TY - JOUR AB - In speaking of the indications for external surgery, we generally find pain as the first symptom. Fever, rapid pulse and difficulty in swallowing rapidly ensue. Swelling of the tissues and emphysema are also accompanying signs. The emphysema may be present in a slight degree and remain unrecognized unless the X-ray is employed, as explained by Iglauer in 1924. The X-ray is an important adjunct for determining the amount of swelling and the progress of the case. With these signs present, and, in addition, a high white count, there is every reason for opening the neck. Of course, each case is a problem in itself, and no set rules should guide the surgeon in handling it. Marscke remarks that it is safer to operate too often than to withhold operation. From my experience with the last case reported this appeals to me. The infection first establishes itself in the loose perioesophageal tissues, and from there spreads out into the fascial planes of the neck, descending between the sheaths into the mediastinum. It is a relatively simple matter in upper esophageal perforations to open the neck and drain this area. It is not essential to remove the foreign body through the incision but it is essential to provide drainage. If the foreign body is found outside the esophagus, as in the case reported by Iglauer and Ransohoff, it can be removed. I believe that Marschik's method is a very effective one for establishing drainage and preventing the descent of the infection. His technic briefly is to open the neck in front of the sternomastoid muscle, bluntly dissecting clown to the anterior margin of the vascular sheath. The omohyroid muscle is divided and, following the course of the vessels, an iodoform gauze strip is packed in place at their lowermost limit to wall off the anterior mediastinum. The thyroid gland is then lifted forward and an iodoform gauze tampon inserted beneath it to wall off the posterior mediastinum. The abscess cavity is then drained. Marschik refers to this procedure as prophylactic mediastinotomy. © 1929, SAGE Publications. All rights reserved. AD - Cincinnati, United States AU - King, E. DB - Scopus DO - 10.1177/000348942903800205 IS - 2 M3 - Article N1 - Export Date: 10 November 2020 PY - 1929 SP - 351-362 ST - XXIX. Perforation of the esophagus with report of six cases T2 - Annals of Otology, Rhinology & Laryngology TI - XXIX. Perforation of the esophagus with report of six cases UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84964157035&doi=10.1177%2f000348942903800205&partnerID=40&md5=c2ed6c7b38ceced2eb756768930c3737 VL - 38 ID - 1790 ER - TY - JOUR AB - IMPORTANCE: Serious, preventable surgical events, termed never events, continue to occur despite considerable patient safety efforts. OBJECTIVE: To examine the incidence and root causes of and interventions to prevent wrong-site surgery, retained surgical items, and surgical fires in the era after the implementation of the Universal Protocol in 2004. DATA SOURCES: We searched 9 electronic databases for entries from 2004 through June 30, 2014, screened references, and consulted experts. STUDY SELECTION: Two independent reviewers identified relevant publications in June 2014. DATA EXTRACTION AND SYNTHESIS: One reviewer used a standardized form to extract data and a second reviewer checked the data. Strength of evidence was established by the review team. Data extraction was completed in January 2015. MAIN OUTCOMES AND MEASURES: Incidence of wrong-site surgery, retained surgical items, and surgical fires. RESULTS: We found 138 empirical studies that met our inclusion criteria. Incidence estimates for wrong-site surgery in US settings varied by data source and procedure (median estimate, 0.09 events per 10,000 surgical procedures). The median estimate for retained surgical items was 1.32 events per 10,000 procedures, but estimates varied by item and procedure. The per-procedure surgical fire incidence is unknown. A frequently reported root cause was inadequate communication. Methodologic challenges associated with investigating changes in rare events limit the conclusions of 78 intervention evaluations. Limited evidence supported the Universal Protocol (5 studies), education (4 studies), and team training (4 studies) interventions to prevent wrong-site surgery. Limited evidence exists to prevent retained surgical items by using data-matrix-coded sponge-counting systems (5 pertinent studies). Evidence for preventing surgical fires was insufficient, and intervention effects were not estimable. CONCLUSIONS AND RELEVANCE: Current estimates for wrong-site surgery and retained surgical items are 1 event per 100,000 and 1 event per 10,000 procedures, respectively, but the precision is uncertain, and the per-procedure prevalence of surgical fires is not known. Root-cause analyses suggest the need for improved communication. Despite promising approaches and global Universal Protocol evaluations, empirical evidence for interventions is limited. AD - Southern California Evidence-Based Practice Center, RAND Corporation, Santa Monica. Department of Surgery, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California3Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles. Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles. Department of Surgery, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California4Robert Wood Johnson Clinical Scholars Program, University of California, Los Angeles. Evidence-Based Synthesis Program (ESP) Center, West Los Angeles Veterans Affairs Medical Center, Los Angeles, California. RAND Health, RAND Corporation, Santa Monica, California. AN - 26061125 AU - Hempel, S. AU - Maggard-Gibbons, M. AU - Nguyen, D. K. AU - Dawes, A. J. AU - Miake-Lye, I. AU - Beroes, J. M. AU - Booth, M. J. AU - Miles, J. N. AU - Shanman, R. AU - Shekelle, P. G. DA - Aug DO - 10.1001/jamasurg.2015.0301 DP - NLM ET - 2015/06/11 IS - 8 KW - Clinical Protocols Databases, Factual Fires/prevention & control/*statistics & numerical data Foreign Bodies/epidemiology/*prevention & control Humans Incidence Medical Errors/prevention & control/*statistics & numerical data *Patient Safety Root Cause Analysis United States/epidemiology LA - eng N1 - 2168-6262 Hempel, Susanne Maggard-Gibbons, Melinda Nguyen, David K Dawes, Aaron J Miake-Lye, Isomi Beroes, Jessica M Booth, Marika J Miles, Jeremy N V Shanman, Roberta Shekelle, Paul G Journal Article Research Support, U.S. Gov't, Non-P.H.S. Review Systematic Review United States JAMA Surg. 2015 Aug;150(8):796-805. doi: 10.1001/jamasurg.2015.0301. PY - 2015 SN - 2168-6254 SP - 796-805 ST - Wrong-Site Surgery, Retained Surgical Items, and Surgical Fires : A Systematic Review of Surgical Never Events T2 - JAMA Surg TI - Wrong-Site Surgery, Retained Surgical Items, and Surgical Fires : A Systematic Review of Surgical Never Events VL - 150 ID - 163 ER - TY - JOUR AB - The history of a wound and its clinical appearance help the clinician make appropriate decisions on management. The level of contamination in the wound can be determined with the rapid biopsy fixation technique. Extensive wound debridement, high-pressure irrigation, and cautious use of antibiotics should reduce the bacterial count to a level that allows primary healing. The use of sutures of appropriate chemical and physical characteristics should minimize suture contribution to the development of wound infection. Coverage of the wound after closure protects it from external contaminants and allows for completion of epithelialization. Immobilization and, if possible, elevation of the wounded part decrease secondary edema formation. AD - Dep. Surg., Duke Univ. Med. Cent., Durham, NC 27710 AU - Georgiade, G. S. C1 - xylocaine DB - Embase Medline DO - 10.1080/00325481.1983.11697810 IS - 3 KW - polyethylene terephthalate lidocaine polyglycolic acid diagnosis drug therapy foreign body human short survey therapy wound infection wound irrigation xylocaine LA - English M3 - Article N1 - L13162328 1983-05-19 PY - 1983 SN - 0032-5481 SP - 247-254 ST - Wound contamination. Assessment, prevention, and management T2 - Postgraduate Medicine TI - Wound contamination. Assessment, prevention, and management UR - https://www.embase.com/search/results?subaction=viewrecord&id=L13162328&from=export http://dx.doi.org/10.1080/00325481.1983.11697810 VL - 73 ID - 680 ER - TY - JOUR AB - Bezoars are commonly found in the stomach, which are usually trichobezoar or phytobezoar. Signs and symptoms depend on the location and type of bezoars. Small intestinal perforation following wire bezoar has not been reported earlier. We report a 26-year-old schizophrenic male presented to us with features of perforation peritonitis. Preoperative abdominal radiograph was suggestive of unexpected intraoperative findings. Celiotomy with gastrostomy, feeding jejunostomy, and primary closure of perforation over a large bore T-tube was done. The patient was discharged after prolonged hospitalization. Wire bezoar presenting with jejunal perforation has not been reported earlier although every high possibility of perforation exists when the wires are pointed and long, where negotiation at the duodenojejunal flexure may be difficult. © 2019 Journal of Medical Society. AD - Department of Surgery, Down Town Hospital, Dispur, Guwahati, Assam, India Paediatric Surgery Division, Department of Surgery, Down Town Hospital, Dispur, Guwahati, Assam, India AU - Roy, A. K. AU - Lyngdoh, T. S. DB - Scopus DO - 10.4103/jms.jms_39_18 IS - 1 KW - Jejunal perforation Schizophrenia Wire bezoar M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 59-61 ST - Wire bezoar - Unique presentation with duedenojejunal flexure perforation T2 - JMS - Journal of Medical Society TI - Wire bezoar - Unique presentation with duedenojejunal flexure perforation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076959130&doi=10.4103%2fjms.jms_39_18&partnerID=40&md5=fefedaf84fb93fc838d49a8b176c6642 VL - 33 ID - 1041 ER - TY - JOUR AD - Theatre Manager, St. George Private Hospital, Sydney, NSW AN - 106597616. Language: English. Entry Date: 20050325. Revision Date: 20150820. Publication Type: Journal Article. Journal Subset: Australia & New Zealand AU - Berryman, R. DA - 2004 Summer DB - ccm DP - EBSCOhost IS - 4 KW - Foreign Bodies -- Prevention and Control Postoperative Complications Surgical Count Procedure Australia Foreign Bodies -- Diagnosis Foreign Bodies -- Legislation and Jurisprudence Foreign Bodies -- Risk Factors Foreign Bodies -- Surgery Foreign Bodies -- Symptoms Jurisprudence Liability, Legal Malpractice Perioperative Nursing Surgical Sponges United States N1 - Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. PY - 2004 SN - 1448-7535 SP - 20-24 ST - Why count instruments and sponges in the operating room? Stories from home and abroad T2 - ACORN: The Journal of Perioperative Nursing in Australia TI - Why count instruments and sponges in the operating room? Stories from home and abroad UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106597616&site=ehost-live&scope=site VL - 17 ID - 857 ER - TY - JOUR AB - Introduction: Enteral nutrition by percutaneous gastrostomy tube (PEG) is generally safe and effective, but serious complication can occur in 1.5-4 % of cases. Here, we report a case of small bowel obstruction from inadvertent dislodgment and migration of the PEG tube into the terminal ileum, causing small bowel obstruction with successful endoscopic retrieval of the dislodged tube. Case Report: A 96-year-old male with severe dementia presented to the emergency department from a nursing home with abdominal discomfort and distension for 2 days. The patient had PEG tube placed a few years ago at an outside facility to maintain adequate calorie intake. However, the tube was not utilized since the patient was able to handle food by mouth. His nurse at the facility reported that the PEG tube had been missing for few days. At presentation, vital signs were stable. Abdominal examination revealed moderately distended abdomen with generalized tenderness but no guarding or rigidity. Bowel sounds were hyperactive. Lab work showed white blood cell counts of 3.3 thou/mm3 and hemoglobin of 8.9 g/dL, platelets 85 Thou/mm3. Abdominal x-ray showed small bowel obstruction (SBO) with foreign object seen close to the ileocecal valve region possibly a PEG tube bumper. Abdominal CT scan confirmed the partial SBO secondary to PEG tube with its bumper located in the distal ileum. After hydration, nasogastric decompression, patient underwent colono-ileoscopy under general anesthesia. The PEG tube and its bumper were seen about 20 cm proximal to the ileocecal valve and were successfully retrieved with a snare. After the procedure, the patient developed sepsis from the bowel obstruction. He was transferred to the ICU. As his condition continued to decline, support was withdrawn according to the patient and the family wishes. Conclusion: SBO due to internal migration of PEG tube is a potentially unreported complication; retrieving it endoscopically is a feasible option in an appropriate clinical setting. (Figure Presented). AD - Y. Alastal, University of Toledo, Department of Internal Medicine, Division of Gastroenterology, Toledo, OH, United States AU - Alastal, Y. AU - Hammad, T. AU - Bawany, M. AU - Alaradi, O. AU - Nawras, A. DB - Embase DO - 10.1038/ajg.2014.279 KW - hemoglobin American college gastroenterology tube human patient small intestine obstruction ileum ileocecal valve enteric feeding case report nurse stomach tube dementia caloric intake computer assisted tomography thrombocyte food general anesthesia vital sign examination male rigidity intestine sound abdominal discomfort nursing home leukocyte count emergency ward hydration decompression procedures sepsis intestine obstruction abdomen abdominal radiography LA - English M3 - Conference Abstract N1 - L71750045 2015-02-03 PY - 2014 SN - 0002-9270 SP - S336-S337 ST - Where is my peg tube? T2 - American Journal of Gastroenterology TI - Where is my peg tube? UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71750045&from=export http://dx.doi.org/10.1038/ajg.2014.279 VL - 109 ID - 442 ER - TY - JOUR AB - Over the last few decades, paediatric gastroenterology has rapidly developed into a well-established sub-specialty. Improvements in training and equipment have led to enhanced safety with fewer complications following endoscopies. In specialized units, diagnostic and therapeutic upper gastrointestinal endoscopy and proctosigmoidoscopy/colonoscopy are regularly performed under conscious sedation or general anaesthesia. Emerging guidelines and new advances in the diagnostic tools are being incorporated into routine paediatric gastrointestinal endoscopy practice. © 2014 Elsevier Ltd. AD - Queen's Hospital, Burton Upon Trent, United Kingdom AU - Ahmed, M. AU - Karupaiah, A. DB - Scopus DO - 10.1016/j.paed.2014.01.008 IS - 11 KW - Children Colonoscopy Criteria Endoscopy Gastrointestinal tract M3 - Review N1 - Cited By :1 Export Date: 10 November 2020 PY - 2014 SP - 506-512 ST - When to do paediatric gastrointestinal endoscopy? T2 - Paediatrics and Child Health (United Kingdom) TI - When to do paediatric gastrointestinal endoscopy? UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84922553062&doi=10.1016%2fj.paed.2014.01.008&partnerID=40&md5=2f1d28cb8ef7b9bf7871010fcc429f43 VL - 24 ID - 1292 ER - TY - JOUR AD - RNC, Women's and Children's Services, Christiana Care Health Care Services, Newark, DE MSN, RNC, Women's and Children's Services, Christiana Care Health Care Services, Newark, DE. AN - 104663086. Language: English. Entry Date: 20110901. Revision Date: 20150711. Publication Type: Journal Article AU - Townsend, Christine AU - Skinner, Nancy DB - ccm DO - 10.1111/j.1552-6909.2010.01121_47.x DP - EBSCOhost KW - Vaginal Birth Surgical Sponges Surgical Count Procedure Documentation Quality Improvement N1 - abstract. Supplement Title: Sep2010 Supplement 1. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. NLM UID: 8503123. PY - 2010 SN - 0884-2175 SP - S82-S82 ST - When Counts Count: Improving Practice and Documentation T2 - JOGNN: Journal of Obstetric, Gynecologic & Neonatal Nursing TI - When Counts Count: Improving Practice and Documentation UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104663086&site=ehost-live&scope=site VL - 39 ID - 923 ER - TY - JOUR AD - Perioperative Nurse, New Britain (Conn) General Hospital AN - 106921368. Language: English. Entry Date: 20050507. Revision Date: 20200708. Publication Type: Journal Article AU - Denault, D. L. DB - ccm DO - 10.1097/00152193-200204000-00024 DP - EBSCOhost IS - 4 KW - Perioperative Nursing Surgical Count Procedure Patient Advocacy Patient Safety Nurse-Physician Relations N1 - anecdote. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. NLM UID: 7600137. PY - 2002 SN - 0360-4039 SP - 32hn8-32hn8 ST - What counts most in the operating room: standing up to a surgeon is tough, but how else could this nurse protect her patient? T2 - Nursing TI - What counts most in the operating room: standing up to a surgeon is tough, but how else could this nurse protect her patient? UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106921368&site=ehost-live&scope=site VL - 32 ID - 887 ER - TY - JOUR AB - Background: Cross-linked hyaluronan - also called Hylan G-F 20 - is a medical device developed to treat osteoarthritis of the knee. However, it is still controversial whether Hylan G-F 20 has a cartilage protective effect in trauma-induced osteoarthritis. We investigated whether Hylan G-F 20 delayed osteoarthritis progression in a partial meniscectomized rat model. Methods: Lewis rats were used for the experiments. The anterior medial meniscus was resected at the level of the medial collateral ligament in both knees. From 1 week after the surgery, 50 μl of Hylan G-F 20 was injected weekly into the left knee and phosphate buffered saline was injected into the right knee. Cartilage was evaluated for macroscopic findings, histology with safranin-o, and expression of type II collagen at 2, 4, and 8 weeks. Synovitis was also evaluated, and immunohistochemical analysis was performed for ED1. Results: Macroscopic findings demonstrated that India ink positive area, representing fibrillated cartilage, was significantly smaller in the Hylan G-F 20 group than in the control group at 2, 4, and 8 weeks (n = 5). There were no significant differences in osteophyte score between the Hylan G-F 20 group and the control group at 2, 4, and 8 weeks. Histologically, the cartilage in the medial tibial plateau was destroyed at 8 weeks in the control group, while type II collagen expression was still observed at 8 weeks in the Hylan G-F 20 group. OARSI score for cartilage histology was significantly lower in the Hylan G-F 20 group than in the control group at 4 and 8 weeks (n = 5). There were no significant differences in synovial cell number or modified synovitis score between the Hylan G-F 20 group and the control group at 2, 4, and 8 weeks (n = 5). In the Hylan G-F 20 group, foreign bodies surrounded by ED1 positive macrophages were observed in the synovium. Conclusion: Weekly injections of Hylan G-F 20 starting 1 week after surgery delayed cartilage degeneration after meniscectomy in a rat model. Synovitis induced by meniscectomy was not alleviated by Hylan G-F 20. Insoluble gels were observed in the synovium after the Hylan G-F 20 injection. © 2016 Yanagisawa et al. AD - Department of Joint Surgery and Sports Medicine, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, 113-8510, Japan Center for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan Department of Cartilage Regeneration, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, 113-8510, Japan AU - Yanagisawa, K. AU - Muneta, T. AU - Ozeki, N. AU - Nakagawa, Y. AU - Udo, M. AU - Saito, R. AU - Koga, H. AU - Tsuji, K. AU - Sekiya, I. C7 - 188 DB - Scopus DO - 10.1186/s12891-016-1051-6 IS - 1 KW - Hyaluronan Hylan G-F 20 Osteoarthritis Partial meniscectomy Rat M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2016 ST - Weekly injections of Hylan G-F 20 delay cartilage degeneration in partial meniscectomized rat knees T2 - BMC Musculoskeletal Disorders TI - Weekly injections of Hylan G-F 20 delay cartilage degeneration in partial meniscectomized rat knees UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84966443160&doi=10.1186%2fs12891-016-1051-6&partnerID=40&md5=e4821237371fb3a4817f286729b02a49 VL - 17 ID - 1186 ER - TY - JOUR AN - 106232540. Language: English. Entry Date: 20070209. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 192 KW - Surgical Count Procedure -- Equipment and Supplies Radio Frequency Identification Surgical Sponges N1 - brief item. Journal Subset: Allied Health; Blind Peer Reviewed; Europe; Nursing; Peer Reviewed; UK & Ireland. PY - 2006 SN - 1747-728X SP - 13-13 ST - Wand spots swabs left in patient T2 - Operating Theatre Journal TI - Wand spots swabs left in patient UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106232540&site=ehost-live&scope=site ID - 936 ER - TY - JOUR AB - Aim: In adults modern vitreoretinal surgery allows many traumatised eyes to be salvaged. However, one third of serious eye injuries occur in the paediatric age group and trauma is a leading cause of monocular blindness in childhood. This study aims to report the indications, complications and outcomes for vitreoretinal surgical intervention after childhood ocular trauma. Methods: Retrospective case note review of 61 children (age 16 years or less) undergoing vitreoretinal surgical procedures following ocular trauma at a tertiary referral centre. Results: Twenty-eight children (45.9%) had open globe injuries (OGI) and 33 closed globe injuries (CGI, 54.1%). The mean age of children with OGI was 9.5 years and with CGI 12.3 years (P=0.0068). Forty-seven children had traumatic retinal detachments (77.1%), which in 17 cases were treated with conventional scleral buckling surgery and in 30 by vitrectomy. Retinal re-attachment was achieved after one procedure in 70.6% with scleral buckling and 46.7% with vitrectomy. Fourteen children (22.9%) had attached retinas but required vitrectomy for other reasons. After a mean follow-up of 19.6 months, the median visual acuity (VA) of the children improved from counting fingers at presentation to 6/36 at final review (P=0.0031). Traumatic retinal detachment requiring vitrectomy was associated with poor visual outcome (P=0.0003). Conclusion: Vitreoretinal intervention resulted in an improvement in vision in 32 children (57.1%) and stabilised 11 at their presenting acuity (19.6%). Two thirds of the children attained a final VA of 6/60 or better. Proliferative vitreoretinopathy was the cause of redetachment in 68.2% of cases and was significantly associated with a poor outcome (P<0.0001). AD - Moorfields Eye Hospital, City Road, London, United Kingdom AU - Sheard, R. M. AU - Mireskandari, K. AU - Ezra, E. AU - Sullivan, P. M. DB - Scopus DO - 10.1038/sj.eye.6702332 IS - 6 M3 - Article N1 - Cited By :29 Export Date: 10 November 2020 PY - 2007 SP - 793-798 ST - Vitreoretinal surgery after childhood ocular trauma T2 - Eye TI - Vitreoretinal surgery after childhood ocular trauma UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-34250304356&doi=10.1038%2fsj.eye.6702332&partnerID=40&md5=b9329a66c1896f9eea6ee7b0a5e0687a VL - 21 ID - 1573 ER - TY - JOUR AB - Poly(etherurethane) elastomers are useful materials in medical devices because of their mechanical properties and biocompatibility. However, it is necessary to stabilize these elastomers against the oxidation of their ether soft segments. Synthetic antioxidants such as Santowhite® and Irganox® are often satisfactory; however, particularly for biomedical applications, it was of interest to test the natural antioxidant vitamin E in poly(etherurethane urea) (PEUU) elastomers in vivo. The α-tocopherol form of vitamin E was added to PEUU at 5% by weight. Biaxially strained PEUU specimens with and without vitamin E were tested in vivo in the cage implant system. The influence of vitamin E on PEUU biostability was analyzed by attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy and scanning electron microscopic (SEM) characterization of the PEUU surface. ATR-FTIR results showed that vitamin E prevented chemical degradation of the PEUU surface up to 5 weeks implantation, and at 10 weeks 82% of the ether remained. In contrast, without an antioxidant, only 18% of the ether remained after 10 weeks. No surface pitting or cracking was observed by SEM on PEUU with vitamin E; PEUU without antioxidant ruptured owing to extensive pitting and cracking. It was concluded that the antioxidant properties of vitamin E prevented oxidation of strained PEUU elastomers in vivo. The influence of vitamin E on PEUU biocompatibility was characterized by exudate leukocyte counts, density of leukocytes adherent to the PEUU, and morphology of adherent leukocytes. These results indicated decreased leukocyte counts in the exudate and less active adherent cells on the PEUU with vitamin E compared to PEUU without antioxidant. A proposed cell-polymer feedback system demonstrates how vitamin E improves both biostability and biocompatibility of PEUU elastomers in vivo. Poly(etherurethane) elastomers are useful materials in medical devices because of their mechanical properties and biocompatibility. However, it is necessary to stabilize these elastomers against the oxidation of their ether soft segments. Synthetic antioxidants such as Santowhite and Irganox are often satisfactory; however, particularly for biomedical applications, it was of interest to test the natural antioxidant vitamin E in poly(etherurethane urea) (PEUU) elastomers in vivo. The α-tocopherol form of vitamin E was added to PEUU at 5% by weight. Biaxially strained PEUU specimens with and without vitamin E were tested in vivo in the cage implant system. The influence of vitamin E on PEUU biostability was analyzed by attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy and scanning electron microscopic (SEM) characterization of the PEUU surface. ATR-FTIR results showed that vitamin E prevented chemical degradation of the PEUU surface up to 5 weeks implantation, and at 10 weeks 82% of the ether remained. In contrast, without an antioxidant, only 18% of the ether remained after 10 weeks. No surface pitting or cracking was observed by SEM on PEUU with vitamin E; PEUU without antioxidant ruptured owing to extensive pitting and cracking. It was concluded that the antioxidant properties of vitamin E prevented oxidation of strained PEUU elastomers in vivo. The influence of vitamin E on PEUU biocompatibility was characterized by exudate leukocyte counts, density of leukocytes adherent to the PEUU, and morphology of adherent leukocytes. These results indicated decreased leukocyte counts in the exudate and less active adherent cells on the PEUU with vitamin E compared to PEUU without antioxidant. A proposed cell-polymer feedback system demonstrates how vitamin E improves both biostability and biocompatibility of PEUU elastomers in vivo. AD - Department of Macromolecular Science, Case Western Reserve University, Cleveland, OH 44106, United States Institute of Pathology, Case Western Reserve University, Cleveland, OH 44106, United States AU - Schubert, M. A. AU - Wiggins, M. J. AU - DeFife, K. M. AU - Hiltner, A. AU - Anderson, J. M. DB - Scopus DO - 10.1002/(SICI)1097-4636(199612)32:4<493::AID-JBM1>3.3.CO;2-H IS - 4 M3 - Article N1 - Cited By :41 Export Date: 10 November 2020 PY - 1996 SP - 493-504 ST - Vitamin E as an antioxidant for poly(etherurethane urea): In vivo studies T2 - Journal of Biomedical Materials Research TI - Vitamin E as an antioxidant for poly(etherurethane urea): In vivo studies UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030561156&doi=10.1002%2f%28SICI%291097-4636%28199612%2932%3a4%3c493%3a%3aAID-JBM1%3e3.3.CO%3b2-H&partnerID=40&md5=9a2b7df78dbd165e6522924000c7cb6d VL - 32 ID - 1713 ER - TY - JOUR AB - Porous polyethylene (Medpor®) is frequently used in craniofacial reconstructive surgery. The successful incorporation of this alloplastic biomaterial depends on adequate vascularization. Here, we analyzed whether the early vascularization of porous polyethylene can be accelerated by vitalization with human chondrocytes. For this purpose, small polyethylene samples were coated with platelet-rich plasma (PRP) or a suspension of PRP and human chondrocytes. Uncoated polyethylene samples served as controls. Subsequently, the samples were implanted into the dorsal skinfold chamber of CD-1 nude mice to repetitively analyze their vascularization and biocompatibility by means of intravital fluorescence microscopy. PRP-chondrocyte-coated polyethylene exhibited an accelerated and improved vascularization when compared with the other two groups. This was indicated by a significantly higher functional capillary density of the microvascular network developing around the implants. Moreover, a leukocyte-endothelial cell interaction was found in a physiological range at the implantation site of all three groups, demonstrating that the vitalization with PRP and chondrocytes did not affect the good biocompatibility of the alloplastic material. Additional histological, immunohistochemical, and in situ hybridization analyses revealed that the chondrocytes formed a bioprotective tissue layer, which prevented the accumulation of macrophages and foreign body giant cells on the polyethylene surface. These findings clearly indicate that vitalization of polyethylene with chondrocytes promotes early implant vascularization and incorporation into the host tissue and, thus, may be a promising approach that prevents postoperative complications such as implant extrusion, migration, and infection. © 2012 Copyright, Mary Ann Liebert, Inc. AD - Institute for Clinical and Experimental Surgery, University of Saarland, Homburg/Saar, D-66421, Germany Department of Small Animal Surgery, Ludwig-Maximilians-University, Munich, Germany Department of Otorhinolaryngology, Head and Neck Surgery, University of Saarland, Homburg/Saar, Germany Department of Otorhinolaryngology, Klinikum Bremen-Mitte GGmbH, Bremen, Germany AU - Ehrmantraut, S. AU - Naumann, A. AU - Willnecker, V. AU - Akinyemi, S. AU - Körbel, C. AU - Scheuer, C. AU - Meyer-Lindenberg, A. AU - Menger, M. D. AU - Laschke, M. W. DB - Scopus DO - 10.1089/ten.tea.2011.0340 IS - 15-16 M3 - Article N1 - Cited By :15 Export Date: 10 November 2020 PY - 2012 SP - 1562-1572 ST - Vitalization of porous polyethylene (Medpor®) with chondrocytes promotes early implant vascularization and incorporation into the host tissue T2 - Tissue Engineering - Part A TI - Vitalization of porous polyethylene (Medpor®) with chondrocytes promotes early implant vascularization and incorporation into the host tissue UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84865209918&doi=10.1089%2ften.tea.2011.0340&partnerID=40&md5=1f9748c2ac022124fc7c809057b3d433 VL - 18 ID - 1363 ER - TY - JOUR AB - OBJECTIVE: To assess the visual outcome and complications after removal of posterior segment retained intraocular foreign bodies through pars plana approach. STUDY DESIGN: Case series. PLACE AND DURATION OF STUDY: Department of Ophthalmology, Jinnah Postgraduate Medical Centre, Karachi, from May 2005 to May 2006. METHODOLOGY: Fifty patients with history of ocular foreign body were admitted through outpatient department and emergency. History, visual acuity, ocular and general examination was done. The foreign body was localized with the radiograph of the skull and ultrasonography. Primary repair was done in patients with open wounds. Pars plana vitrectomy, magnetic or forceps extraction of foreign body was done as required visual outcomes and complications were noted. RESULTS: Among the 50 patients, there were 45 (90%) males and 5 (10%) females. Average age of the patients was 31.52 +9.52 (ranging from 20 to 50) years. The pre-operatively visual acuity finger counting to perception of light was 78% cases. The best corrected final visual acuity was 6/6 in 1 (2%) patient, 6/9 in 5 (10%) patients, 6/12 in 5 (10%) patients, 6/18 in 3 (6%) patients, 6/24 and 6/36 in 4 (8%) patients each, 6/60 in 4 (8%) patients, finger counting in 8 (16%) patients, hand movement in 4 (8%) patients, projection of light in 9 (18%) patients and no projection of light in 3 (6%) patients. The postoperative complications were corneal opacity in 8 (16%) patients, anterior chamber inflammatory reaction in 6 (12%) patients, increased intraocular pressure in 1 (2%) patient, silicone oil in anterior chamber in 1 (2%) patient, macular scar in 7 (14%) patients, cystoid macular edema in 1 (2%) patient, endophthalmitis in 4 (8%) patients, retinal detachment in 11 (22%) patients and phthisis bulbi in 3 (6%) patients. CONCLUSION: Acceptable visual results were achieved after the removal of posterior segment intraocular foreign bodies by vitrectomy. However, multiple complications can be encountered which require meticulate postoperative care. AD - Department of Ophthalmology, Jinnah Postgraduate Medical Centre, Karachi. AN - 19576152 AU - Memon, A. A. AU - Iqbal, M. S. AU - Cheema, A. AU - Niazi, J. H. DA - Jul DP - NLM ET - 2009/07/07 IS - 7 KW - Adult Eye Foreign Bodies/*surgery Female Humans Male Middle Aged Visual Acuity *Vitrectomy/adverse effects Young Adult LA - eng N1 - Memon, Ameer Ahmed Iqbal, M Saeed Cheema, Alyscia Niazi, Javed Hassan Journal Article Pakistan J Coll Physicians Surg Pak. 2009 Jul;19(7):436-9. PY - 2009 SN - 1022-386X (Print) 1022-386x SP - 436-9 ST - Visual outcome and complications after removal of posterior segment intraocular foreign bodies through pars plana approach T2 - J Coll Physicians Surg Pak TI - Visual outcome and complications after removal of posterior segment intraocular foreign bodies through pars plana approach VL - 19 ID - 92 ER - TY - JOUR AB - PURPOSE: This article reports the presentation, management, and outcomes in patients suffering perforating ocular injuries. METHODS: A retrospective review was conducted at a single ophthalmology Level 1 trauma center. Patients with evidence of traumatic ocular perforation, with surgical intervention attended by a single vitreoretinal surgeon (W.F.M.), were reviewed between 2009 and 2017. RESULTS: Six eyes from 6 patients with perforating ocular injuries were studied. All patients were male, between ages 11 and 56 years. Perforation was the result of gunshots (3), other accidental injury (2), or surgical complication (1). Varying degrees of retinal detachments were seen in all 6 patients. Pars plana vitrectomy, with endolaser around posterior entry or exit wounds, was performed on average 21.7 ± 8.9 days from the time of injury (range, 0-58 days). In all cases with intraorbital foreign bodies, the foreign bodies were left in place. The most recent postoperative visual acuity ranged from 20/25 to counting fingers. Missile injuries tended to have poorer vision. All cases achieved full anatomic attachment at most recent follow-up. There have been no orbital complications related to retained intraorbital foreign bodies, including endophthalmitis, orbital infections, or mechanical strabismus. CONCLUSION: This study demonstrates successful anatomic outcomes of 6 cases of perforating ocular injuries. Visual outcomes were variable, though missile injuries demonstrated worse prognosis, whereas several nonmissile macula-involving cases achieved quite favorable results. Although traumatic perforating injuries generally have guarded visual prognoses, favorable results may be achieved in select scenarios. AD - Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, USA. AN - 31742242 AU - Kanu, L. N. AU - Jiang, Y. AU - Gonzalez, A. F. AU - Mieler, W. F. C2 - PMC6859898 C6 - NIHMS1050167 DA - Nov DO - 10.1177/2474126419865992 DP - NLM ET - 2019/11/20 IS - 6 KW - double-penetrating double-perforating foreign bodies foreign body open-globe injury perforating through and through interest with respect to the research, authorship, and/or publication of this article. LA - eng N1 - 2474-1272 Kanu, Levi N Orcid: 0000-0001-6428-4696 Jiang, Yi Gonzalez, Alvaro Fernandez-Vega Mieler, William F P30 EY001792/EY/NEI NIH HHS/United States Journal Article J Vitreoretin Dis. 2019 Nov;3(6):428-437. doi: 10.1177/2474126419865992. Epub 2019 Sep 11. PY - 2019 SN - 2474-1264 (Print) 2474-1264 SP - 428-437 ST - Visual and Anatomic Outcomes in Perforating Ocular Injuries T2 - J Vitreoretin Dis TI - Visual and Anatomic Outcomes in Perforating Ocular Injuries VL - 3 ID - 235 ER - TY - JOUR AB - Background: Orbital fracture usually occurs as a result of blunt orbital and facial trauma and may involve ocular injuries. International studies on orbital floor fracture show several differences in epidemiology, diagnostic criteria, surgical treatment modalities, and complication rates; therefore, any comparison should be made with caution. Here we describe an unusual case involving a 19-year-old man with violence-related periorbital trauma, wherein a foreign body (a plastic pen cap) traversed the median wall of the maxillary sinus and penetrated the lower turbinate. Case presentation: A 19-year-old Caucasian man was referred to our department with localized pain and swelling in the left suborbital region following a physical fight in May 2014. A clinical examination revealed no abnormalities in his eyeballs or eye movement, palpation of the orbital contour revealed no fractures, and ophthalmological evaluation showed no evidence of diplopia. A computed tomography scan revealed fractures in the left orbital floor, periorbital tissue herniation without muscular entrapment and left maxillary hemosinus were observed. A hypodense soft tissue mass was lodged in the left orbital floor, which extended to the median wall of the maxillary sinus and penetrated the left lower turbinate. Surgical exploration of the foreign body was conducted, revealing the foreign body to be a pen cap. Conclusions: History or clinical examination alone may be inadequate to raise the suspicion of a retained periorbital foreign body in a situation of orbital region trauma. Computed tomography is important for the evaluation of periorbital injuries, especially because it could reveal the presence of a foreign body. Periorbital foreign bodies can be observed distinctly on computed tomography, which remains the most sensitive study and should be the first imaging modality in such cases. © 2016 Dell'Aversana et al. AD - Division of Maxillofacial Surgery, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Via Pansini, 5, Naples, 80131, Italy Oral Surgery Division, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Via Pansini, 5, Naples, 80131, Italy Ear, Nose and Throat Department, Second University of Naples, Via Pansini, 5, Naples, 80131, Italy Maxillofacial Department, University of Sassari, Viale San Pietro, 43/B, Sassari, 07100, Italy AU - Dell'Aversana, G. AU - Marenzi, G. AU - Piombino, P. AU - Testa, D. AU - De Riu, G. AU - Abbate, V. AU - Califano, L. AU - Sammartino, G. C7 - 16 DB - Scopus DO - 10.1186/s13256-015-0779-1 IS - 1 KW - Blunt trauma Computed tomography Foreign body Hemosinus Orbital floor fracture M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2016 ST - Violence-related periorbital trauma with a retained foreign body: A case report T2 - Journal of Medical Case Reports TI - Violence-related periorbital trauma with a retained foreign body: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84958102300&doi=10.1186%2fs13256-015-0779-1&partnerID=40&md5=51c56d146a1a3f1946b61b299bfe3f1c VL - 10 ID - 1195 ER - TY - JOUR AB - The use of Lucite balls or spheres played a role in the management of tuberculosis during the first decade of the 20th century. Several complications have been reported with the use of this surgical technique, but are rarely seen nowadays. The availability of effective oral regimens has forced to abandon this approach. Calcification of these spheres within the lung cavity produced a series of late complications result of the migration of these foreign bodies to adjacent structures, causing erosion of blood vessels and nerves. Herein, we present a case where the aforementioned complication caused significant bleeding with hemodynamic instability. The source of the profuse hemoptysis was identified and was resolved with the combined use of noninvasive approaches such as bronchoscopy and angiographic embolization. Copyright © 2016 by Thieme Medical Publishers, Inc. AD - Division of Nephrology and Hypertension, Department of Medicine, Brookdale University Hospital and Medical Center, 1 Brookdale Plaza, Brooklyn, NY 11212, United States Division of Pulmonary/Critical Care and Infectious Disease, University of Mississippi Medical Center, Jackson, MS, United States Medicine Division, NYU School of Medicine, New York, NY, United States Division of Cardiology, Woodhull Medical Center, Brooklyn, NY, United States AU - Loarte, P. AU - Holguín, G. AU - Cohen, R. DB - Scopus DO - 10.1055/s-0034-1382811 IS - 5 KW - embolization hemoptysis Lucite spheres tuberculosis M3 - Article N1 - Export Date: 10 November 2020 PY - 2016 SP - e60-e62 ST - A Very Unusual Cause of Hemoptysis T2 - International Journal of Angiology TI - A Very Unusual Cause of Hemoptysis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84905295070&doi=10.1055%2fs-0034-1382811&partnerID=40&md5=6e424268def6a98aaaa3a729ce111e82 VL - 25 ID - 1165 ER - TY - JOUR AB - A 56-year-old man presented acutely with abdominal pain and raised inflammatory markers. Initial CT images demonstrated acute inflammation in the right upper quadrant surrounding a high-density linear structure. The appearance was of a chicken bone causing a contained small bowel perforation. This was managed conservatively with intravenous antibiotics and the patient was discharged 10 days later. The same patient returned to the hospital 2 months later, once again with an acute abdomen. CT imaging on this occasion showed distal migration of the chicken bone as well as free gas and fluid indicative of a new small bowel perforation. The patient underwent an emergency laparotomy, washout and small bowel resection. No foreign body was found at laparotomy or in the histopathology specimen. The postoperative course was complicated by an anastomotic leak. A further CT on that admission demonstrated that the chicken bone had migrated to the rectum! © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ. AD - General Surgery, Kingston Hospital NHS Foundation Trust, Kingston upon Thames, London, United Kingdom AU - Brown, A. J. AU - Whitehead-Clarke, T. AU - Tudyka, V. C7 - e228050 DB - Scopus DO - 10.1136/bcr-2018-228050 IS - 5 KW - gastrointestinal surgery general surgery M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 ST - A very persistent chicken bone: Two separate perforations from the same foreign object 2 months apart T2 - BMJ Case Reports TI - A very persistent chicken bone: Two separate perforations from the same foreign object 2 months apart UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065923263&doi=10.1136%2fbcr-2018-228050&partnerID=40&md5=e1830fc199942f6d8ead4c2eafe10c4b VL - 12 ID - 1014 ER - TY - JOUR AB - Implantable continuous biosensors would improve disease management but long term function of such devices have been limited by a hypovascular foreign body capsule that inhibits influx of analytes. To assess whether capsule vascularity could be increased, we studied the histologic effects of a 28-day continuous infusion of vascular endothelial growth factor (VEGF) (0.45 μg/day) vs. saline from the surface of a model disk biosensor that was implanted subcutaneously in rats. At day 40, tissue was obtained at varying distances from the infusion port and capsular microvessels were counted using two histologic techniques. VEGF treatment led to a marked increase in capillary density. In tissue located 1 mm away from the infusion site, capillary density in VEGF-treated animals was 200-300% higher than in saline controls. Tissue located 13 mm away, but not 25 mm away, also demonstrated neovascularization. Serum obtained from a distant vein during the infusion did not show an elevated concentration of VEGF. These data demonstrate that a subcutaneous infusion of VEGF creates localized neovascularization of the foreign body capsule and suggest that systemic effects of VEGF are avoidable. Vascularization of a foreign body capsule surrounding a subcutaneous biosensor might well extend its useful life. © 2003 Elsevier B.V. All rights reserved. AD - Legacy Health System, Legacy Clin. Res./Technology Center, 1225 NE 2nd Avenue, Portland, OR 97232, United States AU - Ward, W. K. AU - Quinn, M. J. AU - Wood, M. D. AU - Tiekotter, K. L. AU - Pidikiti, S. AU - Gallagher, J. A. DB - Scopus DO - 10.1016/S0956-5663(03)00180-5 IS - 3 KW - Angiogenesis Foreign body capsule Glucose sensor VEGF M3 - Article N1 - Cited By :45 Export Date: 10 November 2020 PY - 2003 SP - 155-163 ST - Vascularizing the tissue surrounding a model biosensor: How localized is the effect of a subcutaneous infusion of vascular endothelial growth factor (VEGF)? T2 - Biosensors and Bioelectronics TI - Vascularizing the tissue surrounding a model biosensor: How localized is the effect of a subcutaneous infusion of vascular endothelial growth factor (VEGF)? UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0242637447&doi=10.1016%2fS0956-5663%2803%2900180-5&partnerID=40&md5=9753e11c13a68b0db69b12ed596fe1f3 VL - 19 ID - 1640 ER - TY - JOUR AB - INTRODUCTION AND OBJECTIVE: Retained foreign objects (RFO) after surgery are a serious and preventable issue. Gawande et al (2003) found that the incidence of RFOs in 22 hospitals ranged from 1 in 8,801 to 1 in 18,760 and that retained vaginal sponges accounted for 22% of all retained foreign bodies. Although rare, these events can have severe consequences for both the patients, providers, and hospitals, and can often lead to litigation. We performed a human factors analysis, which is the discipline of studying the interactions of humans and systems, to understand and develop interventions that may help prevent vaginal RFOs. METHODS: We analyzed the safety events reported to our internal tracking system from January 1, 2000 - May 21, 2019 and filtered specifically by potential and actual vaginal RFOs. These events were then categorized into vaginal RFO “Near Misses” (RFO identified before patient leaves the OR) and “Sentinel Events” (RFO not identified before patient leaves the OR). The event reports were then analyzed by three trained human factors researchers. The conditions surrounding each event were analyzed and categorized into the Human Factors Analysis and Classification System (HFACS). RESULTS: 45 events were reported in the 19-year period. The majority of the events analyzed were categorized as “near misses.” The most common items in question (53.33%) were Raytecs, vaginal packing, and vaginal sponges. However, another common instance was breaking of an instrument (20.20%) while operating in the vagina. The majority of cases were laparoscopic hysterectomies or vaginal deliveries. Based on our human factors analysis, the most common contributing factor involved skill-based errors, such as counting errors, followed by issues with communication and shortcomings in the design of tools/technologies (see Table 1). CONCLUSIONS: Fortunately, the occurrence of vaginal RFOs is rare. According to our analysis, the top two contributing factors are skill-based errors and communication, neither of which would have been addressed without the application of a human factors approach. Moreover, both types of errors can be addressed and improved with human factors interventions such as simulation and teamwork training to streamline workflow to reduce the opportunity for errors. (Table Presented). AD - C.P. Souders, Los Angeles, CA, United States AU - Souders, C. P. AU - Cohen, T. AU - Dallas, K. AU - Cohen, K. AU - Kanji, F. AU - Stewart, C. AU - Anger, J. DB - Embase DO - 10.1097/JU.0000000000000819.020 KW - adult conference abstract contraceptive sponge female human hysterectomy plant leaf sentinel event simulation skill teamwork vaginal delivery workflow LA - English M3 - Conference Abstract N1 - L632062365 2020-07-30 PY - 2020 SN - 1527-3792 SP - e49-e50 ST - Vaginal retained foreign objects: Applying a human factors perspective T2 - Journal of Urology TI - Vaginal retained foreign objects: Applying a human factors perspective UR - https://www.embase.com/search/results?subaction=viewrecord&id=L632062365&from=export http://dx.doi.org/10.1097/JU.0000000000000819.020 VL - 203 ID - 280 ER - TY - JOUR AB - Introduction: Retained foreign objects (RFO) after surgery are a serious and preventable issue. Gawande et al (2003) found that the incidence of RFOs in 22 hospitals ranged from 1 in 8,801 to 1 in 18,760 and that retained vaginal sponges accounted for 22% of all retained foreign bodies. Although rare, these events can have severe consequences for both the patients, providers, and hospitals, and can often lead to litigation. We performed a human factors analysis, which is the discipline of studying the interactions of humans and systems, to understand and develop interventions that may help prevent vaginal RFOs. Methods: We analyzed the safety events reported to our internal tracking system from January 1, 2000 - May 21, 2019 and filtered specifically by potential and actual vaginal RFOs. These events were then categorized into vaginal RFO 'Near Misses' (RFO identified before patient leaves the OR) and 'Sentinel Events' (RFO not identified before patient leaves the OR). The event reports were then analyzed by three trained human factors researchers. The conditions surrounding each event were analyzed and categorized into the Human Factors Analysis and Classification System (HFACS). Results: 45 events were reported in the 19-year period. The majority of the events analyzed were categorized as 'near misses.' The most common items in question (53.33%) were Raytecs, vaginal packing, and vaginal sponges. However, another common instance was breaking of an instrument (20.20%) while operating in the vagina. The majority of cases were laparoscopic hysterectomies or vaginal deliveries. Based on our human factors analysis, the most common contributing factor involved skill-based errors, such as counting errors, followed by issues with communication and shortcomings in the design of tools/ technologies (see Table 1). Conclusion: Fortunately, the occurrence of vaginal RFOs is rare. According to our analysis, the top two contributing factors are skill-based errors and communication, neither of which would have been addressed without the application of a human factors approach. Moreover, both types of errors can be addressed and improved with human factors interventions such as simulation and teamwork training to streamline workflow to reduce the opportunity for errors. (Table Presented). AD - C. Souders, Cedars-Sinai Medical Center AU - Souders, C. AU - Cohen, T. AU - Dallas, K. AU - Cohen, K. AU - Kanji, F. AU - Stewart, C. AU - Anger, J. T. DB - Embase DO - 10.1002/nau.24307 KW - adult conference abstract contraceptive sponge female human hysterectomy plant leaf sentinel event simulation skill teamwork vaginal delivery workflow LA - English M3 - Conference Abstract N1 - L632157644 2020-07-27 PY - 2020 SN - 1520-6777 SP - S160-S161 ST - Vaginal retained foreign objects: Applying a human factors perspective T2 - Neurourology and Urodynamics TI - Vaginal retained foreign objects: Applying a human factors perspective UR - https://www.embase.com/search/results?subaction=viewrecord&id=L632157644&from=export http://dx.doi.org/10.1002/nau.24307 VL - 39 ID - 289 ER - TY - CHAP AB - Vaginal foreign bodies present in female patients of all ages and a wide range of healthcare settings, to include the emergency department, primary care office, gynecology office, and urology office. The objects found differ among age groups. Toys, tissue paper, and household objects are the most common in pediatrics. In adult women, considerations include tampons, condoms, menstrual cups, and items used for sexual gratification. Elderly patients are at increased risk for retained medical devices such as pessaries. Patient populations such as prisoners and drug traffickers may use the vaginal canal and uterus to hide illicit substances. In postpartum patients with recurrent abdominal pain, pelvic abscess, bladder stones, irritable bladder, and retained surgical gauze merit consideration; however, this is an unusual complication due to patient safety initiatives involving the careful counting of surgical gauze and sponges during delivery. Patients may self report a foreign body or may present with an array of symptoms, including pelvic pain, vaginal discharge, and vaginal bleeding. There is a broad differential diagnosis for these symptoms, including malignancy, sexually transmitted infections, candidal infections, and pregnancy. The most common presenting symptom in pediatric patients is vaginal bleeding or discharge. When evaluating a patient who suspects a vaginal foreign body, history should focus on the details surrounding the initial event; this includes timing, the suspected object, and symptoms of the abdomen, pelvis, and genitalia. History taking is imperative in all patient populations. Even in pediatric patients, the majority, 54% in one study, recall the event. It is essential to consider sexual abuse as a cause for foreign bodies, especially in the pediatric population. AD - Jefferson Northeast AN - 31747201 AU - Anderson, J. AU - Paterek, E. CY - Treasure Island (FL) LA - eng N1 - Anderson, Jackie Paterek, Elizabeth Review Book Chapter NBK549794 [bookaccession] PB - StatPearls Publishing Copyright © 2020, StatPearls Publishing LLC. PY - 2020 ST - Vaginal Foreign Body Evaluation and Treatment T2 - StatPearls TI - Vaginal Foreign Body Evaluation and Treatment ID - 249 ER - TY - JOUR AB - PURPOSE: To evaluate the long-term response of 6 types of 3-piece intraocular lenses (IOLs) by assessing the cellular reaction on the anterior IOL surface, the behavior of posterior and anterior capsule fibrosis, and flare. SETTING: Department of Ophthalmology, Medical School, University of Vienna, Vienna, Austria. METHODS: One hundred eighty eyes were prospectively randomized to receive 1 of 6 IOLs: hydrophilic acrylic Hydroview (Bausch & Lomb) or MemoryLens (ORC); hydrophobic acrylic AcrySof MA60BM (Alcon) or AMO Sensar AR40 (Allergan); hydrophobic silicone CeeOn 920 or CeeOn 911A (Pharmacia). The patients had standardized cataract surgery, postoperative medication, and follow-up. One year after surgery, 155 eyes were assessed. The cellular reaction was evaluated by specular microscopy of the anterior IOL surface. Anterior and posterior capsule opacification (PCO) was assessed semiquantitatively by biomicroscopy. Flare was measured with a Kowa FC-1000 laser flare-cell meter. RESULTS: Regarding uveal biocompatibility, the hydrophobic acrylic IOLs showed the highest incidence of late foreign-body cell reaction (AcrySof, 30%; AR40, 17%) followed by the hydrophilic acrylic (MemoryLens, 8%; Hydroview, 4%) and silicone (CeeOn 920, 4%; CeeOn 911A, 0%) (P =.0044). In all cases, the cellular reaction was low grade and clinically insignificant. Regarding capsular biocompatibility, some eyes developed lens epithelial cell (LEC) outgrowth on the anterior IOL surface. The highest incidence was in the hydrophilic acrylic group (Hydroview, 85%; MemoryLens, 27%) followed by the hydrophobic acrylic (AcrySof, 4%; AR40, 3%). No silicone IOL had LECs on the anterior surface. The difference among IOL groups was significant (P =.0001). Anterior capsule opacification was more predominant in the hydrophobic IOL groups. Posterior capsule opacification of the central 3.0 mm area was lowest in the groups with a sharp-edged optic (CeeOn 911A, AcrySof) followed by the round-edged silicone (CeeOn 920), hydrophobic acrylic (AR40), and hydrophilic acrylic IOLs (P =.0001). There was a significant difference in flare between the AR40 lens and the Hydroview, MemoryLens, CeeOn 911A, and CeeOn 920 (P <.004). There was no statistically significant difference in the postoperative cell count at 1 year. The power calculation showed that the sample size was sufficient. CONCLUSIONS: The differences in cellular reaction, although clinically mild in normal eyes, indicate that there were more giant cells with hydrophobic acrylic IOLs and an increased tendency toward LEC outgrowth with hydrophilic lenses. The incidence of PCO was lowest in the hydrophobic IOL groups, especially in groups with a sharp-edged optic. Second-generation silicone IOLs with a sharp edge had good uveal and capsular biocompatibility 1 year after surgery. AD - Department of Ophthalmology, Medical School, University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. claudette.abela-formanek@akh-wien.ac.at AN - 11777710 AU - Abela-Formanek, C. AU - Amon, M. AU - Schild, G. AU - Schauersberger, J. AU - Heinze, G. AU - Kruger, A. DA - Jan DO - 10.1016/s0886-3350(01)01122-1 DP - NLM ET - 2002/01/05 IS - 1 KW - Acrylic Resins/adverse effects Aged Biocompatible Materials/*adverse effects Capsulorhexis Cataract/*etiology Epithelial Cells/pathology Female Fibrosis Foreign-Body Reaction/*etiology Giant Cells/pathology Humans Hydrophobic and Hydrophilic Interactions Lens Capsule, Crystalline/*pathology Lens Implantation, Intraocular Lenses, Intraocular/*adverse effects Male Phacoemulsification Prospective Studies Silicone Elastomers/adverse effects Uveal Diseases/*etiology/pathology LA - eng N1 - Abela-Formanek, Claudette Amon, Michael Schild, Gebtraud Schauersberger, Jörg Heinze, Georg Kruger, Andreas Clinical Trial Comparative Study Journal Article Randomized Controlled Trial United States J Cataract Refract Surg. 2002 Jan;28(1):50-61. doi: 10.1016/s0886-3350(01)01122-1. PY - 2002 SN - 0886-3350 (Print) 0886-3350 SP - 50-61 ST - Uveal and capsular biocompatibility of hydrophilic acrylic, hydrophobic acrylic, and silicone intraocular lenses T2 - J Cataract Refract Surg TI - Uveal and capsular biocompatibility of hydrophilic acrylic, hydrophobic acrylic, and silicone intraocular lenses VL - 28 ID - 35 ER - TY - JOUR AB - PURPOSE: To analyze uveal and capsular biocompatibility 1 year following implantation of a sharp-edged, hydrophilic, collagen-containing posterior chamber intraocular lens (IOL). SETTING: Department of Ophthalmology, University of Vienna Medical School, Vienna, Austria. METHOD: In a prospective study, a Collamer CC4204BF IOL was implanted in 30 eyes of patients with senile cataract. A standardized surgical technique and postoperative regimen were applied. To assess uveal biocompatibility, cellular inflammation on the anterior IOL surface was evaluated with a specular microscope. Capsular biocompatibility was registered semiquantitatively with a biomicroscope, based on an assessment of fibrosis on the anterior and posterior capsules. Tyndall values were measured with the Kowa FC-1000 laser flare-cell meter. Decentration of the lens was also registered. RESULTS: One year after implantation, the values of flare and cell count in the anterior chamber were lower than preoperatively. Round and spindle-shaped, epithelioid, and foreign-body giant cells were not found on the anterior surface of the IOL. The capsulorhexis rim was moderately fibrosed in 56.6% of cases. Fibrosis of the capsule over the optic was also moderate in 36.6%. The central portion of the posterior capsule was devoid of fibrosis in 43.3% and mildly fibrosed in 50%. Three lenses revealed outgrowth of lens epithelial cells to the anterior surface of the IOL. A neodymium:YAG capsulotomy had to be performed in 1 case. All lenses were well centered in the capsular bag 1 year after implantation. CONCLUSIONS: The absence of inflammatory cells on the anterior surface of the IOL indicates the high uveal biocompatibility of the lens. In terms of capsular biocompatibility, the results were satisfactory. AD - Department of Ophthalmology, University of Vienna, Medical School, Vienna, Austria. AN - 15177600 AU - Schild, G. AU - Amon, M. AU - Abela-Formanek, C. AU - Schauersberger, J. AU - Bartl, G. AU - Kruger, A. DA - Jun DO - 10.1016/j.jcrs.2003.11.041 DP - NLM ET - 2004/06/05 IS - 6 KW - *Biocompatible Materials Cell Count *Collagen Female Fibrosis Foreign-Body Reaction/prevention & control Giant Cells/pathology Humans Lens Capsule, Crystalline/*pathology Lens Diseases/*prevention & control Lens Implantation, Intraocular *Lenses, Intraocular Male Phacoemulsification *Polyhydroxyethyl Methacrylate Prospective Studies Prosthesis Design Uveal Diseases/*prevention & control LA - eng N1 - Schild, Gebtraud Amon, Michael Abela-Formanek, Claudette Schauersberger, Jörg Bartl, Gustav Kruger, Andreas Journal Article United States J Cataract Refract Surg. 2004 Jun;30(6):1254-8. doi: 10.1016/j.jcrs.2003.11.041. PY - 2004 SN - 0886-3350 (Print) 0886-3350 SP - 1254-8 ST - Uveal and capsular biocompatibility of a single-piece, sharp-edged hydrophilic acrylic intraocular lens with collagen (Collamer): 1-year results T2 - J Cataract Refract Surg TI - Uveal and capsular biocompatibility of a single-piece, sharp-edged hydrophilic acrylic intraocular lens with collagen (Collamer): 1-year results VL - 30 ID - 48 ER - TY - JOUR AB - Four decades ago, perioperative nursing transitioned from a task‐oriented and problem‐focused specialty to a patient‐centered discipline. This transition involved the incorporation of research and implementation of evidence‐based practice to improve patient care. This article discusses the theory of planned behavior (TPB) and its possible application in the perioperative practice area. There is a lack of published literature on the direct use of the TPB to describe and explain perioperative practice behaviors. Perioperative leaders and educators can use this theory to help them understand their staff members' behaviors (eg, lack of adherence to policies for patient care activities [eg, surgical counting]). Using the model may help leaders and educators determine the intentions behind staff members' behaviors and identify participants' attitudes, subjective beliefs, and perceived control over their behaviors. This information should help leaders and educators implement effective strategies to improve patient safety and clinical outcomes. AN - 142060295. Language: English. Entry Date: 20200307. Revision Date: 20200307. Publication Type: Article. Journal Subset: Core Nursing AU - Rollon, Ronald DB - ccm DO - 10.1002/aorn.12959 DP - EBSCOhost IS - 3 KW - Perioperative Nursing Nursing Practice Ajzen's Theory of Planned Behavior Quality of Nursing Care Psychology, Social Health Beliefs Employee Attitudes Intention Surgical Count Procedure N1 - Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2020 SN - 0001-2092 SP - 327-331 ST - Using the Theory of Planned Behavior to Improve Perioperative Practice T2 - AORN Journal TI - Using the Theory of Planned Behavior to Improve Perioperative Practice UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=142060295&site=ehost-live&scope=site VL - 111 ID - 711 ER - TY - JOUR AN - 104056723. Language: English. Entry Date: 20140328. Revision Date: 20150818. Publication Type: Journal Article. Journal Subset: Core Nursing AU - Norton, Elizabeth DB - ccm DO - 10.1016/S0001-2092(14)00288-9 DP - EBSCOhost IS - 4 KW - Retained Instruments -- Prevention and Control Technology -- Utilization Surgical Count Procedure Bar Coding Surgical Sponges N1 - Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Patient Safety; Perioperative Care. NLM UID: 0372403. PMID: NLM24800309. PY - 2014 SN - 0001-2092 SP - C5-6 ST - Using technology to prevent retained sponges T2 - AORN Journal TI - Using technology to prevent retained sponges UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104056723&site=ehost-live&scope=site VL - 99 ID - 832 ER - TY - JOUR AB - Retained items (eg, sponges, sharps) after surgical procedures are reportable errors that can result in patient harm or death and increased patient and health care system costs. Perioperative use of radiofrequency (RF) technology may decrease the number of retained sponges and reduce hospital costs. We sought to determine whether the use of RF technology may be associated with fewer retained sponges, improved patient outcomes, and decreased hospital costs. We completed a retrospective evaluation of incident reports before and after implementing the use of an RF system for retained surgical sponges. We found that using RF technology was associated with fewer retained sponges and improved outcomes at our facility. We also determined that mortality rates before and after RF technology implementation were similar, and we estimated that our hospital's costs were reduced. AN - 32990961 AU - Primiano, M. AU - Sparks, D. AU - Murphy, J. AU - Glaser, K. AU - McNett, M. DA - Oct DO - 10.1002/aorn.13171 DP - NLM ET - 2020/09/30 IS - 4 KW - human error manual surgical count radiofrequency (RF) technology retained surgical item surgical sponge LA - eng N1 - 1878-0369 Primiano, Mike Sparks, Deb Murphy, Jill Glaser, Kathleen McNett, Molly Journal Article United States AORN J. 2020 Oct;112(4):345-352. doi: 10.1002/aorn.13171. PY - 2020 SN - 0001-2092 SP - 345-352 ST - Using Radiofrequency Technology to Prevent Retained Sponges and Improve Patient Outcomes T2 - Aorn j TI - Using Radiofrequency Technology to Prevent Retained Sponges and Improve Patient Outcomes VL - 112 ID - 262 ER - TY - JOUR AN - 105792574. Language: English. Entry Date: 20080822. Revision Date: 20150818. Publication Type: Journal Article AU - Frasher, P. AU - Maxwell-Downing, D. DB - ccm DP - EBSCOhost IS - 1 KW - Radio Frequency Identification Surgical Count Procedure -- Methods Surgical Equipment and Supplies N1 - commentary; letter; response. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PMID: NLM18603031. PY - 2008 SN - 0001-2092 SP - 19-20 ST - Using bar-code technology to assist with counting...Downing D. Counting sterile towels. (Clinical Issues). AORN J. 2008;87(4): 823-6 T2 - AORN Journal TI - Using bar-code technology to assist with counting...Downing D. Counting sterile towels. (Clinical Issues). AORN J. 2008;87(4): 823-6 UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105792574&site=ehost-live&scope=site VL - 88 ID - 852 ER - TY - JOUR AN - 104632568. Language: English. Entry Date: 20120224. Revision Date: 20150818. Publication Type: Journal Article. Journal Subset: Core Nursing DB - ccm DO - 10.1016/j.aorn.2011.10.023 DP - EBSCOhost IS - 1 KW - Adverse Health Care Event -- Prevention and Control Checklists -- Utilization Malpractice -- Prevention and Control Surgery, Operative Operating Room Personnel Postoperative Complications -- Prevention and Control Surgical Count Procedure N1 - Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 0372403. PY - 2012 SN - 0001-2092 SP - 168-169 ST - Using a surgical safety checklist to prevent malpractice claims T2 - AORN Journal TI - Using a surgical safety checklist to prevent malpractice claims UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104632568&site=ehost-live&scope=site VL - 95 ID - 835 ER - TY - JOUR AB - BACKGROUND: Retained surgical items (RSIs), most commonly sponges, are infrequent. Yet despite sponge-counting standards, failure to maintain an accurate count is a common error. To improve counting performance, technology solutions have been developed. A data-matrix-coded sponge (DMS) system was evaluated and implemented in a high-volume academic surgical practice at Mayo Clinic Rochester (MCR). The primary end point was prevention of sponge RSIs after 18 months. METHODS: Two trials were conducted before implementation. A randomized-controlled trial assessed the system's function, efficiency, and ergonomics. The second, larger trial was conducted to validate the prior findings and test product improvements. After the trials, the system was implemented in all 128 operating/procedure rooms across the MCR campus on February 2, 2009. The institutionwide implementation was intended to avoid the possibility of having standard unmarked sponges and DMSs in the operating room suite concurrently. RESULTS: Before implementation, a retained sponge occurred on average every 64 days. Between February 2009 and July 2010, 87,404 procedures were performed, and 1,862,373 DMSs were used without an RSI (p < .001). After four cases, the average time to count a DMS decreased from 11 to 4 seconds. Total sponge counting time/operation increased without any increase in overall operative time. CONCLUSIONS: After 18 months, a DMS system eliminated sponge RSIs from a high-volume surgical practice. The DMS system caused no work-flow disruption or increases in case duration. Staff satisfaction was acceptable, with a high degree of trust in the system. The DMS system is a reliable and cost-effective technology that improves patient safety. AD - Surgical Services, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA. Cima.Robert@Mayo.edu AN - 21939132 AU - Cima, R. R. AU - Kollengode, A. AU - Clark, J. AU - Pool, S. AU - Weisbrod, C. AU - Amstutz, G. J. AU - Deschamps, C. DA - Feb DO - 10.1016/s1553-7250(11)37007-9 DP - NLM ET - 2011/09/24 IS - 2 KW - Cost-Benefit Analysis Electronic Data Processing/*methods Foreign Bodies/*prevention & control Humans Medical Errors/*prevention & control Observer Variation Pilot Projects Quality Assurance, Health Care/methods Surgical Procedures, Operative/*methods *Surgical Sponges Time Factors LA - eng N1 - Cima, Robert R Kollengode, Anantha Clark, James Pool, Sarah Weisbrod, Cheryl Amstutz, Gwendolyn J Deschamps, Claude Journal Article Netherlands Jt Comm J Qual Patient Saf. 2011 Feb;37(2):51-8. doi: 10.1016/s1553-7250(11)37007-9. PY - 2011 SN - 1553-7250 (Print) 1553-7250 SP - 51-8 ST - Using a data-matrix-coded sponge counting system across a surgical practice: impact after 18 months T2 - Jt Comm J Qual Patient Saf TI - Using a data-matrix-coded sponge counting system across a surgical practice: impact after 18 months VL - 37 ID - 114 ER - TY - JOUR AB - URYX is a biocompatible polymer of ethylene vinyl alcohol dissolved in a dimethyl sulfoxide (DMSO) carrier to allow injection of a very low-viscosity fluid into tissue. Once the material comes into contact with body tissue or fluid, the DMSO rapidly dissipates from the polymer, which results in a precipitate of a coherent solid mass. The purpose of the present study was to determine whether URYX can effectively occlude the vas deferens and whether patency can be restored by redissolving the URYX in vivo using the solvent DMSO. Eight male New Zealand White rabbits (age range, 25-41 weeks; mean age, 33.9 ± 7.5 weeks; mean weight, 4.0 ± 0.2 kg) were used in 2 experiments (E1 and E2). In E1, 3 rabbits underwent unilateral vasectomy, and the contralateral vas was injected with either 0.05 or 0.10 mL of URYX, to determine the amount of URYX required to cause obstruction. Two animals underwent bilateral vasectomy, to serve as controls. In E2, 3 animals underwent bilateral URYX injection and were compared with the bilateral vasectomy control rabbits used in E1. After 1 month of initial bilateral URYX treatment, all animals in E2 underwent attempted unilateral reversal with 1.5 mL of DMSO injected into 1 occluded vas deferens. Two end points were evaluated-a clinical end point assessed by semen analyses and a pathological end point assessed by histological analysis of treated tissues, to assess for safety. A 1.5-cm infrapubic incision was made to expose both vasa in anesthetized rabbits. The vasal injection of URYX was performed with a 30-gauge needle. Vasectomy was performed by excision of a 1-cm segment of the vas deferens and subsequent ligation with a 6-0 prolene suture. Semen was collected using an artificial vagina 2-3 times/wk before and 1 month later, after injection treatments and vasectomy. Manual sperm counts were performed. All animals were sacrificed, and tissues (distal vas, injection site, proximal vas, cauda epididymis, caput epididymis, and testis) were harvested and examined for the presence of URYX. The inflammatory response of the wall and adventitia of the vas deferens was given a score (0-15) based on the sum of grades (0 = none, 1 = mild, 2 = moderate, and 3 = severe) for the following categories: foreign body giant cell reaction, granulation tissue, lymphocytes, eosinophils, and scarring, as evaluated by a single pathologist (J.M.). Vasal injection with 0.05 mL of URYX was not sufficient to cause occlusion. Both animals injected with 0.1 mL of URYX were effectively occluded. The injection of occluded vasa with DMSO did not dissolve the URYX plug in the vas lumen. There was no significant difference in vasal inflammatory response scores between vasal units treated with URYX only and vasal units in the vasectomy model. Vasal units subjected to URYX followed by DMSO demonstrated greater inflammatory response scores than vasal units treated with URYX followed by normal saline, URYX alone, or vasectomy. Epididymal and testicular histology remained unaffected in all vasal units in E1. The vasal units in E2 subjected to URYX followed by normal saline showed no histological abnormalities of the epididymis and testis. However, those vasal units subjected to URYX followed by DMSO in E2 showed evidence of adhesions, necrosis, and degenerating cells in the epididymis and a focal foreign body giant cell reaction in the testis. The bilateral vasal injection of URYX can result in azoospermia in the rabbit model. Reversal with subsequent DMSO injection was not achieved. A minimal inflammatory response of the vas deferens was observed with URYX injection alone; however, DMSO following URYX injection resulted in increased vasal inflammation, in addition to epididymal and testicular changes. AD - Division of Urological Surgery, Washington Univ. School of Medicine, St. Louis, MO, United States Department of Anatomic Pathology, Cleveland Clinic Foundation, Cleveland, OH, United States Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, OH, United States Division of Urologic Surgery, Washington Univ. School of Medicine, Infertility and Repro. Med. Center, 4444 Forest Park Avenue, St. Louis, MO 63108, United States Dept. of Male Infertility/Microsurg., Washington Univ. School of Medicine, Infertility and Repro. Med. Center, 4444 Forest Park Avenue, St. Louis, MO 63108, United States AU - Naughton, C. K. AU - Myles, J. AU - Thomas Jr, A. J. DB - Scopus DO - 10.1002/j.1939-4640.2004.tb02825.x IS - 4 KW - DMSO Epididymis Testicle Vas deferens M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2004 SP - 545-553 ST - The use of URYX for reversible vasectomy in a rabbit model T2 - Journal of Andrology TI - The use of URYX for reversible vasectomy in a rabbit model UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-3042777398&doi=10.1002%2fj.1939-4640.2004.tb02825.x&partnerID=40&md5=e221063c856cad2e9b06cecf2e62b28f VL - 25 ID - 1638 ER - TY - JOUR AB - Introduction: The National Audit Project 5, whilst demonstrating an overall low risk of accidental awareness under general anaesthesia (AAGA), highlighted an incidence of 1:670 in patients undergoing general anaesthesia (GA) for caesarean section (CS), more than any other surgical category. 1 There is a higher risk of difficult intubation (incidence 1:300) in the obstetric patient, and the recent Every Baby Counts report highlights the importance of induction preparation.2, 3 Our tertiary obstetric centre has recently recommended routine addition of a bolus of intravenous alfentanil as part of a modified rapid-sequence induction (RSI), aiming to reduce these complications. We conducted a multi-speciality service evaluation project to establish whether this modification in anaesthetic technique had any adverse neonatal effects, compared with traditional RSI technique. Methods: Data were collected retrospectively between July 2017 and April 2018. Maternal data were collected using electronic operative records and recorded alfentanil usage. Neonatal data were collected using electronic recording systems. All patients undergoing emergency CS under GA were included. RSI method included thiopental and suxamethonium with the potential addition of alfentanil 0.5-2 mg (mean dose 1 mg). Results: Ten neonates in the alfentanil group were premature as were eight in the non-alfentanil group; none were include in further analysis. Nine term babies required admission to the neonatal unit; five were exposed to alfentanil and four were not. Apgar scores at 1 and 5 min were significantly lower in the alfentanil group (P=0.02). In category 1 caesarean section term neonates, 14/18 (77%) babies exposed to alfentanil required resuscitative input. One neonate required CPR. There were no infant deaths. 16/28 (57%) babies not exposed to alfentanil required resuscitative measures. Discussion: Results suggest alfentanil was associated with lower Apgar scores and an increased requirement for additional brief medical intervention, particularly stimulation and inflation breaths at time of delivery but significantly, that this did not lead to additional unplanned neonatal admissions or harm. Furthermore, babies included in this project were already deemed to be at risk of requiring initial medical assistance, such is the nature of emergency operative delivery, and additional induction opioid does not seem to have increased this risk. We are therefore reassured that the addition of alfentanil is unlikely to worsen neonatal outcomes whilst potentially benefiting the mother. AU - Farrimond, R. E. AU - Roberts, F. AU - Wallis, R. AU - Brimfield, L. DB - Embase DO - 10.1016/j.ijoa.2019.02.006 KW - alfentanil opiate suxamethonium thiopental Apgar score awareness breathing cesarean section child death complication conference abstract drug therapy emergency female general anesthesia genetic susceptibility human incidence infant intubation major clinical study medical care newborn obstetric patient retrospective study LA - English M3 - Conference Abstract N1 - L2002296270 2019-07-19 PY - 2019 SN - 1532-3374 0959-289X SP - 40 ST - The use of alfentanil in a modified rapid sequence induction for general anaesthesia caesarean sections: is this doing any harm? T2 - International Journal of Obstetric Anesthesia TI - The use of alfentanil in a modified rapid sequence induction for general anaesthesia caesarean sections: is this doing any harm? UR - https://www.embase.com/search/results?subaction=viewrecord&id=L2002296270&from=export http://dx.doi.org/10.1016/j.ijoa.2019.02.006 VL - 39 ID - 309 ER - TY - JOUR AB - Background: This case report presents the treatment of a large infected skin defect, which was caused by an accidental explosion, through a skin-stretching device combined with vacuum sealing drainage. To the best of our knowledge, the area of the wound that we treated may currently be the largest. Case presentation: A 41-year-old Asian man was transferred to the Center of Trauma Surgery of our hospital for the closure of an open infected wound with a large skin defect in his right lower limb caused by an accidental explosion of 100 pieces of blasting cap. The wounds located in his right gluteal were approximately 40 cm × 35 cm. On admission, the wounds had hemorrhaged, exhibiting a darkened appearance, and included scattered metallic foreign bodies. Debridement of his right gluteal area was conducted 6 hours after injury. Subsequently, a skin-stretching device combined with vacuum sealing drainage was applied to reduce the skin defect. This treatment proved to be valuable for the closure of the skin defect and to attain successful functional rehabilitation without sciatic nerve entrapment or amputation in this case. Conclusions: It is difficult to close large skin defects, especially when they are infected. The application of a skin-stretching device combined with vacuum sealing drainage should be commonly applied to treat infected wounds because it is a safe and easy operative technique. © 2018 The Author(s). AD - Center of Trauma Surgery, Daping Hospital, Third Military Medical University, State Key Laboratory of Trauma, Burns and Combined Injury, Chongqing, 400042, China AU - Lei, Y. AU - Liu, L. AU - Du, S. H. AU - Zong, Z. W. AU - Zhang, L. Y. AU - Guo, Q. S. C7 - 264 DB - Scopus DO - 10.1186/s13256-018-1779-8 IS - 1 KW - Blast injury Skin defect Skin stretching Vacuum sealing drainage M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2018 ST - The use of a skin-stretching device combined with vacuum sealing drainage for closure of a large skin defect: A case report T2 - Journal of Medical Case Reports TI - The use of a skin-stretching device combined with vacuum sealing drainage for closure of a large skin defect: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85052745361&doi=10.1186%2fs13256-018-1779-8&partnerID=40&md5=6fce70a07d5a97b5acf3b7b8b37e7087 VL - 12 ID - 1059 ER - TY - JOUR AB - Objective: To know the diagnostic tools and proper management of ureterovaginal fistula following neglected vaginal foreign body in order to achieve optimal outcome. Case report: A case of ureterovaginal fistula associated with a neglected vaginal foreign body. The patient was complaining of a foul-smelling vaginal discharge and lower abdominal pain. On vaginal examination, a hard and large foreign body was found. Examination under anesthesia was performed, and an aerosol cap was removed from her vagina. The patient developed urinary incontinence after removal of the foreign body. Subsequent work-up demonstrated the presence of a right ureterovaginal fistula. The patient underwent an abdominal ureteroneocystostomy. At one year follow up, the patient had fully recovered. Conclusion: Ureterovaginal fistula following neglected vaginal foreign body is a serious condition. Early diagnosis, treatment of infection and proper surgical management can improve the outcome and decrease complications. © 2018 AD - Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Keelung Medical Center, Keelung, Taiwan Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taipei Medical Center, Taipei, Taiwan Division of Urogynecology, Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan Chang Gung University, School of Medicine, Taoyuan, Taiwan Department of Obstetrics and Gynecology, Hospital UmumSarawak, Malaysia Fellow of the Division of Urogynecology, Department of Obstetrics & Gynecology, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan Department of Obstetrics and Gynecology, Al-Bashir Hospital, Amman, Jordan Department of Obstetrics and Gynecology, Dr. Pablo O. Torre Memorial Hospital, Bacolod City, Philippines AU - Lo, T. S. AU - Jaili, S. B. AU - Ibrahim, R. AU - Kao, C. C. AU - Uy-Patrimonio, M. C. DB - Scopus DO - 10.1016/j.tjog.2017.12.026 IS - 1 KW - Ureteroneocystostomy Ureterovaginal fistula Vagina foreign body M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 SP - 150-152 ST - Ureterovaginal fistula: A complication of a vaginal foreign body T2 - Taiwanese Journal of Obstetrics and Gynecology TI - Ureterovaginal fistula: A complication of a vaginal foreign body UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85040240910&doi=10.1016%2fj.tjog.2017.12.026&partnerID=40&md5=6c3ba187d6b93d6ad26b0fa6f914f4e2 VL - 57 ID - 1090 ER - TY - JOUR AN - 108150307. Language: English. Entry Date: 20121005. Revision Date: 20150712. Publication Type: Journal Article AU - Martindell, Denise DB - ccm DP - EBSCOhost IS - 3 KW - Incident Reports -- Statistics and Numerical Data -- Pennsylvania Practice Guidelines Quality Improvement Retained Instruments -- Prevention and Control AORN Minimally Invasive Procedures Multidisciplinary Care Team Needles Pennsylvania Risk Management -- Methods Surgical Count Procedure Surgical Sponges N1 - case study. Journal Subset: Health Promotion/Education; USA. Special Interest: Patient Safety; Perioperative Care. PY - 2012 SN - 1941-7144 SP - 106-110 ST - Update on the Prevention of Retained Surgical Items T2 - Pennsylvania Patient Safety Advisory TI - Update on the Prevention of Retained Surgical Items UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108150307&site=ehost-live&scope=site VL - 9 ID - 826 ER - TY - JOUR AB - BACKGROUND: Wrong site surgery is one of five surgical "Never Events," which include performing surgery on the incorrect side or incorrect site, performing the wrong procedure, performing surgery on the wrong patient, unintended retention of a foreign object in a patient, and intraoperative/immediate postoperative death in an ASA Class I patient. In the spine, wrong site surgery occurs when a procedure is performed on an unintended vertebral level. Despite the efforts of national safety protocols, literature suggests that the risk for wrong level spine surgery remains problematic. CASE PRESENTATION: A 34-year-old male was referred to us to evaluate his persistent thoracic pain following right-sided microdiscectomy at T7-8 at an outside institution. Postoperative imaging showed the continued presence of a herniated disc at T7-8 and evidence of a microdiscectomy at the level immediately above. The possibility that wrong level surgery had occurred was discussed with the patient and revision surgery was planned. During surgery, the site of the previous laminectomy was clearly visualized; however, we also experienced confusion when verifying the level of the previous surgery. We ultimately used the previous laminectomy site as a landmark for identifying and treating the correct pathologic level. Postoperative consultation with Musculoskeletal Radiology revealed the patient had two abnormalities in his spinal anatomy that made intraoperative counting of levels inaccurate, including a pair of cervical ribs at C7 and the absence of a pair of thoracic ribs. CONCLUSION: This case highlights the importance of strict adherence to a preoperative method of vertebral labeling that focuses on the landmarks used to label a pathologic disc space, rather than simply relying on the reference to a particular level. That is, by designating the pathological level as the disc space associated with the fourth rib up from the last rib-bearing vertebrae, rather than calling it "T7-8", then the correct level can be found intraoperatively even in the case of abnormal segmentation. We recommend working closely with radiology during preoperative planning to identify unusual anatomy that may have been overlooked. We also recommend that radiology colleagues use the same system of identifying pathological levels when dictating their reports. Together, these strategies can reduce the risk of wrong level surgery and increase patient safety. AD - Department of Orthopaedics, University of Colorado Denver, Denver CO, USA. emily.lindley@ucdenver.edu. AN - 22168745 AU - Lindley, E. M. AU - Botolin, S. AU - Burger, E. L. AU - Patel, V. V. C2 - PMC3259034 DA - Dec 14 DO - 10.1186/1754-9493-5-33 DP - NLM ET - 2011/12/16 IS - 1 LA - eng N1 - 1754-9493 Lindley, Emily M Botolin, Sergiu Burger, Evalina L Patel, Vikas V Journal Article Patient Saf Surg. 2011 Dec 14;5(1):33. doi: 10.1186/1754-9493-5-33. PY - 2011 SN - 1754-9493 SP - 33 ST - Unusual spine anatomy contributing to wrong level spine surgery: a case report and recommendations for decreasing the risk of preventable 'never events' T2 - Patient Saf Surg TI - Unusual spine anatomy contributing to wrong level spine surgery: a case report and recommendations for decreasing the risk of preventable 'never events' VL - 5 ID - 119 ER - TY - JOUR AB - Tracheobronchial foreign body aspiration is one of the most life-threatening diseases in children. Its symptom is non-specific sometimes; therefore the distinction with some similar clinical presentation pulmonary disease should be performed. Here, we reported a 5-year-old girl who was misdiagnosed with foreign body aspiration twice based on the broncho-obstructive symptom and radiologic finding. Finally, the diagnosis of broncholithiasis was confirmed by finding broncholiths in the respiratory tract through bronchoscopy. It is replied that bronchoscopy should be performed in the children with unexplained airway obstruction symptom. Furthermore, it is the first report about the broncholiths located at the upper main trachea. © 2016 Elsevier Ltd AD - Department of Otolaryngology, Guangzhou Women and Children's Medical Center, Guangzhou, 510120, China AU - Feng, S. AU - Liu, D. AU - Huang, Z. AU - Zhong, J. AU - Zhong, J. DB - Scopus DO - 10.1016/j.pedex.2016.05.001 KW - Broncholithiasis Bronchoscopy Foreign body M3 - Article N1 - Export Date: 10 November 2020 PY - 2016 SP - 50-52 ST - An unusual respiratory tract foreign body: A case report of pediatric broncholithiasis T2 - International Journal of Pediatric Otorhinolaryngology Extra TI - An unusual respiratory tract foreign body: A case report of pediatric broncholithiasis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85000956224&doi=10.1016%2fj.pedex.2016.05.001&partnerID=40&md5=bd0eb1306c9d7a83a2ec2183d8d59d1d VL - 13 ID - 1170 ER - TY - JOUR AB - Background: Unintentional acid ingestion is less commonly encountered than alkali ingestion. The injury develops for hours to days after ingestion and often results in progressively increasing difficulty in airway management. However, gastric perforation is rare. Case: A 3-year-old boy presented to us with an orotonsillopharyngeal membrane and severe upper airway obstruction. Subsequently, he was diagnosed with a case of gastric perforation due to unintentional hydrochloric acid ingestion. He was treated with partial gastrectomy and feeding jejunostomy, and the recovery was good. Conclusions: Unintentional hydrochloric acid ingestion is rare in children. The manifestations masquerade many other clinical conditions, and the diagnosis is difficult in cases in which history of ingestion is not available. Treatment is symptomatic, and emergency surgery is indicated in case of gastrointestinal perforation. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved. AD - G Kuppuswamy Naidu Memorial Hospital, Coimbatore, India Department of Pediatrics, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, India Global Hospitals 439, Perumbakkam, Chennai, 600100, India Department of Pediatrics, All India Institute of Medical Sciences (AIIMS), New Delhi, India AU - Ganapathy, V. P. AU - Das, R. R. AU - Chinnakkannan, S. AU - Panda, S. S. DB - Scopus DO - 10.1097/PEC.0000000000000382 IS - 3 KW - Gastric perforation Hydrochloric acid Tonsillopharyngitis White membrane M3 - Article N1 - Export Date: 10 November 2020 PY - 2015 SP - 207-208 ST - An unusual presentation of hydrochloric acid ingestion: A mystery unraveled T2 - Pediatric Emergency Care TI - An unusual presentation of hydrochloric acid ingestion: A mystery unraveled UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84924854703&doi=10.1097%2fPEC.0000000000000382&partnerID=40&md5=6732aaaca73ab2d2f3245c3dbc797dec VL - 31 ID - 1230 ER - TY - JOUR AB - Objective: Background: Case Report: Conclusions: Rare disease Indigestible foreign material in the bowel can develop into bezoars. Intestinal obstruction can occur secondary to these bezoars. Phytobezoars specifically refer to those which accumulate as a result of undigested plant or other food material. A 42-year-old woman presented to the Emergency Department with a several-month history of right-sided abdominal pain associated with bouts of vomiting. She had no other significant medical history. Labs and computed tomography were unrevealing. Gastroenterology was consulted and performed endoscopy. A foreign body resembling an undigested mini bell pepper was found near the terminal ileum. This was removed, and the patient later reported significant improvement in her symptoms. Phytobezoars can lead to symptoms consistent with intestinal obstruction. The underlying pathology (e.g., masses, gastritis, adhesions, or dysmotility) can precipitate obstructions in the setting of bezoar formation. Surgical removal if often necessary for small-bowel obstructions secondary to bezoars, but in our case, fortunately, the foreign body was successfully removed during endoscopy. © 2019, International Scientific Information, Inc. All rights reserved. AD - Department of Emergency Medicine, Mayo Clinic, Jacksonville, FL, United States AU - Mohseni, M. AU - Kruse, B. DB - Scopus DO - 10.12659/AJCR.920621 KW - Bezoars Endoscopy Gastroenterology Intestinal Pseudo-Obstruction M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 1920-1922 ST - An unusual mimic of intermittent bowel obstruction T2 - American Journal of Case Reports TI - An unusual mimic of intermittent bowel obstruction UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85077148606&doi=10.12659%2fAJCR.920621&partnerID=40&md5=f803f880f234be1561737730e6af5209 VL - 20 ID - 1037 ER - TY - JOUR AB - Introduction. There are several causes of peri-implant edema, pain, and swelling around implants after orthopedic fixation device application for fracture repair. The most common and well-known reason is infection, however, granulomas associated with foreign body reactions are rarely seen. In this report we present a case of a granulomatous reaction mimicking a hydatid cyst and sarcoma. We emphasize the importance of differential diagnosis in triggering appropriate management of the patient. Our case was unusual; to the best of our knowledge no similar clinical or pathological findings have been reported in current literature. Case presentation. A 56-year-old Turkish man who had been treated for a right femoral fracture via a plate fixation 10 years prior underwent an operation to treat pain and swelling around the plate. A hydatid cyst-like mass was observed during surgery, but subsequent examination revealed that no hydatid cyst was present; both malignancy and infection were also absent. Conclusions: Although infection is generally the first possibility that should be considered in a patient complaining of pain and swelling in the vicinity of an implant, malignancies, hydatid cysts, and (finally) foreign body reactions should also be kept in mind as differential diagnoses. A soft-tissue reaction around a previously implanted plate should be managed carefully. Pre-operative radiological assessment, and biopsy to allow pathological and microbiological examination, should be considered in all suspected cases. © 2014 Ozkanli et al.; licensee BioMed Central Ltd. AD - Department of Pathology, Göztepe Training and Research Hospital, Fahrettin Kerim Gökay Street, 2346 Istanbul, Turkey Department of Orthopedics and Traumatology, Göztepe Training and Research Hospital, Fahrettin Kerim Gökay Street, 2346 Istanbul, Turkey Department of Orthopedics and Traumatology, School of Medicine, Bezmialem Vakif University, Vatan Street, 34080 Istanbul, Turkey Göztepe E.A.H., Fahrettin Kerim Gökay Street, 2346 Kadiköy/Istanbul, Turkey AU - Ozkanli, S. AU - Soylemez, M. S. AU - Sahin, A. AU - Senol, S. AU - Bilsel, K. AU - Ceylan, H. H. C7 - 187 DB - Scopus DO - 10.1186/1752-1947-8-187 IS - 1 KW - Granuloma Malignancy Orthopedic hardware Soft-tissue reaction M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2014 ST - Unusual implant-related soft tissue reaction presenting as a swollen leg: A case report T2 - Journal of Medical Case Reports TI - Unusual implant-related soft tissue reaction presenting as a swollen leg: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84902064747&doi=10.1186%2f1752-1947-8-187&partnerID=40&md5=71fa421ab60d6016fcb39a3c60b8163f VL - 8 ID - 1259 ER - TY - JOUR AB - Rare earth metal magnets (Buckyballs and similar products) remain an important public health risk for children.We report the presentation, course, and treatment of a boy who inserted a string of 30 magnets through his urethra into his bladder and review the diagnostic as well as the therapeutic options for foreign bodies inserted into the pediatric urogenital tract.. Copyright © 2014 by Lippincott Williams &Wilkins. AD - Departments of Emergency Medicine, Emergency Medicine, Yale University, 100 York St, 1, New Haven, CT 06511, United States Departments of Urology, United States Departments of Pediatrics, Yale University, New Haven, CT, United States AU - Robey, T. E. AU - Kaimakliotis, H. Z. AU - Hittelman, A. B. AU - Walsh, S. A. DB - Scopus DO - 10.1097/PEC.0000000000000214 IS - 9 KW - adolescent foreign bodies magnets M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2014 SP - 643-645 ST - An unusual destination for magnetic foreign bodies T2 - Pediatric Emergency Care TI - An unusual destination for magnetic foreign bodies UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84964199503&doi=10.1097%2fPEC.0000000000000214&partnerID=40&md5=74568ff2d98f7b3e1c64ae9a857e59e9 VL - 30 ID - 1266 ER - TY - JOUR AB - A man aged 22 was awakened by sharp, stabbing pains in the left eye, whereupon he discovered a 5 in. long scorpion lying across the eye and temporal area. The arachnid was brushed off and destroyed. The eye became red and throbbed with continuous pain. The eyelids swelled and vision was blurred within 1 hour; lacrimation and photophobia were marked. Emergency treatment consisted of 50 mg. of diphenhydramine hydrochloride, orally q.i.d., warm compresses every 2 hours, and the instillation of penicillin ophthalmic ointment in the conjunctival sac. Examination 3 days later by an ophthalmologist showed vision to be decreased to finger count at 3 feet, ciliary injection, punctate keratitis, and iritis. Slit-lamp microscopy revealed mild oedema of the entire cornea. A needle-like shaft about 3 mm. long was embedded horizontally deep in the substantia propria of the cornea. A slight reaction was noted about this shaft. No staining with fluorescein. Several minute punctate lesions were seen on the epithelial surface of the cornea. There was a slight flare in the anterior chamber but no cells were noted. The iris, vitreous, and fundus were normal. The foreign body was invisible to the naked eye. Under 0.5% pontocaine topical anaesthesia the foreign body was extracted using a small Graefe knife and forceps with the aid of slit-lamp visualization. Because of its friability it was removed in 4 separate pieces. The base was cleaned with a small dental burr. The eye was dressed with an ointment containing 0.1% aureomycin and 1% atropine. Cortisone solution (1:4 dilution) was instilled into the eye every 2 hours. The anti-histaminics were continued. The cornea was completely healed without scarring and the iritis had resolved within 6 days. Microscopic examination of the foreign body revealed a minute, tapering, thin shaft without segmentation. This was assumed to be the tail-tip of the scorpion. AD - W.R. True, U.S.S., Haven, United States AU - True, W. R. DB - Embase Classic Medline IS - 11 KW - atropine chlortetracycline cortisone diphenhydramine eye ointment fluorescein penicillin G tetracaine aged anesthesia anterior eye chamber arachnid cornea dilution drill edema emergency treatment examination eye eyelid forceps foreign body human injection injury iris iritis lacrimation microscopy needle ointment pain photophobia punctate keratitis recumbency scar formation scorpion slit lamp staining tail vitreous body LA - English M3 - Article N1 - L280622798 1951-12-01 PY - 1951 SN - 0566-0777 SP - 1741-1742 ST - Unusual corneal foreign body T2 - United States Armed Forces medical journal TI - Unusual corneal foreign body UR - https://www.embase.com/search/results?subaction=viewrecord&id=L280622798&from=export VL - 2 ID - 695 ER - TY - JOUR AB - Laparoscopic adjustable gastric banding (LAGB) is an often performed bariatric procedure for morbid obesity. Several complications are known, including surgery and port-side-associated complications. As rare but serious late complication of LAGB, we describe a 50-year-old patient with periodic incomplete intestinal constriction due to the silicone connecting tube, 4 years after laparoscopic adjustable gastric banding was performed. Abdominal CT scan showed an obstructive ileus due to a loop in the connecting tube. After surgical removal of the connecting tube, the patient recovered without sequelae. © 2009 Springer Science + Business Media, LLC. AD - Department of Surgery, Rijnland Hospital Leiderdorp, Simon Smitweg 1, Leiderdorp, GA 2353, Netherlands Department of Gerontology and Geriatrics, Leiden University Medical Centre, Leiden, Netherlands AU - Van De Water, W. AU - Vogelaar, F. J. AU - Willems, J. M. DB - Scopus DO - 10.1007/s11695-009-0057-7 IS - 1 KW - Bariatric surgery Jejunal obstruction Morbid obesity Postoperative complication M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2011 SP - 131-133 ST - An unusual complication 4 years after laparoscopic adjustable banding: Jejunal obstruction due to the connecting tube T2 - Obesity Surgery TI - An unusual complication 4 years after laparoscopic adjustable banding: Jejunal obstruction due to the connecting tube UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-78651247125&doi=10.1007%2fs11695-009-0057-7&partnerID=40&md5=7e387d167f4d3c932338487bb2408405 VL - 21 ID - 1437 ER - TY - JOUR AB - BACKGROUND: The term "gossypiboma" denotes a mass of cotton that is retained in the body following surgery. Gossypiboma is a medico-legal problem especially for surgeons. To the best of our knowledge, the patient presented herein is the second reported patient in whom the exact site of migration of a retained surgical textile material into the intestinal lumen could be demonstrated by preoperative imaging studies. CASE PRESENTATION: A 74-year-old woman presented with symptoms of small bowel obstruction due to incomplete intraluminal migration of a laparotomy towel 3 years after open cholecystectomy and umbilical hernia repair. Plain abdominal radiography did not show any sign of a radio-opaque marker in the abdomen. However, contrast enhanced abdominal computerized tomography revealed a round, well-defined soft-tissue mass with a dense, enhanced wall, containing an internal high-density area with air-bubbles in the mid-abdomen. A fistula between the abscess cavity containing the suspicious mass and gastrointestinal tract was identified by upper gastrointestinal series. The presence of a foreign body was considered. It was surgically removed with a partial small bowel resection followed by anastomosis. CONCLUSIONS: Although gossypiboma is rarely seen in daily clinical practice, it should be considered in the differential diagnosis of acute mechanical intestinal obstruction in patients who underwent laparotomy previously. The best approach in the prevention of this condition can be achieved by meticulous count of surgical materials in addition to thorough exploration of surgical site at the conclusion of operations and also by routine use of surgical textile materials impregnated with a radio-opaque marker. AD - Department of Gastrointestinal Surgery, Marmara University Institute of Gastroenterology, Istanbul, Turkey. rgencosmanoglu@marmara.edu.tr AN - 12962549 AU - Gencosmanoglu, R. AU - Inceoglu, R. C2 - PMC201033 DA - Sep 8 DO - 10.1186/1471-2482-3-6 DP - NLM ET - 2003/09/10 KW - Aged Diagnosis, Differential Female Foreign-Body Migration/*diagnostic imaging/surgery Humans Intestinal Obstruction/diagnostic imaging/*etiology/surgery Laparotomy Radiography *Surgical Sponges LA - eng N1 - 1471-2482 Gencosmanoglu, Rasim Inceoglu, Resit Case Reports Journal Article BMC Surg. 2003 Sep 8;3:6. doi: 10.1186/1471-2482-3-6. PY - 2003 SN - 1471-2482 SP - 6 ST - An unusual cause of small bowel obstruction: gossypiboma--case report T2 - BMC Surg TI - An unusual cause of small bowel obstruction: gossypiboma--case report VL - 3 ID - 44 ER - TY - JOUR AB - Background: The term "gossypiboma" denotes a mass of cotton that is retained in the body following surgery. Gossypiboma is a medico-legal problem especially for surgeons. To the best of our knowledge, the patient presented herein is the second reported patient in whom the exact site of migration of a retained surgical textile material into the intestinal lumen could be demonstrated by preoperative imaging studies. Case presentation: A 74-year-old woman presented with symptoms of small bowel obstruction due to incomplete intraluminal migration of a laparotomy towel 3 years after open cholecystectomy and umbilical hernia repair. Plain abdominal radiography did not show any sign of a radio-opaque marker in the abdomen. However, contrast enhanced abdominal computerized tomography revealed a round, well-defined soft-tissue mass with a dense, enhanced wall, containing an internal high-density area with air-bubbles in the mid-abdomen. A fistula between the abscess cavity containing the suspicious mass and gastrointestinal tract was identified by upper gastrointestinal series. The presence of a foreign body was considered. It was surgically removed with a partial small bowel resection followed by anastomosis. Conclusions: Although gossypiboma is rarely seen in daily clinical practice, it should be considered in the differential diagnosis of acute mechanical intestinal obstruction in patients who underwent laparotomy previously. The best approach in the prevention of this condition can be achieved by meticulous count of surgical materials in addition to thorough exploration of surgical site at the conclusion of operations and also by routine use of surgical textile materials impregnated with a radio-opaque marker. AD - R. Gencosmanoglu, Dept. of Gastrointestinal Surgery, Marmara Univ. Inst. Gastroenterol., Istanbul, Turkey AU - Gencosmanoglu, R. AU - Inceoglu, R. DB - Embase Medline DO - 10.1186/1471-2482-3-6 KW - abdominal radiography aged article case report cholecystectomy computer assisted tomography digestive system fistula end to end anastomosis female foreign body gossypiboma hernioplasty human laparotomy small intestine obstruction small intestine resection textile umbilical hernia LA - English M3 - Article N1 - L38803287 2004-07-01 PY - 2003 SN - 1471-2482 SP - 1-6 ST - An unusual cause of small bowel obstruction: Gossypiboma - Case report T2 - BMC Surgery TI - An unusual cause of small bowel obstruction: Gossypiboma - Case report UR - https://www.embase.com/search/results?subaction=viewrecord&id=L38803287&from=export http://dx.doi.org/10.1186/1471-2482-3-6 VL - 3 ID - 640 ER - TY - JOUR AD - Department of Surgery, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115, United States AU - Pernar, L. I. M. AU - Mongiu, A. AU - Sheu, E. G. DB - Scopus DO - 10.1001/jamasurg.2016.4614 IS - 2 M3 - Review N1 - Export Date: 10 November 2020 PY - 2017 SP - 199-200 ST - An unusual cause of intestinal perforation T2 - JAMA Surgery TI - An unusual cause of intestinal perforation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85014741716&doi=10.1001%2fjamasurg.2016.4614&partnerID=40&md5=b3b7b4313e410430e4f0c0f53b27aa12 VL - 152 ID - 1145 ER - TY - JOUR AB - Children have a natural tendency to explore objects with their mouths; this can result in the swallowing of foreign objects. Most ingested foreign bodies pass uneventfully through the gastrointestinal tract. However, some foreign bodies cause obstruction or perforation of the gastrointestinal tract, requiring surgical intervention. Perforation of the gastrointestinal tract may be associated with considerable morbidity and mortality. The most common sites of intestinal foreign body perforation are the ileocecal and rectosigmoid regions. Foreign body perforation of the duodenum is relatively uncommon. We report the first Korean case of duodenal perforation by an ingested 8-cm lollipop stick. Lollipops are popular with the children and fairly accessible to them, as most parents are not aware of their potential harm. Pediatric clinicians should be aware of the risks associated with lollipop-stick ingestion. Our report also describes the feasibility and safety of laparoscopic diagnosis and management of pediatric patients with peritonitis induced by the ingestion of foreign bodies. © 2013 by The Korean Pediatric Society. AD - Department of Pediatrics, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, South Korea Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea AU - Kim, M. J. AU - Seo, J. M. AU - Lee, Y. AU - Lee, Y. M. AU - Choe, Y. H. DB - Scopus DO - 10.3345/kjp.2013.56.4.182 IS - 4 KW - Duodenal perforation Foreign bodies Laparoscopy Lollipop stick M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2013 SP - 182-185 ST - An unusual cause of duodenal perforation due to a lollipop stick T2 - Korean Journal of Pediatrics TI - An unusual cause of duodenal perforation due to a lollipop stick UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84876484340&doi=10.3345%2fkjp.2013.56.4.182&partnerID=40&md5=61528eff1c2409fe69e1caa789905086 VL - 56 ID - 1335 ER - TY - JOUR AB - Foreign body ingestion occurs most commonly in the pediatric population. Small bowel obstruction is a rare complication that can occur, and surgical intervention is required. We present the first report of a case of an 18-month-old child with a jejunal obstruction caused by ingestion of water-storing gel beads used for botanical arrangements. The child presented with obstipation and nonbloody, nonbilious emesis. Symptoms resolved after a large bead 3 cm in diameter was retrieved via laparoscopic-assisted excision. This case suggests that water-storing gel beads are particularly dangerous foreign bodies and should be kept out of the reach of children. © 2012 Elsevier Inc. All rights reserved. AD - University of Southern California, Keck School of Medicine, Health Sciences Campus, Los Angeles, CA 90089, United States Department of Pediatric Surgery, Children's Hospital Los Angeles, Los Angeles, CA 90027, United States AU - Moon, J. S. AU - Bliss, D. AU - Hunter, C. J. DB - Scopus DO - 10.1016/j.jpedsurg.2012.04.005 IS - 9 KW - Foreign body Intestine obstruction Pediatric M3 - Article N1 - Cited By :11 Export Date: 10 November 2020 PY - 2012 SP - E19-E22 ST - An unusual case of small bowel obstruction in a child caused by ingestion of water-storing gel beads T2 - Journal of Pediatric Surgery TI - An unusual case of small bowel obstruction in a child caused by ingestion of water-storing gel beads UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84866246506&doi=10.1016%2fj.jpedsurg.2012.04.005&partnerID=40&md5=099a58a5a3e176eb7c3580333993589c VL - 47 ID - 1359 ER - TY - JOUR AB - PURPOSE: To report an extremely rare case involving a 41-year-old man with nine intraocular cilia embedded in the retina after a perforating ocular injury caused by a metal wire. This case is particularly rare because of the number and location of the cilia. OBSERVATIONS: The patient underwent an uneventful corneal suturing and extracapsular extraction of the damaged lens of his right eye. Intraocular foreign bodies were discovered following surgery and were removed at a later date. Following lens extraction and ocular repair, the patient's best-corrected visual acuity (BCVA) was counting fingers. Fundus examination during follow-up revealed several eyelashes embedded in the retina. Thirty-two days after the injury, the patient showed signs of ocular inflammation. Therefore, the patient underwent vitrectomy and intraocular foreign body removal. Nine cilia were embedded in the retina at the posterior perforation site. At the final follow-up visit, his BCVA was 20/25. CONCLUSION AND IMPORTANCE: This report describes an unusual case where intraocular cilia were embedded in the retina after a perforating ocular injury. The eyelashes caused an intraocular inflammatory reaction that subsided after their removal. AD - Department of Retina and Vitreous, Sorocaba Eye Hospital, Sorocaba, Sao Paulo, Brazil. Department of Anterior Segment, Sorocaba Eye Hospital, Sorocaba, Sao Paulo, Brazil. AN - 31993531 AU - Ramos, G. Z. AU - Goncalves, T. B. AU - Bordon, A. F. C2 - PMC6976869 DA - Mar DO - 10.1016/j.ajoc.2020.100587 DP - NLM ET - 2020/01/30 KW - Cilia Ocular foreign body Retina Vitrectomy LA - eng N1 - 2451-9936 Ramos, Gabriel Z Goncalves, Thiago B Bordon, Arnaldo F Case Reports Am J Ophthalmol Case Rep. 2020 Jan 7;17:100587. doi: 10.1016/j.ajoc.2020.100587. eCollection 2020 Mar. PY - 2020 SN - 2451-9936 SP - 100587 ST - An unusual case of nine cilia embedded in the retina after a perforating ocular injury T2 - Am J Ophthalmol Case Rep TI - An unusual case of nine cilia embedded in the retina after a perforating ocular injury VL - 17 ID - 240 ER - TY - JOUR AB - Purpose: Patency capsules are used commonly to test the patency of small bowel prior to performing a capsule enteroscopy. Although these capsules designed to dissolve in the intestine, we encountered a case of intestinal obstruction at the site of ileostomy after ingestion of a patency capsule. A 58-year-old Caucasian woman presented to the emergency room with abdominal pain in the right lower quadrant, around the ileostomy site for 12 hours. It was associated with marked decrease in ileostomy output. She had undergone total colectomy with ileostomy for ulcerative colitis 15 years ago. Recently, she was also diagnosed with iron deficiency anemia for which she had an upper endoscopy, which did not reveal any abnormality. A capsule enteroscopy was scheduled; however, prior to the procedure, it was noticed that the ileostomy opening was small and stenotic. Consequently, a patency capsule was administered to determine the ability of enteroscopy capsule to traverse the small intestine, on the day of presentation. On admission, her examination was remarkable for tenderness around the stoma and diminished bowel sounds. Laboratory evaluation was significant for microcytic hypochromic anemia (Hemoglobin 8.2 g/dL) and leukocytosis (WBC count 12.18 x 103/ml, 90% neutrophils). An upright abdominal X-ray showed a rectangular density (2.3 x 1.3 cm) in the right lower quadrant. CT scan of the abdomen showed the rectangular foreign body to be located in the ileostomy with proximal dilatation and multiple air fluid levels in the small bowel. An ileoscopy was performed which demonstrated an ileal stricture at 3 cms from the stoma. The stricture was dilated with a 12-15 mm CRE balloon. The intact patency capsule was located proximal to the stricture and it was retrieved with a Rothnet. After the procedure, patient's symptoms improved remarkably and she was discharged home with recommendation of push enteroscopy for work up of anemia. Patency capsules are made of lactose impregnated with barium and are designed to start dissolving 40 hours after oral ingestion. The dissolution is supposed to be complete by 80 hours, however, it may remain intact in patients with lactase deficiency. Similarly, in patients with severe stricture the patency capsule may not dissolve due to lack of contact with intestinal lactase. In the literature, there are 5 reported cases of patency capsule induced small bowel obstruction requiring surgery and all of the patients had underlying Crohn's disease or small bowel stricture. Therefore, it appears even patency capsules should be used with great caution in patients with small bowel stricture. Patients should be made aware of the potential complication prior to patency capsule administration. AD - S. Garg, Johns Hopkins Univeristy-Sinai Program in Internal Medicine, Baltimore, MD, United States AU - Garg, S. AU - Kaur, S. AU - Dutta, S. DB - Embase DO - 10.1038/ajg.2013.267 KW - lactose barium hemoglobin lactase intestine endoscopy college gastroenterology intestine obstruction human ileostomy patient small intestine capsule endoscopy iron deficiency anemia stoma ingestion procedures female examination Caucasian endoscopy ulcerative colitis computer assisted tomography liquid push enteroscopy lactase deficiency density neutrophil total colon resection emergency ward abdominal radiography leukocytosis intestine abdomen foreign body dilatation small intestine obstruction leukocyte count abdominal pain anemia dissolution laboratory intestine sound surgery Crohn disease LA - English M3 - Conference Abstract N1 - L71221269 2013-11-15 PY - 2013 SN - 0002-9270 SP - S290 ST - Unusual case of intestinal obstruction by patency capsule for enteroscopy T2 - American Journal of Gastroenterology TI - Unusual case of intestinal obstruction by patency capsule for enteroscopy UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71221269&from=export http://dx.doi.org/10.1038/ajg.2013.267 VL - 108 ID - 473 ER - TY - JOUR AB - A 45-year-old diabetic renal transplant recipient attended the transplant dermatology clinic with an 8-week history of an enlarging lesion on her left great toe. She had phototype VI skin, and had been immunosuppressed with tacrolimus 4- 5 mg twice daily and prednisolone 5 mg daily since her renal transplant in October 2011. Four months prior to presentation she underwent a laparotomy for Escherichia coli salpingitis with abscess formation, necessitating treatment with meropenem and discontinuation of mycophenolate mofetil. On examination, she had a solitary, tender 3.5 9 3-cm violaceous and slightly eroded nodule on the dorsal aspect of her left great toe. Full skin examination revealed no other lesions and no lymphadenopathy. Wound swabs grew normal skin flora, white-cell count and C-reactive protein were normal and HIV testing was negative. An incisional biopsy showed a fibrotic dermis and loose granulomatous inflammation with a foreign body giant cell reaction. The giant cells contained pigmented fungal elements and hyphae; periodic acid-Schiff and Grocott staining further highlighted fungi. Ziehl-Neelsen and Wade Fite were negative for acid fast bacilli and Gram staining was negative. The features were consistent with a deep fungal infection with black fungus or phaeohyphomycosis. Culture of the fungi then grew Exophiala jeanselmei. The patient was reviewed by the renal team and her tacrolimus dose was reduced gradually to 2 mg twice daily and she was commenced on voriconazole 200 mg twice daily. At review, 5 weeks into treatment, the lesion had reduced in size, and no new lesions or lymphadenopathy had developed. In conjunction with the renal and microbiology teams, we plan to continue voriconazole for 6 months and hope to avoid surgical intervention. E. jeanselmei is a dematiaceous fungus seen widely in plants, soil, water and decaying wood. Despite being a natural saprophyte, it is pathogenic in humans and the Exophiala species are part of a family of infectious fungi termed phaeohyphomycosis. These can produce subcutaneous infections such as mycetoma and chromoblastomycosis. Such infections are usually acquired via traumatic inoculation and are often associated with immunosuppression. As well as infection in subcutaneous tissues, prosthetic valvular vegetations, fungaemia and disseminated infections due to Exophiala spp. have been reported. While there is no standard treatment, combination surgical and antifungal treatment is usually required. Amphotericin B, flucytosine, itraconazole and terbinafine have been used. Prompt diagnosis of this rare opportunistic fungal infection ensures treatment can commence prior to systemic dissemination. A multi disciplinary approach with renal, microbiology, mycology, histology and dermatology input is essential for the successful management of such cases. AD - J. Fleming, St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom AU - Fleming, J. AU - Howell, S. AU - Robson, A. AU - Calonje, E. AU - Pattison, J. AU - Attard, N. AU - Wain, M. DB - Embase DO - 10.1111/bjd.12358 KW - tacrolimus voriconazole prednisolone C reactive protein flucytosine periodic acid mycophenolate mofetil soil water meropenem antifungal agent amphotericin B itraconazole terbinafine kidney graft graft recipient dermatologist human fungus infection Exophiala microbiology phaeohyphomycosis mycosis giant cell lymphadenopathy hallux dermatology salpingitis acid fast bacterium abscess dermis transplantation diabetes mellitus leukocyte count Escherichia coli fungemia HIV test biopsy granulomatous inflammation diagnosis fungus hyphae staining mycetoma skin flora Gram staining skin wound patient saprotroph laparotomy skin examination plant examination surgery hope species chromomycosis inoculation immunosuppressive treatment subcutaneous tissue vegetation hospital mycology histology Human immunodeficiency virus LA - English M3 - Conference Abstract N1 - L71125535 2013-08-07 PY - 2013 SN - 0007-0963 SP - 107 ST - An unusual black nodule in a renal transplant recipient T2 - British Journal of Dermatology TI - An unusual black nodule in a renal transplant recipient UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71125535&from=export http://dx.doi.org/10.1111/bjd.12358 VL - 169 ID - 480 ER - TY - JOUR AB - The causes of intra-abdominal masses associated with chronic abdominal pain range from the benign to malignant; common to bizarre and some raise major medical-legal issues. We present a case of a 40-year old African lady who presented with chronic right-sided abdominal pain with an associated mass on the right mid-abdomen. She had had a Caesarian section one year prior to presentation. Antecedent history of surgery and typical imaging features enabled a preoperative diagnosis of abdominal mass secondary to retained surgical gauze. The case illustrates the fallibility of the men and women in the operating theatres and the vital role of correct instrument and sponge counts. AD - Department of Surgery, Aga Khan Hospital, Nairobi, Kenya. AN - 17598670 AU - Saidi, H. AU - Mohammed, U. AU - Machoki, M. DA - Feb DO - 10.4314/eamj.v84i2.9509 DP - NLM ET - 2007/06/30 IS - 2 KW - Abdominal Neoplasms/*diagnosis/etiology Abdominal Pain/*diagnosis/pathology Adult Cesarean Section/adverse effects Chronic Disease Female Foreign Bodies/complications/*surgery Humans Laparotomy Surgical Sponges/*adverse effects LA - eng N1 - Saidi, H Mohammed, U Machoki, M Case Reports Journal Article Kenya East Afr Med J. 2007 Feb;84(2):88-92. doi: 10.4314/eamj.v84i2.9509. PY - 2007 SN - 0012-835X (Print) 0012-835x SP - 88-92 ST - An unusual abdominal mass: case report T2 - East Afr Med J TI - An unusual abdominal mass: case report VL - 84 ID - 66 ER - TY - JOUR AB - OBJECTIVE: this study aims to explore the experience of Brazilian surgeons on Unintentionally Retained Foreign Bodies (RFB) after surgical procedures. METHODS: A questionnaire was sent to surgeons by electronic mail, between March and July 2012. The questions analyzed their experience with foreign bodies (FB), foreign bodies' types, clinical manifestations, diagnoses, risk factors and legal implications. RESULTS: in the 2872 eligible questionnaires, 43% of the surgeons asserted that they had already left FB and 73% had removed FB in one or more occasions, totalizing 4547. Of these foreign bodies, 90% were textiles, 78% were discovered in the first year and 14% remained asymptomatic. Among doctors with less than five years after graduation, 36% had already left a FB. The most frequently surgical procedures mentioned were the elective (57%) and routine (85%) ones. Emergency (26%), lack of counting (25%) and inadequate conditions of work contributed (12.5%) to the occurrence. In 46% of the cases patients were alerted about the FB, and 26% of them sued the doctors or the institution. CONCLUSIONS: challenging medical situations, omission of security protocols and inadequate work conditions contributed to RFB. However, RFB occurs mostly in routine procedures such as cesarean or cholecystectomy, and at the beginning of the professional career, highlighting, particularly in poorest countries, the need for primary prevention. Textiles predominated causing clinical repercussions and they were diagnosed in the first postoperative months. Surgeons were sued in 11.3% of the RFB cases. AD - Faculdade de Medicina, Universidade de São Paulo, SP, Brasil. AN - 27096851 AU - Birolini, D. V. AU - Rasslan, S. AU - Utiyama, E. M. DA - Feb DO - 10.1590/0100-69912016001004 DP - NLM ET - 2016/04/21 IS - 1 KW - Brazil Cross-Sectional Studies *Foreign Bodies/epidemiology/etiology Humans Self Report Surgical Procedures, Operative LA - eng por N1 - 1809-4546 Birolini, Dário Vianna Rasslan, Samir Utiyama, Edivaldo Massazo Journal Article Observational Study Brazil Rev Col Bras Cir. 2016 Feb;43(1):12-7. doi: 10.1590/0100-69912016001004. PY - 2016 SN - 0100-6991 SP - 12-7 ST - Unintentionally retained foreign bodies after surgical procedures. Analysis of 4547 cases T2 - Rev Col Bras Cir TI - Unintentionally retained foreign bodies after surgical procedures. Analysis of 4547 cases VL - 43 ID - 176 ER - TY - JOUR AB - A 79-year-old male patient was followed for unilateral uveitis with 3 attacks in 10 months, despite initial improvement with steroid therapy. The patient had visual acuity (VA) of counting fingers in right eye, hypopyon and vitritis with no chorioretinal lesions. The left eye was normal. The patient was evaluated for intraocular foreign body, intraocular lymphoma and associated systemic disease and malignancy. Computed tomography of the abdomen showed a mass in the bladder. Biopsy confirmed bladder carcinoma. After resection of the mass, intraocular inflammation improved completely and no attack was noted in the follow-up. In his last examination, two years after the operation, VA was light perception; seclusio pupilla and mature cataracts were seen on biomicroscopy. There was no sign of vitritis on ocular ultrasonography. Evidence is discussed that suggests a link and potential etiology between refractory uveitis with hypopyon and bladder carcinoma. This is the first case of unilateral recurrent uveitis with hypopyon as the initial presenting sign of bladder carcinoma. AD - Necmettin Erbakan University Meram Faculty of Medicine, Department of Ophthalmology, Konya, Turkey. Necmettin Erbakan University Meram Faculty of Medicine, Department of Pathology, Konya, Turkey. AN - 28058157 AU - Şatırtav, G. AU - Donbaloğlu, M. AU - Oltulu, R. AU - Oltulu, P. AU - Kerimoğlu, H. AU - Özkağnıcı, A. C2 - PMC5200827 DA - Aug DO - 10.4274/tjo.92259 DP - NLM ET - 2017/01/07 IS - 4 KW - Anterior uveitis bladder carcinoma paraneoplastic syndrome authors declared that this study received no financial support. LA - eng N1 - 2149-8709 Şatırtav, Günhal Donbaloğlu, Meryem Oltulu, Refik Oltulu, Pembe Kerimoğlu, Hürkan Özkağnıcı, Ahmet Journal Article Turk J Ophthalmol. 2016 Aug;46(4):190-193. doi: 10.4274/tjo.92259. Epub 2016 Aug 15. PY - 2016 SN - 2149-8695 (Print) 2149-8709 SP - 190-193 ST - Unilateral Recurrent Anterior Uveitis as the Presenting Sign of Bladder Carcinoma T2 - Turk J Ophthalmol TI - Unilateral Recurrent Anterior Uveitis as the Presenting Sign of Bladder Carcinoma VL - 46 ID - 186 ER - TY - JOUR AB - Introduction Central venous catheterisation is an essential component of patient care in hospital. A forgotten complete guide-wire is a rare complication, although the reported incidence has increased rapidly over the last decade. Case report We report a 72-year-old man with a complete guide-wire inadvertently overlooked during catheter insertion. A central venous catheter had been inserted for total parental nutrition during treatment for pancreatitis. Five years later, the patient was readmitted with a painful lesion on his neck and the sensation of a sharp object under his skin. He was discharged without complication following removal of the free part of the guide-wire that had not become attached to the endothelial layer. Conclusion Inattention, inexperience and lack of supervision by a more experienced clinician are considered the most important contributing factors to this complication. Ultrasonography assistance during the procedure, senior supervision, a set count and a chest X-ray after the procedure are recommended in order to prevent forgotten guide-wires. AD - 1 Cardiovascular surgeon, Department of Cardiovascular Surgery, Kanuni Research and Training Hospital, Turkey. 2 Assistant doctor, Department of Cardiovascular Surgery, Faculty of Medicine, Karadeniz Technical University, Turkey. 3 Cardiovascular surgeon, Assistant professor, Department of Cardiovascular Surgery, Faculty of Medicine, Karadeniz Technical University, Turkey. AN - 29226770 AU - Hemsinli, D. AU - Mutlu, H. AU - Altun, G. AU - Pulathan, Z. AU - Ozdemir, A. C. DA - Nov DO - 10.1177/0036933017699505 DP - NLM ET - 2017/12/12 IS - 4 KW - Aged Catheterization, Central Venous/*adverse effects Clinical Competence/*standards/statistics & numerical data Device Removal Foreign Bodies/*diagnostic imaging *Guideline Adherence Humans Iatrogenic Disease Jugular Veins/*diagnostic imaging Male Neck Pain/*diagnostic imaging/surgery Practice Guidelines as Topic Radiography, Thoracic Cardiovascular risk complication percutaneous intervention LA - eng N1 - Hemsinli, Dogus Mutlu, Hasan Altun, Gokalp Pulathan, Zerrin Ozdemir, Ahmet C Case Reports Journal Article Scotland Scott Med J. 2017 Nov;62(4):156-158. doi: 10.1177/0036933017699505. Epub 2017 Mar 14. PY - 2017 SN - 0036-9330 (Print) 0036-9330 SP - 156-158 ST - An unexpected image on a chest radiograph T2 - Scott Med J TI - An unexpected image on a chest radiograph VL - 62 ID - 203 ER - TY - JOUR AN - 104056705. Language: English. Entry Date: 20140328. Revision Date: 20200708. Publication Type: Journal Article DB - ccm DO - 10.1016/j.aorn.2014.01.020 DP - EBSCOhost IS - 4 KW - Retained Instruments Male Aged Retained Instruments -- Risk Factors Retained Instruments -- Complications Retained Instruments -- Diagnosis Failure to Diagnose Surgical Count Procedure Adverse Health Care Event Coronary Artery Bypass Mitral Valve -- Surgery Empyema -- Etiology Surgical Instruments Rubber N1 - case study. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Patient Safety; Perioperative Care. NLM UID: 0372403. PMID: NLM24674800. PY - 2014 SN - 0001-2092 SP - 556-509 ST - Undetected Foreign Object T2 - AORN Journal TI - Undetected Foreign Object UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104056705&site=ehost-live&scope=site VL - 99 ID - 821 ER - TY - JOUR AB - The diversity of endothelial cell deletion in regressing blood vessels during involution of granulation tissue was investigated in foreign-body granulomas induced by a collagen sponge implanted into the dorsum of the rat. Small blood vessel density counts were performed to determine the degree of blood vessel regression in the involution of granulation tissue in foreign-body granuloma. The density of these small blood vessels significantly decreased between 100 and 130 days after sponge implantation. The detachment of endothelial cells from their underlying basement membrane and the consequent protrusion into and/or out of the lumen in the vascular network of granulation tissue was observed by electron microscopy. Based on the pattern of manifestation in the endothelium and the characteristic deformation of nuclei, the detached endothelial cells were classified into two groups: 1) the endothelial cell apoptosis group and 2) the endothelial cell degeneration group. The essential difference between the two groups was easily distinguishable as the nucleus of the former group displayed chromatin condensation and margination as the hallmark of early apoptotic changes, while the nucleus of the latter group displayed a pinch structure and intranuclear pocket formation. However, the process by which the detached endothelial cells were shed into the vascular lumen and eventually eliminated from circulation was the same in both groups. The occurrence of both groups increased on the 90th day after sponge implantation and reached a maximum on the 110th day, indicating that the appearance of the groups was synchronized. These results suggest that the two major processes of apoptosis and degeneration of endothelial cells occur during endothelial cell deletion as a mechanism contributing to blood vessel regression. AD - Department of Pharmacology, Kawasaki Medical School, Kurashiki, Japan Dept. of Plast. and Reconstr. Surg., Kawasaki Medical School, Kurashiki, Japan Department of Pharmacology, Kawasaki Medical School, Kurashiki City, 701-0192 Okayama, Japan AU - Honma, T. AU - Hamasaki, T. DB - Scopus IS - 1 KW - Apoptosis Degeneration Endothelial cells Granulation tissue Involution M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 1998 SP - 31-44 ST - Ultrastructure of blood vessel regression in involution of foreign-body granuloma T2 - Journal of Submicroscopic Cytology and Pathology TI - Ultrastructure of blood vessel regression in involution of foreign-body granuloma UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031612601&partnerID=40&md5=e6639c4a3db617e5a00dd6e31ebaca6f VL - 30 ID - 1700 ER - TY - JOUR AB - Gastrointestinal stromal tumors (GIST) have a variety of appearances and can present as an intraluminal, extraluminal, solid or ulcerated mass. We present an unusual case of a patient presenting with pain, elevated white count, and computed topography (CT) findings suggesting an abscess containing bone. CT guided drainage was performed, and resulted in bowel perforation, leading to surgical intervention and the diagnosis of an ulcerated gastrointestinal stromal tumor containing bone. AN - 27298690 AU - Kriegshauser, J. S. AU - Hara, A. K. C2 - PMC4891552 DO - 10.2484/rcr.v1i3.30 DP - NLM ET - 2006/01/01 IS - 3 KW - BP, blood pressure CT, computed topography EGD, esophagogastroduodenoscopy GIST, gastrointestinal stromal tumor PET, positron emitting tomography WBC, white blood cell LA - eng N1 - 1930-0433 Kriegshauser, J Scott Hara, Amy K Case Reports Radiol Case Rep. 2015 Nov 6;1(3):83-6. doi: 10.2484/rcr.v1i3.30. eCollection 2006. PY - 2006 SN - 1930-0433 (Print) 1930-0433 SP - 83-6 ST - Ulcerated Gastrointestinal Stromal Tumor (GIST) with Ingested Bone Foreign Body Mimicking a Perforation with Abscess T2 - Radiol Case Rep TI - Ulcerated Gastrointestinal Stromal Tumor (GIST) with Ingested Bone Foreign Body Mimicking a Perforation with Abscess VL - 1 ID - 57 ER - TY - JOUR AB - Necrosis of tympanic membrane (TM) can be due to infections, drugs, radiation, and foreign body. Strain of group A Streptococcus is associated with acute otitis media or in immunocompromised individuals resulting in TM necrosis. Gangrene of lower limb has been described, but the selective loss of TM due to emboli is an uncommon finding. A 62-year-old female presented with sudden behavioral changes and irrelevant talk. After 2 days, she noticed a discharge from left ear. There was perforation of left TM in posterior superior and inferior quadrant with areas of the black patch around the perforation suggesting a loss of blood supply. Patient was recently detected retrovirus positive with multiple lung shadows. Patient is not on any anti-retroviral medications or other medications. The discharge started 2 days after an episode of left middle cerebral artery infarct due to emboli with no previous history of ear symptoms. Culture of discharge showed no growth. This suggests that TM might have gone for gangrene due to emboli affecting deep auricular artery branch or posterior tympanic branch, which is a branch of the stylomastoid artery. AD - Department of ENT, M. S. Ramaiah Medical College, MSRIT Post, Bengaluru, Karnataka, 560 054, India AU - Surya Prakash, D. R. AU - Hussain, A. DB - Scopus DO - 10.4103/0971-7749.159711 IS - 3 KW - Blood supply Gangrene Necrosis Stylomastoid artery Tympanic membrane M3 - Article N1 - Export Date: 10 November 2020 PY - 2015 SP - 219-221 ST - Tympanic membrane gangrene T2 - Indian Journal of Otology TI - Tympanic membrane gangrene UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84937893659&doi=10.4103%2f0971-7749.159711&partnerID=40&md5=dfd3d96beb0f1dd9e44a4c467a6111c8 VL - 21 ID - 1251 ER - TY - JOUR AB - Objectives: The term 'retained surgical items' refers to any object which, unintentionally, remains inside the patient's body after the surgery, once the skin is closed. This implies a medical error which may lead to medical complications and medical-legal and economic consequences. Our aimas were: (1) to expose two cases of patients treated at our Hospital during 2018 in which retained surgical items from a previous surgery were found (cholecystectomy) after coming to the Emergency Room with abdominal pain, and (2) to study the rate, risk factors, clinical features, diagnosis and treatment of retained surgical items and review updated prevention strategies. Methods: The information from both cases was collected by reviewing the medical history and surgical reports saved in OsabideGlobal, aDUHprogram.We carried out a bibliographic review with the searches: 'surgery iatrogenia foreign body', 'foreign bodies after surgery' and 'retained surgical item' in databases such as UpToDate, Dynamed and Clinical Key Results: The rate at which this occurs can vary. In abdominal cavity surgeries it happens to about 1 out of every 1,000 to 1,500 patients. Among the associated risk factors we can find: emergency surgery, surgery with blood loss >500 ml, erroneous or not performed surgical count, performing more than one procedure in surgery, long surgeries, unexpected changes during the course of surgery and surgery in patients with raised BMI. There are two patterns of clinical presentation of surgical sponge retention: exudative and fibrous pattern. The diagnosis is based on image studies that show the retained object. The trapped object must be removed in symptomatic patients. Observation is accepted in asymptomatic patients when the objects are held for a long time or if they account for a significant amount of comorbidity. There are multiple prevention strategies such as improving the communication among the operating room staff, or the accuracy in counting, among others. Conclusions: Even though there have been many cases of retained surgical items in the past, there are very few publications. Despite the progress made, it is an adverse event that continues to occur. Surgical count plays a main role in the prevention. AD - E. Varela, Hospital Universitario Donostia, San Sebastián, Spain AU - Varela, E. AU - Iraola Fernández De Casadevante, M. AU - De Ariño Hervás, I. AU - Aguirre Allende, I. AU - García Trancho, A. AU - Ruiz Montesinos, I. AU - Enríquez Navascués, J. M. DB - Embase IS - SUPPL, 1 KW - abdominal cavity abdominal pain adult bleeding body mass cholecystectomy clinical feature comorbidity conference abstract emergency surgery emergency ward female foreign body human major clinical study male operating room patient history of surgery risk factor surgery surgical sponge LA - English M3 - Conference Abstract N1 - L631943054 2020-06-09 PY - 2020 SN - 1365-2168 SP - 16 ST - Two cases report of retained surgical items T2 - British Journal of Surgery TI - Two cases report of retained surgical items UR - https://www.embase.com/search/results?subaction=viewrecord&id=L631943054&from=export VL - 107 ID - 287 ER - TY - JOUR AB - Bowel obstruction due to bezoars (compaction of ingested material within the gastrointestinal tract) is a rare, but well documented occurrence. In this paper, we present two cases of potato-induced small bowel obstruction. Both patients were approximately 50 years old and had cerebral palsy and learning disabilities, respectively. They presented with abdominal pain and bilious vomiting, with no medical or surgical history. Diagnosis of small bowel obstruction was confirmed by CT prior to taking the patients to the operating theatre, where whole potatoes were found to be obstructing each patient's bowel lumen. Both patients underwent laparotomy with enterotomy and removal of the potato. They both made a good recovery. Through a literature review of bezoar-induced bowel obstruction, these cases highlight important diagnostic and management principles. Copyright 2015 BMJ Publishing Group. All rights reserved. AD - Department of General and Colorectal Surgery, James Paget University Hospital NHS Trust, Gorleston-on-Sea, United Kingdom Department of Radiology, James Paget University Hospital NHS Trust, Gorleston-on-Sea, United Kingdom AU - Castren, E. AU - Hakeem, A. AU - Mahmood, N. S. AU - Aryal, K. C7 - 213744 DB - Scopus DO - 10.1136/bcr-2015-213744 M3 - Article N1 - Export Date: 10 November 2020 PY - 2015 ST - Two cases of small bowel obstruction secondary to a swallowed potato T2 - BMJ Case Reports TI - Two cases of small bowel obstruction secondary to a swallowed potato UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84954445026&doi=10.1136%2fbcr-2015-213744&partnerID=40&md5=192137557505ad3b9c5a18422dfaf91a VL - 2015 ID - 1212 ER - TY - JOUR AB - Introduction: Intrathoracic textiloma is a rare complication possibly leading to misdiagnosis. It could present as haemoptysis, lung abscess, pseudo-tumour or a chronic cough. Case report: A 65-year-old patient with a history of multiple cardiac problems and needing long-term anticoagulation, complained since 2007 of recurrent haemoptysis of increasing abundance, the etiological investigation of which was negative. A thoracic CT-scan revealed a lesion in the lingula in contact with the pericardial plates of an implanted automatic defibrillator dating from 1989. In 2016, after two failures of arterial embolization, a diagnostic and therapeutic surgical exploration was undertaken on this patient who was a high operative risk. A segmental resection revealed an intra-pulmonary textiloma on pathological examination. Conclusion: The diagnosis of intrathoracic textiloma remains rare and its late presentation is non specific. Radiological imaging with a CT-scan and/or MRI could lead to the diagnosis. Surgery remains the reference treatment for the diagnosis and cure of intrathoracic textiloma with pathological examination, essential for confirmation. A means of prevention has to be developed because swab count is not totally reliable. AD - L. Lebas, Service de pneumologie, hôpital Larrey, CHU de Toulouse, Toulouse, France AU - Lebas, L. AU - Dupuis, M. AU - Solovei, L. AU - Jaffro, M. AU - Grunenwald, E. AU - Pontier-Marchandise, S. AU - Dahan, M. AU - Didier, A. DB - Embase Medline DO - 10.1016/j.rmr.2018.04.009 IS - 2 KW - implantable cardioverter defibrillator adult anticoagulant therapy arterial embolization article case report clinical article computer assisted tomography foreign body hemoptysis histopathology human intrathoracic textiloma middle aged thorax disease thorax surgery LA - English French M3 - Article N1 - L2001278345 2018-11-19 2019-03-14 PY - 2019 SN - 1776-2588 0761-8425 SP - 214-218 ST - Twenty years later… A story of intra-thoracic textiloma T2 - Revue des Maladies Respiratoires TI - Twenty years later… A story of intra-thoracic textiloma UR - https://www.embase.com/search/results?subaction=viewrecord&id=L2001278345&from=export http://dx.doi.org/10.1016/j.rmr.2018.04.009 VL - 36 ID - 320 ER - TY - JOUR AB - Tumorilysin was found in diffusion chambers implanted s.c. or i.p. in A/BiF/F50+, DBA/2J and C57BL/6J mice. Chambers with 0.45-µm pores implanted s.c. were most densely covered by a syncytium of macrophages and had the most consistently active tumorilysin, compared with smaller-pored chambers or those implanted i.p. The lysin acted on cultures of murine sarcomas induced by foreign bodies, murine and human mammary carcinoma, and human lymphoma. Lysis was demonstrable within 15 min. There was a dose-response relationship between residual cell counts in cultures and concentrations of diffusion chamber fluid between 1.5 and 12.5%. Murine fibroblasts in culture were not lysed by tumorilytic fluid. The incidence of sarcomas induced by 15-mm vinyl squares implanted s.c. in A/BiF/F50+ mice was significantly reduced at 64 weeks in each of 4 experiments by 2 or 3 injections of 0.05 ml diffusion chamber fluid within the capsule on each side at 2 to 42 weeks after implantation. Analyses of the fluid, compared with serum, for the following substances showed no correlation with tumorilysis: cathepsin D; neutral protease; complement C3 fraction; and arginase. Tumorilysin was preserved by lyophilization and was destroyed by heating to 56° it did not pass filters cutting off at m.w. 300,000. © 1980, American Association for Cancer Research. All rights reserved. AD - Department of Surgery, University of Chicago, Chicago, United States AU - Ferguson, D. J. AU - Urban, J. L. DB - Scopus IS - 4 M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 1980 SP - 1255-1262 ST - Tumorilysin Collected in Diffusion Chambers and Restraint of Foreign T2 - Cancer Research TI - Tumorilysin Collected in Diffusion Chambers and Restraint of Foreign UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0018860088&partnerID=40&md5=d7b3a037bdd76bcd9729d8d46634985c VL - 40 ID - 1766 ER - TY - JOUR AB - A 39-year-old housewife sustained inadvertent trauma to the right index finger about 6 years ago, whilst stitching clothes. A couple of weeks later, the site of trauma became hard and gritty. Ever since, it has progressed slowly, without any appreciable outward sign. It was not associated with any discomfort /pain. Consequent on an opinion from a surgeon, it was decided to operate on the right index finger. During the operation, under local anesthesia, a hard and gritty material was removed. The material was subjected to histopathologic study. Several stitches were applied to the wound. It failed to respond to antimicrobial therapy over a 4-week period, prompting the patient to seek another opinion. Examination of the skin surface revealed a plaque with an irregular configuration on and around the distal interphalangeal joint of the right index finger. It was erythematous and pigmented. The top of the plaque was irregular and had alternating elevations and depressions (Fig. 1). Diascopy was negative for apple jelly nodule. A bacillus Calmette-Guérin (BCG) vaccination scar was identified on the left deltoid. There was no regional lymphadenopathy or systemic abnormality. Mantoux test with intradermal injection of 0.1 mL SPAN's tuberculin (purified protein derivative/5 tuberculin units/0.1 mL) (Span Diagnostic Ltd., Murat, India) was negative after 72 h. Investigations, including total and differential leukocyte count, erythrocyte sedimentation rate, serum biochemistry, and renal and liver function tests, were within the normal range, as was a chest X-ray. Hematoxylin and eosin-stained sections prepared from the biopsy taken from the lesion revealed noteworthy changes in the epidermis and the dermis. The former was marked by the presence of hyperkeratosis, acanthosis, and papillomatosis, whilst the latter contained tubercle granulomas. Each of the granulomas was well formed and consisted of large numbers of lymphocytes, histiocytes, and foreign body (Langerhans') giant cells (Fig. 2). Caseation necrosis and acid-fast bacilli could not be demonstrated. The preceding revelations were fairly conducive to the diagnosis. Accordingly, antitubercular therapy (ATT), comprising 450 mg of rifampicin, 300 mg of isonicotinic acid hydrazide, and 800 mg of ethambutol, was recommended for oral administration each day for 60 days. The outcome of the treatment was satisfactory, resulting in perceptible regression of the skin lesion (Fig. 1b). The patient was advised to continue the treatment for another 30 days, after which 450 mg of rifampicin and 300 mg of isonicotinic acid hydrazide were to be continued for another 6 months. © 2004 The International Society of Dermatology. AD - V.N. Sehgal, A/6 Panchwati, Azadpur, Delhi 110 033, India AU - Sehgal, V. N. AU - Sardana, K. AU - Bajaj, P. AU - Bhattacharya, S. N. DB - Embase Medline DO - 10.1111/j.1365-4632.2004.02019.x IS - 3 KW - antiinfective agent BCG vaccine eosin ethambutol hematoxylin isoniazid rifampicin tuberculostatic agent acanthosis adult article BCG vaccination case report clinical feature dermis diagnostic procedure disease course epidermis female histopathology human human tissue hyperkeratosis papillomatosis patient satisfaction physical examination skin biopsy skin injury skin tuberculosis surgical technique treatment outcome LA - English M3 - Article N1 - L40425669 2005-04-11 PY - 2005 SN - 0011-9059 SP - 230-232 ST - Tuberculosis verrucosa cutis: Antitubercular therapy, a well-conceived diagnostic criterion T2 - International Journal of Dermatology TI - Tuberculosis verrucosa cutis: Antitubercular therapy, a well-conceived diagnostic criterion UR - https://www.embase.com/search/results?subaction=viewrecord&id=L40425669&from=export http://dx.doi.org/10.1111/j.1365-4632.2004.02019.x VL - 44 ID - 631 ER - TY - JOUR AB - LEARNING OBJECTIVE 1: Recognize that catastrophic sequela of blunt abdominal trauma can occur many weeks after the event. LEARNING OBJECTIVE 2: Recognize radiological mimickers of intussusception and small bowel obstruction. CASE: A previously healthy 38 year-old man presented with abdominal distention, nausea, and vomiting. Two weeks prior, he was admitted to an outside hospital with the same symptoms. At the time, computerized tomography (CT) scan showed small bowel obstruction (SBO) with transition point in the left mid-abdomen and terminal ileum wall thickening. He was treated with nasogastric tube decompression, but left against medical advice without a diagnosis when his symptoms improved. He presented to our emergency department with recurrentf abdominal distention and new feculent emesis. He denied fevers, chills, blood in his stool, melena, or history of abnormal bowel movements. He reported that three weeks prior to the first hospitalization, he had suffered a bicycle collision in which the handlebars struck his abdomen, resulting in severe abdominal pain. There had been no open wound or blood per rectum after the accident. On physical exam at the time of admission, he had normal vital signs and mild abdominal distention and tenderness. Laboratories showed normal complete blood count, electrolytes, aminotransferases, bilirubin, and lipase. CT scan of the abdomen and pelvis with intravenous contrast showed wall thickening of the distal jejunum and proximal ileum, probable ileal enteroenteric fistula, two segments of jejunojejunal intussusception with upstream bowel dilation, and diffuse lymphadenopathy. Taken together, the findings were thought to be most consistent with inflammatory bowel disease (IBD). Unfortunately, before a diagnostic colonoscopy was done, the patient ate a large meal. Overnight, he developed severe abdominal pain, went into shock and was taken emergently to the operating room. He was found to have obstruction of the terminal ileum due to an adhesion and upstream perforation with food in the peritoneal cavity. He underwent resection of 140 centimeters of terminal ileum and end-ileostomy. Final pathology showed a mixed acute and chronic inflammatory reaction within the serosa associated with small vessel proliferation, organization, and foreign material; there was no evidence of IBD or cancer. The diagnosis was felt to be intussusception and SBO as a result of intestinal trauma from his bicycle accident. DISCUSSION: Inpatient providers often care for patients with undifferentiated SBO. Blunt abdominal trauma can cause injury to the mesentery, hemorrhagic mucosal infarction, and subclinical bowel perforation. Subsequent healing with fibrosis and stricture can lead to intussusception and SBO with a delayed onset of symptoms. Intussusception and SBO after abdominal trauma are rare; there are 22 reports representing 91 cases in the literature. Patients typically present with intermittent abdominal pain and vomiting within 4 to 8 weeks of the trauma, but symptoms can be delayed by years. Diagnostic criteria include (1) prior blunt abdominal trauma, (2) absence of intestinal disease, (3) new intestinal symptoms, (4) radiographic confirmation of stenosis, and (5) lack of inflammatory or neoplastic changes in resected segment of bowel. In managing patients with abdominal pain or SBO, inpatient providers should consider prior blunt abdominal trauma in the differential and appreciate the variable timing in symptom onset. AD - M. Shoeb, UCSF, San Francisco, CA, United States AU - Shoeb, M. AU - Wlodarczyk, S. AU - Mookherjee, S. DB - Embase KW - bilirubin electrolyte aminotransferase triacylglycerol lipase society internal medicine intestine obstruction human intussusception patient abdominal blunt trauma abdominal pain diagnosis ileum intestine abdomen computer assisted tomography bicycle hospital patient small intestine obstruction blood vomiting injury accident operating room colonoscopy inflammatory bowel disease fever hospital fistula jejunum pelvis emergency ward nausea and vomiting blood cell count decompression laboratory intestine perforation stenosis vital sign nasogastric tube rectal drug administration lymphadenopathy mesentery wound intestine injury foreign body inflammation hospitalization pathology ileostomy serosa surgery neoplasm peritoneal cavity melena food perforation adhesion obstruction infarction healing fibrosis abdominal injury enteropathy male LA - English M3 - Conference Abstract N1 - L71297419 2014-01-24 PY - 2012 SN - 0884-8734 SP - S494-S495 ST - True-true-related: An unusual cause of bowel obstruction T2 - Journal of General Internal Medicine TI - True-true-related: An unusual cause of bowel obstruction UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71297419&from=export VL - 27 ID - 511 ER - TY - JOUR AB - OBJECTIVES: To observe the frequency of eosinophilic esophagitis (EoE), pattern of clinical presentation and diagnosis among Saudi children at 2 tertiary carehospitals in Riyadh, Saudi Arabia. METHODS: The database of children admitted or seen, and aged less than 18 years over 5 years period and diagnosed with EoE was collected and reviewed. Patients with esophagitis other than EoE were excluded. Patients who had eosinophils count more than 15/high power field (HPF) on esophageal biopsies were given the diagnosis of EoE. Demographic database, clinical parameters, and diagnostic modalities were analyzed by using the Statistical Package for Social Sciences version 22. RESULTS: A total of 37 children with the diagnosis of EoE were gathered from 398 upper gastrointestinal endoscopic procedures with the frequency of 9.3%. There were 22 (59.4%) males with a mean±SD age of 9.6±2.3 years and all were Saudi nationals. Dysphagia was the leading presentation in 21 (56.7%) children followed by vomiting in 18 (48.6%), impaction of food bolus in 8 (21.6%) and foreign body in 3 (8.1%). Allergic symptoms were present in 13 (35.1%) children in the form of asthma, 11 (29.7%) multiple food allergies and 5 (13.5%) eczema. Peripheral eosinophil count and immunoglobulin E were raised more than normal in 6 and 5 children respectively. The pH measurements were carried out in 16 (43.2%) and ruled out the reflux. Contrast studies with barium (n=6; 16.2%) and endoscopic findings were significant (n=27; 72.9%). CONCLUSION: Eosinophilic esophagitis is an emerging disease and have a rising trend in Saudi children. Dysphagia, vomiting, and food impaction are the more common presenting features in older children and recurrent vomiting in younger children in addition to associated allergic conditions. AD - Division of Pediatric Gastroenterology, Hepatology & Nutrition, Department of Pediatric Medicine, College of Medicine, King Saud University Medical City, Riyadh, Kingdom of Saudi Arabia. E-mail. anjuj2002@hotmail.com. AN - 29968888 AU - Saeed, A. AU - Assiri, A. M. AU - Al Asmi, M. AU - Ullah, A. C2 - PMC6146256 DA - Jul DO - 10.15537/smj.2018.7.22425 DP - NLM ET - 2018/07/04 IS - 7 KW - Child Child, Preschool Cross-Sectional Studies Deglutition Disorders/etiology Eosinophilic Esophagitis/complications/diagnosis/*epidemiology/pathology Esophageal Stenosis/etiology Esophageal pH Monitoring Esophagoscopy Female Foreign Bodies/etiology Humans Male Retrospective Studies Saudi Arabia/epidemiology Tertiary Care Centers Vomiting/etiology LA - eng N1 - Saeed, Anjum Assiri, Asaad M Al Asmi, Mona Ullah, Anhar Journal Article Saudi Med J. 2018 Jul;39(7):668-673. doi: 10.15537/smj.2018.7.22425. PY - 2018 SN - 0379-5284 (Print) 0379-5284 SP - 668-673 ST - Trend, clinical presentations and diagnosis of eosinophilic esophagitis in Saudi children T2 - Saudi Med J TI - Trend, clinical presentations and diagnosis of eosinophilic esophagitis in Saudi children VL - 39 ID - 216 ER - TY - JOUR AB - Foreign body-associated infectious disease is currently one of the most problematic hospital-acquired infections. Patients with placement of urinary catheters are especially susceptible to such infection, that is biofilm infection. In this study, we focused on the therapeutic efficacy of prulifloxacin (PUFX) against Pseudomonas aeruginosa OP 14-210, isolated from a patient with complicated urinary tract infection. This microbe formed a biofilm on the surface of a polyethylene tube (PT) placed in a rat bladder without surgical manipulation. In addition, we attempted to eradicate the biofilm by treatment with a combination of PUFX and fosfomycin (FOM). A single oral administration of PUFX at a dose of 20 mg/kg was effective against P. aeruginosa as a biofilm, yielding a significant reduction in CFU per PT of approximately 1 log(10) CFU/PT compared with that in untreated controls. A similar therapeutic effect was also observed in levofloxacin-treated rats, and albeit slightly weaker, in ciprofloxacin-treated animals as well. Because 3 days' consecutive treatment with each fluoroquinolone did not further decrease the viable cell counts on the PT, we tested the efficacy of combining PUFX and FOM. These two drugs, administered once a day for 3 days, at doses of 20 and 100 mg/kg, respectively, resulted in significant decreases of viable cell counts on the PT of more than 1.5 log(10) CFU/PT compared with PUFX alone (P < 0.05). As seen by scanning electron microscopy, destruction and disappearance of multilayer biofilms occurred after treatment with this drug combination. Such combination therapy with PUFX and FOM may be advantageous for treating biofilm-related infectious diseases. AD - Pharmacology Research Labs., Pharmaceutical Research Center, Meiji Seika Kaisha, Ltd., Morooka-Cho 760, Kohoku-ku, Yokohama 222-8567, Japan. takeshi_mikuniya@meiji.co.jp AN - 17982715 AU - Mikuniya, T. AU - Kato, Y. AU - Ida, T. AU - Maebashi, K. AU - Monden, K. AU - Kariyama, R. AU - Kumon, H. DA - Oct DO - 10.1007/s10156-007-0534-7 DP - NLM ET - 2007/11/06 IS - 5 KW - Animals Anti-Bacterial Agents/*pharmacology Biofilms/*growth & development Catheters, Indwelling/adverse effects/microbiology Dioxolanes/*pharmacology Disease Models, Animal Drug Therapy, Combination Female Fluoroquinolones/*pharmacology Fosfomycin/*pharmacology Humans Microbial Sensitivity Tests Microscopy, Electron, Scanning Piperazines/*pharmacology Polyethylene Pseudomonas Infections/*drug therapy/microbiology Pseudomonas aeruginosa/drug effects/growth & development/isolation & purification/*physiology Quinolones/*pharmacology Rats Urinary Catheterization/adverse effects Urinary Tract Infections/*drug therapy/microbiology LA - eng N1 - Mikuniya, Takeshi Kato, Yoshihisa Ida, Takashi Maebashi, Kazunori Monden, Koichi Kariyama, Reiko Kumon, Hiromi Journal Article Netherlands J Infect Chemother. 