrial Fibrillation -- Complications
KW  - Life Style Changes
KW  - Health Promotion
KW  - Checklists
KW  - Self Care
KW  - Information Resources
KW  - World Wide Web
SP  - 17
EP  - 1
JO  - American Nurse Today
JF  - American Nurse Today
JA  - AM NURSE TODAY
VL  - 10
IS  - 12
CY  - Doylestown, Pennsylvania
PB  - HealthCom Media
SN  - 1930-5583
AD  - Associate professor in the School of Nursing, University of Texas Health Sciences Center, San Antonio
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109631987
T1  - Secondary stroke prevention: challenges and solutions.
AU  - Esenwa, Charles
AU  - Gutierrez, Jose
Y1  - 2015/01//
N1  - Accession Number: 109631987. Language: English. Entry Date: 20150923. Revision Date: 20160526. Publication Type: journal article; review. Journal Subset: Australia & New Zealand; Biomedical; Peer Reviewed. Grant Information: T32 NS007153/NS/NINDS NIH HHS/United States. NLM UID: 101273479. 
SP  - 437
EP  - 450
JO  - Vascular Health & Risk Management
JF  - Vascular Health & Risk Management
JA  - VASC HEALTH RISK MANAGE
VL  - 11
CY  - Auckland, <Blank>
PB  - Dove Medical Press Ltd
AB  - Stroke is the leading cause of disability in the USA and a major cause of mortality worldwide. One out of four strokes is recurrent. Secondary stroke prevention starts with deciphering the most likely stroke mechanism. In general, one of the main goals in stroke reduction is to control vascular risk factors such as hypertension, diabetes, dyslipidemia, and smoking cessation. Changes in lifestyle like a healthy diet and aerobic exercise are also recommended strategies. In the case of cardioembolism due to atrial fibrillation, mechanical valves, or cardiac thrombus, anticoagulation is the mainstay of therapy. The role of anticoagulation is less evident in the case of bioprosthetic valves, patent foramen ovale, and dilated cardiomyopathy with low ejection fraction. Strokes due to larger artery atherosclerosis account for approximately a third of all strokes. In the case of symptomatic extracranial carotid stenosis, surgical intervention as close as possible in time to the index event seems highly beneficial. In the case of intracranial large artery atherosclerosis, the best medical therapy consists of antiplatelets, high-dose statins, aggressive controls of vascular risk factors, and lifestyle modifications, with no role for intracranial arterial stenting or angioplasty. For patients with small artery occlusion (ie, lacunar stroke), the therapy is similar to that used in patients with intracranial large artery atherosclerosis. Despite the constant new evidence on how to best treat patients who have suffered a stroke, the risk of stroke recurrence remains unacceptably high, thus evidencing the need for novel therapies.
SN  - 1176-6344
U2  - PMID: 26300647.
DO  - 10.2147/VHRM.S63791
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106145285
T1  - Selective atrial vagal denervation guided by evoked vagal reflex to treat patients with paroxysmal atrial fibrillation.
AU  - Scanavacca M
AU  - Pisani CF
AU  - Hachul D
AU  - Lara S
AU  - Hardy C
AU  - Darrieux F
AU  - Trombetta I
AU  - Negrao CE
AU  - Sosa E
Y1  - 2006/08/29/2006 Aug 29
N1  - Accession Number: 106145285. Language: English. Entry Date: 20070831. Revision Date: 20150711. Publication Type: Journal Article; clinical trial; research. Commentary: Morady F. [Commentary on] Selective atrial vagal denervation guided by evoked vagal reflex to treat patients with paroxysmal atrial fibrillation. (ACC CARDIOSOURCE REV J) 2006 Nov; 15 (11): 2-2. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Evidence-Based Practice. NLM UID: 0147763. 
KW  - Atrial Fibrillation -- Therapy
KW  - Catheter Ablation -- Methods
KW  - Vagus Nerve -- Physiopathology
KW  - Adolescence
KW  - Adult
KW  - Aged
KW  - Amiodarone -- Therapeutic Use
KW  - Antiarrhythmia Agents -- Therapeutic Use
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Atrial Fibrillation -- Physiopathology
KW  - Denervation
KW  - Electrophysiology -- Methods
KW  - Heart Conduction System -- Physiology
KW  - Middle Age
KW  - Relaxation -- Physiology
KW  - Sleep -- Physiology
KW  - Treatment Outcomes
KW  - Human
SP  - 876
EP  - 885
JO  - Circulation
JF  - Circulation
JA  - CIRCULATION
VL  - 114
IS  - 9
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - BACKGROUND: The aim of this study was to evaluate whether selective radiofrequency (RF) catheter ablation of the atrial sites in which high-frequency stimulation induces vagal reflexes prevents paroxysmal atrial fibrillation (AF). METHODS AND RESULTS: Ten patients with episodes suggestive of vagal-induced paroxysmal AF and no heart disease were selected for percutaneous epicardial and endocardial mapping of the atria to search for sites in which high-frequency transcatheter stimulation (20 Hz,) induced vagal reflexes. A vagal response defined as AV block of > 2 seconds was elicited in 7 of 10 patients (70%) with an average of 5 +/- 2.4 (range, 2 to 9) sites per patient, and RF pulses (21.0 +/- 12.0 per patient) were applied at those sites to eliminate all evoked vagal reflexes. The 3 patients in whom evoked vagal reflexes were not obtained underwent circumferential pulmonary vein ablation with an average of 58.0 +/- 13.9 RF pulses per patient (P = 0.022). Autonomic evaluation was performed before and 48 hours and 3 months after the procedure and was consistent with vagal withdrawal in all patients. Two of the 7 patients who underwent denervation remained asymptomatic without the use of antiarrhythmic medication at a mean follow-up of 8.3 +/- 2.8 months (range, 5 to 15 months); 4 had frequent recurrences and were referred for circumferential pulmonary vein ablation; and 1 had few AF episodes without antiarrhythmic medication. The 3 patients without evoked vagal reflexes who underwent circumferential pulmonary vein ablation remained asymptomatic without antiarrhythmic medication. One patient had acute delayed gastric emptying after atrial vagal denervation. CONCLUSIONS: RF catheter ablation of selected atrial sites in which high-frequency stimulation induced vagal reflexes may prevent AF recurrences in selected patients with apparently vagal-induced paroxysmal AF.
SN  - 0009-7322
AD  - Unidade Clínica de Arritmia, Heart Institute, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar 44, CEP 05403-000, Sao Paulo/SP, Brazil. mauricio.scanavacca@incor.usp.br
U2  - PMID: 16923757.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106994045
T1  - Serum vitamin C concentration was inversely associated with subsequent 20-year incidence of stroke in a Japanese rural community: the Shibata study.
AU  - Yokoyama T
AU  - Date C
AU  - Kokubo Y
AU  - Yoshiike N
AU  - Matsumura Y
AU  - Tanaka H
Y1  - 2000/10//2000 Oct
N1  - Accession Number: 106994045. Language: English. Entry Date: 20010126. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Allied Health; Biomedical; Peer Reviewed; USA. Instrumentation: Semiquantitative Food Frequency Questionnaire (FFQ). Grant Information: No. 9A-3, from the Ministry of Health and Welfare, Japan; No. 3A-3, from the National Center of Neurology and Psychiatry, Japan; and No. 3C-2 from the National Cardiovascular Center, Japan. NLM UID: 0235266. 
KW  - Stroke -- Epidemiology
KW  - Ascorbic Acid -- Blood
KW  - Ascorbic Acid -- Administration and Dosage
KW  - Risk Factors
KW  - Blood Pressure
KW  - Epidemiological Research
KW  - Prospective Studies
KW  - Cholesterol -- Blood
KW  - Food Intake
KW  - Questionnaires
KW  - Cox Proportional Hazards Model
KW  - Pearson's Correlation Coefficient
KW  - Data Analysis Software
KW  - Analysis of Covariance
KW  - Fisher's Exact Test
KW  - Adult
KW  - Middle Age
KW  - Aged
KW  - Female
KW  - Male
KW  - Funding Source
KW  - Human
SP  - 2287
EP  - 2294
JO  - Stroke (00392499)
JF  - Stroke (00392499)
JA  - STROKE
VL  - 31
IS  - 10
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - Background and Purpose--Epidemiological evidence suggests that vitamin C may decrease the risk of stroke. The purpose of the present study was to examine the association of serum vitamin C concentration with the subsequent incidence of stroke.Methods--In a Japanese rural community, a cohort of 880 men and 1241 women aged 40 years and older who were initially free of stroke was examined in 1977 and followed until 1997. The baseline examination included a measurement of serum vitamin C concentration. The incidence of stroke was determined by annual follow-up examinations and registry.Results--During the 20-year observation period, 196 incident cases of all stroke, including 109 cerebral infarctions and 54 hemorrhagic strokes, were documented. Strong inverse associations were observed between serum vitamin C concentration and all stroke (sex- and age-adjusted hazard ratios were 0.93, 0.72, and 0.59, respectively, for the second, third, and fourth quartiles compared with the first quartile; P for trend=0.002), cerebral infarction (0.71, 0.59, and 0.51; P for trend=0.015), and hemorrhagic stroke (0.89, 0.75, and 0.45; P for trend=0.013). Additional adjustments for blood pressure, serum total cholesterol, body mass index, physical activity, smoking, alcohol drinking, antihypertensive medication, atrial fibrillation, and history of ischemic heart disease did not attenuate these associations markedly.Conclusions--Serum vitamin C concentration was inversely related to the subsequent incidence of stroke. This relationship was significant for both cerebral infarction and hemorrhagic stroke. Additional mechanistic hypotheses may be required to explain our findings.
SN  - 0039-2499
AD  - Dept of Epidemiology, Medical Research Institute, Tokyo Medical and Dental University, 2-3-10, Kanda-surugadai Chiyoda-ku, Tokyo, 101-0062 Japan; yoko.epi@mri.tmd.ac.jp
U2  - PMID: 11022052.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108251631
T1  - SHORT CUTS.
AU  - Fi¿ter, Kristina
Y1  - 2011/08/18/2011 Aug 18
N1  - Accession Number: 108251631. Language: English. Entry Date: 20110909. Revision Date: 20150712. Publication Type: Journal Article; pictorial; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. NLM UID: 101090866. 
KW  - Atrial Fibrillation -- Therapy
KW  - Warfarin -- Therapeutic Use
KW  - Anticoagulants -- Therapeutic Use
KW  - United Kingdom
KW  - Stroke -- Risk Factors
KW  - Pulmonary Embolism -- Risk Factors
KW  - Serial Publications
KW  - Male
KW  - Female
KW  - Smoking -- Complications
KW  - Heart Diseases -- Risk Factors
KW  - Exercise
KW  - Life Expectancy
KW  - Constipation -- Therapy
SP  - 392
EP  - 393
JO  - BMJ: British Medical Journal (Overseas & Retired Doctors Edition)
JF  - BMJ: British Medical Journal (Overseas & Retired Doctors Edition)
JA  - BMJ BR MED J (OVERSEAS & RETIRED DOCTORS ED)
VL  - 343
IS  - 7820
PB  - BMJ Publishing Group
SN  - 1759-2151
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105489574
T1  - Short cuts: all you need to read in the other general journals.
AU  - Tonks A
Y1  - 2009/03/07/
N1  - Accession Number: 105489574. Language: English. Entry Date: 20090515. Revision Date: 20150711. Publication Type: Journal Article; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. NLM UID: 101090866. 
KW  - Epilepsy -- Risk Factors
KW  - Head Injuries -- Complications
KW  - Atrial Fibrillation -- Therapy
KW  - Cardiovascular Diseases -- Prevention and Control
KW  - Ciprofloxacin -- Therapeutic Use
KW  - Depression -- Complications
KW  - Diabetes Mellitus -- Risk Factors
KW  - Dialysis
KW  - Diet, Reducing
KW  - Female
KW  - Hypertension -- Therapy
KW  - Macular Degeneration -- Prevention and Control
KW  - Neisseria Infections -- Diagnosis
KW  - United Kingdom
KW  - United States
KW  - Vitamins -- Therapeutic Use
SP  - 566
EP  - 567
JO  - BMJ: British Medical Journal (Overseas & Retired Doctors Edition)
JF  - BMJ: British Medical Journal (Overseas & Retired Doctors Edition)
JA  - BMJ BR MED J (OVERSEAS & RETIRED DOCTORS ED)
PB  - BMJ Publishing Group
SN  - 1759-2151
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106308354
T1  - Short-term and long-term effects of bisoprolol on chronic heart failure related to rheumatic heart disease and atrial fibrillation.
AU  - Shu M
AU  - Xi R
AU  - Zhang P
AU  - He G
AU  - Song Z
AU  - Chi L
AU  - Zhuang G
Y1  - 2005/07//2005 Jul
N1  - Accession Number: 106308354. Language: English. Entry Date: 20060728. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Grant Information: Departments of Cardiology and Ultrasound Diagnosis in Southwest Hospital. NLM UID: 9015516. 
