TY  - JOUR
ID  - 128228267
T1  - Delayed post mastectomy breast reconstructions with allogeneic acellular dermal matrix prepared by a new decellularizationmethod.
AU  - Bohac, Martin
AU  - Varga, Ivan
AU  - Polak, Stefan
AU  - Dragunova, Jana
AU  - Fedeles, Jozef
AU  - Koller, Jan
AU  - Fedeles, Jozef Sr.
Y1  - 2018/03//
N1  - Accession Number: 128228267. Language: English. Entry Date: In Process. Revision Date: 20180302. Publication Type: journal article. Journal Subset: Biomedical; Continental Europe; Europe. Grant Information: 1/0297/14//Slovak Ministry of Education. VEGA/. NLM UID: 100965121. 
SP  - 61
EP  - 68
JO  - Cell & Tissue Banking
JF  - Cell & Tissue Banking
JA  - CELL TISSUE BANKING
VL  - 19
IS  - 1
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
AB  - Acellular dermal matrix (ADM) is a tissue graft of allogeneic origin from post-mortem tissue donors prepared by an innovative decellularization process. The newly developed non-toxic and low cost decellularization process of cadaver origin dermis included ADM in breast reconstruction procedures proved to help coverage of the lower-pole of breast expanders or implants. As the results have shown, it did help to eliminate autologous dermis donor site morbidity along with shortening the operation time by avoiding elevation of additional muscle or fascia during the operation. Main aims of this article include histology evaluation of allogeneic acellular dermal matrix prepared by a new decellularization method and presentation of clinical results of its use. A total of 22 patients underwent 26 ADM based breast reconstructions. The mean patient's follow up was 12.6 months. Average total size of ADM used for one breast was 273 cm2. Post-operative complications occurred in 3 patients including one expander infection, one expander extrusion and one expander pocket disfiguration. Microscopic analysis of tissue samples has confirmed incorporation of the acellular dermal matrices into the surrounding connective tissue without any noticeable immune reaction. In a majority of the ADM samples we found pseudocapsullar formation on implant side of samples without acute or chronic inflammatory cells. The use of ADM prepared by new preparation method in expansive post mastectomy breast reconstruction was associated by a relatively low complication rate resulting in good outcomes.
SN  - 1389-9333
AD  - Department of Plastic Surgery, Faculty of Medicine, University Hospital Bratislava, Comenius University in Bratislava, Ruzinovska 6, 826 06, Bratislava, Slovakia
AD  - Regenmed Ltd., Medena 29, 811 02, Bratislava, Slovakia
AD  - Faculty of Medicine, Institute of Histology and Embryology, Comenius University in Bratislava, Sasinkova 4, 811 08, Bratislava, Slovakia
AD  - Department of Burns and Reconstructive Surgery, Faculty of Medicine, University Hospital Bratislava, Comenius University in Bratislava, Bratislava, Slovakia
U2  - PMID: 28812172.
DO  - 10.1007/s10561-017-9655-0
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 124470421
T1  - Efeito imediato da técnica de mobilização nas interfaces fasciais profundas da região peitoral em pacientes submetidas à mastectomia.
AU  - de Abreu Prado Junior, José Roberto
AU  - Inocêncio, Kelly Rosane
AU  - Custódio da Silva, André
AU  - dos Santos Almeida, Marcia
AU  - Bergmann, Anke
AU  - Guilherme Silva, Júlio
Y1  - 2017/03//
N1  - Accession Number: 124470421. Language: Portuguese. Entry Date: 20180410. Revision Date: 20180410. Publication Type: Article; pictorial; research; tables/charts. Journal Subset: Allied Health; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Mexico & Central/South America; Peer Reviewed. NLM UID: 101137551. 
KW  - Myofascial Release
KW  - Pectoralis Muscles
KW  - Mastectomy
KW  - Pain -- Prevention and Control
KW  - Range of Motion
KW  - Human
KW  - Female
KW  - Intercostal Muscles
KW  - Flexion
KW  - Goniometry
KW  - Visual Analog Scaling
KW  - T-Tests
KW  - Shoulder -- Physiopathology
KW  - Women's Health
SP  - 180
EP  - 188
JO  - Fisioterapia Brasil
JF  - Fisioterapia Brasil
JA  - FISIOTER BRASIL
VL  - 18
IS  - 2
PB  - Atlantica Editora
AB  - Introduction: Breast cancer has high incidence, morbidity and mortality and its treatment can result in different complication with physical, emotional and social repercussions. In musculoeskeletal rehabilitation, prevention and postoperative treatment of complications have been highlighted, especially in scapular girdle and shoulder. Myofascial technique in treatment of the shoulder dysfunctions can benefit the reestablishment in upper limb function. Objective: The aim of this study was to evaluate the effect of deep myofascial technique in pain and range of motion (ROM), in women post-surgery breast cancer. Methods: In this study pre and post intervention, 28 subjects with intercostobrachialgia and decreasing ROM were analyzed and submitted to only one intervention during 10 seconds in deep pectoral fascia. Arm flexion was evaluated using photogoniometric technique and for pain Visual Analogical Scale (VAS). ROM data was analyzed by Test T student with level of significance 95% (p < 0.05). Results: The mean of ROM pre-intervention was 109,9o and post 146,08o (p = 0.001) and ROM percentage gain 32% (± 24.26). There was 60% of pain percentage reduction between pre and post intervention. The results revealed increase of ROM and decrease of pain in shoulders dysfunction due to mastectomy. Conclusion: Further investigations should be performed to evaluate the results of deep myofascial technique in different shoulders movements, as well as to compare with other therapeutic exercise strategies to treat shoulder dysfunction of mastectomized women.
AB  - Introdução: O câncer de mama apresenta alta incidência, morbidade e mortalidade. Seu tratamento pode acarretar diferentes complicações, com repercussões físicas, emocionais e sociais. No âmbito da reabilitação das alterações musculoesqueléticas, condutas de prevenção e tratamento das complicações pós-operatórias têm merecido atenção especial, dentre elas podemos destacar as disfunções da cintura escapular e ombro. As abordagens terapêuticas miofasciais no tratamento das disfunções do ombro pós-operatórias podem favorecer o restabelecimento da função do membro superior. Objetivo: Analisar o efeito imediato da técnica de mobilização fascial profundas na dor e no arco de movimento (ADM) em mulheres submetidas à mastectomia. Métodos: Neste estudo pré e pós-intervenção em 28 mulheres mastectomizadas, com intercostobraquialgia e bloqueio de ADM para a flexão do braço, as pacientes foram submetidas à técnica de mobilização fascial profunda da região peitoral, em uma única intervenção de 10 segundos. A flexão do braço foi mensurada por meio da fotogoniometria e a dor avaliada pela escala analógica visual (EVA). Os dados de ADM foram analisados através do Teste T student com um nível de significância de 95% (p < 0,05). Resultados: A média da ADM pré-intervenção foi de 109,99o e pós de 146,08o (p = 0,001) com um percentual médio de melhora de 32% (± 24,26). A dor teve um percentual de redução pré e pós-intervenção de 60% (± 24,26). Os dados apontaram para um ganho de ADM e diminuição da dor nas disfunções do ombro decorrente da mastectomia. Conclusão: Novas investigações devem ser realizadas para avaliar os resultados da técnica de liberação miofascial profunda em outros movimentos do ombro, como também comparar com as demais estratégias cinesioterapêuticas no tratamento das disfunções do ombro em mulheres mastectomizadas.
SN  - 1518-9740
AD  - Centro Universitário Augusto Motta (UNISUAM), Rio de Janeiro/RJ
AD  - Fisioterapeuta-Chefe do Serviço de Fisioterapia Oncológica do Centro Municipal de Reabilitação Engenho de Dentro, Rio de Janeiro/RJ
AD  - Prof. Assistente do Curso de Fisioterapia da Universidade Veiga de Almeida, Prof. Colaborador do Laboratório de Biomecânica da Universidade Estadual do Rio de Janeiro (UERJ)
AD  - Especialista em Fisioterapia Traumato-Ortopédica -- Universidade Gama Filho, Colaboradora do Laboratório de Análise de Movimento Humano -- UNISUAM / RJ, Programa de Iniciação Científica -- UNISUAM / RJ
AD  - Epidemiologista, Instituto Nacional de Câncer (INCA) -- RJ
AD  - Prof. do Programa de Mestrado e Doutorado em Ciências da Reabilitação do UNISUAM, Prof. Adjunto do Departamento de Fisioterapia -- Faculdade de Medicina, Universidade Federal do Rio de Janeiro (UFRJ), Coordenador do Grupo de Pesquisa em Terapias Manuais (GETEM/UFRJ) Marcia dos Santos Almeida
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 119458168
T1  - Use of Acellular Dermal Matrix versus Latissimus Dorsi Flap for Breast Reconstruction: Clinical and Patient-Reported Outcomes.
AU  - Youssef, Mina M. G.
AU  - Pucher, Philip H.
AU  - Kennedy, Katy
AU  - Osborne, Caroline
AU  - Graja, Tomasz
Y1  - 2016/11//Nov/Dec2016
N1  - Accession Number: 119458168. Language: English. Entry Date: 20161118. Revision Date: 20171101. Publication Type: Article; letter; questionnaire/scale; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Peer Reviewed; USA. Instrumentation: Modified EORTC Patient Satisfaction Questionnaire (EORTC IN-PATSAT32). NLM UID: 9505539. 
KW  - Breast Reconstruction -- Methods
KW  - Patient Satisfaction
KW  - Treatment Outcomes
KW  - Latissimus Dorsi Muscles -- Surgery
KW  - Surgical Flaps
KW  - Human
KW  - Female
KW  - Inpatients
KW  - Academic Medical Centers -- United Kingdom
KW  - United Kingdom
KW  - Questionnaires
KW  - Descriptive Statistics
KW  - Data Analysis Software
KW  - P-Value
KW  - Mann-Whitney U Test
KW  - Comparative Studies
KW  - Postoperative Complications
KW  - Adult
KW  - Middle Age
KW  - Aged
SP  - 702
EP  - 704
JO  - Breast Journal
JF  - Breast Journal
JA  - BREAST J
VL  - 22
IS  - 6
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - The article focuses on a research related to clinical and patient-reported outcomes in the use of acellular dermal matrix versus latissimus dorsi flap for breast reconstruction. Topics discussed include comparing patient-reported and clinical outcomes for latissimus dorsi (LD) and acellular dermal matrix (ADM) reconstruction; recording patient demographics, operative time, and length of in-hospital stay, and importance of considering psychological needs and expectations of patients.
SN  - 1075-122X
AD  - Department of Surgery, Dorset County Hospital
AD  - National Cancer Institute, Cairo University
AD  - Department of Surgery, Yeovil District Hospital
DO  - 10.1111/tbj.12664
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 121502353
T1  - Acellular dermal matrix reduces capsule formation in two-stage breast reconstruction.
AU  - Chopra, Karan
AU  - Buckingham, Bryan
AU  - Matthews, Jamil
AU  - Sabino, Jennifer
AU  - Tadisina, Kashyap K
AU  - Silverman, Ronald P
AU  - Goldberg, Nelson H
AU  - Slezak, Sheri
AU  - Singh, Devinder P
Y1  - 2017/04//
N1  - Accession Number: 121502353. Language: English. Entry Date: 20170321. Revision Date: 20180402. Publication Type: Article; pictorial; research; tables/charts. Journal Subset: Biomedical; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. NLM UID: 101230907. 
KW  - Breast Reconstruction
KW  - Breast Implants
KW  - Biopsy
KW  - Collagen
KW  - Human
KW  - Mastectomy
KW  - Pectoralis Muscles
KW  - Postoperative Complications
KW  - Tissue Expansion
KW  - Neutrophils
SP  - 414
EP  - 419
JO  - International Wound Journal
JF  - International Wound Journal
JA  - INT WOUND J
VL  - 14
IS  - 2
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Acellular dermal matrix ( ADM) is commonly employed to create an inferior pocket for the tissue expander in two-stage breast reconstruction. The authors sought to determine whether placement of ADM during the first stage of reconstruction decreases the amount of capsule formation at implant exchange. Patients who underwent mastectomy and tissue expander reconstruction were included in this study. Two biopsies were obtained at the time of implant exchange, one from the pocket adjacent to the ADM and the other from the area adjacent to the pectoralis muscle. Pathology analysis was performed on each sample. Ten patients underwent immediate breast reconstruction with Alloderm during the 3-month study period. Capsule thickness was significantly greater in the areas where the expander was in direct contact with the pectoralis muscle (782 ± 194 µm) compared to those in contact with human acellular dermal matrix ( hADM) (47·91 ± 110·82 µm; P < 0·05). Analysis of the sub-pectoral capsule demonstrated diffuse deposition of collagen, neutrophils, contractile myofibroblasts and synovia-like metaplasia, characteristic of a foreign body response. Conversely, within the inferior pocket where the hADM was in direct contact with the expander, we noted migration of host epithelial cells, fibroblasts, mesenchymal cells and angiogenesis, indicating host tissue regeneration. Acellular dermal matrix, when placed at the first stage of breast reconstruction, significantly reduces thickness and inflammatory character of the capsule in comparison to the patient's native tissue.
SN  - 1742-4801
AD  - Division of Plastic Surgery, University of Maryland School of Medicine
AD  - Department of Plastic & Reconstructive Surgery, The Johns Hopkins Hospital
AD  - Department of Plastic Surgery, Anne Arundel Medical Center
DO  - 10.1111/iwj.12620
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 125011202
T1  - Biological incorporation of human acellular dermal matrix used in Achilles tendon repair.
AU  - Bertasi, Giampietro
AU  - Cole, Windy
AU  - Samsell, Brian
AU  - Qin, Xiaofei
AU  - Moore, Mark
Y1  - 2017/09//
N1  - Accession Number: 125011202. Language: English. Entry Date: In Process. Revision Date: 20171209. Publication Type: journal article. Journal Subset: Biomedical; Continental Europe; Europe. NLM UID: 100965121. 
SP  - 403
EP  - 411
JO  - Cell & Tissue Banking
JF  - Cell & Tissue Banking
JA  - CELL TISSUE BANKING
VL  - 18
IS  - 3
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
AB  - Human acellular dermal matrices (ADMs) are used successfully in a variety of procedures, including sports medicine related, wound repair, and breast reconstructions, but the mechanism of repair is still not fully understood. An opportunity to explore this mechanism presented itself when a patient experienced a rerupture of the native tendon due to a fall that occurred 2 months after undergoing an Achilles tendon repair using Matracell treated ADM. The ADM was removed and an extensive histology analysis was performed on the tissue. Additionally, a literature review was conducted to determine the mechanism of ADM integration into the tendon structure and explore if differences in this mechanism exist for different types of human ADMS. The histology analysis demonstrated that the healing process during a tendon reconstruction procedure is similar to that of wound healing. Furthermore, the literature review showed that differences exist in the mechanism for integration among various human ADMs and that these differences may be due to variances in the methods and technologies that manufactures use to process human ADMs.
SN  - 1389-9333
AD  - University of Padua , Padua Italy
AD  - Robinson Wound Care Center , 1533 South Water Street Kent USA
AD  - LifeNet Health , 1864 Concert Drive Virginia Beach USA
U2  - PMID: 28455604.
DO  - 10.1007/s10561-017-9628-3
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 123852713
T1  - Implicações das cirurgias de câncer de mama nas atividades profissionais.
AU  - Dias, Mirella
AU  - Zomkowski, Kamilla
AU  - Silva Michels, Fernanda Alessandra
AU  - Flores Sperandio, Fabiana
Y1  - 2017/06//
N1  - Accession Number: 123852713. Language: Portuguese. Entry Date: In Process. Revision Date: 20170802. Publication Type: Article. Journal Subset: Allied Health. 
SP  - 325
EP  - 332
JO  - Brazilian Journal of Occupational Therapy / Cadernos Brasileiros de Terapia Ocupacional
JF  - Brazilian Journal of Occupational Therapy / Cadernos Brasileiros de Terapia Ocupacional
VL  - 25
IS  - 2
PB  - Cadernos de Terapia Ocupacional da UFSCar
AB  - Introduction: Breast cancer is responsible for 25% of all cancers and is the most prevalent in the female population. Due to treatment advances and early diagnoses, survival rates have improved, however this condition impacts work absenteeism due to the productive age of these women. The main factors responsible for work absenteeism are physical complications due to surgical treatment. Objective: The aim of this study is to investigate the effects of surgical breast cancer treatments on occupation, to characterize the degree of work absenteeism and to investigate the type of relation between surgical technique and absenteeism's main causes. Method: Cross-sectional study with 74 women diagnosed with breast cancer. A semi-structured interview was used to collect information regarding surgical and clinical aspects, sociodemographic data, work behavior and physical therapy treatments. The data was organized on Microsoft Excel and analyzed by frequency and chi-squared test. The significance level considered was p ≤ 0.05. Results: Breast cancer was most common on the left side (51%), Madden modified radical mastectomy was the most common (50%) and lymph node resection was present in 93.2% of cases. The most frequent post-surgery complications were pain, problems with scarring, sensitivity alterations, ROM limitation, lymphedema and seroma. Only 58% of women were treated with physical therapy and 60% withdrew from professional activities, 23% abandoned work, 26% changed their work role and 14% retired due to the disease. Conclusion: The present study suggests the existence of a direct relation between treatment and work absenteeism.
AB  - Introdução: O câncer de mama representa 25% de todos os tipos de câncer, sendo o de maior incidência na população feminina. Com o avanço dos tratamentos e diagnósticos precoces, as taxas de sobrevida têm aumentado e tal contexto reflete nos afastamentos laborais, tendo em vista que a maioria das mulheres se encontra em idade produtiva. Os principais motivos responsáveis pelos afastamentos do trabalho são as complicações físicas decorrentes do tratamento cirúrgico. Objetivo: Objetivou-se investigar as implicações cirúrgicas do tratamento do câncer de mama na atividade profissional, caracterizar o número de afastamentos laborais e investigar a relação entre o tipo de cirurgia nos afastamentos do trabalho e seus principais motivos. Método: Estudo transversal envolvendo 74 mulheres diagnosticadas com câncer de mama. Para a coleta dos dados, foi utilizada uma entrevista semiestruturada, que abordou as questões clínico-cirúrgicas, os dados sociodemográficos, o comportamento laboral e o tratamento fisioterapêutico. Os dados foram organizados no Microsoft Excel mediante frequências e o teste de qui-quadrado, sendo considerado p ≤ 0,05. Resultados: O lado esquerdo foi o mais acometido pela doença (51%), a cirurgia radical modificada do tipo Madden foi a mais comum (50%) e 93,2% submeteram-se à linfadenectomia axilar. As complicações operatórias mais frequentes foram dor, problemas cicatriciais, alteração da sensibilidade, limitação da ADM, linfedema e seroma. Apenas 58% delas fizeram fisioterapia e 60% afastaram-se das atividades profissionais, 23% abandonaram o trabalho, 26% modificaram as funções do trabalho e 14% se aposentaram por motivo de doença. Conclusão: Este estudo sugere a existência de uma relação direta do tratamento sobre os afastamentos laborais.
SN  - 2526-8910
AD  - Universidade Federal de Santa Catarina -- UFSC, Florianópolis, SC, Brasil
AD  - Universidade Estadual de Santa Catarina -- UDESC, Florianópolis, SC, Brasil.bUniversidade Estadual de Santa Catarina -- UDESC, Florianópolis, SC, Brasil
AD  - Universidade de São Paulo -- USP, São Paulo, SP, Brasil
DO  - 10.4322/0104-4931.ctoAO0792
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 121069020
T1  - Two-stage implant-based breast reconstruction compared with immediate one-stage implant-based breast reconstruction augmented with an acellular dermal matrix: an open-label, phase 4, multicentre, randomised, controlled trial.