2007 Oct;13(5):285-90. doi: 10.1007/s10156-007-0534-7. Epub 2007 Oct 30. PY - 2007 SN - 1341-321X (Print) 1341-321x SP - 285-90 ST - Treatment of Pseudomonas aeruginosa biofilms with a combination of fluoroquinolones and fosfomycin in a rat urinary tract infection model T2 - J Infect Chemother TI - Treatment of Pseudomonas aeruginosa biofilms with a combination of fluoroquinolones and fosfomycin in a rat urinary tract infection model VL - 13 ID - 69 ER - TY - JOUR AB - BACKGROUND: Pseudofolliculitis barbae (PFB) is a foreign body inflammatory condition that is caused by in-grown hairs of the face and body. An effective treatment to alleviate this condition without the risk of side effects has yet to be found. OBJECTIVE: The objective of this study was to evaluate the Lyra 1064-nm long-pulse ND:YAG laser in the treatment of PFB on skin types V and VI. METHODS: Twenty subjects (12 males and 8 females) were given two treatments approximately 3 to 4 weeks apart and were assessed by objective papule/pustule and hair counts at 1, 2, and 3 months after final treatment. Laser treatments with the Lyra Nd:YAG laser were applied onto 2x2-cm regions on the upper and lower mandible and neck regions. Contralateral controls were used to assess overall effectiveness. Subjective evaluations were also obtained from both subjects and investigators. Assessments of any abnormal side effects caused by laser treatment, including dyspigmentation and/or scarring, were also evaluated. RESULTS: A reduction in the quantity of papules/pustules and hairs when compared with baseline data was statistically significant for treatment of PFB in the mandibular and neck regions at the 1-, 2-, and 3-month follow-up evaluations. Subject evaluations ranged from satisfied to very satisfied. Side effects included transient hyperpigmentation, transient hypopigmentation, mild erythema, and itching. CONCLUSIONS: The use of the 1064-nm long-pulse Nd:YAG laser for the treatment and management of PFB on skin types V and VI is both safe and effective, with positive results lasting for up for to 3 months after two treatments. AD - Advanced Laser and Cosmetic Dermatology, 4007 GG Bellaire Boulevard, Houston, TX 77025, USA. smweavermd@aol.com AN - 14725660 AU - Weaver, S. M., 3rd AU - Sagaral, E. C. DA - Dec DO - 10.1111/j.1524-4725.2003.29387.x DP - NLM ET - 2004/01/17 IS - 12 KW - Facial Dermatoses/classification/*surgery Female Folliculitis/classification/*surgery Follow-Up Studies Humans *Laser Therapy/methods Male Neodymium Yttrium LA - eng N1 - Weaver, Seymour M 3rd Sagaral, Emelou C Journal Article United States Dermatol Surg. 2003 Dec;29(12):1187-91. doi: 10.1111/j.1524-4725.2003.29387.x. PY - 2003 SN - 1076-0512 (Print) 1076-0512 SP - 1187-91 ST - Treatment of pseudofolliculitis barbae using the long-pulse Nd:YAG laser on skin types V and VI T2 - Dermatol Surg TI - Treatment of pseudofolliculitis barbae using the long-pulse Nd:YAG laser on skin types V and VI VL - 29 ID - 46 ER - TY - JOUR AB - Objective: Penetrating trauma to the buttock is relatively common. Because of the location of the trauma and complicated peripheral anatomical structures, surgery to the area can be difficult. We report the cases of 2 patients who sustained penetrating trauma to the buttock and underwent operative treatment assisted by spinal endoscopy. Methods: With the rapid development of minimally invasive spine surgery techniques in recent years, especially the wide application of endoscopy, we treated 2 cases of penetrating trauma with endoscopic probing within the wound channel, followed by hemostasis and postoperative irrigation and drainage. Results: Drainage tubes were removed from the 2 patients within 7 days after the surgery. Their wounds were healing well and they were discharged from the hospital within 12 days. Conclusions: If there is no injury to the large blood vessels, intestines, or urinary system, satisfactory clinical results can be obtained using spinal endoscopy to probe, irrigate, and identify foreign objects, when combined with hemostasis, postoperative short-term irrigation and debridement, and the use of antibiotics. © The Author(s) 2019. AD - Department of Orthopedics, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Nanchang, Jiangxi, China Medical Department of Graduate School, Nanchang University, Nanchang, Jiangxi, China AU - Long, Z. S. AU - Nie, X. Y. AU - Zhang, Y. W. DB - Scopus DO - 10.1177/0300060519887303 IS - 1 KW - buttock minimally invasive open injury penetrating trauma soft tissues Spinal endoscopy M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 ST - Treatment of penetrating trauma to the buttock assisted by spinal endoscopy T2 - Journal of International Medical Research TI - Treatment of penetrating trauma to the buttock assisted by spinal endoscopy UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85078693552&doi=10.1177%2f0300060519887303&partnerID=40&md5=7ca0574f3c108456f3228dd7c6a8b8c1 VL - 48 ID - 1034 ER - TY - JOUR AB - Pericarditis due to Candida species is a rare clinical entity, associated with thoracic surgery and immunosuppression. We report here the second case of pericarditis due to Candida albicans in a heart transplant patient, which presented as tamponade approximately 3 weeks post transplant, in the absence of evidence of sternal osteomyelitis. The patient was treated with pericardiocentesis and a combination of caspofungin and fluconazole, but the patient ultimately required the explantation of retained epicardial leads and the creation of a pericardial window. This case illustrates that Candida species must be considered in the differential diagnosis in post-transplant pericarditis, and that foreign body removal is, as always, key in helping to resolve such infections. This case also demonstrates the first use of caspofungin with fluconazole to treat Candida pericarditis. We discuss the conflicting data regarding the use of caspofungin, alone or in combination therapy, in treating infections involving biofilms, such as the infected pericardium. Copyright © Blackwell Munksgaard 2006. AD - Department of Medicine, Division of Infectious Diseases, Columbia University Medical Center, New York, NY, United States Department of Medicine, Division of Infectious Diseases, Columbia University Medical Center, 622 W 168th Street, New York, NY 10032, United States AU - Puius, Y. A. AU - Scully, B. DB - Scopus DO - 10.1111/j.1399-3062.2006.00195.x IS - 3 KW - Candida albicans Cardiac transplant Caspofungin Pericarditis M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2007 SP - 229-232 ST - Treatment of Candida albicans pericarditis in a heart transplant patient T2 - Transplant Infectious Disease TI - Treatment of Candida albicans pericarditis in a heart transplant patient UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-34547811389&doi=10.1111%2fj.1399-3062.2006.00195.x&partnerID=40&md5=577e37dfa05cafea76123dbffa17813b VL - 9 ID - 1557 ER - TY - JOUR AB - Background: In black Africa, the severity of traumatic ocular emergencies (TOE) is increased by a lack of ophthalmologists and often inadequate or even the inexistence of surgical equipment. Objective: To make an inventory of the difficulties associated with the management of TOE at the ophthalmology department of the University Hospital of Brazzaville (UHB). Design: A retrospective study. Setting: The University Hospital of Brazzaville. Subjects: Records selected were those of patients seen for traumatic pathologies that could compromise the visual prognosis and require immediate surgical treatment. The patients seen for injuries of related structures of the eye were excluded. Types of lesion, consultation period, time of surgical treatment, clinical appearance of the eye and visual acuity (VA) at three months were analysed. Results: The frequency of TOE was 1.8%. The average age was 35 ± 4 years old. The average time for consultation and treatment were 35 ± 10 days and 74 ± 5.5 hours. These TOE were: Corneoscleral rupture (63.2%), vitreoretinal iron foreign body (16.8%), retinal detachment (15%), and macula hole (5%). At three months 73.2% of eyes did not see the light, 19.2% had a VA waving from light perception and counting fingers, and for 7.6% the best VA did not exceed three out of ten. Conclusion: In the UHB, the rate of blindness associated with TOE is high. Training of ophthalmologists and adapted surgical equipment should be a priority. © 2015, East African Medical Association. All rights reserved. AD - Ophthalmology department, University Hospital of Brazzaville, Marien Ngouabi University of Brazzaville, Congo AU - Atipo-Tsiba, P. W. DB - Scopus IS - 2 M3 - Article N1 - Export Date: 10 November 2020 PY - 2015 SP - 90-92 ST - Traumatic ocular emergencies: The difficulties associated with their care at the university hospital of brazzaville T2 - East African Medical Journal TI - Traumatic ocular emergencies: The difficulties associated with their care at the university hospital of brazzaville UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85087010756&partnerID=40&md5=e7defc3e0c621d95726c3f32762e2157 VL - 92 ID - 1234 ER - TY - JOUR AB - AIM: To explore the traumatic endophthalmitis in young children and the outcome of pars plana vitrectomy (PPV). METHODS: Twenty-two eyes of 22 cases of young children consecutive pediatric traumatic endophthalmitis treated and followed up between September 2014 and May 2018 were included. Aqueous humor or vitreous samples were taken for bacterial culture and sensitivity tests. Intravitreal antibiotics (norvancomycin and ceftazidime) injection, combined with 23-gauge PPV, were administered in 22 eyes. Silicone oil (SO; 5000 centistoke) tamponade or perfluoropropane gas (C(3)F(8)) was used in all patients. Main outcome measures were best-corrected visual acuity (BCVA) and retinal attachment, the ratio of penetrating injury, and the existence of intraocular foreign body. RESULTS: The mean age of patients was 6.9±2.2 (range, 3-10)y. All injured eyes suffered from penetrating ocular injury with retained intraocular foreign body in one eye. Bacterial culture was positive in only 2 eyes. The mean follow-up time was 21.1±4.7 (range, 12-30)mo. In the primary PPV, intravitreal antibiotics was administrated in all eyes, SO in 18 eyes, and C(3)F(8) in 4 eyes. The secondary operation of SO removal and C(3)F(8) endotamponade was performed in 16 eyes and a second SO endotamponade due to emulsification of the oil and retinal detachment (RD) was operated in 7 eyes underwent 3 to 11.5mo after primary PPV. A third operation was done in 7 eyes. The final intraocular pressure (IOP) was 8.9±1.8 (range, 6.9-11.4) mm Hg. The final BCVAs were 20/200 or better in 5, counting fingers in 2, and light perception to hand movement in 8 eyes. Whose (66.7%) had retinal injury exhibited worse BCVA (P=0.019, Fisher's exact test). Eyes underwent SO tamponade exhibited worse final BCVA than that with C(3)F(8) in the primary PPV (P=0.026, Fisher's exact test). CONCLUSION: Traumatic endophthalmitis in children is generally more severe and associated with more complicated surgical procedures. Most patients have retinal injury need multiple operations and the final BCVA is poor. Prevention of ocular trauma, especially in children, is still critical. AD - Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China. Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai 200011, China. AN - 32309176 AU - Zhou, Y. L. AU - Wang, Y. X. AU - Yao, T. T. AU - Yang, Y. AU - Wang, Z. Y. C2 - PMC7154189 DO - 10.18240/ijo.2020.03.06 DP - NLM ET - 2020/04/21 IS - 3 KW - pars plana vitrectomy pediatric penetrating eye injury traumatic endophthalmitis LA - eng N1 - 2227-4898 Zhou, Ya-Li Wang, Yi-Xiao Yao, Teng-Teng Yang, Yuan Wang, Zhao-Yang Journal Article Int J Ophthalmol. 2020 Mar 18;13(3):406-411. doi: 10.18240/ijo.2020.03.06. eCollection 2020. PY - 2020 SN - 2222-3959 (Print) 2222-3959 SP - 406-411 ST - Traumatic endophthalmitis and the outcome after vitrectomy in young children T2 - Int J Ophthalmol TI - Traumatic endophthalmitis and the outcome after vitrectomy in young children VL - 13 ID - 247 ER - TY - JOUR AB - Trauma is the leading cause of death for people younger than age 45 in the United States. To help prevent death or disability, critically injured trauma patients must reach definitive care within the "golden hour."Often, the perioperative team has no more than 10 minutes to prepare the room before a patient who has suffered multiple, critical, traumatic injuries is rushed into the OR. For the trauma patient's safety, the perioperative team must be diligent and use creative measures to efficiently ensure that all surgical counts are completed. Foregoing surgical counts places the trauma patient at an increased risk for unintentionally retained foreign objects. AD - Memorial Hermann Hospital, Houston, TX, USA. AN - 18323023 AU - Murdock, D. DA - Feb DO - 10.1016/j.aorn.2007.07.008 DP - NLM ET - 2008/03/08 IS - 2 KW - Abdominal Injuries/*nursing Adolescent Female Foreign Bodies/*prevention & control Humans Medical Errors/*prevention & control Multiple Trauma/*nursing Patient Care Team/organization & administration Perioperative Nursing Surgical Instruments/adverse effects Surgical Sponges/adverse effects Time Factors LA - eng N1 - Murdock, Darlene Case Reports Journal Article Review United States AORN J. 2008 Feb;87(2):322-8. doi: 10.1016/j.aorn.2007.07.008. PY - 2008 SN - 0001-2092 (Print) 0001-2092 SP - 322-8 ST - Trauma: when there's no time to count T2 - Aorn j TI - Trauma: when there's no time to count VL - 87 ID - 75 ER - TY - JOUR AB - PURPOSE: To evaluate the clinical outcomes of transscleral fixation of a foldable intraocular lens (IOL) in eyes that had pars plana lensectomy combined with pars plana vitrectomy for severe vitreoretinal disease. SETTING: Seoul National University Hospital, Seoul, Korea. METHODS: The medical records of 21 patients who had a transscleral fixation of a foldable IOL after previous vitrectomy combined with lensectomy for severe posterior segment pathology were reviewed. The underlying vitreoretinal diseases were complicated proliferative diabetic retinopathy (n = 9), proliferative vitreoretinopathy (n = 5), traumatic retinal detachment (n = 3), intraocular foreign body (n = 2), and uveitic retinal detachment (n = 2). The postoperative best corrected visual acuity (BCVA) was compared with the preoperative BCVA. Autorefractometry and keratometry measurements and central endothelial cell counts were evaluated 1 day preoperatively and 6 months postoperatively. RESULTS: The mean age of the patients was 54.5 years. The preoperative aphakic period ranged from 2 to 22 months. The visual acuity reached the preoperative BCVA by 2 months after surgery and was better than the preoperative BCVA at 6 months (P =.006) and at the final visit (P =.003). Six months postoperatively, the mean myopic shift by cycloplegic autorefractometry was -1.0 diopter (D) and the mean scalar shift in surgically induced keratometric cylinder, 1.0 D. The mean central corneal endothelial loss at 6 months was 6.7% (range 2.4% to 22.2%). The only vitreoretinal complications were a transient vitreous hemorrhage and a reopened macular hole that was reattached after fluid-gas exchange. CONCLUSION: Transscleral fixation of a foldable IOL was safe and led to favorable visual outcomes in aphakic vitrectomized eyes with previous severe vitreoretinal disease. AD - Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, South Korea. AN - 14709302 AU - Ahn, J. K. AU - Yu, H. G. AU - Chung, H. AU - Wee, W. R. AU - Lee, J. H. DA - Dec DO - 10.1016/s0886-3350(03)00338-9 DP - NLM ET - 2004/01/08 IS - 12 KW - Adult Aged Aphakia, Postcataract/etiology/*surgery Female Humans Lens Implantation, Intraocular/*methods *Lenses, Intraocular Male Middle Aged Retinal Diseases/surgery Sclera/*surgery *Suture Techniques Treatment Outcome Visual Acuity *Vitrectomy LA - eng N1 - Ahn, Jae Kyoun Yu, Hyeong Gon Chung, Hum Wee, Won Ryang Lee, Jin Hak Journal Article Research Support, Non-U.S. Gov't United States J Cataract Refract Surg. 2003 Dec;29(12):2390-6. doi: 10.1016/s0886-3350(03)00338-9. PY - 2003 SN - 0886-3350 (Print) 0886-3350 SP - 2390-6 ST - Transscleral fixation of a foldable intraocular lens in aphakic vitrectomized eyes T2 - J Cataract Refract Surg TI - Transscleral fixation of a foldable intraocular lens in aphakic vitrectomized eyes VL - 29 ID - 45 ER - TY - JOUR AB - Rectal prolapse is not uncommon in the pediatric age group. Occurring more frequently in boys than girls and most often during the period of toilet training, the condition is usually self-limited. Treatment typically consists of nonoperative measures. There are patients, however, in whom operative intervention becomes necessary. Operative procedures described are based largely on adult experience and the most common repairs involve the use of a foreign body (Ripstein procedure) or colonic resection. These procedures are of considerable magnitude and may be attended by significant morbidity. As a result, there is reluctance to apply these techniques in children. There exists, then, a place for an efficacious method of repair for large prolapses that incurs minimal morbidity. This report recounts our experience with the treatment of four children with rectal prolapse using a transsacral rectopexy. The results indicate minimal perioperative morbidity, discharge within a few days, with the mechanisms of fecal continence being preserved. The longest follow-up is 17 years with a mean follow-up of 9 years. The overall treatment of rectal prolapse in children is reviewed with specific emphasis upon the indications for and technique of the transsacral approach. AN - 6703518 AU - Chino, E. S. AU - Thomas, C. G., Jr. DA - Feb DP - NLM ET - 1984/02/01 IS - 2 KW - Child Child, Preschool Female Humans Male Methods Rectal Prolapse/*surgery Rectum/surgery Sacrum LA - eng N1 - Chino, E S Thomas, C G Jr Case Reports Journal Article United States Am Surg. 1984 Feb;50(2):70-5. PY - 1984 SN - 0003-1348 (Print) 0003-1348 SP - 70-5 ST - Transsacral approach to repair of rectal prolapse in children T2 - Am Surg TI - Transsacral approach to repair of rectal prolapse in children VL - 50 ID - 9 ER - TY - JOUR AB - Transoralgastric debridement for pancreatic abscess is one of the successful applications of NOTES in clinical practice. We present a case report as follows: a 71-year-old female was hospitalized due to acute biliary pancreatitis. Three weeks after onset, the secondary abdominal CT showed a peripancreatic abscess. A passageway between the gastric wall and the abscess was made with a high-frequency puncher under the guidance of an ultrasonic gastroscope and then a gastroscope was directly inserted into the abscess, and a large amount of solid necrotic tissue was taken out with foreign body forceps and snare under the direct vision of a gastroscope. Then a 8.5F double-J stent and a nasobiliary drainage tube were inserted. After three times of intra-abdominal abscess debridement and repeated rinsing with an antibiotic solution, abdominal CT revealed the intra-abdominal abscess nearly disappeared and the patient discharged from hospital. © H.G.E. Update Medical Publishing S.A. AD - Department of Gastroenterology, Second Affiliated Hospital, Third Military Medical University, Chongqing, 400037, China AU - Wang, X. W. AU - Fan, C. Q. AU - Wang, L. AU - Guo, H. AU - Xie, X. AU - Zhao, G. C. AU - Zhao, X. Y. DB - Scopus DO - 10.5754/hge10443 IS - 110-111 KW - Peripancreatic abscess Transoralgastric gastroscopic M3 - Article N1 - Export Date: 10 November 2020 PY - 2011 SP - 1801-1804 ST - Transoralgastric gastroscopic debridement for peripancreatic abscess: A special case report T2 - Hepato-Gastroenterology TI - Transoralgastric gastroscopic debridement for peripancreatic abscess: A special case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-83355163492&doi=10.5754%2fhge10443&partnerID=40&md5=af458517782978a080354aad3769ad4e VL - 58 ID - 1438 ER - TY - JOUR AB - We present a 3-year-old girl with a transoral injury by a bamboo chopstick penetrating the middle skull base. The features of imaging are described and the management is discussed. The potential for injury to the cavernous sinus is emphasized, even if no there is no hemorrhage on the initial CT scan. Early intracranial infection in relation to penetrating injuries is a factor in planning treatment by craniotomy. © 2012 Elsevier Ltd. All rights reserved. AD - Department of Neurosurgery, First Hospital of Jilin University, 71 Xinmin Street, Changchun, Jilin 130021, China AU - Wang, H. F. AU - Li, W. C. AU - Xu, N. AU - Fu, S. L. DB - Scopus DO - 10.1016/j.jocn.2012.03.053 IS - 5 KW - Chopstick injury Middle Mouth Penetrating craniocerebral injury Skull base M3 - Article N1 - Cited By :8 Export Date: 10 November 2020 PY - 2013 SP - 746-748 ST - Transoral penetrating craniocerebral injury by a bamboo chopstick in a child T2 - Journal of Clinical Neuroscience TI - Transoral penetrating craniocerebral injury by a bamboo chopstick in a child UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84876692360&doi=10.1016%2fj.jocn.2012.03.053&partnerID=40&md5=7bea9f57265ba23f0463d62a3082bda6 VL - 20 ID - 1320 ER - TY - JOUR AB - Although the majority of temporary epicardial leads used during cardiac surgery are removed in the perioperative period, occasionally, the wires are cut and allowed to retract into the subcutaneous tissue. Complications arising from such retained epicardial wires are rare. We present a case of transmyocardial migration of a retained epicardial wire through the right ventricular myocardium into the pulmonary artery in a patient who had undergone coronary artery bypass graft surgery 13 years ago. We describe the presentation and successful management of this case. © 2011 Wiley Periodicals, Inc. AD - University of Toledo, 3000 Arlington Avenue, Toledo, OH 43614, United States AU - Sheikh, M. AU - Bruhl, S. R. AU - Omer, S. AU - Schwaan, T. AU - Grubb, B. AU - Cooper, C. AU - Kanjwal, Y. DB - Scopus DO - 10.1111/j.1540-8159.2011.03112.x IS - 7 KW - congestive heart failure pacing M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2012 SP - e185-e186 ST - Transmyocardial voyage of a temporary epicardial lead: An unusual long-term complication T2 - PACE - Pacing and Clinical Electrophysiology TI - Transmyocardial voyage of a temporary epicardial lead: An unusual long-term complication UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84863485688&doi=10.1111%2fj.1540-8159.2011.03112.x&partnerID=40&md5=b3c50db79a9b8fcff4efcfb525856a16 VL - 35 ID - 1366 ER - TY - JOUR AB - A surgical compress retained in the abdominal cavity following surgery is a serious problem. Here, we describe a 33-year-old female who was admitted with abdominal pain, vomiting, no passage of gas or feces, and abdominal distension for 3 days. She had a splenectomy at another medical center 4 years previously. An upright plain abdominal film revealed small bowel obstruction with marked small bowel air-fluid levels. The physical examination revealed muscular guarding and rebound tenderness in the periumbilical region. Therefore, a laparotomy was performed. A surgical compress was removed at enterotomy and the final diagnosis was gossypiboma. Because a retained surgical compress may lead to medicolegal problems, it is important to count the material used before and after a surgical procedure to reduce the risk of this problem. AD - Department of Surgery, Diyarbakir Education and Research Hospital, Op. Dr. Seref Inaloz Caddesi 21400, Diyarbakir, Turkey. akbulutsami@gmail.com AN - 19830033 AU - Akbulut, S. AU - Sevinc, M. M. AU - Basak, F. AU - Aksoy, S. AU - Cakabay, B. C2 - PMC2740219 DA - Jul 30 DO - 10.4076/1757-1626-2-7975 DP - NLM ET - 2009/10/16 LA - eng N1 - 1757-1626 Akbulut, Sami Sevinc, Mert Mahsuni Basak, Fatih Aksoy, Sefika Cakabay, Bahri Case Reports Cases J. 2009 Jul 30;2:7975. doi: 10.4076/1757-1626-2-7975. PY - 2009 SN - 1757-1626 SP - 7975 ST - Transmural migration of a surgical compress into the stomach after splenectomy: a case report T2 - Cases J TI - Transmural migration of a surgical compress into the stomach after splenectomy: a case report VL - 2 ID - 94 ER - TY - JOUR AB - The most common surgically retained foreign body is the laparotomy sponge. The clinical presentation of a retained sponge can vary from an incidental finding on plain radiograph to an intense inflammatory response with obstruction or perforation. In the case described here a patient reported abdominal pain 11 months after her hysterectomy. Although two sponge counts appeared in the operative record one laparotomy sponge had been overlooked. Apparently an inflammatory response created an abscess pocket around the sponge between the abdominal wall and the ileum resulting in perforation of the ileum. Through this opening the sponge migrated into the lumen of the small bowel, from which it was surgically removed. The patient recovered without complications. The case highlights the importance of a thorough exploration of all quadrants of the abdomen at the termination of surgical cases. AD - Department of Surgery, University of Kentucky, Lexington 40536-0293, USA. AN - 12132741 AU - Dhillon, J. S. AU - Park, A. DA - Jul DP - NLM ET - 2002/07/23 IS - 7 KW - Abdominal Pain/etiology Adult Female Foreign-Body Migration/*complications Humans Ileum/*injuries/pathology/surgery Inflammation/etiology/surgery Intestinal Perforation/*etiology/surgery Laparotomy/*instrumentation Surgical Sponges/*adverse effects LA - eng N1 - Dhillon, Jasbir S Park, Adrian Case Reports Journal Article United States Am Surg. 2002 Jul;68(7):603-5. PY - 2002 SN - 0003-1348 (Print) 0003-1348 SP - 603-5 ST - Transmural migration of a retained laparotomy sponge T2 - Am Surg TI - Transmural migration of a retained laparotomy sponge VL - 68 ID - 39 ER - TY - JOUR AB - This study investigated the role of the bone marrow-derived CD34+ cell in a milieu of osteoprogenitor cells, bone marrow plasma cell adhesion molecules, recombinant human bone morphogenetic protein (rhBMP), and a matrix of crushed cancellous allogeneic bone in the clinical regeneration of functionally useful bone in craniomandibular reconstructions. The history and current concepts of bone marrow hematopoietic stem cells and mesenchymal stem cells are reviewed as they relate to bone regeneration in large continuity defects of the mandible. Patients with 6- to 8-cm continuity defects of the mandible with retained proximal and distal segments were randomized into two groups. Group A received an in situ tissue-engineered graft containing 54 ± 38 CD34+ cells/mL along with 54 ± 38 CD44+, CD90+, and CD105+ cells/mL together with rhBMP-2 in an absorbable collagen sponge (1 mg/cm of defect) and crushed cancellous allogeneic bone. Group B received the same graft, except the CD34+ cell concentration was 1,012 ± 752 cells/mL. The results were analyzed clinically, radiographic bone density was measured in Hounsfield units (HU), and specimens were analyzed histomorphometrically. Forty patients participated (22 men and 12 women; mean age, 57 years). Eight of 20 group A patients (40%) achieved the primary endpoint of mature bone regeneration, whereas all 20 group B patients (100%) achieved the primary endpoint. CD34+ cell counts above 200/mL were associated with achievement of the primary endpoint. Bone density was lower in group A (424 ± 115 HU) than in group B (731 ± 98 HU). Group A bone showed a mean trabecular bone area of 36% ± 10%, versus 67% ± 13% for group B. The CD34+ cell functions as a central signaling cell to mesenchymal stem cells and osteoprogenitor cells in bone regeneration. The mechanism of bone marrow-supported grafts requires a complete milieu to regenerate large quantities of functionally useful bone. CD34+ cell counts in a concentration of at least 200/mL in composite grafts are directly correlated to clinically successful bone regeneration. AD - R.E. Marx AU - Marx, R. E. AU - Harrell, D. B. DB - Medline DO - 10.11607/jomi.te56 IS - 2 KW - bone morphogenetic protein 2 CD34 antigen cell surface receptor collagen ENG protein, human Hermes antigen leukocyte antigen recombinant bone morphogenetic protein 2 recombinant protein Thy 1 membrane glycoprotein transforming growth factor beta alveolar bone grafting article bone marrow cell bone regeneration controlled clinical trial controlled study female human injury male mandible mesenchymal stem cell transplantation mesenchymal stroma cell middle aged physiology randomized controlled trial surgical sponge tissue engineering LA - English M3 - Article N1 - L373333150 2014-06-26 PY - 2014 SN - 1942-4434 SP - e201-209 ST - Translational research: The CD34+ cell is crucial for large-volume bone regeneration from the milieu of bone marrow progenitor cells in craniomandibular reconstruction T2 - The International journal of oral & maxillofacial implants TI - Translational research: The CD34+ cell is crucial for large-volume bone regeneration from the milieu of bone marrow progenitor cells in craniomandibular reconstruction UR - https://www.embase.com/search/results?subaction=viewrecord&id=L373333150&from=export http://dx.doi.org/10.11607/jomi.te56 VL - 29 ID - 458 ER - TY - JOUR AB - Introduction: Oropharyngeal and Gastrointestinal (GI) perforations from BBQ brush bristles are being reported in the literature with increasing frequency. Media attention to this problem has increased awareness by the public. Most commonly, BBQ bristles lodged in the GI tract can be removed endoscopically or pass without complication. Rarely, surgical intervention is required for removal of the bristle or drainage of an associated abscess. We report a case of gastric perforation by a BBQ bristle leading to a pancreatic abscess. Case Report: A 41-year-old male presented to a regional center with epigastric pain and malaise. His medical history included: hypertension, dyslipidemia, and smoking. His surgical history included: a tonsillectomy, excision of bronchial cleft cyst, and an umbilical hernia repair. On presentation, his laboratory investigations where unremarkable aside from an elevated white blood cell count. Investigations including an abdominal X-rays and an abdominal ultrasound were unremarkable. He was initially treated with a proton pump inhibitor for presumed peptic ulcer disease. He returned to the local emergency room, no better than before. A CT scan was arranged which demonstrated a foreign body at the pylorus consistent with a BBQ bristle and a peripancreatic fluid collection (Figs. 1 & 2). A gastroscopy failed to identify the bristle. He was admitted, placed on IV antibiotics and referred to our center. Despite several days of antibiotics prior to arrival, the collection size on repeat CT scan had increased and the patient had ongoing pain. We repeated the endoscopy with a side viewing endoscope. The perforation was identified posteriorly at the pylorus. The bristle had migrated into the peripancreatic space. The perforation was can-nulated with a Jagtome. Fluoroscopy was used to confirm the position of a wire in the fluid collection (Figs. 3 & 4). Pus was drained from the collection into the stomach by placement of a 5 French pigtail catheter (Fig. 5). [Image Presented] The patient was discharged pain free the following day. The patient was asymptomatic at 6 weeks' follow-up. A repeat CT scan showed resolution of the abscess and safe migration of the bristle and stent out of the GI tract (Fig. 6) Conclusion: To our knowledge, this is the first reported transgastric endoscopic drainage of a peripancreatic abscess caused by a BBQ bristle gastric perforation. This case is a demonstration of the ever-expanding role of therapeutic endoscopy in a surgical practice. AD - R.D. Stewart, Dalhousie University Division of General Surgery, Canada AU - Stewart, R. D. AU - Ellsmere, J. DB - Embase DO - 10.1007/s00464-018-6121-4 IS - 1 KW - antibiotic agent proton pump inhibitor abdominal radiography adult bronchus case report cell migration clinical article conference abstract cyst drainage catheter dyslipidemia emergency ward endoscope epigastric pain excision fluoroscopy follow up foreign body gastrointestinal tract gastroscopy hernioplasty hospital discharge human hypertension leukocyte count malaise male medical history pancreas abscess peptic ulcer pus pylorus smoking stent stomach perforation surgery tonsillectomy ultrasound umbilical hernia x-ray computed tomography LA - English M3 - Conference Abstract N1 - L622361761 2018-06-04 PY - 2018 SN - 1432-2218 SP - S233 ST - Transgastric endoscopic drainage of a peripancreatic abscess from a bbq brush bristle gastric perforation T2 - Surgical Endoscopy and Other Interventional Techniques TI - Transgastric endoscopic drainage of a peripancreatic abscess from a bbq brush bristle gastric perforation UR - https://www.embase.com/search/results?subaction=viewrecord&id=L622361761&from=export http://dx.doi.org/10.1007/s00464-018-6121-4 VL - 32 ID - 355 ER - TY - JOUR AB - Purpose: To evaluate the efficacy of transepithelial collagen crosslinking (CXL) in patients with bilateral progressive keratoconus. Setting: Outpatient ophthalmic clinic. Design: Cohort study. Methods: Patients with a history of bilateral progressive keratoconus were recruited. The worst eye was treated with transepithelial CXL, while the fellow eye was left untreated as a control. Transepithelial CXL was performed by applying an enhanced riboflavin solution (riboflavin 0.1%, dextrane T500 with trometamol [Tris-hydroxymethyl aminomethane] and EDTA [ethylenediaminetetraacetic] sodium salt) on the intact corneal epithelium for 30 minutes before irradiation with ultraviolet A (370 nm at 3 mW/cm 2) for 30 minutes. Follow-up was 18 months in all eyes. Results: The study enrolled 20 patients. Transient hyperemia and mild foreign-body sensation occurred in 8 eyes (40%) after treatment; both resolved after 24 hours. In treated eyes, there were statistically significant improvements in uncorrected and corrected visual acuity and topography-derived keratometry, cone apex power, and higher-order aberrations (P<.05). In untreated control eyes, there was a general trend toward worsening of these parameters. No complications were reported. Conclusions: Transepithelial CXL treatment appeared to halt keratoconus progression, with a statistically significant improvement in visual and topographic parameters. The treatment was safe and well tolerated. Its noninvasive nature makes it potentially useful in cases in which epithelial debridement is ideally avoided, such as pediatric cases, uncooperative patients, and thin corneas with thicknesses nearing 380 μm. Financial Disclosure: No author has a financial or proprietary interest in any material or method mentioned. © 2011 ASCRS and ESCRS Published by Elsevier Inc. AD - Casa di Cura di Stefano-Velona, Catania, Italy Kings College, University of London, London, United Kingdom AU - Filippello, M. AU - Stagni, E. AU - O'Brart, D. DB - Scopus DO - 10.1016/j.jcrs.2011.08.030 IS - 2 M3 - Article N1 - Cited By :155 Export Date: 10 November 2020 PY - 2012 SP - 283-291 ST - Transepithelial corneal collagen crosslinking: Bilateral study T2 - Journal of Cataract and Refractive Surgery TI - Transepithelial corneal collagen crosslinking: Bilateral study UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84857049704&doi=10.1016%2fj.jcrs.2011.08.030&partnerID=40&md5=0c2cea238363ff22231b28d5d1b44efe VL - 38 ID - 1385 ER - TY - JOUR AB - Purpose: To evaluate the effectiveness and safety of transepithelial corneal collagen crosslinking (CXL) in children with keratoconus and the refractive changes induced by this treatment. Setting: Ophthalmology Department, Ain-Shams University Hospitals, Cairo, Egypt. Design: Prospective comparative case series. Methods: Patients younger than 18 years with bilateral keratoconus had transepithelial CXL with the use of transepithelial riboflavin. The other eye was used as a control and was treated conservatively. The uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), and corneal tomography at 12 months were the main outcome measures. Results: The mean age of the 22 patients (22 eyes) was 15.7 years ± 2.1 (SD). After transepithelial CXL, the improvement in the mean UDVA was statistically significant (from 0.95 ± 0.34 logMAR to 0.68 ± 0.45 logMAR) (P<.05). No eye lost lines of preoperative UDVA; 1 eye lost 1 line of preoperative CDVA. There was no improvement in the control group in UDVA or CDVA (P>.05). The mean simulated keratometry (K) decreased by a mean of 2.03 diopters (D), with mean flattening of the apical K by 2.20 D; both results were statistically significant (P<.05). In the control group, the simulated K increased by a mean of 0.59 D (P>.05), with mean steepening of the apical K by 2.9 D (P<.05). No significant changes occurred in the endothelial cell count in either group. Conclusion: Preliminary results of transepithelial CXL in children with keratoconus were encouraging, with no evidence of progression of keratoconus over 12 months. Financial Disclosure: The author has no financial or proprietary interest in any material or method mentioned. © 2013 ASCRS and ESCRS. AD - A.G. Salman, Ophthalmology Department, Ain Shams University, Cairo, Egypt AU - Salman, A. G. DB - Embase Medline DO - 10.1016/j.jcrs.2013.03.017 IS - 8 KW - riboflavin adolescent adult article cell count childhood disease clinical article comparative study conservative treatment controlled clinical trial controlled study corneal collagen crosslinking corneal pachymetry disease course Egypt endothelium cell female foreign body human hyperemia keratoconus keratometry male outcome assessment preoperative period priority journal prospective study radiological procedures skin defect therapy effect tomography ultraviolet irradiation university hospital visual acuity LA - English M3 - Article N1 - L52642125 2013-06-24 2013-08-09 PY - 2013 SN - 0886-3350 1873-4502 SP - 1164-1170 ST - Transepithelial corneal collagen crosslinking for progressive keratoconus in a pediatric age group T2 - Journal of Cataract and Refractive Surgery TI - Transepithelial corneal collagen crosslinking for progressive keratoconus in a pediatric age group UR - https://www.embase.com/search/results?subaction=viewrecord&id=L52642125&from=export http://dx.doi.org/10.1016/j.jcrs.2013.03.017 VL - 39 ID - 477 ER - TY - JOUR AB - PURPOSE: To determine the efficacy of a novel technique for a 'transconjunctival 20-gauge vitrectomy' (T20V). METHODS: In total, 12 eyes of 12 consecutive patients were included in a prospective study. The mean age was 58 years (range: 38-74 years); 4 patients were male and 8 were female. The T20V was indicated when short-duration vitrectomy was envisioned: macular surgery for macular hole and epiretinal membrane therapy, moderate vitreous hemorrhage due to retina vein occlusions or diabetic retinopathy, or neurotomy for central retinal vein occlusion. RESULTS: The average time for each procedure was 35 +/- 30 min (SD). The preoperative visual acuity ranged from 20/200 to hand motions, while postoperative vision was between 20/30 and counting fingers. The average intraocular pressure changed from 16.1 +/- 5.6 mm Hg preoperatively to 15.8 +/- 8.1 mm Hg in the first postoperative day, and 17.8 +/- 9.4 mm Hg 1 week after surgery - these differences were not statistically significant (p > 0.05). Subjective postoperative pain and foreign body sensation at postoperative day 1 and week 1 were mild to moderate. The chemosis observed 1 h after surgery was minimal, and disappeared quickly during the 1-week follow-up. CONCLUSION: The T20V is suitable to perform short-duration vitrectomy surgery, and has a low rate of ocular complications, similar to 25- or 23-gauge sutureless vitrectomy systems. AD - Retina Department, Hospital Regional Sao Jose, CEPON, Florianopolis, Brazil. AN - 18849631 AU - Aguni, J. S. AU - Meyer, C. H. AU - Rodrigues, E. B. DO - 10.1159/000161877 DP - NLM ET - 2008/10/14 IS - 1 KW - Adult Aged Conjunctiva/*surgery Diabetic Retinopathy/complications Epiretinal Membrane/physiopathology/surgery Female Follow-Up Studies Humans Intraocular Pressure Male Middle Aged Pilot Projects Postoperative Period Prospective Studies Retinal Perforations/physiopathology/surgery Retinal Vein Occlusion/complications/surgery Sclera/surgery Time Factors Treatment Outcome Visual Acuity Vitrectomy/adverse effects/*methods Vitreous Hemorrhage/etiology/physiopathology/surgery LA - eng N1 - 1423-0267 Aguni, Jonathan Seiji Meyer, Carsten H Rodrigues, Eduardo B Journal Article Switzerland Ophthalmologica. 2009;223(1):12-6. doi: 10.1159/000161877. Epub 2008 Oct 13. PY - 2009 SN - 0030-3755 SP - 12-6 ST - Transconjunctival 20-gauge vitrectomy: a pilot study T2 - Ophthalmologica TI - Transconjunctival 20-gauge vitrectomy: a pilot study VL - 223 ID - 84 ER - TY - JOUR AB - Colonic perforation is an extremely rare complication following ventriculoperitoneal (VP) shunting. Laparotomy to repair the perforation site is usually required for patients with peritonitis. Here we report colonic perforation due to VP shunt in a 4-year-old girl, presenting with a distal catheter protruding out of the anus as well as symptoms and signs of peritonitis. The distal catheter was removed and the perforation site was repaired successfully via the anus. Postoperative course was uneventful. Trans-anal repair of the colonic perforation after removal of the distal shunt may be considered an alternative choice for managing this kind of complication. © 2010 Formosan Medical Association & Elsevier. AD - Department of Pediatrics, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan Department of Surgery, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan AU - Chiang, L. L. AU - Kuo, M. F. AU - Fan, B. J. AU - Hsu, W. M. DB - Scopus DO - 10.1016/S0929-6646(10)60079-4 IS - 6 KW - bowel perforation transanal repair ventriculoperitoneal shunt M3 - Article N1 - Cited By :18 Export Date: 10 November 2020 PY - 2010 SP - 472-475 ST - Transanal Repair of Colonic Perforation due to Ventriculoperitoneal Shunt-Case Report and Review of the Literature T2 - Journal of the Formosan Medical Association TI - Transanal Repair of Colonic Perforation due to Ventriculoperitoneal Shunt-Case Report and Review of the Literature UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77953676535&doi=10.1016%2fS0929-6646%2810%2960079-4&partnerID=40&md5=8908415ad3ea0153a59290dd85cd6c43 VL - 109 ID - 1456 ER - TY - JOUR AB - Retained rectal foreign bodies are increasingly reported in current clinical practice, and there is no clear consensus in the literature as to whether transanal extraction should be performed in the emergency or in the operating room. A 47-year-old presented to the hospital for a retained drinking glass in the rectum that was broken after an attempt at self-extraction. Physical examination showed no evidence of abdominal guarding nor bleeding from the rectum; abdominal and pelvic X-rays confirmed the presence of a broken glass, 8×6 cm in size and no signs of perforation. Initial anoscopy performed in the emergency room confirmed the partial fracture of the glass. The patient was transferred to the operating room and transanal extraction was carried out under general anaesthesia without complications. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. AD - Universita Degli Studi di Milano, Surgery, Milano, Italy IRCCS Policlinico San Donato, Surgery, San Donato Milanese, Lombardia, Italy Universita Degli Studi di Milano, Biomedical Sciences for Health, Milano, Italy AU - Lazzari, V. AU - Siboni, S. AU - Asti, E. AU - Bonavina, L. C7 - 220268 DB - Scopus DO - 10.1136/bcr-2017-220268 KW - Anxiety disorders (including OCD and PTSD) Endoscopy Gastrointestinal surgery General surgery Sexual and gender disorders M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2017 ST - Transanal removal of a broken drinking glass self-inserted and retained in the rectum T2 - BMJ Case Reports TI - Transanal removal of a broken drinking glass self-inserted and retained in the rectum UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85020204814&doi=10.1136%2fbcr-2017-220268&partnerID=40&md5=654b2eb0d6f46c300a0f51229fd39623 VL - 2017 ID - 1156 ER - TY - JOUR AB - Aim: Persistent or recurrent wheezing is a common indication for flexible bronchoscopy, as anatomic and infectious or inflammatory changes are highly prevalent. We sought to evaluate the prevalence of anatomic, infectious, and inflammatory disease in a cohort of children undergoing flexible bronchoscopy for wheezing or poorly controlled asthma. Methods: We retrospectively reviewed all children <18 years old who underwent flexible bronchoscopy at our center from October 29, 2012-December 31, 2016 for the primary or secondary indication of wheezing (persistent, frequently recurring, or atypical) or poorly controlled asthma. Results: A total of 101 procedures were identified in 94 patients, aged 3 months to 18 years. Potential anatomic causes for wheezing identified in 45.7% of patients and inflammatory changes in 49.5% of procedures. This included the identification of a laryngeal cleft in 17% for which half required medical or surgical management. Tracheobronchomalacia was the most commonly identified anatomic lesion. Thirty children from this cohort had poorly controlled asthma. Among this subgroup, 54% had increased neutrophils on BAL and 30% had an anatomic contributor to wheezing, including one with a laryngeal cleft. Based on findings from flexible bronchoscopy, management changes made in 63.8% of patients. This included medication changes in 54 and surgical intervention in 9. Discussion: We conclude that transnasal flexible bronchoscopy has high yield in children with recurrent, persistent, or atypical wheezing and those with poorly controlled asthma. Laryngeal cleft has a reasonably high prevalence that warrants specific evaluation in this population. © 2017 Wiley Periodicals, Inc. AD - Mayo Clinic Children's Center, Division of Pediatric Pulmonology, Rochester, MN, United States Mayo Clinic Minnesota, Department of Otorhinolaryngology-Head and Neck Surgery, Rochester, MN, United States AU - Boesch, R. P. AU - Baughn, J. M. AU - Cofer, S. A. AU - Balakrishnan, K. DB - Scopus DO - 10.1002/ppul.23829 IS - 3 KW - asthma flexible bronchoscopy laryngeal cleft wheezing yield M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2018 SP - 310-315 ST - Trans-nasal flexible bronchoscopy in wheezing children: Diagnostic yield, impact on therapy, and prevalence of laryngeal cleft T2 - Pediatric Pulmonology TI - Trans-nasal flexible bronchoscopy in wheezing children: Diagnostic yield, impact on therapy, and prevalence of laryngeal cleft UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85029408140&doi=10.1002%2fppul.23829&partnerID=40&md5=52f27768056ff407480bc403cb7d4e32 VL - 53 ID - 1088 ER - TY - JOUR AB - BACKGROUND AND PURPOSE: Fomites are increasingly being recognised as a source of hospital-acquired infection. We have therefore assessed tourniquets and exsanguinators for the presence of bacterial pathogens in 1 elective and 2 trauma orthopedic hospitals. MATERIAL AND METHODS: Swabs were taken prior to and after decontaminating these devices with 1 of 3 different cleaning modalities. These were then assessed for colony counts and organisms identified. RESULTS: Bacteria commonly implicated in surgical site infections such as coagulase-negative staphylococci, Staphylococcus aureus and Proteus spp. were prevalent. We also found a resistant strain of Acinetobacter and Candida. Exsanguinators were the most heavily contaminated devices, and colony counts in the trauma hospitals were up to 400% higher than in the elective hospital. Alcohol- and non-alcohol-based sterile wipes were both highly effective in decontaminating the devices. INTERPRETATION: Infectious organisms reside on the tourniquets and exsanguinators presently used in the orthopedic theater. These fomites may possibly be a source of surgical site infection. We have demonstrated a simple and effective means of decontaminating these devices between cases. AD - Cappagh National, Orthopaedic Hospital, Dublin, Ireland. AN - 105519448. Language: English. Entry Date: 20090612. Revision Date: 20200708. Publication Type: Journal Article AU - Brennan, S. A. AU - Walls, R. J. AU - Smyth, E. AU - Al Mulla, T. AU - O'Byrne, J. M. DB - ccm DO - 10.3109/17453670902930016 DP - EBSCOhost IS - 2 KW - Bacterial Infections -- Risk Factors Operating Rooms Orthopedic Surgery -- Adverse Effects Bacterial Colonization Candidiasis Cleaning Compounds Descriptive Statistics Fisher's Exact Test Gram-Positive Bacteria Microbial Culture and Sensitivity Tests Proteus Staphylococcus Aureus Sterilization and Disinfection -- Methods Surgical Instruments -- Adverse Effects Surgical Wound Infection -- Risk Factors Tourniquets -- Adverse Effects Human N1 - research; tables/charts. Journal Subset: Allied Health; Biomedical; Continental Europe; Europe; Peer Reviewed. NLM UID: 101231512. PMID: NLM19404812. PY - 2009 SN - 1745-3674 SP - 251-255 ST - Tourniquets and exsanguinators: a potential source of infection in the orthopedic operating theater? T2 - Acta Orthopaedica TI - Tourniquets and exsanguinators: a potential source of infection in the orthopedic operating theater? UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105519448&site=ehost-live&scope=site VL - 80 ID - 782 ER - TY - JOUR AB - Introduction: Foreign body ingestion is a common occurrence in both adults and in children. It is usually a benign occurrence with 75.6% of all FB ingestions passing through the GI tract spontaneously. Rarely, does the foreign body perforate the intestinal wall (0.73%). Perforation is difficult to diagnose as history, symptoms, laboratory and imaging tests are often vague and non-specific Case Presentation: We present a case of a 55 year old Hispanic woman with a 3 day history of abdominal pain associated with anorexia, nausea and one episode of vomiting. Physical examination demonstrated tachycardia at 110 beats per minute, and an obese abdomen that was diffusely tender, with rebound tenderness in the right lower quadrant. Routine laboratory studies revealed an elevated white blood cell count and alkaline phosphatase level. CT of the abdomen demonstrated mural thickening of a small segment of small bowel. No intraperitoneal free air or fluid was seen. After 48 hours, laboratory values returned to normal but right lower quadrant tenderness persisted. Diagnostic laparoscopy was performed and a foreign body was seen protruding through the bowel wall 100cm proximal to the ileal cecal valve. A 3cm fragment of chicken bone was removed with laparoscopic graspers and the perforation was primarily repaired. Postoperatively, the patient improved significantly and was discharged home on post operative day 1. Discussion: Bowel perforation by foreign body can be difficult to diagnose as the most common clinical presentation is of diffuse abdominal pain (67%). Risk factors for foreign body ingestion include orthodontic appliances (75%), mental illness and alcoholism. Sensitivity of CT is low, detecting only 10% of all foreign body intestinal perforations. 90% of foreign body perforations are diagnosed during laparotomy, with most pre-operative diagnoses being acute appendicitis, acute diverticulitis or acute abdomen of unknown origin. The majority of foreign body perforations are repaired with laparotomy and resection of the injured bowel with or without colostomy. We demonstrated that laparoscopic removal of the foreign body with primary repair can result in a satisfactory outcome with minimal hospital stay. AD - F. Herman, St. Francis Medical Center, Seton Hall University, School of Graduate Medical Education, United States AU - Herman, F. AU - Patel, N. AU - Yung, M. AU - Christian, D. DB - Embase DO - 10.1007/s00464-010-0972-7 IS - 1 KW - alkaline phosphatase perforation jejunum society surgeon human foreign body ingestion laboratory intestine abdomen intestine perforation laparotomy diagnosis abdominal pain intraperitoneal drug administration anorexia female alcoholism tachycardia Hispanic leukocyte count diverticulitis small intestine acute abdomen liquid child physical examination risk factor vomiting imaging patient bone nausea chicken laparoscopy orthodontic device mental disease hospitalization acute appendicitis surgery colostomy intestine wall adult LA - English M3 - Conference Abstract N1 - L71511505 2014-07-01 PY - 2010 SN - 0930-2794 SP - S368-S369 ST - Total laparoscopic repair of foreign body perforation of jejunum T2 - Surgical Endoscopy and Other Interventional Techniques TI - Total laparoscopic repair of foreign body perforation of jejunum UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71511505&from=export http://dx.doi.org/10.1007/s00464-010-0972-7 VL - 24 ID - 571 ER - TY - JOUR AB - A 66-year-old male with a history of hypertension, back pain, diverticulosis and anal fistula presents with acute onset syncopal episodes, worsening back pain, and altered mental status. The patient exhibited considerable leukocytosis but was hemodynamically stable. CT imaging of the head revealed a gas pattern in the posterior fossa and velum interpositum. CT imaging of the abdomen and pelvis revealed a needle-like foreign body traversing the left sacrum to the sigmoid colon. A lumbar puncture revealed meningitis. Flexible sigmoidoscopies were performed without successful visualization of the foreign body. An explorative laparoscopy was successfully performed, enabling retrieval of what was determined to be a wooden toothpick. The patient remained hemodynamically stable with persistent altered mental status and was eventually discharged after completion of antibiotics on day 47 of hospitalization. This case illustrates a rare complication of ingesting a sharp foreign body that was identified by CT of the brain and abdomen/pelvis with successful surgical repair. © 2016 The Authors AD - Eastern Virginia Medical School, 700 W Olney Rd, Norfolk, VA 23510, United States AU - Zhou, Q. AU - Singh, N. AU - Monteforte, B. DB - Scopus DO - 10.1016/j.radcr.2016.10.011 IS - 2 KW - Foreign object Ingestion Meningitis Perforation M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2017 SP - 265-268 ST - Toothpick meningitis T2 - Radiology Case Reports TI - Toothpick meningitis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85012938493&doi=10.1016%2fj.radcr.2016.10.011&partnerID=40&md5=7a3d2ffb8e518c244da0923f21fd1e5c VL - 12 ID - 1133 ER - TY - JOUR AB - In childhood, almost all swallowed objects that successfully navigate the esophagus pass through the gut without complications. In a 15-year-old male adolescent with the initial working diagnosis of acalculous cholecystitis, computed tomography revealed a thickened wall of the second duodenal portion, some infiltration of the periduodenal tissue, and a hyperdense needle-shape structure probably passing through the duodenal wall. Endoscopy revealed a wooden toothpick perforating the duodenum that was carefully retracted. An uneventful recovery followed the endoscopic removal of the foreign body. A computer-based search of the literature to examine the injuries caused by ingested toothpicks since 1960 found only 4 reports in 5 children. © 2010 by Lippincott Williams & Wilkins. AD - Division of Pediatrics, Ospedale Mendrisio, Mendrisio, and Bellinzona, University of Bern, Bern, Switzerland Divisions of Gastroenterology, Ospedale Mendrisio, Mendrisio, Switzerland Divisions of Diagnostic Imaging, Ospedale Mendrisio, Mendrisio, Switzerland Divisions of and Surgery, Ospedale Mendrisio, Mendrisio, Switzerland AU - Ragazzi, M. AU - Delcò, F. AU - Rodoni-Cassis, P. AU - Brenna, M. AU - Lavanchy, L. AU - Bianchetti, M. G. DB - Scopus DO - 10.1097/PEC.0b013e3181e5bf85 IS - 7 KW - duodenal perforation foreign bodies ingestion toothpick M3 - Article N1 - Cited By :14 Export Date: 10 November 2020 PY - 2010 SP - 506-507 ST - Toothpick ingestion causing duodenal perforation T2 - Pediatric Emergency Care TI - Toothpick ingestion causing duodenal perforation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77954872518&doi=10.1097%2fPEC.0b013e3181e5bf85&partnerID=40&md5=d96395dadb954697d3f5076510636adc VL - 26 ID - 1475 ER - TY - JOUR AD - Cape Cod Hospital, 27 Park Street, Hyannis, MA 02601, USA; cking@capecodhealth.org AN - 105605847. Language: English. Entry Date: 20090206. Revision Date: 20150711. Publication Type: Journal Article AU - King, C. A. DB - ccm DP - EBSCOhost IS - 4 KW - Foreign Bodies -- Prevention and Control Patient Safety Perioperative Care Surgical Count Procedure -- Standards Foreign Bodies -- Risk Factors Negligence -- Legislation and Jurisprudence Perioperative Nursing Quality Improvement N1 - diagnostic images; tables/charts. Journal Subset: Core Nursing; Nursing; USA. NLM UID: 101276516. PY - 2008 SN - 1556-7931 SP - 395-400 ST - To count or not to count: a surgical misadventure T2 - Perioperative Nursing Clinics TI - To count or not to count: a surgical misadventure UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105605847&site=ehost-live&scope=site VL - 3 ID - 848 ER - TY - JOUR AB - A transverse transcondylar osteotomy of the distal femur was fixed with an axially placed absorbable fracture fixation screw made of polyglycolide (PGA) in 25 rabbits. Changes at the tissue-implant interface accompanying degradation of the screw were examined histologically, histomorphometrically, and microradiographically seven, 20, 40, 80, and 250 days after implantation. At seven days postimplantation, a layer of fibroblasts was seen surrounding the implant, and new bone formation was discernible in the host tissues adjacent to this membranous structure. At 20 days postimplantation, the geometry of the screw was still intact and the tissue-implant boundary was distinct. The first signs of invasion of vascular granulation tissue into the implant were observed 40 days after implantation, at which time the osteotomies were united. The apparent walling-off response by formation of new trabecular bone outlining the PGA profile continued, with the greatest mean trabecular bone volume fraction at the interface, 23.9%, measured at 40 days. A significant decrease in the new bone volume occurred between 40 and 80 days postimplantation. The intensity of the foreign-body reaction seen was histologically moderate. The giant cell count was highest at 80 days postimplantation, when the migratory activity of phagocytic cells had transported intracellular particulate polymeric debris 400-800 μm away from the original tissue-implant boundary. At 250 days postimplantation, no birefringent polymeric material could be seen in the specimens. No contraindications for the clinical application of PGA implants emerged in this study. AD - Tiirasaarentie 11 A 3, SF-00200 Helsinki, Finland AU - Bostman, O. M. AU - Paivarinta, U. AU - Partio, E. AU - Manninen, M. AU - Vasenius, J. AU - Majola, A. AU - Rokkanen, P. DB - Scopus IS - 285 M3 - Article N1 - Cited By :37 Export Date: 10 November 2020 PY - 1992 SP - 263-272 ST - The tissue-implant interface during degradation of absorbable polyglycolide fracture fixation screws in the rabbit femur T2 - Clinical Orthopaedics and Related Research TI - The tissue-implant interface during degradation of absorbable polyglycolide fracture fixation screws in the rabbit femur UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026457540&partnerID=40&md5=7810fe93c00ad979151d7c395189ebc3 ID - 1734 ER - TY - JOUR AB - In vitro multiplication of isolated autologous chondrocytes is required to obtain an adequate number of cells to generate neo-cartilage, but is known to induce cell-dedifferentiation. The aim of this study was to investigate whether multiplied chondrocytes can be used to generate neo-cartilage in vivo. Adult bovine articular chondrocytes, of various differentiation stages, were suspended in alginate at densities of 10 or 50 million/ml, either directly after isolation (P0) or after multiplication in monolayer for one (P1) or three passages (P3). Alginate with cells was seeded in demineralized bovine bone matrix (DBM) or a fleece of polylactic/polyglycolic acid (E210) and implanted in nude mice for 8 weeks. The newly formed tissue was evaluated by Alcian Blue and immunohistochemical staining for collagen type-II and type-I. Structural homogeneity of the tissue, composed of freshly isolated as well as serially passaged cells, was found to be enhanced by high-density seeding (50 million/ml) and the use of E210 as a carrier. The percentage of collagen type-II positive staining P3-cells was generally higher when E210 was used as a carrier. Furthermore, seeding P3-chondrocytes at the highest density (50 million/ml) enhanced collagen type-II expression. This study shows promising possibilities to generate structurally regular neo-cartilage using multiplied chondrocytes in alginate in combination with a fleece of polylactic/polyglycolic acid. Copyright (C) 2000 Elsevier Science B.V. In vitro multiplication of isolated autologous chondrocytes is required to obtain an adequate number of cells to generate neo-cartilage, but is known to induce cell-dedifferentiation. The aim of this study was to investigate whether multiplied chondrocytes can be used to generate neo-cartilage in vivo. Adult bovine articular chondrocytes, of various differentiation stages, were suspended in alginate at densities of 10 or 50 million/ml, either directly after isolation (P0) or after multiplication in monolayer for one (P1) or three passages (P3). Alginate with cells was seeded in demineralized bovine bone matrix (DBM) or a fleece of polylactic/polyglycolic acid (E210) and implanted in nude mice for 8 weeks. The newly formed tissue was evaluated by Alcian Blue and immunohistochemical staining for collagen type-II and type-I. Structural homogeneity of the tissue, composed of freshly isolated as well as serially passaged cells, was found to be enhanced by high-density seeding (50 million/ml) and the use of E210 as a carrier. The percentage of collagen type-II positive staining P3-cells was generally higher when E210 was used as a carrier. Furthermore, seeding P3-chondrocytes at the highest density (50 million/ml) enhanced collagen type-II expression. This study shows promising possibilities to generate structurally regular neo-cartilage using multiplied chondrocytes in alginate in combination with a fleece of polylactic/polyglycolic acid. AD - Department of Orthopaedics, Hd. Neck Surg., Erasmus Univ. M., Rotterdam, Netherlands Department of Otorhinolaryngology, Hd. Neck Surg., Erasmus Univ. PO B., Medical Center, Netherlands Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilians University, Germany AU - Marijnissen, W. J. C. M. AU - Van Osch, G. J. V. M. AU - Aigner, J. AU - Verwoerd-Verhoef, H. L. AU - Verhaar, J. A. N. DB - Scopus DO - 10.1016/S0142-9612(99)00218-5 IS - 6 KW - Alginate Biomaterials Cell density Cultured chondrocytes Nude mice M3 - Article N1 - Cited By :93 Export Date: 10 November 2020 PY - 2000 SP - 571-580 ST - Tissue-engineered cartilage using serially passaged articular chondrocytes. Chondrocytes in alginate, combined in vivo with a synthetic (E210) or biologic biodegradable carrier (DBM) T2 - Biomaterials TI - Tissue-engineered cartilage using serially passaged articular chondrocytes. Chondrocytes in alginate, combined in vivo with a synthetic (E210) or biologic biodegradable carrier (DBM) UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033970511&doi=10.1016%2fS0142-9612%2899%2900218-5&partnerID=40&md5=ac60059f1ac7d097cc5cd85fa186f4ca VL - 21 ID - 1677 ER - TY - JOUR AB - We compared the tissue response to a nonabsorbable monofilamented suture made of expanded polytetrafluoroethylene (ePTFE), which has recently been introduced for use in plastic surgery, with the response to 10 other commercially available absorbable sutures and nonabsorbable monofilamented and multifilamented sutures. The sutures were used to secure a patch of ePTFE implanted in the dorsum of adult New Zealand White rabbits. At 30, 60, and 120 days after implantation, the tissue response to the sutures was assessed with respect to the number of foreign-body giant cells present, the thickness of the fibrous capsule that developed, and the general inflammatory response (n = 4 for each suture for each time period). Analysis of variance revealed that specific suture type was significantly associated with foreign-body giant cell count and fibrous capsule thickness. Tevdek had a significantly higher value for mean number of foreign-body giant cells. Silk and Tevdek had significantly thicker fibrous capsules, and ePTFE suture had a significantly thinner capsule. Absorbable sutures and nonabsorbable multifilamented sutures evoked a more extensive tissue response than monofilamented sutures; the differences between nonabsorbable monofilamented and nonabsorbable multifilamented sutures were significant for capsule thickness. In general, suture made of ePTFE produced a minimal tissue response. It should be a good choice for use in facial plastic surgery, in which excellent functional and aesthetic results are critical. AD - Div. Otolaryngol. - Hd. Neck Surg., Department of Surgery, Albany Medical Center, Albany, NY, United States Div. Otolaryngol. - Hd. Neck S., Department of Surgery, Albany Medical College, 47 New Scotland Avenue, Albany, NY 12208, United States AU - Setzen, G. AU - Williams Iii, E. F. DB - Scopus DO - 10.1097/00006534-199712000-00023 IS - 7 M3 - Article N1 - Cited By :90 Export Date: 10 November 2020 PY - 1997 SP - 1788-1795 ST - Tissue response to suture materials implanted subcutaneously in a rabbit model T2 - Plastic and Reconstructive Surgery TI - Tissue response to suture materials implanted subcutaneously in a rabbit model UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030657835&doi=10.1097%2f00006534-199712000-00023&partnerID=40&md5=0bc04de40e47b767fb9910017d8c8fc7 VL - 100 ID - 1708 ER - TY - JOUR AB - An in vivo study was conducted to assess the sensitivity of fibrous capsule thickness and macrophage density to polymer fiber diameter. Single polypropylene fibers of diameters ranging from 2.1 to 26.7 μm were implanted in the subcutaneous dorsum of Sprague-Dawley rats. Results at 5 weeks demonstrated reduced fibrous capsule thickness for small fibers. Capsule thickness was 0.6 (± 1.8) μm, 11.7 (± 12.0) μm, 20.3 (± 11.6) μm, and 25.5 (μ 10.0) μm for fibers in the ranges of 2.1 to 5.9, 6.5 to 10.6, 11.1 to 15.8, and 16.7 to 26.7 μm, respectively. Fibers very near to blood vessels had smaller capsules than did those with local vasculature further away. The macrophage density in tissue with fiber diameters 2.1 to 5.9 μm (23.03 ± 8.67%) was comparable to that of unoperated contralateral control skin (18.72 ± 10.06%). For fibers with diameters in the ranges of 6.5 to 10.6, 11.1 to 15.8, and 16.7 to 26.7 μm, macrophage densities were 33.90 ± 13.08%, 34.40 ± 15.77%, and 41.68 ± 13.98%, respectively, all of which were significantly larger (p < 0.002) than that for the control. The reduced fibrous capsule thickness and macrophage density for small fibers (< 6 μm) compared with large fibers could be due to the reduced cell-material contact surface area or to a curvature threshold effect that triggers cell signaling. A next step will be to extend the analysis to meshes to evaluate fiber- spacing effects on small-fiber biomaterials. (C) 2000 John Wiley and Sons, Inc. An in vivo study was conducted to assess the sensitivity of fibrous capsule thickness and macrophage density to polymer fiber diameter. Single polypropylene fibers of diameters ranging from 2.1 to 26.7 μm were implanted in the subcutaneous dorsum of Sprague-Dawley rats. Results at 5 weeks demonstrated reduced fibrous capsule thickness for small fibers. Capsule thickness was 0.6 (±1.8) μm, 11.7 (±12.0) μm, 20.3 (±11.6) μm, and 25.5 (±10.0) μm for fibers in the ranges of 2.1 to 5.9, 6.5 to 10.6, 11.1 to 15.8, and 16.7 to 26.7 μm, respectively. Fibers very near to blood vessels had smaller capsules than did those with local vasculature further away. The macrophage density in tissue with fiber diameters 2.1 to 5.9 μm (23.03 ± 8.67%) was comparable to that of unoperated contralateral control skin (18.72 ± 10.06%). For fibers with diameters in the ranges of 6.5 to 10.6, 11.1 to 15.8, and 16.7 to 26.7 μm, macrophage densities were 33.90 ± 13.08%, 34.40 ± 15.77%, and 41.68 ± 13.98%, respectively, all of which were significantly larger (p < 0.002) than that for the control. The reduced fibrous capsule thickness and macrophage density for small fibers (<6 μm) compared with large fibers could be due to the reduced cell-material contact surface area or to a curvature threshold effect that triggers cell signaling. A next step will be extend the analysis to meshes to evaluate fiber-spacing effects on small-fiber biomaterials. AD - Department of Bioengineering, University of Washington, Seattle, WA 98195, United States AU - Sanders, J. E. AU - Stiles, C. E. AU - Hayes, C. L. DB - Scopus DO - 10.1002/1097-4636(200010)52:1<231::AID-JBM29>3.0.CO;2-E IS - 1 KW - Fibro-porous biomaterials Fibrous encapsulation Macrophage Microfibers Polypropylene M3 - Article N1 - Cited By :131 Export Date: 10 November 2020 PY - 2000 SP - 231-237 ST - Tissue response to single-polymer fibers of varying diameters: Evaluation of fibrous encapsulation and macrophage density T2 - Journal of Biomedical Materials Research TI - Tissue response to single-polymer fibers of varying diameters: Evaluation of fibrous encapsulation and macrophage density UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034256006&doi=10.1002%2f1097-4636%28200010%2952%3a1%3c231%3a%3aAID-JBM29%3e3.0.CO%3b2-E&partnerID=40&md5=22150ee5d12a131a1e7d2c4337e4daeb VL - 52 ID - 1674 ER - TY - JOUR AB - Hydrogels are three-dimensional networks of crosslinked hydrophilic polymers widely used for protein delivery and tissue engineering. To be eligible for in vivo applications, the hydrogels should not evoke an adverse tissue response. In this study the angiogenic and inflammatory responses in vivo after implantation of photopolymerized thermosensitive poly(hydroxypropyl methacrylamide lactate)-poly(ethyl copolymer hydrogels are investigated. Hydrogels consisting of polymers with different crosslink densities were subcutaneously implanted in Balb/c mice and histological evaluation of the tissue response was performed. The implants showed an acute and localized inflammatory reaction upon implantation, mainly characterized by a strong infiltration of granulocytes. The acute inflammatory reaction was followed by a milder chronic inflammation which was characterized by infiltration of macrophages and persistent but decreasing levels of granulocytes. The number of macrophages and blood vessels was associated with the biodegradation and resorption of the biomaterial and increased in time as the degradation of the materials progressed. The observed degradation rates in vivo correlated well with previously observed in vitro degradation rates, which suggests that hydrolysis is the main mechanism governing the degradation. © 2011 Wiley Periodicals, Inc. AD - Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, P.O. Box 80082, 3508 TB Utrecht, Netherlands Department of Chemical Sciences, Camerino University, via S. Agostino 1, 62032, Camerino (MC), Italy Department of Pathology and Medical Biology, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, Netherlands AU - Censi, R. AU - Van Putten, S. AU - Vermonden, T. AU - Di Martino, P. AU - Van Nostrum, C. F. AU - Harmsen, M. C. AU - Bank, R. A. AU - Hennink, W. E. DB - Scopus DO - 10.1002/jbm.a.33048 IS - 3 KW - angiogenesis biodegradation granulocytes macrophages photopolymerized thermosensitive hydrogels M3 - Review N1 - Cited By :20 Export Date: 10 November 2020 PY - 2011 SP - 219-229 ST - The tissue response to photopolymerized PEG-p(HPMAm-lactate)-based hydrogels T2 - Journal of Biomedical Materials Research - Part A TI - The tissue response to photopolymerized PEG-p(HPMAm-lactate)-based hydrogels UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79955025746&doi=10.1002%2fjbm.a.33048&partnerID=40&md5=db3d609ca16c9296e81dc8ef9146accb VL - 97 A ID - 1419 ER - TY - JOUR AB - During follow-up periods of 6, 12, 24 and 48 weeks, the tissue response to a braided poly-L-lactide (PLLA) implant, 3.2 mm in diameter, was investigated in the reconstruction of experimental anterior cruciate ligament (ACL) ruptures in 32 sheep. In 16 sheep the cut ACL was removed and reconstructed with the fascia lata augmented with a PLLA implant. In 16 sheep the ACL was cut from its midportion, sutured, and thereafter augmented with a PLLA implant. The tissue reactions were typical of a scant non-specific-foreign-body reaction. The number of inflammatory and giant cells was greatest at six weeks, decreasing thereafter. Degradation of the PLLA was incomplete at 48 weeks. No signs of synovitis or changes in the cartilaginous surfaces were observed. The reconstructions in both groups were anchored to the bone by fibroconnective tissue, and remodelling of the bone was seen along the drill channels. After 48 weeks the maturation of the fibroconnective tissue and the orientation of the collagen fibres were higher (p<0.01) in the fascia-lata-PLLA group than in the primarysuture-PLLA group. Histologically, the braided PLLA implants proved to be suitable for ACL repair in sheep. The augmentation of the fascia lata with the PLLA implant seemed to be preferable to that of the primary suture of the ACL. © 1993 Chapman & Hall. AD - Department of Clinical Sciences, College of Veterinary Medicine, Hämeentie 57, Helsinki, SF-00580, Finland Department of Pathology, Maria Hospital, Lapinlahdenkatu 16, Helsinki, SF-00180, Finland Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Topeliuksenkatu 5, Helsinki, SF-00260, Finland Biomaterials Laboratory, Tampere University of Technology, PO Box 527, Tampere, SF-33101, Finland Department of Surgery, Maria Hospital, Lapinlahdenkatu 16, Helsinki, SF-00180, Finland AU - Laitinen, O. AU - Alitalo, I. AU - Toivonen, T. AU - Vasenius, J. AU - Törmälä, P. AU - Vainionpää, S. DB - Scopus DO - 10.1007/BF00125592 IS - 6 M3 - Article N1 - Cited By :9 Export Date: 10 November 2020 PY - 1993 SP - 547-554 ST - Tissue response to a braided poly-L-lactide implant in an experimental reconstruction of anterior cruciate ligament T2 - Journal of Materials Science: Materials in Medicine TI - Tissue response to a braided poly-L-lactide implant in an experimental reconstruction of anterior cruciate ligament UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027733835&doi=10.1007%2fBF00125592&partnerID=40&md5=34aea8e469e1e0699cb3fc8bca9d176b VL - 4 ID - 1729 ER - TY - JOUR AB - In this study, the in vivo biocompatibility of physically crosslinked dextran hydrogels was investigated. These hydrogels were obtained by mixing aqueous solutions of dextran grafted with l-lactic acid oligomers and dextran grafted with d-lactic acid oligomers. Gelation occurs due to stereocomplex formation of the lactic acid oligomers of opposite chirality. Since gelation takes some time, in situ gel formation is possible with this system. A number of sterilization methods was evaluated for their effect on the chemical and physical properties of the hydrogel. It was shown that of the investigated options (filtration, gamma irradiation, dry-heat and autoclaving) dry-heat sterilization was the preferred method to prepare sterile gels suitable for in vivo evaluations. Two types of stereocomplex gels were prepared and implanted subcutaneously in rats. The tissue reaction was evaluated over a period of 30 days. A mild ongoing foreign body reaction was observed characterized by infiltration of macrophages. Giant cells were only scarcely formed and the low numbers of lymphocytes showed that priming of the immune system is hardly involved. Importantly, the gels fully degraded in vivo within 15 days, which is in good agreement with the in vitro degradation behaviour of these gels. In conclusion, stereocomplexed dextran-oligolactic gels showed good biocompatibility which makes them suitable candidates for the design of controlled release devices for pharmaceutically active proteins. © 2004 Elsevier Ltd. All rights reserved. AD - Department of Pharmaceutics, Utrecht Inst. Pharmaceutical Sci., Utrecht Univ., P.O. B., Netherlands Medical Biology, Department of Pathology-Lab Medicine, Fac. Med. Sci., Univ. Groningen, H., Netherlands Dept. of Cell Biology and Histology, Faculty of Veterinary Medicine, Utrecht Univ., P.O. B., Netherlands AU - Bos, G. W. AU - Hennink, W. E. AU - Brouwer, L. A. AU - Den Otter, W. AU - Veldhuis, T. F. J. AU - Van Nostrum, C. F. AU - Van Luyn, M. J. A. DB - Scopus DO - 10.1016/j.biomaterials.2004.10.008 IS - 18 KW - Biocompatibility Dextran Drug delivery Hydrogel In situ gelation Stereocomplex Tissue reactions M3 - Article N1 - Cited By :51 Export Date: 10 November 2020 PY - 2005 SP - 3901-3909 ST - Tissue reactions of in situ formed dextran hydrogels crosslinked by stereocomplex formation after subcutaneous implantation in rats T2 - Biomaterials TI - Tissue reactions of in situ formed dextran hydrogels crosslinked by stereocomplex formation after subcutaneous implantation in rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-11144307811&doi=10.1016%2fj.biomaterials.2004.10.008&partnerID=40&md5=7f70646a6b3fe79d7cc56d70573eed38 VL - 26 ID - 1607 ER - TY - JOUR AB - This study aimed to evaluate the tissue reaction of ethylene-vinyl acetate (EVA) in 4 different compositions and processing: EVA foamed at high pressure with ultrasound (EVACU); EVA with 15% starch foamed at high pressure with ultrasound (EVAMCU); EVA with 15% starch foamed at high pressure without ultrasound and EVA foamed at high pressure without ultrasound as future use as a porous scaffold. Scanning electron microscopy images showed the influence of starch, reducing the diameter of pores. The number of open pores was also reduced with the addition of starch. The ultrasound applied during the manufacturing of composites does not affect these characteristics. Eighteen rats were used to test the tissue reaction of materials and PTFE (polytetrafluoroethylene), proven biocompatible material. After 7, 15, and 60 days of surgery, the materials were removed and processed for microscopic evaluation and counting of the inflammatory infiltrate. The data shows inflammatory reaction similar to PTFE. However, in the quantitative analysis at 60 days, the EVACU and EVAMCU showed less quantity of mononuclear cells (p < 0.05). Thus, the results suggest that the use of ultrasound in the production method (EVA) seems to have improved cell behavior regarding the reduction of infiltration over the period, with tissue response equivalent to the PTFE. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 107B: 400–407, 2019. © 2018 Wiley Periodicals, Inc. AD - Universidade do Sagrado Coração-USC, Bauru, São Paulo, Brazil Universidade Estadual Paulista (UNESP), Faculdade de Ciências e Engenharia, Tupã, Brazil University of Valladolid (UVA), Valladolid, Spain AU - Froes, B. AU - Holgado, L. A. AU - Simões, R. D. AU - Velasco Nieto, D. AU - Angel Rodriguez Perez, M. AU - Kinoshita, A. DB - Scopus DO - 10.1002/jbm.b.34131 IS - 2 KW - biocompatibility biomaterial ethylene-vinyl acetate porous scaffolds tissue reaction M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 400-407 ST - Tissue reaction after subcutaneous implants of a new material composed of ethylene-vinyl acetate and starch for future use as a biomaterial T2 - Journal of Biomedical Materials Research - Part B Applied Biomaterials TI - Tissue reaction after subcutaneous implants of a new material composed of ethylene-vinyl acetate and starch for future use as a biomaterial UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85045200173&doi=10.1002%2fjbm.b.34131&partnerID=40&md5=c5390a88a80b53239cde1397ccbeed87 VL - 107 ID - 1026 ER - TY - JOUR AN - 105425536. Language: English. Entry Date: 20091002. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical DB - ccm DP - EBSCOhost IS - 9 KW - Retained Instruments -- Epidemiology Retained Instruments -- Prevention and Control Surgical Count Procedure -- Methods N1 - Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2009 SN - 0190-5066 SP - 91-92 ST - Tips for reducing retained surgical items T2 - Same-Day Surgery TI - Tips for reducing retained surgical items UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105425536&site=ehost-live&scope=site VL - 33 ID - 905 ER - TY - JOUR AB - Throat packs (TP) may be inserted to absorb and prevent debris created by intra-oral surgery tracking into the oesophagus or trachea. Retention of a TP can lead to airway obstruction with potential morbidity and mortality. The National Patient Safety Agency (NPSA) produced a safety notice in 2009 aimed at reducing risk of TP retention by improving and standardising visual and documentary safety procedures [1]. In the 2012 Department of Health update retention of foreign body post surgery was stated as a never event [2]. Following two critical incidents in our trust involving retention of TP, practice was reviewed and improvements implemented to minimise future risk. In one case procedural failure led to retention of pack while in the other a portion of an inadvertently torn TP remained concealed. Neither patient came to harm but willingness to learn from near misses focused attention on the issue. Interventions included introduction of a tear-resistant TP, emphasis on inclusion of TP in the swab count and as part of the world health organization (WHO) checklist and circulation of locally adapted safety procedures to staff. Following this, awareness of the NPSA safety procedures and a snapshot of actual practice were audited. Methods Awareness of safety procedures was assessed with a survey distributed to the multi-disciplinary team (MDT). Statistical analysis was performed using chisquared with significance at P < 0.05. During 20 cases in which a TP was used, practice was assessed against the NPSA algorithm. Results Fifty three survey responses were obtained. Labelling the patient/airway was the most commonly cited visual safety procedure (89% of responders). Scrub staff were more likely to identify inclusion of TP in the swab count as a documentary safety procedure than anaesthetic trainees, with statistical significance (X2 (1) = 4.68, P = 0.03), reflecting differences in roles. Only 15% of responders were aware of the local safety policy to keep the TP visible until the patient has left theatre in order to confirm removal. Audit of practice revealed 100% achievement of minimum safety procedures: in all 20 cases at least one visual and one documentary procedure were implemented. Discussion Critical incidents can be a catalyst for education and safety development. Awareness of procedures was good across the MDT though there is room for improvement. Implementation of safety measures exceeded the minimum standards set by the NPSA. Regular education and ongoing attention to the quality of communication and WHO checklists will be required to maintain standards. TPs are rarely used in the US compared with the UK suggesting subjectivity rather than evidence based practice [1]. Rationalising TP usage represents an important additional safety measure. AD - C. Donohue, University College Hospital (UCLH), United Kingdom AU - Donohue, C. AU - Ranasinghe, U. AU - Bouras, I. AU - Clarke, S. DB - Embase DO - 10.1111/anae.12765 KW - anesthetic agent safety catalyst clinical audit human throat procedures checklist risk patient education World Health Organization morbidity lacrimal fluid airway obstruction surgery trachea United Kingdom foreign body interpersonal communication achievement policy health statistical analysis patient safety algorithm mortality student statistical significance esophagus evidence based practice oral surgery LA - English M3 - Conference Abstract N1 - L71529368 2014-07-18 PY - 2014 SN - 0003-2409 SP - 71 ST - Throat pack safety-critical incidents as a catalyst for audit and improvement T2 - Anaesthesia TI - Throat pack safety-critical incidents as a catalyst for audit and improvement UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71529368&from=export http://dx.doi.org/10.1111/anae.12765 VL - 69 ID - 445 ER - TY - JOUR AB - BACKGROUND: Medical errors such as retained foreign bodies (RFB) during surgery are not well studied. To define risk factors associated with this type of error, we performed retrospective study. METHODS: We reviewed medical records for unintentional foreign object remaining in the body during surgery such as gender, age, surgery ward, and incident reports referred to several forensic medicine administrations as well as adverse effects of retained foreign bodies and methods for detection of them over a 3-years period from January 2008 through May 2011. RESULTS: Thirty eight patients were involved in the study to have retained foreign bodies (73% sponges and 27% other instruments including 7 (18.42%) cases of other bandages, 2 cases (5.26%) of scissor and 1 case (2.63%) of forceps). The general surgery ward was most commonly involved (47%) followed by the gynecology surgery ward (34%). Men (58%) were more involved with RFB than women (42%). CONCLUSION: Considering the most frequent type of retained foreign bodies and also more frequent involved surgery wards besides detection methods for RFB, a mixed of preventing protocols such as regular counting of devices, post-operative X-ray with radiopaque markers and exact evaluation of surgery site should be employed to reduce the occurrence of retained foreign bodies and its complications. AD - Legal Medicine Research Center, Legal Medicine Organization, Tehran and Member of Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Legal Medicine Research Center, Legal Medicine Organization, Tehran, Iran. Department of Surgery, School of Medicine, Shiraz and Hormozgan University of Medical Sciences, Bandar Abbas, Iran. AN - 28217303 AU - Zarenezhad, M. AU - Gholamzadeh, S. AU - Hedjazi, A. AU - Soltani, K. AU - Gharehdaghi, J. AU - Ghadipasha, M. AU - Hosseini, S. M. AU - Zare, A. C2 - PMC5302138 DA - Mar DO - 10.1016/j.amsu.2017.01.019 DP - NLM ET - 2017/02/22 KW - Medical error Retained foreign body Surgery LA - eng N1 - 2049-0801 Zarenezhad, Mohammad Gholamzadeh, Saeed Hedjazi, Arya Soltani, Kamran Gharehdaghi, Jaber Ghadipasha, Masoud Hosseini, Seyyed Mohammad Vahid Zare, Ahmad Journal Article Ann Med Surg (Lond). 2017 Jan 25;15:22-25. doi: 10.1016/j.amsu.2017.01.019. eCollection 2017 Mar. PY - 2017 SN - 2049-0801 (Print) 2049-0801 SP - 22-25 ST - Three years evaluation of retained foreign bodies after surgery in Iran T2 - Ann Med Surg (Lond) TI - Three years evaluation of retained foreign bodies after surgery in Iran VL - 15 ID - 190 ER - TY - JOUR AD - Division of Emergency Medicine and Urgent Care, Department of Pediatrics, Children's Mercy Hospital and Clinics, Kansas City, MO, United States AU - Shastri, N. AU - Pham, T. DB - Scopus DO - 10.1016/j.jemermed.2015.08.005 IS - 2 M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2016 SP - e93-e95 ST - Thorn injury osteomyelitis T2 - Journal of Emergency Medicine TI - Thorn injury osteomyelitis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84957839291&doi=10.1016%2fj.jemermed.2015.08.005&partnerID=40&md5=77564cb17277c12feeea4b5be85b9fc8 VL - 50 ID - 1191 ER - TY - JOUR AB - Mesenchymal stromal/stem cells (MSCs) are considered promising cellular therapeutics in the fields of tissue engineering and regenerative medicine. MSCs secrete high concentrations of immunomodulatory cytokines and growth factors, which exert paracrine effects on infiltrating immune and resident cells in the wound microenvironment that could favorably promote healing after acute injury. However, better spatial delivery and improved retention at the site of injury are two factors that could improve the clinical application of MSCs. In this study, we utilized thiol-ene Michael-type addition for rapid encapsulation of MSCs within a gelatin/poly(ethylene glycol) biomatrix. This biomatrix was also applied as a provisional dressing to full thickness wounds in Sprague-Dawley rats. The three-way interaction of MSCs, gelatin/poly(ethylene glycol) biomatrices, and host immune cells and adjacent resident cells in the wound microenvironment favorably modulated wound progression and host response. In this model we observed attenuated immune cell infiltration, lack of foreign giant cell (FBGC) formation, accelerated wound closure and re-epithelialization, as well as enhanced neovascularization and granulation tissue formation by 7 days. The MSC entrapped in the gelatin/poly(ethylene glycol) biomatrix localized cell presentation adjacent to the wound microenvironment and thus mediated the early resolution of inflammatory events and facilitated the proliferative phases in wound healing. © 2013 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved. AD - School of Pharmacy, Division of Pharmaceutical Sciences, University of Wisconsin-Madison, 777 Highland Avenue, Madison, WI 53705, United States Quishi Academy for Advanced Studies, Zhejiang University, Hangzhou 310027, China Department of Biomedical Engineering, College of Engineering, University of Wisconsin-Madison, Madison, WI 53705, United States Department of Cellular and Molecular Biology, University of Wisconsin-Madison, Madison, WI 53705, United States Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, United States University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI 53705, United States Department of Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, United States AU - Xu, K. AU - Cantu, D. A. AU - Fu, Y. AU - Kim, J. AU - Zheng, X. AU - Hematti, P. AU - Kao, W. J. DB - Scopus DO - 10.1016/j.actbio.2013.06.021 IS - 11 KW - Cell-based therapy Foreign body response Inflammation Macrophages Mesenchymal stem cells M3 - Article N1 - Cited By :47 Export Date: 10 November 2020 PY - 2013 SP - 8802-8814 ST - Thiol-ene Michael-type formation of gelatin/poly(ethylene glycol) biomatrices for three-dimensional mesenchymal stromal/stem cell administration to cutaneous wounds T2 - Acta Biomaterialia TI - Thiol-ene Michael-type formation of gelatin/poly(ethylene glycol) biomatrices for three-dimensional mesenchymal stromal/stem cell administration to cutaneous wounds UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84885036993&doi=10.1016%2fj.actbio.2013.06.021&partnerID=40&md5=9ee92f26fc669bfda0aecedc7a07aabf VL - 9 ID - 1346 ER - TY - JOUR AD - senior nurse in the plastics operating theatre at Middlemore Hospital, Auckland. AN - 104686081. Language: English. Entry Date: 20111014. Revision Date: 20150820. Publication Type: Journal Article. Journal Subset: Australia & New Zealand AU - Bittle, Mark DB - ccm DP - EBSCOhost IS - 7 KW - Checklists -- Utilization Patient Safety Consent Consumer Participation Meetings Operating Room Personnel Patient Identification Perioperative Nursing Surgical Count Procedure Surgical Site Verification N1 - Editorial Board Reviewed; Nursing; Peer Reviewed. Special Interest: Patient Safety; Perioperative Care. NLM UID: 9507374. PMID: NLM21957547. PY - 2011 SN - 1173-2032 SP - 16-17 ST - Theatre team learns to use checklist to make surgery safer T2 - Kai Tiaki Nursing New Zealand TI - Theatre team learns to use checklist to make surgery safer UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104686081&site=ehost-live&scope=site VL - 17 ID - 841 ER - TY - JOUR AB - Retaining of gauzes and surgical sponges in the abdomen is one of the most frequent medical errors usually manifesting as abscess or abdomino-cutaneus fistulas with no definite symptoms during lifetime. Here, we introduce a 35 year old woman with symptoms and signs of partial bowel obstruction and enterocutaneous fistulas caused by migration of retained gauze from abdominal cavity to terminal ileum, 9 months after cesarean section. This is called "Textiloma". There are several reports of gossypiboma worldwide but migration of retained gauze into intestine causing an enterocutaneous fistula is rare. AD - Department of General Surgery, Shohada Teaching Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran Department of Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran AU - Govarjin, H. M. AU - Talebianfar, M. AU - Fattahi, F. AU - Akbari, M. E. DB - Scopus IS - 1 KW - Foreign body Gossypiboma Retained surgical towel Surgical error M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2010 SP - 54-57 ST - Textiloma, migration of retained long gauze from abdominal cavity to intestine T2 - Journal of Research in Medical Sciences TI - Textiloma, migration of retained long gauze from abdominal cavity to intestine UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-75649127282&partnerID=40&md5=137df83fa6fead6f2e28aaf95a4824ae VL - 15 ID - 1473 ER - TY - JOUR AB - Transsphenoidal surgery is the mainstream in the management of sellar and anterior fossa diseases. However, textiloma, as known as cotton left behind during an operation, is rarely reported as a complication of transsphenoidal surgery. In this paper, we present a case of textiloma after transsphenoidal surgery. The patient had been suffering progressive blurred vision and she received transsphenoidal surgery for the diagnosis of pituitary tumor. However, the intermittent headaches persisted for half a year after the surgery. The subsequent images revealed a rim-like enhanced tumor in the sellar region. The retained cotton material was found when she underwent transcranial surgery. The etiology and management of textiloma are discussed, and the relevant literature also reviewed. AD - Department of Neurological Surgery, Tri-Service General Hospital, Taipei, Taiwan Department of Pathology, Tri-Service General Hospital, Taipei, Taiwan Department of Surgery, Sijhih Cathay General Hospital, New Taipei, Taiwan Division of Neurosurgery, Department of Surgery, Army Force Taichung General Hospital, Taichung, Taiwan AU - Hsieh, C. T. AU - Chung, T. T. AU - Chen, Y. H. AU - Li, Y. F. AU - Liu, M. Y. DB - Scopus IS - 4 M3 - Review N1 - Cited By :2 Export Date: 10 November 2020 PY - 2011 SP - 369-371 ST - Textiloma as a complication of transsphenoidal surgery T2 - Neurosciences TI - Textiloma as a complication of transsphenoidal surgery UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-80054679638&partnerID=40&md5=d26ce7503224ef5c4d7a9d621e58786c VL - 16 ID - 1406 ER - TY - JOUR AB - A 63-year-old woman underwent cardiac surgery, with atrial and ventricular temporary epicardial pacing wires being placed at the end of the procedure. Four months after the operation, the patient experienced tooth decay and underwent a tooth extraction. Thereafter, the patient developed an infected, swollen neck; computed tomography revealed that one of the temporary pacing wires had migrated into her neck. The patient was readmitted for removal of the wire, but it spontaneously exited through the skin of the lower jaw; the infection was resolved with intravenous antibiotic therapy. © 2014 The Society of Thoracic Surgeons. AD - Department of Cardiovascular Surgery, Hayama Heart Center, 1898-1 Shimoyamaguchi, Hayama, Kanagawa, 240-0166, Japan AU - Kondo, T. AU - Hirota, M. AU - Hoshino, J. AU - Takahashi, Y. AU - Notomi, Y. AU - Isomura, T. DB - Scopus DO - 10.1016/j.athoracsur.2014.02.055 IS - 6 M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2014 SP - 2221-2223 ST - Temporary epicardial pacing wire migrating to and exiting from the jaw T2 - Annals of Thoracic Surgery TI - Temporary epicardial pacing wire migrating to and exiting from the jaw UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84919416687&doi=10.1016%2fj.athoracsur.2014.02.055&partnerID=40&md5=90822db91cf52b78ece9c4c0771ae9f8 VL - 98 ID - 1280 ER - TY - JOUR AB - INTRODUCTION AND OBJECTIVE: Retained surgical items (RSIs) remain the most frequently encountered sentinel event despite increased vigilance and improved patient safety measures. Recently, a greater emphasis has been placed on improving teamwork and communication in the OR to aid in the prevention of RSI events. Unfortunately, time spent on preventative measures and management of RSIs, especially sharps (i.e. needle, instrument, wire, fragment) is a neglected topic in current literature. This study's objective was to compare how different members of the OR team perceive near-miss and retained surgical sharp events, as this may influence team communication and increase the opportunity for undue patient harm. METHODS: An anonymous survey with 13 questions regarding demographics (6) and perception of near-misses and retained surgical sharps in the last year (7) was distributed electronically to OR staff at three high volume institutions. Responses were ranked in Excel and analyzed by Mann-Whitney U test or Kruskal-Wallis ANOVA test. RESULTS: 30 surgical nurses, 25 surgeons and 12 anesthesiologists responded to the survey. When comparing OR nurses to surgeons, there was no difference in the reported approximate time spent searching for lost sharps (21-30 min, p=0.14), the effectiveness of portable X-ray to help recover RSIs (26-50%, p=0.33) and the amount of time added to the OR due to the use of the X-ray (41-50 min, p=0.8). However, there was significant discordance between surgeons' and nurses' perceptions of the frequency of lost surgical sharps (p=0.025), the frequency of miscounted surgical sharps (p=0.003), and the frequency of lost surgical sharps not recovered (p=0.003). Percentages are listed in Table 1. When performing Kruskal-Wallis ANOVA test to include anesthesiologists, improvement in perception are seen in all categories. CONCLUSIONS: These data provide initial evidence that OR staff may perceive the frequency of near-miss and retained surgical sharps differently. This hints at a lack of communication regarding these sentinel events. Patient safety can be negatively impacted if certain members of the OR team are not aware of lost, miscounted or retained surgical sharps. Further research is needed to evaluate the impact this may have on patient safety, OR culture and the effective reporting of RSI events. (Table Presented). AD - S. Weprin, Richmond, VA, United States AU - Weprin, S. AU - Siev, M. AU - Li, R. AU - Maddra, K. AU - Cho, E. AU - Nandanan, N. AU - Klausner, A. AU - Hampton, L. AU - Autorino, R. DB - Embase DO - 10.1097/JU.0000000000000975.02 KW - adult analysis of variance anesthesiologist conference abstract controlled study demography drug safety human nurse operating room patient harm perception rank sum test sentinel event surgeon teamwork X ray LA - English M3 - Conference Abstract N1 - L632060961 2020-07-24 PY - 2020 SN - 1527-3792 SP - e1255-e1256 ST - Teamwork in the operating room: How different perceptions of sentinel events may negatively impact patient safety T2 - Journal of Urology TI - Teamwork in the operating room: How different perceptions of sentinel events may negatively impact patient safety UR - https://www.embase.com/search/results?subaction=viewrecord&id=L632060961&from=export http://dx.doi.org/10.1097/JU.0000000000000975.02 VL - 203 ID - 279 ER - TY - JOUR AB - Preventable medical errors in the operating room are most often caused by ineffective communication and suboptimal team dynamics. TeamSTEPPS is a government-funded, evidence-based program that provides tools and education to improve teamwork in medicine. The study hospital implemented TeamSTEPPS in the operating room and merged the program with a surgical safety checklist. Audits were performed to collect both quantitative and qualitative information on time out (brief) and debrief conversations, using a standardized audit tool. A total of 1610 audits over 6 months were performed by live auditors. Performance was sustained at desired levels or improved for all qualitative metrics using χ(2) and linear regression analyses. Additionally, the absolute number of wrong site/side/person surgery and unintentionally retained foreign body counts decreased after TeamSTEPPS implementation. AD - 1 The Mount Sinai Hospital, New York, NY. 2 FOJP Service Corporation, New York, NY. AN - 27516608 AU - Rhee, A. J. AU - Valentin-Salgado, Y. AU - Eshak, D. AU - Feldman, D. AU - Kischak, P. AU - Reich, D. L. AU - LoPachin, V. AU - Brodman, M. DA - Jul/Aug DO - 10.1177/1062860616662703 DP - NLM ET - 2016/08/16 IS - 4 KW - Checklist Clinical Audit/*organization & administration/standards *Communication Humans Inservice Training/*organization & administration Medical Errors/prevention & control Operating Rooms/organization & administration Patient Care Team/*organization & administration/standards Patient Safety/standards Perioperative Care/*standards Quality Improvement/organization & administration Safety Management/organization & administration TeamSTEPPS communication perioperative teamwork LA - eng N1 - 1555-824x Rhee, Amanda J Valentin-Salgado, Yessenia Eshak, David Feldman, David Kischak, Pat Reich, David L LoPachin, Vicki Brodman, Michael Journal Article United States Am J Med Qual. 2017 Jul/Aug;32(4):369-375. doi: 10.1177/1062860616662703. Epub 2016 Aug 10. PY - 2017 SN - 1062-8606 SP - 369-375 ST - Team Training in the Perioperative Arena: A Methodology for Implementation and Auditing Behavior T2 - Am J Med Qual TI - Team Training in the Perioperative Arena: A Methodology for Implementation and Auditing Behavior VL - 32 ID - 182 ER - TY - JOUR AB - Objective: Osteosynthesis-associated infection is a challenging complication post fracture fixation, burdening the patients and the orthopaedic surgeons alike. A clinically relevant animal model is critical in devising new therapeutic strategies. Our aim was to perform a systematic review to evaluate existing preclinical models and identify their applications in aspects of animal selection, bacterial induction, fracture fixation and complications. Methods: A systematic literature research was conducted in PubMed and Embase up to February 2020. A total of 31 studies were included. Information on the animal, bacterial induction, fracture fixation, healing result and complications were extracted. Results: Animals selected included murine (23), rabbit (6), ewe (1) and goat (1). Larger animals had enabled the use of human-sized implant, however small animals were more economical and easier in handling. Staphylococcus aureus (S. aureus) was the most frequently chosen bacteria for induction. Bacterial inoculation dose ranged from 102−8 ​CFU. Consistent and replicable infections were observed from 104 ​CFU in general. Methods of inoculation included injections of bacterial suspension (20), placement of foreign objects (8) and pretreatment of implants with established biofilm (3). Intramedullary implants (13), plates and screws (18) were used in most models. Radiological (29) and histological evaluations (24) in osseous healing were performed. Complications such as instability of fracture fixation (7), unexpected surgical death (5), sepsis (1) and persistent lameness (1) were encountered. Conclusion: The most common animal model is the S. aureus infected open fracture internally fixated. Replicable infections were mainly from 104 ​CFU of bacteria. However, with the increase in antibiotic resistance, future directions should explore polymicrobial and antibiotic resistant strains, as these will no doubt play a major role in bone infection. Currently, there is also a lack of osteoporotic bone infection models and the pathophysiology is unexplored, which would be important with our aging population. The translational potential of this article: This systematic review provides an updated overview and compares the currently available animal models of osteosynthesis-associated infections. A discussion on future research directions and suggestion of animal model settings were made, which is expected to advance the research in this field. © 2020 The Authors AD - Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong School of Pharmacy, The Chinese University of Hong Kong, Hong Kong Department of Microbiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong AU - Wong, R. M. Y. AU - Li, T. K. AU - Li, J. AU - Ho, W. T. AU - Chow, S. K. H. AU - Leung, S. S. Y. AU - Cheung, W. H. AU - Ip, M. DB - Scopus DO - 10.1016/j.jot.2020.03.002 KW - Animal models Fracture Infection models Osteosynthesis-associated infection Systematic review M3 - Review N1 - Cited By :1 Export Date: 10 November 2020 PY - 2020 SP - 8-20 ST - A systematic review on current osteosynthesis-associated infection animal fracture models T2 - Journal of Orthopaedic Translation TI - A systematic review on current osteosynthesis-associated infection animal fracture models UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85084438588&doi=10.1016%2fj.jot.2020.03.002&partnerID=40&md5=fcd6729989e8824a8c73353774a83d4c VL - 23 ID - 960 ER - TY - JOUR AB - Throat packs are commonly inserted by anaesthetists after induction of anaesthesia for dental, maxillofacial, nasal or upper airway surgery. However, the evidence supporting this practice as routine is unclear, especially in the light of accidentally retained throat packs which constitute ‘Never Events’ as defined by NHS England. On behalf of three relevant national organisations, we therefore conducted a systematic review and literature search to assess the evidence base for benefit, and also the extent and severity of complications associated with throat pack use. Other than descriptions of how to insert throat packs in many standard texts, we could find no study that sought to assess the benefit of their insertion by anaesthetists. Instead, there were many reports of minor and major complications (the latter including serious postoperative airway obstruction and at least one death), and many descriptions of how to avoid complications. As a result of these findings, the three national organisations no longer recommend the routine insertion of throat packs by anaesthetists but advise caution and careful consideration. Two protocols for pack insertion are presented, should their use be judged necessary. AD - J.J. Pandit, Nuffield Department of Anaesthetics, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom AU - Athanassoglou, V. AU - Patel, A. AU - McGuire, B. AU - Higgs, A. AU - Dover, M. S. AU - Brennan, P. A. AU - Banerjee, A. AU - Bingham, B. AU - Pandit, J. J. DB - Embase Medline DO - 10.1111/anae.14197 IS - 5 KW - surgical sponge throat pack airway obstruction anesthesist glossopharyngeal nerve injury human infection patient safety postoperative nausea and vomiting review systematic review throat culture LA - English M3 - Review N1 - L620223044 2018-01-19 2018-04-24 PY - 2018 SN - 1365-2044 0003-2409 SP - 612-618 ST - Systematic review of benefits or harms of routine anaesthetist-inserted throat packs in adults: practice recommendations for inserting and counting throat packs: An evidence-based consensus statement by the Difficult Airway Society (DAS), the British Association of Oral and Maxillofacial Surgery (BAOMS) and the British Association of Otorhinolaryngology, Head and Neck Surgery (ENT-UK) T2 - Anaesthesia TI - Systematic review of benefits or harms of routine anaesthetist-inserted throat packs in adults: practice recommendations for inserting and counting throat packs: An evidence-based consensus statement by the Difficult Airway Society (DAS), the British Association of Oral and Maxillofacial Surgery (BAOMS) and the British Association of Otorhinolaryngology, Head and Neck Surgery (ENT-UK) UR - https://www.embase.com/search/results?subaction=viewrecord&id=L620223044&from=export http://dx.doi.org/10.1111/anae.14197 VL - 73 ID - 347 ER - TY - JOUR AB - As any perinatal nurse knows, retained vaginal sponges are an obstetrical and postpartum patient safety problem. As surgical sponge counts are not routine in some obstetrical units for vaginal births, our healthcare system chose to institute a rigorous process to eliminate retained sponges in all vaginal births. This article describes this process, along with the lessons learned, when Catholic Healthcare West implemented the Sponge ACCOUNTing System in its 32 hospitals in California, Arizona, and Nevada. Implementation of this process involved the standardization of practice for obstetricians, certified nurse midwives, nurses, obstetric technicians, radiologists, and radiology technicians in the management and accounting of surgical sponges. AD - Catholic Healthcare West, Rancho Cordova, CA, USA. Brenda.Chagolla@chw.edu AN - 21857202 AU - Chagolla, B. A. AU - Gibbs, V. C. AU - Keats, J. P. AU - Pelletreau, B. DA - Sep-Oct DO - 10.1097/NMC.0b013e31822ab204 DP - NLM ET - 2011/08/23 IS - 5 KW - Arizona California Female Foreign Bodies/*prevention & control Humans Medical Errors/prevention & control Nevada Nurse Midwives/standards Obstetric Nursing/standards Obstetrics/methods/*standards Pregnancy *Safety Management Surgical Sponges/*adverse effects Technology, Radiologic/standards LA - eng N1 - 1539-0683 Chagolla, Brenda A Gibbs, Verna C Keats, John P Pelletreau, Barbara Journal Article United States MCN Am J Matern Child Nurs. 2011 Sep-Oct;36(5):312-7. doi: 10.1097/NMC.0b013e31822ab204. PY - 2011 SN - 0361-929x SP - 312-7 ST - A system-wide initiative to prevent retained vaginal sponges T2 - MCN Am J Matern Child Nurs TI - A system-wide initiative to prevent retained vaginal sponges VL - 36 ID - 111 ER - TY - JOUR AB - This study was designed to evaluate the efficacy of focal hyperthermia and rifampin in vitro and in vivo using a rabbit model of foreign-body infection by methicillin-resistant Staphylococcus aureus (MRSA). In vitro studies demonstrated bacterial re-growth and development of rifampin resistance after 24 h with rifampin alone, which was prevented under hyperthermic conditions. For the in vivo studies, rifampin was administered intraperitoneally every 12 h for 7 days to rabbits with MRSA-containing cages implanted into their flanks. When combined with hyperthermia at 39°C, 41°C and 43°C, rifampin significantly reduced in-cage bacterial counts by > 3.0 log10 colony forming units/ml compared with rifampin alone. Eradication of cage-associated infection was achieved more effectively when rifampin was combined with hyperthermia, with cure rates of 70-95% on day 10. Focal hyperthermia combined with rifampin prevented the emergence of rifampin resistance and maintained rifampin efficacy. These findings might have implications for orthopaedic surgery. Copyright © 2009 Field House Publishing LLP. AD - Department of Orthopaedics, Sixth Affiliated People's Hospital, Shanghai Jiaotong University, Shanghai 200233, China AU - Zou, G. Y. AU - Shen, H. AU - Jiang, Y. AU - Zhang, X. L. DB - Scopus DO - 10.1177/147323000903700416 IS - 4 KW - Antibiotics Focal hyperthermia Foreign-body infection Methycillin-resistant staphylococcus aureus Rifampin M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2009 SP - 1115-1126 ST - Synergistic effect of a novel focal hyperthermia on the efficacy of rifampin in staphylococcal experimental foreign-body infection T2 - Journal of International Medical Research TI - Synergistic effect of a novel focal hyperthermia on the efficacy of rifampin in staphylococcal experimental foreign-body infection UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-70350490518&doi=10.1177%2f147323000903700416&partnerID=40&md5=c828c82b7bc8a214219119e5502e2245 VL - 37 ID - 1502 ER - TY - JOUR AB - Introduction Giant peritoneal loose bodies (gPLB) occur rarely and therefore only few have been described. Often they are found incidentally and have no clinical relevance, whereas symptomatic forms may require surgical removal. Presentation of case We report the case of a male patient suffering from abdominal discomfort with alternating localizations for several years, actually presenting with a proctitis. With elevated inflammatory markers, a conspicuous resistance in the lower abdomen and in order to evaluate further affection of the colon, an abdominal CT-scan was performed. It revealed a spherical mass in the lesser pelvis. A colonoscopy confirmed the proctitis, showing no further pathologies. Due to the symptoms and the uncertain entity of the mass, a diagnostic laparoscopy was performed and a boiled egg-like structure (diameter 5.2 cm) was removed. The patient recovered well and was free of symptoms. Discussion The patient had two potential reasons for his symptoms, one of them being a suspected leftover foreign body years after an appendectomy. The proctitis was treated conservatively but without complete remission of the abdominal discomfort. Therefore, a diagnostic laparoscopy was performed and the mass turned out to be a gPLB. Conclusion To obtain a fast diagnosis and to perform an adequate conservative or surgical therapy, the knowledge about the rare entity of a gPLB is necessary. An exact anamnesis, clinical examination and the knowledge about the diagnostic values of radiological and endoscopic investigations are crucial. © 2016 The Authors. AD - Department of Surgery, Hospital of Baselland-Liestal, Rheinstrasse 26, Liestal, 4410, Switzerland Clinical Trial Unit, HIRSLANDEN Private Hospital Group, Klinik Hirslanden, Zurich, Switzerland Department of Pathology, Hospital of Baselland-Liestal, Rheinstrasse 26, Liestal, 4410, Switzerland AU - Elsner, A. AU - Walensi, M. AU - Fuenfschilling, M. AU - Rosenberg, R. AU - Robert, M. DB - Scopus DO - 10.1016/j.ijscr.2016.02.013 KW - Abbreviations PLB peritoneal loose body gPLB giant peritoneal loose body M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2016 SP - 32-35 ST - Symptomatic giant peritoneal loose body in the pelvic cavity: A case report T2 - International Journal of Surgery Case Reports TI - Symptomatic giant peritoneal loose body in the pelvic cavity: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84958817381&doi=10.1016%2fj.ijscr.2016.02.013&partnerID=40&md5=5234654f75e7fcae5c45297c85e368df VL - 21 ID - 1206 ER - TY - JOUR AB - BACKGROUND: The aim of this study is to report a case of sympathetic ophthalmia with sensorineural hearing loss following penetrating trauma. This is an interventional case report. A 23-year-old male presented with bilateral, sudden, profound visual and hearing loss, disorientation, and dizziness. He had a past history of penetrating trauma with an iron rod in the right eye for which he underwent scleral tear repair, vitreo-retinal surgery with intraocular foreign body removal and silicon oil injection. His best corrected visual acuity in the right eye was counting fingers close to the face and was perception of light in the left eye. Clinical evaluation with slit biomicroscopy, indirect ophthalmoscopy, ultrasonography, and pure tone audiometry was suggestive of sympathetic ophthalmia with sensorineural hearing loss. Treatment was started with intravenous methyl prednisolone, oral corticosteroids, and immunosuppressants. FINDINGS: Following treatment, signs of panuveitis showed resolution and improvement in visual, hearing, and neurological symptoms. CONCLUSIONS: Sympathetic ophthalmia associated with sensorineural deafness and neurological symptoms is a rare clinical syndrome. Prompt diagnosis and treatment with systemic corticosteroids and immunosuppressant medication may result in clinical improvement. AD - Eye Department, Dr Shroff Charity Eye Hospital, 5027, Kedarnath Road, Daryaganj, New Delhi 110002, India. vramesh80@yahoo.com. AN - 24225003 AU - Venkatesh, R. AU - Agarwal, M. AU - Ramesh, V. J. AU - Singh, S. AU - Kantha, M. AU - Biswas, J. C2 - PMC4177530 DA - Nov 13 DO - 10.1186/1869-5760-3-65 DP - NLM ET - 2013/11/15 IS - 1 LA - eng N1 - 1869-5760 Venkatesh, Ramesh Agarwal, Manisha Ramesh, Vidya Janaki Singh, Shalini Kantha, Meha Biswas, Jyotirmay Journal Article J Ophthalmic Inflamm Infect. 2013 Nov 13;3(1):65. doi: 10.1186/1869-5760-3-65. PY - 2013 SN - 1869-5760 (Print) 1869-5760 SP - 65 ST - Sympathetic ophthalmia with sensorineural deafness - report of a case T2 - J Ophthalmic Inflamm Infect TI - Sympathetic ophthalmia with sensorineural deafness - report of a case VL - 3 ID - 145 ER - TY - JOUR AB - This article presents the results of an audit o f swab and instrument count practices in the operating department o f a large hospital NHS Trust in South East England. A literature review o f the subject is presented followed by the methodology used including questionnaires and observation of practice. Findings are discussed in terms of compliance with the department’s swab and instrument count policy and observed practice mapped against the recommendations for best practice in the literature. The findings show that audit of practice is still treated with suspicion by many and that a number o f practices o f scrub and circulating personnel in operating theatres need to be improved. Recommendations are made related to improving staff development in the department and introducing clinical supervision as one way to provide support for colleagues to reflect on their practice and change to more evidence-based practices in the operating department. AD - Endoscopy Unit Service Manager, Croydon Health Services NHS Trust, London Pro Vice Chancellor, Faculty of Education and Health, University of Greenwich, London AN - 107866575. Language: English. Entry Date: 20140722. Revision Date: 20200708. Publication Type: Journal Article AU - Smith, Yvonne AU - Burke, Linda DB - ccm DO - 10.12968/bjon.2014.23.11.590 DP - EBSCOhost IS - 11 KW - Surgical Count Procedure Retained Instruments -- Prevention and Control Patient Safety Audit England Operating Rooms Observational Methods Hospital Policies Professional Compliance Clinical Supervision Human Perioperative Nursing Surgeons Communication Documentation Health Care Errors National Health Programs Retained Instruments -- Epidemiology Incidence Survey Research Questionnaires Summated Rating Scaling N1 - research. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. Special Interest: Patient Safety; Perioperative Care. NLM UID: 9212059. PMID: NLM24933549. PY - 2014 SN - 0966-0461 SP - 590-593 ST - Swab and instrument count practice: ways to enhance patient safety T2 - British Journal of Nursing TI - Swab and instrument count practice: ways to enhance patient safety UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107866575&site=ehost-live&scope=site VL - 23 ID - 722 ER - TY - JOUR AB - We have proposed that it is sufficient to provide a simple substratum on which regenerating axone may traverse a gap in a peripheral nerve. To test this hypothesis we set up a new experimental model in which sutures where used to bridge a 10 mm long defect in a peripheral nerve. A defect was created bilaterally in 25 rat sciatic nerves. The cut ends of the nerve were joined by three laps of a continuous suture, on one side with 8/0 polyamide (non-absorbable) and on the other with 8/0 polyglactin (absorbable), leaving a 7 mm gap. At two weeks a matrix that contained capillaries, fibroblast-like cells, and mononuclear cells had formed between the nerve endings, and the sutures were surrounded by foreign-body-like tissue reactions. At four weeks axone had grown into the distal nerve segment on both sides in 65%-90% of the cases as indicated by a response to the pinch reflex test and immunocytochemistry for presence of neurofilament protein. Axons were organised in minifascicles and these tended to grow larger as the demarcation of the entire regenerated segment by a perineurial-like structure improved with time. At 12 weeks axonal counts of cross-sections of the distal tibial trunk showed many myelinated nerve fibres but no significant difference in axonal counts or degree of myelination between the polyamide and polyglactin sides. The results show that conventional sutures alone are sufficient to support regeneration across a short gap in a peripheral nerve, a method that may be of potential clinical value. AD - Department of Hand Surgery, Malmö Univ. Hospital, Malmö, Sweden Department of Animal Physiology, Lund University, Lund, Sweden Department of Hand Surgery, Malmö Univ. Hospital, SE 205 02 Malmö, Sweden AU - Scherman, P. AU - Lundborg, G. AU - Kanje, M. AU - Dahlin, L. B. DB - Scopus DO - 10.1080/02844310050160105 IS - 1 KW - Absorbable sutures Axonal growth Fibrin matrix Nerve regeneration Nerve repair Non-absorbable sutures Sciatic nerve M3 - Article N1 - Cited By :24 Export Date: 10 November 2020 PY - 2000 SP - 1-8 ST - Sutures alone are sufficient to support regeneration across a gap in the continuity of the sciatic nerve in rats T2 - Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery TI - Sutures alone are sufficient to support regeneration across a gap in the continuity of the sciatic nerve in rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033930253&doi=10.1080%2f02844310050160105&partnerID=40&md5=7c8da97b5ceff5aa5dbdf3912eb00dd1 VL - 34 ID - 1684 ER - TY - JOUR AB - Objective: The anastomosis of peripheral nerves is a demanding procedure that has potential complications due to foreign body reactions elicited by sutures. In this study, the sutureless in vivo anastomosis of rat tibial nerves was successfully performed, using for the first time a chitosan-based laser-activated adhesive. The nerve thermal damage caused by the laser irradiation was quantitatively assessed. Materials and Methods: A novel adhesive composed of chitosan, indocyanine green, acetic acid, and water, was fabricated in thin sheets. Its adhesive strength was tested in vitro by bonding strips (surface area ∼20 mm2, thickness ∼20 μm) onto rat sciatic nerves and sheep intestine by laser activation with low fluence (∼50 J/cm2), using a fiber-coupled diode laser (n = 13). The tensile strength of the adhesive/tissue bonds was measured after tissue repair. The chitosan adhesive was then used to perform sutureless anastomosis of tibial nerves in vivo (n = 6). Adhesive strips were also bonded in vivo onto intact rat sciatic nerves (n = 6) in order to quantitatively assess, by counting myelinated axons, the thermal damage induced by the laser. Results: The adhesive bonded well to tissue with a tensile strength of 12.5 ± 2.6 KPa (mean ± SD; n = 13). The in vivo anastomosed nerves were in continuity 3 d after surgery. Axon counting showed the number and morphology of myelinated axons were normal proximally (∼96%) compared with intact nerves (100%). Axon demyelination was observed at the operation site (∼49%) and distally (∼27%), and was attributed to laser-induced thermal damage. Conclusions: Nerve anastomosis, performed by the laser-adhesive procedure, was successful 3 d postoperatively. Proximal myelinated axons were not significantly damaged by the low laser fluence. © 2008 Mary Ann Liebert, Inc. AD - Bio/polymer Research Group, School of Biotechnology and Bimolecular Sciences, University of New South Wales, Sydney, NSW, Australia Optical and Biomedical Engineering Laboratory, School of Electrical, Electronic, and Computer Engineering, University of Western Australia, Perth, WA, Australia Graduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW, Australia School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Perth, WA, Australia School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia Prince of Wales Medical Research Institute, University of New South Wales, Sydney, NSW, Australia School of Biotechnology and Biomolecular Sciences, Samuels Building, University of New South Wales, Sydney, NSW 2052, Australia AU - Lauto, A. AU - Foster, L. J. AU - Avolio, A. AU - Sampson, D. AU - Raston, C. AU - Sarris, M. AU - McKenzie, G. AU - Stoodley, M. DB - Scopus DO - 10.1089/pho.2007.2131 IS - 3 M3 - Article N1 - Cited By :40 Export Date: 10 November 2020 PY - 2008 SP - 227-234 ST - Sutureless nerve repair with laser-activated chitosan adhesive: A pilot in vivo study T2 - Photomedicine and Laser Surgery TI - Sutureless nerve repair with laser-activated chitosan adhesive: A pilot in vivo study UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-46249102950&doi=10.1089%2fpho.2007.2131&partnerID=40&md5=e8cfa90866fd743f0f18494b31a0ada4 VL - 26 ID - 1529 ER - TY - JOUR AB - Background: Commonly used contemporary orthopaedic sutures have been identified as a potential causative factor in the development of post-arthroscopic glenohumeral chondrolysis. Currently, little is known about the body's immune response to these materials. The aim of this study was to examine the biological response of synovial tissue to three commonly used orthopaedic sutures, using a murine airpouch model. Methods: Fifty rats were used in this study (ten per group). An airpouch was created in each rat, and test materials were implanted. Test materials consisted of an intact polyethylene terephthalate suture with a polybutilate coating (suture A), an intact polyethylene suture braided around a central polydiaxannone core (suture B), an intact polyethylene/polyester cobraid suture with a silicone coating (suture C), and particles of suture C (particles C). Rats were sacrificed at 1 or 4weeks following implantation. Histological (multinucleated giant cell count) and immunohistochemical (expression of matrix metalloproteinases MMP-1,-2,-3,-9,-13) markers of inflammation were examined. Results: Multinucleated giant cells were present in all specimens containing suture material but not in the control specimens. No significant differences were found in the number of giant cells between the intact suture groups at either time point. Significantly higher numbers of giant cells were noted in the particles C group compared to the intact suture C group at both time points (p=0.021 at 1week, p=0.003 at 4weeks). Quantitative analysis of immunohistochemical staining expression at 4weeks showed that significantly more MMP (-1,-2,-9,-13) was expressed in the particles C group than the intact suture C group (p=0.024, p=0.009, p=0.002, and p=0.007 for MMP-1, MMP-2, MMP-9, and MMP-13, respectively). No significant difference was seen in the expression of MMP-3 (p=0.058). Conclusions: There were no differences observed between the biological reactivity of commonly used intact orthopaedic sutures A, B, and C. However, wear particles of suture C elicited a significantly greater inflammatory response than intact suture alone. This was confirmed by increased numbers of multinucleated giant cells as well as MMP (-1,-2,-9,-13) expression. Further studies are needed to determine whether this inflammatory response may play a role in the development of post-arthroscopic glenohumeral chondrolysis or interfere with biological healing. These findings have important clinical implications relating to surgical technique and surgical implant design. © 2018 The Author(s). AD - University of New South Wales, Surgical and Orthopaedic Research Laboratories, Prince of Wales Clinical School, Sydney, Australia St. Vincent Hospital, Orthopaedic Department, Vienna, Austria Deakin University, Barwon Centre for Orthopaedic Research and Education, School of Medicine, Waurn Ponds, Geelong, VIC, Australia AU - Lovric, V. AU - Goldberg, M. J. AU - Heuberer, P. R. AU - Oliver, R. A. AU - Stone, D. AU - Laky, B. AU - Page, R. S. AU - Walsh, W. R. C7 - 311 DB - Scopus DO - 10.1186/s13018-018-1026-4 IS - 1 KW - Foreign body reaction Inflammatory response Matrix metalloproteinase Post-arthroscopic glenohumeral chondrolysis Suture Suture wear particles M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2018 ST - Suture wear particles cause a significant inflammatory response in a murine synovial airpouch model T2 - Journal of Orthopaedic Surgery and Research TI - Suture wear particles cause a significant inflammatory response in a murine synovial airpouch model UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85058064458&doi=10.1186%2fs13018-018-1026-4&partnerID=40&md5=43380f1763c02c3be0470441d8c80091 VL - 13 ID - 1050 ER - TY - JOUR AB - BACKGROUND AND IMPORTANCE: Chopsticks are common utensils used in many Asian cultures. However, they sometimes can be used as weapons or can cause accidents, particularly in children. Penetrating transorbital/transpharyngeal intracranial injuries with bamboo sticks are peculiar accidents and are relatively rare. Because of their rarity, the management of such injuries is often complex. We discuss 3 cases of penetration of the brainstem by bamboo sticks, 1 case through the foramen magnum, which, to the best of our knowledge, is the first reported case of such an injury. CLINICAL PRESENTATION: The case of a 50-year-old man who was stabbed with a pair of chopsticks in his left eye is presented. The chopsticks passed through the cavernous sinus, and the patient sustained superior orbital fissure syndrome. The other 2 cases were those of a 4-year-old girl having a similar pattern but different mechanism of injury and a 2-year-old boy who sustained transpharyngeal intracranial injury via the foramen magnum. Computed tomography, magnetic resonance imaging, and computed tomographic angiography (CTA) are the key imaging modalities frequently used to determine the course and extent of brain injury. CONCLUSION: Early surgical exploration by a multidisciplinary team approach is essential for attaining a favorable outcome. All cases demonstrated good postoperative recovery and were successfully managed by removing the foreign body through its trajectory. We discuss and briefly review the literature on patterns, complications, and management issues of these less common injuries. ABBREVIATIONS: CN, cranial nerve CTA, computed tomographic angiography GCS, Glasgow Coma Scale PHI, penetrating head injury SOF, superior orbital fissure. © 2016 by the Congress of Neurological Surgeons. AD - Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China Department of Neurosurgery, Muhimbili Orthopedic and Neurosurgical Institute, Dar es Salaam, Tanzania AU - Mzimbiri, J. M. AU - Li, J. AU - Xia, Y. AU - Yuan, J. AU - Liu, J. AU - Liu, Q. DB - Scopus DO - 10.1227/NEU.0000000000001198 IS - 5 KW - Bamboo Brainstem Chopstick Foramen magnum Superior orbital fissure syndrome Transorbital Transpharyngeal M3 - Review N1 - Cited By :4 Export Date: 10 November 2020 PY - 2016 SP - E753-E760 ST - Surviving penetrating brainstem injury by bamboo sticks: Rare case reports and a brief review of literature T2 - Neurosurgery TI - Surviving penetrating brainstem injury by bamboo sticks: Rare case reports and a brief review of literature UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84955597014&doi=10.1227%2fNEU.0000000000001198&partnerID=40&md5=c96791fd2b59b462285ab38ea7ae9211 VL - 78 ID - 1183 ER - TY - JOUR AN - 4486833 AU - Woodcroft, R. DA - Dec DP - NLM ET - 1972/12/01 IS - 12 KW - Australia Bandages Foreign Bodies/etiology Needles Surgical Instruments Surgical Procedures, Operative/adverse effects Surveys and Questionnaires LA - eng N1 - Woodcroft, R Journal Article Australia Lamp. 1972 Dec;29(12):7-19. PY - 1972 SN - 0047-3936 (Print) SP - 7-19 ST - Survey into counting precautions in New South Wales operating theatres T2 - Lamp TI - Survey into counting precautions in New South Wales operating theatres VL - 29 ID - 1 ER - TY - JOUR AB - We present a case of retained intraocular lens (IOL) haptic segment in the anterior chamber, diagnosed seven months following a reportedly uneventful cataract surgery due to manifestation of inferior corneal edema. Specular microscopy revealed low endothelial counts of 513/mm2. Upon diagnosis, prompt surgical removal of the IOL haptic segment resulted in rapid resolution of the corneal edema within a week. Despite the clearing of the cornea, no improvement in the visual acuity occurred and cystoid macular edema was diagnosed and treated with topical anti-inflammatory agents and two intra-vitreal anti-VEGF injections, followed by complete resolution of ocular findings and improvement of the visual acuity. © 2014 Taylor & Francis. AD - Sheba Medical Center, Goldschleger Eye Institute, Tel Hashomer, 52621, Israel AU - Elyashiv, S. AU - Barequet, I. DB - Scopus DO - 10.3109/08820538.2013.874477 IS - 5-6 KW - Cornea edema haptic retained M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2015 SP - 450-453 ST - A Surprising Cause for Corneal Edema after Cataract Surgery: A Missed Posterior Chamber Intraocular Lens Haptic Remnant T2 - Seminars in Ophthalmology TI - A Surprising Cause for Corneal Edema after Cataract Surgery: A Missed Posterior Chamber Intraocular Lens Haptic Remnant UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84954078213&doi=10.3109%2f08820538.2013.874477&partnerID=40&md5=e88ec2ec08e632601cbc96ac64d2600f VL - 30 ID - 1215 ER - TY - JOUR AD - Department of Gastroenterology, Queen Elizabeth Hospital, Woolwich, London, United Kingdom AU - Taylor, K. M. AU - Foxton, M. AU - McNair, A. DB - Scopus DO - 10.1016/j.cgh.2009.09.028 IS - 3 M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2010 SP - e24-e25 ST - Surprise Finding at Endoscopic Retrograde Cholangiopancreatography T2 - Clinical Gastroenterology and Hepatology TI - Surprise Finding at Endoscopic Retrograde Cholangiopancreatography UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77349108785&doi=10.1016%2fj.cgh.2009.09.028&partnerID=40&md5=9b32049bd145e36c7956152d96be0cfa VL - 8 ID - 1466 ER - TY - JOUR AB - Unexpected clinical and/or imaging evidence of the recurrence of gastrointestinal stromal tumors soon after surgical resection may be complicated due to certain biological behavioral features of gastrointestinal stromal tumors. However, local hemostatic materials routinely used in abdominal surgery to achieve hemostasis intraoperatively may cause a foreign-body reaction, which appears to be indistinguishable from recurrent tumors in imaging studies. Thus, a second examination may be necessary to settle the true nature of the findings in such cases. If the resection and examination reveals a recurrent tumor, further proper oncological treatment is warranted, whereas if a foreign-body reaction is observed, radical or potentially harmful therapy may be withheld or cancelled. The present study retrospectively analyzes the case of an 83-year-old male patient who presented with a recurrent gastrointestinal stromal tumor four months after surgical resection, which was later identified as an intra-abdominal foreign-body granuloma caused by retained Surgicel® residue. The present study aimed to demonstrate why foreign-body granuloma induced by local hemostatic materials should be incorporated into the differential diagnosis of recurrent gastrointestinal stromal tumors post--operatively, particularly soon after surgical resection has been performed. AD - Department of Gastrointestinal Surgery, Su Bei People's Hospital of Jiangsu Province, Yangzhou University, Yangzhou, Jiangsu 225001, China AU - Wang, H. AU - Chen, P. DB - Scopus DO - 10.3892/ol.2013.1218 IS - 5 KW - Fludeoxyglucose (18F)-positron emission tomography-computed tomography Foreign-body granuloma Gastrointestinal stromal tumor recurrence Surgicelreg (oxidized regenerated cellulose) M3 - Article N1 - Cited By :14 Export Date: 10 November 2020 PY - 2013 SP - 1497-1500 ST - Surgicel® (oxidized regenerated cellulose) granuloma mimicking local recurrent gastrointestinal stromal tumor: A case report T2 - Oncology Letters TI - Surgicel® (oxidized regenerated cellulose) granuloma mimicking local recurrent gastrointestinal stromal tumor: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84875708603&doi=10.3892%2fol.2013.1218&partnerID=40&md5=13952baf9ba9d89f1538ae2ae1fbe0cb VL - 5 ID - 1307 ER - TY - JOUR AB - Purpose: The purpose of this study was to evaluate the anatomical and functional outcomes of surgical intervention in severely traumatized eyes with no light perception (NLP). Methods: In this prospective interventional case series, 18 eyes of 18 patients with severe ocular trauma whose vision was documented as NLP and with relative afferent pupillary defect of 3 to 4+ underwent deep vitrectomy and other appropriate procedures 1 to 3 times. Results: Vision was NLP in all eyes at the time of surgery, which was performed 3 days to 14 days after the initial trauma. During a mean follow-up period of 20.5 ± 5.2 months (range, 11-36 months), except for 1 case of phthisis, other eyes achieved acceptable anatomical and functional outcomes. Postoperative vision was NLP in 2 eyes (11.1%), light perception in 3 eyes (16.7%), hand motions in 4 eyes (22.2%), counting fingers in 3 eyes (16.7%), and 20/200 or better in 6 eyes (33.4%). Conclusion: After eye trauma, NLP vision and relative afferent pupillary defect of 3 to 4+ alone may not be an indication for enucleation. Performing exploratory surgery within 14 days after the injury may salvage the globe and improve vision; this approach also entails positive psychologic effects for patients and relatives. Copyright © by Ophthalmic Communications Society, Inc. AD - Department of Ophthalmology, Nikookari Eye Hospital, Tabriz Medical University, Nikookari Hospital-Abbasi Avenue, Tabriz 5154645395, Iran AU - Heidari, E. AU - Taheri, N. DB - Scopus DO - 10.1097/IAE.0b013e3181babd75 IS - 2 KW - No light perception Surgical treatment Traumatized eye M3 - Article N1 - Cited By :24 Export Date: 10 November 2020 PY - 2010 SP - 294-299 ST - Surgical treatment of severely traumatized eyes with no light perception T2 - Retina TI - Surgical treatment of severely traumatized eyes with no light perception UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-76749083826&doi=10.1097%2fIAE.0b013e3181babd75&partnerID=40&md5=7fc8e2ab289cc04a69504063242fdb3d VL - 30 ID - 1470 ER - TY - JOUR AN - 105789301. Language: English. Entry Date: 20080815. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 1 KW - Accountability Nursing Role Retained Instruments Surgical Sponges -- Classification Courts -- Ohio Damages, Legal Diverticulitis -- Surgery Evidence, Legal Ohio Physician's Role Postoperative Complications Surgical Count Procedure N1 - legal case. Journal Subset: Blind Peer Reviewed; Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Legal Case: Hodesh v. Korlitz, 2008-Ohio-2052 (05/02/2008). NLM UID: 100936959. PMID: NLM18686888. PY - 2008 SN - 1528-848X SP - 2-2 ST - Surgical towel left in pt.: were nurses responsible? T2 - Nursing Law's Regan Report TI - Surgical towel left in pt.: were nurses responsible? UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105789301&site=ehost-live&scope=site VL - 49 ID - 945 ER - TY - JOUR AB - The aim of the study was to conduct a qualitative exploration of the sociotechnical processes underlying retained surgical swabs, and to explore the fundamental reasons why the swab count procedure and related protocols fail in practice. Data was collected through a set of 27 semistructured qualitative interviews with scrub nurses from a large, multi-site teaching hospital. Interview transcripts were analysed using established constant comparative methods, moving between inductive and deductive reasoning. Key findings were associated with interprofessional perspectives, team processes and climate and responsibility for the swab count. The analysis of risk factors revealed that perceived social and interprofessional issues played a significant role in the reliability of measures to prevent retained swabs. This work highlights the human, psychological and organisational factors that impact upon the reliability of the process and gives rise to recommendations to address contextual factors and improve perioperative practice and training. AN - 24908834 AU - D'Lima, D. AU - Sacks, M. AU - Blackman, W. AU - Benn, J. DA - May DO - 10.1177/175045891402400503 DP - NLM ET - 2014/06/10 IS - 5 KW - Clinical Nursing Research Clinical Protocols Efficiency, Organizational Foreign Bodies Humans Interprofessional Relations Organizational Culture *Perioperative Nursing/organization & administration *Surgical Instruments LA - eng N1 - D'Lima, D Sacks, M Blackman, W Benn, J Journal Article Research Support, Non-U.S. Gov't England J Perioper Pract. 2014 May;24(5):103-11. doi: 10.1177/175045891402400503. PY - 2014 SN - 1750-4589 (Print) 1750-4589 SP - 103-11 ST - Surgical swab counting: a qualitative analysis from the perspective of the scrub nurse T2 - J Perioper Pract TI - Surgical swab counting: a qualitative analysis from the perspective of the scrub nurse VL - 24 ID - 151 ER - TY - JOUR AB - INTRODUCTION: Retained surgical sponge or other items in patients' bodies happens more frequently than is reported. Healthcare personnel can forget to remove textile material or instruments during complicated, extended, or emergency surgery. In addition, changes in the operating team can influence the occurrence of such errors. PRESENTATION OF CASE: We present a case with a symptomatic gossypiboma nine years after a previous cesarean section. A 34-year-old woman was admitted to the emergency room having experienced abdominal pain and fever for the previous month. An abdominal computed tomography revealed an abscess in the lower abdomen. A laparotomy was performed, and a resection and block were carried out. A surgical sponge was extracted from an omental abscess. DISCUSSION: Surgical sponges are the most common foreign materials retained (70%) in the abdominal cavity because of their frequent usage and small size. Moreover, a blood-soaked sponge in a hemorrhagic abdomen can be difficult to distinguish from blood. CONCLUSION: Whenever the accounting for material depends on humans, mistakes will continue to be committed. A falsely correct sponge count was reported in 71.42% of cases [14]; therefore, a new count system must be developed for post-surgical situations. AD - Department of Surgery, Assuta Medical Center, Tel Aviv, Israel. Electronic address: Sergio9@bezeqint.net. Assia Medical Group, Tel Aviv, Israel. Department of Nutrition and Diet, Assuta Medical Center, Tel Aviv, Israel. AN - 27770737 AU - Susmallian, S. AU - Raskin, B. AU - Barnea, R. C2 - PMC5078679 DO - 10.1016/j.ijscr.2016.10.026 DP - NLM ET - 2016/10/23 KW - Abdomen Bowel Patient safety Retained foreign body Surgery LA - eng N1 - 2210-2612 Susmallian, Sergio Raskin, Benjamin Barnea, Royi Journal Article Int J Surg Case Rep. 2016;28:296-299. doi: 10.1016/j.ijscr.2016.10.026. Epub 2016 Oct 14. PY - 2016 SN - 2210-2612 (Print) 2210-2612 SP - 296-299 ST - Surgical sponge forgotten for nine years in the abdomen: A case report T2 - Int J Surg Case Rep TI - Surgical sponge forgotten for nine years in the abdomen: A case report VL - 28 ID - 183 ER - TY - JOUR AD - S. Sempeles, PA, United States AU - Sempeles, S. DB - Embase DO - 10.1097/01.JCE.0000294892.43394.17 IS - 4 KW - accuracy Food and Drug Administration foreign body gossypiboma health care cost health economics human malpractice medical error note nurse patent radiofrequency radiography surgeon surgical equipment surgical sponge surgical sponge counting system surgical technique SmartSponge LA - English M3 - Note N1 - L47511518 2007-10-01 PY - 2007 SN - 0363-8855 SP - 128-129 ST - Surgical sponge counting system earns food and drug administration clearance T2 - Journal of Clinical Engineering TI - Surgical sponge counting system earns food and drug administration clearance UR - https://www.embase.com/search/results?subaction=viewrecord&id=L47511518&from=export http://dx.doi.org/10.1097/01.JCE.0000294892.43394.17 VL - 32 ID - 611 ER - TY - JOUR AB - Objectives: To evaluate the current practices regarding formal or informal implementation of individual elements of the World Health Organisation's Surgical Safety Checklist in tertiary care hospitals of Karachi and to establish a pre-checklist baseline to suggest a plan for implementation of the checklist. Methods: The qualitative knowledge-attitude-practice (KAP) survey was conducted from May 1, 2009 to January 31, 2010, during whch 103 surgeries were observed in 10 hospitals across Karachi based on simple stratified sampling. Initially, 15 tertiary care hospitals were selected, but response and consent was received from 10 of them. The WHO checklist was applied after some basic changes according to local needs and perspectives. The surgical teams were also observed for coordination and working harmony. The data was analysed on SPSS version 12 and statistical tests were applied accordingly. Results: Of the 103 surgeries observed, 13 (13.4%) patients did not confirm their identity, site of surgery or procedure. There was no concept of timeout in 91 (88.5%) cases, while in 52 (53.8%) cases, the anaesthetist did not ask for known allergy, and prophylaxis antibiotic was not given in 36 (37.5%) cases. In 20 (21.2%) cases, sponge, needle and instruments were not counted. Conclusion: The results suggest that the safety of surgical patients in the operating theaters in hospitals under review was far from satisfactory. Introduction of and adherence to a safety checklist would result in significant reduction in death and complication rate. AD - A. A. Toor, Hamdard College of Medicine and Dentistry, Hamdard University, Karachi, Pakistan AU - Toor, A. A. AU - Nigh-e-Mumtaz, S. AU - Syed, R. AU - Yousuf, M. AU - Syeda, A. DB - Embase Medline IS - 1 KW - allergy anesthesist antibiotic prophylaxis checklist health care survey human multicenter study needle operating room questionnaire review surgical equipment surgical patient surgical sponge surgical technique L1 - internal-pdf://3172686010/3939.pdf LA - English M3 - Review N1 - L368066923 2013-01-15 2013-01-23 PY - 2013 SN - 0030-9982 SP - 76-80 ST - Surgical safety practices in Pakistan T2 - Journal of the Pakistan Medical Association TI - Surgical safety practices in Pakistan UR - https://www.embase.com/search/results?subaction=viewrecord&id=L368066923&from=export VL - 63 ID - 491 ER - TY - JOUR AB - BACKGROUND: Posterior segment metallic intraocular foreign bodies (IOFBs) are a leading cause of visual morbidity and blindness, especially among young and middle-aged working populations. Here, we aimed to evaluate the surgical outcomes of the removal of such IOFBs that result from injuries. METHODS: In this retrospective study, 39 patients injured by metallic posterior segment IOFBs and who underwent primary repair procedures, vitrectomies, and IOFBs removal with or without procedures for traumatic cataract removal, scleral buckling and intraoperative tamponade application from January, 2008 to January, 2019. We analyzed the preoperative, intraoperative and postoperative related factors that affect the final visual outcomes. RESULTS: The mean age of the 39 patients was 40.51 ± 12.48 years with the male being predominent (100%).The mean preoperative vision measured 1.50 [Snellen Equivalent (SE), 20/645] ± 1.12 logMAR with the mean final vision measuring 0.93 (SE, 20/172) ± 1.09 logMAR. The related factors that were determined to affect the final visual outcomes included preoperative vision (P = 0.025), IOFB-related macula injuries (P = 0.001) and the development of postoperative complications (P = 0.005) especially retinal detachment (P = 0.002) with the mean final vision measuring 2.12 (SE, counting finger to hand motion) ±1.23 logMAR. Concerning the preoperative signs, the patients with preoperative endophthalmitis also obtained poor mean final vision measuring 1.30 (SE,20/400) ± 1.40 logMAR. CONCLUSION: IOFB-related macula injuries and postoperative retinal detachment were important related factors of poor final visual prognoses in cases involving posterior segment metallic IOFBs. Removing IOFB as early as possible may prevent preoperative endophthalmitis which could lead poor final visions even without significance. AD - Department of Ophthalmology, Kaohsiung Veterans General Hospital, 386, Ta-Chung 1st Road, Kaohsiung, 813, Taiwan, Republic of China. School of Medicine, National Yang-Ming University, Taipei, Taiwan, Republic of China. Department of Ophthalmology, Kaohsiung Veterans General Hospital, 386, Ta-Chung 1st Road, Kaohsiung, 813, Taiwan, Republic of China. ttwu0101@gmail.com. School of Medicine, National Yang-Ming University, Taipei, Taiwan, Republic of China. ttwu0101@gmail.com. AN - 32631275 AU - Peng, K. L. AU - Kung, Y. H. AU - Hsu, P. S. AU - Wu, T. T. C2 - PMC7339457 DA - Jul 6 DO - 10.1186/s12886-020-01535-5 DP - NLM ET - 2020/07/08 IS - 1 KW - Endophthalmitis Metallic intraocular foreign bodies Posterior segment Retinal detachment Scleral buckling Tamponade Vitrectomy LA - eng N1 - 1471-2415 Peng, Kai-Ling Orcid: 0000-0002-1531-5588 Kung, Ya-Hsin Hsu, Pyn-Sing Wu, Tsung-Tien Journal Article BMC Ophthalmol. 2020 Jul 6;20(1):267. doi: 10.1186/s12886-020-01535-5. PY - 2020 SN - 1471-2415 SP - 267 ST - Surgical outcomes of the removal of posterior segment metallic intraocular foreign bodies T2 - BMC Ophthalmol TI - Surgical outcomes of the removal of posterior segment metallic intraocular foreign bodies VL - 20 ID - 256 ER - TY - JOUR AB - Objective The aim of our study was to present our experience in dealing with a group of complicated accidentally swallowed foreign bodies (FBs) that need surgical treatment. Methods From 2003-2008 we treated five adult patients who presented with complications after FB ingestion. These cases were dealt with in the hospitals of The Royal Medical Services in Jordan and in field. Results The complications treated were perforation of bowel in two cases, intestinal obstruction two cases and migration of FB (needle) to the liver one case. The preoperative diagnosis was achieved only in the last case. Conclusion The complications of the ingested FBs increased when they were sharp, pointed or large, and because it usually happened unnoticed by the patient. Thus, preoperative diagnosis is difficult, despite the wide range of imaging methods used. Complications are usually dealt with during operation especially when the FB is radiolucent. AD - Department of General Surgery Royal Medical Services, Irbid, Jordan AU - Jarbou, S. M. DB - Scopus IS - 2 KW - Foreign body ingestion Intestinal perforation M3 - Article N1 - Export Date: 10 November 2020 PY - 2011 SP - 83-85 ST - Surgical intervention for swallowed gastrointestinal foreign bodies in adults T2 - Rawal Medical Journal TI - Surgical intervention for swallowed gastrointestinal foreign bodies in adults UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-80055036718&partnerID=40&md5=48c9638fef4202c2b3bfb6b7c15b546f VL - 36 ID - 1403 ER - TY - JOUR AD - M.S. Selvan, Department of Perioperative Enterprise, Unit 205, The University of Texas, Houston, TX, United States AU - Selvan, M. S. AU - Skibber, J. M. AU - Walsh, G. L. DB - Embase Medline DO - 10.1016/j.jss.2008.01.033 IS - 1 KW - editorial foreign body medical error medical literature nomenclature postoperative period priority journal surgical equipment LA - English M3 - Editorial N1 - L50085912 2008-11-04 PY - 2008 SN - 0022-4804 1095-8673 SP - 1-2 ST - The Surgical Instrument Counting Process: A Statistician's Plea for Terminology Clarification T2 - Journal of Surgical Research TI - The Surgical Instrument Counting Process: A Statistician's Plea for Terminology Clarification UR - https://www.embase.com/search/results?subaction=viewrecord&id=L50085912&from=export http://dx.doi.org/10.1016/j.jss.2008.01.033 VL - 150 ID - 590 ER - TY - JOUR AB - Poster Presentation Purpose for the Program An opportunity existed to reduce or eliminate the risk of retained surgical items (RSIs) in response to the Joint Commission's October Sentinel Event Alert regarding RSIs. Within perinatal nursing there is a keen awareness that a discrepancy exists between the approaches to surgical counts in the perioperative suite versus the vaginal delivery room. It is very likely that during vaginal births, the surgical count error rate is greater than the overall 10% to 15% error rate noted by The Joint Commission. Proposed Change To implement a highly reliable and standardized count process during all vaginal births that was more in line with structured counts of the perioperative suites. Implementation, Outcomes, and Evaluation Although limited, the literature demonstrated the need to first revise the facility wide count policy and specifically address the count process for vaginal births. Next, informal staff surveys indicated that the existing process lacked clear expectations, identified significant gaps in the process, and confirmed breaks in communication between nursing and provider staff. These surveys also revealed that the team approached the counts for vaginal births in a less formal manner than the surgical counts in the perioperative suite. Based on this information we implemented a standardized counting system that included a defined interdisciplinary communication requisite, streamlined the documentation, and provided global team education. Within 2 months of the completion of phase one training (hands on training) and the policy revision, the count sheet audits demonstrated greater than 95% adherence. After Phase 2 training, which included video demonstration and eLearning, greater than 98% adherence was demonstrated using 100% count sheet and random observed audits. In the 3rd and 4th month of observed audits, 100% adherence was noted, demonstrating normalization of the new process. Implications for Nursing Practice Primary outcomes included improved communication between health care providers and nurses, count diligence, and standardization of the count culture within the vaginal delivery room. In addition, the process change enhanced patient safety by minimizing the risk of the RSI in the vaginal delivery room. Finally, although not utilized in this process change, there is clearly a need to evaluate the effect of assistive safe count technology during vaginal births. AD - St. David's North Austin Medical Center St. David's Women's Center of Texas AN - 109793675. Language: English. Entry Date: 20150609. Revision Date: 20200708. Publication Type: Journal Article AU - Hurley, Tonnyann T. AU - Meyer, Amy DB - ccm DO - 10.1111/1552-6909.12664 DP - EBSCOhost KW - Surgical Count Procedure Retained Instruments -- Prevention and Control -- In Pregnancy Delivery Rooms Pregnancy Female Vaginal Birth Obstetric Nursing Hospital Policies Staff Development Professional Compliance Patient Safety Communication Surgical Sponges N1 - abstract. Supplement Title: Jun2015 Supplement. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Special Interest: Obstetric Care; Patient Safety; Pediatric Care; Women's Health. NLM UID: 8503123. PY - 2015 SN - 0884-2175 SP - S8-S8 ST - Surgical Counts in the Delivery Room...Proceedings of the 2015 AWHONN Convention T2 - JOGNN: Journal of Obstetric, Gynecologic & Neonatal Nursing TI - Surgical Counts in the Delivery Room...Proceedings of the 2015 AWHONN Convention UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109793675&site=ehost-live&scope=site VL - 44 ID - 878 ER - TY - JOUR AB - Purpose for the Program: An opportunity existed to reduce or eliminate the risk of retained surgical items (RSIs) in response to the Joint Commission's October Sentinel Event Alert regarding RSIs. Within perinatal nursing there is a keen awareness that a discrepancy exists between the approaches to surgical counts in the perioperative suite versus the vaginal delivery room. It is very likely that during vaginal births, the surgical count error rate is greater than the overall 10% to 15% error rate noted by The Joint Commission. Proposed Change: To implement a highly reliable and standardized count process during all vaginal births that was more in line with structured counts of the perioperative suites. Implementation, Outcomes, and Evaluation: Although limited, the literature demonstrated the need to first revise the facility wide count policy and specifically address the count process for vaginal births. Next, informal staff surveys indicated that the existing process lacked clear expectations, identified significant gaps in the process, and confirmed breaks in communication between nursing and provider staff. These surveys also revealed that the team approached the counts for vaginal births in a less formal manner than the surgical counts in the perioperative suite. Based on this information we implemented a standardized counting system that included a defined interdisciplinary communication requisite, streamlined the documentation, and provided global team education. Within 2 months of the completion of phase one training (hands on training) and the policy revision, the count sheet audits demonstrated greater than 95% adherence. After Phase 2 training, which included video demonstration and eLearning, greater than 98% adherence was demonstrated using 100% count sheet and random observed audits. In the 3rd and 4th month of observed audits, 100% adherence was noted, demonstrating normalization of the new process. Implications for Nursing Practice: Primary outcomes included improved communication between health care providers and nurses, count diligence, and standardization of the count culture within the vaginal delivery room. In addition, the process change enhanced patient safety by minimizing the risk of the RSI in the vaginal delivery room. Finally, although not utilized in this process change, there is clearly a need to evaluate the effect of assistive safe count technology during vaginal births. © 2015 AWHONN, the Association of Women's Health, Obstetric and Neonatal Nurses AD - St. David's North Austin Medical Center, Austin, TX, United States St. David's Women's Center of Texas, Austin, TX, United States AU - Hurley, T. T. AU - Meyer, A. DB - Scopus DO - 10.1111/1552-6909.12664 KW - retained surgical items surgical counts vaginal birth M3 - Article N1 - Export Date: 10 November 2020 PY - 2015 SP - S8 ST - Surgical Counts in the Delivery Room T2 - JOGNN - Journal of Obstetric, Gynecologic, and Neonatal Nursing TI - Surgical Counts in the Delivery Room UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85044862175&doi=10.1111%2f1552-6909.12664&partnerID=40&md5=da0b23e5262bbd1ddc115a4f36928fdd VL - 44 ID - 1227 ER - TY - JOUR AB - INTRODUCTION: Counting of accountable items used during surgery, frequently called 'the count', is a fundamental practice to ensure that items such as surgical instruments, sponges and sharps are not forgotten within patients. Although inadvertently leaving behind a sponge or instrument at the end of an operation is a rare event, it is an error that may have serious implications. OBJECTIVES: The aim of this evidence implementation project was to contribute to promoting evidence-based practice in surgical counts in open abdominal and pelvic surgeries and thereby improving the outcomes of the surgical patients at a surgical centre of a university hospital. METHODS: The current evidence implementation project used the JBI Practical Application of Clinical Evidence System and Getting Research into Practice (GRiP) audit and feedback tool. The JBI Practical Application of Clinical Evidence System and GRiP framework for promoting evidence-based healthcare involves three phases of activity: first, establishing a project team and undertaking a baseline audit based on evidence-informed criteria; second, reflecting on the results of the baseline audit and designing and implementing strategies to address non-compliance found in the baseline audit informed by the JBI GRiP framework; third, conducting a follow-up audit to assess the outcomes of the interventions implemented to improve practice, and identify future practice issues to be addressed in subsequent audits. These three phases were performed over a period of 6 months, from August 2017 to March 2018. RESULTS: The baseline audit revealed deficits between old and best practice in all criteria. Barriers for implementation of a protocol for surgical counts were identified, and strategies were implemented. The postimplementation (follow-up) audit showed improvement in compliance with best practice in six of the audit criteria selected except two, a multidisciplinary team approach to decrease retained surgical items, and limited staff hand-offs during surgical procedures to ensure the same team is present in all counting episodes. CONCLUSION: The main achievements of the study included substantial increases in compliance with best practice. However, registration and report and commitment of all members of surgical team to apply the entire protocol, avoiding to skip any step, persist as challenges. AD - Clinics Hospital of the Federal University of Pernambuco, Recife. The Brazilian Centre for Evidence-informed Healthcare: A Joanna Briggs Institute Centre of Excellence. School of Nursing, University of São Paulo, São Paulo, Brazil. University Hospital, University of São Paulo. AN - 33038110 AU - Gomes, E. T. AU - Galvão, M. C. B. AU - Shimoda, G. T. AU - de Oliveira, L. B. AU - de Araújo Püschel, V. A. DA - Sep 21 DO - 10.1097/xeb.0000000000000253 DP - NLM ET - 2020/10/11 LA - eng N1 - 1744-1609 Gomes, Eduardo T Galvão, Mayana C B Shimoda, Gilcéria T de Oliveira, Larissa B de Araújo Püschel, Vilanice A Journal Article Australia Int J Evid Based Healthc. 2020 Sep 21. doi: 10.1097/XEB.0000000000000253. PY - 2020 SN - 1744-1595 ST - Surgical counts in open abdominal and pelvic surgeries in a university hospital: a best practice implementation project T2 - Int J Evid Based Healthc TI - Surgical counts in open abdominal and pelvic surgeries in a university hospital: a best practice implementation project ID - 264 ER - TY - JOUR AB - The surgical count plays a vital role in enabling perioperative nurses to provide a safe environment to surgical patients. Counting errors are preventable. Although national standards of care provide excellent guidelines for developing effective count protocols, counting procedures are often modified according to individual health care policy. This article will discuss the risk factors for retained items, rate of occurrence, what objects are being left in patients, role of x-rays and consequences of leaving an object in a patient. It will also highlight points to be considered when implementing new count policies. AD - Health Sciences Centre, Winnipeg, MB. AN - 15709630 AU - Porteous, J. DA - Dec DP - NLM ET - 2005/02/16 IS - 4 KW - Canada Foreign Bodies/diagnostic imaging/epidemiology/etiology/*prevention & control Humans Intraoperative Complications/diagnostic imaging/epidemiology/etiology/*prevention & control Male Medical Errors/nursing/*prevention & control/statistics & numerical data Middle Aged *Nurse's Role Operating Room Nursing/*organization & administration Operating Rooms/organization & administration Organizational Policy Practice Guidelines as Topic Radiography Risk Factors Safety Management/organization & administration Surgical Sponges/*adverse effects United States LA - eng N1 - Porteous, Joan Case Reports Journal Article Review Canada Can Oper Room Nurs J. 2004 Dec;22(4):6-8, 10, 12. PY - 2004 SN - 0712-6778 (Print) 0712-6778 SP - 6-8, 10, 12 ST - Surgical counts can be risky business! T2 - Can Oper Room Nurs J TI - Surgical counts can be risky business! VL - 22 ID - 51 ER - TY - JOUR AB - The Australian College of Perioperative Nurses (ACORN) have developed a set of standards to guide clinical practice within the perioperative setting. The ACORN standard 'Management of accountable items used during surgery and procedures' (ACORN 2016) details a process for perioperative nurses to follow when undertaking a surgical count. AN - 29280599 AU - Warwick, V. AU - Gillespie, B. DA - May DP - NLM ET - 2017/12/28 IS - 10 KW - Foreign Bodies/*prevention & control Humans Medical Errors/*prevention & control *Nurse's Role *Operating Room Nursing *Patient Safety LA - eng N1 - Warwick, Vicky Gillespie, Brigid Journal Article Australia Aust Nurs Midwifery J. 2017 May;24(10):39. PY - 2017 SN - 2202-7114 (Print) 2202-7114 SP - 39 ST - SURGICAL COUNTING: A PERIOPERATIVE NURSE'S PERSPECTIVE T2 - Aust Nurs Midwifery J TI - SURGICAL COUNTING: A PERIOPERATIVE NURSE'S PERSPECTIVE VL - 24 ID - 204 ER - TY - JOUR AN - 105523246. Language: English. Entry Date: 20090515. Revision Date: 20150711. Publication Type: Journal Article AU - Hepper, K. DA - 2008 Spring DB - ccm DP - EBSCOhost IS - 3 KW - Perioperative Nursing -- Standards Surgical Count Procedure -- Standards N1 - abstract. Journal Subset: Australia & New Zealand; Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. PY - 2008 SN - 1448-7535 SP - 38-38 ST - The surgical count: standards and developments T2 - ACORN: The Journal of Perioperative Nursing in Australia TI - The surgical count: standards and developments UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105523246&site=ehost-live&scope=site VL - 21 ID - 930 ER - TY - JOUR AB - OBJECTIVE: To analyze the surgical count process according to reports of nurses working in surgical centers of a city in the state of São Paulo. METHODS: Cross-sectional study with a sample of 55 nurses. Data collection occurred from August to December 2013, with application of an instrument submitted to face and content validation, composed of data on variables regarding characteristics of nurses, hospital, and surgical count process. RESULTS: Fifty-two (94.5%) nurses reported that the surgical count process was carried out in their workplaces. A statistically significant association was found between the surgical count process and the type of institution (P=0.046), and between the presence of a surgical technologist and the processes for counting surgical instruments (P<0.001) and sponges (P=0.016). CONCLUSION: The results found contributed to understand how, by whom, and when the surgical count process was carried out in the studied hospital. AD - Universidade Federal de Alfenas (UNIFAL), Escola de Enfermagem. Alfenas, Minas Gerais, Brasil. Universidade de São Paulo (USP), Escola de Enfermagem de Ribeirão Preto. Ribeirão Preto, São Paulo, Brasil. AN - 28273256 AU - Freitas, P. S. AU - Mendes, K. D. AU - Galvão, C. M. DA - Feb 23 DO - 10.1590/1983-1447.2016.04.66877 DP - NLM ET - 2017/03/09 IS - 4 KW - Cross-Sectional Studies Foreign Bodies/*prevention & control Humans *Patient Safety Surgical Instruments/*statistics & numerical data LA - por eng N1 - Freitas, Patrícia Scotini Mendes, Karina Dal Sasso Galvão, Cristina Maria Journal Article Brazil Rev Gaucha Enferm. 2017 Feb 23;37(4):e66877. doi: 10.1590/1983-1447.2016.04.66877. OP - Processo de contagem cirúrgica: evidências para a segurança do paciente. PY - 2017 SN - 0102-6933 (Print) 0102-6933 SP - e66877 ST - Surgical count process: evidence for patient safety T2 - Rev Gaucha Enferm TI - Surgical count process: evidence for patient safety VL - 37 ID - 192 ER - TY - JOUR AB - AIMS AND OBJECTIVES: To analyse the evidence reported in the literature concerning the surgical count process for surgical sponges, surgical instruments and sharps and to identify knowledge gaps for future research on the surgical count process. BACKGROUND: The surgical count process stands out among the practices advocated by the World Health Organization to ensure surgical safety. The literature indicates that this practice should be performed in all surgical processes. However, surgical items are still retained. DESIGN: Integrative review. METHODS: The literature search was conducted in the PubMed, CINAHL and LILACS databases and included studies on the surgical count process published in English, Spanish and Portuguese from January 2003-December 2013. RESULTS: A total of 28 primary studies were included in the sample, allowing the knowledge on the surgical count process to be summarised and grouped into three categories: risk factors for retained surgical items, how the surgical count process should be performed in the intraoperative period and the accompanying technologies that collaborate to improving the manual count process. CONCLUSIONS: The correct implementation of the surgical count process by the perioperative nurse may contribute to preventing retained surgical items, thereby improving surgical patient safety. RELEVANCE TO CLINICAL PRACTICE: Nurses can use this review to assist in decision-making directed towards preparing, updating and implementing a reliable system for the surgical count process based on recent evidence because the perioperative nurse plays a key role in the implementation of this practice in health services. AD - Pythagoras University of Poços de Caldas, Poços de Caldas, SP, Brazil. University of São Paulo at Ribeirão Preto College of Nursing, Ribeirão Preto, SP, Brazil. Faculty of Nursing, University of Alberta, Edmonton, AB, Canada. AN - 27104785 AU - Freitas, P. S. AU - Silveira, R. C. AU - Clark, A. M. AU - Galvão, C. M. DA - Jul DO - 10.1111/jocn.13216 DP - NLM ET - 2016/04/23 IS - 13-14 KW - Foreign Bodies/*prevention & control Humans Medical Errors/prevention & control *Patient Safety Perioperative Nursing Practice Guidelines as Topic Surgical Procedures, Operative/*nursing Brazil evidence-based practice integrative review patient safety retained surgical items sharps surgical count process surgical instruments surgical sponges LA - eng N1 - 1365-2702 Freitas, Patrícia Scotini Silveira, Renata Cristina de Campos Pereira Clark, Alexander Michael Galvão, Cristina Maria Journal Article Review England J Clin Nurs. 2016 Jul;25(13-14):1835-47. doi: 10.1111/jocn.13216. Epub 2016 Apr 22. PY - 2016 SN - 0962-1067 SP - 1835-47 ST - Surgical count process for prevention of retained surgical items: an integrative review T2 - J Clin Nurs TI - Surgical count process for prevention of retained surgical items: an integrative review VL - 25 ID - 177 ER - TY - JOUR AB - Validating existing count practices and reducing individual practice variance are necessary to decrease the risk for retained surgical items. A quality improvement project was undertaken at one large city hospital to identify best practice and eliminate variability in count practices. The project included an analysis of 20 surgical count policies from hospitals across the country and a review of count practices among nurses and surgical technologists at the facility. Assessment of the policies and practices indicated that clinical practice requirements in the policies varied greatly, and there was a high degree of count practice variability among staff members. The facility OR manager and OR quality coordinator collaborated with staff nurses and surgical technologists to identify practices that created variability and then addressed each one to create a new count policy and reduce the risk of retained surgical items. AD - St Luke’s Episcopal Hospital, Houston, Texas, USA. AN - 22283914 AU - Edel, E. M. DA - Feb DO - 10.1016/j.aorn.2011.02.014 DP - NLM ET - 2012/01/31 IS - 2 KW - Foreign Bodies/*prevention & control Hospitals, Urban/standards Humans Medical Errors/*prevention & control Needles Patient Safety/standards Perioperative Nursing/*methods/standards *Practice Guidelines as Topic Surgical Instruments Surgical Procedures, Operative/*methods/nursing/standards LA - eng N1 - 1878-0369 Edel, Elizabeth Morell Journal Article United States AORN J. 2012 Feb;95(2):228-38. doi: 10.1016/j.aorn.2011.02.014. PY - 2012 SN - 0001-2092 SP - 228-38 ST - Surgical count practice variability and the potential for retained surgical items T2 - Aorn j TI - Surgical count practice variability and the potential for retained surgical items VL - 95 ID - 123 ER - TY - JOUR AB - Purpose: Foreign bodies as the nucleus for formation of gallstones are not frequently seen as the cause of choledocholithiasis. We present a case of a surgical clip applied across the cystic duct during laparoscopic cholecystectomy, which subsequently migrated into the common bile duct. This clip resulted in choledocholithiasis and subsequent cholangitis just one year after cholecystectomy. Methods: A 41-year-old female with past medical history of GERD, hypertension, and alcohol abuse presents with complaints of persistent right upper quadrant pain and fever for one week. Physical exam was notable for right upper quadrant and epigastric tenderness, and was otherwise unremarkable. Laboratory findings demonstrated a WBC of 12.5 x 103, AST/ALT ratio of 615/409, alkaline phosphatase of 484 and total bilirubin of 2.1 with direct bilirubin of 1.1. Computerized tomography (CT) scan revealed dilation of the biliary tree with two surgical clips observed in the gallbladder fossa and one clip appreciated within the lumen of the distal common bile duct. The patient was diagnosed with acute cholangitis in the setting of choledocolithiasis. Results: The patient was started on empiric piperacillin/tazobactam and Endoscopic Retrograde Cholangiopancreatography (ERCP) was scheduled. Upon cannulation of the papilla using an Ultratome sphinctertome over a 0.035in Jagwire, extrusion of frank pus was appreciated. A cholangiogram revealed a dilated intrahepatic duct and a filling defect in the distal CBD with a central fluoroscopic “line” through the defect representing the surgical clip. The cystic duct with two surgical clips attached was also noted. A generous sphincterotomy was performed and bile duct sweep using a retrieval wire basket extruded a pigmeted stone with a surgical clip at its core. Subsequent retrieval balloon sweeps of the CBD with cholangiogram revealed no further filling defects. A 7 Fr 7cm straight plastic biliary stent was placed with drainage of clear bile. The patient's white count and liver function tests normalized, and the patient was discharged home. Conclusion: Any foreign bodies in the biliary tract, including non-absorbable surgical clips, can serve as the substrate for stone formation. For those patients who have undergone cholecystectomy, clip migration should be considered as a cause of recurrent pain in the right upper quadrant. AD - N. Karanth, Lenox Hill Hospital, Hauppauge, NY, United States AU - Karanth, N. AU - Sonpal, N. AU - Zlatanic, J. AU - Haber, G. DB - Embase DO - 10.1038/ajg.2010.320-7 KW - bilirubin glucuronide fenamisal plastic bilirubin alkaline phosphatase common bile duct stone stone formation college gastroenterology clip human patient cholecystectomy cholangiography cholangitis cystic duct pain foreign body common bile duct computer assisted tomography bile liver function test tree bile duct laboratory sphincterotomy fever pus cannulation endoscopic retrograde cholangiopancreatography alcohol abuse hypertension medical history gallstone stent female hepatobiliary system gallbladder LA - English M3 - Conference Abstract N1 - L70825421 2012-08-10 PY - 2010 SN - 0002-9270 SP - S217 ST - Surgical clip as the nidus for common bile duct stone formation: A very rare cause for a common condition T2 - American Journal of Gastroenterology TI - Surgical clip as the nidus for common bile duct stone formation: A very rare cause for a common condition UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70825421&from=export http://dx.doi.org/10.1038/ajg.2010.320-7 VL - 105 ID - 554 ER - TY - JOUR AB - The article reports on a successful initiative which was implemented at Boston Children's Hospital in Boston, Massachusetts to reduce the number of patients with retained surgical items following surgery and reduce incorrect item counts and count discrepancies in the hospital's operating room. AN - 76912434. Language: English. Entry Date: 20121016. Revision Date: 20190620. Publication Type: Article. Journal Subset: Biomedical DB - ccm DP - EBSCOhost IS - 7 KW - Surgicenters -- Administration Health Care Errors -- Prevention and Control Surgical Count Procedure Operating Rooms -- Administration Surgical Equipment and Supplies Staff Development Retained Instruments -- Prevention and Control N1 - Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2012 SN - 0190-5066 SP - 73-74 ST - Surgery staff reduces count problems by 50% T2 - Same-Day Surgery TI - Surgery staff reduces count problems by 50% UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=76912434&site=ehost-live&scope=site VL - 36 ID - 825 ER - TY - JOUR AD - A.D. Tammelleo AU - Tammelleo, A. D. DB - Medline IS - 2 KW - article case report human legal aspect legal liability male operating room personnel surgery surgical sponge United States LA - English M3 - Article N1 - L127311983 1997-10-01 PY - 1997 SN - 0034-3196 SP - 2 ST - The surgeon's nondelegable responsibility for the sponge count. Case on point: Johnston v. Southwest Louisiana Assn. 693 So. 2d 1195-LA (1997) T2 - The Regan report on nursing law TI - The surgeon's nondelegable responsibility for the sponge count. Case on point: Johnston v. Southwest Louisiana Assn. 693 So. 2d 1195-LA (1997) UR - https://www.embase.com/search/results?subaction=viewrecord&id=L127311983&from=export VL - 38 ID - 661 ER - TY - JOUR AB - Purpose. Surfboard-related eye injuries are increasingly being reported. There is little clinical or radiological information of injuries with retained intraorbital foreign bodies. To our knowledge, this is the largest case series of such patients and the first description of a surfboard fibreglass foreign body misreported as a displaced bone fragment. Methods. Retrospective case series of surfboardrelated eye injuries with intraorbital foreign bodies collected from tertiary ophthalmology centres in Sydney, Australia. Results. Three male patients with an average age of 43 years presented with blunt orbital trauma from the nose of a surfboard. Visual acuity was comparable to baseline in two patients and count fingers in the third. All patients had proptosis, no evidence of penetrating ocular injury and no posterior segment pathology. Two patients had sluggish pupillary responses requiring urgent lateral canthotomy. CT imaging was performed in all patients. A fibreglass intraorbital foreign body of 1165 Hounsfield units was misreported as a displaced orbital wall fragment in one patient. Foreign bodies were correctly reported in remaining patients. All patients underwent surgical exploration, foreign body extraction and lacrimal apparatus/skin repair with no subsequent oculoplastic or visual sequelae. Conclusion. Surfboard-related eye injuries may involve retained intraorbital foreign bodies. Fibreglass used in surfboard construction has a similar radiological appearance and density to bone on CT imaging thus may be misinterpreted as a bone fragment. A high suspicion for fibreglass foreign bodies should be exercised in orbital surfboard injuries. AD - V. Leung, Royal North Shore Hospital, Sydney, Australia AU - Leung, V. AU - Beshay, N. AU - Dunn, H. AU - Smith, J. AU - O'Donnell, B. DB - Embase DO - 10.1111/ceo.13054/full KW - adult Australia case report case study complication exophthalmos extraction eye injury finger foreign body human lacrimal apparatus male nose ophthalmology orbit injury pathology retrospective study skin surgery visual acuity LA - English M3 - Conference Abstract N1 - L619284906 2017-11-21 PY - 2017 SN - 1442-9071 SP - 119 ST - Surfboard-related intraorbitalforeign bodies - A case series and adiological considerations T2 - Clinical and Experimental Ophthalmology TI - Surfboard-related intraorbitalforeign bodies - A case series and adiological considerations UR - https://www.embase.com/search/results?subaction=viewrecord&id=L619284906&from=export http://dx.doi.org/10.1111/ceo.13054/full VL - 45 ID - 363 ER - TY - JOUR AB - Implant-mediated fibrotic reactions are detrimental to the performance of encapsulated cells, implanted drug release devices, and sensors. To improve the implant function and longevity, recent research has emphasized the need for inducing alterations in cellular responses. Although material surface functional groups have been shown to be potent in affecting cellular activity in vitro and short-term in vivo responses, these groups appear to have little influence on long-term in vivo fibrotic reactions, possibly as a result of insufficient interactions between recruited host cells and functional groups on the implants. To maximize the influence of functionality on cells, and to mimic drug release microspheres, functionalized micronsized particles were created and tested for their ability in modulating tissue responses to biomaterial implants. In this work, the surfaces of polypropylene particles were controllably coated with four different functional groups, specifically -OH, -NH2, -CF x, and -COOH, using a radio frequency glow discharge plasma polymerization technique. The effect of these surface functionalities on host tissue responses were then evaluated using a mice subcutaneous implantation model. Major differences were observed in contrasting tissue response to the different chemistries. Surfaces with -OH and -NH2 surface groups induced the thickest fibrous capsule accompanied with the greatest cellular infiltration into the implants. In contrast, surfaces with -CFx and -COOH exhibited the least inflammatory/fibrotic responses and cellular infiltrations. The present results clearly demonstrate that, by increasing the available functionalized surface area and spatial distribution, the effect of surface chemistry on tissue reactivity can be substantially enhanced. © 2007 Wiley Periodicals, Inc. AD - Bioengineering Department, University of Texas at Arlington, P.O. Box 19138, Arlington, TX 76019-0138, United States Chemistry and Biochemistry Department, University of Texas at Arlington, P.O. Box 19065, Arlington, TX 76019-0065, United States Biomedical Engineering Program, University of Texas at Arlington, P.O. Box 19138, Arlington, TX 76019-0138, United States AU - Kamath, S. AU - Bhattacharyya, D. AU - Padukudru, C. AU - Timmons, R. B. AU - Tang, L. DB - Scopus DO - 10.1002/jbm.a.31649 IS - 3 KW - Fibrosis Inflammation Microsphere Plasma polymerization Surface modification M3 - Article N1 - Cited By :76 Export Date: 10 November 2020 PY - 2008 SP - 617-626 ST - Surface chemistry influences implant-mediated host tissue responses T2 - Journal of Biomedical Materials Research - Part A TI - Surface chemistry influences implant-mediated host tissue responses UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-49149131177&doi=10.1002%2fjbm.a.31649&partnerID=40&md5=a1c8168aafb2cac31163f2ab28375332 VL - 86 ID - 1518 ER - TY - JOUR AB - Gossypiboma or retained surgical sponge is an infrequently encountered surgical complication, more so in the head and neck region. A literature search did not reveal a previously reported case of retained or concealed surgical sponge after microscopic ear surgery. We present a unique and previously unreported case of a 25-year-old male who presented with a cystic swelling in the right supra-aural region 5 months post-modified radical mastoidectomy of the right ear. Surgical excision of the swelling revealed a retained surgical sponge. We emphasise the importance of counting surgical sponges after every surgical step to minimise the incidence of such retained surgical items. AD - Dr. Shroff's Charity Eye Hospital, Department of ENT , New Delhi , India. AN - 27502345 AU - Chawla, N. AU - Gupta, N. AU - Dhawan, N. C2 - PMC5392885 DA - Nov DO - 10.1308/rcsann.2016.0234 DP - NLM ET - 2016/10/30 IS - 8 KW - Adult *Ear, Inner/surgery Foreign Bodies/*etiology/surgery Humans Male Mastoid/surgery Medical Errors/*adverse effects Surgical Sponges/*adverse effects Gossypiboma Retained surgical item Supra-aural Surgical sponge LA - eng N1 - 1478-7083 Chawla, N Gupta, N Dhawan, N Case Reports Journal Article Ann R Coll Surg Engl. 2016 Nov;98(8):e186-e188. doi: 10.1308/rcsann.2016.0234. Epub 2016 Aug 9. PY - 2016 SN - 0035-8843 (Print) 0035-8843 SP - e186-e188 ST - Supra-aural gossypiboma: case report of a retained textile surgical sponge in an unusual location T2 - Ann R Coll Surg Engl TI - Supra-aural gossypiboma: case report of a retained textile surgical sponge in an unusual location VL - 98 ID - 184 ER - TY - JOUR AB - Objective. Medical implants made of non-biological materials provoke a chronic inflammatory response, resulting in the deposition of a collagenous scar tissue (ST) layer on their surface, that gradually thickens over time. This is a critical problem for neural interfaces. Scar build-up on electrodes results in a progressive decline in signal level because the scar tissue gradually separates axons away from the recording contacts. In regenerative sieves and microchannel electrodes, progressive scar deposition will constrict and may eventually choke off the sieve hole or channel lumen. Interface designs need to address this issue if they are to be fit for long term use. This study examines a novel method of inhibiting the formation and thickening of the fibrous scar. Approach. Research to date has mainly focused on methods of preventing stimulation of the foreign body response by implant surface modification. In this paper a pharmacological approach using drug elution to suppress chronic inflammation is introduced. Microchannel implants made of silicone doped with the steroid drug dexamethasone were implanted in the rat sciatic nerve for periods of up to a year. Tissue from within the microchannels was compared to that from control devices that did not release any drug. Main results. In the drug eluting implants the scar layer was significantly thinner at all timepoints, and unlike the controls it did not continue to thicken after 6 months. Control implants supported axon regeneration well initially, but axon counts fell rapidly at later timepoints as scar thickened. Axon counts in drug eluting devices were initially much lower, but increased rather than declined and by one year were significantly higher than in controls. Significance. Drug elution offers a potential long term solution to the problem of performance degradation due to scarring around neural implants. © 2016 IOP Publishing Ltd. AD - Nuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, United Kingdom AU - Fitzgerald, J. J. C7 - 026006 DB - Scopus DO - 10.1088/1741-2560/13/2/026006 IS - 2 KW - bioengineering drug release neural interfacing M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2016 ST - Suppression of scarring in peripheral nerve implants by drug elution T2 - Journal of Neural Engineering TI - Suppression of scarring in peripheral nerve implants by drug elution UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84962359475&doi=10.1088%2f1741-2560%2f13%2f2%2f026006&partnerID=40&md5=6b6b4753acd38f94cac80f24d7d16c90 VL - 13 ID - 1193 ER - TY - JOUR AB - Background: Major depressive disorder is one of the most common psychiatric illnesses. It is counted as an important suicide-attempting factor. Beside common and known suicide methods such as pesticide poisoning and hanging, some unusual methods (adapted by major depressive disorder patients) are reported in the literature. One of these methods is intracranial swing needle insertion. Case presentation: Hereby, we detail a 44-year-old woman who was admitted to our hospital due to a sewing needle in her brain tissue. The first sign suggesting the existence of a metal foreign body in her brain was the rejection of magnetic resonance imaging ordered (follow-up of a previous admission). Later, a sewing needle was observed in her skull inserted in a suicidal attempt. Her denial of the attempt has aroused the medical team attention to make further study of the patient from a psychiatric point of view. The psychiatric study expressed major depressive disorder in the patient which can justify her suicide intention in the needle insertion. Conclusions: Treating such patients should be tackled in two fronts. From neurosurgical point of view, it should be decided whether to extract the foreign body or conduct a follow-up in order to determine the necessary time for operation. On the other hand, from a psychiatric point of view, rigorous consult sessions with patient and family members are required to prevent recurrence of such attempts. © 2020, The Author(s). AD - Department of Neurosurgery, Shiraz University of Medical Science, Shiraz, Iran Department of Pediatrics, Namazi Hospital, Shiraz University of Medical Science, Namazi Square, Shiraz, 71937–11351, Iran Department of Psychiatry, Shiraz University of Medical Science, Shiraz, Iran AU - Derakhshan, N. AU - Yaghamei, S. AU - Mostafeenezhad, N. C7 - 33 DB - Scopus DO - 10.1186/s43045-020-00042-z IS - 1 KW - Case report Intracranial sewing needle Major depressive disorder Rare suicidal attempt M3 - Article N1 - Export Date: 10 November 2020 PY - 2020 ST - Suicidal attempt with intracranial sewing needle in a female adult with major depressive disorder, case report T2 - Middle East Current Psychiatry TI - Suicidal attempt with intracranial sewing needle in a female adult with major depressive disorder, case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85089531288&doi=10.1186%2fs43045-020-00042-z&partnerID=40&md5=5b348862d679207d059a9e7062e67d03 VL - 27 ID - 948 ER - TY - JOUR AB - Background and Goal of Study: Our hospital has a total of 13 in-patient theatres and we report on a one year audit of our department's experience of the use of Sugammadex for the reversal of neuromuscular blockade. We sought to gain an idea of common specific indications for its use, following pressure to justify the rising drug budget for this relatively new agent. Anaesthetists were asked to fill in an audit form every time Sugammadex was used. Materials and Methods: The reason for using the drug, which NDMR, time from last dose, TOF count, whether the patient was extubated, age, discharge destination, co-morbidities, operation, and other comments were all recorded. We also asked if Sugammadex was used to reverse blockade, did the drug prevent an ITU admission. The audit form was kept next to the Sugammadex in theatre recovery's drug cupboard. Results and Discussion: 72 audit forms were completed (6 patients had no form or missing data) over a one year period. While many patients had multiple co-morbidities, obesity (30), IHD (27), Age>75 (20), Tachycardia (20) and COPD (19) were the most common. 47 patients were admitted to the ward, 21 to HDU, 2 to labour ward and interestingly, only 2 in a year were admitted to ITU. Added comments (though subjective) showed that at least 7 ITU admissions were prevented, and about the same number of HDU admissions. Only one patient received Sugammadex following an RSI, though he was extubated successfully 20 minutes later. All patients got rocuronium as the NDMR. No patients were given Sugammadex in a “Can't Intubate, Can't Ventilate” situation. Conclusion(s): While Sugammadex has been available in Scotland for over 3 years, at present the SMC only recommends its use in the reversal of profound blockade following RSI using rocuronium1. The use to facilitate extubation in the context of serious co-morbidities has been studied and its ability to reverse profound blockade has also been shown2,3. We conclude that our use has been appropriate and has reduced costs by preventing ITU and HDU admissions. AD - D. Alcorn, Royal Alexandra Hospital, Dept of Anaesthesiology and Intensive Care, Glasgow, United Kingdom AU - Bramma, Y. L. AU - Alcorn, D. DB - Embase KW - sugammadex rocuronium clinical audit human anesthesiology patient morbidity ward neuromuscular blocking tachycardia obesity anesthesist budget hospital patient hospital United Kingdom extubation LA - English M3 - Conference Abstract N1 - L71315518 2014-02-17 PY - 2013 SN - 0265-0215 SP - 26 ST - Sugammadex: A one-year prospective audit of its use T2 - European Journal of Anaesthesiology TI - Sugammadex: A one-year prospective audit of its use UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71315518&from=export VL - 30 ID - 482 ER - TY - JOUR AB - Retained surgical material needs to be a possible differential diagnosis for patients presenting with unspecific abdominal pain after especially cavitary emergency surgery. Even though international standard checklists concerning sponge handling and counting exist, RSM could never be ruled out completely. AD - Departement of Visceral-, Thoracic- and Vascular Surgery University Hospital Dresden Dresden Germany. Departement of General Surgery Cantonal Hospital Lucerne Luzern Switzerland. AN - 30997079 AU - Oehme, F. AU - Rühle, A. AU - Stickel, M. AU - Metzger, J. AU - Gass, J. M. C2 - PMC6452485 DA - Apr DO - 10.1002/ccr3.2074 DP - NLM ET - 2019/04/19 IS - 4 KW - Gossypiboma remained surgical material small bowel obstruction vaginal hysterectomy commercial associations (eg, consultancies, stock ownership, equity interest, patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article. I agree and confirm this statement as true. LA - eng N1 - 2050-0904 Oehme, Florian Orcid: 0000-0003-4997-8176 Rühle, Annika Stickel, Michael Metzger, Jürg Gass, Jörn-Markus Case Reports Clin Case Rep. 2019 Mar 6;7(4):753-757. doi: 10.1002/ccr3.2074. eCollection 2019 Apr. PY - 2019 SN - 2050-0904 (Print) 2050-0904 SP - 753-757 ST - The sucked surgical sponge: Rare case of Gossypiboma after vaginal hysterectomy T2 - Clin Case Rep TI - The sucked surgical sponge: Rare case of Gossypiboma after vaginal hysterectomy VL - 7 ID - 229 ER - TY - JOUR AB - Background: Succinylcholine administration is associated with hyperkalemia in patients with a variety of medical conditions, including many neuromuscular disorders. Nonetheless, there is a paucity of literature describing hyperkalemia after the administration of succinylcholine to patients with multiple sclerosis. Case Report: This case report describes a 38-year-old woman with multiple sclerosis who developed life-threatening hyperkalemia after the administration of succinylcholine during rapid sequence intubation. Conclusion: This case highlights the potential for iatrogenic hyperkalemia after succinylcholine in patients with neurologic diseases, including multiple sclerosis. AD - Department of Emergency Medicine, Section of Medical Toxicology, University of Southern California, 1200 North State Street, Los Angeles, CA 90033, United States Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, United States AU - Levine, M. AU - Brown, D. F. M. DB - Scopus DO - 10.1016/j.jemermed.2011.06.062 IS - 2 KW - hyperkalemia intubation multiple sclerosis RSI succinylcholine M3 - Article N1 - Cited By :16 Export Date: 10 November 2020 PY - 2012 SP - 279-282 ST - Succinylcholine-induced hyperkalemia in a patient with multiple sclerosis T2 - Journal of Emergency Medicine TI - Succinylcholine-induced hyperkalemia in a patient with multiple sclerosis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84864964776&doi=10.1016%2fj.jemermed.2011.06.062&partnerID=40&md5=41c3b280fdce2ea8c10224f8457373ad VL - 43 ID - 1364 ER - TY - JOUR AB - The causes of gastrojejunal fistula are unclear. The ingestion of foreign bodies should be considered. We report the case of a 46-year-old man who visited the emergency department with a 3-day history of dysuria, left upper abdominal pain, left flank soreness, and high fever. Physical examination revealed tenderness in the left upper abdominal quadrant and left costovertebral angle. Abdominal computed tomography and gastroduodenoscopy were inconclusive for gastrojejunal fistula with regional peritonitis caused by an ingested toothpick. A 7-cm toothpick was successfully removed through single-port laparoscopy. Toothpick ingestion is a medical emergency because it can lead to acute abdomen and gut perforation. Single-port laparoscopy is a minimally invasive strategy for treating this condition. © 2016 AD - Division of Gastrointestinal Surgery, Department of Surgery, Ren-Ai Branch, Taipei City Hospital, Taipei, Taiwan Division of Nephrology, Department of Surgery, Ren-Ai Branch, Taipei City Hospital, Taipei, Taiwan AU - Chen, C. C. AU - Ting, C. T. AU - Hsu, Y. H. AU - Chen, P. C. AU - Lee, M. D. AU - Liu, M. H. DB - Scopus DO - 10.1016/j.fjs.2016.05.003 IS - 5 KW - laparoscopy peritonitis single-port toothpick M3 - Article N1 - Export Date: 10 November 2020 PY - 2016 SP - 190-192 ST - Successful treatment through single-port laparoscopy for a gastrojejunal fistula caused by an accidentally ingested toothpick T2 - Formosan Journal of Surgery TI - Successful treatment through single-port laparoscopy for a gastrojejunal fistula caused by an accidentally ingested toothpick UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84992363481&doi=10.1016%2fj.fjs.2016.05.003&partnerID=40&md5=d421838929785a5249f141ec0073c6f6 VL - 49 ID - 1169 ER - TY - JOUR AB - We report on a patient in whom, 10 months after lung volume reduction surgery, bovine material visibly migrated to the bronchial lumen. In this particular case, bronchoscopic treatment was successful. The patient remained well 12 months after such treatment. The report also suggests that the alternative use of absorbable material will reduce later postoperative complications. © 2004 by The Society of Thoracic Surgeons. AD - Second Department of Surgery, School of Medicine, Fukuoka University, Fukuoka, Japan Second Department of Surgery, School of Medicine, Fukuoka Univ., 45-1, 7 Chome N., Fukuoka, Japan AU - Iwasaki, A. AU - Yoshinaga, Y. AU - Shirakusa, T. DB - Scopus DO - 10.1016/S0003-4975(03)01467-X IS - 6 KW - 11 M3 - Article N1 - Cited By :8 Export Date: 10 November 2020 PY - 2004 SP - 2156-2157 ST - Successful removal of bovine pericardium by bronchoscope after lung volume reduction surgery T2 - Annals of Thoracic Surgery TI - Successful removal of bovine pericardium by bronchoscope after lung volume reduction surgery UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-9344262895&doi=10.1016%2fS0003-4975%2803%2901467-X&partnerID=40&md5=072d926611064865286784dbfe63190d VL - 78 ID - 1619 ER - TY - JOUR AB - Purpose: Gastric bypass (GBP) surgery is becoming an increasingly popular surgery in the management of obesity. Marginal ulcers (MU) are a common immediate/intermediate complication, with reported incidences up to 3-23%. Suture remnants have been seen in ulcer beds in up to 32% of the cases in one study. Mucosal ischemia, foreign body reaction, traction and bezoar like effect of food have been proposed as the mechanisms causing the ulcers. We present the case of a 57-year-old male s/p GBP surgery for obesity 8 months ago, with a 100-pound weight loss coming to the hospital with severe 10/10 epigastric pain with non-bilious, non-bloody vomiting, abdominal distension, and hypoactive bowel sounds. Basic metabolic work-up and blood counts were normal. Abdominal films and CT scan showed multiple air fluid levels. He was kept NPO and was started on IV hydration. EGD was then performed, which showed evidence of a Roux-en-Y gastrojejunostomy. the G-J anastomosis was characterized by congestion, edema, erythema and an impacted suture. This was traversed. the pouch to jejunum limb was characterized by congestion, edema, erythema and ulceration. the duodenumto- jejunum limb was not reached. the impacted sutures were then cut with a hot biopsy forceps. there were multiple ulcerations in the efferent limb over the jejunal folds in a linear pattern consistent with traction injury from the suture. the patient was started on pantoprazole 40 mg twice a day resulting in complete symptom resolution and ulcer healing. Endoscopy is evolving as a novel technique for the management of GBP related complications. Redundant suture is typically regarded as a normal part of the postoperative anatomy. However, they should be considered a potential etiology of chronic pain in symptomatic patients, and removal is shown to be beneficial and helps prevention and healing of the ulcers. Suture cutting can be accomplished with simple hot biopsy forceps or with regular/flexible endoscopic scissors. AD - G. Aswath, SUNY Upstate Medical University, Syracuse, NY, United States AU - Aswath, G. AU - Manocha, D. AU - Rawlins, S. DB - Embase DO - 10.1038/ajg.2013.267 KW - pantoprazole gastric bypass surgery patient human college gastroenterology suture ulcer limb surgery jejunum obesity traction therapy erythema biopsy forceps edema vomiting epigastric pain jejunum ulcer body weight loss injury hospital etiology food gastrojejunostomy bezoar hydration liquid computer assisted tomography anastomosis foreign body reaction blood cell count intestine sound scissors abdominal distension ischemia ulcer healing endoscopy chronic pain prevention healing male bypass surgery LA - English M3 - Conference Abstract N1 - L71221817 2013-11-15 PY - 2013 SN - 0002-9270 SP - S454 ST - Successful endoscopic management of retained suture related complication in a gastric bypass patient T2 - American Journal of Gastroenterology TI - Successful endoscopic management of retained suture related complication in a gastric bypass patient UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71221817&from=export http://dx.doi.org/10.1038/ajg.2013.267 VL - 108 ID - 475 ER - TY - JOUR AB - Introduction Gastrointestinal perforation related to foreign body ingestion is uncommon. Surgical interventions aiming at removal of the offending agent and restoration of bowel continuity are sought when perforations occur. Presentation of case A 68 year old male presented with epigastric abdominal pain and anorexia for 2 days. On examination, he was febrile and had localized epigastric tenderness. Laboratory investigations revealed marked leucocytosis with no other abnormalities. Computed tomography revealed the presence of a foreign body penetrating through the full thickness of the gastric wall with its tip lying adjacent to the pancreatic head. Endoscopic trial to extract the foreign body was successfully carried out. The gastric defect was sealed by applying an endoscopic metallic clip. Discussion Gastric perforations secondary to foreign body ingestion usually follow an elusive clinical course and are rarely diagnosed early in its course. Early diagnosis allows for the utilization of minimally invasive management. Unfortunately, Most reported cases were diagnosed after intra-abdominal processes, such as abscesses, have ensued. Conclusion This case illustrates the importance of early diagnosis of foreign body related gastrointestinal perforations and emphasizes the role of therapeutic endoscopy. © 2015 Published by Elsevier Ltd. on behalf of Surgical Associates Ltd. This is an openaccess article under the CC BY-NC-ND license. AD - Department of General Surgery, McGill University Health Centre, Montreal, Canada Department of General Surgery, Hôpital du Suroîtl, Salaberry-de-Valleyfield, Canada Department of General Surgery, Barrie Memorial Hospital, Ormstown, Canada AU - Shaheen, M. F. AU - Barrette, P. DB - Scopus DO - 10.1016/j.ijscr.2015.02.012 KW - Endoscopy Foreign body Gastric perforation Minimally invasive M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2015 SP - 12-14 ST - Successful endoscopic management of gastric perforation caused by ingesting a sharp chicken bone T2 - International Journal of Surgery Case Reports TI - Successful endoscopic management of gastric perforation caused by ingesting a sharp chicken bone UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84923118292&doi=10.1016%2fj.ijscr.2015.02.012&partnerID=40&md5=2cbd030bf4b7b0094952d7ca5c3368d0 VL - 9 ID - 1240 ER - TY - JOUR AB - A study was carried out in order to obtain further information about the soft tissue response to thin Apaceram® discs of dense hydroxyapatite (HA) implanted in rats for various periods of time between one day and 10 months. The Apaceram® discs were implanted subcutaneously into the interscapular region of 33 rats. A sham operation was performed on eight rats used as controls. Decalcified histological sections stained with haematoxylin and eosin and Mallory's azan were examined and the different cell types found around the implants were counted. It was found that an acute inflammatory reaction occurred after one day and disappeared at about two weeks after implantation. In the test groups, macrophages and lymphocytes disappeared about one week later, and no inflammatory reaction was observed from one to three months. However, a tissue reaction occurred at six months with the appearance of macrophages and lymphocytes, and decreased gradually at 10 months. Meanwhile, a few foreign body giant cells at the Apaceram®-tissue interface and a thick layer of fibrous connective tissue around the Apaceram® disc were observed at 10 months. No osteogenesis was observed in any specimen. The results obtained so far suggest that Apaceram® is still a useful material for reconstructive surgery, despite the possible appearance of a slight macrophage reaction at six months. © 1995, JLO (1984) Limited. All rights reserved. AD - School of Dentistry, Division of Clinical Otology, 1st Department of Pathology, School of Medicine, Department of Orthodontics, University of Tokushima, Tokushima, 770, Japan AU - Cui, P. C. AU - Ohsaki, K. AU - Ii, K. AU - Tenshin, S. AU - Kawata, T. DB - Scopus DO - 10.1017/S0022215100129135 IS - 1 KW - Biocompatible materials Cell count Histology Hydroxyapatites Rats M3 - Article N1 - Cited By :9 Export Date: 10 November 2020 PY - 1995 SP - 14-18 ST - Subcutaneous tissue reaction to synthetic auditory ossicle (Apaceram®) in rats T2 - The Journal of Laryngology & Otology TI - Subcutaneous tissue reaction to synthetic auditory ossicle (Apaceram®) in rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028955736&doi=10.1017%2fS0022215100129135&partnerID=40&md5=01ab82855c0f1ee308ef62658d780751 VL - 109 ID - 1725 ER - TY - JOUR AB - The discs of synthetic auditory ossicle (Bioceram®), which are composed of aluminium oxide (Al2O3), were implanted subcutaneously in the interscapular region of 16 rats. The implanted specimens were removed at 1, 3, 7 and 14 days after implantation. The decalcified 6 μm thick sections were stained with H.E. and cell types around the implants were counted microscopically. We found that an acute inflammatory reaction occurred at one day, in which macrophages and neutrophiles predominated, and almost disappeared at about 7 days after implantation. Fibrosis began to be observed at 3 days. During this early stage, foreign body giant cells were found in only one specimen at 3 days. These findings, in comparison with those in the controls, showed that the chemical irritation of Bioceram® to the subcutaneous tissue is slight, although the physical and/or chemical irritation of Bioceram® lasts continuously and induces fibrosis around the bioimplant. The results so far suggest that Bioceram® seems to be a satisfactorily biocompatible material, at least within the extent of 2 weeks. AD - First Department of Pathology, University Hospital, University of Tokushima School of Medicine, Tokushima, Japan Division of Clinical Otology, University Hospital, University of Tokushima School of Medicine, Tokushima, Japan Department of Orthodontics, University of Tokushima, School of Dentistry, Tokushima, Japan Department of Orthodontics, Okayama University Dental School, Okayama, Japan Division of Clinical Otology, University Hospital, University of Tokushima School of Medicine, Kuramoto-cho, Tokushima 770-8503, Japan AU - Ye, Q. AU - Ohsaki, K. AU - Ii, K. AU - Li, D. J. AU - Matsuoka, H. AU - Tenshin, S. AU - Yamamoto, T. DB - Scopus IS - 3-4 KW - Aluminum oxide ceramics Biocompatible materials Cell count Histology Rats M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 1998 SP - 173-177 ST - A subcutaneous tissue reaction in the early stage to a synthetic auditory ossicle (Bioceram®) in rats T2 - Journal of Medical Investigation TI - A subcutaneous tissue reaction in the early stage to a synthetic auditory ossicle (Bioceram®) in rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031995778&partnerID=40&md5=8f3200def9e45fac9be8591cad366d0c VL - 44 ID - 1698 ER - TY - JOUR AB - Cellular response and inflammatory reaction to synthetic auditory ossicle (Bioceram®) made from aluminium oxide are investigated. Local inflammatory effects are important in wound healing and in determining biocompatibility of an implant, necessitating the study of biologic effects of implants, especially inflammation and fibrous capsule formation. Bioceram® discs were implanted subcutaneously in the interscapular region of rats for various periods of time, ranging from 1 day to 300 days. Histological sections 6 μm thick were stained with haematoxylin and eosin. Cell types around the implants were examined quantitatively by light microscopy. Inflammatory cell reaction to Bioceram® decreased rapidly within 14 days, similar to the reaction in control groups. From 30 days to 300 days after implantation, there was continuous reduction to very low levels for macrophages and lymphocytes, but fibrous connective tissue capsule around implants matured. Preliminary results suggest that Bioceram® is a satisfactory biocompatible material for reconstructive surgery from the viewpoint of cellular response. We also briefly discuss the different tissue responses in light of our previous study on hydroxyapatite (Apaceram®). AD - 1st Department of Pathology, University Hospital, University of Tokushima, Tokushima, Japan Division of Clinical Otology, University Hospital, University of Tokushima, Tokushima, Japan Department of Orthodontics, University of Tokushima, School of Dentistry, Tokushima, Japan Department of Orthodontics, Okayama University Dental School, Okayama, Japan Division of Clinical Otology, University Hospital, Univ. of Tokushima, Sch. of Medicine, Tokushima 770-8503, Japan AU - Ye, Q. AU - Ohsaki, K. AU - Ii, K. AU - Li, D. J. AU - Zhu, C. S. AU - Yamashita, Y. AU - Tenshin, S. AU - Takano-Yamamoto, T. DB - Scopus DO - 10.1080/00016489950181990 IS - 1 KW - Aluminium oxide Biocompatibility Cell count Ceramics Histology M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 1999 SP - 83-88 ST - Subcutaneous inflammatory reaction to a synthetic auditory ossicle (Bioceram®) in rats T2 - Acta Oto-Laryngologica TI - Subcutaneous inflammatory reaction to a synthetic auditory ossicle (Bioceram®) in rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033050853&doi=10.1080%2f00016489950181990&partnerID=40&md5=0b01787f3b70999dc1818a3ab19ecfc9 VL - 119 ID - 1689 ER - TY - JOUR AB - The postoperatively retained foreign body (PORFB) can induce complications leading to the need for follow-up surgery to ensure its removal, to treat or prevent the formation of an abscess, and to minimize the risk of death for the patient and liability for the surgeon and hospital. The most common cause of PORFB complications is the surgical sponge. Previously, PORFB prevention was focused on improved efficiency in RFB counting; however, because of the inability to entirely eliminate human error, cost, and the potentially unproven patient outcome improvement, new approaches have been sought. We examined the use of a novel bioengineered, biodegradable sponge (BSS) to reduce the risk of complications due to PORFBs, thus potentially improving patient outcomes. AD - Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA. basiyan@hotmail.com AN - 23079944 AU - Asiyanbola, B. DO - 10.3233/thc-2012-00700 DP - NLM ET - 2012/10/20 IS - 5 KW - Animals Biomedical Engineering/economics/*methods Cost-Benefit Analysis Disease Models, Animal Foreign Bodies/complications/economics/*prevention & control Humans Postoperative Complications/economics/etiology/*prevention & control Surgical Sponges/*adverse effects/economics Swine Time Factors LA - eng N1 - 1878-7401 Asiyanbola, Bola Journal Article Netherlands Technol Health Care. 2012;20(5):387-93. doi: 10.3233/THC-2012-00700. PY - 2012 SN - 0928-7329 SP - 387-93 ST - A study of the bioengineered surgical sponge T2 - Technol Health Care TI - A study of the bioengineered surgical sponge VL - 20 ID - 130 ER - TY - JOUR AB - Background: Implantation of intraocular contact lens(ICL) in crystal eyes is a kind of new operation which can correct high myopia. As a kind of new material, collagen has been applied abroad to research and manufacture of ICL, while there is no similar domestic products. Objective: To observe the cellular response after implantation of collagen ICL in rabbit eyes and evaluate biocompatibility of collagen by animal experiments. Design: A randomized and control grouping experiment was designed. Setting and participants: The exporment was carried out in Department of Ophthalmology in the Affiliated Xinhua Hospital of Shanghai second Medical University. Twenty adult New Zealand white rabbits weighing from 2.0 kg to 2.5 kg, were selected without distinction of sex. Intervention: These experimental rabbits were randomly divided into three groups including 1 ICL implantation group; 2 surgical control group; 3 blank control group. On the 14th and 28th days after surgery, the experimental rabbits were killed and their eyeballs were extracted. Then the anterior segment tissue and ICL were taken out. HE stain, light microscopy, transmission and scanning electron microscope were used to observe and photograph. Main outcome measure: The morphological changes of histocytes on the surface of ICL and ocular anterror tissue were observed. Results: In ICL implantation group, the infiltration of plenty of phagocytes was major in ocular anterior segment tissues in the earlier period after operation, and the phagocytes were functionally active. There were only a few fibroblasts. The number of macrophages decreased in the later period, while the number of fibroblasts increased. In surgical control group many macrophages existed in ocular anterior tissue in the earlier period after operation and the number of fibroblasts increased significantly accompanied with fibrous tissue formation in the later period. Conclusion: Changes of inflammatory cells after ICL implantation showed a progress of classic foreign-body granulomatous inflammation. There was excellent ocular biocompatibility in collagen ICL. AD - Department of Ophthalmology, Xinhua Hospital, Shanghai Second Medical University, Shanghai 200092, China AU - Gu, Z. S. AU - Sheng, Y. H. AU - Zhu, Z. R. AU - Gao, J. B. DB - Scopus IS - 8 M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2004 SP - 1596-1598 ST - Study of biocompatibility on implantation of collagen intraocular contact lens in rabbit eyes T2 - Chinese Journal of Clinical Rehabilitation TI - Study of biocompatibility on implantation of collagen intraocular contact lens in rabbit eyes UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-2442545183&partnerID=40&md5=9fd82edd832ce8f297676c1ad89e952b VL - 8 ID - 1631 ER - TY - JOUR DB - Medline IS - 3 KW - article foreign body health services research human medical error methodology operating room perioperative period safety standard surgical equipment system analysis United States LA - English M3 - Article N1 - L351673145 2008-05-21 PY - 2008 SN - 8756-8047 SP - 5, 7 ST - Study examines counts, retained items T2 - OR manager TI - Study examines counts, retained items UR - https://www.embase.com/search/results?subaction=viewrecord&id=L351673145&from=export VL - 24 ID - 603 ER - TY - JOUR AB - Introduction: Bezoars are foreign-bodies classified by their composition, with phytobezoars (indigested vegetable matter) being the most common. They are a rare entity usually found incidentally on imaging or routine endoscopy and tend to occur in patients with altered gastric anatomy such as following surgery. To our knowledge, no case reports exist of a small-intestinal phytobezoar following an unreversed pyloric-exlusion gastrojejunstomy. Case: A 19 year-old female with a history of blunt abdominal trauma at 18-months requiring pyloric-exclusion gastrojejunostomy presented with right-upper-quadrant (RUQ) abdominal pain, nausea, vomiting, and diarrhea associated with a 20-lb weight loss over the past few months. Her vital signs, complete blood count, and basic metabolic profile were unremarkable. Abdominal computed tomography with intravenous contrast revealed a large, ovoid, low-attenuation mass within the RUQ measuring 6.6 cm x 5.3 cm x 6.9 cm. Magnetic resonance imaging confirmed a mass in the duodenal bulb, most consistent with a bezoar (Panel A). Subsequent upper endoscopy exposed the yellow-colored bezoar extending from the 3rd portion of the duodenum into the proximal jejunum (Panel B). Additionally, it was noted on endoscopy that the patient's pyloric-exclusion was never reversed, suggesting the bezoar likely formed due to years of reflux from the jejunum into the duodenum. A schematic diagram of the location of the bezoar is provided (Panel C). Due to technical difficulty reaching the bezoar and insufficient pyloric dilatation endoscopically, she ultimately required surgical intervention with pyloroplasty to achieve complete removal of the bezoar. At follow-up, she reported resolution of symptoms and improvement in appetite with weight gain and regular bowel function. Discussion: Pyloric-exclusion gastrojejunostomy is performed as a temporizing measure when duodenal ischemia is suspected, as in our patient following blunt abdominal trauma. However, in unusual cases where patients do not have the pyloric exclusion reversed, reflux of food material into the duodenum can occur and result in a symptomatic bezoar formation. (Figure Presented). AD - K. Kukreja, University of Texas, Health Science Center at Houston, Houston, TX, United States AU - Kukreja, K. AU - Meriwether, M. AU - Maiti, A. AU - Faruki, A. AU - Salahudeen, A. AU - Rahimi, E. F. DB - Embase DO - 10.1038/ajg.2017.325 KW - abdominal blunt trauma abdominal pain adult ampulla of Vater appetite attenuation bezoar blood cell count body weight gain body weight loss case report clinical article computer assisted tomography conference abstract diarrhea dilatation endoscopy female follow up gastrointestinal tract gastrojejunostomy human intestine function ischemia jejunum nausea and vomiting nuclear magnetic resonance imaging pyloroplasty surgery vital sign young adult LA - English M3 - Conference Abstract N1 - L620841121 2018-03-01 PY - 2017 SN - 1572-0241 SP - S1342-S1343 ST - Stuck in the gut. An unusual duodenal bezoar following pyloric-exclusion gastrojejunostomy T2 - American Journal of Gastroenterology TI - Stuck in the gut. An unusual duodenal bezoar following pyloric-exclusion gastrojejunostomy UR - https://www.embase.com/search/results?subaction=viewrecord&id=L620841121&from=export http://dx.doi.org/10.1038/ajg.2017.325 VL - 112 ID - 365 ER - TY - JOUR AB - PURPOSE: The aim of this study was to report three cases of stromal rejection after deep anterior lamellar keratoplasty using big bubble technique in keratoconus. METHODS: Deep anterior lamellar keratoplasty was performed in 3 cases of keratoconus (11-19 years of age) using the "big bubble" technique. All of them presented 4 to 19 months after uneventful surgeries with variable decrease of vision (1/200-20/200) along with foreign body sensation, mild pain, and corneal edema. Suture infiltrates were present in all eyes. Ultrasound pachymetry showed variable increase in central corneal thickness (711-894 μm). These patients with stromal rejection were administered pulse intravenous methylprednisolone, 500 mg in 150 mL of 5% dextrose and were started on 1% prednisolone acetate eye drops 1 hourly, moxifloxacin hydrochloride 0.5% 4 times a day along with homatropine 2% eye drops 4 times a day. RESULTS: Complete recovery of the stromal rejections was attained with clear graft and recovery of visual acuity (≥20/40) in all eyes. Central corneal thickness returned to prerejection values in all the eyes after 7 days. There was no significant change in specular count. CONCLUSIONS: Deep anterior lamellar keratoplasty does not eliminate the risk of stromal rejection. Suture-related factors in the form of suture infiltrates and loose suture are an important risk factor for graft rejection. Graft rejection if treated promptly is reversible. AD - Department of Ophthalmology, Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India. namrata103@hotmail.com AN - 23392301 AU - Sharma, N. AU - Kandar, A. K. AU - Singh Titiyal, J. DA - Mar DO - 10.1097/ICL.0b013e31824ccb91 DP - NLM ET - 2013/02/09 IS - 2 KW - Adolescent Anti-Bacterial Agents/therapeutic use Anti-Inflammatory Agents/therapeutic use Child *Corneal Stroma Corneal Transplantation/*methods Female Graft Rejection/drug therapy/*etiology Humans Keratoconus/*surgery Male Parasympatholytics/therapeutic use Treatment Outcome Young Adult LA - eng N1 - 1542-233x Sharma, Namrata Kandar, Asim Kumar Singh Titiyal, Jeewan Case Reports Journal Article Review United States Eye Contact Lens. 2013 Mar;39(2):194-8. doi: 10.1097/ICL.0b013e31824ccb91. PY - 2013 SN - 1542-2321 SP - 194-8 ST - Stromal rejection after big bubble deep anterior lamellar keratoplasty: case series and review of literature T2 - Eye Contact Lens TI - Stromal rejection after big bubble deep anterior lamellar keratoplasty: case series and review of literature VL - 39 ID - 134 ER - TY - JOUR AB - A surgery center found that efforts to streamline endocrine surgical trays led to faster tray preparation time and saved $31.62 per operation in reprocessing costs. By streamlining trays for a more exact fit with each procedure, the hospital projected a $28,000 annual savings in instrument reprocessing. AN - 139844176. Language: English. Entry Date: 20191128. Revision Date: 20191128. Publication Type: Article. Journal Subset: Biomedical AU - Ahc, Media DB - ccm DP - EBSCOhost IS - 8 KW - Surgicenters Surgical Count Procedure Surgical Instruments -- Economics Health Care Costs Cost Savings Time Management Equipment Reuse -- Economics Operating Room Personnel Surgeons -- Psychosocial Factors Surgical Instruments -- Utilization Sterilization and Disinfection N1 - Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2019 SN - 0190-5066 SP - N.PAG-N.PAG ST - Streamlined Surgical Trays Can Lead to Time, Money Savings T2 - Same-Day Surgery TI - Streamlined Surgical Trays Can Lead to Time, Money Savings UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=139844176&site=ehost-live&scope=site VL - 43 ID - 719 ER - TY - JOUR AB - Cardiopulmonary bypass (CPB) precipitates inflammation that causes marked pulmonary dysfunction. Leukocyte filtration has been proposed to reduce these deleterious effects. Other studies show an improvement with aprotinin. We proposed that a combination of these two therapies would synergistically improve pulmonary outcomes. Two hundred and twenty-five patients participated in a randomized prospective study comparing pulmonary microvascular function and pulmonary shunt fraction postcoronary artery bypass grafting (CABG). The study group underwent leukocyte depletion with aprotinin during the procedure. Pulmonary microvascular function was assessed by pulmonary microvascular pressure (PMVP), a measure of pulmonary capillary edema, and pulmonary function was evaluated by comparing pulmonary shunt fractions. Elevated PMVP and increased pulmonary shunting compromise pulmonary performance. The leukocyte-depleted group had significantly reduced PMVP and pulmonary shunt fraction for at least the first 24 hours postbypass. The combination of strategic leukocyte filtration and aprotinin therapy can effectively reduce postoperative decline in pulmonary function. Cardiopulmonary bypass precipitates a variety of inflammatory effects that can cause marked pulmonary dysfunction to the point of respiratory failure, necessitating prolonged mechanical ventilation. Leukocyte filtration has been investigated previously and appears to be beneficial in improving pulmonary outcome by preventing direct neutrophil-induced inflammatory injury. Recent studies of leukocyte reduction profiles suggest that leukoreduction via leukofiltration is short lived with filter saturation occurring 30-45 minutes after onset of filtration. This phenomenon may explain the limited utility observed with higher risk patients. These patients typically require longer pump runs, so leukocyte reduction capability is suboptimal at the time of pulmonary vascular reperfusion. To more effectively protect the lung from reperfusion injury, leukocyte filtration can be delayed so that reduction of activated neutrophils is maximal at the time of pulmonary vascular reperfusion. It is, thus, conceivable that a timely use of arterial line leukoreducing filters may improve, more substantially, pulmonary function postbypass. Two hundred and twenty-five isolated coronary revascularization patients participated in this prospective, randomized trial. The patients received moderately hypothermic CBP alone (control group: n = 110) or combined with leukocyte depletion, initiated 30 minutes before crossclamp release, with filters placed in the bypass circuit (study group: n = 115). All patients also received full Hammersmith aprotinin dosing during the operation. Pulmonary microvascular pressures were lower in the study group at three hours postbypass, and continued to fall until 24 hours postbypass. In contrast, the control group measured a rise in PMVP and a continued plateau throughout 24 hours postbypass (p < 0.028). The calculated pulmonary shunt fraction also was reduced significantly throughout the study interval, with the greatest reduction occurring approximately three to six hours post-CPB (p < 0.002). Shunt fractions eventually converged at 24 hours postbypass. Outcome measures included hospital charges and length of stay, which were also markedly reduced in the treatment group. Increasing PMVPs are a direct reflection of pulmonary capillary edema, which, in conjunction with increased pulmonary shunt ratio, lead to an overall worsening of pulmonary function. Intraoperative strategic leukocyte filtration combined with aprotinin treatment improves post-CPB lung performance by reducing significantly the reperfusion inflammatory response and its sequelae. These benefits are manifested by reductions in ventilator times, hospital stay and patient morbidity. AD - Department of Surgery, Cardiovascular Research Institute, Univ. North Texas Hlth. Sci. Center, Forth Worth, TX 76107, United States AU - Olivencia-Yurvati, A. H. AU - Ferrara, C. A. AU - Tierney, N. AU - Wallace, N. AU - Mallet, R. T. DB - Scopus DO - 10.1191/0267659103pf625oa IS - SUPPL. 1 M3 - Article N1 - Cited By :36 Export Date: 10 November 2020 PY - 2003 SP - 23-31 ST - Strategic leukocyte depletion reduces pulmonary microvascular pressure and improves pulmonary status post-cardiopulmonary bypass T2 - Perfusion TI - Strategic leukocyte depletion reduces pulmonary microvascular pressure and improves pulmonary status post-cardiopulmonary bypass UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037272342&doi=10.1191%2f0267659103pf625oa&partnerID=40&md5=88b0549314500c18e5d59dd50827d2d0 VL - 18 ID - 1643 ER - TY - JOUR AB - When blood monocytes from sheep are grown upon glass in 100% autologous plasma they divide with low mitotic indices, but if the plasma is taken from the sheep three or four days after the implantation of a small Teflon or stainless steel cylinder, the maximum mitotic indices of the monocytes cultured in that plasma rise. Plasma collected from the sheep in the first two days after operation is often toxic to cultured autologous monocytes. An equivalent sham operation increases the mitogenicity of the plasma, but without a preceding toxic period. No consistent effects upon the numbers of circulating blood monocytes were noted following implantation operations. A hypothesis is presented which suggests that blood monocyte multiplication in vivo and in vitro is dependent upon (a) a lesion which causes cell attachment, and (b) a humoral component of the plasma which stimulates mitosis. Surgery, and the implantation of foreign materials will increase the concentration of such a substance in plasma. © 1977 The Physiological Society AD - A.R.C. Institute of Animal Physiology, Babraham, Cambridge, CB2 4AT, United Kingdom AU - Greenwood, B. DB - Scopus DO - 10.1113/expphysiol.1977.sp002381 IS - 2 M3 - Article N1 - Export Date: 10 November 2020 PY - 1977 SP - 107-119 ST - THE STIMULATION OF SHEEP MONOCYTE MITOSIS IN VITRO BY AUTOLOGOUS PLASMA TAKEN AFTER SURGERY AND THE IMPLANTATION OF FOREIGN MATERIAL T2 - Quarterly Journal of Experimental Physiology and Cognate Medical Sciences TI - THE STIMULATION OF SHEEP MONOCYTE MITOSIS IN VITRO BY AUTOLOGOUS PLASMA TAKEN AFTER SURGERY AND THE IMPLANTATION OF FOREIGN MATERIAL UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0017354721&doi=10.1113%2fexpphysiol.1977.sp002381&partnerID=40&md5=29519b2847333afc746a6f15443ecc6f VL - 62 ID - 1768 ER - TY - JOUR AB - We report a case of silicone-induced Still's-like inflammatory syndrome diagnosed after extensive investigation in the department of internal medicine of a secondary hospital. A 45-year-old female healthcare specialist presented with fever, headache, sore throat, myalgia and fatigue. A history of breast augmentation surgery in 2007 was confirmed. Physical examination of the patient was normal while laboratory tests showed a very high white blood cell count. The patient was admitted to hospital due to suspected infection and further laboratory tests were carried out. Inflammatory markers were persistently high despite empirical treatment with doxycycline for possible infection by Rickettsia/Coxiella. As the fever did not resolve and the patient had not improved after more than 3 weeks, the case was investigated as fever of unknown origin. Eventually, the existence of liver granulomas as well as the presence of anti-silicone antibodies confirmed the diagnosis of silicone-induced Still's-like inflammatory syndrome. In conclusion, this case supports a linkage between silicone breast implants and autoimmune connective tissue diseases. LEARNING POINTS: Consider and investigate a silicone-induced foreign body reaction as a cause of fever of unknown origin.Consider the possible harmful outcomes of breast augmentation.Develop a greater understanding of the potential linkage between silicone breast implants and autoimmune connective tissue diseases. AD - Department of Internal Medicine, Nicosia University General Hospital, Nicosia, Cyprus. AN - 30755905 AU - Lavranos, G. AU - Kouma, D. AU - Deveros, A. AU - Pigiotou, G. AU - Samanis, G. AU - Zintilis, C. C2 - PMC6346920 DO - 10.12890/2016_000513 DP - NLM ET - 2017/01/27 IS - 1 KW - Breast implants Still’s disease fever of unknown origin silicone LA - eng N1 - 2284-2594 Lavranos, Giagkos Kouma, Demetra Deveros, Antonis Pigiotou, Georgia Samanis, Georgios Zintilis, Chrysostomos Journal Article Eur J Case Rep Intern Med. 2017 Jan 27;4(1):000513. doi: 10.12890/2016_000513. eCollection 2017. PY - 2017 SN - 2284-2594 SP - 000513 ST - Still's-like Disease Induced by Breast Implants in a Middle-Aged Female Health Professional T2 - Eur J Case Rep Intern Med TI - Still's-like Disease Induced by Breast Implants in a Middle-Aged Female Health Professional VL - 4 ID - 188 ER - TY - JOUR AB - Background. Montgomery salivary bypass tubes (MSBTs) have been used for decades in the treatment of stenoses and fistulae of the hypopharynx and the cervical esophagus. Generally, MSBT use is not associated with serious complications. Only a small number of cases with severe MSBT-associated complications have been reported in the literature. Methods. and Results. We report for the first time an MSBT migration to the ileum in a laryngectomized patient who underwent surgical pharyngocutaneous fistula closure with MSBT placement. The MSBT was removed surgically via laparotomy. The patient died 15 days later due to sepsis associated with peritonitis. Conclusion. To avoid potentially lethal complications associated with MSBT migration into the intestinal tract, we recommend secure fixation of the MSBT to a nasogastric tube. © 2010 Wiley Periodicals, Inc. AD - Department of Otorhinolaryngology, Friedrich-Schiller University, Jena, Germany Department of General, Visceral and Vascular Surgery, Friedrich-Schiller University, Jena, Germany AU - Bitter, T. AU - Pantel, M. AU - Dittmar, Y. AU - Guntinas-Lichius, O. AU - Wittekindt, C. DB - Scopus DO - 10.1002/hed.21489 IS - 1 KW - complication dislocation migration pharyngocutaneous fistula salivary bypass tube M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2012 SP - 135-137 ST - Stent migration to the ileum-A potentially lethal complication after montgomery salivary bypass tube placement for hypopharyngeal stenosis after laryngectomy T2 - Head and Neck TI - Stent migration to the ileum-A potentially lethal complication after montgomery salivary bypass tube placement for hypopharyngeal stenosis after laryngectomy UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-83455201113&doi=10.1002%2fhed.21489&partnerID=40&md5=f8119827cc335137605e9c7eb2ac561d VL - 34 ID - 1392 ER - TY - JOUR AB - Count sheets, when placed in contact with surgical instruments during steam sterilization, can transfer ink to the instruments. To explore whether this poses a safety concern, stainless steel instruments were placed on top of completely inked paper and subjected to steam sterilization, extracted, and tested for cytotoxicity. Preprinted labels were examined in a similar fashion. Extracts from stainless steel devices exposed to ink, toner, or labels showed no significant cytotoxic response, although the ink residue on the devices after steam sterilization is difficult to remove and detrimental to the instrument. Placing a barrier between the count sheet and the devices facilitates reuse of the instruments. AORN J 89 (March 2009) 521-531. (c) AORN, Inc, 2009. AD - Chemist, US Food and Drug Administration Center for Device and Radiological Health OSEL/DB, Silver Spring, MD AN - 105475578. Language: English. Entry Date: 20090522. Revision Date: 20200708. Publication Type: Journal Article AU - Lucas, A. D. AU - Chobin, N. AU - Conner, R. AU - Gordon, E. A. AU - Mitchell, S. AU - Perry, B. AU - Stratmeyer, M. E. DB - ccm DO - 10.1016/j.aorn.2008.09.001 DP - EBSCOhost IS - 3 KW - Sterilization and Disinfection -- Adverse Effects Sterilization and Disinfection -- Methods Surgical Count Procedure -- Equipment and Supplies Surgical Equipment and Supplies Biological Assay Toxicity Tests Human N1 - pictorial; research; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PMID: NLM19269377. PY - 2009 SN - 0001-2092 SP - 521-531 ST - Steam sterilization and internal count sheets: assessing the potential for cytotoxicity T2 - AORN Journal TI - Steam sterilization and internal count sheets: assessing the potential for cytotoxicity UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105475578&site=ehost-live&scope=site VL - 89 ID - 790 ER - TY - JOUR AB - The number of patients with pseudomonas corneal ulcer was 135 out of 397, 380 cases in 21 eye departments during the period from Jan. 1961 to Sept. 1966. The incidence of the disease increased from 1964. The greatest number of patients was found in the age class 21-30 yr and much more in males than females. The rate of incidence was prevalent in August. The infection was caused much more frequently after removal of foreign bodies from the cornea, and almost all of them were caused by iron filings during grinding. Pseudomonas aeruginosa isolated from patients was most sensitive to polymyxin-B, colistin, and then SM, TC and FM. The disease was treated by colistin and CP. These were used frequently locally as well as systemically. SM, TC, KM and FM were employed too. Better visuel acuities (more than 0.5) were obtained frequently in cases treated within 3 days alter the onset of the infection, while poor visual acuities (less than finger counting) were attained in cases treated within more than 7 days and almost all were subjected to enucleation. Therefore, it. seems to be most important to treat as promptly as possible and with the most effective antibiotics. AD - M. Mikuni, Dept. of Ophthalmol., Med. Sch., Niigata Univ., Niigata, Japan AU - Mikuni, M. AU - Oiehi, M. AU - Suda, S. AU - Imai, M. AU - Takahashi, T. DB - Embase Classic IS - 8 KW - antibiotic agent colistin iron polymyxin B cornea cornea ulcer documentation enucleation eye female foreign body grinding infection male patient Pseudomonas Pseudomonas aeruginosa visual acuity LA - English M3 - Article N1 - L288052918 1967-12-01 PY - 1967 SP - 1217-1224 ST - Statistic observation on pseudomonas corneal ulcer T2 - Acta Soc.Ophthal. Jap. TI - Statistic observation on pseudomonas corneal ulcer UR - https://www.embase.com/search/results?subaction=viewrecord&id=L288052918&from=export VL - 71 ID - 693 ER - TY - JOUR AB - Two cases of starch granulomatous peritonitis, one symptomatic and one asymptomatic, are presented. Although starch glove powder is usually innocuous, the number of cases of starch peritonitis reported in the literature indicates that it is not always so. The typical syndrome consists of abdominal pain, fever, and signs of peritonitis. The leukocyte count is usually within the normal range, but sometimes eosinophilia is present. Signs and symptoms characteristically develop 10 to 40 days after an uneventful operation. The diagnosis can be confirmed by finding starch granules in the tissue and in foreign body giant cells. Reoperation may be avoided by suspecting the syndrome and searching for starch in ascitic fluid obtained by paracentesis. Therapy consists of steroids or an antiinflammatory agent such as indomethacin. AD - Dept. Gynecol., Univ. Texas System Cancer Cent., M.D. Anderson Hosp., Houston, Tex. AU - Ehrlich, C. E. AU - Wharton, J. T. AU - Gallager, H. S. DB - Embase Medline IS - 4 KW - glove powder indometacin starch unclassified drug article ascites clinical study drug induced disease drug therapy eosinophilia giant cell granuloma granulomatous peritonitis histology major clinical study microscopy oral drug administration paracentesis peritonitis starch granuloma therapy LA - English M3 - Article N1 - L5000784 1975-01-01 PY - 1974 SN - 0038-4348 SP - 443-446 ST - Starch granulomatous peritonitis T2 - Southern Medical Journal TI - Starch granulomatous peritonitis UR - https://www.embase.com/search/results?subaction=viewrecord&id=L5000784&from=export VL - 67 ID - 688 ER - TY - JOUR AB - LEARNING OBJECTIVE 1: Demonstrate the pathogenicity of coagulase-negative staphylococcus. LEARNING OBJECTIVE 2: Review the clinical presentation of infective endocarditis. CASE: A 49-year-old woman with HIV (CD4 count 101 cells/uL) and end stage renal disease presented with 9 days of progressive shortness of breath after a revision of her arteriovenous (AV) fistula for dialysis. She also noted generalized fatigue, subjective fever, four-pillow orthopnea and new-onset paroxysmal nocturnal dyspnea. Her temperature was 99.2 ° F, blood pressure 132/74, respirations 16, and saturation 99% on room air. She had a 3/6 systolic ejection murmur noted at previous admissions as well as a new regurgitant murmur loudest in the mitral position, jugular venous distention, and 1+ lower extremity pitting edema. There was no erythema surrounding her right upper extremity AV fistula. WBC count was 14.2×10e3/uL with left shift. On day 2, she developed a fever to 101.6 ° F. Blood cultures from two sites grew coagulase-negative staphylococcus and repeat cultures were drawn. Blood cultures remained persistently positive for Staphylococcus lugdunensis for 8 days. A transthoracic echocardiogram (TTE) with bubble study showed an ejection fraction of 55-60 %, no shunt, and a vegetation on the atrial aspect of the anterior mitral leaflet. She was treated with nafcillin while inpatient and then transitioned to 6 weeks of cefazolin with dialysis. DISCUSSION: Internists commonly encounter heart murmurs, and their etiology can be either benign or pathogenic. A high degree of suspicion for infective endocarditis (IE) with a new or changed heart murmur is imperative because endocarditis can rapidly cause irreversible damage to the heart. IE in chronic hemodialysis patients is significantly more common and causes greater morbidity and mortality than in the general population, being second only to cardiovascular disease as the leading cause of death in this group. Staphylococcus lugdunensis is a coagulase-negative staphylococcus (CONS) that like other CONS infections can range from a harmless skin flora to a life-threatening pathogen. S. lugdunensis affects native valves with greater frequency than prosthetic valves, unlike other CONS. IE due to this organism is characterized by a high mortality and rapid tissue destruction. Often, hospital laboratories will report non-aureus isolates only as CONS, but speciation of the organism can assume great importance in defining therapeutic approach. For example, the clinical outcome in the treatment of S. lugdunensis is much more favorable with valvular replacement than with antibiotics alone. Despite their frequency as contaminants, CONS have become important nosocomial pathogens, accounting for 9 % of all nosocomial infections. CONS are also the third most common cause of blood stream infections. The incidence of CONS bacteremia in patients with foreign bodies such as a port is increased compared to the general population due to their strong adherence to polymer surfaces and biofilm formation. It is important to assess the clinical picture when faced with CONS-positive blood cultures because these organisms are not always contaminants, and can cause significant morbidity and mortality when not treated appropriately. AD - J.M. Collins, Tulane University Health Sciences Center, New Orleans, LA, United States AU - Collins, J. M. AU - Miller, C. S. DB - Embase KW - CD4 antigen cefazolin nafcillin antibiotic agent polymer Staphylococcus lugdunensis society internal medicine human blood culture mortality coagulase negative Staphylococcus organisms bacterial endocarditis population pathogenesis morbidity heart murmur fever dialysis arteriovenous fistula blood pressure heart temperature etiology paroxysmal dyspnea fatigue vegetation female pathogenicity hospital patient heart ejection fraction patient biofilm bacteremia internist bloodstream infection echocardiography endocarditis hemodialysis hemodialysis patient hospital infection tissues heart valve prosthesis leukocyte count dyspnea arm erythema skin flora edema end stage renal disease hospital laboratory infection cause of death leg cardiovascular disease systolic heart murmur ambient air foreign body Human immunodeficiency virus LA - English M3 - Conference Abstract N1 - L71495777 2014-06-17 PY - 2014 SN - 0884-8734 SP - S437-S438 ST - Staphylococcus lugdunensis: The great cons artist T2 - Journal of General Internal Medicine TI - Staphylococcus lugdunensis: The great cons artist UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71495777&from=export VL - 29 ID - 452 ER - TY - JOUR AB - METHODS: Based on a nationwide registration, the clinical and bacteriologic data from 61 postoperative and 43 hematogenous cases of Staphylococcus aureus meningitis in Denmark from 1986 through 1989 were reviewed. RESULTS: Postoperative meningitis was a foreign body infection in 89% of the cases and had a lower mortality (18% [11/61]) compared with hematogenous meningitis (56% [24/43]). Hematogenous S aureus meningitis seems to be part of an overwhelming, disseminated infection as indicated by the following: 81% of the patients had bacteremia, 21% had endocarditis, and 12% had osteomyelitis. Most patients were older, often with underlying diseases, community-acquired infections, and a clinical picture of severe meningitis. The major findings were mental status changes and a high rate (34%) of focal neurological changes. The initial leukocyte count in the cerebrospinal fluid sample was low, and the bacteria were seen in Gram's stain smears in 40% of cases only. The prognosis was related to the age of the patients and the initial antibiotic treatment. Patients treated with penicillinase-stable penicillins in combination with fusidic acid may have a better prognosis. Three (12%) of 25 surviving patients had severe sequelae. CONCLUSIONS: Hematogenous S aureus meningitis is a severe disease with a high mortality related to age, presence of shock, and infection with strains of phage type 95. AD - Department of Clinical Microbiology, Bispebjerg Hospital, Copenhagen, Denmark. AN - 8250650 AU - Jensen, A. G. AU - Espersen, F. AU - Skinhøj, P. AU - Rosdahl, V. T. AU - Frimodt-Møller, N. DA - Aug 23 DO - 10.1001/archinte.153.16.1902 DP - NLM ET - 1993/08/23 IS - 16 KW - Adolescent Adult Aged Aged, 80 and over Bacteremia/complications Child Child, Preschool Female Humans Infant Infant, Newborn Male Meningitis, Bacterial/diagnosis/drug therapy/*etiology Middle Aged Penicillin Resistance Postoperative Complications/microbiology Staphylococcal Infections/diagnosis/drug therapy/*etiology Staphylococcus aureus Treatment Outcome LA - eng N1 - Jensen, A G Espersen, F Skinhøj, P Rosdahl, V T Frimodt-Møller, N Journal Article Review United States Arch Intern Med. 1993 Aug 23;153(16):1902-8. doi: 10.1001/archinte.153.16.1902. PY - 1993 SN - 0003-9926 (Print) 0003-9926 SP - 1902-8 ST - Staphylococcus aureus meningitis. A review of 104 nationwide, consecutive cases T2 - Arch Intern Med TI - Staphylococcus aureus meningitis. A review of 104 nationwide, consecutive cases VL - 153 ID - 20 ER - TY - JOUR AB - Differences in physico-chemical characteristics of bone grafts to fill bone defects have been demonstrated to influence in vitro bacterial biofilm formation. Aim of the study was to investigate in vivo staphylococcal biofilm formation on different calcium phosphate bone substitutes. A foreign-body guinea-pig infection model was used. Teflon cages prefilled with β-tricalcium phosphate, calcium-deficient hydroxyapatite, or dicalcium phosphate (DCP) scaffold were implanted subcutaneously. Scaffolds were infected with 2 × 103 colony-forming unit of Staphylococcus aureus (two strains) or S. epidermidis and explanted after 3, 24 or 72 h of biofilm formation. Quantitative and qualitative biofilm analysis was performed by sonication followed by viable counts, and microcalorimetry, respectively. Independently of the material, S. aureus formed increasing amounts of biofilm on the surface of all scaffolds over time as determined by both methods. For S. epidermidis, the biofilm amount decreased over time, and no biofilm was detected by microcalorimetry on the DCP scaffolds after 72 h of infection. However, when using a higher S. epidermidis inoculum, increasing amounts of biofilm were formed on all scaffolds as determined by microcalorimetry. No significant variation in staphylococcal in vivo biofilm formation was observed between the different materials tested. This study highlights the importance of in vivo studies, in addition to in vitro studies, when investigating biofilm formation of bone grafts. © 2015, The Author(s). AD - Infectious Diseases Service, Department of Internal Medicine, University Hospital Lausanne (CHUV), Lausanne, Switzerland Unit of Septic Surgery, Department of Surgery and Anaesthesiology, University Hospital Lausanne (CHUV), Lausanne, Switzerland RMS Foundation, Bettlach, Switzerland Department for Orthopaedics and Trauma Surgery, Clinic for Orthopaedics and Trauma Surgery, Kantonsspital Baselland Liestal, Rheinstreet 26, Liestal, 4410, Switzerland Department of Traumatology and Reconstructive Surgery including Department of Orthopaedic Surgery, Charité Universitätsmedizin Berlin, Berlin, Germany AU - Furustrand Tafin, U. AU - Betrisey, B. AU - Bohner, M. AU - Ilchmann, T. AU - Trampuz, A. AU - Clauss, M. DB - Scopus DO - 10.1007/s10856-015-5467-6 IS - 3 M3 - Article N1 - Cited By :14 Export Date: 10 November 2020 PY - 2015 ST - Staphylococcal biofilm formation on the surface of three different calcium phosphate bone grafts: a qualitative and quantitative in vivo analysis T2 - Journal of Materials Science: Materials in Medicine TI - Staphylococcal biofilm formation on the surface of three different calcium phosphate bone grafts: a qualitative and quantitative in vivo analysis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84923327479&doi=10.1007%2fs10856-015-5467-6&partnerID=40&md5=e6f047bfc85d7fbf969ae334624e09b3 VL - 26 ID - 1247 ER - TY - JOUR AB - The article focuses on the significance of standardization in the operating room (OR) to avoid retained items in the U.S. Topics discussed include the standardize count policies for procedures, the surgical patient safety project, the standardized management of outpatient surgery programs, and the standardized layout. AN - 113709220. Language: English. Entry Date: 20160316. Revision Date: 20160318. Publication Type: Article. Journal Subset: Biomedical DB - ccm DP - EBSCOhost IS - 4 KW - Retained Instruments -- Prevention and Control Hospital Policies Surgicenters Surgical Count Procedure -- Standards Practice Guidelines Joint Commission AORN Policy and Procedure Manuals N1 - Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 7810150. PY - 2016 SN - 0190-5066 SP - 41-42 ST - Standardization is critical to avoid retained items T2 - Same-Day Surgery TI - Standardization is critical to avoid retained items UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=113709220&site=ehost-live&scope=site VL - 40 ID - 770 ER - TY - JOUR AB - Percutaneous nephrostomy (PCN) catheter placement is a commonly performed procedure in the urological practice for various indications like percutaneous nephrolithotomy, pyonephrosis, infected hydronephrosis and after failed attempt of ureteric stenting. The nephrostomy catheter is usually associated with low complication and morbidity rate, but prolonged indwelling nephrostomy tube may be hazardous in some cases. We hereby report a case of squamous cell carcinoma of skin around the PCN, which was attributed to chronic inflammation and persistent irritation from a long-term neglected indwelling nephrostomy catheter for last 3 years. The patient was managed with wide local excision of skin carcinoma and ureterocalicostomy for pelviureteric junction stricture. The authors report the first documented case with aforementioned presentation. © BMJ Publishing Group Limited 2019. AD - Department of Urology, King George's Medical University, Lucknow, Uttar Pradesh, India AU - Sharma, A. AU - Singh, V. AU - Sinha, R. J. AU - Agarwal, S. C7 - e229023 DB - Scopus DO - 10.1136/bcr-2018-229023 IS - 5 KW - catheter care catheterisation skin cancer surgical oncology unwanted effects / adverse reactions M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 ST - Squamous cell carcinoma of skin due to prolonged indwelling percutaneous nephrostomy catheter T2 - BMJ Case Reports TI - Squamous cell carcinoma of skin due to prolonged indwelling percutaneous nephrostomy catheter UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85066106564&doi=10.1136%2fbcr-2018-229023&partnerID=40&md5=b8454d2be483d2c13764c6bbfcfca45c VL - 12 ID - 1016 ER - TY - JOUR AB - The authors aim to report a 68-year-old patient presenting with acute swelling and redness of orbital area diagnosed initially as orbital cellulitis. Surgical excision was decided based on clinical and imaging findings with the diagnosis of pleomorphic adenoma of the lacrimal gland. Lacrimal gland pleomorphic adenoma usually presents with painless gradual swelling of upper eyelid. In an exceptionally rare circumstance, this case showed acute orbital inflammation, and imaging findings of orbital inflammation mostly focused around the cystic space of the lacrimal gland tumor. Histologic evaluation confirmed a ruptured cystic space of pleomorphic adenoma with foreign body–type inflammatory reaction. The authors propose spontaneous rupture of cystic space in the lacrimal gland pleomorphic adenoma as underlying mechanism for acute presentation of this tumor. Imaging and clinical characteristics and also prognostic implication of this phenomenon are discussed. Copyright © 2017 The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc. AD - Ophthalmic Plastic and Reconstructive Surgery Department, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran Eye Research Center, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran Pathology Department, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran AU - Pakdel, F. AU - Pirmarzdashti, N. AU - Soltani, S. AU - Nozarian, Z. AU - Amoli, F. A. AU - Kassaee, A. DB - Scopus DO - 10.1097/IOP.0000000000001005 IS - 2 M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 SP - e41-e43 ST - Spontaneous rupture of lacrimal gland pleomorphic adenoma: Pivotal role in masquerading orbital cellulitis T2 - Ophthalmic Plastic and Reconstructive Surgery TI - Spontaneous rupture of lacrimal gland pleomorphic adenoma: Pivotal role in masquerading orbital cellulitis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85050663247&doi=10.1097%2fIOP.0000000000001005&partnerID=40&md5=81597c4da2f3ead98153de435bcbd49e VL - 34 ID - 1086 ER - TY - JOUR AB - BACKGROUND: Pneumothorax is one of the respiratory toxic effects of cocaine inhalation. The literature counts several cases, some associated to other respiratory conditions such as pneumomediastinum, haemoptysis and others not requiring surgical treatment. AIM: We present a series of nonHIV cocaine-inhaler subjects who underwent video-assisted thoracoscopic surgery (VATS) for isolated spontaneous pneumothorax. DESIGN: Nine subjects, with a mean age of 24 ± 4 years, admitting cocaine inhalation, developed spontaneous pneumothorax and underwent 10 surgical treatments by means of VATS, at our Institution. RESULTS: Previous pneumothorax occurred in six cases episodes ranged from 0 to 5 (mean 1.6 ± 1.6). Chest computed tomography (CT) scan showed abnormalities in seven cases. All subjects underwent lung apicectomy, apical pleurectomy and mechanical pleurodesis. Seven subjects had also bullectomy. In all cases the visceral pleura was partially covered by fibrinous exudate. Histology of the lung showed small foreign body granulomatous inflammation in fibrotic and/or emphysematous pulmonary parenchyma. Relapse of pneumothorax occurred in one subject at 60 days and it was surgically treated. Mean follow-up was 150 ± 38 months (range 120-239). All subjects are now well, with no evidence of pneumothorax. CONCLUSIONS: Spontaneous pneumothorax in cocaine-inhaler subjects is a reality of which physicians need to be aware. Chest CT scan might not reveal abnormalities. Macroscopically the lung might presents bullae and/or peculiar visceral pleura. Foreign body granulomas observed in the specimens suggest that the particulate component of inhaled substances can injure the lung. Surgical treatment of the bullous disease and mechanical pleurodesis can provide a long-term follow-up without relapse of pneumothorax. AD - Department of Thoracic Surgery. Department of Pathology, Scientific Institute and University Vita-Salute San Raffaele, Ospedale San Raffaele, Milan, Italy. AN - 30895319 AU - Ciriaco, P. AU - Rossetti, F. AU - Carretta, A. AU - Sant'Angelo, M. AU - Arrigoni, G. AU - Negri, G. DA - Jul 1 DO - 10.1093/qjmed/hcz070 DP - NLM ET - 2019/03/22 IS - 7 KW - Administration, Inhalation Adult Cocaine/administration & dosage/*adverse effects Cocaine-Related Disorders/*complications/diagnosis Female Foreign Bodies/complications/diagnosis/pathology Humans Italy Male Pneumothorax/etiology/*surgery Recurrence Retrospective Studies *Thoracic Surgery, Video-Assisted Tomography, X-Ray Computed Treatment Outcome Young Adult LA - eng N1 - 1460-2393 Ciriaco, P Rossetti, F Carretta, A Sant'Angelo, M Arrigoni, G Negri, G Journal Article England QJM. 2019 Jul 1;112(7):519-522. doi: 10.1093/qjmed/hcz070. PY - 2019 SN - 1460-2393 SP - 519-522 ST - Spontaneous pneumothorax in cocaine users T2 - Qjm TI - Spontaneous pneumothorax in cocaine users VL - 112 ID - 225 ER - TY - JOUR AB - Spontaneous hepatic rupture is a rare but life-threatening complication of pregnancy. Case Report: A 30-year-old woman with multi-para pregnancy was admitted to the hospital at 31+3 weeks of gestation who complained of abdominal pain localized in the right upper quadrant on the third day after admission. HELLP syndrome was diagnosed, and emergency cesarean section was performed. Within several hours, blood biochemistry revealed significant elevated liver enzymes and reduced platelet (PLT) count. HELLP syndrome was diagnosed and emergency cesarean section was performed. The authors also made a literature review on the reported cases with spontaneous hepatic rupture during pregnancy in mainland China. A total 39 cases were found. Maternal survival was 78.9% (30/38) and perinatal survival was 50% (21/42). Deaths occurred mainly due to disseminated intravascular coagulation (DIC), acute renal failure, respiratory failure, and so on. An emergency physician should be aware that early evaluation, appropriate diagnosis, and prompt surgical intervention are crucial to deal with such a life-threatening emergency. Multidisciplinary cooperation between obstetricians, surgeons, and pediatricians is required for treating spontaneous hepatic rupture during pregnancy. AD - H. Cui, Obstetrics Department, Tianjin Central Obstetrics and Gynecology Hospital, No. 156, Nankai District, Tianjin, China AU - Ma, B. AU - Cui, H. AU - Chen, X. DB - Embase DO - 10.12891/ceog3944.2018 IS - 2 KW - compression bandage hemostatic sponge alanine aminotransferase antihypertensive agent aspartate aminotransferase bilirubin blood clotting factor 7 cholinesterase fresh frozen plasma hemoglobin lactate dehydrogenase adult alanine aminotransferase blood level antihypertensive therapy Apgar score article aspartate aminotransferase blood level bilirubin blood level bleeding blood biochemistry case report cesarean section cholinesterase blood level clinical article elevated blood pressure emergency surgery erythrocyte transfusion female gestational age headache HELLP syndrome hemoglobin blood level hemostasis hepatomegaly hospital admission human hypertransaminasemia lactate dehydrogenase blood level liver necrosis liver rupture multipara pain severity parenteral nutrition peroperative complication platelet count postoperative care spontaneous hepatic rupture thrombocyte transfusion upper abdominal pain LA - English M3 - Article N1 - L622338579 2018-06-01 2018-06-05 PY - 2018 SN - 0390-6663 SP - 292-295 ST - Spontaneous hepatic rupture during emergency cesarean section in a patient with HELLP syndrome: A case report and literature review T2 - Clinical and Experimental Obstetrics and Gynecology TI - Spontaneous hepatic rupture during emergency cesarean section in a patient with HELLP syndrome: A case report and literature review UR - https://www.embase.com/search/results?subaction=viewrecord&id=L622338579&from=export http://dx.doi.org/10.12891/ceog3944.2018 VL - 45 ID - 354 ER - TY - JOUR AB - Spontaneous gastric perforation is rare in children. It is usually associated with prematurity, foreign bodies and trauma. Anorexia nervosa (AN) can be an underlying condition although no cases are reported in the literature. We are reporting a rare case of 1- year-old boy with AN who presented with right iliac fossa (RIF) pain mimicking acute appendicitis. Intraoperative findings proved a gastric perforation. Pathophysiology of this condition in AN is poorly understood. Gastric smooth muscle atrophy and ischaemia can be the possible underlying mechanisms. The case discussed here highlights the fact that any abdominal pain in patients with underlying eating disorders (EDs) should raise suspicion of perforation as diagnosis can be far more complicated. Copyright 2012 BMJ Publishing Group. All rights reserved. AD - Department of General Surgery, Royal Glamorgan Hospital, Pontyclun, United Kingdom AU - Hashmi, K. S. AU - Ellul, T. AU - Leopard, D. C. AU - Woodward, A. DB - Scopus DO - 10.1136/bcr-2012-006512 M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2012 ST - Spontaneous gastric perforation in an 11-year-old boy with anorexia nervosa: Rare presentation with right iliac fossa pain T2 - BMJ Case Reports TI - Spontaneous gastric perforation in an 11-year-old boy with anorexia nervosa: Rare presentation with right iliac fossa pain UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84867175398&doi=10.1136%2fbcr-2012-006512&partnerID=40&md5=621e9d81557315ec37e5d3ff5ba1abea ID - 1355 ER - TY - JOUR AN - 109793401. Language: English. Entry Date: 20150611. Revision Date: 20161213. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 2 KW - Retained Instruments -- Prevention and Control Surgical Count Procedure Surgical Sponges United States Centers for Medicare and Medicaid Services Surgery, Elective -- Economics N1 - brief item. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 7810150. PY - 2015 SN - 0190-5066 SP - 20-20 ST - Sponges retained in patients during surgery are reduced by 93% in study T2 - Same-Day Surgery TI - Sponges retained in patients during surgery are reduced by 93% in study UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109793401&site=ehost-live&scope=site VL - 39 ID - 819 ER - TY - JOUR AB - Background: Postoperative retained foreign bodies [RFBs] can be a serious event, but they are rare. The x-ray is the current gold standard to detect RFBs. There has been scant research on the process of detection as opposed to the consequence of RFBs. Surgical sponges incorporating automatic data identity capture technology (radiofrequency tags, barcodes) have been proposed to detect RFBs. Because resources in healthcare are scarce, careful consideration needs to be given to developing the right technology in order to maximize the process of RFB elimination. There have been few studies that identify factors contributing to the process of RFB detection. Study design: Our goal was to determine the frequency with which x-rays were ordered to detect abdominal surgery post operative RFBs and the indications for ordering them. We reviewed the Johns Hopkins Hospital's Department of Radiology database to retrospectively study the demographic and radiologic data on patients who underwent exploratory surgery for RFBs following abdominal procedures performed between April 2004 and April 2008. Results: Of the 13,335 portable abdominal x-rays taken during the period, 203 (1.5%) were ordered to assess patients for the presence of an RFB. Of these, 57 (28%) were taken because no RFB count was made (e.g., for emergency procedures), 57 (28%) were taken per procedure or protocol, 51 (25%) were taken because of an incorrect instrument count, and 39 (19%) were taken because of an incorrect sponge count. Of the 203 x-rays, 192 (95%) were negative for RFBs, 11 (5%) were positive or had suspicious findings, and of these 3 (2%) revealed more than 1 RFB. The 11 patients with positive or suspicious findings underwent exploratory procedures immediately during the same operation; of these, 8 (72%) actually had an RFB and 3 (28%) had a negative result at exploration. Conclusion: Multiple pathways lead to the decision to obtain X-rays for RFBs, of which sponges/Incorrect sponge counts make up only one in five. Therefore, technology that focuses on sponges alone may not majorly impact clinical outcome because x-rays will still be required in the majority of cases of suspected high risk. AD - Department of Surgery, School of Medicine, Johns Hopkins Medical Institute, Baltimore, MD, USA. AN - 23949162 AU - Obasi, C. AU - Etienne-Cummings, R. AU - Lehmann, H. AU - Lewin, J. S. AU - Asiyanbola, B. DA - Sep 6 DO - 10.3233/thc-2012-0688 DP - NLM ET - 2013/08/21 LA - eng N1 - 1878-7401 Obasi, Chidi Etienne-Cummings, Ralph Lehmann, Harold Lewin, Jonathan S Asiyanbola, B Journal Article Netherlands Technol Health Care. 2012 Sep 6. doi: 10.3233/THC-2012-0688. PY - 2012 SN - 0928-7329 ST - Sponges and incorrect sponge count: Minor contributions to the process of detecting retained foreign bodies T2 - Technol Health Care TI - Sponges and incorrect sponge count: Minor contributions to the process of detecting retained foreign bodies ID - 140 ER - TY - JOUR AB - The article reports on the risk-sharing program of Kalamazoo, Michigan-based Stryker Corp. that protects investment in the medical technology firm's SurgiCount Safety-Sponge System which guarantees product-liability compensation and a rebate of the SurgiCounter scanning device implementation cost. AN - 115453058. Language: English. Entry Date: 20160524. Revision Date: 20160524. Publication Type: Article DB - ccm DP - EBSCOhost IS - 6 KW - Surgical Count Procedure Retained Instruments -- Prevention and Control Product Evaluation Bar Coding N1 - brief item. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 7810150. PY - 2016 SN - 0190-5066 SP - 70-70 ST - Sponge counting system backed with guarantee plus $5 million indemnity protection T2 - Same-Day Surgery TI - Sponge counting system backed with guarantee plus $5 million indemnity protection UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=115453058&site=ehost-live&scope=site VL - 40 ID - 805 ER - TY - JOUR AN - 3852351 AU - Tammeleo, A. D. DA - Oct DP - NLM ET - 1985/10/01 IS - 5 KW - Abdomen *Foreign Bodies Gallbladder Diseases/surgery Humans Louisiana Male Operating Room Nursing/*legislation & jurisprudence Rupture/surgery *Surgical Equipment LA - eng N1 - Tammeleo, A D Case Reports Journal Article United States Regan Rep Nurs Law. 1985 Oct;26(5):4. PY - 1985 SN - 0034-3196 (Print) 0034-3196 SP - 4 ST - Sponge count botched--discovery & silence. Case in point: Simon v. Smith (470 So. 2d 941 - LA) T2 - Regan Rep Nurs Law TI - Sponge count botched--discovery & silence. Case in point: Simon v. Smith (470 So. 2d 941 - LA) VL - 26 ID - 10 ER - TY - JOUR AN - 105436441. Language: English. Entry Date: 20091016. Revision Date: 20150711. Publication Type: Journal Article AU - Gibbs, V. C. DB - ccm DP - EBSCOhost KW - Patient Safety Retained Instruments -- Prevention and Control Surgical Count Procedure -- Equipment and Supplies N1 - protocol. Supplement Title: Sep2009 Supplement 1. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2009 SN - 0190-5066 SP - 1-1 ST - Sponge ACCOUNTing System: use of plastic hanging sponge-holders and a dry erase board T2 - Same-Day Surgery TI - Sponge ACCOUNTing System: use of plastic hanging sponge-holders and a dry erase board UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105436441&site=ehost-live&scope=site ID - 928 ER - TY - JOUR AB - Spondylodiscitis is a rare complication of unwitnessed button battery ingestion in children. We report a case of a 20-month-old girl who presented to the emergency room 2 weeks after endoscopic removal of unwitnessed, impacted esophageal battery. Delayed presentation of spondylodiscitis after foreign body removal is related to local injury, pressure necrosis, and perforation. The bilaminar shape of an unknown ingested foreign body should alert the treating physician that it might be a battery rather than a coin. Prompt evaluation with magnetic resonance imaging is essential to prevent neurological deficit and/or spinal deformities. © The Author(s) 2015. AD - Section of Pediatric Neuroradiology, Division of Pediatric Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins School of Medicine, Charlotte R. Bloomberg Children's Center, Sheikh Zayed Tower, 1800 Orleans Street, Baltimore, MD 21287-0842, United States AU - Young, A. AU - Tekes, A. AU - Huisman, T. A. G. M. AU - Bosemani, T. DB - Scopus DO - 10.1177/1971400915611142 IS - 5 KW - button battery ingestion children magnetic resonance imaging Spondylodiscitis M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2015 SP - 504-507 ST - Spondylodiscitis associated with button battery ingestion: Prompt evaluation with MRI T2 - Neuroradiology Journal TI - Spondylodiscitis associated with button battery ingestion: Prompt evaluation with MRI UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84946564582&doi=10.1177%2f1971400915611142&partnerID=40&md5=7342fa68317e49757ac746f44d567160 VL - 28 ID - 1218 ER - TY - JOUR AD - General and Endocrine Surgery Department, Lille University Hospital, Lille, France French National Institute of Health and Medical Research-INSERM UMR 859, Diabetes Cell Therapy, Lille, France Université Lille Nord de France, Lille, France AU - Genser, L. AU - Pattou, F. AU - Caiazzo, R. DB - Scopus DO - 10.1016/j.soard.2015.07.017 IS - 1 KW - Aeroportia Endoscopic internal drainage Hepatic portal splenic venous gas Leak Migration Pigtail Sleeve M3 - Article N1 - Cited By :9 Export Date: 10 November 2020 PY - 2016 SP - e1-e3 ST - Splenic abscess with portal venous gas caused by intrasplenic migration of an endoscopic double pigtail drain as a treatment of post-sleeve gastrectomy fistula T2 - Surgery for Obesity and Related Diseases TI - Splenic abscess with portal venous gas caused by intrasplenic migration of an endoscopic double pigtail drain as a treatment of post-sleeve gastrectomy fistula UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84959530687&doi=10.1016%2fj.soard.2015.07.017&partnerID=40&md5=8dc84fd1386e73873ed608c11ab3a3f5 VL - 12 ID - 1201 ER - TY - JOUR AU - Kauffman, H. M. AU - Swanson, M. K. AU - McGregor, W. R. AU - Rodgers, R. E. AU - Fox, P. S. DB - Scopus IS - 1 M3 - Article N1 - Cited By :21 Export Date: 10 November 2020 PY - 1974 SP - 33-40 ST - Splenectomy in renal transplantation T2 - Surgery Gynecology and Obstetrics TI - Splenectomy in renal transplantation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0016089067&partnerID=40&md5=ecc8d80bd747c1f28db17266cfc1662d VL - 139 ID - 1775 ER - TY - JOUR AB - BACKGROUND: Textile products commonly used in surgery (e.g., sponges or gauze) have been known to cause complications after spinal surgery. Associated complications usually arise months or even years after the primary surgery. In case of spine surgery, these bodies are often detected during neuroradiological evaluations to investigate reported back pain; however, this complication often remains asymptomatic. AIMS: The research is intended to increase awareness among both spinal surgeons and neuroradiologists of this potential complication. STUDY DESIGN: Retrospective study. METHODS: This study is a retrospective case series of three patients with retained surgical textile products who had been misdiagnosed with spinal tumour. The medical records of the patients were reviewed and demographic data, clinical aspects, initial diagnosis, surgical procedures, time interval between previous operation and onset of symptoms, laboratory findings, radiological findings, treatment, and outcome were analysed. RESULTS: The three patients included two women and one man aged between 64 and 67 years. All patients had a previous surgery for lumbar disc herniation. The time from the previous surgical procedures to presentation ranged from 3 to 17 years. All patients presented with non-specific lower back pain and/or radiculopathy without clinical findings of infection. Laboratory parameters were otherwise normal. All three cases had been misdiagnosed as a spinal tumor based on magnetic resonance imaging findings. During new surgical procedures, gauze bandages, i.e., surgical textiles left during a previous operation, were found. CONCLUSION: Textiloma is an important and rarely mentioned potential neurosurgical complication that may remain asymptomatic for years. They are more common in obese patients, after emergency surgery, and with unplanned changes in surgical procedure such as bleeding and unintended neurosurgical complications. Neuroradiological findings are variable and non-specific; thus, patients could be misdiagnosed with a spinal tumor or abscess. Likewise, in patients with a history of spinal surgery, spinal abscesses, haematomas, hypertrophic scars, fibrosarcomas, rhabdomyosarcomas, and schwannomas should definitely be considered in the differential diagnosis and considered when planning diagnostic procedures. Appropriate antibiotic therapy is recommended when a suppurative complication is present or suspected. Textiloma is a medico-legal complication that can be prevented by the education of surgical staff, the counting method (preoperatively, at closure, and at the end), and use of products with radiopaque barcodes. AD - Department of Neurosurgery, Kocaeli Derince Research and Teaching Hospital, Kocaeli, Turkey. Department of Neurosurgery, Gülhane Military Academy Haydarpaşa Training Hospital, İstanbul, Turkey. Department of Neurosurgery, Ümraniye Research and Teaching Hospital, İstanbul, Turkey. AN - 25207152 AU - Sahin, S. AU - Atabey, C. AU - Simşek, M. AU - Naderi, S. C2 - PMC4115950 DA - Dec DO - 10.5152/balkanmedj.2013.8732 DP - NLM ET - 2014/09/11 IS - 4 KW - Gauze bandage foreign body granuloma gossypiboma lumbar spine spinal tumour surgical textile products LA - eng N1 - 2146-3131 Sahin, Soner Atabey, Cem Simşek, Mehmet Naderi, Sait Journal Article Balkan Med J. 2013 Dec;30(4):422-8. doi: 10.5152/balkanmedj.2013.8732. Epub 2013 Dec 1. PY - 2013 SN - 2146-3123 (Print) 2146-3123 SP - 422-8 ST - Spinal textiloma (gossypiboma): a report of three cases misdiagnosed as tumour T2 - Balkan Med J TI - Spinal textiloma (gossypiboma): a report of three cases misdiagnosed as tumour VL - 30 ID - 154 ER - TY - JOUR AB - Background: Textile products commonly used in surgery (e.g., sponges or gauze) have been known to cause complications after spinal surgery. Associated complications usually arise months or even years after the primary surgery. In case of spine surgery, these bodies are often detected during neuroradiological evaluations to investigate reported back pain; however, this complication often remains asymptomatic. Aims: The research is intended to increase awareness among both spinal surgeons and neuroradiologists of this potential complication. Study Design: Retrospective study. Methods: This study is a retrospective case series of three patients with retained surgical textile products who had been misdiagnosed with spinal tumour. The medical records of the patients were reviewed and demographic data, clinical aspects, initial diagnosis, surgical procedures, time interval between previous operation and onset of symptoms, laboratory findings, radiological findings, treatment, and outcome were analysed. Results: The three patients included two women and one man aged between 64 and 67 years. All patients had a previous surgery for lumbar disc herniation. The time from the previous surgical procedures to presentation ranged from 3 to 17 years. All patients presented with non-specific lower back pain and/or radiculopathy without clinical findings of infection. Laboratory parameters were otherwise normal. All three cases had been misdiagnosed as a spinal tumor based on magnetic resonance imaging findings. During new surgical procedures, gauze bandages, i.e., surgical textiles left during a previous operation, were found. Conclusion: Textiloma is an important and rarely mentioned potential neurosurgical complication that may remain asymptomatic for years. They are more common in obese patients, after emergency surgery, and with unplanned changes in surgical procedure such as bleeding and unintended neurosurgical complications. Neuroradiological findings are variable and non-specific; thus, patients could be misdiagnosed with a spinal tumor or abscess. Likewise, in patients with a history of spinal surgery, spinal abscesses, haematomas, hypertrophie scars, fibrosarcomas, rhabdomyosarcomas, and schwannomas should definitely be considered in the differential diagnosis and considered when planning diagnostic procedures. Appropriate antibiotic therapy is recommended when a suppurative complication is present or suspected. Textiloma is a medico-legal complication that can be prevented by the education of surgical staff, the counting method (preoperatively, at closure, and at the end), and use of products with radiopaque barcodes. AD - Department of Neurosurgery, Kocaeli Derince Research and Teaching Hospital, Kocaeli, Turkey Department of Neurosurgery, Gülhane Military Academy Haydarpaşa Training Hospital, İstanbul, Turkey Department of Neurosurgery, Ãmraniye Research and Teaching Hospital, İstanbul, Turkey AN - 104029403. Language: English. Entry Date: 20140225. Revision Date: 20200708. Publication Type: Journal Article AU - Şahin, Soner AU - Atabey, Cem AU - Şimşek, Mehmet AU - Naderi, Sait DB - ccm DO - 10.5152/balkanmedj.2013.8732 DP - EBSCOhost IS - 4 KW - Spinal Neoplasms Spine -- Surgery Postoperative Complications -- Diagnosis Retained Instruments -- Diagnosis Low Back Pain -- Etiology Granuloma -- Radiography Human Retrospective Design Diagnosis, Differential Aged Textiles Bandages and Dressings Female Magnetic Resonance Imaging Male N1 - case study; diagnostic images; pictorial; research. Journal Subset: Biomedical; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Middle East. NLM UID: 9426241. PY - 2013 SN - 2146-3123 SP - 422-428 ST - Spinal Textiloma (Gossypiboma): A Report of Three Cases Misdiaanosed as Tumour T2 - Balkan Medical Journal TI - Spinal Textiloma (Gossypiboma): A Report of Three Cases Misdiaanosed as Tumour UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104029403&site=ehost-live&scope=site VL - 30 ID - 779 ER - TY - JOUR AB - Immune defense is a key feature in the life history of organisms, expensive to maintain, highly regulated by individuals and exposed to physiological and evolutionary trade-offs. In chelicerates, relatively scarce are the studies that relate postcopulatory mechanisms and immune response parameters. This work makes an approximation to the female's immunological consequences produced after the placement of a foreign body in the genitalia of three scorpions species, two species that normally receive genital plugs during mating (Urophonius brachycentrus and U. achalensis) and one that does not (Zabius fuscus). Here we performed the first morphological description of the natural plugs of the two Urophonius species. We described complex three zoned structure anchored to the female genital atrium and based on this information we placed implants in the genitalia (for eliciting the local immune response) of virgin females of the three species and measured the immune encapsulation response to this foreign body. We found a greater and heterogeneous response in different zones of the implants in the plug producing species. To corroborate the specificity of this immune response, we compared the local genital reaction with the triggered response at a systemic level by inserting implants into the female body cavity of U. brachycentrus and Zabius fuscus. We found that the systemic response did not differ between species and that only in the plug producing species the local response in the genitalia was higher than the systemic one. We also compared the total hemocyte load before and after the genital implantation to see if this parameter was compromised by the immunological challenge. We confirmed that in Urophonius species the presence of a strange body in the genitalia caused a decrease in the hemocyte load. Besides, we find correlations between the body weight and the immunological parameters, as well as between different immunological parameters with each other. Complementarily, we characterized the hemocytes of the three scorpion species for the first time. This comparative study can help to provide a wider framework of the immunological characteristics of the species, their differences and their relationship with the particular postcopulatory mechanism such as the genital plugs. © 2019 Oviedo-Diego et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. AD - Universidad Nacional de Córdoba, Facultad de Ciencias Exactas, Físicas y Naturales, Departamento de Diversidad Biológica y Ecología, Córdoba Capital, Córdoba, Argentina Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Diversidad y Ecología Animal (IDEA), Laboratorio de Biología Reproductiva y Evolución, Córdoba Capital, Cordoba, Argentina AU - Oviedo-Diego, M. A. AU - Mattoni, C. I. AU - Peretti, A. V. C7 - e0208682 DB - Scopus DO - 10.1371/journal.pone.0208682 IS - 2 M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2019 ST - Specificity of the female's local cellular immune response in genital plug producing scorpion species T2 - PLoS ONE TI - Specificity of the female's local cellular immune response in genital plug producing scorpion species UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85061363742&doi=10.1371%2fjournal.pone.0208682&partnerID=40&md5=15f11ccf411847d9f575c087626394a8 VL - 14 ID - 1025 ER - TY - JOUR AN - 108157762. Language: English. Entry Date: 20120309. Revision Date: 20201001. Publication Type: journal article AU - Grissinger, Mathew AU - Grissinger, Matthew DB - ccm DP - EBSCOhost IS - 1 KW - Hospitals Medication Errors -- Prevention and Control Protocols Health Facility Administration Patient Identification Surgical Count Procedure Treatment Errors -- Prevention and Control N1 - pictorial. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9015516. PMID: NLM22346329. PY - 2012 SN - 1052-1372 SP - 4-5 ST - Some Red Rules Shouldn't Rule In Hospitals T2 - P&T: A Peer-Reviewed Journal for Managed Care & Formulary Management TI - Some Red Rules Shouldn't Rule In Hospitals UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108157762&site=ehost-live&scope=site VL - 37 ID - 895 ER - TY - JOUR AD - State Volunteer Mutual Insurance Company, Brentwood, USA. AN - 19791539 AU - Avery, J. K. DA - Sep DP - NLM ET - 2009/10/02 IS - 9 KW - Adult Female Foreign Bodies/*economics/surgery Humans Liability, Legal/*economics Malpractice/*economics Pelvic Pain Postoperative Complications/*economics Surgical Instruments Surgical Sponges LA - eng N1 - Avery, J Kelley Case Reports Journal Article United States Tenn Med. 2009 Sep;102(9):45. PY - 2009 SN - 1088-6222 (Print) 1088-6222 SP - 45 ST - So who's counting? T2 - Tenn Med TI - So who's counting? VL - 102 ID - 93 ER - TY - JOUR AB - The use of photography is an underreported method of research in the nursing literature. This paper explores its use in an ethnographic research project, the fieldwork of which was undertaken by the first author. The aim was to examine the governance of operating room nursing in the clinical setting and the theoretical orientation was the work of Michel Foucault. The focus of this paper is on how photography was used as a means of data generation. To establish some context we begin by drawing on writers from sociology and anthropology to provide an overview of the status of vision and visual research methods in contemporary social research. We then move to a brief discussion of the uses of photography in social research and the limitations imposed by ethical considerations of its use in clinical nursing settings. As well, the process and approach involved in this research project, and issues of analysis are discussed. Three 'snap-shots' of operating room nursing, taken by participants, are presented. Each is analysed in terms of its contributions to the research process as well as its substantive contribution to the theoretical framework and the research aims. AD - Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Carlton, Australia AN - 106873102. Language: English. Entry Date: 20031010. Revision Date: 20200708. Publication Type: Journal Article AU - Riley, R. AU - Manias, E. DB - ccm DO - 10.1046/j.1440-1800.2003.00166.x DP - EBSCOhost IS - 2 KW - Photography Perioperative Nursing -- Victoria Communication Ethnographic Research Field Studies Theory Observational Methods Photography -- Ethical Issues Research Ethics Unstructured Interview Data Analysis Registered Nurses Operating Rooms Diaries Power Victoria Documentation Nonverbal Communication Telephone Surgical Count Procedure Human N1 - pictorial; research. Journal Subset: Australia & New Zealand; Core Nursing; Nursing; Peer Reviewed. NLM UID: 9505881. PMID: NLM12755857. PY - 2003 SN - 1320-7881 SP - 81-90 ST - Snap-shots of live theatre: the use of photography to research governance in operating room nursing T2 - Nursing Inquiry TI - Snap-shots of live theatre: the use of photography to research governance in operating room nursing UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106873102&site=ehost-live&scope=site VL - 10 ID - 868 ER - TY - JOUR AB - A diagnosis of small-bowel perforation, caused by a sharp or pointed foreign body, is rarely made preoperatively because the clinical symptoms are usually nonspecific and can mimic other surgical conditions, such as appendicitis and diverticulitis. We report the case of a 62-year-old woman who experienced severe pain in the right iliac fossa and fever for about five days before arrival at our hospital. The presumptive diagnosis was acute purulent appendicitis and an emergency appendectomy was planned. Swelling and erythema were noted in a segment of the small bowel in the lower right abdomen. A tiny pointed object was found penetrating the inflamed portion of the bowel, which proved to be a sharp fish bone (gray snapper). The bone was removed, followed by segmental resection of the terminal ileum and ascending colon. The postoperative course was uneventful. © 2005 The WJG Press and Elsevier Inc. All rights reserved. AD - Division of General Surgery, Tri-Service General Hospital, National Defense Medical Center, 325 Section 2 Cheng-Kung Road, Neihu 114 Taipei, Taiwan, Taiwan AU - Hsu, S. D. AU - Chan, D. C. AU - Liu, Y. C. DB - Scopus DO - 10.3748/wjg.v11.i12.1884 IS - 12 KW - Fish bone Small-bowel perforation M3 - Article N1 - Cited By :32 Export Date: 10 November 2020 PY - 2005 SP - 1884-1885 ST - Small-bowel perforation caused by fish bone T2 - World Journal of Gastroenterology TI - Small-bowel perforation caused by fish bone UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-17144420852&doi=10.3748%2fwjg.v11.i12.1884&partnerID=40&md5=b5009a45e140b60c247db359f713d7d8 VL - 11 ID - 1610 ER - TY - JOUR AB - Bezoars are conglomerations of undigested foreign material retained in the gastrointestinal tract. Trichobezoar is a compact conglomeration of swallowed hair and constitutes less than 6% of all bezoars. Their most frequent location is in the stomach but they may extend through the pylorus into the small bowel. This condition is known as Rapunzel syndrome. Many patients may remain asymptomatic or present a mild form of the disease characterized by abdominal pain, early satiety, nausea, and vomiting. Complications may manifest as gastric outlet obstruction or bleeding, and intestinal obstruction. A 15-year-old female patient presented with clinical findings of intestinal obstruction. The patient suffered from depressive and anxiety disorders and trichotillomania, although trichophagy could not be assured. Alopecia circumscripta and irregular hair length on the scalp were identified. A computed tomography (CT) scan showed two images highly suggestive of trichobezoars, one in the stomach and the second one causing obstruction at the ileocecal valve. At laparotomy, both a mobile gastric trichobezoar with a tail extending to the duodenum and a trichobezoar causing obstruction at the ileocecal valve were removed. The postoperative course was uneventful. The passage of a detached trichobezoar fragment in a patient with Rapunzel syndrome may cause intestinal obstruction. CT is the preferred image modality for the evaluation of suspected trichobezoars in order to characterize their size and locations, the presence and level of obstruction, and complications such as ischemia or perforation. A case of small-bowel obstruction secondary to ileal trichobezoar in a patient with Rapunzel syndrome is herein reported. © 2018 The Author(s). Published by S. Karger AG, Basel. AD - Department of General Surgery, Hospital Civil de Guadalajara Fray Antonio Alcalde, Calle Hospital 278, Sector Hidalgo, Guadalajara, Jalisco, CP 44280, Mexico Departamento de Clínicas Quirúrgicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Mexico Department of Radiology, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Mexico AU - García-Ramírez, B. E. AU - Nuno-Guzman, C. M. AU - Zaragoza-Carrillo, R. E. AU - Salado-Rentería, H. AU - Gómez-Abarca, A. AU - Corona, J. L. DB - Scopus DO - 10.1159/000492810 IS - 3 KW - Case report Gastric trichobezoar Intestinal obstruction Rapunzel syndrome Small-bowel trichobezoar Trichobezoar M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2018 SP - 559-565 ST - Small-Bowel Obstruction Secondary to Ileal Trichobezoar in a Patient with Rapunzel Syndrome T2 - Case Reports in Gastroenterology TI - Small-Bowel Obstruction Secondary to Ileal Trichobezoar in a Patient with Rapunzel Syndrome UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85053919467&doi=10.1159%2f000492810&partnerID=40&md5=d6f8ec39a9a982929f75a1dccd460c9d VL - 12 ID - 1067 ER - TY - JOUR AD - Gulhane School of Medicine, Department of Surgery, Ankara, Turkey AU - Kaymak, Ş AU - Şenocak, R. AU - Kılbaş, Z. DB - Scopus DO - 10.4328/JCAM.3179 IS - 3 M3 - Article N1 - Export Date: 10 November 2020 PY - 2016 ST - Yabancı cisim yutma hikayesi olmayan bir hastada cam parçasının yol açtığı İnce barsak perforasyonu T2 - Journal of Clinical and Analytical Medicine TI - Small bowel perforation due to glass particle in a patient without history of swallowed foreign body UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84954057956&doi=10.4328%2fJCAM.3179&partnerID=40&md5=7c9466c899bb4bdebeef760c8c2a09ed VL - 7 ID - 1181 ER - TY - JOUR AD - Division of Surgical Critical Care and Trauma, Department of Surgery, Yonsei University College of Medicine, Seoul, South Korea AU - Jang, J. Y. AU - Shim, H. AU - Lee, J. G. DB - Scopus IS - 4 M3 - Article N1 - Export Date: 10 November 2020 PY - 2013 SP - E145-E146 ST - Small bowel perforation by a germanium stone T2 - American Surgeon TI - Small bowel perforation by a germanium stone UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84876136014&partnerID=40&md5=b98081e44edbea8200ab9aedb4b06439 VL - 79 ID - 1322 ER - TY - JOUR AB - Introduction Small bowel obstruction is a common complication after ileal J-pouch-anal anastomosis (IPAA). Adhesions are the most frequent cause. Foreign body ingestions are uncommon in adults. We report a rare case of a small bowel obstruction in an adult patient with IPAA after coin ingestion. Case Description A 72 year old man with history of refractory ulcerative colitis underwent protocolectomy with ileal J-pouch-anal anastomosis in 1999. He presented to the emergency department in December 2016 with complaint of crampy, lower abdominal pain, nausea and vomiting for two days. He denied any fever or chills. No constipation or diarrhea. Lab studies revealed a normal white blood cell count, normal lipase and normal liver function tests. CT scan of the abdomen revealed a dilatation of the distal ileum measuring 38 mm in diameter, small bowel wall thickening and mesenteric fat stranding proximal to the ilioanal anastomosis. Findings were concerning for small bowel obstruction with transition point at the ilioanal anastomosis. Patient underwent pouchoscopy which revealed erythematous mucosa in the j-pouch and presence of a severe stricture measuring about one cm in length and 7mm in diameter (Figure 1). The stricture was traversed after balloon dilation under fluoroscopic guidance (Figure 2). A United States penny coin was found proximal to the stricture which was retrieved from the j-pouch using a Roth Net® retriever (Figure 3). Patient had resolution of his symptoms after the procedure. Patient might have inadvertently swallowed the coin along with his daily pills which he routinely kept in his pants pocket. Discussion Coin and other foreign body ingestions are common in pediatric population but infrequent in adults. Swallowed items that pass beyond the pylorus are simply observed as they usually pass spontaneously through the gastrointestinal tract. Retained foreign bodies can increase the risk of complications by 50%, including formation of strictures, fistulas, abscesses, perforation, sepsis and death. It is estimated that up to 35% patients with IPAA experience small bowel obstruction most commonly due to extensive adhesions. It is possible that the high zinc content in the penny coin might have contributed to the inflammation and stricture formation in the j-pouch. Our case illustrates that retained foreign bodies can be safely and successfully removed endoscopically in patients with IPAA without need for open surgery. (Figure Presented). AD - A. Ratra, Eisenhower Medical Center, Rancho Mirage, CA, United States AU - Ratra, A. AU - Conti, J. DB - Embase DO - 10.1038/ajg.2017.317 KW - endogenous compound triacylglycerol lipase zinc abdomen abscess adhesion adult aged balloon dilatation case report child chill clinical article complication conference abstract constipation death diarrhea emergency ward fever fistula foreign body gastrointestinal tract human ileal pouch-anal anastomosis ingestion leukocyte count liver function test lower abdominal pain male mesenteric fat mucosa nausea and vomiting open surgery perforation pill pylorus sepsis small intestine obstruction small intestine wall stenosis ulcerative colitis United States x-ray computed tomography LA - English M3 - Conference Abstract N1 - L620839796 2018-03-01 PY - 2017 SN - 1572-0241 SP - S997-S998 ST - Small bowel obstruction in ileal J-pouch from coin ingestion T2 - American Journal of Gastroenterology TI - Small bowel obstruction in ileal J-pouch from coin ingestion UR - https://www.embase.com/search/results?subaction=viewrecord&id=L620839796&from=export http://dx.doi.org/10.1038/ajg.2017.317 VL - 112 ID - 364 ER - TY - JOUR AB - A 73-year-old man presented to the surgical assessment unit with recurrent episodes of central abdominal pain and vomiting for 18 months. He has the past medical history (PMH) of hypertension and has been using his denture for 35 years; he had no past surgical history; he drinks alcohol socially and not a smoker. This patient was investigated for iron deficiency anaemia with upper and lower gastrointestional endoscopy, as the patient had positive faecal occult blood; rectal biopsy showed no sign of inflammation and no evidence of malignancy; blood investigation showed Hb 9.8 g/dl, white cell count 14.8, mean cell volume 86.3, mean cell haemoglobin 26.9 and C reactive protein 13. This patient underwent a CT scan of the chest, abdomen and pelvis; the latest one showed that there is a short segment of the middle part of the small bowel that looks thickened and within which there is a high-density calcified shadow which is reported as an ingested foreign body or a tooth fragment; the patient underwent laparotomy and the histology results revealed 30 mm well differentiated/moderately differentiated adenocarcinoma. AD - Department of General Surgery, University Hospital of Leicester, Leicester, UK. amareltweri@hotmail.com AN - 22689878 AU - Eltweri, A. M. AU - Bowrey, D. AU - Taylor, M. C2 - PMC4543062 DA - Jun 8 DO - 10.1136/bcr.02.2012.5915 DP - NLM ET - 2012/06/13 KW - Adenocarcinoma/*diagnostic imaging/pathology/surgery Aged Diagnosis, Differential Endoscopy, Gastrointestinal Humans Intestinal Neoplasms/*diagnostic imaging/pathology/surgery *Intestine, Small Laparotomy Male *Tomography, X-Ray Computed LA - eng N1 - 1757-790x Eltweri, Amar Mohamed Bowrey, David Taylor, Mark Case Reports Journal Article BMJ Case Rep. 2012 Jun 8;2012:bcr0220125915. doi: 10.1136/bcr.02.2012.5915. PY - 2012 SN - 1757-790x ST - Small bowel adenocarcinoma: a case of atypical CT scan appearance T2 - BMJ Case Rep TI - Small bowel adenocarcinoma: a case of atypical CT scan appearance VL - 2012 ID - 126 ER - TY - JOUR AB - Capsular contracture remains a challenge in plastic surgery and represents one of the most common postoperative complications following alloplastic breast reconstruction. The impact of the surface structure of silicone implants on the foreign body reaction and the behaviour of connective tissue-producing cells has already been discussed. The aim of this study was to investigate different pore sizes of silicone surfaces and their influence on human fibroblasts in an in vitro model. Four different textures (no, fine, medium and coarse texture) produced with the salt-loss technique, have been assessed in an in vitro model. Human fibroblasts were seeded onto silicone sheets and evaluated after 1, 4 and 7 days microscopically, with viability assay and gene expression analysis. Comparing the growth behaviour and adhesion of the fibroblasts on the four different textures, a dense cell layer, good adhesion and bridge-building ability of the cells could be observed for the fine and medium texture. Cell number and viability of the cells were increasing during the time course of experiments on every texture. TGFß1 was lowest expressed on the fine and medium texture indicating a trend for decreased fibrotic activity. For silicone surfaces produced with the salt-loss technique, we were able to show an antifibrotic effect of smaller sized pores. These findings underline the hypothesis of a key role of the implant surface and the pore size and pore structure in preventing capsular contracture. © 2020, The Author(s). AD - Department of Plastic and Hand Surgery and Laboratory for Tissue Engineering and Regenerative Medicine, University Hospital of Erlangen Friedrich-Alexander-University of Erlangen-Nürnberg (FAU), Krankenhausstraße 12, Erlangen, 91054, Germany Institute of Polymer Materials, Friedrich-Alexander-University of Erlangen-Nürnberg (FAU), Martensstrasse 7, Erlangen, 91058, Germany Institute of Medical Biotechnology, Friedrich-Alexander-University of Erlangen-Nürnberg (FAU), Paul-Gordan-Str. 3, Erlangen, 91052, Germany AU - Tolksdorf, J. AU - Horch, R. E. AU - Grüner, J. S. AU - Schmid, R. AU - Kengelbach-Weigand, A. AU - Schubert, D. W. AU - Werner, S. AU - Schneidereit, D. AU - Friedrich, O. AU - Ludolph, I. C7 - 23 DB - Scopus DO - 10.1007/s10856-020-6360-5 IS - 2 M3 - Article N1 - Export Date: 10 November 2020 PY - 2020 ST - Size matters—in vitro behaviour of human fibroblasts on textured silicone surfaces with different pore sizes T2 - Journal of Materials Science: Materials in Medicine TI - Size matters—in vitro behaviour of human fibroblasts on textured silicone surfaces with different pore sizes UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85078921046&doi=10.1007%2fs10856-020-6360-5&partnerID=40&md5=7cfb22f5b53fef3e75647f34c5fba3b1 VL - 31 ID - 975 ER - TY - JOUR AB - Objectives: Estimate the cost-effectiveness of utilizing the SituateTM radiofrequency (RF) Detection System plus manual tracking of surgical sponges versus manual tracking alone, to prevent the incidence of retained surgical sponges (RSS). Methods: We developed a one-year decision analytic model to assess the clinical and economic impacts of utilizing SituateTM Detection System to prevent RSS in a surgical facility performing 10,000 surgeries annually, using inputs from literature and clinical expert opinion. We estimated the incremental costs per RSS avoided by modeling the following parameters: counting discrepancy rates; diagnostic performance of SituateTM Detection System, manual counting, and intraoperative radiographs; time associated with searching inside/outside the surgical field and waiting for/reading radiographs; and cost of operating room (OR) time, radiographs, RF-tagged sponges and SituateTM Detection System wand covers, and infections, unreimbursed procedure, and legal costs associated with RSS. Model parameters were varied through one-way sensitivity and scenario analyses to test the robustness of model results. Results: Under base case assumptions, SituateTM Detection System dominated manual counting alone by preventing 2 additional RSS while resulting in $620,789 fewer costs. Cost reductions were due to the efficiencies gained by using the device, lower utilization of radiographs, and fewer medical/legal costs resulting from RSS. Model results were robust to the sensitivity analyses. Even with legal costs removed from the model, which was by far the greatest cost, to conservatively reflect an ex-U. S. medical malpractice landscape, SituateTM Detection System still reduced costs by $65,448 and continued to dominate manual counting. Conclusions: The implications of RSS can be both clinically and economically significant for patients and healthcare facilities, and the literature suggests that standard manual counting is not optimal in preventing RSS. Our model suggests that, even using conservative estimates, SituateTM Detection System can avert medical and legal costs, decrease unproductive OR time, and most importantly, more effectively prevent RSS. AD - B. Leinwand, Avalere Health LLC, Washington, DC, United States AU - Leinwand, B. AU - Hughes, K. E. DB - Embase IS - 7 KW - diagnostic value disease simulation human infection landscape malpractice operating room radiofrequency surgery surgical sponge X ray film LA - English M3 - Conference Abstract N1 - L613235687 2016-11-21 PY - 2016 SN - 1524-4733 SP - A705 ST - The situate detection system-a cost-effective approach to preventing retained surgical sponges T2 - Value in Health TI - The situate detection system-a cost-effective approach to preventing retained surgical sponges UR - https://www.embase.com/search/results?subaction=viewrecord&id=L613235687&from=export VL - 19 ID - 388 ER - TY - JOUR AB - Implantation of any medical device normally causes an inflammatory cell interaction with the foreign material. In vitro cell activation of human neutrophils (Mac-1 upregulation) has been taken as one measure to assess the attributable risk of inflammation due to biopolymers before their clinical application. Mac-1 expression has generally been measured by flow cytometric assays, whereas quantification of neutrophil adhesion to the biopolymer surfaces has been performed by separate and time-consuming assays, e.g. microscopically by differential cell counting. However, due to an increasing number of surface-modified novel biopolymers entering clinical usage, effective testing of their inflammatory potential is now mandatory. To facilitate these analyses, we have developed a novel flow cytometric assay permitting simultaneous measurement of biopolymer-mediated neutrophil activation and adhesion. The biopolymers were used as beads (diameter 25 ± 10 μm), and were demonstrated to be non-phagocytosable and non-fluorescent before being co-incubated with whole human blood (range of ratio granulocytes/beads from 5:1 to 1:1). Besides flow cytometric measurement of Mac-1 up-regulated neutrophils as fluorescing events, a fluorescence of the bead population indicates the adherence of activated neutrophils to the biopolymer surface. After establishing this assay, we evaluated it by comparing six different biopolymers. We observed high levels of Mac-1 expression (> 70% of positive control) accompanied by increased adhesiveness (> 60% of neutrophils) for polyurethane (PUR), polymethylmetacrylate (PMMA), and poly-DL-lactide (PDLLA) beads. Low Mac-1 expression levels (< 10%) accompanied by a low percentage of adhering neutrophils (< 10%) were observed for polyethylene (PE), polyisoprene (PI), and silicone (SI) beads. © 2001 Elsevier Science B.V. All rights reserved. AD - Institute of Medical Microbiology, University Hospital RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Germany Institute of Medical Immunology, University Hospital RWTH Aachen, 52057 Aachen, Germany AU - Peltroche-Llacsahuanga, H. AU - Schmidt, S. AU - Schnitzler, N. AU - Lütticken, R. AU - Haase, G. DB - Scopus DO - 10.1016/S0022-1759(01)00468-9 IS - 1-2 KW - Adhesion Biomaterials Flow cytometry Mac-1 Neutrophils M3 - Article N1 - Cited By :17 Export Date: 10 November 2020 PY - 2001 SP - 13-25 ST - Simultaneous measurement of biopolymer-mediated Mac-1 up-regulation and adherence of neutrophils: A novel flow cytometric approach for predicting initial inflammatory interaction with foreign materials T2 - Journal of Immunological Methods TI - Simultaneous measurement of biopolymer-mediated Mac-1 up-regulation and adherence of neutrophils: A novel flow cytometric approach for predicting initial inflammatory interaction with foreign materials UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035545594&doi=10.1016%2fS0022-1759%2801%2900468-9&partnerID=40&md5=866c6220d4b2d6adb04b89bd67748f16 VL - 258 ID - 1667 ER - TY - JOUR AB - Purpose: Previous research has identified intra-operative high blood loss, unplanned emergencies in operation , and multi-operative teams increases the risk of an unidentified retained foreign object (URFO). Our community hospital's URFO policy was revised to incorporate changes that mandate a “full stop for counts” prior to closure of incision. An initial didactic session was held to educate the staff and residents on the new policy. Three months later a survey indicated a need for improvement in retention. A simulation was then created as an adjunct to didactics to educate on systematic approaches to preventing URFO in the operating room (OR) and utilizing root cause analysis to analyze the simulated sentinel event and highlight the new URFO policy. A survey was subsequently done at the one year interval to measure follow up retention of knowledge. Methods: The “baseline knowledge” and “knowledge retention” was assessed by pre (before simulation) and post (1 year) survey. Education on policy was conducted at the onset and six month interval with simulation incorporated in the latter. A multi-disciplinary team including residents, OR and anesthesia staff, designed and simulated a scenario with an emergency operation that is susceptible to URFO error. The Patient Safety Officer (PSO) gave a report that 5 days after abdominal closure a retained sponge was found on abdominal x-ray. A root cause analysis was then performed allowing the residents to verify the role of our new URFO policy on preventing such events (Figure 1). Results: Using a survey (n=62), the majority of trainees improved in recognizing crew resource management as the primary way of preventing a sentinel event during a simulation at one year follow-up (78.6% to 98.4%) (Figure 2). Retention had improved, with 91.3% correctly indicated that standardized method (debrief, closed loop, sponge counting) were a better check than varying practices for preventing URFOs. The trainees correctly indicated (93.5%) from baseline of 75% that “finding the individual responsible for the mistake” was not the goal, and 91.9% correctly identified the primary focus of the root cause analysis of this scenario was failure in “system design.” However only 71% of trainees at one year indicated confidence in their understanding of the URFO policy and could assist others in performing URFO-related roles. Conclusions: Simulation can be integrated into the residency curriculum as an adjunct to increase retention in teaching safety policy. The trainees were given the opportunity to learn the concept of root cause analysis and identify factors that lead to URFO. Simulation is a methodology that needs to be explored further to develop a framework for a patient safety curriculum in graduate medical education. (Figure Presented). AD - B. Ionescu AU - Ionescu, B. AU - Young, N. AU - Patterson, D. AU - Grim, R. AU - Bell, T. AU - Ahuja, V. DB - Embase IS - 4 KW - follow up gastrointestinal disease simulation policy human student root cause analysis patient safety sentinel event curriculum methodology safety teaching operating room resource management emergency incision emergency surgery error education medical education community hospital risk graduate bleeding anesthesia abdominal radiography LA - English M3 - Conference Abstract N1 - L72273082 2016-05-31 PY - 2016 SN - 0016-5085 SP - S1186 ST - Simulation as an adjunct to didactics to increase knowledge retention: One year follow-up T2 - Gastroenterology TI - Simulation as an adjunct to didactics to increase knowledge retention: One year follow-up UR - https://www.embase.com/search/results?subaction=viewrecord&id=L72273082&from=export VL - 150 ID - 410 ER - TY - JOUR AB - Background Despite improvement in operative techniques and antibiotic therapy, septic complications still occur in open fractures. We developed silver ion containing ceramic nano powder for implant coating to provide not only biocompatibility but also antibacterial activity to the orthopaedic implants. Questions/purposes We hypothesised silver ion doped calcium phosphate based ceramic nano-powder coated titanium nails may prevents bacterial colonisation and infection in open fractures as compared with uncoated nails. Methods 33 rabbits divided into three groups. In the first group uncoated, in the second group hydroxyapatite coated, and in the third group silver doped hydroxyapatite coated titanium nails were inserted left femurs of animals from knee regions with retrograde fashion. Before implantation of nails 50 μl solution containing 106 CFU/ml methicillin resistance Staphylococcus aureus (MRSA) injected intramedullary canal. Rabbits were monitored for 10 weeks. Blood was taken from rabbits before surgery and on 2nd, 6th and 10th weeks. Blood was analysed for biochemical parameters, blood count, C-reactive protein and silver levels. At the end of the 10 weeks animals were sacrificed and rods were extracted in a sterile fashion. Swab cultures were taken from intramedullary canal. Bacteria on titanium rods were counted. Liver, heart, spleen, kidney and central nervous tissues samples were taken for determining silver levels. Histopathological evaluation of bone surrounding implants was also performed. Results No significant difference was detected between the groups from hematologic, biochemical, and toxicological aspect. Microbiological results showed that less bacterial growth was detected with the use of silver doped ceramic coated implants compared to the other two groups (p = 0.003). Accumulation of silver was not detected. No cellular inflammation was observed around the silver coated prostheses. No toxic effect of silver on bone cells was seen. Conclusion Silver ion doped calcium phosphate based ceramic nano powder coating to orthopaedic implants may prevents bacterial colonisation and infection in open fractures compared with those for implants without any coating. © 2015 Elsevier Ltd. All rights reserved. AD - Eskisehir Osmangazi University, Medical Faculty, Department of Orthopedics and Traumatology, Meselik, Eskisehir, 26480, Turkey Anadolu University, Department of Materials Science and Engineering, Eskisehir, Turkey Eskisehir Osmangazi University, Medical Faculty, Department of Microbiology, Eskisehir, Turkey Eskisehir Osmangazi University, Medical Faculty, Department of Histology, Eskisehir, Turkey Anadolu University, Department of Enviromental Engineering, Eskisehir, Turkey AU - Kose, N. AU - Çaylak, R. AU - Pekşen, C. AU - Kiremitçi, A. AU - Burukoglu, D. AU - Koparal, S. AU - Doʇan, A. DB - Scopus DO - 10.1016/j.injury.2015.10.006 IS - 2 KW - Bacterial colonisation Calcium phosphate ceramic Silver ion M3 - Article N1 - Cited By :27 Export Date: 10 November 2020 PY - 2016 SP - 320-324 ST - Silver ion doped ceramic nano-powder coated nails prevent infection in open fractures: In vivo study T2 - Injury TI - Silver ion doped ceramic nano-powder coated nails prevent infection in open fractures: In vivo study UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84962596983&doi=10.1016%2fj.injury.2015.10.006&partnerID=40&md5=ee0e7225a11b075102bbd78230c7f00d VL - 47 ID - 1194 ER - TY - JOUR AB - The information reported at this symposium presents initial data supporting the notion that patients with exposure to silicone gel are experiencing a new illness. Previously, this disorder was described variously as "human adjuvant disease" and chronic silicone arthropathy.15 During the symposium, the term siliconosis and silicone implant syndrome (SIMS) was used to describe the clinical syndrome associated with patients receiving silicone gel in liquid or encapsulated form. I prefer the term siliconosis because it is inclusive of symptomatic women who were exposed to silicone gel by injection or implant placement. Siliconosis is characterized by a spectrum of illness that may affect a number of organs. In its most common form, siliconosis is a musculoskeletal pain syndrome characterized by overwhelming fatigue, arthralgias, and myalgias. This form of the illness is reminiscent of a chronic flulike state. Influenza patients have overwhelming fatigue, fever, myalgias, and arthalgias. Common laboratory tests, such as complete blood count, erythrocyte sedimentation rate, and ANA are normal in individuals with influenza. It is difficult to document the presence of the virus, although the disease is diagnosed by physicians in the absence of positive viral cultures. Release of immune mediators (cytokines) by mononuclear cells is the most likely mechanism for the presence of constitutional symptoms. A similar circumstance may occur with the release of cytokines by mononuclear cells ingesting silicone. The criteria for classification of fibromylagia include generalized pain in symmetrical areas of the body including those above and below the waist.29 Also included is pain with palpation in 11 of 18 tender point sites. Other factors associated with fibromylagia include nonrestorative sleep, daytime fatigue, chronic headache, and irritable bowel syndrome. Criteria for chronic fatigue syndrome include persistent fatigue sufficient to reduce daily activity by 50% or more for a period over 6 months, along with chills, cervical lymphadenopathy, headaches, myalgias, sleep disturbance, and fever.30 Patients with silicone breast implants have similar but not identical symptoms associated with these other disorders. The severity of fatigue and the presence of a limited number of tender points differentiates this illness from fibromyalgia and chronic fatigue syndrome. Patients with fibromyalgia associated with siliconosis do not have symmetrical tender points. Most tender points are located above the waist, and < 11 are identified in these patients. Siliconosis also differs from chronic fatigue syndrome. Patients with breast implants do not have fever, which is a frequent manifestation of chronic fatigue syndrome. Laboratory tests are normal in chronic fatigue syndrome, whereas a third of symptomatic patients with silicone breast implants have abnormal laboratory tests including ANAs. In addition to the musculoskeletal symptoms associated with siliconosis, a minority of patients also experience skin rash, alopecia, fever, lymphadenopathy, and arthritis. A significant number of patients develop a Sjögren's-like disorder characterized by xerophthalmia and xerostomia. However, there is an absence of autoantibodies and cellular infiltrates associated with classic Sjögren's syndrome. Systemic lupuslike syndrome may appear with arthralgias, skin rash, and fever in the absence of detectable ANA. Rheumatoid arthritis-like disease may be characterized by years of polyarthritis without significant erosions or periarticular osteopenia. Neurological symptoms in the form of shortterm memory loss, paresthesias, and neuropathy have been reported.31. The pathogenesis of this disorder remains to be determined. The report of Kossovsky suggests that the alterations in plasma proteins facilitate the ingestion of silicone by macrophages that initiate an immunological response characterized by a chronic inflammatory state that is associated with the production of autoantibody and cytokines. The capsule surrounding implants is a potential site for pro uction of a number of immunologically active factors that could result in patient symptoms. Inflammatory reaction, including lymphocytes, monocytes, and plasma cells, has been identified in implant patients, with or without overt leakage.32 Increased amounts of interleukin 2 have been detected in capsules surrounding breast implants.33 The presence of these factors may explain the reason for the presence of the syndrome in patients with intact implants. Clinical symptoms associated with this pathological immunological state may occur in genetically predisposed patients. Preliminary studies suggest that genetically predisposed patients may have the DR53 haplotype.34. Patients whose implants were removed have reported improvement in symptoms. The improvement is not immediate in most patients. Some patients report improvement that has its onset 12 months or more after explantation. This time course of improvement does not follow a course expected with placebo effect. One would predict that improvement with explantation would be immediate with placebo effect. Explantation of the implants, along with the surrounding capsule, removes a large amount of silicone from the patient. Improvement over 12 months or longer suggests that an abnormal immune response is decreasing with removal of the silicone. The amount of silicone that remains in patients with enlarged axillary lymph nodes may not be adequate, over time, to sustain the abnormal immune response. In some patients, the residual amounts of silicone may be adequate to sustain the pathological process. This group may contain the third of patients who do not improve with explantation. Finally, the current controversy involving silicone breast implants seems reminiscent of the debate surrounding the original patients with Lyme disease. The physicians who saw these first patients preferred to diagnose juvenile rheumatoid arthritis, a disease that they knew. Superficially, the illness seemed to be juvenile rheumatoid arthritis because it occurred in children and caused arthritis. However, closer scrutiny revealed that the illness occurred in clusters and affected adults as well as children. The illness was not juvenile rheumatoid arthritis, but a new illness caused by Borrelia burgdorferi and transmitted by a tick (Ixodes dammini). Our current understanding of silicone breast implants is that silicone is not inert and has the capability of causing systemic tissue damage. The mechanism by which this agent results in a clinical disease that differs from other rheumatic disorders remains to be determined. The participants of this symposium hope that the data presented will heighten interest in this condition and result in additional studies to further define the disease and improve therapies for women who are symptomatic from silicone breast implants. © 1994. AU - Borenstein, D. DB - Scopus DO - 10.1016/0049-0172(94)90102-3 IS - 1 SUPPL. 