KW  - Adrenergic Beta-Antagonists -- Therapeutic Use
KW  - Heart Failure -- Drug Therapy
KW  - Adrenergic Beta-Antagonists -- Administration and Dosage
KW  - Adrenergic Beta-Antagonists -- Adverse Effects
KW  - Adrenergic Beta-Antagonists -- Pharmacodynamics
KW  - Adult
KW  - Atrial Fibrillation -- Complications
KW  - Atrial Fibrillation -- Diagnosis
KW  - Atrial Fibrillation -- Physiopathology
KW  - Chi Square Test
KW  - Clinical Assessment Tools
KW  - Descriptive Statistics
KW  - Drug Therapy, Combination
KW  - Echocardiography
KW  - Exercise Test -- Methods
KW  - Female
KW  - Funding Source
KW  - Heart Failure -- Diagnosis
KW  - Heart Failure -- Etiology
KW  - Heart Failure -- Physiopathology
KW  - Heart Function Tests
KW  - Heart Rate -- Drug Effects
KW  - Length of Stay
KW  - Male
KW  - Random Assignment
KW  - Rheumatic Heart Disease -- Complications
KW  - Rheumatic Heart Disease -- Diagnosis
KW  - Rheumatic Heart Disease -- Physiopathology
KW  - Systole
KW  - T-Tests
KW  - Treatment Outcomes
KW  - Ventricular Ejection Fraction -- Drug Effects
KW  - Human
SP  - 400
EP  - 407
JO  - P&T: A Peer-Reviewed Journal for Managed Care & Formulary Management
JF  - P&T: A Peer-Reviewed Journal for Managed Care & Formulary Management
JA  - P&T
VL  - 30
IS  - 7
CY  - Yardley, Pennsylvania
PB  - MediMedia Managed Markets, an ICON Company
AB  - Objective: We investigated whether a selective beta, blocker, bisoprolol, improved chronic heart failure (HF) related to rheumatic heart disease (RHD) and atrial fibrillation (AF).Methods: We randomly assigned 88 chronic HF patients with RHD, a cardiothoracic ratio below 65%, and AF with a resting ventricular rate of 70 beats/minute or more for at least three months to either a treatment group or a control group. All patients received basic therapy: a diuretic, digoxin, an angiotensin-converting enzyme (ACE)-inhibitor/angiotensin receptor blocker (ARB), or nitrates, depending on their blood pressure level and the presence of valvular lesions. All patients also received warfarin. Patients in the treatment group received bisoprolol. We then compared the short-term and long-term clinical and hemodynamic variables between the two groups.Results:Basic Characteristics. Thirty-three treated patients (75.0%) and 34 control patients (77.3%) completed the study. The follow-up period for both groups of patients was similar. There were no significant differences in age, sex, disease du-ration, the use of diuretics and ACE-inhibitors or ARBs, left ventricular (LV) end-diastolic dimension, or left atrial (LA) diameter. The LV ejection fraction (LVEF) for all patients was found to be higher than 40% in the two groups. Only three patients had an LVEF below 45%. The average maximum bisoprolol dose was 6.52 +/- 2.7 mg/day in the treatment group; 54.5% of the patients tolerated at least 5 mg of bisoprolol once daily.Short-Term Results. The length of hospital stay was significantly shorter for the treated patients. At hospital discharge, these patients had a slower 24-hour average ventricular rate and were able to walking farther over a period of six minutes, compared with the control group.Long- Term Results. During the follow-up period, the combined endpoint of chronic HF-related and thromboembolismrelated death or hospitalization in the treated patients was significantly lower than that in the control patients. After six to 12 months, only the control patients had a higher 24-hour average ventricular rate, a worse New York Heart Association (NYHA) class, and a lower exercise capacity. In contrast, the treatment group showed improved NYHA class and exercise capacity as well as a lower 24-hour average ventricular rate, lower systolic blood pressure; and a significantly decreased LA diameter. However, no significant changes in the LVEF or LV end-diastolic dimension were noted in the two groups during follow-up.Summary: The data suggest that a selective beta[1], blocker might improve NYHA class and exercise tolerance for patients with chronic HF related to RHD and AE Furthermore, the advantage of these effects provided by this agent might be mediated by a reduction in ventricular rate and LA volume.
SN  - 1052-1372
AD  - Vice-Professor, Department of Cardiology, Southwest Hospital, The Third Military Medical University, Chongqing, China
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107126416
T1  - Some drugs provide better control of heart rate for patients with atrial fibrillation at both rest and exercise.
Y1  - 2000/05//2000 May
N1  - Accession Number: 107126416. Language: English. Entry Date: 20000801. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; USA. NLM UID: 9102229. 
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Calcium Channel Blockers -- Therapeutic Use
KW  - Adrenergic Beta-Antagonists -- Therapeutic Use
SP  - 4
EP  - 4
JO  - AHRQ Research Activities
JF  - AHRQ Research Activities
JA  - RES ACTIVITIES
IS  - 237
CY  - Rockville, Maryland
PB  - Agency for Healthcare Research & Quality
SN  - 1537-0224
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DP  - EBSCOhost
DB  - ccm
ER  - 

ID  - 32107384
T1  - Sophia.
Y1  - 2008/03//
N1  - Accession Number: 32107384. Language: English. Entry Date: 20080411. Revision Date: 20120622. Publication Type: Abstract. Journal Subset: Allied Health; Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. NLM UID: 100963089. 
SP  - 186
EP  - 186
JO  - Emergency Medicine Journal
JF  - Emergency Medicine Journal
JA  - EMERG MED J
VL  - 25
IS  - 3
PB  - BMJ Publishing Group
AB  - The article presents abstracts on emergency medicine-related topics which include the effectiveness of acupressure in the treatment of pain resulting from distal radial fractures, the use of intravenous magnesium in the treatment of acute onset atrial fibrillation, and the association between a positive focused assessment with sonography for trauma (FAST) scan performed in the emergency room and therapeutic laparotomy in blunt trauma patients who remained normotensive.
SN  - 1472-0205
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106312445
T1  - Spirituality: don't pray for me! Please!
AU  - Kalb C
Y1  - 2006/04/10/
N1  - Accession Number: 106312445. Language: English. Entry Date: 20060804. Revision Date: 20150711. Publication Type: Journal Article; brief item; pictorial. Journal Subset: Consumer Health; USA. NLM UID: 9877127. 
KW  - Coronary Artery Bypass
KW  - Prayer
KW  - Treatment Outcomes
KW  - Academic Medical Centers
KW  - Atrial Fibrillation
KW  - Clinical Research
KW  - Outcomes Research
SP  - 15
EP  - 15
JO  - Newsweek
JF  - Newsweek
JA  - NEWSWEEK
VL  - 147
IS  - 15
CY  - New York, New York
PB  - Newsweek LLC
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106312445&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104482463
T1  - Step by step towards a clinical pathway.
AU  - Zwaan, Esther
AU  - Umans, Victor
Y1  - 2012/03//
N1  - Accession Number: 104482463. Language: English. Entry Date: 20120727. Revision Date: 20150711. Publication Type: Journal Article; tables/charts. Journal Subset: Europe; Health Services Administration; Peer Reviewed; UK & Ireland. NLM UID: 101498814. 
KW  - Critical Path
KW  - Program Implementation -- Netherlands
KW  - Atrial Fibrillation -- Therapy
KW  - Electrochemical Techniques -- Utilization
KW  - Quality Improvement
KW  - Health Care Delivery, Integrated
KW  - Outpatients
KW  - Patient Admission
KW  - Organizational Efficiency
KW  - Patient Safety
KW  - Netherlands
KW  - Patient Satisfaction
KW  - Clinical Indicators
KW  - Multidisciplinary Care Team
SP  - 19
EP  - 24
JO  - International Journal of Care Pathways
JF  - International Journal of Care Pathways
JA  - INT J CARE PATHWAYS
VL  - 16
IS  - 1
PB  - Sage Publications, Ltd.
AB  - Clinical pathways attempt to increase efficiency by organizing the care delivery process into individual analysable steps. We evaluate a digital clinical pathway for electrocardioversion in atrial fibrillation with a nurse coordinator in the ongoing consecutive experience in clinical practice. This paper describes the implementation and effects of introducing a clinical pathway. The pathway was launched in January 2008. Up to January 2009, 450 all-comer elective patients have been treated using this integrated digital clinical pathway without exception. Treatment and outpatient check-up appointments are made immediately for all patients. The pathway reduced walk-through times significantly. A clinical pathway for cardioversion patients is safely and efficaciously introduced in a teaching hospital.
SN  - 2040-4026
AD  - Cardiology Department, Medical Center Alkmaar, Alkmaar, The Netherlands
DO  - 10.1258/jicp.2012.010031
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105051962
T1  - Stroke medicine for the geriatrician 2010.
AU  - Keir SL
AU  - Strachan K
Y1  - 2010/05//
N1  - Accession Number: 105051962. Language: English. Entry Date: 20100820. Revision Date: 20150711. Publication Type: Journal Article; diagnostic images; review; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Gerontologic Care. NLM UID: 9114340. 
KW  - Gerontologic Care
KW  - Stroke -- In Old Age
KW  - Aged
KW  - Anoxia -- Complications
KW  - Anticoagulants -- Therapeutic Use
KW  - Aspirin -- Therapeutic Use
KW  - Atrial Fibrillation -- Complications
KW  - Blood Pressure
KW  - Carotid Stenosis -- Complications
KW  - Deglutition Disorders -- Complications
KW  - Dehydration -- Complications
KW  - Fever -- Complications
KW  - Hospital Units
KW  - Hypercholesterolemia -- Drug Therapy
KW  - Hyperglycemia -- Complications
KW  - Hyperglycemia -- Drug Therapy
KW  - Hypertension -- Drug Therapy
KW  - Incidence
KW  - Insulin -- Therapeutic Use
KW  - Magnetic Resonance Imaging
KW  - Neurosurgery -- Methods
KW  - Nutrition
KW  - Pulmonary Embolism -- Risk Factors
KW  - Smoking Cessation
KW  - Stroke -- Diagnosis
KW  - Stroke -- Drug Therapy
KW  - Stroke -- Epidemiology
KW  - Stroke -- Mortality
KW  - Stroke -- Prevention and Control
KW  - Stroke -- Prognosis
KW  - Stroke -- Radiography
KW  - Stroke -- Risk Factors
KW  - Stroke -- Surgery
KW  - Stroke -- Therapy
KW  - Tissue Plasminogen Activator -- Therapeutic Use
KW  - Tomography, X-Ray Computed
KW  - Venous Thrombosis -- Prevention and Control
SP  - 92
EP  - 104
JO  - Reviews in Clinical Gerontology
JF  - Reviews in Clinical Gerontology
JA  - REV CLIN GERONTOL
VL  - 20
IS  - 2
PB  - Cambridge University Press
AB  - This review explores the recent advances in investigation and treatment of acute stroke, as well as its secondary prevention, with emphasis on the relevance of the evidence for the older population. Hyperacute reperfusion treatment is becoming increasingly embedded into the day-to-day management of stroke and trials are ongoing that will help determine its safety in the older patient. Managing all stroke patients in a stroke unit is known to improve outcome and recent work has helped to inform care decisions. Application of the robust data available on secondary prevention treatments may have to be weighed alongside the degree of frailty of the patient for whom treatment is being considered.
SN  - 0959-2598
AD  - Department of Medicine for the Elderly, Western General Hospital, Edinburgh EH4 2XU, UK; Sarah.kei@luht.scot.nhs.uk
DO  - 10.1017/S0959259810000122
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106364539
T1  - Stroke prevention and management in older adults.
AU  - Michael KM
AU  - Shaughnessy M
Y1  - 2006/09/02/Sep/Oct2006 Supplement 5
N1  - Accession Number: 106364539. Language: English. Entry Date: 20061124. Revision Date: 20150818. Publication Type: Journal Article. Supplement Title: Sep/Oct2006 Supplement 5. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Special Interest: Gerontologic Care. NLM UID: 8703516. 
KW  - Stroke -- Prevention and Control -- In Old Age
KW  - Stroke -- Risk Factors -- In Old Age
KW  - Aged
KW  - Aged, 80 and Over
KW  - Atrial Fibrillation
KW  - Carotid Stenosis
KW  - Diabetes Mellitus
KW  - Funding Source
KW  - Hyperlipidemia
KW  - Hypertension
KW  - Nursing Role
KW  - Stroke -- Drug Therapy
KW  - Stroke -- Rehabilitation
KW  - Stroke -- Symptoms
KW  - Tissue Plasminogen Activator
SP  - S21
EP  - 6
JO  - Journal of Cardiovascular Nursing
JF  - Journal of Cardiovascular Nursing
JA  - J CARDIOVASC NURS
VL  - 21
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - Stroke is the third leading cause of death and a foremost cause of serious, long-term disability in the United States. As cardiovascular and metabolic disease incidence rises with age, older people are more likely to experience strokes. Age is the single most important risk factor for stroke. For each successive 10 years after age 55, the stroke rate more than doubles in both men and women. However, stroke is not an inevitable consequence of aging. By identifying and modifying risk factors in older people, nurses can partner with other providers to reduce the incidence, morbidity, and mortality associated with stroke in older adults. Control of hypertension, resolution of dyslipidemia, management of diabetes mellitus, anticoagulation for atrial fibrillation, promotion of exercise and healthy diet, and cessation of cigarette smoking are of particular importance in older adults. Recognition of stroke symptoms, access to emergency evaluation and treatments, and participation in comprehensive rehabilitation may determine stroke outcomes in aging. This article presents stroke risk factors and primary and secondary prevention in the context of aging, with special considerations in the identification and management of acute stroke, recovery, and rehabilitation for older adults who survive stroke.