AU  - Dikmans, Rieky E G
AU  - Negenborn, Vera L
AU  - Bouman, Mark-Bram
AU  - Winters, Hay A H
AU  - Twisk, Jos W R
AU  - Ruhé, P Quinten
AU  - Mureau, Marc A M
AU  - Smit, Jan Maerten
AU  - Tuinder, Stefania
AU  - Eltahir, Yassir
AU  - Posch, Nicole A
AU  - van Steveninck-Barends, Josephina M
AU  - Meesters-Caberg, Marleen A
AU  - van der Hulst, René R W J
AU  - Ritt, Marco J P F
AU  - Mullender, Margriet G
Y1  - 2017/02//
N1  - Accession Number: 121069020. Language: English. Entry Date: In Process. Revision Date: 20170614. Publication Type: journal article; clinical trial; research; randomized controlled trial. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice. Instrumentation: Longitudinal Interval Follow-Up Evaluation (LIFE); Ferrans and Powers Quality of Life Index. NLM UID: 100957246. 
KW  - Carcinoma, Lobular -- Surgery
KW  - Breast Reconstruction -- Methods
KW  - Breast Implants -- Methods
KW  - Adenocarcinoma -- Surgery
KW  - Breast Neoplasms -- Surgery
KW  - Dermis
KW  - Carcinoma, Ductal, Breast -- Surgery
KW  - Adenocarcinoma -- Pathology
KW  - Neoplasm Staging
KW  - Quality of Life
KW  - Netherlands
KW  - Reoperation
KW  - Postoperative Complications
KW  - Breast Neoplasms -- Pathology
KW  - Human
KW  - Study Design
KW  - Prospective Studies
KW  - Adult
KW  - Treatment Outcomes
KW  - Middle Age
KW  - Carcinoma, Ductal, Breast -- Pathology
KW  - Breast Implants
KW  - Carcinoma, Lobular -- Pathology
KW  - Female
KW  - Mastectomy -- Methods
KW  - Clinical Trials
KW  - Validation Studies
KW  - Comparative Studies
KW  - Evaluation Research
KW  - Multicenter Studies
KW  - Randomized Controlled Trials
KW  - Ferrans and Powers Quality of Life Index
SP  - 251
EP  - 258
JO  - Lancet Oncology
JF  - Lancet Oncology
JA  - LANCET ONCOL
VL  - 18
IS  - 2
CY  - New York, New York
PB  - Elsevier B.V.
AB  - Background: The evidence justifying the use of acellular dermal matrices (ADMs) in implant-based breast reconstruction (IBBR) is limited. We did a prospective randomised trial to compare the safety of IBBR with an ADM immediately after mastectomy with that of two-stage IBBR.Methods: We did an open-label, randomised, controlled trial in eight hospitals in the Netherlands. Eligible women were older than 18 years with breast carcinoma or a gene mutation linked with breast cancer who intended to undergo skin-sparing mastectomy and immediate IBBR. Randomisation was done electronically, stratified per centre and in blocks of ten to achieve roughly balanced groups. Women were assigned to undergo one-stage IBBR with ADM (Strattice, LifeCell, Branchburg, NJ, USA) or two-stage IBBR. The primary endpoint was quality of life and safety was assessed by the occurrence of adverse outcomes. Analyses were done per protocol with logistic regression and generalised estimating equations. This study is registered at Nederlands Trial Register, number NTR5446.Findings: 142 women were enrolled between April 14, 2013, and May 29, 2015, of whom 59 (91 breasts) in the one-stage IBBR with ADM group and 62 (92 breasts) in the two-stage IBBR group were included in analyses. One-stage IBBR with ADM was associated with significantly higher risk per breast of surgical complications (crude odds ratio 3·81, 95% CI 2·67-5·43, p<0·001), reoperation (3·38, 2·10-5·45, p<0·001), and removal of implant, ADM, or both (8·80, 8·24-9·40, p<0·001) than two-stage IBBR. Severe (grade 3) adverse events occurred in 26 (29%) of 91 breasts in the one-stage IBBR with ADM group and in five (5%) of 92 in the two-stage IBBR group. The frequency of mild to moderate adverse events was similar in the two groups.Interpretation: Immediate one-stage IBBR with ADM was associated with adverse events and should be considered very carefully. Understanding of selection of patients, risk factors, and surgical and postsurgical procedures needs to be improved.Funding: Pink Ribbon, Nuts-Ohra, and LifeCell.
SN  - 1470-2045
AD  - Department of Plastic, Reconstructive, and Hand Surgery, VU University Medical Centre, Amsterdam, Netherlands
AD  - EMGO Institute for Health and Care Research Amsterdam, Amsterdam, Netherlands
AD  - Alexander Monro Breast Cancer Hospital, Bilthoven, Netherlands
AD  - Department of Epidemiology and Biostatistics, VU University Medical Centre, Amsterdam, Netherlands
AD  - Department of Plastic, Reconstructive, and Hand Surgery, Meander Medical Centre, Amersfoort, Netherlands
AD  - Department of Plastic, Reconstructive, and Hand Surgery, Erasmus MC Cancer Institute, University Medical Centre Rotterdam, Rotterdam, Netherlands
AD  - Department of Plastic, Reconstructive, and Hand Surgery, Maastricht University Medical Centre, Maastricht, Netherlands
AD  - Department of Plastic, Reconstructive, and Hand Surgery, University Medical Centre Groningen, Groningen, Netherlands
AD  - Department of Plastic, Reconstructive, and Hand Surgery, Haga Ziekenhuis, Den Haag, Netherlands
AD  - Department of Plastic, Reconstructive, and Hand Surgery, Orbis Medisch Centrum, Sittard, Netherlands
U2  - PMID: 28012977.
DO  - 10.1016/S1470-2045(16)30668-4
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 125433468
T1  - One-Stage Immediate Breast Reconstruction: A Concise Review.
AU  - Bertozzi, Nicolò
AU  - Pesce, Marianna
AU  - Santi, Pierluigi
AU  - Raposio, Edoardo
Y1  - 2017/10/02/
N1  - Accession Number: 125433468. Language: English. Entry Date: 20171011. Revision Date: 20171014. Publication Type: Article; pictorial; review. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 101600173. 
KW  - Breast Neoplasms -- Surgery
KW  - Breast Reconstruction -- Methods
KW  - Treatment Outcomes
KW  - Breast Reconstruction -- Adverse Effects
KW  - Postoperative Care
KW  - Mastectomy -- Methods
KW  - Preoperative Care
KW  - Breast Reconstruction -- Contraindications
KW  - Breast Implants
KW  - Recovery
KW  - Quality of Life
KW  - Patient Satisfaction
KW  - Patient Selection
KW  - Eligibility Determination
KW  - Surgical Mesh
KW  - Autografts
KW  - Surgical Flaps
SP  - 1
EP  - 12
JO  - BioMed Research International
JF  - BioMed Research International
JA  - BIOMED RES INT
CY  - London, <Blank>
PB  - Hindawi Limited
AB  - Background. One-stage direct-to-implant immediate breast reconstruction (IBR) is performed simultaneously with breast cancer resection. We explored indications, techniques, and outcomes of IBR to determine its feasibility, safety, and effectiveness. Material and Methods. We reviewed the available literature on one-stage direct-to-implant IBR, with or without acellular dermal matrix (ADM), synthetic mesh, or autologous fat grafting. We analyzed the indications, preoperative work-up, surgical technique, postoperative care, outcomes, and complications. Results. IBR is indicated for small-to-medium nonptotic breasts and contraindicated in patients who require or have undergone radiotherapy, due to unacceptably high complications rates. Only patients with thick, well-vascularized mastectomy flaps are IBR candidates. Expandable implants should be used for ptotic breasts, while anatomical shaped implants should be used to reconstruct small-to-medium nonptotic breasts. ADMs can be used to cover the implant during IBR and avoid muscle elevation, thereby minimizing postoperative pain. Flap necrosis, reoperation, and implant loss are more common with IBR than conventional two-staged reconstruction, but IBR has advantages such as lack of secondary surgery, faster recovery, and better quality of life. Conclusions. IBR has good outcomes and patient-satisfaction rates. With ADM use, a shift from conventional reconstruction to IBR has occurred. Drawbacks of IBR can be overcome by careful patient selection.
SN  - 2314-6133
AD  - Department of Medicine and Surgery, Plastic Surgery Division, University of Parma, Parma, Italy
AD  - Cutaneous, Mini-Invasive, Regenerative and Plastic Surgery Unit, Parma University Hospital, Parma, Italy
AD  - Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy
AD  - Plastic Surgery Department, IRCCS San Martino University Hospital, National Institute for Cancer Research Genoa, Genoa, Italy
DO  - 10.1155/2017/6486859
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109643288
T1  - Postoperative Expansion is not a Primary Cause of Infection in Immediate Breast Reconstruction with Tissue Expanders.
AU  - Avraham, Tomer
AU  - Weichman, Katie E.
AU  - Wilson, Stelios
AU  - Weinstein, Andrew
AU  - Haddock, Nicholas T.
AU  - Szpalski, Caroline
AU  - Choi, Mihye
AU  - Karp, Nolan S.
Y1  - 2015/09//Sep/Oct2015
N1  - Accession Number: 109643288. Language: English. Entry Date: 20150922. Revision Date: 20160831. Publication Type: Journal Article. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Peer Reviewed; USA. Special Interest: Oncologic Care; Women's Health. NLM UID: 9505539. 
SP  - 501
EP  - 507
JO  - Breast Journal
JF  - Breast Journal
JA  - BREAST J
VL  - 21
IS  - 5
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Perioperative infection is the most common and dreaded complication associated with tissue expander ( TE) breast reconstruction. Historically, the expansion period was thought to be the time of greatest hazard to the implant. However, recent institutional observations suggest infectious complications occur prior to expansion. This investigation, therefore, was conducted to determine the timing of infectious complications associated with two-stage TE breast reconstructions. Following IRB approval, a retrospective review of all consecutive two-stage immediate TE breast reconstructions at a single institution from November 2007 to November 2011 was conducted. Reconstructions were then divided into two cohorts: those suffering infectious complications and those that did not. Infectious complications including minor cellulitis, major cellulitis, abscess drainage, and explantation were identified. Various operative and patient variables were evaluated in comparison. Eight hundred ninety immediate two-stage TE breast reconstructions met inclusion criteria. Patients suffering infection were older (55.4 years versus 49.3 years; p < 0.001), and more likely to have therapeutic mastectomy (94% versus 61%; p < 0.0001), the use of acellular dermal matrix ( ADM; 72.5% versus 54.9%; p = 0.001), and greater initial TE fill (448.6 mL versus 404.7 mL; p = 0.0078). The average time to developing of infectious symptoms was 29.6 days (range 9-142 days), with 94.6% ( n = 87) of infections prior to the start of expansion. Perioperative infections in immediate two-stage TE to implant breast reconstructions are significant and occur mostly prior to the start of expansion. Thus, challenging the conventional wisdom that instrumentation during expander filling as the primary cause of implant infections. Possible etiologic factors include greater age, therapeutic mastectomy versus prophylactic mastectomy, larger initial TE fill, and the use of ADM.
SN  - 1075-122X
AD  - Institute of Reconstructive Plastic Surgery, New York University
AD  - University of Texas Southwestern
AD  - Department of Surgery, University Libre de Bruxelles
U2  - PMID: 26132336.
DO  - 10.1111/tbj.12448
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103890098
T1  - First Experience Using Contrast-enhanced Ultrasound to Evaluate Vascularisation of Acellular Dermal Matrices after Implant-Based Breast Reconstruction.
AU  - Parvizi, Daryousch
AU  - Haas, Franz
AU  - Peintinger, Florentia
AU  - Hubmer, Martin
AU  - Rappl, Thomas
AU  - Koch, Horst
AU  - Schintler, Michael
AU  - Spendel, Stephan
AU  - Kamolz, Lars-Peter
AU  - Wurzer, Paul
AU  - Tuca, Alexandru
AU  - Fuchsjaeger, Michael
AU  - Weinke, Roland
Y1  - 2014/09//Sep/Oct2014
N1  - Accession Number: 103890098. Language: English. Entry Date: 20140912. Revision Date: 20150901. Publication Type: Journal Article; pictorial; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Peer Reviewed; USA. Special Interest: Oncologic Care; Perioperative Care; Women's Health. NLM UID: 9505539. 
KW  - Breast Reconstruction
KW  - Breast Implants
KW  - Biocompatible Materials -- Therapeutic Use
KW  - Ultrasonography -- Utilization
KW  - Mastectomy
KW  - Human
KW  - Case Studies
KW  - Retrospective Design
KW  - Software
KW  - Adult
KW  - Middle Age
KW  - Aged
KW  - Female
KW  - Radiologists
KW  - Breast Neoplasms -- Therapy
KW  - Breast Neoplasms -- Surgery
KW  - Breast Neoplasms -- Radiotherapy
KW  - Breast Neoplasms -- Drug Therapy
KW  - Radiotherapy
KW  - Chemotherapy, Cancer
KW  - Revascularization
SP  - 461
EP  - 467
JO  - Breast Journal
JF  - Breast Journal
JA  - BREAST J
VL  - 20
IS  - 5
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Acellular dermal matrices ( ADM) have been used frequently in therapeutic and prophylactic breast procedures. To date there have been no reports on vascularisation of ADMs and formation of tissue around them as seen with modern non-invasive imaging techniques such as contrast-enhanced ultrasound ( CEUS). In this case series, we used CEUS to investigate the features of ADM in relation to vascular ingrowth and scaffold for 'new' tissue formation. This is a retrospective evaluation of patients who underwent successful skin- and nipple-sparing mastectomy ( SSM, NSM) with immediate IBBR using ADM from May 31, 2010, through December 28, 2012. Over a 24-month period, 16 patients, with an average age of 44 years (range 27-70 years), were evaluated with CEUS. No contrast agent allergies or side effects were reported for the ultrasound examination. After contrast agent injection (1-18 months postoperatively), homogeneous normal enhancement in the ADM and peripheral region with physiological tissue formation was seen in all patients. In this small study, the most obvious contribution of CEUS is the in vivo evaluation of vascular ingrowth and tissue formation after IBBR with ADM after follow-up of 1-18 months postoperatively. Level of Evidence III: Retrospective cohort or comparative study; case-control study; or systematic review of these studies.
SN  - 1075-122X
AD  - Division of Plastic, Aesthetic and Reconstructive Surgery, Department of Surgery, Medical University of Graz
AD  - Department of Senology, Breast Center of University Hospital Salzburg, LKH Leoben
AD  - Department of Radiology, Medical University of Graz
U2  - PMID: 25041092.
DO  - 10.1111/tbj.12301
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 126560863
T1  - Sacrocolpopexy: A Modification of the Standard Laparoscopic Procedure to Adopt It to the Properties of a Biologic Matrix Patch.
AU  - Karon, Magdalene
Y1  - 2017/12//
N1  - Accession Number: 126560863. Language: English. Entry Date: 20171207. Revision Date: 20171207. Publication Type: Article; pictorial; research; tables/charts. Journal Subset: Biomedical; USA. Instrumentation: Pelvic Floor Distress Inventory-20 (PFDI-20); Pelvic Floor Impact Questionnaire (PFIQ). NLM UID: 9000936. 
KW  - Pelvic Organ Prolapse -- Surgery
KW  - Surgery, Gynecologic -- Methods
KW  - Surgical Mesh
KW  - Postoperative Complications -- Prevention and Control
KW  - Surgery, Laparoscopic
KW  - Human
KW  - Female
KW  - Prospective Studies
KW  - Treatment Outcomes
KW  - Patient Satisfaction
KW  - Biopsy
KW  - Histology
KW  - Pelvic Floor Muscles -- Surgery
KW  - Questionnaires
SP  - 248
EP  - 252
JO  - Journal of Gynecologic Surgery
JF  - Journal of Gynecologic Surgery
JA  - J GYNECOL SURG
VL  - 33
IS  - 6
CY  - New Rochelle, New York
PB  - Mary Ann Liebert, Inc.
AB  - Objective: By 80 years of age, 11.1% of women are expected to undergo pelvic organ prolapse (POP) surgery and one-third of women are expected to undergo reoperation. The 'gold standard' procedure is sacrocolpopexy, which uses a graft to support the vaginal apex to the ligaments of the sacrum. The conventional graft (polypropylene mesh) has been associated with dyspareunia, persistent pelvic pain, and increased mesh erosion. In an effort to combat these complications, a noncrosslinked acellular dermal matrix (ADM; STRATTICE™ Reconstructive Matrix, LifeCell, an ACELITY Company, Bridgewater, NJ) was utilized for this study. Materials and Methods: Sacrocolpopexy, with ADM, was used for 9 patients between January 2011 and December 2013. The patients completed Pelvic Floor Distress Inventory-20 (PFDI-20) and pelvic floor impact questionnaires and reported on postsurgical outcome satisfaction. Patient satisfaction with clinical outcomes was assessed. Biopsies of the sacrocolpopexy were performed and tissue samples were sent for histology testing if a patient returned for another procedure. Results: During sacrocolpopexy, an ADM was trimmed to fit each patient's anatomy, attached to the vaginal cuff or cervix using sutures, and, when possible, incorporated with the round ligament on each side. The entire sacrocolpopexy was kept in the retroperitoneal space. The postoperative PFDI-20 average score was 25.47 ± 29.68. The postsurgical pelvic floor impact score was, on average, 98%. Patient reported satisfaction with postsurgical outcomes ranged from 70% to 100%. Histology testing showed dense and loose connective tissue with blood vessels, and fibroblast cells and minimal inflammation. Conclusions: Other specialties have adopted the use of ADM for defect repairs and breast reconstruction. ADMs can also be used in sacrocolpopexy. (J GYNECOL SURG 33:248)
SN  - 1042-4067
DO  - 10.1089/gyn.2017.0060
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 128331912
T1  - One‐stage muscle‐sparing breast reconstruction in elderly patients: A new tool for retaining excellent quality of life.
AU  - Maruccia, Michele
AU  - Di Taranto, Giuseppe
AU  - Onesti, Maria G.
Y1  - 2018/03//
N1  - Accession Number: 128331912. Language: English. Entry Date: 20180309. Revision Date: 20180309. Publication Type: Article; pictorial; research. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Peer Reviewed; USA. NLM UID: 9505539. 
KW  - Breast Neoplasms -- Surgery
KW  - Breast Reconstruction -- Methods -- In Old Age
KW  - Quality of Life
KW  - Patient Safety
KW  - Human
KW  - Female
KW  - Aged
KW  - Aged, 80 and Over
SP  - 180
EP  - 183
JO  - Breast Journal
JF  - Breast Journal
JA  - BREAST J
VL  - 24
IS  - 2
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Abstract: More than 50% of breast cancer care occurs in elderly but women aged 65 and over generally have lower breast reconstruction (BR) rates. In medical literature, few papers focused on BR in elderly patients and usually the reported techniques are multisteps such as expander‐implant reconstruction, local, and free flaps. We present a one‐stage reconstruction technique employed in elderly patients: muscle‐sparing immediate BR with subcutaneous implant and Braxon acellular dermal matrix. We prove the feasibility and safety of the technique and believe that this new procedure could represent a potential benefit in elderly BR.
SN  - 1075-122X
AD  - Department of Plastic and Reconstructive Surgery, Sapienza University, Rome, Italy
DO  - 10.1111/tbj.12860
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 128981116
T1  - Prepectoral Revision Breast Reconstruction for Treatment of Implant-Associated Animation Deformity: A Review of 102 Reconstructions.
AU  - Gabriel, Allen
AU  - Sigalove, Steven
AU  - Sigalove, Noemi M.
AU  - Storm-Dickerson, Toni L.