1 M3 - Article N1 - Cited By :64 Export Date: 10 November 2020 PY - 1994 SP - 1-7 ST - Siliconosis: A spectrum of illness T2 - Seminars in Arthritis and Rheumatism TI - Siliconosis: A spectrum of illness UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027934088&doi=10.1016%2f0049-0172%2894%2990102-3&partnerID=40&md5=d44afd16af926b314501aa68496b1179 VL - 24 ID - 1728 ER - TY - JOUR AB - SPLENIC sequestration of blood cells has been identified by several investigators as one cause of pancytopenia in dialyzed patients.1,2 In the case described below, a foreign-body reaction to silicone in the spleen was identified as a cause of pancytopenia, which responded to splenectomy. Case Report The patient was a woman born in 1920, who had polycystic kidneys. In February 1971, her serum creatinine was 9.1 mg per deciliter, her hemoglobin was 12.8 g per deciliter, her leukocyte count was 6500 per microliter, and her platelet count was 204,000 per microliter. Since November 1971, she has been receiving maintenance hemodialysis —. © 1981, Massachusetts Medical Society. All rights reserved. AD - Departments of Internal Medicine, Departments of Pathology, Ruperto-Carola-University Heidelberg, Heidelberg, Germany AU - Bommer, J. AU - Ritz, E. AU - Waldherr, R. DB - Scopus DO - 10.1056/NEJM198110293051809 IS - 18 M3 - Article N1 - Cited By :41 Export Date: 10 November 2020 PY - 1981 SP - 1077-1079 ST - Silicone-Induced Splenomegaly: Treatment of Pancytopenia by Splenectomy in a Patient on Hemodialysis T2 - New England Journal of Medicine TI - Silicone-Induced Splenomegaly: Treatment of Pancytopenia by Splenectomy in a Patient on Hemodialysis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019837851&doi=10.1056%2fNEJM198110293051809&partnerID=40&md5=c60e5189c82f4ef04df2bb14663192e3 VL - 305 ID - 1764 ER - TY - JOUR AB - Migration of ventriculoperitoneal shunt catheters, although infrequent, is well reported. We report the unusual event of a patient who, after having had three shunt revisions over a 15-year period, presented with a per-oral extrusion of her original distal catheter. Crown Copyright © 2009. AD - Neurosurgery, St Vincent's Hospital, 406 Victoria Street, Darlinghurst, NSW 2010, Australia AU - Sinnadurai, M. AU - Winder, M. J. DB - Scopus DO - 10.1016/j.jocn.2008.12.029 IS - 10 KW - Migration Shunt Transoral Ventriculoperitoneal M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2009 SP - 1348-1350 ST - Silicone spaghetti T2 - Journal of Clinical Neuroscience TI - Silicone spaghetti UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-68949098416&doi=10.1016%2fj.jocn.2008.12.029&partnerID=40&md5=c4ffba26489a19bbd381b17797da033b VL - 16 ID - 1486 ER - TY - JOUR AD - Department of Dermatology, Henry Ford Health System, 3031 W. Grand Blvd, Detroit, MI 48202, United States Department of Dermatology, School of Medicine, Wayne State University, Detroit, MI, United States AU - Lopiccolo, M. C. AU - Workman, B. J. AU - Chaffins, M. L. AU - Kerr, H. A. DB - Scopus DO - 10.1111/j.1524-4725.2011.01978.x IS - 5 M3 - Article N1 - Cited By :24 Export Date: 10 November 2020 PY - 2011 SP - 720-725 ST - Silicone granulomas after soft-tissue augmentation of the buttocks: A case report and review of management T2 - Dermatologic Surgery TI - Silicone granulomas after soft-tissue augmentation of the buttocks: A case report and review of management UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79955404845&doi=10.1111%2fj.1524-4725.2011.01978.x&partnerID=40&md5=dd1d22b70e59436b6b29f8ac78c0ebf2 VL - 37 ID - 1421 ER - TY - JOUR AB - Background: A 50-year-old lady presented with a 5-month history of persistent left wrist pain and swelling. She was known to have degenerative cystic changes in the base of the thumb metacarpal and had had a left thumb carpometacarpal joint arthroplasty and resection of the trapezium with insertion of a Swanson Silastic implant 4 years previously in 2008. Her past medical history included ovarian carcinoma 7 years ago. For her wrist pain, she was taking naproxen and paracetamol which helped provide some pain relief. Her niece has RA. She was a 30-pack year smoker and drank a minimal amount of alcohol. She worked in a warehouse, which involved heavy manual work. Examination revealed left wrist synovitis with reduced range of movement. She also had some tenderness around the left 3rd and 4th PIPJ. In comparison, examination of her right wrist was normal. Examination of her nails, skin, and other joints was unremarkable. Her cardiorespiratory and abdominal examinations were also unremarkable. Methods: Initial investigations including rheumatoid factor, anti-CCP, ANA and inflammatory markers and radiographs of the hands and wrists were performed. Further investigations included a MRI of the left wrist and a synovial biopsy. Results: Blood tests revealed a negative rheumatoid factor and ANA, and her anti-CCP was normal. Her ESR 17, CRP<5 and normal full blood count, renal and liver function. A radiograph of the left wrist showed a previous left trapeziectomy with a silastic prosthetic replacement. There was evidence of a considerable erosive process affecting her carpometacarpal, carpal and radiocarpal joints of the left wrist. This suggested that the arthropathy was crossing ligamentous boundaries. Fracture was excluded. A MRI scan of her left wrist (with gadolinium) was performed and confirmed the presence of an erosive process and a suggestion of fragmentation of the implant. A synovial biopsy was then taken. Histopathology of the left wrist synovium revealed multiple pale grey fragments together measuring 0.7x0.7x0.3 cm. Microscopy showed a florid giant cell reaction to refractile, granular material. The appearances were consistent with previous surgery at this site with a giant cell reaction to foreign material. The acid-fast bacilli culture was negative. Conclusions: This patient's wrist pain was due to a giant cell synovitis secondary to particulate silastic from a previous silastic implant. Silastic synovitis can occur at any joint where there is a prosthetic implant in place. Involvement of the hand and wrist is however most common at the carpal bones which are more susceptible to stress forces. An inflammatory process occurs in response to foreign particles, which are sloughed off the implant, resulting in erosion of bone and articular cartilage with intraosseous cystic changes. Histopathology reveals an inflammatory infiltrate with giant cells around silicone-elastomer particles. A review of the literature will also be presented. AD - R. Seth, Rheumatology Department, Queen Alexandra Hospital, Portsmouth, United Kingdom AU - Seth, R. AU - McCrae, F. DB - Embase DO - 10.1093/rheumatology/ket197 KW - silastic rheumatoid factor alcohol paracetamol naproxen gadolinium marker alprazolam rheumatology society synovitis health practitioner human wrist examination giant cell wrist pain X ray film surgery silicone prosthesis thumb joint biopsy histopathology foreign body implant ovary carcinoma skin arthroplasty swelling nuclear magnetic resonance imaging carpal bone analgesia manual labor synovium arthropathy blood cell count blood liver function prosthesiology fracture microscopy acid fast bacterium patient endoprosthesis inflammation bone articular cartilage inflammatory infiltrate medical history carpometacarpal joint smoking LA - English M3 - Conference Abstract N1 - L71070806 2013-06-04 PY - 2013 SN - 1462-0324 SP - i57 ST - Silastic synovitis: A case and review of the literature T2 - Rheumatology (United Kingdom) TI - Silastic synovitis: A case and review of the literature UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71070806&from=export http://dx.doi.org/10.1093/rheumatology/ket197 VL - 52 ID - 485 ER - TY - JOUR AD - Department of Surgery A, Galilee Medical Center, Nahariya, Israel Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel AU - Kakiashvili, E. AU - Mansour, M. AU - Weiss, M. AU - Barhoum, M. AU - Khatib, K. AU - Bickel, A. DB - Scopus IS - 4 KW - Emergency surgery Laparotomy Retained foreign body Syrian civil war Wartime casualty M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2018 SP - 211-212 ST - The significance of routine computer tomography in evaluation of asymptomatic postoperative war trauma patients transferred from Syria for further treatment T2 - Israel Medical Association Journal TI - The significance of routine computer tomography in evaluation of asymptomatic postoperative war trauma patients transferred from Syria for further treatment UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85045507188&partnerID=40&md5=b997e4a0cc11307f5b8dd1f9d217afc0 VL - 20 ID - 1082 ER - TY - JOUR AB - Jujube is a common fruit in Chinese diet, jujube pit is sharp but has rarely been reported to cause digestive tract perforation. Here we presented a rare case of sigmoid colon perforation by a jujube pit in an 88 year-old toothless woman. The evidence of peritoneal irritation was acquired by physical examination and CT scan. Then perforation peritonitis was diagnosed, and emergency operation was performed accordingly. The patient recovered smoothly and was discharged after 10 days of hospital stay. © 2017, Scientific Publishers of India. All rights reserved. AD - Department of Gastrointestinal Surgery, Affiliated Hospital of Putian University, China AU - Chen, J. AU - Lin, W. DB - Scopus IS - 8 KW - Foreign body Jujube Perforation Peritonitis M3 - Article N1 - Export Date: 10 November 2020 PY - 2017 SP - 3583-3584 ST - Sigmoid colon perforation due to a jujube pit T2 - Biomedical Research (India) TI - Sigmoid colon perforation due to a jujube pit UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019545712&partnerID=40&md5=192f5602d15799f58586841257b04783 VL - 28 ID - 1159 ER - TY - JOUR AD - Department of General and Digestive Surgery, Hospital Universitario 12 de Octubre, Madrid, Spain Department of Digestive Diseases, Hospital Universitario 12 de Octubre, Madrid, Spain AU - Alonso-Gómez, S. AU - Rubio-González, E. AU - Donat-Garrido, M. AU - Lomas-Espadas, M. AU - Solís-Herruzo, J. A. AU - Moreno-González, E. DB - Scopus DO - 10.4321/S1130-01082012000200008 IS - 2 M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2012 SP - 90-91 ST - Sigmoid colon perforation due to a foreign body ingestion T2 - Revista Espanola de Enfermedades Digestivas TI - Sigmoid colon perforation due to a foreign body ingestion UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84857769201&doi=10.4321%2fS1130-01082012000200008&partnerID=40&md5=764aeb498687db0b965228f46ff48488 VL - 104 ID - 1388 ER - TY - JOUR AD - Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Chonbuk National University, Jeonju, South Korea Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk, National University Hospital, Jeonju, South Korea AU - Kim, J. S. AU - Kwon, S. H. AU - Lee, E. J. DB - Scopus DO - 10.1177/0145561318823645 IS - 2 M3 - Article N1 - Export Date: 10 November 2020 PY - 2020 SP - 109-110 ST - Shiny Foreign Body in the Frontal Sinus Causing Epidural Abscess T2 - Ear, Nose and Throat Journal TI - Shiny Foreign Body in the Frontal Sinus Causing Epidural Abscess UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85081926042&doi=10.1177%2f0145561318823645&partnerID=40&md5=d74fac120cef27987fcf422acdd9db58 VL - 99 ID - 974 ER - TY - JOUR AD - Private Practice, Sacramento, CA, United States AU - Barad, S. J. DB - Scopus DO - 10.1016/j.jse.2019.02.019 IS - 6 KW - acute bursitis Bio-inductive implant foreign body reaction rice body rotator cuff tear subacromial-subdeltoid bursa M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2019 SP - e190-e192 ST - Severe subacromial-subdeltoid inflammation with rice bodies associated with implantation of a bio-inductive collagen scaffold after rotator cuff repair T2 - Journal of Shoulder and Elbow Surgery TI - Severe subacromial-subdeltoid inflammation with rice bodies associated with implantation of a bio-inductive collagen scaffold after rotator cuff repair UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064258363&doi=10.1016%2fj.jse.2019.02.019&partnerID=40&md5=e00dca2b2419df14128f1be81fc9b5c3 VL - 28 ID - 1007 ER - TY - JOUR AB - Introduction: Pulmonary hemorrhage is a condition with high morbidity that can occur as a result of multiple causes; including pulmonary vasculitis, drug toxicity, aspiration of blood, thrombocytopenia, stem-cell transplant, or sepsis. In many cases no definitive cause is identified. Here, we present an unusual pediatric case of severe pulmonary hemorrhage and respiratory failure with group A streptococcus (GAS) septicemia requiring extracorporeal membrane oxygenation (ECMO). To date, there are few case reports that describe pulmonary hemorrhage in the setting of GAS sepsis. In most published reports, patients presented with a typical prodrome of fever and sore throat that was followed by pulmonary hemorrhage and death. To our knowledge, this is the only report of a patient with pulmonary hemorrhage associated with GAS sepsis that progressed to severe hypoxemic respiratory failure requiring veno-arterial ECMO. A 5-year old boy with a history of mild-persistent asthma presented to a local emergency department with acute onset of inspiratory stridor that rapidly progressed to respiratory failure. History was not concerning for infectious symptoms, foreign body ingestion, or an anaphylactic reaction. Direct laryngoscopy revealed significant airway and vocal cord edema. Initial chest x-ray was unremarkable. The child was stable on minimal ventilatory and oxygen support, and transferred to a tertiary care facility. Nasopharyngeal PCR identified parainfluenza. Dexamethasone was administered for laryngotracheobronchitis and he was observed on positive pressure ventilation overnight. 12 hours later, he developed an episode of acute hypoxemia associated with pulmonary hemorrhage requiring high frequency oscillatory ventilation. Chest x-ray demonstrated bilateral infiltrates. He developed new leukopenia and neutropenia (white blood cell 2200, absolute neutrophil count 830) presumably due to sepsis and he was started on vancomycin and ceftriaxone. Clotting times, fibrinogen, and platelet counts were not consistent with disseminated intravascular coagulopathy. There was no laboratory evidence of autoimmune disease and vasculitis. The following day, he developed hypotension with cardiovascular dysfunction requiring a continuous infusion of epinephrine. Blood and endotracheal cultures grew GAS, and clindamycin was added for anti-toxin effects. His oxygenation continued to deteriorate (oxygenation index mid 40's, PaO2/FiO2 ratio of <75) despite a mean airway pressure of 28 cm water pressure, and he was cannulated for veno-arterial ECMO. On ECMO his lungs were recruited with airway positive release ventilation (APRV). There was no further pulmonary hemorrhage and his pulmonary compliance and native gas exchange eventually improved. He was decannulated after 9 days on ECMO and extubated 6 days later. The patient's lack of prodrome and initially negative blood culture on admission suggest that his GAS infection occurred as a superinfection of a primary viral process. V-A ECMO was successfully implemented in this case of GAS sepsis/pneumonitis with pulmonary hemorrhage and cardiorespiratory failure to provide oxygenation and hemodynamic support. AD - A. Khilanani, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States AU - Khilanani, A. AU - Smith, C. DB - Embase DO - 10.1097/01.ccm.0000440439.70087.9f IS - 12 KW - fibrinogen oxygen vancomycin ceftriaxone dexamethasone epinephrine clindamycin toxin water intensive care lung hemorrhage human sepsis hospital patient society respiratory failure oxygenation patient blood airway air conditioning pulmonary vasculitis Streptococcus group A vocal cord laryngoscopy septicemia extracorporeal oxygenation soft contact lens stridor transplantation stem cell thrombocytopenia mild persistent asthma positive pressure ventilation boy emergency ward leukocyte foreign body ingestion anaphylaxis platelet count disseminated intravascular clotting edema vasculitis child tertiary care center Parainfluenza virus infection laryngotracheobronchitis death morbidity sore throat thorax radiography fever aspiration hypoxemia male leukopenia neutropenia neutrophil count blood clotting time blood culture case report laboratory autoimmune disease hypotension continuous infusion airway pressure lung compliance lung gas exchange group A streptococcal infection superinfection cardiopulmonary insufficiency drug toxicity LA - English M3 - Conference Abstract N1 - L71534379 2014-07-22 PY - 2013 SN - 0090-3493 SP - A308 ST - Severe pulmonary hemorrhage in patient with group a streptococcal sepsis requiring ECMO T2 - Critical Care Medicine TI - Severe pulmonary hemorrhage in patient with group a streptococcal sepsis requiring ECMO UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71534379&from=export http://dx.doi.org/10.1097/01.ccm.0000440439.70087.9f VL - 41 ID - 468 ER - TY - JOUR AB - Infections in the neck layers and spaces are potentially life-threatening diseases causing further complications, like mediastinitis, airway obstruction, or sepsis. Despite of the need for a conservative approach, they still regularly require surgical intervention. Records of 17 patients with severe neck infections that were treated by wide external incision and open wound management were retrospectively analyzed. The aim of the study was to clinically characterize these most serious neck infections. The most common presenting symptoms were neck pain and tense neck mass (94-94 %) regularly with fever (65 %), always accompanied by a marked elevation of C reactive protein level (average 192 uG/l). These findings were constant and very similar among both the deep neck infection and necrotizing fasciitis cases. More than half of the patients (53 %) had at least one systemic co-morbidity. The parapharyngeal space was most commonly affected (83 %), but extended disease involving more than two major neck regions was found in 13 cases (76 %). Dental (29 %) was the most common primary infection, followed by peritonsillar abscess (23 %), Microbiological results showed a wide variety of corresponding bacteria. Mediastinitis was developed in three cases (18 %), and airway obstruction requiring tracheostomy in two cases (12 %). All the patients survived. Severe neck infections are a heterogenous group of diseases regarding to the primary site of infection, microbiology, localisation and host reaction. However, rapidly developed, painful, tense neck mass with a highly elevated CRP level should always alert for an extended or phlegmonous process in the layers or spaces of the neck. © 2014, Springer-Verlag Berlin Heidelberg. AD - Department of Otolaryngology and Head and Neck Surgery, Bajcsy-Zsilinszky Hospital, Maglódi Street 89-91, Budapest, 1106, Hungary Department of Otolaryngology and Head and Neck Surgery, County Hospital, Oberwart, Austria Department of Otolaryngology and Head and Neck Surgery, Jahn Ferenc Hospital, Budapest, Hungary AU - Horváth, T. AU - Horváth, B. AU - Varga, Z. AU - Liktor, B., Jr. AU - Szabadka, H. AU - Csákó, L. AU - Liktor, B. DB - Scopus DO - 10.1007/s00405-014-3367-x IS - 11 KW - Deep neck infection External drainage Necrotizing fasciitis Surgery M3 - Article N1 - Cited By :9 Export Date: 10 November 2020 PY - 2015 SP - 3469-3474 ST - Severe neck infections that require wide external drainage: clinical analysis of 17 consecutive cases T2 - European Archives of Oto-Rhino-Laryngology TI - Severe neck infections that require wide external drainage: clinical analysis of 17 consecutive cases UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84942108642&doi=10.1007%2fs00405-014-3367-x&partnerID=40&md5=c184350bc657f64b6e60981d99746148 VL - 272 ID - 1214 ER - TY - JOUR AB - Introduction.- Transcatheter aortic valve implantation (TAVI) has recently emerged as alternative treatment for symptomatic aortic stenosis in pts at high surgical risk. Two bioprosthesis valves are commonly implanted nowadays, one is the self-expanded valve - Medtronic CoreValve, a valve in porcine pericardium mounted on a nitinol stent. Usually a transient increase of inflammatory indices and mild fever are observed 24-48 h post-TAVI. Results.- A 81-year-old male patient (pt) was admitted to cardiology Department in October 2012 for a planned TAVI with CoreValve. At admission he was afebrile, the chest X-ray showed no lesions, CRP and ANCA were negative. He only presented new slight anemia (Hb 10.3 g/dl) (FOB repeatedly positive, pt on OAT). Since January 2007 pt was seen at the vasculitis clinic because of anti-MPO positive MPA. Pt was treated with steroids and ev cyclophosphamide and then with Methotrexate until February 2010. In May 2010 he started to complain of symptoms that in Nov 2010 were found consistent with Horton arteritis. He resumed steroids and symptoms remitted. At the time of admission, the steroid dosage was 7.5 mg/day. TAVI was uneventful except for a valve in valve procedure due to a “low” valve implantation with a final mild aortic regurgitation. Twelve hours later, pt developed a rash that persisted for 4 days. From day 5, severe increase in CRP with normal procalcitonin values and reduction in plts count (nadir on the day 680,000/μl) were demonstrated. On day 6, pt started to complain of shortness of breath and hemoptysis, and from day 8, of fever. Chest X-ray and CT-scan showed diffuse interstitial-alveolar infiltrates. ANCA were confirmed negative as were anti-GBM, anti-DsDNA, anti-phospholipids. Complement fractions were normal. Sputum cultures were repeatedly negative, as was an extensive work up for infectious conditions. Normal valve position and ventricular function were demonstrated by frequent echocardiographic controls. Pt was treated with steroids and supportive care. Pt continued to cough blood until day 19 and 20, when he was treated with nebulized rFVIIa that stopped bleeding. After a transient improvement of clinical and radiological picture, respiratory conditions deteriorated and on day 32 pt died. Autopsy revealed hyperemic lungs at gross examination, with firm gray-brown or pale edematous areas. Histologically pneumonia organizing aspect was prevalent, associated to rare suppurative foci. Only minimal intra-alveolar blood was observed at the periphery of organizing areas. Both septal and interstitial vessels were dilated and congested. Only focal alveolar or interstitial hemosiderin-laden macrophages were present at Pearls stain. Conclusion.-The clinical spectrum of diffuse alveolar haemorrhage is wider than previously considered. Besides the well-known vasculitic syndromes, immune or hypersensitivity reactions to medications and foreign materials, direct toxic effects to alveolar capillaries, coagulation defects, hemodynamic and vascular conditions, infectious causes should be taken into account. Identification of different causes and treatment based on the different etiologies are challenging tasks. AD - G.A. Gregorini, Spedali Civili Di Brescia, UO Nefrologia e Dialisi, Brescia, Italy AU - Gregorini, G. A. AU - Fiorina, C. AU - Bonetti, M. F. DB - Embase DO - 10.1016/j.lpm.2013.02.270 IS - 4 KW - steroid methotrexate cyclophosphamide procalcitonin phospholipid hemosiderin temporal arteritis human hospital patient lung hemorrhage remission allergic reaction vasculitis workshop transcatheter aortic valve implantation thorax radiography blood fever computer assisted tomography patient male rash dyspnea cardiology nitinol stent procedures pericardium bioprosthesis arteritis implantation aortic regurgitation macrophage hemoptysis surgical risk pneumonia aortic stenosis lung hospital autopsy bleeding examination coughing heart ventricle function sputum culture stain drug therapy foreign body toxicity capillary blood clotting disorder etiology anemia LA - English M3 - Conference Abstract N1 - L71944007 2015-07-21 PY - 2013 SN - 0755-4982 SP - 765-766 ST - Severe diffuse alveolar haemorrhage after TAVI with CoreValve in patient with AAV and Horton disease in remission. An immuno-allergic reaction? T2 - Presse Medicale TI - Severe diffuse alveolar haemorrhage after TAVI with CoreValve in patient with AAV and Horton disease in remission. An immuno-allergic reaction? UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71944007&from=export http://dx.doi.org/10.1016/j.lpm.2013.02.270 VL - 42 ID - 486 ER - TY - JOUR AB - This is the second paper that presents the results of research about the role and effectiveness of ACORN. The first paper, published in the last edition of the ACORN journal [1], presented the data about the role of ACORN, which demonstrated the significance of the ACORN standards. The majority of respondents, who were perioperative nurse managers and former or current ACORN Board members, believed the standards had a positive effect on nursing practice and patient outcomes, and were the benchmark for perioperative nursing practice. Although most respondents professed the value of the standards, occasionally their beliefs were tempered by a number of other issues that emerged from the data about standards. The opinions of a minority of respondents contrasted with the beliefs of most of them; however, these 'minority' opinions were revealing, too.This paper focuses on the results of analysis of the data collected about the ACORN counting standard [2]. These were in Part E of the NUM questionnaire (NUM Q) [3]. This part sought to ascertain if the ACORN counting standard was used to inform counting practices in the respondents' operating suites, and if respondents believed it prevented the inadvertent retention of a surgical item. Also elicited was information on how respondents reported and dealt with cases of incorrect counts and missing surgical items. AD - Lecturer, University of Technology, Sydney (UTS), Sydney, NSW, Australia AN - 106336077. Language: English. Entry Date: 20060922. Revision Date: 20150820. Publication Type: Journal Article AU - Hamlin, L. DA - 2006 Winter DB - ccm DP - EBSCOhost IS - 2 KW - Australian College of Operating Room Nurses Perioperative Nursing Surgical Count Procedure Australian College of Operating Room Nurses -- Standards Descriptive Research Descriptive Statistics Incident Reports Needles Private Sector Public Sector Questionnaires Record Review Retained Instruments RN Mix Surgical Sponges Human N1 - research; tables/charts. Journal Subset: Australia & New Zealand; Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. Instrumentation: NUM Q. PY - 2006 SN - 1448-7535 SP - 24-29 ST - Setting the standard: the role of ACORN. Part II: counting, the gold standard to prevent the inadvertent retention of surgical items -- or is it? T2 - ACORN: The Journal of Perioperative Nursing in Australia TI - Setting the standard: the role of ACORN. Part II: counting, the gold standard to prevent the inadvertent retention of surgical items -- or is it? UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106336077&site=ehost-live&scope=site VL - 19 ID - 847 ER - TY - JOUR AB - After surgery, the most common foreign bodies retained in the abdominal cavity are the surgical sponges. The aim of the present study was to emphasize the importance of gossypiboma, which is a serious and medicolegal problem. The records of 12 patients with a confirmed diagnosis of gossypiboma after abdominal surgery at Dicle University Hospital were retrospectively reviewed between January 1994 and December 2009. Eight of the 12 patients were females, and 4 were males. Previously, 7 patients had been operated on electively, and 5 had undergone operations on an emergency basis. Abdominal ultrasonography clearly demonstrated gossypibomas in 5 patients, and computed tomography demonstrated a more precise image of retained surgical sponges in 3 patients. One patient died because of ventricular fibrillation; the other 11 patients were discharged in good health. To eliminate the risk of gossypibomas, all sponges should be counted at least twice (once preoperatively and once postoperatively); use of small sponges should be avoided during laparotomy, and only sponges with radiopaque markers should be used. The surgeon should explore the abdomen before closure. In cases in which the sponge count is uncertain, an abdominal x-ray should be performed before closure. AD - Department of General Surgery, Medical Faculty, Dicle University, Diyarbakir, Turkey. metehangumus@yahoo.com AN - 21562399 AU - Gümüş, M. AU - Gümüş, H. AU - Kapan, M. AU - Onder, A. AU - Tekbaş, G. AU - Baç, B. DA - Mar DO - 10.1097/PAF.0b013e31821c09fe DP - NLM ET - 2011/05/13 IS - 1 KW - Adult Aged Female Foreign Bodies/*diagnosis/prevention & control Humans Male *Medical Errors Middle Aged Radiography, Abdominal Retrospective Studies Surgical Procedures, Operative Surgical Sponges/*adverse effects Tomography, X-Ray Computed Ultrasonography LA - eng N1 - 1533-404x Gümüş, Metehan Gümüş, Hatice Kapan, Murat Onder, Akn Tekbaş, Güven Baç, Bilsel Journal Article United States Am J Forensic Med Pathol. 2012 Mar;33(1):54-7. doi: 10.1097/PAF.0b013e31821c09fe. PY - 2012 SN - 0195-7910 SP - 54-7 ST - A serious medicolegal problem after surgery: gossypiboma T2 - Am J Forensic Med Pathol TI - A serious medicolegal problem after surgery: gossypiboma VL - 33 ID - 108 ER - TY - JOUR AB - Septic pericarditis and myocardial abscess are rare conditions in dogs. They are usually caused by foreign bodies, penetrating wounds, systemic infections or extension of local infections such as endocarditis, pleuritis or pulmonary infections to the myocardial tissue. Here we report a septic pericardial effusion and myocardial abscess in a young English Springer spaniel presenting with a long history of pyrexia and lethargy. No cause could clearly be identified although a penetrating injury or dissolving foreign body was highly suspected. The patient was successfully treated with a surgical approach in combination with broad spectrum antibacterials resulting in resolution of clinical signs without recurrence of the infection. © 2013 Elsevier B.V. All rights reserved. AD - Small Animal Teaching Hospital, School of Veterinary Science, Leahurst Campus, Neston, Cheshire CH64 7TE, United Kingdom Hospital for Small Animal, Royal (Dick) School of Veterinary Studies, Easter Bush Campus, Roslin EH25 9RG, United Kingdom AU - Fraga Veloso, G. AU - Fraga Manteiga, E. AU - Trehy, M. AU - Freeman, A. AU - McConnell, J. F. AU - Dukes McEwan, J. DB - Scopus DO - 10.1016/j.jvc.2013.09.002 IS - 1 KW - Canine Myocarditis Pericardial M3 - Article N1 - Cited By :12 Export Date: 10 November 2020 PY - 2014 SP - 39-44 ST - Septic pericarditis and myocardial abscess in an English Springer spaniel T2 - Journal of Veterinary Cardiology TI - Septic pericarditis and myocardial abscess in an English Springer spaniel UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84896397216&doi=10.1016%2fj.jvc.2013.09.002&partnerID=40&md5=878a621f4e18aee3eafd228fb338f684 VL - 16 ID - 1286 ER - TY - JOUR AB - Cellulosimicrobium cellulans has been reported as a rare cause of human pathogenesis. Infections mainly occur in immunocompromised patients and very often are associated with a foreign body. We report the first case of septic arthritis caused by C. cellulans in an immunocompetent patient. Our patient suffered a penetrating palm tree thorn injury to his left knee 8 weeks before admission. Although no foreign objects were found, they were suspected because previous reports suggest a frequent association with this microorganism, and open debridament was performed. Removal of foreign bodies related to this organism must be considered a high-priority treatment in these patients to achieve a complete recovery. Copyright © 2011, American Society for Microbiology. All Rights Reserved. AD - Department of Rheumatology, Hospital Universitario San Cecilio, Avda. Dr. Olóriz 16, Granada, Spain Department of Infectious Diseases, Hospital Universitario San Cecilio, Granada, Spain Department of Microbiology, Hospital Universitario San Cecilio, Granada, Spain AU - Magro-Checa, C. AU - Chaves-Chaparro, L. AU - Parra-Ruiz, J. AU - Peña-Monje, A. AU - Rosales-Alexander, J. L. AU - Salvatierra, J. AU - Raya, E. DB - Scopus DO - 10.1128/JCM.05058-11 IS - 12 M3 - Article N1 - Cited By :10 Export Date: 10 November 2020 PY - 2011 SP - 4391-4393 ST - Septic arthritis due to cellulosimicrobium cellulans T2 - Journal of Clinical Microbiology TI - Septic arthritis due to cellulosimicrobium cellulans UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-82455220395&doi=10.1128%2fJCM.05058-11&partnerID=40&md5=9d8e3cf5e6663f00870b92e7094c5451 VL - 49 ID - 1399 ER - TY - JOUR AB - Septic arthritis has increased in incidence in the United States in the past two decades, and increasingly affects an older population with a greater burden of chronic illness and a higher risk for drug-resistant organisms. Successful management depends on a high diagnostic suspicion, empiric antibiotic treatment, and joint drainage. A bacteriologic diagnosis is more likely with inoculation into blood culture bottles than plating on solid media. As MRSA increases in prevalence in the community, empiric antibiotic regimens increasingly need to be active against MRSA. © 2005 Elsevier Inc. All rights reserved. AD - Division of Infectious Diseases, Caritas Saint Elizabeth's Medical Center, 736 Cambridge Street, Boston, MA 02135, United States AU - Ross, J. J. DB - Scopus DO - 10.1016/j.idc.2005.07.004 IS - 4 M3 - Review N1 - Cited By :70 Export Date: 10 November 2020 PY - 2005 SP - 799-817 ST - Septic arthritis T2 - Infectious Disease Clinics of North America TI - Septic arthritis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-27744480521&doi=10.1016%2fj.idc.2005.07.004&partnerID=40&md5=ad5d3f9098e15ac2e7ebb2e79f55051a VL - 19 ID - 1596 ER - TY - JOUR AN - 112298081. Language: English. Entry Date: 20160209. Revision Date: 20161213. Publication Type: Article DB - ccm DP - EBSCOhost IS - 12 KW - Sentinel Event Retained Instruments -- Prevention and Control Surgical Count Procedure -- Methods Joint Commission Assistive Technology Education, Continuing (Credit) Documentation Communication N1 - CEU. Note: For CE see www.cmecity.com. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Patient Safety. NLM UID: 7810150. PY - 2013 SN - 0190-5066 SP - 135-136 ST - Sentinel Event Alert issued on retained surgical items T2 - Same-Day Surgery TI - Sentinel Event Alert issued on retained surgical items UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=112298081&site=ehost-live&scope=site VL - 37 ID - 811 ER - TY - JOUR AB - BACKGROUND: A retained surgical sponge is a serious medical error that results in negative patient outcomes. Radiofrequency (RF) technology has recently been introduced to evaluate for the presence of a retained sponge. The aim of this study was to evaluate the sensitivity and specificity of the detection of surgical sponges embedded with an RF chip through the torsos of subjects of varying body habitus, including the morbidly obese. METHODS: A prospective, crossover, and observer blinded study design was used. Subjects served as their own controls. With the subject supine, 4 surgical sponges were sequentially placed behind the subject's torso in locations approximating abdominal quadrants. RESULTS: Two hundred ten subjects were enrolled in the study. Nearly half (n = 101) were morbidly obese. Eight hundred forty readings were taken. There were no false-positive or false-negative readings. The sensitivity and specificity of detection of the RF sponges through the torsos of subjects of varying body habitus were 100%. CONCLUSIONS: The sensitivity and specificity of RF sponge technology are much higher than published reports of surgical counts or published findings of intraoperative radiographs for retained sponges. AD - Department of Veterans Affairs, Veterans Health Administration, Iowa City, IA, USA. victoria-steelman@uiowa.edu AN - 21266216 AU - Steelman, V. M. DA - Feb DO - 10.1016/j.amjsurg.2010.05.001 DP - NLM ET - 2011/01/27 IS - 2 KW - Adult Aged Cross-Over Studies Female Foreign Bodies/*diagnosis/*etiology Humans Male Middle Aged Obesity, Morbid/*complications Prospective Studies *Radio Waves Radiography Sensitivity and Specificity Single-Blind Method Surgical Procedures, Operative/methods *Surgical Sponges LA - eng N1 - 1879-1883 Steelman, Victoria M Controlled Clinical Trial Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. United States Am J Surg. 2011 Feb;201(2):233-7. doi: 10.1016/j.amjsurg.2010.05.001. PY - 2011 SN - 0002-9610 SP - 233-7 ST - Sensitivity of detection of radiofrequency surgical sponges: a prospective, cross-over study T2 - Am J Surg TI - Sensitivity of detection of radiofrequency surgical sponges: a prospective, cross-over study VL - 201 ID - 105 ER - TY - JOUR AB - Introduction: In hepatic resections, there has been a high quality demand. The aim of this systematic study was to investigate whether hemostat device can significantly improve outcome in resecting liver surgery, in particular, in high risk patients. Methods: All consecutive patients (mean age, 60.5 [range, 17-96] years) who underwent hepatic resection (nTotal= 770) were prospectively documented in a computer-based registry at a university hospital (tertiary center) over a time period of 10 years and retrospectively evaluated specifically with regard to the use (-/+) of hemostat device (Tissucol®, n=59 / Tachocomb®, n=202 / combination, n=55) indicated (among others) by drainage volume, inflammatory parameters and rate of specific complications (nValidated=541 [100 %]). Results: Most frequently, (a-)/ typical segmental resections were used: n=192/90 (3-segment resection, n=38 only). 1.) For the assignment of patients to the two different groups (-/+hemostat device), weight loss and type of resection were found as significant factors (trend: ASA, cirrhosis), for the amount of drainage volume, ASA, sex, Karnofsky Performance Scale and also type of resections using independent distributed statistical tests such as (χ2, U test [Mann/Whitney]; H test [Kruskal- Willis]; correlation coefficient by Spearman)- no impact: smoking, diabetes, BMI, ethanol. 2.) Not taking into account these parameters, the use of hemostat device was characterized by an increased drainage volume (negative control < Tissucol=Tachocomb < combination). 3.) Using multifactorial analysis of variance, it was found even under correction by the factors with significant impact elucidated in the single test that the application of hemostat device onto the hepatic resection area resulted unexpectedly rather in an increase than a decrease of the drainage volume but 4.) under accompanying more pronounced increase of the white blood cell count (leucocytosis). 5.) General and specific complications such as postoperative bleeding, biliary fistula and subhepatic abscess were not further lowered in a significant manner using hemostat device. Conclusion: Adequate surgery in the operative management of hepatic resection area cannot further be improved or optimized using hemostat device. In this context, drainage volume may not be considered a sufficient rather an orienting parameter. However, there is an inflammatory response detectable most likely indicated by a(n un-)specific effusion and increase of white blood cell count, which can be interpreted as reactive inflammation to foreign material. AD - M. Petersen AU - Petersen, M. AU - Kropf, S. AU - Steinert, R. AU - Jannasch, O. AU - Venerito, M. AU - Meissner, C. AU - Frank, M. DB - Embase IS - 4 KW - hemostatic agent fibrin glue tachocomb alcohol devices surgery foreign body leukocytosis gastrointestinal disease liver resection human leukocyte count Tertiary (period) parameters inflammation patient computer abscess body weight loss effusion bile duct fistula postoperative hemorrhage analysis of variance diabetes mellitus high risk patient smoking correlation coefficient Karnofsky Performance Status liver cirrhosis university hospital register liver surgery LA - English M3 - Conference Abstract N1 - L71888392 2015-05-23 PY - 2015 SN - 0016-5085 SP - S1181-S1182 ST - Sealing of the hepatic resection area using hemostat device does not result in furtherimproved results of adequate surgery but in induction of a detectable reactiveinflammatory response onto foreign material indicated by an enlarged drainagevolume and leucocytosis T2 - Gastroenterology TI - Sealing of the hepatic resection area using hemostat device does not result in furtherimproved results of adequate surgery but in induction of a detectable reactiveinflammatory response onto foreign material indicated by an enlarged drainagevolume and leucocytosis UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71888392&from=export VL - 148 ID - 435 ER - TY - JOUR AB - 33 consecutive patients (18 arthrosis, 15 rheumatoid arthritis), operated on with total knee arthroplasty and randomized to cemented (18 knees) or cementless fixation (15 knees), were investigated with scintimetry 3, 6, 12, and 24 months postoperatively. Migration was evaluated with simultaneous roentgen stereophotogrammetric (RSA) examinations. the scintimetric activity in the ipsilateral femoral diaphy-sis decreased and the activity in the tibial diaphysis increased during the observation period. Constant and low activity was recorded in front of the femoral component. This region was chosen as a reference. Three months after surgery, high activity was noted under the tibial component in knees with a preoperative varus deformity. After 2 years, the activity had decreased to the same level as in the patients with a valgus deformity. Diagnosis and mode of fixation did not influence the activity. Low postoperative activity was recorded in the tibial metaphyses if no rotatory displacement of the tibial component occurred. © 1992 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. AD - Department of Orthopedics, University Hospital, S-901 85, Umeå, Sweden Department of Nuclear Medicine, University Hospital, S-901 85, Umeå, Sweden AU - Nilsson, K. G. AU - Björnebrink, J. AU - Hietala, S. O. AU - Kärrholm, J. DB - Scopus DO - 10.3109/17453679209154814 IS - 2 M3 - Article N1 - Cited By :10 Export Date: 10 November 2020 PY - 1992 SP - 159-165 ST - Scintimetry after total knee arthroplasty: Prospective 2-year study of 18 cases of arthrosis and 15 cases of theumatoid arthritis T2 - Acta Orthopaedica TI - Scintimetry after total knee arthroplasty: Prospective 2-year study of 18 cases of arthrosis and 15 cases of theumatoid arthritis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026511169&doi=10.3109%2f17453679209154814&partnerID=40&md5=f42b505258fb03cf5887f90523905b1d VL - 63 ID - 1736 ER - TY - JOUR AB - This paper reports the effective treatment of Schistosoma japonicum in a mouse model with long-acting praziquantel (PZQ)-loaded poly(ε-caprolactone) implants. The implants yielded stable, high plasma PZQ concentrations ranging 100-1600. ng/mL during the 40-day investigation period. For assessment of efficacy, the implants were implanted into mice immediately after infection and at 1, 2, 3 and 4. weeks after infection to treat the schistosomes at different developmental stages. All the mice were sacrificed at 6. weeks after infection for worm and egg recovery, worm morphology examination, and histopathological analysis of implantation site tissues. The worm burdens, egg burdens, and numbers of miracidia hatched from the retrieved eggs for all the implant-treated groups (except groups T2-A, T4 and T5) were reduced by 100% when compared with the control group. From groups T2-A, T4 and T5, some schistosome debris was recovered. Eggs were found in only group T5 for which the time between infection and implantation was 4. weeks, which enabled the maturation of juvenile female schistosomes into adult ones that lay eggs. Histopathological observations of implantation tissue showed no evidence of granulomatous foreign-body or lymphoid cell aggregation, demonstrating good biocompatibility of the PZQ implants. These results demonstrate that the long-acting PZQ implants can kill schistosomes at any developmental stages and attenuate/avoid the associated liver damage. © 2011 Elsevier Inc. AD - School of Pharmacy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China Shanghai Veterinary Research Institute, The Chinese Academy of Agricultural Sciences, 518 Ziyue Road, Shanghai 200241, China AU - Cheng, L. AU - Lei, L. AU - Guo, S. AU - Zhu, C. AU - Rong, H. AU - Guo, D. AU - Zhang, L. AU - Jiang, Y. AU - Lin, J. DB - Scopus DO - 10.1016/j.exppara.2011.08.003 IS - 3 KW - Implant Praziquantel Schistosoma japonicum Schistosomiasis Sustained release formulation M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2011 SP - 254-259 ST - Schistosoma japonicum: Treatment of different developmental stages in mice with long-acting praziquantel implants T2 - Experimental Parasitology TI - Schistosoma japonicum: Treatment of different developmental stages in mice with long-acting praziquantel implants UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-80054741474&doi=10.1016%2fj.exppara.2011.08.003&partnerID=40&md5=1fc2022b0b64a81df4cedb97860fb708 VL - 129 ID - 1405 ER - TY - JOUR AB - Intraoperative imaging has immense value for teaching and training surgeons by providing part of a future digital medical record of the patient and supportive evidence of good practice and an open attitude to patient safety. We report a case in which intraoperative video recording of an operation allowed us, after an incorrect count, to confidently assert that there was no equipment left behind in the patient. AD - Cardiothoracic Unit, Great Ormond Street Hospital for Children, London, United Kingdom. ahoschtitzky@yahoo.com AN - 19231429 AU - Hoschtitzky, J. A. AU - Trivedi, D. B. AU - Elliott, M. J. DA - Mar DO - 10.1016/j.athoracsur.2008.07.111 DP - NLM ET - 2009/02/24 IS - 3 KW - Cardiac Surgical Procedures/instrumentation Female Foreign Bodies/*diagnosis Heart Septal Defects, Atrial/*surgery Humans Infant *Surgical Instruments *Video Recording LA - eng N1 - 1552-6259 Hoschtitzky, Johann Andreas Trivedi, Dipesh B Elliott, Martin J Case Reports Journal Article Netherlands Ann Thorac Surg. 2009 Mar;87(3):940-1. doi: 10.1016/j.athoracsur.2008.07.111. PY - 2009 SN - 0003-4975 SP - 940-1 ST - Saved by the video: added value of recording surgical procedures on video T2 - Ann Thorac Surg TI - Saved by the video: added value of recording surgical procedures on video VL - 87 ID - 88 ER - TY - JOUR AN - 105054996. Language: English. Entry Date: 20100813. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 7 KW - Information Resources Intraoperative Care -- Standards Intrapartum Care -- Standards Patient Safety Practice Guidelines Surgical Count Procedure World Wide Web N1 - brief item. Journal Subset: Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 9814759. PY - 2010 SN - 1461-3123 SP - 6-6 ST - Safety agency issues vaginal swab guidelines T2 - Practising Midwife TI - Safety agency issues vaginal swab guidelines UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105054996&site=ehost-live&scope=site VL - 13 ID - 925 ER - TY - JOUR AB - Research from the United States which explores events related to the surgical count has identified that there are opportunities to review our practice in order to reduce risks to surgical patients. The Safe Surgery Saves Lives Campaign highlights this aspect of perioperative patient safety, ensuring that poor processes and poor communication, often the reasons for retained surgical items, become part of the team 'sign-out' at the end of every operation. AD - KMW (Healthcare Consultants) Ltd. woodhead8@btinternet.com AN - 19908676 AU - Woodhead, K. DA - Oct DO - 10.1177/175045890901901010 DP - NLM ET - 2009/11/17 IS - 10 KW - Checklist Humans Medical Errors/*prevention & control Risk Management *Safety Management United Kingdom United States LA - eng N1 - Woodhead, Kate Journal Article England J Perioper Pract. 2009 Oct;19(10):358-61. doi: 10.1177/175045890901901010. PY - 2009 SN - 1750-4589 (Print) 1750-4589 SP - 358-61 ST - Safe surgery: reducing the risk of retained items T2 - J Perioper Pract TI - Safe surgery: reducing the risk of retained items VL - 19 ID - 95 ER - TY - JOUR AB - We report a unique case of a ruptured iliac artery pseudoaneurysm caused by asymptomatic gastrointestinal perforation and retroperitoneal abscess formation. A 46-year-old man presented to the Emergency Department of our institution. Angiography showed a ruptured iliac artery pseudoaneurysm caused by retroperitoneal abscess formation. After endovascular repair and surgical drainage, the cause of the abscess was finally identified as a toothpick. Findings from this case show that asymptomatic gastrointestinal foreign body perforation can be a rare, but insidious, cause of an infected pseudoaneurysm. Prompt surgical intervention is sometimes necessary when treating patients with arterial pseudoaneurysm caused by a perivascular abscess. © The Author(s) 2020. AD - Department of Vascular Surgery, The First Hospital, China Medical University, Shenyang, China AU - Lun, Y. AU - Jiang, H. AU - Xin, S. AU - Zhang, J. DB - Scopus DO - 10.1177/0300060520942082 IS - 7 KW - abscess foreign body gastrointestinal infection perforation Pseudoaneurysm M3 - Article N1 - Export Date: 10 November 2020 PY - 2020 ST - Rupture of an infected iliac artery pseudoaneurysm caused by asymptomatic gastrointestinal foreign body perforation T2 - Journal of International Medical Research TI - Rupture of an infected iliac artery pseudoaneurysm caused by asymptomatic gastrointestinal foreign body perforation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85088433713&doi=10.1177%2f0300060520942082&partnerID=40&md5=a1427d1b9222d470b7ffad9349867f1c VL - 48 ID - 980 ER - TY - JOUR AB - Background and purpose - Biological patches can be used to augment rotator cuff tendon repair in an attempt to improve healing and reduce rates of re-rupture. However, little is known about the in vivo tissue response to these patches. We assessed native rotator cuff tissue response after surgical repair and augmentation with 2 commercially available extracellular matrix (ECM) patches.Patients and methods - Patients underwent a rotator cuff repair augmented with either GraftJacket (Wright Medical), Permacol (Zimmer Biomet), or no patch (Control), applied using an onlay technique. A sample of supraspinatus tendon was collected intraoperatively and 4 weeks post-surgery, using ultrasound-guided biopsy. Histology and immunohistochemistry were performed on all samples.Results - The Permacol group (n = 3) and GraftJacket group (n = 4) demonstrated some changes in native tendon ECM compared with the control group (n = 3). Significant disruption of the extracellular matrix of the repaired native supraspinatus, underlying both patches, was observed. The patches did not generally increase cellularity, foreign body giant cell count, or vascularity compared to the control group. 1 patient in the Permacol group had an adverse tissue immune response characterized by extensive infiltration of IRF5(+), CD68(+), and CD206(+) cells, suggesting involvement of macrophages with a pro-inflammatory phenotype. No significant differences in protein expression of CD4, CD45, CD68, CD206, BMP7, IRF5, TGFß, and PDPN were observed among the groups.Interpretation - Histological and immunohistochemical analysis of native tendon tissue after patch augmentation in rotator cuff repair raises some concerns about a lack of benefit and potential for harm from these materials. AD - Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences (NDORMS), Botnar Research Centre, Oxford, UK. AN - 32691656 AU - Rashid, M. S. AU - Smith, R. D. J. AU - Nagra, N. AU - Wheway, K. AU - Watkins, B. AU - Snelling, S. AU - Dakin, S. G. AU - Carr, A. J. DA - Jul 21 DO - 10.1080/17453674.2020.1793613 DP - NLM ET - 2020/07/22 LA - eng N1 - 1745-3682 Rashid, Mustafa S Smith, Richard D J Nagra, Navraj Wheway, Kim Watkins, Bridget Snelling, Sarah Dakin, Stephanie G Carr, Andrew J Journal Article England Acta Orthop. 2020 Jul 21:1-7. doi: 10.1080/17453674.2020.1793613. PY - 2020 SN - 1745-3674 SP - 1-7 ST - Rotator cuff repair with biological graft augmentation causes adverse tissue outcomes T2 - Acta Orthop TI - Rotator cuff repair with biological graft augmentation causes adverse tissue outcomes ID - 257 ER - TY - JOUR AD - Risk Manager, Christiana Care Visiting Nurse Association, New Castle, Delaware Director of Quality/Risk Management, Christiana Care Visiting Nurse Association, New Castle, Delaware AN - 107939750. Language: English. Entry Date: 20131202. Revision Date: 20200708. Publication Type: Journal Article AU - Ewen, Brenda M. AU - Bucher, Gale DB - ccm DO - 10.1097/NHH.0b013e3182aldc32 DP - EBSCOhost IS - 8 KW - Root Cause Analysis Sentinel Event Education, Continuing (Credit) Joint Commission Nomenclature Data Collection Information Resources Incident Reports Female Aged Retained Instruments Surgical Count Procedure Documentation Surgical Sponges Hospital Policies Communication N1 - algorithm; case study; pictorial; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Home Health Care; Patient Safety. NLM UID: 8403379. PY - 2013 SN - 0884-741X SP - 435-443 ST - ROOT CAUSE ANALYSIS T2 - Home Healthcare Nurse TI - ROOT CAUSE ANALYSIS UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107939750&site=ehost-live&scope=site VL - 31 ID - 812 ER - TY - JOUR AB - OBJECTIVE: To prospectively evaluate the ability of radio frequency detection (RFD) system-embedded sponges to mitigate the incidence of retained surgical sponges (RSS) after emergency surgery. BACKGROUND: Emergency surgery patients are at high risk for retained foreign bodies. METHODS: All emergent trauma and nontrauma cavitary operations over a 5-year period (January 2010-December 2014) were prospectively enrolled. For damage-control procedures, only the definitive closure was included. RFD sponges were used exclusively throughout the study period. Before closure, the sponge and instrument count was followed by RFD scanning and x-ray evaluation for retained sponges. RSS and near-misses averted using the RFD system were analyzed. RESULTS: In all, 2051 patients [median (range)], aged 41 (1-101) years, 72.2% male, 46.8% trauma patients, underwent 2148 operations (1824 laparotomy, 100 thoracotomy, 30 sternotomy, and 97 combined). RFD detected retained sponges in 11 (0.5%) patients (81.8%laparotomy, 18.2% sternotomy) before cavitary closure. All postclosure x-rays were negative. No retained sponges were missed by the RFD system. Body mass index was 29 (23-43), estimated blood loss 1.0 L (0-23), and operating room time 160 minutes (71-869). Procedures started after 18:00 to 06:00 hours in 45.5% of the patients. The sponge count was incorrect in 36.4%, not performed due to time constraints in 45.5%, and correct in 18.2%. The additional cost of using RFD-embedded disposables was $0.17 for a 4X18 laparotomy sponge and $0.46 for a 10 pack of 12ply, 4X8. CONCLUSIONS: Emergent surgical procedures are high-risk for retained sponges, even when sponge counts are performed and found to be correct. Implementation of a RFD system was effective in preventing this complication and should be considered for emergent operations in an effort to improve patient safety. AD - Los Angeles County Medical Center and University of Southern California, Division of Trauma Surgery and Surgical Critical Care, Los Angeles, CA. AN - 27433911 AU - Inaba, K. AU - Okoye, O. AU - Aksoy, H. AU - Skiada, D. AU - Ault, G. AU - Sener, S. AU - Lam, L. AU - Benjamin, E. AU - Demetriades, D. DA - Oct DO - 10.1097/sla.0000000000001872 DP - NLM ET - 2016/07/20 IS - 4 KW - Adolescent Adult Aged Aged, 80 and over Child Child, Preschool Female Foreign Bodies/etiology/*prevention & control Humans Infant Laparotomy/adverse effects/instrumentation Male Middle Aged Postoperative Complications/etiology/*prevention & control Prospective Studies *Radio Waves Sternotomy/adverse effects/instrumentation *Surgical Sponges Thoracotomy/adverse effects/instrumentation Young Adult LA - eng N1 - 1528-1140 Inaba, Kenji Okoye, Obi Aksoy, Hande Skiada, Dimitra Ault, Glenn Sener, Stephen Lam, Lydia Benjamin, Elizabeth Demetriades, Demetrios Journal Article Observational Study United States Ann Surg. 2016 Oct;264(4):599-604. doi: 10.1097/SLA.0000000000001872. PY - 2016 SN - 0003-4932 SP - 599-604 ST - The Role of Radio Frequency Detection System Embedded Surgical Sponges in Preventing Retained Surgical Sponges: A Prospective Evaluation in Patients Undergoing Emergency Surgery T2 - Ann Surg TI - The Role of Radio Frequency Detection System Embedded Surgical Sponges in Preventing Retained Surgical Sponges: A Prospective Evaluation in Patients Undergoing Emergency Surgery VL - 264 ID - 181 ER - TY - JOUR AB - Foreign body giant cells (FBGCs) are a hallmark of the foreign body reaction caused by biomaterial implantation and are thought to contribute to biomaterial degradation and the duration of the response. Osteopontin (OPN) is a secreted, acidic matricellular protein with multiple phosphorylation sites that is highly expressed at sites of inflammation. OPN wildtype and knockout mice were implanted with poly(vinyl alcohol) sponges and explanted at 14 days. OPN knockout mice had more foreign body giant cells but fewer macrophages surrounding the implants than their wildtype counterparts. In an in vitro human FBGC assay, addition of soluble OPN was found to reduce macrophage fusion to giant cells. These are the first studies to show a direct inhibitory role of OPN in FBGC formation in response to implantation. © 2005 Elsevier Ltd. All rights reserved. AD - Department of Bioengineering, University of Washington, Box 351720, Seattle, WA 98195, United States Department of Pathology, University of Washington, Seattle, WA 98195, United States Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, ME 04074, United States Department of Chemical Engineering, University of Washington, Seattle, WA 98195, United States Department of Bioengineering, University of Washington, Box 351720, Seattle, WA 98195-1720, United States AU - Tsai, A. T. AU - Rice, J. AU - Scatena, M. AU - Liaw, L. AU - Ratner, B. D. AU - Giachelli, C. M. DB - Scopus DO - 10.1016/j.biomaterials.2005.03.003 IS - 29 KW - Foreign body giant cells Foreign body reaction Knockout mice Macrophages Osteopontin M3 - Article N1 - Cited By :44 Export Date: 10 November 2020 PY - 2005 SP - 5835-5843 ST - The role of osteopontin in foreign body giant cell formation T2 - Biomaterials TI - The role of osteopontin in foreign body giant cell formation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-20444418992&doi=10.1016%2fj.biomaterials.2005.03.003&partnerID=40&md5=40d08b21af5bd649f75b9d19b035e6d5 VL - 26 ID - 1598 ER - TY - JOUR AB - The study objective was to determine the tissue response to polyethylene and/or titanium particles and the role that these play in peri-prosthetic osteolysis in a rabbit model of implant failure. Twenty-two mature rabbits were used. Unilateral tibial arthroplasty was performed on all of them. The test animals received implants that were intentionally rotationally unstable with reference to the host tibia in order to create a model of failure. The test rabbits were divided into three groups. Group 1 consisted of seven rabbits in which only the carrier was implanted. Group 2 consisted of seven rabbits that received only polyethylene particles suspended in the carrier. Group 3 consisted of eight rabbits that received a mixture of polyethylene and titanium alloy particles suspended in the carrier. The rabbits were sacrificed at 6 months post surgery. The entire knee, together with the immediately surrounding soft tissue, was retrieved. The position of the implant in each rabbit was assessed with reference to its alignment to the tibia. The number of inflammatory, foreign-body reactive cells, the presence of neovascularization, edema, and necrosis in the periprosthetic zones were recorded and assessed in a qualitative and semiquantitative manner. Quantitative histomorphometry was used to determine the proportion of implant surface that interfaced with osseous or fibrous tissue. Also assessed was the thickness and maturity of the fibrous tissue and the endosteal remodeling activity in the peri-implant bone counting both osteoclastic and osteoblastic activity. The results showed that implanted particles and misalignment of the implants combined to produce peri-prosthetic bone resorption. Bone resorption was found to be proportional to the degree of misalignment. The animals that received combined polyethylene/titanium particles had a greater degree of foreign-body and inflammatory response with osteolysis than the other groups. The combination of bio-material particles (polyethylene and titanium alloy) produced a greater degree of bone resorption than the single biomaterial particles (polyethylene). The amount of bone resorption surrounding the implant was directly proportional to the degree of misalignment of the implant. © 2004 Wiley Periodicals, Inc. AD - Dept. of Lab. Med. and Pathophysiol., St Michael's Hospital, University of Toronto, 30 Bond Street, Toronto, Ont. M5B 1W8, Canada Division of Orthopedic Surgery, Stanford University Medical Center, Stanford, CA, United States AU - Fornasier, V. L. AU - Goodman, S. B. AU - Protzner, K. AU - Kamel, M. AU - Song, Y. AU - Shojaci, A. DB - Scopus DO - 10.1002/jbm.b.20038 IS - 2 M3 - Article N1 - Cited By :14 Export Date: 10 November 2020 PY - 2004 SP - 179-186 ST - The role of implant alignment on stability and particles on periprosthetic osteolysis - A rabbit model of implant failure T2 - Journal of Biomedical Materials Research - Part B Applied Biomaterials TI - The role of implant alignment on stability and particles on periprosthetic osteolysis - A rabbit model of implant failure UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-3442896766&doi=10.1002%2fjbm.b.20038&partnerID=40&md5=efd4873127b1e88c7a61dc78155f9476 VL - 70 ID - 1623 ER - TY - JOUR AB - Interleukin‐4 (IL‐4) was previously shown to induce extensive macrophage fusion to form foreign‐body giant cells (FBGCs) in vitro. In the present study, our goal was to extend these findings to an in vivo test environment on biomaterials. The subcutaneous cage‐implant system was modified for mice to elucidate IL‐4 participation in mediating FBGC formation in vivo. Exudate leukocyte concentrations from cages containing poly(etherurethane urea) (PEUU A′) and empty cage controls indicated a similar inflammatory response that turned toward resolution by 14 days postimplantation, thus confirming the applicability of the cage‐implant system in mice. FBGC kinetic analysis showed that the formation of mouse FBGCs occurs through the fusion of adherent macrophages at a constant rate up to 14 days of implantation. Purified goat anti‐mouse IL‐4 neutralizing antibody (IL4Ab) or normal goat nonspecific control IgG (gtIgG) at various concentrations, or recombinant murine IL‐4 (muIL4) was injected into the implanted cages containing PEUU A′ every 2 days for 7 days. The injection of IL4Ab significantly decreased the FBGC density on PEUU A′ cage‐implanted in mice, when compared with the nonspecific IgG or PBS injection controls. Conversely, the FBGC density was significantly increased by the injection of muIL4 when compared with nonspecific IgG and PBS injection controls. Adherent macrophage density, FBGC morphology, FBGC average size, and size distribution were not significantly different among IL4Ab, nonspecific control gtIgG, muIL4, and PBS control groups. Our data suggest that IL‐4 participates in FBGC formation on biomaterials in vivo. © 1995 John Wiley & Sons, Inc. Copyright © 1995 John Wiley & Sons, Inc. AD - Department of Macromolecular Science, Case Western Reserve University, Cleveland, Ohio, 44106-4907, United States Institute of Pathology, Case Western Reserve University, Cleveland, Ohio, 44106-4907, United States AU - Kao, W. J. AU - McNally, A. K. AU - Hiltner, A. AU - Anderson, J. M. DB - Scopus DO - 10.1002/jbm.820291014 IS - 10 M3 - Article N1 - Cited By :117 Export Date: 10 November 2020 PY - 1995 SP - 1267-1275 ST - Role for interleukin‐4 in foreign‐body giant cell formation on a poly(etherurethane urea) in vivo T2 - Journal of Biomedical Materials Research TI - Role for interleukin‐4 in foreign‐body giant cell formation on a poly(etherurethane urea) in vivo UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029380449&doi=10.1002%2fjbm.820291014&partnerID=40&md5=9f85763291c484549723dc5eb1aa8303 VL - 29 ID - 1723 ER - TY - JOUR AB - BACKGROUND: Retained surgical items (RSI) are designated as completely preventable "never events". Despite numerous case reports, clinical series, and expert opinions few studies provide quantitative insight into RSI risk factors and their relative contributions to the overall RSI risk profile. Existing case-control studies lack the ability to reliably detect clinically important differences within the long list of proposed risks. This meta-analysis examines the best available data for RSI risk factors, seeking to provide a clinically relevant risk stratification system. METHODS: Nineteen candidate studies were considered for this meta-analysis. Three retrospective, case-control studies of RSI-related risk factors contained suitable group comparisons between patients with and without RSI, thus qualifying for further analysis. Comprehensive Meta-Analysis 2.0 (BioStat, Inc, Englewood, NJ) software was used to analyze the following "common factor" variables compiled from the above studies: body-mass index, emergency procedure, estimated operative blood loss >500 mL, incorrect surgical count, lack of surgical count, >1 subprocedure, >1 surgical team, nursing staff shift change, operation "afterhours" (i.e., between 5 PM and 7 AM), operative time, trainee presence, and unexpected intraoperative factors. We further stratified resulting RSI risk factors into low, intermediate, and high risk. RESULTS: Despite the fact that only between three and six risk factors were associated with increased RSI risk across the three studies, our analysis of pooled data demonstrates that seven risk factors are significantly associated with increased RSI risk. Variables found to elevate the RSI risk include intraoperative blood loss >500 mL (odds ratio [OR] 1.6); duration of operation (OR 1.7); >1 subprocedure (OR 2.1); lack of surgical counts (OR 2.5); >1 surgical team (OR 3.0); unexpected intraoperative factors (OR 3.4); and incorrect surgical count (OR 6.1). Changes in nursing staff, emergency surgery, body-mass index, and operation "afterhours" were not significantly associated with increased RSI risk. CONCLUSIONS: Among the "common risk factors" reported by all three case-control studies, seven synergistically show elevated RSI risk across the pooled data. Based on these results, we propose a risk stratification scheme and issue a call to arms for large, prospective, and multicenter studies evaluating effects of specific changes at the institutional level (i.e., universal surgical counts, radiographic verification of the absence of RSI, and radiofrequency labeling of surgical instruments and sponges) on the risk of RSI. Overall, our findings provide a meaningful foundation for future patient safety initiatives and clinical studies of RSI occurrence and prevention. AD - Department of Surgery, The Ohio State University, Columbus, OH. Electronic address: susan.moffatt-bruce@osumc.edu. Department of Surgery, The Ohio State University, Columbus, OH. AN - 24953990 AU - Moffatt-Bruce, S. D. AU - Cook, C. H. AU - Steinberg, S. M. AU - Stawicki, S. P. DA - Aug DO - 10.1016/j.jss.2014.05.044 DP - NLM ET - 2014/06/24 IS - 2 KW - Foreign Bodies/*epidemiology/prevention & control Humans Iatrogenic Disease/*epidemiology/prevention & control *Intraoperative Period Medical Errors/prevention & control/*statistics & numerical data Risk Factors Meta-analysis Retained foreign body Risk stratification LA - eng N1 - 1095-8673 Moffatt-Bruce, Susan D Cook, Charles H Steinberg, Steven M Stawicki, Stanislaw P Journal Article Meta-Analysis United States J Surg Res. 2014 Aug;190(2):429-36. doi: 10.1016/j.jss.2014.05.044. Epub 2014 May 23. PY - 2014 SN - 0022-4804 SP - 429-36 ST - Risk factors for retained surgical items: a meta-analysis and proposed risk stratification system T2 - J Surg Res TI - Risk factors for retained surgical items: a meta-analysis and proposed risk stratification system VL - 190 ID - 152 ER - TY - JOUR AB - BACKGROUND: Risk factors for medical errors remain poorly understood. We performed a case-control study of retained foreign bodies in surgical patients in order to identify risk factors for this type of error. METHODS: We reviewed the medical records associated with all claims or incident reports of a retained surgical sponge or instrument filed between 1985 and 2001 with a large malpractice insurer representing one third of the physicians in Massachusetts. For each case, we identified an average of four randomly selected controls who underwent the same type of operation during the same six-month period. RESULTS: Our study included 54 patients with a total of 61 retained foreign bodies (of which 69 percent were sponges and 31 percent instruments) and 235 control patients. Thirty-seven of the patients with retained foreign bodies (69 percent) required reoperation, and one died. Patients with retained foreign bodies were more likely than controls to have had emergency surgery (33 percent vs. 7 percent, P<0.001) or an unexpected change in surgical procedure (34 percent vs. 9 percent, P<0.001). Patients with retained foreign bodies also had a higher mean body-mass index and were less likely to have had counts of sponges and instruments performed. In multivariate analysis, factors associated with a significantly increased risk of retention of a foreign body were emergency surgery (risk ratio, 8.8 [95 percent confidence interval, 2.4 to 31.9]), unplanned change in the operation (risk ratio, 4.1 [95 percent confidence interval, 1.4 to 12.4]), and body-mass index (risk ratio for each one-unit increment, 1.1 [95 percent confidence interval, 1.0 to 1.2]). CONCLUSIONS: The risk of retention of a foreign body after surgery significantly increases in emergencies, with unplanned changes in procedure, and with higher body-mass index. Case--control analysis of medical-malpractice claims may identify and quantify risk factors for specific types of errors. AD - Departments of Surgery, Brigham and Women's Hospital, Boston, MA 02115, USA. AN - 12529464 AU - Gawande, A. A. AU - Studdert, D. M. AU - Orav, E. J. AU - Brennan, T. A. AU - Zinner, M. J. DA - Jan 16 DO - 10.1056/NEJMsa021721 DP - NLM ET - 2003/01/17 IS - 3 KW - Analysis of Variance Body Mass Index Case-Control Studies Emergency Treatment Female Foreign Bodies/*etiology/mortality Humans Male Malpractice Medical Errors/*statistics & numerical data Middle Aged Reoperation Risk Factors *Surgical Instruments *Surgical Sponges United States LA - eng N1 - 1533-4406 Gawande, Atul A Studdert, David M Orav, E John Brennan, Troyen A Zinner, Michael J KO2HS11285/HS/AHRQ HHS/United States U18HS11886/HS/AHRQ HHS/United States Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United States N Engl J Med. 2003 Jan 16;348(3):229-35. doi: 10.1056/NEJMsa021721. PY - 2003 SN - 0028-4793 SP - 229-35 ST - Risk factors for retained instruments and sponges after surgery T2 - N Engl J Med TI - Risk factors for retained instruments and sponges after surgery VL - 348 ID - 41 ER - TY - JOUR AB - Incorrect surgical counts after surgery are a perplexing problem for nurses working in the perioperative environment. To determine factors associated with an incorrect surgical count, this cross-sectional, correlational study examined explanatory variables (eg, patient and nurse characteristics, intraoperative circumstances, staff involvement) by using data abstracted from perioperative medical records and primary data collected from perioperative nurses. In the final multivariate analysis, six variables were significantly associated with an incorrect surgical count: a higher surgical risk, a lower body mass index, a complicated procedure, an unplanned procedure, an increased number of perioperative personnel involved, and an increased number of specialty teams involved. AN - 104415748. Language: English. Entry Date: 20121019. Revision Date: 20200708. Publication Type: Journal Article AU - Rowlands, Aletha DB - ccm DO - 10.1016/j.aorn.2012.06.012 DP - EBSCOhost IS - 3 KW - Health Care Errors -- Risk Factors Perioperative Nursing Surgical Count Procedure Body Mass Index Confidence Intervals Correlational Studies Cross Sectional Studies Data Analysis Software Descriptive Statistics Educational Status Human Information Resources Job Experience Logistic Regression Multivariate Analysis Nurses Odds Ratio Personnel Staffing and Scheduling Poisson Distribution Virginia World Wide Web N1 - research; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 0372403. PMID: NLM22935256. PY - 2012 SN - 0001-2092 SP - 272-284 ST - Risk factors associated with incorrect surgical counts T2 - AORN Journal TI - Risk factors associated with incorrect surgical counts UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104415748&site=ehost-live&scope=site VL - 96 ID - 750 ER - TY - JOUR AB - A majority of foreign objects ingested pass through the gastrointestinal tract without any complications. Sometimes, complications such as perforation and adhesions of the neighboring organs occur and surgical treatment becomes necessary. We report the case of a 22-year-old female who was admitted with right flank pain. Past medical history revealed that the patient had accidentally swallowed a headscarf pin 11 months earlier. A computed tomography scan confirmed the swallowed foreign body posterior to and around the ileocecal region. The headscarf pin, causing stenosis and proximal ureteral dilatation, was removed surgically. To the authors' knowledge there has been no previous report of such ureteral obstruction published in the English literature. © 2013 S. Karger AG, Basel. AD - Department of Urology, Memorial Sisli Hospital, Piyalepasa Bulvari, TR-34375 Okmeydani/Istanbul, Turkey Anesthesiology, Memorial Hospital, Istanbul, Turkey AU - Alkan, E. AU - Ozkanli, O. AU - Balbay, D. DB - Scopus DO - 10.1159/000346329 IS - 2 KW - Foreign body Hydronephrosis Ureteral obstruction M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2013 SP - 242-244 ST - Right-sided hydronephrosis secondary to swallowing a headscarf pin T2 - Urologia Internationalis TI - Right-sided hydronephrosis secondary to swallowing a headscarf pin UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84883740376&doi=10.1159%2f000346329&partnerID=40&md5=4667a2f65edfc2c6faaff32b75084688 VL - 91 ID - 1313 ER - TY - JOUR AB - Right-ventricular outflow tract (RVOT) endocarditis is a very rare presentation of right-sided infective endocarditis (RSIE) by brucellosis. RSIE occurs most commonly in immune-suppressed cases and illicit drug abuser. The patients with RSIE and an incompetent immune system usually have a prosthetic foreign body in blood circulation such as catheter, pacemakers, or central venous lines and may be accompanied with tricuspid or pulmonary valve dysfunction. The most common site for RSIE is the tricuspid valve. We describe an exceedingly rare condition of RVOT endocarditis in a patient with brucellosis in which vegetation is attached to a muscle bundle of the RVOT. Despite appropriate antibiotic therapy, the general condition of the patient deteriorated and was finally scheduled for open-heart surgery. The mass was resected and the patient recovered uneventfully and was discharged on the 9th day of surgery with appropriate oral antibiotics. © 2016 King Saud Bin Abdulaziz University for Health Sciences AD - Preventive Cardiovascular Research Centre Kermanshah, Kermanshah University of Medical Sciences, Kermanshah, Iran Department of Anesthesiology, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran AU - Sabzi, F. AU - Heidari, A. AU - Faraji, R. DB - Scopus DO - 10.1016/j.jiph.2016.09.010 IS - 5 KW - Endocarditis Outflow tract Right cardiac chambers M3 - Article N1 - Export Date: 10 November 2020 PY - 2017 SP - 678-680 ST - Right ventricular outflow tract endocarditis caused by brucellosis T2 - Journal of Infection and Public Health TI - Right ventricular outflow tract endocarditis caused by brucellosis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85010931190&doi=10.1016%2fj.jiph.2016.09.010&partnerID=40&md5=c1306e5bdba1f1f6656a77f55b0394ee VL - 10 ID - 1123 ER - TY - JOUR AD - Department of Emergency Medicine, Taipei Medical University, Wan Fang Hospital, Taipei, Taiwan AU - Lee, I. H. AU - Chiu, Y. H. AU - How, C. K. AU - Chen, J. D. AU - Yen, D. H. T. DB - Scopus DO - 10.1097/MAJ.0b013e3181f3cc12 IS - 6 M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2011 SP - 499 ST - Right hip necrotizing fasciitis T2 - American Journal of the Medical Sciences TI - Right hip necrotizing fasciitis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79958133712&doi=10.1097%2fMAJ.0b013e3181f3cc12&partnerID=40&md5=9f6571fc22b0864c53beca4cb1465075 VL - 341 ID - 1433 ER - TY - JOUR AN - 104839660. Language: English. Entry Date: 20110308. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 2 KW - Health Care Errors -- Rhode Island Surgical Equipment and Supplies Surgical Count Procedure -- Standards Rhode Island Hospital Policies Wrong Site Surgery N1 - brief item. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 7810150. PY - 2011 SN - 0190-5066 SP - 20-21 ST - RI fines hospital for surgical errors T2 - Same-Day Surgery TI - RI fines hospital for surgical errors UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104839660&site=ehost-live&scope=site VL - 35 ID - 898 ER - TY - JOUR AD - Diabetic Foot Clinic, Elsie Bertram Diabetes Centre, Norfolk and Norwich University Hospitals NHS Foundation Trust, Colney Lane, Norwich, Norfolk, NR4 7UY, United Kingdom Department of Vascular Surgery, Norfolk and Norwich University Hospitals NHS Foundation Trust, Colney Lane, Norwich, Norfolk, NR4 7UY, United Kingdom Department of Orthopaedic Surgery, Norfolk and Norwich University Hospitals NHS Foundation Trust, Colney Lane, Norwich, Norfolk, NR4 7UY, United Kingdom Department of Microbiology, Norfolk and Norwich University Hospitals NHS Foundation Trust, Colney Lane, Norwich, Norfolk, NR4 7UY, United Kingdom AU - Dhatariya, K. AU - Gooday, C. AU - Morrow, D. AU - Murchison, R. AU - Turner, J. AU - Hutchinson, R. AU - Williams, H. C7 - hcr045 DB - Scopus DO - 10.1093/qjmed/hcr045 IS - 4 M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2012 SP - 365-368 ST - Rhizobium radiobacter wound infection in a patient with diabetes-fact, factitious or just plain unlucky? T2 - QJM TI - Rhizobium radiobacter wound infection in a patient with diabetes-fact, factitious or just plain unlucky? UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84859056904&doi=10.1093%2fqjmed%2fhcr045&partnerID=40&md5=d5a505dc5417a107f11b8169fa75ef88 VL - 105 ID - 1372 ER - TY - JOUR AB - Rhinoliths are rare foreign bodies of the nose formed by in situ mineralization of endogenous or exogenous foreign material. They are often asymptomatic but may have various clinical presentations, with purulent rhinorrhea and nasal obstruction being the most common. They may go unnoticed for a long period and be diagnosed accidentally during a routine examination. We report a 6.5-year-old girl with rhinolithiasis complicated with sinusitis, frontal osteomyelitis and epidural abscess; she had a history dating back four years. AD - Departments of Otolaryngology, Ondokuz Mayis University Faculty of Medicine, Samsun, Turkey Departments of Pediatric Infectious Diseases, Ondokuz Mayis University Faculty of Medicine, Samsun, Turkey Departments of Radiology, Ondokuz Mayis University Faculty of Medicine, Samsun, Turkey AU - Atmaca, S. AU - Belet, N. AU - Şensoy, G. AU - Belet, U. DB - Scopus IS - 2 KW - Epidural abscess Frontal osteomyelitis Rhinolithiasis Sinusitis M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2010 SP - 187-190 ST - Rhinolithiasis: An unusual cause of sinusitis complicated with frontal osteomyelitis and epidural abscess T2 - Turkish Journal of Pediatrics TI - Rhinolithiasis: An unusual cause of sinusitis complicated with frontal osteomyelitis and epidural abscess UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77955480005&partnerID=40&md5=5ea410f3aa0bfaeb0ad5e46fb6d229e7 VL - 52 ID - 1452 ER - TY - JOUR AB - Estimates say 1,500 objects are left inside patients after surgery each year in the United States; two-thirds are sponges. A handheld wand scanning device successfully detects sponges in seconds. The author recommends conducting an initial count prior to surgical incision, a second count at the beginning of wound closure, and a third count before the skin is closed. DB - Medline IS - 10 KW - article hospital department human medical error methodology physician radiofrequency radiation safety surgical sponge United States LA - English M3 - Article N1 - L44686745 2006-11-10 PY - 2006 SN - 1541-1052 SP - 118-120 ST - RFID tags help alert surgeons to problems T2 - Healthcare benchmarks and quality improvement TI - RFID tags help alert surgeons to problems UR - https://www.embase.com/search/results?subaction=viewrecord&id=L44686745&from=export VL - 13 ID - 618 ER - TY - JOUR AB - Six pigs were used to evaluate the influence of three separate modalities on contaminated wounds. Full-thickness skin wounds on the abdomen were contaminated with 104 or 105 Staphylococcus aureus and then closed with one of three methods. The three closure modalities included (1) a new absorbable staple (Insorb™) placed in the subcuticular tissue, (2) a braided Vicryl™ suture, and (3) percutaneous metal staples. Any foreign body material implanted in tissue increases the risk of infection at that site. Wound closure always involves the use of a foreign body. Historically, sutures have been the primary material used to close tissue. The newer synthetic sutures are significangly more biodegradable and cause less infection than sutures composed of protein, such as silk and catgut. Metal staples are also associated with a low risk of infection. Recently, Incisive Surgical, Inc. (Plymouth, Minnesota) has developed an absorbable polymer staple specifically for subcuticular skin closure. The purpose of this study was to compare the new Insorb™ staple to both an absorbable polymer suture and a metal staple. Wound infection was assessed 7 days after closure by clinical signs and quantitative bacterial swabs. The results demonstrated that wounds closed with Insorb™ staples had the lowest incidence (33%) of infection, followed by percutaneous metal staples (44%). All wounds (100%) closed with Vicryl™ suture became infected. The incidence of wound infection directly correlated with the level of quantitative bacterial count at analysis. The Insorb™ staple was associated with significantly reduced closure time, less inflammation and infection, and better aesthetic result compared to Vicryl™. Compared to metal staples, the Insorb™ subcuticular staplers demonstrated comparable closure time without the need for later staple removal. In conclusion, the closure of contaminated wounds with the Insorb™ staples is a superior choice to Vicryl™ suture because they have a significantly (p = 0.009) lower incidence of infection. The Insorb™ staple is a revolutionary advance in subcuticular skin stapling. © 2006 by Begell House, Inc. AD - Department of Plastic Surgery, University of Virginia Health System, Charlottesville, VA, United States University of Virginia Health System, Charlottesville, VA, United States Department of Plastic Surgery, Biomedical Engineering, and Emergency Medicine, University of Virginia Health System, Charlottesville, VA, United States Trauma Specialist, LLP, Legacy Emanuel Hospital, Portland, OR, United States Department of Plastic Surgery, University of Virginia Health System, P.O. Box 801351, Charlottesville, VA 22908-1351, United States AU - Piñeros-Fernandez, A. AU - Salopek, L. S. AU - Rodeheaver, P. F. AU - Drake, D. B. AU - Edlich, R. F. AU - Rodeheaver, G. T. DB - Scopus DO - 10.1615/JLongTermEffMedImplants.v16.i1.30 IS - 1 KW - Aesthetic result Insorb™ Skin staple Staphylococcus aureus Staples Subcuticular Suture Vicryl™ Wound closure speed Wound infection M3 - Article N1 - Cited By :23 Export Date: 10 November 2020 PY - 2006 SP - 19-27 ST - A revolutionary advance in skin closure compared to current methods T2 - Journal of Long-Term Effects of Medical Implants TI - A revolutionary advance in skin closure compared to current methods UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33645462221&doi=10.1615%2fJLongTermEffMedImplants.v16.i1.30&partnerID=40&md5=49b8be36ed9e35b38a661c4580f95948 VL - 16 ID - 1592 ER - TY - JOUR AD - Perioperative Educator, Epworth Eastern, Box Hill, VIC AN - 109794657. Language: English. Entry Date: 20150610. Revision Date: 20151008. Publication Type: Journal Article AU - Thomas, Jane AU - Adcock, Fiona DB - ccm DP - EBSCOhost IS - 1 KW - Surgical Count Procedure -- Evaluation -- Victoria Surgical Count Procedure -- Standards -- Victoria Health Care Errors -- Prevention and Control Surgical Instruments -- Standards Victoria Patient Safety Audit Questionnaires Retained Instruments -- Prevention and Control Organizational Culture Organizational Change Sentinel Event -- Prevention and Control N1 - forms; research; tables/charts. Journal Subset: Australia & New Zealand; Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. Special Interest: Perioperative Care. PY - 2014 SN - 1448-7535 SP - 20-26 ST - A review of existing count practice in the operating suite to achieve best practice and safe patient care T2 - ACORN: The Journal of Perioperative Nursing in Australia TI - A review of existing count practice in the operating suite to achieve best practice and safe patient care UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109794657&site=ehost-live&scope=site VL - 27 ID - 726 ER - TY - JOUR AN - 105133850. Language: English. Entry Date: 20100416. Revision Date: 20150711. Publication Type: Journal Article AU - Halvorson, C. K. DB - ccm DO - 10.1016/j.cpen.2009.11.003 DP - EBSCOhost IS - 1 KW - Patient Safety Perioperative Nursing Surgical Count Procedure Surgical Instruments Health Care Errors -- Prevention and Control Nursing Practice, Evidence-Based Protocols Retained Instruments -- Prevention and Control United States N1 - glossary; review; tables/charts. Journal Subset: Core Nursing; Nursing; USA. NLM UID: 101276516. PY - 2010 SN - 1556-7931 SP - 27-44 ST - Review of best practices and literature on instrument counts T2 - Perioperative Nursing Clinics TI - Review of best practices and literature on instrument counts UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105133850&site=ehost-live&scope=site VL - 5 ID - 904 ER - TY - JOUR AB - An adult patient presented to the emergency department with pharyngeal discomfort on swallowing, persisting several hours after lunch. Transnasal fibre-optic endoscopy performed by an otolaryngologist identified a hypopharyngeal foreign body, and the stalk of a dry leaf partially penetrating the mucosa was easily removed under general anaesthesia. Symptoms regressed completely and the patient was discharged. Two days later he presented again, reporting slight dysphagia without odynophagia or other associated symptoms. Meticulous physical examination by the same otolaryngologist revealed this time a slight asymmetry of the posterior pharyngeal wall. A history of recent pharyngeal trauma and findings on clinical examination raised clinical suspicion of retropharyngeal abscess which was supported by CT scan findings. The diagnosis was confirmed in the operating theatre where a purulent collection was drained under new general anaesthesia. Copyright 2014 BMJ Publishing Group. All rights reserved. AD - Department of Otolaryngology, Head and Neck Surgery, Hôpitaux Universitaires de Genève, Geneva, Switzerland Department of Otolaryngology, Head and Neck and Maxillofacial Surgery, Hôpital Cantonal de Fribourg, Fribourg, Switzerland AU - Vourexakis, Z. AU - Konu, P. DB - Scopus DO - 10.1136/bcr-2014-204010 M3 - Article N1 - Export Date: 10 November 2020 PY - 2014 ST - Retropharyngeal abscess complicating 'innocent' foreign body ingestion T2 - BMJ Case Reports TI - Retropharyngeal abscess complicating 'innocent' foreign body ingestion UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84899681776&doi=10.1136%2fbcr-2014-204010&partnerID=40&md5=4bd3f143ad25d57fd96b3de4329dbe0c ID - 1261 ER - TY - JOUR AB - Migration of total hip arthroplasty components is generally associated with a medial acetabular wall defect and may cause various intrapelvic complications. This is often a result of the destructive bone loss that takes place with infection. To our knowledge, this is the first report that presents complete intrapelvic migration of a femoral stem of total hip arthroplasty due to septic loosening with an intact medial acetabular wall. © 2011 Elsevier Inc.. AD - Department of Orthopaedics and Traumatology, Izmir Ataturk Training and Research Hospital, Izmir, Turkey Department of Radiology, Izmir Ataturk Training and Research Hospital, Izmir, Turkey AU - Yagdi, S. AU - Kazimoglu, C. AU - Dirim, B. AU - Bulut, T. AU - Sener, M. DB - Scopus DO - 10.1016/j.arth.2010.04.035 IS - 6 KW - Postoperative complications Prosthesis-related infection Total hip arthroplasty M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2011 SP - 977.e17-977.e20 ST - Retroperitoneal Migration of a Septically Loose Femoral Component T2 - Journal of Arthroplasty TI - Retroperitoneal Migration of a Septically Loose Femoral Component UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84856343762&doi=10.1016%2fj.arth.2010.04.035&partnerID=40&md5=bc1efe97f7ba5613c2d473df10f7084c VL - 26 ID - 1434 ER - TY - JOUR AB - A 70-year-old male patient presented with abdominal pain, acute renal failure, and fever 2 years after laparoscopic cholecystectomy. During the surgical drainage of the abscess formation on the patient́s right flank, a huge gallstone was found in the retroperitoneum. The patient was dismissed from the hospital 11 days after admission with normal lab panel and restored renal function. © Springer-Verlag 2010. AD - Department of General, Visceral, University of the Saarland, D-66421 Homburg, Saarland, Germany Department of Radiology, University of the Saarland, D-66421 Homburg, Saarland, Germany AU - Justinger, C. AU - Sperling, J. AU - Katoh, M. AU - Kollmar, O. AU - Schilling, M. K. AU - Schuld, J. DB - Scopus DO - 10.1007/s00423-009-0587-4 IS - 3 KW - Acute renal failure Laparoscopic cholecystectomy Lost gallstone Retroperitoneal abscess M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2010 SP - 285-287 ST - Retroperitoneal abscess with consecutive acute renal failure caused by a lost gallstone 2 years after laparoscopic cholecystectomy T2 - Langenbeck's Archives of Surgery TI - Retroperitoneal abscess with consecutive acute renal failure caused by a lost gallstone 2 years after laparoscopic cholecystectomy UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77954681482&doi=10.1007%2fs00423-009-0587-4&partnerID=40&md5=29d2058e805c2362f02c1a49470df344 VL - 395 ID - 1468 ER - TY - JOUR AB - Foreign body in urinary bladder is an unusual finding in urology emergency, which has always caused wide attention. In this case report, we presented a 28-year-old unmarried male who was admitted to the emergency room with magnetic balls in his bladder. An abdominal plain X ray showed metallic dense shadow in the pelvic region. The foreign body was removed under modified cystoscopy and 159 magnetic balls were detected. The patient was discharged without any surgical or postsurgical complications. Cystoscopy is a better option for dealing with a large number of magnetic balls in urinary bladder. © 2019 AD - Department of Urology, Beijing JiShuiTan Hospital, The 4th Medical College of Peking University, Beijing, 100096, China AU - Liu, Z. H. AU - Zhu, X. F. AU - Zhou, N. C7 - 100975 DB - Scopus DO - 10.1016/j.eucr.2019.100975 KW - Cystoscopy Foreign body Magnetic balls Urinary bladder M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2019 ST - Retrieval of 159 magnetic balls from urinary bladder: A case report and literature review T2 - Urology Case Reports TI - Retrieval of 159 magnetic balls from urinary bladder: A case report and literature review UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069671540&doi=10.1016%2fj.eucr.2019.100975&partnerID=40&md5=6571c6a004c7376d584bd7f115366401 VL - 26 ID - 997 ER - TY - JOUR AB - Purpose: Based on the current literature, retinal detachment (RD) is not associated with traumatic chorioretinal rupture (TCR, also known as sclopetaria). The purpose of this study is to present a series of patients with rhegmatogenous retinal detachment associated with TCR. Methods: The records from 3 consecutive patients who sustained TCR were reviewed. The mechanism of TCR, initial presentation and visual acuity, extent of detachment and surgical management are presented Results: Case 1: A 40-year-old man presented one week after an injury with an 8 cm nail embedded in the right orbit extending into the frontal lobe. Visual acuity (VA) was light perception (LP) and there was dense vitreous hemorrhage. TCR and hemorrhagic choroidal detachment were noted as the vitreous hemorrhage cleared. Serial B-scans showed a new retinal detachment 2 weeks after presentation. The patient underwent pars plana vitrectomy (PPV) and lensectomy (PPL), peeling of tractional membranes (MP), and silicone oil (SO) tamponade. One month later, he developed a recurrent inferior detachment which was treated with a repeat PPV with a 180 degree inferior retinectomy and SO tamponade. Case 2: A 14-year-old boy sustained a BB pellet injury in his left orbit. VA was count fingers at one foot and he had vitreous hemorrhage and superior TCR. B-scan demonstrated an attached retina. The vitreous hemorrhage started to clear, but one month after the injury, he developed a new macula-off retinal detachment with a break superiorly at the edge of the TCR with proliferative vitreoretinopathy (PVR). The patient underwent PPV/scleral buckle (SB)/SO tamponade. Case 3: A 65-year-old man sustained a blast injury that resulted in a metallic foreign body that penetrated his right orbit and lodged in the left frontal lobe. VA was LP. Fundus exam revealed vitreous hemorrhage, bullous subhyaloid hemorrhage inferiorly and TCR superiorly. One week after the injury he developed a shallow RD noted on serial B-scans. He underwent a PPV/SB/MP/SO with a 180-degree superior retinectomy, and was also found to have subretinal hemorrhage and PVR. Three months later, the patient developed a recurrent inferior RD with PVR that was treated with a repeat PPV/PPL/180 degree inferior retinectomy and SO tamponade. Conclusions: TCR can be associated with subacute RD in the post-traumatic period and these patients should be followed very closely. AD - T.D. Papakostas, Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, United States AU - Papakostas, T. D. AU - Yonekawa, Y. AU - Wu, D. M. AU - Miller, J. B. AU - Eldman, P. B. VPeter B. V. AU - Chee, Y. E. AU - Husain, D. AU - Eliott, D. DB - Embase IS - 13 KW - endogenous compound silicone oil T lymphocyte receptor adolescent adult aged B scan blast injury case report child choroid detachment finger foot foreign body frontal lobe human information processing lensectomy male membrane pars plana vitrectomy perception retina detachment retina macula lutea rupture scleral buckle stomach fundus surgery visual acuity vitreoretinopathy vitreous hemorrhage LA - English M3 - Conference Abstract N1 - L616119203 2017-05-16 PY - 2014 SN - 0146-0404 SP - 1119 ST - Retinal detachment in traumatic chorioretinal rupture (sclopetaria) T2 - Investigative Ophthalmology and Visual Science TI - Retinal detachment in traumatic chorioretinal rupture (sclopetaria) UR - https://www.embase.com/search/results?subaction=viewrecord&id=L616119203&from=export VL - 55 ID - 447 ER - TY - JOUR AB - We report the outcome in 2 eyes of 2 patients with retained silicone oil droplets in the anterior chamber drainage angle after the use of an ophthalmic viscosurgical device (OVD) during cataract surgery. Silicone oil droplets were observed when the OVD was injected into the anterior chamber during phacoemulsification. Despite removal by irrigation and aspiration, droplets were observed in the anterior chamber during the immediate postoperative period. At 15 months, they were observed in the drainage angle. The retained silicone did not produce untoward side effects in the eyes. Silicone oil is a common contaminant in OVDs but appears to be inert and harmless when retained in small amounts in the anterior chamber drainage angle. © 2007 ASCRS and ESCRS. AD - Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong AU - Lam, P. T. H. AU - Cheng, A. C. O. AU - Rao, S. AU - Lam, D. S. C. DB - Scopus DO - 10.1016/j.jcrs.2007.07.011 IS - 11 M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2007 SP - 1994-1996 ST - Retention of silicone oil droplets from ophthalmic viscosurgical devices in the drainage angle of 2 eyes T2 - Journal of Cataract and Refractive Surgery TI - Retention of silicone oil droplets from ophthalmic viscosurgical devices in the drainage angle of 2 eyes UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-35348960908&doi=10.1016%2fj.jcrs.2007.07.011&partnerID=40&md5=9123c6ab26ec0dbd3d91ff2ebb07e70a VL - 33 ID - 1550 ER - TY - JOUR AN - 105355401. Language: English. Entry Date: 20090731. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical AU - Cash, A. DB - ccm DP - EBSCOhost IS - 1 KW - Foreign Bodies -- Legislation and Jurisprudence -- United States Liability, Legal Retained Instruments -- Prevention and Control Radiography Surgical Count Procedure Surgical Sponges United States N1 - Peer Reviewed; USA. NLM UID: 100889788. PY - 2005 SN - 1344-6223 SP - 33-39 ST - Retention of foreign bodies after a procedure T2 - Legal Medicine TI - Retention of foreign bodies after a procedure UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105355401&site=ehost-live&scope=site VL - 7 ID - 862 ER - TY - JOUR AB - Study Objective: To raise awareness of the potential problem of retained vaginal foreign body in minimally invasive gynecological surgeries and to suggest ways to avoid it. Design: Case review of 2 consecutive cases of minimally invasive gynecological surgeries that were complicated by retained surgical object in the vagina and occurred within 2 consecutive years. Setting: Tertiary care teaching hospital in Southeast Michigan. Patients: 2 patients who had minimally invasive gynecological surgeries that were complicated by a retained surgical object in the vagina and occurred within 2 consecutive years in the same institution. Measurements and Main Results: The first case is a retained asepto bulb after a robotic-assisted total laparoscopic hysterectomy. The second case is a retained surgical sponge after a laparoscopic ovarian cystectomy. Both patients did well after removal of the foreign body from the vagina without major complications. Conclusion: Unfortunately, the counting system and radiographic screening for high risk cases are not reliable methods to prevent retained foreign objects. Communication is always key and standardization of the language in the operating room is essential. Performing two separate counts for the vaginal and the abdominal procedures as well as applying a routine systematic digital vaginal exam at the end of the procedure are two easy steps that could decrease the risk of retained surgical items in a patient's body. (Figure Presented). AD - T. Toubia, Obstetrics and Gynecology, Henry Ford Hospital, Detroit, MI, United States AU - Toubia, T. AU - Sangha, R. DB - Embase IS - 6 KW - gynecologic surgery gynecology foreign body human patient vagina risk procedures United States surgical sponge operating room cystectomy hysterectomy teaching hospital language standardization interpersonal communication screening tertiary health care LA - English M3 - Conference Abstract N1 - L71479642 2014-07-21 PY - 2013 SN - 1553-4650 SP - S148 ST - Retained vaginal foreign body in minimally invasive gynecological surgeries T2 - Journal of Minimally Invasive Gynecology TI - Retained vaginal foreign body in minimally invasive gynecological surgeries UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71479642&from=export VL - 20 ID - 497 ER - TY - JOUR AB - Retained surgical sponges (RSS) are an avoidable complication following surgical operations. RSS can elicit either an early exudative-type reaction or a late aseptic fibrous tissue reaction. They may remain asymptomatic for long time; when present, symptomatology varies substantially and includes septic complications (abscess formation, peritonitis) or fibrous reaction resulting in adhesion formation or fistulation into adjacent hollow organs or externally. Plain radiograph may be useful for the diagnosis; however, computed tomography is the method of choice to establish correct diagnosis preoperatively. Removal of RSS is always indicated to prevent further complications. This is usually accomplished by open surgery; rarely, endoscopic or laparoscopic removal may be successful. Prevention is of key importance to avoid not only morbidity and even mortality but also medicolegal consequences. Preventive measures include careful counting, use of sponges marked with a radiopaque marker, avoidance of use of small sponges during abdominal procedures, careful examination of the abdomen by the operating surgeon before closure, radiograph in the operating theater (either routinely or selectively), and recently, usage of barcode and radiofrequency identification technology. AD - 4th Department of Surgery, Athens University, Medical School, ATTIKON U. Hospital, Arkadias 19-21, 115 26, Athens, Greece. georgesakorafas@yahoo.com AN - 20652587 AU - Sakorafas, G. H. AU - Sampanis, D. AU - Lappas, C. AU - Papantoni, E. AU - Christodoulou, S. AU - Mastoraki, A. AU - Safioleas, M. DA - Nov DO - 10.1007/s00423-010-0684-4 DP - NLM ET - 2010/07/24 IS - 8 KW - *Abdomen/surgery Delayed Diagnosis Diagnosis, Differential Diagnostic Imaging Foreign Bodies/complications/*diagnosis/prevention & control/surgery Foreign-Body Migration/complications/diagnosis/prevention & control/surgery Humans Laparoscopy Malpractice/*legislation & jurisprudence *Medical Errors Reoperation Risk Factors Sensitivity and Specificity *Surgical Sponges LA - eng N1 - 1435-2451 Sakorafas, George H Sampanis, Dimitrios Lappas, Christos Papantoni, Eva Christodoulou, Spyros Mastoraki, Aikaterini Safioleas, Michael Journal Article Review Germany Langenbecks Arch Surg. 2010 Nov;395(8):1001-7. doi: 10.1007/s00423-010-0684-4. Epub 2010 Jul 22. PY - 2010 SN - 1435-2443 SP - 1001-7 ST - Retained surgical sponges: what the practicing clinician should know T2 - Langenbecks Arch Surg TI - Retained surgical sponges: what the practicing clinician should know VL - 395 ID - 99 ER - TY - JOUR AB - BACKGROUND: Retained surgical items (RSIs) are serious events with a high potential to harm patients. It is estimated that as many as 1 in 5,500 operations result in an RSI, and sponges are most commonly involved. The adverse outcomes, additional medical care needed, and medico-legal costs associated with these events are substantial. The objective of this analysis was to advance our understanding of the occurrence of RSIs, the methods of prevention, and the costs involved. STUDY DESIGN: Incident reports entered into the University HealthSystem Consortium (UHC) Safety Intelligence database on incorrect surgical counts and RSIs were analyzed. Reported cases of retained surgical sponges at organizations that use radiofrequency (RF) technology and those that do not were compared. A cost-benefit analysis on adopting RF technology was conducted. RESULTS: Five organizations that implemented RF technology between 2008 and 2012 collectively demonstrated a 93% reduction in the rate of reported retained surgical sponges. By comparison, there was a 77% reduction in the rate of retained sponges at 5 organizations that do not use RF technology. The UHC cost-benefit analysis showed that the savings in x-rays and time spent in the operating room and in the medical and legal costs that were avoided outweighed the expenses involved in using RF technology. CONCLUSIONS: Current standards for manual counting of sponges and the use of radiographs are not sufficient to prevent the occurrence of retained surgical sponges; our data support the use of adjunct technology. We recommend that hospitals evaluate and consider the use of an adjunct technology. AD - University HealthSystem Consortium, Chicago, IL. Electronic address: williams@uhc.edu. University HealthSystem Consortium, Chicago, IL. University of Iowa College of Nursing, Iowa City, IA. University of Kentucky, UK HealthCare, Lexington, KY. AN - 25081938 AU - Williams, T. L. AU - Tung, D. K. AU - Steelman, V. M. AU - Chang, P. K. AU - Szekendi, M. K. DA - Sep DO - 10.1016/j.jamcollsurg.2014.03.052 DP - NLM ET - 2014/08/02 IS - 3 KW - Cost-Benefit Analysis Foreign Bodies/*diagnosis/*economics/etiology/prevention & control Humans *Radio Waves Retrospective Studies *Risk Management *Surgical Sponges LA - eng N1 - 1879-1190 Williams, Tamara L Tung, Derrick K Steelman, Victoria M Chang, Phillip K Szekendi, Marilyn K Journal Article United States J Am Coll Surg. 2014 Sep;219(3):354-64. doi: 10.1016/j.jamcollsurg.2014.03.052. Epub 2014 May 10. PY - 2014 SN - 1072-7515 SP - 354-64 ST - Retained surgical sponges: findings from incident reports and a cost-benefit analysis of radiofrequency technology T2 - J Am Coll Surg TI - Retained surgical sponges: findings from incident reports and a cost-benefit analysis of radiofrequency technology VL - 219 ID - 153 ER - TY - JOUR AB - BACKGROUND: Unintended retention of foreign bodies remain the most frequently reported sentinel events. Surgical sponges account for the majority of these retained items. The purpose of this study was to describe reports of unintentionally retained surgical sponges (RSS): the types of sponges, anatomic locations, accuracy of sponge counts, contributing factors, and harm, in order to make recommendations to improve perioperative safety. METHODS: A retrospective review was undertaken of unintentionally RSS voluntarily reported to The Joint Commission Sentinel Event Database by healthcare facilities over a 5-year period (October 1, 2012- September 30, 2017). Event reports involving surgical sponges were reviewed for patients undergoing surgery, invasive procedures, or child birth. RESULTS: A total of 319 events involving RSS were reported. Sponges were most frequently retained in the abdomen or pelvis (50.2%) and the vagina (23.9%). Events occurred in the Operating Room (64.1%), Labor and Delivery (32.7%) and other procedural areas (3.3%). Of the events reported, 318 involved 1 to 12 contributing factors totaling 1430 in 13 different categories, most frequently in human factors and leadership. In 69.6% of reports, the harm was an unexpected additional care or extended stay. Severe temporary harm was associated with 14.7% of the events. One patient died as a result of the retained sponge. CONCLUSIONS: Because of the complexity of perioperative patient care, the multitude of contributing factors that are difficult to control, and the potential benefit of radiofrequency sponge detection, we recommend that this technology be considered in areas where surgery is performed and in Labor and Delivery. AD - 1The University of Iowa College of Nursing, 50 Newton Road, Iowa City, IA 52242-1121 USA. ISNI: 0000 0004 1936 8294. GRID: grid.214572.7 2The Joint Commission, 1 Renaissance Boulevard, Oak Brook Terrace, IL 60181 USA. ISNI: 0000 0001 2113 0902. GRID: grid.420254.5 3The University of Iowa Carver College of Medicine, 451 Newton Road, Iowa City, IA 52242 USA. ISNI: 0000 0004 1936 8294. GRID: grid.214572.7 AN - 29988638 AU - Steelman, V. M. AU - Shaw, C. AU - Shine, L. AU - Hardy-Fairbanks, A. J. C2 - PMC6027759 DO - 10.1186/s13037-018-0166-0 DP - NLM ET - 2018/07/11 KW - Adverse event Gossypiboma Labor and delivery Obstetrics Patient safety Sponges Surgery not meet the regulatory definition of human subjects research.Not applicable.VS has received honoraria from Medtronic and is PI on studies for which the University of Iowa received grant money from Medtronic and RF Surgical. For the remaining authors, none were declared.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. LA - eng N1 - 1754-9493 Steelman, Victoria M Shaw, Clarissa Shine, Laurel Hardy-Fairbanks, Abbey J Journal Article Patient Saf Surg. 2018 Jun 29;12:20. doi: 10.1186/s13037-018-0166-0. eCollection 2018. PY - 2018 SN - 1754-9493 (Print) 1754-9493 SP - 20 ST - Retained surgical sponges: a descriptive study of 319 occurrences and contributing factors from 2012 to 2017 T2 - Patient Saf Surg TI - Retained surgical sponges: a descriptive study of 319 occurrences and contributing factors from 2012 to 2017 VL - 12 ID - 218 ER - TY - JOUR AB - INTRODUCTION: Retained sponges and instruments (RSI) due to surgery are a recognised medical 'never event' and have catastrophic implications for patients, healthcare professionals and medical care providers. The aim of this review was to elucidate the extent of the problem of RSI and to identify preventative strategies. METHODS: A comprehensive literature search was performed on MEDLINE(®), Embase™, the Science Citation Index and Google™ Scholar for articles published in English between January 2000 and June 2012. Studies outlining the incidence, risk, management and attempts to prevent RSI following surgical intervention were retrieved. RESULTS: The overall incidence of RSI is low although its incidence is substantially higher in operations performed on open cavities. Sponges are the most commonly retained item when compared with needles and instruments. Clinical presentation is varied, leading to avoidable morbidity, and the error is indefensible medicolegally. Risk factors include emergency operations, operations involving unexpected change in procedure, raised body mass index, and a failure to perform accurate sponge and instrument counts. The existing strategy for prevention is manual counting of sponges and instruments undertaken by surgical personnel. This, however, is fallible. Computer assisted counting of sponges using barcodes and gauze sponges tagged with a radiofrequency identification device aiding manual counting have been trialled recently, with success. CONCLUSIONS: Vigilance among operating theatre personnel is paramount if RSI is to be prevented. Prospective multicentre trials to assess efficacy of new technologies aiding manual counting should be undertaken if this medical error is to be eliminated completely. AD - Nottingham University Hospitals NHS Trust, Queen's Medical Centre, Nottingham, UK. AN - 23484986 AU - Hariharan, D. AU - Lobo, D. N. C2 - PMC4098594 DA - Mar DO - 10.1308/003588413x13511609957218 DP - NLM ET - 2013/03/15 IS - 2 KW - Early Diagnosis Foreign Bodies/etiology/*prevention & control Humans Incidence Medical Errors/*prevention & control *Needles Risk Factors *Surgical Instruments *Surgical Sponges LA - eng N1 - 1478-7083 Hariharan, D Lobo, D N Journal Article Review Ann R Coll Surg Engl. 2013 Mar;95(2):87-92. doi: 10.1308/003588413X13511609957218. PY - 2013 SN - 0035-8843 (Print) 0035-8843 SP - 87-92 ST - Retained surgical sponges, needles and instruments T2 - Ann R Coll Surg Engl TI - Retained surgical sponges, needles and instruments VL - 95 ID - 136 ER - TY - JOUR AB - Imaging within 24 to 48 hours after most neurosurgical procedures is a routine practice. Nonresorbable surgical sponges have radiopaque filaments readily visible on CT scans and plain film radiographs. However, the proton-poor barium sulfate responsible for this radio-opacity is generally not detectable on MR imaging in the immediate post-operative period. Findings on MR imaging become more evident with elapsing time and when a foreign-body reaction to the sponge manifests as a mass lesion, which can mimic residual or recurrent intracranial tumor or abscess. Although preventive measures by our surgical colleagues to ensure accurate and correct sponge counts before and after wound closure is paramount, even the most fastidious efforts may rarely result in an inadvertently retained surgical sponge. The role of the radiologist is to recognize the imaging findings of this entity and its potential complications so that appropriate and prompt management can be initiated. AD - Department of Neuroradiology, University of Pennsylvania, Philadelphia, PA 19104, USA. AN - 19213821 AU - Kim, A. K. AU - Lee, E. B. AU - Bagley, L. J. AU - Loevner, L. A. C2 - PMC7051333 DA - Jun DO - 10.3174/ajnr.A1469 DP - NLM ET - 2009/02/14 IS - 6 KW - Adult Aged Brain Injuries/*etiology/*pathology Craniotomy/*adverse effects Female Foreign Bodies/*diagnosis/*etiology Humans Magnetic Resonance Imaging/*methods Male Middle Aged Surgical Sponges/*adverse effects LA - eng N1 - 1936-959x Kim, A K Lee, E B Bagley, L J Loevner, L A Case Reports Journal Article AJNR Am J Neuroradiol. 2009 Jun;30(6):1270-2. doi: 10.3174/ajnr.A1469. Epub 2009 Feb 12. PY - 2009 SN - 0195-6108 (Print) 0195-6108 SP - 1270-2 ST - Retained surgical sponges after craniotomies: imaging appearances and complications T2 - AJNR Am J Neuroradiol TI - Retained surgical sponges after craniotomies: imaging appearances and complications VL - 30 ID - 87 ER - TY - JOUR AB - OBJECTIVE: Retained surgical sponges are seldom reported due to medicolegal implications. Awareness of this problem among surgeons and radiologists is essential to avoid unnecessary morbidity. We present our experience with this entity and review the related literature. METHODS: The medical records of 11 patients who were diagnosed as having retained surgical sponges from 1990 to 2003 were reviewed. RESULTS: The incidence was 1:5,027 inpatient operations. There were four males and seven females with a median age of 45 years. The original operations were gynaecological (n=4), general (n=4), urological (n=2) and laminectomy (n=1). In seven cases, the original operation was performed on an emergency basis. Five patients were obese. A presumed correct sponge count was documented in eight cases. The median time between the original procedure and diagnosis of retained sponges was 12 months. The tentative diagnosis was intestinal obstruction (4 patients), urinary tract infection (1 patient), Crohn's disease (1 patient) and tumour recurrence (1 patient). The correct diagnosis was suggested in the remaining four patients. Surgical removal of the retained sponges was carried out in all cases except one, in which the patient passed the sponge spontaneously through the rectum. CONCLUSION: Retained sponges are more common in obese patients and after emergency surgery. A high degree of suspicion is important for preoperative diagnosis. Despite the use of radio-opaque sponges and thorough sponge counting, this moribund mishap still occurs. Although human errors cannot be completely abolished, continuous medical training and strict adherence to regulations should reduce the incidence to a minimum. AD - Department of Surgery, Faculty of Medicine, King Abdullah University Hospital, Jordan University of Science and Technology, Irbid, Jordan. banihani60@yahoo.com AN - 15851364 AU - Bani-Hani, K. E. AU - Gharaibeh, K. A. AU - Yaghan, R. J. DA - Apr DO - 10.1016/s1015-9584(09)60273-6 DP - NLM ET - 2005/04/27 IS - 2 KW - Adult Female Foreign Bodies/diagnostic imaging/*epidemiology Humans Incidence Jordan/epidemiology Male Medical Errors/*prevention & control/statistics & numerical data Middle Aged Obesity Postoperative Complications/diagnostic imaging/*epidemiology Radiography Retrospective Studies Risk Factors *Surgical Sponges LA - eng N1 - Bani-Hani, Kamal E Gharaibeh, Kamal A Yaghan, Rami J Journal Article Review China Asian J Surg. 2005 Apr;28(2):109-15. doi: 10.1016/s1015-9584(09)60273-6. PY - 2005 SN - 1015-9584 (Print) 1015-9584 SP - 109-15 ST - Retained surgical sponges (gossypiboma) T2 - Asian J Surg TI - Retained surgical sponges (gossypiboma) VL - 28 ID - 52 ER - TY - JOUR AB - Retained surgical sponge events continue to occur despite the implementation of preventive surgical count policies, procedures, and adjunct technologies to manual counting. Such intraoperative mistakes can cause chronic nonspecific symptoms during the early postoperative period. When discovered years after surgery, they raise thorny medicolegal questions. We describe two cases from our practice that illustrate the need to identify the responsibility of the surgical team, as delineated in ministerial directives and the current legal framework, as well as the difficulty in evaluating clinical actions taken at different times and in different settings, with regard to the permanent health damage incurred by sponge retention. Finally, we discuss prevention actions operating room staff should take to reduce the risk of retained surgical sponges. AD - Departmental Section of Legal Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, A.O.U., "G. Martino" Via Consolare Valeria n. 1, 98100 Messina, Italy. Electronic address: patrizia.gualniera@unime.it. Departmental Section of Legal Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, A.O.U., "G. Martino" Via Consolare Valeria n. 1, 98100 Messina, Italy. Electronic address: sscurria@unime.it. AN - 29413994 AU - Gualniera, P. AU - Scurria, S. DA - Mar DO - 10.1016/j.legalmed.2018.01.003 DP - NLM ET - 2018/02/08 KW - Female *Foreign Bodies/prevention & control Humans Liability, Legal Medical Errors/*prevention & control Middle Aged Operating Room Technicians/*legislation & jurisprudence Postoperative Complications/*etiology Clinical risk management Damage Prevention Professional liability Retained sponge Surgery LA - eng N1 - 1873-4162 Gualniera, Patrizia Scurria, Serena Case Reports Journal Article Ireland Leg Med (Tokyo). 2018 Mar;31:78-81. doi: 10.1016/j.legalmed.2018.01.003. Epub 2018 Feb 1. PY - 2018 SN - 1344-6223 SP - 78-81 ST - Retained surgical sponge: Medicolegal aspects T2 - Leg Med (Tokyo) TI - Retained surgical sponge: Medicolegal aspects VL - 31 ID - 208 ER - TY - JOUR AB - Retained surgical items continue to occur despite widespread implementation of prevention systems such as the surgical count, which has limited utility owing to its reliance on human performance. The most important risk factors for these events are poor communication in the operating room and inconsistent adherence to protocol. New technologies show efficacy in preventing retained surgical items and partially mitigating the poor reliability of the manual count. Additionally, efforts to address systemic and environmental sources of error have demonstrated success in reducing the incidence of retained surgical items. Here, we present the surprising case of a patient with a retained surgical sponge presenting as a soft tissue mass four decades after his surgery. AD - Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL 33431, USA. AN - 32082685 AU - Koek, A. Y. C2 - PMC6995311 of this paper. DO - 10.1155/2020/1230173 DP - NLM ET - 2020/02/23 LA - eng N1 - 2090-6919 Koek, Adriana Y Orcid: 0000-0002-4806-3743 Case Reports Case Rep Surg. 2020 Jan 15;2020:1230173. doi: 10.1155/2020/1230173. eCollection 2020. PY - 2020 SN - 2090-6900 (Print) SP - 1230173 ST - Retained Surgical Sponge Presenting Four Decades Later as a Rapidly Growing Soft Tissue Mass T2 - Case Rep Surg TI - Retained Surgical Sponge Presenting Four Decades Later as a Rapidly Growing Soft Tissue Mass VL - 2020 ID - 242 ER - TY - JOUR AB - BACKGROUND: Gossypiboma, the term for a retained sponge, is an underestimated occurrence related to gynecologic surgery. The postoperative presentation can be acute or subacute with symptoms that include pelvic pain. CASE: A 39-year-old G7P3043 female presented with chronic pelvic pain. Her only past surgeries were 16 and 21 years prior. After failing to respond to conservative options, she was taken to the operating room for a hysterectomy and possible salpingoophorectomy. During the surgery, a retained sponge was found and removed. Postoperatively, the pain resolved completely. CONCLUSION: Although gossypiboma is an uncommon cause of chronic pelvic pain, patients can present years later with minimal complications other than discomfort. Accurate sponge and instrument counts, along with radiologic evaluation when a discrepancy is found, can be helpful. Newer technologies are also being developed to help avoid this complication. AD - Department of ObGyn, Hartford Hospital, Hartford, CT, USA. AN - 17902383 AU - Nieves, L. AU - Schnatz, P. F. AU - Sahakyan, M. AU - Sorosky, J. I. DA - Sep DP - NLM ET - 2007/10/02 IS - 8 KW - Adult Chronic Disease Female Foreign Bodies/*complications/pathology/surgery Humans Pelvic Pain/*etiology *Peritoneum Surgical Sponges/*adverse effects Treatment Outcome LA - eng N1 - Nieves, Lucybeth Schnatz, Peter F Sahakyan, Marine Sorosky, Joel I Case Reports Journal Article United States Conn Med. 2007 Sep;71(8):461-3. PY - 2007 SN - 0010-6178 (Print) 0010-6178 SP - 461-3 ST - A retained surgical sponge presenting as chronic pelvic pain T2 - Conn Med TI - A retained surgical sponge presenting as chronic pelvic pain VL - 71 ID - 67 ER - TY - JOUR AB - OBJECTIVE: A review was performed to investigate the frequency of occurrence and outcome of patients who have retained surgical sponges. METHODS: Closed case records from the files of the Medical Professional Mutual Insurance Company (ProMutual, Boston, MA) involving a claim of retained surgical sponges were reviewed for a 7-year period. RESULTS: Retained sponges occurred in 40 patients, comprising 48% of all closed claims for retained foreign bodies. A falsely correct sponge count after an abdominal procedure was documented in 76% of these claims. Ten percent of claims involved vaginal deliveries and minor non-body cavity procedures, for which no sponge count was performed. Total indemnity payments were $2,072,319, and defense costs were $572,079. In three cases, the surgeon was deemed responsible by the court despite the nursing staff's admitting liability and evidence presented that the surgeon complied completely with the standard of care. A wide range of indemnity payments was made despite a remarkable similarity of outcome in the patients studied. CONCLUSIONS: Despite the rarity of the reporting of a retained surgical sponge, this occurrence appears to be encountered more commonly than generally is appreciated. Operating teams should ensure that sponges be counted for all vaginal and any incisional procedures at risk for retaining a sponge. In addition, the surgeon should not unquestioningly accept correct count reports, but should develop the habit of performing a brief but thorough routine postprocedure wound/body cavity exploration before wound closure. The strikingly similar outcome for most patients would argue for a standardized indemnity payment being made without the need for adversarial legal procedures. AD - Department of Surgery, Department of Veterans Affairs Medical Centre, Manchester, NH 03104, USA. AN - 8678622 AU - Kaiser, C. W. AU - Friedman, S. AU - Spurling, K. P. AU - Slowick, T. AU - Kaiser, H. A. C2 - PMC1235250 DA - Jul DO - 10.1097/00000658-199607000-00012 DP - NLM ET - 1996/07/01 IS - 1 KW - *Abdomen Costs and Cost Analysis Female Foreign Bodies/economics/*epidemiology Humans Insurance, Liability/legislation & jurisprudence/statistics & numerical data Male Malpractice/economics/legislation & jurisprudence/*statistics & numerical data Massachusetts/epidemiology Postoperative Complications/*economics/epidemiology Surgical Sponges/*adverse effects/economics/statistics & numerical data LA - eng N1 - 1528-1140 Kaiser, C W Friedman, S Spurling, K P Slowick, T Kaiser, H A Journal Article Ann Surg. 1996 Jul;224(1):79-84. doi: 10.1097/00000658-199607000-00012. PY - 1996 SN - 0003-4932 (Print) 0003-4932 SP - 79-84 ST - The retained surgical sponge T2 - Ann Surg TI - The retained surgical sponge VL - 224 ID - 24 ER - TY - JOUR AB - BACKGROUND: Retained foreign bodies are relatively uncommon and probably underreported in the tropics. Largely preventable errors, they cause harm to both the patient and the medical practitioner. CASE PRESENTATION AND MANAGEMENT: A 32 year old primigravida with recurrent lower abdominal pain in pregnancy. She had myomectomy a year earlier at a private hospital in which the endometrium was inadvertently breached. She subsequently had an elective caesarean section at 38 weeks and 2 days gestational age. Intra-operative findings were adhesive bands between the uterus and loops of bowel and a round bodied surgical needle attached by adhesions anteriorly to the lower segment. Her post operative care was uneventful and she was discharged home on the 3rd day post operation. CONCLUSION: Retained surgical foreign body (RSFB) could pose a diagnostic dilemma as in the case of this patient with recurrent lower abdominal pain in pregnancy. Meticulous instrument count should include sutures and needles. AN - 26234126 AU - Obajimi, G. O. AU - Oranye, B. C. DA - Dec DP - NLM ET - 2015/08/04 IS - 4 KW - Adult Cesarean Section Female Foreign Bodies/*etiology Humans Needles/*adverse effects Pregnancy Surgical Instruments/*adverse effects Tissue Adhesions/etiology Uterine Myomectomy/*adverse effects/*instrumentation LA - eng N1 - Obajimi, G O Oranye, B C Case Reports Letter Nigeria Afr J Med Med Sci. 2014 Dec;43(4):365-7. PY - 2014 SN - 0309-3913 (Print) 0309-3913 SP - 365-7 ST - Retained surgical needle post myomectomy, an uncommon mishap T2 - Afr J Med Med Sci TI - Retained surgical needle post myomectomy, an uncommon mishap VL - 43 ID - 165 ER - TY - JOUR AB - Although the incidence of retained surgical items (RSIs) is low, it is nevertheless an important preventable cause of patient injury that can ultimately lead to the patient's death and to subsequent high medical and legal costs. Unintentional RSI is the cause of 70% of re-interventions, with a morbidity of 80% and mortality of 35%. The most common RSIs are sponges or gauze (gossypiboma or textiloma), while retained surgical instruments and needles are rare. Perioperative counting of equipment and materials is the most common method of screening for RSIs, while a diagnosis can later be confirmed by the clinical appearance and by imaging studies. We present a rare case of a 43-year-old patient who was admitted to our hospital because of two retained needles following a cesarean section, despite several subsequent laparotomies. One needle had been removed previously, but in addition to the remaining needle, we also removed a retained gauze. The diagnosis of RSIs is extremely important, and safe surgical practices including the addition of new imaging technologies should be encouraged to detect RSIs. AD - 1 Division of Gynecology and Perinatology, University of Maribor Clinical Center, Maribor, Slovenia. 2 Department of Gynecology and Obstetrics, Faculty of Medicine, University of Maribor, Maribor, Slovenia. AN - 30222013 AU - Gavrić Lovrec, V. AU - Cokan, A. AU - Lukman, L. AU - Arko, D. AU - Takač, I. C2 - PMC6259383 DA - Nov DO - 10.1177/0300060518788247 DP - NLM ET - 2018/09/18 IS - 11 KW - Adnexa Uteri/*surgery Adult Bandages/*adverse effects Cesarean Section/*adverse effects Female Foreign Bodies/diagnostic imaging/*etiology Humans Pelvis/diagnostic imaging Pregnancy Ultrasonography Retained surgical item cesarean section gauze imaging needle surgery surgical count LA - eng N1 - 1473-2300 Gavrić Lovrec, Vida Cokan, Andrej Lukman, Lara Arko, Darja Takač, Iztok Case Reports Journal Article Review J Int Med Res. 2018 Nov;46(11):4775-4780. doi: 10.1177/0300060518788247. Epub 2018 Sep 17. PY - 2018 SN - 0300-0605 (Print) 0300-0605 SP - 4775-4780 ST - Retained surgical needle and gauze after cesarean section and adnexectomy: a case report and literature review T2 - J Int Med Res TI - Retained surgical needle and gauze after cesarean section and adnexectomy: a case report and literature review VL - 46 ID - 220 ER - TY - JOUR AN - 137199945. Language: English. Entry Date: 20190701. Revision Date: 20190701. Publication Type: Article AU - Steelman, Victoria M. DB - ccm DO - 10.1002/aorn.12740 DP - EBSCOhost IS - 1 KW - Retained Instruments -- Prevention and Control Patient Safety Perioperative Nursing Quality Assurance -- Methods Retained Instruments -- Complications Models, Theoretical Surgical Count Procedure Guideline Adherence Nursing Practice, Evidence-Based N1 - pictorial. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2019 SN - 0001-2092 SP - 92-96 ST - Retained Surgical Items: Evidence Review and Recommendations for Prevention T2 - AORN Journal TI - Retained Surgical Items: Evidence Review and Recommendations for Prevention UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=137199945&site=ehost-live&scope=site VL - 110 ID - 716 ER - TY - JOUR AB - BACKGROUND: Retained surgical items (RSI) continue to occur. Large RSI studies are few due to low RSI frequency in single institutions and the medicolegal implications. Consequently, RSI risks are not fully defined, with discrepancies persisting among published studies. The goals of this study were to better define risk factors for RSI, to clarify previously discrepant risk factors, and to evaluate other potential contributors to RSI occurrence, such as trainee presence during an operation. STUDY DESIGN: Multicenter case-match study of RSI risk factors was conducted between January 2003 and December 2009. Cases complicated by RSI were identified at participating centers using clinical quality improvement and adverse event reporting data. Case match controls (non-RSI) were selected from same or similar-type cases performed at each respective institution. Retained surgical item risk factors were evaluated by univariate and multivariate conditional logistic regression. RESULTS: Fifty-nine RSIs and 118 matched controls were analyzed (RSI incidence 1 in 6,975 or 59 in 411,526). Retained surgical items occurred despite use of confirmatory x-rays (13 of 27 instances) and/or radiofrequency tagging (2 of 32 instances). Among previously discrepant results, we confirmed that body mass index, unexpected intraoperative events, and procedure duration were associated with increased RSI risk. The occurrence of any safety variance, and specifically an incorrect count at any time during the procedure, was associated with elevated RSI risk. Trainee presence was associated with 70% lower RSI risk compared with trainee absence. CONCLUSIONS: Longer duration of surgery, safety variances, and incorrect counts during the procedure result in elevated RSI risk. The possible positive influence of trainee presence on RSI risk deserves additional study. Our findings highlight the need for zero tolerance for safety omissions, continued study and development of novel approaches to RSI reduction, and establishing anonymous RSI reporting systems to better track both the incidence and risks associated with this problem, which has yet to be solved. AD - Department of Surgery, The Ohio State University College of Medicine, Columbus, OH 43210, USA. stanislaw.stawicki@osumc.edu AN - 23041050 AU - Stawicki, S. P. AU - Moffatt-Bruce, S. D. AU - Ahmed, H. M. AU - Anderson, H. L., 3rd AU - Balija, T. M. AU - Bernescu, I. AU - Chan, L. AU - Chowayou, L. AU - Cipolla, J. AU - Coyle, S. M. AU - Gracias, V. H. AU - Gunter, O. L. AU - Marchigiani, R. AU - Martin, N. D. AU - Patel, J. AU - Seamon, M. J. AU - Vagedes, E. AU - Ellison, E. C. AU - Steinberg, S. M. AU - Cook, C. H. DA - Jan DO - 10.1016/j.jamcollsurg.2012.08.026 DP - NLM ET - 2012/10/09 IS - 1 KW - Adult Aged Body Mass Index Case-Control Studies Female Foreign Bodies/*etiology/prevention & control Humans Internship and Residency Intraoperative Complications Logistic Models Male Middle Aged Multivariate Analysis Operative Time Patient Safety Retrospective Studies Risk Factors *Surgical Instruments LA - eng N1 - 1879-1190 Stawicki, Stanislaw P A Moffatt-Bruce, Susan D Ahmed, Hesham M Anderson, Harry L 3rd Balija, Tara M Bernescu, Irina Chan, Liza Chowayou, Laurie Cipolla, James Coyle, Susette M Gracias, Vicente H Gunter, Oliver L Marchigiani, Raffaele Martin, Niels D Patel, Jigar Seamon, Mark J Vagedes, Eileen Ellison, E Christopher Steinberg, Steven M Cook, Charles H Evaluation Study Journal Article Multicenter Study United States J Am Coll Surg. 2013 Jan;216(1):15-22. doi: 10.1016/j.jamcollsurg.2012.08.026. Epub 2012 Oct 4. PY - 2013 SN - 1072-7515 SP - 15-22 ST - Retained surgical items: a problem yet to be solved T2 - J Am Coll Surg TI - Retained surgical items: a problem yet to be solved VL - 216 ID - 128 ER - TY - JOUR AB - Learning Objectives 1. Identify the names of surgical equipment seen on intraoperative and postoperative imaging. 2. Become familiar with the physical and radiographic appearance of various retained surgical items including sponges, needles, hemostats, and other surgical items. 3. Identify risk factors for retained surgical items. Background Retained surgical items (RSI) can have catastrophic consequences for patients and healthcare providers. The retention of surgical items may cause serious harm resulting in further medical intervention. Surgical teams frequently count needles, sponges, and instruments in order to reduce the risk of retained instruments. Despite this meticulous and regulated process, count discrepancies do occur. Radiologists are routinely consulted to assess for possible retained surgical instruments; however, many radiologists are unfamiliar with the various names and appearance of surgical instruments, sponges, and needles that maybe seen on perioperative radiographs. In radiology reports, surgical devices are rarely or vaguely commented upon. Familiarity with the physical and radiographic appearance of surgical instruments will allow for more effective detection of retained surgical items. Our exhibit will present photographs and radiographs of several retained surgical items and familiarize radiologists with the appearance of these objects as they carry serious patient care and medicolegal implications. Content Photographs with detailed descriptions and names of multiple surgical items will initially be presented and the radiopaque markers will be outlined. This will be complemented by the radiographic appearance of multiple surgical items using both live case examples and chest and body phantoms. Examples of surgical items include: tonsil sponges, FISH viscera retainers, bovie tips, laparotomy sponges, peanut sponges, forceps, towel clamp, trocars, etc. A selection of cases with key teaching points will be also presented. Additionally, risk factors for retained surgical items will also be discussed. Summary Recognition and familiarity with the names and appearance of various retained surgical items will allow more effective detection and prevention of unwanted surgical re-intervention and medicolegal consequences. AD - A. Gore, Radiology, Emory University Hospital, Atlanta, GA, United States AU - Gore, A. AU - Chien, L. C. AU - Joshi, G. AU - Graves, J. A. DB - Embase DO - 10.1007/s10140-018-1632-9 IS - 5 KW - adult conference abstract forceps human laparotomy sponge learning needle nomenclature nonhuman patient care peanut phantom photography radiologist radiology retained instrument risk factor surgery teaching thorax tonsil towel clip trocar viscera X ray film LA - English M3 - Conference Abstract N1 - L623946777 2018-09-24 PY - 2018 SN - 1438-1435 SP - 578 ST - Retained surgical items: A pictorial and radiographic approach T2 - Emergency Radiology TI - Retained surgical items: A pictorial and radiographic approach UR - https://www.embase.com/search/results?subaction=viewrecord&id=L623946777&from=export http://dx.doi.org/10.1007/s10140-018-1632-9 VL - 25 ID - 333 ER - TY - JOUR AB - This article focuses on successfully addressing retained surgical items (RSI) as the basis of medical malpractice complaints. Despite count policies, staff education, and adjunct technologies available to operating room staff, RSIs remain the number one reported sentinel event in the U.Ss. (Accreditation Insider, 2018) Reviewing an RSI case requires deep understanding of how, what, and why an item was lost or forgotten. Using a combination of personal case studies, in-depth research, and incisive guidance, the author presents the essentials every LNC requires to successfully address RSI cases. AD - Chair for the 2017 Forum in Portland, OR AN - 135299986. Language: English. Entry Date: 20190318. Revision Date: 20191121. Publication Type: Article AU - Flanagan, Mary DA - Spring2019 DB - ccm DP - EBSCOhost IS - 1 KW - Retained Instruments Foreign Bodies Malpractice -- Legislation and Jurisprudence Adverse Health Care Event -- Prevention and Control Intraoperative Care Surgical Sponges Surgical Count Procedure Perioperative Nursing Operating Room Personnel Communication Iatrogenic Disease -- Prevention and Control Hospital Policies Incident Reports Patient Safety N1 - pictorial. Journal Subset: Editorial Board Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 9507785. PY - 2019 SN - 1080-3297 SP - 34-37 ST - Retained Surgical Items (RSI) T2 - Journal of Legal Nurse Consulting TI - Retained Surgical Items (RSI) UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=135299986&site=ehost-live&scope=site VL - 30 ID - 706 ER - TY - JOUR AB - Introduction: Gossypiboma is a serious but uncommon complication of surgical interventions. Most case reports and reviews refer to abdominal or thoracic surgery. Retained postoperative foreign bodies in limb or spine surgery are less commonly encountered. We present a case of gossypiboma in a paraplegic patient originating from pararectal surgery and detected 15 years after index surgery for infectious migration to the left thigh. Methods: We present an unusual clinical case and performed a systematic literature review on the subject. Case presentation: A 56-year-old paraplegic patient with complete sensory deficit in both legs presented with signs of an infected haematoma at the left thigh. At the time of surgical evacuation cotton tissue originating from a surgical gauze swab was retrieved. After a thorough investigation of the patient's medical history, polytrauma treatment consisting of emergent laparotomy with abdominal gauze packing in 1986 and surgical treatment of a fistulating pararectal abscess in 2001 were stated possible origins of the intraoperative findings. Further surgical interventions with a more extended approach were necessary. Another gauze tissue conglomerate was found next to the ischial tuberosity, revealing the surgical treatment of a pararectal abscess (developed from sacral decubiti) as the origin of the retained gauze swabs. Conclusion: Retained surgical gauze (RSG) swab is a serious and, due to medicolegal reasons, underreported complication of surgical intervention. Diagnosis can be challenging because patients may present with only vague symptoms. In the presented case the patient remained asymptomatic for 15 years, mainly due to his paraplegia. Prevention of RSG is far more important than cure. Awareness of the problem, staff training and the use of preventive measures as radiopaque labelled gauze swabs or monitored counting should be mandatory in every surgical intervention. AD - R. Vogel, Kantonsspital St. Gallen KSSG, Switzerland AU - Vogel, R. AU - Ladurner, A. AU - Rudin, D. DB - Embase KW - abscess adult awareness cell migration complication conference abstract cotton fistula foreign body hematoma human human tissue ischial tuberosity laparotomy male medical history middle aged multiple trauma paraplegia sensory dysfunction staff training surgery surgical swab systematic review thigh LA - English M3 - Conference Abstract N1 - L626846662 2019-03-26 PY - 2017 SN - 1424-3997 SP - 66S ST - Retained surgical gauze swab migration in a paraplegic patient: A case report and literature review T2 - Swiss Medical Weekly TI - Retained surgical gauze swab migration in a paraplegic patient: A case report and literature review UR - https://www.embase.com/search/results?subaction=viewrecord&id=L626846662&from=export VL - 147 ID - 377 ER - TY - JOUR AB - Objectives: To determine the frequency and modes of presentation of retained surgical foreign bodies. Methodology: This study was carried out mainly at a private teaching hospital i.e. Isra University Hospital and four other non-teaching private hospitals of Hyderabad city over a period of five years from June 2004 to May 2009. Results: A total of 15 patients with retained surgical foreign body were found during the above mentioned study period. Female patients were more common than male patients. Gynaecological procedures were more frequently associated with surgical retained foreign bodies. Most (60%) of the causative procedures were performed as emergency procedures. Retained sponge was the most frequent foreign body (60%) followed by gauze piece. Discharging sinuses and abdominal masses (33.3% each) were the most frequent presentations followed by intestinal obstruction (20%). Conclusion: Retained surgical foreign body is a rare but well known iatrogenic complication of surgery mostly seen in procedures done as emergency. Discharging sinuses, abdominal mass and intestinal obstruction are the most common modes of presentation. Proper frequent double sponge count and use of radioopaque markers are the major preventive measures to safeguard against this dangerous complication. AD - T. W. Khanzada, C- 51, Husnain Square, Liberty Market, Jacob Road, Hyderabad 71000, Pakistan AU - Sushel, C. AU - Khanzada, T. W. AU - Samad, A. DB - Embase IS - 1 KW - abdominal mass adult article child clinical article female foreign body gauze dressing human intestine obstruction male school child surgical foreign body teaching hospital L1 - internal-pdf://0304089172/article04.pdf LA - English M3 - Article N1 - L358308632 2010-02-24 2010-04-19 PY - 2010 SN - 1682-024X SP - 15-20 ST - Retained surgical foreign bodies: Can these be prevented? T2 - Pakistan Journal of Medical Sciences TI - Retained surgical foreign bodies: Can these be prevented? UR - https://www.embase.com/search/results?subaction=viewrecord&id=L358308632&from=export VL - 26 ID - 573 ER - TY - JOUR AB - BACKGROUND: Retained abdominal sponge after surgery is a quite rare condition which can have heavy medico-legal consequences; its frequency is generally underestimated. Few reports of these conditions are available in African environment with specific technical and medico-legal background. We present our local experience of retained sponges after abdominal surgery and review current literature. METHOD: A retrospective analysis of the medical files of 14 consecutive patients with a retained surgical sponge after abdominal and urological surgery. RESULTS: The incidence was 1every 677 abdominal operations; no metallic foreign body described, only sponges; the female sex predominated with 10/14 patients. 