SN  - 0889-4655
AD  - Assistant Professor, University of Maryland School of Nursing, Claude D Pepper Older Americans Independence Center, Baltimore, MD
U2  - PMID: 16966926.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108076713
T1  - Study of Warfarin Patients Investigating Attitudes Toward Therapy Change (SWITCH Survey)
AU  - Attaya S
AU  - Bornstein T
AU  - Ronquillo N
AU  - Volgman R
AU  - Braun LT
AU  - Trohman R
AU  - Volgman A
Y1  - 2012/11//2012 Nov
N1  - Accession Number: 108076713. Language: English. Entry Date: 20130517. Revision Date: 20150712. Publication Type: Journal Article; research. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9441347. 
KW  - Anticoagulants -- Therapeutic Use
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Patient Attitudes
KW  - Warfarin -- Therapeutic Use
KW  - Administration, Oral
KW  - Adult
KW  - Age Factors
KW  - Aged
KW  - Aged, 80 and Over
KW  - Anticoagulants -- Administration and Dosage
KW  - Atrial Fibrillation -- Complications
KW  - Data Collection
KW  - Drug Monitoring -- Methods
KW  - Female
KW  - Human
KW  - Male
KW  - Middle Age
KW  - Sex Factors
KW  - Stroke -- Etiology
KW  - Stroke -- Prevention and Control
KW  - Warfarin -- Administration and Dosage
SP  - 432
EP  - 435
JO  - American Journal of Therapeutics
JF  - American Journal of Therapeutics
JA  - AM J THER
VL  - 19
IS  - 6
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - Although the oral anticoagulant warfarin has undoubtedly saved lives and reduced the number of strokes in patients with atrial fibrillation, it is a cumbersome medication to manage and take. Novel oral anticoagulants, such as dabigatran, offer therapeutic anticoagulation without requisite blood testing or dietary restrictions. We conducted a survey of the attitudes of patients enrolled in a warfarin clinic toward switching to a novel anticoagulant. From September to December 2010, a written survey was offered to 180 patients in the Warfarin Clinic of the Rush University Medical Center and 155 patients filled out the survey (86% response rate). Inclusion criteria included being 18 years of age or older, on warfarin for 2 months. Fifty-eight percent of patients were willing to switch anticoagulants. Women were significantly less willing to switch from warfarin than men (31 of 71, 44% vs. 54 of 78, 69%; P = 0.003). Patients older than 70 years were significantly more willing to switch anticoagulants than those younger than 70 years (48 of 68, 71% vs. 38 of 75, 51%; P = 0.017). There are significant differences across age and gender in the initial willingness of patients to accept novel anticoagulants. These differences may have important implications in the prevention and treatment of thromboembolic events.
SN  - 1075-2765
AD  - Department of Cardiology, Rush University Medical Center, Chicago, IL.
U2  - PMID: 22198071.
DO  - 10.1097/MJT.0b013e3182373591
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104571439
T1  - Subclinical hyperthyroidism: what it means to you.
Y1  - 2011/04/15/
N1  - Accession Number: 104571439. Language: English. Entry Date: 20120511. Revision Date: 20150711. Publication Type: Journal Article; consumer/patient teaching materials. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 1272646. 
KW  - Hyperthyroidism -- Blood
KW  - Hyperthyroidism -- Complications
KW  - Hyperthyroidism -- Etiology
KW  - Age Factors
KW  - Aged
KW  - Atrial Fibrillation -- Etiology
KW  - Diet -- Adverse Effects
KW  - Goiter -- Complications
KW  - Iodine Compounds -- Adverse Effects
KW  - Thyroid Hormones -- Blood
KW  - Virus Diseases -- Complications
SP  - 943
EP  - 944
JO  - American Family Physician
JF  - American Family Physician
JA  - AM FAM PHYSICIAN
VL  - 83
IS  - 8
CY  - Skokie, Illinois
PB  - American Academy of Family Physicians
SN  - 0002-838X
U2  - PMID: 21524034.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104426096
T1  - Summaries of recent papers.
Y1  - 2012/09//
N1  - Accession Number: 104426096. Language: English. Entry Date: 20121022. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary; tables/charts. Original Study: Suzuki M, Muro S, Ando Y, et al. A randomised, placebo-controlled trial of acupuncture in patients with chronic obstructive pulmonary disease (COPD). Arch Intern Med 2012; 172: 878-886; Colagiuri B, Smith CA. A systematic review of the effect of expectancy on treatment responses to acupuncture. Evid Based Complement Alternat Med 2012; 2012; Enblom A, Johnsson A, Hammar M, et al. Acupuncture compared with placebo acupuncture in radiotherapy-induced nausea—a randomized controlled study. Ann Oncol 2012; 23: 1353-1361; Zheng CH, Huang YH, Zhang MM et al. Effects of acupuncture on pregnancy rates in women undergoing in vitro fertilization: a systematic review and meta-analysis. Fertil Steril 2012; 97: 599-611; Manheimer E, Wieland LS, Cheng K, et al. Acupuncture for irritable bowel syndrome: systematic review and meta-analysis. Cochrane Database Syst Rev 2012; 16; Lombardi F, Belletti S, et al. Acupuncture for paroxysmal and persistent atrial fibrillation: an effective non-pharmacological tool? World J Cardiol 2012; 4: 60-65. Journal Subset: Alternative/Complementary Therapies; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. NLM UID: 9304117. 
KW  - Acupuncture
KW  - Acupressure
KW  - Alternative Therapies
KW  - Migraine -- Therapy
KW  - Randomized Controlled Trials
KW  - Chemotherapy, Cancer -- Adverse Effects
KW  - Nausea and Vomiting -- Therapy
KW  - Radiotherapy -- Adverse Effects
KW  - Pulmonary Disease, Chronic Obstructive -- Therapy
KW  - Stroke -- Rehabilitation
KW  - Atrial Fibrillation -- Therapy
KW  - Fertilization in Vitro
KW  - Irritable Bowel Syndrome
KW  - Research Methodology
KW  - Research Subjects
KW  - Hyperalgesia
SP  - 235
EP  - 242
JO  - Acupuncture in Medicine
JF  - Acupuncture in Medicine
JA  - ACUPUNCTURE MED
VL  - 30
IS  - 3
PB  - BMJ Publishing Group
SN  - 0964-5284
DO  - 10.1136/acupmed-2012-010204
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108142507
T1  - Tai chi exercise for patients with heart disease: a systematic review of controlled clinical trials.
AU  - Ng, Siu-Man
AU  - Wang, Chong-Wen
AU  - Tin-Hung Ho, Rainbow
AU  - Tat-Chi Ziea, Eric
AU  - He, J
AU  - Chi-Woon Taam Wong, Vivian
AU  - Lai-Wan Chan, Cecilia
Y1  - 2012/05//May/Jun2012
N1  - Accession Number: 108142507. Language: English. Entry Date: 20120921. Revision Date: 20150712. Publication Type: Journal Article; research; systematic review. Journal Subset: Alternative/Complementary Therapies; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Evidence-Based Practice. Instrumentation: Jadad Scale. NLM UID: 9502013. 
KW  - Coronary Disease -- Rehabilitation
KW  - Medical Practice, Evidence-Based
KW  - Quality of Life
KW  - Tai Chi
KW  - Activities of Daily Living
KW  - Clinical Assessment Tools
KW  - Health Behavior
KW  - Human
KW  - Myocardial Infarction -- Rehabilitation
KW  - Outcome Assessment
KW  - Randomized Controlled Trials
KW  - Scales
KW  - Study Design
KW  - Systematic Review
SP  - 16
EP  - 22
JO  - Alternative Therapies in Health & Medicine
JF  - Alternative Therapies in Health & Medicine
JA  - ALTERN THER HEALTH MED
VL  - 18
IS  - 3
CY  - Eagan, Minnesota
PB  - PH Innovisions Journal Operating LLC
AB  - CONTEXT: To summarize and evaluate the available evidence from controlled clinical trials of tai chi (TC) exercise for patients with heart disease. SEARCH METHODS: Fourteen databases were searched up to November 2010 with the terms tai chi, taichi, tai ji, taiji, taijichuan, cardiac, heart, coronary, myocardial, and atrial fibrillation in the title, abstract, or key words. No language restrictions were imposed. The quality and validity of randomized clinical trials (RCTs) were evaluated using the Jadad Scale. The strength of the evidence for all included studies was evaluated using the Oxford Centre for Evidence-based Medicine Levels of Evidence. RESULTS: Nine studies including 5 RCTs and 4 nonrandomized controlled clinical trials met the inclusion criteria. Three studies examined the effectiveness of TC exercise for patients with chronic heart failure (CHF), and 6 studies examined the effectiveness of TC exercise among patients with coronary heart disease (CHD). Overall, these studies demonstrated favorable effects of TC exercise for the patients with heart disease. CONCLUSIONS: The existing evidence suggests that TC exercise is a good option for heart patients with very limited exercise tolerance and can be an adjunct to rehabilitation programs for patients with CHD or CHF.
SN  - 1078-6791
AD  - Centre on Behavioral Health and Department of Social Work and Social Administration, University of Hong Kong.
U2  - PMID: 22875558.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107837764
T1  - Telling AFib.
AU  - Harris, Mark
Y1  - 2014/11//Nov/Dec2014
N1  - Accession Number: 107837764. Language: English. Entry Date: 20141112. Revision Date: 20150820. Publication Type: Journal Article; pictorial. Journal Subset: Allied Health; USA. NLM UID: 101167420. 
KW  - Atrial Fibrillation
KW  - Baby Boomers
KW  - Aging
KW  - Anticoagulants -- Therapeutic Use
KW  - Antiarrhythmia Agents -- Therapeutic Use
KW  - Administration, Oral
KW  - Atrial Fibrillation -- Complications
KW  - Stroke -- Etiology
KW  - Stroke -- Risk Factors
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Atrial Fibrillation -- Surgery
KW  - Hospitalization
KW  - Practice Guidelines
KW  - Diet
KW  - Warfarin -- Therapeutic Use
SP  - 26
EP  - 31
JO  - CMA Today
JF  - CMA Today
JA  - CMA TODAY
VL  - 47
IS  - 6
CY  - Chicago, Illinois
PB  - American Association of Medical Assistants
SN  - 1543-2998
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 110536915
T1  - Temporal changes in the use and results of exercise echocardiography.
AU  - Bouzas-Mosquera, Alberto
AU  - Peteiro, Jesús
AU  - Broullón, Francisco J.
AU  - Calviño-Santos, Ramón
AU  - Mosquera, Víctor X.
AU  - Sánchez-Fernández, Gabriel
AU  - Barbeito-Caamaño, Cayetana
AU  - Pérez-Cebey, Lucía
AU  - Martínez, Dolores
AU  - Yáñez, Juan C.
AU  - lvarez-García, Nemesio Á
AU  - Vázquez-Rodríguez, José Manuel
Y1  - 2015/11//
N1  - Accession Number: 110536915. Language: English. Entry Date: 20151030. Revision Date: 20160511. Publication Type: Article. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. 
KW  - Exercise
KW  - Echocardiography -- Methods
KW  - Exercise Test, Cardiopulmonary -- Evaluation
KW  - Cardiology
KW  - Human
KW  - Referral and Consultation
KW  - Patient Assessment
KW  - Cardiovascular Risk Factors
KW  - Invasive Procedures
KW  - Electrocardiography
KW  - Myocardial Revascularization
KW  - Coronary Disease -- Diagnosis
KW  - Myocardial Ischemia
KW  - After Care
KW  - Data Analysis
KW  - Descriptive Statistics
KW  - Atrial Fibrillation
KW  - Demography
KW  - Comorbidity
KW  - Diabetes Mellitus
KW  - Myocardial Infarction -- Diagnosis
KW  - Male
KW  - Female
KW  - Middle Age
KW  - Smoking -- Evaluation
KW  - Hyperlipidemia
KW  - Hypertension
KW  - Coronary Artery Bypass
KW  - Atrial Fibrillation -- Diagnosis
KW  - Angina Pectoris
KW  - Dyspnea
KW  - Heart Diseases -- Therapy
KW  - Adrenergic Beta-Antagonists -- Administration and Dosage
KW  - Calcium Channel Blockers
KW  - Nitrates
KW  - Angiotensin II Type I Receptor Blockers
KW  - Angiotensin-Converting Enzyme Inhibitors
KW  - Ischemia -- Diagnosis
SP  - 1207
EP  - 1212
JO  - European Heart Journal - Cardiovascular Imaging
JF  - European Heart Journal - Cardiovascular Imaging
JA  - EUR HEART J CARDIOVASC IMAGING
VL  - 16
IS  - 11
PB  - Oxford University Press / USA
SN  - 2047-2404
AD  - Unidad de Imagen y Función Cardíacas, Servicio de Cardiología, Complexo Hospitalario Universitario ACoruña, Instituto de Investigación Biomédica de ACoruña (INIBIC), As Xubias, 84,ACoruña 15006, Spain
AD  - Departamento de Tecnologías de la Informació n, Complexo Hospitalario UniversitarioACoruña, Instituto de Investigación Biomédica deACoruña (INIBIC), A Coruña, Spain
AD  - Unidad de Hemodinámica, Servicio de Cardiología, Complexo Hospitalario Universitario A Coruña, Instituto de Investigación Biomédica de A Coruña (INIBIC), A Coruña, Spain
AD  - Servicio de Cirugía Cardiaca, Complexo Hospitalario Universitario A Coruña, Instituto de Investigación Biomédica de A Coruña (INIBIC), A Coruña, Spain
DO  - 10.1093/ehjci/jev068
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105009450
T1  - The Anatomy and Physiology of the Sinoatrial Node-A Contemporary Review.