AU  - Rice, Jami
AU  - Pope, Nicole
AU  - Maxwell, G. Patrick
AU  - Patrick Maxwell, G
Y1  - 2018/05//
N1  - Accession Number: 128981116. Language: English. Entry Date: In Process. Revision Date: 20180414. Publication Type: journal article. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. NLM UID: 9707469. 
SP  - 519
EP  - 526
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 38
IS  - 5
PB  - Oxford University Press / USA
AB  - Background: Animation deformity is a direct consequence of subpectoral implant placement for breast reconstruction following mastectomy. Current treatment options ameliorate but do not address the source of the problem. Moving the implant from subpectoral to prepectoral has the potential to eliminate animation deformity.Objectives: Describe the technique and outcomes of prepectoral revision reconstruction in over 100 cases and discuss patient selection criteria for a successful outcome.Methods: Patients who presented with animation deformity following two-stage implant reconstruction were included in this retrospective study. Revision surgery involved removal of the existing implant via the previous incision site along the inframammary fold, suturing of the pectoralis major muscle back to the chest wall, creation of a prepectoral pocket for the new implant, use of acellular dermal matrix to reinforce the prepectoral pocket and completely cover the implant, and fat grafting to enhance soft tissue. Patients were evaluated for resolution of animation deformity and occurrence of complications during follow up.Results: Fifty-seven patients (102 breasts) underwent prepectoral revision reconstruction with complete resolution of animation deformity. Complications occurred in 4 breasts (3.9%) and included seroma (2 breasts), skin necrosis (3 breasts), and wound dehiscence (1 breast). All 4 breasts with complications had their implants removed and replaced. There were no incidences of infection or clinically significant capsular contracture in this series.Conclusions: Revision reconstruction with prepectoral implant placement and complete coverage with acellular dermal matrix resolves animation deformity and results in aesthetically pleasing soft breasts. Patient selection is critical for the success of this technique.Level of Evidence4:
SN  - 1090-820X
AD  - Clinical Associate Professor of Surgery, Department of Plastic Surgery, Loma Linda University Medical Center, Loma Linda, CA
AD  - Chairman, Department of Plastic Surgery, Central DuPage Hospital/Northwestern Medicine, Winfield IL
AD  - Breast Program Director, Department of Breast Surgery, Central DuPage Hospital/Northwestern Medicine, Winfield, IL
AD  - Breast Program Co-director, Compass Oncology Breast Specialists, Compass Oncology, Portland, OR
AD  - Plastic Surgery Nurse Practitioner, PeaceHealth Medical Group, Vancouver, WA
AD  - Plastic Surgery Nurse Practitioner, DuPage Medical Group, Winfield, IL
AD  - Clinical Professor of Surgery, Department of Plastic Surgery, Loma Linda University Medical Center, Loma Linda, CA
AD  - Department of Plastic Surgery, Loma Linda University Medical Center, Loma Linda, CA
U2  - PMID: 29365064.
DO  - 10.1093/asj/sjx261
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 125064094
T1  - Muscle-Sparing ADM-Assisted Breast Reconstruction Technique Using Complete Breast Implant Coverage: A Dual-Institute UK-Based Experience.
AU  - Vidya, Raghavan
AU  - Cawthorn, Simon J.
Y1  - 2017/09//
N1  - Accession Number: 125064094. Language: English. Entry Date: 20170912. Revision Date: 20180119. Publication Type: Article; pictorial; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. NLM UID: 101254060. 
KW  - Breast Implants
KW  - Breast Reconstruction -- Methods
KW  - Pectoralis Muscles
KW  - Human
KW  - United Kingdom
KW  - Surgical Mesh
KW  - Treatment Outcomes
SP  - 251
EP  - 254
JO  - Breast Care
JF  - Breast Care
JA  - BREAST CARE
VL  - 12
IS  - 4
PB  - Karger AG
AB  - Background: We report our early experience of a novel muscle-sparing breast (prepectoral) reconstruction technique using a pre-shaped Braxon® mesh (acellular dermal matrix) which completely wraps around the breast implant. Methods: All patients who underwent prepectoral implant-based breast reconstruction between April 2014 and September 2015 were included in the analysis. The dermal matrix Braxon® used is a pre-shaped matrix which forms a complete implant mesh wrap. The new breast created is placed over the chest wall without disturbing the pectoralis musculature. Results: A total of 51 (42 unilateral and 9 bilateral) muscle-sparing breast reconstructions were carried out. Complications included implant loss (n = 1; 1.7%) secondary to wound infection, seroma (n = 4; 6.7%), and superficial wound dehiscence (n = 1; 1.7%) which was re-sutured without further complication. The median follow-up period was 16.4 (range 8-25) months. Conclusion: The early experience appears highly satisfactory with good clinical outcome. The novel prepectoral implant-based breast reconstruction using the mesh wrap provides an effective alternative to the more traditional submuscular implant-based technique.
SN  - 1661-3791
AD  - Breast Care Centre, Royal Wolverhampton Hospital NHS Trust, Wolverhampton, United Kingdom
AD  - Breast Care Centre, North Bristol NHS Trust, Southmead Hospital, Bristol, United Kingdom
DO  - 10.1159/000464401
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 125188900
T1  - Revisiting an Old Place: Single-Surgeon Experience on Post-Mastectomy Subcutaneous Implant-Based Breast Reconstruction.
AU  - Woo, Alice
AU  - Harless, Christin
AU  - Jacobson, Steven R.
Y1  - 2017/09//
N1  - Accession Number: 125188900. Language: English. Entry Date: 20170919. Revision Date: 20170919. Publication Type: Article; pictorial; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Peer Reviewed; USA. NLM UID: 9505539. 
KW  - Mastectomy
KW  - Breast Reconstruction
KW  - Breast Implants
KW  - Surgeons
KW  - Patient Safety
KW  - Human
KW  - Female
KW  - Retrospective Design
SP  - 545
EP  - 553
JO  - Breast Journal
JF  - Breast Journal
JA  - BREAST J
VL  - 23
IS  - 5
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Significant advances have been made to the reconstructive tools available to plastic surgeons allowing for the re-exploration of subcutaneous breast reconstruction. The purpose of the current study is to examine the safety, efficacy, and aesthetic results of subcutaneous breast reconstruction by a single-surgeon. A retrospective chart review was performed on all patients undergoing subcutaneous implant-based breast reconstruction between April 2012 and September 2014. All implants were fully wrapped in Alloderm and placed in the subcutaneous (pre-pectoral) plane. Primary outcome was a successful subcutaneous breast reconstruction. All complications were recorded. Aesthetics of the preoperative and postoperative photographs were examined. A total of 135 breasts (79 patients) were reconstructed. Direct-to-implant reconstruction was performed in 8 patients (10%). Successful breast reconstruction was achieved for 130 breasts in 76 patients (96%). Sixty-nine patients (87%) had a course free of any unexpected event or complication. There were no patients with implant extrusion or skin necrosis requiring operative intervention. When comparing pre-mastectomy breasts with post-mastectomy reconstructions, there was an improvement in the overall aesthetic outcome. Subcutaneous post-mastectomy breast reconstruction is safe and effective with comparable complication rates to standard techniques. Yet, this minimally invasive approach does not sacrifice the aesthetic results. Long-term studies will be required to prove the durability of aesthetic results overtime.
SN  - 1075-122X
AD  - Department of Surgery Plastic, Surgery Mayo Clinic
DO  - 10.1111/tbj.12790
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 117941396
T1  - Ultrasonography Findings of AlloDerm® Used in Postmastectomy Alloplastic Breast Reconstruction: A Case Report and Literature Review.
AU  - Young Seon Kim
Y1  - 2016/07//
N1  - Accession Number: 117941396. Language: English. Entry Date: 20170513. Revision Date: 20170515. Publication Type: Article; case study; diagnostic images. Journal Subset: Biomedical; Middle East. NLM UID: 101233229. 
KW  - Dermal Fillers
KW  - Breast -- Ultrasonography
KW  - Mastectomy
KW  - Breast Reconstruction
KW  - Female
KW  - Adult
KW  - Postoperative Period
KW  - Diagnostic Errors
KW  - Neoplasm Recurrence, Local
SP  - 1
EP  - 4
JO  - Iranian Journal of Radiology
JF  - Iranian Journal of Radiology
JA  - IRANIAN J RADIOL
VL  - 13
IS  - 3
PB  - Tehran University of Medical Sciences
AB  - AlloDerm® (LifeCell Corp.; Brancburg, NJ) is an acellular dermal matrix (ADM) that serves as an immunologically inert scaffold in plastic surgery. In breast reconstruction, it is used as a filler for lumpectomy defects and can be used to create the inferolateral portion of the tissue expander pocket or implant pocket in postmastectomy patients. However, there are limited reports of the radiologic findings of AlloDerm® in patients who have undergone postmastectomy reconstruction. Familiarity with the imaging features of AlloDerm® is essential for correct diagnosis. We report the ultrasonography features of AlloDerm® in a 43-year-old female patient 3 months after postmastectomy reconstruction. It may help distinguish AlloDerm® from tumor recurrence or other foreign body materials such as gossypiboma. This is important as misdiagnosis can often lead to unnecessary surgical intervention.
SN  - 1735-1065
AD  - Department of Radiology, College of Medicine, Yeungnam University, Daegu, Korea
DO  - 10.5812/iranjradiol.38252
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 126821937
T1  - A Tumor Ultrasound-guided Incision (TUGI) Approach to Nipple-sparing Mastectomy: Balancing Oncologic Safety and Technical Outcomes.
AU  - Fernando, Emil J.
AU  - Eskenazi, Benjamin R.
AU  - Djohan, Risal S.
AU  - Grobmyer, Stephen R.
Y1  - 2017/11//
N1  - Accession Number: 126821937. Language: English. Entry Date: In Process. Revision Date: 20171221. Publication Type: journal article. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 100898731. 
SP  - 572
EP  - 577
JO  - Clinical Breast Cancer
JF  - Clinical Breast Cancer
JA  - CLIN BREAST CANCER
VL  - 17
IS  - 7
CY  - New York, New York
PB  - Elsevier B.V.
AB  - Background: Nipple-sparing mastectomy (NSM) is a prevalent operation for patients with breast cancer. Indications have been limited to tumors accessible via radial, infra-mammary, or periareolar incisions out of concern for oncologic and technical safety. We study an alternative approach to NSM based on tumor ultrasound-guided incisions (TUGI) and report its oncologic and technical outcomes.Materials and Methods: A retrospective chart review examined patients who underwent TUGI NSM between 2013 and 2016. Operative notes, postoperative notes, pathology reports, and postoperative photography were analyzed.Results: Ninety-four patients had mastectomy with reconstruction performed over a 3-year period by the senior authors. Of those, 31 (33%) were NSM and 13 (14%) had the TUGI technique, forming the study group. The median tumor size was 1.5 cm, with a median distance from the nipple areolar complex of 5 cm. Sixty-two percent of the incisions were in the upper quadrants of the breast. Median operative time was 207 minutes. Zero patients had positive margins. One hundred percent of patients underwent immediate tissue expander placement, 46% with acellular dermal matrix. For final reconstruction, 23% had a free flap, 69% implant, and 8% are still pending. Eight percent of patients had wound infection, and 15% of patients had NAC necrosis. No cancer recurrence has been observed at a median follow-up of 17 months.Conclusion: TUGI offers a valuable, oncologically sound alternative approach to traditional NSM. The technical results and outcomes support its use in selected patients with breast cancer undergoing NSM.
SN  - 1526-8209
AD  - Division of Surgical Oncology, Department of General Surgery, Cleveland Clinic, Cleveland, OH
AD  - Department of Plastic Surgery, Cleveland Clinic, Cleveland, OH
U2  - PMID: 28495572.
DO  - 10.1016/j.clbc.2017.04.003
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 126090110
T1  - Evaluation of the effectiveness of the prepectoral breast reconstruction with Braxon dermal matrix: First multicenter European report on 100 cases.
AU  - Vidya, Raghavan
AU  - Masià, Jaume
AU  - Cawthorn, Simon
AU  - Berna, Giorgio
AU  - Bozza, Fernando
AU  - Gardetto, Alexander
AU  - Kołacińska, Agnieszka
AU  - Dell'Antonia, Francesco
AU  - Tiengo, Cesare
AU  - Bassetto, Franco
AU  - Caputo, Glenda G.
AU  - Governa, Maurizio
Y1  - 2017/11//
N1  - Accession Number: 126090110. Language: English. Entry Date: 20171113. Revision Date: 20171113. Publication Type: Article; pictorial; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Peer Reviewed; USA. NLM UID: 9505539. 
KW  - Breast Reconstruction -- Methods
KW  - Dermis -- Transplantation
KW  - Breast Implants
KW  - Treatment Outcomes
KW  - Pectoralis Muscles
KW  - Esthetics
KW  - Human
KW  - Female
KW  - Multicenter Studies
KW  - Descriptive Statistics
KW  - Prospective Studies
KW  - Europe
SP  - 670
EP  - 676
JO  - Breast Journal
JF  - Breast Journal
JA  - BREAST J
VL  - 23
IS  - 6
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - We report the outcomes of the European prospective study on prepectoral breast reconstruction using preshaped acellular dermal matrix for complete breast implant coverage. Seventy-nine patients were enrolled between April 2014 and August 2015 all over Europe using a single protocol for patient selection and surgical procedure, according to the Association of Breast Surgery and British Association of Plastic Reconstructive and Aesthetic Surgeons joint guidelines for the use of acellular dermal matrix in breast surgery. The preshaped matrix completely wraps the breast implant, which is placed above the pectoralis major, without detaching the muscle. A total of 100 prepectoral breast reconstructions with complete implant coverage were performed. This series, with mean follow-up of 17.9 months, had two cases of implant loss (2.0%) including one necrosis of the nipple and one wound breakdown (1.0% respectively). No implant rotations were observed. Good cosmetic outcomes were obtained with natural movement of the breasts and softness to the touch; none of the patients reported experiencing pain or reduction in the movements of the pectoralis major muscle postoperatively. The use of preshaped acellular dermal matrix for a complete breast implant coverage in selected patients is safe and gives satisfactory results, both from the aesthetic view point and the low postoperative complication rates. Further studies reporting long-term outcomes are planned.
SN  - 1075-122X
AD  - Breast Care Center, Royal Wolverhampton Hospital
AD  - Plastic and Reconstructive Surgery Department, Hospital de la Santa Creu i Sant Pau (Universitat Autònoma de Barcelona)
AD  - Breast Care Center, North Bristol NHS Trust
AD  - Plastic and Reconstructive Surgery Department, Ulss 9 General Hospital
AD  - Breast Care Center, Venetian Oncology Institute
AD  - Plastic and Reconstructive Surgery Department, South Tyrol Healthcare Company
AD  - Department of Surgical Oncology and Head and Neck Cancer Surgery, Medical University of Lodz, Cancer Center Copernicus Memorial Hospital, Medical University of Lodz
AD  - Plastic and Reconstructive Surgery Department, University Hospital of Padua
AD  - Plastic and Reconstructive Surgery, Surgery and Odontology Department, University Hospital of Verona
DO  - 10.1111/tbj.12810
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 118903401
T1  - Do Processing Methods Make a Difference in Acellular Dermal Matrix Properties?
AU  - Nilsen, Todd J.
AU  - Dasgupta, Anouska
AU  - Yen-Chen Huang
AU  - Wilson, Henry
AU  - Chnari, Evangelia
AU  - Huang, Yen-Chen
Y1  - 2016/11/02/2016 Supplement
N1  - Accession Number: 118903401. Language: English. Entry Date: In Process. Revision Date: 20171102. Publication Type: journal article. Supplement Title: 2016 Supplement. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Instrumentation: Work Environment Scale (WES) (Moos et al). NLM UID: 9707469. 
KW  - Surgery, Reconstructive -- Methods
KW  - Collagen
KW  - Dermis
KW  - Fibroblasts -- Physiology
KW  - Sterilization and Disinfection
KW  - Cells, Cultured
KW  - Breast Reconstruction -- Methods
KW  - Decontamination, Hazardous Materials
KW  - Cell Physiology
KW  - Kinematics
KW  - Scales
SP  - S7
EP  - S22
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 36
PB  - Oxford University Press / USA
AB  - Background: The use of acellular dermal matrices (ADMs) has become the standard of practice in many reconstructive and aesthetic surgical applications. Different methods used to prepare the allograft tissue for surgical use can alter the ADMs natural properties. Aseptic processing has been shown to retain the natural properties of ADMs more favorably than terminally sterilized ADMs. Terminal sterilization has been historically linked to alteration of biological materials. In vitro work was conducted to compare ADM processing methods.Objectives: Characterize aseptically processed ADMs and compare cell-matrix interaction characteristics to terminally sterilized ADMs.Methods: Two aseptically processed ADMs, FlexHD Pliable and BellaDerm, were characterized via histological evaluation, biomechanical integrity, enzymatic degradation, and in vitro cell studies. FlexHD Pliable was compared to Alloderm Ready-to-Use (RTU).Results: Histological evaluation revealed that FlexHD Pliable had a uniform, open structure compared to BellaDerm. Mechanical characterization demonstrated that BellaDerm had higher strength and stiffness compared to FlexHD Pliable, which maintained higher elasticity. Immunohistochemical analysis verified that key matrix proteins remained intact after aseptic processing. Cell studies found that fibroblasts attached more readily, and proliferated faster on FlexHD Pliable compared to BellaDerm. Additionally, fibroblasts infiltrated into FlexHD Pliable from both sides and on the dermal side in BellaDerm and produced an abundance of multi-layered matrix proteins (collagen, fibronectin) when compared to AlloDerm RTU which was sparse.Conclusions: Aseptically processed FlexHD Pliable and BellaDerm provide a suitable, biocompatible option for tissue repair and regeneration in aesthetic and reconstructive surgical applications.
SN  - 1090-820X
AD  - Senior Engineer, Wound Care, and General and Plastic Surgery Musculoskeletal Transplant Foundation, Edison, NJ
AD  - Senior Scientist, Wound Care, and General and Plastic Surgery Musculoskeletal Transplant Foundation, Edison, NJ
AD  - Staff Scientist, Research and Development and Allograft Materials Research, Musculoskeletal Transplant Foundation, Edison, NJ
AD  - Clinical Assistant Professor of Plastic Surgery, Liberty University College of Osteopathic Medicine, Lynchburg, VA
AD  - Associate Director, Research and Development, Wound Care, and General and Plastic Surgery Musculoskeletal Transplant Foundation, Edison, NJ
AD  - Mr Nilsen is a Senior Engineer, Dr Dasgupta is a Senior Scientist, and Dr Chnari is an Associate Director, Research and Development, Wound Care, and General and Plastic Surgery; and Dr Huang is a Staff Scientist, Research and Development and Allograft Materials Research, Musculoskeletal Transplant Foundation, Edison, NJ. Dr Wilson is a Clinical Assistant Professor of Plastic Surgery, Liberty University College of Osteopathic Medicine, Lynchburg, VA
U2  - PMID: 27697888.
DO  - 10.1093/asj/sjw163
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 123919593
T1  - Previously Published Article. Acellular Dermal Matrix for the Treatment and Prevention of Implant-Associated Breast Deformities...Reprinted with permission from Plastic and Reconstructive Surgery, March 2011, vol. 127, no. 3, pp 1047-1058.
AU  - Spear, Scott L.
AU  - Seruya, Mitchel
AU  - Clemens, Mark W.
AU  - Teitelbaum, Steven
AU  - Nahabedian, Maurice Y.
Y1  - 2017/04//Apr-Jun2017
N1  - Accession Number: 123919593. Language: English. Entry Date: In Process. Revision Date: 20170706. Publication Type: Article; case study; pictorial; research; tables/charts. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. NLM UID: 8403490. 