85.71% of retained sponge occurred after an emergency procedure and 64.28% were gynecological or obstetrical procedures. Most cases presented as intestinal obstruction, localized persistent pain or abdominal mass and pre-operative diagnosis could be done only in 28.57% of cases. A falsely correct sponge count was reported in 71.42% of cases 92.85% of patients were re-operated and the morbidity was low; no death was reported. None of our cases ended in a medico-legal claim despite proper counseling. CONCLUSION: The incidence of retained sponge might be significantly higher in an environment with reduced medico-legal threat; most cases of retained sponges are still related to human errors; the incidence will probably be reduced by a greater awareness about the condition. AD - Faculty of health sciences, University of Buéa and regional hospital, Limbé, Cameroon. AN - 21532906 AU - Mefire, A. C. AU - Tchounzou, R. AU - Guifo, M. L. AU - Fokou, M. AU - Pagbe, J. J. AU - Essomba, A. AU - Malonga, E. E. C2 - PMC2984279 DA - Jul 5 DP - NLM ET - 2009/01/01 KW - abdomina gossypiboma LA - eng N1 - 1937-8688 Mefire, Alain Chichom Tchounzou, Robert Guifo, Marc Leroy Fokou, Marcus Pagbe, Jean Jacques Essomba, Arthur Malonga, Eimo Elisée Journal Article Pan Afr Med J. 2009 Jul 5;2:10. PY - 2009 SN - 1937-8688 (Print) SP - 10 ST - Retained sponge after abdominal surgery: experience from a third world country T2 - Pan Afr Med J TI - Retained sponge after abdominal surgery: experience from a third world country VL - 2 ID - 85 ER - TY - JOUR AB - We present an unusual case of a retained resectoscope beak detected 10 months following transurethral resection of a bladder tumour. We describe this rare complication after transurethral surgery and present a safe method for removing a resectoscope beak from the urethra. This case prompted several improvements in our local surgical checklists to prevent such an event from recurring. It is important to check the integrity of surgical equipment in addition to counting equipment in and out during theatre; without checking, as exemplified by the resectoscope in this case, we risk missing the point. AD - C. Lockett, Department of Urology, Peterborough City Hospital, Bretton Gate, Peterborough, United Kingdom AU - Smith, S. F. AU - Miakhil, S. I. AU - Johnston, T. J. AU - Lockett, C. DB - Embase DO - 10.1177/2051415816670817 IS - 1 KW - adult article bladder tumor case report cystectomy cystoscope cystoscopy device removal forceps foreign body human male middle aged resectoscope retained instrument urethra obstruction LA - English M3 - Article N1 - L614101360 2017-01-23 2017-02-03 PY - 2017 SN - 2051-4166 2051-4158 SP - 56-57 ST - A retained resectoscope beak: are we missing the point of surgical checklists? T2 - Journal of Clinical Urology TI - A retained resectoscope beak: are we missing the point of surgical checklists? UR - https://www.embase.com/search/results?subaction=viewrecord&id=L614101360&from=export http://dx.doi.org/10.1177/2051415816670817 VL - 10 ID - 382 ER - TY - JOUR AB - Purpose: To report a case of a mixed open globe injury in which a retained large iron nail and perforating injury of the eye coexisted. Methods: Case report. Results: A 26-year-old construction worker was injured by a nail while using a nail gun at work. The iron nail was inadvertently stabbed into the left eye from the upper eyelid and superonasal sclera to temporal sclera, with lens involvement. His visual acuity was counting fingers in the left eye. Primary suture, removal of a retained iron nail, pars plana vitrectomy and lensectomy, and laser photocoagulation were performed. Three months later, an intraocular lens was implanted in the ciliary sulcus. During postoperative 6-month follow-up, final best-corrected visual acuity was 20/20 without complication. Conclusion: We describe one patient with a mixed open globe injury of a retained nail and perforating injury of the eye resulting from a nail gun. As most eye injuries are preventable, proper training of nail-gun operators and use of safety equipment could reduce the incidence of ocular injuries. Expeditious removal of nails and repair of the lacerations can prevent the complications and achieve good final visual outcomes. © Springer-Verlag 2007. AD - Department of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5 Fu-Hsing Street, Kwei-Shan, Taoyuan 333, Taiwan Department of Ophthalmology, Chang Gung Memorial Hospital, 5 Fu-Hsing Street, Kwei-Shan, Taoyuan 333, Taiwan AU - Chen, K. J. AU - Sun, M. H. AU - Hou, C. H. AU - Chen, T. L. DB - Scopus DO - 10.1007/s00417-007-0613-6 IS - 2 KW - Intraocular foreign body Nailgun injury Perforation injury M3 - Article N1 - Cited By :8 Export Date: 10 November 2020 PY - 2008 SP - 213-215 ST - Retained large nail with perforating injury of the eye T2 - Graefe's Archive for Clinical and Experimental Ophthalmology TI - Retained large nail with perforating injury of the eye UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-38549171356&doi=10.1007%2fs00417-007-0613-6&partnerID=40&md5=ae082b5783044cf68e5647a96b6eb6f9 VL - 246 ID - 1537 ER - TY - JOUR AB - A 72-year-old man had exchange of a foldable silicone multifocal intraocular lens (IOL) by transection, removal, and monofocal IOL replacement. One month after the exchange, irreversible corneal edema developed and penetrating keratoplasty was performed. At the time of the corneal transplant, a small silicone fragment was discovered in and removed from the anterior chamber. Histologic evaluation of the patient's cornea demonstrated an absence of corneal endothelium, suggesting the fragment was the etiology of the corneal decompensation. © 2004 ASCRS and ESCRS. AD - 1550 Oak Street, Eugene, OR 97401, United States AU - Hoffman, R. S. AU - Fine, I. H. AU - Packer, M. DB - Scopus DO - 10.1016/j.jcrs.2003.08.015 IS - 6 M3 - Article N1 - Cited By :8 Export Date: 10 November 2020 PY - 2004 SP - 1362-1365 ST - Retained IOL fragment and corneal decompensation after pseudophakic IOL exchange T2 - Journal of Cataract and Refractive Surgery TI - Retained IOL fragment and corneal decompensation after pseudophakic IOL exchange UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-2942527536&doi=10.1016%2fj.jcrs.2003.08.015&partnerID=40&md5=6ebaa7efadd319477830c751b534d3e0 VL - 30 ID - 1627 ER - TY - JOUR AB - Introduction. Gossypiboma or textiloma is used to describe a retained surgical swab in the body after an operation. Intraabdominal surgical sponge is an uncommon surgical error. The incidence of gossypiboma has been reported as high as 1 in 1000 to 15,000 intraabdominal operations. Gossypiboma may cause serious morbidity and may lead to mortality. Case presentation. Herein, we report a 24 years-old man who was admitted due to the intraabdominal mass after evaluation of primary infertility. He had a surgical history of bilateral abdominal orchiopexy 5 years previously, performed at another hospital. Hydatid cyst was suspected by abdominal computed tomography. After laparotomy excision, the cyst wall opened incidentally, and draining of a large amount of thick pus with retained surgical gauze within the cyst was found, with final diagnosis of gossypiboma. Conclusion. The policy that prevention is far more important than cure is highly appreciated. Accurate sponge and instrument counts, along with radiologic evaluation when a discrepancy is found, can be helpful. Although human errors cannot be completely avoided, continuous medical training and strict adherence to rules of the operation room should reduce the incidence of gossypiboma to a minimum. Surgical sponges should be counted once at the start and twice at the end of all surgical operations. AD - Urology Division, Kamkar Hospital, School of Medicine, Qom Medical Sciences University, 3715694978 Qom, Iran. AN - 20224652 AU - Moslemi, M. K. AU - Abedinzadeh, M. C2 - PMC2833312 DO - 10.1155/2010/420357 DP - NLM ET - 2010/03/13 LA - eng N1 - 1687-9635 Moslemi, Mohammad Kazem Abedinzadeh, Mehdi Case Reports Case Rep Med. 2010;2010:420357. doi: 10.1155/2010/420357. Epub 2010 Mar 4. PY - 2010 SN - 1687-9627 (Print) SP - 420357 ST - Retained intraabdominal gossypiboma, five years after bilateral orchiopexy T2 - Case Rep Med TI - Retained intraabdominal gossypiboma, five years after bilateral orchiopexy VL - 2010 ID - 97 ER - TY - JOUR AB - Introduction: Gossypiboma is used to describe a retained surgical swab in the body after an operation. Intra-abdominal surgical sponge is an uncommon surgical error. Among retained foreign bodies, a surgical gauze or sponge constitutes the most frequently encountered object because of its common usage, small size and amorphous structure. Gossypiboma may cause serious morbidity and may lead to mortality. Case Report: A 32 year old woman presented with a week history of lower back pain and suprapubic pain associated with whitish vaginal discharge. Vaginal examination revealed caseous discharge around an open cervix, with a bulky uterus and a solitary firm mass posterior to the uterus measuring 4 × 5 cm. An initial impression of cystic torsion with adhesion was made. Previous surgical procedures were performed at another medical facility in 2000. An exploratory laparatomy for left sided adnexal mass was performed about 1 year after the initial presentation. Intraoperative findings yielded numerous adhesions and a walled gauze measuring 5 × 5 × 4 cm. The histological diagnosis was in keeping with Gossypiboma and chronic granulomatous inflammation. The patient responded well to post operative management. Conclusion: The policy that prevention is better than cure is highly appreciated. Accurate sponge and instrument counts, with radiologic evaluation when a discrepancy is found, can be helpful. Although human errors cannot be completely avoided, continuous medical training and strict adherence to rules of the operation room should reduce the incidence of gossypiboma to a minimum. AD - E.O. Umobong, Department of Laboratory Medicine, State House Medical Center, Asokoro, Abuja, Nigeria AU - Umobong, E. O. AU - Ibrahim, I. O. AU - Ezemamma, J. C. AU - Taiwo, K. E. DB - Embase DO - 10.1111/j.1365-2559.2012.04359-11.x KW - pathology human adhesion uterus surgical error foreign body surgical sponge mortality histology patient case report female vagina discharge morbidity pain pelvic examination low back pain torsion surgical technique granulomatous inflammation policy prevention error medical education operating room surgical swab LA - English M3 - Conference Abstract N1 - L70934372 2012-12-11 PY - 2012 SN - 0309-0167 SP - 112-113 ST - Retained intraabdominal gossypiboma 12 years after laparatomy T2 - Histopathology TI - Retained intraabdominal gossypiboma 12 years after laparatomy UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70934372&from=export http://dx.doi.org/10.1111/j.1365-2559.2012.04359-11.x VL - 61 ID - 505 ER - TY - JOUR AB - Cases of retained foreign body are rarely reported due to its medico-legal implications. We present a case of retained surgical gauze fragments after bipolar hemiarthroplasty of hip in a patient who sustained left neck of femur fracture. This complication occurred despite strict adherence to standard operating theater protocols which includes meticulous swab and instrument count. We propose an additional operating room processes and surgical technique in preventing such complications in future hip arthroplasties in our centre. AD - Department of Orthopaedics and Traumatology, Hospital Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia AN - 131781319. Language: English. Entry Date: 20180921. Revision Date: 20180921. Publication Type: Article AU - Wui, N. G. Bing AU - Mohd Ariff, Mohamed Ashraff AU - Abdul Rani, Rizal AU - Mohd Yahaya, Nor Hamdan DB - ccm DP - EBSCOhost IS - 6 KW - Arthroplasty, Replacement, Hip -- Methods Bandages and Dressings Foreign Bodies Postoperative Complications Postoperative Period Hip Fractures Protocols Surgical Count Procedure Operating Rooms Hemiarthroplasty -- Methods Female Aged N1 - case study; diagnostic images; pictorial. Journal Subset: Biomedical; Middle East. PY - 2017 SN - 1560-5876 SP - 207-210 ST - Retained Fragment of Surgical Gauze in Hip Arthroplasty - Case Report and Literature Review T2 - Brunei International Medical Journal (BIMJ) TI - Retained Fragment of Surgical Gauze in Hip Arthroplasty - Case Report and Literature Review UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131781319&site=ehost-live&scope=site VL - 13 ID - 721 ER - TY - JOUR AB - Retained foreign bodies remain an area of potential patient harm. This case describes a retained needle from distant surgery discovered at the time of the needle count after myomectomy. AD - From the *Department of Obstetrics and Gynecology, KU School of Medicine-Wichita, Wichita, Kansas; †Departments of Basic Biomedical Sciences and Obstetrics and Gynecology, and ‡Department of Obstetrics and Gynecology, Sanford School of Medicine of the University of South Dakota, South Dakota. AN - 24522211 AU - O'Brien, L. AU - Eyster, K. M. AU - Hansen, K. A. DA - Dec DO - 10.1097/pts.0000000000000078 DP - NLM ET - 2014/02/14 IS - 4 KW - Adult Female Foreign Bodies/*etiology/mortality General Surgery Humans Medical Errors/*statistics & numerical data Needles Risk Factors Surgical Instruments LA - eng N1 - 1549-8425 O'Brien, Lauren Eyster, Kathleen M Hansen, Keith A Case Reports Journal Article United States J Patient Saf. 2015 Dec;11(4):228-9. doi: 10.1097/PTS.0000000000000078. PY - 2015 SN - 1549-8417 SP - 228-9 ST - Retained Foreign Body: "Needle in a Haystack" T2 - J Patient Saf TI - Retained Foreign Body: "Needle in a Haystack" VL - 11 ID - 148 ER - TY - JOUR AB - Liver transplantation is a technically complex and long surgical procedure. A large quantity of various materials such as catheters, sutures, needles and clips are frequently used during the procedure. These materials may enter in the liver from the vascular or biliary orifices inadvertently. A 50-year-old patient who had hepatic failure due to HBV underwent a deceased-donor liver transplantation. The deceased donor was a 75-year-old HbsAg+ man. The recipient had subfebrile fever and leukocytosis post-operatively. A control computed tomography revealed a cuneiform ischemic area, and a foreign body inside the right anterior portal vein branch proximal to this ischemic region. A 10-F Nelaton catheter, 5-cm long, was removed from the portal vein by surgery. Retrospectively, we understood that the portal vein was cut during the backtable procedure and the portal vein catheter was replaced with a larger one for better irrigation. Most probably, the original catheter was cut together with the portal vein, and the tip of the catheter was retained in the portal system and migrated into the liver. As far as we know, such a complication of liver transplantation has never been described previously. AD - Inonu University, Liver Transplantation Institute, Malatya, Turkey AU - Kayaalp, C. AU - Kirmizi, S. AU - Kutlu, R. AU - Yagci, M. A. AU - Isik, B. AU - Yilmaz, S. DB - Scopus IS - 4 KW - Foreign body Liver transplantation Portal vein Post-operative complication M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2015 SP - 185-187 ST - Retained foreign body in transplanted liver T2 - International Journal of Organ Transplantation Medicine TI - Retained foreign body in transplanted liver UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84944905261&partnerID=40&md5=976e34d4203de8a334bdbbec3c45132c VL - 6 ID - 1237 ER - TY - JOUR AB - Retained foreign bodies sometimes occur in various surgical procedures and can lead to severe complications. Foreign bodies in the oral and maxillofacial region are not rare because of the use of many small items and the natural communication with the outside environment in some areas. We experienced a case of foreign body in the nasal cavity, which was discovered 1 year later at a second operation for hardware removal after maxillofacial surgery. A small, soft material is usually placed between the nasal endotracheal tube and nostril to avoid nasal pressure ulcer at the ala of nose after prolonged anesthesia after our group's experiencing some cases of this complication. The foreign body was found in the pharynx during induction of a second anesthesia. Attention should be directed to not leaving any materials in the patient after surgery. In addition to the normal counts of sponges, needles, etc, other small nonsurgical materials used should be recorded by medical staff to help ensure nothing is retained in the patient. AD - Department of Dental Anesthesiology, Kyushu University Hospital, Fukuoka, Japan, and. Department of Dental Anesthesiology, Faculty of Dental Science, Kyushu University, Fukuoka, Japan. AN - 29952650 AU - Tsukamoto, M. AU - Hirokawa, J. AU - Yokoyama, T. C2 - PMC6022801 DA - Summer DO - 10.2344/anpr-65-01-07 DP - NLM ET - 2018/06/29 IS - 2 KW - Foreign Bodies/diagnosis/*etiology/surgery Humans Male Malocclusion, Angle Class III/*surgery Mandibular Osteotomy/*adverse effects *Nasal Cavity/surgery Osteotomy, Le Fort/*adverse effects Reoperation Treatment Outcome Young Adult *Foreign body *General anesthesia *Nose *Oral surgery LA - eng N1 - 1878-7177 Tsukamoto, Masanori Hirokawa, Jun Yokoyama, Takeshi Case Reports Journal Article Anesth Prog. 2018 Summer;65(2):111-112. doi: 10.2344/anpr-65-01-07. PY - 2018 SN - 0003-3006 (Print) 0003-3006 SP - 111-112 ST - Retained Foreign Body in the Nasal Cavity After Oral Maxillofacial Surgery T2 - Anesth Prog TI - Retained Foreign Body in the Nasal Cavity After Oral Maxillofacial Surgery VL - 65 ID - 215 ER - TY - JOUR AB - Objectives: To review risk factors and complications associated with retained foreign bodies in surgical patients. Materials and Methods: Retrospective review of medical records and litigation claims at Detroit Medical Center between 1998 and 2010. Chi square test and logistic regression were used for analysis. Results: There were a total of 67 patients who had 70 retained foreign bodies. These included 26 sponges (37.1%), 12 drains and catheters (17.1%), 6 instruments (8.5%), 3 needles (4.2%), 3 packings (4.2%) and 20 miscellaneous (including one resected bowel loop). Median age was 51years (range 1 day - 95 years), median BMI was 31.03 kg/m 2. Abdomen (35.7%) and thorax (12.8%) were the most commonly involved body cavities. Most common reason for search for foreign body was pain (27.5%). Median latency time of detection was 84 days (range 0 days - 14 years). Sponge count was available in 68.9% of the cases. Primary count was incorrect in 30% of the cases where a count was available. The common risk factors identified in the operative cases with retained foreign bodies were torrential bleeding(63.6%), extensive adhesions(36.3%), 91 surgical team(27.2%) and intra-op change of procedure(18%). Of these cases, 34.4% were emergency surgeries. Morbidity rate was 100% as all the patients required reoperation for removal of foreign body. Associated complications included fever, ileus, abscess, wound infection, acute ischemia and delayed recovery. There were no deaths. Conclusion: Retained surgical foreign body is a persistent medical error with severe complications. The surgeon should be cognizant of this possibility, especially in cases complicated by obesity, emergency situations, bleeding, adhesions and change of surgical teams or procedures. AD - M. Thakur, Department of Obstetrics and Gynecology, Detroit Medical Center, Wayne State University, Detroit, MI, United States AU - Thakur, M. AU - Kumar, S. AU - Gill, N. AU - Bahado-Singh, R. O. DB - Embase DO - 10.1097/SPV.0b013e31820e8a9a IS - 2 KW - foreign body surgeon society bleeding risk factor human patient adhesion emergency surgery morbidity reoperation fever ileus abscess wound infection ischemia death medical error obesity emergency surgical patient medical record chi square test logistic regression analysis catheter needle intestine abdomen thorax pain latent period law suit LA - English M3 - Conference Abstract N1 - L70485186 2011-08-04 PY - 2011 SN - 1542-5983 SP - S40 ST - Retained foreign body in surgical setting: A single center experience T2 - Journal of Pelvic Medicine and Surgery TI - Retained foreign body in surgical setting: A single center experience UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70485186&from=export http://dx.doi.org/10.1097/SPV.0b013e31820e8a9a VL - 17 ID - 546 ER - TY - JOUR AB - Foreign bodies may occur after a thoracic trauma, but foreign bodies retained after stab wounds are rare. This paper reports the case of a 20-year-old man who was admitted with the diagnosis of haemothorax following a single stab wound on the chest. One month later, he was referred to the authors' clinic with symptoms of pain and swelling under the left scapula due to a previously overlooked foreign body on the chest wall. Copyright 2014 BMJ Publishing Group. All rights reserved. AD - Department of Thoracic Surgery, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey Department of Thoracic Surgery, Konya Education and Research Hospital, Konya, Turkey Department of Pulmonary Medicine, Konya Education and Research Hospital, Konya, Turkey AU - Apiliogullari, B. AU - Duzgun, N. AU - Kurtipek, E. AU - Esme, H. DB - Scopus DO - 10.1136/bcr-2014-203598 M3 - Article N1 - Export Date: 10 November 2020 PY - 2014 ST - Retained foreign body after chest stab wound T2 - BMJ Case Reports TI - Retained foreign body after chest stab wound UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84897139430&doi=10.1136%2fbcr-2014-203598&partnerID=40&md5=6175c31b39b2ba2cef845e819ac76843 ID - 1262 ER - TY - JOUR AB - Retained foreign bodies (RFBs) are a surgical complication resulting from foreign materials accidently left in a patient's body. This review attempts to give an overview of different types of RFBs, problems related to them and their management after the surgical operation. The internet was searched using the Google and Google scholar. In addition, relevant electronic journals from the University's library such as Entrez (including PubMed and PubMed central), Since Direct, Scirus, NIH.gov, Medknow.com, Medscape.com, Scopus, MedHelp.org, Cochrane library, WebMD.com, and World Health Organization Hinari. It shows that the major reasons of RFBs are emergency surgical operation with unplanned changes, patient high body mass index, and poor communication. To prevent this textile material should be radiopaque marked and must be counted once at the start and twice at the conclusion of all surgical procedures. If the count is incorrect, then radiography or manually re-exploration should be performed. Ultrasonography, computerized tomography, magnetic resonance imaging and radio frequency identification are also used in the proper identification of RFBs. Safety practice should be robust and simple enough to protect patient under the most chaotic of circumstances. Proper communication among the personnel participating in surgery aimed at preventing this medical negligence would help in mitigating such errors. Finally, the surgeon should not only follow the standard recommended procedure, but also report cases of RFBs. AD - Department of Biomedical and Pharmaceutical Science, College of Pharmacy, Idaho State University, Pocatello, Idaho, USA. AN - 24669327 AU - Sharma, G. AU - Bigelow, J. C2 - PMC3952293 DA - Jan DO - 10.4103/2141-9248.126605 DP - NLM ET - 2014/03/29 IS - 1 KW - Medical negligence Radiography Retained foreign bodies LA - eng N1 - 2277-9205 Sharma, G Bigelow, Jc Journal Article Review Ann Med Health Sci Res. 2014 Jan;4(1):30-7. doi: 10.4103/2141-9248.126605. PY - 2014 SN - 2141-9248 (Print) 2141-9248 SP - 30-7 ST - Retained foreign bodies: a serious threat in the Indian operation room T2 - Ann Med Health Sci Res TI - Retained foreign bodies: a serious threat in the Indian operation room VL - 4 ID - 149 ER - TY - JOUR AB - BACKGROUND: Medical errors during surgery are not well studied. To define risk factors associated with this type of error, we performed a case control analysis. METHODS: We retrospectively reviewed medical records involving the ICD-9 code (998.4) for unintentional foreign object remaining in the body during surgery and incident reports gathered by the Department of Risk Management over a 10 year period from 1996 to 2005. Thirty cases were matched with at least four randomly selected controls (131 control patients) that underwent the same type of operation during the same time period. RESULTS: Thirty patients had retained foreign objects (52% sponges and 43% instruments). The abdominal cavity was most commonly involved (46%) followed by the thoracic cavity (23%) although no body cavity remained uninvolved. Eight patients required readmission (30%), 25 patients required reoperation (83%), and there was no mortality. When compared with controls, patients with retained foreign objects were more likely to have had a greater number of major surgical procedures at the same time (2.7 versus 1.8, P=0.004), to have multiple surgical teams (13% versus 2%, P=0.02), and more likely to have had an incorrect instrument/sponge count recorded (13% versus 2%, P=0.01). In multivariate analysis, factors associated with a significantly higher risk of retained foreign objects were the total number of major procedures performed [odds ratio 1.6; 95% confidence interval (CI), 1.1-2.3; P=0.008] and an incorrect count (odds ratio 16.2; 95% CI, 1.3-197.8; P=0.02). CONCLUSION: Retained foreign objects after surgery are associated with multiple major surgical procedures being performed at the same time and an incorrect instrument or sponge count. Identification of these risk factors using case-control analysis should influence operating room policy and reduce these types of errors. AD - Department of General Surgery, Carolinas Medical Center, Charlotte, North Carolina 28203, USA. AN - 17275034 AU - Lincourt, A. E. AU - Harrell, A. AU - Cristiano, J. AU - Sechrist, C. AU - Kercher, K. AU - Heniford, B. T. DA - Apr DO - 10.1016/j.jss.2006.08.001 DP - NLM ET - 2007/02/06 IS - 2 KW - Adult Case-Control Studies Female Foreign Bodies/*epidemiology Humans Incidence Male Medical Errors/*statistics & numerical data Middle Aged Multivariate Analysis Postoperative Complications/*epidemiology Reoperation/statistics & numerical data Retrospective Studies Risk Factors Risk Management Surgical Instruments/statistics & numerical data Surgical Sponges/statistics & numerical data LA - eng N1 - Lincourt, Amy E Harrell, Andrew Cristiano, Joseph Sechrist, Cathy Kercher, Kent Heniford, B Todd Journal Article United States J Surg Res. 2007 Apr;138(2):170-4. doi: 10.1016/j.jss.2006.08.001. Epub 2007 Feb 1. PY - 2007 SN - 0022-4804 (Print) 0022-4804 SP - 170-4 ST - Retained foreign bodies after surgery T2 - J Surg Res TI - Retained foreign bodies after surgery VL - 138 ID - 64 ER - TY - JOUR AB - Trauma patients are thought to be at high risk for iatrogenic retained foreign bodies (RFBs). The objective of this study was to evaluate this incidence. All cases of RFB after cavitary trauma surgery were identified by review of Morbidity and Mortality reports at a Level 1 trauma center from January 1998 to December 2005 and confirmed by the Octagon Risk Management System. Over 8 years, 10,053 trauma operations were performed (2075 laparotomies, 377 thoracotomies, and 74 sternotomies). Three cases (0.1%) of RFB (all sponges) occurred during one single-stage and two damage control laparotomies. The counts were correct before definitive closure in two of three cases. No postoperative x-rays were obtained in any of the cases. RFB diagnosis occurred between days 3 and 9, one on a routine chest x-ray and the other two on abdominal computed tomography scans during a septic workup. Four-month to 8-year follow up documented one pleural effusion and one abscess resulting from the RFB. Iatrogenic RFBs after emergent cavitary trauma surgery occur at a rate of 0.12 per cent and are associated with significant morbidity. In addition to standard preventive strategies, in emergent cases with risk factors such as requiring damage control, before final cavity closure, even with a correct sponge count, radiographic evaluation is warranted. AD - Division of Trauma Surgery and Surgical Critical Care, University of Southern California, USC+LAC Medical Center, Los Angeles, California 90033, USA. AN - 17983075 AU - Teixeira, P. G. AU - Inaba, K. AU - Salim, A. AU - Brown, C. AU - Rhee, P. AU - Browder, T. AU - Belzberg, H. AU - Demetriades, D. DA - Oct DP - NLM ET - 2007/11/07 IS - 10 KW - Adult Emergency Treatment Foreign Bodies/complications/diagnosis/*epidemiology Humans Iatrogenic Disease/*epidemiology Intraoperative Complications/*epidemiology *Laparotomy Sternum/surgery *Surgical Sponges *Thoracotomy Tomography, X-Ray Computed LA - eng N1 - Teixeira, Pedro G R Inaba, Kenji Salim, Ali Brown, Carlos Rhee, Peter Browder, Timothy Belzberg, Howard Demetriades, Demetrios Journal Article United States Am Surg. 2007 Oct;73(10):1031-4. PY - 2007 SN - 0003-1348 (Print) 0003-1348 SP - 1031-4 ST - Retained foreign bodies after emergent trauma surgery: incidence after 2526 cavitary explorations T2 - Am Surg TI - Retained foreign bodies after emergent trauma surgery: incidence after 2526 cavitary explorations VL - 73 ID - 70 ER - TY - JOUR AB - Six cases of retained foreign bodies [sternal wire, two pieces of catheters, sponge (surgical gauze), surgical towel, and an instrument] after cardiovascular surgery are presented. All six cases were submitted to the north German arbitration board with the reproach of medical malpractice. In four cases, the allegations were found to be true. How often foreign bodies are forgotten and how retainment may be prevented by count control are discussed using data from a literature search. © 2010 Springer-Verlag. AD - Schlichtungsstelle für Arzthaftpflichtfragen der Norddeutschen Ärztekammern, Hans-Böckler-Allee 3, 30173 Hannover, Germany AU - Leitz, K. H. AU - Neu, J. DB - Scopus DO - 10.1007/s00398-010-0804-z IS - 6 KW - Compensation Count control Foreign bodies Malpractice Surgical sponges M3 - Article N1 - Export Date: 10 November 2020 PY - 2010 SP - 364-368 ST - Zurückgelassene Fremdkörper nach kardiovaskulärer Chirurgie T2 - Zeitschrift fur Herz-, Thorax- und Gefasschirurgie TI - Retained foreign bodies after cardiovascular surgery UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-78751640573&doi=10.1007%2fs00398-010-0804-z&partnerID=40&md5=698c7b6ce6aed65b151e1febfe160d4a VL - 24 ID - 1446 ER - TY - JOUR AB - Background and Objectives: To look into clinical presentations of intra-abdominal foreign bodies, identify risk factors for incorrect sponge and towel counts. Describe complications that can occur from retained sponges and towels, to see measures for prevention. Patient and method: The records of twelve patients with a confirmed diagnosis of gossypiboma after abdominal surgery at AL - Kadhimyia teaching hospital and private hospital, in Baghdad, between January 2007 and January 2010, were retrospectively reviewed Results: Nine of the twelve patients were female and three male. Previously, of the patients, three underwent elective operations and nine were operated on for emergency. Among retained surgical foreign bodies, sponges accounted for 66.6% of patients, gauze were found in 33.3% of patients.. Operated in emergency 75% and elective 25%. Clinical presentations were intestinal obstruction 25%., abdomen Mass 25%, Discharging Sinus 16.6%, Intra abdominal abscessl6.6%, Persistent abdominal pain 16.6%. Conclusions: Retained foreign bodies commonly occur during an emergent procedure when the surgical team's efforts are completely focused on saving the patient's life. In that scenario, speed is essential and taking the time to perform a surgical count may not be an option. Other situations or factors that may lead to a retained foreign body include unplanned changes in the surgical procedure, patients with increased body mass, and procedures involving increased blood loss. AD - Department of Surgery, Al-Nahrain Medical College, Al-Kadhimyia Teaching Hospital, Baghdad, Iraq AU - Ahmed, H. A. H. DB - Scopus IS - 3 KW - Gossypiboma Retained abdominal M3 - Article N1 - Export Date: 10 November 2020 PY - 2010 SP - 41-46 ST - Retained foreign bodies after abdominal surgery T2 - New Iraqi Journal of Medicine TI - Retained foreign bodies after abdominal surgery UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79958151968&partnerID=40&md5=b2d6339aff0b3e54c7c17d04b2d82ad2 VL - 6 ID - 1440 ER - TY - JOUR AN - 106452790. Language: English. Entry Date: 20060609. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 1 KW - Endoscopes Endoscopy, Gastrointestinal Stents Surgical Count Procedure Sterilization and Disinfection N1 - brief item. Journal Subset: Australia & New Zealand; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. PY - 2006 SN - 1444-027X SP - 11-11 ST - Retained biliary stent within a duodenoscope...Reprinted from TGA news. Issue 48. November 2005 T2 - J.GENCA TI - Retained biliary stent within a duodenoscope...Reprinted from TGA news. Issue 48. November 2005 UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106452790&site=ehost-live&scope=site VL - 16 ID - 937 ER - TY - JOUR AB - PURPOSE: To evaluate the uveal and capsular biocompatibility of hydrophilic acrylic, hydrophobic acrylic, and silicone intraocular lenses (IOLs) in eyes with uveitis. SETTING: Department of Ophthalmology, University of Vienna, Vienna, Austria. METHODS: This prospective study comprised 72 eyes with uveitis and 68 control eyes having phacoemulsification and IOL implantation by 1 surgeon. Patients received 1 of the following IOLs: foldable hydrophilic acrylic (Hydroview, Bausch & Lomb), hydrophobic acrylic (AcrySof, Alcon), or silicone (CeeOn 911, Pharmacia). Postoperative evaluations were at 1, 3, and 7 days and 1, 3, and 6 months. Cell reaction was evaluated by specular microscopy of the anterior IOL surface and the anterior and posterior capsule reaction, by biomicroscopy. RESULTS: Small round cell deposition was observed on all IOLs in the immediate postoperative period, especially in eyes with uveitis. This reaction decreased 3 to 6 months after surgery. Although the CeeOn 911 had a higher mean grade of small cells, there was no statistical difference between the 3 IOL types after 6 months in the uveitis and control groups. Foreign-body giant cells (FBGCs) increased after 1 week to 1 month. The AcrySof IOLs had the highest number of FBGCs; after 6 months, there was a statistically significant difference between the AcrySof and Hydroview uveitis groups (P =.036) and the AcrySof and CeeOn 911 uveitis groups (P =.003) but there was no difference among the 3 IOL types in the control group. Lens epithelial cell outgrowth persisted on the Hydroview IOLs in control eyes and regressed on all 3 IOL types in uveitic eyes and on the AcrySof and CeeOn 911 IOLs in control eyes (P =.0001). Anterior capsule opacification (ACO) was more severe on all IOL types in uveitic eyes and on the CeeOn 911 IOL in control eyes. Posterior capsule opacification (PCO) was more severe in uveitic eyes. The Hydroview group had more severe PCO than the AcrySof and the CeeOn 911 groups in uveitis and control eyes. Six months postoperatively, the difference was significant (P =.0001). There was no significant difference between the AcrySof and CeeOn 911 IOLs. CONCLUSIONS: Intraocular lens biocompatibility is inversely related to inflammation. Hydrophilic acrylic material had good uveal but worse capsular biocompatibility. Hydrophobic acrylic material had lower uveal but better capsular biocompatibility. Silicone showed a higher small cell count (mild) and more severe ACO but achieved PCO results comparable to FBGC results and better than those with the AcrySof lens 6 months after surgery. Despite the differences in IOL biocompatibility, all patients benefited from the surgery. AD - Department of Ophthalmology, University of Vienna, Medical School, Vienna, Austria. claudette.abela-formanek@akh-wien.ac.at AN - 12106722 AU - Abela-Formanek, C. AU - Amon, M. AU - Schauersberger, J. AU - Kruger, A. AU - Nepp, J. AU - Schild, G. DA - Jul DO - 10.1016/s0886-3350(02)01425-6 DP - NLM ET - 2002/07/11 IS - 7 KW - *Acrylic Resins Aged *Biocompatible Materials Cataract/etiology/*therapy Female Humans Hydrophobic and Hydrophilic Interactions Lens Capsule, Crystalline/pathology Lens Implantation, Intraocular *Lenses, Intraocular Male Middle Aged Phacoemulsification Postoperative Complications/pathology Prospective Studies *Silicone Elastomers Uveitis/complications/*surgery LA - eng N1 - Abela-Formanek, Claudette Amon, Michael Schauersberger, Jörg Kruger, Andreas Nepp, Johannes Schild, Gebtraud Comparative Study Journal Article United States J Cataract Refract Surg. 2002 Jul;28(7):1141-52. doi: 10.1016/s0886-3350(02)01425-6. PY - 2002 SN - 0886-3350 (Print) 0886-3350 SP - 1141-52 ST - Results of hydrophilic acrylic, hydrophobic acrylic, and silicone intraocular lenses in uveitic eyes with cataract: comparison to a control group T2 - J Cataract Refract Surg TI - Results of hydrophilic acrylic, hydrophobic acrylic, and silicone intraocular lenses in uveitic eyes with cataract: comparison to a control group VL - 28 ID - 38 ER - TY - JOUR AN - 104531386. Language: English. Entry Date: 20120413. Revision Date: 20200708. Publication Type: Journal Article AU - Hackney, Catherine AU - Steelman, Victoria M. AU - Moore, Sullen DB - ccm DO - 10.1016/j.aorn.2012.01.001 DP - EBSCOhost IS - 3 KW - Quality Improvement -- Methods Retained Instruments -- Prevention and Control Surgical Count Procedure Patient Safety Surgical Equipment and Supplies N1 - commentary; letter; response. Original Study: Steelman Victoria M, Cullen Joseph J. Designing a safer process to prevent retained surgical sponges: a healthcare failure mode and effect analysis. (AORN J) Aug2011; 94 (2): 132-141. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 0372403. PMID: NLM22381545. PY - 2012 SN - 0001-2092 SP - 317-319 ST - Responses to a quality improvement project on improving the surgical count T2 - AORN Journal TI - Responses to a quality improvement project on improving the surgical count UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104531386&site=ehost-live&scope=site VL - 95 ID - 780 ER - TY - JOUR AD - C. Hackney, Mid coast bariatric surgery, Bundaberg, QLD, Australia AU - Hackney, C. DB - Medline DO - 10.1016/j.aorn.2012.01.001 IS - 3 KW - human letter safety surgical sponge LA - English M3 - Letter N1 - L364351880 2012-06-22 PY - 2012 SN - 0001-2092 SP - 317-318 ST - Response to a quality improvement project on improving the surgical count T2 - AORN Journal TI - Response to a quality improvement project on improving the surgical count UR - https://www.embase.com/search/results?subaction=viewrecord&id=L364351880&from=export http://dx.doi.org/10.1016/j.aorn.2012.01.001 VL - 95 ID - 516 ER - TY - JOUR AB - Background We have been utilizing both resection and laparoscopic radiofrequency ablation (RFA) to treat hepatocellular carcinoma (HCC). The aim of this study is to describe patient characteristics and outcome for each treatment modality from a single institution. Methods Medical records of HCC patients who underwent resection (n = 92) or laparoscopic (RFA) (n = 92) between 1997 and 2010 were reviewed. Univariate Kaplan- Meier and multivariate Cox proportional-hazards model were used to analyze survival. Results Patients with normal liver function and larger tumors were resected, and those with liver dysfunction, portal hypertension, and multiple tumors were ablated. Tumor size was larger in the Resection group, whereas number of tumors was higher in the RFA group. Child class and Barcelona Clinic Liver Cancer (BCLC) staging were more advanced in the RFA group. Hospital stay was longer, and morbidity and mortality higher in the Resection versus the RFA group. There was no difference in diseasefree survival, but the 5-year actual survival was significantly higher (40% versus 21%) in the Resection group. On univariate analysis, number of tumors, tumor size, platelet count, BCLC stage, Child class, and type of surgery were predictors of overall survival. On multivariate analysis, Child class and number of tumors were independent predictors of overall survival. Conclusions To our knowledge, this is the largest North American series reporting on RFA and resection for HCC from a single institution. Herein, we describe the perioperative and oncologic outcomes to be expected when these modalities are used in a certain treatment algorithm. © Springer Science+Business Media, LLC 2011. AD - E. Berber, Department of General Surgery, Liver Tumor Ablation Program, Endocrinology and Metabolism Institute, 9500 Euclid Avenue/F20, Cleveland, OH 44195, United States AU - Karabulut, K. AU - Aucejo, F. AU - Akyildiz, H. Y. AU - Siperstein, A. AU - Berber, E. DB - Embase Medline DO - 10.1007/s00464-011-1983-8 IS - 4 KW - antineoplastic agent abdominal abscess adolescent adult aged article bile leakage cancer staging cancer survival chemoembolization conservative treatment controlled study deep vein thrombosis delirium tremens disease free survival esophagus varices bleeding female hematoma hemihepatectomy human laparoscopic surgery length of stay liver cell carcinoma liver dysfunction liver failure liver function liver resection major clinical study male medical record review morbidity mortality multiple cancer overall survival percutaneous drainage portal hypertension prediction priority journal radiofrequency ablation reoperation respiratory distress retained instrument seroma surgical infection surgical technique platelet count treatment outcome tumor volume wedge resection LA - English M3 - Article N1 - L51691447 2011-11-02 2018-10-30 PY - 2012 SN - 1432-2218 0930-2794 SP - 990-997 ST - Resection and radiofrequency ablation in the treatment of hepatocellular carcinoma: A single-center experience T2 - Surgical Endoscopy TI - Resection and radiofrequency ablation in the treatment of hepatocellular carcinoma: A single-center experience UR - https://www.embase.com/search/results?subaction=viewrecord&id=L51691447&from=export http://dx.doi.org/10.1007/s00464-011-1983-8 VL - 26 ID - 528 ER - TY - JOUR AN - 109809571. Language: English. Entry Date: 20150622. Revision Date: 20200708. Publication Type: Journal Article DB - ccm DO - 10.1016/j.aorn.2015.04.004 DP - EBSCOhost IS - 6 KW - Perioperative Nursing AORN Congresses and Conferences Posters Surgical Count Procedure -- Economics Blood Loss, Surgical Hypothermia -- Prevention and Control Intraoperative Complications -- Prevention and Control Patient Compliance Methicillin-Resistant Staphylococcus Aureus Checklists Documentation Perianesthesia Nursing Nursing Practice, Evidence-Based Warming Techniques Esophagus Body Temperature Patient Safety Surgical Count Procedure Asepsis Radiography, Interventional Time Factors Surgical Fires -- Prevention and Control Surgical Wound Infection -- Prevention and Control Quality Improvement Sterilization and Disinfection Neurosurgery Spine -- Surgery Personnel Recruitment New Graduate Nurses Research, Nursing N1 - abstract; pictorial. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 0372403. PMID: NLM26025738. PY - 2015 SN - 0001-2092 SP - 611-631 ST - Research, Evidence-Based Practice, and Clinical Improvement/Innovation Posters T2 - AORN Journal TI - Research, Evidence-Based Practice, and Clinical Improvement/Innovation Posters UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109809571&site=ehost-live&scope=site VL - 101 ID - 718 ER - TY - JOUR AB - Context Percutaneous endoscopic gastrostomy (PEG) feedings are generally considered safe with few serious complications. Acute pancreatitis is a rare complication associated with replacement percutaneous endoscopic gastrostomy tubes. Case report We report two cases of acute pancreatitis induced by migrated replacement percutaneous endoscopic gastrostomy tubes. Conclusions Migration of a balloon into the duodenum can result in external manipulation of the ampulla of Vater thereby disturbing the flow of pancreatic secretions leading to acute pancreatitis. Recognition of this complication is important and should be included as potential etiology of acute pancreatitis in patients receiving percutaneous endoscopic gastrostomy feedings. Periodic examination and documentation of the distance of the balloon from the skin should be performed to document the position of the tubes or any inadvertent migration of the tubes. The use of Foley catheters as permanent replacement tubes should be considered medically inappropriate. AD - Division of Gastroenterology, School of Health and Medical Sciences, Seton Hall University, South Orange, NJ, United States Department of Internal Medicine, Saint Michael's Medical Center, Newark, NJ, United States AU - Shah, A. M. AU - Shah, N. AU - Depasquale, J. R. DB - Scopus IS - 1 KW - Acute necrotizing abbreviations peg percutaneous endoscopic gastrostomy Enteral nutrition Gastrostomy Pancreatitis M3 - Article N1 - Cited By :12 Export Date: 10 November 2020 PY - 2012 SP - 54-57 ST - Replacement gastrostomy tube causing acute pancreatitis:Case series with review of literature T2 - Journal of the Pancreas TI - Replacement gastrostomy tube causing acute pancreatitis:Case series with review of literature UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84857289576&partnerID=40&md5=13a7018978e5479d6b674c68270be19d VL - 13 ID - 1394 ER - TY - JOUR AB - A small number of cases of small bowel obstruction caused by foods without the formation of phytobezoars have been reported. Repeated small bowel obstruction due to the ingestion of the same food is extremely rare. We present the case of 63-year-old woman who developed small bowel obstruction twice due to the ingestion of chestnuts without the formation of phytobezoars. This is the first reported case of repeated small bowel obstruction caused by chestnut ingestion. Careful interviews are necessary to determine the meal history of elderly patients and psychiatric patients. © 2016 The Japanese Society of Internal Medicine. AD - Department of Gastroenterology, Hirosaki University Graduate School of Medicine, Japan Department of Gastroenterology, Hachinohe City Hospital, Japan Department of Gastroenterology, Mutsu General Hospital, Japan Department of Gastroenterological Surgery, Mutsu General Hospital, Japan Department of Gastroenterology, Kuroishi Hospital, Japan AU - Satake, R. AU - Chinda, D. AU - Shimoyama, T. AU - Satake, M. AU - Oota, R. AU - Sato, S. AU - Yamai, K. AU - Hachimori, H. AU - Okamoto, Y. AU - Yamada, K. AU - Matsuura, O. AU - Hashizume, T. AU - Soma, Y. AU - Fukuda, S. DB - Scopus DO - 10.2169/internalmedicine.55.6811 IS - 12 KW - Chestnut Repeated small bowel obstruction M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2016 SP - 1565-1568 ST - Repeated small bowel obstruction caused by chestnut ingestion without the formation of phytobezoars T2 - Internal Medicine TI - Repeated small bowel obstruction caused by chestnut ingestion without the formation of phytobezoars UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84974667531&doi=10.2169%2finternalmedicine.55.6811&partnerID=40&md5=4ae03fbb2558aeb6b9e52e14dd44e28f VL - 55 ID - 1205 ER - TY - JOUR AB - BACKGROUND Polyacrylamide hydrogel (PAAG) injections were once common in breast augmentation and have been prohibited for augmentation mammaplasty in China since a large number of patients who underwent breast augmentation with PAAG injections have continued to seek medical advice as a result of related complications. Among all these complications, distant migration is relatively rare. CASE SUMMARY A 49-year-old female presented at the hospital with a one-year history of a vulvar lump. The sonography of the lump showed several subcutaneous fluid-filled regions from the left vulva to the pubic symphysis, which suggested possible fat liquefaction. An enhanced magnetic resonance imaging (MRI) revealed a cystic area, which was considered a benign lesion. Intraoperative observations showed that the mass did not have an obvious capsule, the subcutaneous tissue presented as a cavity, and some yellow material came out of this cavity. A culture of the drainage did not show bacterial contamination. Histopathology revealed a foreign body granuloma. After resection and closed drainage, lumps were successively observed in the left lower abdomen and the bilateral hypochondriac region with infections. Sonography found that the hypoechoic areas in the bilateral hypochondriac region seemed continuous with deep in the breasts. The patient reported that she had undergone surgery with PAAG injections 20 years ago after she was repeatedly asked about her past history. Finally, a diagnosis of distant migration of PAAG was made. CONCLUSION PAAG gel can migrate after long periods of time. A diagnosis should not be limited to the area where the symptom develops. © The Author(s) 2019. AD - Department of Diagnostic Ultrasound and Echocardiography, Sir Run Run Shaw Hospital, Zhejiang University College of Medicine, Hangzhou, Zhejiang Province, 310016, China General Surgical Department, Sir Run Run Shaw Hospital, Zhejiang University College of Medicine, Hangzhou, Zhejiang Province, 310016, China Pathology Department, Sir Run Run Shaw Hospital, Zhejiang University College of Medicine, Hangzhou, Zhejiang Province, 310016, China AU - Zhang, M. X. AU - Li, S. Y. AU - Xu, L. L. AU - Zhao, B. W. AU - Cai, X. Y. AU - Wang, G. L. DB - Scopus DO - 10.12998/wjcc.v7.i20.3322 IS - 20 KW - Breast augmentation Case report Distant migration Repeated infection Repeated lump M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 3322-3328 ST - Repeated lumps and infections: A case report on breast augmentation complications T2 - World Journal of Clinical Cases TI - Repeated lumps and infections: A case report on breast augmentation complications UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074629393&doi=10.12998%2fwjcc.v7.i20.3322&partnerID=40&md5=cb050ed942803a9412b66c3ab9da002c VL - 7 ID - 1043 ER - TY - JOUR AD - Division of Cardiology, Department of Internal Medicine, Inje University College of Medicine, Haeundae Paik Hospital, Busan, South Korea AU - Kim, K. H. AU - Seol, S. H. AU - Song, Y. S. AU - Kim, D. K. AU - Kim, D. I. DB - Scopus DO - 10.1016/j.hlc.2017.04.018 IS - 11 M3 - Article N1 - Export Date: 10 November 2020 PY - 2017 SP - e109-e110 ST - Removal of Entrapped Transoesophageal Echocardiography Probe Under the Guidance of Fluoroscopic Imaging T2 - Heart Lung and Circulation TI - Removal of Entrapped Transoesophageal Echocardiography Probe Under the Guidance of Fluoroscopic Imaging UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85020885075&doi=10.1016%2fj.hlc.2017.04.018&partnerID=40&md5=267a4fa4b3034b3ec975b0d4c2712243 VL - 26 ID - 1114 ER - TY - JOUR AB - We report a case of a 14-year-old male with a 17 cm long foreign body in his small bowel. The clinical presentation was non-specific and the diagnosis was made only at laparoscopy. This case study emphasizes the possibility of a linear foreign body in the small bowel which has migrated from the large bowel. This type of migration of the foreign body has not been previously reported. AD - Department of Surgery, Al Sabah Hospital, P.O. Box 4078, Safat 13041, Kuwait AU - Al-enezi, M. AU - Fouad, S. AU - Abul, E. DB - Scopus IS - 4 KW - Foreign body Migration Small bowel M3 - Article N1 - Export Date: 10 November 2020 PY - 2008 SP - 318-320 ST - Removal from the small intestine of a long foreign body (17 cm long pencil) that was introduced per anum T2 - Kuwait Medical Journal TI - Removal from the small intestine of a long foreign body (17 cm long pencil) that was introduced per anum UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-68549083771&partnerID=40&md5=f7c96862fe4c3a3267b66d3745af1592 VL - 40 ID - 1509 ER - TY - JOUR AN - 107459156. Language: English. Entry Date: 19930201. Revision Date: 20150712. Publication Type: Journal Article. Journal Subset: Australia & New Zealand AU - Langslow, A. DB - ccm DP - EBSCOhost IS - 11 KW - Surgical Sponges -- Legislation and Jurisprudence -- United States Foreign Bodies -- Legislation and Jurisprudence -- United States Surgery, Operative -- Legislation and Jurisprudence -- United States Intraoperative Care United States Jurisprudence -- United States Postoperative Complications -- Etiology Adult Male Female N1 - Nursing; Peer Reviewed. NLM UID: 0370074. PMID: NLM1530515. PY - 1992 SN - 0045-0758 SP - 31-32 ST - Relying on the count T2 - Australian Nurses Journal TI - Relying on the count UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107459156&site=ehost-live&scope=site VL - 21 ID - 879 ER - TY - JOUR AB - The techniques used in the diagnosis of gastroesophageal reflux disease (GERD) have insufficient specificity and sensitivity in diagnosing laryngopharyngeal reflux (LPR). The purpose of this study was to evaluate the role of esophagogastroduodenoscopy (EGD) and laryngological examination in the diagnosis of LPR. A total of 684 diagnosed GERD and suspected LPR patients were prospectively scored by the reflux finding score (RFS) which was suggested by Koufman. A total of 484 patients with GERD who had RFS ≥ 7 were accepted as having LPR. 248 patients with GERD plus LPR on whom an endoscopic examination was performed were evaluated. As a control group, results from 82 patients with GERD who had RFS <7 were available for comparison. The GERD symptom score (RSS) was counted according to the existence of symptoms (heartburn/regurgitation) and frequency, duration, and severity. The reflux symptom index (RSI) suggested by Belafsky et al. was also evaluated. The relationship between esophageal endoscopic findings, RSS, RFS and RSI was investigated. Mean age was 46 ± 12 (19-80). The mean values of RSS, RFS, and RSI were 18.9 ± 7.7, 10 ± 2.2, 16.6 ± 11.9, respectively. Erosive esophagitis was detected in 75 cases (30%). Hiatus hernia was observed in 32 patients (13%). There was no correlation between RSS and RFS, RSI. The severity of esophagitis did not correlate with the severity of the laryngeal findings. LPR should be suspected when the history and laryngoscopy findings are suggestive of the diagnosis. EGD has no role in the diagnosis of LPR. AD - Section of Gastroenterology, Ege University School of Medicine, Izmir, Turkey, rukiyevardar@gmail.com. AN - 21881998 AU - Vardar, R. AU - Varis, A. AU - Bayrakci, B. AU - Akyildiz, S. AU - Kirazli, T. AU - Bor, S. DA - Jan DO - 10.1007/s00405-011-1748-y DP - NLM ET - 2011/09/02 IS - 1 KW - Adolescent Adult Aged Aged, 80 and over *Endoscopy, Digestive System Esophagitis, Peptic/complications/diagnosis Female Gastroesophageal Reflux/*complications/diagnosis Hernia, Hiatal/complications Humans Laryngopharyngeal Reflux/complications/*diagnosis *Laryngoscopy Male Middle Aged Young Adult LA - eng N1 - 1434-4726 Vardar, Rukiye Varis, Ahmet Bayrakci, Berna Akyildiz, Serdar Kirazli, Tayfun Bor, Serhat Journal Article Germany Eur Arch Otorhinolaryngol. 2012 Jan;269(1):187-91. doi: 10.1007/s00405-011-1748-y. Epub 2011 Sep 1. PY - 2012 SN - 0937-4477 SP - 187-91 ST - Relationship between history, laryngoscopy and esophagogastroduodenoscopy for diagnosis of laryngopharyngeal reflux in patients with typical GERD T2 - Eur Arch Otorhinolaryngol TI - Relationship between history, laryngoscopy and esophagogastroduodenoscopy for diagnosis of laryngopharyngeal reflux in patients with typical GERD VL - 269 ID - 112 ER - TY - JOUR AB - This study reviews the cochlear histology from four hearing preservation cochlear implantation experiments conducted on 73 guinea pigs from our institution, and relates histopathological findings to residual hearing. All guinea pigs had normal hearing prior to surgery and underwent cochlear implantation via a cochleostomy with a silastic-platinum dummy electrode. Pure tone auditory brainstem response (ABR) thresholds from 2 to 32 kHz were recorded prior to surgery, and at one and four weeks postoperatively. The cochleae were then fixed in paraformaldehyde, decalcified, paraffin embedded, and mid-modiolar sections were prepared. The treatment groups were as follows: 1) Systemic dexamethasone, 0.2 mg/kg administered 1 h before implantation, 2) Local dexamethasone, 2% applied topically to the round window for 30 min prior to cochlear implantation, 3) Local n-acetyl cysteine, 200 μg applied topically to the round window for 30 min prior to implantation, 4) inoculation to keyhole-limpet hemocyanin (KLH) prior to implantation, and 5) untreated controls. There was a significant correlation between the extent of the tissue reaction in the cochlea and the presence of foreign body giant cells (FBGCs), new bone formation and injury to the osseous spiral lamina (OSL). The extent of the tissue response, as a percentage of the area of the scala tympani, limited the best hearing that was observed four weeks after cochlear implantation. Poorer hearing at four weeks correlated with a more extensive tissue response, lower outer hair cell (OHC) counts and OSL injury in the basal turn. Progressive hearing loss was also correlated with the extent of tissue response. Hearing at 2 kHz, which corresponds to the region of the second cochlear turn, did not correspond with loco-regional inner hair cell (IHC), OHC or SGC counts. We conclude that cochlear injury is associated with poorer hearing early after implantation. The tissue response is related to indices of cochlear inflammation and injury. An extensive tissue response limits hearing at four weeks, and correlates with progressive hearing loss. These latter effects may be due to inflammation, but would also be consistent with interference of cochlear mechanics. © 2013. AD - Department of Otolaryngology, University of Melbourne, Royal Victorian Eye and Ear Hospital, 2nd Floor, Peter Howson Wing, 32 Gisborne St., East Melbourne, VIC 3002, Australia Queen Elizabeth Medical Centre, Birmingham, West Midlands B15 2TH, United Kingdom Geelong Hospital, 72-322 Ryrie Street, Geelong, VIC, Australia Christchurch Hospital, Riccarton Avenue, Private Bag 4710, Christchurch, New Zealand Southern Health, Monash Medical Centre, Vic., Australia Bionics Institute, 384-388 Albert St., East Melbourne, VIC, Australia AU - O'Leary, S. J. AU - Monksfield, P. AU - Kel, G. AU - Connolly, T. AU - Souter, M. A. AU - Chang, A. AU - Marovic, P. AU - O'Leary, J. S. AU - Richardson, R. AU - Eastwood, H. DB - Scopus DO - 10.1016/j.heares.2013.01.012 M3 - Article N1 - Cited By :84 Export Date: 10 November 2020 PY - 2013 SP - 27-35 ST - Relations between cochlear histopathology and hearing loss in experimental cochlear implantation T2 - Hearing Research TI - Relations between cochlear histopathology and hearing loss in experimental cochlear implantation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84875809542&doi=10.1016%2fj.heares.2013.01.012&partnerID=40&md5=431f162ae46e2b751c9f8ba4a0d57bec VL - 298 ID - 1324 ER - TY - JOUR AB - Background: Immunocompromised hematologic malignancy (HM) patients experience high mortality after respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI). We measured radiologic severity to determine whether it could improve the performance of 60-day mortality models based only upon immunodeficiency severity. Methods: We studied 155 HM patients, including 84 hematopoietic cell transplant recipients, who developed RSV LRTI from 2001 to 2013. We measured immunodeficiency using lymphopenia (lymphocyte count <200 cells/mm3), Immunodeficiency Severity Index (ISI), and Severe Immunodeficiency (SID) criteria. Radiologic severity was measured by the Radiologic Severity Index (RSI, range 0-72) at time of LRTI (baseline-RSI) and peak severity (peak-RSI). Delta-RSI was defined as the difference between baseline-RSI and peak-RSI. We used logistic regression models to measure the association of immunodeficiency and RSI with 60-day all-cause mortality, and measured model discrimination using areas under the receiver-operating characteristics curves, calibration using Brier scores, and explained variance using pseudo-R2 values. Results: Forty-one patients died within 60 days of RSV LRTI. Severe immunodeficiency was associated with higher mortality. Peak-RSI (odds ratio [OR] 1.06/point, 95% confidence interval [CI] 1.04-1.08), and delta-RSI (OR 1.07/point, 95% CI 1.05-1.10) were associated with 60-day mortality after RSV LRTI, but not baseline-RSI. Addition of peak-RSI or delta-RSI to baseline immunodeficiency improved the discrimination, calibration, and explained variance (P < 0.001) of 60-day mortality models. Conclusions: Although baseline immunodeficiency in HM patients helps predict 60-day mortality after RSV LRTI, mortality risk estimates can be further refined by also measuring LRTI progression using RSI. RSI is well-suited as a marker of LRTI severity in RSV infection. AD - A. Sheshadri, Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States AU - Sheshadri, A. AU - Karimipour, M. AU - Vakil, E. AU - Bashoura, L. AU - Godoy, M. AU - Arain, M. H. AU - Evans, S. E. AU - Dickey, B. F. AU - Ost, D. E. AU - Chemaly, R. F. AU - Faiz, S. A. DB - Embase Medline DO - 10.1111/tid.13105 IS - 4 KW - adult all cause mortality allogeneic hematopoietic stem cell transplantation article assessment of humans autologous hematopoietic stem cell transplantation disease severity assessment female graft recipient hematologic malignancy human immune deficiency Immunodeficiency Severity Index leukemia lower respiratory tract infection lymphocyte count lymphocytopenia lymphoma major clinical study male medical record review middle aged mortality risk multiple myeloma priority journal Radiologic Severity Index respiratory syncytial virus infection retrospective study Severe Immunodeficiency criteria LA - English M3 - Article N1 - L2002468191 2019-08-21 2019-08-26 PY - 2019 SN - 1399-3062 1398-2273 ST - Refinement of estimates of mortality risk using the Radiologic Severity Index in hematologic malignancy patients with respiratory syncytial virus infection T2 - Transplant Infectious Disease TI - Refinement of estimates of mortality risk using the Radiologic Severity Index in hematologic malignancy patients with respiratory syncytial virus infection UR - https://www.embase.com/search/results?subaction=viewrecord&id=L2002468191&from=export http://dx.doi.org/10.1111/tid.13105 VL - 21 ID - 323 ER - TY - JOUR AB - Background: Unintended retained surgical sponges (URSSs) are preventable catastrophic events that occur in the surgical environment. Purpose: A community hospital in the southern United States sought to reduce the occurrence of URSSs by implementing a quality improvement initiative. Methods: We conducted a practice improvement project that incorporated safety-sponge technology preceded by education and training. Staff knowledge and practice expectations were assessed using a pre-post-intervention survey followed by internal audit. Results: Staff knowledge significantly improved after the tailored education and training. A chart audit conducted 15 weeks after the intervention showed compliance with the technology was 99.4%, incorrect surgical counts went from 4% to 0.8%, and number of URSSs went from 2 to 0. Conclusion: The project demonstrated a reduced risk of incorrect surgical counts and URSSs in the facility. © 2020 AD - University of Miami, School of Nursing and Health Studies, 5030 Brunson Drive, Room 315, Coral Gables, FL 33146, United States AU - Grant, E. K. AU - Gattamorta, K. A. AU - Foronda, C. L. C7 - 100099 DB - Scopus DO - 10.1016/j.pcorm.2020.100099 M3 - Article N1 - Export Date: 10 November 2020 PY - 2020 ST - Reducing the risk of unintended retained surgical sponges: A quality improvement project T2 - Perioperative Care and Operating Room Management TI - Reducing the risk of unintended retained surgical sponges: A quality improvement project UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85082862733&doi=10.1016%2fj.pcorm.2020.100099&partnerID=40&md5=6f4a285d0b51e8afae485bd5ed59f875 VL - 21 ID - 949 ER - TY - JOUR AB - Patient safety is one of the most pressing challenges in health care. The promotion of safety requires that all those involved in healthcare realise that the potential for errors exists, and that teamwork and communication are essential for preventing errors. Incidents compromising patient safety, such as unintended retention of swabs or instruments, are regarded as 'never events'. These incidents are considered 'unacceptable and eminently preventable', as pointed out by the Department of Health 'never events list' 2012/2013. One estimate says that one case of a retained item occurs at least once a year in a major hospital where 8000 to 18,000 major cases are carried out each year. All healthcare organisations should take appropriate measures to prevent retention of foreign bodies by consistent application of reliable and standardised processes of care. In this review, we explore the risks and complications associated with retained swabs and instruments, and different ways to prevent such risks to patients. © 2013 Elsevier Ltd. All rights reserved. AD - Norfolk and Norwich University Hospital, NHS Foundation Trust, Colney Lane, Norwich, Norfolk NR4 7UY, United Kingdom AU - Mahran, M. A. AU - Toeima, E. AU - Morris, E. P. DB - Scopus DO - 10.1016/j.bpobgyn.2013.03.001 IS - 4 KW - gossypiboma misplaced swab retained swab retained swabs and instruments swab count M3 - Article N1 - Cited By :11 Export Date: 10 November 2020 PY - 2013 SP - 489-495 ST - The recurring problem of retained swabs and instruments T2 - Best Practice and Research: Clinical Obstetrics and Gynaecology TI - The recurring problem of retained swabs and instruments UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84880041190&doi=10.1016%2fj.bpobgyn.2013.03.001&partnerID=40&md5=304029445ad888c462da3497cbfdddd8 VL - 27 ID - 1314 ER - TY - JOUR AB - Patient safety is one of the most pressing challenges in health care. The promotion of safety requires that all those involved in healthcare realise that the potential for errors exists, and that teamwork and communication are essential for preventing errors. Incidents compromising patient safety, such as unintended retention of swabs or instruments, are regarded as 'never events'. These incidents are considered 'unacceptable and eminently preventable', as pointed out by the Department of Health 'never events list' 2012/2013. One estimate says that one case of a retained item occurs at least once a year in a major hospital where 8000 to 18,000 major cases are carried out each year. All healthcare organisations should take appropriate measures to prevent retention of foreign bodies by consistent application of reliable and standardised processes of care. In this review, we explore the risks and complications associated with retained swabs and instruments, and different ways to prevent such risks to patients. AD - Norfolk and Norwich University Hospital NHS Foundation Trust, Colney Lane, Norwich, Norfolk NR4 7UY, UK. AN - 23578840 AU - Mahran, M. A. AU - Toeima, E. AU - Morris, E. P. DA - Aug DO - 10.1016/j.bpobgyn.2013.03.001 DP - NLM ET - 2013/04/13 IS - 4 KW - Delivery, Obstetric/adverse effects Foreign Bodies/diagnosis/etiology/*prevention & control Humans Medical Errors/adverse effects/*prevention & control Patient Safety/*standards Postoperative Complications/diagnosis/etiology/*prevention & control Risk Factors Surgical Instruments Surgical Sponges gossypiboma misplaced swab retained swab retained swabs and instruments swab count LA - eng N1 - 1532-1932 Mahran, Montasser A Toeima, Eman Morris, Edward P Journal Article Review Netherlands Best Pract Res Clin Obstet Gynaecol. 2013 Aug;27(4):489-95. doi: 10.1016/j.bpobgyn.2013.03.001. Epub 2013 Apr 8. PY - 2013 SN - 1521-6934 SP - 489-95 ST - The recurring problem of retained swabs and instruments T2 - Best Pract Res Clin Obstet Gynaecol TI - The recurring problem of retained swabs and instruments VL - 27 ID - 137 ER - TY - JOUR AB - Embolization of a severed tube of a ventriculo-atrial shunt into the heart is a rare but severe and potentially lethal complication of aresorptive hydrocephalus therapy in patients with severe neurological damage. A rare case is presented of a 53-year-old woman who suffered a severe subarachnoidal haemorrhage. After infection of the first shunting system, the patient underwent an exchange of the system, but repeatedly showed clinical and laboratory signs of infection which failed to improve despite several antibiotic treatments. This case illustrates that, although the patient was in poor neurological and medical condition, it is beneficial to remove the accidentally washed-in foreign body for two reasons. On the one hand to prevent avoidable life-threatening incidents, on the other hand to gain stable medical condition which will allow the patient to participate in neurorehabilitative treatment. AD - Rehabilitation Centre for Head Injury Patients, Austrian Worker's Compensation Board (AUVA), Vienna, Austria AU - Blazicek, H. AU - Oder, W. DB - Scopus DO - 10.1080/02699050701210459 IS - 3 KW - Aresorptive hydrocephalus Medical complication Ventriculo-atrial shunt M3 - Article N1 - Export Date: 10 November 2020 PY - 2007 SP - 339-341 ST - Recurrent fever in patient in a minimally responsive state: An unusual origin of infection T2 - Brain Injury TI - Recurrent fever in patient in a minimally responsive state: An unusual origin of infection UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-34147179494&doi=10.1080%2f02699050701210459&partnerID=40&md5=3752fae3f35cad979ae991e26d02cf5c VL - 21 ID - 1569 ER - TY - JOUR AB - Background: The dermoid cyst considered a cystic teratoma derived from embryonic germinal epithelium is a slow-growing benign tumour. Dermoid cysts may occur in the orbital and periorbital region in paediatric patients and are often recurrent. The surgical approach depends upon the site of the lesion, superficial or deep. To our knowledge, this is the first described case of a patient with resection of dermoid cyst treated with human amniotic membrane implant and topical application of 0.02% mitomycin C. Case presentation: We present a case of a 12-year-old male with a tumour in the superotemporal region of the right eye (RE). Symptoms included decreased visual acuity (VA), burning eye, foreign body sensation, and photophobia of the affected eye. A physical examination detected blepharospasm. Ophthalmic examination of his RE, fingers count from a 1-2 m distance, showed no improvement with pinhole. Visual acuity was 20/20 on the left eye (LE). The bio-microscopic examination confirmed the presence of a tumour mass (15 mm × 12 mm) on the surface of the RE, invading the superotemporal sector. The tumour had a lobulated appearance, a shiny and vascularized surface covered by conjunctiva, a pearlescent-pink colour, a medium consistency, was renitent and painless. An ultrasound scan revealed atrophy of the pigmented retinal epithelium with scleral indentation of the RE. A computed tomography (CT) scan revealed a recurrent lesion consistent with an epibulbar dermoid cyst. Surgical excision of the lesion was performed and a human amniotic membrane (HAM) graft and topical 0.02% mitomycin C (MMC) were applied. Histopathological analysis confirmed the diagnosis of recurrent dermoid cyst. Conclusion: In this case report, we describe a case of recurrent epibulbar dermoid cyst treated with complete resection; topical MMC and HAM implant with good clinical outcome of the lesion and implant adhesion. Resection of a cyst of the ocular surface is not recommended when a large epibulbar dermoid tissue needs to be resected and no HAM graft is available. © 2018 The Author(s). AD - Californias' Children Hospital Ophthalmology Service, Av. Alejandro Von Humboldt 11431, Garita de Otay, Tijuana, BC, 22509, Mexico School of Health Sciences, Valle de Las Palmas, Autonomous University of Baja California, Blvd Universitario 1000, Valle de Las Palmas, Tijuana, BC, 22260, Mexico Fray Junípero Serra Hospital, Security and Social Services Institute for State Workers, Tijuana, Avenida De Las Palmas 1 Col Las Palmas, Tijuana, BC, 22106, Mexico Interdisciplinary Research Center for the Comprehensive Regional Development, Durango Module, Durango, Mexico National Polytechnic Institute, Sigma Street #119, Fracc. 20 de Noviembre II, Durango Dgo. C.P. 34220, Año, 2009-2010, Mexico Department of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja California, Parque Industrial Internacional Tijuana, Av. Universidad no 14418, Tijuana, BC, CP. 22390, Mexico AU - Villalón, M. L. AU - Leal, M. D. L. Á AU - Chávez, J. R. AU - Santillán, E. M. AU - Lares-Asseff, I. AU - Loera, V. AU - Valencia, L. AU - Camacho, B. AU - Alvarado, B. AU - Cervantes, V. AU - Patrón, L. AU - Almanza, H. C7 - 98 DB - Scopus DO - 10.1186/s12893-018-0426-z IS - 1 KW - Amniotic membrane Dermoid cyst Mitomycin c M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2018 ST - Recurrent epibulbar dermoid cyst treated with amniotic membrane implant a case report 11 Medical and Health Sciences 1113 Ophthalmology and Optometry T2 - BMC Surgery TI - Recurrent epibulbar dermoid cyst treated with amniotic membrane implant a case report 11 Medical and Health Sciences 1113 Ophthalmology and Optometry UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85056606085&doi=10.1186%2fs12893-018-0426-z&partnerID=40&md5=504204d352541e9ca87e576dd25fba6e VL - 18 ID - 1055 ER - TY - JOUR AB - BACKGROUND: The dermoid cyst considered a cystic teratoma derived from embryonic germinal epithelium is a slow-growing benign tumour. Dermoid cysts may occur in the orbital and periorbital region in paediatric patients and are often recurrent. The surgical approach depends upon the site of the lesion, superficial or deep. To our knowledge, this is the first described case of a patient with resection of dermoid cyst treated with human amniotic membrane implant and topical application of 0.02% mitomycin C. CASE PRESENTATION: We present a case of a 12-year-old male with a tumour in the superotemporal region of the right eye (RE). Symptoms included decreased visual acuity (VA), burning eye, foreign body sensation, and photophobia of the affected eye. A physical examination detected blepharospasm. Ophthalmic examination of his RE, fingers count from a 1-2 m distance, showed no improvement with pinhole. Visual acuity was 20/20 on the left eye (LE). The bio-microscopic examination confirmed the presence of a tumour mass (15 mm × 12 mm) on the surface of the RE, invading the superotemporal sector. The tumour had a lobulated appearance, a shiny and vascularized surface covered by conjunctiva, a pearlescent-pink colour, a medium consistency, was renitent and painless. An ultrasound scan revealed atrophy of the pigmented retinal epithelium with scleral indentation of the RE. A computed tomography (CT) scan revealed a recurrent lesion consistent with an epibulbar dermoid cyst. Surgical excision of the lesion was performed and a human amniotic membrane (HAM) graft and topical 0.02% mitomycin C (MMC) were applied. Histopathological analysis confirmed the diagnosis of recurrent dermoid cyst. CONCLUSION: In this case report, we describe a case of recurrent epibulbar dermoid cyst treated with complete resection; topical MMC and HAM implant with good clinical outcome of the lesion and implant adhesion. Resection of a cyst of the ocular surface is not recommended when a large epibulbar dermoid tissue needs to be resected and no HAM graft is available. AD - The Californias' Children Hospital Ophthalmology Service, Av. Alejandro Von Humboldt 11431, Garita de Otay, 22509, Tijuana, BC, Mexico. School of Health Sciences, Valle de Las Palmas, Autonomous University of Baja California, Blvd Universitario 1000, Valle de Las Palmas, 22260, Tijuana, BC, Mexico. Fray Junípero Serra Hospital, Security and Social Services Institute for State Workers, Tijuana, Avenida De Las Palmas 1 Col Las Palmas, 22106, Tijuana, BC, Mexico. Interdisciplinary Research Center for the Comprehensive Regional Development, Durango Module, Durango, Mexico. National Polytechnic Institute, Sigma Street #119, Fracc. 20 de Noviembre II, C.P. 34220. Año 2009-2010, Durango Dgo., Mexico. Department of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja California, Av. Universidad no 14418, Parque Industrial Internacional Tijuana, CP. 22390, Tijuana, BC, Mexico. Department of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja California, Av. Universidad no 14418, Parque Industrial Internacional Tijuana, CP. 22390, Tijuana, BC, Mexico. almanzareyes@uabc.edu.mx. AN - 30428870 AU - Villalón, M. L. AU - Leal, MlÁ AU - Chávez, J. R. AU - Santillán, E. M. AU - Lares-Asseff, I. AU - Loera, V. AU - Valencia, L. AU - Camacho, B. AU - Alvarado, B. AU - Cervantes, V. AU - Patrón, L. AU - Almanza, H. C2 - PMC6236942 DA - Nov 14 DO - 10.1186/s12893-018-0426-z DP - NLM ET - 2018/11/16 IS - 1 KW - Amnion/*transplantation Child Dermoid Cyst/*surgery Humans Male Orbital Neoplasms/*surgery Tomography, X-Ray Computed Ultrasonography Amniotic membrane Dermoid cyst Mitomycin c approved by the Bioethics Committee of the Faculty of Medicine and Psychology of the Autonomous University of Baja California No. 935/2013–2. CONSENT FOR PUBLICATION: Written informed consent was obtained from the patient for publication of this Case report and any accompanying images. A copy of the written consent form is available for review by the Editor of this journal. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. LA - eng N1 - 1471-2482 Villalón, Ma Luisa Leal, Ma De Los Ángeles Chávez, José R Santillán, Eduardo M Lares-Asseff, Ismael Loera, Verónica Valencia, Laura Camacho, Blanca Alvarado, Brenda Cervantes, Vilma Patrón, Leslie Almanza, Horacio Orcid: 0000-0002-1874-3975 2013-1-201204/Consejo Nacional de Ciencia y Tecnología/ Case Reports Journal Article BMC Surg. 2018 Nov 14;18(1):98. doi: 10.1186/s12893-018-0426-z. PY - 2018 SN - 1471-2482 SP - 98 ST - Recurrent epibulbar dermoid cyst treated with amniotic membrane implant a case report T2 - BMC Surg TI - Recurrent epibulbar dermoid cyst treated with amniotic membrane implant a case report VL - 18 ID - 223 ER - TY - JOUR AB - Introduction: Retained or dropped appendicolith is an uncommon complication that can occur as a consequence of stone expulsion from the appendix before or during appendectomy. This phenomenon is frequently associated with intra-abdominal abscess of variable locations; therefore, recognition of its presence is of great clinical significance in the care of patients with post appendectomy abscesses. Case Report: A 45-year-old woman underwent a laparoscopic appendectomy for perforated appendicitis. She was discharged asymptomatic on the 3rd postoperative day. She developed fever and epigastric abdominal pain 5 days later and she also had a white blood cell count of 13,000. Computed tomography (CT) showed a collection in epigastric region containing a small calcified stone; she was placed on IV antibiotics and underwent a CTguided percutaneous drainage. Despite this, 3 weeks after she was discharged asymptomatic the epigastric collection recurred. A new CT showed the persistence of the retained appendicolith and the abscess in the epigastric region. A small open laparotomy was performed, during which the abscess was drained and the appendicolith was removed. Conclusions: Laparoscopic appendectomy is complicated by postoperative abscess five times more frequently than open surgery. Retained appendicolith can cause abscess formation after surgery and can be a source of persistent infection. The abscess can appear within weeks or months after the initial appendectomy. A systematic division of the appendix performed between double ligature helps to avoid this postoperative complication. Removal of retained appendicolith is necessary because it may act as an infected foreign body, which cannot be sterilized by antibiotics or with simple drainage alone. Treatment options include open, percutaneous, or laparoscopic drainage of the abscess and retrieval of the appendicolith; Percutaneous drainage is commonly used to treat intra-abdominal abscess, but it is in some cases ineffective for retained appendicolith removal, requiring laparoscopic access or, using an open access as it was required in our case. AD - A. Reyhani Calvo, Hospital Universitario De Alava (Sede Santiago), Vitoria, Spain AU - Reyhani Calvo, A. AU - Martin Martin, E. AU - Cendoya Ansola, I. AU - Arteche Daubagna, E. AU - Gómez Portilla, A. AU - López De Heredia Armentia, E. AU - Magrach Barcenilla, L. A. AU - Palacios Bazan, E. E. AU - Ezurmendia Sinisterra, B. AU - Larrañaga Zabaleta, M. AU - Etxart Lopetegui, A. DB - Embase DO - 10.1007/s00464-015-4136-7 KW - antibiotic agent endoscopic surgery appendectomy European abscess human abdominal abscess surgery percutaneous drainage persistent infection appendix perforation patient computer assisted tomography leukocyte count abdominal pain laparotomy foreign body postoperative complication fever case report female LA - English M3 - Conference Abstract N1 - L71872935 2015-05-13 PY - 2015 SN - 0930-2794 SP - S171 ST - Recurrent abscess due to retained appendicolith after laparoscopic appendectomy T2 - Surgical Endoscopy and Other Interventional Techniques TI - Recurrent abscess due to retained appendicolith after laparoscopic appendectomy UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71872935&from=export http://dx.doi.org/10.1007/s00464-015-4136-7 VL - 29 ID - 434 ER - TY - JOUR AB - INTRODUCTION AND OBJECTIVES: Severe intrinsic sphincter deficiency (ISD) is a common cause of failed stress urinary incontinence (SUI) surgery. Management of women with multiple failed surgeries is particularly challenging, and these women are candidates for artificial sphincter implantation or continent urinary diversion. We present our experience with rectus fascia spiral sling (RFSS) in women with treatment-refractory ISD. METHODS: Four women (age: 19-64) underwent RFSS between 2011-2014. All women had severe incontinence with minimal activity or a slight change in body position. All had undergone multiple (range: 2-5) surgeries for SUI. Clinical evaluation included subjective assessment with ICIQ-SF questionnaire, pelvic physical examination, and urodynamic studies. All patients demonstrated marked ISD with a valsalva leak point pressure <60 cm H2O. The severity of SUI was evaluated by measuring the amount of urine leaked during a 24-h pad test and by counting the number of pads per day. A combined transvaginal+retropubic approach was utilized to remove all foreign material (permanent sutures and/or synthetic mesh) from previous surgeries and to completely dissect the urethra from the surrounding fibrosis. Using a right-angle clamp introduced from the anterior vaginal wall incision, the dorsal urethral plane was dissected with its tip advancing towards the contralateral side of the incision. The mid-urethra was thus mobilized circumferentially, followed by placement of a 8-10 cm × 1-1.5 cm rectus fascia sling around the mid-urethra in a tension-free manner. Urethral catheter was removed after 3-5 days. Postoperative visits were scheduled at 1, 3, 6, 12 months, and yearly thereafter. RESULTS: Bladder neck was entered in one patient during retropubic dissection. RFSS was completed without any consequence after primary repair. One patient received concomitant ileocystoplasty due to small-capacity (ie. 100 cc) bladder. No women developed urinary retention or voiding dysfunction necessitating intermittent catheterization. With a mean follow-up of 10 months (range: 3-24), SUI was cured in 2 (0-1 pad/day) and significantly improved in 2 women. Mean number of pads/ day decreased from 6.25 preoperatively to 1.25 postoperatively (p=0.03). Mean ICIQ-SF score decreased from 18.75±1.5 preoperatively to 6.5±2.5 postoperatively (p=0.01, Wilcoxon signed-rank test). CONCLUSIONS: RFSS is an effective option in women with treatment-refractory ISD, which may be considered before proceeding to more invasive treatment modalities. AD - F.F. Onol, Istanbul, Turkey AU - Onol, F. F. AU - Onol, S. Y. AU - Gürbüz, M. C. AU - Tahra, A. AU - Küc¸ük, E. V. DB - Embase IS - 4 KW - fascia female human stress incontinence surgery American urethra patient incision ICIQ (incontinence) sphincter patient history of surgery foreign body urinary diversion aorta root prosthesis follow up Wilcoxon signed ranks test invasive procedure urine suture intermittent catheterization urine retention physical examination pelvis dissection questionnaire bladder neck urethral catheter bladder clinical evaluation clamp fibrosis body position incontinence implantation LA - English M3 - Conference Abstract N1 - L71858020 2015-04-29 PY - 2015 SN - 0022-5347 SP - e98 ST - Rectus fascia spiral sling (RFSS) technique for women with multiple failed stress incontinence surgery due to severe intrinsic sphincteric deficiency T2 - Journal of Urology TI - Rectus fascia spiral sling (RFSS) technique for women with multiple failed stress incontinence surgery due to severe intrinsic sphincteric deficiency UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71858020&from=export VL - 193 ID - 432 ER - TY - JOUR AB - The fetal heart rate is one of the best indicators of the fetal status during labor. The heart rate is counted by means of the fetal ECG (FECG) obtained from the maternal abdominal wall or a direct ECG from the fetal scalp after rupture of the amnionic sac. However, these methods are not satisfactory by reason of poor signal-to-noise ratio, difficulty in continuous monitoring, and so on. Accordingly, radiotelemetry was employed for measurement of fetal heart rate (FHR), an adequate size transmitter combined with electrodes being inserted into the uterine space. The direct FECG was transmitted throughout all stages of labor and was received by a commercial short-wave radio receiver placed near by. The ECG of the newborn baby was also taken from the axilla with ease by a clip electrode-transmitter consisting of a clip electrode for adult limb leads and a smaller trans-mitter. The carrier frequency was chosen at about 6 Mc/s and the amplitude was modulated by the signal. The size and the form of the transmitter were arranged to allow easy insertion into the uterine space, complete contact with the amnionic sac and easy exchange of the battery, while not behaving as a foreign body and not being exhausted by delivery. After construction in the form of a printed circuit, the transmitter enclosed in a mold of silicon rubber to prevent injury to the body and to ensure insulation from the tissues. The total weight and volume were 15 g and 9 cm3, respectively. Drain current was 200 ìÁwith a receiving range of about 1.5 meter. ECGs of 6 fetuses including 3 cases of cesarean section were investigated throughout labor and delivery. Especially interesting results were obtained when FHRs were registered before and after rupture of the amnionic sac, labor, delivery and ligation of the umbilical cord and during cesarean section. (27, 2A). AD - H. Tazawa, Dept. of Med. Electron., Res. Inst. of Appl. Electr, Hokkaido Univ., Sapporo AU - Tazawa, H. DB - Embase Classic IS - 1 KW - silastic abdominal wall adult axilla baby cesarean section clip electrocardiogram electrode electroencephalogram electromyogram fetus fetus electrocardiography fetus heart rate foreign body heart rate injury Japanese (people) ligation limb monitoring newborn recording rupture scalp signal noise ratio telemetry tissues umbilical cord uterine cervix uterus weight LA - English M3 - Article N1 - L288035549 1968-12-01 PY - 1968 SN - 0021-3292 SP - 70-75 ST - Recording of fetal electrocardiogram by means of intrauterine transmitter (japanese) T2 - Japanese journal of medical electronics and biological engineering TI - Recording of fetal electrocardiogram by means of intrauterine transmitter (japanese) UR - https://www.embase.com/search/results?subaction=viewrecord&id=L288035549&from=export VL - 6 ID - 691 ER - TY - JOUR AB - Fetal heart rate is known as one of the best representations of the fetal situations in labor. The heart rate is counted by means of FECG or FPCG obtained from the maternal abdominal wall or direct ECG from the fetal scalp after rupture of the amnionic sac. However, these methods are not satisfactory by the reasons of poor signal to noise ratio, difficulty in continuous monitoring, and so on. Accordingly, we applied the radiotelemetry to measurement of FHR, in which an adequate size transmitter combined withelectrodes was inserted into the uterine space. The direct FECG was transmitted throughout all stages of labor and received by a commercial short wave radio receiver placed near by. And ECG of the newborn baby was also taken from the axilla with ease by a clip electrodetransmitter consisting a clip electrode for adult limb lead and a small transmitter. The carrier frequency was chosen at about 6 Mc/s and the amplitude was modulated by the signal. The size and the form of the transmitter were determined to allow easy insertion to uterine space, complete contact with the amnionic sac and easy exchange of the battery, and not to behave as a foreign body and not to being exhausted by delivery. After construction on the board of printed wiring, the transmitter was molded by silicon rubber. to prevent from injuring the body and to be insulated from the tissues. The total weight and volume were 15 g and 9 cm3, respectively. Drain current was 200 μA with the receiving range of about 1.5 meter. ECGs of six fetuses including three cases of cesarean section were investigated throughout labor and delivery. Especially interesting results were obtained of FHRs before and after rupture of the amnionic sac, labor, delivery and ligation of the umbilical cord and during cesarean section. © 1968, Japanese Society for Medical and Biological Engineering. All rights reserved. AD - Department of Medical Electronics, The Research Institute of Applied Electricity, Hokkaido University, Japan 1st Department of Medical Electronics, The Research Institute of Applied Electricity, Hokkaido University, Japan AU - Tazawa, H. AU - Wada, T. AU - Yoshimoto, C. AU - Oguni, C. DB - Scopus DO - 10.11239/jsmbe1963.6.70 IS - 1 M3 - Article N1 - Export Date: 10 November 2020 PY - 1968 SP - 70-75 ST - Recording of fetal electrocardiogram by means of intrauterine transmitter T2 - Japanese journal of medical electronics and biological engineering TI - Recording of fetal electrocardiogram by means of intrauterine transmitter UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84996415129&doi=10.11239%2fjsmbe1963.6.70&partnerID=40&md5=a934cb17ffc7f5a90f549f38be2506cd VL - 6 ID - 1788 ER - TY - JOUR AN - 106448789. Language: English. Entry Date: 20060602. Revision Date: 20200708. Publication Type: Journal Article DB - ccm DO - 10.1016/S0001-2092(06)60172-5 DP - EBSCOhost IS - 2 KW - AORN -- Standards Operating Rooms -- Standards Perioperative Nursing -- Standards Surgical Count Procedure -- Standards Documentation -- Standards Retained Instruments -- Prevention and Control N1 - glossary; standards. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PMID: NLM16544861. PY - 2006 SN - 0001-2092 SP - 418-426 ST - Recommended practices for sponge, sharps, and instrument counts...originally published May 1976, AORN Journal, as 'Standards for sponge, needle, and instrument procedures' T2 - AORN Journal TI - Recommended practices for sponge, sharps, and instrument counts...originally published May 1976, AORN Journal, as 'Standards for sponge, needle, and instrument procedures' UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106448789&site=ehost-live&scope=site VL - 83 ID - 801 ER - TY - JOUR DB - Scopus DO - 10.1016/S0001-2092(06)60172-5 IS - 2 M3 - Article N1 - Cited By :16 Export Date: 10 November 2020 PY - 2006 SP - 418, 421-426, 429-433 ST - Recommended practices for sponge, sharps, and instrument counts T2 - AORN journal TI - Recommended practices for sponge, sharps, and instrument counts UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33646831340&doi=10.1016%2fS0001-2092%2806%2960172-5&partnerID=40&md5=998a6fe8e35d8ed64cf0e4de63ea2ba9 VL - 83 ID - 1588 ER - TY - JOUR AN - 10635432 DA - Dec DO - 10.1016/s0001-2092(06)62224-2 DP - NLM ET - 2000/01/15 IS - 6 KW - Documentation Foreign Bodies/*prevention & control Humans Nursing Records Perioperative Nursing/methods/*standards *Surgical Instruments/standards Surgical Procedures, Operative/nursing Surgical Sponges United States LA - eng N1 - Guideline Journal Article Practice Guideline United States AORN J. 1999 Dec;70(6):1083-9. doi: 10.1016/s0001-2092(06)62224-2. PY - 1999 SN - 0001-2092 (Print) 0001-2092 SP - 1083-9 ST - Recommended practices for sponge, sharp, and instrument counts. AORN Recommended Practices Committee. Association of periOperative Registered Nurses T2 - Aorn j TI - Recommended practices for sponge, sharp, and instrument counts. AORN Recommended Practices Committee. Association of periOperative Registered Nurses VL - 70 ID - 30 ER - TY - JOUR AN - 107124371. Language: English. Entry Date: 20000801. Revision Date: 20150818. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 7 KW - Patient Safety Surgical Count Procedure Documentation Registered Nurses Perioperative Nursing Surgical Sponges Needles Surgical Instruments Practice Guidelines AORN -- Standards United States Operating Room Personnel N1 - practice guidelines. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2000 SN - 0190-5066 SP - insert 1-7 ST - Recommended practices for sponge, sharp, and instrument counts T2 - Same-Day Surgery TI - Recommended practices for sponge, sharp, and instrument counts UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107124371&site=ehost-live&scope=site VL - 24 ID - 942 ER - TY - JOUR AD - johnb@natn.org.uk AN - 12226951 AU - Beesley, J. DA - Jul DP - NLM ET - 2002/09/14 IS - 7 KW - Female Foreign Bodies/*prevention & control *Guidelines as Topic Humans Male Needles/adverse effects Perioperative Nursing/*standards/trends Postoperative Complications/*prevention & control Primary Prevention/*standards Quality of Health Care Surgical Instruments/adverse effects United Kingdom LA - eng N1 - Beesley, John Journal Article England Br J Perioper Nurs. 2002 Jul;12(7):238-9. PY - 2002 SN - 1467-1026 (Print) 1467-1026 SP - 238-9 ST - Recognized standards and recommended guidelines for the swab, instrument and needle count T2 - Br J Perioper Nurs TI - Recognized standards and recommended guidelines for the swab, instrument and needle count VL - 12 ID - 40 ER - TY - JOUR AB - BACKGROUND: Eosinophilic oesophagitis (EoE) is a chronic, inflammatory condition of the oesophagus, characterised by intermittent dysphagia, food bolus obstruction (FBO) and histologically proven, eosinophil-mediated inflammation. EoE is identified in up to 50% of FBO presentations. OBJECTIVE: To evaluate the management of patients presenting with FBO to our centre against current clinical guidelines. DESIGN: A retrospective analysis of acute FBO was performed between January 2008 and August 2014. Patients were identified using the ICD 10 code T18.1, 'foreign body in oesophagus' in their electronic discharge document. Data were collected on admitting specialty, previous FBO, endoscopy findings, biopsy sites and findings, eosinophil count and diagnosis of EoE. RESULTS: 310 acute episodes of FBO were included in the final study cohort. 202 (65.2%) flexible oesophagogastroduodenoscopies (OGDs) were performed, with 50 (34.5%) of those occurring in those admitted under ENT (n=145), versus 28 (93.3%) and 124 (91.9%) in general medicine (n=30) and surgery (n=135), respectively. 80 (39.6%) had oesophageal biopsies taken, and 21 novel diagnoses of EoE were made (26.3% biopsy-proven rate). Five (23.8%) of the novel diagnoses had a formal eosinophil count included in the histopathology report, and eight (38.1%) had up to three previous OGDs that had not diagnosed their condition of EoE. CONCLUSION: Our study highlights wide variation in adherence to the guidelines for the management of FBO depending on admitting specialty. We advocate an FBO protocol involving single specialty management, flexible OGD, ≥6 biopsies from the upper and lower oesophagus, and standardisation of oesophageal biopsy reports with a formal eosinophil count. AD - University of Dundee School of Medicine, University of Dundee, Dundee, UK. Royal London Hospital, London, London, UK. Glasgow Royal Infirmary, Glasgow, Glasgow, UK. General Surgery, Ninewells Hospital, Dundee, UK. AN - 31886777 AU - Ntuli, Y. AU - Bough, I. AU - Wilson, M. C2 - PMC6914293 DA - Jan DO - 10.1136/flgastro-2019-101176 DP - NLM ET - 2019/12/31 IS - 1 KW - dysphagia eosinophilic oesophagitis food bolus LA - eng N1 - 2041-4145 Ntuli, Yevedzo Orcid: 0000-0003-0612-4330 Bough, Isabelle Wilson, Michael Journal Article Frontline Gastroenterol. 2020 Jan;11(1):11-15. doi: 10.1136/flgastro-2019-101176. Epub 2019 Apr 29. PY - 2020 SN - 2041-4137 (Print) 2041-4137 SP - 11-15 ST - Recognising eosinophilic oesophagitis as a cause of food bolus obstruction T2 - Frontline Gastroenterol TI - Recognising eosinophilic oesophagitis as a cause of food bolus obstruction VL - 11 ID - 238 ER - TY - JOUR AB - The occurrence of peritoneal loose bodies has been known for hundreds of years. Although rarely, they attain a diameter of more than 5 cm and are then named “giant” peritoneal bodies (gPLBs). Even these huge peritoneal bodies are generally symptom free, but may be linked with chronic symptoms like abdominal pain or discomfort. Many a times, these gPLBs are misinterpreted as intraabdominal tumors or foreign bodies and unnecessary surgical interventions are carried out. We report a rare case of a 75-year-old male, who presented to our tertiary care center emergency department with history of chronic intermittent abdominal discomfort with acute diarrhea and peri-anal pain. Contrast enhanced computed tomography of the abdomen and pelvis revealed round to oval mass in the pelvis measuring 6.2 cm × 5.8 cm. On laparoscopy, a hard, free floating object with the appearance of a boiled egg could just be scooped out from the pelvis. The postoperative pathological examination revealed laminated strands of hyalinized fibro collagenous tissue with central fat necrosis confirming the diagnosis of gPLB. Postoperative period was uneventful. Peritoneal bodies are rare intraabdominal bodies which are either detected incidentally or present with vague symptoms and require interdisciplinary management. © 2020 AD - Department of Clinical Imaging and Interventional Radiology, Apollo Gleneagles Hospitals, Kolkata, India Institute of Gastrosciences and Liver, Apollo Gleneagles Hospitals, Kolkata, India Department of Urology, Apollo Gleneagles Hospitals, Kolkata, India Department of Pathology, Apollo Gleneagles Hospitals, Kolkata, India AU - Dhoot, N. M. AU - Afzalpurkar, S. AU - Goenka, U. AU - Mahendra, V. AU - Khan, E. M. AU - Sutradhar, A. AU - Goenka, M. DB - Scopus DO - 10.1016/j.radcr.2020.06.050 IS - 10 KW - Boiled egg Fibro collagenous tissue Free floating Giant Peritoneal body M3 - Article N1 - Export Date: 10 November 2020 PY - 2020 SP - 1895-1900 ST - A rare peritoneal egg: Case report with literature review T2 - Radiology Case Reports TI - A rare peritoneal egg: Case report with literature review UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85089508170&doi=10.1016%2fj.radcr.2020.06.050&partnerID=40&md5=71a2d64b6c316d46941d54a31d054116 VL - 15 ID - 954 ER - TY - JOUR AB - Objective: Ethyl acetate poisoning is rarely reported and is of low toxicity. Mucosal irritation and central nervous system (CNS) depression in high concentration is most commonly described. We present a case of ethyl acetate poisoning in a patient who required surgery due to foreign body formation. Case report: A 57-year-old female presented to the emergency department (ED) after a suicide attempt with ethyl acetate ingestion (about 200 mL) thirty minutes earlier. The initial vital signs were all within normal ranges and the initial symptom was vomiting. No nasogastic (NG) tube irrigation or activated charcoal were given due to low toxicity. The initial laboratory data including complete blood count, differential count, creatinine, sodium, potassium, and alanine transaminase were all within normal range. However, the patient became drowsy with respiratory distress due to stridor one hour after arrival. Emergency intubation was then performed for airway protection and desaturation followed by NG insertion for decompression. She was then admitted to intensive care unit. She was extubated 4 days later in a stable condition but during attempted removal it became clear that her NG tube was stuck in the stomach. Panendoscopy (PES) was then performed and showed a gastric foreign body attached to NG tube with hard content. The foreign body could not be removed via PES. Surgical intervention for foreign body removal was performed the next day. The patient recovered well after surgery and was discharged after 14 days in hospital. We then did a small experiment and put both a polyvinylchloride (PVC) NG tube and a silicon NG tube in ethyl acetate solution. Six hours later, the PVC NG tube was dissolved and the silicon NG was intact. When we mixed ethyl acetate with hydrochloric acid to mimic the gastric environment, some suspended solid materials formed and attached to NG tube. Conclusion: Ethyl acetate is of low toxicity with few cases reported; however, it can lead to formation of a hard solid foreign body in the stomach and cause obstruction. In addition, PVC NG tubing can dissolve in ethyl acetate solution. Hence, we recommend using silicon NG tubing for ethyl acetate ingestion if necessary. AD - C.K. Chen, Department of Emergency Medicines, Chang Gung Memorial Hospital, Taoyuan, Taiwan AU - Chen, C. K. DB - Embase DO - 10.3109/15563650.2015.1024953 IS - 4 KW - poison acetic acid ethyl ester silicon polyvinylchloride creatinine hydrochloric acid sodium potassium activated carbon alanine aminotransferase intoxication European nasogastric tube foreign body human patient toxicity surgery irrigation (agriculture) ingestion stomach vital sign emergency ward blood cell count laboratory suspended particulate matter suicide attempt intensive care unit decompression fatty acid desaturation case report protection airway tube intubation emergency vomiting stridor hospital respiratory distress environment solid obstruction female central nervous system depression LA - English M3 - Conference Abstract N1 - L71904205 2015-06-05 PY - 2015 SN - 1556-3650 SP - 317 ST - A rare complication of ethyl acetate poisoning T2 - Clinical Toxicology TI - A rare complication of ethyl acetate poisoning UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71904205&from=export http://dx.doi.org/10.3109/15563650.2015.1024953 VL - 53 ID - 431 ER - TY - JOUR AB - Introduction: Meckel's diverticulum is the most common congenital lesion of the small intestine. The incidence varies between 0.5% and 2% Biliary stents can be used for the treatment of patients with bile duct complications. Intestinal perforation due migrated stents is a very rare and life threatening complication. “Perforation of the Meckel diverticulum due to stent” and no case was found in the literature. For this reason, our case has been identified as the first case seen in the literature. Case presentation: A 20 year old male patient liver transplantation was performed from a live donor. 3 years ago The patient presented at our clinic with abdominal pain, nausea and vomiting that has been present for 2 days. Abdominal computed tomography showed a foreign body in the small intestines Patient was operated in emergency conditions. Meckel Diverticulum 40 cm proximal to the ileocecal valve and a biliary drainage catheter perforating the diverticule was seen Meckel's diverticulum was excised, primary repair was performed, Postoperative recovery was uneventful. Discussion: Complication rates due to a biliary stent range between 8–10% with a mortality below 1% (Konstantinidis et al. [1]). The most feared complication due to a biliary stent is stent migration. The perforation rate due to stent migration is below 1%. It most commonly occurs in the duodenum. Patients with stent related perforations are surgically managed as other GIS perforations. Conclusions: Perforation due to stent migration should also be considered in differential diagnosis in patients with a biliary stent and Acute Abdomen. © 2018 AD - Cukurova University, Department of General Surgery, Adana, Turkey AU - Topal, U. AU - Ülkü, A. AU - Sarıtaş, A. G. AU - Akçam, A. T. DB - Scopus DO - 10.1016/j.ijscr.2018.09.034 KW - Biliary stent migration Liver transplantation Meckel diverticule M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 SP - 35-38 ST - A rare complication in a liver transplant patient: Meckel diverticulum perforation due to biliary stent T2 - International Journal of Surgery Case Reports TI - A rare complication in a liver transplant patient: Meckel diverticulum perforation due to biliary stent UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85055252168&doi=10.1016%2fj.ijscr.2018.09.034&partnerID=40&md5=a95aeac9405e49738200470da536e861 VL - 53 ID - 1100 ER - TY - JOUR AB - The accumulation of undigested foreign bodies or nutrients in the gastrointestinal tract forming a conglomeration is called a bezoar. Bezoars are referred to according to the foreign bodies that constitute their core: phytobezoar (fibres or seeds of vegetables and fruits); trichobezoar (hair); lactobezoar (remnants of milk) and lithobezoar (rock or similar substances). Although they can be found in any part of the gastrointestinal system, the stomach is the most common site. Primary colonic bezoar is an exceptionally rare situation. Up until 2007, only four colonic lithobezoars had been reported in the literature. This report aims to present the clinical and surgical features of a 4-year-old male patient with a previous history of pica and iron deficiency anaemia, who underwent pebble extraction from the colon after being diagnosed with partial intestinal obstruction. AD - Department of Pediatric Surgery, School of Medicine, Zonguldak Karaelmas University, Kozlu 67600 Zonguldak, Turkey AU - Numanoǧlu, K. V. AU - Tatli, D. DB - Scopus DO - 10.1136/emj.2007.056812 IS - 5 M3 - Article N1 - Cited By :20 Export Date: 10 November 2020 PY - 2008 SP - 312-313 ST - A rare cause of partial intestinal obstruction in a child: Colonic lithobezoar T2 - Emergency Medicine Journal TI - A rare cause of partial intestinal obstruction in a child: Colonic lithobezoar UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-43149108872&doi=10.1136%2femj.2007.056812&partnerID=40&md5=94eadf5a2c43fc1f030cbab35014890a VL - 25 ID - 1530 ER - TY - JOUR AB - The use of mesh has become the gold standard in hernia operations recently due to advantages such as lower recurrence rates, lower post-surgical pain and earlier return to work. Plug mesh application, first described by Robins and Rutkow [Robbins AW, Rutkow IM (1993) The mesh-plug hernioplasty. Surg Clin North Am 73:501-512], is a popular method of hernia repair. Although rare, there may be complications of surgery using plug mesh. This report presents a case of mechanic bowel obstruction due to mesh migration, 3 years after a left inguinal hernia repair with plug mesh method. © 2011 Springer-Verlag. AD - Department of General Surgery, Military Hospital, 30000 Hakkari, Turkey Military Hospital, AǧrI, Turkey Department of General Surgery, Haydarpasa Training Hospital, Gulhane Military Medical Academy, Istanbul, Turkey AU - Yilmaz, I. AU - Karakaş, D. O. AU - Sucullu, I. AU - Ozdemir, Y. AU - Yucel, E. DB - Scopus DO - 10.1007/s10029-011-0867-0 IS - 2 KW - Inguinal hernia Mechanical bowel obstruction Plug mesh M3 - Article N1 - Cited By :15 Export Date: 10 November 2020 PY - 2013 SP - 267-269 ST - A rare cause of mechanical bowel obstruction: Mesh migration T2 - Hernia TI - A rare cause of mechanical bowel obstruction: Mesh migration UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84880698200&doi=10.1007%2fs10029-011-0867-0&partnerID=40&md5=9ed538e4d8f787af3690244132be6081 VL - 17 ID - 1323 ER - TY - JOUR AB - Introduction Biliary stent migration (proximal or distal) occurs in 6% of all cases. The majority of these migrating stents are passing through the intestine, without causing any complications. Usually when a stent migration occurs, endoscopic retrieval is the proper treatment option, except in case of complications when surgical removal is the only treatment option. This report presents a case of a biliary stent which migrated and caused a sigmoid colon perforation. Presentation of case A 75 years old female patient presented to the emergency department with diffuse abdominal pain, nausea and vomiting. Clinical examination showed distended abdomen and signs of peritoneal irritation. CT scan of the abdomen revealed free gas and fluid in the left iliac fossa, as well as a foreign body penetrating the sigmoid colon. Emergency laparotomy was performed. A plastic stent was found perforating the sigmoid colon through a diverticulum. The rest of the sigmoid colon was intact presenting only uncomplicated diverticula. Hartmann's operation was performed, involving the diseased segment, together with part of the descending colon due to profound diverticulosis. Patient's post-surgical course was uneventful and was discharged on postoperative day 10. Discussion Migration of a biliary stent can cause life-threatening complications such as perforation of the intestine and peritonitis. The migration of the stent from the biliary tree may be mostly asymptomatic except in cases of intestinal perforation that immediate surgery is the proper treatment option. On the other hand, even in cases of benign lesions of the bile duct, the stent should be removed immediately after dislocation in order to reduce the risk of secondary complications such as obstruction, infection or perforation. Conclusion In cases of non-complicated stent migration endoscopic retrieval is the indicated treatment. In patients who suffer serious complications due to stent dislocation, emergency surgery may be the proper treatment option. © 2017 The Author(s) AD - Department of Surgery, Sismanoglion General Hospital, Sismanoglou 1–P.O. BOX 15126, Athens, Greece AU - Siaperas, P. AU - Ioannidis, A. AU - Skarpas, A. AU - Angelopoulos, A. AU - Drikos, I. AU - Karanikas, I. DB - Scopus DO - 10.1016/j.ijscr.2017.01.016 KW - Biliary stents Hartmann's procedure Intestinal perforation Stent migration M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2017 SP - 83-85 ST - A rare cause for Hartmann's procedure due to biliary stent migration: A case report T2 - International Journal of Surgery Case Reports TI - A rare cause for Hartmann's procedure due to biliary stent migration: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85009961986&doi=10.1016%2fj.ijscr.2017.01.016&partnerID=40&md5=1d6955fd00dc9bb9946ddca2c9b630bf VL - 31 ID - 1160 ER - TY - JOUR AB - 24 year old female with no past medical history was admitted for intractable nausea and vomiting for two days. Patient has history of chronic marijuana use and reported multiple episodes of nausea with vomiting occurring after smoking marijuana for 48 hours. She also reported severe retching with these episodes. She has a known history of recurrent episodes of nausea and vomiting with long standing marijuana use. She denied any recent travel, ill contacts, fever, hematemesis, alcohol ingestion, and foreign body ingestion. She denied any prior surgeries or home medications. Her labs including complete blood count, comprehensive metabolic profile, lipase, amylase, urinalysis, and pregnancy test were unremarkable. Urine drug screen was positive for marijuana. CT scan of the abdomen was performed which revealed air in the gastric wall consistent with gastric emphysema. No evidence of perforation was seen. Surgery was consulted and patient was managed conservatively with supportive care and antibiotics. The patient improved clinically with subsequent improvement on repeat radiographic imaging. Gastric emphysema, seen when intramural air accumulates within the stomach wall, is a rare finding with 18 reported cases in literature. The acidic environment of the stomach creates a protective mucosal barrier preventing air penetration. However, there are several proposed mechanisms that can disrupt the mucosal barrier including infections, increased intragastric pressure, foreign body ingestion, and dissection of air from the mediastinum. There are 2 variants of intramural gas within the stomach wall: emphysematous gastritis and gastric emphysema. Emphysematous gastritis is proposed to have an infectious etiology and usually presents with an acute abdomen with a mortality rate reported up to 60%. Gastric emphysema is proposed to have a traumatic/mechanical/inflammatory etiology causing air to dissect through the stomach wall. Gastric emphysema tends to have a more benign clinical course and typically resolves with conservative management. Gastric emphysema is a rare finding with significant clinical importance. We report an unusual case of gastric emphysema secondary to excessive retching and vomiting resulting from cannabinoid hyperemesis syndrome. A favorable prognosis is seen with early recognition and appropriate medical management. (Figure Presented). AD - S.T. Kumar, Richmond University Medical Center, Edison, NJ, United States AU - Kumar, S. T. AU - Nazli, A. AU - Vadada, D. AU - Kalman, J. AU - Yiachos, C. AU - Prakash, S. DB - Embase DO - 10.1038/ajg.2016.375 KW - alcohol amylase antibiotic agent cannabis endogenous compound triacylglycerol lipase acute abdomen adult blood cell count cannabis use case report computer assisted tomography conservative treatment dissection emphysema female fever foreign body gastritis hematemesis human human tissue hyperemesis gravidarum imaging infection ingestion mediastinum mortality rate patient history of surgery perforation pregnancy test prognosis recognition retching smoking stomach pressure stomach wall surgery travel urinalysis young adult LA - English M3 - Conference Abstract N1 - L612869685 2016-11-10 PY - 2016 SN - 1572-0241 SP - S1105-S1106 ST - A rare case of gastric emphysema secondary to cannabinoid hyperemesis syndrome T2 - American Journal of Gastroenterology TI - A rare case of gastric emphysema secondary to cannabinoid hyperemesis syndrome UR - https://www.embase.com/search/results?subaction=viewrecord&id=L612869685&from=export http://dx.doi.org/10.1038/ajg.2016.375 VL - 111 ID - 395 ER - TY - JOUR AD - Division of Gastroenterology, Department of Internal Medicine, Shuang-Ho Hospital, Taipei Medical University, New Taipei City, Taiwan Division of Pathology, Shuang-Ho Hospital, Taipei Medical University, New Taipei City, Taiwan AU - Lin, C. AU - Lee, W. AU - Lee, I. DB - Scopus DO - 10.1016/j.cgh.2012.08.023 IS - 1 M3 - Article N1 - Export Date: 10 November 2020 PY - 2013 SP - e1-e2 ST - A Rare Case of Esophageal Submucosal Angiofibroma Resected Completely by Endoscopic Submucosal Dissection T2 - Clinical Gastroenterology and Hepatology TI - A Rare Case of Esophageal Submucosal Angiofibroma Resected Completely by Endoscopic Submucosal Dissection UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84870919375&doi=10.1016%2fj.cgh.2012.08.023&partnerID=40&md5=487686ee01b7b7978f6586ca71f0a0e6 VL - 11 ID - 1341 ER - TY - JOUR AB - Introduction: Aortoesophageal fistula (AEF) in children is rare and results in very high mortality. Foreign body ingestions remain the commonest cause of AEF in children. Case Report: A two-year-old girl child presented with massive hematemesis, fresh blood per rectum, and melena for 2 h. No previous history of massive hematemesis. One day back, there was ingestion of meat with bone piece 2 days back, felt pain in chest for 1 day. On examination, the child was restless and irritable. She had features s/o rate of 140 per minute and blood pressure of 70/ 40 mmHg. Systemic examination was unremarkable. The child was resuscitated with fluids and packed red blood cells (PRBCs). Bleeding continued resulting in progressive worsening of hemodynamic status over the next few hours. Intubated for prevention of aspiration and put on support. The preliminary reports revealed hemoglobin of 3.2 g/dl, total leucocyte count of 18,500/mm3, platelet count of 250,000/mm3. Upper GI endoscopy showed rounded ulcer of around 7 × 7mm diameter with overturned margins and clot just above GE junction. Bleeding started while observing it. Hemostatic procedures failed. Resuscitative and ionotropes started. Patient referred to pediatric surgeon, CECT thorax planned, but due to active bleed and shock could not be done, the child was taken up for emergency thoracotomy. AEF usually results in a very high mortality. Many succumb to the bleed, neurological deficit, and spinal ischemia developed during repair of aortic defect. In our case, the child could not survive post surgery. AD - V. Sharma, Departments of Gastroenterology, Jaipur, India AU - Sharma, V. AU - Sharma, R. AU - Sharma, S. D. DB - Embase DO - 10.1111/jgh.13540 KW - endogenous compound hemoglobin aorta aortoesophageal fistula aspiration blood pressure bone case report child emergency endoscopy erythrocyte female gastroesophageal junction girl hematemesis human ingestion leukocyte count liquid melena mortality pediatric surgeon preschool child rectal drug administration spinal cord ischemia surgery thoracotomy thorax pain platelet count ulcer LA - English M3 - Conference Abstract N1 - L612985130 2016-11-07 PY - 2016 SN - 1440-1746 SP - 296-297 ST - A rare case of aorto-esophageal fistula in a child presenting with massive hematemesis T2 - Journal of Gastroenterology and Hepatology (Australia) TI - A rare case of aorto-esophageal fistula in a child presenting with massive hematemesis UR - https://www.embase.com/search/results?subaction=viewrecord&id=L612985130&from=export http://dx.doi.org/10.1111/jgh.13540 VL - 31 ID - 387 ER - TY - JOUR AB - Purpose: To compare the sutureless 23 gauge (G) pars plana vitrectomy (PPV) with the 20G PPV regarding inflammation, visual outcome and patient comfort. Methods: We included 100 patients with symptomatic macular hole or macular pucker, scheduled for vitrectomy in this prospective, randomized, controlled, mono-center clinical trial which followed the tenets of the Declaration of Helsinki. Patients were randomized 1:1 either to 20G PPV (n=51) or 23G PPV (n=49). All eyes underwent standard 20G or 23G PPV with membrane peeling. Primary endpoint was change in aqueous humor flare 3 weeks after surgery compared to baseline. Flare was measured with the FM-500 Laser Flare-Cell Meter (Kowa Company, Ltd, Tokyo, Japan) and expressed as photon counts per millisecond (pc/ms). Secondary outcome measures were postoperative discomfort measured with a visual analog scale, best-corrected visual acuity, postoperative intra ocular pressure (IOP), number of complications and duration of surgery. Results: There was no significant difference in change of aqueous humor flare between the groups (20G:3.5 ±9.5 pc/ms, 23G:2.3 ±13.2 pc/ms, p= 0.452). Only in the per protocol set (31 eyes in each group), a lower increase in aqueous flare was observed after 23G PPV (20G:1.9± 6.7 pc/ms, 23G:-0.1±4.8 pc/ms, p=0.039). Postoperative IOP was lower after 23G PPV (20G:16.9±8.2 mmHg, 23G:12.5±6.2 mmHg, p=0.005), but the rate of postoperative hypo- or hypertension did not differ between the groups (p=0.207). The gain in ETDRS letters 3 weeks after surgery was higher after 23G PPV (20G:4.2±10.4, 23G:6.8±10.4, p=0.034), but showed no significant difference after 6 month (20G:11.0±13.5, 7.3±15.6, p=0.588). The mean duration of surgery was shorter in the 23G group (20G:29 ±6 min, 23 G:20±6 min, p<0.0001) and patients after 23G PPV showed higher comfort (Foreign body sensation 20G:22±24, 23G:9 ±14, p=0.002; itching:20G:12±20, 23G:5±10, p=0.021). The rate of complications did not differ between the groups. Conclusions: The primary endpoint, a significant lower change in flare values in the 23G group three weeks after surgery, could not be reached, but the level of inflammation decreases faster after 23G PPV. Clear advantages of the 23G PPV are a shorter surgery time, faster visual recovery and a higher comfort in the early postoperative phase. These advantages must be seen in relation to the higher cost of the system. AD - P. Scholz, Department of Ophthalmology, University Hospital Cologne, Cologne, Germany AU - Scholz, P. AU - Müther, P. AU - Schiller, P. AU - Felsch, M. AU - Fauser, S. DB - Embase IS - 9 KW - adult aqueous humor best corrected visual acuity comfort complication conference abstract controlled study epiretinal membrane female foreign body gauge human hypertension inflammation intraocular pressure Japan laser flare cell meter major clinical study male operation duration outcome assessment pars plana vitrectomy photon postoperative period prospective study pruritus randomized controlled trial retina macula hole sensation visual analog scale LA - English M3 - Conference Abstract N1 - L628422820 2019-07-11 PY - 2018 SN - 1552-5783 ST - A randomized controlled clinical trial comparing 20 gauge and 23 gauge vitrectomy for patients with macular hole or macular pucker T2 - Investigative Ophthalmology and Visual Science TI - A randomized controlled clinical trial comparing 20 gauge and 23 gauge vitrectomy for patients with macular hole or macular pucker UR - https://www.embase.com/search/results?subaction=viewrecord&id=L628422820&from=export VL - 59 ID - 342 ER - TY - JOUR AB - One encounters a variety of radiopaque foreign objects when reviewing plain film radiographs of the abdomen. Recognizing such devices can offer important clues about a patient's medical history. Accordingly, intrauterine contraceptive devices (IUCD), tubal sterilization, varicoceles, inferior vena cava (IVC) filtration, and vaginal pessaries are discussed with reference made to an IUD, tubal sterilization clips, embolization coils for bilateral varicoceles, an IVC filter, and a vaginal pessary in five attached anteroposterior radiographs of the lower abdomen and pelvis for five different patients. IUCDs confer long-term, passive, reversible, and inexpensive protection against unwanted pregnancy. They may, however, induce menstrual complications as well as an increased risk of pelvic inflammatory disease and ectopic pregnancy. They can also be spontaneously expelled from the uterus without being noticed by the client. An IUCD increases the risk of spontaneous abortion unless removed in cases where intrauterine pregnancy occurs. Complications at the time of insertion include pain, syncope, and uterine perforation. Tubal sterilization is an effective, though largely irreversible method of contraception. Complications include an increased risk of ectopic gestation in the event of pregnancy and the usual risks of hemorrhage, infection, injury to adjacent structures, and anesthesia-related complications. A varicocele is a dilation of the pampiniform venous plexus of the scrotum. They are more often unilateral than bilateral, occurring in up to 20% of men most often on the left side. Although most cases are probably insignificant, varicoceles can decrease sperm count and motility and cause abnormal morphology. Correction of varicoceles has been shown to improve sperm quality and can increase the chances of fertility. Percutaneous venous embolization techniques have recently been developed to that end. Procedural risks include perforation of the vein, intimal dissection, inadvertent embolization of vessels via collateral channels, and reactions to contrast media. IVC filters are a feasible alternative treatment for deep venous thrombosis and pulmonary embolism among patients in whom anticoagulants are contraindicated or for those in whom anticoagulation therapy has failed. Introduced via the femoral or jugular veins, they are permanent metallic devices placed within the lumen of the IVC to filter thrombi which migrate from the deep veins of the lower extremities. Contraindications to IVC filter insertion include severe coagulopathy and thrombosis involving all venous access routes, while complications include hematoma at the insertion site, migration or tilting of the device due to poor anchoring in the IVC wall, and vena cava obstruction. A pessary is a prosthetic device used to support pelvic structures when their natural support is lacking. They are usually made of plastic or rubber and inserted into the vagina to aid in the non-operative treatment of uterine prolapse, proctoceles, and cystoceles. They must be properly fitted and removed every few months for cleaning. eng AD - Mount Sinai Hospital in Toronto. AN - 8219857 AU - Margolis, M. AU - McLennan, M. K. DA - Oct DP - NLM ET - 1993/10/01 KW - Adult Aged Aged, 80 and over Embolization, Therapeutic/instrumentation Female Foreign Bodies/diagnostic imaging Humans Intrauterine Devices Male Pelvis/diagnostic imaging Pessaries *Radiography, Abdominal Sterilization, Tubal/instrumentation Vena Cava Filters Biology *Case Histories *Clips Contraception Contraceptive Methods *Equipment And Supplies Examinations And Diagnoses Family Planning Female Sterilization *Genital Effects, Male Genitalia Genitalia, Male *Hemic System *Infertility--men *Iud *Physical Examinations And Diagnoses Physiology Reproduction Sterilization, Sexual *Teaching Materials *Tubal Ligation Tubal Occlusion Urogenital System LA - eng N1 - Margolis, M McLennan, M K Case Reports Journal Article Canada Can Fam Physician. 1993 Oct;39:2113, 2283-4. PY - 1993 SN - 0008-350X (Print) 0008-350x SP - 2113, 2283-4 ST - Radiology rounds. Intrauterine contraceptive device T2 - Can Fam Physician TI - Radiology rounds. Intrauterine contraceptive device VL - 39 ID - 21 ER - TY - JOUR AB - Titanium (Ti) screw has excellent mechanical property, and osseointegration capacity. However, they require surgery for removal. In contrast, polymer screws are resorbable, but they have poor mechanical properties. In this research, magnesium alloy screws (WE43: Mg-Y-Nd-Zr) that have advantages of titanium and polymer were manufactured. In addition, to increase biocompatibility and control degradation rate, the Mg alloy was coated with hydroxyapatite (HA). Torsion test and corrosion test were performed in vitro. For clinical, radiological and histological evaluation, on the eight rabbits, two HA-coated screws were installed in left tibia, and two noncoated screws were installed in right tibia. Each four rabbits were sacrificed 6 and 12 weeks postoperatively. For hematological evaluation, the same type of screws were installed on both legs. Complete blood count (CBC), Mg2+ concentrate were sampled from the ear central artery on the operation day for a control point, and at 1, 2, 4, 6, 8, and 12 weeks. Mg alloy screws have no differences of biocompatibility according to the HA coating. However, resorption of screw was slower in case of the HA coating. The hematological problem related releasing of Mg was not found. The results suggest that Mg alloy screws have feasibility for clinical application. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 1636–1644, 2017. © 2016 Wiley Periodicals, Inc. AD - Department of Oral and Maxillofacial Surgery, Clinical Trial Center, Seoul National University Dental Hospital, Seoul, South Korea Department of Oral and Maxillofacial Surgery, Korea University Medical Center, Guro Hospital, Seoul, South Korea Department of Oral and Maxillofacial Surgery, Dongtan Sacred Heart Hospital, Hallym University Medical CenterKyonggi-do, South Korea Department of Oral and Maxillofacial Surgery, Kyunghee University Dental Hospital, Seoul, South Korea Department of Material Science and Engineering, Seoul National University, Seoul, South Korea AU - Lim, H. K. AU - Byun, S. H. AU - Lee, J. Y. AU - Lee, J. W. AU - Kim, S. M. AU - Lee, S. M. AU - Kim, H. E. AU - Lee, J. H. DB - Scopus DO - 10.1002/jbm.b.33703 IS - 6 KW - biocompatibility bioresorbable screw HA coating magnesium magnesium alloy (WE43) M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2017 SP - 1636-1644 ST - Radiological, histological, and hematological evaluation of hydroxyapatite-coated resorbable magnesium alloy screws placed in rabbit tibia T2 - Journal of Biomedical Materials Research - Part B Applied Biomaterials TI - Radiological, histological, and hematological evaluation of hydroxyapatite-coated resorbable magnesium alloy screws placed in rabbit tibia UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84969964436&doi=10.1002%2fjbm.b.33703&partnerID=40&md5=249d8f5266fffb2cacf6f31b342bd176 VL - 105 ID - 1129 ER - TY - JOUR AB - A 77-year-old edentulous man presented to the accident and emergency department with a sudden onset of sharp right-sided abdominal pain. The patient reported a change in his bowel habit with constipation over a 6 month period but did not report any significant choking event or ingestion of a foreign body in the preceding months. On examination the patient was maximally tender with guarding over McBurneys point. CT scan showed an abnormal segment of distal ileum with a 3 cm high attenuation focus which had penetrated the bowel wall. At laparotomy the patient was found to have a perforation of his distal ileum caused by an ingested toothpick. Patients wearing dental plates or dentures are at higher risk of toothpick ingestion due to impaired palatal sensation. CT scanning, in the appropriate setting, may aid diagnosis and lower operator risk of sharp related injury at the time of operation. AD - Department of General Surgery, Ulster Hospital, Belfast, United Kingdom AU - Mark, D. AU - Ferris, K. AU - Martel, G. AU - Mulholland, K. C7 - 009869 DB - Scopus DO - 10.1136/bcr-2013-009869 M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2013 ST - Radiological diagnosis of a small bowel perforation secondary to toothpick ingestion T2 - BMJ Case Reports TI - Radiological diagnosis of a small bowel perforation secondary to toothpick ingestion UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84884263144&doi=10.1136%2fbcr-2013-009869&partnerID=40&md5=7067b3dbfdc2b903de164f3d69f733ef ID - 1312 ER - TY - JOUR AB - BACKGROUND: Counts are the commonest method used to ensure that all sponges and neuropatties are removed from a surgical site before closure. When the count is not reconciled, plain radiographs of the operative site are taken to determine whether the missing patty has been left in the wound. The purpose of this study was to describe the detectability of commonly used neuropatties in the clinical setting using digital technologies. METHODS: Neuropatties were implanted into the anterior and posterior cranial fossae and the thoracolumbar extradural space of a mature male cadaver. Four neuropatty sizes were used: 3 × 1 in, 2 × ½ in, ½ × ½ in, and ¼ × ¼ in. Neuropatties, with size and location chosen at random, were placed in the surgical sites and anteroposterior/posterior-anterior and lateral radiographs were taken using standard portable digital radiographic equipment. Six clinicians reviewed the digital images for the presence or absence of neuropatties. The readers were not aware of the number and size of the patties that were included in each image. RESULTS: The detectability of neuropatties is dependent on the size of the neuropatty's radiopaque marker and the operative site. Neuropatties measuring 2 × ½ in and 3 × 1 in were detected reliably regardless of the operative site. ¼ × ¼ in neuropatties were poorly detected by neurosurgeons and radiologists in all three operative sites. Readers of various experience and background were similar in their ability to detect neuropatties under these conditions. CONCLUSIONS: Under simulated operating room conditions and using currently available neuropatties and plain radiograph imaging technology, small ¼-in and ½-in neuropatties are poorly visible/detectable on digital images. AD - Department of Surgery, University of British Columbia and British Columbia Children's Hospital, Vancouver, British Columbia, Canada. Department of Radiology, British Columbia Children's Hospital, Vancouver, British Columbia, Canada. Department of Radiology, British Columbia Children's Hospital, Vancouver, British Columbia, Canada; Department of Radiology, University of British Columbia, Vancouver, British Columbia, Canada. Department of Surgery, University of British Columbia and British Columbia Children's Hospital, Vancouver, British Columbia, Canada. Electronic address: dcochrane@cw.bc.ca. AN - 25818890 AU - Luo, W. T. AU - Almack, R. AU - Mawson, J. B. AU - Cochrane, D. D. DA - Aug DO - 10.1016/j.wneu.2015.03.032 DP - NLM ET - 2015/03/31 IS - 2 KW - Adult Cadaver Foreign Bodies/*diagnosis/etiology Humans Male Models, Anatomic Neurosurgical Procedures/*adverse effects/instrumentation Observer Variation Radiography Sensitivity and Specificity Skull/*diagnostic imaging/surgery Spine/*diagnostic imaging/surgery *Surgical Sponges Cadaver model Foreign body Imaging Neuropatty Radiopaque Retained LA - eng N1 - 1878-8769 Luo, Wangjian Thomas Almack, Robert Mawson, John B Cochrane, David Douglas Journal Article United States World Neurosurg. 2015 Aug;84(2):405-11. doi: 10.1016/j.wneu.2015.03.032. Epub 2015 Mar 27. PY - 2015 SN - 1878-8750 SP - 405-11 ST - Radiographic Detectability of Retained Neuropatties in a Cadaver Model T2 - World Neurosurg TI - Radiographic Detectability of Retained Neuropatties in a Cadaver Model VL - 84 ID - 159 ER - TY - JOUR AB - BACKGROUND: A retained surgical item in patients (gossypiboma) is a persisting problem, despite consistent improvements and existing guidelines in counting instruments and sponges. Previous experiences with radiofrequency identification technology (RFID) tracking sponges show that it could represent an innovation, in order to reduce the criticism and increase the effectiveness during surgical procedures. We present an automated system that allows reduction of errors and improves safety in the operating room. METHODS: The system consists of 3 antennas, surgical sponges containing RFID tags, and dedicated software applications, with Wi-Fi real-time communication between devices. The first antenna provides the initial count of gauzes; the second a real-time counting during surgery, including the sponges thrown into the kick-bucket; and the third can be used in the event of uneven sponge count. The software allows management at all stages of the process. RESULTS: In vitro and in vivo tests were performed: the system provided excellent results in detecting sponges in patients' body. Hundred percent retained sponges were detected correctly, even when they were overlapped. No false positive or false negative was recorded. The counting procedure turned out to be more streamlined and efficient and it could save time in a standard procedure. CONCLUSIONS: The RFID system for sponge tracking was shown to be experimentally a reliable and feasible method to track sponges with a full detection accuracy in the operating room. The results indicate the system to be safe and effective with acceptable cost-effective parameters. AD - 1 University of Tor Vergata, Rome, Italy. 2 5-Emme Informatica Spa, Rome, Italy. 3 Sapienza University, Rome, Italy. 4 Istituto Superiore di Sanità, Rome, Italy. AN - 28178883 AU - Lazzaro, A. AU - Corona, A. AU - Iezzi, L. AU - Quaresima, S. AU - Armisi, L. AU - Piccolo, I. AU - Medaglia, C. M. AU - Sbrenni, S. AU - Sileri, P. AU - Rosato, N. AU - Gaspari, A. L. AU - Di Lorenzo, N. DA - Jun DO - 10.1177/1553350617690608 DP - NLM ET - 2017/02/10 IS - 3 KW - Animals Biomedical Engineering Computer Simulation Equipment Design *Foreign Bodies/diagnosis/prevention & control Humans Internet Phantoms, Imaging *Radio Frequency Identification Device Software Surgery, Computer-Assisted/*instrumentation/methods *Surgical Sponges Swine image-guided surgery simulation LA - eng N1 - 1553-3514 Lazzaro, Alessandra Corona, Arianna Iezzi, Luca Quaresima, Silvia Armisi, Luca Piccolo, Ilaria Medaglia, Carlo Maria Sbrenni, Sergio Sileri, Pierpaolo Rosato, Nicola Gaspari, Achille Lucio Di Lorenzo, Nicola Journal Article United States Surg Innov. 2017 Jun;24(3):268-275. doi: 10.1177/1553350617690608. Epub 2017 Feb 8. PY - 2017 SN - 1553-3506 SP - 268-275 ST - Radiofrequency-Based Identification Medical Device: An Evaluable Solution for Surgical Sponge Retrieval? T2 - Surg Innov TI - Radiofrequency-Based Identification Medical Device: An Evaluable Solution for Surgical Sponge Retrieval? VL - 24 ID - 189 ER - TY - JOUR AN - 106212945. Language: English. Entry Date: 20070112. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 10 KW - Radio Waves Retained Instruments -- Prevention and Control Surgical Count Procedure Surgical Sponges N1 - brief item; pictorial. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. NLM UID: 7600137. PY - 2006 SN - 0360-4039 SP - 35-35 ST - Radiofrequency technology: tracking down wayward sponges T2 - Nursing TI - Radiofrequency technology: tracking down wayward sponges UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106212945&site=ehost-live&scope=site VL - 36 ID - 883 ER - TY - JOUR AB - Purpose To evaluate the incidence and associated factors of pulmonary seed migration after parotid brachytherapy using a novel migrated seed detection technique. Methods and Materials Patients diagnosed with parotid cancer who underwent permanent parotid brachytherapy from January 2006 to December 2011 were reviewed retrospectively. Head and neck CT scans and chest X-rays were evaluated during routine follow-up. Mimics software and Geomagic Studio software were used for seed reconstruction and migrated seed detection from the original implanted region, respectively. Postimplant dosimetry analysis was performed after seeds migration if the seeds were still in their emitting count. Adverse clinical sequelae from seed embolization to the lung were documented. Results The radioactive seed implants were identified on chest X-rays in 6 patients. The incidence rate of seed migration in 321 parotid brachytherapy patients was 1.87% (6/321) and that of individual seed migration was 0.04% (6/15218 seeds). All migrated seeds were originally from the retromandibular region. No adverse dosimetric consequences were found in the target region. Pulmonary symptoms were not reported by any patient in this study. Conclusions In our patient set, migration of radioactive seeds with an initial radioactivity of 0.6–0.7 mCi to the chest following parotid brachytherapy was rare. Late migration of a single seed from the central target region did not affect the dosimetry significantly, and patients did not have severe short-term complications. This study proposed a novel technique to localize the anatomical origin of the migrated seeds during brachytherapy. Our evidence suggested that placement of seeds adjacent to blood vessels was associated with an increased likelihood of seed migration to the lungs. © 2017 American Brachytherapy Society AD - Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China Melbourne Dental School, University of Melbourne, Melbourne, Australia Murdoch Children's Research Institute, Melbourne, Australia Center of Digital Dentistry, Peking University School and Hospital of Stomatology; National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing, China Department of Stomatology, Fujian Provincial Hospital, Fuzhou, China AU - Fan, Y. AU - Huang, M. W. AU - Zhao, Y. J. AU - Gao, H. AU - Zhang, J. G. DB - Scopus DO - 10.1016/j.brachy.2017.08.007 IS - 6 KW - 3D reconstruction Brachytherapy Parotid Seed migration M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2017 SP - 1219-1224 ST - Radioactive seed migration following parotid gland interstitial brachytherapy T2 - Brachytherapy TI - Radioactive seed migration following parotid gland interstitial brachytherapy UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85029529907&doi=10.1016%2fj.brachy.2017.08.007&partnerID=40&md5=bc90611175dc0a2236981ef8745770c3 VL - 16 ID - 1115 ER - TY - JOUR AB - We report a 73-year-old female patient who underwent total hip arthroplasty for osteoarthritis of the right hip. An anteroposterior radiograph obtained 1 week after surgery showed an intra-articular striated foreign body. This was subsequently removed and found to be a radio-opaque marker of a surgical sponge that had been used during the operation. The patient made an uneventful recovery. In recent years, cases of retained surgical sponge after surgery have been reported occasionally. Counting surgical sponges and using sponges with radio-opaque markers are methods for preventing them from being accidentally left in situ. However, to our knowledge, there has been no report of retention of a surgical sponge radio-opaque marker at the operation site, appearing as a foreign body on an X-ray film. AD - Department of Orthopaedic Surgery, Gifu University School of Medicine, Gifu, Japan. ioritigers@yahoo.co.jp AN - 17906867 AU - Takigami, I. AU - Itoh, Y. AU - Itokazu, M. AU - Shimizu, K. DA - Oct DO - 10.1007/s00402-007-0469-6 DP - NLM ET - 2007/10/02 IS - 10 KW - Aged Arthroplasty, Replacement, Hip/*adverse effects Contrast Media Female *Foreign Bodies *Hip Joint Humans Osteoarthritis, Hip/*surgery *Surgical Sponges LA - eng N1 - 1434-3916 Takigami, Iori Itoh, Yoshiki Itokazu, Mansho Shimizu, Katsuji Case Reports Journal Article Germany Arch Orthop Trauma Surg. 2008 Oct;128(10):1167-8. doi: 10.1007/s00402-007-0469-6. Epub 2007 Sep 29. PY - 2008 SN - 0936-8051 SP - 1167-8 ST - Radio-opaque marker of a surgical sponge appearing as an intra-articular foreign body after total hip arthroplasty T2 - Arch Orthop Trauma Surg TI - Radio-opaque marker of a surgical sponge appearing as an intra-articular foreign body after total hip arthroplasty VL - 128 ID - 68 ER - TY - JOUR AN - 105574874. Language: English. Entry Date: 20090116. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 5 KW - Radio Frequency Identification Surgical Count Procedure -- Methods N1 - brief item. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PMID: NLM18993138. PY - 2008 SN - 0001-2092 SP - 815-815 ST - Radio-frequency system supplements sponge counting T2 - AORN Journal TI - Radio-frequency system supplements sponge counting UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105574874&site=ehost-live&scope=site VL - 88 ID - 881 ER - TY - JOUR AB - Radio-frequency (RF) tags are now being embedded in items such as surgical sponges, towels, and pads to reduce the chances that these objects will be left in patients after a procedure. Find out how--and how well--RF sponge-detection systems work, including our view of the two systems currently on the market: ClearCount Medical's SmartSponge System, which counts sponges in addition to detecting them. RF Surgical's RF Surgical Detection System, which is a detect-only system. AN - 18771206 DA - Jul DP - NLM ET - 2008/09/06 IS - 7 KW - Electronic Data Processing Foreign Bodies/diagnostic imaging Humans Medical Errors/*prevention & control Operating Rooms/organization & administration Postoperative Complications/prevention & control *Radio Waves Radiography *Surgical Sponges LA - eng N1 - Journal Article United States Health Devices. 2008 Jul;37(7):193-202. PY - 2008 SN - 0046-7022 (Print) 0046-7022 SP - 193-202 ST - Radio-frequency surgical sponge detection: a new way to lower the odds of leaving sponges (and similar items) in patients T2 - Health Devices TI - Radio-frequency surgical sponge detection: a new way to lower the odds of leaving sponges (and similar items) in patients VL - 37 ID - 82 ER - TY - JOUR AB - Use of gauze sponges that have been embedded with passive radio frequency identification (RFID) tags presents a high probability of reducing or eliminating instances of gossypiboma, or retained surgical sponge. The use of human counts during surgical operations, especially during instances where unexpected or emergency events occur, can result in errors where surgical instruments, most often gauze sponges, are retained within the patient's body, leading to complications at a later date. Implementation of an automatic inventory record system, for instance, RFID, may greatly reduce these incidences by removing the human factor and would improve patient safety by eliminating the current sponge count protocol. Experiments performed by placing RFID-labeled sponges within an animal and removing them have demonstrated that tags are at least partially readable inside the body cavity and fully readable once removed, suggesting the possibility of an automated sponge count system pending further development of this technology. © 2007 Springer Science+Business Media, LLC. AD - E. Jones, Department of Industrial Engineering, University of Nebraska, Lincoln, NE, United States AU - Rogers, A. AU - Jones, E. AU - Oleynikov, D. DB - Embase Medline DO - 10.1007/s00464-007-9308-7 IS - 7 KW - article biosafety clinical audit medical record priority journal radiofrequency retained instrument risk reduction surgical risk surgical sponge LA - English M3 - Article N1 - L47024770 2007-07-01 PY - 2007 SN - 0930-2794 1432-2218 SP - 1235-1237 ST - Radio frequency identification (RFID) applied to surgical sponges T2 - Surgical Endoscopy and Other Interventional Techniques TI - Radio frequency identification (RFID) applied to surgical sponges UR - https://www.embase.com/search/results?subaction=viewrecord&id=L47024770&from=export http://dx.doi.org/10.1007/s00464-007-9308-7 VL - 21 ID - 613 ER - TY - JOUR AB - A total of 57 male, 3-month old rats each received 6 implants in the subcutis of the back, each implant consisting of a PVC tube with two polyester-polyurethane sponges. After 1, 2, 3, 4, 6, 8, 12 and 16 weeks, the tubes were removed and the sponges were subjected to morphological, morphometric, chemical (DNA and collagen) autoradiographical and radiochemical examination. On the basis of the test results, it was established that in the particular form of induced tissue growth chosen three phases can bs distinguished: in the first phase which lasts till the end of the first week after implantation, an exudative inflammation arises. This is measurable by the high percental proportion of neutrophile granulocytes and the 3H-thymidine indices of the proliferating cells. The second phase, which lasts from the 2nd to the 4th week, was defined as the reparative phase. After the 4th week, we had a model of a chronic proliferative inflammation. At this time, and continuing until the end of the test period, the labelling index of the proliferating cells was clearly higher than that of unstimulated tissue. Because the duration of the separate phases can be exactly defined, this mcdel is particularly suitable for the testing of various pharmaceutical pxparation. © 1974 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. AD - Departnient of Pathology II of the Center for Biology, University of Ulm, Germany Departnient of Theoretical Medicine, University of Ulm, Germany AU - Paulini, K. AU - Körner, B. AU - Beneke, G. AU - Endres, R. DB - Scopus DO - 10.3109/03008207409152254 IS - 4 M3 - Article N1 - Cited By :19 Export Date: 10 November 2020 PY - 1974 SP - 257-264 ST - A quantitative study of the growth of connective tissue: Investigations on implanted polyester-polyurethane sponges T2 - Connective Tissue Research TI - A quantitative study of the growth of connective tissue: Investigations on implanted polyester-polyurethane sponges UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0016189057&doi=10.3109%2f03008207409152254&partnerID=40&md5=fbf3a3208b3ff5632ea5ed241717a203 VL - 2 ID - 1779 ER - TY - JOUR AB - Fourteen mature female New Zealand White rabbits underwent implantation of Simplex polymethylmethacrylate (PMMA) powder or particulate (average 67 μn) ultrahigh-molecular-weight polyethylene (UHMWPE) through a drill hole in the proximal right tibia. The left tibia functioned as a prepared but nonimplanted control. Animals were killed after 16 weeks. Histological examination of the bone-implant interface in the particulate PMMA group disclosed a florid foreign-body reaction with the presence of giant cells and histiocytes. The particulate UHMWPE group demonstrated positively bire-fringent UHMWPE fragments, rimmed by foreign-body giant cells and histiocytes, embedded in a loose connective tissue stroma. UHMWPE interfaces were thicker and contained more histiocytes and fibrocytes; PMMA interfaces contained more marrow cells and lymphocytes. This study underscores the importance of biomaterial debris in the process of aseptic loosening of cemented joint arthroplasties. © 1991 Springer-Verlag. AD - Division of Orthopaedic Surgery, Stanford University Medical Center, Stanford, 94305, Ca, United States Department of Pathology, University of Toronto, Princess Margaret Hospital, Toronto, Canada AU - Goodman, S. B. AU - Fornasier, V. L. AU - Keil, J. DB - Scopus DO - 10.1007/BF00395792 IS - 3 M3 - Article N1 - Cited By :15 Export Date: 10 November 2020 PY - 1991 SP - 123-126 ST - Quantitative comparison of the histological effects of particulate polymethylmethacrylate versus polyethylene in the rabbit tibia T2 - Archives of Orthopaedic and Trauma Surgery TI - Quantitative comparison of the histological effects of particulate polymethylmethacrylate versus polyethylene in the rabbit tibia UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025854648&doi=10.1007%2fBF00395792&partnerID=40&md5=a4fecf75e58b2dac5799c8ad3f2d367a VL - 110 ID - 1737 ER - TY - JOUR AB - The objective of the present study was to evaluate the quality and intensity of the tissue response to two synthetic hydroxyapatites implanted in critical defects in the skulls of rats. Sixty animals were divided into three experimental groups: I (control), II (HA-1 = HA with 28% crystallinity) and III (HA-2 = HA with 70% crystallinity). They were sacrificed 1, 3, 6, and 9 months after implantation (n = 5 individuals per group/period). Histomorphometric analysis included i) counting of polymorphonuclear leucocytes, mast cells, macrophages and foreign body multinucleated giant cells stained with anti-lysozyme; ii) microvascular density stained with anti-Factor VIII and iii) degree of cell proliferation stained with anti-PCNA. There were no significant differences between the experimental groups in either the quality or quantity of cells in the inflammatory infiltrate, or the degree of angiogenesis and cell proliferation. We conclude that HA-1 and HA-2 are biocompatible and that the physico-chemical differences of these biomaterials did not affect cellular response. AD - COPPE and Polytechnic School, Federal University of Rio de Janeiro - UFRJ, P.O. Box 68505, 21941-972 Rio de Janeiro, RJ, Brazil Department of Cell and Molecular Biology, Antonio Pedro University Hospital - HUAP, Fluminense Federal University - UFF, 24020-150 Niterói, RJ, Brazil Department of Pathology, Antonio Pedro University Hospital - HUAP, Fluminense Federal University - UFF, 24033-900 Niterói, RJ, Brazil AU - de Freitas Costa, N. AU - Melo, B. R. AU - Brito, R. T. AU - de Oliveira Fernandes, M. B. AU - Bernardo, V. G. AU - Fonseca, E. C. AU - Conz, M. B. AU - Soares, G. A. AU - Granjeiro, J. M. DB - Scopus DO - 10.1590/s1516-14392009000200022 IS - 2 KW - Bone repair Histomorphometry Hydroxyapatite Immunohistochemistry M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2009 SP - 245-251 ST - Quality and intensity of the tissue response to two synthetic granular hydroxyapatite implanted in critical defects of rat calvaria T2 - Materials Research TI - Quality and intensity of the tissue response to two synthetic granular hydroxyapatite implanted in critical defects of rat calvaria UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-68649111667&doi=10.1590%2fs1516-14392009000200022&partnerID=40&md5=b6133129f9c9b0d8d5524318ee5b933f VL - 12 ID - 1506 ER - TY - JOUR AB - OBJECTIVE: To describe incidents of retained surgical items, including their characteristics and the circumstances in which they occur. DESIGN: A qualitative content analysis of root cause analysis investigation reports. SETTING: Public health services in Victoria, Australia, 2010-2015. PARTICIPANTS: Incidents of retained surgical items as described by 31 root cause analysis investigation reports. MAIN OUTCOME MEASURE(S): The type of retained surgical item, the length of time between the item being retained and detected and qualitative descriptors of the contributing factors and the circumstances in which the retained surgical items occurred. RESULTS: Surgical packs, drain tubes and vascular devices comprised 68% (21/31) of the retained surgical items. Nearly one-quarter of the retained surgical items were detected either immediately in the post-operative period or on the day of the procedure (7/31). However, about one-sixth (5/31) were only detected after 6 months, with the longest period being 18 months. Contributing factors included complex or multistage surgery; the use of packs not specific to the purpose of the surgery; and design features of the surgical items. CONCLUSION: Retained drains occurred in the post-operative phase where surgical counts are not applicable and clinician situational awareness may not be as great. Root cause analysis investigation reports can be a valuable means of characterizing infrequently occurring adverse events such as retained surgical items. They may detect incidents that are not detected by other data collections and can inform the design enhancements and development of technologies to reduce the impact of retained surgical items. AD - Australian Institute of Health Innovation, Macquarie University, New South Wales, Australia. Australian Centre for Precision Health, Cancer Research Institute, School of Health Sciences, University of South Australia, Adelaide, South Australia, Australia. South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia. Appleton Institute, CQ University, Adelaide, South Australia, Australia. Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, Wales, United Kingdom. AN - 32227116 AU - Hibbert, P. D. AU - Thomas, M. J. W. AU - Deakin, A. AU - Runciman, W. B. AU - Carson-Stevens, A. AU - Braithwaite, J. DA - May 20 DO - 10.1093/intqhc/mzaa005 DP - NLM ET - 2020/04/01 IS - 3 KW - Enablers Healthcare teams Psychological safety LA - eng N1 - 1464-3677 Hibbert, Peter D Thomas, Matthew J W Deakin, Anita Runciman, William B Carson-Stevens, Andrew Braithwaite, Jeffrey Journal Article England Int J Qual Health Care. 2020 May 20;32(3):184-189. doi: 10.1093/intqhc/mzaa005. PY - 2020 SN - 1353-4505 SP - 184-189 ST - A qualitative content analysis of retained surgical items: learning from root cause analysis investigations T2 - Int J Qual Health Care TI - A qualitative content analysis of retained surgical items: learning from root cause analysis investigations VL - 32 ID - 245 ER - TY - JOUR AB - Liver abscess due to perforation of the gastrointestinal tract by a foreign body is a rare and possibly fatal event. Diagnosing this pathology is complicated by the lack of specific symptoms and unfamiliarity of ingestion by the patient and low clinical suspicion of this disease. In the case of liver abscess unresponsive to aspiration and administration of antibiotics, this hypothesis must be made, despite its low incidence. This case report describes and illustrates a case of liver abscess secondary to fish bone ingestion with consequent piercing of the lesser gastric curvature, diagnosed by computed tomography and specific anamnesis. Laparoscopy was performed to extract the foreign body, without complications; the patient is currently asymptomatic and does not present any abnormal physical examination findings. We believe this represents the first case report of a successful laparoscopic treatment in South America for the removal of an ingested foreign body associated with pyogenic liver abscess. © 2018, Fundacion Clinica Medica Sur. All rights reserved. AD - Division of Internal Medicine, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil Department of Internal Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil Division of General Surgery, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil Department of Surgery, Postgraduate Course of Surgery, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil Liver and Pancreas Transplant and Hepatobiliary Surgery Unit, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil AU - Bandeira-De-Mello, R. G. AU - Bondar, G. AU - Schneider, E. AU - Wiener-Stensmann, I. C. AU - Gressler, J. B. AU - Kruel, C. R. P. DB - Scopus DO - 10.5604/01.3001.0010.7550 IS - 1 KW - CT Foreign body penetration Hepatic abscess Perforation Videolaparoscopy M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2018 SP - 169-173 ST - Pyogenic liver abscess secondary to foreign body (Fish bone) treated by laparoscopy: A case report T2 - Annals of Hepatology TI - Pyogenic liver abscess secondary to foreign body (Fish bone) treated by laparoscopy: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85039839582&doi=10.5604%2f01.3001.0010.7550&partnerID=40&md5=51e1be5aa0fd6d62dd0dea3821cdeadd VL - 17 ID - 1096 ER - TY - JOUR AB - Pulse granuloma is a rare pathologic condition considered to be a benign inflammatory reaction to foreign materials originated from ingested legume matter. As for pulse granulomas of the gastrointestinal tract, association with diverticular diseases is relatively common, but only a few pulse granuloma cases associated with appendicitis have been reported. This report presents histopathologic findings of pulse granuloma lesions observed in two appendectomy cases, with some histochemical examinations of cellulose matter which is reportedly a major component to provoke pulse granuloma reaction. Our patients in both cases were girls in their teens, and they underwent interval appendectomy for acute appendicitis. Both appendectomy specimens revealed ruptured walls with inflammatory granulation tissue with marked foreign body reaction including characteristic collections of ring-like, curled ribbon-like, and/or lobulated nephrosclerosis-like hyaline structures and various foreign bodies, in which microorganisms or amyloid deposition were not identified. The presence of cellulose matter was suggested by Sirius red stain, the IKI (iodine potassium iodide)-H 2 SO 4 method, and birefringence by polarized light. Appendectomy materials due to acute appendicitis would include pulse granuloma reaction provoked by ingested materials with cellulose. Pathologists should be familiar with the concept and histopathologic features of pulse granulomas to avoid misinterpreting them as vascular lesions and/or amyloid deposition, or any infectious organisms. © 2018 The Author(s). Published by S. Karger AG, Basel. AD - Department of Pathology, Dokkyo Medical University Saitama Medical Center, 2-1-50 Minami-Koshigaya, Koshigaya, Saitama, 343-8555, Japan Department of Pathology, Kasukabe Medical Center, Kasukabe, Japan Department of Pediatric Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan Department of Surgery, Kasukabe Medical Center, Kasukabe, Japan AU - Ban, S. AU - Fujii, A. AU - Takimoto, T. AU - Kikuchi, K. AU - Kang, W. AU - Namiki, Y. AU - Koyatsu, J. AU - Ueda, Y. DB - Scopus DO - 10.1159/000495318 IS - 3 KW - Appendicitis Appendix Cellulose Interval appendectomy Pulse granuloma M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2018 SP - 765-772 ST - Pulse Granulomas in Interval Appendectomy Specimens: Histochemical Identification of Cellulose Matter T2 - Case Reports in Gastroenterology TI - Pulse Granulomas in Interval Appendectomy Specimens: Histochemical Identification of Cellulose Matter UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85059114224&doi=10.1159%2f000495318&partnerID=40&md5=0a934c4002c2cd12d7152186523c2a51 VL - 12 ID - 1061 ER - TY - JOUR AB - Background: Pulmonary artery embolization due to projectile embolus is a rare complication in combat patients. Such embolization is rare for combat patients in the ongoing armed conflict, in East Ukraine since 2014. Case presentation: We report a clinical case of a 34-year-old Caucasian combat patient who was injured after an explosion of a booby trap hand grenade. This soldier was diagnosed with severe abdominal and skeletal trauma: damage of the duodenum and transverse colon, internal bleeding due to inferior vena cava damage and fractures of both lower extremities. The patient was treated at a highly specialized surgical center within the "golden hour" time. Whole-body computed tomography scan was performed as a routine screening method for hemodynamically stable patients, at which we identified a projectile embolus due to the explosion of a booby trap hand grenade in the right midlobar pulmonary artery. Our patient had no clinical manifestation of pulmonary artery embolism. At follow-up, our patient was diagnosed with the following complications: multiple necrosis and perforations of the transverse colon leading to a fecal peritonitis; duodenum suture line leakage caused the formation of a duodenal fistula; postoperative wound infection. These complications required multiple secondary operations, and in accordance to the principles of damage-control tactics, the extraction of projectile-embolus was postponed. Open surgery retrieval of the metal fragment was successfully performed on the 80th day after injury. Our patient was discharged from the hospital on day 168th after injury. Conclusions: Literature analysis shows a significant difference of clinical management for patient with projectile embolism in hybrid war settings as compared to previously described cases of combat and civil gunshot injuries. Damage control tactics and the concept of the "golden hour" are highly effective for those injured in a hybrid war. A whole-body computed tomography scan is an effective screening method for asymptomatic patients with projectile-embolism of the great vessels. The investigation of a greater cohort of combat patients with severe injuries and projectile-embolism should be performed in order to develop a better guideline for these patients and to save more lives. © 2018 The Author(s). AD - Department of Abdominal Surgery, National Military Medical Clinical Center, Ministry of Defense of Ukraine, Kiev, Ukraine Department of Surgery 4, Olexandrivska Teaching Hospital, Bogomolets National Medical University, Shovkovychna 39/1 str, Kiev, Ukraine Department of Thoracic Surgery, National Military Medical Clinical Center, Ministry of Defense of Ukraine, Kiev, Ukraine Department of Thoraco-Abdominal Surgery, Military Medical Clinical Center of the Northern Region, Ministry of Defense of Ukraine, Kharkiv, Ukraine Department of Abdominal Surgery, Military Medical Clinical Center, Sothern Region of Ministry of Defense of Ukraine, Odessa, Ukraine AU - Khomenko, I. AU - Tsema, I. AU - Shklyarevych, P. AU - Kravchenko, K. AU - Holinko, V. AU - Nikolaienko, S. AU - Shypilov, S. AU - Gerasimenko, O. AU - Dinets, A. AU - Mishalov, V. C7 - 330 DB - Scopus DO - 10.1186/s13256-018-1834-5 IS - 1 KW - Armed conflict in Ukraine Combat trauma Damage control Hybrid warfare Projectile-embolus M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 ST - Pulmonary artery embolism by a metal fragment after a booby trap explosion in a combat patient injured in the armed conflict in East Ukraine: A case report and review of the literature 11 Medical and Health Sciences 1103 Clinical Sciences T2 - Journal of Medical Case Reports TI - Pulmonary artery embolism by a metal fragment after a booby trap explosion in a combat patient injured in the armed conflict in East Ukraine: A case report and review of the literature 11 Medical and Health Sciences 1103 Clinical Sciences UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85056144014&doi=10.1186%2fs13256-018-1834-5&partnerID=40&md5=b4f12b6995883769268d3a1724c91f48 VL - 12 ID - 1056 ER - TY - JOUR AD - Associate director for the Centers for Health and Aging, Director of nursing research for health and aging, Dartmouth-Hitchcock Medical Center, Lebanon, NH. AN - 105588199. Language: English. Entry Date: 20090130. Revision Date: 20150818. Publication Type: Journal Article. Journal Subset: Core Nursing AU - Beyea, S. C. DB - ccm DO - 10.1016/j.aorn.2008.11.024 DP - EBSCOhost IS - 6 KW - Patient Safety Perioperative Care Checklists Information Resources Outcomes (Health Care) Surgical Count Procedure World Health Organization N1 - Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PMID: NLM19054490. PY - 2008 SN - 0001-2092 SP - 1009-1011 ST - Published resources for improving patient care T2 - AORN Journal TI - Published resources for improving patient care UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105588199&site=ehost-live&scope=site VL - 88 ID - 815 ER - TY - JOUR DB - Scopus DO - 10.1016/S0001-2092(06)63893-3 IS - 2 M3 - Article N1 - Export Date: 10 November 2020 PY - 1995 SP - 404, 406, 408-411 ST - Proposed recommended practices for sponge, sharp, and instrument counts. Association of Operating Room Nurses T2 - AORN journal TI - Proposed recommended practices for sponge, sharp, and instrument counts. Association of Operating Room Nurses UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029248865&doi=10.1016%2fS0001-2092%2806%2963893-3&partnerID=40&md5=a532e9d5bddf33dc025a5bf2bd21dc99 VL - 61 ID - 1722 ER - TY - JOUR AB - Introduction: Identification of the ureterduring colectomies is essential to preventiatrogenic injuries to the ureter fromoccurring. The usage of ureteric stents toaid identification has been and still is ahotly debated topic. The prophylacticinsertion of ureteral stents may facilitateidentification of the ureter and allows earlyrecognition of ureteric injuries in colectomies.Materials and Methods: All patients whounderwent colonic resection in UniversitiKebangsaan Malaysia Medical Centerbetween January 2015 and August 2018were analyzed. Demographic data, operative details and post-operative laboratorydata were collected. The primary outcomesof ureteral injury were compared betweenpatients who underwent colonic resectionwith prophylactic insertion of ureteralstent and patients who underwent colonicresection without prophylactic insertionureteral stents. Secondary outcomes ofduration of operation, perioperative whitecell count and perioperative serum creatinine were also compared. Statistical analyses were performed by the Student's ttest as appropriate and statistical significance was indicated by P < 0.05.Results: Between January 2015 andAugust 2018, a total of 526 colectomieswere performed with a larger number ofpatients not submitted to prophylacticureteral stent insertion (490 [93.2%] vs 36[6.8%]). The amount of emergency andelective operations were similar (271[51.5%] vs 255 [48.5]) with more openprocedures were performed as opposed tolaparoscopic resection (357 [67.8%] vs 169[32.1%]). Two ureteral injuries occurredand both these cases did not have prophylactic insertion of ureteral stents (0.4%). We found that there was no significantdifference in mean perioperative serumcreatinine (81.8 [7.5] vs 86.6 [2.3];P = 0.5921). There was a significance indifference in perioperative white cell count(12.54 [0.2] vs 15.39 [1.3]; P = <0.05) andoperating time (in minutes; 329.9 [22.4] vs213 [4.5]; P = <0.05) which may be due toa reaction to foreign body insertion andextra time needed to place stents respectively.Conclusion: In this cohort of 526 patientsundergoing bowel resection, prophylacticureteral stent insertion was associated withincreased operating duration and whitecell count. The rate of ureteral injury wassignificantly low and it occurred in apatient without ureteral stents. Ureteralinjury is a serious complication in colorectal surgery and utility of prophylactic ureteral stents are still controversial. AD - Z.A. Zainal Adwin, Department of Surgery Surgical Sciences Cluster, Faculty of Medicine, Universiti Teknologi MARA, Selangor, Malaysia AU - Zainal Adwin, Z. A. AU - Shukor, S. AU - Jasman, H. AU - Zainuddin, Z. DB - Embase DO - 10.1111/bju.14547 KW - adult case report clinical article colon resection colorectal surgery complication conference abstract creatinine blood level demography emergency female foreign body human human tissue leukocyte count Malaysia male outcome assessment statistical analysis statistical significance student surgery ureter injury ureter stent LA - English M3 - Conference Abstract N1 - L625235545 2018-12-04 PY - 2018 SN - 1464-410X SP - 13-14 ST - Prophylactic ureteral stents incolectomies: Is it really required? T2 - BJU International TI - Prophylactic ureteral stents incolectomies: Is it really required? UR - https://www.embase.com/search/results?subaction=viewrecord&id=L625235545&from=export http://dx.doi.org/10.1111/bju.14547 VL - 122 ID - 332 ER - TY - JOUR AB - The article discusses a process designed by nurses to prevent the unintended retention of a foreign object (RFO) in a patient undergoing a vaginal delivery. It discusses the process of recognizing the need to develop a policy to promote patient safety in women's health, and to provide an accurate vaginal sponge count. Also examined is the potential of a process change for nurses and physicians including counting in a vaginal delivery to prevent RFO. AD - BSN, RNC-OB, Labor and Delivery, Baylor University Medical Center, Dallas, TX BSN, RNC-OB, EFM-C, Labor and Delivery, Baylor University Medical Center, Dallas, TX AN - 60975568. Language: English. Entry Date: 20110715. Revision Date: 20120501. Publication Type: Article AU - Rich, Diana AU - Bural, Kelli DB - ccm DO - 10.1111/j.1552-6909.2011.01242_98.x DP - EBSCOhost KW - Vaginal Birth Adverse Health Care Event -- Prevention and Control Intrapartum Care Surgical Count Procedure Retained Instruments Posters Female Adult Pregnancy Hospital Policies N1 - abstract. Supplement Title: May2011 Supplement 1. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Special Interest: Patient Safety. NLM UID: 8503123. PY - 2011 SN - 0884-2175 SP - S70-S71 ST - Promoting Women's Health One Sponge at a Time T2 - JOGNN: Journal of Obstetric, Gynecologic & Neonatal Nursing TI - Promoting Women's Health One Sponge at a Time UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=60975568&site=ehost-live&scope=site VL - 40 ID - 896 ER - TY - JOUR AB - Fish bones are one of the most frequently observed ingested foreign bodies in the pharynx-esophagus. Fish bones have a tendency to stick and penetrate the mucosa, which can occasionally lead to severe or lethal complications. The extraluminal migration of fish bones in the upper digestive tract is a rare event, and it is even more unlikely that the foreign body will remain in the neck for a prolonged period. We report the unique case of a 69-year-old woman who remained asymptomatic, while a fish bone was lodged in her neck for 9 months. Finally, after her anterior neck had become swollen, she underwent neck exploration, which revealed that the fish bone was embedded in the scar tissue running from within the thyroid gland to outside of the thyroid. Treatment proceeded without complications, and the foreign body was removed successfully. The length of the fish bone was 34 mm. Intraoperative ultrasonography was able to identify the fish bone in situ using real-time imaging; therefore, we recommend this technique for locating migrated foreign bodies in the neck. © 2012 Tohoku University Medical Press. AD - Department of Otolaryngology, National Sendai Medical Center, Sendai, Japan Department of Otolaryngology, Sendai Social Insurance Hospital, Sendai, Japan AU - Watanabe, K. AU - Amano, M. AU - Nakanome, A. AU - Saito, D. AU - Hashimoto, S. DB - Scopus DO - 10.1620/tjem.227.49 IS - 1 KW - Complication Fish bone Migration Prolonged presence Ultrasonography M3 - Article N1 - Cited By :16 Export Date: 10 November 2020 PY - 2012 SP - 49-52 ST - The prolonged presence of a fish bone in the neck T2 - Tohoku Journal of Experimental Medicine TI - The prolonged presence of a fish bone in the neck UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84865298925&doi=10.1620%2ftjem.227.49&partnerID=40&md5=8c07292762ee1ce65ffe7af6edda2a9d VL - 227 ID - 1360 ER - TY - JOUR AB - Most migrated foreign bodies in the neck were removed immediately in patients with persistent symptoms. It is a rare condition that a fish bone was buried for a prolonged time in the tongue with little discomfort. We report a unique case of an ingested fish bone lodged in the tongue for 16 months until infection ensued. Ludwig angina was considered first because the patient had fever, odynophagia, swelling of the tongue, and mouth floor. The fish bone buried in the tongue was incidentally found on the computed tomography scan and successfully removed by surgical exploration. Although dental infection is the most common underlying cause in Ludwig angina, embedded foreign body should be considered as one of the pathogenesis. On the other hand, computed tomography scan can be useful in identifying extraluminal migration of fish bones in the neck. © 2011 Elsevier Inc. AD - Department of Otolaryngology, En Chu Kong Hospital, 399 Fushing Rd., San-shia Town, Taipei Hsien 237, Taiwan AU - Hsu, C. L. AU - Chen, C. W. DB - Scopus DO - 10.1016/j.amjoto.2009.09.003 IS - 1 M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2011 SP - 75-76 ST - A prolonged buried fish bone mimicking Ludwig angina T2 - American Journal of Otolaryngology - Head and Neck Medicine and Surgery TI - A prolonged buried fish bone mimicking Ludwig angina UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-78649752542&doi=10.1016%2fj.amjoto.2009.09.003&partnerID=40&md5=fd0e390f10fc823cde0c06aa1108b41a VL - 32 ID - 1435 ER - TY - JOUR DB - Scopus IS - 3 M3 - Article N1 - Export Date: 10 November 2020 PY - 2003 SP - 11-12 ST - Projects for improving safety of counts in the OR T2 - OR manager TI - Projects for improving safety of counts in the OR UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037361099&partnerID=40&md5=a68efc9b12ed250d7a1c20a3cd97509b VL - 19 ID - 1647 ER - TY - JOUR AB - The purpose of this study is to evaluate the prognostic factors associated with visual outcomes in the salvageable eyes with posttraumatic endophthalmitis. We retrospectively reviewed the medical records of all patients diagnosed with posttraumatic endophthalmitis in our hospital between 2008 and 2015. The following information was collected: age, sex, etiology, past medical history, clinical manifestations, wound location, microbiology, blood leukocyte counts, types of interventions, initial visual acuities and final visual acuities. Univariate and multivariate analyses were used to explore the factors associated with final best-corrected visual acuity. In total, 98 eyes of 98 patients were included in our study. Fifty-seven eyes underwent vitrectomy, 27 of them had silicone oil tamponade, 38 eyes received intravitreal ceftazidime only and 3 eyes received intracameral ceftazidime. In univariate analysis, poor initial visual acuity, presence of intraocular foreign body, number of intravitreal injections, retinal detachment and Zone 3 injury were associated with poor visual outcome. In multivariable analysis, poor initial visual acuity, presence of intraocular foreign body and number of intravitreal injections were independently associated with poor visual outcome. The silicone oil group had fewer repeated intravitreal injections than the group without oil tamponade. We concluded that the visual outcome of salvageable eyes with posttraumatic endophthalmitis is associated with initial visual acuity, presence of intraocular foreign body and number of intravitreal antibiotic injections. AU - Lu, X. AU - Xia, H. AU - Jin, C. AU - Chen, W. AU - Siu-Chun Ng, D. AU - Yan, H. AU - Chen, H. DB - Medline DO - 10.1038/s41598-019-49117-w IS - 1 KW - antiinfective agent ceftazidime silicone oil adolescent adult aged child drug effect endophthalmitis female human isolation and purification male microbiology middle aged pathology preschool child prognosis retina detachment retrospective study Staphylococcus epidermidis visual acuity vitrectomy young adult LA - English M3 - Article N1 - L629218148 2019-09-10 2020-11-09 PY - 2019 SN - 2045-2322 SP - 12678 ST - Prognostic factors associated with visual outcome of salvageable eyes with posttraumatic endophthalmitis T2 - Scientific reports TI - Prognostic factors associated with visual outcome of salvageable eyes with posttraumatic endophthalmitis UR - https://www.embase.com/search/results?subaction=viewrecord&id=L629218148&from=export http://dx.doi.org/10.1038/s41598-019-49117-w VL - 9 ID - 307 ER - TY - JOUR AB - Aseptic loosening is the predominant cause of total hip implant failure. It has been assumed that a layer or membrane, containing macrophages, fibroblasts and vascular endothelial cells, of synovial-like tissue develops at the implant-to-bone interface almost invariably and, with time, somehow leads to loosening of the components from the surrounding bone. These cells produce a variety of cytokines and proteolytic enzymes which stimulate bone resorption. Platelet derived growth factor (PDGF) may be one of the cytokines which stimulate bone resorption and contribute to aseptic loosening in total hip replacement (THR). Synovial-like membrane from the implant or cement-to-bone interface (n = 10) and pseudocapsule (n = 10) were obtained from ten patients operated on for aseptic loosening of THR. As a control, nine samples of connective tissues were obtained from patients who had mandibular or maxillary fractures fixed with bone implant. The avidin-biotin-peroxidase complex (ABC) method with polyclonal rabbit anti-human IgG against the A-chain and B-chain of PDGF was used for staining. ABC-alkaline phosphatase-anti-alkaline-phosphatase double staining with monoclonal mouse anti-human fibroblast IgG, and CD68 antibodies was used to ascertain the cellular origin of PDGF. Results of the PDGF staining were quantitated by a semi-automatic VIDAS image analysis system. The PDGF-A and PDGF-B chain containing cells were found in all periprosthetic tissues, in particular in macrophages with phagocytosed particulate debris, but to some extent also in fibroblasts and in endothelial cells. The numbers of PDGF-A and PDGF-B chain positive cells per mm2 in synovial-like interface membrane (1881 ± 486 and 1877 ± 214) and pseudocapsule (1786 ± 236 and 1676 ± 152) were higher (P < 0.01) around loose THR than in control tissue (821 ± 112 and 467 ± 150), respectively. The results of the present study suggest that PDGF is preferably expressed by macrophages, which to an increased extent produce it in the synovial-like interface membrane and pseudocapsular synovial-like membrane. Because of its role in bone resorption, it may well play a role in periprosthetic bone loss and aseptic loosening and deserves more detailed study as a mediator and potential target in the modulation or prevention of loosening of THR. AD - Molecular Biology Laboratory, Musculoskel. Dis. Inflammation R., University of Helsiniki, P.O. Box 9 (Siltavuorenpenger 20 A), FIN-00014, Finland Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland Dept. Orthopaedics and Traumatology, Helsinki University Central Hospital, Helsinki, Finland Istituto di Clinica Medica IV, University of Florence, Firenze, Italy AU - Xu, J. W. AU - Konttinen, Y. T. AU - Li, T. F. AU - Waris, V. AU - Lassus, J. AU - Matucci-Cerinic, M. AU - Sorsa, T. AU - Santavirta, S. DB - Scopus DO - 10.1007/s002960050037 IS - 6 KW - Aseptic loosening Platelet-derived growth factor Synovial-like membrane Total hip replacement M3 - Article N1 - Cited By :26 Export Date: 10 November 2020 PY - 1998 SP - 215-221 ST - Production of platelet-derived growth factor in aseptic loosening of total hip replacement T2 - Rheumatology International TI - Production of platelet-derived growth factor in aseptic loosening of total hip replacement UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031945140&doi=10.1007%2fs002960050037&partnerID=40&md5=ded136007fc8ef4190cc9b428903ab2b VL - 17 ID - 1696 ER - TY - JOUR AN - 105787507. Language: English. Entry Date: 20080815. Revision Date: 20200623. Publication Type: Journal Article AU - Burger, V. DB - ccm DO - 10.1188/08.onf.722-723 DP - EBSCOhost IS - 4 KW - Oncologic Care -- Equipment and Supplies Bandages and Dressings Breast Neoplasms -- Prevention and Control Catheters, Urinary Ostomy Equipment and Supplies Surgical Count Procedure N1 - pictorial. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 7809033. PY - 2008 SN - 0190-535X SP - 722-723 ST - Product update. New products T2 - Oncology Nursing Forum TI - Product update. New products UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105787507&site=ehost-live&scope=site VL - 35 ID - 851 ER - TY - JOUR AB - BACKGROUND: Perforating injuries continue to have a poor prognosis with less than two-thirds of eyes having at least ambulatory final vision, due to proliferation originating from the exit wound. MATERIALS AND METHODS: We developed a new, proactive treatment method, which is applicable in most eyes with perforating trauma. The strategy involves limited, indirect ophthalmoscopic vitrectomy during the primary repair; heavy topical corticosteroid therapy postoperatively; and complete vitrectomy on day 3, including prophylactic retinectomy around the exit wound, evacuation of subretinal blood, laser retinopexy, and silicone oil implantation. RESULTS: In the five consecutive eyes in which the proactive treatment approach was used, no "enscarceration" of the retina into the exit wound, proliferative vitreoretinopathy, retinal detachment, or retinal folding has occurred. The median visual acuity improved from count fingers to 0.6 in the three eyes without macular involvement. CONCLUSIONS: Far-reaching conclusions must not be made based on such a small series, but the proactive treatment approach appears promising in preventing proliferation-related complications such as tractional retinal detachment or retinal fold development. A similar approach should be considered for eyes with deep impact trauma from intraocular foreign bodies and in eyes with retinal incarcerated retina in the rupture wound. AD - University of Alabama at Birmingham, Birmingham, AL 35205, USA. fkuhn@mindspring.com AN - 15343445 AU - Kuhn, F. AU - Mester, V. AU - Morris, R. DA - Aug DO - 10.1055/s-2004-813535 DP - NLM ET - 2004/09/03 IS - 8 KW - Combined Modality Therapy/methods *Decision Support Systems, Clinical Emergency Medical Services/*methods Eye Injuries, Penetrating/surgery/*therapy Humans Ophthalmologic Surgical Procedures/*methods Patient Care Management/*methods Perioperative Care/methods Practice Guidelines as Topic Preoperative Care/methods Reconstructive Surgical Procedures/*methods Treatment Outcome LA - eng N1 - Kuhn, F Mester, V Morris, R Journal Article Germany Klin Monbl Augenheilkd. 2004 Aug;221(8):622-8. doi: 10.1055/s-2004-813535. PY - 2004 SN - 0023-2165 (Print) 0023-2165 SP - 622-8 ST - A proactive treatment approach for eyes with perforating injury T2 - Klin Monbl Augenheilkd TI - A proactive treatment approach for eyes with perforating injury VL - 221 ID - 50 ER - TY - JOUR AD - First Department of Surgery, 424 General Military Hospital, Periferiakos Eukarpies, Thessaloniki, 56429, Greece Department of Pathology, 424 General Military Hospital, Thessaloniki, Greece Department of Microbiology, 424 General Military Hospital, Thessaloniki, Greece Department of Gastroenterology, 424 General Military Hospital, Thessaloniki, Greece Department of Infectious Diseases, 424 General Military Hospital, Thessaloniki, Greece Department of Intensive Care Unit, 424 General Military Hospital, Thessaloniki, Greece AU - Chatzoulis, G. AU - Pappas, D. AU - Karagiozopoulos, T. AU - Moschos, J. AU - Karapiperis, D. AU - Barpagiannis, A. AU - Pantelidou, V. AU - Makrakis, V. AU - Pachiadakis, I. DB - Scopus DO - 10.1089/sur.2013.140 IS - 5 M3 - Article N1 - Export Date: 10 November 2020 PY - 2014 SP - 667-669 ST - Primary omental abscess with increased concentrations of carcinoembryonic antigen T2 - Surgical Infections TI - Primary omental abscess with increased concentrations of carcinoembryonic antigen UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84911996532&doi=10.1089%2fsur.2013.140&partnerID=40&md5=4cbfd1084edab6b11da520430ba71be1 VL - 15 ID - 1269 ER - TY - JOUR AB - Background: Postoperative retrosternal adhesion increases the risk of cardiac injury during cardiac reoperation. We created a novel biodegradable glue called "Lydex" that is derived from food additives. The purpose of this study is to evaluate this new biomaterial's biocompatibility and its preventive effect on retrosternal adhesion. Methods: We performed a median sternotomy and anterior pericardiectomy on Japanese white rabbits, and then closed the chest (control, group 1; n = 12), implanted an expanded polytetrafluoroethylene membrane (group 2; n = 12), or applied Lydex (group 3; n = 12) before closure. After 4 weeks, we evaluated macroscopic adhesion (each group; n = 6) and microscopic findings for fibrosis and macrophage infiltration (each group; n = 6). Results: In group 3, the retrosternal adhesion score was significantly lower than in group 1 (P =.0022). There was no significant difference between groups 2 and 3. The fibrotic area ratio was significantly lower in group 3 than in groups 1 and 2 (P <.001 vs group 1; P <.001 vs group 2). In group 3, the macrophage count was significantly lower than in group 2 (P <.001) and almost equal to that in group 1. Conclusions: Our findings indicate that Lydex reduces retrosternal adhesion and attenuates the progression of fibrosis with excellent biocompatibility. Lydex is a next-generation substance for safer cardiac reoperation, with excellent capability for preventing adhesion, biocompatible and biodegradable properties, and lower potential for viral infections related to human plasma or other animal-derived products. Copyright © 2013 by The American Association for Thoracic Surgery. AD - Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 603-8507, Japan Department of Forensic Medicine and Molecular Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan Center for Fiber and Textile Science, Kyoto Institute of Technology, Kyoto, Japan AU - Kamitani, T. AU - Masumoto, H. AU - Kotani, H. AU - Ikeda, T. AU - Hyon, S. H. AU - Sakata, R. DB - Scopus DO - 10.1016/j.jtcvs.2013.02.001 IS - 5 M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2013 SP - 1232-1238 ST - Prevention of retrosternal adhesion by novel biocompatible glue derived from food additives T2 - Journal of Thoracic and Cardiovascular Surgery TI - Prevention of retrosternal adhesion by novel biocompatible glue derived from food additives UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84885921735&doi=10.1016%2fj.jtcvs.2013.02.001&partnerID=40&md5=3923e9ae32b176bb3ba92f6ab4831265 VL - 146 ID - 1305 ER - TY - JOUR AB - BACKGROUND: New technologies are available to reduce or prevent retained surgical sponges (RSS), but their relative cost effectiveness are unknown. We developed an empirically calibrated decision-analytic model comparing standard counting against alternative strategies: universal or selective x-ray, bar-coded sponges (BCS), and radiofrequency-tagged (RF) sponges. METHODS: Key model parameters were obtained from field observations during a randomized-controlled BCS trial (n = 298), an observational study of RSS (n = 191,168), and clinical experience with BCS (n approximately 60,000). Because no comparable data exist for RF, we modeled its performance under 2 alternative assumptions. Only incremental sponge-tracking costs, excluding those common to all strategies, were considered. Main outcomes were RSS incidence and cost-effectiveness ratios for each strategy, from the institutional decision maker's perspective. RESULTS: Standard counting detects 82% of RSS. Bar coding prevents > or =97.5% for an additional $95,000 per RSS averted. If RF were as effective as bar coding, it would cost $720,000 per additional RSS averted (versus standard counting). Universal and selective x-rays for high-risk operations are more costly, but less effective than BCS-$1.1 to 1.4 million per RSS event prevented. In sensitivity analyses, results were robust over the plausible range of effectiveness assumptions, but sensitive to cost. CONCLUSION: Using currently available data, this analysis provides a useful model for comparing the relative cost effectiveness of existing sponge-tracking strategies. Selecting the best method for an institution depends on its priorities: ease of use, cost reduction, or ensuring RSS are truly "never events." Given medical and liability costs of >$200,000 per incident, novel technologies can substantially reduce the incidence of RSS at an acceptable cost. AD - Department of Health Policy and Management, Harvard School of Public Health, Boston, MA, USA. sregenbogen@partners.org AN - 19375612 AU - Regenbogen, S. E. AU - Greenberg, C. C. AU - Resch, S. C. AU - Kollengode, A. AU - Cima, R. R. AU - Zinner, M. J. AU - Gawande, A. A. C2 - PMC2725304 C6 - NIHMS114760 DA - May DO - 10.1016/j.surg.2009.01.011 DP - NLM ET - 2009/04/21 IS - 5 KW - Contrast Media Cost-Benefit Analysis *Decision Support Techniques Foreign Bodies/*economics/epidemiology/*prevention & control Humans Incidence *Intraoperative Complications Isotope Labeling Models, Economic Predictive Value of Tests Sensitivity and Specificity Surgical Sponges/*adverse effects/*economics LA - eng N1 - 1532-7361 Regenbogen, Scott E Greenberg, Caprice C Resch, Stephen C Kollengode, Anantha Cima, Robert R Zinner, Michael J Gawande, Atul A L30 DK075553-01/DK/NIDDK NIH HHS/United States T32 HS000020/HS/AHRQ HHS/United States Journal Article Research Support, Non-U.S. Gov't Surgery. 2009 May;145(5):527-35. doi: 10.1016/j.surg.2009.01.011. Epub 2009 Mar 21. PY - 2009 SN - 0039-6060 (Print) 0039-6060 SP - 527-35 ST - Prevention of retained surgical sponges: a decision-analytic model predicting relative cost-effectiveness T2 - Surgery TI - Prevention of retained surgical sponges: a decision-analytic model predicting relative cost-effectiveness VL - 145 ID - 90 ER - TY - JOUR AB - Reduction in retained surgical items is an important part of any operating room patient-safety effort. Any item used in an operation can result in a retained surgical item, but sponges are the most frequent and the abdomen is the most common location. Retained sponges can cause significant morbidity, and the costs associated with both prevention and treatment of retained surgical items, including legal costs, can be considerable. This review will examine counting, teamwork, radiography, and new technology as methods used to prevent retained surgical items. Even though none of these techniques individually is likely to completely prevent retained surgical items, when used together the numbers can be reduced. AD - Hospitals Insurance Company, Inc., New York, NY, USA. dfeldman@fojp.com AN - 22069210 AU - Feldman, D. L. DA - Nov-Dec DO - 10.1002/msj.20299 DP - NLM ET - 2011/11/10 IS - 6 KW - Electronic Data Processing Foreign Bodies/diagnostic imaging/*prevention & control Humans Medical Errors/*prevention & control Postoperative Complications/*prevention & control Radio Frequency Identification Device Radiography Safety Management Surgical Sponges/*adverse effects LA - eng N1 - 1931-7581 Feldman, David L Journal Article Review United States Mt Sinai J Med. 2011 Nov-Dec;78(6):865-71. doi: 10.1002/msj.20299. PY - 2011 SN - 0027-2507 SP - 865-71 ST - Prevention of retained surgical items T2 - Mt Sinai J Med TI - Prevention of retained surgical items VL - 78 ID - 116 ER - TY - JOUR AB - Purpose: Spinal epidural fibrosis and adhesion are implicated as one of the key factors of failed back surgery syndrome, which may cause dura mater compression or peridural tethering, resulting in persistent backache and leg pain. Various materials or drugs have been used to inhibit formation of epidural fibrosis and reduce the compressive effect on neural structures. Nevertheless, the effects are not satisfied. In this study, we investigated the prevention effect of poly (l-glutamic acid)/chitosan (PLGA/CS) barrier on epidural fibrosis developing post-laminectomy in a rabbit model. Methods: Sixteen rabbits were divided randomly into two equal groups: group A (experimental group, n = 8) and group B (non-treatment group, n = 8). In both groups, total L5–6 laminectomy was performed; further both ligamentum flavum and epidural fat were removed gently. In experimental group, the laminectomy sites were treated with PLGA/CS barriers, while no additional treatment was received in non-treatment group. At 1, 12 and 24 weeks post-surgery, the animals were subjected to magnetic resonance imaging (MRI) evaluation. Following last MRI examination, all rabbits were sacrificed and their spinal columns were totally removed for further macroscopic and histological evaluation. Results: MRI showed that rabbits treated with PLGA/CS barrier at 12 and 24 weeks post-surgery had less epidural fibrosis or scar tissue, peridural adhesion, foreign body reaction and low pressure of spinal cord in comparison with the non-treatment group. In consistence with the radiographic results, macroscopic analysis and histological examination showed that the amount of scar tissue and the extent of epidural adhesion decreased significantly in experimental groups. Concerning the fibroblast density evaluated, the scores were significantly lower in experimental group compared with those in non-treatment group. Conclusion: The results of our study demonstrate that PLGA/CS barrier is effective in inhibiting epidural fibrosis and peridural adhesions in post-laminectomy rabbit model. © 2014, Springer-Verlag Berlin Heidelberg. AD - Department of Orthopedic Surgery, Zhongshan Hospital, Fudan University, Feng Lin Road No. 180, XuHui District, Shanghai, 200032, China Department of General Surgery, Zhongshan Hospital, Fudan University, Feng Lin Road No. 180, XuHui District, Shanghai, 200032, China Department of Orthopedic Surgery, The Affiliated Hospital of Medical College, Qingdao University, Shandong, 266000, China Medical Science & Research Center, Beijing Shijitan Hospital Affilated to Capital Medical University, 10 Tieyi Road, Beijing, 100038, China Department of Polymer Materials, Shanghai University, 99 Shangda Road, Shanghai, 200444, China AU - Li, C. AU - Wang, H. AU - Liu, H. AU - Yin, J. AU - Cui, L. AU - Chen, Z. DB - Scopus DO - 10.1007/s00586-014-3438-0 IS - 11 KW - Epidural fibrosis Failed back surgery syndrome Laminectomy MRI Poly (l-glutamic acid)/chitosan M3 - Article N1 - Cited By :12 Export Date: 10 November 2020 PY - 2014 SP - 2423-2431 ST - The prevention effect of poly (l-glutamic acid)/chitosan on spinal epidural fibrosis and peridural adhesion in the post-laminectomy rabbit model T2 - European Spine Journal TI - The prevention effect of poly (l-glutamic acid)/chitosan on spinal epidural fibrosis and peridural adhesion in the post-laminectomy rabbit model UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84928595795&doi=10.1007%2fs00586-014-3438-0&partnerID=40&md5=51fe3bec88ec6b0cbfa09f36dadd6f40 VL - 23 ID - 1256 ER - TY - JOUR AB - Background: Pyrexia is a physiological response through which the immune system responds to infectious processes. Hyperpyrexia is known to be neurodegenerative leading to brain damage. Some of the neurotoxic effects of hyperpyrexia on the brain include seizures, decreased cognitive speed, mental status changes, coma, and even death. In the clinical management of hyperpyrexia, the goal is to treat the underlying cause of elevated temperature and prevent end organ damage. Case presentation: This case illustrates a 39-year-old white American man referred from another medical facility where he had undergone an upper gastrointestinal tract diagnostic procedure which became complicated by blood aspiration and respiratory distress. During hospitalization, he developed a core body temperature of 41.6 °C (106.9 °F) leading to cognitive decline and coma with a Glasgow Coma Score of 3. Levetiracetam and amantadine were utilized effectively for preserving and restoring neurocognitive function. Prior studies have shown that glutamate levels can increase during an infectious process. Glutamate is an excitatory neurotransmitter that is utilized by the organum vasculosum laminae terminalis through the neuronal excitatory system and causes an increase in body temperature which can lead to hyperpyrexia. Similar to neurogenic fevers, hyperpyrexia can lead to neurological decline and irreversible cognitive dysfunction. Inhibition of the glutamate aids a decrease in excitatory states, and improves the brain's regulatory mechanism, including temperature control. To further improve cognitive function, dopamine levels were increased with a dopamine agonist. Conclusions: We propose that a combination of levetiracetam and amantadine may provide neuroprotective and neurorestorative properties when administered during a period of hyperpyrexia accompanied by any form of mental status changes, particularly if there is a decline in Glasgow Coma Score. © 2017 The Author(s). AD - Department of Internal Medicine, Larkin Community Hospital, Graduate Medical Education, 7000 SW 62nd Avenue, South Miami, FL 33142, United States Department of Psychiatry, Larkin Community Hospital, Graduate Medical Education, 7000 SW 62nd Avenue, South Miami, FL 33142, United States Division of Clinical and Translational Research, Larkin Community Hospital, South Miami, FL, United States AU - Sterkel, S. AU - Akinyemi, A. AU - Sanchez-Gonzalez, M. A. AU - Michel, G. C7 - 40 DB - Scopus DO - 10.1186/s13256-017-1204-8 IS - 1 KW - Amantadine Glasgow Coma Score Glutamate Hyperpyrexia Levetiracetam Neuroprotection Organum vasculosum laminae terminalis M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2017 ST - Preserving brain function in a comatose patient with septic hyperpyrexia (41.6 °C): A case report T2 - Journal of Medical Case Reports TI - Preserving brain function in a comatose patient with septic hyperpyrexia (41.6 °C): A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85012180681&doi=10.1186%2fs13256-017-1204-8&partnerID=40&md5=6728d99750171d4930eca2cd253a7cc4 VL - 11 ID - 1143 ER - TY - JOUR AB - Case report: A 4 y.o. african girl was hospitalized for vaginal bleeding that had started few hours before. Her medical and surgery histories were uneventful. She denied pain, fever, lethargy, abdominal distension or dysuria. She had no history suggestive of sexual abuse, trauma or foreign body to the genital area. The patient was kept by her big siblings during the day without a remarkable event. Her vital signs and physical examination were normal. Tanner: P1S1A1. Examination of the genitalia revealed vaginal blood clot without any local injury. Complete blood count and clotting factors were normal. Further examination wasn't possible at bedside. A cystoscopy and vaginoscopy were done under a general anesthesia. A tumor was found in the urethral inferior lip. No gynecologic disease was observed. Biopsy revealed an overlay with inflammatory and fibrin tissue, and no malignancy. An urethral caruncle was diagnosed. 1 week later urethral inflammation was still present; corticoid cream was prescribed for 2 weeks allowing disappearance of residual mass. Follow up was free of recurrence. Discussion: Common causes of vaginal bleeding in pre-puberty girls are neonatal withdrawal bleeding, trauma, foreign bodies, infections (vulvo-vaginitis / peri-urethral gland abscess), hematuria, urethral prolapse, precocious puberty, tumor and sexual abuse. An exhaustive anamnesis and physical examination, usually under general anesthesia, are crucial for the diagnosis. If a tumor is found, biopsy is required to exclude malignant tumors. Urethral caruncles are usually confined to women urethra and are rarely found in pre-puberty girls. They are present in the urethral meatus and bleeding is the most common symptom, but persistent pain or urination difficulties are also described. Microscopic findings are interstitial oedema with inflammatory cell infiltration and hyperplasia of the connective tissue. Two therapy approaches are possible: steroid ointment (because of chronic inflammation) and/or surgical resection. A potential problem is meatal stenosis. No relapse is described in the literature. Conclusions: Urethral caruncles are one of the rare causes of vaginal bleeding in children. Topical steroids are recommended for a few weeks. If this treatment fails or suspicion of malignancy exists biopsy ± excision is required. Surgery side effect is meatal stenosis and steroid ointment may be required if inflammation (or incomplete resection) persists after surgery. AD - P. Diaz, Service de Pédiatrie, Hôpital du Valais, CHVR, Sion, Switzerland AU - Diaz, P. AU - Llor, J. AU - Russo, M. AU - Cheseaux, J. J. AU - Tabin, R. AU - Alexe, E. AU - Ramseyer, P. DB - Embase KW - corticosteroid endogenous compound fibrin abdominal distension abscess African anamnesis biopsy blood cell count blood clot cancer recurrence cancer surgery case report cell infiltration child chronic inflammation clinical article conference abstract connective tissue cystoscopy drug withdrawal dysuria edema excision female fever follow up foreign body general anesthesia girl hematuria human hyperplasia inflammatory cell lethargy malignant neoplasm newborn ointment physical examination precocious puberty prepuberty relapse sexual abuse sibling side effect stenosis surgery topical drug administration treatment failure urethral prolapse urethritis vagina bleeding vaginitis vital sign withdrawal bleeding LA - English M3 - Conference Abstract N1 - L627022997 2019-04-05 PY - 2017 SN - 1424-3997 SP - 18S-19S ST - Prepubertal girl with vaginal bleeding T2 - Swiss Medical Weekly TI - Prepubertal girl with vaginal bleeding UR - https://www.embase.com/search/results?subaction=viewrecord&id=L627022997&from=export VL - 147 ID - 379 ER - TY - JOUR AB - Background: Von Willebrand disease (VWD) affects approximately 1% of the population and is often diagnosed after the presentation of mucocutaneous bleeding. While heavy menstrual bleeding can be the first sign of a bleeding disorder (BD), prepubertal vaginal bleeding (VB) is more commonly caused by precocious puberty, sexual abuse, foreign body, or vaginitis. We present the case of VB in a prepubertal child who was subsequently diagnosed with VWD. Case: A 7-year-old girl with eczema and constipation presented to clinic reporting VB for 2 days. She denied pain, trauma, exogenous hormone exposure, sexual abuse, or placing objects in the vagina. On exam, she was Tanner stage II for breasts and pubic hair. Brown streaks of dried blood were noted in her underwear, but external genital exam was without abrasions, scars, or bruises. Denuded skin was noted within the gluteal cleft. Given her history, a mild steroid cream was prescribed along with a bowel regimen. Plan was for an exam under anesthesia (EUA) if persistent VB occurred. Workup for precocious puberty was negative. Despite resolution of gluteal skin changes, she presented to the emergency center twice in the following month with complaints of VB and new periumbilical pain. Plan was made for an exam under anesthesia (EUA) and vaginoscopy, but she was lost to follow up for 4 months. Upon representation, symptoms persisted and she was taken for surgery as planned. Vaginoscopy was without foreign body or VB, but was notable for increased mucosal vascularity with a friable appearance. Upon removal of the laryngeal mask airway, she was noted to have significant bleeding from her buccal mucosa and gums. This prompted collection of a coagulation panel, a complete blood count, and a VWD panel. Her VWD panel was abnormal with low VWF Antigen and low VWF Activity Ib. Referral to hematology was placed with subsequent diagnosis of type I VWF. Additional testing revealed mild iron deficiency and her Stimate challenge was consistent with a therapeutic response. She was counseled against NSAID use, and instructed to use stimate for any minor bleeding at home and Humate for any future procedures. Comments: VWD is a BD that causes mucous membrane and skin bleeding symptoms, hemorrhage with surgery and other hemostatic challenges. Prompt and accurate diagnosis in the pediatric and adolescent population is important considering the top cause of morbidity and mortality in this age group is accidental trauma. We present a case of prepubertal VB leading to a diagnosis of VWD. To our knowledge, this is the first time that this type of presentation has been described. It is important to keep BD on the differential especially for unexplained prepubertal VB to aid in prompt diagnosis. AU - Chambers, C. N. AU - Adeyemi-Fowode, O. DB - Embase DO - 10.1016/j.jpag.2019.02.061 IS - 2 KW - antigen desmopressin endogenous compound hormone nonsteroid antiinflammatory agent steroid von Willebrand factor abrasion adolescent anesthesia bleeding disorder blood cell count breast buccal mucosa case report child clinical article conference abstract constipation contusion diagnosis drug therapy eczema emergency health service female follow up foreign body girl hair hematology human intestine iron deficiency laryngeal mask menorrhagia morbidity mortality pain patient referral precocious puberty scar school child sexual abuse skin bleeding surgery treatment response vagina bleeding vaginitis vascularization von Willebrand disease LA - English M3 - Conference Abstract N1 - L2001648047 2019-03-08 PY - 2019 SN - 1873-4332 1083-3188 SP - 217-218 ST - Prepubertal Bleeding as a Presenting Symptom of Von Willebrand Disease: A Case Report T2 - Journal of Pediatric and Adolescent Gynecology TI - Prepubertal Bleeding as a Presenting Symptom of Von Willebrand Disease: A Case Report UR - https://www.embase.com/search/results?subaction=viewrecord&id=L2001648047&from=export http://dx.doi.org/10.1016/j.jpag.2019.02.061 VL - 32 ID - 318 ER - TY - JOUR AB - BACKGROUND: We previously demonstrated that the incorporation of the chemokine CXCL12 into alginate microbeads supported long-term survival of microencapsulated auto-, allo-, and xenogeneic islets in murine models of diabetes without systemic immune suppression. The purpose of this study was to test whether CXCL12 could abrogate foreign body responses (FBRs) against alginate microbeads which were empty or contained autologous islets in healthy nonhuman primates (NHPs; n = 4). METHODS: Two NHPs received intraperitoneal implants of 400 000 alginate microbeads with or without CXCL12, and postimplantation immunological and histopathological changes were evaluated up to 6 months postimplantation. A similar evaluation of autologous islets in CXCL12-containing alginate microbeads was performed in NHPs (n = 2). RESULTS: CXCL12-containing alginate microbeads were associated with a markedly reduced FBR to microbeads. Host responses to microbead implants were minimal, as assessed by clinical observations, blood counts, and chemistry. Evaluation of encapsulated islets was limited by the development of necrotizing pancreatitis after hemipancreatectomy in 1 NHP. A limited number of functioning islets were detectable at 6 months posttransplantation in the second NHP. In general, empty microbeads or islet-containing beads were found to be evenly distributed through the intraperitoneal cavity and did not accumulate in the Pouch of Douglas. CONCLUSIONS: Inclusion of CXCL12 in alginate microbeads minimized localized FBR. The NHP autologous islet implant model had limited utility for excluding inflammatory/immune responses to implanted islets because of the complexity of pancreatic surgery (hemipancreatectomy) before transplantation and the need to microencapsulate and transplant encapsulated autologous islets immediately after pancreatectomy and islet isolation. AD - Department of Infectious Diseases, Vaccine and Immunotherapy Center, Massachusetts General Hospital, Boston, MA. Division of Transplant Surgery, The Pancreas/Islet Transplant Program, Massachusetts General Hospital, Boston, MA. Clinical Islet Program, Surgery School of Medicine, University of California Irvine, Irvine, CA. Department of Surgery, Institute for Cellular Transplantation, University of Arizona, Tucson, AZ. ViCapsys, Inc., Athens, GA. Department of Surgery, University of Minnesota, Minneapolis, MN. Department of Pathology and Medical Biology, University of Groningen, Groningen, The Netherlands. AN - 31165082 AU - Sremac, M. AU - Lei, J. AU - Penson, M. F. E. AU - Schuetz, C. AU - Lakey, J. R. T. AU - Papas, K. K. AU - Varde, P. S. AU - Hering, B. AU - de Vos, P. AU - Brauns, T. AU - Markmann, J. AU - Poznansky, M. C. C2 - PMC6511446 DA - May DO - 10.1097/txd.0000000000000890 DP - NLM ET - 2019/06/06 IS - 5 LA - eng N1 - 2373-8731 Sremac, Marinko Lei, Ji Penson, Madeline F E Schuetz, Christian Lakey, Jonathan R T Papas, Klearchos K Varde, Pushkar S Hering, Bernhard de Vos, Paul Brauns, Timothy Markmann, James Poznansky, Mark C Journal Article Transplant Direct. 2019 Apr 15;5(5):e447. doi: 10.1097/TXD.0000000000000890. eCollection 2019 May. PY - 2019 SN - 2373-8731 (Print) 2373-8731 SP - e447 ST - Preliminary Studies of the Impact of CXCL12 on the Foreign Body Reaction to Pancreatic Islets Microencapsulated in Alginate in Nonhuman Primates T2 - Transplant Direct TI - Preliminary Studies of the Impact of CXCL12 on the Foreign Body Reaction to Pancreatic Islets Microencapsulated in Alginate in Nonhuman Primates VL - 5 ID - 233 ER - TY - JOUR AB - Background: There is limited data on the use of abdominal radiographs in the intra-operative/post-operative period for detection of RFBs. As medical costs rise, hospitals have now planned to decrease reimbursement on conditions acquired during inpatient stays, including “unnecessary” radiologic studies. Objective: To identify the clinical and demographic predictors of RFBs among patients undergoing major abdominal/pelvic surgery and associated costs of detection abdominal radiographs. Materials and methods: Preliminary records of 125 patients who underwent selected abdomino-pelvic procedures from January 2002 to December 2010 at a tertiary-care academic hospital were reviewed. Cross-sectional prevalence study was conducted to identify predictors of RFBs. Results: Median patient age was 47. Median weight was 80 kg. Median estimated blood loss(EBL) was 200cc. The most common procedures were an exploratory laparotomy (33.6%), open hemi-colectomy (22.4%), reopening of recent laparotomy (18.4%) and total abdominal hysterectomy (16.8%). Thirty-one (24.8%) of cases were trauma. Four (3.9%) patients had a RFB. Three RFB cases were trauma laparotomies and one scheduled open hemi-colectomy. Adjusted ORs were calculated for five possible risk factors: Age≥50 y vs. age< 50 y OR=1.70 (P=0.70), weight≥100 kg vs. weight< 100 kg OR=2.50 (P=0.73), EBL≥500cc vs. EBL< 500cc OR=0.82 (P=0.44), exploratory laparotomy (yes vs. no) OR=1.78 (P=0.61), trauma vs. non-trauma case OR=1.11 (P=0.93), and length of surgery (>3hours vs. < 3hours) OR=1.74 (0.66). Conclusions: There were 4 RFBs, 75% were trauma cases. The other variables were not significantly associated with risk of RFBs. A policy on performing “routine” abdominal radiographs after a correct count in major surgery is unwarranted in certain cases. AD - V. Vallabh-Patel, Obstetrics and Gynecology, Texas Tech University Health Science Center/Paul L. Foster School of Medicine, El Paso, TX, United States AU - Vallabh-Patel, V. AU - Appleton, K. AU - Wilson, B. AU - Mulla, Z. AU - Saldivar, J. S. DB - Embase DO - 10.1097/01.IGC.0000422085.58592.d3 KW - patient human surgery X ray film female genital tract cancer society foreign body injury laparotomy weight colon resection hospital procedures risk factor abdominal hysterectomy pelvis hospital patient reimbursement bleeding prevalence major surgery policy risk tertiary health care LA - English M3 - Conference Abstract N1 - L71174342 2013-09-30 PY - 2012 SN - 1048-891X SP - E969 ST - Predictors of retained foreign body among patients undergoing abdominal/pelvic surgery and costs of “routine” abdominal radiographs in their detection T2 - International Journal of Gynecological Cancer TI - Predictors of retained foreign body among patients undergoing abdominal/pelvic surgery and costs of “routine” abdominal radiographs in their detection UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71174342&from=export http://dx.doi.org/10.1097/01.IGC.0000422085.58592.d3 VL - 22 ID - 507 ER - TY - JOUR AD - Assistant nurse manager, OR, Jersey Shore University Medical Center, Neptune, NJ, USA AN - 104849409. Language: English. Entry Date: 20110506. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Double Blind Peer Reviewed AU - Fayngersh, Yuri DB - ccm DO - 10.1097/01.ORN.0000394526.34814.3e DP - EBSCOhost IS - 2 KW - Perioperative Nursing Retained Instruments -- Prevention and Control Surgical Count Procedure Documentation Professional Role Reports Surgical Equipment and Supplies Surgical Site N1 - Nursing; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 101308226. PY - 2011 SN - 1933-3145 SP - 48-48 ST - Practice pointers. Is your count correct? T2 - OR Nurse TI - Practice pointers. Is your count correct? UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104849409&site=ehost-live&scope=site VL - 5 ID - 908 ER - TY - JOUR AB - Objective: Background: Case Report: Conclusions: Rare disease The emergency treatment of a retained foreign body within the urethra and bladder is an uncommon clinical scenario within adult urology. Beyond the medical field, the placement of an object/s into the urethra is known as ‘urethral sounding’ and encompasses a sexual practice performed to heighten arousal and pleasure. The medical literature highlights the morbidity associated with this practice, most commonly when the sounding device can no longer be retrieved by the participant. A case report involving an 18-year-old male requiring endoscopic retrieval of 60 magnetic metal beads intended for the purpose of urethral sounding. The management was uncomplicated and the patient suffered no longterm complications at follow-up. A brief review of the literature reveals 9 reports since 2013 of magnetic beads retained within the bladder following this autoerotic practice in adults. The insertion of multiple small magnetic beads into the urethra is an inadvisable method for use in the practice of urethral sounding due to the lack of non-operative management options. This is due to the high risk of the magnetic beads forming a magnetized cluster once the chain enters the bladder. All cases assessed report successful management with both minimally invasive and open approaches. © Am J Case Rep, 2019. AD - Department of Urology, Royal Surrey County Hospital, Guildford, United Kingdom AU - Lindsay, J. S. DB - Scopus DO - 10.12659/AJCR.919439 KW - Foreign bodies Urologic surgical procedures Urology M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 1841-1844 ST - The practice of ‘urethral sounding’ complicated by retained magnetic beads within the Bladder and Urethra: Diagnosis and review of management T2 - American Journal of Case Reports TI - The practice of ‘urethral sounding’ complicated by retained magnetic beads within the Bladder and Urethra: Diagnosis and review of management UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076348957&doi=10.12659%2fAJCR.919439&partnerID=40&md5=a0f5343281b2034cca4d7228b7ad68e6 VL - 20 ID - 1032 ER - TY - JOUR AB - This study aimed at evaluating the potential effect of gallium-incorporated phosphate-based glasses towards periodontitis-associated bacteria, Porphyromonas gingivalis, and matrix metalloproteinase-13. Periodontitis describes a group of inflammatory diseases of the gingiva and supporting structures of the periodontium. They are initiated by the accumulation of plaque bacteria, such as the putative periodontal pathogen Porphyromonas gingivalis, but the host immune response such as elevated matrix metalloproteinases are the major contributing factor for destruction of periodontal tissues. Antibacterial assays of gallium-incorporated phosphate-based glasses were conducted on Porphyromonas gingivalis ATCC 33277 using disc diffusion assay on fastidious anaerobe agar and liquid broth assay in a modified tryptic soy broth. In vitro study investigated the effect of gallium on purified recombinant human matrix metalloproteinase-13 activity using matrix metalloproteinase assay kit. In vivo biocompatibility of gallium-incorporated phosphate-based glass was evaluated in rats as subcutaneous implants. Antibacterial assay of gallium displayed activity against Porphyromonas gingivalis (inhibition zone of 22 ± 0.5 mm compared with 0 mm for control glass, c-PBG). Gallium in the glass contributed to growth inhibitory effect on Porphyromonas gingivalis (up to 1.30 reductions in log 10 values of the viable counts compared with control) in a modified tryptic soy broth. In vitro study showed gallium-incorporated phosphate-based glasses inhibited matrix metalloproteinase activity significantly (p ≤ 0.01) compared with c-PBG. Evaluation of in vivo biocompatibility of gallium-incorporated phosphate-based glasses in rats showed a non-toxic and foreign body response after 2 weeks of implantation. The results indicate that gallium ions might act on multiple targets of biological mechanisms underlying periodontal disease. Moreover, gallium-incorporated phosphate-based glasses are biocompatible in a rat model. The findings warrant further investigation and will have important clinical implications in the future treatment and management of periodontitis. AD - Department of Health Services Research and School of Dentistry, University of Liverpool, Liverpool, UK. Department of Surgical Research, Imperial College London, Watford Road, Harrow, UK. Department of Health Services Research and School of Dentistry, University of Liverpool, Liverpool, UK S.Valappil@iverpool.ac.uk. AN - 25681404 AU - Sahdev, R. AU - Ansari, T. I. AU - Higham, S. M. AU - Valappil, S. P. DA - Jul DO - 10.1177/0885328215571952 DP - NLM ET - 2015/02/15 IS - 1 KW - Animals Anti-Bacterial Agents/administration & dosage/*pharmacology Bacteroidaceae Infections/*drug therapy/immunology/microbiology Biocompatible Materials/*chemistry Gallium/administration & dosage/*pharmacology Glass/chemistry Humans Male Matrix Metalloproteinase 13/immunology Matrix Metalloproteinase Inhibitors/administration & dosage/pharmacology Periodontitis/*drug therapy/immunology/microbiology Phosphates/*chemistry Porphyromonas gingivalis/*drug effects Rats Rats, Sprague-Dawley Gallium Porphyromonas gingivalis matrix metalloproteinase periodontitis phosphate-based glasses LA - eng N1 - 1530-8022 Sahdev, Rohan Ansari, Tahera I Higham, Susan M Valappil, Sabeel P Journal Article Research Support, Non-U.S. Gov't England J Biomater Appl. 2015 Jul;30(1):85-92. doi: 10.1177/0885328215571952. Epub 2015 Feb 12. PY - 2015 SN - 0885-3282 SP - 85-92 ST - Potential use of gallium-doped phosphate-based glass material for periodontitis treatment T2 - J Biomater Appl TI - Potential use of gallium-doped phosphate-based glass material for periodontitis treatment VL - 30 ID - 158 ER - TY - JOUR AB - A 55-year-old white man presented with orbital cellulitis and suspicion of an intraorbital foreign body after ocular trauma. He underwent orbital exploration, but no intraorbital foreign bodies were identified. Intraoperative orbital and conjunctival cultures grew Yersinia enterocolitica O:8. The patient's signs and symptoms resolved with intravenous antibiotic treatment after this exploratory orbitotomy. This is the first case, to our knowledge, of human orbital cellulitis caused by Y. enterocolitica O:8. The single visible interpalpebral conjunctival ulceration was suspected to be an entry wound by the patient's primary physician, the emergency room physician, and the orbital surgeon prior to surgical investigation, at which time all the other ulcerations were identified. Therefore, the physical manifestations of this rare but important infection are presented because they may mislead clinicians in suspecting an intraorbital foreign body. ©2008 The American Society of Opthalmic Plastic and Reconstructive Surgery, Inc. AD - Ophthalmic Plastic Surgery, Albany Medical Center, Lions Eye Institute, 1220 New Scotland Avenue, Albany, NY 12159, United States AU - Mills, D. M. AU - Meyer, D. R. DB - Scopus DO - 10.1097/IOP.0b013e318185511f IS - 5 M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2008 SP - 425-426 ST - Posttraumatic cellulitis and ulcerative conjunctivitis caused by Yersinia enterocolitica O:8 T2 - Ophthalmic Plastic and Reconstructive Surgery TI - Posttraumatic cellulitis and ulcerative conjunctivitis caused by Yersinia enterocolitica O:8 UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-52649108220&doi=10.1097%2fIOP.0b013e318185511f&partnerID=40&md5=3fde2db9fbcbc3d0452bbef53fc01dcf VL - 24 ID - 1515 ER - TY - JOUR AB - Background: The peritoneum is one of the most common extrapulmonary sites of tuberculous infection. Peritoneal tuberculosis remains a significant problem in parts of the world where tuberculosis is prevalent. Tuberculous peritonitis is a rare condition especially in the post-partum era. We report a case of postpartum tuberculous peritonitis mimicking a malignant tumor. Methods & Materials: We report a case of postpartum tuberculous peritonitis mimicking a malignant tumor. 26 year old lady who had a cesarean section 50 days ago presented with ascites and elevated serum CA125 (420 U/ml). In her past story she had another sectio-cesarean 13 months ago and her son was healthy. She had mild anemia with hemoglobin 11 gr/ml with moderately high wbc count. (11300/mm3) Her blood biochemical profile was normal.The viral hepatitis and the HIV profile was negative. Ascidic fluid “ascites-albumin gradient” was lower than 1.1 excluding portal hypertension. Chest X-ray findings did not indicate pulmonary tuberculosis, and neither the smear method nor culture in ascitic fluid obtained by paracentesis indicated an infection of Mycobacterium tuberculosis. Abdominal ultrasound, thorax and abdominal CT revealed massive ascites, mild plevral effusion and servical conglomerated lymphadenopathy of 4X4 cm. The ovaries were normal in CT findings. The ascites fluid had marked lymphocytes and some foreign body particules whichwasthought to be the suture material resolving after the cesarean operation. Results: Ascites fluid adenosine deaminase levels were markedly high. (65 IU/ml) The cervical conglomerated lymph nodes were taken out for pathological examination. Pathologic examination revealed tuberculosis lymphadenitis with marked caseification necrosis. The case was thought to be tuberculosis peritonitis and lymphadenitis. Conclusion: Following treatment using the 4-drug antituberculosis regimen of isoniasid, rifampicin, ethambutol and pyrazinamide; the patient recovered with disappearance of ascites and the CA125 serum level returned to the normal range after six months. AD - I. Tuzcuoglu, Merkez Efendi State Hospital, Manisa, Turkey AU - Tuzcuoglu, I. DB - Embase DO - 10.1016/j.ijid.2014.03.1058 KW - pyrazinamide hemoglobin albumin adenosine deaminase suture material rifampicin ethambutol tuberculous peritonitis ascites serum infection tuberculosis ascites fluid malignant neoplasm examination lymphadenitis female virus hepatitis cesarean section thorax Mycobacterium tuberculosis ovary lymphocyte paracentesis blood leukocyte count lung tuberculosis human smear thorax radiography son ultrasound effusion lymphadenopathy portal hypertension lymph node foreign body necrosis peritonitis liquid anemia patient blood level peritoneum Human immunodeficiency virus LA - English M3 - Conference Abstract N1 - L71634394 2014-10-04 PY - 2014 SN - 1201-9712 SP - 308 ST - Postpartum tuberculous peritonitis with ascites and elevated serum CA125 T2 - International Journal of Infectious Diseases TI - Postpartum tuberculous peritonitis with ascites and elevated serum CA125 UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71634394&from=export http://dx.doi.org/10.1016/j.ijid.2014.03.1058 VL - 21 ID - 453 ER - TY - JOUR AB - BACKGROUND: Textile materials of surgical origin are found in the abdominal cavity in between 1/1300 and 1/1500 laparotomies, in spite of preventive measures. It is very difficult to ascertain the exact incidence due to the lack of descriptions in the literature. METHODS: Fourteen cases of postoperative foreign bodies or textilomas are reported. The cases were collected from two hospital centers between 1985 and 1997. RESULTS: There were 12 intra-abdominal cases, 1 thoracic and 1 paravertebral. In 8 (57.1%) diagnosis was made preoperatively by radiological techniques. The mortality rate was 14.2% with 2 deaths due to multiorganic failure in one case and sepsis in the other. Both patients were over 70, with malignant pathology. The morbidity rate was 21.4%, wall abscesses which evolved favorably being the most frequent cause of complications. CONCLUSIONS: Prevention of this complication is the best treatment. It is advisable to use textile material with radiopaque contrast, to count the pieces of material to be used and perform an X-ray before the laparotomy is closed specially in emergency (bleeding and trauma patients) because in these complex cases the possibility of material being left behind is more advisable. AD - Service of General Surgery, University Hospital of Getafe, Madrid, Spain. AN - 9706523 AU - Fernandez Lobato, R. AU - Marin Lucas, F. J. AU - Fradejas Lopez, J. M. AU - Diaz Gimenez, L. M. AU - Camarero Marina, E. AU - Moreno Azcoita, M. DA - Jan-Mar DP - NLM ET - 1998/08/26 IS - 1 KW - Adult Aged Female Granuloma, Foreign-Body/diagnosis/*etiology/mortality/*surgery Humans Iatrogenic Disease Laparoscopy Male Middle Aged Postoperative Complications/*etiology Retrospective Studies *Textiles Tomography, X-Ray Computed LA - eng N1 - Fernandez Lobato, R Marin Lucas, F J Fradejas Lopez, J M Diaz Gimenez, L M Camarero Marina, E Moreno Azcoita, M Journal Article Review Italy Int Surg. 1998 Jan-Mar;83(1):63-6. PY - 1998 SN - 0020-8868 (Print) 0020-8868 SP - 63-6 ST - Postoperative textilomas: review of 14 cases T2 - Int Surg TI - Postoperative textilomas: review of 14 cases VL - 83 ID - 27 ER - TY - JOUR AB - Background: Extracorporeal circulation is associated with systemic inflammatory response syndrome. Therefore, the diagnosis of infection should be differentiated from a typical postoperative course. Aim: The aim of the study was to evaluate the kinetics of inflammatory biomarkers in children in the first days after cardiac surgery with extracorporeal circulation. Methods: Prospective data were collected from 51 consecutive children referred for surgical treatment in Department of Paediatric Cardiac Surgery, St. Adalbertus Hospital in Gdañsk, between February and August 2015. Blood samples were collected on the first, second, and third postoperative days and sent to the institutional laboratory for routine investigations: White blood cell count, serum C-reactive protein (CRP) and procalcitonin concentrations. Results: The highest levels of procalcitonin were on the first postoperative day (median 3.53 ng/mL), although the peak values of CRP concentration and white blood cell count were on the second postoperative day (96 mg/L and 17.3 G/L). In the group of patients with foreign material implantation (Contegra(r) or Gore-Tex(r)), the higher values of procalcitonin concentration and white blood cell count were measured in the subsequent postoperative days. Conclusions: The kinetics of analysed inflammatory biomarkers on the first days after cardiac surgery for congenital heart disease in children have different characteristics. The knowledge about the kinetics of inflammatory biomarkers could be useful in determining the possibility of evolving infections in the early postoperative period. AD - I. Haponiuk, Department of Paediatric Cardiac Surgery, St. Adalbertus Hospital, Al. Jana Pawła II 50, Gdansk, Poland AU - Haponiuk, I. AU - Jaworski, R. AU - Paczkowski, K. AU - Chojnicki, M. AU - Steffens, M. AU - Szofer-Sendrowska, A. AU - Gierat-Haponiuk, K. AU - Kwaśniak, E. AU - Paśko-Majewska, M. AU - Leszczyñska, K. AU - Zieliñski, J. AU - Szymanowicz, W. DB - Embase Medline DO - 10.5603/KP.a2018.0038 IS - 6 KW - pulmonary valved conduit politef immunoassay analyzer Modular Roche A PB 06-76 politef implant roller pump Sorin S5 biological marker C reactive protein cefazolin procalcitonin antibiotic prophylaxis article atrioventricular septal defect blood sampling calcitonin blood level child congenital heart malformation deep hypothermic circulatory arrest extracorporeal circulation Fallot tetralogy female Fontan procedure foreign body great vessels transposition heart atrium septum defect heart surgery heart ventricle septum defect human immunoturbidimetry infant leukocyte count major clinical study male maximum plasma concentration newborn pediatric surgery postoperative care prospective study protein blood level surgical infection systemic inflammatory response syndrome Contegra Gore-Tex LA - English M3 - Article N1 - L622526457 2018-06-15 2019-06-13 PY - 2018 SN - 1897-4279 0022-9032 SP - 968-973 ST - Postoperative kinetics of common inflammatory biomarkers after congenital heart defect procedures with extracorporeal circulation in children T2 - Kardiologia Polska TI - Postoperative kinetics of common inflammatory biomarkers after congenital heart defect procedures with extracorporeal circulation in children UR - https://www.embase.com/search/results?subaction=viewrecord&id=L622526457&from=export http://dx.doi.org/10.5603/KP.a2018.0038 VL - 76 ID - 344 ER - TY - JOUR AB - Objective. The purpose of this study was to assess and compare inflammatory reactions to two types of sealed vascular prostheses used in the repair of abdominal aortic aneurysm. Experimental design. Randomized prospective study with a follow-up period of 21 days. Setting. University hospital study. Patients. Sixty patients admitted for elective abdominal aortic aneurysm repair. Intervention. Each patient underwent repair of abdominal aortic aneurysm with either a gelatin-sealed knitted Dacron prosthesis (Gelseal®, Vascutek, n = 30) or a collagen-sealed woven Dacron prosthesis (Hemashield®, Meadox Medicals, n = 30). Measures. As indicators of the presence of inflammation, the peripheral blood cell count, platelet count, and plasma C-reactive protein (CRP) concentration were determined in each patient on postoperative days (PODs) 1, 7, 14 and 21. Body temperature was measured every 8 hours. Results. Patients in both groups revealed a low-grade fever and leukocytosis during the first 7 PODs. Significantly higher leukocyte counts were demonstrated in the Gelseal group on PODs 7 and 14. However, no difference in the leukocyte count, CRP concentration, or body temperature existed between the two groups on POD 21. Biphasis changes in the platelet count were observed in both groups. No complications were encountered. Conclusion. The Gelseal prosthesis was associated with higher inflammatory response during the second week following implantation, but this difference had resolved by POD 21. This finding may reflect an inflammatory reaction against impregnated gelatin. AD - First Department of Surgery, Kumamoto University, School of Medicine, 1-1-1 Honjo, Kumamoto City, Kumamoto 860, Japan AU - Utoh, J. AU - Goto, H. AU - Hirata, T. AU - Hara, M. AU - Kitamura, N. DB - Scopus IS - 3 KW - Blood vessels Polyethylene terephthalate Prosthesis M3 - Article N1 - Cited By :12 Export Date: 10 November 2020 PY - 1997 SP - 287-290 ST - Postoperative inflammatory reactions to sealed Dracon prostheses. A comparison of Gelseal® and Hemashield® T2 - Journal of Cardiovascular Surgery TI - Postoperative inflammatory reactions to sealed Dracon prostheses. A comparison of Gelseal® and Hemashield® UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030757341&partnerID=40&md5=2d8fb0650999d09c5698f796982a4442 VL - 38 ID - 1704 ER - TY - JOUR AB - Purpose: To evaluate the influence on postoperative inflammation of lens epithelial cell (LEO) removal after phacoemulsification. Setting: Department of Ophthalmology, University of Vienna, Vienna, Austria. Methods: This randomized prospective single-surgeon study comprised 60 patients with senile cataract only. After a temporal clear corneal incision was made and phacoemulsification performed, no LEOs were removed in Group A, LEOs in the nasal half were removed in Group B, and LEOs were removed from the entire anterior capsule in Group C. The LEOs were removed with a Rentsch capsule curette (Geuder). In all eyes, a foldable hydrogel intraocular lens (Hydroview®, Bausch & Lomb) was implanted. Anterior chamber flare was evaluated through dilated pupils in a double-masked fashion using a Kowa FC-1000 laser flare-cell meter (LFCM). Measurements were done preoperatively as well as 1, 3, 7, 14, and 28 days and 3, 6, 12, and 24 months postoperatively. Results: In all 3 groups, the flare and cell values increased on the first postoperative day followed by a successive decrease thereafter. One month after surgery, the bloodaqueous barrier (BAB) was nearly restored in all groups. Between the first and fourth week, the flare values in Groups B and C were slightly lower than in Group A; however, mean flare and cell values among groups were not statistically significantly different at any measurement. Conclusion: The removal of LEOs from the anterior capsule with a Rentsch curette did not influence postoperative BAB changes detected using an LFCM. © 2001 ASCRS and ESCRS. AD - Department of Ophthalmology, University of Vienna, Medical School, Waehringer Guertel 18-20, A-1090 Vienna, Austria Department of Ophthalmology, University of Vienna, Vienna, Austria AU - Kruger, A. J. AU - Amon, M. AU - Abela-Formanek, C. AU - Schild, G. AU - Kolodjaschna, J. AU - Schauersberger, J. DB - Scopus DO - 10.1016/S0886-3350(01)00795-7 IS - 9 M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2001 SP - 1380-1385 ST - Postoperative inflammation after lens epithelial cell removal: 2 Year results T2 - Journal of Cataract and Refractive Surgery TI - Postoperative inflammation after lens epithelial cell removal: 2 Year results UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034820512&doi=10.1016%2fS0886-3350%2801%2900795-7&partnerID=40&md5=3c8f511e5ff2287e279eea38f098ff60 VL - 27 ID - 1668 ER - TY - JOUR AB - Purpose: The aim of this prospective observational study was to evaluate the incidence of postoperative bleeding after dental extraction in candidates for liver transplantation and the efficacy of the association of tranexamic acid and absorbable hemostatic sponges. Patients and Methods: All individuals referred for oral health evaluation requiring extraction were considered in this study. Patients were included in the analysis when the blood examinations showed a platelet count of 30,000/mm3 or greater and an international normalized ratio (INR) of 3.0 or less. In group 1 local pressure was applied by use of gauze soaked with tranexamic acid, and in group 2 gauze without tranexamic acid was used. Absorbable hemostatic sponges and cross sutures were used as a standard hemostatic measure. Results: In the 23 patients included in this study, 84 simple extractions were performed during 35 dental surgical procedures. The main preoperative blood tests found the following: a mean hematocrit level of 34.54% (SD, 5.84%; range, 21.7%-44.4%), platelet counts from 31,000/mm3 to 160,000/mm3, and a mean INR of 1.50 (SD, 0.39; range, 0.98-2.59). Postoperative bleeding occurred during only 1 procedure (2.9%), and local pressure with gauze was effective for achieving hemostasis. No statistically significant difference in the time to hemostasis was found between the 2 groups. Conclusions: This study found a low risk of bleeding for tooth extractions in patients with liver cirrhosis, INRs of 2.50 or less, and platelet counts of 30,000/mm3 or greater. Blood transfusions were not needed, and in the case of postoperative bleeding, the use of local hemostatic measures was satisfactory. © 2012 American Association of Oral and Maxillofacial Surgeons. AD - F.B. Sousa, Rua Monsenhor Furtado, Universidade Federal do Ceará, Programa de Pós-Graduação em Odontologia, Curso de Odontologia, Fortaleza/CE 60.430-350, Brazil AU - Perdigão, J. P. V. AU - De Almeida, P. C. AU - Rocha, T. D. S. AU - Mota, M. R. L. AU - Soares, E. C. S. AU - Alves, A. P. N. N. AU - Sousa, F. B. DB - Embase Medline DO - 10.1016/j.joms.2011.10.033 IS - 3 KW - dipyrone paracetamol tranexamic acid absorbable hemostatic sponge adult aged article blood sampling controlled study cross-sectional study female gauze dressing hemostasis human incidence international normalized ratio liver transplantation major clinical study male observational study postoperative hemorrhage postoperative pain preoperative period prospective study surgical sponge therapy effect platelet count tooth extraction LA - English M3 - Article N1 - L365574175 2012-09-12 2012-09-18 PY - 2012 SN - 0278-2391 1531-5053 SP - e177-e184 ST - Postoperative bleeding after dental extraction in liver pretransplant patients T2 - Journal of Oral and Maxillofacial Surgery TI - Postoperative bleeding after dental extraction in liver pretransplant patients UR - https://www.embase.com/search/results?subaction=viewrecord&id=L365574175&from=export http://dx.doi.org/10.1016/j.joms.2011.10.033 VL - 70 ID - 520 ER - TY - JOUR AB - Purpose. Post-traumatic endophthalmitis makes up a distinct subset of intraocular infections. The purpose of the present study was to identify the causative organisms and record the visual outcome after infectious endophthalmitis in eyes with penetrating trauma. Methods. We reviewed 18 consecutive cases of culture-positive endophthalmitis that developed after penetrating ocular trauma. All cases were treated with pars plana vitrectomy and intravenous and intraocular antibiotics. Results. The 15 males and 3 females ranged in age from 4 to 43 years (mean 25.1 ± 11 years). Nine (50%) had intraocular foreign bodies. A single species was isolated in 16 cases, and multiple organisms in two. Staphylococcus epidermidis and gram-negative organisms were the most frequent and were cultured either alone or in association with other organisms in respectively five (27.7%) and four cases (22.2%). Clostridium perfringens was isolated in three cases (16.6%). Bacillus was not found as a cause of endophthalmitis. Final visual acuity was better than 20/400 in eight cases (44%). In five cases (27.7%), the eye was saved but visual acuity was counting fingers. Two eyes (11%) had no light perception. The remaining three eyes (16.6%) were enucleated or eviscerated. Clostridium perfringens was isolated from two eyes and Aspergillus niger from one. Postoperative retinal detachment developed in four eyes, which were successfully operated. Conclusions. Organisms isolated in this series were similar to those in previous reports of post-traumatic endophthalmitis from other parts of the world, except that the frequency of Clostridium perfringens isolation was high and no Bacillus species were cultured. In view of its devastating outcome, post-traumatic endophthalmitis must be treated promptly with vitrectomy and intravitreal antibiotics. AD - A.M.A. El-Asrar, Department of Ophthalmology, King Abdulaziz University Hospital, Airport Road, Riyadh 11411, Saudi Arabia AU - Abu El-Asrar, A. M. AU - Al-Amro, S. A. AU - Al-Mosallam, A. A. AU - Al-Obeidan, S. DB - Embase Medline DO - 10.1177/112067219900900104 IS - 1 KW - antibiotic agent cefazolin gentamicin prednisone triamcinolone vancomycin adult antibiotic therapy article Aspergillus niger clinical article Clostridium perfringens endophthalmitis enucleation evisceration eye injury female Gram negative bacterium human intraocular drug administration intraocular foreign body intravenous drug administration intravitreal drug administration male penetrating trauma postoperative complication priority journal retina detachment Staphylococcus epidermidis visual acuity vitrectomy LA - English M3 - Article N1 - L29179942 1999-05-16 PY - 1999 SN - 1120-6721 SP - 21-31 ST - Post-traumatic endophthalmitis: Causative organisms and visual outcome T2 - European Journal of Ophthalmology TI - Post-traumatic endophthalmitis: Causative organisms and visual outcome UR - https://www.embase.com/search/results?subaction=viewrecord&id=L29179942&from=export http://dx.doi.org/10.1177/112067219900900104 VL - 9 ID - 657 ER - TY - JOUR AB - Purpose: Knowledge about the influence of underlying biomaterial on behavior of surgical meshes at the esophageal hiatus is rare, but essential for safe and effective hiatal hernia surgery. This study aimed to characterize the influence of polymer material on mesh behavior at the hiatus.Methods: 24 pigs in three groups of eight underwent implantation of either polypropylene (PP), polyester (PET) or polytetrafluoroethylene (PTFE) mesh placed circularly at the esophageal hiatus. After 8 weeks, necropsy and measurements were performed evaluating mesh deformation, adhesion formation, fixation of the esophagogastric junction and mesh position. Foreign body reaction was assessed by mononuclear cell count and immunostaining of Ki-67. Tissue integration was evaluated by immunostaining of type I and type III collagen fibers.Results: Mesh shrinkage was the highest for PTFE, lower for PP and the lowest for PET (34.9 vs. 19.8 vs. 12.1 %; p = 0.002). Mesh aperture for the esophagus showed an enlargement within all groups, which was highest for PTFE compared to PP and PET (100.8 vs. 47.0 vs. 35.9 %; p = 0.001). The adhesion score was highest for PP, lower for PTFE and the lowest for PET (11.0 vs. 9.5 vs. 5.0; p = 0.001) and correlated positively with the score of esophagogastric fixation (r s = 0.784, p < 0.001). No mesh migration, erosion or stenosis of the esophagus occurred. Evaluation of foreign body reaction and tissue integration showed no significant differences.Conclusions: In this experimental setting, PP-meshes showed the most appropriate characteristics for augmentation at the hiatus. Due to solid fixation of the esophagogastric junction and low shrinkage tendency, PP-meshes may be effective in preventing hiatal hernia recurrence. The use of PTFE-mesh at the hiatus may be disadvantageous due to high shrinkage rates and correlating enlargement of the aperture for the esophagus. AN - 109765800. Language: English. Entry Date: 20150821. Revision Date: 20200708. Publication Type: journal article AU - Müller-Stich, B. P. AU - Senft, J. D. AU - Lasitschka, F. AU - Shevchenko, M. AU - Billeter, A. T. AU - Bruckner, T. AU - Kenngott, H. G. AU - Fischer, L. AU - Gehrig, T. DB - ccm DO - 10.1007/s10029-014-1305-x DP - EBSCOhost IS - 6 KW - Esophagus -- Surgery Hernia, Diaphragmatic -- Surgery Surgical Mesh Animal Studies Biocompatible Materials Materials Testing Models, Biological Polyenes Polyesters Polytetrafluoroethylene Swine N1 - research. Journal Subset: Biomedical; Blind Peer Reviewed; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. NLM UID: 9715168. PMID: NLM25159558. PY - 2014 SN - 1265-4906 SP - 873-881 ST - Polypropylene, polyester or polytetrafluoroethylene-is there an ideal material for mesh augmentation at the esophageal hiatus? Results from an experimental study in a porcine model T2 - Hernia TI - Polypropylene, polyester or polytetrafluoroethylene-is there an ideal material for mesh augmentation at the esophageal hiatus? Results from an experimental study in a porcine model UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109765800&site=ehost-live&scope=site VL - 18 ID - 792 ER - TY - JOUR AB - We describe a case of polymicrobial bacterial pericarditis with Klebsiella pneumoniae and Proteus mirabilis, caused by pericardial penetration of the tip of the catheter of a laparoscopic adjustable gastric band (LAGB). The patient developed a cardiac tamponade, and subsequently emergency pericardiocentesis was performed. Analysis of earlier CT scans showed that the tip of the catheter had migrated through the liver and through the diaphragm into the pericardium, and was in contact with the myocardium. After stabilisation he was operated to remove the LAGB. In this case report, we describe the chain of events that led to the polymicrobial pericarditis - a complication of LAGB placement that to our knowledge has thus far never been reported. We furthermore present a detailed literature review of all published cases of polymicrobial pericarditis and its causes. © 2018 BMJ Publishing Group Ltd. All rights reserved. AD - Department of Internal Medicine, Haaglanden Medical Centrum, The Hague, Netherlands Department of Radiology, Haaglanden Medical Centrum, The Hague, Netherlands Department of Bariatric Surgery, Groene Hart Hospital, Gouda, Netherlands Department of Medical Microbiology, Haaglanden Medical Centrum, The Hague, Netherlands Department of Cardiology, Haaglanden Medical Centrum, The Hague, Netherlands AU - De Jong, Y. AU - Van Loenhout, R. B. AU - Swank, D. J. AU - Jansen, C. L. AU - Sorgdrager, B. J. C7 - bcr-2017-221589 DB - Scopus DO - 10.1136/bcr-2017-221589 KW - emergency medicine gastroenterology gastrointestinal surgery interventional cardiology M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 ST - Polymicrobial bacterial pericarditis and cardiac tamponade caused by pericardial penetration of an adjustable gastric band T2 - BMJ Case Reports TI - Polymicrobial bacterial pericarditis and cardiac tamponade caused by pericardial penetration of an adjustable gastric band UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85042296047&doi=10.1136%2fbcr-2017-221589&partnerID=40&md5=1a68b1ea41a1b940d64ab23905de764e VL - 2018 ID - 1102 ER - TY - JOUR AB - Synovial fluid from the knees of 16 patients undergoing revision knee arthroplasty for aseptic failure was subjected to base digestion and ultrafiltration. Filtered particles were scanned using scanning electron microscopy and analyzed with an image program. Polyethylene particles were identified visually and confirmed with the use of electron diffraction spectroscopy. Averaging more than 1500 particles per patient sample, 25,148 particles were analyzed. This corresponded to a concentration of 3000 polyethylene particles per milliliter of synovial fluid. Three populations of wear debris were identified in the fluid. Small globular particles with a mean area of 75 mu 2 represented 94% of all particles observed. The particles averaged 10 mu in diameter and often were seen in clumps. Long fibrous particles with a mean area of 1164 mu 2 made up 4% of the particle population. Large rhomboidal particles with an area of 557 mu 2 were observed least commonly and comprised the remainder of the particles visualized. All three particle types were observed in each fluid sample regardless of the wear pattern of the retrieved polyethylene liner. There were no differences in absolute particle counts, particle morphologic characteristics, or particle size between patients with and without gross polyethylene wear. AD - Orthopedic Research Laboratory, University of Arizona Health Sciences Center, Tucson 85719, USA. AN - 10078140 AU - Peterson, C. AU - Benjamin, J. B. AU - Szivek, J. A. AU - Anderson, P. L. AU - Shriki, J. AU - Wong, M. DA - Feb DO - 10.1097/00003086-199902000-00018 DP - NLM ET - 1999/03/17 IS - 359 KW - Aged Aged, 80 and over Equipment Failure Analysis Female Foreign Bodies/*pathology Humans *Knee Prosthesis Male Microscopy, Electron, Scanning Middle Aged Osteonecrosis/*pathology/surgery Particle Size Polyethylenes/*analysis Postoperative Complications/*pathology/surgery Reoperation Synovial Fluid/*chemistry LA - eng N1 - Peterson, C Benjamin, J B Szivek, J A Anderson, P L Shriki, J Wong, M Journal Article United States Clin Orthop Relat Res. 1999 Feb;(359):167-75. doi: 10.1097/00003086-199902000-00018. PY - 1999 SN - 0009-921X (Print) 0009-921x SP - 167-75 ST - Polyethylene particle morphology in synovial fluid of failed knee arthroplasty T2 - Clin Orthop Relat Res TI - Polyethylene particle morphology in synovial fluid of failed knee arthroplasty ID - 28 ER - TY - JOUR AB - Poly(3-hydroxybutyrate) (P(3HB)) foams exhibiting highly interconnected porosity (85% porosity) were prepared using a unique combination of solvent casting and particulate leaching techniques by employing commercially available sugar cubes as porogen. Bioactive glass (BG) particles of 45S5 Bioglass® grade were introduced in the scaffold microstructure, both in micrometer ((m-BG), <5 μm) and nanometer ((n-BG), 30 nm) sizes. The in vitro bioactivity of the P(3HB)/BG foams was confirmed within 10 days of immersion in simulated body fluid and the foams showed high level of protein adsorption. The foams interconnected porous microstructure proved to be suitable for MG-63 osteoblast cell attachment and proliferation. The foams implanted in rats as subcutaneous implants resulted in a non-toxic and foreign body response after one week of implantation. In addition to showing bioactivity and biocompatibility, the P(3HB)/BG composite foams also exhibited bactericidal properties, which was tested on the growth of Staphylococcus aureus. An attempt was made at developing multifunctional scaffolds by incorporating, in addition to BG, selected concentrations of Vitamin E or/and carbon nanotubes. P(3HB) scaffolds with multifunctionalities (viz. bactericidal, bioactive, electrically conductive, antioxidative behaviour) were thus produced, which paves the way for next generation of advanced scaffolds for bone tissue engineering. © 2009 Elsevier Ltd. All rights reserved. AD - Department of Materials, Imperial College London, Exhibition Road, London, SW7 2AZ, United Kingdom Natural History Museum, Mineralogy, Cromwell Road, London, SW7 5BD, United Kingdom Department of Surgical Research, Northwick Park Institute of Medical Research, Northwick Park Hospital, Harrow, HA1 3UJ, United Kingdom School of Dental Sciences, University of Liverpool, Liverpool, L69 3GN, United Kingdom Institute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland Department of Molecular and Applied Biosciences, University of Westminster, New Cavendish Road, London, W1W 6UW, United Kingdom Division of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, 256 Grays Inn Road, London, WC1X 8LD, United Kingdom Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, 91058 Erlangen, Germany AU - Misra, S. K. AU - Ansari, T. I. AU - Valappil, S. P. AU - Mohn, D. AU - Philip, S. E. AU - Stark, W. J. AU - Roy, I. AU - Knowles, J. C. AU - Salih, V. AU - Boccaccini, A. R. DB - Scopus DO - 10.1016/j.biomaterials.2009.12.045 IS - 10 KW - Bioactive glass Bone tissue engineering Carbon nanotubes Composite materials Poly(3-hydroxybutyrate) Scaffolds M3 - Article N1 - Cited By :127 Export Date: 10 November 2020 PY - 2010 SP - 2806-2815 ST - Poly(3-hydroxybutyrate) multifunctional composite scaffolds for tissue engineering applications T2 - Biomaterials TI - Poly(3-hydroxybutyrate) multifunctional composite scaffolds for tissue engineering applications UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-75149150824&doi=10.1016%2fj.biomaterials.2009.12.045&partnerID=40&md5=c182eff645a8f35a1fc769c59cc1eba6 VL - 31 ID - 1464 ER - TY - JOUR AB - Background. Policies for sponge count are not routine practice in most labor and delivery rooms. Ignored or hidden retained vaginal foreign bodies has potentially significant health care morbidity. Case. This was a case of a retained vaginal sponge following an uncomplicated spontaneous vaginal delivery. Delivery room policy resulted in the discovery of the sponge on X-ray when an incorrect sponge count occurred and physical exam did not find the sponge. Conclusion. This emphasizes the use of protocols to enhance patient safety and prevent medical error. © Copyright 2012 David J. Garry et al. AD - D.J. Garry, Department of Obstetrics, Gynecology and Womens Health, Jacobi Medical Center, Yeshiva University, 1400 Pelham Parkway South, Bronx, NY 10461, United States AU - Garry, D. J. AU - Asanjarani, S. AU - Geiss, D. M. DB - Embase DO - 10.1155/2012/317856 KW - azithromycin oxytocin adolescent article case report Chlamydia delivery room epidural anesthesia epidural catheter female foreign body health care policy human labor induction laceration maternal morbidity medical error oligohydramnios patient safety pelvis radiography periurethral laceration physical examination prenatal care priority journal retained instrument retained sponge surgical sponge uterine cervicitis vagina laceration vaginal delivery LA - English M3 - Article N1 - L364536049 2012-04-05 2012-04-11 PY - 2012 SN - 1687-9635 1687-9627 ST - Policy for prevention of a retained sponge after vaginal delivery T2 - Case Reports in Medicine TI - Policy for prevention of a retained sponge after vaginal delivery UR - https://www.embase.com/search/results?subaction=viewrecord&id=L364536049&from=export http://dx.doi.org/10.1155/2012/317856 VL - 2012 ID - 527 ER - TY - JOUR AB - The inability of the avascular region of the meniscus to regenerate has led to the use of tissue engineering to treat meniscal injuries. The aim of this study was to evaluate the ability of fibrochondrocytes preseeded on PLDLA/PCL-T [poly(L-co-D,L-lactic acid)/poly(caprolactone-triol)] scaffolds to stimulate regeneration of the whole meniscus. Porous PLDLA/PCL-T (90/10) scaffolds were obtained by solvent casting and particulate leaching. Compressive modulus of 9.5±1.0 MPa and maximum stress of 4.7±0.9 MPa were evaluated. Fibrochondrocytes from rabbit menisci were isolated, seeded directly on the scaffolds, and cultured for 21 days. New Zealand rabbits underwent total meniscectomy, after which implants consisting of cell-free scaffolds or cell-seeded scaffolds were introduced into the medial knee meniscus; the negative control group consisted of rabbits that received no implant. Macroscopic and histological evaluations of the neomeniscus were performed 12 and 24 weeks after implantation. The polymer scaffold implants adapted well to surrounding tissues, without apparent rejection, infection, or chronic inflammatory response. Fibrocartilaginous tissue with mature collagen fibers was observed predominantly in implants with seeded scaffolds compared to cell-free implants after 24 weeks. Similar results were not observed in the control group. Articular cartilage was preserved in the polymeric implants and showed higher chondrocyte cell number than the control group. These findings show that the PLDLA/PCL-T 90/10 scaffold has potential for orthopedic applications since this material allowed the formation of fibrocartilaginous tissue, a structure of crucial importance for repairing injuries to joints, including replacement of the meniscus and the protection of articular cartilage from degeneration. © 2013, Mary Ann Liebert, Inc. 2013. AD - Department of Materials Engineering, Faculty of Mechanical Engineering, University of Campinas (UNICAMP), Campinas, Brazil Laboratory of Biomaterials, Faculty of Medicine and Health Sciences, Pontifical Catholic University of Sao Paulo (PUC-SP), Joubert Wey, 290, Sorocaba, Sao Paulo 18030-070, Brazil Institute of Composite and Biomedical Materials, National Research Council of Italy, Naples, Italy AU - Esposito, A. R. AU - Moda, M. AU - Cattani, S. M. D. M. AU - De Santana, G. M. AU - Barbieri, J. A. AU - Munhoz, M. M. AU - Cardoso, T. P. AU - Barbo, M. L. P. AU - Russo, T. AU - D'Amora, U. AU - Gloria, A. AU - Ambrosio, L. AU - Duek, E. A. D. R. DB - Scopus DO - 10.1089/biores.2012.0293 IS - 2 KW - fibrochondrocyte culture meniscus regeneration PLDLA/PCL-T scaffold M3 - Article N1 - Cited By :62 Export Date: 10 November 2020 PY - 2013 SP - 138-147 ST - PLDLA/PCL-T scaffold for meniscus tissue engineering T2 - BioResearch Open Access TI - PLDLA/PCL-T scaffold for meniscus tissue engineering UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84889656039&doi=10.1089%2fbiores.2012.0293&partnerID=40&md5=adb1881f116f42f7b77ff8445dcd5216 VL - 2 ID - 1325 ER - TY - JOUR AD - Rutgers University-New Jersey Medical School, Department of Neurosurgery, Newark, NJ, United States Yale University School of Medicine, Department of Neurosurgery, New Haven, CT, United States St. Luke's Roosevelt Hospital Center, Hyman Newman Institute of Neurology and Neurosurgery New York, New York, United States Warren Alpert School of Medical at Brown University, Rhode Island, United States Abbott Northwestern Hospital, Department of Interventional Neuroradiology, Minneapolis, MN, United States UCSF, Department of Neurology and Radiology, San Francisco, CA, United States Columbia Presbyterian Hospital, Department of Neurointerventional Surgery, New York, NY, United States University of Cincinnati, Department of Neurosurgery, Cincinnati, OH, United States Wexner Medical Center, Department of Neurosurgery, Columbus, OH, United States University of Chicago, Department of Radiology, Chicago, IL, United States Christiana Care Health Systems, Department of Neurointerventional Surgery, Newark, DE, United States Stanford University, Department of Neurosurgery and Radiology, Stanford, CA, United States Dartmouth-Hitchcock Medical Center, Department of Radiology, Neurology and Neurosurgery, Lebanon, NH, United States New York Presbyterian Hospital, Weill Cornell Medical College, Department of Neurological Surgery, New York, NY, United States WUCSF, Department of Radiology, San Francisco, CA, United States Cleveland Clinic, Cleveland Clinic Stroke Program, Cleveland Heights, OH, United States Northwestern University, Feinberg School of Medicine, Chicago, IL, United States Massachusetts General Hospital, NeuroEndovascular Program, Boston, MA, United States Royal University Hospital, University of Saskatchewan, Department of Neurosurgery, Saskatoon, SK, Canada Cleveland Clinic, Neurosurgery Department, Cleveland, OH, United States University of Southern California, Department of Neurosurgery, Los Angeles, CA, United States UT Southwestern, Department of Neuroradiology, Dallas, TX, United States Cedars-Sinai Medical Center, Department of Neurosurgery, Los Angeles, CA, United States AU - Gandhi, C. D. AU - Bulsara, K. R. AU - Fifi, J. AU - Kass-Hout, T. AU - Grant, R. A. AU - Almandoz, J. E. D. AU - English, J. AU - Meyers, P. M. AU - Abruzzo, T. AU - Prestigiacomo, C. J. AU - Powers, C. J. AU - Lee, S. K. AU - Albani, B. AU - Do, H. M. AU - Eskey, C. J. AU - Patsalides, A. AU - Hetts, S. AU - Hussain, M. S. AU - Ansari, S. A. AU - Hirsch, J. A. AU - Kelly, M. AU - Rasmussen, P. AU - Mack, W. AU - Pride, G. L. AU - Alexander, M. J. AU - Jayaraman, M. V. DB - Scopus DO - 10.1136/neurintsurg-2014-011357 IS - 8 M3 - Article N1 - Cited By :25 Export Date: 10 November 2020 PY - 2014 SP - 567-577 ST - Platelet function inhibitors and platelet function testing in neurointerventional procedures T2 - Journal of NeuroInterventional Surgery TI - Platelet function inhibitors and platelet function testing in neurointerventional procedures UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84906974198&doi=10.1136%2fneurintsurg-2014-011357&partnerID=40&md5=36ae1686de907538a2dd9849bdbaa813 VL - 6 ID - 1296 ER - TY - JOUR AB - Introduction: Plasminogen (PLG) deficiency is a rare inherited disorder that can involve multiple systems leading to deficient fibrinolysis and subsequent impairment of the wound healing capacity of mucus membranes. Type 1 hypoplasminogenemia, is defined by low plasminogen levels and normal or decreased PLG activity. Patients exhibit multi-organ ligneous inflammation with conjunctiva, gingival lesions or, less frequently, involving the tracheobronchial tree or hydrocephalus. Type 2 dysplasminogenemia, a polymorphic variant, presents with normal or slightly decreased PLG levels but significantly decreased activity and has no known reported clinical associations. Our report describes a two year old male with clinical, serologic, and genetic findings of PLG deficiency with tracheobronchial involvement. Case description: A 2 year old male was admitted with persistent cough, wheezing, and hypoxia due to an adenovirus infection. He developed recurrent left lower lobe pneumonia partially responsive to IV antibiotics. Flexible bronchoscopy (FB) revealed raised lesions at the left lower lobe bronchus which resolved spontaneously, but recurred at the left main stem. Repeated bronchoalveolar lavages (BAL) grew multiple organisms including S. viridans, M catarrhalis, H influenzae, S pneumoniae, and Staph. aureous; foreign bodies were not seen. Past medical history was significant for urosepsis, GERD at infancy, failure to thrive, myringotomy complicated by granuloma formation. Subsequently, the child developed a right lower lid conjunctival lesion which recurred after multiple attempts at manual and surgical removal but resolved after Restasis therapy. Immune workup, including vaccination antibody response, immunoglobulin levels, CD4 and CD8 counts, and sweat chloride, were normal. Lymphocyte mitogen screen showed a decreased response to candida in an otherwise normal screen despite prior episodes of thrush. Chest Ct persistently showed LLL bronchiectasis with unresolved infiltrates. Pneumonias did not resolve fully with prolonged antibiotics, nebulized bronchodilators, steroids, DNAse dornase, and vest therapy. Due to history of recurrent pneumonias, tympanic membrane granulomas and conjunctival findings, the child was tested for plasminogen deficiency. He had normal levels of plasminogen with a markedly decreased level of plasminogen activity and antigen. DNA testing revealed the most common missense mutation Lys19>Glu (K19E) in a homozygous manner. Furthermore, several known homozygous PLG gene polymorphisms were identified. Discussion: Plasminogen deficiency must be considered in children with ligneous inflammation of the upper and lower respiratory tract, especially if associated with conjunctiva, or gingival involvement. There is a need for more research understanding this condition, where incidence may be underestimated, particularly looking for therapeutic options when the tracheobronchial system is involved. AD - T.B. Sotomayor, West Virginia University, Morgantown, WV, United States AU - Sotomayor, T. B. AU - Shin, E. AU - Ziss, B. AU - Carpio, K. DB - Embase IS - 1 KW - plasminogen antibiotic agent deoxyribonuclease CD4 antigen antigen steroid cyclosporine mitogenic agent chloride CD8 antigen DNA society human pneumonia child conjunctiva tracheobronchial tree granuloma inflammation male therapy immunoglobulin blood level adenovirus infection wound healing hypoxia book vaccination antibody response myringotomy wheezing patient fibrinolysis mucosa coughing urosepsis infancy hydrocephalus medical history foreign body lymphocyte lung lavage bronchus bronchoscopy sweat Candida thorax bronchiectasis eardrum diseases missense mutation DNA polymorphism lower respiratory tract failure to thrive LA - English M3 - Conference Abstract N1 - L70840780 2012-08-27 PY - 2010 SN - 1073-449X ST - Plasminogen deficiency with tracheobronchial involvement T2 - American Journal of Respiratory and Critical Care Medicine TI - Plasminogen deficiency with tracheobronchial involvement UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70840780&from=export http://ajrccm.atsjournals.org/cgi/reprint/181/1_MeetingAbstracts/A3327?sid=46c26b6b-7eee-4d32-b8c0-1703a84064a7 VL - 181 ID - 566 ER - TY - JOUR AB - Objectives: To investigate the diagnostic value of contrast-enhanced computed tomography (CT) for the prediction of deep neck abscesses in different deep neck spaces and to evaluate the false-positive results. Method: We retrospectively analysed the clinical charts, CT examinations, surgical findings, bacteriology, pathological examinations and complications of hospitalised patients with a diagnosis of deep neck abscess from 2004 to 2010. The positive predictive values (PPV) for the prediction of abscesses by CT scan in different deep neck spaces were calculated individually on the basis of surgical findings. Results: A total of 162 patients were included in this study. All patients received both intravenous antibiotics and surgical drainage. The parapharyngeal space was the most commonly involved space. The overall PPV for the prediction of deep neck abscess with contrast-enhanced CT was 79.6%. The PPV was 91.3% when more than one deep neck space was involved but only 50.0% in patients with isolated retropharyngeal abscesses. In the false-positive group, cellulitis was the most common final result, followed by cystic degeneration of cervical metastases. Five specimens taken intra-operatively revealed malignancy and four of these were not infected. Conclusions: There are some limitations affecting the differentiation of abscesses and cellulitis, particularly in the retropharyngeal space. A central necrotic cervical metastatic lymph node may sometimes also mimic a simple pyogenic deep neck abscess on both clinical pictures and CT images. Routine biopsy of the tissue must be performed during surgical drainage. AD - Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, Nanhsiao Street 135, 500 Changhua, Taiwan Department of Radiology, Changhua Christian Hospital, Changhua, Taiwan AU - Chuang, S. Y. AU - Lin, H. T. AU - Wen, Y. S. AU - Hsu, F. J. DB - Scopus IS - 1 KW - Computed tomography Deep neck abscess Diagnosis Head and neck cancer Pseudo-aneurysm M3 - Article N1 - Cited By :11 Export Date: 10 November 2020 PY - 2013 SP - 45-52 ST - Pitfalls of CT for deep neck abscess imaging assessment: A retrospective review of 162 cases T2 - B-ENT TI - Pitfalls of CT for deep neck abscess imaging assessment: A retrospective review of 162 cases UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879545333&partnerID=40&md5=06ba537a873afee896f45ea19deb8f89 VL - 9 ID - 1331 ER - TY - JOUR AB - Background Information: The purpose of this educational exhibit is to demonstrate the radiographic imaging characteristics of various orthopedic sponges to heighten awareness and aid in detection of foreign bodies in the intraoperative and perioperative setting. Educational Goals/Teaching Points: The educational exhibit will be organized using a pictorial approach to demonstrate the radiographic characteristics of various orthopedic sponges. Teaching points would include a literature review of the prevalence of retained operative foreign bodies as well as the sensitivity of conventional radiographs in detection. Key Anatomic/Physiologic Issues and Imaging Findings/Techniques: Various types of sponges, including lap sponges, peanut dissectors, etc., have been collected and conventional radiographs have been performed to document their appearance. The surgical sponges were imaged under wet and dry conditions both with and without a phantom to simulate the in vivo appearance of missing sponges. Comparison of radiographs with digital photographs was made. Conclusion: In various clinical settings, including emergent orthopedic trauma surgery, radiologists are often consulted to review intraoperative radiographs for sponge miscounts. It is essential for radiologists to be aware of the radiographic appearance of various orthopedic sponges to aid in accurate detection of potential foreign bodies. AD - R. Wu, Winthrop-University Hospital, Mineola, NY, United States AU - Wu, R. AU - Scalcione, L. AU - Kulesa, M. AU - Luchs, J. DB - Embase IS - 5 KW - surgical sponge society X ray X ray film foreign body imaging radiologist prevalence teaching peanut phantom photography traumatology LA - English M3 - Conference Abstract N1 - L70503466 2011-08-20 PY - 2011 SN - 0361-803X SP - A201 ST - A pictorial essay of orthopedic surgical sponges missing in action T2 - American Journal of Roentgenology TI - A pictorial essay of orthopedic surgical sponges missing in action UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70503466&from=export http://www.ajronline.org/cgi/content/full/196/5_Supplement/A201 VL - 196 ID - 543 ER - TY - JOUR AB - Case: An 85-year-old male patient presented with a history of loss of appetite and vague upper abdominal discomfort of 1 month duration. The vital signs were stable. The physical examination revealed mild epigastric tenderness. The liver enzymes, CEA, CA19-9, AFP and the complete blood counts were all normal. A contrast-enhanced CT scan of the abdomen revealed air and hyperdense tracking from the lefthepatic lobe adjacent to the stomach causing a concern for a fistula between the stomach and the liver possibly secondary to a gastric tumor. An upper GI endoscopy revealed a toothpick which had penetrated the gastric walls and bridging the greater and the lesser curve of the antrum with a minimally raised area around the points of penetration. The toothpick was removed with difficulty using a snare and mucosal biopsies were obtained from the raised area. An immediate surgical consultation was sought, however, no surgical intervention undertaken as the patient had no signs of acute abdomen. The patient was given antibiotics for 2 weeks. A follow-up CT scan of the abdomen 2 weeks later demonstrated an interval resolution of the previously noted gastro-hepatic fistula without any evidence of extravasation of the contrast confirming a complete healing of the fistulous tract. All gastric biopsies were negative for malignancy. Upon questioning, the patient admitted to chewing on a toothpick 3-4 weeks previously while watching an exciting football game and going to bed at night. Later he realized that the toothpick had disappeared from his mouth. Discussion: We presented an interesting patient who developed a gastro-hepatic fistula caused by a toothpick. Gastrohepatic fistula have been rarely reported following transarterial chemoembolizaton (A Jain, et al), radiofrequency ablation (SH Lee, et al) for hepatocellular cancer treatment and cholangiocarcinoma (Aung, et al). Our case is the first case of gastro-hepatic fistula from accidentally ingesting a foreign body. AD - A. Nabh, Gastroenterology and Hepatology, Georgia Health Sciences University, Augusta, GA, United States AU - Nabh, A. AU - Gangireddy, V. G. R. AU - Singh, E. AU - Spurr, C. AU - Sridhar, S. DB - Embase DO - 10.1038/ajg.2012.268 KW - antibiotic agent liver enzyme carcinoembryonic antigen college gastroenterology stomach patient human fistula abdomen computer assisted tomography appetite blood cell count endoscopy surgery stomach tumor mastication liver bile duct carcinoma stomach wall biopsy consultation acute abdomen follow up physical examination stomach biopsy healing extravasation abdominal discomfort football night radiofrequency ablation cancer therapy male foreign body vital sign LA - English M3 - Conference Abstract N1 - L70893758 2012-10-18 PY - 2012 SN - 0002-9270 SP - S58 ST - “picking” the problem of an upset stomach T2 - American Journal of Gastroenterology TI - “picking” the problem of an upset stomach UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70893758&from=export http://dx.doi.org/10.1038/ajg.2012.268 VL - 107 ID - 503 ER - TY - JOUR AB - Purpose: To assess the long-term effectiveness and safety of photorefractive intrastromal corneal crosslinking (CXL) in patients with low myopia. Setting: Ruhr University Eye Hospital, Bochum, Germany. Design: Prospective case series. Methods: Healthy eyes with myopia were treated with photorefractive intrastromal CXL using the Mosaic System. Riboflavin 0.1% solution (VibeX Rapid) was topically administered, followed by 365 nm ultraviolet-A (30 mW/cm2) irradiance. Efficacy was assessed by the uncorrected distance visual acuity (UDVA), manifest refraction spherical equivalent (MRSE), and keratometry. Safety was assessed by corrected distance visual acuity (CDVA), slitlamp biomicroscopy, endothelial cell count, and adverse event rates. Results: Fourteen patients (24 eyes) with a mean age of 35.7 years were included. At all follow-ups, a statistically significant improvement in UDVA was observed (all P <.001). The CDVA progressively improved from 1 month postoperatively and a statistically significant improvement was achieved at 12 months (P <.001). The average reduction in manifest sphere was 0.90 diopter (D) ± 0.40 (SD) by 12 months. There were no significant differences in mean manifest sphere and MRSE at 3, 6, or 12 months. Compared with baseline, significant reductions in corneal curvature were also observed at all follow-ups (all P <.05). There were no significant changes in endothelial cell density (P = 1.00) or number of cells (P =.95) at 12 months postoperatively, and no adverse events were reported. Conclusion: Photorefractive intrastromal CXL was a safe and efficacious treatment of refractive error in patients with low myopia. AD - M. Elling, Ruhr University Eye Hospital, In der Schornau 23-25, Bochum, Germany AU - Elling, M. AU - Kersten-Gomez, I. AU - Dick, H. B. C1 - vibex rapid(Avedro) C2 - Avedro DB - Embase Medline DO - 10.1016/j.jcrs.2018.01.022 IS - 4 KW - riboflavin vibex rapid adult adverse outcome article cell density clinical article cornea curvature cornea surgery corrected distance visual acuity dry eye endothelium cell follow up foreign body Germany human keratometry light irradiance low myopia manifest refraction spherical equivalent myopia photorefractive intrastromal corneal crosslinking postoperative complication priority journal prospective study slit lamp microscopy ultraviolet A radiation uncorrected distance visual acuity university hospital visual acuity visual system parameters LA - English M3 - Article N1 - L2000755425 2018-05-21 2018-05-23 PY - 2018 SN - 1873-4502 0886-3350 SP - 487-495 ST - Photorefractive intrastromal corneal crosslinking for treatment of myopic refractive error: Findings from 12-month prospective study using an epithelium-off protocol T2 - Journal of Cataract and Refractive Surgery TI - Photorefractive intrastromal corneal crosslinking for treatment of myopic refractive error: Findings from 12-month prospective study using an epithelium-off protocol UR - https://www.embase.com/search/results?subaction=viewrecord&id=L2000755425&from=export http://dx.doi.org/10.1016/j.jcrs.2018.01.022 VL - 44 ID - 349 ER - TY - JOUR AB - BACKGROUND: Phosphoglyceride crystal deposition disease (PGDD) is characterized by phosphoglyceride crystal deposition that simulates neoplasia in soft tissue scars or bone. Reports of PGDDs are rare. Here, we present the case of a patient with PGDD in the abdominal wall. CASE PRESENTATION: A 57-year-old Japanese man with worsening right lower abdominal pain had no significant family or occupational history. Laboratory data showed elevated inflammatory markers with a white blood cell count of 14,400 × 10(9)/L and C-reactive protein of 11.8 mg/L, but no other abnormalities. Helical computed tomography (CT) revealed a tumor in the abdominal wall (longest dimension, approximately 10 cm). Positron emission tomography-CT revealed fluorodeoxyglucose accumulation in the mass only (SUVmax, 41). Clinical and radiographic findings suggested malignant lymphoma, undifferentiated sarcoma, or liposarcoma. He underwent exploratory laparotomy and further treatment. At surgery, we found a huge milky-whitish mass with a rough surface in the transversus abdominis. Complete resection was performed and his postoperative recovery was good. Surprisingly, the final pathologic diagnosis was phosphoglyceride crystal deposition disease with the characteristic crystal deposition in a corolla shape, histiocytic reaction with abundant foreign-body-type giant cells, and no evidence of neoplasia. The patient remains asymptomatic with no disease recurrence. CONCLUSION: Although phosphoglyceride crystal deposition disease in the abdominal wall is rarely encountered in clinical practice, its inclusion in differential diagnosis is important. Given the occurrence at sites of invasive procedures, we believe efforts to reduce invasiveness when performing surgery and follow-up for early detection of recurrence are important. AD - Department of Surgery, Taragi Municipal Hospital, 4210 Taragi, Taragi-machi, Kuma-gun, Kumamoto, 868-0598, Japan. o-naka@live.jp. Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto City, Kumamoto, 860-8556, Japan. AN - 30232573 AU - Nakahara, O. AU - Baba, H. C2 - PMC6146114 DA - Sep 19 DO - 10.1186/s40792-018-0516-2 DP - NLM ET - 2018/09/21 IS - 1 KW - Foreign-body granuloma Phosphoglyceride crystal deposition disease Soft tissue tumor with the principles of the Declaration of Helsinki. CONSENT FOR PUBLICATION: Written informed consent was obtained from the patient for publication of this case report and any accompanying images. COMPETING INTERESTS: The authors declare that they have no competing interest. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. LA - eng N1 - 2198-7793 Nakahara, Osamu Baba, Hideo Journal Article Surg Case Rep. 2018 Sep 19;4(1):120. doi: 10.1186/s40792-018-0516-2. PY - 2018 SN - 2198-7793 (Print) 2198-7793 SP - 120 ST - Phosphoglyceride crystal deposition disease in the abdominal wall: a case report T2 - Surg Case Rep TI - Phosphoglyceride crystal deposition disease in the abdominal wall: a case report VL - 4 ID - 221 ER - TY - JOUR AD - Aberdeen Royal Infirmary, Aberdeen AB25 2ZN, United Kingdom AU - Baker, J. AU - McClelland, D. AU - Dempsey, O. J. C7 - e2690 DB - Scopus DO - 10.1136/bmj.e2690 IS - 7861 M3 - Article N1 - Export Date: 10 November 2020 PY - 2012 ST - A persisting puzzling pneumonia in a young man T2 - BMJ (Online) TI - A persisting puzzling pneumonia in a young man UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84862504238&doi=10.1136%2fbmj.e2690&partnerID=40&md5=a1ebf5ea368988ff4fcf16626346b35b VL - 344 ID - 1367 ER - TY - JOUR AB - Introduction: Cases of a foreign body ingestion often require surgical treatment due to perforation or penetration. There is a possibility that plastic bread bag clips also cause serious adverse events when they are ingested. Presentation of a case: We report a rare case of peritonitis with small intestinal perforation caused by a plastic bread bag clip that needed surgical treatment. A 47-year-old man was taken to our hospital because of abdominal distension and vomiting. A computed tomography test demonstrated findings of small intestinal perforation, and a high-density object was seen in the jejunum. During emergency surgery, it was discovered that a plastic bread bag clip had caused the perforation. Discussion: Some cases of gastrointestinal tract perforation or bleeding due to the ingestion of bread bag clips have been reported overseas. Because bread bag clips are normally radiolucent, they are impossible to discover when accidentally ingested, so diagnosis is difficult unless the patient remembers the incident. The shape of plastic bread bag clips is unique and can result in a trap-like effect, which prevents easy removal once ingested. Conclusion: Bread bag clips need caution in handling, and in cases of accidental ingestion, careful observations should be made to allow for removal within reach of upper GI endoscopy. The following case report has been reported in line with the SCARE criteria [1]. © 2018 The Authors AD - Department of Surgery, Okayama Saiseikai General Hospital, 2-25 Kokutaicho, kita-ku, Okayama, 7008511, Japan Department of Surgery, Okayama Saiseikai General Hospital, Japan AU - Mitsui, E. AU - Inaba, M. AU - Mimura, T. DB - Scopus DO - 10.1016/j.ijscr.2018.08.016 KW - Bread bag clip Foreign body Small intestinal perforation M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2018 SP - 130-133 ST - Peritonitis with small intestinal perforation caused by a plastic bread bag clip: A case report T2 - International Journal of Surgery Case Reports TI - Peritonitis with small intestinal perforation caused by a plastic bread bag clip: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85052228640&doi=10.1016%2fj.ijscr.2018.08.016&partnerID=40&md5=1cb4bc0923cc61835f7c50ad89ad49d8 VL - 51 ID - 1101 ER - TY - JOUR AB - Mycobacterium fortuitum is a rapid growing nontuberculous organism that has rarely been associated with peritonitis in an otherwise healthy host. We describe a patient who developed peritonitis due to the organism after gastric banding operation, which resolved after removal of the gastric band and institution of appropriate antibiotic therapy. AD - Department of Medicine, King Khalid University Hospital, College of Medicine, Riyadh, Saudi Arabia AU - Al Majid, F. M. DB - Scopus DO - 10.4103/1319-3767.61239 IS - 2 KW - Hospital acquired Mycobacterium fortuitum Peritonitis M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2010 SP - 113-115 ST - Peritonitis due to Mycobacterium fortuitum following gastric banding T2 - Saudi Journal of Gastroenterology TI - Peritonitis due to Mycobacterium fortuitum following gastric banding UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77950526508&doi=10.4103%2f1319-3767.61239&partnerID=40&md5=d1c421c1a737e1dcd367e04b3f3604a0 VL - 16 ID - 1463 ER - TY - JOUR AB - Catheters are implanted into the peritoneal cavity during the process of peritoneal dialysis. Though these catheters may be effective and beneficial, the impact of catheters on the immune system is poorly understood. Catheters and other devices implanted in the peritoneal cavity elicit a foreign body reaction. However, the immunological consequences of this remain uncharacterized. To model this, catheters were implanted into the peritoneal cavity of healthy mice. Catheter implantation induced rapid cellular changes within the peritoneal cavity. Whereas B-cells and T-cells were reduced, catheter implantation was associated with the rapid expansion of F4/80-low-positive, CD11b-positive macrophages that elaborated IL-10, and suppressed T-cell division and Th1 skewing in co-culture assays. Peritoneal catheter elicited macrophages had increased Jmjd3 but reduced NF-κB activation, and their emergence was MyD88-dependent. Collectively, these studies indicate that foreign body implantation into the peritoneal cavity is associated with the expansion of suppressor macrophages. Whether peritoneal cavity catheter implantation may have systemic immunoregulatory roles remains to be explored. © 2012 Elsevier Inc. AD - Department of Internal Medicine, University of Texas Southwestern Medical School, Dallas, TX 75390, United States Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea College of Medicine, Seoul, South Korea AU - Min, S. Y. AU - Fu, Y. AU - Hutcheson, J. AU - Wu, T. AU - Khobahy, E. AU - Zhu, J. AU - Vanarsa, K. AU - Du, Y. AU - Park, M. J. AU - Park, H. S. AU - Saxena, R. AU - Kim, H. Y. AU - Mohan, C. DB - Scopus DO - 10.1016/j.clim.2012.01.003 IS - 1 KW - Foreign body reaction IL-10 Immune regulation Macrophages Peritoneal dialysis M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2012 SP - 59-72 ST - Peritoneal catheter implantation elicits IL-10-producing immune-suppressor macrophages through a MyD88-dependent pathway T2 - Clinical Immunology TI - Peritoneal catheter implantation elicits IL-10-producing immune-suppressor macrophages through a MyD88-dependent pathway UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84862828366&doi=10.1016%2fj.clim.2012.01.003&partnerID=40&md5=47068942d0f066311cdfa7d38bd85ac4 VL - 143 ID - 1373 ER - TY - JOUR AB - Periprosthetic joint infection (PJI) remains a serious complication following a total joint replacement. Diagnosis and management of PJI is challenging for surgeons since there is no “gold standard”. This challenging condition requires a coordinated management approach to achieve good patient outcomes. Further difficulties involve choosing the optimal method to treat the periprosthetic joint infection. In this article, it is stressed the role of the two-stage revision: implant removal, debridement and placement of an antibiotic spacer, and antibiotic therapy with cessation prior to reimplantation. Published literature shows that two stage revision is a valid treatment option for periprosthetic joint infection. (www.actabiomedica.it) © Mattioli 1885. AD - Istituto Clinico Humanitas, Rozzano, MI, Italy Istituto Ortopedico Rizzoli, Bologna, Italy Istituto Clinico Humanitas, Humanitas University, Rozzano, MI, Italy AU - Bonanzinga, T. AU - Tanzi, P. AU - Iacono, F. AU - Ferrari, M. C. AU - Marcacci, M. DB - Scopus DO - 10.23750/abm.v88i4-S.6802 KW - Infection Knee Periprosthetic joint infection Revision Two stage M3 - Article N1 - Export Date: 10 November 2020 PY - 2017 SP - 114-119 ST - Periprosthetic knee infection: Two stage revision surgery T2 - Acta Biomedica TI - Periprosthetic knee infection: Two stage revision surgery UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85037651985&doi=10.23750%2fabm.v88i4-S.6802&partnerID=40&md5=74d39f389c2f308a71ebe139a7b0b5a4 VL - 88 ID - 1120 ER - TY - JOUR AB - Objective: Transcatheter closure of ASD become feasible and safe alter native to surgical closure. Although excellent results have been reported for transcatheter occlusion with devices, concerns have arises about peri-interventional complications. Despite implanting an intracardiac, potentially thrombogenic foreign body, reports on thromboembolic complications related to an interatrial device are rare. This case report illustrates that periprocedural thrombus formation occur at transport catheter. Methods: A 45 years old man presented emergency service with cerebrovascular accident. He had no past medical history except smoking (30 pocket/year). During his evaluation at emergency service, complete blood count, biochemical tests including renal-liver function tests and thyroid function tests, thrombophilia panel parameters (prothrombin time, activated partial thromboplastin time, international normalized ratio, protein C activity, protein S (total and free), antithrombin III, anticardiolipin antibodies, homocysteine, factor V Leiden mutation, and prothrombin gene PCR) were in normal limits. The ECG was in sinus rhytm, incomplete RBBB and telecardiogram was normal. Imaging with cranial MR and MRA revealed milimetric acute ischemic lesions in left precentral gyrus, superior temporal and frontal areas. Transcranial doppler ultrasound showed right to left shunt like waterspout pattern. So PFO or ASD were suspected in differential diagnosis. Interatrial septal aneurysm was detected with TTE. TEE revealed ASD with 10mm diameter in bicaval position, was relevant for percutaneous closure. There was no any other pathology. Patient was taken for transcatheter closure of ASD with TEE control under general anesthesia. Amplatzer® Septal Occluder device in 13mm diameter prepared for closure. After passing through the left atrium, there was thrombus formation at the tip of transport catheter of device. The occluder device deployed under TEE imaging and thrombus was taken in between arms of the device. The patient was anticoagulated with UFH infusion immediately during procedure. Results: Control TEE after implantation of device revealed no thrombus around occluder device. Patient was asypmtomatic after procedure with no neurological signs. Patient was discharged with oral anticoagulation. Control TTE before discharging showed that the device was positioned flat against the septum and appeared to be in complete contact with the septum. Patient was asymptomatic at 4th week control with normal TTE. Conclusions: Although percutaneous ASD closure is associated with low complication rate, it is not risk free. Patients shoul be followed closely and over a long term after closure. It is essential that the cardiology community should be aware of these rare complications. AD - U. Canpolat, Department of Cardiology, Hacettepe University, Ankara, Turkey AU - Canpolat, U. AU - Yorgun, H. AU - Ates, A. H. AU - Ulgen, A. AU - Kaya, E. B. AU - Okutucu, S. AU - Aytemir, K. AU - Oto, A. DB - Embase DO - 10.1016/S0167-5273(10)70301-6 KW - homocysteine blood clotting factor 5 Leiden prothrombin protein C protein S antithrombin III cardiolipin antibody heart atrium septum defect cardiovascular surgery cardiology society devices patient blood clotting emergency health service catheter imaging thrombus mutation nuclear magnetic resonance Doppler ultrasonography Doppler flowmetry heart right left shunt differential diagnosis gene pathology general anesthesia heart left atrium arm implantation neurologic disease anticoagulation aneurysm community occlusion intracardiac drug administration foreign body thromboembolism case report male infusion medical history smoking risk electrocardiogram heart right bundle branch block liver function test thyroid function test thrombophilia blood cell count prothrombin time partial thromboplastin time international normalized ratio cerebrovascular accident LA - English M3 - Conference Abstract N1 - L70138534 2010-06-10 PY - 2010 SN - 0167-5273 SP - S84-S85 ST - Periprocedural trombus formation during transcatheter closure of atrial septal defect with amplatzer® septal occluder T2 - International Journal of Cardiology TI - Periprocedural trombus formation during transcatheter closure of atrial septal defect with amplatzer® septal occluder UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70138534&from=export http://dx.doi.org/10.1016/S0167-5273(10)70301-6 VL - 140 ID - 569 ER - TY - JOUR AB - This study was undertaken to identify specific events that affected patient safety in perioperative service areas during a three-year period. The three most common types o reported incidents were incorrect counts, equipment malfunction, and medication errors. Data revealed significant disparities between health care facilities regarding what types of incidents were reported. Standardized language and rporting mechanisms would aid in the consistency and validity of current incident reporting and could help to improve perioperative patient safety. AD - University of Wisconsin, Oshkosh, USA. AN - 16674029 AU - Chappy, S. DA - Apr DO - 10.1016/s0001-2092(06)60008-2 DP - NLM ET - 2006/05/06 IS - 4 KW - Equipment Failure Foreign Bodies Humans Medical Errors/prevention & control/statistics & numerical data Midwestern United States Safety Management/*statistics & numerical data Surgical Equipment Surgical Procedures, Operative/*standards LA - eng N1 - Chappy, Sharon Journal Article Multicenter Study Research Support, Non-U.S. Gov't United States AORN J. 2006 Apr;83(4):871-4, 877-88, 891-7. doi: 10.1016/s0001-2092(06)60008-2. PY - 2006 SN - 0001-2092 (Print) 0001-2092 SP - 871-4, 877-88, 891-7 ST - Perioperative patient safety: a multisite qualitative analysis T2 - Aorn j TI - Perioperative patient safety: a multisite qualitative analysis VL - 83 ID - 59 ER - TY - JOUR AB - It is estimated that a quarter of patients with HIV/AIDS undergo at least one surgical procedure in their life time. Surgical outcomes in these patients from developing countries are poorly characterized and surgeons are often concerned about poor surgical outcomes, especially when their CD4 cell counts are less than 200 cells/µl. This study evaluated the surgical outcomes of HIV-infected patients undergoing various surgical procedures over a six-year period in a large tertiary care hospital from South India. Two hundred and ninety-three patients underwent 374 surgical procedures during the study period. The median duration of HIV prior to surgery was 1.9 years (range 0–18.8 years). Two-thirds (58%) were on highly active antiretroviral therapy (HAART) at the time of surgery with the median duration of this treatment being 38 months (n = 194). About one-third (35%) of surgical procedures were performed as an emergency. Abdomino-pelvic surgeries were the most common (225, 60%). Adverse surgical outcome defined as death or post-operative infection was seen in 25 (6.6%). The post-operative infection rate was 5% (20/374). The most common of these was surgical site infection observed in nine (60%) followed by pneumonia in five patients (33%) and urinary tract infection in one patient. Day 30 mortality was 2% (n = 8) and a quarter of these were reported to be related to post-operative infectious complications. On multivariate analysis, only preoperative haemoglobin of less than 10 g/dl was significantly associated with a poor surgical outcome. HIV-related parameters such as CD4 cell counts, duration of HIV infection and HAART regimen did not seem to contribute towards an adverse surgical outcome. AD - P. Rupali, Department of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, India AU - Shanthamurthy, D. AU - Manesh, A. AU - Zacchaeus, N. G. P. AU - Roy, L. R. AU - Rupali, P. DB - Embase Medline DO - 10.1177/0956462418764485 IS - 10 KW - prosthesis albumin antifungal agent efavirenz hemoglobin lamivudine lamivudine plus nevirapine plus zidovudine tenofovir abdominal surgery adolescent adult adverse outcome antifungal therapy article blood vessel graft CD4 lymphocyte count clinical outcome combination drug therapy controlled study debridement disease duration drug use elective surgery emergency surgery female follow up foreign body general anesthesia highly active antiretroviral therapy hospital discharge human Human immunodeficiency virus infected patient Human immunodeficiency virus infection India infant major clinical study male newborn open surgery pelvis surgery perioperative period pneumonia priority journal retrospective study side effect surgical infection surgical mortality tertiary care center treatment duration urinary tract infection virus load LA - English M3 - Article N1 - L624001036 2018-09-26 2018-10-02 PY - 2018 SN - 1758-1052 0956-4624 SP - 968-973 ST - Perioperative outcomes in human immunodeficiency virus-infected patients – the PRO HIV study T2 - International Journal of STD and AIDS TI - Perioperative outcomes in human immunodeficiency virus-infected patients – the PRO HIV study UR - https://www.embase.com/search/results?subaction=viewrecord&id=L624001036&from=export http://dx.doi.org/10.1177/0956462418764485 VL - 29 ID - 335 ER - TY - JOUR AB - INTRODUCTION: The association of Streptococcus milleri group with pyogenic liver abscess is well recognized. Streptococcus gordonii, however, is a bacterium not of the milleri group and is included among the colonizers of the periodontal environment as it has a high affinity for molecules in the salivary pellicle on tooth surfaces. Here, we describe a case where Streptococcus gordonii was isolated from a pyogenic liver abscess in a retired dentist with hepatic metastasis of colon carcinoma. The clinical features, work up, management, and significance are described. CASE DESCRIPTION/METHODS: An 85-year-old male with colon carcinoma status post hemicolectomy complicated by metastasis to the liver status post chemotherapy and resection presented to the ED with intermittent abdominal discomfort for 2 weeks. Laboratory values were significant for WBC count of 16,000 with a predominance of granulocytes at 85%. CT of the abdomen and pelvis demonstrated a large, 7.6 cm by 5.3 cm, collection in the liver, likely an abscess. Infectious Diseases was consulted and recommended initiation of Meropenem and Daptomycin, in addition to drainage of the collection. The suspected abscess was drained by IR and Streptococcus gordonii sensitive to Linezolid was isolated on bacterial culture. The patient was transitioned to IV Linezolid and Metronidazole given susceptibilities. The patient's WBC count then began trending upwards. CT of the chest exhibited a 1.2 cm by 0.7 cm loculated pleural effusion on the right side. The pleural fluid collection was drained and a chest tube was placed. Studies of the drainage revealed an exudative process, although gram stain and culture were negative. Repeat CT imaging one week later revealed reduction in the size of the liver abscess. The WBC count normalized to less than 10,000 and the patient was discharged with a two-week course of oral Linezolid and Metronidazole with close outpatient follow-up with Infectious Diseases and Oncology. DISCUSSION: Pyogenic liver abscesses are generally associated with enteric gram-negative bacilli, Streptococcus milleri group, Streptococcus pyogenes, and Staphylococcus aureus. Hepatic abscesses secondary to periodontal flora have not been demonstrated in the literature without direct trauma to the GI tract involving foreign bodies contaminated with these organisms. We propose a possible hematogenous route of infection likely associated with possible risk factors related to the patient's occupation as a dentist and history of dental manipulation. AD - T. Chokshi, SUNY Downstate Medical Center, Brooklyn, NY, United States AU - Chokshi, T. AU - Botti, E. AU - Arroyo-Mercado, F. AU - Likhtshteyn, M. AU - Hossain, N. AU - Doan Huynh, C. AU - Tello, D. AU - McFarlane, I. M. DB - Embase DO - 10.14309/01.ajg.0000598900.62221.e4 KW - daptomycin linezolid meropenem metronidazole abdomen abdominal discomfort aged bacterium culture cancer patient cancer surgery case report chest tube clinical article clinical feature colon carcinoma communicable disease complication conference abstract dentist drug combination drug therapy flora follow up foreign body gastrointestinal tract Gram staining granulocyte hemicolectomy hospital discharge human human cell leukocyte count liver metastasis male nonhuman occupation outpatient pelvis periodontium pleura effusion pleura fluid pyogenic liver abscess risk factor Staphylococcus aureus Streptococcus gordonii Streptococcus milleri very elderly LA - English M3 - Conference Abstract N1 - L630841007 2020-02-12 PY - 2019 SN - 1572-0241 SP - S1306 ST - Periodontal flora isolated from pyogenic liver abscess in a retired dentist with hepatic metastasis of colon carcinoma T2 - American Journal of Gastroenterology TI - Periodontal flora isolated from pyogenic liver abscess in a retired dentist with hepatic metastasis of colon carcinoma UR - https://www.embase.com/search/results?subaction=viewrecord&id=L630841007&from=export http://dx.doi.org/10.14309/01.ajg.0000598900.62221.e4 VL - 114 ID - 305 ER - TY - JOUR AB - Introduction and Objectives: Penile enhancement with injectable agents is a rising trend and yet has received little scientific attention, despite the possibility of serious complications. We report a case of delayed severe infection following penile filler insertion, leading to multi-organ failure and intensive care support. Methods: A 31-year-old man presented two days after unprotected sexual intercourse with progressive pain and swelling of the penile shaft. He had self-administered 50 mg of Prednisone for the swelling. Two months prior, the patient received subcutaneous hyaluronic filler injections at a cosmetic clinic for penile enlargement. Relevant past medical history included tubularised hypospadias repair and genital herpes simplex. The patient had multiple risk factors for deterioration including regular testosterone injections, multiple sexual partners, cocaine use, alcohol consumption of 22 standard drinks a day and a 10 pack-year smoking history. The patient was tachycardic to 127, hypotensive at 90/50 and febrile to 40”. Physical examination revealed gross penile oedema and erythema, with a ventral curvature of his entire shaft stopping at the base of the penis. There was a small abrasion on the ventral aspect 1 cm proximal to glans. Results: Overnight the patient developed septic shock with anuria and hypotension, requiring transfer to the intensive care unit for vasopressor and inotropic support. Repeat examination showed blistering of the penis over filler injection sites. His white cell count was 25, creatinine 391 and lactate 2.3. Antibiotics for necrotising fasciitis was commenced upon infectious disease advice. Penile exploration revealed multiple fluid-filled fillers which appeared pus stained. Fillers were drained and fluid sent for culture. There was no abscess or evidence of necrotising fasciitis intraoperatively and on imaging. Operative wound cultures grew streptococcus pyogenes (penicillin sensitive). He improved with intravenous antibiotics and was stepped down from intensive care after 4 days and discharged on day 8. The patient received 3 weeks of antibiotics, prophylactic valaciclovir and drug and alcohol review. One month post admission there was significant superficial skin loss to both ventral and lateral aspect of the penis, corresponding to the location of blistering, with healthy granulation tissue at the base. He was reviewed by the plastic surgeons for a split skin graft but opted for conservative management with regular dressings. Three months post presentation he reports normal sexual and urinary function. Conclusions: This is the first published case of a penile filler infection causing fulminant infection with multi-organ failure. The severity of the case is due to a combination of behavioural risk factors, presence of foreign material and previous penile surgery. The case highlights the importance of evaluating social risk-factors and need for further research into penile augmentation procedures. AD - N.W.M. Khor, Murnaghan Urology Department, Prince of Wales Hospital, Sydney, Australia AU - Khor, N. W. M. AU - Dhar, A. AU - Cameron-Strange, A. DB - Embase KW - alcohol antihypertensive agent cocaine creatinine filler hypertensive factor lactic acid penicillin derivative prednisone testosterone valaciclovir abrasion abscess adult alcohol consumption anuria bacterium culture blister communicable disease conference abstract conservative treatment deterioration drug combination drug therapy edema erythema foreign body genital herpes granulation tissue human human cell hypospadias hypotension in vitro study injection site inotropism intensive care unit leukocyte count male medical history multiple organ failure necrotizing fasciitis nonhuman pain penis physical examination plastic surgeon pus risk factor septic shock sexual function sexual intercourse skin defect smoking split thickness skin graft Streptococcus pyogenes tachycardia LA - English M3 - Conference Abstract N1 - L631581856 2020-04-30 PY - 2020 SN - 1464-410X SP - 13 ST - The perils of penile enlargement-a case of fulminant penile infection T2 - BJU International TI - The perils of penile enlargement-a case of fulminant penile infection UR - https://www.embase.com/search/results?subaction=viewrecord&id=L631581856&from=export VL - 125 ID - 286 ER - TY - JOUR AB - An adult Jack Russel terrier dog presented for evaluation of large-volume peritoneal and pleural effusion. Echocardiography revealed scant pericardial effusion and abnormally thickened pericardium. Electrocardiography revealed complete atrioventricular block with junctional and ventricular escape beats and occasional ventricular premature complexes. Computed tomography of the thorax confirmed diffuse abnormal thickening of the pericardium, and a tentative diagnosis of constrictive-effusive pericarditis was made. The dog underwent subtotal pericardiectomy to remove the parietal pericardium and permanent epicardial pacemaker implantation to manage bradycardia. Based on pericardial histopathology and immunohistochemistry, a diagnosis of pericardial hemangiosarcoma was made. Systemic chemotherapy was initiated with doxorubicin 1 month after surgery. Despite initial improvement with chemotherapy, the dog was euthanized 4 months after surgery because of development of recurrent pleural effusion. To the author's knowledge, this is the first case report in dogs to describe isolated pericardial location of hemangiosarcoma resulting in constrictive-effusive pericarditis. © 2019 Elsevier B.V. AD - College of Veterinary Medicine, Small Animal Clinical Sciences, Michigan State University, 736 Wilson Road, East Lansing, MI 48824, United States College of Veterinary Medicine, Veterinary Diagnostic Laboratory, Michigan State University, 4125 Beaumont Rd, Lansing, MI 48910, United States AU - Gunasekaran, T. AU - Olivier, N. B. AU - Smedley, R. C. AU - Sanders, R. A. DB - Scopus DO - 10.1016/j.jvc.2019.01.008 KW - Constrictive-effusive Pericardiectomy Pericarditis M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 81-87 ST - Pericardial Effusion in a Dog with Pericardial Hemangiosarcoma T2 - Journal of Veterinary Cardiology TI - Pericardial Effusion in a Dog with Pericardial Hemangiosarcoma UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85062239022&doi=10.1016%2fj.jvc.2019.01.008&partnerID=40&md5=2d883f9e7a342c51c40f61dad4983f9c VL - 23 ID - 1010 ER - TY - JOUR AB - A series of 48 patients with oesophageal perforations was reviewed retrospectively. Eighty-seven per cent of the perforations were iatrogenic. Twenty-four patients were treated conservatively; 3 of this group died. The other 24 patients were treated surgically and 4 of them died. Patients with alarming symptoms and/or a large perforation underwent operative treatment unless there were contra-indications. Retained foreign bodies after perforation, and malignancy in the perforation area, were considered as indications for operation. Conservative treatment was reserved for patients with minor tears combined with a less turbulent course. The interval between perforation and therapy was not of decisive importance for the mortality in our series. The clinical picture, which was dominated by chest pain, gave the earliest indication of perforation, while the responses of the sedimentation rate, temperature and white blood count occurred later and were less reliable diagnostic signs. AN - 6417971 AU - Erwall, C. AU - Ejerblad, S. AU - Lindholm, C. E. AU - Aberg, T. DA - Jan-Feb DO - 10.3109/00016488409130979 DP - NLM ET - 1984/01/01 IS - 1-2 KW - Adolescent Adult Aged Anti-Bacterial Agents/therapeutic use Child Child, Preschool Drainage Esophageal Perforation/etiology/pathology/surgery/*therapy Female Humans Infant Male Middle Aged Parenteral Nutrition Retrospective Studies Time Factors LA - eng N1 - Erwall, C Ejerblad, S Lindholm, C E Aberg, T Comparative Study Journal Article England Acta Otolaryngol. 1984 Jan-Feb;97(1-2):185-92. doi: 10.3109/00016488409130979. PY - 1984 SN - 0001-6489 (Print) 0001-6489 SP - 185-92 ST - Perforation of the oesophagus. A comparison between surgical and conservative treatment T2 - Acta Otolaryngol TI - Perforation of the oesophagus. A comparison between surgical and conservative treatment VL - 97 ID - 8 ER - TY - JOUR AB - INTRODUCTION: Ingesting a foreign body (FB) is not an uncommon occurrence. Most pass through the gastrointestinal (GI) tract uneventfully, and perforation is rare. The aim of this study was to report our experience with ingested FB perforations of the GI tract treated surgically at our institution. METHODS: A total of 62 consecutive patients who underwent surgery for an ingested FB perforation of the GI tract between 1990 and 2005 were retrospectively reviewed. Three patients with no definite FB demonstrated intraoperatively were included. RESULTS: The patients had a median age of 58 years, and 37 (60%) were male. Of the 59 FBs recovered, 55 (93%) were toothpicks and dietary FBs such as fish bones or bone fragments. A definitive preoperative history of FB ingestion was obtained for only two patients, and 36 of 52 patients (69%) wore dentures. Altogether, 18 (29%) perforations occurred in the anus or distal rectum, and 44 perforations were intraabdominal, with the most common abdominal site being the distal ileum (39%). Patients with FB perforations in the stomach, duodenum, and large intestine were significantly more likely to be afebrile (P = 0.043), to have chronic symptoms (> 3 days) (P < 0.001), to have a normal total white blood cell count (P < 0.001), and to be asymptomatic or present with an abdominal mass or abscess (P < 0.001) compared to those with FB perforations in the jejunum and ileum. CONCLUSIONS: Ingested FB perforation in the adult population is most commonly secondary to unconscious accidental ingestion and is frequently caused by dietary FBs especially fish bones. A preoperative history of FB ingestion is thus rarely obtained, although wearing dentures is a common risk factor. FB perforations of the stomach, duodenum, and large intestine tend to present with a longer, more innocuous clinical picture than perforations in the jejunum or ileum. AD - Department of Surgery, Singapore General Hospital, Outram Road, 169608, Singapore. bsgkp@hotmail.com AN - 16479337 AU - Goh, B. K. AU - Chow, P. K. AU - Quah, H. M. AU - Ong, H. S. AU - Eu, K. W. AU - Ooi, L. L. AU - Wong, W. K. DA - Mar DO - 10.1007/s00268-005-0490-2 DP - NLM ET - 2006/02/16 IS - 3 KW - Adult Aged Aged, 80 and over Deglutition Female Foreign Bodies/*complications/*surgery Humans Intestinal Perforation/*etiology/*surgery Male Middle Aged Retrospective Studies Risk Factors Treatment Outcome LA - eng N1 - Goh, Brian K P Chow, Pierce K H Quah, Hak-Mien Ong, Hock-Soo Eu, Kong-Weng Ooi, London L P J Wong, Wai-Keong Journal Article United States World J Surg. 2006 Mar;30(3):372-7. doi: 10.1007/s00268-005-0490-2. PY - 2006 SN - 0364-2313 (Print) 0364-2313 SP - 372-7 ST - Perforation of the gastrointestinal tract secondary to ingestion of foreign bodies T2 - World J Surg TI - Perforation of the gastrointestinal tract secondary to ingestion of foreign bodies VL - 30 ID - 58 ER - TY - JOUR AB - Introduction: Ingestion of foreign bodies is a common problem, particularly among the elderly, pediatric, and psychiatric populations. Most of the foreign bodies pass spontaneously and uneventfully within a week. Perforation of the gallbladder by an ingested sewing needle is extremely rare, and a single case has been reported in the literature. Case Report: We report a rare case of 30-year-old woman who accidentally ingested a sewing needle, which silently perforated the stomach and migrated to the gallbladder. Conclusion: For foreign bodies in the stomach and duodenum, the general management is usually conservative. In situations such as those in our presented case, if there is a history of foreign body ingestion and failure of its progress as well as the presence of acute abdomen, there may be an indication for surgery. © 2017 by Emergency Physicians Association of Turkey. AD - Department of Emergency Medicine, Bakirköy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey Department of General Surgery, Kars State Hospital, Kars, Turkey Department of Anesthesia and Reanimation, Kars State Hospital, Kars, Turkey AU - Doğan, H. AU - çağlayan, K. AU - Işler, B. F. AU - Arslan, H. AU - Özüçelik, D. N. DB - Scopus DO - 10.5152/jemcr.2016.1158 IS - 1 KW - Foreign bodies Gallbladder Perforation Sewing needle M3 - Article N1 - Export Date: 10 November 2020 PY - 2017 SP - 7-9 ST - Perforation of the gallbladder due to a swallowed sewing needle: Case report T2 - Akademik Acil Tip Olgu Sunumlari Dergisi TI - Perforation of the gallbladder due to a swallowed sewing needle: Case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85043629618&doi=10.5152%2fjemcr.2016.1158&partnerID=40&md5=b16b4535fba69a5987b0799ce568cd08 VL - 8 ID - 1154 ER - TY - JOUR AB - Report on eight cases of perforation of the oesophagus. Contrary to the opinion regarding carcinoma as the most frequent cause (Holinger, McGibbon and Mather) six of these cases were due to foreign bodies, one to a caustic burn and one to syphilis, the last-named being an exceptional case. In two cases of injury due to foreign bodies (pieces of bone) conservative treatment without chemotherapeutical agents was successful, although there was roentgenographic and endoscopic proof of perforation. The author further agrees with Holinger that the mediastinum must be opened by operation and drained if there are signs of progressive infection. A rise in the leucocytic count of the blood to 18,000 or more is regarded as particularly valuable in providing an indication for this treatment, a view which is supported by the cases described. The perforation of the oesophagus caused by caustic burning and by syphilis led to the formation of broncho-oesophageal fistulae. Both these patients died, one through subsequent suicide and one from bilateral bronchopneumonia, whilst a third succumbed to a fulminating sepsis (Holinger's classification) in spite of posterior and anterior mediastinotomy. The latter case gives rise to the question whether external removal of the foreign body with simultaneous drainage of the mediastinum should not be employed. Perforation of the pleura and formation of empyema can necessitate major surgical procedures and cause illness over a period of years. The diagnostic importance of the displacement of the oesophagus and widening of the mediastinal shadow seen in the roentgenogram are mentioned. AD - C.W. Engler, Cleveland, OH, United States AU - Engler, C. W. DB - Embase Classic IS - 3 KW - caustic agent blood bone bronchopneumonia carcinoma caustic burn classification conservative treatment diagnosis empyema esophagus esophagus fistula esophagus perforation foreign body general aspects of disease infection injury devices mediastinum patient perforation pleura sepsis suicide surgical technique syphilis X ray picture LA - English M3 - Article N1 - L280411943 1946-12-01 PY - 1946 SN - 0003-4894 SP - 667-680 ST - Perforation of the esophagus not caused by instrumentation. Review of eight cases T2 - Annals of Otology, Rhinology and Laryngology TI - Perforation of the esophagus not caused by instrumentation. Review of eight cases UR - https://www.embase.com/search/results?subaction=viewrecord&id=L280411943&from=export VL - 55 ID - 699 ER - TY - JOUR AB - A 79-year-old woman was urgently referred to a district hospital with dull central chest pain after swallowing a fish bone. The bone was removed by esophagoscopy. Eleven days later she presented because of hematemesis. Computed tomography and aortic arch angiography confirmed a diagnosis of esophageal perforation leading to mediastinitis and the presence of an infected pseudoaneurysm. The infected pseudoaneurysm was completely resected, followed by direct aorto-aorta anastomosis and omental coverage in a one-stage operation. She improved and was discharged 2 months later. © 2008 The Japanese Association for Thoracic Surgery. AD - Division of Cardiovascular Surgery, National Hospital Organization Hokkaido Cancer Center, 4-2 Kikusui, Shiroishiku, Sapporo 003-0804, Japan AU - Kunishige, H. AU - Myojin, K. AU - Ishibashi, Y. AU - Ishii, K. AU - Kawasaki, M. AU - Oka, J. DB - Scopus DO - 10.1007/s11748-008-0266-3 IS - 8 KW - Esophageal perforation Fish bone Infected pseudoaneurysm Omental coverage M3 - Article N1 - Cited By :16 Export Date: 10 November 2020 PY - 2008 SP - 427-429 ST - Perforation of the esophagus by a fish bone leading to an infected pseudoaneurysm of the thoracic aorta T2 - General Thoracic and Cardiovascular Surgery TI - Perforation of the esophagus by a fish bone leading to an infected pseudoaneurysm of the thoracic aorta UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-49649086040&doi=10.1007%2fs11748-008-0266-3&partnerID=40&md5=6fc67d059d555452570437a918de309e VL - 56 ID - 1522 ER - TY - JOUR AB - Introduction. Meckel's diverticulum is the commonest congenital abnormality of the gastrointestinal tract. Most of them are asymptomatic but can rarely present with forms of complications such as bleeding, obstruction, diverticulitis, intussusception and neoplasm. Patients with a perforation of Meckel's diverticulum by a foreign body are rare and may present with right iliac fossa pain, which mimics acute appendicitis. Case presentation. A 64-year-old Greek man presented with an eight-hour history of right iliac fossa pain. On examination, our patient had tenderness in his right iliac fossa. A provisional diagnosis of acute appendicitis was made. He was taken to theatre with the option of an appendicectomy. His appendix was found to have an about normal appearance. An inflamed Meckel's diverticulum that had been perforated by a fish bone was found to be the cause of the abdominal pain. A Meckel's diverticulectomy was performed. Our patient made an uneventful recovery and was discharged after two days. Conclusions: Complications of Meckel's diverticulum can be difficult to diagnose and early recognition and timely operative intervention must occur in order to provide the best outcome for these patients. This is an interesting and unusual case of perforation of Meckel's diverticulum that highlights the importance of considering Meckel's diverticulum as a differential diagnosis in every patient presenting with acute abdomen. © 2013 Dimitriou et al.; licensee BioMed Central Ltd. AD - Department of General Surgery, General Hospital of Thessaloniki, O Agios Dimitrios Kanari 7 Stavroupoli, Thessaloniki PC56430, Greece AU - Dimitriou, I. AU - Evaggelou, N. AU - Tavaki, E. AU - Chatzitheoklytos, E. C7 - 231 DB - Scopus DO - 10.1186/1752-1947-7-231 KW - Acute appendicitis Meckel's diverticulum Perforation M3 - Article N1 - Cited By :9 Export Date: 10 November 2020 PY - 2013 ST - Perforation of Meckel's diverticulum by a fish bone presenting as acute appendicitis: A case report T2 - Journal of Medical Case Reports TI - Perforation of Meckel's diverticulum by a fish bone presenting as acute appendicitis: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84884743683&doi=10.1186%2f1752-1947-7-231&partnerID=40&md5=50fdbd67f47a513702a4277e76587e0b VL - 7 ID - 1306 ER - TY - JOUR AB - OBJECTIVE: To report the injury patterns associated with perforating (through-and-through) injuries of the globe and the visual impact of these injuries on patients with combat ocular trauma (COT) seen at Walter Reed Army Medical Center (WRAMC) from March 2003 through October 2006. DESIGN: Retrospective, noncomparative, interventional case series. PARTICIPANTS: Sixty-five eyes of 61 United States military soldiers deployed during Operation Iraqi Freedom sustaining perforating globe injuries and treated subsequently at WRAMC. INTERVENTION: Principal procedures included enucleation and 20-gauge 3-port pars plana vitrectomy with or without intraocular foreign body removal. MAIN OUTCOME MEASURES: Final visual acuity and rates of proliferative vitreoretinopathy, enucleation, and endophthalmitis. RESULTS: Average patient age was 29 years, with an average of 200 days of postinjury follow-up (median, 97 days; range, 4-1023 days). Nineteen patients confirmed the use of eye protection at the time of injury, whereas 25 patients did not use eye protection. The median presenting visual acuity at WRAMC was no light perception (range, no light perception to hand movements). Twenty-five patients underwent primary enucleation, 1 was eviscerated, and 12 patients underwent secondary enucleation within 2 weeks of surgery. Of 19 patients undergoing pars plana vitrectomy, median visual acuity at presentation was light perception and the median final visual acuity was counting fingers, whereas 4 eyes (21%) achieved final visual acuity of better than 20/200, and in 11 (61%) of 17, proliferative vitreoretinopathy developed over a follow-up of at least 6 months. There were no cases of endophthalmitis or sympathetic ophthalmia. Neither mechanism of injury nor timing of surgery correlated with favorable outcomes. However, entry and exit wounds localized to the anterior half of the globe were associated with favorable anatomic outcome (P<0.005, Fisher exact test, 2-tailed) and visual outcome (P = 0.041, Fisher exact test, 2-tailed). CONCLUSIONS: Perforating globe injuries associated with COT generally result in poor visual and anatomic outcomes despite surgical intervention. Prophylactic measures, such as eye protection, are helpful in reducing the likelihood of perforating injuries; however, novel surgical and pharmacologic therapies will be required to improve the functional and anatomic outcomes of these devastating injuries. AD - Ophthalmology Service, Walter Reed Army Medical Center, Washington, DC, USA. AN - 18672293 AU - Colyer, M. H. AU - Chun, D. W. AU - Bower, K. S. AU - Dick, J. S. AU - Weichel, E. D. DA - Nov DO - 10.1016/j.ophtha.2008.05.013 DP - NLM ET - 2008/08/02 IS - 11 KW - Adult Blast Injuries/*etiology/physiopathology/surgery Eye Enucleation Eye Evisceration Eye Foreign Bodies/*etiology/physiopathology/surgery Eye Injuries, Penetrating/*etiology/physiopathology/surgery Follow-Up Studies Humans *Iraq War, 2003-2011 Male Middle Aged *Military Personnel Retrospective Studies United States Visual Acuity/physiology Vitrectomy Warfare Young Adult LA - eng N1 - 1549-4713 Colyer, Marcus H Chun, Dal W Bower, Kraig S Dick, John S B Weichel, Eric D Journal Article United States Ophthalmology. 