AU  - Monfredi O
AU  - Dobrzynski H
AU  - Mondal T
AU  - Boyett MR
AU  - Morris GM
Y1  - 2010/11//
N1  - Accession Number: 105009450. Language: English. Entry Date: 20101115. Revision Date: 20150711. Publication Type: Journal Article; pictorial; review; tables/charts. Journal Subset: Allied Health; Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7803944. 
KW  - Sinoatrial Node -- Anatomy and Histology
KW  - Electrophysiology
KW  - Sinoatrial Node -- Physiology
KW  - Potassium -- Physiology
KW  - Calcium -- Physiology
SP  - 1392
EP  - 1406
JO  - Pacing & Clinical Electrophysiology
JF  - Pacing & Clinical Electrophysiology
JA  - PACING CLIN ELECTROPHYSIOL
VL  - 33
IS  - 11
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - The sinoatrial node is the primary pacemaker of the heart. Nodal dysfunction with aging, heart failure, atrial fibrillation, and even endurance athletic training can lead to a wide variety of pathological clinical syndromes. Recent work utilizing molecular markers to map the extent of the node, along with the delineation of a novel paranodal area intermediate in characteristics between the node and the surrounding atrial muscle, has shown that pacemaker tissue is more widely spread in the right atrium than previously appreciated. This can explain the phenomenon of a 'wandering pacemaker' and concomitant changes in the P-wave morphology. Extensive knowledge now exists regarding the molecular architecture of the node (in particular, the expression of ion channels) and how this relates to pacemaking. This review is an up-to-date summary of the current state of our appreciation of the above topics. (PACE 2010; 1392-1406)
SN  - 0147-8389
AD  - Cardiovascular Medicine, Faculty of Medical and Human Sciences, University of Manchester, Core Technology Facility, Manchester, United Kingdom
DO  - 10.1111/j.1540-8159.2010.02838.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106495495
T1  - The benefits of thought field therapy.
AU  - Stone C
Y1  - 2005/05//
N1  - Accession Number: 106495495. Language: English. Entry Date: 20050805. Revision Date: 20150711. Publication Type: Journal Article; tables/charts. Journal Subset: Alternative/Complementary Therapies; Europe; UK & Ireland. NLM UID: 100894952. 
KW  - Alternative Therapies
KW  - Mental Processes
KW  - Atrial Fibrillation -- Therapy
KW  - Heart Rate Variability
KW  - Meridians
KW  - Psychological Well-Being
SP  - 22
EP  - 24
JO  - Positive Health
JF  - Positive Health
JA  - POSITIVE HEALTH
IS  - 111
PB  - Compass Internet Ltd
SN  - 1356-3963
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104445968
T1  - The calming effect of yoga.
Y1  - 2012/05//
N1  - Accession Number: 104445968. Language: English. Entry Date: 20120516. Revision Date: 20150711. Publication Type: Journal Article; brief item; questions and answers. Journal Subset: Consumer Health; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Consumer Health. NLM UID: 9425420. 
KW  - Yoga
KW  - Atrial Fibrillation -- Therapy
SP  - 6
EP  - 6
JO  - Consumer Reports on Health
JF  - Consumer Reports on Health
JA  - CONSUM REP HEALTH
VL  - 24
IS  - 5
CY  - Yonkers, New York
PB  - Consumers Union
SN  - 1044-3193
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106918927
T1  - The clinic. Atrial fibrillation: can I keep running?
AU  - Grzesiak JP
AU  - Miller T
Y1  - 2001/09//2001 Sep
N1  - Accession Number: 106918927. Language: English. Entry Date: 20020426. Revision Date: 20150711. Publication Type: Journal Article; questions and answers. Journal Subset: Consumer Health; USA. NLM UID: 9881265. 
KW  - Atrial Fibrillation
KW  - Running
SP  - 6
EP  - 6
JO  - Running & FitNews
JF  - Running & FitNews
JA  - RUN FITNEWS
VL  - 19
IS  - 9
CY  - Bethesda, Maryland
PB  - American Running Association
SN  - 0898-5162
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106918927&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107200714
T1  - The clinic. Coumadin effect on running.
AU  - Ives TL
AU  - Gitler B
AU  - Goldman AP
AU  - Miller TD
Y1  - 1999/04//1999 Apr
N1  - Accession Number: 107200714. Language: English. Entry Date: 19990701. Revision Date: 20150711. Publication Type: Journal Article; brief item. Journal Subset: Consumer Health; USA. NLM UID: 9881265. 
KW  - Running
KW  - Warfarin
KW  - Atrial Fibrillation -- Drug Therapy
SP  - 7
EP  - 7
JO  - Running & FitNews
JF  - Running & FitNews
JA  - RUN FITNEWS
VL  - 17
IS  - 4
CY  - Bethesda, Maryland
PB  - American Running Association
SN  - 0898-5162
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107200714&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106740323
T1  - The clinic. Don't ignore exertional heart irregularities.
AU  - Moffitt R
AU  - Hubbard JM
AU  - Jimenez C
AU  - Williams M
AU  - Bloom M
Y1  - 2003/07//
N1  - Accession Number: 106740323. Language: English. Entry Date: 20040528. Revision Date: 20150711. Publication Type: Journal Article; questions and answers. Journal Subset: Consumer Health; USA. NLM UID: 9881265. 
KW  - Running
KW  - Heart Block -- Complications
KW  - Atrial Fibrillation -- Etiology
KW  - Exertion
SP  - 7
EP  - 7
JO  - Running & FitNews
JF  - Running & FitNews
JA  - RUN FITNEWS
VL  - 21
IS  - 4
CY  - Bethesda, Maryland
PB  - American Running Association
SN  - 0898-5162
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106740323&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107346791
T1  - The clinic. Rapid heart beat.
AU  - Thornburgh G
AU  - Schulman C
AU  - Miller T
Y1  - 1997/06//1997 Jun
N1  - Accession Number: 107346791. Language: English. Entry Date: 19971101. Revision Date: 20150711. Publication Type: Journal Article; brief item. Journal Subset: Consumer Health; USA. NLM UID: 9881265. 
KW  - Atrial Fibrillation
KW  - Running
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Atrial Fibrillation -- Therapy
SP  - 6
EP  - 6
JO  - Running & FitNews
JF  - Running & FitNews
JA  - RUN FITNEWS
VL  - 15
IS  - 6
CY  - Bethesda, Maryland
PB  - American Running Association
SN  - 0898-5162
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107346791&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104833149
T1  - The effect of a fibre supplement compared to a healthy diet on body composition, lipids, glucose, insulin and other metabolic syndrome risk factors in overweight and obese individuals.
AU  - Pal, Sebely
AU  - Khossousi, Alireza
AU  - Binns, Colin
AU  - Dhaliwal, Satvinder
AU  - Ellis, Vanessa
Y1  - 2011/01//1/1/2011
N1  - Accession Number: 104833149. Language: English. Entry Date: 20110311. Revision Date: 20150711. Publication Type: Journal Article; research; randomized controlled trial. Journal Subset: Allied Health; Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Special Interest: Nutrition. NLM UID: 0372547. 
KW  - Diet
KW  - Dietary Fiber -- Therapeutic Use
KW  - Insulin -- Blood
KW  - Lipids -- Blood
KW  - Metabolic Syndrome X -- Prevention and Control
KW  - Obesity -- Diet Therapy
KW  - Psyllium -- Therapeutic Use
KW  - Adipose Tissue
KW  - Adult
KW  - Antilipemic Agents -- Administration and Dosage
KW  - Antilipemic Agents -- Pharmacodynamics
KW  - Antilipemic Agents -- Therapeutic Use
KW  - Biological Products -- Pharmacodynamics
KW  - Biological Products -- Therapeutic Use
KW  - Body Composition
KW  - Body Mass Index
KW  - Body Weight
KW  - Dietary Fiber -- Administration and Dosage
KW  - Dietary Fiber -- Pharmacodynamics
KW  - Dietary Supplements
KW  - Female
KW  - Human
KW  - Male
KW  - Medicine, Herbal
KW  - Metabolic Syndrome X -- Blood
KW  - Middle Age
KW  - Obesity -- Blood
KW  - Psyllium -- Pharmacodynamics
KW  - Randomized Controlled Trials
KW  - Risk Factors
KW  - Single-Blind Studies
SP  - 90
EP  - 100
JO  - British Journal of Nutrition
JF  - British Journal of Nutrition
JA  - BR J NUTR
VL  - 105
IS  - 1
PB  - Cambridge University Press
AB  - Optimum levels and types of dietary fibre that provide the greatest beneficial effects on metabolic syndrome risk factors in overweight and obese individuals have yet to be determined in clinical trials. The present parallel design study compared the effects of fibre intake from a healthy diet v. a fibre supplement (psyllium) or a healthy diet plus fibre supplement on fasting lipids, glucose, insulin and body composition. Overweight/obese adults were randomised to either control (with placebo), fibre supplement (FIB), healthy eating plus placebo (HLT) or healthy eating plus fibre supplement (HLT-FIB). There was a significant increase in fibre intake in HLT-FIB, HLT and FIB groups up to 59, 31 and 55 g, respectively, at 12 weeks when compared to control (20 g). Weight, BMI and % total body fat were significantly reduced in FIB and HLT-FIB groups, with weight and BMI significantly reduced in the HLT group compared with control at 12 weeks. HLT-FIB and HLT groups had significant reductions in TAG and insulin compared with control at 6 and 12 weeks, and in insulin compared with the FIB group at 12 weeks. The HLT-FIB, HLT and FIB groups all had significant reductions in total cholesterol and LDL-cholesterol compared with control after 6 and 12 weeks. The present study demonstrated that simply adding psyllium fibre supplementation to a normal diet was sufficient to obtain beneficial effects in risk factors. However, a high-fibre diet consisting of a psyllium supplement plus fibre from a healthy diet provided the greatest improvements in metabolic syndrome risk factors.
SN  - 0007-1145
AD  - School of Public Health, Curtin Health Innovation Research Institute, ATN Centre for Metabolic Fitness, Curtin University of Technology, GPO Box U1987, Perth, WA, Australia 6485. s.pal@curtin.edu.au
AD  - School of Public Health, Curtin Health Innovation Research Institute, ATN Centre for Metabolic Fitness, Curtin University of Technology, GPO Box U1987, Perth, WA, Australia 6485.
U2  - PMID: 20727237.
DO  - 10.1017/S0007114510003132
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107187155
T1  - The effect of maximum heart rate on oxygen kinetics and exercise performance at low and high workloads.
AU  - Carmouche DG
AU  - Bubien RS
AU  - Kay GN
Y1  - 1998/04//
N1  - Accession Number: 107187155. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Allied Health; Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Instrumentation: Borg Scale of Perceived Exertion. NLM UID: 7803944. 