KW  - Breast Implants -- Adverse Effects
KW  - Breast -- Abnormalities
KW  - Surgery, Reconstructive
KW  - Dermis -- Surgery
KW  - Postoperative Complications -- Prevention and Control
KW  - Human
KW  - Retrospective Design
KW  - Female
KW  - Adult
KW  - Middle Age
KW  - Aged
SP  - 76
EP  - 87
JO  - Plastic Surgical Nursing
JF  - Plastic Surgical Nursing
JA  - PLAST SURG NURS
VL  - 37
IS  - 2
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - Background: Acellular dermal matrix has been increasingly accepted in prosthetic breast reconstruction. Observed benefits include improved control and support of implant position, better implant coverage, and the suggestion of a decreased capsular contracture rate. Based on this positive experience, it is not surprising that acellular dermal matrix would be applied to other challenging implant-related problems. This study investigates the use of acellular dermal matrix for correction or prevention of implant-associated breast deformities. Methods: Patients who underwent primary aesthetic breast surgery or secondary aesthetic or reconstructive breast surgery using acellular dermal matrix and implants between November of 2003 and October of 2009 were reviewed retrospectively. Patient demographics, indications for acellular dermal matrix, and acellular dermal matrix type and inset pattern were identified. Preoperative and postoperative photographs, success or failure of the procedure, complications, and need for related or unrelated revision surgery were recorded. Results: Fifty-two patients had acellular dermal matrix placed alongside 77 breast prostheses, with a mean follow-up of 8.6 months (range, 0.4 to 30.4 months). Indications included prevention of implant bottoming-out (n = 6), treatment of malposition (n = 32), rippling (n = 20), capsular contracture (n = 16), and skin flap deficiency (n = 16). Seventy-four breasts (96.1 percent) were managed successfully with acellular dermal matrix. Three failures consisted of one breast with bottoming-out following treatment of capsular contracture, one breast with major infection requiring device explantation, and one breast with recurrent rippling. There was a 9.1 percent total complication rate, consisting of three mild infections, one major infection necessitating explantation, one hematoma, and one seroma. Conclusion: Based on this experience in 77 breasts, acellular dermal matrix has shown promise in treating and preventing capsular contracture, rippling, implant malposition, and soft-tissue thinning.
SN  - 0741-5206
AD  - Department of Plastic Surgery, Georgetown University Hospital
AD  - David Geffen School of Medicine at the University of California, Los Angeles
DO  - 110.1097/PSN.0000000000000189
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 128331933
T1  - Prepectoral implant‐based breast reconstruction; complete acellular dermal matrix wrap or anterior circumferential cover...Vidya R, Masia J, Cawthorn S, et al. Evaluation of the effectiveness of the prepectoral breast reconstruction with Braxon dermal matrix: first multicenter European report on 100 cases. Breast J . 2017
AU  - Nadeem, Rana
Y1  - 2018/03//
N1  - Accession Number: 128331933. Language: English. Entry Date: 20180309. Revision Date: 20180309. Publication Type: Article; commentary; letter; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Peer Reviewed; USA. NLM UID: 9505539. 
KW  - Mastectomy
KW  - Breast Reconstruction -- Methods
KW  - Breast Reconstruction -- Equipment and Supplies
KW  - Prostheses and Implants
KW  - Decision Making, Clinical
KW  - Outcomes (Health Care)
SP  - 223
EP  - 224
JO  - Breast Journal
JF  - Breast Journal
JA  - BREAST J
VL  - 24
IS  - 2
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 1075-122X
AD  - Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK
DO  - 10.1111/tbj.12881
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 128331934
T1  - Reply to Rana Nadeem's Letter to the Editor...Nadeem R. Prepectoral implant-based breast reconstruction; complete acellular dermal matrix wrap or anterior circumferential cover; Breast J. Mar 2018; 24:2, 223-224.
AU  - Vidya, Raghavan
AU  - Masià, Jaume
AU  - Cawthorn, Simon
AU  - Berna, Giorgio
AU  - Bozza, Fernando
AU  - Gardetto, Alexander
AU  - Kolacinska, Agnieszka
AU  - Dell'Antonia, Francesco
AU  - Tiengo, Cesare
AU  - Bassetto, Franco
AU  - Caputo, Glenda G.
AU  - Governa, Maurizio
Y1  - 2018/03//
N1  - Accession Number: 128331934. Language: English. Entry Date: 20180309. Revision Date: 20180309. Publication Type: Article; letter; response. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Peer Reviewed; USA. NLM UID: 9505539. 
KW  - Mastectomy
KW  - Breast Reconstruction -- Methods
KW  - Breast Reconstruction -- Equipment and Supplies
KW  - Prostheses and Implants -- Standards
KW  - Patient Selection
KW  - Patient Safety
SP  - 225
EP  - 226
JO  - Breast Journal
JF  - Breast Journal
JA  - BREAST J
VL  - 24
IS  - 2
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 1075-122X
AD  - Breast Care Center, Royal Wolverhampton Hospital, Wolverhampton, UK
AD  - Plastic and Reconstructive Surgery Department, Hospital de la Santa Creu i Sant Pau (Universitat Autònoma de Barcelona), Barcelona, Spain
AD  - Breast Care Center, North Bristol NHS Trust, Bristol, UK
AD  - Plastic and Reconstructive Surgery Department, Ulss 9 General Hospital, Treviso, Italy
AD  - Breast Care Center, Venetian Oncology Institute, Padova, Italy
AD  - Plastic and Reconstructive Surgery Department, South Tyrol Healthcare Company, Brixen, Italy
AD  - Cancer Center Copernicus Memorial Hospital, Medical University of Lodz, Lodz, Poland
AD  - Plastic and Reconstructive Surgery Department, University Hospital of Padua, Padua, Italy
AD  - Plastic and Reconstructive Surgery, Surgery and Odontology Department, University Hospital of Verona, Verona, Italy
DO  - 10.1111/tbj.12882
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 121857610
T1  - Extended Submuscular Implant-Based Breast Reconstruction with Pectoralis-Serratus Sling and Acellular Dermal Matrix.
AU  - Kolker, Adam R.
AU  - Piccolo, Paulo P.
Y1  - 2017/04//
N1  - Accession Number: 121857610. Language: English. Entry Date: 20170903. Revision Date: 20180402. Publication Type: journal article. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. NLM UID: 9707469. 
SP  - 485
EP  - 491
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 37
IS  - 4
PB  - Oxford University Press / USA
SN  - 1090-820X
AD  - Dubin Breast Center at Mount Sinai, New York, NY
AD  - Department of Surgery, Division of Plastic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY
U2  - PMID: 28364524.
DO  - 10.1093/asj/sjw200
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 115383908
T1  - Are Prophylactic Postoperative Antibiotics Necessary for Immediate Breast Reconstruction? Results of a Prospective Randomized Clinical Trial.
AU  - Phillips, Brett T.
AU  - Fourman, Mitchell S.
AU  - Bishawi, Muath
AU  - Zegers, Mary
AU  - O'Hea, Brian J.
AU  - Ganz, Jason C.
AU  - Huston, Tara L.
AU  - Dagum, Alexander B.
AU  - Khan, Sami U.
AU  - Bui, Duc T.
AU  - O'Hea, Brian J
Y1  - 2016/06//
N1  - Accession Number: 115383908. Language: English. Entry Date: 20170728. Revision Date: 20170728. Publication Type: journal article; research; randomized controlled trial. Journal Subset: Biomedical; USA. Special Interest: Evidence-Based Practice. Instrumentation: Social Support Index; Clinical Decision Making in Nursing Scale (CDMNS) (Jenkins). NLM UID: 9431305. 
KW  - Antibiotics -- Administration and Dosage
KW  - Antibiotic Prophylaxis -- Methods
KW  - Postoperative Care -- Methods
KW  - Clindamycin -- Administration and Dosage
KW  - Breast Reconstruction -- Methods
KW  - Cefazolin -- Administration and Dosage
KW  - Surgical Wound Infection -- Prevention and Control
KW  - Antibiotics -- Therapeutic Use
KW  - Mastectomy
KW  - Treatment Outcomes
KW  - Prospective Studies
KW  - Cefazolin -- Therapeutic Use
KW  - Administration, Oral
KW  - Middle Age
KW  - Surgical Wound Infection -- Diagnosis
KW  - Aged
KW  - Infusions, Intravenous
KW  - Drug Administration Schedule
KW  - Clindamycin -- Therapeutic Use
KW  - Adolescence
KW  - Female
KW  - Surgical Wound Infection -- Epidemiology
KW  - Adult
KW  - Human
KW  - Aged, 80 and Over
KW  - Young Adult
KW  - Validation Studies
KW  - Comparative Studies
KW  - Evaluation Research
KW  - Multicenter Studies
KW  - Randomized Controlled Trials
KW  - Scales
KW  - Social Support Index
SP  - 1116
EP  - 1124
JO  - Journal of the American College of Surgeons
JF  - Journal of the American College of Surgeons
JA  - J AM COLL SURG
VL  - 222
IS  - 6
CY  - New York, New York
PB  - Elsevier B.V.
AB  - Background: Closed-suction drains, implants, and acellular dermal matrix (ADM) are routinely used in tissue expander-based immediate breast reconstruction (TE-IBR). Each of these factors is thought to increase the potential for surgical site infection (SSI). Although CDC guidelines recommend only 24 hours of antibiotic prophylaxis after TE-IBR, current clinical practices vary significantly. This study evaluated the difference in SSI between 2 different prophylactic antibiotic durations.Study Design: A noninferiority randomized controlled trial was designed in which TE-IBR patients received antibiotics either 24 hours postoperatively or until drain removal. The primary outcome was SSI, as defined by CDC criteria. Operative and postoperative protocols were standardized. Secondary endpoints included clinical outcomes up to 1 year and all implant loss, or reoperation.Results: There were 112 TE-IBR patients (180 breasts) using ADM who were randomized into 2 study arms, with 62 patients in the 24-hour group and 50 in the extended group. Surgical site infection was diagnosed in 12 patients in the 24-hour group and 11 in the extended group (19.4% vs 22.0%, p = 0.82). The extended group had 7 patients who required IV antibiotics and an overall implant loss in 7 patients (14.0%). The 24-hour group had 4 patients who required IV antibiotics, with 3 requiring removal (4.8%). Patients with diabetes, postoperative seroma, or wound dehiscence were all more likely to develop SSI (p < 0.02).Conclusions: In a randomized controlled noninferiority trial, 24 hours of antibiotics is equivalent to extended oral antibiotics for SSI in TE-IBR patients. Additional multicenter trials will further assess this important aspect of TE-IBR postoperative care.
SN  - 1072-7515
AD  - Division of Plastic, Maxillofacial, and Oral Surgery, Duke University Hospital, Durham, NC
AD  - Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA
AD  - Division of Cardiovascular and Thoracic Surgery, Duke University Hospital, Durham, NC
AD  - Department of Surgery, Stony Brook University Hospital, Stony Brook, NY
AD  - Division of Breast Surgery, Stony Brook University Hospital, Stony Brook, NY
AD  - Division of Plastic and Reconstructive Surgery, Stony Brook University Hospital, Stony Brook, NY
U2  - PMID: 27106640.
DO  - 10.1016/j.jamcollsurg.2016.02.018
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 116936391
T1  - Decreased hernia recurrence using autologous platelet-rich plasma (PRP) with Strattice™ mesh in a rodent ventral hernia model.
AU  - Eps, Jeffrey
AU  - Fernandez-Moure, Joseph
AU  - Cabrera, Fernando
AU  - Wang, Xin
AU  - Karim, Azim
AU  - Corradetti, Bruna
AU  - Chan, Paige
AU  - Dunkin, Brian
AU  - Tasciotti, Ennio
AU  - Weiner, Bradley
AU  - Ellsworth, Warren
AU  - Van Eps, Jeffrey
AU  - Ellsworth, Warren 4th
Y1  - 2016/08//
N1  - Accession Number: 116936391. Language: English. Entry Date: 20170806. Revision Date: 20180129. Publication Type: journal article. Journal Subset: Biomedical; Continental Europe; Europe; Expert Peer Reviewed; Peer Reviewed. NLM UID: 8806653. 
KW  - Herniorrhaphy -- Methods
KW  - Collagen
KW  - Hernia -- Surgery
KW  - Surgical Mesh
KW  - Platelet-Rich Plasma
KW  - Animals
KW  - Models, Biological
KW  - Dermis
KW  - Rats
KW  - Adhesions -- Epidemiology
KW  - Postoperative Complications -- Epidemiology
KW  - Recurrence
KW  - Prostheses and Implants
KW  - Models, Anatomic
SP  - 3239
EP  - 3249
JO  - Surgical Endoscopy
JF  - Surgical Endoscopy
JA  - SURG ENDOSC
VL  - 30
IS  - 8
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
AB  - Background: Recurrence after ventral hernia repair (VHR) remains a multifactorial problem still plaguing surgeons today. Some of the many contributing factors include mechanical strain, poor tissue-mesh integration, and degradation of matrices. The high recurrence rate witnessed with the use of acellular dermal matrices (ADM) for definitive hernia repair has reduced their use largely to bridging repair and breast reconstruction. Modalities that improve classic cellular metrics of successful VHR could theoretically result in improved rates of hernia recurrence; autologous platelet-rich plasma (PRP) may represent one such tool, but has been underinvestigated for this purpose.Methods: Lewis rats (32) had chronic ventral hernias created surgically and then repaired with Strattice™ mesh alone (control) or mesh + autologous PRP. Samples were harvested at 3 and 6 months postoperatively and compared for gross, histologic, and molecular outcomes of: neovascularization, tissue incorporation, peritoneal adhesions, hernia recurrence, and residual mesh thickness.Results: Compared to control at 3 months postoperatively, PRP-treated rats displayed significantly more neovascularization of implanted mesh and considerable upregulation of both angiogenic genes (vEGF 2.73-fold, vWF 2.21-fold) and myofibroblastic genes (αSMA 9.68-fold, FSP-1 3.61-fold, Col1a1 3.32-fold, Col31a1 3.29-fold). Histologically, they also showed enhanced tissue deposition/ingrowth and diminished chronic immune cell infiltration. Peritoneal adhesions were less severe at both 3 (1.88 vs. 2.94) and 6 months (1.63 vs. 2.75) by Modified Hopkins Adhesion Scoring. PRP-treated rats experienced decreased hernia recurrence at 6 months (0/10 vs. 7/10) and had significantly improved ADM preservation as evidenced by quantification of residual mesh thickness.Conclusions: PRP is an autologous source of pro-regenerative growth factors and chemokines uniquely suited to soft tissue wound healing. When applied to a model of chronic VHR, it incites enhanced angiogenesis, myofibroblast recruitment and tissue ingrowth, ADM preservation, less severe peritoneal adhesions, and diminished hernia recurrence. We advocate further investigation regarding PRP augmentation of human VHR.
SN  - 0930-2794
AD  - Surgical Advanced Technologies Lab, Center for Regenerative Medicine, Houston Methodist Research Institute, Houston 77030 USA
AD  - Department of Surgery, Houston Methodist Hospital, Houston, TX, 77030, USA
AD  - Surgical Advanced Technologies Lab, Center for Regenerative Medicine, Houston Methodist Research Institute, Houston, TX, 77030, USA
AD  - Weill Cornell Medical College, Cornell University, New York, NY, 10021, USA
U2  - PMID: 26578432.
DO  - 10.1007/s00464-015-4645-4
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105291837
T1  - Breast reconstruction with implants, tissue expanders and AlloDerm: predicting volume and maximizing the skin envelope in skin sparing mastectomies.
AU  - Haddock N
AU  - Levine J
Y1  - 2010/01//Jan/Feb2010
N1  - Accession Number: 105291837. Language: English. Entry Date: 20100305. Revision Date: 20150711. Publication Type: Journal Article; equations & formulas; pictorial; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Peer Reviewed; USA. Special Interest: Oncologic Care; Women's Health. NLM UID: 9505539. 
KW  - Breast Reconstruction
KW  - Surgery, Reconstructive -- Methods
KW  - Tissue Expansion -- Methods
KW  - Adult
KW  - Biocompatible Materials
KW  - Female
KW  - Human
KW  - Linear Regression
KW  - Record Review
KW  - Retrospective Design
SP  - 14
EP  - 19
JO  - Breast Journal
JF  - Breast Journal
JA  - BREAST J
VL  - 16
IS  - 1
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - AlloDerm has been used as a tissue supplement in conjunction with the pectoralis major muscle to provide full coverage over an implant in breast reconstruction. While this method of reconstruction has shown promising results there is little known on the relationship of AlloDerm size and potential immediate expansion volume. A retrospective chart review was completed evaluating all tissue expander or primary implant reconstructions using AlloDerm. Data recorded included: The type/size of implant/expander, dimensions of the AlloDerm used, initial fill volume, number of expansions and time period of expansion. Statistical analysis was completed with a linear regression model. AlloDerm was used on 49 patients (72 reconstructions). Thirty-four patients (50 reconstructions) underwent reconstruction with a tissue expander and 15 patients (22 reconstructions) underwent a single stage reconstruction with a permanent implant. The tissue expander volume filled (cc) could be predicted by 5 x surface area of AlloDerm (cm2) - 12 ( R2 = 0.62) and 80 x height of AlloDerm (cm) - 15 ( R2 = 0.59). The tissue expanders could be filled to an average of 75% of total size and required three to four injections in the postoperative period to reach full expansion. Obviously, a requirement for maximal implant expansion is an appropriate skin sparing mastectomy. There is a mathematical relationship between fill volume and surface area as well as height of AlloDerm used in breast reconstruction. This analysis provides a guideline for immediate implant expansion to surgeons using AlloDerm in reconstructive breast surgery.
SN  - 1075-122X
AD  - The Institute of Reconstructive Plastic Surgery, Division of Plastic Surgery, New York University Medical Center, 550 First Ave, TH169, New York, NY 10016
U2  - PMID: 19929887.
DO  - 10.1111/j.1524-4741.2009.00866.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 127039283
T1  - Fisioterapia em grupo na reabilitação funciona dos membros superiores de mulheres pós- mastectomia.
AU  - Mutti Tacani, Pascale
AU  - Nóbrega Batista, Persia Aline
AU  - Machado de Campos, Camila
AU  - Kasawara, Karina Tamy
AU  - Okano Gimenes, Rafaela
Y1  - 2013/01//Jan-Mar2013
N1  - Accession Number: 127039283. Language: Portuguese. Entry Date: 20180302. Revision Date: 20180313. Publication Type: Article; research; tables/charts. 
KW  - Rehabilitation -- Methods
KW  - Physical Therapy Assessment
KW  - Upper Extremity
KW  - Mastectomy
KW  - Human
KW  - Female
KW  - Breast Neoplasms
KW  - Exercise
KW  - Middle Age
KW  - Range of Motion
KW  - Data Analysis Software
KW  - Wilcoxon Rank Sum Test
SP  - 70
EP  - 75
JO  - Manual Therapy, Posturology & Rehabilitation Journal
JF  - Manual Therapy, Posturology & Rehabilitation Journal
VL  - 11
IS  - 51
PB  - Revista Terapia Manual
AB  - Introduction: Breast cancer is more common among women and can cause complications, which can be avoided by adopting an exercise program started early functional rehabilitation. Objective: This study aimed to investigate the effectiveness of physical therapy group in volume and range of motion of the upper limbs in women with mastectomy. Methods: The sample consisted of 10 patients with a mean age of 60.8 years, with unilateral or bilateral mastectomy. To obtain the data, the participants were examined on a range of motion (ROM) and the volume of the upper limbs, pre and post-treatment. To statistical analysis was used Wilcoxon test with significance level fixed at 5% (p<0.05). Results: It was observed significant difference in ROM of the shoulder during abduction left (p=0.047) and in the volume of the right upper limb (p=0.009). Conclusion: The study showed the effects of group physiotherapy on post-operative mastectomy, favoring an increase of the ROM for abduction left and reducing the volume of the right upper limp, with a positive influence on the functionality of the upper limp and thus the activities of daily living.