2008 Nov;115(11):2087-93. doi: 10.1016/j.ophtha.2008.05.013. Epub 2008 Jul 31. PY - 2008 SN - 0161-6420 SP - 2087-93 ST - Perforating globe injuries during operation Iraqi Freedom T2 - Ophthalmology TI - Perforating globe injuries during operation Iraqi Freedom VL - 115 ID - 81 ER - TY - JOUR AB - Current studies indicate a 0.3-1 % rate of retained surgical items per 1,000 cases in the United States1. This type of adverse event is considered a “never” event; a medical error that should never occur because it is serious and usually preventable. The purpose of this project is twofold; first, to identify risk factors for retained surgical items at BC Children's Hospital and second, to engage front line clinicians in improving current processes for counting and handling incorrect counts. Retrospective chart reviews of the last 50 patients with reported incorrect surgical counts (2012-2013) at BCCH in Vancouver, Canada were conducted to identify common trends. Operating room observations were performed in order to identify themes in team communication and interaction during the count process. Preliminary results from the chart reviews demonstrate trends in the occurrence of incorrect counts and inconsistency in follow-up documentation of investigative measures performed to resolve count discrepancies. Operating theatre observation has enabled the identification of common distractions (e.g.: loud conversations, pagers) and interruptions that can lead to avoidable count discrepancies. Preliminary findings indicate distractions and/or interruptions occurred during the count of 69 % of randomly audited cases. Results indicate that in order to reduce the risk for retained surgical items, we must focus on culture change within the operating theatre that will enhance team communication and aid in the incorporation of evidence-based best practices. Results have also indicated opportunities to improve our current count policy, count process and documentation of the resolution of incorrect counts. AD - A. Bhatti, UCD School of Medicine and Medical Science, University College Dublin, Belfield, Dublin 4, Ireland AU - Bhatti, A. AU - Ferguson, K. AU - Duffy, D. AU - Afshar, K. DB - Embase DO - 10.1007/s11845-013-1039-2 IS - 11 KW - school medicine summer student human awards and prizes prevention operating room documentation medical record review interpersonal communication follow up conversation risk policy medical error Canada patient risk factor evidence based practice pediatric hospital LA - English M3 - Conference Abstract N1 - L71283298 2014-01-10 PY - 2013 SN - 0021-1265 SP - S506 ST - The perfect count: Multidisciplinary strategy for the prevention of retained surgical items T2 - Irish Journal of Medical Science TI - The perfect count: Multidisciplinary strategy for the prevention of retained surgical items UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71283298&from=export http://dx.doi.org/10.1007/s11845-013-1039-2 VL - 182 ID - 467 ER - TY - JOUR AB - Minimally invasive and interventional techniques are increasingly being used in manipulating malpositioned or dislocated intravascular foreign bodies. There is a wide range of available endovascular techniques either for correcting the position of an incorrectly placed endovascular device or for its percutaneous retrieval. We report a case of successful retrieval of a misplaced central venous guiding wire from the left sigmoid dural venous sinus. AD - Department of Interventional Radiology, University Hospital, Stavrakia, Heraklion, Crete, Greece AU - Perdikakis, E. AU - Kehagias, E. AU - Tsetis, D. DB - Scopus IS - 6 KW - Cranial sinus Foreign bodies Surgical procedures, minimally invasive M3 - Article N1 - Export Date: 10 November 2020 PY - 2011 SP - 349-351 ST - Percutaneous retrieval of a misplaced guidewire from the sigmoid dural venous sinus T2 - Chirurgia TI - Percutaneous retrieval of a misplaced guidewire from the sigmoid dural venous sinus UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84857580253&partnerID=40&md5=e0a8f90b4c71d756faa2cd7807cfde39 VL - 24 ID - 1400 ER - TY - JOUR AB - Percutaneous nephrostomy has come a long way in the 27 years since Goodwin et al. devised the procedure as a natural extension of the then-new technique of antegrade pyelography. Our own experience and a review of percutaneous nephrostomy, published in 1978, yielded reports of only 516 such procedures through March of 1977, most of which had been performed during the preceding five years. Since then, the literature on percutaneous nephrostomy and related techniques has exploded, and the number of procedures performed is beyond count. Percutaneous nephrostomy is no longer merely an end in itself but also a convenient access to the upper urinary tract for insertion of ureteral stents; dissolution, extrusion, or extraction of calculi; closure of fistulas; administration of drugs; extraction of foreign bodies; insertion of brush biopsy instruments and nephroscopes; and the performance of ureteral meatotomy. These exciting spin-offs of percutaneous nephrostomy are described elsewhere in this symposium. This article reviews the status of percutaneous nephrostomy, and represents a synthesis of the literature and personal experience. AD - Dept. Radiol., Salem Mem. Hosp., Salem, OR 97309 AU - Stables, D. P. DB - Embase Medline IS - 1 KW - diagnosis kidney methodology nephrostomy review therapy LA - English M3 - Article N1 - L12180686 1982-04-25 PY - 1982 SN - 0094-0143 SP - 15-29 ST - Percutaneous nephrostomy: Techniques, indications, and results T2 - Urologic Clinics of North America TI - Percutaneous nephrostomy: Techniques, indications, and results UR - https://www.embase.com/search/results?subaction=viewrecord&id=L12180686&from=export VL - 9 ID - 683 ER - TY - JOUR AB - In this review the technique, indication for and complications of percutaneous nephrostomy (PCN) and antegrade ureter stent insertion are described. In the majority of the cases PCN is performed to relieve urinary obstruction, which can be of benign or malignant nature. Another indication for PCN is for treatment of urinary fistulas. PCN can be performed under ultrasound and/or fluoroscopic guidance, with a success rate of more than 90%. The complication rate is approximately 10% for major and minor complications together and 4-5% for major complications only. Percutaneous antegrade double-J stent insertion usually is performed if retrograde ureter stenting has not been successful. However, especially in malignant obstructions, the success rate for antegrade stenting is higher than for retrograde transvesical double-J stent insertion. In the case of severe infection and bleeding after PCN JJ-stent insertion may be contraindicated so long as there is no sufficient concomitant drainage via a PCN. Lower urinary tract dysfunction should be excluded before stent placement. The complication rate is 2-4%. Consequent stent surveillance with regular stent exchange is mandatory. © Springer-Verlag 2006. AD - Department of Radiology, Klagenfurt General Hospital, St. Veiter Strasse 47, 9020 Klagenfurt, Austria Department of Radiology, University Hospital of Graz, Graz, Austria AU - Hausegger, K. A. AU - Portugaller, H. R. DB - Scopus DO - 10.1007/s00330-005-0136-7 IS - 9 KW - Interventional procedures Kidney Percutaneous nephrostomy Stents Ureter Urinary tract obstruction M3 - Review N1 - Cited By :98 Export Date: 10 November 2020 PY - 2006 SP - 2016-2030 ST - Percutaneous nephrostomy and antegrade ureteral stenting: Technique - Indications - Complications T2 - European Radiology TI - Percutaneous nephrostomy and antegrade ureteral stenting: Technique - Indications - Complications UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33746912673&doi=10.1007%2fs00330-005-0136-7&partnerID=40&md5=9cc6b7f58130cbd53e21c90d948e5883 VL - 16 ID - 1578 ER - TY - JOUR AB - Image-guided retrieval of endovascular devices such as inferior vena cava filters, guidewires, and stents is well reported, though there is a paucity of published reports on biliary, genitourinary, or gastrointestinal foreign body retrieval utilizing percutaneous endoscopy, particularly when it is performed solely by interventional radiologists. In cases of failed traditional endoscopic techniques or to evade more invasive surgical options, percutaneous endoscopy can be an adjunctive tool employed by interventional radiologists to extract foreign bodies. In this article, clinical evaluation, perioperative management, and procedural techniques for biliary, genitourinary, and gastrointestinal endoscopy for foreign body retrieval are reviewed. © 2019 Elsevier Inc. AD - Department of Radiology, Division of Vascular and Interventional Radiology, The Ohio State University Wexner Medical Center, Columbus, OH, United States Department of Biology, University of Louisville, Louisville, KY, United States Division of Interventional Radiology, Department of Radiology. University of Washington, 1959 Northeast Pacific Street, SeattleWA 98195, United States Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States Department of Radiology, Division of Vascular and Interventional Radiology, UCLA Medical Center, Los Angeles, CA, United States AU - Khayat, M. AU - Khayat, A. AU - Chick, J. F. B. AU - Healey, T. L. AU - Srinivasa, R. N. DB - Scopus DO - 10.1053/j.tvir.2019.04.007 IS - 3 KW - endobronchial forceps endoscopic retrieval foreign body removal gastroscopy interventional radiology Percutaneous endoscopy M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 149-153 ST - Percutaneous Interventional Radiology-Operated Endoscopy for Foreign Body Removal T2 - Techniques in Vascular and Interventional Radiology TI - Percutaneous Interventional Radiology-Operated Endoscopy for Foreign Body Removal UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85066413547&doi=10.1053%2fj.tvir.2019.04.007&partnerID=40&md5=6647059c5b23bd046e16a53355c7316c VL - 22 ID - 996 ER - TY - JOUR AB - 36-year-old HIV-positive man presented with symptoms of redness, blurred vision and foreign body sensation in his right eye for 3 months. The slit lamp examination revealed deep stromal infiltration with a feathery margin in an otherwise minimal anterior chamber reaction. A corneal scraping was negative. Confocal microscopy demonstrated an abnormal large hyper-reflective oval shape in the corneal stroma. Corneal infiltration did not show improvement after topical, intrastromal and intracameral antifungal treatment. Therapeutic penetrating keratoplasty was performed to eradicate the infection. Corneal button culture and histopathological results confirmed the diagnosis of Penicillium marneffei keratitis. No recurrent infection occurred after corneal transplantation. This appears to be the first report of P. marneffei keratitis in an HIV-infected patient. Although it is an uncommon condition, it should be one of the differential diagnoses in an HIV-infected patient presenting with keratitis. AD - Faculty of Medicine, Department of Ophthalmology, Khon Kaen University, Moung, Thailand Department of Ophthalmology, Khon Kaen University, Khon Kaen, Thailand AU - Anutarapongpan, O. AU - Thanathanee, O. AU - Suwan-Apichon, O. C7 - 216139 DB - Scopus DO - 10.1136/bcr-2016-216139 M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2016 ST - Penicillium keratitis in a HIV-infected patient T2 - BMJ Case Reports TI - Penicillium keratitis in a HIV-infected patient UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84983656121&doi=10.1136%2fbcr-2016-216139&partnerID=40&md5=386bf3e13115749901553ab4d58cdbd1 VL - 2016 ID - 1209 ER - TY - JOUR AB - An unusual case of a penetrating grass awn in an eyelid of a dog is reported. A 6-month-old mixed breed dog was referred to the Ophthalmology Unit of the Veterinary Teaching Hospital of Camerino University for anorexia, lethargy, left monolateral ocular swelling and pain to the left eye, present from 1 month. Ophthalmic examination of the left eye showed copious and purulent discharge, and ultrasonography revealed the presence of an abscess containing a grass foreign body. The grass awn was surgically removed. Three days after surgery, the dog showed a marked improvement, with a total resolution obtained in 7 days. To the authors’ knowledge, penetrating foreign bodies such as the one of this paper have never been described before in literature. © 2017, Società Italiana di Ultrasonologia in Medicina e Biologia (SIUMB). AD - Veterinary Teaching Hospital, University of Camerino, via Circonvallazione 93/95, Matelica (MC), I-62024, Italy AU - Marchegiani, A. AU - Fruganti, A. AU - Cerquetella, M. AU - Cassarani, M. P. AU - Laus, F. AU - Spaterna, A. DB - Scopus DO - 10.1007/s40477-016-0234-1 IS - 1 KW - Dog Foreign body Grass awn Lid abscess Swollen eyelid Ultrasonography M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2017 SP - 81-84 ST - Penetrating palpebral grass awn in a dog: Unusual case of a penetrating grass awn in an eyelid T2 - Journal of Ultrasound TI - Penetrating palpebral grass awn in a dog: Unusual case of a penetrating grass awn in an eyelid UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85014504243&doi=10.1007%2fs40477-016-0234-1&partnerID=40&md5=570845447bd5ccdc6b106ad22e27a3e0 VL - 20 ID - 1141 ER - TY - JOUR AB - Ocular trauma is the leading cause of acquired monocular blindness, accounting for 1.97-6% of such cases. Particularly, penetrating ocular injuries are among the most common eye injuries with this kind of outcome. Early diagnosis and prompt management are crucial to avoid complications, and the especially dreaded enucleation. In this article, the authors describe the clinical management, and evaluate the visual and anatomical results obtained in a case of ocular injury with retained intraocular foreign body (IOFB) in a 20-year old female patient. The course of treatment involved a combination of penetrating keratoplasty with a temporary keratoprosthesis, phacoemulsification with intraocular lens implantation and pars plana vitrectomy. At three years from the initial injury, the patient was able to count fingers at 30 centimetres and anatomical restitutio ad integrum of the globe had been achieved. AD - Department of Ophthalmology, University of Rome "Campus Bio-Medico", Rome, Italy, E-mail: s.sorrentino@unicampus.it. Legal Medicine and Social Security Services, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy. Department of Experimental Medicine, Second University of Naples, Naples, Italy. Section of Legal Mediciine, University of Rome "Tor Vergata", Rome, Italy. "GB Bietti" Foundation for Study and Research in Ophthalmology, Rome, Italy. Department of Ophthalmology, University of Rome "Campus Bio-Medico", Rome, Italy. AN - 28358438 AU - Sorrentino, S. AU - Marsella, L. T. AU - Feola, A. AU - Marino, V. AU - Billi, B. DA - May 13 DO - 10.7727/wimj.2014.142 DP - NLM ET - 2015/05/13 IS - 2 KW - Intraocular foreign body keratoprosthesis vitrectomy LA - eng N1 - Sorrentino, S Marsella, L T Feola, A Marino, V Billi, B Journal Article Jamaica West Indian Med J. 2015 May 13;65(2):391-394. doi: 10.7727/wimj.2014.142. PY - 2015 SN - 0043-3144 (Print) 0043-3144 SP - 391-394 ST - Penetrating Ocular Trauma with Retained Intraocular Foreign Body: Management, Follow-up and Medico-legal Evaluation T2 - West Indian Med J TI - Penetrating Ocular Trauma with Retained Intraocular Foreign Body: Management, Follow-up and Medico-legal Evaluation VL - 65 ID - 161 ER - TY - JOUR AB - Retropharyngeal abscess caused by pharyngeal penetrating injury is a rare but life threatening condition with extensive fasciitis and possible gas accumulating in the prevertebral fascia. Pharyngeal penetrating injuries are uncommon, except for those with a definite history of foreign body swallowing or external traumatic injury. We described a 24-year-old man, who sustained retropharyngeal abscess with gas formation in the retropharyngeal soft tissue after swallowing and vomiting a pair of scissors. In the emergency department (ED), an early computed tomography scan helped with the diagnosis and showed the extent of the ailment, which was promptly treated with surgical debridement and drainage. Broad-spec-trum antibiotics were started as soon as possible, while the clinical suspicion was initially made. The patient was treated promptly and discharged without serious complications. © 2010 JMS. AD - Department of Emergency Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan Division of Emergency Medicine, Tri-Service General Hospital Penghu Branch, Magong, Penghu, Taiwan AU - Lin, C. H. AU - Chu, Y. S. AU - Liao, C. F. AU - Chen, Y. L. AU - Hsu, K. C. DB - Scopus IS - 2 KW - Depression Penetrating injury Prevertebral soft tissue Retropharyngeal abscess M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2010 SP - 071-073 ST - Penetrating injury to the pharynx by scissors leading to retropharyngeal abscess in a depressed man T2 - Journal of Medical Sciences TI - Penetrating injury to the pharynx by scissors leading to retropharyngeal abscess in a depressed man UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77951957223&partnerID=40&md5=3dad2e2e32435a115dd092b73615c0de VL - 30 ID - 1458 ER - TY - JOUR AB - Study Design.: Case report. Objective.: To report an extremely rare case of combined penetrating injury to rectum and vertebral body by steel bar causing cauda equina syndrome. Summary of Background Data.: Only one similar case has been reported. Our case was more severe and posed more challenges to physicians. Methods.: A 37-year-old male had a penetrating rectal injury by a long steel bar as a result of a falling accident. He was firstly treated with removal of the bar, debridement, and fecal diversion. Spine and cauda equina injuries were found the second day by lumbar and sacral CT. Because of infection after the first surgery, decompressive surgery was performed 2 months from injury. Cerebrospinal fluid fistula happened on the 12th day after surgery which was managed by debridement, irrigation and drainage, suture of the leaking skin and combined use of antibiotics. Results.: When being discharged, he could ambulate independently but could not control his voiding. The colostomy and urinary canal was preserved during the follow-up. Conclusion.: Steel bar penetrating injury of rectum and vertebral body can be severe and cause complex injuries. Complications included infection and cerebrospinal fluid fistula. Thorough history and physical examination and CT and MRI inspection are very important for timely diagnosis and early treatment of spine and cauda equina injuries. Dural tear should be carefully inspected and repaired during posterior lumbar decompression surgery. Cooperation of experienced surgeons from orthopedics and gastrointestinal department is needed to give the patient the most appropriate treatment and improve prognosis. Copyright © 2011 Lippincott Williams & Wilkins. AD - Department of Orthopaedics, West China Hospital, Sichuan University, Sichuan, China Department of Pediatrics, West China Second University Hospital, Sichuan University, Sichuan, China AU - Zhou, Z. AU - Song, Y. AU - Cai, Q. AU - Li, T. AU - Liu, H. DB - Scopus DO - 10.1097/BRS.0b013e3181fab574 IS - 12 KW - cauda equina syndrome cerebrospinal fluid fistula penetrating injury rectum steel bar vertebral body M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2011 SP - E803-E807 ST - Penetrating injury of rectum and vertebral body by steel bar causing cauda equina syndrome T2 - Spine TI - Penetrating injury of rectum and vertebral body by steel bar causing cauda equina syndrome UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79957699303&doi=10.1097%2fBRS.0b013e3181fab574&partnerID=40&md5=90a5b7fa7cd005796667c1ee26faf3ba VL - 36 ID - 1420 ER - TY - JOUR AB - A patient who presented with penetrating chest trauma and massive hemothorax by a small stone required tube insertion as part of his therapy. In contrast, hemodynamically unstable patients require emergency department thoracotomy to stop the bleeding and evacuate the pleural space. This is treated with an intercoastal chest drain. The management of the traumatic hemothorax by closed thoracic drainage is an effective treatment for traumatic hemothorax induced by a small foreign body, since tube drainage can avoid the incidence of thoracotomy related complications. © 2018, Scientific Publishers of India. All rights reserved. AD - Department of Cardiothoracic Surgery, The Lu'an Affiliated Hospital, Anhui Medical University, No. 21 of Wanxi West Road, Lu'an City, China AU - Huang, H. P. AU - Ning, C. D. AU - Lu, B. AU - Huo, Q. L. DB - Scopus IS - 22 KW - Closed thoracic drainage Emergency treatment Foreign body Haemothorax Penetrating chest trauma M3 - Article N1 - Export Date: 10 November 2020 PY - 2017 SP - 9849-9850 ST - Penetrating chest trauma with massive hemothorax by a small stone T2 - Biomedical Research (India) TI - Penetrating chest trauma with massive hemothorax by a small stone UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85042553569&partnerID=40&md5=a8150cfcf35dbb8aa236c0ab5e121bb7 VL - 28 ID - 1152 ER - TY - JOUR AB - Penetrating trauma of the abdomen no longer warrants mandatory laparotomy. Clinical predictors of the need for operation should first be employed. Patients who do not meet these clinical criteria undergo a selective diagnostic approach on the basis of mechanism and site of injury and the experience and expertise of the institution. Through the use of algorithms, this article reviews the management of stab and gun shot wounds to the abdomen. AD - Department of Emergency Medicine, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28232-2861, United States AU - Marx, J. A. DB - Scopus IS - 1 M3 - Review N1 - Cited By :4 Export Date: 10 November 2020 PY - 1993 SP - 125-135 ST - Penetrating abdominal trauma T2 - Emergency Medicine Clinics of North America TI - Penetrating abdominal trauma UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027401681&partnerID=40&md5=46281cd5587593af3e83ab1dd854990e VL - 11 ID - 1731 ER - TY - JOUR AB - Pelvic actinomycosis associated with the use of an intrauterine device (IUD) is a recently recognized combination. The usual manifestations of the disease are those of mild pelvic inflammatory disease (PID) in a woman who uses an IUD. The disease is easily recognized on Papanicolaou-stained cervicovaginal smears. Early treatment involves removal of the IUD and administration of penicillin. Rarely, the disease may be serious and may require drainage of intra-abdominal abscesses, hysterectomy with salpingo-oophorectomy, or both. The second known death from pelvic actinomycosis associated with use of an IUD is reported. Recent reports suggest that pelvic inflammatory disease (PID) is more common among users of the IUD than among those using other forms of contraception and that there is an association between IUD use and pelvic actinomycosis. In 1979 a woman at the University of New Mexico Hospital died from pelvic actinomycosis, the 2nd reported death from this disease associated with the use of an IUD, although her death from pulmonary embolus and Candida endocartidis should more appropriately be considered a complication of intravenous hyperalimentation. At least 25 patients are reported to have had serious pelvic actinomycosis associated with the use of an IUD. No particular type of IUD seems less likely to be associated with actinomycosis. Actinomyces are normally present in the gut and oropharynx, so that inoculation of the vagina with stool or saliva in combination with trauma induced by the foreign body such as an IUD may allow the actinomyces to enter tissues. Actinomyces are easily detected by Papanicolaou-stained cervicovaginal smears and are present in as many as 25% of symptomatic women using IUDs. Culture techniques usually fail in detecting actinomyces, the need for an anaerobic environment or overgrowth by bacteria which invariably accompany actinomyces are the usual causes of failure. Usual signs of IUD-associated actinomycosis are pelvic and lower abdominal or back pain, vaginal discharge, fever, and elevation of leukocyte count which are similar to symptoms of mild PID. Therefore these symptoms demand a Papanicolaou-stained cervicovaginal smear and search for actinomyces. Treatment includes removal of the IUD and administration of penicillin. However at least 1 patient after receiving treatment returned later with actinomycotic tubo-ovarian and subphrenic abscesses. A period of at least 4-6 weeks of therapy is usually recommended. Most patients with pelvic masses underwent hysterectomy and bilateral salpingo-oophorectomy in addition to penicillin and IUD removal; a few were successfully treated with drainage of an intra-abdominal abscess. AD - Dept. Surg., Univ. New Mexico Sch. Med., Albuquerque, NM, United States AU - Doberneck, R. C. DB - Scopus IS - 1 M3 - Article N1 - Cited By :16 Export Date: 10 November 2020 PY - 1982 SP - 25-27 ST - Pelvic actinomycosis associated with use of intrauterine device: A new challenge for the surgeon T2 - American Surgeon TI - Pelvic actinomycosis associated with use of intrauterine device: A new challenge for the surgeon UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0020086476&partnerID=40&md5=631a05393c1e430dfd78e4d250b2a8c8 VL - 48 ID - 1763 ER - TY - JOUR AB - The authors describe two women with pelvic pain, long-term use of an intrauterine device, and a pelvic mass due to Actinomyces israelii. The diagnostic imaging findings were nonspecific but included mass effect and mucosal irregularity of the rectosigmoid colon at barium enema examination and complex masses and inflammatory changes at computed tomography and magnetic resonance imaging. Radiologists should be aware of the imaging findings of this potentially lethal but curable condition. 2 cases of pelvic Actinomycosis both in women 40 years of age, with IUDs in place for 8 and 10 years respectively, were diagnosed with the aid of radiologic techniques including barium enema, computed tomography (CT) and magnetic resonance imaging (MR). The 1st woman had experienced malaise, night sweats and a weight loss of 15 lb. over 2-3 months, then felt an epigastric mass for 5 days. She has endometritis, elevated white blood cell count, and large, tender, bilateral adnexal masses. Inflammatory changes and multilocular fluid collections were demonstrated by enhanced CT. Aspiration of the epigastric mass yielded sulfur granules and anaerobic bacteria. She was successfully treated with penicillin, gentamycin and clindamycin. The 2nd woman had a 2-month history of abdominal pain, a pelvic mass and an elevated white blood cell count. Enhanced CT, barium enema and sigmoidoscopy demonstrated a mass between the uterus and bowel, with mural invasion of the sigmoid colon. A 5 x 6 cm left-sided tubo-ovarian abscess adhering to the colon, bladder and left pelvic sidewall was excised at laparotomy. She remained asymptomatic at 6 months. This lethal but curable condition is caused by Actinomyces israelii, an opportunistic gram-positive bacteria usually introduced by foreign bodies, surgery or trauma. CT and MR were helpful in diagnosing the relatively nonspecific signs and symptoms in these cases. eng AD - Department of Radiology, Medical University of South Carolina, Charleston 29425-0720. AN - 2911683 AU - O'Connor, K. F. AU - Bagg, M. N. AU - Croley, M. R. AU - Schabel, S. I. DA - Feb DO - 10.1148/radiology.170.2.2911683 DP - NLM ET - 1989/02/01 IS - 2 KW - Actinomycosis/diagnosis/diagnostic imaging/*etiology Adult Female Humans Intrauterine Devices/*adverse effects Magnetic Resonance Imaging Pelvic Inflammatory Disease/diagnosis/diagnostic imaging/*etiology Tomography, X-Ray Computed *Adhesions Americas *Antibiotics *Bacterial And Fungal Diseases Contraception Contraceptive Methods Developed Countries Diseases Drugs *Endometritis *Endoscopy Examinations And Diagnoses Family Planning *Granulomas Infections *Iud North America Northern America *Pelvic Infections *Physical Examinations And Diagnoses Reproductive Tract Infections Signs And Symptoms South Carolina Treatment *Ultrasonics United States LA - eng N1 - O'Connor, K F Bagg, M N Croley, M R Schabel, S I Case Reports Journal Article United States Radiology. 1989 Feb;170(2):559-60. doi: 10.1148/radiology.170.2.2911683. PY - 1989 SN - 0033-8419 (Print) 0033-8419 SP - 559-60 ST - Pelvic actinomycosis associated with intrauterine devices T2 - Radiology TI - Pelvic actinomycosis associated with intrauterine devices VL - 170 ID - 17 ER - TY - JOUR AB - Purpose: We determine the clinical characteristics, visual and anatomical outcomes, and factors associated with poor visual outcome and anatomical success in pediatric open-globe injuries (OGI). Methods: The records of patients aged 17 years and younger who had undergone surgical intervention after OGI between January 2000 and June 2010 were reviewed retrospectively. Results: In total, 182 patients were enrolled in the study (70.9 % males, 29.1 % females; mean age: 8.6 ± 4.5 years [range 1–17 years]). Injuries occurred mostly at home (45.1 %). Objects most often causing the ocular trauma were sharp objects (74.1 %). Over one-third of the eyes (39.7 %) had final visual acuities of 20/200 or better. Anatomical success was achieved in 76.9 % of eyes. Time between primary globe repair and secondary surgical intervention was 61.4 ± 144 days. Visual outcomes were poor in eyes with initial visual acuity less than for counting fingers, retinal detachment, proliferative vitreoretinopathy, and endophthalmitis. Anatomical success rates were low with retinal detachment. Conclusion: Visual outcomes seem to be poor in more than half of the patients despite advanced microsurgical techniques. © 2015, Springer-Verlag Berlin Heidelberg. AD - Department of Ophthalmology, Muğla Sıtkı Koçman University School of Medicine, Muğla, Turkey Department of Ophthalmology, Gazi University Medical School, Ankara, Turkey Department of Ophthalmology, Düzce State Hospital, Düzce, Turkey Göz Hastalıkları Anabilim Dalı, Muğla Sıtkı Koçman University, Muğla, 48000, Turkey AU - Sul, S. AU - Gurelik, G. AU - Korkmaz, S. AU - Ozdek, S. AU - Hasanreisoglu, B. DB - Scopus DO - 10.1007/s00417-015-3087-y IS - 7 KW - Endophthalmitis Open globe injury Retinal detachment M3 - Article N1 - Cited By :9 Export Date: 10 November 2020 PY - 2016 SP - 1405-1410 ST - Pediatric open-globe injuries: clinical characteristics and factors associated with poor visual and anatomical success T2 - Graefe's Archive for Clinical and Experimental Ophthalmology TI - Pediatric open-globe injuries: clinical characteristics and factors associated with poor visual and anatomical success UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84935096670&doi=10.1007%2fs00417-015-3087-y&partnerID=40&md5=65ffed3e24078f60a5792523b61830b3 VL - 254 ID - 1179 ER - TY - JOUR AB - Purpose To describe the etiology, diagnosis, management, and outcomes of pediatric infectious endophthalmitis cases at University Hospital, Newark, NJ over 11 years, 2001-2011. Methods Retrospective series. Data were collected on demographics, presenting clinical findings, management, culture results, and visual and anatomic outcomes. Results Seven cases of infectious pediatric endophthalmitis were identified in six patients. Two patients were male, and four were female. Mean presenting age was 6 years (range 4 weeks to 16 years). The most common etiology was trauma, accounting for 3 out of 7 cases (43%), of which one featured an intraocular foreign body. Two of 7 cases were caused by endogenous bacterial spread (29%), and 2 of 7 were secondary to bleb infection (29%). Patients presented most commonly with symptoms of pain (71%), photophobia (43%), and blurred vision (43%) and signs of vitritis (100%), anterior chamber fibrinous exudates (57%), conjunctival hyperemia (57%), chemosis (71%), and hypopyon (29%). All 3 trauma cases had uveal prolapsed in zone III. None presented with retinal detachment. Only one of three vitreous cultures was positive (33%) and grew Group B Streptococcus. Three cases underwent both pars plana vitrectomy (PPV) and intravitreal antibiotics (43%), and one only intravitreal antibiotics (14%). Best recorded visual acuity after resolution of infection was 20/400 in one patient, counts fingers in another, and no light perception in the remaining 5 eyes. One underwent primary enucleation (14%), one secondary enucleation (14%), and 2 became phthisical (29%). Conclusions Endophthalmitis is a rare but calamitous condition usually resulting in blindness. Our small series finds traumatic open globe injury as the most common cause of infectious endophthalmitis. Despite emergent treatment, patients are frequently left with no light perception in the affected eye. AD - B. Jones, Institute of Ophthalmology and Visual Science, UMDNJ - New Jersey Medical School, Newark, NJ, United States AU - Jones, B. AU - Athwal, L. AU - Zarbin, M. AU - Langer, P. AU - Bhagat, N. DB - Embase IS - 15 KW - antibiotic agent adolescent anterior eye chamber blindness blurred vision case study chemosis child complication conference abstract conjunctival hyperemia endophthalmitis exudate female finger human hypopyon intraocular foreign body major clinical study male nonhuman pain pars plana vitrectomy perception photophobia preschool child retina detachment retrospective study Streptococcus agalactiae visual acuity vitreous body vitritis LA - English M3 - Conference Abstract N1 - L628709696 2019-08-01 PY - 2013 SN - 1552-5783 ST - Pediatric infectious endophthalmitis: A case series T2 - Investigative Ophthalmology and Visual Science TI - Pediatric infectious endophthalmitis: A case series UR - https://www.embase.com/search/results?subaction=viewrecord&id=L628709696&from=export VL - 54 ID - 481 ER - TY - JOUR AB - Small bowel obstruction (SBO) secondary to fruit pit impaction is rare. The presence of an ovoid, stony body in the bowel lumen on radiologic imaging in a patient presenting with signs and symptoms of SBO is likely to raise concern for gallstone ileus. We report the case of a 56-year-old man who presented with a 1-day history of intermittent left-sided abdominal pain and nausea associated with a single episode of vomiting. CT scan of the abdomen and pelvis revealed a 3.3 cm impacted stony mass in the terminal ileum resulting in high-grade partial SBO. The mass had a hypodense centre encased within a hyperdense, ridged outer layer. The diagnostic impression was gallstone ileus. The object was removed via enterotomy and was found to be a peach pit. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ. AD - Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States Department of Surgery, Mount Sinai Health System, New York, NY, United States Department of Surgery, Beth Israel Medical Center, New York, NY, United States AU - Syed, A. S. AU - Bonte, A. AU - Allaham, L. A. AU - Goodman, E. R. C7 - e235363 DB - Scopus DO - 10.1136/bcr-2020-235363 IS - 7 KW - gastrointestinal surgery radiology M3 - Article N1 - Export Date: 10 November 2020 PY - 2020 ST - Peach pit impaction presenting as gallstone ileus T2 - BMJ Case Reports TI - Peach pit impaction presenting as gallstone ileus UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85088879924&doi=10.1136%2fbcr-2020-235363&partnerID=40&md5=6f38a2ea2b37c39a96c70102b6dc5639 VL - 13 ID - 957 ER - TY - JOUR AB - Introduction: This study tracks the microbiology of packs and infections in damage-control trauma patients to determine whether the packs cause infections. Methods. The peritoneum and abdominal packs were cultured in patients who survived to re-operation. The study recorded all positive cultures, pack count, packing duration, number of operations, and infections. Results: Thirty-five patients were studied. Twenty-eight patients survived; seven died. Packs were cultured in 29 patients. Data for 291 cultures collected. Pack cultures were positive in 20 patients and negative in nine. Positive pack cultures grew skin and gut flora. Twenty-one patients had infections, 14 did not. Organisms from positive pack cultures did not contribute to subsequent infections or mortality. Microbes and sites of infections were consistent with SICU patients. Conclusions. Intra-abdominal packs are contaminated with skin and gut flora. These contaminants, however, do not contribute to subsequent infections. Pathogens from subsequent infections were typical for ICU infections. AD - T.S. Granchi, Michael E. DeBakey Dept. of Surgery, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, United States AU - Granchi, T. S. AU - Abikhaled, J. A. AU - Hirshberg, A. AU - Wall, M. J. AU - Mattox, K. L. AU - Fry, D. E. AU - Smathers, H. M. AU - Salomone, J. P. AU - Ivatury, R. R. AU - Feliciano, D. V. AU - Granchi, T. DB - Embase Medline DO - 10.1097/01.TA.0000107840.72777.D3 IS - 1 KW - Acinetobacter adolescent adult clinical article conference paper female gauze pack human injury intensive care unit intestine flora male microbiological examination mortality priority journal reoperation Staphylococcus surgical sponge survival LA - English M3 - Conference Paper N1 - L38182160 2004-02-26 PY - 2004 SN - 0022-5282 SP - 45-51 ST - Patterns of Microbiology in Intra-abdominal Packing for Trauma T2 - Journal of Trauma - Injury, Infection and Critical Care TI - Patterns of Microbiology in Intra-abdominal Packing for Trauma UR - https://www.embase.com/search/results?subaction=viewrecord&id=L38182160&from=export http://dx.doi.org/10.1097/01.TA.0000107840.72777.D3 VL - 56 ID - 637 ER - TY - JOUR AB - Retained surgical items were the most frequently reported sentinel event in 2010, according to The Joint Commission. Perioperative nurse leaders at Children's Hospital Boston, a pediatric teaching hospital, conducted a quality improvement initiative to reduce or eliminate incorrect counts and count discrepancies, which increase the risk of an item being unintentionally retained after surgery. Work included educating the perioperative staff members, standardizing count practices, formally reviewing every reported count discrepancy with the nursing team, and reviewing and revising the count policy for prevention of retained surgical items. The initiative reduced the number of incorrect counts and count discrepancies by 50% between 2009 to 2010. These initiatives continue to be expanded, and the results have been sustained on an ongoing basis. AD - Children’s Hospital, Boston, MA, USA. AN - 22201575 AU - Norton, E. K. AU - Martin, C. AU - Micheli, A. J. DA - Jan DO - 10.1016/j.aorn.2011.06.007 DP - NLM ET - 2011/12/29 IS - 1 KW - Boston Documentation/methods/standards Foreign Bodies/*prevention & control Hospitals, Pediatric/organization & administration Humans Intraoperative Complications/prevention & control Length of Stay Patient Care Team/organization & administration *Perioperative Nursing/organization & administration/standards Program Development Quality Improvement/*organization & administration Risk Assessment *Surgical Instruments Surgical Sponges LA - eng N1 - 1878-0369 Norton, Elizabeth K Martin, Cornelia Micheli, Anne J Journal Article United States AORN J. 2012 Jan;95(1):109-21. doi: 10.1016/j.aorn.2011.06.007. PY - 2012 SN - 0001-2092 SP - 109-21 ST - Patients count on it: an initiative to reduce incorrect counts and prevent retained surgical items T2 - Aorn j TI - Patients count on it: an initiative to reduce incorrect counts and prevent retained surgical items VL - 95 ID - 120 ER - TY - JOUR AB - Background: When measured objectively, adults with ACL reconstruction (ACLR) are 2.5 times less likely to be physically active than by their healthy counterparts. Currently, it is unclear if patientreported physical activity (PA) is related to objectively-measured PA among high school-aged individuals with ACLR. Purpose: To evaluate the relationship between patient-reported and objectively-measured moderate-to-vigorous PA (MVPA) among high school-aged individuals 6-months after ACLR. Methods: Seventeen participants (age= 15.9±1.3 years, BMI= 24.7±5.1 kg/m2, months since surgery= 6.3±0.7, graft source= 13 hamstring autograft, 3 patellar tendon autograft, and 1 quadriceps tendon autograft, ACL-RSI= 71.3±24.3) with primary unilateral ACLR were enrolled 6±1 months after surgery as part of a prospective cohort study. Participants completed the Tegner Activity and Marx Activity Scales to assess current physical activity level. Participants also completed the International Physical Activity Questionnaire Short Form (IPAQ-SF) to assess patient-reported MVPA (min/day). Objectively-measured MVPA (min/day) and step count (steps/day) were assessed using ActiGraph GTX9-Link accelerometers worn at the hip over a period of no less than 7 days. Wear time (min/day) was validated using recommendations of Choi et al and Evenson's child cutpoints were utilized to categorize PA as light, moderate, vigorous, or very vigorous. Relationships between objectively-measured and patient-reported measures of physical activity were assessed using partial correlations (r) while controlling for total monitor wear-time. We also compared the number of participants who met physical activity guidelines (60 min/day MVPA) via patient-report and objective monitoring using a Fischer's exact test. Results: Participants reported median Tegner activity levels of 5 [range: 5,9] and Marx activity scores of 16 [range: 4,16], and average IPAQ-SF MVPA of 130±80 [range: 0,300] min/day. Objectively, partipants engaged in 26±14 [9,60] min/day of MVPA and took 6140±1691 [range: 3613,9147] steps/day. Current Tegner activity level was moderately correlated to objectivelymeasured MVPA (r = 0.65) but Marx Activity Score (r= 0.14) and IPAQ-SF MVPA (r= 0.01) were not related to objectively-measured MVPA (Figure 1). Individuals who reported meeting MVPA guidelines were no more likely to actually meet objectively-measured MVPA guidelines as compared to participants who reported not meeting guidelines (OR= 1.08, CI= 0.93,1.25, p= 0.99). Conclusion: Objectively, 5.9% of participants were categorized as physically active 6-months following ACLR despite the fact that 82.4% of participants reported meeting PA guidelines. The relationship between objective and patient-reported measures of PA among high school-aged participants months post-ACLR is limited and utilization of patient-reported PA measures in this population should be done with caution.(Table Presented). AD - C. Kuenze, Michigan State University, United States AU - Kuenze, C. AU - Lisee, C. AU - Triplett, A. AU - Birchmeier, T. AU - Straus, M. W. AU - Wilcox, C. L. AU - Schorfhaar, A. AU - Joseph, S. AU - Shingles, M. DB - Embase DO - 10.1177/2325967120S00156 IS - 4 KW - accelerometer actigraph adolescent anterior cruciate ligament reconstruction body mass child clinical article cohort analysis conference abstract controlled study female hamstring muscle high school hip human international physical activity questionnaire male outcome assessment patellar ligament practice guideline prospective study quadriceps tendon step count Tegner activity score tendon graft LA - English M3 - Conference Abstract N1 - L633067863 2020-10-15 PY - 2020 SN - 2325-9671 ST - Patient-reported and objective measures of physical activity are not related 6-months after ACL reconstruction T2 - Orthopaedic Journal of Sports Medicine TI - Patient-reported and objective measures of physical activity are not related 6-months after ACL reconstruction UR - https://www.embase.com/search/results?subaction=viewrecord&id=L633067863&from=export http://dx.doi.org/10.1177/2325967120S00156 VL - 8 ID - 282 ER - TY - JOUR AD - Department of Surgery, Jesse Brown Veterans Administration and Medical Center, 820 S Damen Ave, Chicago, IL 60612, United States Case Western Reserve School of Medicine, Cleveland, OH, United States Department of Radiology, Jesse Brown Veterans Administration and Medical Center, Chicago, IL, United States AU - Vitello, J. M. AU - Vitello, D. J. AU - Bermudez-Allende, M. DB - Scopus DO - 10.1001/jama.2019.6849 IS - 1 M3 - Short Survey N1 - Export Date: 10 November 2020 PY - 2019 SP - 71-72 ST - A Patient with Abnormal Abdominal CT Scan Findings T2 - JAMA - Journal of the American Medical Association TI - A Patient with Abnormal Abdominal CT Scan Findings UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85066987241&doi=10.1001%2fjama.2019.6849&partnerID=40&md5=b7118f2eb23a47b7c62c5d0cff4ff7ae VL - 322 ID - 1004 ER - TY - JOUR AD - Abell-Hanger Professor, Harris College of Nursing and Health Sciences and School of Nurse Anesthesia, Texas Christian University, Fort Worth, TX AN - 105421681. Language: English. Entry Date: 20090911. Revision Date: 20150820. Publication Type: Journal Article. Journal Subset: Core Nursing AU - Cheek, D. J. AU - Jones, T. S. DB - ccm DO - 10.1097/01.NURSE.0000358564.46832.18 DP - EBSCOhost IS - 8 KW - Intraoperative Complications -- Prevention and Control Patient Safety -- Standards Perioperative Care -- Standards Postoperative Complications -- Prevention and Control Quality Improvement Risk Management Airway Management Drug Hypersensitivity Operating Room Personnel Protocols Surgical Count Procedure Surgical Patients World Health Organization Wrong Site Surgery -- Prevention and Control N1 - Nursing; Peer Reviewed; USA. NLM UID: 7600137. PMID: NLM19633492. PY - 2009 SN - 0360-4039 SP - 14-15 ST - Patient safety. Safe surgery initiative saves lives T2 - Nursing TI - Patient safety. Safe surgery initiative saves lives UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105421681&site=ehost-live&scope=site VL - 39 ID - 906 ER - TY - JOUR AB - Attention has turned to issues of surgical patient safety. Essential patient safety practices in the operating room include the application of standard processes of care, the use of protocols and checklists to reduce reliance on memory, the employment of simpler processes as much as possible, the alleviation of conditions that predispose to human error (eg, interruptions, fear, anger, time pressure, anxiety), and the design and use of error-proof devices coupled with frequent training in the use of these devices. These practices can be applied to two issues in surgical patient safety: assurance of correct site surgery and prevention of incidents involving retained foreign bodies. Both of these safety problems involve poor communication between perioperative care personnel and faulty processes of care. Recommendations to ensure that the correct procedure is performed on the correct patient at the correct site have been mandated by the JACHO Universal Protocol. The protocol mandates using a preoperative verification process, marking the operative site, and taking a "time out" immediately before starting the procedure. All health care facilities where invasive procedures that expose patients to harm are performed are required to comply with this protocol. Recommendations to prevent the retention of sponges, sharps, instruments, and other miscellaneous items include consistent application and adherence to standardized counting procedures, performance of a methodical wound exploration before closure of the surgical site, use of radiograph-detectable items in the surgical wound, maintenance of an optimal operating room environment to allow focused performance of operative tasks, and application of radiographs or other technology as indicated to ensure there is no item left by mistake in the operative field. All perioperative care personnel can work together to ensure that these events never happen. Getting to zero is possible. AD - V.C. Gibbs, Department of Surgery QI Program, University of California at San Francisco, Box 0617, 533 Parnassus Avenue U-157, San Francisco, CA 94143-0617, United States AU - Gibbs, V. C. DB - Embase Medline DO - 10.1016/j.suc.2005.09.007 IS - 6 KW - accreditation foreign body general surgery human medical error medical device medical practice medical record neurosurgery operating room orthopedic surgery patient care policy priority journal quality control review risk assessment standardization surgical technique urologic surgery LA - English M3 - Review N1 - L41744046 2006-01-11 PY - 2005 SN - 0039-6109 SP - 1307-1319 ST - Patient safety practices in the operating room: Correct-site surgery and nothing left behind T2 - Surgical Clinics of North America TI - Patient safety practices in the operating room: Correct-site surgery and nothing left behind UR - https://www.embase.com/search/results?subaction=viewrecord&id=L41744046&from=export http://dx.doi.org/10.1016/j.suc.2005.09.007 VL - 85 ID - 624 ER - TY - JOUR AD - Director of Nursing Research, Dartmouth-Hitchcock Medical Center, Lebanon, NH AN - 106884455. Language: English. Entry Date: 20031114. Revision Date: 20150818. Publication Type: Journal Article. Journal Subset: Core Nursing AU - Beyea, S. C. DB - ccm DP - EBSCOhost IS - 2 KW - Foreign Bodies -- Prevention and Control Surgical Count Procedure Treatment Errors -- Prevention and Control AORN -- Standards Human Error Perioperative Nursing -- Standards N1 - Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PMID: NLM12940428. PY - 2003 SN - 0001-2092 SP - 290-294 ST - Patient safety first. Counting instruments and sponges T2 - AORN Journal TI - Patient safety first. Counting instruments and sponges UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106884455&site=ehost-live&scope=site VL - 78 ID - 888 ER - TY - JOUR AD - Perioperative Regional Educator, Franciscan Health Group, Tacoma, WA AN - 106367660. Language: English. Entry Date: 20061201. Revision Date: 20150818. Publication Type: Journal Article. Journal Subset: Core Nursing AU - Watson, D. S. DB - ccm DP - EBSCOhost IS - 2 KW - Health Care Errors -- Prevention and Control Retained Instruments -- Prevention and Control Surgical Count Procedure Accountability Hospital Policies Operating Room Personnel Operating Rooms -- Administration Retained Instruments -- Risk Factors N1 - Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PMID: NLM16927590. PY - 2006 SN - 0001-2092 SP - 273-275 ST - Patient safety first. Counting for patient safety T2 - AORN Journal TI - Patient safety first. Counting for patient safety UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106367660&site=ehost-live&scope=site VL - 84 ID - 816 ER - TY - JOUR AN - 16128316 AU - Dalton, A. DA - Jul DP - NLM ET - 2005/09/01 IS - 7 KW - Foreign Bodies/diagnostic imaging/*prevention & control Humans Medical Errors/*prevention & control Radiography Safety Management/*methods Surgical Instruments/statistics & numerical data Surgical Procedures, Operative/*standards Surgical Sponges/statistics & numerical data LA - eng N1 - Dalton, Aaron News United States Hosp Health Netw. 2005 Jul;79(7):32, 34. PY - 2005 SN - 1068-8838 (Print) 1068-8838 SP - 32, 34 ST - Patient care. The right count T2 - Hosp Health Netw TI - Patient care. The right count VL - 79 ID - 56 ER - TY - JOUR AB - The article presents a surgical item count, procedure implementation and documentation policy which is utilized at Children's Hospital in Boston, Massachusetts to prevent the retainment of surgical items in patients following surgical procedures. AN - 76912534. Language: English. Entry Date: 20121016. Revision Date: 20190620. Publication Type: Article DB - ccm DP - EBSCOhost IS - 7 KW - Surgical Count Procedure Retained Instruments -- Prevention and Control Patient Safety -- Education Hospital Policies N1 - protocol; tables/charts; teaching materials. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2012 SN - 0190-5066 SP - 1-13 ST - The Patient Care Manual T2 - Same-Day Surgery TI - The Patient Care Manual UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=76912534&site=ehost-live&scope=site VL - 36 ID - 747 ER - TY - JOUR AB - BACKGROUND: Peri-implant soft tissue reactive lesions (I-RLs) may jeopardize implant success and survival. To the best of the authors' knowledge, its pathogenesis is unknown. The objective of this study is to conduct a clinicopathologic and polarized light microscopy (PLM) analysis of 14 new I-RLs and compare them with comparable tooth-associated cases (T-RLs) to better understand I-RL pathogenesis. METHODS: Fifty-eight new cases of I-RL and T-RL were retrieved from the pathology department archives of Rambam Health Care Campus, Haifa, Israel. Retrospective analysis of histopathologic and clinical features was conducted, documented, and then compared for: 1) I-RL (n = 14), 2) peri-implant pyogenic granuloma (I-PG) (n = 5), 3) peri-implant peripheral giant cell granuloma (I-PGCG) (n = 9), 4) T-RL (n = 44), 5) tooth-associated pyogenic granuloma (T-PG) (n = 21), and 6) tooth-associated peripheral giant cell granuloma (T-PGCG) (n = 23). Presence of foreign bodies was assessed using PLM. RESULTS: Foreign bodies were found more commonly in I-RLs (n = 13/14; 93%) when compared with T-RLs (n = 18/44; 41%), which was a statistically significant difference (P = 0.01) with an odds ratio of 7.9. Microscopically, I-PGCG was associated with: 1) lower multinucleated giant cell count (P = 0.04); 2) lower density of mesenchymal cells (P = 0.05); and 3) more diffuse, non-lobulated stromal morphology (P = 0.001). Clinically, I-RLs were found in patients who were older, and all cases were located in the posterior region: mandible (n = 12/14; 86%) and maxilla (n = 2/14; 14%). CONCLUSIONS: In cases of implant failure, implantation of foreign bodies may play a role with subsequent development of I-PG and I-PGCG-like lesions. Clinicians should be aware of this risk so they can implement measures to minimize adverse implant outcomes. AD - Department of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus, Haifa, Israel. Department of Pathology, Rambam Health Care Campus. Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel. Department of Oral and Maxillofacial Surgery, Rambam Health Care Campus. AN - 26832832 AU - Halperin-Sternfeld, M. AU - Sabo, E. AU - Akrish, S. DA - May DO - 10.1902/jop.2016.150482 DP - NLM ET - 2016/02/03 IS - 5 KW - Dental Implants Gingival Diseases/*diagnostic imaging Humans Israel *Microscopy, Polarization Retrospective Studies *Dental implants *foreign-body reaction *granuloma, giant cell *granuloma, pyogenic LA - eng N1 - 1943-3670 Halperin-Sternfeld, Michal Sabo, Edmond Akrish, Sharon Journal Article United States J Periodontol. 2016 May;87(5):502-10. doi: 10.1902/jop.2016.150482. Epub 2016 Feb 1. PY - 2016 SN - 0022-3492 SP - 502-10 ST - The Pathogenesis of Implant-Related Reactive Lesions: A Clinical, Histologic and Polarized Light Microscopy Study T2 - J Periodontol TI - The Pathogenesis of Implant-Related Reactive Lesions: A Clinical, Histologic and Polarized Light Microscopy Study VL - 87 ID - 170 ER - TY - JOUR AB - There is abundant evidence that migration of spermatozoa through the female genital tract is not due to sperm mot il it y alone. This study was designed to test the role of peristalsis in the reproductive system of the rat by recording the passage of nonmotile rat and foreign spermatozoa through the uterotubal junction, and the effect of an int r a uterine foreign body on this function. Samples of nonmotile rat, guinea-pig, and human sperms were counted, suspended in Ringer's solution and inseminated into the uterine horns of albino rats after cervical ligation. These comprised 4 groups • the 1st exposed to rat, and the 2nd to foreign spermatozoa, the 3rd with different sperms in each horn, and the 4th after intraluminal insertion of a number 5O silk suture knot. Insemination by laparotomy was done in the estrus phase according to vaginal smears. One to 12 hr. later the oviduct was excised and the contents examined for spermatozoa. Both nonmotile rat and foreign sperms were found to have passed the uterotubal junction, and this occurred as well in some animals in whom the cervix had not been ligated. The presence of the intraluminal foreign body, which has been shown to be a contraceptive in the rat, did not prevent the passage of nonmotile guinea-pig, rat or human sperms into the oviduct. The motility of spermatozoa is not a prerequisite of their passage into the rat oviduct. Sturgis Boston, Mass. (X, 2a,3). AD - S.L. Marcus, Dept. of Obstet. Andgynecol, Cornell Univ. Med. Coll., New York, NY, United States AU - Marcus, S. L. DB - Embase Classic IS - 7 KW - contraceptive agent Ringer solution albinism artificial insemination bullet estrus female genital system foreign body genital system guinea pig horn human laparotomy ligation oviduct peristalsis rat recording silk sperm spermatozoon suture United States uterus uterus horn vagina smear LA - English M3 - Article N1 - L286041634 1965-12-01 PY - 1965 SP - 33-35 ST - THE PASSAGE of RAT and FOREIGN SPERMATOZOA THROUGH THE UTEROTUBAL JUNCTlONOF THE RAT T2 - Amer.J.Obstet. Gynec. TI - THE PASSAGE of RAT and FOREIGN SPERMATOZOA THROUGH THE UTEROTUBAL JUNCTlONOF THE RAT UR - https://www.embase.com/search/results?subaction=viewrecord&id=L286041634&from=export VL - 91 ID - 694 ER - TY - JOUR AB - Background: The aim of this study was to establish whether new prosthetic materials with absorbable components, designed to reduce the amount of foreign material in abdominal wall repair, offer advantages over the conventional polypropylene meshes. Methods: Seven × 5 cm defects created in the anterior abdominal wall of New Zealand white rabbits were repaired by using a nonabsorbable polypropylene prosthesis (Surgipro; Tyco, Barcelona, Spain) or 1 of 2 partially absorbable prostheses available on the market (Vypro II and Ultrapro; Johnson & Johnson, St. Stevens-Woluwe, Belgium). At 14 and 90 days after surgery, tissue/prosthesis specimens were subjected to histological studies, biomechanical strength tests, and shrinkage evaluation. Results: At 90 days, the absorbable filaments of Vypro II had been completely reabsorbed, whereas Ultrapro only showed signs of biodegradation in a few zones. Host tissue infiltration and collagen I deposition in the 3 reticular meshes was optimal. Macrophage counts, mesh shrinkage, and biomechanical resistance values were similar. Conclusions: Partially absorbable prostheses perform as well as the standard polypropylene mesh and have the benefit that less foreign material remains in the recipient, without compromising mechanical resistance. © 2007 Excerpta Medica Inc. All rights reserved. AD - Department of Surgery, Alcalá University, Ctra Madrid-Barcelona, Km 33.600, 28871 Alcala de Henares, Madrid, Spain Department of Medical Specialities, Alcalá University, Ctra Madrid-Barcelona, Km 33.600, 28871 Alcala de Henares, Madrid, Spain AU - Bellón, J. M. AU - Rodríguez, M. AU - García-Honduvilla, N. AU - Pascual, G. AU - Buján, J. DB - Scopus DO - 10.1016/j.amjsurg.2006.11.016 IS - 1 KW - Abdominal wall repair Biomechanical resistance Macrophages Partially absorbable meshes Peritoneum Polypropylene Shrinkage M3 - Article N1 - Cited By :63 Export Date: 10 November 2020 PY - 2007 SP - 68-74 ST - Partially absorbable meshes for hernia repair offer advantages over nonabsorbable meshes T2 - American Journal of Surgery TI - Partially absorbable meshes for hernia repair offer advantages over nonabsorbable meshes UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-34249911987&doi=10.1016%2fj.amjsurg.2006.11.016&partnerID=40&md5=c377f0e59c3bf597733642898606137f VL - 194 ID - 1563 ER - TY - CHAP AB - Acute paronychia is one of the most common infections of the hand. It is usually caused by a breakdown of the seal between the nail plate and the nail fold with infection resulting from subsequent inoculation of bacterial or fungal pathogens. This is typically precipitated by nail-biting, trauma, manicures, ingrown nails, and hangnail manipulation. Abscess involving pus within the soft tissues adjacent to the nail may occur, indicating the need for surgical drainage. From a microbiology perspective, paronychia of the hand is reported to be a polymicrobial infection with mixed aerobic and anaerobic bacterial flora in around 50% of cases. The most common infective pathogen is Staphylococcus aureus (including methicillin-resistant Staphylococcus aureus (MRSA)), but other aerobic bacteria may include Streptococcus species or gram-negative bacteria. While anaerobic flora such as Bacteroides, Enterococcus species, or Eikenella corrodens are associated with exposure to oral secretions through nail-biting and digital sucking practices (more common in children). Clinical history and local antibiotic guidance, including consideration of MRSA rates, should direct prescription of antibiotics. Non-bacterial infections are less common but may include fungal infections such as Candida albicans and viral infections such as herpes simplex. If a paronychia has been present for less than six weeks, it is classified as acute, whereas those present for six weeks or more are classified as chronic. Chronic paronychia is a multifactorial inflammatory condition primarily caused by exposure to environmental allergens or irritants. The disruption to the protective barrier caused by this inflammatory process may result in colonization with bacterial or fungal organisms, for which Candida albicans is the most commonly implicated micro-organism. With differing etiologies and treatment approaches, chronic paronychia should be considered a separate entity to acute paronychia, which is the focus of this article. Another important differential diagnosis is herpetic whitlow, a herpes simplex virus infection that may manifest clinically with the presence of blisters involving the distal phalanx. Surgical drainage is contraindicated unless a concurrent bacterial infection is present. Paronychia involving toes is a relatively common condition and may be associated with ingrowing toenails. Although treatment approaches may be similar, the focus of this article is the management of acute paronychia drainage of the hand. Clinical Assessment and Diagnosis Acute paronychia is diagnosed clinically with the presence of pain, swelling, and erythema of the nail folds. Formation of pus along the paronychial fold may occur; if untreated, an abscess may progress to involve the eponychium and under the nail plate. This can generally be identified by the presence of a tender, boggy swelling. The digital pressure test, as described by Turkmen et al., can also be used to evaluate for the presence of pus within the soft tissue. If light pressure is applied to the volar aspect of the tip of the affected digit, a localized region of skin blanching around the nail may indicate the presence of an underlying abscess. Furthermore, if pus is deep to the nail plate, it may be visible on inspection and ballotable on palpation. A felon is an infection in the pulp of the distal phalanx of a digit and is a separate condition to paronychia. Although a paronychia can lead to the development of a felon, the presence of one does not indicate the presence of the other. Careful examination of the digit should be performed to identify the clinical presence of a felon and thus the need for surgical drainage. This is characterized by a tender, fluctuant, swelling involving the pulp of the digit. This article will only discuss acute paronychia drainage. In the early stage of paronychia, inflammation of the paronychial fold alone may be present, without pus formation. The majority of such cases may be managed non-operatively in the primary care or emergency department setting. Treatment involving oral antibiotics with close monitoring comprising follow-up appointments and patient safety advice is recommended. Oral antibiotics with gram-positive coverage are advised, or if suspecting exposure to oral bacteria, a broad-spectrum agent is preferable. Although some authors recommend the use of antiseptic or warm water soaks, we find no clear evidence to recommend their use routinely in any stage of the condition. In the later stage of paronychia, the presence of pus in the form of a local abscess may be present. Laboratory and radiological investigations are important in this stage. Plain film radiographs of the involved digit are used to investigate for the presence of associated foreign bodies, fractures, or osteomyelitis. Glucose testing is important to review glycaemic control in diabetics and may occasionally identify undiagnosed diabetes. Extended laboratory blood tests such as full blood count and inflammatory markers are generally only indicated in more severe cases where marked cellulitis or tracking lymphangitis is present. In all cases of paronychia with abscesses, surgical drainage is indicated. This may be performed in primary care or emergency department settings depending on local resources and expertise. Referral to tertiary hand surgery may otherwise be required. AD - St George's Hospital London St George’s Hospital AN - 32644572 AU - Macneal, P. AU - Milroy, C. CY - Treasure Island (FL) LA - eng N1 - Macneal, Peter Milroy, Catherine Review Book Chapter NBK559146 [bookaccession] PB - StatPearls Publishing Copyright © 2020, StatPearls Publishing LLC. PY - 2020 ST - Paronychia Drainage T2 - StatPearls TI - Paronychia Drainage ID - 252 ER - TY - JOUR AB - OBJECTIVE: Paraspinal textiloma (ParaTex) is a well-known complication after posterior lumbar surgery. However, there are few articles on this topic, probably because of medicolegal concerns. In addition, patients with ParaTex can remain asymptomatic for months or even years unless it causes complications. The purpose of this study is to review our experience on this "undesirable" topic to increase awareness among spinal surgeons and radiologists and avoid unnecessary morbidity, which is still being encountered. METHODS: This study is a retrospective case series of six patients with ParaTex who underwent posterior lumbar spinal surgery in our neurosurgical department between January 2000 and December 2010. The medical records of each patient were reviewed and demographic data, clinical characteristics, initial diagnosis, surgical procedures, time interval between operation and onset of symptoms, biological and radiologic findings, treatment, and outcome were analyzed. RESULTS: The six patients included four women and two men with a mean age of 48 years. Four patients had a history of lumbar disc herniation, one had undergone a laminectomy for a lumbar spinal stenosis, and a Gill's procedure was performed in one patient with a lumbar spondylolisthesis. The time from the causative operation to presentation ranged from 2 months to 6 years. All patients presented with nonspecific lower back pain and/or surgical site infection without fever or neurological symptoms. Laboratory parameters showed increased blood sedimentation rates and/or C-reactive protein level in four patients. Bacteria were isolated in only one patient. Five patients were evaluated with computed tomography scan, and this showed the spongiform pattern with gas bubbles in three cases. Magnetic resonance imaging was performed in two patients. The signal intensity varies according to stage and fluid content of the lesion. The ParaTex was removed surgically in all patients with a good outcome. CONCLUSIONS: ParaTexs are more common in obese patients, after emergency surgery, and with unplanned changes in surgical procedure. On computed tomography scan, the classic spongiform appearance is highly suggestive. Magnetic resonance imaging findings are variable and less specific, but confrontation of imaging data with the surgical history helps with the preoperative diagnosis. In the early postoperative period symptoms are related to the exudative response; at later times symptoms may be linked to pseudotumor formation clinically and radiologically. Appropriate antibiotic therapy is recommended when a septic complication is present or suspected. Strict measures must be taken to prevent this complication. Surgical sponges should always be counted at least three times (preoperatively, at closure, and at the end), radiopaque markers should be used, and if there is doubt, intraoperative radiography must be performed. AD - Department of Neurosurgery, Mohammed V Military Teaching Hospital, University of Mohammed V Souissi, Rabat, Morocco. akhaddar@hotmail.fr AN - 22120328 AU - Akhaddar, A. AU - Boulahroud, O. AU - Naama, O. AU - Al-Bouzidi, A. AU - Boucetta, M. DA - Feb DO - 10.1016/j.wneu.2011.07.017 DP - NLM ET - 2011/11/29 IS - 2 KW - Adult Anti-Bacterial Agents/therapeutic use C-Reactive Protein Female Granuloma, Foreign-Body/pathology/surgery Humans Intervertebral Disc Displacement/surgery Laminectomy Low Back Pain/surgery Lumbosacral Region/*surgery Magnetic Resonance Imaging Male Middle Aged Neurosurgical Procedures/*adverse effects Postoperative Complications/diagnostic imaging/*etiology/prevention & control Retrospective Studies Spinal Stenosis/surgery Spine/*surgery Spondylolisthesis/surgery Surgical Sponges/*adverse effects Surgical Wound Infection/drug therapy/microbiology Tomography, X-Ray Computed LA - eng N1 - 1878-8769 Akhaddar, Ali Boulahroud, Omar Naama, Okacha Al-Bouzidi, Abderrahmane Boucetta, Mohamed Journal Article United States World Neurosurg. 2012 Feb;77(2):375-80. doi: 10.1016/j.wneu.2011.07.017. Epub 2011 Nov 7. PY - 2012 SN - 1878-8750 SP - 375-80 ST - Paraspinal textiloma after posterior lumbar surgery: a wolf in sheep's clothing T2 - World Neurosurg TI - Paraspinal textiloma after posterior lumbar surgery: a wolf in sheep's clothing VL - 77 ID - 118 ER - TY - JOUR AB - Even if gossypibomas are extremely rare in the Oro-Maxillofacial region, they should be evoked in bizarre tumors when repeated histology tests are not contributive, especially in patients with a history of dento-sinusal surgery. As it is recommended in general surgery, gauzes should be carefully counted when used in dentistry. AD - Oral and Maxillofacial Surgeon Al Farabi Hospital Oujda Morocco. Medical Oncologist Hassan II Oncology Center Oujda Morocco. AN - 29375841 AU - Guerrouani, A. AU - Kairouani, M. C2 - PMC5771908 DA - Jan DO - 10.1002/ccr3.1273 DP - NLM ET - 2018/01/30 IS - 1 KW - *Foreign bodies *foreign body reaction *gossypiboma *hard palate *paranasal sinus *reconstructive surgical procedures LA - eng N1 - 2050-0904 Guerrouani, Alae Orcid: 0000-0001-7144-7852 Kairouani, Mouna Case Reports Clin Case Rep. 2017 Nov 27;6(1):71-77. doi: 10.1002/ccr3.1273. eCollection 2018 Jan. PY - 2018 SN - 2050-0904 (Print) 2050-0904 SP - 71-77 ST - Paranasal gossypiboma mimicking an aggressive tumor: a case report T2 - Clin Case Rep TI - Paranasal gossypiboma mimicking an aggressive tumor: a case report VL - 6 ID - 207 ER - TY - JOUR AD - Gastroenterology Departament, Centro Hospitalar do Algarve, EPE, Portugal AU - Antunes, A. G. AU - Peixe, B. AU - Guerreiro, H. DB - Scopus DO - 10.1016/j.gastrohep.2016.08.007 IS - 9 M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2017 SP - 615-617 ST - Pancreatitis y colangitis secundaria a la migración intraductal de un clip de metal 5 años después de una colecistectomía laparoscópica T2 - Gastroenterologia y Hepatologia TI - Pancreatitis and cholangitis following intraductal migration of a metal clip 5 years after laparoscopic cholecystectomy UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85008675501&doi=10.1016%2fj.gastrohep.2016.08.007&partnerID=40&md5=6eaddb3f725d75ea49a510492d68e331 VL - 40 ID - 1113 ER - TY - JOUR AB - LEARNING OBJECTIVE #1: Identify Streptococcus Aginosus as an emerging cause of pyogenic liver and pancreatic abscesses. . LEARNING OBJECTIVE #2: Recognize that uncontrolled DM is a risk factor for pancreatic and hepatic abscesses. CASE: A 72 year old man presented with 6 months of progressively worsening lethargy and epigastric discomfort. He had a history of DM and an episode of acute pancreatitis 2 years prior. On presentation, he was febrile and had diffuse abdominal tenderness. He had a white count of 14,700. His liver function tests and pancreatic enzymes were normal. His hemoglobin A1C was 8.8 %. A CT scan of the abdomen revealed a 3.5 cm necrotic mass in the uncinate process and numerous hepatic masses. Blood culture grew Streptococcus Aginosus. EUS guided FNA of the pancreatic mass and a CT guided FNA of a sentinel hepatic lesion revealed inflammatory cells and was negative for malignant cells. The patient received 4 weeks of IV antibiotics and was discharged on a 2 week course of oral antibiotics. Three months later, a repeat CT scan revealed complete resolution of the pancreatic and hepatic lesions. DISCUSSION: A suspicious abdominal mass on imaging is a common finding encountered by the internist. As illustrated in our case, pyogenic intra-abdominal abscesses can present as mass lesions with vague symptoms and laboratory investigation results. The liver is the most common site for pyogenic intra-abdominal abscesses with a prevalence rate of 8-16 cases per 100,000 among hospitalized patients and an estimated 2.3 cases per 100,000 in the population. Pancreatic abscesses are rare but are associated with greater mortality. The underlying mechanisms of pancreatic and liver abscess formation are variable. In the liver, about 60% of abscesses can be attributed to biliary tract obstruction. Other frequent causes of liver abscess include infections of the portal bed infections and direct extension from local infections. Most cases of pancreatic abscess occur following an episode of acute pancreatitis and infection of a pancreatic cyst. Penetrating abdominal trauma, surgery and bowel perforation due to foreign body, inflammatory bowel disease and ischemic colitis have been implicated in both pancreatic and liver abscesses, but are less common. Escherichia Coli is the most frequently identified pathogen from intraabdominal abscesses. Among gram positives, Streptococcus Millieri is an important cause of pyogenic bacterial abscess. This group of bacteria is present in 12 % of liver abscesses and has been identified in up to 20-40 % of isolates from healthy appendices. Streptococcus Millieri are also known as the streptococcus Aginosus group after the most commonly encountered bacteria in the group. Streptococcus Aginosus has been found in 64 % of isolates from healthy individuals containing streptococcus Millieri species. Streptococcus Aginosus also has the highest predilection to cause intra-abdominal abscess formation. The other members of this group are Streptococcus Intermedius and Streptococcus Constellatus. All members of this group are normal flora, found in the oral cavity, the GI and the GU tracts. Infectious abscesses due to these organisms usually occur in patients with cancer and impaired immunity or following surgery and abdominal trauma Diabetes Mellitus is also a risk factor for infectious abscesses, particularly in the liver. Patients with DM can have a 3.6 fold increased risk of developing pyogenic liver abscesses. This risk is attributable to the hyperglycemic environment in DM which leads to neutrophil dysfunction and promotes the growth of pathogenic bacteria. Patients with DM have decreased chemo taxis, phagocytosis and oxidative action of phagocytes. Other features of inflammation such as protein leakage and edema formation in response to inflammatory mediators are also impaired in diabetic patients. One mechanism for neutrophilic dysfunction in hyperglycemia is thought to be the result of accumulation of advanced glycation end products. (AGEs), formed due to the interaction of glucose with prot ins and lipids. Advanced glycation products modify several receptors on endothelial cells, smooth cells and mononuclear phagocytes, altering membrane structure and function. The interaction between AGEs and phagocyte cell membranes leads to decreased fluidity and leukocyte migration. Hyperglycemia also causes increased levels of sorbitol in phagocytic cells via activation of the polyol pathway which further impairs leukocyte and endothelial cell interactions. The mechanisms leading to neutrophilic dysfunction are related to the degree of hyperglycemia and can be reversed with improved glycemic control. In our patient, his uncontrolled DM was a likely predisposing factor for his liver and pancreatic abscesses. Good glycemic control can thus prevent intraabdominal infections and complement antibiotic therapy. Streptococcus Aginosus is sensitive to commonly used antibiotics but there is data suggesting emerging resistance to antibiotics which could pose a significant problem in the management of infections caused by this organism. Further studies are warranted to better understand resistance patterns and guide antibiotic therapy. AD - N.A. Bulcha, Montefiore Medical Center, Bronx, NY, United States AU - Bulcha, N. A. AU - Khanapara, D. B. AU - Slinchenkova, O. DB - Embase IS - 2 KW - antibiotic agent protein glucose receptor hemoglobin pancreas enzyme advanced glycation end product lipid sorbitol polyol diabetic patient human society internal medicine liver abscess Streptococcus liver patient infection pancreas abscess abscess abdominal abscess hyperglycemia phagocyte bacterium liver injury glycemic control risk computer assisted tomography endothelium cell acute pancreatitis risk factor antibiotic therapy pancreas cyst blood culture mortality epigastric discomfort population inflammation phagocytosis tax cholestasis glycation hospital patient abdominal penetrating trauma prevalence neutrophil pyogenic liver abscess diabetes mellitus laboratory abdomen lethargy abdominal injury surgery neoplasm flora internist Streptococcus intermedius imaging species Streptococcus constellatus mouth cavity pathogenesis immunity abdominal mass liver function test Escherichia coli environment ischemic colitis abdominal infection cancer cell edema inflammatory bowel disease leukocyte inflammatory cell foreign body intestine perforation mononuclear phagocyte leukocyte migration cell membrane cell interaction membrane structure traumatology disease predisposition organisms abdominal tenderness male LA - English M3 - Conference Abstract N1 - L72289283 2016-05-31 PY - 2016 SN - 1525-1497 SP - S699-S700 ST - Pancreatic and hepatic abscesses in a diabetic patient simulating a malignancy T2 - Journal of General Internal Medicine TI - Pancreatic and hepatic abscesses in a diabetic patient simulating a malignancy UR - https://www.embase.com/search/results?subaction=viewrecord&id=L72289283&from=export VL - 31 ID - 404 ER - TY - JOUR AB - Palmar-plantar fibromatosis, the most common type of fibromatosis, is well recognized in the adult population, but many clinicians and pathologists are unfamiliar with the fact that children may also be affected by this process. This report describes the clinicopathologic findings in 56 cases of palmar-plantar fibromatosis in children and preadolescents. Our study group included 19 males and 37 females, ranging from 2 to 12 years of age at the time of their first surgical procedure (median age, 9 years). The patients typically presented with solitary, lobular or multilobular masses in the 0.5- to 2.5-cm size range. The preoperative duration of the lesions ranged from 1 month to 6 years, with 1 patient purportedly having clinical evidence of disease since birth. All but two of the initial lesions occurred on the plantar aspect of the feet, typically in the region of the arch. Only 2 patients presented with palmar disease. The tumors were usually painless, except when pressure was applied. Seven patients had a history of trauma, sometimes involving a foreign body. One patient presented with concurrent disease involving both feet, and 12 additional patients subsequently developed palmar-plantar fibromatosis in another extremity, knuckle pads on the hands, or had other clinical findings linked to this disease. A family history was available for 25 patients, and 11 individuals had relatives with palmar-plantar fibromatosis, and 4 others had relatives with a history that was either suspicious for palmar-plantar disease or positive for other disorders associated with this disease. Histologically, the tumors involved aponeurosis and commonly formed discontinuous, moderately cellular, nodular masses composed of spindled cells with intervening collagen. Mitotic counts for 79 separately submitted tumor specimens ranged from 0 to 31 mitotic figures per 25 wide-field high power fields (mean mitotic count, 3.4 mitotic figures per 25 wide-field high power fields). Eight tumor had > or =10 mitoses per 25 wide-field high power fields. All patients were initially managed by local excision, and in most of cases, histologic examination showed tumor extending to the tissue edge. Thirty-two of 38 patients (84.2%) with clinical follow-up, ranging from 4 months to 33 years (mean, 14 years 9 months; median, 16 years 1 month), had one (n = 16) or more (n = 16) local recurrence of their fibromatosis. AD - Department of Soft Tissue Pathology, Armed Forces Institute of Pathology, Washington, DC 20306, USA. FETSCH@afip.osd.mil AN - 16006806 AU - Fetsch, J. F. AU - Laskin, W. B. AU - Miettinen, M. DA - Aug DP - NLM ET - 2005/07/12 IS - 8 KW - Child Child, Preschool Female Fibroma/*pathology Foot Diseases/*pathology *Hand Humans Male Soft Tissue Neoplasms/*pathology LA - eng N1 - Fetsch, John F Laskin, William B Miettinen, Markku Journal Article United States Am J Surg Pathol. 2005 Aug;29(8):1095-105. PY - 2005 SN - 0147-5185 (Print) 0147-5185 SP - 1095-105 ST - Palmar-plantar fibromatosis in children and preadolescents: a clinicopathologic study of 56 cases with newly recognized demographics and extended follow-up information T2 - Am J Surg Pathol TI - Palmar-plantar fibromatosis in children and preadolescents: a clinicopathologic study of 56 cases with newly recognized demographics and extended follow-up information VL - 29 ID - 55 ER - TY - JOUR AB - The article discusses a paper presentation on developing a communication system for the surgical patients who required abdominal packing and transfer to a surgical trauma intensive unit for stabilization. It is suggested that when a patient has damage control surgery, a pink bracelet should be applied to alert the Intensive Care Unit (ICU) bedside nurse. Also discussed is the development of the packing log process to prevent retained sponges following damage control surgery. AD - MSN, RNC, Women's & Children's Services, Christiana Care Health Services, Newark, DE. AN - 62057998. Language: English. Entry Date: 20110901. Revision Date: 20111027. Publication Type: Article AU - Skinner, Nancy DB - ccm DO - 10.1111/j.1552-6909.2010.01119_27.x DP - EBSCOhost KW - Obstetric Emergencies -- Surgery Critical Care Surgical Count Procedure Intensive Care Units Female Pregnancy N1 - abstract. Supplement Title: Sep2010 Supplement 1. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. NLM UID: 8503123. PY - 2010 SN - 0884-2175 SP - S39-S40 ST - Packed and Wearing Pink: Damage Control Surgery in the Obstetric Operating Room T2 - JOGNN: Journal of Obstetric, Gynecologic & Neonatal Nursing TI - Packed and Wearing Pink: Damage Control Surgery in the Obstetric Operating Room UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=62057998&site=ehost-live&scope=site VL - 39 ID - 903 ER - TY - JOUR AB - BACKGROUND: Barriers placed intraabdominally may aid in hemostasis and help prevent adhesion formation. CASE: A 17-year-old woman presented with acute pelvic pain and a complex pelvic mass. A laparotomy was performed. To ensure hemostasis, Surgicel (Johnson & Johnson Medical, Arlington, Texas) was placed, and Seprafilm (Genzyme Corp., Cambridge, Massachusetts) was used for adhesion prevention. Within the first postoperative day the patient's status deteriorated, with increasing pain and significant pyrexia. Computed tomography was highly suspicious for a bowel injury. Repeat laparotomy found no injury.the Surgicel was removed and the abdomen irrigated. The remaining postoperative course was uneventful. CONCLUSION: Seprafilm has been associated with acute reactions, and Surgicel has mimicked many radiologic abnormalities. It is imperative to inform the radiologist of the intraoperative use of these agents to allow use of a proper imaging modality in the postoperative period ana to avoid unnecessary repeat surgeries. © Journal of Reproductive Medicine®, Inc. AD - Departments of Obstetrics and Gynecology, Albert Einstein Medical Center, Temple University Hospital, Philadelphia, PA, United States Department of Obstetrics and Gynecology, Temple University Hospital, Philadelphia, PA 19140, United States AU - Jaspan, D. AU - Dandolu, V. AU - Miller, M. AU - Dunton, C. DB - Scopus IS - 12 KW - Cellulose Oxidized Postoperative complications M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2007 SP - 1109-1110 ST - Oxidized regenerated cellulose presenting as a postoperative cyst: A case report T2 - Journal of Reproductive Medicine for the Obstetrician and Gynecologist TI - Oxidized regenerated cellulose presenting as a postoperative cyst: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-39549087015&partnerID=40&md5=f6be1d108f7942ee2bbf0f863fe9818b VL - 52 ID - 1548 ER - TY - JOUR AB - Purpose: To report the outcomes of retinal detachment (RD) repair following recent scleral laceration repair. Methods: This retrospective, observational, consecutive case series consisted of patients who underwent RD repair for a retinal detachment that was diagnosed within two weeks of scleral laceration repair at our institution between January 1, 2007 and June 8, 2013. Patients with less than 5 months of follow-up and those with intraocular foreign bodies were excluded. Results: Twenty patients met inclusion criteria. Five of these cases were deemed inoperable at the time of retina surgery. Among the 15 who had successful primary RD repair, the average follow-up was 23 months (range 5-52). Six had redetachments requiring additional surgery. The average number of surgeries for RD in this group was 1.6 (range 1-4). At the last visit, 10 of 15 were still attached . The final visual acuities were as follows: better than counting fingers in 3, counting fingers in 5, hand motions in 5, light perception in 1, and no light perception in 1. None of the patients were known to have undergone enucleation or evisceration. No cases of sympathetic ophthalmia developed. Conclusions: Retinal detachment after scleral laceration carries a grave prognosis, but preservation of the eye was common and attempted repair gave ambulatory vision in over half of patients. AD - D.C. Reed, Wills Eye Hospital, Philadelphia, PA, United States AU - Reed, D. C. AU - Juhn, A. AU - Rayess, N. AU - Hsu, J. AU - Chiang, A. DB - Embase IS - 13 KW - case study clinical article complication diagnosis evisceration female finger follow up human intraocular foreign body laceration male motion prognosis retina detachment surgery sclera surgery sympathetic ophthalmia vision visual acuity LA - English M3 - Conference Abstract N1 - L616118848 2017-05-16 PY - 2014 SN - 0146-0404 SP - 1112 ST - Outcomes of retinal detachment repair after scleral laceration T2 - Investigative Ophthalmology and Visual Science TI - Outcomes of retinal detachment repair after scleral laceration UR - https://www.embase.com/search/results?subaction=viewrecord&id=L616118848&from=export VL - 55 ID - 446 ER - TY - JOUR AB - PURPOSE: To report outcomes of retinal detachment (RD) repair following posterior open globe injury. METHODS: This retrospective, consecutive case series examined patients who underwent RD repair following Zone II and/or III open globe injury repair between January 1, 2007 and October 31, 2013. Patients with <3 months of follow-up since their last vitreoretinal surgery, and those who underwent pars plana vitrectomy (e.g., for intraocular foreign body) during their initial open globe injury repair were excluded. RESULTS: Of 30 patients who met inclusion criteria, reattachment of the retina was achieved in 25 (83%) during the first vitreoretinal surgical procedure and 5 (17%) were deemed inoperable intraoperatively. Ten patients (30%) developed recurrent RD, and 8 underwent additional surgery. At last follow-up, reattachment was observed in 4 of these 8. The overall rate of final reattachment was 63% (19 patients). The mean number of surgeries for RD was 1.5 (range, 1-3). Fifteen patients (50%) achieved final visual acuity of counting fingers or better. Mean follow-up from the last vitreoretinal surgery was 23 months (range, 3-52). CONCLUSION: Although RD following posterior open globe injury confers a grave prognosis, successful anatomic reattachment of the retina was achieved in the majority of patients in this series, with half achieving ambulatory vision. AD - *The Retina Service of Wills Eye Hospital, Philadelphia, Pennsylvania; and †Mid Atlantic Retina, Plymouth Meeting, Pennsylvania. AN - 26383708 AU - Reed, D. C. AU - Juhn, A. T. AU - Rayess, N. AU - Hsu, J. AU - Chiang, A. DA - Apr DO - 10.1097/iae.0000000000000772 DP - NLM ET - 2015/09/19 IS - 4 KW - Adolescent Adult Aged Aged, 80 and over Child Child, Preschool Endotamponade Eye Foreign Bodies/etiology/physiopathology/*surgery Eye Injuries, Penetrating/etiology/physiopathology/*surgery Female Humans Male Middle Aged Retina/*injuries/physiopathology Retinal Detachment/etiology/physiopathology/*surgery Retrospective Studies Scleral Buckling Silicone Oils/administration & dosage Visual Acuity/physiology Vitrectomy Vitreoretinal Surgery LA - eng N1 - 1539-2864 Reed, David C Juhn, Alexander T Rayess, Nadim Hsu, Jason Chiang, Allen Journal Article United States Retina. 2016 Apr;36(4):758-63. doi: 10.1097/IAE.0000000000000772. PY - 2016 SN - 0275-004x SP - 758-63 ST - OUTCOMES OF RETINAL DETACHMENT REPAIR AFTER POSTERIOR OPEN GLOBE INJURY T2 - Retina TI - OUTCOMES OF RETINAL DETACHMENT REPAIR AFTER POSTERIOR OPEN GLOBE INJURY VL - 36 ID - 166 ER - TY - JOUR AB - Recounted are some, not all, of the most significant contributions to otology. The history of otology has, for the most part, followed the history of medicine: Little was known of otology by the ancient physicians, but their work must be reviewed to appreciate the progress that has been made. Most of the otology produced during the Middle Ages was limited to those structures that were readily accessible; otologic surgery was confined to trauma and removal of foreign bodies from the external auditory canals. Examination of the ear began after studies of the ear by Italian anatomists during the seventeenth century. It was not until the end of the eighteenth century that magnification was used so that the minute anatomic details could be observed. The clinical specialty of otology started in France (1850s), emerged as a scientific specialty in England, and received explosive progress from the German-speaking countries at the end of the nineteenth century. Otology has a remarkable background. AN - 8637729 AU - Pappas, D. G. DA - Feb DO - 10.1016/s0194-5998(96)70162-6 DP - NLM ET - 1996/02/01 IS - 2 KW - Ear/anatomy & histology/injuries/surgery Ear Diseases/history Europe Foreign Bodies/history/surgery History, 16th Century History, 17th Century History, 18th Century History, 19th Century History, 20th Century History, Ancient History, Medieval Humans Otolaryngology/*history LA - eng N1 - Pappas, D G Historical Article Journal Article Portrait England Otolaryngol Head Neck Surg. 1996 Feb;114(2):173-96. doi: 10.1016/s0194-5998(96)70162-6. PY - 1996 SN - 0194-5998 (Print) 0194-5998 SP - 173-96 ST - Otology through the ages T2 - Otolaryngol Head Neck Surg TI - Otology through the ages VL - 114 ID - 23 ER - TY - JOUR AB - A 34-year-old previously healthy Hispanic male presented to the emergency room complaining of progressive left upper eyelid swelling and pain for more than 2 weeks. He was previously diagnosed and treated for a "pink eye" but failed to improve. He reported a previous "bug bite" around the left lateral canthus a few weeks prior to admission. Computer tomography orbit with contrast showed left exophthalmos, an enhancing left lacrimal gland and orbital inflammatory signs suggestive of possible intraorbital abscess. Intravenous antibiotics did not improve his symptoms. Surgical debridement showed no abscess but inflamed soft tissues and lacrimal gland. Intravenous steroids failed to improve his symptoms. On postoperative day 3, the patient reported that an insect had "jumped" out from his left orbit. Identification of the specimen proved to be a mature flea. Biopsy of the lacrimal gland showed degranulation of eosinophils and foreign body material consistent with probable insect leg parts. Copyright © 2018 The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc. AD - Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, 6560 Fannin Street, Houston, TX 77030, United States Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, United States Department of Ophthalmology, Baylor College of Medicine, Houston, TX, United States Departments of Pathology and Laboratory Medicine and Ophthalmology, Weill Cornell Medicine, New York, NY, United States Department of Pathology, UT MD Anderson Cancer Center, Houston, TX, United States Departments of Ophthalmology and Visual Sciences, University of Texas Medical Branch (UTMB), Galveston, TX, United States Departments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medicine, New York, NY, United States AU - Prospero Ponce, C. M. AU - Malik, A. I. AU - Vickers, A. AU - Chevez-Barrios, P. AU - Lee, A. G. DB - Scopus DO - 10.1097/IOP.0000000000001115 IS - 4 M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 SP - E115-E118 ST - Orbital Inflammatory Syndrome Secondary to Flea Bite T2 - Ophthalmic Plastic and Reconstructive Surgery TI - Orbital Inflammatory Syndrome Secondary to Flea Bite UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85051060510&doi=10.1097%2fIOP.0000000000001115&partnerID=40&md5=17ae76c84071e0bdaf3be57df1f3ba6f VL - 34 ID - 1071 ER - TY - JOUR AB - Purpose: Ocular compartment syndrome (OCS) is a rare ocular emergency where urgent surgical treatment is required to avoid irreversible visual loss. We describe the clinical presentation and management for patients presenting to our centre with OCS. Methods: Single centre, retrospective case series. We included patients with a diagnosis of OCS that presented to the Royal Adelaide Hospital from 2004 to 2011. We reviewed the clinical features, imaging and timing of intervention from their clinical records. Results: 9 patients were included. 5/9 of our patient had preceding trauma, while other etiologies included post-operative cellulitis, foreign body, prolonged prone position during surgery, and cavernous sinus thrombosis. All had acute, painful decrease in visual acuity. Common examination findings included proptosis, relative afferent papillary defect, periorbital oedema, ophthalmoparesis and chemosis. Globe tenting was evident on radiological imaging for 6/9 cases. All the patients underwent surgical decompression. Three patients had visual recovery of more than 3 lines of Snellen acuity after having decompression less than two hours after onset of symptoms. The remaining patients had minimal visual recovery, with postoperative visual acuities ranging from count fingers to no perception to light. Conclusion: Delayed decompression more than two hours after the onset of OCS leads to irreversible visual loss. All patients presenting with history and examination findings suggestive of OCS should undergo emergency canthotomy and cantholysis prior to any additional investigations to minimize visual loss. AD - M. Sun, SA Institute of Ophthalmology, Royal Adelaide Hospital, Adelaide, Australia AU - Sun, M. AU - Chan, W. O. AU - Selva, D. DB - Embase DO - 10.1111/j.1442-9071.2011.02689.x KW - orbit compartment syndrome case study New Zealand college human patient visual impairment surgery visual acuity emergency imaging decompression examination clinical feature cavernous sinus thrombosis hospital diagnosis body position foreign body cellulitis ophthalmoplegia etiology periorbital edema chemosis decompression surgery exophthalmos injury LA - English M3 - Conference Abstract N1 - L70831754 2012-08-20 PY - 2011 SN - 1442-6404 SP - 21 ST - Orbital compartment syndrome: A case series T2 - Clinical and Experimental Ophthalmology TI - Orbital compartment syndrome: A case series UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70831754&from=export http://dx.doi.org/10.1111/j.1442-9071.2011.02689.x VL - 39 ID - 532 ER - TY - JOUR AD - Professor, University of Wisconsin, Milwaukee School of Nursing AN - 107073556. Language: English. Entry Date: 20011207. Revision Date: 20150818. Publication Type: Journal Article AU - Murphy, E. K. DB - ccm DO - 10.1016/S0001-2092(06)61686-4 DP - EBSCOhost IS - 4 KW - Foreign Bodies -- Complications Surgical Sponges Perioperative Nursing -- Legislation and Jurisprudence Negligence -- Legislation and Jurisprudence -- Wisconsin Surgeons -- Legislation and Jurisprudence -- Wisconsin Wisconsin Surgical Count Procedure N1 - legal case. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Legal Case: Lewis v Physicians Insurance Company et al (627 NW2d 484 [Wis 2001]. NLM UID: 0372403. PMID: NLM11665386. PY - 2001 SN - 0001-2092 SP - 525-528 ST - OR nursing law. 'Captain of the ship' doctrine continues to take on water T2 - AORN Journal TI - OR nursing law. 'Captain of the ship' doctrine continues to take on water UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107073556&site=ehost-live&scope=site VL - 74 ID - 891 ER - TY - JOUR AB - Mast cell activation has been shown to be an initiator and a key determinant of foreign body reactions. However, there is no non-invasive method that can quantify the degree of implant-associated mast cell activation. Taking advantage of the fact that fibrin deposition is a hallmark of mast cell activation around biomaterial implants, a near infrared probe was fabricated to have high affinity to fibrin. Subsequent invitro testing confirmed that this probe has high affinity to fibrin. Using a subcutaneous particle implantation model, we found significant accumulation of fibrin-affinity probes at the implant sites as early as 15min following particle implantation. The accumulation of fibrin-affinity probes at the implantation sites could also be substantially reduced if anti-coagulant - heparinwas administered at the implant sites. Further studies have shown that subcutaneous administration of mast cell activator - compound 48/80 - prompted the accumulation of fibrin-affinity probes. However, implant-associated fibrin-affinity probe accumulation was substantially reduced in mice with mast cell deficiency. The results show that our fibrin-affinity probes may serve as a powerful tool to monitor and measure the extent of biomaterial-mediated fibrin deposition and mast cell activation invivo. © 2013 Elsevier Ltd. AD - Department of Bioengineering, University of Texas at Arlington, Arlington, TX 76019, United States Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung 807, Taiwan AU - Tsai, Y. T. AU - Zhou, J. AU - Weng, H. AU - Tang, E. N. AU - Baker, D. W. AU - Tang, L. DB - Scopus DO - 10.1016/j.biomaterials.2013.11.040 IS - 7 KW - Biocompatibility Biomaterial Fibrin Inflammation Invivo imaging Near infrared fluorescence M3 - Article N1 - Cited By :11 Export Date: 10 November 2020 PY - 2014 SP - 2089-2096 ST - Optical imaging of fibrin deposition to elucidate participation of mast cells in foreign body responses T2 - Biomaterials TI - Optical imaging of fibrin deposition to elucidate participation of mast cells in foreign body responses UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84891371448&doi=10.1016%2fj.biomaterials.2013.11.040&partnerID=40&md5=dd86a49b4eeea4a913d01077c6b83143 VL - 35 ID - 1263 ER - TY - JOUR AB - Introduction: Operations in the “Damage control” system (hereinafter only DC) are a modern surgical procedure for very serious injuries in situation when the patient is in life-threatening conditions caused not only by the injury itself, but by a delay in treatment and developing internal processes that are manageable, when the surgical reparation procedure is minimalized as for time. The main focus is on the Lethal Trias, which means: a/hypothermy, b/coagulopathy, c/acidosis. This trias (Shapiro et al. - 2000), hypothermy, haemocoagulopathy and acidosis, are the patophysiolological condition leading to death if not solved or solved late. System DC is suitable to use in mass casualties in extreme conditions. Definition: DAMAGE CONTROL is a multiphase approach to patient with life-threatening injuries, during which we try to re-establish or at least approximate patient's normal homeostasis, Rather than definitive trauma treatment in one phase, it attempts to keep the patient alive by dividing the treatment into several phases: 1. Admission and necessary examinations - in accordance with common procedure 2. First phase: quick stop bleeding, drainage or eventually stoma, tamponade of parenchymal organs, temporary laparotomy closure, examination of intrathoracic injuries - max. 40-50 minutes 3. ICU treatment: 24-48 hours, homeostatic adjustment 4. Second phase: resection surgeries, definitive treatment of bleeding arteries, tamponade removal max. 60-90 minutes 5. ICU treatment - 24-48hours, repetitive care leading to full stabilization of the patient - inner environment acidity normalization, temperature stabilization, normal volume, acceptable blood count and ionogram, coagulation approaching the norm 6. Third phase: restoration of intestinal continuity, definitive treatment of life non-threatening injuries in a longer time period. 7. ICU treatment .. etc. Damage Control Concept: The surgeon must decide for DC before the surgery. During the treatment the surgeon can reconsider the decision in case the DC approach does not seem to be beneficial. The following is thus important: 1. Timely indication which patient requires DC 2. decision for urgent surgery. In polytrauma it is necessary to consider which action will have priority and if more operational teams will be working simultaneously. 3. During the first phase sufficient perfusion of vital organs must be preserved, adequate ventilation, attempt for normothermia and maintenance or renewal of normocoagulation. 4. Decision how many surgical performances will be necessary, the right estimate of definitive surgery time and definitive wound closure. Hypothermy: - Drop in metabolic heat production during the hypovolemic shock - Unprotected body, unfavourable temperature conditions during the transport, wet closing and an open body cavity. - Cold fluids administrated intravenously during massive volume resuscitation/mentioned above/ - Temperature drop by 4-8 degrees C in 1 hour. At the temperature of 35°C mortality rate is almost 40x higher. - Lowering coagulation and cardiac output per minute Acidosis: - Hypovolemia leads to development of metabolic lactic acidosis - Metabolic acidosis is accompanied by heart arrhythmia, coagulation system disorder and lowered effect of catecholamines Coagulopathy: - Has multi factor basis (hypothermy, metabolic acidosis, blood loss, blood dilution from administered solutions, lowered thermoregulation, lowered synthesis of hemocoagulation factors and at the same time their increased consumption - DIC) - Hypocoagulation - twice increased Quick test and APTT - Hypercoagulation - consumption of coagulation factors -venous thrombosis, ARDS Indication for operation in the DC system: 1. Metabolic indications: Hypothermy with body temperature lower than 35°C. Absolute indication is temperature below 34°C, when hours lasting surgery leads almost certainly to death, acidosis with pH lower than 7.2 and with deficit of bases higher or equal 8, coagulopathy with APTT longer than 60 seconds. 2. Clinical indications: Penetrating abdominal trauma with hypotension (systolic BP is lower than 90 mmHg), high speed and/or multiple gunshot abdominal injury, blast abdominal injury, polytrauma with serious blunt abdominal injury, polytrauma with multiple serious bleeding sources, polytrauma without clear priorities of surgical treatment, complex pelvic injury combined with abdominal trauma, and mainly a higher number of casualties exceeding the possibilities of the medical institution (mass disasters, armed conflict). DAMAGE CONTROL in abdominal trauma 1. In the first phase laparotomy is carried out as a part of patient's resuscitation. The bleeding is kept under control (using vascular clamps and ligatures, tamponade of parenchymatous organs, pelvis and retroperitoneum) as well as contamination (removal of foreign bodies or quick catheterization of hollow organs into the wound without reconstruction attempts). Examination of all abdominal quadrants must be done to check the bleeding and serous bleeding mustn't be omitted because of haste! A quick closure of abdominal wall follows - we do not close aponeurosis! The key to success is in immediacy and simplicity. 2. The second phase continues by resuscitation in ICU or inpatient part of Critical Care Department. It involves above all proper warming up of the patient and optimizing ventilation and perfusion of the organism. 3. The third phase is reoperation considering a definitive reconstruction of organs. The decision is up to the surgeon after agreement with an anesthesiologist. If one of the definitive reconstruction surgeries lead to homeostasis deterioration or if other blood losses occur, this could be postponed to the later phase after recurrent stabilization at ICU. In the third phase arteries and hollow organs are reconstructed, definitive treatment of tamponed organs and areas is done as well as search and follow-up treatment of omitted minor injuries. It is then followed, according to the results, by temporary or definitive abdominal closure. DAMAGE CONTROL in chest injury 1. Urgent ambulatory thoracotomy (UAT) is often suitable, which is thoracotomy carried out at the hospital emergency admission room. It is considered as a part of the first operation phase, which continues after the patient's transfer to the operating theatre. The aim of UAT is above all to release the pericardial tamponade and in case of penetrating heart injury to provide its temporary treatment. According to the authors' experience, it is possible to use skin staplers. Direct cardiac massage is also possible, as well as temporary stapling the pulmonary hilum as a short term solution of vast pulmonary laceration. Another reason is a relatively easy closure of the distal part of thoracic aorta in left hemithorax in expected massive bleeding in abdominal cavity. Blind stapling in abdominal cavity under the diaphragm, recommended as emergency ambulatory surgery in many scientific resources, is technically much more demanding and requires considerable experience of the performing surgeon. 2. As a part of the first phase after a prospective UAT heart and lungs are treated in the operation theatre (parenchymal suturing, extra-anatomic resection etc.), artery ligation, or building an inner by-pass using a shunt (according to localization and the state of the patient). Treatment of the main bronchus or trachea is necessary. Esophagus treatment can be left for secondary treatment or potential second operation after the patient stabilization. A catheter probe is necessary to be placed over the injury to the stomach. 3. ICU treatment represents the second phase and is identical with the above mentioned second phase in abdominal trauma using DC. (Figure Presented) 4. The third phase is usually thorax reopening and definitive treatment of esophagus, pericardium or the by-passed injured arteries. Pericardium should be left open unless cardiac herniation may occur. AD - M. Hájek, Military Hospital of the Czech Army, Department of Surgery and Medical Rescue of Western Bohemia, Czech Republic AU - Hájek, M. AU - Dobeš, D. DB - Embase DO - 10.1007/s10353-016-0442-0 IS - 3 KW - blood clotting factor catecholamine endogenous compound abdominal blunt trauma abdominal cavity abdominal penetrating trauma abdominal wall acidity adult respiratory distress syndrome ambulatory surgery anesthesiologist aponeurosis artery ligation artificial ventilation bleeding blood cell count blood clotting disorder catheterization cold stress contamination deterioration diaphragm follow up foreign body gunshot injury heart arrhythmia heart injury heart massage heart output heart tamponade hemodilution hiatus hernia homeostasis hospital patient human hypotension hypovolemic shock intestine intravenous drug administration laceration lactic acidosis laparotomy lung hilus main bronchus mass disaster metabolic acidosis mortality rate multiple trauma operating room partial thromboplastin time pelvis perfusion plastic surgery reoperation resuscitation retroperitoneum skin stoma surgeon surgery synthesis systolic blood pressure thermogenesis thermoregulation thoracic aorta thoracotomy thorax injury trachea vascular clamp vein thrombosis velocity war warming wound closure LA - English M3 - Conference Abstract N1 - L617893948 2017-08-24 PY - 2016 SN - 1682-4016 SP - S190-S192 ST - Operations in “Damage Control” System -common in extreme conditions T2 - European Surgery - Acta Chirurgica Austriaca TI - Operations in “Damage Control” System -common in extreme conditions UR - https://www.embase.com/search/results?subaction=viewrecord&id=L617893948&from=export http://dx.doi.org/10.1007/s10353-016-0442-0 VL - 48 ID - 398 ER - TY - JOUR AB - Development of endovascular abdominal aortic aneurysms repair (EVAR), now in its 4th decade, has involved at least 16 different devices, not counting major modifications of some, only 4 of which have emerged from clinical trials and gained US Food and Drug Administration approval. The main impetus behind EVAR has been its potential for significantly reducing procedural mortality and morbidity, but it was also expected to speed recovery and reduce costs through decreased use of hospital resources. At the outset, EVAR was touted as a better alternative to OPEN in high-risk patients with large abdominal aortic aneurysms, and to "watchful waiting" (periodic ultrasound surveillance) for those with small abdominal aortic aneurysms. This new technology has evoked a mixed response with enthusiasts and detractors debating its pros and cons. Bias and conflict of interest exist on both sides. This review will attempt to present a balanced review of the development and current status of this controversial competition between EVAR and OPEN, comparing them in terms of the following key considerations: mortality and morbidity, complications, failure modes and durability, and costs. © 2012 Elsevier Inc. AD - R.B. Rutherford, 14337 Dorsal Street, Corpus Christi, TX 74418, United States AU - Rutherford, R. B. DB - Embase Medline DO - 10.1053/j.semvascsurg.2012.03.005 IS - 1 KW - abdominal aortic aneurysm aortointestinal fistula article disease severity endoleak endovascular aneurysm repair endovascular stent graft repair false aneurysm foreign body health care cost high risk patient hospital cost human intermethod comparison morbidity mortality open surgery priority journal quality of life stent surgical approach surgical technique survival rate survival time thrombosis treatment response AneuRx LA - English M3 - Article N1 - L364803786 2012-05-22 2012-05-30 PY - 2012 SN - 0895-7967 1558-4518 SP - 39-48 ST - Open Versus Endovascular Stent Graft Repair for Abdominal Aortic Aneurysms: An Historical View T2 - Seminars in Vascular Surgery TI - Open Versus Endovascular Stent Graft Repair for Abdominal Aortic Aneurysms: An Historical View UR - https://www.embase.com/search/results?subaction=viewrecord&id=L364803786&from=export http://dx.doi.org/10.1053/j.semvascsurg.2012.03.005 VL - 25 ID - 518 ER - TY - JOUR AB - PURPOSE:: To evaluate characteristics and prognostic factors for functional success in eyes that present with no light perception (NLP) after open globe trauma. METHODS:: The medical records of all subjects presenting to a single university referral center with visual acuity (VA) of NLP after sustaining an open globe eye injury from January 1, 2001, through June 30, 2010, were retrospectively analyzed to determine epidemiologic and clinical factors associated with visual outcomes. RESULTS:: Of the 73 NLP eyes (73 patients) that underwent primary repair and were included in the study, final VA was 20/100 in 1 eye (1%), counting fingers in 2 eyes (3%), hand motion in 9 eyes (12%), light perception in 5 eyes (7%), and NLP in 56 eyes (77%). Recovery of some vision on postoperative Day 1, pars plana vitrectomy operation, and Zone 2 injury were significantly associated with an improvement in final VA. Zone 3 injuries were the most likely to result in NLP final VA, although this difference was not statistically significant. CONCLUSION:: Visual recovery to light perception or better on postoperative Day 1 increases the likelihood of having a long-term improvement in VA. Pars plana vitrectomy may be beneficial in such eyes if posterior segment abnormalities are noted. AD - Institute of Ophthalmology and Visual Sciences, New Jersey Medical School, Doctors Office Center, Suite 6100, PO Box 1709, Newark, NJ 07101-1709, United States AU - Soni, N. G. AU - Bauza, A. M. AU - Son, J. H. AU - Langer, P. D. AU - Zarbin, M. A. AU - Bhagat, N. DB - Scopus DO - 10.1097/IAE.0b013e318263cefb IS - 2 KW - anti-VEGF bevacizumab macular telangiectasia ranibizumab subretinal neovascularization M3 - Article N1 - Cited By :24 Export Date: 10 November 2020 PY - 2013 SP - 380-386 ST - Open globe ocular trauma: Functional outcome of eyes with no light perception at initial presentation T2 - Retina TI - Open globe ocular trauma: Functional outcome of eyes with no light perception at initial presentation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84873406477&doi=10.1097%2fIAE.0b013e318263cefb&partnerID=40&md5=8d66eae1886355ae2352b8e76614b56d VL - 33 ID - 1332 ER - TY - JOUR AN - 106549459. Language: English. Entry Date: 20051209. Revision Date: 20150711. Publication Type: Journal Article AU - Hughes, C. DB - ccm DP - EBSCOhost IS - 10 KW - Surgical Count Procedure N1 - commentary; letter. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 100935999. PMID: NLM16252464. PY - 2005 SN - 1467-1026 SP - 407-407 ST - Open forum. Readers' letters: counting swabs...'Surgical equipment and materials left in patients' (BJPN 15(6):259-265) T2 - British Journal of Perioperative Nursing TI - Open forum. Readers' letters: counting swabs...'Surgical equipment and materials left in patients' (BJPN 15(6):259-265) UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106549459&site=ehost-live&scope=site VL - 15 ID - 939 ER - TY - JOUR AB - Actinomycosis is a rare chronic disease caused by a group of anaerobic Gram-positive bacteria that colonize the mouth, colon, and urogenital tract. Infection involving the cervicofacial area is the most common clinical presentation, followed by that of the pelvic and thoracic areas. The preoperative diagnosis of abdominal actinomycosis is difficult because the condition can be easily confused with malignancy, tuberculosis, or other inflammatory diseases. We report a case of omental actinomycosis mimicking a foreign body. Actinomycosis is diagnosed based on the histopathologic demonstration of sulfur granules in a tissue or organ that was surgically removed. Following confirmative diagnosis by surgical intervention, the patient was treated with oral doxycycline 100mg twice daily for 6 months. A follow-up abdominopelvic computed tomography after 16 months showed no evidence of inflammation. Moreover, the patient no longer had disease-associated symptoms and exhibited normal laboratory findings. AD - Department of Surgery, Chung Ang University Hospital, 224-1, Heuk Seok-Dong, Seoul, Dongjak-Ku, 156-755, South Korea AU - Choi, Y. S. AU - Park, Y. G. DB - Scopus DO - 10.1055/s-0043-110573 IS - 7 KW - actinomycosis foreign body omentum M3 - Article N1 - Export Date: 10 November 2020 PY - 2017 SP - 675-678 ST - Omental actinomycosis imitating a foreign body infection T2 - Zeitschrift fur Gastroenterologie TI - Omental actinomycosis imitating a foreign body infection UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85025108521&doi=10.1055%2fs-0043-110573&partnerID=40&md5=5c808a12b3f9dbb02175433df7ec5844 VL - 55 ID - 1130 ER - TY - JOUR AB - BACKGROUND: Eosinophilic oesophagitis clinically presents with recurrent episodes of dysphagia and food impaction. Recently, we observed patients with noncardiac chest pain and eosinophilic oesophagitis. AIMS: To estimate the prevalence of abnormal eosinophilic infiltration in noncardiac chest pain patients and examine diagnostic utility of demographic, clinical and endoscopic variables to predict eosinophilic oesophagitis. METHODS: Retrospective study of 171 consecutive patients referred for EGD evaluation of noncardiac chest pain. Endoscopic signs consistent with eosinophilic oesophagitis were recorded. The histological findings were grouped as normal: 0-5 eosinophils/high power field (e/hpf), indeterminate: 6-20 e/hpf, and eosinophilic oesophagitis: ≥21 e/hpf. Abnormal eosinophilic infiltration was defined as ≥6 e/hpf. RESULTS: Abnormal eosinophilic infiltrate was noted in 24 patients (14%). Thirteen (8%) had indeterminate counts, while 11 (6%) had eosinophilic oesophagitis. Compared with normal, those with abnormal oesophageal eosinophilic infiltration were more likely to be male (71% vs. 34%, P=0.001), have allergies (29% vs. 12%, P=0.050), have current GER symptoms (42% vs. 18%, P=0.013), rings (54% vs. 22%, P=0.002), furrows (21% vs. 1%, P<0.001) and abnormal eosinophilic oesophagitis findings on endoscopy (67% vs. 32%, P=0.001). Of the 24 abnormal patients, 23 (96%) were either male or had rings, furrows, or white specks. Conversely, 68 of 69 patients (99%) who were female did not have rings, furrows, or white specks, and endoscopy was normal. Eight patients (33%) with abnormal eosinophilic infiltration had a normal endoscopy. CONCLUSIONS: Eosinophilic oesophagitis should be considered in the evaluation of noncardiac chest pain. Our findings suggest that oesophageal biopsies should be obtained particularly in males with recurrent unexplained chest pain, whether endoscopy is normal or abnormal. AD - Gastroenterology Unit, Mayo Clinic Florida, 4500 San Pablo Road, Jacksonville, FL 32224, USA. achem.sami@mayo.edu AN - 21466568 AU - Achem, S. R. AU - Almansa, C. AU - Krishna, M. AU - Heckman, M. G. AU - Wolfsen, H. C. AU - Talley, N. J. AU - DeVault, K. R. DA - Jun DO - 10.1111/j.1365-2036.2011.04652.x DP - NLM ET - 2011/04/07 IS - 11 KW - Adult Aged Aged, 80 and over Chest Pain/*etiology Deglutition Disorders/*etiology Endoscopy, Digestive System/methods Eosinophilic Esophagitis/complications/*diagnosis Esophagus/*physiology Female Food Foreign Bodies/*etiology Humans Male Middle Aged Predictive Value of Tests Retrospective Studies Sex Factors LA - eng N1 - 1365-2036 Achem, S R Almansa, C Krishna, M Heckman, M G Wolfsen, H C Talley, N J DeVault, K R Journal Article England Aliment Pharmacol Ther. 2011 Jun;33(11):1194-201. doi: 10.1111/j.1365-2036.2011.04652.x. Epub 2011 Apr 5. PY - 2011 SN - 0269-2813 SP - 1194-201 ST - Oesophageal eosinophilic infiltration in patients with noncardiac chest pain T2 - Aliment Pharmacol Ther TI - Oesophageal eosinophilic infiltration in patients with noncardiac chest pain VL - 33 ID - 106 ER - TY - JOUR AB - A 27-year-old man presented to the emergency department with metallic-like foreign-body deposition on the entire aspect of both corneas associated with intense irritation, tearing, and photophobia. The corrected distance visual acuity (CDVA) was counting fingers in the right eye and light perception (LP) in the left eye. Slitlamp examination revealed diffuse, galaxy-like, golden-brown confluent deposits on the cornea, sclera, and conjunctiva of both eyes. The eyes were irrigated several times, followed by foreign-body removal and corneal repair. A penetrating keratoplasty was later performed in the right eye. After 1 year of follow-up, the patient was asymptomatic and the CDVA improved in the right eye but remained LP in the left eye due to macular scar formation secondary to severe tractional macular edema. AD - M. Naderi, Department of Ophthalmology, Baqiyatallah University of Medical Sciences, Bina Eye Hospital Research Center, Tehran, Iran AU - Naderi, M. AU - Jadidi, K. AU - Alishiri, A. AU - Mosavi, S. A. C1 - mydriacyl DB - Embase DO - 10.1016/j.jcro.2013.08.003 IS - 2 KW - betamethasone erythromycin gold tropicamide adult article case report cornea opacity cornea perforation drug withdrawal epiphora eye examination eye irritation eye lavage eyelid edema human intraocular foreign body iris disease keratoplasty laceration lens implantation lensectomy low vision photophobia priority journal pupil disease scar slit lamp vitrectomy young adult mydriacyl LA - English M3 - Article N1 - L601972269 2015-02-06 2015-02-11 PY - 2013 SN - 2214-1677 SP - e41-e43 ST - Ocular golden galaxy T2 - JCRS Online Case Reports TI - Ocular golden galaxy UR - https://www.embase.com/search/results?subaction=viewrecord&id=L601972269&from=export http://dx.doi.org/10.1016/j.jcro.2013.08.003 VL - 1 ID - 496 ER - TY - JOUR AB - Topical antibiotic and steroid ointments are sometimes used topically at the conclusion of intraocular surgery, and inadvertent entry into the eye has been reported. Dispersed ointment droplets or consolidated globules in the anterior chamber (AC) can sometimes be visualized on exam. Occasionally, intraocular ointment is found incidentally without apparent toxic effect, but retained ointment usually presents with early or delayed intraocular inflammation, pressure rise, macular edema, or corneal edema. The usual treatment for toxicity from retained ointment is removal of the ointment. While the complication of ointment-induced cystoid macular edema has been reported, there is paucity of literature on the anatomical response and eventual visual outcome of patients who have been treated for long-standing edema from retained ointment. We present a case of a patient who presented with history of poor vision since the time of cataract surgery 33 months prior, who had cystoid macular edema, reduced endothelial cell count, and apparent Maxitrol ointment (neomycin, polymyxin B sulfate, and dexamethasone in paraffin vehicle; Novartis Pharmaceuticals UK) floating in the AC. The patient was treated with AC washout and sub-Tenon injection of triamcinolone. His vision, retinal architecture by optical coherence tomography, endothelial cell count, and pachymetry has been followed for 9 months following this treatment. © 2018 The Author(s). Published by S. Karger AG, Basel. AD - Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States AU - Sanders, R. N. AU - Warner, D. B. AU - Adams, L. R. AU - Sallam, A. A. AU - Uwaydat, S. H. DB - Scopus DO - 10.1159/000495002 IS - 3 KW - Cystoid macular edema Endothelial cell loss Intraocular ointment Optical coherence tomography Specular microscopy M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 SP - 487-492 ST - Ocular complications from retained intraocular ointment discovered 33 months after cataract surgery T2 - Case Reports in Ophthalmology TI - Ocular complications from retained intraocular ointment discovered 33 months after cataract surgery UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85058803312&doi=10.1159%2f000495002&partnerID=40&md5=0293963d852468362c2f3d44e31f9462 VL - 9 ID - 1066 ER - TY - JOUR AB - Hypothesis: The adhesive octylcyanoacrylate is not associated with significant inner ear toxicity in a guinea pig model. Background: Many cyanoacrylate adhesives have been investigated for use in otologic surgery, but variable ototoxicity has been reported. Octylcyanoacrylate is a medical- grade adhesive with many properties that make it ideal for use in the ear. It is free of contaminants; it forms a strong, flexible bond; and it inhibits the growth of gram-positive organisms in culture. This is the first study to assess the ototoxicity of this new adhesive. Methods: Fourteen adult guinea pigs were used. Preoperative auditory brainstem responses (ABRs) were determined. Bilateral antrotomies were performed, and the ears were randomized to adhesive and control (saline) groups. In the adhesive ears, 0.5 or 0.1 mL of octylcyanoacrylate was instilled into the middle ear. Eight weeks later, postoperative ABRs were determined, the animals were killed, and the temporal bones were removed. Middle ear changes were noted, and the ossicular chain was assessed. Cochlear hair cell analyses were performed. Histologic assessment of the middle ear mucosa was performed. Results: There was a higher incidence of conductive hearing loss in the adhesive group secondary to fixation of the ossicular chain, but there was no significant difference in bone conduction thresholds. The median postoperative bone conduction thresholds (dB peak sound pressure level) was 15.0 in the control group and 17.5 in the adhesive group, p = 0.89. There was also no significant difference in inner hair cell counts (0.4% vs. 0.5% median hair cell loss, p = 0.72) or outer hair cell counts (3.7% vs. 3.0% median hair cell loss, p = 0.23) for the adhesive and control groups, respectively. Histopathologic analysis of the middle ear mucosa demonstrated variable mild to moderate foreign body reaction with no evidence of mucosal ulceration or necrosis. Conclusions: A large amount of octylcyanoacrylate placed in the middle ear of the guinea pig did not cause any morphologic or functional evidence of inner ear toxicity. This new adhesive is a promising tool for otologic surgery. AD - Michigan Ear Institute, Farmington Hills, MI, United States Providence Hospital, Southfield, MI, United States Department of Otolaryngology, University of Michigan, Ann Arbor, MI, United States Hear. Inst. for Children and Adults, 2400 Samaritan Drive, San Jose, CA 95124, United States AU - Maw, J. L. AU - Kartush, J. M. AU - Bouchard, K. AU - Raphael, Y. DB - Scopus DO - 10.1016/s0196-0709(00)80037-x IS - 3 KW - Cyanoacrylate adhesive Inner ear toxicity Otologic surgery Tissue adhesives M3 - Article N1 - Cited By :17 Export Date: 10 November 2020 PY - 2000 SP - 310-314 ST - Octylcyanoacrylate: A new medical-grade adhesive for otologic surgery T2 - American Journal of Otology TI - Octylcyanoacrylate: A new medical-grade adhesive for otologic surgery UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034026351&doi=10.1016%2fs0196-0709%2800%2980037-x&partnerID=40&md5=47589054cfbab07103c1ffabd5800fb0 VL - 21 ID - 1682 ER - TY - JOUR AB - We report 8 cases of blunt trauma in patients with a Verisyse phakic intraocular lens (pIOL) (AMO). Two cases resulted in dislocation of the pIOL that required repositioning; the other 6 were managed conservatively. In all cases, the outcomes were satisfactory, with no further complications. The cases represent scenarios that patients and physicians might encounter postoperatively and describe ways to manage the complication. © 2007 ASCRS and ESCRS. AD - Department of Ophthalmology and Visual Science, University of Utah, Moran Eye Center, Salt Lake City, UT, United States AU - Moshirfar, M. AU - Dodd, J. G. AU - Muir, G. J. AU - Gagnon, M. R. DB - Scopus DO - 10.1016/j.jcrs.2006.08.055 IS - 1 M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2007 SP - 166-169 ST - Occurrence and prognosis of nonpenetrating injuries in eyes with Verisyse iris-supported phakic intraocular lens T2 - Journal of Cataract and Refractive Surgery TI - Occurrence and prognosis of nonpenetrating injuries in eyes with Verisyse iris-supported phakic intraocular lens UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33845769240&doi=10.1016%2fj.jcrs.2006.08.055&partnerID=40&md5=b3e3bc353f30586e29e75fdf76513512 VL - 33 ID - 1570 ER - TY - JOUR AB - Foreign body aspiration (FBA), if retained and undiagnosed can lead to recurrent post-obstructive pneumonia, atelectasis or bronchiectasis. Aspiration is of concern in children, elderly and adults with neurological deficits. FB aspiration in healthy young adults without neurological or psychiatric disorders is rare. We report a case of recurrent pneumonia with complicated loculated parapneumonic effusion secondary to unknown aspiration event of a plastic foreign body. A 33-year-old male with a history of tobacco use, family history of lung cancer presented with fever, productive cough, dyspnea and right-sided pleuritic chest pain. He reported multiple episodes of pneumonia in the last 3 months. He was afebrile and hemodynamically stable on presentation. Reduced breath sounds were auscultated over the right basal area with dullness to percussion. Complete blood count revealed leukocytosis 30,000/mm3with left shift. Chest X-ray revealed a large right-sided pleural effusion. Computerized tomography (CT) chest demonstrated a large right-sided pleural effusion with evidence of loculation and associated right middle and lobe atelectasis. He was empirically started on vancomycin, piperacillin/tazobactam and levofloxacin. A right-sided pigtail chest tube was placed with pleural fluid (PF) sample consistent with complicated exudate (pH 7.10, LDH 743 units/L). PF cultures remained negative. Dornase alpha and alteplase was used to lyse the septations with total drainage of around 3.5 liters of pleural fluid with partial lung expansion. Flexible bronchoscopy with bronchoalveolar alveolar lavage (BAL) to evaluate persistent lower lobe atelectasis showed concerns of foreign body (FB) with surrounding granulation tissue. BAL fluid cultures and endobronchial biopsies were unrevealing. Rigid bronchoscopy revealed a foreign body covered by reactive tissue partially occluding the right lower lobe bronchus (RB). Pathologic analysis revealed reactive granulation tissue covering 0.8 cm plastic material Patient denied any memory of the event of aspiration. The diagnosis of FBA requires a high degree of clinical suspicion in healthy adults as sign and symptoms can be subtle. Patients may report the aspiration event or recall on history. CXR and CT scan can help visualize the FB if it is radio-opaque. Despite no recall of history or imaging concerns, recurrent pneumonia in the same location and persistent atelectasis raised FBA concerns in our case. Flexible bronchoscopy is the intervention of choice for endobronchial FB removal, with RB reserved for failed attempts or proximal obstruction. Therefore, FBA although uncommon in a healthy individual should be considered in individuals with a chronic cough, recurrent pneumonia or imaging evidence of a mass lesion. AD - S.H. Ijaz, Internal Medicine, Oklahoma University Health Sciences Center, Oklahoma City, OK, United States AU - Ijaz, S. H. AU - Hussain, S. AU - Christian, F. G. AU - Youness, H. DB - Embase IS - 9 KW - alteplase dornase alfa levofloxacin piperacillin plus tazobactam vancomycin abnormal respiratory sound adult aged atelectasis blood cell count body weight bronchiectasis cancer recurrence case report chest tube chronic cough clinical article computer assisted tomography conference abstract drug combination dyspnea family history fever fiberoptic bronchoscopy foreign body aspiration granulation tissue human human tissue lavage fluid leukocytosis lung alveolus lung cancer male memory mental disease neurologic disease obstruction percussion pleura effusion pleura fluid pneumonia surgery thorax pain thorax radiography tobacco use LA - English M3 - Conference Abstract N1 - L630355197 2020-01-01 PY - 2019 SN - 1535-4970 ST - Occult foreign body aspiration presenting as recurrent pneumonia with complicated parapneumonic effusion T2 - American Journal of Respiratory and Critical Care Medicine TI - Occult foreign body aspiration presenting as recurrent pneumonia with complicated parapneumonic effusion UR - https://www.embase.com/search/results?subaction=viewrecord&id=L630355197&from=export VL - 199 ID - 317 ER - TY - JOUR AD - Columbus Hospital, Newark, N.J., USA. AN - 12910737 AU - Erickson, S. DA - Jul DP - NLM ET - 2003/08/13 IS - 7 KW - Efficiency, Organizational *Foreign Bodies Humans Medical Errors/*prevention & control Operating Room Nursing/*standards *Surgical Instruments United States LA - eng N1 - Erickson, Sueellen Journal Article United States Mater Manag Health Care. 2003 Jul;12(7):32-4. PY - 2003 SN - 1059-4531 (Print) 1059-4531 SP - 32-4 ST - O.R. Left behind. Counting surgical instruments reduces medical errors T2 - Mater Manag Health Care TI - O.R. Left behind. Counting surgical instruments reduces medical errors VL - 12 ID - 43 ER - TY - JOUR AN - 106505217. Language: English. Entry Date: 20050826. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 2 KW - Perioperative Nursing -- Standards -- New Zealand Microscopy New Zealand Surgical Count Procedure N1 - standards. Journal Subset: Australia & New Zealand; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. PY - 2001 SN - 1174-7579 SP - 8-8 ST - NZ standards. N.Z. perioperative standards & guidelines for safe practice T2 - Dissector TI - NZ standards. N.Z. perioperative standards & guidelines for safe practice UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106505217&site=ehost-live&scope=site VL - 29 ID - 941 ER - TY - JOUR AN - 106472459. Language: English. Entry Date: 20050624. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 11 KW - Perioperative Nursing -- Legislation and Jurisprudence -- Pennsylvania Surgical Sponges -- Legislation and Jurisprudence -- Pennsylvania Surgical Count Procedure -- Legislation and Jurisprudence -- Pennsylvania Employment Termination -- Legislation and Jurisprudence -- Pennsylvania Insurance, Unemployment -- Legislation and Jurisprudence -- Pennsylvania Pennsylvania N1 - legal case. Journal Subset: Blind Peer Reviewed; Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Legal Case: Aceto-Long v. Unemployment Comp. Bd., No.2205 CD2004 (Pa.Commw2/28/2005). NLM UID: 100936959. PMID: NLM15926626. PY - 2005 SN - 1528-848X SP - 4-4 ST - Nursing law case on point. Nurse terminated for botching sponge count denied U.I. benefits T2 - Nursing Law's Regan Report TI - Nursing law case on point. Nurse terminated for botching sponge count denied U.I. benefits UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106472459&site=ehost-live&scope=site VL - 45 ID - 946 ER - TY - JOUR AD - Adjunct Professor, New York University AN - 107053027. Language: English. Entry Date: 20010921. Revision Date: 20170831. Publication Type: Journal Article AU - Eskreis-Nelson, T. DB - ccm DP - EBSCOhost IS - 3 KW - Treatment Errors -- Legislation and Jurisprudence -- United States Negligence -- Legislation and Jurisprudence -- United States Malpractice -- Legislation and Jurisprudence -- United States Nursing Care -- Legislation and Jurisprudence -- United States Liability, Legal Nursing Staff, Hospital Physicians Medication Errors Hysteroscopy -- Adverse Effects Cesarean Section -- Adverse Effects Pressure Ulcer -- Nursing Shock, Septic -- Nursing Embolism, Air -- Etiology Surgical Count Procedure -- Nursing Surgical Sponges -- Adverse Effects Equipment Failure -- Legislation and Jurisprudence -- United States Catheters, Vascular -- Adverse Effects Wandering Behavior -- Legislation and Jurisprudence -- United States Psychiatric Patients -- Legislation and Jurisprudence -- United States Accidental Falls -- Prevention and Control Accidental Falls -- Legislation and Jurisprudence -- United States Risk Assessment Patient Assessment Documentation Damages, Legal Critical Care Nursing -- Legislation and Jurisprudence -- United States Emergency Nursing -- Legislation and Jurisprudence -- United States Obstetric Nursing -- Legislation and Jurisprudence -- United States Perioperative Nursing -- Legislation and Jurisprudence -- United States Home Nursing, Professional -- Legislation and Jurisprudence -- United States Infant, Newborn Adolescence Adult Female Male United States N1 - legal case. Journal Subset: Blind Peer Reviewed; Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 9514027. PY - 2000 SN - 1073-7472 SP - 49-59 ST - Nursing case law update. Medical errors and the need for nurses' continuing education T2 - Journal of Nursing Law TI - Nursing case law update. Medical errors and the need for nurses' continuing education UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107053027&site=ehost-live&scope=site VL - 7 ID - 876 ER - TY - JOUR AD - Adjunct Professor, New York University AN - 106904312. Language: English. Entry Date: 20020301. Revision Date: 20170831. Publication Type: Journal Article AU - Eskreis-Nelson, T. R. DB - ccm DP - EBSCOhost IS - 4 KW - Liability, Legal -- Legislation and Jurisprudence -- United States Legal Procedure -- Legislation and Jurisprudence -- United States Malpractice -- Legislation and Jurisprudence -- United States Negligence -- Legislation and Jurisprudence -- United States Damages, Legal Causal Attribution Statute of Limitations Wrongful Death Nursing Practice -- Legislation and Jurisprudence -- United States Obstetric Care -- Legislation and Jurisprudence -- United States Understaffing -- Legislation and Jurisprudence -- United States Birth Injuries -- Legislation and Jurisprudence -- United States Surgical Count Procedure -- Legislation and Jurisprudence -- United States Venipuncture -- Adverse Effects Medication Errors -- Legislation and Jurisprudence -- United States Reflex Sympathetic Dystrophy -- Legislation and Jurisprudence -- United States Perinatal Death -- Legislation and Jurisprudence -- United States Witness, Legal -- Legislation and Jurisprudence -- United States Male Female Pregnancy Infant, Newborn Aged, 80 and Over Inpatients United States N1 - legal case; review. Journal Subset: Blind Peer Reviewed; Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 9514027. PY - 2001 SN - 1073-7472 SP - 43-51 ST - Nursing case law update. Liability avoidance tactics in malpractice actions T2 - Journal of Nursing Law TI - Nursing case law update. Liability avoidance tactics in malpractice actions UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106904312&site=ehost-live&scope=site VL - 7 ID - 927 ER - TY - JOUR AD - J.M. Zuffoletto AU - Zuffoletto, J. M. DB - Medline DO - 10.1016/S0001-2092(07)67177-4 IS - 6 KW - article female human legal aspect legal liability malpractice operating room personnel surgery surgical sponge United States LA - English M3 - Article N1 - L23907890 1993-07-25 PY - 1993 SN - 0001-2092 SP - 1457-1458 ST - Nurses' vs surgeons' responsibility for sponge counts T2 - AORN journal TI - Nurses' vs surgeons' responsibility for sponge counts UR - https://www.embase.com/search/results?subaction=viewrecord&id=L23907890&from=export http://dx.doi.org/10.1016/S0001-2092(07)67177-4 VL - 57 ID - 670 ER - TY - JOUR AN - 3634408 AU - Tammeleo, A. D. DA - Mar DP - NLM ET - 1986/03/01 IS - 10 KW - Abdomen Alabama *Cesarean Section Female *Foreign Bodies Humans Operating Room Nursing/*legislation & jurisprudence Pregnancy *Surgical Equipment LA - eng N1 - Tammeleo, A D Case Reports Journal Article United States Regan Rep Nurs Law. 1986 Mar;26(10):1. PY - 1986 SN - 0034-3196 (Print) 0034-3196 SP - 1 ST - Nurses, doctors and sponge counts: liability T2 - Regan Rep Nurs Law TI - Nurses, doctors and sponge counts: liability VL - 26 ID - 11 ER - TY - JOUR AB - During the 2007 meeting of the Child Health Corporation of America Operating Room Director's Forum, members identified two major discrepancies in surgical count policies among the member hospitals: variations for instrument counts in pediatrics and exceptions to radiographic verification when needle counts were incorrect. The group agreed to collaboratively develop a pediatric count policy based on directors' expertise and current literature to help improve count practices. The task force members reviewed the literature as well as count policies from 30 member hospitals to identify and combine best practices and to create a single, standardized count policy. The project exemplifies a successful nurse-led, national group effort. The outcome is a policy that represents best practice in pediatrics and is a first step toward future opportunities to improve patient safety. AD - Children's Hospital Boston, Massachusetts, USA. AN - 22283913 AU - Norton, E. K. AU - Micheli, A. J. AU - Gedney, J. AU - Felkerson, T. M. DA - Feb DO - 10.1016/j.aorn.2011.11.009 DP - NLM ET - 2012/01/31 IS - 2 KW - Foreign Bodies/*prevention & control Humans Medical Errors/*prevention & control Needles Nurses Patient Safety Pediatrics/*standards Perioperative Nursing/methods/*standards *Practice Guidelines as Topic Surgical Instruments Surgical Procedures, Operative/methods/nursing/*standards LA - eng N1 - 1878-0369 Norton, Elizabeth K Micheli, Anne J Gedney, Jennifer Felkerson, Tiffin M Journal Article United States AORN J. 2012 Feb;95(2):222-7. doi: 10.1016/j.aorn.2011.11.009. PY - 2012 SN - 0001-2092 SP - 222-7 ST - A nurse-led approach to developing and implementing a collaborative count policy T2 - Aorn j TI - A nurse-led approach to developing and implementing a collaborative count policy VL - 95 ID - 122 ER - TY - JOUR AN - 1530515 AU - Langslow, A. DA - Jun DP - NLM ET - 1992/06/01 IS - 11 KW - *Cesarean Section Cholecystectomy Female *Foreign Bodies Humans Male Malpractice/*legislation & jurisprudence Medical Staff, Hospital/*legislation & jurisprudence Nursing Staff, Hospital/*legislation & jurisprudence Pregnancy Sterilization, Tubal United States LA - eng N1 - Langslow, A Case Reports Journal Article Legal Case Australia Aust Nurses J. 1992 Jun;21(11):31-2. PY - 1992 SN - 0045-0758 (Print) 0045-0758 SP - 31-2 ST - Nurse and the law. Relying on the count T2 - Aust Nurses J TI - Nurse and the law. Relying on the count VL - 21 ID - 19 ER - TY - JOUR AB - Treatment of damaged cardiac tissue in patients with high bleeding tendency can be very challenging, damaged myocardial tissue has a high rupture risk when being sutured subsequently on-going bleeding is a major risk factor for poor clinical outcome. We present a case demonstrating the feasibility in using a novel haemostatic collagen sponge for the management of a myocardial wound. This report is the first description in cardiac surgery where Hemopatch sponges are used to successfully seal a left ventricle wound. Our patient was diagnosed with endocarditis, had a low pre-operative haemoglobin count and underwent cardiac surgery for multiple valve repairs. The procedure was performed on cardiopulmonary bypass, which meant our patient had to be heparinized. Despite these major risk factors for bleeding Hemopatch managed to contain bleeding and seal the wound, no sutures were needed. AU - Jainandunsing, J. S. AU - Al-Ansari, S. AU - Woltersom, B. D. AU - Scheeren, T. W. AU - Natour, E. DB - Medline DO - 10.1186/s13019-015-0215-z KW - aortic valve stenosis case report complication coronary artery disease devices heart rupture heart surgery heart valve replacement hemostasis human male middle aged mitral valve stenosis procedures surgical sponge suture technique LA - English M3 - Article N1 - L609347844 2016-04-05 PY - 2015 SN - 1749-8090 SP - 12 ST - Novel hemostatic patch achieves sutureless epicardial wound closure during complex cardiac surgery, a case report T2 - Journal of cardiothoracic surgery TI - Novel hemostatic patch achieves sutureless epicardial wound closure during complex cardiac surgery, a case report UR - https://www.embase.com/search/results?subaction=viewrecord&id=L609347844&from=export http://dx.doi.org/10.1186/s13019-015-0215-z VL - 10 ID - 440 ER - TY - JOUR AB - In orthopedic patients, foreign body-associated infections, especially periprosthetic joint infections (PJIs), are a devastating complication of arthroplasty. Infection requires complex treatment, may result in long hospitalization and causes considerable costs. Multiple surgical revisions can be necessary in these patients, with a loss in function as well as in quality of life. The routine preoperative diagnostics include blood examination for C-reactive protein (CRP) and other biomarkers, as well as joint aspirate analysis for cell count, differentiation, and culture. Intraoperative specimens for histology and microbiology are also standard procedure. The microbiological examination of removed implants with sonication, in combination with the implementation of molecular biology techniques in microbiology, represent two novel techniques currently employed to enhance the differential diagnostics of PJI. We present here the step-wise procedure of analyzing joint aspirate and sonication fluid, using a cartridge-based multiplex polymerase chain reaction (PCR) system. Results were matched against conventional cultures and consensus criteria for PJI. Conventional microbiological cultures from tissue biopsies, joint aspirate and sonication fluid showed a sensitivity of 66.7%, 66.7%, and 88.9%, respectively, and a specificity of 82.3%, 54.6%, and 61.5%, respectively. The PCR diagnostic of the sonication fluid and the joint fluid showed a sensitivity of 50.0% and 55.6%, respectively, and both a specificity of 100.0%. Both PCR diagnostics combined had a sensitivity of 66.7% and a specificity of 100.0%. The multiplex PCR therefore presents a rapid diagnostic tool with moderate sensitivity but high specificity in diagnosing PJI. AD - Institute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn; hischebeth@microbiology-bonn.de. Department of Orthopaedics and Trauma Surgery, University Hospital Bonn. Institute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn. Division of EU Cooperation/Microbiology, Paul-Ehrlich-Institute. AN - 29286460 AU - Hischebeth, G. T. R. AU - Gravius, S. AU - Buhr, J. K. AU - Molitor, E. AU - Wimmer, M. D. AU - Hoerauf, A. AU - Bekeredjian-Ding, I. AU - Randau, T. M. C2 - PMC5755521 DA - Dec 3 DO - 10.3791/55147 DP - NLM ET - 2017/12/30 IS - 130 KW - Arthroplasty/*methods Humans Polymerase Chain Reaction/*methods Prostheses and Implants/*microbiology Prosthesis-Related Infections/*diagnosis Sonication/*methods LA - eng N1 - 1940-087x Hischebeth, Gunnar T R Gravius, Sascha Buhr, Johanna K Molitor, Ernst Wimmer, Matthias D Hoerauf, Achim Bekeredjian-Ding, Isabelle Randau, Thomas M Journal Article Research Support, Non-U.S. Gov't Video-Audio Media J Vis Exp. 2017 Dec 3;(130):55147. doi: 10.3791/55147. PY - 2017 SN - 1940-087x ST - Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction T2 - J Vis Exp TI - Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction ID - 205 ER - TY - JOUR AB - Introduction: The commonest causes of mechanical small bowel obstruction are postoperative adhesions and hernias. Other aetiologies include disease intrinsic to the bowel wall (e.g. tumour, stricture) and intraluminal obstruction (e.g. gallstones, foreign bodies). Here we report a case where pica caused obstruction secondary to ingestion of sandstone fragments. Case presentation: A 72 year old female with a virgin abdomen, presented to her GP with a 2 day history of abdominal pain, distension and vomiting. Her bowels had not opened for 4 days, but she was passing flatus. Upon arrival in the Emergency Department, she was dehydrated, tachycardic and tachypnoeic. On examination, her abdomen was soft, distended and maximally tender on the left side. Her white cell count was 31.8 and lactate 2.0. Other admission blood tests were unremarkable. A CT scan revealed a thickened segment of small bowel of uncertain aetiology. She underwent an emergency laparotomy. Findings were small bowel obstruction secondary to accumulation of sandstone fragments ranging in size from 0.5-3.0 cm, with multiple fragments in the large bowel. A small bowel enterotomy was performed, to remove the larger particles. Post-operative recovery was complicated by a lower respiratory tract infection, but the patient was discharged at Day 5. Conclusion: The patient denied ingestion of foreign bodies during initial assessment, but post operatively, she admitted pica for sandstone dating back a number of years. This novel case highlights the need to keep an open mind during the initial assessment of patients in the emergency setting. AD - E.L. Court, Royal United Hospital, Bath, United Kingdom AU - Court, E. L. AU - Courtney, E. D. DB - Embase KW - lactic acid abdominal pain aged case report computer assisted tomography emergency ward female flatulence foreign body human ingestion intestine surgery laparotomy large intestine leukocyte count lower respiratory tract infection pica small intestine obstruction tachycardia vomiting LA - English M3 - Conference Abstract N1 - L612841444 2016-10-25 PY - 2016 SN - 1463-1318 SP - 71 ST - Novel case report of small bowel obstruction secondary to pica for sandstone T2 - Colorectal Disease TI - Novel case report of small bowel obstruction secondary to pica for sandstone UR - https://www.embase.com/search/results?subaction=viewrecord&id=L612841444&from=export VL - 18 ID - 392 ER - TY - JOUR AB - Foreign body aspiration in children is frequently associated with unilateral emphysema or atelectasis on chest x-ray. Two cases are reported of tracheal or bilateral foreign bodies in which the original chest x-rays were read as normal, but the history was suggestive of the foreign body aspiration. Early bronchoscopy can prevent the long-term morbidity that results from unrecognized tracheobronchial foreign bodies. AN - 3780119 AU - Musemeche, C. A. AU - Kosloske, A. M. DA - Dec DO - 10.1177/000992288602501209 DP - NLM ET - 1986/12/01 IS - 12 KW - Bronchoscopy Child Diagnosis, Differential Female Foreign Bodies/diagnosis/*diagnostic imaging Humans Infant Male *Radiography, Thoracic Respiratory Tract Infections/diagnosis *Trachea LA - eng N1 - Musemeche, C A Kosloske, A M Case Reports Journal Article United States Clin Pediatr (Phila). 1986 Dec;25(12):624-5. doi: 10.1177/000992288602501209. PY - 1986 SN - 0009-9228 (Print) 0009-9228 SP - 624-5 ST - Normal radiographic findings after foreign body aspiration. When the history counts T2 - Clin Pediatr (Phila) TI - Normal radiographic findings after foreign body aspiration. When the history counts VL - 25 ID - 15 ER - TY - JOUR AB - Langerhans cells (LCs) are the most effective antigen presenting cells against foreign bodies and carcinogens. Since the oral cavity is a portal of entry for these antigens, the aim of this study was to morphologically classify CD1a+ LCs, quantify them in the normal and malignant buccal mucosa, and evaluate their relation to the age of patients. Healthy buccal mucosal samples collected from 16 patients undergoing reconstructive operation, and malignant samples obtained from 15 patients undergoing radical oncological resection. were processed for immunohistochemistry four- to five-micron thick sections were stained with CD1a antibody (CD1a). At 40X magnification, CD1a+ LCs were morphologically classified and quantified manually for a 25mm length of basement membrane using Cellsens image analysing software and the data was analysed. Two categories of CD1a+ LCs were identified in the normal and malignant buccal mucosa a) typical dendritic LCs and b) non-dendritic LCs (a new entity). Non-dendritic LCs were of significantly higher number compared to the typical dendritic LCs in the normal tissues (p -0.001). In the malignant group, the non-dendritic CD1a+ LCs were significantly fewer in number (p-0.004), when compared to the normal group. Non-dendritic LCs were also significantly fewer (p-0.026) in patients over 60 years of age. This is the first report of non-dendritic Langerhans cells in normal buccal mucosa and malignant buccal mucosa using the CD1a marker. The significantly higher number of these cells in normal tissues and younger individuals supports their role as accessory antigen presenting cells. © 2019 Sociedad Anatomica Espanola. All rights reserved. AD - Department of Anatomy, Christian Medical College, Vellore, 632002, India Department of Urology, Christian Medical College, Vellore, 632004, India Department of Surgery, Christian Medical College, Vellore, 632004, India MGR Medical University, Chennai, India AU - Mathew, J. K. AU - Pandian, R. M. K. AU - Gaikwad, P. AU - Rabi, S. AU - Nadu, T. DB - Scopus IS - 5 KW - Accessory antigen presenting cells Antigen presenting cells Dendritic Types of Langerhans cells M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 383-388 ST - Non-dendritic Langerhans cells: A new entity in normal and malignant buccal mucosa T2 - European Journal of Anatomy TI - Non-dendritic Langerhans cells: A new entity in normal and malignant buccal mucosa UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85072609255&partnerID=40&md5=e42639641303ef86af81d1b0699f1ca9 VL - 23 ID - 1003 ER - TY - JOUR AB - Nocardia nova is a less commonly isolated Nocardia species that was formerly classified as belonging to the Nocardia asteroides complex. This organism is a rare cause of primary cutaneous nocardiosis. We report a case of N. nova flexor tenosynovitis and abscess involving the right forearm after a remote inoculation injury. © 2018 Wolters Kluwer Health, Inc. All rights reserved. AD - Division of Infectious Diseases, Michigan Medicine, Infectious Diseases Section, VA Ann Arbor Healthcare System, 2215 Fuller Rd, Ann Arbor, MI 48105, United States Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI, United States AU - Linder, K. A. AU - Herc, E. S. AU - Kauffman, C. A. DB - Scopus DO - 10.1097/IPC.0000000000000579 IS - 5 KW - cutaneous nocardiosis Nocardia nova retained foreign body M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 SP - e22-e24 ST - Nocardia nova Tenosynovitis and Abscess after a Remote Gunshot Wound T2 - Infectious Diseases in Clinical Practice TI - Nocardia nova Tenosynovitis and Abscess after a Remote Gunshot Wound UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85053232994&doi=10.1097%2fIPC.0000000000000579&partnerID=40&md5=a5cae9b24db8df0053c2abaa024cfccc VL - 26 ID - 1062 ER - TY - JOUR AB - The counting process is designed to prevent retained foreign bodies while providing optimal perioperative patient safety. Intraoperative distractions are prevalent and potentially contribute to patient safety risks. Counting is an important preventative measure that is a human process prone to error, especially in this busy environment where multiple things are happening simultaneously. We sought to evaluate the impact of distractions during the count process on patient safety. Trained, nationally certified registered nurses used a validated tool to observe the number of interruptions that occurred during the count process in cardiac surgery. Observation included the key personnel that lead the count process including the scrub person, circulating nurse, attending surgeons, fellows, and residents of all disciplines. Observation included scheduled cases in the cardiac specialty for the adult population including all shifts (24 hours). The predictor in this study was distraction. The primary measure of distraction was the total number of distraction for each case. There are different distraction levels for each distraction. Thus, weighted distraction score for each case was created as the summation of distraction level and it is the secondary measure of distraction. To detect a medium effect size with 80% power at 0.05 level, we needed a minimum sample size of 54. We correlated the relationship between the number of interruptions observed and sequelae. Working together as a cohesive team to minimize interruptions can enhance patient safety and decrease additional workload across departments. AD - C.M. Cordella, NewYork-Presbyterian Hospital, Perioperative Services, 173 Fort Washington Avenue 3rd Floor, Room 606, New York, NY, United States AU - Kertesz, L. AU - Cordella, C. M. AU - Nadera, N. M. AU - Nelson, P. E. AU - Kahil, M. AU - Shim, S. H. AU - Holtzman, J. S. DB - Embase DO - 10.1016/j.jradnu.2019.09.004 IS - 1 KW - surgical equipment article effect size foreign body heart surgery human Medline multidisciplinary team observational study patient care patient safety pilot study priority journal procedures prospective study registered nurse retained foreign body sample size surgical count process surgical technique workload LA - English M3 - Article N1 - L2004001474 2019-12-23 2020-03-10 PY - 2020 SN - 1555-9912 1546-0843 SP - 57-62 ST - No Surgical Items Left Behind: A Multidisciplinary Approach to the Surgical Count Process T2 - Journal of Radiology Nursing TI - No Surgical Items Left Behind: A Multidisciplinary Approach to the Surgical Count Process UR - https://www.embase.com/search/results?subaction=viewrecord&id=L2004001474&from=export http://dx.doi.org/10.1016/j.jradnu.2019.09.004 VL - 39 ID - 284 ER - TY - JOUR AN - 105814224. Language: English. Entry Date: 20080919. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 4 KW - Nurses Operating Room Personnel Patient Safety Surgical Count Procedure N1 - brief item. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2008 SN - 0190-5066 SP - 42-42 ST - No interruptions during count to ensure accuracy T2 - Same-Day Surgery TI - No interruptions during count to ensure accuracy UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105814224&site=ehost-live&scope=site VL - 32 ID - 931 ER - TY - JOUR AB - BACKGROUND: Wear-resistant bearing materials may hypothetically reduce chronic inflammation in the pseudosynovial membrane as compared to less wear-resistant bearing materials such as polyethylene. We assessed the foreign body response in the pseudosynovial membrane in vivo after total hip replacement. METHODS: 37 patients from a larger prospective randomized trial of 225 patients had biopsies taken arthroscopically from the artificial hip joint (i.e. the pseudosynovial membrane) 1 year after insertion of the implant. All patients had an identical hip prosthesis (Bimetric-RingLoc) except for the bearing materials, which consisted of polyethylene on zirconia, CoCr on CoCr, or alumina on alumina. Histological quantification was performed on 2-mum-thick semi-thin plastic sections or paraffin sections by point counting technique to compare the volume fraction of macrophages, granulomas and endothelial cells in biopsies of the pseudosynovial membrane. RESULTS: The median macrophage volume fractions for polyethylene-on-zirconia bearing material (n = 15), CoCr-on-CoCr (n = 9), and alumina-on-alumina (n = 11) were 0.02, 0.04, and 0.004, respectively. The median granuloma volume fractions for polyethylene-on-zirconia (n = 13), CoCr-on-CoCr (n = 9), and alumina-on-alumina (n = 13) were 0.02, 0.04, and 0.02, respectively. The median endothelial cell volume fractions for polyethylene-on-zirconia (n = 15), CoCr-on-CoCr (n = 9), and alumina-on-alumina (n = 11) were 0.03, 0.02, and 0.05, respectively. Statistical analysis showed no significant differences between the three groups with the different bearings with respect to volume fraction of macrophages, granulomas and endothelial cells. INTERPRETATION: Our study demonstrated that a granulomatous inflammation is a common finding in non-loose implants as early as 1 year after the operation not demonstrating a difference in macrophages and granuloma formation with the various bearing materials. Thus a high volume fraction of macrophages was found in the osteoarthritis control group compared to the operated group. AD - Department of Orthopaedic Surgery, Frederiksberg University Hospital, Frederiksberg, Denmark. many@dadlnet.dk AN - 16819678 AU - Nygaard, M. AU - Elling, F. AU - Bastholm, L. AU - Søballe, K. AU - Borgwardt, A. DA - Jun DO - 10.1080/17453670610046325 DP - NLM ET - 2006/07/05 IS - 3 KW - Adult Aged Aged, 80 and over *Arthroplasty, Replacement, Hip/adverse effects/methods Biopsy/methods Female Femur Head Necrosis/surgery Follow-Up Studies Foreign-Body Reaction/etiology/immunology/*pathology Granuloma, Foreign-Body/pathology Hip Prosthesis/*adverse effects Humans Male Materials Testing Middle Aged Osteoarthritis, Hip/*pathology/surgery Prospective Studies Prosthesis Design Prosthesis Failure Synovial Membrane/pathology LA - eng N1 - Nygaard, Marianne Elling, Folmer Bastholm, Lone Søballe, Kjeld Borgwardt, Arne Comparative Study Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't England Acta Orthop. 