KW  - Exercise Physiology
KW  - Oxygen Consumption
KW  - Heart Rate
KW  - Pacemaker, Artificial
KW  - Heart Block -- Physiopathology
KW  - Heart Block -- Therapy
KW  - Exercise Test, Cardiopulmonary
KW  - Atrioventricular Node -- Surgery
KW  - Treadmills
KW  - Kinetics
KW  - Workload
KW  - Clinical Assessment Tools
KW  - T-Tests
KW  - Wilcoxon Signed Rank Test
KW  - Adult
KW  - Middle Age
KW  - Aged
KW  - Female
KW  - Male
KW  - Human
SP  - 679
EP  - 686
JO  - Pacing & Clinical Electrophysiology
JF  - Pacing & Clinical Electrophysiology
JA  - PACING CLIN ELECTROPHYSIOL
VL  - 21
IS  - 4P1
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - The normal heart rate is linearly related to oxygen consumption during exercise. The maximum heart rate of the normal sinus node is approximated by the formula: HRmax = (220-age) with a variance of approximately 15%. However, the nominal upper rate of most permanent pacemakers is 120 beats/min, a value that remains unchanged for many patients. As this nominal setting falls well below the maximum predicted heart rate for most patients, it is possible that the chronotropic response of rate adaptive pacemakers during moderate and maximal exercise workloads may be less than optimal. The purpose of this study was to determine the effect of the upper programmed rate on oxygen kinetics during submaximal exercise workloads and maximum exercise performance during symptom-limited treadmill exercise. Exercise performance with an upper rate programmed to 220-age was compared with an upper rate of 120 beats/min. Eleven patients (5 men and 6 women, mean age 54 +/- 10 years) with complete heart block following catheter ablation of the atrioventricular junction for refractory atrial fibrillation who were implanted with permanent, rate-modulating VVIR pacemakers comprised the study population. The rate adaptive sensors were based on activity in 8 patients, minute ventilation in 2 patients, and mixed venous oxygen saturation in 1 patient. After performing a symptom-limited treadmill exercise test to determine maximum exercise capacity and to optimized programming of the rate adaptive sensor, each subject performed two treadmill exercise tests in random sequence with a rest period of at least 1 hour between tests. During one of the tests the upper rate was programmed to a value calculated by the formula: HRmax = (220-age). During the other exercise test the upper rate was programmed to 120 beats/min. Patients were blinded as to their programmed values and to the hypothesis of the study. A novel treadmill exercise protocol was used that consisted of a 6 minute, constant-workload phase at approximately 50% of maximum workload followed immediately by incremental, symptom-limited exercise using a modified Chronotropic Assessment Exercise Protocol(CAEP) with 1 minute stages until; peak exertion. Breath-by-breath analysis of expired gases was performed with subjective scoring of exertional difficulty at the end of the constant workload phase and during each stage of incremental exercise using the Borg Perceived Exertion Scale. Exercise duration was significantly longer (637 +/- 47 vs 611 +/- 48 seconds, P < 0.005) with the higher programmed upper rate. Oxygen kinetics were also significantly improved with an age predicted upper rate with a lower O2 deficit (258 +/- 88 vs 395 +/- 155 mL, P = 0.002) and higher VO2 rate constant (3.6 +/- 1.0 vs 2.4 +/- 0.7, P < 0.001). The VO2max during peak exertion was higher with an age predicted upper rate than with an upper rate of 120 beats/min (1807 +/- 751 vs 1716 +/- 702 mL/min, P = 0.04). The mean Borg score was lower during the last common treadmill stage during maximum exercise with an age predicted upper rate than with an upper rate of 120 beats/min (15.7 +/- 2.0 vs 16.5 +/- 1.9, P = 0.04). The mean Borg score during submaximal, constant workload exercise was also lower with a higher upper rate (9.0 +/- 2.5 vs 9.6 +/- 2.2, P = 0.10). Programming the upper rate of rate adaptive pacemakers based on the age of the patient improves exercise performance and exertional symptoms during both low and high exercise workloads as compared with a standard nominal value of 120 beats/min.
SN  - 0147-8389
AD  - University of Alabama at Birmingham
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109755330
T1  - The efficacy of rivaroxaban in patients with atrial fibrillation.
AU  - Carag, Michael R
AU  - Arora, Rohit R
Y1  - 2014/09//2014 Sep-Oct
N1  - Accession Number: 109755330. Language: English. Entry Date: 20150828. Revision Date: 20150923. Publication Type: Journal Article; review. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9441347. 
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Anticoagulants -- Therapeutic Use
KW  - Heterocyclic Compounds -- Therapeutic Use
KW  - Sulfur Compounds -- Therapeutic Use
KW  - Heterocyclic Compounds -- Adverse Effects
KW  - Stroke -- Prevention and Control
KW  - Sulfur Compounds -- Adverse Effects
KW  - Warfarin -- Therapeutic Use
SP  - 412
EP  - 418
JO  - American Journal of Therapeutics
JF  - American Journal of Therapeutics
JA  - AM J THER
VL  - 21
IS  - 5
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - Atrial fibrillation (AF), the most common form of cardiac arrhythmia, is a major risk factor for cardioembolic stroke. Dose-adjusted warfarin has been the gold standard for stroke prophylaxis in moderate- to high-risk patients with AF. However, the use of warfarin therapy is greatly limited by its narrow therapeutic window, numerous dietary restrictions, and drug-drug interactions, and an increased risk of hemorrhage. As a result, great emphasis has been placed on developing a new anticoagulant agent with fewer risks and limitations. Current data suggest that the oral direct factor Xa inhibitor rivaroxaban is a safe and effective alternative to warfarin. Furthermore, rivaroxaban does not require routine coagulation monitoring, which may improve patient compliance to anticoagulant therapy. The ROCKET AF trial demonstrated that 20-mg oral rivaroxaban taken once daily was noninferior to dose-adjusted warfarin in the prevention of stroke and non-central nervous system systemic embolism and had a comparable risk of bleeding. Based primarily on the ROCKET AF trial results, the US Food and Drug Administration recently approved the use of rivaroxaban for stroke prophylaxis in patients with nonvalvular AF. However, additional postmarketing studies on its safety and cost effectiveness are needed before it can be widely accepted as a sound alternative to warfarin.
SN  - 1075-2765
U2  - PMID: 22487774.
DO  - 10.1097/MJT.0b013e3182491d8b
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107835252
T1  - The Feasibility of Increasing Exercise Adherence Through Education and Weekly Exercise Reminders.
AU  - English, Rebekah D.
AU  - Velasquez, Donna
AU  - Thrall, Charlotte
AU  - Ross, Heather M.
Y1  - 2014/09//Sep/Oct2014
N1  - Accession Number: 107835252. Language: English. Entry Date: 20140904. Revision Date: 20150712. Publication Type: Journal Article; abstract; research. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Instrumentation: Borg Perceived Exertion Scale; Short Form-36 Health Survey (SF-36); Symptoms Checklist: Frequency and Severity Scale.. NLM UID: 8703516. 
KW  - Motivation
KW  - Patient Compliance
KW  - Exercise
KW  - Reminder Systems
KW  - Cardiac Patients
KW  - Human
KW  - Pilot Studies
KW  - Descriptive Statistics
KW  - Atrial Fibrillation
KW  - Convenience Sample
KW  - Short Form-36 Health Survey (SF-36)
KW  - Questionnaires
KW  - Scales
KW  - Exercise -- Education
SP  - 402
EP  - 402
JO  - Journal of Cardiovascular Nursing
JF  - Journal of Cardiovascular Nursing
JA  - J CARDIOVASC NURS
VL  - 29
IS  - 5
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
SN  - 0889-4655
AD  - Arizona State University, Phoenix, Arizona
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 113724868
T1  - THE IMPACT OF ATRIAL FIBRILLATION ON EXERCISE CAPACITY AND MORTALITY IN HEART FAILURE WITH PRESERVED EJECTION FRACTION: INSIGHTS FROM CARDIOPULMONARY STRESS TESTING.
AU  - Elshazly, Mohamed Badreldin
AU  - Wu, Yuping
AU  - Saliba, Walid
AU  - Wazni, Oussama
AU  - Cho, Leslie
Y1  - 2016/04/06/Apr2016 Supplement
N1  - Accession Number: 113724868. Language: English. Entry Date: In Process. Revision Date: 20160322. Publication Type: Article. Supplement Title: Apr2016 Supplement. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 8301365. 
SP  - 690
EP  - 690
JO  - Journal of the American College of Cardiology (JACC)
JF  - Journal of the American College of Cardiology (JACC)
JA  - J AM COLL CARDIOL
VL  - 67
IS  - 13S
CY  - New York, New York
PB  - Elsevier Science
SN  - 0735-1097
AD  - Cleveland Clinic, Cleveland, OH, USA
DO  - 10.1016/S0735-1097(16)30691-X
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107890834
T1  - The impact of smoking on thromboembolism and mortality in patients with incident atrial fibrillation: insights from the danish diet, cancer, and health study.
AU  - Albertsen, Ida Ehlers
AU  - Rasmussen, Lars Hvilsted
AU  - Lane, Deirdre A
AU  - Overvad, Thure Filskov
AU  - Skjøth, Flemming
AU  - Overvad, Kim
AU  - Lip, Gregory Y H
AU  - Larsen, Torben Bjerregaard
Y1  - 2014/03//
N1  - Accession Number: 107890834. Language: English. Entry Date: 20140509. Revision Date: 20150712. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Critical Care. NLM UID: 0231335. 
KW  - Atrial Fibrillation -- Complications
KW  - Diet
KW  - Data Collection
KW  - Smoking
KW  - Thromboembolism -- Epidemiology
KW  - Atrial Fibrillation -- Mortality
KW  - Cause of Death -- Trends
KW  - Denmark
KW  - Female
KW  - Prospective Studies
KW  - Human
KW  - Incidence
KW  - Male
KW  - Middle Age
KW  - Prognosis
KW  - Risk Factors
KW  - Smoking -- Mortality
KW  - Thromboembolism -- Etiology
KW  - Thromboembolism -- Prevention and Control
KW  - Time Factors
SP  - 559
EP  - 566
JO  - CHEST
JF  - CHEST
JA  - CHEST
VL  - 145
IS  - 3
CY  - Glenview, Illinois
PB  - American College of Chest Physicians
AB  - BACKGROUND: Smoking and atrial fibrillation (AF) are major health problems worldwide and are responsible for substantial health-care costs. Our aim was to investigate whether smoking impacts the risk of stroke and death in patients with AF. To test this hypothesis, we analyzed data from a large Danish cohort: the Diet, Cancer, and Health study. METHODS: This was a cohort study of 57,053 people (27,178 men; 29,876 women) aged 50 to 64 years. The risk of thromboembolism (ischemic stroke/arterial thromboembolism) or death according to smoking habits among 3,161 patients with incident AF (mean age, 66.9 years; 2,032 men, 1,129 women) was assessed using Cox proportional hazard models after a median follow-up of 4.9 years. RESULTS: Of those with AF, 34% were current smokers and 37% former smokers. After adjustment for vitamin K antagonist treatment, the hazard ratios (HRs) (95% CI) of thromboembolism or death were 3.13 (1.72-6.37) and 2.73 (2.02-3.70) among women and men who currently were heavy smokers ( 25 g/d), respectively. The associations remained after adjustment for well-established risk factors with HRs of 3.64 (1.88-7.07) and 2.17 (1.59-2.95) among women and men, respectively. In a sensitivity analysis, smoking was still strongly associated with thromboembolism or death after censoring people with a cancer diagnosis during follow-up. CONCLUSIONS: Smoking is associated with a higher risk of thromboembolism or death in patients with AF even after adjusting for well-recognized risk factors used in stroke risk stratification schemes. The associations may be modified by sex, as the associations were strongest among women.
SN  - 0012-3692
U2  - PMID: 24091709.
DO  - 10.1378/chest.13-1740
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104953558
T1  - The nurse's role in the management of atrial fibrillation.
AU  - Greener, Mark
Y1  - 2010/11//
N1  - Accession Number: 104953558. Language: English. Entry Date: 20110128. Revision Date: 20150818. Publication Type: Journal Article. Journal Subset: Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 101175794. 
KW  - Atrial Fibrillation
KW  - Atrial Fibrillation -- Classification
KW  - Atrial Fibrillation -- Complications
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Atrial Fibrillation -- Epidemiology
KW  - Atrial Fibrillation -- Nursing
KW  - Atrial Fibrillation -- Risk Factors
KW  - Atrial Fibrillation -- Symptoms
KW  - Nursing Role
SP  - 532
EP  - 537
JO  - Nurse Prescribing
JF  - Nurse Prescribing
JA  - NURSE PRESCRIBING
VL  - 8
IS  - 11
PB  - MA Healthcare Limited
AB  - Atrial fibrillation (AF) is the most common sustained arrhythmia. Despite increasing overall mortality by up to 90%, many health professionals do not regard AF as a modifiable cardiovascular risk factor, a view this article challenges. Nurses can make several potentially influential contributions to the detection and management of this increasingly common disease. AF predominantly develops among older people, who often receive nursing care. Furthermore, numerous diseases, conditions and risk factors managed by nurses cause or contribute to AF, including cardiac and metabolic conditions, certain surgical procedures, diet and lifestyle. As most episodes are asymptomatic, nurses should consider AF in any patient with an irregular pulse, and refer suspected cases for an electrocardiogram. AF management aims to alleviate symptoms and prevent complications using antithrombotics, cardioversion, antiarrhythmics, or ablation therapy. Traditional antiarrhythmic drugs are only moderately effective in AF and can cause potentially serious adverse effects. Future and recently launched AF medications may offer improved efficacy and safety.
SN  - 1479-9189
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105859000
T1  - The resting electrocardiogram in the management of patients with congestive heart failure: established applications and new insights.
AU  - Madias JE
Y1  - 2007/01//
N1  - Accession Number: 105859000. Language: English. Entry Date: 20080314. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Allied Health; Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7803944. 