AB  - Introdução: O câncer de mama é mais comum entre as mulheres e pode ocasionar complicações, que podem ser evitadas com a adoção de um programa de exercícios de reabilitação funcional iniciado precocemente. Objetivo: Verificar a efetividade da fisioterapia em grupo na amplitude de movimento e volume dos membros superiores de mulheres mastectomizadas. Método: A amostra foi de 10 pacientes, com idade média de 60,8 anos, pós-mastectomia unilateral ou bilateral. Para obtenção dos dados, as participantes foram submetidas a uma avaliação da amplitude de movimento (ADM) e do volume dos membros superiores, no pré e pós-tratamento fisioterapêutico. Para análise estatística foi utilizado o teste de Wilcoxon com nível de significância fixado em 5% (p<0,05). Resultados: Observou-se diferença significante na ADM do ombro durante a abdução esquerda (p=0,047) e no volume do membro superior direito (p=0,009). Conclusão: O estudo apontou os efeitos da fisioterapia em grupo no pós-operatório de mastectomia, favorecendo um aumento da ADM para abdução esquerda e redução do volume do membro superior direito, com influência positiva na funcionalidade do membro superior e, consequentemente, nas atividades de vida diária.
SN  - 2236-5435
AD  - Fisioterapeuta. Docente do curso de fisioterapia do Centro Universitário São Camilo (CUSC), São Paulo, SP, Brasil
AD  - Fisioterapeuta. Graduada no Centro Universitário São Camilo (CUSC), São Paulo, SP, Brasil
AD  - Doutoranda pelo Departamento de Tocoginecologia da Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brasil
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DP  - EBSCOhost
DB  - ccm
ER  - 

ID  - 119802449
T1  - Host Integration of an Acellular Dermal Matrix: Braxon Mesh in Breast Reconstruction.
AU  - Iqbal, Fahad M.
AU  - Bhatnagar, Anjali
AU  - Vidya, Raghavan
Y1  - 2016/12//
N1  - Accession Number: 119802449. Language: English. Entry Date: 20170727. Revision Date: 20180121. Publication Type: case study; letter. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 100898731. 
KW  - Breast Neoplasms -- Surgery
KW  - Breast Reconstruction -- Equipment and Supplies
KW  - Breast Implants
KW  - Dermis
KW  - Female
SP  - e209
EP  - e211
JO  - Clinical Breast Cancer
JF  - Clinical Breast Cancer
JA  - CLIN BREAST CANCER
VL  - 16
IS  - 6
CY  - New York, New York
PB  - Elsevier B.V.
SN  - 1526-8209
AD  - ele University, Stoke-on-Trent, UK
AD  - Department of Pathology, New Cross Hospital, Wolverhampton, UK
AD  - Breast Unit, New Cross Hospital, Wolverhampton, UK
U2  - PMID: 27471076.
DO  - 10.1016/j.clbc.2016.06.009
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ER  - 

TY  - JOUR
ID  - 127250790
T1  - Early Outcomes Of Immediate Breast Reconstructions Using Acellular Dermal Matrix After Mastectomy For Breast Cancer.
AU  - Soumian, Soni
AU  - Marla, Sekhar
Y1  - 2017/12/02/2017 Supplement
N1  - Accession Number: 127250790. Language: English. Entry Date: In Process. Revision Date: 20180117. Publication Type: Article. Supplement Title: 2017 Supplement. Journal Subset: Asia; Biomedical. NLM UID: 101249598. 
SP  - S36
EP  - S36
JO  - Journal of Cancer Research & Therapeutics
JF  - Journal of Cancer Research & Therapeutics
JA  - J CANCER RES THER
VL  - 13
PB  - Wolters Kluwer India Pvt Ltd
SN  - 0973-1482
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ER  - 

TY  - JOUR
ID  - 104470776
T1  - Contributing Variables to Post Mastectomy Tissue Expander Infection.
AU  - Leyngold, Mark M.
AU  - Stutman, Ross L.
AU  - Khiabani, Kayvan T.
AU  - Shah, Himansu
AU  - Fong, Elvis
AU  - Ho, Chih-Hsiang
AU  - Zamboni, William A.
Y1  - 2012/07//Jul/Aug2012
N1  - Accession Number: 104470776. Language: English. Entry Date: 20120730. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Peer Reviewed; USA. Special Interest: Oncologic Care; Perioperative Care; Women's Health. NLM UID: 9505539. 
KW  - Mastectomy
KW  - Breast Reconstruction -- Adverse Effects
KW  - Postoperative Complications -- Etiology
KW  - Infection -- Etiology
KW  - Human
KW  - Female
KW  - Retrospective Design
KW  - Record Review
KW  - Logistic Regression
KW  - Descriptive Statistics
KW  - Odds Ratio
KW  - P-Value
KW  - Adult
KW  - Middle Age
KW  - Aged
KW  - ROC Curve
KW  - Data Analysis, Statistical
KW  - Data Analysis Software
KW  - Chi Square Test
KW  - Confidence Intervals
KW  - Infection -- Epidemiology
SP  - 351
EP  - 356
JO  - Breast Journal
JF  - Breast Journal
JA  - BREAST J
VL  - 18
IS  - 4
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Tissue expander breast reconstruction is a common post mastectomy breast procedure performed by plastic surgeons. The purpose of this study was to define the incidence of breast reconstruction prosthetic infection, relate patient characteristics with increased rate of infection, and analyze the influence of postoperative complications to expander/implant infection. A retrospective, single-institution chart review of 195 women with post mastectomy tissue expander/implant reconstructions performed from 2006 through 2008 was conducted. Total periprosthetic infection rate was calculated. Patient factors, operative technique, and noninfectious complications were analyzed and related to increased periprosthetic infection rate. A binary logistic regression model was fitted using periprosthetic infection as the dependent variable and 12 patient characteristics as independent variables, followed by a step-wise model for best fit with a limited number of independent variables. The overall periprosthetic infection rate per patient over the 2 year period was 5.1%. The incidence of periprosthetic infection per reconstructed breast was 3.2%. Odds ratio estimates indicated that the presence of cellulitis increased the odds of periprosthetic infection more than 200 times (p = <0.0001), and inpatient procedures increased the odds 16 times (p = 0.02). Other variables (i.e., age > 65, DM, flap necrosis, smoking, dehiscence, AlloDerm, etc) failed to reach statistical significance (p > 0.05). Postoperative breast cellulitis and inpatient status appear to be significant risk factors for increased periprosthetic infection. No significant increase in periprosthetic infection rate was noted with other variables in this model.
SN  - 1075-122X
AD  - Division of Plastic Surgery, Department of Surgery, University of Nevada School of Medicine, Las Vegas, Nevada
AD  - Department of Mathematics, University of Nevada, Las Vegas, Nevada
U2  - PMID: 22616636.
DO  - 10.1111/j.1524-4741.2012.01253.x
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 104189133
T1  - Use of porcine acellular dermal matrix in revisionary cosmetic breast augmentation.
AU  - Pozner, Jason N
AU  - White, Jeremy B
AU  - Newman, Martin I
Y1  - 2013/07//
N1  - Accession Number: 104189133. Language: English. Entry Date: 20131108. Revision Date: 20161117. Publication Type: journal article; research. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
KW  - Breast Implants -- Adverse Effects
KW  - Breast Reconstruction -- Adverse Effects
KW  - Surgery, Reconstructive -- Methods
KW  - Dermis
KW  - Adult
KW  - Aged
KW  - Animals
KW  - Prospective Studies
KW  - Esthetics
KW  - Female
KW  - Graft Survival
KW  - Human
KW  - Foreign-Body Reaction -- Surgery
KW  - Breast Reconstruction -- Methods
KW  - Middle Age
KW  - Postoperative Complications -- Diagnosis
KW  - Postoperative Complications -- Surgery
KW  - Reoperation -- Methods
KW  - Retrospective Design
KW  - Risk Assessment
KW  - Surgical Flaps
KW  - Swine
KW  - Treatment Outcomes
KW  - Young Adult
SP  - 681
EP  - 690
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 33
IS  - 5
PB  - Oxford University Press / USA
AB  - Background: Aesthetic breast augmentation can be fraught with postoperative complications, particularly capsular contracture (CC), skin surface irregularities, and implant or inframammary fold malposition. Similar complications have been addressed successfully in reconstructive breast surgery with acellular dermal matrix (ADM) products.Objective: The authors present their initial experience with porcine ADM (PADM) in aesthetic breast augmentation.Methods: Retrospective chart review was performed for 93 consecutive patients (179 breasts) who underwent revisionary cosmetic breast augmentation with or without mastopexy between May 2009 and September 2012. Porcine ADM (Strattice; Lifecell Corp, Branchburg, New Jersey) was placed bilaterally in 74 patients and unilaterally in 19 patients. All patients were operated upon by 1 surgeon (J.N.P.). Product use description and complications were recorded, including infection, extrusion, CC, and implant malposition.Results: Average follow-up was 12 months (range, 1-39 months). There were 2 major complications (1.6% of breasts): an infection in 1 breast that required implant explantation approximately 2 weeks postoperatively and an extrusion that required PADM removal. Two additional patients had high-riding implants resulting from folded PADM that required revision; both cases were corrected by excising the folded PADM segment. Seven other patients required office procedures to correct minor imperfections. Two CC recurrences were suspected (1 patient) in the 76 breasts that underwent capsulectomy and PADM placement.Conclusions: Porcine ADM demonstrated great utility as an adjunct in revisionary cosmetic breast surgery. The product helped to provide good aesthetic outcomes with low complication rates. Prospective, randomized trials may prove helpful in defining the role of PADM further in these challenging cases.
SN  - 1090-820X
AD  - Dr Pozner is an adjunct clinical faculty member in the Department of Plastic Surgery at Cleveland Clinic Florida, Weston, Florida.
U2  - PMID: 23813397.
DO  - 10.1177/1090820X13491279
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 104287832
T1  - Resistance of acellular dermal matrix materials to microbial penetration.
AU  - Fahrenbach, Elizabeth N
AU  - Qi, Chao
AU  - Ibrahim, Omer
AU  - Kim, John Y
AU  - Alam, Murad
Y1  - 2013/05//
N1  - Accession Number: 104287832. Language: English. Entry Date: 20130816. Revision Date: 20160526. Publication Type: journal article; research. Journal Subset: Biomedical; USA. NLM UID: 101589530. 
KW  - Materials Testing
KW  - Biocompatible Materials -- Adverse Effects
KW  - Candida Albicans
KW  - Collagen
KW  - Human
KW  - Pseudomonas
KW  - Staphylococcus Aureus
KW  - Streptococcus
SP  - 571
EP  - 575
JO  - JAMA Dermatology
JF  - JAMA Dermatology
JA  - JAMA DERMATOL
VL  - 149
IS  - 5
CY  - Chicago, Illinois
PB  - American Medical Association
AB  - Importance: Acellular dermal matrices have many current and potential applications, but their long-term safety has not been extensively studied. In particular, limited information exists regarding such materials' resistance to infection.Objective: To assess the resistance to microbial penetration of common acellular dermal matrix materials used in reconstruction after skin cancer excision, treatment of chronic ulcers and burns, breast reconstruction, hernia repairs, and other applications.Design: Comparative in vitro study of 4 commercially available dermal substitutes for their ability to act as barriers to penetration by common skin pathogens.Setting: University-based dermatology and plastic surgery departments and a hospital microbiology laboratory.Materials: Four commercially available dermal substitutes, including AlloDerm (LifeCell), FlexHD (Musculoskeletal Transplant Foundation), Strattice (LifeCell), and NeoForm (Mentor Corporation).Intervention: We tested the 4 dermal matrix materials with the following 4 organisms commonly implicated in wound infections: Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pyogenes, and Candida albicans. Each material was inoculated with the same concentration of each pathogen.Main Outcome Measure: The number of bacterial colonies grown on blood agar plates.Results: AlloDerm and rehydrated FlexHD were found to be the best barriers to penetration by P. aeruginosa. AlloDerm, FlexHD, and Strattice also prevented penetration by S. aureus and S. pyogenes; NeoForm was less effective in withstanding these organisms. The results of this study were inconclusive with regard to C. albicans penetration.Conclusions and Relevance: Three of the 4 commonly used acellular dermal matrix materials are resistant to in vitro penetration by S. aureus and S. pyogenes and partially resistant to P. aeruginosa. Resistance to fungal pathogens is uncertain. Antimicrobial differences across matrix materials may influence their selection for particular uses, such as treatment of refractory leg ulcers or reconstruction after skin cancer excision.
SN  - 2168-6068
AD  - Department of Medicine, Loyola-Stritch School of Medicine, Maywood, Illinois, USA.
U2  - PMID: 23426233.
DO  - 10.1001/jamadermatol.2013.1741
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 109726748
T1  - The efficacy of botulinum toxin A in post-mastectomy breast reconstruction: a pilot study.
AU  - Gabriel, Allen
AU  - Champaneria, Manish C
AU  - Maxwell, G Patrick
Y1  - 2015/05//May/Jun2015
N1  - Accession Number: 109726748. Language: English. Entry Date: 20150923. Revision Date: 20161118. Publication Type: journal article; research; randomized controlled trial. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
SP  - 402
EP  - 409
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 35
IS  - 4
PB  - Oxford University Press / USA
AB  - Background: Botulinum toxin A has been successfully used in a variety of areas to temporarily obliterate muscle mobility for either functional or aesthetic gain. Tissue expander-based breast reconstruction has been plagued with pain and discomfort.Objective: The purpose of this pilot study was to evaluate the role of a neurotoxin (Botulinum toxin A) in expander-based breast reconstruction.Methods: Thirty patients underwent mastectomies with immediate expander or acellular dermal matrix reconstruction. The neurotoxin group (n = 15) received 40 units of neurotoxin (Botulinum toxin A, Allergan, Inc, Irvine, CA) into each pectoralis major muscle through 4 serial injections and the placebo group (n = 15) received 4 serial injections of 0.9% NaCl. All patients were followed over 1 year, and patient demographics, VAS (visual analog score), laterality, office visits, amount of expansion and number of times to full expansion, and amount of narcotics required were recorded. Statistical significance was considered as p < .05.Results: There were no significant differences between the two groups in terms of age, laterality, expander size, or complications (p = .46-.66). There was a significant difference between the two groups in the VAS score, demonstrating decreased pain in the neurotoxin group (p < .05). In addition, there was a significant increase in the volume of expansion per visit in the neurotoxin group as compared to the placebo group (p < .05). There was no significant difference in narcotic use in the first 3 days after surgery; however, there was a significant decrease in use of narcotics from 7 to 45 days in the neurotoxin group (p < .05). There were no complications associated with the use of the neurotoxin.Conclusions: The infiltration of the pectoralis major muscle with neurotoxin in immediate, expander-based reconstruction may be beneficial in reducing pain and expediting expansions.
SN  - 1090-820X
U2  - PMID: 25825421.
DO  - 10.1093/asj/sjv040
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 109692161
T1  - Further evidence that human acellular dermal matrix decreases inflammatory markers of capsule formation in implant-based breast reconstruction.
AU  - Leong, Mimi
AU  - Basu, C Bob
AU  - Hicks, M John
Y1  - 2015/01//
N1  - Accession Number: 109692161. Language: English. Entry Date: 20150605. Revision Date: 20161118. Publication Type: journal article. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
SP  - 40
EP  - 47
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 35
IS  - 1
PB  - Oxford University Press / USA
AB  - Background: Human acellular dermal matrix (HADM; previously termed "acellular cadaveric dermis") may limit inflammatory changes believed to play a role in capsular contracture, a common complication of implant-based breast reconstruction.Objectives: Differences between HADM and native breast capsule specimens were evaluated by immunohistochemical analysis of key inflammatory markers involved in capsule formation.Methods: Twenty consecutive patients underwent immediate, 2-stage, implant-based breast reconstruction with dual-plane HADM. During tissue expander-implant exchange, full-thickness biopsies of biointegrated HADM and native breast capsule (internal control) from the tissue-expander envelope were obtained. Immunohistochemical analysis was performed for endothelial cells (CD31), B cells (CD20), T cells (CD3), macrophages (CD68), collagen I and III, and myofibroblasts (α-smooth muscle actin). Observed levels of marker labeling were semiquantitatively scored from 0 (none) to 3 (severe) by a blinded histopathologist and were statistically analyzed with the Wilcoxon rank sum test.Results: A bilateral sample was obtained from 1 patient; all other samples were unilateral. Compared with capsule samples from native breast tissue, HADM samples had significantly lower levels of all inflammatory markers (P < .001).Conclusions: These lower levels of inflammatory markers support previous evidence that HADM may inhibit inflammatory and profibrotic signaling characteristics of breast capsule development and decrease the risk of capsular contracture. Further investigation is needed to determine the mechanism by which HADM inhibits these inflammatory cells, whether HADM reduces the incidence of breast capsular contracture, and if so, the longevity of this effect.
SN  - 1090-820X
U2  - PMID: 25568233.
DO  - 10.1093/asj/sju014
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 109602675
T1  - Nipple-Sparing Mastectomy via an Inframammary Fold Incision with Implant-Based Reconstruction in Patients with Prior Cosmetic Breast Surgery.
AU  - Dent, Briar L
AU  - Cordeiro, Christina N
AU  - Small, Kevin
AU  - Clemons, Jessica A
AU  - Kessler, Evan G
AU  - Swistel, Alexander
AU  - Talmor, Mia
Y1  - 2015/07//2015 Jul
N1  - Accession Number: 109602675. Language: English. Entry Date: 20150923. Revision Date: 20161118. Publication Type: journal article. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
SP  - 548
EP  - 557
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 35
IS  - 5
PB  - Oxford University Press / USA
AB  - Background: Nipple-sparing mastectomy through an inframammary fold incision (NSM-IMF) with implant-based reconstruction (IBR) is a cosmetically preferable approach to breast cancer treatment in appropriate candidates. However, patients who have undergone prior cosmetic breast surgery (CBS) may be at increased risk for postoperative complications secondary to existing surgical scars.Objective: To assess whether prior CBS increases the risk of complications following NSM-IMF with IBR.Methods: A retrospective chart review was conducted for 398 NSM-IMFs with IBR performed between July 2006 and December 2013. CBS cases were identified. Outcomes were reviewed.Results: Of 398 NSM-IMF cases, 41 had prior CBS: 24 augmentations, 12 reductions, three mastopexies, and two augmentation mastopexies. NSM-IMF was performed an average of 8 years following CBS. CBS cases had lower BMIs (P = .040), more breast tissue resected (P = .021), wider breast bases (P = .0002), more single-stage reconstructions (P < .0001), more ADM use (P < .0001), and larger permanent implants (P = .0051) than those without CBS. Postoperatively, CBS cases had higher rates of mastectomy flap ischemia (P = .0392) and hematoma (P = .0335). Among CBS cases, single-stage reconstruction was associated with increased full-thickness flap ischemia (P = .0066). Compared to prior augmentation cases, prior reduction/mastopexy cases had higher rates of capsular contracture (P = .0409) and seroma (P = .0226).Conclusions: This series is the largest to date to evaluate the success of NSM-IMF with IBR in CBS patients. These women should be cautiously considered for IBR, particularly in the setting of single-stage reconstruction.Level Of Evidence: 4 Therapeutic.
SN  - 1090-820X
AD  - Dr Dent is a Resident and Dr Talmor is an Attending Surgeon and Associate Professor of Clinical Surgery, Division of Plastic Surgery, Department of Surgery, New York-Presbyterian Hospital/Weill Cornell Medical College, New York, New York. Dr Cordeiro is a Resident, Department of Gynecology and Obstetrics, The Johns Hopkins University School of Medicine, Baltimore, Maryland. Dr Small is a Fellow, Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, Texas. Ms. Clemons is a Medical Student, Weill Cornell Medical College, Cornell University, New York, New York. Dr Kessler is a Resident, Department of Surgery, University at Buffalo, Buffalo General Medical Center, Buffalo, New York. Dr Swistel is an Attending Surgeon and Associate Professor of Clinical Surgery, Division of Breast Surgery, Department of Surgery, New York-Presbyterian Hospital/Weill Cornell Medical College, New York, New York.
U2  - PMID: 25911626.
DO  - 10.1093/asj/sju158
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 104256520
T1  - Efficacy of acellular dermal matrices in revisionary aesthetic breast surgery: a 6-year experience.
AU  - Maxwell, G Patrick
AU  - Gabriel, Allen
Y1  - 2013/03//
N1  - Accession Number: 104256520. Language: English. Entry Date: 20131011. Revision Date: 20161117. Publication Type: journal article; research. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
KW  - Breast
KW  - Esthetics
KW  - Breast Reconstruction
KW  - Postoperative Complications
KW  - Skin Transplantation
KW  - Skin Transplantation -- Adverse Effects
KW  - Adult
KW  - Aged
KW  - Breast Implants -- Adverse Effects
KW  - Female
KW  - Human
KW  - Breast Reconstruction -- Methods
KW  - Middle Age
KW  - Postoperative Complications -- Etiology
KW  - Reoperation
KW  - Retrospective Design
KW  - Suture Techniques
KW  - Time Factors
KW  - Treatment Outcomes
KW  - Young Adult
SP  - 389
EP  - 399
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 33
IS  - 3
PB  - Oxford University Press / USA
AB  - Background: Augmentation mammaplasty and augmentation mastopexy are associated with a substantial primary and secondary revision rate. Capsular contracture (CC), implant malposition, ptosis, asymmetry, and rippling are the main reasons for revisionary surgery in these patients. Traditional corrective techniques have not been completely reliable in preventing or treating these complications. Recently, acellular dermal matrices (ADM) have been used to assist with revisionary surgery with promising results.Objective: The authors review their 6-year experience using ADM for revisionary surgery in aesthetic patients and evaluate long-term outcomes with this approach.Methods: Patients who underwent revisionary breast augmentation or augmentation mastopexy with ADM in conjunction with standard techniques over a 6-year period between October 2005 and December 2011 were retrospectively reviewed. Only patients with at least 1 year of follow-up were included in the analysis.Results: A total of 197 revisions were performed (197 patients). Reasons for revision included CC (61.8%), implant malposition (31.2%), rippling (4.8%), ptosis (4.8%), implant exposure (1.6%), and breast wound (0.5%). The mean ± SD follow-up period was 3.1 ± 1.1 years (range, 0.1-6.1 years). The complication rate was 4.8%, including Baker grade III/IV CC (1.6%), infection (1.6%), implant malposition (0.5%), hematoma (0.5%), and seroma (0.5%). Most (98%) revisions were successful, with no recurrence of the presenting complaint.Conclusions: The use of ADM in conjunction with standard techniques for the reinforcement of weak tissue in revision augmentation and augmentation mastopexy patients appears to be effective.
SN  - 1090-820X
AD  - Department of Plastic Surgery, Loma Linda University Medical Center, Loma Linda, California.
U2  - PMID: 23439064.
DO  - 10.1177/1090820X13478967
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 105720759
T1  - Correction of chest wall deformity after implant-based breast reconstruction using poly-l-lactic acid (Sculptra)
AU  - Schulman MR
AU  - Lipper J
AU  - Skolnik RA
Y1  - 2008/01//
N1  - Accession Number: 105720759. Language: English. Entry Date: 20080523. Revision Date: 20150711. Publication Type: Journal Article; case study; pictorial. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Peer Reviewed; USA. NLM UID: 9505539. 
KW  - Breast Implants
KW  - Breast Reconstruction
KW  - Female
KW  - Middle Age
SP  - 92
EP  - 96
JO  - Breast Journal
JF  - Breast Journal
JA  - BREAST J
VL  - 14
IS  - 1
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Implant-based breast reconstruction after mastectomy offers excellent cosmetic results in select individuals. However, this technique may result in a step-off between the implant and the soft tissue of the chest wall, which can be problematic in the extremely thin patient. Also, the removal of soft tissue can result in prominent ribs and visible intercostal spaces. A number of surgical options exist to correct these defects and include dermal grafts, flap reconstruction, and implant exchange. We present the case of a thin woman with a persistent 'step-off' deformity and visible intercostal spaces after mastectomy and two-stage implant reconstruction. Placement of acellular cadaveric dermis (Alloderm) failed to improve the appearance of her chest wall. The authors utilized poly-L-lactic acid (Sculptra) for soft tissue augmentation of her chest wall with significant esthetic improvement. This novel use of poly-L-lactic acid offers a useful alternative to invasive surgical procedures to correct a soft tissue deformity of the chest wall. While poly-L-lactic acid has recently gained popularity for soft tissue augmentation of the face, to date, no reports in the literature exist describing its use in the correction of difficult chest wall defects after mastectomy and implant reconstruction. We maintain that poly-L-lactic acid may also be useful to improve a variety of soft tissue deformities of the breast.
SN  - 1075-122X
AD  - Division of Plastic and Reconstructive Surgery, The Mount Sinai School of Medicine and The Mount Sinai Hospital, New York, New York, USA. matthewschulman.md@gmail.com
U2  - PMID: 18186871.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105720759&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109644823
T1  - Reconstruction Department. A Review of the Use of Acellular Dermal Matrices in Postmastectomy Immediate Breast Reconstruction.
AU  - Chao, Albert H.
Y1  - 2015/07//Jul-Sep2015
N1  - Accession Number: 109644823. Language: English. Entry Date: 20150923. Revision Date: 20150923. Publication Type: Journal Article. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 8403490. 
SP  - 131
EP  - 136
JO  - Plastic Surgical Nursing
JF  - Plastic Surgical Nursing
JA  - PLAST SURG NURS
VL  - 35
IS  - 3
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
SN  - 0741-5206
AD  - Assistant Professor, Department of Plastic Surgery, Ohio State University
DO  - 10.1097/PSN.0000000000000103
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109644823&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 123768178
T1  - A Guide to Prepectoral Breast Reconstruction: A New Dimension to Implant-based Breast Reconstruction.
AU  - Vidya, Raghavan
AU  - Iqbal, Fahad Mujtaba
Y1  - 2017/07//
N1  - Accession Number: 123768178. Language: English. Entry Date: 20180413. Revision Date: 20180413. Publication Type: journal article; review. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Instrumentation: Short Portable Mental Status Questionnaire (SPMSQ) (Pfeiffer). NLM UID: 100898731. 
KW  - Breast Implants
KW  - Therapeutics -- Methods
KW  - Pectoralis Muscles
KW  - Dermis
KW  - Breast Neoplasms -- Surgery
KW  - Breast Reconstruction
KW  - Breast Neoplasms -- Pathology
KW  - Female
KW  - Short Portable Mental Status Questionnaire
SP  - 266
EP  - 271
JO  - Clinical Breast Cancer
JF  - Clinical Breast Cancer
JA  - CLIN BREAST CANCER
VL  - 17
IS  - 4
CY  - New York, New York
PB  - Elsevier B.V.
AB  - Acellular dermal matrix has revolutionized implant-based breast reconstruction. Breast reconstruction has evolved from the traditional submuscular to the new prepectoral implant based (also known as muscle-sparing) reconstruction. The new technique is emerging as a highly popular surgery owing to its more minimal approach. We conducted a narrative review to guide prepectoral breast reconstruction, highlighting the technique, the need for appropriate patient selection, and areas for further research. We show that prepectoral breast reconstruction is safe, feasible, and has excellent short-term outcomes (cosmesis and patient satisfaction). Its main advantages are that it avoids animation deformity, prevents shoulder dysfunction, and has a lower incidence of capsular contracture. Selection for the prepectoral technique is dependent on patient factors (eg, body mass index, lifestyle), breast size, flap assessment, and adjuvant radiotherapy. Whereas the initial short-term results are promising, long-term outcomes are yet to be reported and is an area that requires further research.
SN  - 1526-8209
AD  - Birmingham University, Birmingham, UK
AD  - Breast Unit, New Cross Hospital, Wolverhampton, UK
AD  - Medical School, Keele University, Stoke-on-Trent, Staffordshire, UK
U2  - PMID: 28190760.
DO  - 10.1016/j.clbc.2016.11.009
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103819412
T1  - Non-cross-linked porcine acellular dermal matrix in revision breast surgery: long-term outcomes and safety with neopectoral pockets.
AU  - Maxwell, G Patrick
AU  - Gabriel, Allen
Y1  - 2014/05//
N1  - Accession Number: 103819412. Language: English. Entry Date: 20150116. Revision Date: 20161118. Publication Type: journal article; research. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
KW  - Dermis
KW  - Breast -- Surgery
KW  - Breast Implants -- Adverse Effects
KW  - Collagen -- Therapeutic Use
KW  - Postoperative Complications -- Surgery
KW  - Adult
KW  - Aged
KW  - Female
KW  - Human
KW  - Middle Age
KW  - Postoperative Complications -- Diagnosis
KW  - Postoperative Complications -- Etiology
KW  - Reoperation
KW  - Retrospective Design
KW  - Time Factors
KW  - Treatment Outcomes
KW  - Young Adult
SP  - 551
EP  - 559
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 34
IS  - 4
PB  - Oxford University Press / USA
AB  - Background: Revision breast surgery represents a significant problem among patients who have undergone augmentation mammaplasty. Current techniques do not adequately prevent recurrence, thus requiring novel approaches, including placement of Strattice (LifeCell, Branchburg, New Jersey), a non-cross-linked porcine acellular dermal matrix, to minimize recurrence.Objective: The authors review their experience and long-term outcomes with placement of Strattice in revision breast surgery patients who underwent previous augmentation mammaplasty.Methods: All patients in the authors' practice with a previous history of augmentation mammaplasty who underwent revision breast surgery with placement of Strattice between January 2007 and December 2011, and who had a minimum of 12 months of follow-up, were included in this retrospective study. A total of 106 patients met the study's inclusion criteria.Results: Average patient age was 42.3 years and average follow-up time was 3.1 years. Indications for revision surgery included capsular contracture (51.9%), implant malposition (38.7%), and ptosis (8.5%); approximately 40% had ≥1 previous attempts to correct the presenting complaint. Revision surgery included creation of neosubpectoral pockets with retention of previous noncalcified capsules in 81% of patients with subpectoral implants. Presenting complaints were successfully resolved in all patients. The overall complication rate was 0.9%.Conclusions: Adding Strattice to traditional revision surgery procedures results in reliable, durable repair of the presenting complaint with minimal associated complications. Treatment with Strattice in conjunction with noncalcified capsules retained during site change also appears to be safe. The data support a role for Strattice in revision breast surgery for patients who have undergone previous augmentation mammaplasty.
SN  - 1090-820X
AD  - Department of Plastic Surgery, Loma Linda University Medical Center, Loma Linda, California.
U2  - PMID: 24692599.
DO  - 10.1177/1090820X14528207
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109789098
T1  - New Deep Dermal ADM Incorporates Well in Case Series of Complex Breast Reconstruction Patients.
AU  - Wilson, Henry Benjamin
Y1  - 2015/05/22/
N1  - Accession Number: 109789098. Language: English. Entry Date: 20150828. Revision Date: 20151031. Publication Type: journal article; research. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 2985248R. 
KW  - Dermis
KW  - Breast Neoplasms -- Surgery
KW  - Breast Reconstruction -- Methods
KW  - Adult
KW  - Collagen
KW  - Female
KW  - Human
KW  - Length of Stay
KW  - Middle Age
KW  - Patient Satisfaction
KW  - Postoperative Care
KW  - Prosthesis-Related Infections -- Epidemiology
SP  - e745
EP  - e745
JO  - Medicine
JF  - Medicine
JA  - MEDICINE
VL  - 94
IS  - 20
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - Breast cancer patients with significant comorbidities present reconstructive challenges due to a predictably high complication rate. During expander-based breast reconstruction, human acellular dermal matrix (ADM) is often used to prevent pectoralis muscle retraction, facilitate early expansion, and improve cosmetic outcome. Device infection and chronic seroma have been correlated to the addition of the graft by some large database reports but not others. This study describes the first reported experience with a new deep dermal ADM, FlexHD® Pliable™ (MTF, Edison, NJ). Sixteen breasts in 10 consecutive patients identified retrospectively and followed prospectively had immediate expander-based breast reconstruction utilizing the new ADM. Patient comorbidities were catalogued, complications were recorded, and overall reconstructive success was assessed. At implant exchange, the ADM was examined for tissue ingrowth and biopsied for histologic examination. All 16 breasts had successful reconstructions. Two breasts (12.5%) developed device infection, requiring removal and later replacement of the expander. One breast (6.7%) developed chronic seroma, also requiring expander removal and later replacement. All the complicated patients had significant comorbidities, including obesity in all 3. At expander removal, the FlexHD Pliable showed near-complete visual tissue incorporation in 14 of 16 breasts (88%). This case series demonstrates significant reconstructive success in challenging patients utilizing a novel ADM. Visual and histologic assessment of tissue ingrowth into the graft suggests the high rate of complication may be due to patient comorbidities rather than addition of ADM. Additional experience is needed to confirm and the study is ongoing.
SN  - 0025-7974
U2  - PMID: 26020380.
DO  - 10.1097/MD.0000000000000745
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109789098&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103819407
T1  - Nipple-areolar complex ischemia after nipple-sparing mastectomy with immediate implant-based reconstruction: risk factors and the success of conservative treatment.
AU  - Dent, Briar L
AU  - Small, Kevin
AU  - Swistel, Alexander
AU  - Talmor, Mia
Y1  - 2014/05//
N1  - Accession Number: 103819407. Language: English. Entry Date: 20150116. Revision Date: 20161118. Publication Type: journal article; research. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
KW  - Breast Implants -- Adverse Effects
KW  - Ischemia -- Etiology
KW  - Mastectomy -- Adverse Effects
KW  - Nipples -- Blood Supply
KW  - Nipples -- Surgery
KW  - Administration, Transcutaneous
KW  - Adult
KW  - Aged
KW  - Antibiotics -- Administration and Dosage
KW  - Bacitracin -- Administration and Dosage
KW  - Female
KW  - Human
KW  - Ischemia -- Diagnosis
KW  - Ischemia -- Drug Therapy
KW  - Middle Age
KW  - Ointments
KW  - Retrospective Design
KW  - Risk Factors
KW  - Time Factors
KW  - Treatment Outcomes
SP  - 560
EP  - 570
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 34
IS  - 4
PB  - Oxford University Press / USA
AB  - Background: Nipple-sparing mastectomy performed via an inframammary fold incision with implant-based reconstruction is an oncologically safe procedure that provides excellent cosmesis.Objectives: The authors report their experience with conservative treatment of postoperative nipple-areolar complex (NAC) ischemia and an analysis of risk factors for NAC ischemia and conservative treatment failure.Methods: A retrospective chart review was conducted of 318 nipple-sparing mastectomies performed through inframammary fold incisions with implant-based reconstruction between July 2006 and October 2012. NAC dressings consisted of topical nitroglycerin, external warming for 24 hours, antibacterial petrolatum gauze, and a loose bra for 1 week. Patients were monitored for NAC ischemia as the primary endpoint. NAC ischemia was treated with bacitracin ointment. In cases of full-thickness ischemia, expanders were also partially deflated.Results: Partial- and full-thickness NAC ischemia occurred in 44 (13.8%) and 21 (6.6%) cases, respectively. All partial- and 17 full-thickness cases resolved with conservative treatment. Of these, 7 partial- and 2 full-thickness cases suffered residual depigmentation. Four full-thickness cases required operative debridement. Factors associated with NAC ischemia included increasing age (P = .035), higher body mass index (P = .0009), greater breast volume (P = .0023), and diabetes (P = .0046). Factors associated with conservative treatment failure included increasing age (P < .0001), higher body mass index (P = .014), greater breast volume (P = .020), smoking (P = .0449), acellular dermal matrix use (P < .0001), and single-stage reconstruction (P = .0090).Conclusions: Postoperative NAC ischemia can be effectively managed conservatively to preserve cosmesis and implant viability. Knowledge of risk factors for NAC ischemia and conservative treatment failure may improve future patient counseling and outcomes.
SN  - 1090-820X
AD  - Department of Surgery at New York-Presbyterian Hospital/Weill Cornell Medical College, New York, New York.
U2  - PMID: 24682442.
DO  - 10.1177/1090820X14528352
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103819407&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 121173033
T1  - 217 - Mesh versus acellular dermal matrix in immediate implant based breast reconstruction – a prospective randomized trial...ECCO: 2017 European Cancer Congress 27 January 2017 - 30 January 2017.
AU  - Gschwantler-Kaulich, E.
AU  - Schrenk, P.
AU  - Bjelic-Radisic, V.
AU  - Unterrieder, K.
AU  - Leser, C.
AU  - Fink-Retter, A.
AU  - Salama, M.
AU  - Singer, C.
Y1  - 2017/02/02/Feb2017 Supplement 1
N1  - Accession Number: 121173033. Language: English. Entry Date: 20170217. Revision Date: 20170217. Publication Type: Article; abstract; research. Supplement Title: Feb2017 Supplement 1. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Special Interest: Oncologic Care; Perioperative Care. NLM UID: 9005373. 
KW  - Surgical Mesh -- Utilization
KW  - Breast Implants
KW  - Breast Neoplasms -- Surgery
KW  - Breast Reconstruction -- Methods
KW  - Human
KW  - Random Sample
KW  - Prospective Studies
KW  - Treatment Outcomes
KW  - Comparative Studies
SP  - S30
EP  - S30
JO  - European Journal of Cancer
JF  - European Journal of Cancer
JA  - EUR J CANCER
VL  - 72
PB  - Pergamon Press - An Imprint of Elsevier Science
SN  - 0959-8049
DO  - 10.1016/S0959-8049(17)30176-4
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104854722
T1  - Long-term histologic and mechanical results of a Permacol™ abdominal wall explant.
AU  - O'Brien JA
AU  - Ignotz R
AU  - Montilla R
AU  - Broderick GB
AU  - Christakis A
AU  - Dunn RM
AU  - O'Brien, J A
AU  - Ignotz, R
AU  - Montilla, R
AU  - Broderick, G B
AU  - Christakis, A
AU  - Dunn, R M
Y1  - 2011/04//
N1  - Accession Number: 104854722. Language: English. Entry Date: 20110902. Revision Date: 20171021. Publication Type: journal article; case study. Journal Subset: Biomedical; Blind Peer Reviewed; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. NLM UID: 9715168. 