KW  - Electrocardiography
KW  - Heart Failure -- Diagnosis
KW  - Heart Failure -- Therapy
KW  - Aged
KW  - Female
KW  - Heart Failure -- Physiopathology
KW  - Male
KW  - Middle Age
KW  - Relaxation
SP  - 123
EP  - 128
JO  - Pacing & Clinical Electrophysiology
JF  - Pacing & Clinical Electrophysiology
JA  - PACING CLIN ELECTROPHYSIOL
VL  - 30
IS  - 1
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - The resting electrocardiogram (ECG) furnishes essential information for the diagnosis, management, and prognostic evaluation of patients with congestive heart failure (CHF). Almost any ECG diagnostic entity may turn out to be useful in the care of patients with CHF, revealing the non-specificity of the ECG in CHF. Nevertheless a number of CHF/ECG correlates have been proposed and found to be indispensable in clinical practice; they include, among others, the ECG diagnoses of myocardial ischemia and infarction, atrial fibrillation, left ventricular hypertrophy/dilatation, left bundle branch block and intraventricular conduction delays, left atrial abnormality, and QT-interval prolongation. In addition to the above well-known applications of the ECG for patients with CHF, a recently described association of peripheral edema (PERED), sometimes even imperceptible by physical examination, with attenuated ECG potentials, could extend further the diagnostic range of the clinician. These ECG voltage attenuations are of extracardiac mechanism, and impact the amplitude of QRS complexes, P-waves, and T-waves, occasionally resulting also in shortening of the QRS complex and QT interval duration. PERED alleviation, in response to therapy of CHF, reverses all above alterations. These fresh diagnostic insights have potential application in the follow-up of patients with CHF, and in their selection for implantation of cardioverter/defibrillator and/or cardiac resynchronization systems. If sought, PERED-induced ECG changes are abundantly present in the hospital and clinic environments; if their detection and monitoring are incorporated in the clinician's 'routine,' considerable improvements in the care of patients with CHF may be realized.
SN  - 0147-8389
AD  - Mount Sinai School of Medicine of the New York University and the Division of Cardiology, Elmhurst Hospital Center, New York 11373, USA. madiasj@nychhc.org
U2  - PMID: 17241326.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106668736
T1  - The secondary prevention of ischemic stroke.
AU  - Tabereaux PB
AU  - Brass LM
AU  - Bravata DM
Y1  - 2004/06//2004 Jun
N1  - Accession Number: 106668736. Language: English. Entry Date: 20041126. Revision Date: 20150711. Publication Type: Journal Article; case study; CEU; exam questions; review; tables/charts. Journal Subset: Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Health Services Administration; Peer Reviewed; USA. NLM UID: 9503754. 
KW  - Stroke
KW  - Carotid Stenosis -- Complications
KW  - Cerebral Ischemia, Transient -- Prevention and Control
KW  - Stroke -- Drug Therapy
KW  - Stroke -- Prevention and Control
KW  - Stroke -- Risk Factors
KW  - Stroke -- Therapy
KW  - Diabetes Mellitus -- Complications
KW  - Education, Continuing (Credit)
KW  - Female
KW  - Hypertension -- Complications
KW  - Life Style Changes
KW  - Middle Age
KW  - Platelet Aggregation Inhibitors -- Therapeutic Use
KW  - Statins -- Therapeutic Use
KW  - Warfarin -- Therapeutic Use
SP  - 371
EP  - 384
JO  - Journal of Clinical Outcomes Management
JF  - Journal of Clinical Outcomes Management
JA  - JCOM
VL  - 11
IS  - 6
CY  - Wayne, Pennsylvania
PB  - Turner White Communications
AB  - Objective: To provide an overview of the evidence and clinical approach to secondary stroke prevention for patients following an ischemic stroke or transient ischemic attack (TIA).Methods: Overview of the literature.Results: Patients with acute ischemic strokes and TIAs are at increased risk for secondary vascular events, including recurrent stroke. Nonmodifiable risk factors should be evaluated to identify patients who are at high risk of recurrent stroke. Risk factor modification includes diagnosing and treating hyper-tension, hyperlipidemia, and diabetes. Patients with high-grade symptomatic carotid artery stenosis should be evaluated for carotid endarterectomy. Stroke patients with atrial fibrillation should receive warfarin unless a contraindication is present. All other stroke patients should receive an antiplatelet agent unless contraindicated. Recommendations for lifestyle changes, including stopping smoking, avoiding heavy alcohol use, reducing overweight, and increasing exercise, should be made during the acute stroke period.Conclusion: Post-stroke care should involve an assessment of both nonmodifiable and modifiable risk factors in all patients. Risk factor modifications should be initiated early after the first event.
SN  - 1079-6533
AD  - Dept of Internal Medicine, Yale University School of Medicine, New Haven, CT
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108200977
T1  - The use of acupuncture in the emergency room.
AU  - Cecconi, Alessandro
Y1  - 2011/10//
N1  - Accession Number: 108200977. Language: English. Entry Date: 20120106. Revision Date: 20150820. Publication Type: Journal Article; case study. Journal Subset: Alternative/Complementary Therapies; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Special Interest: Emergency Care. NLM UID: 8101969. 
KW  - Acupuncture -- Utilization
KW  - Emergency Service
KW  - Adult
KW  - Aged
KW  - Asthma -- Therapy
KW  - Atrial Fibrillation -- Therapy
KW  - Female
KW  - Fever -- Therapy
KW  - Hypertension -- Therapy
KW  - Kidney Calculi
KW  - Life Experiences
KW  - Male
KW  - Panic Disorder -- Therapy
KW  - Physician Attitudes
SP  - 56
EP  - 60
JO  - Journal of Chinese Medicine
JF  - Journal of Chinese Medicine
JA  - J CHINESE MED
IS  - 97
PB  - Journal of Chinese Medicine
AB  - Emergency Room (ER) doctors have to deal with sever health conditions that require swift intervention, usually with rapidly-acting drugs. There may appear to be no space for traditional Chinese medicine (TCM) -- and acupuncture in particular -- in this context, thanks to the widespread belief that this kind of traditional medicine requires more time to act. This article describes the use of TCM in an ER in Italy. Through the description of several cases the author shows that acupuncture can be effective either alone, or in combination with Western medicine, for both diagnosis and treatment of conditions not normally ween in private TCM clinics.
SN  - 0143-8042
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105930663
T1  - Tricuspid ring valve abscess in an AICD implanted patient.
AU  - Chandra P
AU  - Madan P
AU  - Paniagua D
Y1  - 2007/08/07/
N1  - Accession Number: 105930663. Language: English. Entry Date: 20080118. Revision Date: 20150711. Publication Type: Journal Article; case study; diagnostic images. Journal Subset: Biomedical; Editorial Board Reviewed; Peer Reviewed; USA. NLM UID: 101207289. 
KW  - Defibrillators, Implantable -- Adverse Effects
KW  - Heart Valve Diseases -- Microbiology
KW  - Methicillin Resistance
KW  - Staphylococcus Aureus
KW  - Tricuspid Valve -- Pathology
KW  - Aged
KW  - Atrial Fibrillation -- Therapy
KW  - Device Removal
KW  - Electrodes, Implanted
KW  - Male
KW  - Myocardial Diseases
KW  - Reoperation
SP  - 3p
EP  - 3p
JO  - Internet Journal of Cardiology
JF  - Internet Journal of Cardiology
JA  - INTERNET J CARDIOL
VL  - 4
IS  - 2
CY  - Sugar Land, Texas
PB  - Internet Scientific Publications LLC
AB  - A 73 year old Caucasian male with dilated cardiomyopathy, atrial fibrillation, and an automated implantable cardioverter defibrillator (AICD) placed 1 year ago presented with implant side soreness and methicillin resistant staphylococcus aureus (MRSA) bacteremia. EKG showed multiple runs of nonsustained ventricular tachycardia (NSVT). Transesophageal echocardiogram revealed a 4.2 cm size abscess on tricuspid valve ring at the site of electrode implantation.
SN  - 1528-834X
AD  - Department of Medicine, Baylor College of Medicine, Houston, TX; chandra@bcm.tmc.edu
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107802103
T1  - Twelve-single nucleotide polymorphism genetic risk score identifies individuals at increased risk for future atrial fibrillation and stroke.
AU  - Tada, Hayato
AU  - Shiffman, Dov
AU  - Smith, J Gustav
AU  - Sjögren, Marketa
AU  - Lubitz, Steven A
AU  - Ellinor, Patrick T
AU  - Louie, Judy Z
AU  - Catanese, Joseph J
AU  - Engström, Gunnar
AU  - Devlin, James J
AU  - Kathiresan, Sekar
AU  - Melander, Olle
Y1  - 2014/10//
N1  - Accession Number: 107802103. Language: English. Entry Date: 20150213. Revision Date: 20150712. Publication Type: Journal Article; research. Journal Subset: Allied Health; Biomedical; Peer Reviewed; USA. Special Interest: Physical Therapy. NLM UID: 0235266. 
KW  - Atrial Fibrillation
KW  - Disease Susceptibility
KW  - Polymorphism, Genetic
KW  - Stroke
KW  - Aged
KW  - Prospective Studies
KW  - Female
KW  - Genotype
KW  - Human
KW  - Male
KW  - Middle Age
KW  - Polymerase Chain Reaction
KW  - Cox Proportional Hazards Model
KW  - Risk Factors
SP  - 2856
EP  - 2862
JO  - Stroke (00392499)
JF  - Stroke (00392499)
JA  - STROKE
VL  - 45
IS  - 10
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - BACKGROUND AND PURPOSE: Atrial fibrillation (AF) is prevalent and there is a clinical need for biomarkers to identify individuals at higher risk for AF. Fixed throughout a life course and assayable early in life, genetic biomarkers may meet this need. Here, we investigate whether multiple single nucleotide polymorphisms together as an AF genetic risk score (AF-GRS) can improve prediction of one's risk for AF. METHODS: In 27 471 participants of the Malmö Diet and Cancer Study, a prospective, community-based cohort, we used Cox models that adjusted for established AF risk factors to assess the association of AF-GRS with incident AF and ischemic stroke. Median follow-up was 14.4 years for incident AF and 14.5 years for ischemic stroke. The AF-GRS comprised 12 single nucleotide polymorphisms that had been previously shown to be associated with AF at genome-wide significance. RESULTS: During follow-up, 2160 participants experienced a first AF event and 1495 had a first ischemic stroke event. Participants in the top AF-GRS quintile were at increased risk for incident AF (hazard ratio, 2.00; 95% confidence interval, 1.73-2.31; P=2.7x10(-21)) and ischemic stroke (hazard ratio, 1.23; 95% confidence interval, 1.04-1.46; P=0.02) when compared with the bottom quintile. Addition of the AF-GRS to established AF risk factors modestly improved both discrimination and reclassification (P<0.0001 for both). CONCLUSIONS: An AF-GRS can identify 20% of individuals who are at ~=2-fold increased risk for incident AF and at 23% increased risk for ischemic stroke. Targeting diagnostic or therapeutic interventions to this subset may prove clinically useful.
SN  - 0039-2499
AD  - From the Center for Human Genetic Research and Cardiovascular Research Center (H.T., S.A.L., P.T.E., S.K.) and Cardiac Arrhythmia Service (S.A.L., P.T.E.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (H.T., S.K.); Department of Medicine, Harvard Medical School, Boston, MA (H.T., P.T.E., S.K.); Quest Diagnostics, Science and Innovation Group, Alameda, CA (D.S., J.Z.L., J.J.C., J.J.D.); Department of Cardiology, Lund University, Lund, Sweden (J.G.S.); Department of Clinical Sciences, Lund University, Malmö, Sweden (M.S., G.E., O.M.); and Department of Internal Medicine, Skåne University Hospital, Malmö, Sweden (O.M.).
AD  - From the Center for Human Genetic Research and Cardiovascular Research Center (H.T., S.A.L., P.T.E., S.K.) and Cardiac Arrhythmia Service (S.A.L., P.T.E.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (H.T., S.K.); Department of Medicine, Harvard Medical School, Boston, MA (H.T., P.T.E., S.K.); Quest Diagnostics, Science and Innovation Group, Alameda, CA (D.S., J.Z.L., J.J.C., J.J.D.); Department of Cardiology, Lund University, Lund, Sweden (J.G.S.); Department of Clinical Sciences, Lund University, Malmö, Sweden (M.S., G.E., O.M.); and Department of Internal Medicine, Skåne University Hospital, Malmö, Sweden (O.M.). dov.shiffman@celera.com sekar@broadinstitute.org olle.melander@med.lu.se.
U2  - PMID: 25123217.
DO  - 10.1161/STROKEAHA.114.006072
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109745432
T1  - Unexplained acute chest pain in young adults: disease patterns and medication use 25 years later.
AU  - Roll, Martin
AU  - Rosenqvist, Mårten
AU  - Sjöborg, Bengt
AU  - Wettermark, Björn
Y1  - 2015/06//
N1  - Accession Number: 109745432. Language: English. Entry Date: 20150923. Revision Date: 20160406. Publication Type: journal article. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Psychiatry/Psychology. NLM UID: 0376505. 
SP  - 567
EP  - 574
JO  - Psychosomatic Medicine
JF  - Psychosomatic Medicine
JA  - PSYCHOSOM MED
VL  - 77
IS  - 5
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - Background: Patients with unexplained chest pain are commonly revisiting an emergency department with various symptoms, but comprehensive long-term studies are lacking.Methods: A total of 150 young adults (aged 18-40 years) with unexplained chest pain who presented at an emergency unit for 16 weeks in mid-1980s were included in a prospective cohort study. An age- and sex-matched control group was randomly selected from the same area. Data were retrieved from registers that recorded death, income, education, country of birth, diagnoses, hospitalizations, outpatient visits, and medications dispensed.Results: Patients with unexplained acute chest pain had lower levels of education and income and were more often immigrants. Long-term mortality rates did not differ between cases (4%) and controls (5%) during 25 years of follow-up, nor were there differences in diagnosis of ischemic heart disease. Patients with unexplained acute chest pain had more outpatient visits (median, 5 versus 2; p < .0001) and had more often been hospitalized (61.6% ever versus 41.8%; p < .001) during the follow-up period. Several disorders were more common among patients 20 to 25 years later, including atrial fibrillation, esophageal/gastric disorders, chest pain, palpitations, abdominal discomfort, musculoskeletal symptoms, sleeping disturbance, and stress reactions (p values < .05). More patients had been given antihypertensives, anticoagulants, antidepressants, analgesics, and hypnotics/tranquilizers (p values < .05).Conclusions: Young patients admitted to the emergency department with unexplained acute chest pain showed no increased risk of mortality or ischemic heart disease during 25 years of follow-up, but they had higher incidence of a wide range of disorders and used more medications. Early identification and preventive interventions may improve health outcomes in these patients.
SN  - 0033-3174
U2  - PMID: 25984822.
DO  - 10.1097/PSY.0000000000000188
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 113211209
T1  - Using new non-invasive quick method to detect Borrelia Burgdorferi (B.B.) infection from specific parts of the heart in "seemingly normal" ECGs, and from the ECGs of Atrial Fibrillation (AF), a majority of AF ECGs are found to have: 1) Significant B.B. infection, 2) Markedly increased ANP, 3) Increased Cardiac Troponin I & 4) Markedly reduced Taurine. These 4 factors were mainly localized at infected areas of the SA node area, R-&L- Atria & pulmonary veins at the L-atrium.
AU  - Yoshiaki Omura
AU  - Lu, Dominic
AU  - Jones, Marilyn K.
AU  - Nihrane, Abdallah
AU  - Duvvi, Harsha
AU  - Yapor, Dario
AU  - Yasuhiro Shimotsuura
AU  - Motomu Ohki
Y1  - 2015/12/15/
N1  - Accession Number: 113211209. Language: English. Entry Date: 20160224. Revision Date: 20160224. Publication Type: Article. Journal Subset: Alternative/Complementary Therapies; Peer Reviewed; USA. NLM UID: 7610364. 
KW  - Borrelia Infections
KW  - Electrocardiography
KW  - Atrial Fibrillation
KW  - Troponin
KW  - Lyme Disease
KW  - Acupuncture
KW  - Smartphone
KW  - Microscopy
KW  - Doxycycline -- Administration and Dosage
KW  - Human
SP  - 297
EP  - 333
JO  - Acupuncture & Electro-Therapeutics Research
JF  - Acupuncture & Electro-Therapeutics Research
JA  - ACUPUNCTURE ELECTRO THER RES
VL  - 40
IS  - 4
CY  - Putnam Valley, New York
PB  - Cognizant Communication Corporation
SN  - 0360-1293
AD  - Adjunct Prof., Dept. of Family & Community Medicine, New York Medical College
AD  - Director of Medical Research, Heart Disease Research Foundation
AD  - President, International College of Acupuncture & Electro-Therapeutics
AD  - Acupuncture & Electro-Therapeutics Research, International Journal of Integrated Medicine
AD  - Clinical Prof, of Oral Medicine, University of Pennsylvania
AD  - President, American Society for the Advancement of anesthesia and sedation
AD  - Visiting Prof, of Holistic Dentistry, International College of Acupuncture & Electrotherapeutics
AD  - Visiting Associate Prof, of Holistic Dentistry, International College of Acupuncture & Electrotherapeutics
AD  - Director, Holistic Dental Center of Houston
AD  - Visiting Associate Prof, of Integrative Medicine, International College of Acupuncture & Electro-Therapeutics
AD  - Clinical Assistant Prof., Dept. of Family & Community Medicine and Neurologist, New York Medical College
AD  - Visiting assistant professor of Holistic Dentistry, International College of Acupuncture & Electrotherapeutics
AD  - President, Japan Bi-Digital O-Ring Test Association
AD  - Visiting Prof, of Integrative Medicine, International College of Acupuncture & Electro-Therapeutics
AD  - Executive Director ORT Life Science Research Institute, Kurume City, Japan
AD  - ORT Life Science Research Institute, Kurume City, Japan
DO  - 10.3727/036012916X14533115160606
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107968364
T1  - Value of Yoga Training in Paroxysmal Atrial Fibrillation.
AU  - DiMarco, John P.
Y1  - 2013/07/29/
N1  - Accession Number: 107968364. Language: English. Entry Date: 20130830. Revision Date: 20150712. Publication Type: Journal Article; abstract; commentary. Original Study: Lakkireddy D, et al. Effect of yoga on arrhythmia burden, anxiety, depression, and quality of life in paroxysmal atrial fibrillation: The YOGA My Heart study. JAm Coll Cardiol 2013; 61: 1177-1182. Journal Subset: Biomedical; USA. Special Interest: Critical Care; Gerontologic Care; Sports Medicine. NLM UID: 8003602. 
KW  - Atrial Fibrillation -- Prevention and Control
KW  - Yoga -- Utilization
KW  - Anxiety -- Prevention and Control
KW  - Depression -- Prevention and Control
SP  - 109
EP  - 110
JO  - Internal Medicine Alert
JF  - Internal Medicine Alert
JA  - INTERN MED ALERT
VL  - 35
IS  - 14
CY  - Atlanta, Georgia
PB  - AHC Media LLC
SN  - 0195-315X
AD  - Professor of Medicine, Division of Cardiology, University of Virginia, Charlottesville
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 87374228
T1  - Value of Yoga Training in Paroxysmal Atrial Fibrillation.
AU  - Dimarco, John P.
Y1  - 2013/05//
N1  - Accession Number: 87374228. Language: English. Entry Date: 20130507. Revision Date: 20130508. Publication Type: Article. Original Study: Lakkireddy Dhanunjaya, Atkins Donita, Pillarisetti Jayasree, Ryschon Kay, Bommana Sudharani, Drisko Jeanne, et al. Effect of Yoga on Arrhythmia Burden, Anxiety, Depression, and Quality of Life in Paroxysmal Atrial Fibrillation: The YOGA My Heart Study. (J AM COLL CARDIOL) Mar2013; 61 (11): 1177-1182. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9880022. 
KW  - Yoga -- Methods
KW  - Atrial Fibrillation -- Therapy
KW  - Quality of Life
KW  - Anxiety
KW  - Depression
KW  - Treatment Outcomes
SP  - 39
EP  - 40
JO  - Clinical Cardiology Alert
JF  - Clinical Cardiology Alert
JA  - CLIN CARDIOL ALERT
VL  - 32
IS  - 5
CY  - Atlanta, Georgia
PB  - AHC Media LLC
SN  - 0741-4218
AD  - Professor of Medicine, Division of Cardiology, University of Virginia, Charlottesville
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104281025
T1  - Value of Yoga Training in Paroxysmal Atrial Fibrillation.
AU  - DiMarco, John P.
Y1  - 2013/05//
N1  - Accession Number: 104281025. Language: English. Entry Date: 20130507. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9880022. 
KW  - Yoga -- Methods
KW  - Atrial Fibrillation -- Therapy
KW  - Quality of Life
KW  - Anxiety
KW  - Depression
KW  - Treatment Outcomes
SP  - 39
EP  - 40
JO  - Clinical Cardiology Alert
JF  - Clinical Cardiology Alert
JA  - CLIN CARDIOL ALERT
VL  - 32
IS  - 5
CY  - Atlanta, Georgia
PB  - AHC Media LLC
SN  - 0741-4218
AD  - Professor of Medicine, Division of Cardiology, University of Virginia, Charlottesville
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 110940484
T1  - Visualisation during ablation of atrial fibrillation – stimulating the patient’s own resources: Patients’ experiences in relation to pain and anxiety during an intervention of visualisation.
AU  - Nørgaard, Marianne W.
AU  - Pedersen, Preben U.
AU  - Bjerrum, Merete
Y1  - 2015/12//
N1  - Accession Number: 110940484. Language: English. Entry Date: 20160104. Revision Date: 20160104. Publication Type: Article. Journal Subset: Continental Europe; Europe; Nursing; Peer Reviewed. Special Interest: Pain and Pain Management; Psychiatry/Psychology. NLM UID: 101128793. 
KW  - Atrial Fibrillation -- Therapy
KW  - Catheter Ablation -- Adverse Effects
KW  - Treatment Related Pain -- Therapy
KW  - Anxiety -- Therapy
KW  - Guided Imagery
KW  - Hypnosis
KW  - Human
KW  - Qualitative Studies
KW  - Content Analysis
KW  - Semi-Structured Interview
KW  - Denmark
KW  - Female
KW  - Male
KW  - Adult
KW  - Middle Age
KW  - Aged
KW  - Interview Guides
KW  - Cardiovascular Nursing
KW  - Perception
KW  - Patient Attitudes
KW  - Analgesia
KW  - Patient Satisfaction
KW  - Coping
SP  - 552
EP  - 559
JO  - European Journal of Cardiovascular Nursing
JF  - European Journal of Cardiovascular Nursing
JA  - EUR J CARDIOVASC NURS
VL  - 14
IS  - 6
PB  - Sage Publications, Ltd.
SN  - 1474-5151
AD  - Cardiac Cath Lab. Cardiology Clinic, Copenhagen University Hospital, Rigshospitalet, Denmark
AD  - Department of Health Science and Technology, The Faculty of Medicine, Aalborg University, Denmark
AD  - Department of Public Health - Department of Science in Nursing, Aarhus University, Denmark
DO  - 10.1177/1474515114548643
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103929285
T1  - VISUALISATION EASES PROCEDURAL PAIN.
Y1  - 2014/04/16/
N1  - Accession Number: 103929285. Language: English. Entry Date: 20140418. Revision Date: 20150710. Publication Type: Journal Article; brief item. Journal Subset: Double Blind Peer Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 9012906. 
KW  - Treatment Related Pain -- Therapy
KW  - Guided Imagery
KW  - Atrial Fibrillation -- Surgery
KW  - Catheter Ablation -- Adverse Effects
SP  - 11
EP  - 11
JO  - Nursing Standard
JF  - Nursing Standard
JA  - NURS STAND
VL  - 28
IS  - 33
PB  - RCNi
AB  - Nurses who guided cardiovascular patients into a trance during an invasive procedure found the technique lessened pain, according to a clinical study.
SN  - 0029-6570
U2  - PMID: 24734799.
DO  - 10.7748/ns2014.04.28.33.11.s10
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104068187
T1  - Visualization and Attentive Behavior for Pain Reduction during Radiofrequency Ablation of Atrial Fibrillation.
AU  - NØRgaard, Marianne W.
AU  - Werner, Anette
AU  - Abrahamsen, Randi
AU  - Larsen, Birgitte
AU  - Darmer, Mette Rosendal
AU  - Pedersen, Preben U.
Y1  - 2013/02//
N1  - Accession Number: 104068187. Language: English. Entry Date: 20140430. Revision Date: 20150710. Publication Type: Journal Article; clinical trial; research; tables/charts. Journal Subset: Allied Health; Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Instrumentation: Symptom Checklist 92 (SCL 92) [Danish]; Mini-Mental Status Examination (MMSE) (Folstein et al). Grant Information: This study was supported in part by grants from The Heartcentre, Rigshospitalet, Copenhagen Denmark, and from the Danish Nursing Research Fund.. NLM UID: 7803944. 