KW  - Abdomen -- Pathology
KW  - Abdomen -- Surgery
KW  - Biocompatible Materials
KW  - Collagen -- Physiology
KW  - Hematoma -- Surgery
KW  - Collagen
KW  - Collagen -- Analysis
KW  - Proteins -- Analysis
KW  - Female
KW  - Fibroblasts -- Physiology
KW  - Immunohistochemistry
KW  - Materials Testing
KW  - Middle Age
KW  - Tensile Strength
SP  - 211
EP  - 215
JO  - Hernia
JF  - Hernia
JA  - HERNIA
VL  - 15
IS  - 2
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
AB  - Purpose: We hypothesize that Permacol™ may allow controlled integration over time while providing long-term mechanical stability and native tissue remodeling. The purpose of this report is to investigate these properties in an explanted piece of Permacol™ after 2 years in vivo.Methods: A 62-year-old female presented with a complex abdominal wall history having undergone a transverse rectus abdominis musculocutaneous (TRAM) flap breast reconstruction 10 years ago, followed by an abdominal wall repair with Marlex™ mesh for weakness 3 years later. Two years ago, she developed an abdominal bulge repaired with a Permacol™ overlay. Twenty-three months postoperatively, she presented with abdominal distension. Computed tomography (CT) scanning demonstrated a fluid collection behind the Permacol™. She underwent incision and drainage of the hematoma/bursa and quilting repair of the abdominal wall. A 1 × 6-cm Permacol™ section was resected as part of closure. Histology, immunohistochemistry, and mechanical testing of the Permacol™ explant were performed.Results: Histology showed fibroblast and blood vessel ingrowth with no cellular infiltrates reflective of inflammation. Immunohistochemistry for human-specific collagen types I and III and elastin detected staining throughout. Sections stained with non-specific control antibody exhibited no discernable staining. Elastin highlighted blood vessels. Native Permacol™ had a breaking strength of ~20 N, while for explanted Permacol™, it was ~33 N.Conclusions: Permacol™ maintained durability while allowing vascular ingrowth without residual inflammation. Explant demonstrated integration with human collagen and elastin remodeling throughout. Increase in mechanical strength may reflect newly synthesized collagen and elastin. These histologic findings and clinical result support the use of Permacol™ in complex abdominal wall reconstruction.
SN  - 1265-4906
AD  - Department of Surgery, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA. Julie.O'
AD  - Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA, Julie.O'Brien@umassmemorial.org.
U2  - PMID: 20091328.
DO  - 10.1007/s10029-010-0628-5
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105255135
T1  - Use of the acellular dermal matrix in revisionary aesthetic breast surgery.
AU  - Maxwell GP
AU  - Gabriel A
AU  - Maxwell, G Patrick
AU  - Gabriel, Allen
Y1  - 2009/11//
N1  - Accession Number: 105255135. Language: English. Entry Date: 20100402. Revision Date: 20161117. Publication Type: journal article; research. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
KW  - Breast Implants -- Adverse Effects
KW  - Breast Implants -- Methods
KW  - Breast Implants
KW  - Collagen -- Therapeutic Use
KW  - Postoperative Complications -- Surgery
KW  - Adult
KW  - Female
KW  - Prospective Studies
KW  - Human
KW  - Medical Illustration
KW  - Postoperative Complications -- Etiology
KW  - Reoperation
KW  - Retrospective Design
KW  - Silicones
KW  - Suture Techniques
KW  - Treatment Outcomes
SP  - 485
EP  - 493
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 29
IS  - 6
PB  - Oxford University Press / USA
AB  - Background: Revisionary augmentation and revision of augmentation mastopexy are of considerable interest to plastic surgeons who perform breast surgery because of the procedures' complexity. In these cases, surgeons are faced with either thinned breast tissues resulting from large breast implants with tissue stretch or encapsulation caused by excessive scarring. To our knowledge, there are currently no large-series studies describing the use of acellular dermal matrices (ADM) in cosmetic breast surgery.Objective: The authors describe the use of the ADM in revisionary breast surgery to establish the aesthetic breast form.Methods: A retrospective chart review was conducted of 78 consecutive patients who underwent revisionary breast augmentation and augmentation mastopexies with ADM during a period of just over two years (October 2005 to January 2008). Data collected included patient characteristics, complications, outcomes, and reoperation rates.Results: Seventy-eight procedures were performed with ADM during the two-year period, with a minimum of 12 months of follow-up. There were two complications requiring reoperations for a hematoma and implant malposition, respectively. There were no Baker III or IV capsular contractures at one year postprocedure.Conclusions: Revisionary augmentation and revision of augmentation mastopexy are commonly performed procedures and they have a significantly higher complication rate than primary procedures. This series shows that the ADM can be used both safely and effectively in revisionary cases, resulting in decreased rates of capsular contracture and implant cushioning/stabilization.
SN  - 1090-820X
AD  - Department of Plastic Surgery, Loma Linda University Medical Center, Loma Linda, CA 92354, USA
U2  - PMID: 19944993.
DO  - 10.1016/j.asj.2009.09.007
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104407831
T1  - The use of porcine acellular dermal matrix in silicone implant-based breast reconstruction.
AU  - Himsl I
AU  - Drinovac V
AU  - Lenhard M
AU  - Stöckl D
AU  - Weissenbacher T
AU  - Dian D
Y1  - 2012/07//
N1  - Accession Number: 104407831. Language: English. Entry Date: 20130111. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Continental Europe; Europe. Special Interest: Obstetric Care. NLM UID: 8710213. 
KW  - Breast Implants -- Adverse Effects
KW  - Breast Reconstruction -- Methods
KW  - Patient Satisfaction
KW  - Skin, Artificial
KW  - Adult
KW  - Aged
KW  - Animals
KW  - Biocompatible Materials
KW  - Breast Neoplasms -- Surgery
KW  - Esthetics
KW  - Female
KW  - Human
KW  - Breast Reconstruction -- Adverse Effects
KW  - Mastectomy
KW  - Middle Age
KW  - Silicones
KW  - Swine
KW  - Culture Media
KW  - Touch
SP  - 187
EP  - 192
JO  - Archives of Gynecology & Obstetrics
JF  - Archives of Gynecology & Obstetrics
JA  - ARCH GYNECOL OBSTET
VL  - 286
IS  - 1
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
SN  - 0932-0067
AD  - Department of Obstetrics and Gynaecology, Ludwig-Maximillians-University Hospital, Munich, Germany, Isabelle.himsl@med.uni-muenchen.de.
U2  - PMID: 22382372.
DO  - 10.1007/s00404-012-2266-x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104284694
T1  - Chest wall reconstruction with acellular dermal matrix (Strattice™) and a TRAM flap.
AU  - Brunbjerg, Mette Eline
AU  - Juhl, Alexander Andersen
AU  - Damsgaard, Tine Engberg
Y1  - 2013/06//
N1  - Accession Number: 104284694. Language: English. Entry Date: 20130516. Revision Date: 20150711. Publication Type: Journal Article; case study; pictorial. Journal Subset: Biomedical; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Special Interest: Oncologic Care. NLM UID: 8709065. 
KW  - Breast Neoplasms -- Diagnosis
KW  - Neoplasm Recurrence, Local -- Surgery
KW  - Mastectomy -- Methods
KW  - Breast Reconstruction -- Methods
KW  - Surgical Mesh -- Utilization
KW  - Female
KW  - Aged
SP  - 1052
EP  - 1054
JO  - Acta Oncologica
JF  - Acta Oncologica
JA  - ACTA ONCOL
VL  - 52
IS  - 5
CY  - Philadelphia, Pennsylvania
PB  - Taylor & Francis Ltd
SN  - 0284-186X
AD  - Aarhus University Hospital, Department of Plastic Surgery, Aarhus C., Denmark
DO  - 10.3109/0284186X.2012.734925
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - GEN
ID  - 112398473
T1  - Erratum to: The Multi Centre Canadian Acellular Dermal Matrix Trial (MCCAT): study protocol for a randomized controlled trial in implant-based breast reconstruction.
AU  - Zhong, Toni
AU  - Temple-Oberle, Claire
AU  - Hofer, Stefan O P
AU  - Beber, Brett
AU  - Semple, John
AU  - Brown, Mitchell
AU  - Macadam, Sheina
AU  - Lennox, Peter
AU  - Panzarella, Tony
AU  - McCarthy, Colleen
AU  - Baxter, Nancy
Y1  - 2016/01/20/
N1  - Accession Number: 112398473. Corporate Author: MCCAT Study Group. Language: English. Entry Date: In Process. Revision Date: 20160507. Publication Type: corrected article. Journal Subset: Biomedical; Europe; UK & Ireland. NLM UID: 101263253. 
SP  - 1
EP  - 1
JO  - Trials
JF  - Trials
JA  - TRIALS
VL  - 17
PB  - BioMed Central
AB  - A correction to the article "The Multi Centre Canadian Acellular Dermal Matrix Trial (MCCAT): study protocol for a randomized controlled trial in implant-based breast reconstruction" that was published in the previous issue is presented.
SN  - 1745-6215
AD  - Division of Plastic and Reconstructive Surgery, University Health Network, Toronto, ON, Canada
AD  - Plastic Surgery Oncology, Tom Baker Cancer Centre, Alberta Health Services, Calgary, AB, Canada
AD  - Division of Plastic and Reconstructive Surgery, Vancouver General Hospital and University of British Columbia, Vancouver, BC, Canada
AD  - Division of Biostatistics, University Health Network, Toronto, ON, Canada
AD  - Plastic and Reconstructive Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
AD  - Department of Surgery, St Michael's Hospital, Toronto, and Keenan Research Centre, Toronto, ON, Canada
U2  - PMID: 26790621.
DO  - 10.1186/s13063-016-1179-6
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=112398473&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104576033
T1  - Revisionary breast surgery with acellular dermal matrices.
AU  - Maxwell GP
AU  - Gabriel A
AU  - Maxwell, G Patrick
AU  - Gabriel, Allen
Y1  - 2011/08//
N1  - Accession Number: 104576033. Language: English. Entry Date: 20120323. Revision Date: 20161117. Publication Type: journal article. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
KW  - Breast Implants -- Methods
KW  - Breast Implants
KW  - Foreign-Body Reaction -- Therapy
KW  - Female
SP  - 700
EP  - 710
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 31
IS  - 6
PB  - Oxford University Press / USA
AB  - Revisionary breast surgeries are challenging, and advanced techniques must often be utilized in the correction of the underlying anatomical deformities. In this Featured Operative Technique, the authors describe their method, which includes a combination of revisionary surgery techniques with site change and acellular dermal matrices. This use of acellular dermal matrices has four indications based on the underlying clinical presentation: (1) as a lower pole implant interface (usually for revision mastopexy), (2) as a capsular contracture treatment (technically similar to lower pole interface), (3) as a tissue thickener (superomedial or inferolateral implant interface), or (4) as an implant stabilizer (malposition correction).
SN  - 1090-820X
AD  - Department of Plastic Surgery, Loma Linda University Medical Center, California, USA
AD  - Department of Plastic Surgery, Loma Linda University Medical Center, Loma Linda, California.
U2  - PMID: 21813885.
DO  - 10.1177/1090820X11415395
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104576033&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105192632
T1  - Acellular dermis-assisted breast reconstruction with the use of crescentric tissue expansion: a functional cosmetic analysis of 40 consecutive patients.
AU  - Buck DW 2nd
AU  - Heyer K
AU  - Dibardino D
AU  - Bethke K
AU  - Kim JY
AU  - Buck, Donald W 2nd
AU  - Heyer, Kamaldeep
AU  - DiBardino, David
AU  - Bethke, Kevin
AU  - Kim, John Y S
Y1  - 2010/03//
N1  - Accession Number: 105192632. Language: English. Entry Date: 20100827. Revision Date: 20161117. Publication Type: journal article; research. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
KW  - Breast Implants
KW  - Breast Reconstruction -- Methods
KW  - Tissue Expansion -- Methods
KW  - Adult
KW  - Aged
KW  - Aged, 80 and Over
KW  - Esthetics
KW  - Female
KW  - Human
KW  - Middle Age
KW  - Postoperative Complications
KW  - Questionnaires
KW  - Retrospective Design
KW  - Treatment Outcomes
SP  - 194
EP  - 200
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 30
IS  - 2
PB  - Oxford University Press / USA
AB  - Background: Crescentric tissue expanders have the potential to improve postoperative aesthetic results via selective lower pole expansion; however, limited data are available on their efficacy.Objectives: The authors assess postoperative functional and cosmetic outcomes of acellular dermis-assisted breast reconstruction with crescentric tissue expansion.Methods: This study is a single-institution, retrospective review of 40 consecutive patients who underwent acellular dermis-assisted breast reconstruction with crescentric tissue expansion. Demographic data, operative details, and procedural outcomes were recorded and assessed. Cosmetic outcomes were assessed using the Breast Evaluation Questionnaire.Results: Fifty-eight breasts representing 36 bilateral and 22 unilateral reconstructions were analyzed. Of these, 45 (78%) underwent tissue expander (TE) to implant exchange. The mean interval between stage 1 and stage 2 was 92 +/- 20 days, with a total follow-up time of 141 +/- 16 days. The average intraoperative expander fill volume was 213.5 mL, with an average final fill of 285 mL (range, 180-740 mL). The average number of expansions was 1.6. Overall, there were five complications (8.6%). Eighty-three percent of patients participated in the breast evaluation questionnaire. Answers to each question were reported using a qualitative five-point scale that ranged from 1 (very dissatisfied) to 5 (very satisfied). For the bilateral reconstructions, the average score in all contexts was 4.5 +/- 0.3, 4.33 +/- 0.5, and 4.36 +/- 0.33 for size, shape, and firmness, respectively. For unilateral reconstructions, the average scores were 4.0 +/- 0.58, 3.93 +/- 0.38, and 4.13 +/- 0.21, respectively.Conclusions: Crescentric expander-based reconstruction with acellular dermis assistance is well tolerated, especially in smaller breasted women. Functional and cosmetic outcomes were acceptable and comparable to previous reports of traditional expander-based reconstructions.
SN  - 1090-820X
AD  - Division of Plastic and Reconstructive Surgery, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
AD  - Division of Plastic and Reconstructive Surgery, Northwestern University, Feinberg School of Medicine, Chicago, Illinois.
U2  - PMID: 20442096.
DO  - 10.1177/1090820X10366547
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103996301
T1  - The Multi Centre Canadian Acellular Dermal Matrix Trial (MCCAT): study protocol for a randomized controlled trial in implant-based breast reconstruction.
AU  - Zhong, Toni
AU  - Temple-Oberle, Claire
AU  - Hofer, Stefan
AU  - Beber, Brett
AU  - Semple, John
AU  - Brown, Mitchell
AU  - Macadam, Sheina
AU  - Lennox, Peter
AU  - Panzarella, Tony
AU  - McCarthy, Colleen
AU  - Baxter, Nancy
AU  - Hofer, Stefan O P
Y1  - 2013/01//
N1  - Accession Number: 103996301. Corporate Author: MCCAT Study Group. Language: English. Entry Date: 20141024. Revision Date: 20161222. Publication Type: journal article; research; randomized controlled trial. Journal Subset: Biomedical; Europe; UK & Ireland. NLM UID: 101263253. 
KW  - Dermis
KW  - Breast Implants -- Equipment and Supplies
KW  - Breast Implants -- Economics
KW  - Breast Neoplasms -- Surgery
KW  - Mastectomy
KW  - Study Design
KW  - Breast Implants -- Adverse Effects
KW  - Breast Neoplasms -- Economics
KW  - Breast Neoplasms -- Pathology
KW  - Canada
KW  - Protocols
KW  - Cost Benefit Analysis
KW  - Female
KW  - Health Care Costs
KW  - Human
KW  - Neoplasm Staging
KW  - Patient Satisfaction
KW  - Prosthesis Design
KW  - Quality of Life
KW  - Quality-Adjusted Life Years
KW  - Questionnaires
KW  - Time Factors
KW  - Treatment Outcomes
SP  - 356
EP  - 356
JO  - Trials
JF  - Trials
JA  - TRIALS
VL  - 14
IS  - 1
PB  - BioMed Central
AB  - Background: The two-stage tissue expander/implant (TE/I) reconstruction is currently the gold standard method of implant-based immediate breast reconstruction in North America. Recently, however, there have been numerous case series describing the use of one-stage direct to implant reconstruction with the aid of acellular dermal matrix (ADM). In order to rigorously investigate the novel application of ADM in one-stage implant reconstruction, we are currently conducting a multicentre randomized controlled trial (RCT) designed to evaluate the impact on patient satisfaction and quality of life (QOL) compared to the two-stage TE/I technique.Methods/designs: The MCCAT study is a multicenter Canadian ADM trial designed as a two-arm parallel superiority trial that will compare ADM-facilitated one-stage implant reconstruction compared to two-stage TE/I reconstruction following skin-sparing mastectomy (SSM) or nipple-sparing mastectomy (NSM) at 2 weeks, 6 months, and 12 months. The source population will be members of the mastectomy cohort with stage T0 to TII disease, proficient in English, over the age of 18 years, and planning to undergo SSM or NSM with immediate implant breast reconstruction. Stratified randomization will maintain a balanced distribution of important prognostic factors (study site and unilateral versus bilateral procedures). The primary outcome is patient satisfaction and QOL as measured by the validated and procedure-specific BREAST-Q. Secondary outcomes include short- and long-term complications, long-term aesthetic outcomes using five standardized photographs graded by three independent blinded observers, and a cost effectiveness analysis.Discussion: There is tremendous interest in using ADM in implant breast reconstruction, particularly in the setting of one-stage direct to implant reconstruction where it was previously not possible without the intermediary use of a temporary tissue expander (TE). This unique advantage has led many patients and surgeons alike to believe that one-stage ADM-assisted implant reconstruction should be the procedure of choice and should be offered to patients as the first-line treatment. We argue that it is crucial that this technique be scientifically evaluated in terms of patient selection, surgical technique, complications, aesthetic outcomes, cost-effectiveness, and most importantly patient-reported outcomes before it is promoted as the new gold standard in implant-based breast reconstruction.Trial Registration: ClinicalTrials.gov: NCT00956384.
SN  - 1745-6215
AD  - Division of Plastic & Reconstructive Surgery, University Health Network, Toronto, ON, Canada. toni.zhong@uhn.ca.
U2  - PMID: 24165392.
DO  - 10.1186/1745-6215-14-356
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103996301&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104952780
T1  - A preliminary report on the clinical experience with AlloDerm in breast reconstruction and its radiologic appearance.
AU  - Tran Cao HS
AU  - Tokin C
AU  - Konop J
AU  - Ojeda-Fournier H
AU  - Chao J
AU  - Blair SL
Y1  - 2010/10//
N1  - Accession Number: 104952780. Language: English. Entry Date: 20110121. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; USA. Special Interest: Perioperative Care. NLM UID: 0370522. 
KW  - Breast Neoplasms -- Surgery
KW  - Collagen -- Therapeutic Use
KW  - Breast Reconstruction -- Methods
KW  - Mammography
KW  - Skin, Artificial
KW  - Adult
KW  - Aged
KW  - Breast Neoplasms -- Drug Therapy
KW  - Chemotherapy, Adjuvant
KW  - Female
KW  - Human
KW  - Magnetic Resonance Imaging
KW  - Lumpectomy
KW  - Middle Age
KW  - Retrospective Design
SP  - 1123
EP  - 1126
JO  - American Surgeon
JF  - American Surgeon
JA  - AM SURG
VL  - 76
IS  - 10
CY  - Westwood, Kansas
PB  - Southeastern Surgical Congress
SN  - 0003-1348
AD  - University of California, San Diego Medical Center, San Diego, California 92093-0987, USA.
U2  - PMID: 21105625.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104952780&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105459207
T1  - Pocket conversion made easy: a simple technique using alloderm to convert subglandular breast implants to the dual-plane position.
AU  - Mofid MM
AU  - Singh NK
AU  - Mofid, M Mark
AU  - Singh, Navin K
Y1  - 2009/01//
N1  - Accession Number: 105459207. Language: English. Entry Date: 20090424. Revision Date: 20161117. Publication Type: journal article; research. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
KW  - Biocompatible Materials -- Therapeutic Use
KW  - Breast Implants
KW  - Breast Reconstruction -- Methods
KW  - Collagen -- Therapeutic Use
KW  - Pectoralis Muscles -- Surgery
KW  - Adult
KW  - Case Control Studies
KW  - Female
KW  - Middle Age
KW  - Postoperative Complications -- Prevention and Control
KW  - Reoperation
KW  - Treatment Outcomes
KW  - Human
SP  - 12
EP  - 18
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 29
IS  - 1
PB  - Oxford University Press / USA
AB  - Background: The advantages of dual-plane, partially submuscular breast implants are well documented. Standard conversion techniques to dual-plane positioning use marionette sutures and internal capsulorrhaphy sutures from the lower edge of the pectoralis major muscle to the anterior capsule or breast fascia within the subglandular plane. These techniques are limited by high rates of postoperative implant malposition and technical limitations that make combined mastopexy procedures difficult to perform.Objective: We describe a simple technique familiar to most plastic surgeons accustomed to placing tissue expanders for use in breast reconstruction using Alloderm (LifeCell Corp., Branchburg, NJ) as a sling beneath the pectoralis major muscle to the chest wall.Methods: We studied 25 women who underwent breast augmentation revision from the subglandular to the dual-plane position by performing a 9-year retrospective review from 1999 to 2007 of 2 surgeons' experience. We identified 10 women for whom Alloderm, sutured from the lower edge of the pectoralis major muscle to the chest wall, was used to create a composite pectoralis-Alloderm pocket for partial submuscular transfer of implants and 15 case controls who underwent pocket conversion using standard capsulorrhaphy and marionette suture techniques.Results: The principal outcome variable of at least 1 complication was 73.3% without Alloderm, resulting in a 40% need for revision surgery, versus 0% with Alloderm (Fisher exact test; P < .05).Conclusions: The standard techniques available for conversion of subglandular breast implants to the dual-plane position using capsulorrhaphy and marionette sutures are limited by a high complication rate for the reliable positioning into a stable dual-plane pocket during implant exchange. A commonly used technique in reconstructive breast surgery using Alloderm is shown to reliably convert subglandular implants to the dual-plane position.
SN  - 1090-820X
AD  - Department of Surgery, Division of Plastic Surgery, University of California-San Diego School of Medicine, San Diego, CA, USA
AD  - Department of Surgery, Division of Plastic Surgery, University of California-San Diego School of Medicine, San Diego, CA, USA. drmofid@mofidplasticsurgery.com
U2  - PMID: 19233000.
DO  - 10.1016/j.asj.2008.12.005
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109754132
T1  - Acellular bovine pericardium dermal matrix in immediate breast reconstruction after Skin Sparing Mastectomy.
AU  - Gubitosi, A
AU  - Docimo, G
AU  - Parmeggiani, D
AU  - Pirozzi, R
AU  - Vitiello, C
AU  - Schettino, P
AU  - Avellino, M
AU  - Casalino, G
AU  - Amato, M
AU  - Ruggiero, R
AU  - Docimo, L
Y1  - 2014/08/02/Aug2014 Supplement 1
N1  - Accession Number: 109754132. Language: English. Entry Date: 20150814. Revision Date: 20150923. Publication Type: Journal Article; research. Supplement Title: Aug2014 Supplement 1. Journal Subset: Biomedical; USA. Special Interest: Perioperative Care. NLM UID: 101228232. 
KW  - Dermis
KW  - Breast Reconstruction -- Methods
KW  - Pericardium -- Transplantation
KW  - Skin Transplantation -- Methods
KW  - Adult
KW  - Aged
KW  - Animals
KW  - Breast Neoplasms -- Surgery
KW  - Cattle
KW  - Female
KW  - Prospective Studies
KW  - Human
KW  - Middle Age
KW  - Retrospective Design
SP  - S205
EP  - 8
JO  - International Journal of Surgery
JF  - International Journal of Surgery
JA  - INT J SURG
VL  - 12
CY  - New York, New York
PB  - Elsevier B.V.
SN  - 1743-9191
AD  - Department of Surgery, Second University of Naples, Via Pansini 5, 80131 Naples, Italy.
AD  - Department of Clinical Medicine and Surgery, University of Naples Federico II, Italy.
AD  - Department of Surgery, Second University of Naples, Via Pansini 5, 80131 Naples, Italy. Electronic address: roberto.ruggiero@unina2.it.
U2  - PMID: 24859403.
DO  - 10.1016/j.ijsu.2014.05.007
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109754132&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104583492
T1  - Acellular dermal matrix in aesthetic revisionary breast surgery.
AU  - Maxwell GP
AU  - Gabriel A
AU  - Maxwell, G Patrick
AU  - Gabriel, Allen
Y1  - 2011/09/02/2011 Supplement 1
N1  - Accession Number: 104583492. Language: English. Entry Date: 20120323. Revision Date: 20161117. Publication Type: journal article. Supplement Title: 2011 Supplement 1. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
KW  - Breast Implants -- Methods
KW  - Breast Implants -- Adverse Effects
KW  - Collagen -- Therapeutic Use
KW  - Biocompatible Materials -- Therapeutic Use
KW  - Female
KW  - Foreign-Body Reaction -- Surgery
KW  - Postoperative Complications
KW  - Reoperation -- Methods
SP  - 65S
EP  - 76S
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 31
PB  - Oxford University Press / USA
AB  - Breast augmentation is one of the most commonly-performed cosmetic procedures worldwide. Unfortunately, many women require revisionary surgery related to unsatisfactory results or complications such as capsular contracture, implant malposition, and ptosis. While, historically, surgeons have relied on often-imperfect native tissue to correct these deformities, acellular dermal matrix (ADM) offers a new option for solving these difficult aesthetic problems. In this article, the authors provide background information about the role of ADM in providing excellent and lasting results to cosmetic breast augmentation patients, and they describe their method of subpectoral revisionary augmentation with ADM.
SN  - 1090-820X
AD  - Department of Plastic Surgery, Loma Linda University Medical Center, Loma Linda, California, USA
AD  - Department of Plastic Surgery, Loma Linda University Medical Center, Loma Linda, California.
U2  - PMID: 21908825.
DO  - 10.1177/1090820X11418333
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104583492&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108229847
T1  - Chest wall reconstruction with porcine acellular dermal matrix (strattice) and a latissimus myocutaneous flap.
AU  - Huston TL
AU  - Taback B
AU  - Rohde CH
Y1  - 2011/06//
N1  - Accession Number: 108229847. Language: English. Entry Date: 20110916. Revision Date: 20150712. Publication Type: Journal Article; case study. Journal Subset: Biomedical; USA. Special Interest: Perioperative Care. NLM UID: 0370522. 
KW  - Breast Neoplasms -- Pathology
KW  - Surgery, Reconstructive -- Methods
KW  - Ribs -- Pathology
KW  - Ribs -- Surgery
KW  - Skin, Artificial
KW  - Thoracic Surgery
KW  - Breast Neoplasms -- Surgery
KW  - Female
KW  - Mastectomy
KW  - Middle Age
SP  - 115
EP  - 116
JO  - American Surgeon
JF  - American Surgeon
JA  - AM SURG
VL  - 77
IS  - 6
CY  - Westwood, Kansas
PB  - Southeastern Surgical Congress
SN  - 0003-1348
U2  - PMID: 21679622.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108229847&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104583490
T1  - Acellular dermal matrix inlays to correct significant implant malposition in patients with compromised local tissues.
AU  - Shestak KC
AU  - Shestak, Kenneth C
Y1  - 2011/09/02/2011 Supplement 1
N1  - Accession Number: 104583490. Language: English. Entry Date: 20120323. Revision Date: 20161117. Publication Type: journal article; case study; research. Supplement Title: 2011 Supplement 1. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
KW  - Breast Implants -- Methods
KW  - Breast Implants -- Adverse Effects
KW  - Collagen -- Therapeutic Use
KW  - Adult
KW  - Female
KW  - Middle Age
KW  - Reoperation
KW  - Retrospective Design
SP  - 85S
EP  - 94S
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 31
PB  - Oxford University Press / USA
AB  - Breast implant malposition is an increasingly recognized complication of breast augmentation and implant-based breast reconstruction. Etiologic factors include technical imprecision during surgery with overdissection or inadequate dissection of the pocket, inappropriately large implant selection, and the compromise of the local breast tissues, which produces an inability of a patient's natural tissues to support an implant in the placed position. In this article, the author describes a series of 19 patients with significant breast implant malposition following staged implant breast reconstruction in the setting of locally compromised tissues. Given the results, the author believes that an effective technique in the correction of severe implant malposition is reconfiguration and reconstruction of the periprosthetic capsular space, with a combination of focal "mirror image" capsule excision and permanent suture repair to restore breast folds, along with an acellular dermal matrix inlay technique designed to confer structural support to this repair. This strategy merits consideration in patients who have significant implant malposition in the face of severely compromised local breast tissues.
SN  - 1090-820X
AD  - Plastic Surgery Service at Magee-Womens Hospital, Division of Plastic Surgery, Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 5213, USA
AD  - Plastic Surgery Service at Magee-Womens Hospital in the Division of Plastic Surgery, Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
U2  - PMID: 21908827.
DO  - 10.1177/1090820X11418337
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104583490&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107306983
T1  - Wound fluids and the pathogenesis of chronic wounds.
AU  - Wysocki AB
Y1  - 1996/11//1996 Nov
N1  - Accession Number: 107306983. Language: English. Entry Date: 19970101. Revision Date: 20150819. Publication Type: Journal Article; research; tables/charts. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Grant Information: Supported by NIH grants NR03212, NR03898, and NR03809. Supported also by NIH grants NR06263 (to Dr. Wysocki), GM31321 and GM21681 (to Dr. Grinnell), and GM26145 and GM42461 (to Dr. Staiano-Coico). NLM UID: 9435679. 
KW  - Exudates and Transudates -- Analysis
KW  - Wound Healing -- Physiology
KW  - Fibronectins -- Physiology
KW  - Wounds and Injuries -- Physiopathology
KW  - Enzymes -- Physiology
KW  - Adult
KW  - Middle Age
KW  - Aged
KW  - Female
KW  - Male
KW  - Specimen Handling
KW  - Technology, Medical
KW  - Electrophoresis
KW  - Blister
KW  - Leg Ulcer
KW  - Funding Source
KW  - Human
SP  - 283
EP  - 290
JO  - Journal of Wound, Ostomy & Continence Nursing
JF  - Journal of Wound, Ostomy & Continence Nursing
JA  - J WOCN
VL  - 23
IS  - 6
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - Purpose: To describe two areas of ongoing investigation into analysis of wound fluids that may eventually lead to better understanding of pathophysiology of chronic wounds and to improved care and treatment. Methods: Studies used Lowry protein assay, sodium dodecyl sulfate polyacrylamide gel electrophoresis, Western blotting, and zymography to analyze fluids from acute and chronic wounds and serum samples collected from healthy and affected volunteers. Subjects: Thirty-one subjects with ages ranging from 32 to 79 years participated in the research; fluid was collected from chronic wounds in 10 patients (two female, four male, and four unrecorded), fluid was collected from acute mastectomy wounds in 15 patients (all female), blister fluid and blood were collected from two volunteers (one male, one female), and blood for serum preparation was collected from four volunteers (two female, two male). Primary outcome variables: (1) Fibronectin degradation and (2) expression of matrix metalloproteinases. Results: Fibronectin can be degraded in fluid from chronic wounds but remains intact in blood-derived serum, plasma-derived serum, blister fluid, and mastectomy wound fluid. Matrix metalloproteinases are overexpressed in fluid from chronic wounds compared with mastectomy wound fluid, blood-derived serum, and plasma-derived serum. Matrix metalloproteinases are also expressed at somewhat higher levels in mastectomy fluid than in blood-derived and plasma-derived serum. Conclusions: These studies identified two factors that may contribute to delayed healing of chronic wound fibronectin degradation and overexpression of matrix metalloproteinases.
SN  - 1071-5754
AD  - Department of Nursing, Ronald O. Perelman Department of Dermatology, New York University Medical Center, 550 First Ave., PHL-875, New York, NY 10016
U2  - PMID: 9043277.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107306983&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107842964
T1  - Evolving role of alloderm in breast surgery.
AU  - Gabriel, Allen
AU  - Maxwell, G. Patrick
Y1  - 2011/10//Oct-Dec2011
N1  - Accession Number: 107842964. Language: English. Entry Date: 20140425. Revision Date: 20150712. Publication Type: Journal Article; pictorial; review. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 8403490. 
KW  - Breast Reconstruction -- Methods
KW  - Patient Safety
KW  - Skin Transplantation -- History
KW  - Transplant Donors
KW  - Breast
KW  - Breast Reconstruction -- History
KW  - Nipples
KW  - Postoperative Complications
KW  - Radiotherapy
KW  - Skin Transplantation -- Methods
SP  - 141
EP  - 150
JO  - Plastic Surgical Nursing
JF  - Plastic Surgical Nursing
JA  - PLAST SURG NURS
VL  - 31
IS  - 4
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
SN  - 0741-5206
AD  - Department of Plastic Surgery, Loma Linda University Medical Center, Loma Linda, CA
U2  - PMID: 22157603.
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 104583495
T1  - Acellular dermal matrix in primary breast reconstruction.
AU  - Sbitany H
AU  - Langstein HN
AU  - Sbitany, Hani
AU  - Langstein, Howard N
Y1  - 2011/09/02/2011 Supplement 1
N1  - Accession Number: 104583495. Language: English. Entry Date: 20120323. Revision Date: 20161117. Publication Type: journal article; review. Supplement Title: 2011 Supplement 1. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
KW  - Biocompatible Materials -- Therapeutic Use
KW  - Breast Implants -- Methods
KW  - Breast Reconstruction -- Methods
KW  - Animals
KW  - Breast Implants
KW  - Collagen -- Therapeutic Use
KW  - Female
SP  - 30S
EP  - 7S
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 31
PB  - Oxford University Press / USA
AB  - The use of acellular dermal matrix (ADM) in many plastic surgery procedures, including breast reconstruction, has increased dramatically in recent years. While expander/implant reconstruction can be performed successfully with standard techniques, the introduction of ADM has added a new tool with which to achieve lasting, predictable results. This article is a summary of existing literature on ADM for primary implant reconstruction, to provide a more thorough understanding of the benefits of ADM in single- and to two-stage breast reconstruction and to identify the areas where further investigation is needed.
SN  - 1090-820X
AD  - Division of Plastic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
AD  - Dr. Sbitany is a Reconstructive Microsurgery Fellow in the Division of Plastic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.
U2  - PMID: 21908822.
DO  - 10.1177/1090820X11417577
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ER  - 

TY  - JOUR
ID  - 104583494
T1  - Acellular dermal matrix for secondary procedures following prosthetic breast reconstruction.
AU  - Nahabedian MY
AU  - Spear SL
AU  - Nahabedian, Maurice Y
AU  - Spear, Scott L
Y1  - 2011/09/02/2011 Supplement 1
N1  - Accession Number: 104583494. Language: English. Entry Date: 20120323. Revision Date: 20161117. Publication Type: journal article; review. Supplement Title: 2011 Supplement 1. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
KW  - Breast Implants -- Methods
KW  - Breast Reconstruction -- Methods
KW  - Nipples -- Surgery
KW  - Biocompatible Materials -- Therapeutic Use
KW  - Breast Implants -- Adverse Effects
KW  - Collagen -- Therapeutic Use
KW  - Female
KW  - Patient Selection
SP  - 38S
EP  - 50S
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 31
PB  - Oxford University Press / USA
AB  - Acellular dermal matrices (ADM) have generated interest for their possible applications in secondary revisions following prosthetic breast reconstruction. These materials can be effective in a variety of situations, including implant displacement, synmastia, capsular contracture, incisional support, and pocket conversion. ADM can also be placed in the setting of delayed breast reconstruction and to augment nipple projection. These biomaterials have demonstrated feasibility and success for many complex deformities. However, there is an associated learning curve that includes an understanding of proper technique and patient selection. The authors review their cumulative experience between 2004 and 2010 with ADM for the correction of secondary deformities following prosthetic breast reconstruction, focusing on the indications for repair, traditional management, and management with ADM.
SN  - 1090-820X
AD  - Department of Plastic Surgery, Georgetown University Hospital, Washington, DC 20007, USA
AD  - Department of Plastic Surgery, Georgetown University Hospital, Washington, DC.
U2  - PMID: 21908823.
DO  - 10.1177/1090820X11418093
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ER  - 

TY  - JOUR
ID  - 104583493
T1  - Acellular dermal matrix in breast reconstruction in the setting of radiotherapy.
AU  - Israeli R
AU  - Feingold RS
AU  - Israeli, Ron
AU  - Feingold, Randall S
Y1  - 2011/09/02/2011 Supplement 1
N1  - Accession Number: 104583493. Language: English. Entry Date: 20120323. Revision Date: 20161117. Publication Type: journal article; review. Supplement Title: 2011 Supplement 1. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
KW  - Breast Implants -- Methods
KW  - Breast Neoplasms -- Surgery
KW  - Collagen -- Therapeutic Use
KW  - Animals
KW  - Biocompatible Materials -- Therapeutic Use
KW  - Breast Implants
KW  - Breast Neoplasms -- Radiotherapy
KW  - Female
KW  - Breast Reconstruction -- Methods
KW  - Radiotherapy, Adjuvant -- Methods
SP  - 51S
EP  - 64S
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 31
PB  - Oxford University Press / USA
AB  - Acellular dermal matrices (ADM) are becoming an integral component of immediate implant-based breast reconstruction, providing inferolateral coverage and support of the implant. Currently, five ADM products are available on the market for this purpose. Although their application has resulted in improved aesthetic results with low complication rates, the clinical performance of ADM when radiotherapy is a component of breast cancer treatment has yet to be defined. In this article, we present a thorough review of the current literature on the performance of ADM in the setting of radiotherapy from both animal and human studies, including our own experience with two proprietary ADM products. The other three products have little literature documenting their application for this type of reconstruction, and further studies specifically evaluating the performance of all ADM formulations in the setting of radiotherapy are still needed.
SN  - 1090-820X
AD  - Division of Plastic Surgery, Department of Surgery, Hofstra University School of Medicine, in partnership with North Shore-LIJ Health System, Hempstead, New York, USA
AD  - Division of Plastic Surgery, Department of Surgery, Hofstra University School of Medicine, in partnership with North Shore-LIJ Health System, Hempstead, New York.
U2  - PMID: 21908824.
DO  - 10.1177/1090820X11418089
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ER  - 

TY  - JOUR
ID  - 104583491
T1  - Acellular dermal matrix in cosmetic breast procedures and capsular contracture.
AU  - Mofid MM
AU  - Mofid, M Mark
Y1  - 2011/09/02/2011 Supplement 1
N1  - Accession Number: 104583491. Language: English. Entry Date: 20120323. Revision Date: 20161117. Publication Type: journal article; review. Supplement Title: 2011 Supplement 1. Journal Subset: Biomedical; Mexico & Central/South America; Peer Reviewed. Special Interest: Perioperative Care. NLM UID: 9707469. 
KW  - Breast Implants -- Methods
KW  - Collagen -- Therapeutic Use
KW  - Foreign-Body Reaction -- Surgery
KW  - Animals
KW  - Biocompatible Materials -- Therapeutic Use
KW  - Breast Implants -- Adverse Effects
KW  - Female
KW  - Foreign-Body Reaction -- Pathology
SP  - 77S
EP  - 84S
JO  - Aesthetic Surgery Journal
JF  - Aesthetic Surgery Journal
JA  - AESTHETIC SURG J
VL  - 31
PB  - Oxford University Press / USA
AB  - Prevention and treatment of capsular contracture after breast augmentation is a controversial and oftentimes vexing problem. While there are traditional methods of addressing this condition, acellular dermal matrix materials offer a new and promising modality that is gaining momentum in the field of plastic surgery. In this article, the author examines the etiology and pathophysiology of capsular contracture and review the existing literature on acellular dermal matrix in breast surgery related to capsular contracture.
SN  - 1090-820X
AD  - Division of Plastic Surgery, University of California, San Diego, California, USA
AD  - Division of Plastic Surgery, University of California, San Diego, California.
U2  - PMID: 21908826.
DO  - 10.1177/1090820X11418201
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ER  -