KW  - Atrial Fibrillation -- Surgery
KW  - Catheter Ablation -- Adverse Effects
KW  - Postoperative Pain -- Prevention and Control
KW  - Anxiety -- Prevention and Control
KW  - Guided Imagery
KW  - Cognitive Therapy -- Methods
KW  - Human
KW  - Catheter Ablation -- Methods
KW  - Postoperative Pain -- Etiology
KW  - Anxiety -- Etiology
KW  - Clinical Trials
KW  - Descriptive Statistics
KW  - Treatment Outcomes
KW  - Academic Medical Centers
KW  - Checklists
KW  - Data Analysis Software
KW  - Unpaired T-Tests
KW  - Mann-Whitney U Test
KW  - Fisher's Exact Test
KW  - Chi Square Test
KW  - Adult
KW  - Middle Age
KW  - Aged
KW  - Male
KW  - Female
KW  - Denmark
KW  - Funding Source
SP  - 203
EP  - 213
JO  - Pacing & Clinical Electrophysiology
JF  - Pacing & Clinical Electrophysiology
JA  - PACING CLIN ELECTROPHYSIOL
VL  - 36
IS  - 2
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Background Radiofrequency (RF) ablation of atrial fibrillation (AF) can be accompanied by pain and anxiety when light conscious sedation is used. We sought to determine how visualization and structured attentive behavior during ablation of AF could reduce pain intensity, spontaneously expressed pain, the amount of analgesics, anxiety, and adverse events. Methods A clinical controlled study with 71 patients in a control group (CG), receiving conventional care and treatment, and 76 patients in an intervention group (IG), receiving relaxation and visualization, combined with a structured attentive behavior from staff. Results There was no difference between CG and IG in perception of pain intensity at 15-minute intervals; mean pain intensity: CG (0.00-2.90), IG (0.12-2.57), (NS), but patients spontaneously expressed pain less numbers of time outside fixed intervals in the IG: 1.4 ± 1.2 times (mean ± standard deviation [SD]) compared to CG: 2.8 ± 1.8 (P < 0.01). There was a statistically significant difference between the amount of analgesics (Fentanyl) used in the two groups: CG: 292.3 ± 107μg (mean ± SD) and IG: 220.7 ± 93μg (P < 0.0001). No effect was observed in perception of anxiety, mean anxiety: CG (0.10-1.84), IG (0.9-2.03)(NS), and the number of adverse events (P = 0.241). Conclusion Visualization and structured attentive behavior was shown to reduce the amount of analgesics during the RF ablation of AF. There was no difference in perception of pain intensity, but the patients spontaneously expressed pain significantly less numbers of times outside the scheduled measurements. There was no reduction in anxiety and numbers of adverse events.
SN  - 0147-8389
AD  - Cardiac Catheterization Laboratory, Cardiology Clinic B, the Heart Centre, University of Copenhagen
AD  - Department of Gynecology and Obstetrics, Aarhus University Hospital
AD  - Department of Clinical Oral Physiology, School of Dentistry, Aarhus University
AD  - Department of Nursing Science, Institute of Public Health, Aarhus University
U2  - PMID: 23127191.
DO  - 10.1111/pace.12032
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104068187&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106439212
T1  - Warfarin pharmacology, clinical management, and evaluation of hemorrhagic risk for the elderly.
AU  - Jacobs LG
Y1  - 2006/02//2006 Feb
N1  - Accession Number: 106439212. Language: English. Entry Date: 20060512. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 8603766. 
KW  - Anticoagulants -- Pharmacodynamics
KW  - Cerebral Hemorrhage -- Chemically Induced
KW  - Gastrointestinal Hemorrhage -- Chemically Induced
KW  - Warfarin -- Pharmacodynamics
KW  - Age Factors
KW  - Aged
KW  - Aged, 80 and Over
KW  - Anticoagulants -- Adverse Effects
KW  - Anticoagulants -- Therapeutic Use
KW  - Cerebral Hemorrhage -- Prevention and Control
KW  - Dose-Response Relationship, Drug
KW  - Drug Administration Schedule
KW  - Female
KW  - Gastrointestinal Hemorrhage -- Prevention and Control
KW  - Geriatric Assessment
KW  - Male
KW  - Monitoring, Physiologic
KW  - Prospective Studies
KW  - Prothrombin Time
KW  - Risk Assessment
KW  - Treatment Outcomes
KW  - Warfarin -- Adverse Effects
KW  - Warfarin -- Therapeutic Use
SP  - 17
EP  - 32
JO  - Clinics in Geriatric Medicine
JF  - Clinics in Geriatric Medicine
JA  - CLIN GERIATR MED
VL  - 22
IS  - 1
CY  - Philadelphia, Pennsylvania
PB  - W B Saunders
AB  - Elderly patients as a group may present more of a challenge in managing warfarin therapy because of alterations in pharmacokinetics from other medications, diet, and disease; pharmacodynamic changes; increased risk for hemorrhage; and difficulty in monitoring. The elderly, however, may derive the most benefit from warfarin therapy for certain indications, such as the prevention of stroke in atrial fibrillation or recurrent events following deep venous thrombosis. Warfarin can be managed as effectively as in other populations with careful attention to these issues. Copyright © 2006 by Elsevier Science (USA).
SN  - 0749-0690
AD  - Division of Geriatrics, Albert Einstein College of Medicine, Montefiore Medical Center, 111 East 210th St, Bronx, NY 10467; lajacobs@montefiore.org
U2  - PMID: 16377465.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106015131
T1  - Web top 10.
Y1  - 2006/11//
N1  - Accession Number: 106015131. Language: English. Entry Date: 20071207. Revision Date: 20150711. Publication Type: Journal Article; brief item. Journal Subset: Biomedical; Blind Peer Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. NLM UID: 9602087. 
KW  - Angioplasty, Transluminal, Percutaneous Coronary -- Adverse Effects
KW  - Aortic Aneurysm, Thoracic -- Surgery
KW  - Atrial Fibrillation -- Therapy
KW  - Cardiovascular Diseases -- Prevention and Control
KW  - Endocarditis, Bacterial
KW  - Exercise
KW  - Myocardial Infarction -- Etiology
KW  - Tetralogy of Fallot
KW  - Troponin -- Diagnostic Use
KW  - Ventricular Dysfunction -- Therapy
SP  - 1691
EP  - 1691
JO  - Heart
JF  - Heart
JA  - HEART
VL  - 92
IS  - 11
PB  - BMJ Publishing Group
SN  - 1355-6037
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104406659
T1  - What's new.
Y1  - 2012/09//
N1  - Accession Number: 104406659. Language: English. Entry Date: 20121228. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Consumer Health; Peer Reviewed; USA. Special Interest: Consumer Health; Nutrition; Women's Health. NLM UID: 9423147. 
KW  - Age Factors
KW  - Atrial Fibrillation
KW  - Breast Neoplasms -- Prevention and Control
KW  - Diet
KW  - Exercise
KW  - Female
KW  - Fruit
KW  - Health Behavior
KW  - Longevity
KW  - Mortality
KW  - Physical Fitness
KW  - Smoking Cessation
KW  - Stroke -- Risk Factors
KW  - Vegetables
KW  - Women's Health
SP  - 1
EP  - 8
JO  - Harvard Women's Health Watch
JF  - Harvard Women's Health Watch
JA  - HARV WOMENS HEALTH WATCH
VL  - 20
IS  - 1
CY  - Stamford, Connecticut
PB  - Harvard Health Publications
SN  - 1070-910X
U2  - PMID: 23035325.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106495204
T1  - Work related physical activity and risk of a hospital discharge diagnosis of atrial fibrillation or flutter: the Danish Diet, Cancer, and Health study.
AU  - Frost L
AU  - Frost P
AU  - Vestergaard P
Y1  - 2005/01//
N1  - Accession Number: 106495204. Language: English. Entry Date: 20050805. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Grant Information: Danish Medical Research Council (grant number 22-02-0582). NLM UID: 9422759. 
KW  - Atrial Fibrillation -- Etiology
KW  - Atrial Flutter -- Etiology
KW  - Occupational Diseases -- Etiology
KW  - Cox Proportional Hazards Model
KW  - Denmark
KW  - Epidemiological Research
KW  - Exertion
KW  - Female
KW  - Funding Source
KW  - Incidence
KW  - Linear Regression
KW  - Male
KW  - Middle Age
KW  - Occupational Diseases -- Epidemiology
KW  - Prospective Studies
KW  - Registries, Disease
KW  - Risk Assessment -- Methods
KW  - Workload
KW  - Human
SP  - 49
EP  - 53
JO  - Occupational & Environmental Medicine
JF  - Occupational & Environmental Medicine
JA  - OCCUP ENVIRON MED
VL  - 62
IS  - 1
PB  - BMJ Publishing Group
AB  - BACKGROUND AND AIMS: Excessive sporting activities have been associated with risk of atrial fibrillation. To study if work related physical activity also confers risk of atrial fibrillation or flutter, the association between work related physical strain and the risk of a hospital discharge diagnosis (inpatient as well as outpatient) of atrial fibrillation or flutter was examined. METHODS: A population based prospective cohort study was conducted from December 1993 to December 2001 among 19 593 men and 18,807 women with a mean age at baseline of 56 years (range 50-65 years) in the Danish Diet, Cancer, and Health Study. The physical strain during working hours was categorised as sedentary, light, or heavy, and analysed using proportional hazard models. Subjects were followed up in the Danish National Registry of Patients and in the Danish Civil Registration System. RESULTS: During follow up (mean 5.7 years) a hospital discharge diagnosis of atrial fibrillation or flutter occurred in 305 men and 113 women. When using the risk of atrial fibrillation or flutter associated with sedentary work at a sitting position as a reference, no excess risk (unadjusted as well as adjusted) was found of atrial fibrillation or flutter associated with sedentary work in a standing position, light workload, or heavy workload in men or women. CONCLUSION: No evidence was found of an association between physical activities during working hours and risk of a hospital discharge diagnosis of atrial fibrillation or flutter for men and women in the age group of 50-65 years.
SN  - 1351-0711
AD  - Department of Cardiology A, Aarhus University Hospital, DK-8000 Aarhus C, Denmark; rlg041fr@as.aaa.dk
U2  - PMID: 15613608.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106744307
T1  - Ximelagatran: a new era in oral anticoagulation.
AU  - McCall KL
AU  - MacLaughlin EJ
Y1  - 2003/07//2003 Jul-Aug
N1  - Accession Number: 106744307. Language: English. Entry Date: 20040611. Revision Date: 20150711. Publication Type: Journal Article; CEU; exam questions; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Double Blind Peer Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 8504643. 
KW  - Fibrinolytic Agents -- Therapeutic Use
KW  - Thromboembolism -- Prevention and Control
KW  - Venous Thrombosis -- Prevention and Control
KW  - Animal Studies
KW  - Atrial Fibrillation -- Complications
KW  - Atrial Fibrillation -- Drug Therapy
KW  - Stroke -- Etiology
KW  - Stroke -- Prevention and Control
KW  - Clinical Trials
KW  - Education, Continuing (Credit)
KW  - Fibrinolytic Agents -- Pharmacodynamics
KW  - Fibrinolytic Agents -- Pharmacokinetics
KW  - Hemorrhage -- Chemically Induced
KW  - Hemorrhage -- Epidemiology
KW  - Thrombin -- Antagonists and Inhibitors
KW  - Thromboembolism -- Drug Therapy
KW  - Venous Thrombosis -- Drug Therapy
SP  - 222
EP  - 258
JO  - Journal of Pharmacy Technology
JF  - Journal of Pharmacy Technology
JA  - J PHARM TECHNOL
VL  - 19
IS  - 4
CY  - Thousand Oaks, California
PB  - Sage Publications Inc.
AB  - OBJECTIVE: To review the pharmacology, pharmacokinetics, and clinical trials of the oral direct thrombin inhibitor ximelagatran.DATA SOURCES: All primary articles involving ximelagatran or its active form, melagatran, and indexed on MEDLINE or International Pharmaceutical Abstracts databases (1966-December 2002) were evaluated. Recent ximelagatran and melagatran abstracts were also obtained online from the American Society of Hematology at www.hematology.org/meeting/abstracts.cfm (2001 and 2002).DATA SYNTHESIS: Ximelagatran is an orally bioavailable prodrug of melagatran that directly blocks unbound thrombin and fibrin-bound thrombin. Ximelagatran displays predictable pharmacodynamic and pharmacokinetic properties with a linear dose-response relationship and low interpatient variability. These parameters allow fixed dosing of ximelagatran without routine coagulation monitoring. Ximelagatran has yet to be approved by the FDA; however, several major clinical trials have been completed. These clinical trials have revealed that an easier-to-manage ximelagatran regimen is at least as effective and has a similar safety profile as conventional therapy for prevention of venous thromboembolism (VTE). The results of studies with ximelagatran for treatment of VTE and prevention of thrombosis associated with atrial fibrillation are promising, but need further investigation.CONCLUSIONS: Ximelagatran possesses several advantages over warfarin including fixed dosing and the lack of coagulation monitoring, the absence of known diet or drug interactions, and a faster onset of action. Ximelagatran appears to be at least as effective as warfarin for prevention of VTE. Further research is needed with ximelagatran in the treatment of VTE and atrial fibrillation.
SN  - 8755-1225
AD  - School of Pharmacy, Texas Tech University Health Sciences Center, 1300 Coulter Dr, Amarillo, TX 79106-1712; kenneth@ama.ttuhsc.edu
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104187443
T1  - Yoga and acupressure help control blood pressure in people with atrial fibrillation.
Y1  - 2013/07//
N1  - Accession Number: 104187443. Language: English. Entry Date: 20130708. Revision Date: 20150711. Publication Type: Journal Article; brief item. Journal Subset: Consumer Health; Peer Reviewed; USA. Special Interest: Consumer Health; Women's Health. NLM UID: 9423147. 
KW  - Yoga
KW  - Acupressure
KW  - Atrial Fibrillation
KW  - Blood Pressure
SP  - 8
EP  - 8
JO  - Harvard Women's Health Watch
JF  - Harvard Women's Health Watch
JA  - HARV WOMENS HEALTH WATCH
VL  - 20
IS  - 11
CY  - Stamford, Connecticut
PB  - Harvard Health Publications
SN  - 1070-910X
U2  - PMID: 24818280.
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DP  - EBSCOhost
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ER  -