2006 Jun;77(3):402-12. doi: 10.1080/17453670610046325. PY - 2006 SN - 1745-3674 (Print) 1745-3674 SP - 402-12 ST - No difference in early cellular response of the pseudo-synovial membrane after total hip arthroplasty: comparison of 3 combinations of bearing materials T2 - Acta Orthop TI - No difference in early cellular response of the pseudo-synovial membrane after total hip arthroplasty: comparison of 3 combinations of bearing materials VL - 77 ID - 60 ER - TY - JOUR AN - 106204815. Language: English. Entry Date: 20070105. Revision Date: 20150711. Publication Type: Journal Article DA - 2006 Spring DB - ccm DP - EBSCOhost IS - 3 KW - Perioperative Care Computers and Computerization Faculty, Nursing Information Resources Medical Records Perioperative Nursing Respiratory Tract Infections -- Drug Therapy Surgeons -- Education Surgical Count Procedure -- Methods Technology Volunteer Workers World Wide Web N1 - website. Journal Subset: Australia & New Zealand; Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. PY - 2006 SN - 1448-7535 SP - 13-18 ST - News roundup T2 - ACORN: The Journal of Perioperative Nursing in Australia TI - News roundup UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106204815&site=ehost-live&scope=site VL - 19 ID - 859 ER - TY - JOUR AN - 106204810. Language: English. Entry Date: 20070105. Revision Date: 20150820. Publication Type: Journal Article AU - Mitchell, L. DA - 2006 Spring DB - ccm DP - EBSCOhost IS - 3 KW - Retained Instruments -- Prevention and Control Surgical Count Procedure -- Methods Technology N1 - letter. Journal Subset: Australia & New Zealand; Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. PY - 2006 SN - 1448-7535 SP - 9-10 ST - New technology for surgical accountability T2 - ACORN: The Journal of Perioperative Nursing in Australia TI - New technology for surgical accountability UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106204810&site=ehost-live&scope=site VL - 19 ID - 910 ER - TY - JOUR AB - STUDY DESIGN: Retrospective study. PURPOSE: Missing cottonoids during and after spinal surgery is a persistent problem and account for the most commonly retained surgical instruments (RSIs) noticed during a final cottonoid count. The aim of this study was to enumerate risk factors and describe the sequence to look out for misplaced cottonoids during spinal surgery and provide an algorithm for resolving the problem. OVERVIEW OF LITERATURE: There are only a few case reports on RSIs among various surgical branches. The data is inconclusive and there is little evidence in the literature that relates to spinal surgery. METHODS: This retrospective study was conducted at Indian Spinal Injuries Centre. The data was collected from hospital records ranging from January 2013 to December 2017. The surgical cases in which cottonoid counts were inconsistent during or after the procedure were included in the study. The case files along with operating theater records were thoroughly screened for selecting those in which there was confirmed evidence of such an event. RESULTS: There were 7,059 spinal surgeries performed during the study period. Fifteen cases of miscounts were recorded with an incidence of one in every 471 cases. Cottonoids were most commonly lost under the shoes of the surgeon or assistants. In two instances, cottonoids were found in the surgical field and trapped in the interbody cage site. Based on these locations, a systematic search algorithm was created. CONCLUSIONS: This study enumerates RSI risk factors in spinal surgical procedures and describes steps that can be followed to account for any missing cottonoids. The incidence of missing cottonoids can be decreased using a goal-oriented approach and ensuring that surgical teams work in collaboration. AD - Department of Spine Surgery, Indian Spinal Injuries Center, New Delhi, India. AN - 30326697 AU - Reddy, A. AU - Mahajan, R. AU - Rustagi, T. AU - Goel, S. A. AU - Bansal, M. L. AU - Chhabra, H. S. C2 - PMC6365781 DA - Feb DO - 10.31616/asj.2018.0136 DP - NLM ET - 2018/10/18 IS - 1 KW - Algorithms Cottonoids Re-exploration Retained foreign body Spine Surgical sponges LA - eng N1 - 1976-7846 Reddy, Abhinandan Mahajan, Rajat Rustagi, Tarush Goel, Shakti A Bansal, Murari L Chhabra, Harvinder Singh Journal Article Asian Spine J. 2019 Feb;13(1):1-6. doi: 10.31616/asj.2018.0136. Epub 2018 Oct 18. PY - 2019 SN - 1976-1902 (Print) 1976-1902 SP - 1-6 ST - A New Search Algorithm for Reducing the Incidence of Missing Cottonoids in the Operating Theater T2 - Asian Spine J TI - A New Search Algorithm for Reducing the Incidence of Missing Cottonoids in the Operating Theater VL - 13 ID - 222 ER - TY - JOUR AB - The first part of an article regarding the challenges and solutions for retained surgical items is presented. Topics discussed include an incident in a California hospital when a staff was not able to notice that a blue towel had gone into the patient during the abdominal surgery, the review conducted by Verna C. Gibbs, director of No Thing Left Behind, a surgical patient safety project, regarding counts of miscellaneous items, and data collected by the Oregon Patient Safety Commission. AN - 113009552. Language: English. Entry Date: 20160218. Revision Date: 20160219. Publication Type: Article. Journal Subset: Biomedical DB - ccm DP - EBSCOhost IS - 3 KW - Retained Instruments Patient Safety Documentation Surgery Outside the OR Root Cause Analysis Staff Development Quality Improvement Communication Interprofessional Relations Distraction Truth Disclosure N1 - Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2016 SN - 0190-5066 SP - 25-28 ST - New problems mean new solutions for retained surgical items T2 - Same-Day Surgery TI - New problems mean new solutions for retained surgical items UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=113009552&site=ehost-live&scope=site VL - 40 ID - 712 ER - TY - JOUR AB - Integral to the development of new biomaterials is the characterization of immune responses to biomaterial implants, and formulating methods to overcome or utilize these actions for therapeutic benefit. Neutrophils are an essential component of the immune response against biomaterials, but studies on the neutrophil-biomaterial interaction have been largely limited to characterizing their role in establishing an inflammatory microenvironment and antimicrobial activity at implant surfaces. Recent advances in neutrophil biology, especially recognition of their cellular heterogeneity, ability to suppress immune responses, the identification of a new process of cell death, and crosstalk with other immune cell types, have brought about a fundamental change in our perception regarding the activities of neutrophils. Herein, in the context of the progress in our comprehension of neutrophil function, potential avenues for effectively employing neutrophil activity to develop the next generation of regenerative biomaterials are discussed. © 2017 American Chemical Society. AD - Centre for BioSystems Science and Engineering, Indian Institute of Science, Bengaluru, 560012, India AU - Jhunjhunwala, S. DB - Scopus DO - 10.1021/acsbiomaterials.6b00743 IS - 4 KW - fibrosis foreign body response polymorphonuclear cells tissue engineering M3 - Review N1 - Cited By :7 Export Date: 10 November 2020 PY - 2018 SP - 1128-1136 ST - Neutrophils at the Biological-Material Interface T2 - ACS Biomaterials Science and Engineering TI - Neutrophils at the Biological-Material Interface UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85045207626&doi=10.1021%2facsbiomaterials.6b00743&partnerID=40&md5=a1364b80ac801fee4053b82d839ecd3d VL - 4 ID - 1081 ER - TY - JOUR AB - In vivo implantation of sterile materials and devices results in a foreign body immune response leading to fibrosis of implanted material. Neutrophils, one of the first immune cells to be recruited to implantation sites, have been suggested to contribute to the establishment of the inflammatory microenvironment that initiates the fibrotic response. However, the precise numbers and roles of neutrophils in response to implanted devices remains unclear. Using a mouse model of peritoneal microcapsule implantation, we show 30-500 fold increased neutrophil presence in the peritoneal exudates in response to implants. We demonstrate that these neutrophils secrete increased amounts of a variety of inflammatory cytokines and chemokines. Further, we observe that they participate in the foreign body response through the formation of neutrophil extracellular traps (NETs) on implant surfaces. Our results provide new insight into neutrophil function during a foreign body response to peritoneal implants which has implications for the development of biologically compatible medical devices. © 2015 Jhunjhunwala et al. AD - David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, United States Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, United States Harvard-MIT Division of Health Science and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, United States Department of Anesthesiology, Boston Children's Hospital, Boston, MA 02115, United States Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, United States Department of Molecular Medicine, Diabetes Center of Excellence, University of Massachusetts Medical School, Worcester, MA 01605, United States Department of Pediatrics, University of Massachusetts Medical School, Worcester, MA 01605, United States Department of Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, United States Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, United States Department of Biological and Environmental Engineering, Cornell University, Ithaca, NY 14853, United States AU - Jhunjhunwala, S. AU - Aresta-DaSilva, S. AU - Tang, K. AU - Alvarez, D. AU - Webber, M. J. AU - Tang, B. C. AU - Lavin, D. M. AU - Veiseh, O. AU - Doloff, J. C. AU - Bose, S. AU - Vegas, A. AU - Ma, M. AU - Sahay, G. AU - Chiu, A. AU - Bader, A. AU - Langan, E. AU - Siebert, S. AU - Li, J. AU - Greiner, D. L. AU - Newburger, P. E. AU - Von Andrian, U. H. AU - Langer, R. AU - Anderson, D. G. C7 - e0137550 DB - Scopus DO - 10.1371/journal.pone.0137550 IS - 9 M3 - Article N1 - Cited By :41 Export Date: 10 November 2020 PY - 2015 ST - Neutrophil responses to sterile implant materials T2 - PLoS ONE TI - Neutrophil responses to sterile implant materials UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84944755255&doi=10.1371%2fjournal.pone.0137550&partnerID=40&md5=d0742b10744b32e28948e64c459dab44 VL - 10 ID - 1220 ER - TY - JOUR AB - Neutrophil release and migration in mice were studied over a 24-hr period after the sc implantation of a single polyvinyl sponge. The release of neutrophils from the marrow was evaluated by directly counting the residual neutrophils in the femoral marrow of animals with sponges. Sponge and tissue neutrophil content was determined by extraction and assay of myeloperoxidase (MPO), a marker enzyme for neutrophils. A maximum depletion of 48% of the mature neutrophils in the marrow was observed 5 hr after sponge implantation, in keeping with significant release of neutrophils for migration to the sponge. The released cells were not found in the circulating granulocyte pool, since neutropenia was noted. The accumulation of neutrophils in the sponge increased throughout the 24-hr period, whereas in the tissue adjacent to the sponge maximum accumulation of neutrophils occurred within 7 hr. In fact, neutrophils migrated to at least three sites—the sponge, the skin overlying the sponge, and the skin in which an incision had been made to insert the sponge. The sponge content of neutrophils represented 0.3-33% of the neutrophils migrating to the combined lesion (sponge and skin sites). Therefore, if the neutrophil response to foreign body implantation is to be measured in its entirety, it is necessary to quantify not only the neutrophils within the foreign body but also those in the tissues surrounding it. These studies describe an animal model for neutrophil release and migration to tissues following a standard stimulus. It is proposed that this model may be useful in exploring the factors which influence the release and migration of neutrophils in vivo. © 1983, SAGE Publications. All rights reserved. AD - Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah 84132, United States AU - Priebat, D. A. AU - Bradley, P. P. AU - Christensen, R. D. AU - Rothstein, G. DB - Scopus DO - 10.3181/00379727-172-41523 IS - 1 M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 1983 SP - 39-45 ST - The Neutrophil Response to Polyvinyl Sponge Implantation T2 - Proceedings of the Society for Experimental Biology and Medicine TI - The Neutrophil Response to Polyvinyl Sponge Implantation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0020531734&doi=10.3181%2f00379727-172-41523&partnerID=40&md5=a79e76ec099953d385abfde92ab0381b VL - 172 ID - 1759 ER - TY - JOUR AB - PURPOSE. Retinal prosthetics have been designed to interface with the neural retina by electrically stimulating the remaining retinal circuits after photoreceptor degeneration. However, the electrical stimulation provided by the subretinal implant may also stimulate neurotrophic factors that provide neuroprotection to the retina. This study was undertaken to determine whether electrical stimulation from a subretinal photodiode-based implant has a neuroprotective effect on photoreceptors in the. RCS rat, a model of photoreceptor degeneration. METHODS. Eyes of RCS rats were implanted with an active or inactive device or underwent sham surgery before photoreceptor degeneration. Outer retinal function was assessed with electroretinogram (ERG) recordings weekly until 8 weeks after surgery, at which time retinal tissue was collected and processed for morphologic assessment, including photoreceptor cell counts and retinal layer thickness. RESULTS. At 4 to 6 weeks after surgery, the ERG responses in the active-implant eyes were 30% to 70% greater in b-wave amplitude than the response from eyes implanted with inactive devices those undergoing sham surgery, or the nonsurgical control eyes. At 8 weeks after surgery the ERG responses from active-implant eyes were not significantly different from the control groups. However, the number of photoreceptors in eyes implanted with the active or inactive device was significantly greater in the regions over and around the implant versus sham-surgical and non-surgical and nonsurgical control eyes. Conclusions: These results suggest that subretinal electrical stimulation provides temporary preservation of retinal function in the RCS rat. In addition, implantation of an active or inactive device into the subretinal space causes morphologic preservation of photoreceptors in the RCS rat until 8 weeks after surgery. Further studies are needed to determine whether the correlation of neuropreservation with subretinal implantation is due to electrical stimulation and/or a mechanical presence of the implant in the subretinal space. AD - Atlanta VA Medical Center, Decatur, GA, United States Department of Ophthalmology, Emory University, Atlanta, GA, United States Optobionics Corp., Naperville, IL, United States Cleveland VA Medical Center, Case Western Reserve University, Cleveland, OH, United States Research Service (151 Oph), Atlanta VA Medical Center, 1670 Clairmont Road, Decatur, GA 30033, United States AU - Pardue, M. T. AU - Phillips, M. J. AU - Yin, H. AU - Sippy, B. D. AU - Webb-Wood, S. AU - Chow, A. Y. AU - Ball, S. L. DB - Scopus DO - 10.1167/iovs.04-0515 IS - 2 M3 - Article N1 - Cited By :90 Export Date: 10 November 2020 PY - 2005 SP - 674-682 ST - Neuroprotective effect of subretinal implants in the RCS rat T2 - Investigative Ophthalmology and Visual Science TI - Neuroprotective effect of subretinal implants in the RCS rat UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-13944267454&doi=10.1167%2fiovs.04-0515&partnerID=40&md5=b1ac3a9d3740a7a8f17da92d3599b806 VL - 46 ID - 1613 ER - TY - JOUR AB - Implantable silicon microelectrode array technology is a useful technique for obtaining high-density, high-spatial resolution sampling of neuronal activity within the brain and holds promise for a wide range of neuroprosthetic applications. One of the limitations of the current technology is inconsistent performance in long-term applications. Although the brain tissue response is believed to be a major cause of performance degradation, the precise mechanisms that lead to failure of recordings are unknown. We observed persistent ED1 immunoreactivity around implanted silicon microelectrode arrays implanted in adult rat cortex that was accompanied by a significant reduction in nerve fiber density and nerve cell bodies in the tissue immediately surrounding the implanted silicon microelectrode arrays. Persistent ED1 up-regulation and neuronal loss was not observed in microelectrode stab controls indicating that the phenotype did not result from the initial mechanical trauma of electrode implantation, but was associated with the foreign body response. In addition, we found that explanted electrodes were covered with ED1/MAC-1 immunoreactive cells and that the cells released MCP-1 and TNF-α under serum-free conditions in vitro. Our findings suggest a potential new mechanism for chronic recording failure that involves neuronal cell loss, which we speculate is caused by chronic inflammation at the microelectrode brain tissue interface. AD - Keck Center for Tissue Engineering, Department of Bioengineering, University of Utah, Salt Lake City, UT 84112, United States Macromolecular Science and Engineering Center, Department of Materials Science and Engineering, University of Michigan, Ann Arbor, MI 48109, United States AU - Biran, R. AU - Martin, D. C. AU - Tresco, P. A. DB - Scopus DO - 10.1016/j.expneurol.2005.04.020 IS - 1 KW - Brain tissue Implantation Neuroinflammation Neurotoxicity Silicon M3 - Article N1 - Cited By :574 Export Date: 10 November 2020 PY - 2005 SP - 115-126 ST - Neuronal cell loss accompanies the brain tissue response to chronically implanted silicon microelectrode arrays T2 - Experimental Neurology TI - Neuronal cell loss accompanies the brain tissue response to chronically implanted silicon microelectrode arrays UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-23644450358&doi=10.1016%2fj.expneurol.2005.04.020&partnerID=40&md5=49b2d654b791e71b241690e1d7506b94 VL - 195 ID - 1600 ER - TY - JOUR AB - Thousands of patients with renal disease are on waiting lists for kidney transplant. Survival and quality of life on hemodialysis are much lower than that after renal transplantation. Renal allografts are extremely valuable and worth saving at all costs. Many complications can be seen after organ transplants on short and long term as rejection, vascular compromise, and infection. There are various reports on partial nephrectomy after renal transplant secondary to de novo masses in the renal allograft. Here, we present a case where we used radiofrequency bipolar sealer for partial nephrectomy for necrotic abscess of the renal allograft. We successfully saved the allograft with partial nephrectomy despite parenchymal infection and necrosis. © 2014 by the American Society for Artificial Internal. AD - Ankara Numune Teaching Hospital, General Surgery Clinic, Sihhiye, Ankara, Turkey AU - Yildiz, B. D. DB - Scopus DO - 10.1097/MAT.0000000000000066 IS - 3 KW - Partial nephrectomy radiofrequency renal transplantation M3 - Article N1 - Export Date: 10 November 2020 PY - 2014 SP - 358-360 ST - Nephron-saving surgery for abscess of renal allograft using radiofrequency bipolar sealer T2 - ASAIO Journal TI - Nephron-saving surgery for abscess of renal allograft using radiofrequency bipolar sealer UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84900410615&doi=10.1097%2fMAT.0000000000000066&partnerID=40&md5=dfc8511540a9ad7795cf852bac097a5c VL - 60 ID - 1289 ER - TY - JOUR AB - Introduction: GOSSYPIBOMA describes a mass within a patient's body comprising a cotton matrix surrounded by a foreign body granuloma due to retained pieces of gauze; is an infrequent surgical complication & serious surgical malpractice resulting from negligence. Either detected early due an exudative inflammatory reaction with the formation of an abscess or can present late as a mass due to aseptic fibrotic reaction to the cotton material. Case Report: First case was that of a 45 year old male presenting with pain abdomen & vomiting after an open cholecystectomy done 2 months back and on laparotomy a surgical sponge was retrieved from jejunal lumen. Second is a female patient 45 yr old who had fever and purulent discharge P/V 3 months after a vaginal hysterectomy and a gauze was found in the POD on opening the vaginal vault. Third was also a female 36 year old with pain in epigastrium, vomiting & occasional rise of temperature, following open cholecystectomy 3months back. After endoscopic confirmation of a foreign body a square size surgical sponge was removed from the duodenum via laparotomy. The fourth one being the most interesting one where a 29 yr old female after a LSCS for a twin pregnancy complained of mild lower abdominal pain and constipation and while she had been planned for a cholecystectomy and repair of a divarication of recti, an accidental injury to the small bowel during first umbilical trochar entry led to discovery of a surgical sponge in the bowel lumen partially obstructing it. Discussion: Despite all considerations during operation the incidence of retained foreign bodies following surgery has a reported rate of 0.01% to 0.001%, of which gossypibomas make up 70-80%; only a third being correctly diagnosed. Symptoms either relate to recurrence, occlusion or septic changes. With an infrequent incidence & frequent misdiagnosis, this surgical malpractice is easily avoidable by mere watchfulness of the surgeon and rest of the OT staff. Simply keeping the sponge count and thorough exploration of the operative field before & after the procedures and use of surgical textiles impregnated with radiological markers would not only spare the patient of unnecessary morbidity but also the surgeon of serious medicolegal consequences. Conclusion: Though a rarity it must be suspected in every post operative case presenting with pain, obstruction etc. once confirmed gossypiboma is best removed by open surgery though laparoscopic and percutaneous removal has been reported in few selected cases. AD - S. Patnaik, Shanti Memorial Hospital Pvt.Ltd, India AU - Patnaik, S. DB - Embase DO - 10.1007/s00464-016-4771-7 KW - marker human nightmare surgeon society case report American negligence surgical sponge pain cholecystectomy patient female malpractice vomiting cotton surgery laparotomy foreign body postoperative complication fever morbidity vaginal hysterectomy textile procedures diagnostic error foreign body granuloma occlusion intestine small intestine accidental injury constipation abdomen lower abdominal pain twin pregnancy abscess duodenum temperature inflammation male obstruction LA - English M3 - Conference Abstract N1 - L72236566 2016-04-13 PY - 2016 SN - 0930-2794 SP - S371 ST - Negligence to nightmare: Gossypiboma - case reports T2 - Surgical Endoscopy and Other Interventional Techniques TI - Negligence to nightmare: Gossypiboma - case reports UR - https://www.embase.com/search/results?subaction=viewrecord&id=L72236566&from=export http://dx.doi.org/10.1007/s00464-016-4771-7 VL - 30 ID - 412 ER - TY - JOUR AB - Stingray injuries are frequent, and although mostly benign, some can be life-threatening. We present the case of a 24-year-old man who suffered from a stingray attack in the Indian Ocean with a thoracic penetrating trauma, and its management. © 2017 Elsevier Inc. AD - Cardiovascular and Thoracic Surgery Department, Felix Guyon University Hospital, Saint-Denis, La Réunion, France AU - Mahjoubi, L. AU - Joyeux, A. AU - Delambre, J. F. AU - Rind, A. DB - Scopus DO - 10.1053/j.semtcvs.2017.02.005 IS - 2 KW - penetrating chest injuries stingray injuries thoracic trauma video-assisted thoracoscopy surgery M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2017 SP - 262-263 ST - Near-death Thoracic Trauma Caused by a Stingray in the Indian Ocean T2 - Seminars in Thoracic and Cardiovascular Surgery TI - Near-death Thoracic Trauma Caused by a Stingray in the Indian Ocean UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017173372&doi=10.1053%2fj.semtcvs.2017.02.005&partnerID=40&md5=be5a6709dda20ef70d24348fb4e8d41d VL - 29 ID - 1144 ER - TY - JOUR AB - Retained surgical sponge is an infrequently reported condition that may be recognized incidentally during the early postoperative period, produce serious complications, or remain dormant for years. Clinical manifestations of the retained surgical sponge are a function of bacterial contamination and of the location of the sponge within the body cavity. Few sequelae follow external extrusion but internal erosion may lead to abscess, fistulas, and intestinal obstruction. Prevention requires constant sensitivity of the surgeon to this potential threat to the safe practice of surgery. The surgeon must account for an incorrect sponge count by adequate examination of the operative field and by roentgenographic studies when the issue remains in doubt. A correct sponge count does not fully preclude a retained sponge, however, and inspection of the operative field should be routine in all patients at risk. AN - 7089613 AU - Hyslop, J. W. AU - Maull, K. I. DA - Jun DO - 10.1097/00007611-198206000-00006 DP - NLM ET - 1982/06/01 IS - 6 KW - Bacterial Infections/etiology Female Humans Intestinal Obstruction/etiology Intraoperative Complications/prevention & control Male Malpractice Middle Aged Radiography, Abdominal *Surgical Equipment Surgical Procedures, Operative/*adverse effects LA - eng N1 - Hyslop, J W Maull, K I Case Reports Journal Article United States South Med J. 1982 Jun;75(6):657-60. doi: 10.1097/00007611-198206000-00006. PY - 1982 SN - 0038-4348 (Print) 0038-4348 SP - 657-60 ST - Natural history of the retained surgical sponge T2 - South Med J TI - Natural history of the retained surgical sponge VL - 75 ID - 6 ER - TY - JOUR AN - 104462286. Language: English. Entry Date: 20120720. Revision Date: 20150818. Publication Type: Journal Article AU - McNamara, Sharon A. DB - ccm DO - 10.1016/j.aorn.2012.03.015 DP - EBSCOhost IS - 6 KW - Anniversaries and Special Events -- History AORN Patient Safety Perioperative Nursing Treatment Errors -- Prevention and Control Communication Human Human Error Leadership Learning Medication Errors -- Prevention and Control Organizational Culture Patient Centered Care Patient Identification Retained Instruments -- Prevention and Control Surgical Count Procedure Surgical Site Verification Teamwork United States Wrong Site Surgery -- Prevention and Control N1 - research; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 0372403. PMID: NLM22633386. PY - 2012 SN - 0001-2092 SP - 805-814 ST - National Time Out Day: More Than 'a Pause and a Checklist' T2 - AORN Journal TI - National Time Out Day: More Than 'a Pause and a Checklist' UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104462286&site=ehost-live&scope=site VL - 95 ID - 751 ER - TY - JOUR AB - Objective: To get a clear view of the current state of treatment for esophageal perforation in Japan. Summary background data: Esophagus perforations are the most serious gastrointestinal tract perforations and are associated with high morbidity and mortality. The optimal treatment choice remains unknown. Methods: We conducted a retrospective clinical review of 182 esophageal perforation cases at 108 hospitals accredited by the Japanese Esophageal Society between January 2010 and December 2015. Results: We found that 20.9% of patients were incorrectly diagnosed initially. We observed mediastinum emphysema in 83.5% of patients, and serious abscess formations of the mediastinum and intrathoracic cavity in 38.6% and 29.6%, respectively. The lower esophagus was the most commonly perforated site (77.7%). Management of esophageal perforations included nonoperative treatment in 20 patients (11%) and operative treatment in 162 patients (89%). The overall mortality rate was 6.9%. The survivors had significantly shorter times from symptom appearance to visit (p = 0.0016), and from time to visit to diagnosis confirmation (p = 0.0011). Moreover, patients older than 65 years, white blood cells less than 3000/mm3, C-reactive protein > 10 mg/L, or abscesses in the thoracic cavity showed significantly higher mortality than others. Conclusion: Shortening the time from onset to the start of treatment contributes to reduce mortality in patients with esophageal perforation. Moreover, strict medical treatment is necessary to lower the mortality rate of elderly patients with strong inflammation and abscesses in the thoracic cavity. © 2020, The Japan Esophageal Society. AD - Department of General Surgical Science, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan Division of Gastro-Intestinal Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan Department of Gastroenterological Surgery, National Kyushu Cancer Center, Fukuoka, Japan Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Japan AU - Sohda, M. AU - Kuwano, H. AU - Sakai, M. AU - Miyazaki, T. AU - Kakeji, Y. AU - Toh, Y. AU - Matsubara, H. DB - Scopus DO - 10.1007/s10388-020-00744-7 IS - 3 KW - Esophageal perforation Survey M3 - Article N1 - Export Date: 10 November 2020 PY - 2020 SP - 230-238 ST - A national survey on esophageal perforation: study of cases at accredited institutions by the Japanese Esophagus Society T2 - Esophagus TI - A national survey on esophageal perforation: study of cases at accredited institutions by the Japanese Esophagus Society UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85084732327&doi=10.1007%2fs10388-020-00744-7&partnerID=40&md5=11b5ab970b6d6bd9f498470e1e413ce9 VL - 17 ID - 961 ER - TY - JOUR AB - Soft tissue losses from tumor removal, trauma, aging, and congenital malformation affect millions of people each year. Existing options for soft tissue restoration have several drawbacks: Surgical options such as the use of autologous tissue flaps lead to donor site defects, prosthetic implants are prone to foreign body response leading to fibrosis, and fat grafting and dermal fillers are limited to small-volume defects and only provide transient volume restoration. In addition, large-volume fat grafting and other tissue-engineering attempts are hampered by poor vascular ingrowth. Currently, there are no off-the-shelf materials that can fill the volume lost in soft tissue defects while promoting early angiogenesis. Here, we report a nanofiber-hydrogel composite that addresses these issues. By incorporating interfacial bonding between electrospun poly(-caprolactone) fibers and a hyaluronic acid hydrogel network, we generated a composite that mimics the microarchitecture and mechanical properties of soft tissue extracellular matrix. Upon subcutaneous injection in a rat model, this composite permitted infiltration of host macrophages and conditioned them into the pro-regenerative phenotype. By secreting pro-angiogenic cytokines and growth factors, these polarized macrophages enabled gradual remodeling and replacement of the composite with vascularized soft tissue. Such host cell infiltration and angiogenesis were also observed in a rabbit model for repairing a soft tissue defect filled with the composite. This injectable nanofiber-hydrogel composite augments native tissue regenerative responses, thus enabling durable soft tissue restoration outcomes. Copyright © 2019 The Authors AD - Translational Tissue Engineering Center, Johns Hopkins School of Medicine, Baltimore, MD 21287, United States Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD 21218, United States Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD 21218, United States Department of Plastic and Reconstructive Surgery, Johns Hopkins School of Medicine, Baltimore, MD 21287, United States Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD 21205, United States Mary and Dick Holland Regenerative Medicine Program, Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE 68198, United States AU - Li, X. AU - Cho, B. AU - Martin, R. AU - Seu, M. AU - Zhang, C. AU - Zhou, Z. AU - Choi, J. S. AU - Jiang, X. AU - Chen, L. AU - Walia, G. AU - Yan, J. AU - Callanan, M. AU - Liu, H. AU - Colbert, K. AU - Morrissette-McAlmon, J. AU - Grayson, W. AU - Reddy, S. AU - Sacks, J. M. AU - Mao, H. Q. C7 - eaau6210 DB - Scopus DO - 10.1126/scitranslmed.aau6210 IS - 490 M3 - Article N1 - Cited By :27 Export Date: 10 November 2020 PY - 2019 ST - Nanofiber-hydrogel composite–mediated angiogenesis for soft tissue reconstruction T2 - Science Translational Medicine TI - Nanofiber-hydrogel composite–mediated angiogenesis for soft tissue reconstruction UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065549441&doi=10.1126%2fscitranslmed.aau6210&partnerID=40&md5=d5d82f18476d10b007be2f610da88900 VL - 11 ID - 1017 ER - TY - JOUR AB - Nail punctures through rubber-soled shoes expose the foot to the possibility of deep infection and foreign body retention. In this article, we describe characteristics of adult patients who sustained nail puncture wounds through a rubber-soled shoe and were treated at our institution from January 1, 2000, to January 8, 2008. Of the 96 patients, 36 (37.5%) were treated conservatively and 60 (62.5%) were treated surgically in the operating room. Of those treated surgically, 15 (25%) had a foreign body extracted during the operation. The operated group had a longer duration of time from injury to hospital admission than did the nonoperated group (5.0 +/- 6.8 days versus 2.7 +/- 3.8 days, P < .05). Treatment success was observed in 91 (94.8%) of the patients, and the median lag time before admission for the less successfully treated group was longer than that for the successfully treated group (10 days versus 2 days, P < .002); and, the less successfully treated group was more likely to receive antibiotics in the community before hospitalization (100.0% versus 47.2%, P < .06), and was more likely to be diabetic (40.0% versus 9.9%, P < .10). Fever, white blood cell count, and erythrocyte sedimentation rate were not significantly associated with treatment outcome. Success of the treatment did not depend on white blood cell count, erythrocyte sedimentation rate, or fever. Ultrasonography was useful in detecting the presence of a foreign body. AD - Orthopaedic Department, Central Emek Hospital, Afula, Israel. guytalr@bezeqint.net AN - 20797584 AU - Rubin, G. AU - Chezar, A. AU - Raz, R. AU - Rozen, N. DA - Sep-Oct DO - 10.1053/j.jfas.2010.06.017 DP - NLM ET - 2010/08/28 IS - 5 KW - Adolescent Adult Aged Anti-Bacterial Agents/therapeutic use Blood Sedimentation Cohort Studies Diabetes Mellitus/epidemiology Female Fever/diagnosis Foot Injuries/diagnosis/*therapy Foreign Bodies/*complications/diagnostic imaging/surgery Humans Leukocyte Count Male Middle Aged Retrospective Studies *Rubber *Shoes Soft Tissue Infections/microbiology Time Factors Treatment Outcome Ultrasonography Wounds, Penetrating/diagnosis/*therapy LA - eng N1 - 1542-2224 Rubin, Guy Chezar, Avi Raz, Raul Rozen, Nimrod Journal Article United States J Foot Ankle Surg. 2010 Sep-Oct;49(5):421-5. doi: 10.1053/j.jfas.2010.06.017. PY - 2010 SN - 1067-2516 SP - 421-5 ST - Nail puncture wound through a rubber-soled shoe: a retrospective study of 96 adult patients T2 - J Foot Ankle Surg TI - Nail puncture wound through a rubber-soled shoe: a retrospective study of 96 adult patients VL - 49 ID - 100 ER - TY - JOUR AB - Background. Nafamostat mesilate (FUT-175) is a synthetic serine protease inhibitor that inactivates coagulation, fibrinolysis, and platelet aggregation. Nafamostat mesilate may suppress the blood-foreign surface reaction similar to biocompatible materials by blocking factor XIIa. Methods. We performed an in vitro study of cardiopulmonary bypass (CPB) with fresh human blood among the following three groups: standard CPB sets (C), biocompatible CPB sets (B), and standard CPB sets with FUT-175 (10 mg/L) (F). A clinical study using these same CPB groups also was performed in 45 patients undergoing aortocoronary bypass operations (15 patients each). We injected FUT-175 at 40 mg/h during CPB. Results. In the in vitro study, both groups B and F showed significantly lower levels of coagulation factors, thrombin-antithrombin III complex, fibrinopeptide A, β-thromboglobulin, complement C3a, granulocyte elastase, and free hemoglobin than group C at the conclusion of the study. Thrombin-antithrombin III complex and free hemoglobin in group F also were lower than in group B. The platelet count remained at a higher level in group F than in the other groups. Separation of bradykinin was suppressed most significantly in group F. In the clinical study, group F also showed significantly lower levels of α2-plasmin inhibitor plasmin complex and C3a than both groups C and B. There were minimal levels of free hemoglobin in group F. Conclusions. Nafamostat mesilate may contribute major beneficial effects toward conservation of blood during CPB and prevention of coagulopathy after CPB. AD - A. Usui, 2-903 Umegaoka, Tenpaku-ku, Nagoya 468, Japan AU - Usui, A. AU - Hiroura, M. AU - Kawamura, M. AU - Hibi, M. AU - Yoshida, K. AU - Murakami, F. AU - Tomita, Y. AU - Ooshima, H. AU - Murase, M. C1 - fut 175(Torii,Japan) C2 - Torii(Japan) DB - Embase Medline DO - 10.1016/0003-4975(96)00634-0 IS - 5 KW - nafamstat mesilate proteinase inhibitor adult aged article biocompatibility blood storage cardiopulmonary bypass clinical article clinical trial controlled clinical trial controlled study coronary artery bypass graft female fibrinolysis foreign body human human cell male priority journal randomized controlled trial fut 175 LA - English M3 - Article N1 - L26383541 1996-12-04 PY - 1996 SN - 0003-4975 SP - 1404-1411 ST - Nafamostat mesilate reduces blood-foreign surface reactions similar to biocompatible materials T2 - Annals of Thoracic Surgery TI - Nafamostat mesilate reduces blood-foreign surface reactions similar to biocompatible materials UR - https://www.embase.com/search/results?subaction=viewrecord&id=L26383541&from=export http://dx.doi.org/10.1016/0003-4975(96)00634-0 VL - 62 ID - 666 ER - TY - JOUR AB - Background: This study aimed to observe the relationship between the number of myofibroblasts, the tensile strength of the breast implant capsule, and the degree of breast capsular contracture. Methods: The study enrolled 21 women with 31 capsular contractures after aesthetic breast augmentation. The capsular tissue specimens were obtained during capsulectomy, open capsulotomy, and other revisional procedures. The tensile strength of capsular tissues (1 × 3 cm) was measured by tensiometer. The capsular tissues were immunostained by alpha smooth muscle actin, and the immunostained myofibroblasts all were counted on a 2.5-mm length of the capsule. Results: Myofibroblasts were detected in 22 (71%) of 31 specimens. The myofibroblasts were on the outer layer of the capsule and made up 7.3% to 50% (average, 26.9% ± 12.7%) of the capsule thickness. The number of myofibroblasts varied according to the degree of capsular contracture, but grades 2, 3, and 4 contracture did not differ significantly (p = 0.102). The average tensile strength of the capsule was 44 ± 38 N. Tensile strength was the lowest for grade 2 (27.0 ± 22.2 N), increased for grade 3 (38.0 ± 22.6 N), and was highest for grade 4 (66.5 ± 55.4 N; p = 0.044) contracture. The tensile strength of the capsule correlated positively with the degree of capsular contracture (p = 0.029). Conclusion: The tensile strength of breast capsules correlated with the degree of capsular contracture. The authors think myofibroblasts appear during an active phase of wound contraction and diminish when the wound has matured. © 2010 Springer Science+Business Media, LLC and International Society of Aesthetic Plastic Surgery. AD - Department of Plastic Surgery, Center for Advanced Medical Education by the BK21 Project, Inha University School of Medicine, 7-206 Sinheung-dong, Jung-gu, Incheon 400-711, South Korea Baram Breast and Body Center, Seoul, South Korea Department of Anatomy, Center for Advanced Medical Education by the BK21 Project, Inha University School of Medicine, Incheon, South Korea AU - Hwang, K. AU - Sim, H. B. AU - Huan, F. AU - Kim, D. J. DB - Scopus DO - 10.1007/s00266-010-9532-8 IS - 6 KW - Breast implantation Contracture Fibroblasts Tensile strength M3 - Article N1 - Cited By :44 Export Date: 10 November 2020 PY - 2010 SP - 716-721 ST - Myofibroblasts and capsular tissue tension in breast capsular contracture T2 - Aesthetic Plastic Surgery TI - Myofibroblasts and capsular tissue tension in breast capsular contracture UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-78651089128&doi=10.1007%2fs00266-010-9532-8&partnerID=40&md5=3d00fe38dfead8e5777201e2c2080c37 VL - 34 ID - 1441 ER - TY - JOUR AB - Mycobacterium avium complex is a rare cause of musculoskeletal infection, usually occurring in patients with compromised immune systems. Obtaining the diagnosis requires a high index of suspicion, and treatment can be delayed because of difficulty with isolating the organism. Treatment involves prolonged, targeted combination antibiotic therapy, and it is unclear whether eradication of the infection can occur in the presence of a foreign body, such as antibiotic spacers. The authors report a case of M avium infection presenting as presumed osteonecrosis of the femoral head in a young woman with systemic lupus erythematosus. She presented with collapse of her femoral head coinciding with several months of progressive, debilitating hip pain. She had mild fevers during that time, but results from multiple infectious workups, including hip aspiration, were negative. Purulent fluid was found in the operating room, but diagnosis was delayed for 5 weeks while waiting for cultures. The patient required 3 subsequent operations, eventually being left with a resection arthroplasty. Pertinent issues concerning diagnosis, therapy, and treatment challenges in M avium infections of the musculoskeletal system are discussed in this case report. © SLACK Incorporated. AD - Hospital for Special Surgery, 535 E 70th St, New York, NY 10021, United States New York Presbyterian-Weill Cornell Medical College, New York, NY, United States AU - Christ, A. B. AU - Zininberg, E. V. AU - Jules-Elysee, K. M. AU - Parks, M. L. DB - Scopus DO - 10.3928/01477447-20161229-04 IS - 3 M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2017 SP - e549-e552 ST - Mycobacterium avium complex septic arthritis presenting as osteonecrosis of the femoral head in a patient with systemic lupus erythematosus T2 - Orthopedics TI - Mycobacterium avium complex septic arthritis presenting as osteonecrosis of the femoral head in a patient with systemic lupus erythematosus UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85020195337&doi=10.3928%2f01477447-20161229-04&partnerID=40&md5=572a8071c340bfd0d803cebecbeccd1f VL - 40 ID - 1136 ER - TY - JOUR AB - Objective It has been reported previously that granulomas can occur around nonabsorbable sutures, but that granuloma formation around the staple line is very rare. However, the increased use of thoracoscopic surgery is creating more opportunities to use automatic mechanical suturing equipment for pulmonary surgery, and it is expected that the incidence of granuloma around the staple line will increase. Methods We retrospectively investigated the clinical records of 6 patients who developed nontuberculous mycobacterial granuloma on the staple line after pulmonary resection. We investigated their clinical characteristics and compared them with data in 16 cases of cancer recurrence. Results Fluorodeoxyglucose uptake was detected in all 6 patients. Laboratory data including white blood cell counts and C-reactive protein levels were within normal ranges in all patients. There was no evident tendency in terms of age, sex, maximal standardized uptake value, or radiological findings. However, compared to cancer recurrence, mycobacterial granuloma around the staple line appeared after a longer period of time, and the proportion of patients who had a segmentectomy as the initial surgery was significantly higher. Conclusion When growing shadows are observed near the staple line, it is difficult to differentiate between cancer recurrence and nontuberculous mycobacterial granuloma from computed tomography and laboratory findings. However, if a mass shadow around the staple line appears 2, 3, or more years after segmentectomy, it could be considered likely to be a granuloma. "Post-segmentectomy" and "late occurrence" are important attributes for distinguishing staple line granuloma from cancer recurrence. AD - Department of Thoracic Surgery, National Hospital Organization Himeji Medical Center, Himeji-City, Hyogo, Japan. AN - 30185073 AU - Matsuoka, K. AU - Ueda, M. AU - Miyamoto, Y. DA - Sep DO - 10.1177/0218492318798228 DP - NLM ET - 2018/09/07 IS - 7 KW - Aged Female Follow-Up Studies Granuloma/diagnosis/*microbiology Humans Lung Neoplasms/surgery Male Middle Aged Mycobacterium Infections, Nontuberculous Nontuberculous Mycobacteria/*isolation & purification Pneumonectomy/*adverse effects Retrospective Studies Surgical Stapling/*adverse effects Surgical Wound Infection/diagnosis/*microbiology Sutures/adverse effects/*microbiology Thoracic Surgery, Video-Assisted/methods Time Factors Tomography, X-Ray Computed Granuloma Lung neoplasms Mycobacterium Pneumonectomy Surgical staplers Thoracic surgery foreign-body video-assisted LA - eng N1 - 1816-5370 Matsuoka, Katsunari Ueda, Mitsuhiro Miyamoto, Yoshihiro Journal Article England Asian Cardiovasc Thorac Ann. 2018 Sep;26(7):540-545. doi: 10.1177/0218492318798228. Epub 2018 Sep 5. PY - 2018 SN - 0218-4923 SP - 540-545 ST - Mycobacterial granuloma on the staple line after pulmonary resection T2 - Asian Cardiovasc Thorac Ann TI - Mycobacterial granuloma on the staple line after pulmonary resection VL - 26 ID - 219 ER - TY - JOUR AB - Introduction: The incidental detection of multiple pulmonary nodules in a smoking patient is highly suspicious for the presence of malignant disease of either pulmonary or metastatic origin. However, pulmonary nodules can also be seen in non-malignant extrapulmonary diseases including inflammatory bowel disease. Case presentation: A 46-year old patient was referred after the detection of multiple pulmonary nodules in both lower lung lobes in an abdominal computed tomography (CT) scan performed for the investigation of frequent loose stools (Figure 1). The patient had a smoking history of 20 pack years and was otherwise healthy. He complained of temperatures of around 37.2° Celsius, night sweats and weakness. Symptoms started six weeks prior to admission and did not respond to antibiotics. Upon presentation, the patient was alert and in no distress. Abdominal examination and chest auscultation were unremarkable. Positron emission tomography (PET) scan showed an elevated uptake with a standardized uptake value (SUV) of 4.6. Pulmonary function tests and arterial blood gas analysis were normal. Bronchoscopy with brushings was non-diagnostic. Bronchoalveolar lavage (BAL) revealed normal total- and differential cell counts. A transthoracic biopsy showed foreign-body type granuloma and intraalveolar fibroblasts, consistent with organizing pneumonia (Figure 2). Colonoscopy revealed pancolitis without terminal ileitis. Biopsies of the colonic mucosa showed changes compatible with ulcerative colitis (UC). The diagnosis of organizing pneumonia (OP) in the context of UC was retained. A therapy with mesalazin was started and the patient's bowel symptoms resolved rapidly. However, he still complained of subfebrile temperatures, weakness and night sweats. Even though no functional impairment induced by OP was found, a course of systemic steroids was started. One week later, the patient was free of symptoms. Discussion: UC is an inflammatory bowel disease usually limited to the colon mucosa. However, extraintestinal manifestations are well described and include also lung disease. Airway involvement is mostly seen and often presents as chronic cough, mucoid impaction, bronchial obstruction and bronchiectasis. OP in the context of UC has been described before in a few case reports, but seems to be a rare entity with the last publication dating back to 2003. Furthermore, pulmonary manifestations of UC usually appear years after diagnosis, unlike in this case. AD - L. Kern, Cantonal Hospital St. Gallen, St. Gallen, Switzerland AU - Kern, L. AU - Rüdiger, J. AU - Meyenberger, C. AU - Rodriguez, R. AU - Brutsche, M. H. DB - Embase DO - 10/1159/000327394 IS - 1 KW - steroid antibiotic agent society multiple pulmonary nodules otorhinolaryngology smoking head and neck surgery thorax surgery patient human diagnosis enteritis organizing pneumonia temperature night sweat weakness colon mucosa lung disease airway bronchus obstruction bronchiectasis case report lung nodule lung lobe computer assisted tomography loose feces examination thorax auscultation positron emission tomography lung function test arterial gas blood gas analysis coughing lung lavage leukocyte differential count transthoracic biopsy foreign body granuloma fibroblast colonoscopy bronchoscopy ileitis biopsy ulcerative colitis therapy intestine functional disease LA - English M3 - Conference Abstract N1 - L70494354 2011-08-17 PY - 2011 SN - 0025-7931 SP - 96-97 ST - Multiple pulmonary nodules in a smoker - Got it? T2 - Respiration TI - Multiple pulmonary nodules in a smoker - Got it? UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70494354&from=export http://dx.doi.org/10/1159/000327394 VL - 82 ID - 539 ER - TY - JOUR AB - Background: Medical devices are an essential part of modern health-care, but its usage has led to the emergence of medical device associated infections otherwise known as Foreign-Body related infections (FBRIs). This is caused by bacterial adhesion and biofilm formation on their surfaces which act as a nidus of infection. These biofilms are resistant to antibacterial agents and host immune response. The antibiotics which are useful in treating planktonic forms cannot clear the biofilm and the device must usually be removed to resolve the infection. Objective: The main objective of the study was to identify the prevalence of bacterial biofilms on retrieved catheters which included vascular catheters (141) and Foley catheters (86) from patients and understand the nature of antibiotic resistant strains in these biofilms. Materials used: 227 numbers of retrieved catheters which included vascular catheters (141nos) and Foley catheters (86 nos) were used in the study. These retrieved implants were from patients from neurosurgery ward of SCTIMST who had undergone selective neurosurgical procedures. Patients with pre-existing infections including brain abscess were not included in the study. These patients had no clinical infection or pyrexia. Skin swabs were taken from patients using intravascular devices after retrieval of catheter. Results and Conclusions: Among vascular catheters Staphylococcus species were the major isolate and among the isolates many of the strains were Methicillin and some were Vancomycin resistant. Among the Foley catheter isolates E. faecalis was the major isolate followed by E. coli, Staphylococcus species, Klebsiella species, Pseudomonas species, Citrobacter etc. Most of the strains were resistant to multiple antibiotics. Although the patients selected did not have any clinical symptoms of infection, the presence of multiple-drug resistant organisms as biofilm points to this niche which can constitute a threat for HAIs and its resultant complications. This suggests that catheters should be removed as early as possible to prevent Biofilm development on them. © JAPI. AD - Division of Microbiology, BMT Wing, India Neurosurgery Department, India Division of Microbiology, BMT Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology TVPM, Kerala, India AU - Pradeep Kumar, S. S. AU - Easwer, H. V. AU - Maya Nandkumar, A. DB - Scopus IS - OCT M3 - Article N1 - Cited By :12 Export Date: 10 November 2020 PY - 2013 SP - 702-707 ST - Multiple Drug Resistant Bacterial Biofilms on Implanted Catheters - A Reservoir of Infection T2 - Journal of Association of Physicians of India TI - Multiple Drug Resistant Bacterial Biofilms on Implanted Catheters - A Reservoir of Infection UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84884678404&partnerID=40&md5=69fe3e8f3ff13b80efaeb341b7c1ce97 VL - 61 ID - 1308 ER - TY - JOUR AN - 105448153. Language: English. Entry Date: 20090227. Revision Date: 20150818. Publication Type: Journal Article AU - Denholm, B. DB - ccm DP - EBSCOhost KW - Needles Surgical Count Procedure N1 - brief item; questions and answers. Supplement Title: Dec2007 Supplement. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2007 SN - 0001-2092 SP - S119-S119 ST - Multipack needle counts T2 - AORN Journal TI - Multipack needle counts UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105448153&site=ehost-live&scope=site VL - 86 ID - 882 ER - TY - JOUR AB - Background: Retained foreign objects (RFOs) after surgical procedures are an infrequent but potentially devastating medical error. The Mayo Clinic, Rochester (MCR), undertook a quality improvement program to reduce the incidence of surgical RFOs.Method: A multidisciplinary, multiphase approach was initiated in 2005. The effort, led by surgical, nursing, and administrative institutional leaders, was divided into three phases. The first phase included a defect analysis and policy review. A detailed analysis of all RFOs (both true and near misses) was undertaken to identify patterns of failures unique to our institution and operating room culture. Simultaneously, a review of all relevant institutional policies was performed, with comprehensive revisions focusing on increased clarity and inter- and intrapolicy consistency. The second phase involved increasing awareness and communication among all operating room personnel, including surgeons, residents, nursing, and allied health staff. The education program included all-staff conferences, team training, simulation videos, and daily education reminders and in-room audits. Finally, a monitoring and control phase involved rapid leadership response teams to any events, enhanced staff communication, and policy reviews.Results: When the program started, MCR was averaging a surgical RFO every 16 days. After the intervention, the average interval between RFO events increased to 69 days, a level of performance that has been sustained for more than two years.Discussion: MCR experienced a significant and sustained reduction in the incidents of RFOs, attributed to the multidisciplinary nature of the initiative, the active engagement of institutional leadership, and use of the principles of enhanced communication between operating room staff members to improve operating room situational awareness. AD - Department of Surgery, Mayo Clinic, Rochester, Minnesota, cima.robert@mayo.edu AN - 105469418. Language: English. Entry Date: 20090501. Revision Date: 20150711. Publication Type: Journal Article AU - Cima, R. R. AU - Kollengode, A. AU - Storsveen, A. S. AU - Weisbrod, C. A. AU - Deschamps, C. AU - Koch, M. B. AU - Moore, D. AU - Pool, S. R. DB - ccm DP - EBSCOhost IS - 3 KW - Multidisciplinary Care Team Quality Improvement Retained Instruments -- Prevention and Control Accountability Audit Communication Decision Making, Clinical Documentation Incidence Leadership Meetings Operating Room Personnel Posters -- Utilization Protocols Retained Instruments -- Epidemiology Staff Development Surgical Count Procedure Videorecording Human N1 - algorithm; pictorial; research; tables/charts. Journal Subset: Editorial Board Reviewed; Expert Peer Reviewed; Health Services Administration; Peer Reviewed; USA. NLM UID: 101238023. PY - 2009 SN - 1553-7250 SP - 123-132 ST - A multidisciplinary team approach to retained foreign objects T2 - Joint Commission Journal on Quality & Patient Safety TI - A multidisciplinary team approach to retained foreign objects UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105469418&site=ehost-live&scope=site VL - 35 ID - 855 ER - TY - JOUR AB - Introduction: Foreign body (FB) aspiration is typically observed in children, with 75-85% of cases occurring before age fifteen. The presence of airway foreign bodies in adults is usually associated with compromised airway protection mechanisms. We present an adult with an obstructing FB in his right main-stem bronchus (RMB), which was removed with flexible bronchoscopy by operating under a multi-disciplinary approach. Case Report: A 64-year old man with human immunodeficiency virus (CD4 count 232) presented with six months of cough exacerbated by swallowing, but denied aspiration of food or foreign objects. Physical exam: normal. Laboratory values: WBC 8.2x10∧3/uL with a normal differential. Chest CT: large obstructing high density FB in RMB. Clinical course: Endotracheal tube (ETT) was placed for flexible bronchoscopy. A cylindrical FB (Figure) was identified in the RMB and grasped with large rat tooth forceps, but dislodged within the trachea. Attempts to remove the FB were made with a variety of instruments (balloon catheter, net basket and cryoprobe). Though initially successful, these efforts ultimately failed due to the object's dimensions. The FB moved proximally causing tracheal obstruction, hypoxemia and pulseless electrical activity arrest. To relieve the tracheal obstruction, the FB was pushed distally into the left main-stem bronchus and the patient was resuscitated. Thoracic surgery assistance with rigid bronchoscopy was requested. Rigid forceps via rigid bronchoscope could not maintain reliable grasp of the FB. Flexible bronchoscopy via ETT demonstrated the FB in the trachea at a more advantageous angle, enabling stable grasp with large rat tooth forceps. Simultaneous withdrawal of the bronchoscope, ETT and FB resulted in successful removal. The FB was a plastic pill bottle desiccant measuring 1.5x2cm. Patient was transferred to the intensive care unit and subsequently discharged home. Discussion: This case highlights the difficulties of removing a large aspirated FB, particularly when the exact shape and dimensions are unknown. Bronchoscopy revealed a large cylindrical FB initially not amenable to standard modalities of removal. Although clinical instability led to use of rigid bronchoscopy, success was ultimately achieved with flexible bronchoscopy. The potential for tracheal or glottic obstruction during removal increases with widened FB diameter. This case emphasizes the need for cautious protection of the airway, which allows for experimentation of different techniques until identification of a successful approach. A coordinated, multi-disciplinary approach in a controlled environment led to removal of this FB. (Figure Presented). AD - N. Siegel, Icahn School of Medicine at Mount Sinai, New York, NY, United States AU - Siegel, N. AU - Ortega, A. AU - Kaufman, A. AU - DiFabrizio, L. AU - Harkin, T. J. DB - Embase KW - desiccant CD4 antigen plastic American society foreign body bronchoscopy human forceps airway trachea obstruction bronchus rat trachea patient tooth adult protection aspiration Human immunodeficiency virus endotracheal tube disease course density rigid bronchoscope bronchoscope male case report thorax hypoxemia laboratory food cryoprobe swallowing balloon catheter electric activity coughing thorax surgery pill child intensive care unit obstruction microclimate foreign body aspiration LA - English M3 - Conference Abstract N1 - L72046391 2015-11-05 PY - 2014 SN - 1073-449X ST - A multi-disciplinary approach to foreign body removal T2 - American Journal of Respiratory and Critical Care Medicine TI - A multi-disciplinary approach to foreign body removal UR - https://www.embase.com/search/results?subaction=viewrecord&id=L72046391&from=export http://www.atsjournals.org/doi/pdf/10.1164/ajrccm-conference.2014.189.1_MeetingAbstracts.A4440 VL - 189 ID - 443 ER - TY - JOUR AB - Gossypiboma is a mass-like lesion due to retained cotton swab in abdominal cavity following any operation or exploratory procedure. It is not very uncommon, occurring in about 1 in 1500 operations worldwide. It can either become a fibrotic nodular mass or develop into an abscess. Here we describe abscess formed following gossypiboma development in a young female following Caesarian section which was done in a private hospital. AD - Department of Microbiology, All India Institute of Medical Sciences, Patna, Bihar, 801105, India Department of General Surgery, All India Institute of Medical Sciences, Patna, Bihar, 801105, India AU - Ansari, M. A. A. AU - Bhattacharyya, S. AU - Sarfraz, A. AU - Jaiswal, N. K. AU - Kumar, M. DB - Scopus IS - 5 KW - Escherichia coli Gossypiboma Multi drug resistant M3 - Article N1 - Export Date: 10 November 2020 PY - 2014 SP - 1137-1139 ST - Multi drug resistant escherichia coli forming intra-abdominal abscess in a case of gossypiboma: Case report and review of literature T2 - Research Journal of Pharmaceutical, Biological and Chemical Sciences TI - Multi drug resistant escherichia coli forming intra-abdominal abscess in a case of gossypiboma: Case report and review of literature UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84907143257&partnerID=40&md5=3164e6ad71becd93905ee6ae9dc2796d VL - 5 ID - 1290 ER - TY - JOUR AB - Rubber band syndrome is caused by constriction of the wrist from elastic bracelets worn for decorative purposes. Overtime, the fixed or elastic band burrows into the skin and becomes invisible. We present the case of a 2.5-year-old female child presenting to our institution with signs of circumferential swelling and inflammatory changes about the right wrist. MRI of the wrist demonstrated a subcutaneous circular foreign body, which was confirmed at surgery to be a rubber band. Although this disease entity is rare, radiologists can be instrumental in suggesting this diagnosis based on the location involved, ie, wrist, and the imaging findings. © 2020 AD - Department of Radiology, McFarland Clinic, Ames, IA, United States Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States Mayo Clinic, Department of Radiology, 200 First Street SW, Rochester, MN 55905, United States Department of Orthopedics and Physical Medicine, Medical University of South Carolina, Charleston, SC, United States Shriners Hospitals for Children, Springfield, MA, United States AU - Sosnouski, D. AU - Chapin, R. W. AU - Thacker, P. G. AU - Walton, Z. J. AU - Mooney, J. F. DB - Scopus DO - 10.1016/j.radcr.2020.04.039 IS - 7 KW - Bracelet Children MRI Rubber band Wrist M3 - Article N1 - Export Date: 10 November 2020 PY - 2020 SP - 999-1001 ST - MRI diagnosis of rubber band constriction syndrome T2 - Radiology Case Reports TI - MRI diagnosis of rubber band constriction syndrome UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85084496023&doi=10.1016%2fj.radcr.2020.04.039&partnerID=40&md5=02059195c844796b64e75b72e1783c25 VL - 15 ID - 959 ER - TY - JOUR AB - The use of bioabsorbable polymers in (bio)medical applications has increased greatly in recent years, mainly because of their good bioreabsorption and biocompatibility. In this work, we examined the development of foreign body giant cells in intimate contact with porous membranes of poly L-lactic acid containing 7% of plasticizer triethylcitrate implanted in the backs of rats. The membranes were removed 2, 7, 14, 21, 28, 60, 90 and 180 days after implantation, along with a portion of the tissue around the implant. Histological analysis of the implant and tissue revealed the formation of a fibrous capsule from the seventh day of implantation onwards. Foreign body giant cells appeared from the seventh day and increased in number up to the twenty-eighth day and then up to the ninetieth day of implantation, remaining constant up to the end of the study onwards, and increased in number up to the ninetieth day after implantation and then remained constant. The number of nuclei in these cells increased from the seventh day of implantation up to the ninetieth day and then up to the end of the study. © Springer Science + Business Media, LLC 2006. AD - Laboratory of Biomaterials, Center of Medical and Biological Sciences, PUC/SP, 18030-230, Sorocaba, SP, Brazil Department of Histology and Embryology, Institute of Biology, State University of Campinas (UNICAMP), PO Box 6109, 13083-970, Campinas, SP, Brazil AU - Maluf-Meiken, L. C. V. AU - Silva, D. R. M. AU - Duek, E. A. R. AU - Alberto-Rincon, M. C. DB - Scopus DO - 10.1007/s10856-006-8476-7 IS - 5 M3 - Article N1 - Cited By :10 Export Date: 10 November 2020 PY - 2006 SP - 481-485 ST - Morphometrical analysis of multinucleated giant cells in subdermal implants of poly-lactic acid in rats T2 - Journal of Materials Science: Materials in Medicine TI - Morphometrical analysis of multinucleated giant cells in subdermal implants of poly-lactic acid in rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33744786028&doi=10.1007%2fs10856-006-8476-7&partnerID=40&md5=dfa15230088ec87431c98f8b918c147d VL - 17 ID - 1584 ER - TY - JOUR AB - Complications of microsuture repair of peripheral nerves include mechanical trauma, foreign body reaction, impairment of vascularity, and possible obstruction to successful sprouting. In addition, there are occasions when it is virtually impossible to perform a suture repair because of limited exposure and/or very fine structures, such as are encountered in pediatric cases. These situations have continued to provide the impetus for evaluating alternative methods of nerve coaptation. Recently, the use of tissue glue has gained in popularity as a technique for sutureless nerve repairs. We decided to test the efficacy of fibrin glue repair versus microsuture coaptation in the rat sciatic model. The repair sites were assessed for tensile strength, by quantitative morphometry, and by electrophysiologic studies. Tensile strength findings revealed that at two, four, and eight weeks after surgery, there was no significant difference between the two repair techniques, although there was a trend toward a stronger hold in the microsuture repairs. Electrophysiologic recordings revealed that conventional microsuture repairs had significantly faster conduction velocities, larger area under the curve, and higher peak amplitudes. The onset and peak latencies were comparable, revealing that the axonal quality of at least a certain number of axons was similar electrically. Axonal counts both proximal and distal to the repair showed no significant difference, although there was an overall suggestion of superiority in the number of myelinated axons in the suture repair. AD - Microsurgical Research Center, 700 Olney Rd., P.O. Box 1980, Norfolk, VA 23501, United States AU - Maragh, H. AU - Meyer, B. S. AU - Davenport, D. AU - Gould, J. D. AU - Terzis, J. K. DB - Scopus DO - 10.1055/s-2007-1006838 IS - 4 M3 - Article N1 - Cited By :44 Export Date: 10 November 2020 PY - 1990 SP - 331-337 ST - Morphofunctional evaluation of fibrin glue versus microsuture nerve repairs T2 - Journal of Reconstructive Microsurgery TI - Morphofunctional evaluation of fibrin glue versus microsuture nerve repairs UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025252428&doi=10.1055%2fs-2007-1006838&partnerID=40&md5=6414e9b6b25f65555a4eae9d62074f56 VL - 6 ID - 1740 ER - TY - JOUR AN - 104286591. Language: English. Entry Date: 20130509. Revision Date: 20150819. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 1 KW - Charting Nursing Records -- Utilization Perioperative Nursing Academic Medical Centers Human Inpatients Italy Patient Satisfaction Questionnaires Surgery, Otorhinolaryngologic Surgical Count Procedure Surveys N1 - forms; research; tables/charts. Journal Subset: Continental Europe; Europe; Nursing; Peer Reviewed. Special Interest: Critical Care; Perioperative Care. PY - 2013 SN - 1592-5951 SP - 29-35 ST - Monitoraggio utilizzo scheda peri-operatoria infermieristica Azienda Ospedaliero-Universitaria di Parma T2 - SCENARIO: Official Italian Journal of ANIARTI TI - Monitoraggio utilizzo scheda peri-operatoria infermieristica Azienda Ospedaliero-Universitaria di Parma UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104286591&site=ehost-live&scope=site VL - 30 ID - 741 ER - TY - JOUR AB - Purpose: To explore the clinical features, visual outcomes, and prognostic factors of visual impairment of eyes that underwent vitrectomy after open globe injuries (OGIs). Methods: A retrospective review was conducted of consecutive cases that underwent pars plana vitrectomy (PPV) after OGIs at Massachusetts Eye and Ear (MEE) over 2 years. Demographic and clinical data including age, gender, type and zone of injury, presenting visual acuity (VA), vitreous hemorrhage (VH), hemorrhagic choroidals (HC), retinal detachment (RD), retinal incarceration (RI), length of follow-up, and final VA were recorded. Results: 37 eyes of 37 patients (27 male) presented with a mean age of 50.6 yo (19-88) and a mean follow-up of 438 days (89-1293). Types of injury included blunt rupture (48.7%), penetrating laceration (29.7%), and intraocular foreign body (21.6%). The injuries requiring vitrectomy were most often in zones II and III, with only 7 (27%) presenting with isolated zone I injuries. The majority of eyes had severe vision loss prior to PPV, with VA better than counting fingers in only 27%. No eyes were deemed inoperable or required subsequent enucleation. Final retinal attachment rate was 82% at last follow-up. Overall, final VA showed significant improvement with 62.2% better than counting fingers and 37.8% better than 20/50. We further stratified eyes into 2 groups based on the presence of RD at the time of initial PPV: group 1 (n=18) had no RD while group 2 (n=19) did have an RD. In group 2 with RD, there was a statistically significant improvement in average VA (logMAR 3.08 at presentation compared to 1.4 at final follow-up, p=0.00025). Those who re-detached had worse final VA (median logMAR 2.7 compared to 1.35, p=0.06), and a strong predictor of re-detachment was the appearance of PVR after the first vitrectomy (p=0.001), while the presence of PVR before the first vitrectomy did not predict ultimate re-detachment (p=1). Presence of retinal incarceration and funnel RD trended toward higher risk of re-detaching and worse final VA, but did not reach statistical significance. Conclusions: OGIs often require retina surgery after the initial open globe repair. Modern pars plana vitrectomy can lead to globe salvage and improvement in vision in even the most severe cases, suggesting that in select cases, vitrectomy after OGR may be warranted. AD - A. Marmalidou, Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, United States AU - Marmalidou, A. AU - Rossin, E. AU - Kim, L. A. AU - Wu, D. M. AU - Miller, J. B. DB - Embase IS - 9 KW - adult blindness choroid clinical article clinical outcome conference abstract controlled study ear female finger follow up gender human intraocular foreign body laceration male Massachusetts middle aged outcome assessment pars plana vitrectomy retina detachment retina surgery retrospective study rupture statistical significance visual acuity vitrectomy vitreous hemorrhage LA - English M3 - Conference Abstract N1 - L629935314 2019-11-29 PY - 2019 SN - 1552-5783 ST - Modern visual and clinical outcomes of vitrectomy after open globe injury T2 - Investigative Ophthalmology and Visual Science TI - Modern visual and clinical outcomes of vitrectomy after open globe injury UR - https://www.embase.com/search/results?subaction=viewrecord&id=L629935314&from=export VL - 60 ID - 312 ER - TY - JOUR AB - A 30-year-old patient went to the emergency department because of a chemical burn to the left eye more than 10 days ago by toilet cleanser. Surprisingly, a small piece of glass was found in the inferior anterior chamber in the same eye. The visual acuity was counting fingers. There was conjunctival congestion, corneal oedema and Descemet's membrane striae. And there was also a corneal leukoma around 4 to 5 o'clock. Through repeated questioning he recalled that he was injured by an exploded light bulb around 21 years ago. He was asymptomatic until he saw "something moving" in front of the left eye one month ago. Computed tomography (CT) scanning, ultrasonography, ultrasound biomicroscopy (UBM), anterior segment optical coherence tomography (AS-OCT) verified the presence of multiple intraocular foreign bodies (IOFBs) in the anterior chamber and vitreous cavity. B-scan verified the IOFB in the vitreous cavity. Thus, he was diagnosed with corneal chemical burn, IOFBs and corneal leukoma of the left eye. The IOFB in the anterior chamber was removed through surgery. An attempt was made to remove the IOFB in the vitreous cavity with electromagnet, but it was not successful. Vitrectomy could not be performed as it was hindered by the opacity of cornea. After surgery, the visual acuity remained counting fingers and the corneal oedema still existed. This case is a reminder that a detailed history taking, a thorough physical examination and modern imaging techniques are beneficial for establishing the diagnosis and treatment of IOFBs. AD - Department of Ophthalmology, West China Hospital of Sichuan University, 37 Guoxue Xiang, Chengdu, Sichuan, 610041, PR China; Department of Optometry and Visual Science, West China Hospital of Sichuan University, 37 Guoxue Xiang, Chengdu, Sichuan, 610041, PR China. Department of Ophthalmology, West China Hospital of Sichuan University, 37 Guoxue Xiang, Chengdu, Sichuan, 610041, PR China. Electronic address: liuchunlingsc@163.com. Department of Ophthalmology, West China Hospital of Sichuan University, 37 Guoxue Xiang, Chengdu, Sichuan, 610041, PR China; Department of Optometry and Visual Science, West China Hospital of Sichuan University, 37 Guoxue Xiang, Chengdu, Sichuan, 610041, PR China. Electronic address: longqianliu@hotmail.com. Department of Ophthalmology, West China Hospital of Sichuan University, 37 Guoxue Xiang, Chengdu, Sichuan, 610041, PR China. AN - 28844655 AU - Yang, X. AU - Liu, C. AU - Liu, L. AU - Zhang, L. DA - Dec DO - 10.1016/j.clae.2017.08.002 DP - NLM ET - 2017/08/29 IS - 6 KW - Adult Anterior Chamber/diagnostic imaging/injuries Cornea/*diagnostic imaging Diagnosis, Differential *Diagnostic Errors Eye Foreign Bodies/*diagnosis/etiology/physiopathology Eye Injuries, Penetrating Humans Male Microscopy, Acoustic Time Factors Tomography, Optical Coherence Tomography, X-Ray Computed *Visual Acuity Asymptomatic Glass Intraocular foreign body Ocular trauma LA - eng N1 - 1476-5411 Yang, Xubo Liu, Chunling Liu, Longqian Zhang, Lanlan Case Reports Journal Article England Cont Lens Anterior Eye. 2017 Dec;40(6):432-435. doi: 10.1016/j.clae.2017.08.002. Epub 2017 Aug 24. PY - 2017 SN - 1367-0484 SP - 432-435 ST - A missed diagnosis of multiple intraocular foreign bodies for 21 years T2 - Cont Lens Anterior Eye TI - A missed diagnosis of multiple intraocular foreign bodies for 21 years VL - 40 ID - 197 ER - TY - JOUR AB - BACKGROUND: An estimated 1,500 operations result in retained surgical items (RSIs) each year in the United States, resulting in substantial morbidity. The rarity of these events makes studying them difficult, but miscount incidents may provide a window into understanding risk factors for RSIs. METHODS: A cohort study of all consecutive operative cases during a 12-month period was conducted at a large academic medical center to identify risk factors for surgical miscounts. A multidisciplinary electronic miscount reconciliation checklist (necessitating both surgeon and nurse input) was introduced into the internally developed electronic Perioperative Information Management System to build a predictive model for RSI cases. RESULTS: Among 23,955 operations, 84 resulted in miscount incidents (0.35% [95% confidence interval: 0.28% to 0.43%]). Increased case duration was strongly associated with increased risk of a miscount in unadjusted analyses (p < .0001). In the nested case-control analysis, both the case duration and the number of providers present were independently associated with a more than doubling of the odds of a miscount, even after adjustment for one another, the elective/urgent/emergent status of a case, and personnel changes occurring during the case. CONCLUSIONS: The finding that both the length of the case and the number of providers involved in the case were independent risk factors for miscount incidents may offer insight into risk-targeted strategies to prevent RSIs, such as postoperative imaging, bar-coded surgical items, and radiofrequency technology. Miscounts trigger use of the Incorrect Count Safety Checklist, which can be used to determine whether a count completed at the procedure's conclusion is consistent across disciplines (circulating nurses, scrub persons, surgeons). AD - Weill Cornell Medical College, New York City, NY, USA. tij2004@med.cornell.edu AN - 24195200 AU - Judson, T. J. AU - Howell, M. D. AU - Guglielmi, C. AU - Canacari, E. AU - Sands, K. DA - Oct DO - 10.1016/s1553-7250(13)39060-6 DP - NLM ET - 2013/11/08 IS - 10 KW - Academic Medical Centers/*statistics & numerical data Age Factors Cohort Studies Foreign Bodies/*classification/*epidemiology Humans Personnel, Hospital/statistics & numerical data Quality of Health Care Risk Factors Surgical Procedures, Operative/*statistics & numerical data Time Factors United States LA - eng N1 - Judson, Timothy J Howell, Michael D Guglielmi, Charlotte Canacari, Elena Sands, Kenneth Journal Article Netherlands Jt Comm J Qual Patient Saf. 2013 Oct;39(10):468-74. doi: 10.1016/s1553-7250(13)39060-6. PY - 2013 SN - 1553-7250 (Print) 1553-7250 SP - 468-74 ST - Miscount incidents: a novel approach to exploring risk factors for unintentionally retained surgical items T2 - Jt Comm J Qual Patient Saf TI - Miscount incidents: a novel approach to exploring risk factors for unintentionally retained surgical items VL - 39 ID - 144 ER - TY - JOUR AB - Three cemented femoral components from total hip arthroplasties retrieved at autopsy were examined in regard to the migration of birefringent polyethylene particles across the fixation interfaces. They were obtained from two patients who died from unrelated causes. They had been in place, respectively, for 8 and 9 years (first patient) and for 9 years (second patient). Osteolysis was present in the acetabular side only. The femoral components were not loosened. Histologic sections were performed at four levels of the femoral components, and polyethylene particles were counted with the use of a semiautomatic image analyzer. Sections below the tip of the stem were treated by deorganification and the lysate was centrifuged in the attempt to isolate wear debris. Particles were found at both interfaces (bone-cement and metal-cement) and in the cancellous bone between the trabeculae. They were also present in the Haversian canals of the cortical bone. Particles of various sizes were found in the medullary canal beneath the tip of the stem. In scanning electron microscopy, they appeared to have irregular shapes. Wear debris can migrate across the cement-bone interface of nonloosened implants. They appear to progress through the porosity of the cancellous bone. © 2004 Wiley Periodicals, Inc. AD - P. Massin, Department of Orthopaedic Surgery, Angers University Hospital, 4 rue Larrey, 49033 Angers Cedex 01, France AU - Massin, P. AU - Chappard, D. AU - Flautre, B. AU - Hardouin, P. DB - Embase Medline DO - 10.1002/jbm.b.30001 IS - 2 KW - polyethylene aged article autopsy case report female femur femoral neck fracture foreign body hip arthroplasty hip prosthesis histology human implant osteolysis scanning electron microscopy total hip prosthesis LA - English M3 - Article N1 - L38619778 2004-06-02 PY - 2004 SN - 0021-9304 SP - 205-215 ST - Migration of Polyethylene Particles Around Nonloosened Cemented Femoral Components from a Total Hip Arthroplasty - An Autopsy Study T2 - Journal of Biomedical Materials Research - Part B Applied Biomaterials TI - Migration of Polyethylene Particles Around Nonloosened Cemented Femoral Components from a Total Hip Arthroplasty - An Autopsy Study UR - https://www.embase.com/search/results?subaction=viewrecord&id=L38619778&from=export http://dx.doi.org/10.1002/jbm.b.30001 VL - 69 ID - 635 ER - TY - JOUR AB - To determine the effects of local bone turnover on the migration of macroporous hydroxyapatite onlays in the nasal bone and mandibular ramus, we performed histomorphometric analyses of the underlying bone area in 41 New Zealand White rabbits from the age of 4 weeks. The hydroxyapatite implants were placed under the periosteum of the right nasal bone (a depository bone onto its periosteal surface and endosteal resorptive) and the mandibular ramus (resorptive onto its outer surface). The corresponding left sides were sham operated. Following fluorescence bone labeling, composite specimens of the hydroxyapatite block including both sides of the nasal bone and mandible were removed at 0 (m = 1), 3, 6, 9, 12, and 16 weeks postoperatively (n = 8, respectively) and processed to yield undecalcified sections. Bone-bone marrow interfaces in the entire area within 200 μm beneath the base of the hydroxyapatite and in the counter-area on the sham-operated side were measured under a light microscope. In all grafted specimens, the hydroxyapatite matrix was directly united with the underlying tissue by bone ingrowth. However, the sinking of the hydroxyapatite graft in the nasal bone was significant at 3 weeks postoperatively and gradually increased thereafter. In the mandible, the sinking became significant at 6 weeks. In the nasal bone, the bone are density beneath the graft showed a time- dependent decrease during the experimental period, but in the mandibular bone, the value was initially decreased at 3 weeks and then recovered to baseline level. In both bones, parameters of bone resorption, such as osteoclast number and osteoclast surface, were significantly increased from 3 weeks. While the parameters of bone formation, such as osteoblast surface and mineralizing surface, were significantly decreased from 3 weeks in the nasal bone, they were significantly increased in the mandible. Mineral apposition rate showed a significant decrease in both bones. Our data indicate that while the bone area density beneath the hydroxyapatite seemed to depend on bone formation, increased bone resorption would be more critical for the remodeling of underlying bony architecture in the migration of the hydroxyapatite graft. AD - Dept. of Plast. and Reconstr. Surg., Nagasaki Univ. School of Medicine, 1-7-1 Sakamoto-machi, Nagasaki 852, Japan AU - Yanagisawa, A. AU - Nakamura, T. AU - Arakaki, M. AU - Yano, H. AU - Yamashita, S. AU - Fujii, T. DB - Scopus DO - 10.1097/00006534-199706000-00024 IS - 7 M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 1997 SP - 1972-1982 ST - Migration of hydroxyapatite onlays into the mandible and nasal bone and local bone turnover in growing rabbits T2 - Plastic and Reconstructive Surgery TI - Migration of hydroxyapatite onlays into the mandible and nasal bone and local bone turnover in growing rabbits UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030907552&doi=10.1097%2f00006534-199706000-00024&partnerID=40&md5=fc03bd026a8610a734c763c1fb0958c0 VL - 99 ID - 1705 ER - TY - JOUR AB - Foreign body ingestion is not an uncommon problem encountered in clinical practice. However, the associated complication of bowel perforation and migration of the foreign body to the liver is rare. We report two cases of hepatic foreign bodies identified intra-operatively as toothpicks, with the alimentary tract being the presumed origin. © 2009 The British Institute of Radiology. AD - Department of Radiology, Guangdong Provincial People's Hospital, Guangzhou, Guangdong Province 510080, China AU - Liu, H. J. AU - Liang, C. H. AU - Huang, B. AU - Xie, S. F. AU - Wang, G. Y. DB - Scopus DO - 10.1259/bjr/16399296 IS - 976 M3 - Article N1 - Cited By :11 Export Date: 10 November 2020 PY - 2009 SP - e79-e81 ST - Migration of a swallowed toothpick into the liver: The value of multiplanar CT T2 - British Journal of Radiology TI - Migration of a swallowed toothpick into the liver: The value of multiplanar CT UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-65349098054&doi=10.1259%2fbjr%2f16399296&partnerID=40&md5=4963c0991e8e21eecb402a523cc21566 VL - 82 ID - 1495 ER - TY - JOUR AB - We describe a patient in whom a fish bone penetrated the duodenum and migrated into the right renal vein. The bone was successfully removed with surgery. The 75-year-old man was admitted to Nippon Medical School Tama Nagayama Hospital because of right upper abdominal pain persisting for 7 days. The patient's medical history was not relevant to the current disorder. Plain radiography showed no abnormalities. Computed tomography revealed a linear object of high intensity that had penetrated the duodenum and migrated into the right renal vein with thrombus. The object was surrounded by a low-density area, suggesting severe inflammation. The patient had eaten fish 1 day before the onset of abdominal pain. We diagnosed duodenal penetration caused by an ingested fish bone. Endoscopic examination showed erosion, but no fish bone or ulceration was detected in the duodenum. The patient was treated conservatively with fasting, peripheral parental nutrition, and intravenous antibiotics. Three days after admission, non-contrast-enhanced computed tomography showed no movement of the foreign body. The patient continued to have pain, and the decision was made to surgically explore the abdomen. Intraoperative ultrasonography showed that the foreign body had migrated completely into the right renal vein with thrombus. Severe inflammation of the right renal vein was observed. Because we could not remove the foreign body without seriously injuring the right renal vein, right nephrectomy was performed. Macroscopic examination of the surgical specimen confirmed the presence of a fish bone with thrombus in the right renal vein. The patient was discharged 9 days after operation, with no complications. AD - Surgery for Organ Function and Biological Regulation, Graduate School of Medicine, Nippon Medical School, Japan Department of Surgery, Nippon Medical School Tama Nagayama Hospital, Japan AU - Iwai, T. AU - Yoshida, H. AU - Yokoyama, T. AU - Maruyama, H. AU - Suzuki, S. AU - Matsutani, T. AU - Matsushita, A. AU - Hirakata, A. AU - Sasajima, K. AU - Uchida, E. DB - Scopus DO - 10.1272/jnms.78.189 IS - 3 KW - Fish bone Migration Renal vein M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2011 SP - 189-193 ST - Migration of a fish bone into the right renal vein T2 - Journal of Nippon Medical School TI - Migration of a fish bone into the right renal vein UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79959767470&doi=10.1272%2fjnms.78.189&partnerID=40&md5=d24f4b13873e3b9c1f70106a0b438d29 VL - 78 ID - 1413 ER - TY - JOUR AB - A 15-year-old girl was referred to our Pediatric Emergency Unit because of recurrent fever associated with a painful right laterocervical mass over the previous four months, which was unresponsive to various antimicrobial therapies. During surgery, performed to obtain a biopsy, an unexpected vegetable thin fibre, about 1.2 cm long, was found among the laterocervical lymph nodes. The patient subsequently experienced complete clinical remission and told us that about one month before the development of symptoms she had felt a punctory sensation in the floor of her mouth after she had been playing with a blade of grass between her lips. © 2009. AD - Foundation IRCCS University of Milan, Department of Specialistic Surgical Sciences, ENT Unit - Ospedale Policlinico, Mangiagalli, Regina Elena, Via F. Sforza 35, 20122 Milan, Italy Institute of Pediatrics, Ospedale Policlinico, Mangiagalli, Regina Elena, Foundation IRCCS, University of Milan, Milan, Italy AU - Pignataro, L. AU - Laguardia, M. AU - Esposito, S. AU - Bosis, S. AU - Torretta, S. AU - Principi, N. AU - Capaccio, P. DB - Scopus DO - 10.1016/j.pedex.2008.12.003 IS - 4 KW - Cervical lymphadenopathy Foreign body Migration M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2009 SP - 169-172 ST - Migrating foreign body of the neck as a cause of recurrent febrile lymphadenopathy T2 - International Journal of Pediatric Otorhinolaryngology Extra TI - Migrating foreign body of the neck as a cause of recurrent febrile lymphadenopathy UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-69449092776&doi=10.1016%2fj.pedex.2008.12.003&partnerID=40&md5=f656f19d697da6e94705a992b45f20f7 VL - 4 ID - 1481 ER - TY - JOUR AB - Deep neck infections are not uncommon; however, a migrating fish bone is seldom a cause of a deep neck abscess. Fish bones are a sharp foreign body and can penetrate the oropharynx or esophagus. However, this rarely occurs. We report a case of deep neck abscess resulting from the intracorporeal migration of a fish bone. Initial radiography and esophagoscopy of the neck were both negative; migration of the bone was ultimately documented by computed tomography. Surgical exploration was performed via a lateral neck incision, and the fish bone was successfully retrieved. Although fish bones are a rare etiology of deep neck abscesses, should be kept in mind when a patient has the history of fish bone ingestion. AD - Department of Otolaryngology Head and Neck Surgery, Chang Gung Memorial Hospital, Keelung, Taiwan Department of Otolaryngology Head and Neck Surgery, Chang Gung Memorial Hospital, 222, Maijin Rd, Anle Chiu, Keelung 204, Taiwan AU - Yang, S. W. AU - Chen, T. M. AU - Chen, T. A. DB - Scopus IS - 12 KW - Abscess Deep neck infection Fish bone Migratory M3 - Article N1 - Cited By :13 Export Date: 10 November 2020 PY - 2005 SP - 872-875 ST - Migrating fish bone complicating a deep neck abscess T2 - Chang Gung Medical Journal TI - Migrating fish bone complicating a deep neck abscess UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33344463648&partnerID=40&md5=f7bf3fb0a4bca42a8f1aceb6e9dc6880 VL - 28 ID - 1595 ER - TY - JOUR AB - Objectives: The purpose was to evaluate inflammatory and microcirculatory reactions after implantation of various calcium phosphate bone substitutes in an in vivo model. Methods: Calcium phosphate-based bone substitutes were implanted in dorsal skinfold chambers of mice. Intravital fluorescence microscopy was performed to measure inflammatory and microcirculatory reactions based on functional vessel density (FVD), capillary leakage, and relative white blood cell velocity (rWBCV). Results: An increase of FVD was observed in all groups and the capillary leakage grew with a level of significance (p<0.001). The fraction of rolling and sticking leukocytes (rWBCV) was highest at the beginning of the trial and decreased during the course. Conclusions: There are differences in microvascular soft tissue reactions between various calcium phosphate bone substitutes, but inflammatory reactions were moderate, and the results revealed no reasons which explain the sporadic failure of the tested substances under clinical conditions. © Springer-Verlag 2010. AD - Chirurgische Klinik und Poliklinik, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH, Bürkle-de-la-Camp Platz 1, 44795 Bochum, Germany Klinik für Plastische-, Hand- und Schwerstverbranntenchirurgie, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH, Bürkle-de-la-Camp Platz 1, 44795 Bochum, Germany Universitätsklinik für Unfallchirurgie und Sporttraumatologie, Medizinische Universitätsklinik, Graz, Auenbrugger Platz 7a, 8036 Graz, Austria Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH, Chirurgische Klinik und Poliklinik, Bürkle-de-la-Camp Platz 1, 44789 Bochum, Germany AU - Roetman, B. AU - Ring, A. AU - Langer, S. AU - Schildhauer, T. A. AU - Muhr, G. AU - Köller, M. DB - Scopus DO - 10.1007/s00423-010-0608-3 IS - 8 KW - Dorsal skinfold chamber Fluorescence microscopy Inflammatory reaction Microvascular response Resorbable bone substitutes M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2010 SP - 1147-1155 ST - Microvascular response to calcium phosphate bone substitutes: An intravital microscopy analysis T2 - Langenbeck's Archives of Surgery TI - Microvascular response to calcium phosphate bone substitutes: An intravital microscopy analysis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79952827101&doi=10.1007%2fs00423-010-0608-3&partnerID=40&md5=0512d5b04876aa8a0b4e22825c7a15e0 VL - 395 ID - 1478 ER - TY - JOUR AB - objective: To describe the use of micafungin and fluconazole in the management of a fungal prosthetic joint infection caused by Candida albicans. case summary: A 55-year-old female who had undergone total left knee arthroplasty due to rheumatoid arthritis presented with symptoms of a left knee infection. Intravenous vancomycin 1 g every 12 hours and intravenous ampicillin/ sulbactam 1.5 g every 6 hours were initiated. Arthrocentesis produced cloudy synovial fluid with a white blood cell (WBC) count of 5.995 × 10 3/μL C-reactive protein (CRP) was 19.8 mg/dL and erythrocyte sediment rate (ESR) was greater than 120 mm/h. Gram stain was negative, but intraoperative cultures grew C. albicans. Four days later the patient's condition worsened and repeat arthrocentesis showed WBC count of 16.8 × 103/μL with budding yeast in the synovial fluid. Antibiotics were stopped and liposomal amphotericin B 5 mg/kg once daily was started but was stopped after a few doses due to renal failure. Intravenous micafungin 100 mg daily was initiated: intravenous fluconazole 400 mg daily was added 2 days later and subsequently changed to oral fluconazole after 2 days of therapy. The patient received combination micafungin/fluconazole therapy for 8 weeks. After approximately 8 weeks of therapy, the CRP level and ESR had decreased from 19.8 to 7.1 mg/dL and greater than 120 to 81 mm/h. respectively. The patient's pain and range of motion in her knee had returned to baseline levels at last follow-up after the total knee arthroplasty. After 8 weeks of combination therapy, micafungin was discontinued but oral fluconazole was continued; approximately 8 weeks later the patient relapsed, requiring removal of the prosthetic knee hardware. discussion: Fungal prosthetic joint infections are rare, but definitive data regarding appropriate treatment are lacking. Echinocandins are an attractive treatment option due to their enhanced biofilm penetration. In our patient, treatment with micafungin plus fluconazole for 8 weeks followed by fluconazole monotherapy was associated with an initial good outcome in the treatment of a C. albicans prosthetic knee infection with retained hardware. This was, to our knowledge, the first case using micafungin in a prosthetic joint infection. conclusions: Although micafungin plus fluconazole showed positive results in our patient, more data are needed regarding combination therapy for fungal prosthetic joint infections. AD - C. M. Bland, Dwight D Eisenhower Army Medical Center, Building 300, Hospital Road, Fort Gordon, GA 30905 AU - Bland, C. M. AU - Thomas, S. DB - Embase Medline DO - 10.1345/aph.1L508 IS - 3 KW - amphotericin B lipid complex antibiotic agent C reactive protein fluconazole micafungin polyethylene sultamicillin vancomycin adult arthrocentesis article bacterium culture Candida albicans candidiasis case report clinical feature computer disease exacerbation drug withdrawal erythrocyte sedimentation rate female human intraoperative period joint prosthesis knee pain leukocyte count monotherapy priority journal range of motion retained instrument rheumatoid arthritis synovial fluid total knee arthroplasty treatment duration treatment outcome LA - English M3 - Article N1 - L354365323 2009-04-06 PY - 2009 SN - 1060-0280 SP - 528-531 ST - Micafungin plus fluconazole in an infected knee with retained hardware due to candida albicans T2 - Annals of Pharmacotherapy TI - Micafungin plus fluconazole in an infected knee with retained hardware due to candida albicans UR - https://www.embase.com/search/results?subaction=viewrecord&id=L354365323&from=export http://dx.doi.org/10.1345/aph.1L508 VL - 43 ID - 585 ER - TY - JOUR AB - In 2 cases of Japanese schistosomiasis associated with colon carcinoma and with a giant polyp suggesting partially malignant changes of the sigmoid colon, respectively, microscopic counting of the total number of eggs distributed throughout the whole operation materials was tried. Thickness of boundary mucosae between cancer lesions and intact parts was measured. Then, constitutions responsible for their mucosal thickness were histologically investigated. As base on these metrical data, the present study was designed to elucidate collaborative findings of carcinogenesis with eggs. The data obtained herein lead to the following conclusions: 1) Complete absence of eggs in tumor lesions and their adjacent areas proximal to anus. 2) Numbers of eggs in submucosal layers of whole area approximately equal to those in the entire wall of rectum. 3) No definite foreign-body reaction on eggs. 4) No intimate relationship between the egg localisation and proliferation of mucosal elements. 5) Various values of thickness and abundant histological aspects in boundary mucosal areas between cancer and intact parts. 6) The mucosal thickness of 6 mm. consistently indicated that of carcinoma, themselves. 7) Values, meas. up to 2 or 4 mm, were expressed as the summation of the thickness of intra- and/or submucosal cancer nests, and intact mucosa, with occasional distinct lateral extension. 8) No transitional pictures between carcinoma and intact mucosal constituents in histology. 9) Scanty numbers of eggs in the boundary areas. 10) Non-specific glandular hyperplasia quite regardless of malignant transformation. © 1976, The Japanese Society of Gastroenterology. All rights reserved. AD - 1st Department of Pathology, School of Medicine, Teikyo University, Japan Center of Anal Surgery, Risshoh-Kohseikai Hosiptal, Tokyo, Japan AU - Tokoro, Y. AU - Koganezawa, S. DB - Scopus DO - 10.11405/nisshoshi1964.73.972 IS - 8 M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 1976 SP - 972-985 ST - Metrical and Histopathological Studies on 2 Cases of Japanese Schistosomiasis Displaying Tremendous Numbers of Eggs Combined with Colon Cancers T2 - Nippon Shokakibyo Gakkai Zasshi TI - Metrical and Histopathological Studies on 2 Cases of Japanese Schistosomiasis Displaying Tremendous Numbers of Eggs Combined with Colon Cancers UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0017177532&doi=10.11405%2fnisshoshi1964.73.972&partnerID=40&md5=d53698632516e85caaa410e90e83c476 VL - 73 ID - 1772 ER - TY - JOUR AB - Methylene blue (aniline violet, tetra-methylthionine chloride) has several important uses in clinical medicine, including diagnosis of displaced central lines. After cardiac surgery, three infants with suspected displacement of direct atrial lines were given methylene blue. After injection of the dye into the atrial lines, bluish discolouration was identified in their chest drainage. Use of methylene blue in small amounts appears to be a safe and effective way of diagnosing extravasation of fluid from displaced central lines. AD - Paediatric Intensive Care Unit, Royal Children's Hospital, Flemington Road, Melbourne, Vic. 3052, Australia AU - Namachivayam, P. AU - Tibballs, J. DB - Scopus DO - 10.1177/0310057x0603400213 IS - 2 KW - Atrial line Chest drain Hypoplastic left heart syndrome Methylene blue M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2006 SP - 280-281 ST - Methylene blue for diagnosis of displaced atrial lines T2 - Anaesthesia and Intensive Care TI - Methylene blue for diagnosis of displaced atrial lines UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33645791478&doi=10.1177%2f0310057x0603400213&partnerID=40&md5=61a1e339d87b4832709b96a2518b1827 VL - 34 ID - 1590 ER - TY - JOUR AB - Background: Metastatic Crohn's disease (CD) involves the presence of cutaneous granuloma distant from the intestinal lesions related to the disease, usually observed in colonic CD. Case history: A 35-year-old female with a permanent ileostomy following proctocolectomy for CD presented in 1999 with a 2-month history of an unusual skin lesion of the forehead. A diagnosis of CD of the ileum, colon, and rectum had been made in 1994. In 1997, a proctocolectomy with ileostomy was performed due to fistulizing severe refractory disease. Microscopic aspects of the intestinal lesions showed deep and fissuring ulcers. After surgery, she went into remission, and a small bowel follow-up in 1999 showed no recurrence, when she presented with the skin lesion of the forehead. Microscopic data: Histological analysis of endoscopical and surgical intestinal specimens showed chronic granulomatous inflammation of the ileum, colon, and rectum, confirming the diagnosis of CD. The forehead skin biopsy was examined by three independent histopathologists. The lesion was composed of numerous small granulomas (Ziehl-Nielsen negative), with no foreign bodies, mainly composed of CD68-positive and periodic acid Schiff-negative monocytes. Despite the low number of lymphocytes, the macroscopical and microscopical aspect of the forehead lesion, together with the clinical history, led to a diagnosis of rare metastatic CD of the forehead. Conclusions: This case report describes the development of an unusual granulomatous skin lesion of the forehead in a patient with established CD showing no postoperative recurrence. AD - Department of Internal Medicine, Unit of Gastroenterology, University of Rome Tor Vergata, Rome, Italy Department of Internal Medicine, Unit of Dermatology, University of Rome Tor Vergata, Rome, Italy Department of Pathology, University of Rome Tor Vergata, Rome, Italy Department of Pathology, University Hospital Gasthuisberg, Leuven, Belgium Centro di Eccellenta per il Rischio Genomio di Patologie Multifattoriali, Fondazione Pro Mater, Italy Cattedra di Gastroenterologia, Dipartimento di Medicina Interna, Università degli Studi di Roma Tor Vergata, Via di Tor Vergata 135, 00133 Rome, Italy AU - Biancone, L. AU - Geboes, K. AU - Spagnoli, L. G. AU - Del Vecchio Blanco, G. AU - Monteleone, I. AU - Vavassori, P. AU - Palmieri, G. AU - Chimenti, S. AU - Pallone, F. DB - Scopus DO - 10.1097/00054725-200203000-00006 IS - 2 KW - Crohn's disease Granulomatous disease Metastatic Crohn's disease Skin lesion, forehead M3 - Article N1 - Cited By :19 Export Date: 10 November 2020 PY - 2002 SP - 101-105 ST - Metastatic Crohn's disease of the forehead T2 - Inflammatory Bowel Diseases TI - Metastatic Crohn's disease of the forehead UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036198720&doi=10.1097%2f00054725-200203000-00006&partnerID=40&md5=ae79de1b949b8defb09f582614f95e7a VL - 8 ID - 1664 ER - TY - JOUR AB - Objective: Of the 350,000 annual Urogynecologic surgeries utilizing mesh, 5% result in mesh removal for complications-most commonly mesh exposure and pain. Regulatory T cells (Tregs), a subset of T helper (Th) cells, promote tolerance to foreign bodies by modifying macrophage differentiation. A profibrotic response characterized by increased type-2 macrophages has been reported in mesh removed for pain but the role of Tregs in mesh complications has not been explored. We sought to determine if decreased Tregs are associated with an increased fibrotic response and if fewer Tregs will be seen in mesh removed for pain as compared to exposure. Methods: Mesh-tissue complexes were removed for pain (N=8) or exposure (N=8). Immunofluorescent labeling of CD4 (Th), and foxp3 (Tregs) was performed (Figure 1A) then stained with Trichrome (Figure 1B). Samples were divided into 0.25 μm2 grids for cell counts. Grids were classified as mild, moderate or high fibrosis by a semi-quantitative assessment of collagen deposition via intensity profiling. High fibrosis was considered pathologic and was compared to mild/moderate fibrosis. Treg concentrations were compared using a mixed effects linear models for high vs mild/moderate fibrosis, Mann-U Whitney tests for pain/exposure groups, and linear regression for duration of implantation. Data is reported as mean±SD for baseline patient data and mean±SE for cell concentrations. Results: Average age was 56.7± 10.0 y, BMI28.9±1.0kg/m2 and median parity 3 (range 1-5). Of pain samples, 4 were midurethral slings (MUS) and 4 were prolapse meshes. Of exposure samples, 3 were MUS and 5 were prolapse meshes. There were no differences in age, BMI, parity, smoking, rate of diabetes, menopausal status, hormone use, or prior hysterectomy based on removal indication or mesh type (p>0.05). Mean time of implantation was 38.1±24.3 months. Tregs were decreased in areas of high fibrosis with 11.3±2.1 Treg/jjm compared to 13.1±1.5 Treg/jjm for mild/moderate areas p<0.001. Th were similarly decreased with 11.5±2.1 Th/(jm vs 13.3±2.1 Th/(jm, p<0.001. On mixed effects linear regression, there were 0.96 fewer Treg/(jm and 1.1 fewer Th/(jm in areas of high fibrosis vs mild/moderate fibrosis (p<0.001). There was no difference in Tregs between pain vs. exposure. Conclusions: Th cells, consisting primarily of Tregs, were present years after mesh implantation challenging the common notion that the adaptive immune response to a foreign body is transient. The inverse relationship between fibrosis and Tregs points to a protective role of these cells. Similar Tregs in patients with pain and exposure suggests these complications exist along the same spectrum. Further research into a potential therapeutic role of Tregs is warranted. [Figure Presented]. AD - A.M. Artsen, Magee-Womens Hospital, University of Pittsburgh, Pittsburgh, PA, United States AU - Artsen, A. M. AU - Rytel, M. AU - Liang, R. AU - Moalli, P. A. DB - Embase DO - 10.1097/SPV.0000000000000617 IS - 5 KW - CD4 antigen collagen endogenous compound hormone transcription factor FOXP3 adaptive immunity adult body mass cell count clinical article complication conference abstract controlled study diabetes mellitus disease course female fibrosis foreign body human human cell human tissue immunofluorescence implantation linear regression analysis male middle aged mixed cell culture pain parity patient coding patient history of hysterectomy prolapse protein fingerprinting quantitative analysis regulatory T lymphocyte smoking suburethral sling Th1 cell LA - English M3 - Conference Abstract N1 - L627772552 2019-05-28 PY - 2018 SN - 2154-4212 SP - S19 ST - Mesh induced fibrosis: The role of T regulatory cells T2 - Female Pelvic Medicine and Reconstructive Surgery TI - Mesh induced fibrosis: The role of T regulatory cells UR - https://www.embase.com/search/results?subaction=viewrecord&id=L627772552&from=export http://dx.doi.org/10.1097/SPV.0000000000000617 VL - 24 ID - 337 ER - TY - JOUR AB - Abdominal pain is one of the most common complaints in the pediatric ED. Because of the broad range of potential diagnoses, it can pose challenges in diagnosis and therapy in the preadolescent girl. An 11-year-old previously healthy girl presented to our pediatric ED with fever, decreased appetite, vaginal bleeding, and abdominal pain. Initial evaluation yielded elevated creatinine levels, leukocytosis with bandemia, elevated inflammatory markers, and urine concerning for a urinary tract infection. She began receiving antibiotics for presumed pyelonephritis and was admitted to the hospital. After worsening respiratory status and continued abdominal pain, a computed tomography scan was obtained and a pelvic foreign body and abscess were identified. Adolescent gynecology was consulted for examination under anesthesia for abscess drainage and foreign body removal. A foreign body in the vagina or uterus can present as vaginal discharge, vaginal bleeding, abdominal pain, dysuria, or hematuria. Because symptoms can be diverse, an intravaginal or uterine foreign body should be considered in the preteen female patient presenting to the ED with abdominal pain. © 2015 American College of Emergency Physicians. AD - Division of Emergency Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States Division of Gynecology, Department of Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States Division of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States AU - Riney, L. C. AU - Reed, J. L. AU - Kruger, L. L. AU - Brody, A. J. AU - Pomerantz, W. J. DB - Scopus DO - 10.1016/j.annemergmed.2015.06.007 IS - 5 M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2015 SP - 479-482 ST - Menarche? a case of abdominal pain and vaginal bleeding in a preadolescent girl T2 - Annals of Emergency Medicine TI - Menarche? a case of abdominal pain and vaginal bleeding in a preadolescent girl UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84945493388&doi=10.1016%2fj.annemergmed.2015.06.007&partnerID=40&md5=6865ab7e3355adec5a0e3c61321cbae7 VL - 66 ID - 1216 ER - TY - JOUR AB - The volume of malpractice litigation is steadily increasing. It is becoming more common for the plaintiff's attorney to include, along with the physician, the hospital and the nurses as defendants in appropriate situations. This is certainly true in any operating room situation. From a defense, or medicolegal point of view, it is essential that all operating room personnel take every reasonable precaution to avoid or minimize the possibility of a lawsuit. It has long been not only accepted practice but also a requirement that sponges, lap sheets and similar items be counted and accounted for before an incision is closed. The leaving of a foreign object, such as a sponge, a hemostat, or a needle in a patient is virtually conclusive proof of negligence of malpractice. Almost without exception, the courts will apply the doctrine of res ipsa loquitur, 'the thing speaks for itself', in such a situation. The general rule must be that the smaller the item, the greater the necessity for counting; all sharps, such as needles, scalpel blades and similar items. These are all items which can be as easily, if not more easily, lost in a patient than a sponge or a laparotomy sheet. AU - Russell, J. B. DB - Scopus IS - 6 M3 - Article N1 - Export Date: 10 November 2020 PY - 1974 SP - 919 ST - Medicolegal necessity for counting sharps T2 - Surgery Gynecology and Obstetrics TI - Medicolegal necessity for counting sharps UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0016318491&partnerID=40&md5=65ab128c746336f663f0389d5aac8924 VL - 139 ID - 1776 ER - TY - JOUR AB - The mechanism of action of intrauterine devices varies from one type of device to another, although the principle of action is the same, namely, to interfere with the physiology of reproduction at the endometrial level. The biochemical changes of the endometrial tissue and the composition of the uterine fluid have been reviewed in relation to the use of inert, copper-medicated and steroid-releasing IUDs. All IUDs, whether inert or medicated, provoke a significant increase in the number of neutrophils, mononuclear cells and plasma cells, the presence of which is unrelated to the tissue infiltration of inflammatory cells occurring pre-menstrually of the normal menstrual cycle. The increase of leucocytes in IUD-users is compatible with a foreign body reaction which may be related to the antifertility effect. The addition of copper to an inert IUD has been shown to significantly alter the metabolism of the endometrial cells, e.g. the enzymatic activity and the DOVA-synthesis. The steroid-medicated IUDs represent a new approach to intrauterine contraception where the morphology of the endometrium is considerably altered, showing massive decidual changes, atrophic glands and sometimes atrophy of the whole functional layer. In addition, there is an important foreign body reaction, similar to that of the inert IUDs. The enzymatic activity, as well as the proliferative activity was significantly altered in the endometrium of these IUD-users. Changes in the endometrial fibrinolytic activity in IUD-users have been demonstrated to be related to the presence of irregular bleeding. Micro-traumata of the endometrium and the increased fibrinolytic activity may also interfere with the protective processes present in the physiologically normal endometrium. Further studies on the factors influencing the fertilizing ability of the spermatozoa in the female genital tract, as well as on the conditions of the human endometrium required for the implantation of a blastocyst, may yield important information for the improvement of intrauterine contraception. © 1987. AD - Laboratory of Analytical and Quantitative Cytology 18, Boulevard des Philosophes, 1205 Geneva, Switzerland AU - Johannisson, E. DB - Scopus DO - 10.1016/0010-7824(87)90058-8 IS - 1 M3 - Article N1 - Cited By :32 Export Date: 10 November 2020 PY - 1987 SP - 11-22 ST - Mechanism of action of intrauterine devices: Biochemical changes T2 - Contraception TI - Mechanism of action of intrauterine devices: Biochemical changes UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023241861&doi=10.1016%2f0010-7824%2887%2990058-8&partnerID=40&md5=8c46ef91754ddd06cfd0811aa18e4f46 VL - 36 ID - 1746 ER - TY - JOUR AB - Objectives: The Apollo Quality Program(AQP), is a a unique platform established by Apollo Hospitals, the largest healthcare provider in India, to promulgate patient safety and quality improvement across all of its 64 Hospitals in the country, and create a robust framework for clinical governance through patient safety data measurement systems. Methods: A comprehensive set of safety-solutions, AQP, was developed, for the Group-wide implementation of standardized methodologies for clinical-handovers, international patient safety goals(IPSGs), surgical-care-improvement, medication-safety andstandardization of medical-records.Clinical-handovers were standardized. The six IPSGs as given by the JCI; patient-identifiers, read-back for verbal orders, safety of high-alert medications, sitemarking, time-outs and falls risk-assessment were introduced for all hospitals. Surgical-Care-Improvement-Plan envisages safety during surgeries by preventing wrong-site, wrong-patient, wrong-procedure surgery,surgical-site infections and foreign-body retention during surgery. Medication-Safety included standardizing the medication management plan, ensuring prescription audits of all prescriptions including discharge-summaries and measurement of medicationerrors. Minimum content of all medical-records across Group Hospitals was defined. All parameters together formed a measurable dashboard of 20 parameters with results colour coded as green, orange and red for defined ranges of scores. This dashboard was made online for monthly monitoring wherein each hospital reported compliance data.Intensive training was conducted for all units through video-conferencing.The scores of the AQP were linked to the hospitals' performance scorecard and also to the appraisal of the Medical Heads and the CEOs and helped establish clinical governance. Initiatives were undertaken at each of the unit hospitals to promote the culture of safety. Audits were conducted to validate processes and data. Results: There is a marked increase in the compliance to processes and patient-safety outcomes. The average AQP scores for all Apollo Hospitals improved from 62 in April'11 to 91 in December'17 shows an overall improvement. Various other parameters that show improvement and hence substantiate progress are: Group average percentage compliance to use of nursing-handover form for patient-handover increased from 90.40% to 99%. Compliance to use of two patient-identifiers rose from 95.42% in April'11 to 98.84% in December'17, read-back for verbal-orders from 86.69% to 97.56%, to policy for high alert medications from 87.83% to 97.78%, use of measures to prevent wrong-site, wrongpatient, wrong-procedure surgery from 85.75% to 99.17%, to handwashing from 69.18% to 91.76%, to antimicrobial prophylaxis within one hour before incision from 79.43% to 95.08%. Percentage of patients excluded from SSI calculation due to lack of follow-up for the requisite time frame decreased from 21.25% to 8.67%, compliance to communicating sponge count conveyed to surgeon before skin closure from 82.83% to 100%. Conclusion: AQP is a platform that has empowered the leadership, by providing them with a powerful data driven and evidence based mechanism to look back and introspect each of their units' performance in terms of patient safety and quality more objectively. They are enabled to undertake constructive and tangible measures to improve and drive clinical quality and patient safety processes thereby building in resilience and reliability. AD - D.A. Sibal, Group Medical Department, New Delhi, India AU - Sibal, D. A. AU - Sachdeva, P. DB - Embase DO - 10.1093/intqhc/mzy167.11 KW - antiinfective agent adult calculation clinical article clinical handover conference abstract controlled study drug safety female follow up foreign body hand washing head human incision leadership male medical record medication therapy management monitoring outcome assessment patient safety prescription prophylaxis reliability risk assessment skin surgeon surgery surgical infection videoconferencing LA - English M3 - Conference Abstract N1 - L628695413 2019-08-01 PY - 2018 SN - 1464-3677 SP - 10-11 ST - Measured for safety-the apollo quality program T2 - International Journal for Quality in Health Care TI - Measured for safety-the apollo quality program UR - https://www.embase.com/search/results?subaction=viewrecord&id=L628695413&from=export http://dx.doi.org/10.1093/intqhc/mzy167.11 VL - 30 ID - 338 ER - TY - JOUR AB - Teratomas or Germ cell tumours (GCTs) are interesting because of their obscure origin, bizarre microscopic appearance and unpredictable behaviour. Mediastinal teratoma is a slowly growing and rare tumour found in children that is diagnosed incidentally in asymptomatic patients. Most of the symptoms are related to mass compression effects such as chest pain, cough, respiratory distress and dysphagia. We report a 5-year-old male child who presented with a history of foreign body ingestion, sternal and left upper quadrant pain and vomiting without respiratory distress. The patient was incidentally found to have an anterior mediastinal mass compressing the right atrium and was diagnosed by histopathological examination as having a mature cystic teratoma of the mediastinum. The patient was successfully treated by the surgical resection of the tumour. © 2017 The Authors AD - Pediatric Department, College of Medicine, Taibah University, Almadinah Almunawwarah, Saudi Arabia Pediatric Department, Medina Maternity & Children's Hospital, Almadinah Almunawwarah, Saudi Arabia AU - AlHarbi, K. M. AU - Sairafi, M. H. AU - Almuzaini, S. A. DB - Scopus DO - 10.1016/j.jtumed.2017.06.007 IS - 6 KW - Anterior mediastinum Children Histopathology Surgical treatment Teratoma M3 - Article N1 - Export Date: 10 November 2020 PY - 2017 SP - 555-560 ST - Mature cystic teratoma of mediastinum compressing the right atrium in a child: A rare case report T2 - Journal of Taibah University Medical Sciences TI - Mature cystic teratoma of mediastinum compressing the right atrium in a child: A rare case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028657579&doi=10.1016%2fj.jtumed.2017.06.007&partnerID=40&md5=1c1bb3580559edba35f5c486a759a355 VL - 12 ID - 1110 ER - TY - JOUR AB - Matrix metalloproteinases (MMPs) are enzymes with specificity towards extracellular matrix (ECM) components. MMPs, especially MMP-9, have been shown to degrade components of the basal lamina and disrupt the blood-brain barrier (BBB) and thus, contribute to neuroinflammation. In the present study we examined the role of MMP-9 in the foreign body response in the brain. Millipore filters of mixed cellulose ester were implanted into the brain cortex of wild type and MMP-9-null mice for a period of 2 d to 8 wks and the response was analyzed by histology and immunohistochemistry. We observed enhanced and prolonged neuroinflammation in MMP-9-null mice, evidenced by persistence of neutrophils, macrophages/microglia, and reactive astrocytes up to 8 wks post-implantation. In addition, blood vessel density around implants was increased in MMP-9-null mice and detection of mouse serum albumin (MSA) indicated that vessels were leaky. Immunohistochemical and western blot analyses indicated that this defect was associated with the absence of tight junction proteins zonula occludens-1 (ZO-1) and ZO-2 from vessels in proximity to implants. Analysis of brain sections and brain protein extracts revealed that the levels of the pro-inflammatory cytokine interleukin-1β (IL-1β), which is a substrate for MMP-9, were significantly higher in MMP-9-null mice at 8wks post-implantation. Collectively, our studies suggest that increased levels of IL-1β and the delayed repair of BBB are associated with prolongation of the FBR in MMP-9-null mice. © 2009 Elsevier B.V. All rights reserved. AD - Vascular Biology and Therapeutics Program, Departments of Pathology and Biomedical Engineering, Yale University, New Haven, CT 06519, United States AU - Tian, W. AU - Kyriakides, T. R. DB - Scopus DO - 10.1016/j.matbio.2009.02.002 IS - 3 KW - Biomaterials Blood-brain barrier Foreign body response Interleukin Matrix metalloproteinase Neuroinflammation M3 - Article N1 - Cited By :32 Export Date: 10 November 2020 PY - 2009 SP - 148-159 ST - Matrix metalloproteinase-9 deficiency leads to prolonged foreign body response in the brain associated with increased IL-1β levels and leakage of the blood-brain barrier T2 - Matrix Biology TI - Matrix metalloproteinase-9 deficiency leads to prolonged foreign body response in the brain associated with increased IL-1β levels and leakage of the blood-brain barrier UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-67349130899&doi=10.1016%2fj.matbio.2009.02.002&partnerID=40&md5=d61ae71b17a7beee43e60c97f83f37da VL - 28 ID - 1498 ER - TY - JOUR AB - A number of similar macrophage responses to the implantation of various osteoplastic materials into bone defects in humans and laboratory animals have been demonstrated in the present article based on the retrospective analysis of the archival histological material (2008–2016). The presence of osteoplastic materials in a bone regenerate has led to the emergence of giant cells of foreign bodies and osteoclastogenic cells both on the surface of the material and neoformed bone with its subsequent resorption. It was suggested to name this phenomenon “material-associated bone resorption”. © 2019, Privolzhsky Research Medical University. All rights reserved. AD - Department of Bioengineering, Lomonosov Moscow State University, 1/12 Leninskie Gory, Moscow, 119991, Russian Federation Laboratory of Microorganism Nitrogen Fixation, Bach Institute of Biochemistry of the Russian Academy of Sciences, Federal Research Center, “Fundamentals of Biotechnology” of the Russian Academy of Sciences, 33/2 Leninskiy Prospect, Moscow, 119071, Russian Federation Department of Maxillofacial Surgery and Surgical Dentistry, Peoples’ Friendship University of Russia, 6 Miklukho-Maklaya St, Moscow, 117198, Russian Federation Department of Histology, Pathologic Anatomy, and Medical Genetics, I.P. Pavlov Ryazan State Medical University, 9 Vysokovoltnaya St, Ryazan, 390026, Russian Federation Department of Pathologic Anatomy, Peoples’ Friendship University of Russia, 6 Miklukho-Maklaya St, Moscow, 117198, Russian Federation Laboratory for Studies of the Connective Tissue, N.N. Priorov National Medical Research Center of Traumatology and Orthopaedics, Healthcare Ministry of Russia, 10 Priorov St, Moscow, 127299, Russian Federation AU - Bonartsev, A. P. AU - Muraev, A. A. AU - Deyev, R. V. AU - Volkov, A. V. DB - Scopus DO - 10.17691/stm2018.10.4.03 IS - 4 KW - Bone resorption Bone tissue Giant cells of foreign bodies Osteoclasts Osteoplastic materials Regenerative medicine Tissue engineering M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2018 SP - 26-33 ST - Material-associated bone resorption T2 - Sovremennye Tehnologii v Medicine TI - Material-associated bone resorption UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85059320820&doi=10.17691%2fstm2018.10.4.03&partnerID=40&md5=2dc1d35e711638eecb19b6e9307ae9f0 VL - 10 ID - 1095 ER - TY - JOUR AB - The authors present a case of material reaction to suture anchor, which is rarely reported. Leukocyte rate, leukocyte differential, multiple cultures, and gram stain test could not prove infection. A second surgery for exploration of the shoulder joint was performed to reconstruct the rotator cuff without using anchors, and the rotator cuff tear healed after the second surgery. During the second surgery, the bone surrounding the anchors was found to be eroded and substituted with necrotic tissue. The anchors protruded outside the bone. The pathological examination of the necrotic tissue showed multinucleated giant cells of foreign body type, some of which had engulfed minute splinters of particulate foreign material. Either metal- or suture-induced bioreaction is suspected in this case. AD - Orthoped. Ctr. of Southern Illinois, Mount Vernon, IL, United States 4121 Veterans Memorial Drive, Mount Vernon, IL 62864, United States AU - Chow, J. C. Y. AU - Gu, Y. DB - Scopus DO - 10.1016/j.arthro.2004.01.014 IS - 3 KW - Material reaction Suture anchor M3 - Article N1 - Cited By :11 Export Date: 10 November 2020 PY - 2004 SP - 314-316 ST - Material Reaction to Suture Anchor T2 - Arthroscopy - Journal of Arthroscopic and Related Surgery TI - Material Reaction to Suture Anchor UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-1542283761&doi=10.1016%2fj.arthro.2004.01.014&partnerID=40&md5=1c15e158e90fe2e0aa555ad2951fb18d VL - 20 ID - 1634 ER - TY - JOUR AB - Candida species are commensal organisms of different mucous membranes in healthy individuals with the esophagus being a common site of colonization. Candida esophagitis involves the superficial mucosa and transmural invasive candida infection is rare even in immunocompromised patients. Here we report a 49 year-old male who presented with hematemesis after a piece of steak was stuck in his esophagus. He was found on upper endoscopy to have deep esophageal tears, extensive ulcerations and whitish plaque. Biopsies were positive for candida esophagitis and he was subsequently diagnosed with HIV. The patient is a 49 year-old male with history of hypertension that presents with a food impaction in his esophagus after eating steak. He tried to relieve the impaction with self-induced vomiting without relief followed by multiple episodes of hematemesis associated with dysphagia, odynophagia, and severe chest pain. He reports being in usual state of health prior to that incident. He is not on chronic steroids, PPI, or anticoagulant and denies any history of NSAIDs or alcohol abuse. Physical examination was negative for any icteric sclera, palpable crepitus over chest wall or neck, or abdominal findings. CT chest showed no radiopaque foreign body or pneumomediastinum. On emergent EGD the findings were two large submucosal esophageal tears extending 27 to 37 cm from the incisors, diffuse whitish plaques covering the upper esophagus extending to the distal esophagus, and ulcerations of esophageal mucosa but no obvious perforation or food bolus in the esophagus. He was admitted under CT surgery and was kept NPO, on IVF, IV antibiotics and antifungal. Tissue biopsy of the esophagus revealed acute and chronic esophagitis, abundant candida and bacteria. He was positive on HIV screening with a viral load 12,214 and absolute CD4 count 169. A barium esophagram revealed no contrast extravasation. Candida esophagitis is known to occur in immunocompromised hosts but severe complications (i.e perforation, fistula) with esophageal candidiasis are rare and have been mainly reported in diabetic patients with renal transplantations and patients with hematologic malignancy. Unlike eosinophilic esophagitis, food impaction is not often seen in candida esophagitis. The unique highlights of this case are the absence of any prior esophageal or constitutional symptoms and the extent of esophageal mucosal injury sustained from the food impaction in the setting of esophageal candidiasis. (Figure Presented). AD - C. Alexandre, Lenox Hill Hospital/Northwell Health, New York, NY, United States AU - Alexandre, C. AU - Partiula, B. AU - Teagle, K. AU - Mudireddy, P. AU - Caguiat, K. F. DB - Embase DO - 10.1038/ajg.2016.368 KW - anticoagulant agent antifungal agent nonsteroid antiinflammatory agent steroid adult alcohol abuse biopsy case report CD4 lymphocyte count complication contrast medium extravasation diabetic patient diagnosis disease duration eating endoscopy eosinophilic esophagitis esophagus candidiasis esophagus fistula esophagus mucosa esophagus ulcer foreign body hematemesis hematologic malignancy human Human immunodeficiency virus human tissue hypertension immunocompromised patient incisor jaundice kidney transplantation male middle aged neck nonhuman odynophagia perforation physical examination pneumomediastinum sclera screening surgery symptom thorax pain thorax wall virus load vomiting LA - English M3 - Conference Abstract N1 - L612869653 2016-11-10 PY - 2016 SN - 1572-0241 SP - S800-S801 ST - Massive submucosal esophageal tear from meat impaction in candida esophagitis T2 - American Journal of Gastroenterology TI - Massive submucosal esophageal tear from meat impaction in candida esophagitis UR - https://www.embase.com/search/results?subaction=viewrecord&id=L612869653&from=export http://dx.doi.org/10.1038/ajg.2016.368 VL - 111 ID - 394 ER - TY - JOUR AB - It is known that after transurethral resection of the prostate (TUR-P) or a bladder tumor (TUR-BT), necrotizing granuloma formation associated with massive eosinophil accumulation can be detected at the site of the scar, revealing marked eosinophilia. This condition is called post-TUR prostatitis or cystitis. In the present study, we noticed a similar phenomenon in five patients who underwent cholecystectomy, of whom four had gallbladder adenocarcinoma and one had metastatic liver cancer originating from the rectum. We detected necrotizing granulomas with massive eosinophil accumulation, associated with marked eosinophilia. To induce these phenomena, the interval between the first operation (i.e., cholecystectomy) and the second operation (i.e., resection of the hepatic bed and extrahepatic bile duct) is very important. If the interval was 1 week, no granuloma formation was detected. On the other hand, if it was more than 2 weeks, the resected hepatic bed contained necrotizing granulomas with substantial eosinophil accumulation combined with an increase in peripheral eosinophilia (up to 34% in one case). Secondary resection was necessary to induce eosinophilia after cholecystectomy. In this sense, malignancies possessed a relationship with delayed eosinophilia. In the granulomas, some foreign body-type multinucleated giant cells were positive for both anti-interleukin (IL)-5 and CD68 antibodies. In sharp contrast, no eosinophilia was detected after cholecystectomy, with or without hepatic resection consequent to severe adhesion. Clinicians as well as pathologists should keep in mind that these peculiar phenomena of eosinophil accumulation surrounding the necrotizing granulomas and peripheral eosinophilia after cholecystectomy could occur. © 2012 The Japanese Society for Clinical Molecular Morphology. AD - Division of Pathology, Matsuyama-Shimin Hospital, Matsuyama, Ehime 790-0067, Japan Department of Surgery, Matsuyama-Shimin Hospital, Matsuyama, Ehime, Japan Department of Pathology, Kochi Medical School, Kochi University, Kochi, Japan AU - Ohtsuki, Y. AU - Kimura, M. AU - Watanabe, R. AU - Okada, Y. AU - Teratani, Y. AU - Kurabayashi, A. AU - Takeuchi, T. AU - Lee, G. H. AU - Furihata, M. DB - Scopus DO - 10.1007/s00795-011-0555-2 IS - 1 KW - Cholecystectomy Eosinophil Eosinophilia Gallbladder cancer Hepatic bed IL-5 Necrotizing granuloma M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2012 SP - 53-57 ST - Marked infiltration of eosinophils in necrotizing granulomas in the resected hepatic bed after cholecystectomy resulting from gallbladder cancer and metastatic liver cancer is associated with peculiar peripheral eosinophilia T2 - Medical Molecular Morphology TI - Marked infiltration of eosinophils in necrotizing granulomas in the resected hepatic bed after cholecystectomy resulting from gallbladder cancer and metastatic liver cancer is associated with peculiar peripheral eosinophilia UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84858668605&doi=10.1007%2fs00795-011-0555-2&partnerID=40&md5=d7044a132000eb359e4e5f1daabb4a60 VL - 45 ID - 1349 ER - TY - JOUR AB - Background: During a surgical intervention, the patient and the surgical team are placed in a situation of calculated risk. Safe teamwork, work processes that follow quality-assured procedures and use of safety equipment may reduce the incidence of complications and injuries. Objective: The objective of the study was to help achieve best practice and avoid adverse events associated with the set-up and organisation of instruments in the sterile field. We therefore identified the current status in Norwegian surgical departments and investigated correlations with the functional level of the hospital. Method: We used an online survey. The mapping study was undertaken in 16 hospitals and included all health regions and hospitals at all functional levels. Results: All the surgical departments used procedure cards, tray lists, counting procedures and procedures for dealing with sharps injury. Written procedures describing set-up of the instruments in the sterile field were used in four hospitals. Hospitals that provide national or multi-regional services rely on procedures to the greatest extent. Conclusion: The results point to a correlation between the hospitals' service profile and deficiencies when it comes to procedures for the set-up of instruments in the sterile field. We recommend that evidence-based guidelines and procedures be established. Furthermore, we recommend that the evidence base for set-up of instruments in the sterile field be examined. AD - Operasjonssykepleier og universitetslektor, Universitetet i Tromsø -- Norges arktiske universitet Hovedbibliotekar, Universitetet i Tromsø -- Norges arktiske universitet Operasjonssykepleier og førstelektor, Norges teknisk-naturvitenskapelige universitet, Trondheim Professor emeritus, Universitetet i Tromsø -- Norges arktiske universitet AN - 140277893. Language: English. Entry Date: 20191217. Revision Date: 20200324. Publication Type: Article AU - Igesund, Unni AU - Overvåg, Grete AU - Rasmussen, Guri AU - Rekvig, Ole Petter DB - ccm DO - 10.4220/Sykepleienf.2019.78413 DP - EBSCOhost KW - Operating Rooms -- Administration -- Norway Adverse Health Care Event -- Prevention and Control Surgical Equipment and Supplies Perioperative Nursing Nursing Practice, Evidence-Based Human Norway Surveys Surgical Count Procedure Asepsis Sharps Injuries -- Prevention and Control Surgical Patients Patient Safety Clinical Competence Exploratory Research Cross Sectional Studies Structured Questionnaires Descriptive Statistics Protective Devices Practice Guidelines N1 - questionnaire/scale; research; tables/charts. Journal Subset: Continental Europe; Europe; Nursing; Peer Reviewed. NLM UID: 101473387. PY - 2019 SN - 1890-2936 SP - 1-24 ST - Mapping of procedures for set-up of instruments in the sterile field for surgery T2 - Norwegian Journal of Clinical Nursing / Sykepleien Forskning TI - Mapping of procedures for set-up of instruments in the sterile field for surgery UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=140277893&site=ehost-live&scope=site ID - 702 ER - TY - JOUR AB - OBJECTIVE: Preventing retained foreign bodies is critical for patient safety. However, the value of counting surgical instruments and the reliability of the information provided have never been quantified. This study examines the diagnostic characteristics of counting and its impact on surgical costs. METHODS: We examined data from the Medical Event Reporting System-Total HealthSystem (MERS-TH), administrative hospital, and the New York State Cardiac Surgery Report databases (2000-2004). The cost per count discrepancy was examined by studying a cohort of patients undergoing coronary artery bypass graft (CABG) surgery. Linear and logistic multivariable regression models were used for statistical analysis. RESULTS: Of 153,263 operations, there were 1062 count discrepancies. The rate of retained items was 1 of 7000 surgeries or 1 of 70 discrepancy cases. Final count discrepancies identified 77% and prevented 54% of retained items. The sensitivity of counting was 77.2%, specificity was 99.2%, but the positive predictive value was only 1.6%. Count discrepancies increased with surgery duration, late time procedures, and number of nursing teams. Bypass time, intravenous nitroglycerin injections, or myocardial infarction in the previous 24 hours were independent predictors of count discrepancies in CABG surgery. The incremental OR cost for CABG because of a count discrepancy was $932. Nationally, this would amount to an additional $24 million/yr in OR CABG cost. CONCLUSIONS: This study, for the first time, quantifies the diagnostic accuracy of counting and defines the parameters against which alternative strategies of prevention should be measured, before being adopted in standard practice. AD - InCHOIR-International Center for Health Outcomes and Innovation Research, Department of Surgery, Columbia University, 600 W. 168th Street, New York, NY 10032, USA. ne30@columbia.edu AN - 18156916 AU - Egorova, N. N. AU - Moskowitz, A. AU - Gelijns, A. AU - Weinberg, A. AU - Curty, J. AU - Rabin-Fastman, B. AU - Kaplan, H. AU - Cooper, M. AU - Fowler, D. AU - Emond, J. C. AU - Greco, G. DA - Jan DO - 10.1097/SLA.0b013e3180f633be DP - NLM ET - 2007/12/25 IS - 1 KW - Chi-Square Distribution Coronary Artery Bypass/*instrumentation Foreign Bodies/*prevention & control Humans Medical Errors/*prevention & control Operating Rooms Regression Analysis Sensitivity and Specificity *Surgical Instruments LA - eng N1 - Egorova, Natalia N Moskowitz, Alan Gelijns, Annetine Weinberg, Alan Curty, James Rabin-Fastman, Barbara Kaplan, Harold Cooper, Mary Fowler, Dennis Emond, Jean C Greco, Giampaolo U18 HS 11905-03/HS/AHRQ HHS/United States Journal Article Research Support, N.I.H., Extramural United States Ann Surg. 2008 Jan;247(1):13-8. doi: 10.1097/SLA.0b013e3180f633be. PY - 2008 SN - 0003-4932 (Print) 0003-4932 SP - 13-8 ST - Managing the prevention of retained surgical instruments: what is the value of counting? T2 - Ann Surg TI - Managing the prevention of retained surgical instruments: what is the value of counting? VL - 247 ID - 72 ER - TY - JOUR AD - P. Cole, Houston, TX, United States AU - Cole, P. AU - Hollier, L. DB - Embase DO - 10.1097/SCS.0b013e31816ae47a IS - 3 KW - foreign body health care cost health care system human medical practice note priority journal surgical approach surgical technique LA - English M3 - Note N1 - L351786520 2008-07-18 PY - 2008 SN - 1049-2275 SP - 832-833 ST - Managing the prevention of retained surgical instrument: What is the value of counting? T2 - Journal of Craniofacial Surgery TI - Managing the prevention of retained surgical instrument: What is the value of counting? UR - https://www.embase.com/search/results?subaction=viewrecord&id=L351786520&from=export http://dx.doi.org/10.1097/SCS.0b013e31816ae47a VL - 19 ID - 598 ER - TY - JOUR AB - Background: Vesicoureteral reflux is thought to predispose to urinary tract infection and renal scarring, and ureteral reimplantation in childhood remains the gold standard for its treatment. It has been reported that the risk of postrenal failure during pregnancy is increased among women with Politano-Leadbetter ureteral reimplantation. In previous case reports on patients with progressive hydronephrosis and renal failure during pregnancy after ureteral reimplantation, percutaneous nephrostomy was always required, so there has been no information about the clinical management of such patients by ureteral stenting. Here we report a patient with a history of bilateral ureteral reimplantation, in whom severe hydronephrosis during pregnancy was managed with ureteral stents. Case presentation: A primigravida with severe hydronephrosis was referred to us at 29 weeks of gestation. Bilateral Politano-Leadbetter ureteral reimplantation had been performed at the age of 3 years. She was hospitalized immediately, and bilateral ureteral stents were successfully inserted. Post-obstructive diuresis occurred after the stents were placed. Urinary tract infection developed after removal of the urethral catheter 1 week later, but responded to antibiotic therapy and catheter replacement. Labor was induced at 39 weeks of gestation, with vaginal delivery of a healthy male infant. Both stents were found to have spontaneously migrated into the urethra after delivery. Repeat stenting under spinal anesthesia was required to improve postpartum symptoms of back pain and fever. Right distal ureteral obstruction persisted at 6 months after delivery and repeat ureteral reimplantation is planned. Conclusions: General obstetricians will not necessarily pay attention to a history of Politano-Leadbetter ureteral reimplantation, but these patients should undergo careful monitoring of renal function and urinary tract morphology during perinatal care. In the present case, ureteral stenting was effective for postrenal failure during pregnancy after ureteral reimplantation. If ureteral stenting is selected, attention should be paid to post-obstructive diuresis, infection, and stent migration. © 2016 Yoneoka et al. AD - National Hospital Organization Higashi-Ohmi General Medical Center, Department of Obstetrics and Gynecology, 255 Gochi-cho, Higashiohmi, Shiga, 527-0044, Japan Shiga University of Medical Science, Department of Obstetrics and Gynecology, Seta tsukinowa-cho, Otsu, Shiga, 520-2192, Japan Kohka Public Hospital, Department of Urology, 1256 Minakuchichomatsuo, kohka, Shiga, 528-0074, Japan AU - Yoneoka, Y. AU - Kaku, S. AU - Tsuji, S. AU - Yamashita, H. AU - Inoue, T. AU - Kimura, F. AU - Murakami, T. C7 - 70 DB - Scopus DO - 10.1186/s12884-016-0855-6 IS - 1 KW - Postrenal failure Pregnancy Ureteral reimplantation Ureteral stenting M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2016 ST - Management of ureteral stenting for postrenal failure during pregnancy after ureteral reimplantation: A case report T2 - BMC Pregnancy and Childbirth TI - Management of ureteral stenting for postrenal failure during pregnancy after ureteral reimplantation: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84977537543&doi=10.1186%2fs12884-016-0855-6&partnerID=40&md5=0a5cffd118a5b1941dc2ece225cab314 VL - 16 ID - 1188 ER - TY - JOUR AB - Traumatic wounds are always contaminated by bacteria, soil, and other foreign bodies. There is a delicate balance between the deleterious effects of the contaminants and the resistance of the host wound to infection. Successful management of the contaminated wound must include cleansing techniques that remove these contaminants while inflicting minimal injury to the tissue. The number of residual bacteria in the wound after cleansing is a critical determinant of infection. Most traumatic wounds containing >105 bacteria/g tissue are very likely to develop infection. When the bacterial count of a wound is below this level, and after soil and devitalized tissue are removed, wound healing without infection is consistently noted in healthy patients. Fortunately, most soft tissue wounds contain <105 organisms/g tissue. Those exhibiting high levels of bacterial inoculum must be subjected to treatments that reduce the bacterial count, remove all nonvital tissue, and prevent the development of infection. AD - Dept. Plast. Surg., Univ. Virginia, Charlottesville, Va. AU - Edlich, R. F. AU - Rodeheaver, G. T. AU - Stevenson, T. R. DB - Embase Medline IS - 1 KW - antibiotic agent bacterial count debridement major clinical study therapy wound infection LA - English M3 - Article N1 - L8084001 1977-08-10 PY - 1977 SP - 67-74 ST - Management of the contaminated wound T2 - COMPR.THER. TI - Management of the contaminated wound UR - https://www.embase.com/search/results?subaction=viewrecord&id=L8084001&from=export VL - 3 ID - 684 ER - TY - JOUR AB - The fate of a surgical wound is held in a delicate balance between the host's resistance to infection and the causal factors of infection. Considerable insight into this relationship between the host and pathogen can be gained from the results of quantitative bacteriologic measurements. Newer rapid slide techniques have been developed which provide the surgeon with this information within 20 minutes. In most soft tissue injuries, the wound bacterial count gives an accurate prediction of subsequent infection. Wounds combining greater than 10(5) bacteria per gram of tissue are destined to develop infection. When the bacterial count is below that level, the wounds will usually heal per primam without infection. This large number of bacteria required to elicit infection reflects the remarkable ability of soft tissues to resist infection. This state of high resistance to infection can be reduced by several factors which include circulatory embarrassment, tissue injury, dead space, and the presence of foreign bodies (dirt, sutures, drains, etc.). When treating soft tissue injuries, the surgeon must employ specific therapeutic modalities that allow the wound to heal per primam without infection. On the basis of experimental studies supported by clinical experience, the following treatment protocol for soft tissue injuries is recommended. Using strict aseptic technique, the wound must be first anesthetized with 1 per cent Xylocaine to permit painless sound cleansing. All wounds should be subjected to high pressure syringe irrigation to remove bacteria, foreign bodies, and blood clots. When necessary, debridement of all devitalized tissue should be performed with a stainless steel scalpel. Many wounds caused by sharp wounding agents contain no foreign bodies and few bacteria and exhibit considerable resistance to infection. In these wounds, primary closure can be initiated after irrigation without the development of infection. Wounds resulting from impact forces have a diminished resistance to infection and are susceptible to infection by low level of bacterial contamination. Immediate antibiotic treatment of patients with impact injuries subjected to meticulous debridement and cleansing will permit a safe primary closure. In wounds contacted by pus or feces, open wound management followed by delayed primary closure is usually indicated. Antimicrobial prophylaxis is also recommended for patients with such wounds. Ideal postoperative care of all traumatic wounds includes a surgical dressing and immobilization and elevation of the site of injury. AN - 322925 AU - Edlich, R. F. AU - Rodeheaver, G. T. AU - Thacker, J. G. AU - Winn, H. R. AU - Edgerton, M. T. DA - Apr DP - NLM ET - 1977/04/01 IS - 2 KW - Anesthesia, Local Debridement Humans Postoperative Care Suture Techniques Sutures Therapeutic Irrigation Wound Infection/drug therapy Wounds and Injuries/surgery/*therapy LA - eng N1 - Edlich, R F Rodeheaver, G T Thacker, J G Winn, H R Edgerton, M T Journal Article Research Support, U.S. Gov't, Non-P.H.S. United States Clin Plast Surg. 1977 Apr;4(2):191-8. PY - 1977 SN - 0094-1298 (Print) 0094-1298 SP - 191-8 ST - Management of soft tissue injury T2 - Clin Plast Surg TI - Management of soft tissue injury VL - 4 ID - 5 ER - TY - JOUR AB - Purpose To characterise the surgical removal technique of a dislocated dexamethasone implant in the anterior chamber and to gauge its success by analysing corneal transparency and subsequent visual acuity recovery in the postoperative phase. Methods Description of a patient who presented with an anterior chamber dexamethasone implant migration through an inferior iridotomy performed previously for a silicone oil fill in aphakia. Visual acuity had dropped to counting fingers due to marked corneal oedema. Results The implant was removed using a 23-g needle aligned with the axis of the implant through a paracentesis. After the clinical follow-up at 2 months, best-corrected visual acuity had returned to 0.2, which remained stable at the last follow-up at 14 months with an intraocular pressure of 10 mmHg. The corneal oedema resolved completely. Conclusion This novel surgical management of a dexamethasone implant dislocation into the anterior chamber was successful and resulted in no long-term corneal damage when the implant was removed without delay. A repeated Ozurdex injection in patients with previous inferior iridotomy may require prior suturing of the iridotomy. © Georg Thieme Verlag KG Stuttgart. New York. AD - Department of Ophthalmology, University of Lausanne, Hôpital Ophtalmique Jules-Gonin, Ave de France 15, Lausanne, 1004, Switzerland AU - Nguyen, T. L. AU - Wolfensberger, T. J. DB - Scopus DO - 10.1055/a-0808-1847 IS - 4 KW - anterior chamber migration corneal oedema dexamethasone implant M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 412-414 ST - Management of Anterior Chamber Dislocation of a Dexamethasone Implant T2 - Klinische Monatsblatter fur Augenheilkunde TI - Management of Anterior Chamber Dislocation of a Dexamethasone Implant UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064996012&doi=10.1055%2fa-0808-1847&partnerID=40&md5=6cbbbadd324d19c8f9aaebeb4c89d612 VL - 236 ID - 1045 ER - TY - JOUR AD - Department of Emergency Medicine, University of Kansas Health System, Kansas City, KS, United States AU - Lee, A. S. AU - Jackson, B. S. DB - Scopus DO - 10.1016/j.annemergmed.2018.12.006 IS - 6 M3 - Short Survey N1 - Export Date: 10 November 2020 PY - 2019 SP - e79-e80 ST - Man With Finger Pain and Swelling T2 - Annals of Emergency Medicine TI - Man With Finger Pain and Swelling UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065920321&doi=10.1016%2fj.annemergmed.2018.12.006&partnerID=40&md5=326ca9b2037039f2109196c2e17f4a74 VL - 73 ID - 1008 ER - TY - JOUR AB - A 2-year-old female presented acutely with peritonitis and small bowel obstruction. An abdominal radiograph demonstrated a radiopaque foreign body. At laparotomy she was found to have bowel perforations with entero-enteric fistulae caused by four magnets. The magnets were removed, and debridement and closure of the perforations performed. We review our case and highlight this problem to other medical practitioners as a potential cause of significant morbidity and mortality in the paediatric population. © 2013 Springer-Verlag Berlin Heidelberg. AD - Department of Paediatric Surgery, Red Cross War Memorial Children's Hospital, Klipfontein Road, Cape Town 7700, South Africa Department of Paediatric Surgery, Red Cross War Memorial Children Hospital, Klipfontein Road, Cape Town 7700, South Africa AU - Adikibi, B. T. AU - Arnold, M. AU - Van Niekerk, G. AU - Alexander, A. AU - Numanoglu, A. AU - Millar, A. J. W. DB - Scopus DO - 10.1007/s00383-013-3275-y IS - 7 M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2013 SP - 741-744 ST - Magnetic bead toy ingestion: Uses and disuses in children T2 - Pediatric Surgery International TI - Magnetic bead toy ingestion: Uses and disuses in children UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879838147&doi=10.1007%2fs00383-013-3275-y&partnerID=40&md5=92928e41e84e711d2ead7bc09ddd050f VL - 29 ID - 1315 ER - TY - JOUR AB - The sponge matrix allograft model made possible the growth of an AKR lymphoma in a certain percentage of BALB/c mice making progressors (tumor-bearing) and regressors (tumor-rejecting) simultaneously available. Mice bearing either an AKR kidney allograft or a sponge alone were used as controls. The cell population infiltrating the sponge was evaluated 2, 5, 10, 15, and 21 days after subcutaneous implantation. It consisted of macrophages, lymphocytes, and neutrophils. There was no difference between groups on Day 2 and Day 5. From Day 10 onwards, tumor growth was evident with a clear cut separation between progressors and regressors. The latter behaved like the two control groups except for a significant increase in lymphocytes on Day 21. The progressors showed a striking increase in total cell count from Day 10 onwards. Macrophages were the major population with a maximum value of 201 X 106 as compared to 8 X 106 in the regressors; their phagocytic and lysosomal activity remained similar in all groups. The lymphocytes showed no variation in absolute numbers but, because of the high cell count in progressors, their ratio to macrophages reached 1:50 on Day 10, making up only 2% of the cell population. Neutrophils were significantly increased in progressors as compared with the other groups. It can be concluded that in the presence of a foreign body reaction a marked influx of macrophages accompanies allogeneic tumor growth. © 1985 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. AD - Centro de Investigaciones sobre Reproduction, Facultad de Medicina, Universidad de Buenos Aires Section Leucemia Experimental, Institute de Investigaciones Hematologicas Academia National de Medicina, Buenos, Aires, Argentina AU - Barrera, C. N. AU - Mazzolli, A. B. AU - Bustuoabad, O. D. AU - Andreetta, M. AU - Pasqualini, C. D. DB - Scopus DO - 10.3109/07357908509040603 IS - 1 M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 1985 SP - 7-13 ST - Macrophages and tumor growth. II. Cell kinetics at the site of allogeneic tumor growth T2 - Cancer Investigation TI - Macrophages and tumor growth. II. Cell kinetics at the site of allogeneic tumor growth UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021949794&doi=10.3109%2f07357908509040603&partnerID=40&md5=1f12ddb223bb6ce1a97a1ceb3cb07d5a VL - 3 ID - 1752 ER - TY - JOUR AB - To understand further the role of macrophages in the loosening of cemented arthroplasty, several in vitro effects of polymethyl methacrylate (PMMA) particle exposure in these cells were studied. The kinetics of arachidonic acid and derived inflammatory mediator release was characterized following macrophage exposure to either PMMA or control polystyrene particles. Temporal release of radiolabeled products by [14C]arachidonate–labeled cells was determined by sequential scintillation counting. Significant dosedependent release of arachidonic acid mediators by macrophages was observed within half an hour of exposure to either PMMA or styrene particles. Unexposed control cells incubated in media alone did not release detectable amounts of radiolabeled products. The leakage of intracellular lactate dehydrogenase (LDH), a marker of cell injury, was detected spectrophotometrically 4 h following exposure to PMMA but not styrene. PMMA‐induced LDH release was dose depedent. In contrast, polystyrene exposure failed to increase LDH release above unexposed control cells. These in vitro studies reveal that macrophages rapidly released arachidonic acid and derived inflammatory mediators in response to both PMMA and styrene particles. However, cells exposed to PMMA are lethally damaged, as reflected by the subsequent leakage of their intracellular LDH. We propose that a similar sequence of events may occur when macrophages encounter PMMA particles at the bone‐cement interface. This is characteristic of a foreign body granulomatous response. Copyright © 1991 Orthopaedic Research Society AD - Department of Orthopaedic Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States Department of Immunology, Oncology Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States AU - Horowitz, S. M. AU - Gautsch, T. L. AU - Frondoza, C. G. AU - Riley, L., Jr. DB - Scopus DO - 10.1002/jor.1100090313 IS - 3 KW - Aseptic loosening Cemented arthroplasty Macrophages Polymethyl methacrylate M3 - Article N1 - Cited By :83 Export Date: 10 November 2020 PY - 1991 SP - 406-413 ST - Macrophage exposure to polymethyl methacrylate leads to mediator release and injury T2 - Journal of Orthopaedic Research TI - Macrophage exposure to polymethyl methacrylate leads to mediator release and injury UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026153697&doi=10.1002%2fjor.1100090313&partnerID=40&md5=82c667fe952d88f7202db275f5c07425 VL - 9 ID - 1738 ER - TY - JOUR AB - Aseptic lymphocyte-dominated vasculitis-associated lesion (ALVAL) has been used to describe the histological lesion associated with metal-on-metal (M-M) bearings. We tested the hypothesis that the lymphoid aggregates, associated with ALVAL lesions resemble tertiary lymphoid organs (TLOs). Histopathological changes were examined in the periprosthetic tissue of 62 M-M hip replacements requiring revision surgery, with particular emphasis on the characteristics and pattern of the lymphocytic infiltrate. Immunofluorescence and immunohistochemistry were used to study the classical features of TLOs in cases where large organized lymphoid follicles were present. Synchrotron X-ray fluorescence (XRF) measurements were undertaken to detect localisation of implant derived ions/particles within the samples. Based on type of lymphocytic infiltrates, three different categories were recognised; diffuse aggregates (51%), T cell aggregates (20%), and organised lymphoid aggregates (29%). Further investigation of tissues with organised lymphoid aggregates showed that these tissues recapitulate many of the features of TLOs with T cells and B cells organised into discrete areas, the presence of follicular dendritic cells, acquisition of high endothelial venule like phenotype by blood vessels, expression of lymphoid chemokines and the presence of plasma cells. Co-localisation of implant-derived metals with lymphoid aggregates was observed. These findings suggest that in addition to the well described general foreign body reaction mediated by macrophages and a T cell mediated type IV hypersensitivity response, an under-recognized immunological reaction to metal wear debris involving B cells and the formation of tertiary lymphoid organs occurs in a distinct subset of patients with M-M implants. © 2013 Mittal et al. AD - Rheumatology Research Group, Institute of Biomedical Research, MRC Centre for Immune Regulation, University of Birmingham, Birmingham, United Kingdom Royal Orthopedic Hospital, Birmingham, United Kingdom Biomaterials Unit, School of Dentistry, University of Birmingham, Birmingham, United Kingdom School of Metallurgy and Materials, University of Birmingham, Birmingham, United Kingdom School of Engineering and Applied Sciences and Aston Research Centre for Healthy Ageing, University of Aston, Birmingham, United Kingdom Diamond Light Source, Harwell Campus, Didcot, United Kingdom AU - Mittal, S. AU - Revell, M. AU - Barone, F. AU - Hardie, D. L. AU - Matharu, G. S. AU - Davenport, A. J. AU - Martin, R. A. AU - Grant, M. AU - Mosselmans, F. AU - Pynsent, P. AU - Sumathi, V. P. AU - Addison, O. AU - Revell, P. A. AU - Buckley, C. D. C7 - e63470 DB - Scopus DO - 10.1371/journal.pone.0063470 IS - 5 M3 - Article N1 - Cited By :41 Export Date: 10 November 2020 PY - 2013 ST - Lymphoid Aggregates That Resemble Tertiary Lymphoid Organs Define a Specific Pathological Subset in Metal-on-Metal Hip Replacements T2 - PLoS ONE TI - Lymphoid Aggregates That Resemble Tertiary Lymphoid Organs Define a Specific Pathological Subset in Metal-on-Metal Hip Replacements UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84878393933&doi=10.1371%2fjournal.pone.0063470&partnerID=40&md5=532f75b628c5daea4b75e3ab7afc339c VL - 8 ID - 1317 ER - TY - JOUR AB - The human endolymphatic sac was analysed electron microscopically in patients undergoing acoustic Schwannoma surgery or vestibular nerve section. In addition, endolymphatic sacs from cadavers were analysed light microscopically. The results show that the human sac is endowed with a variable number of leucocytes and that there is a continuous recirculation of immunocompetent cells in this area of the inner ear that may be of importance for clearance of the inner ear from foreign substances and microorganisms derived from nearby located infection-prone areas. The possibility in Meniere's disease of a disturbed immunological activity in the sac is discussed. © 1991 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. AD - Department of Otolaryngology, University Hospital, Uppsala, Sweden House Ear Institute, Los Angeles, CA, United States AU - Rask-andersen, H. AU - Danckwardt-lillieström, N. AU - Friberg, U. AU - House, W. DB - Scopus DO - 10.3109/00016489109128039 IS - S485 KW - Endolymphatic sac Human Inner ear Meniere's disease Ultrastructure M3 - Article N1 - Cited By :15 Export Date: 10 November 2020 PY - 1991 SP - 15-17 ST - Lymphocyte-macrophage activity in the human endolymphatic sac T2 - Acta Oto-Laryngologica TI - Lymphocyte-macrophage activity in the human endolymphatic sac UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026362485&doi=10.3109%2f00016489109128039&partnerID=40&md5=bacf4083f941722060c0cdfed4a31fb0 VL - 111 ID - 1739 ER - TY - JOUR AB - A 60-year-old lady with mild fever, blood tinged sputum, and a left upper lung mass had whole body F-18 2-deoxy-D-glucose (FDG) positron emission tomography (PET)-computer tomography (CT) for cancer staging. The PET-CT imaging revealed FDG accumulation in the left upper lung lesion. The histopathology of the left upper lobe lung resection showed a parasite tunnel with necrosis, parasite ova, and foreign body giant cells. After surgery, eosinophiles in the peripheral blood dropped from 20% of white cell counts before operation to 5.5% at 7 weeks postoperation. AD - Department of Nuclear Medicine, Buddhist Tzu Chi General Hospital, Taipei Branch, Taipei, Taiwan. pfkao@yahoo.com.tw AN - 19300059 AU - Kao, P. F. AU - Tsao, T. C. AU - Kuo, K. T. AU - Yue, C. T. AU - Lim, K. R. AU - Chou, Y. H. DA - Apr DO - 10.1097/RLU.0b013e31819a1f28 DP - NLM ET - 2009/03/21 IS - 4 KW - Animals Diagnosis, Differential Female Fluorodeoxyglucose F18/*pharmacology Giant Cells, Foreign-Body/metabolism Granuloma/diagnosis/*diagnostic imaging Humans Lung/*parasitology Lung Neoplasms/diagnosis/*diagnostic imaging Middle Aged Paragonimus Positron-Emission Tomography/*methods Tomography, X-Ray Computed/*methods LA - eng N1 - 1536-0229 Kao, Pan-Fu Tsao, Thomas Chang-Yao Kuo, Kuang-Tai Yue, Chung-Tai Lim, Kung-Rong Chou, Yu-Hsiang Case Reports Journal Article United States Clin Nucl Med. 2009 Apr;34(4):243-4. doi: 10.1097/RLU.0b013e31819a1f28. PY - 2009 SN - 0363-9762 SP - 243-4 ST - Lung parasite ova granuloma mimicking lung malignancy on FDG PET-CT T2 - Clin Nucl Med TI - Lung parasite ova granuloma mimicking lung malignancy on FDG PET-CT VL - 34 ID - 89 ER - TY - JOUR AB - BACKGROUND: Eosinophilic esophagitis (EoE) is the most common cause of dysphagia and esophageal food impaction (EFI) in the USA, Western Europe, and Australia. In Mexico, the uncomplicated form of this disease is infrequent, and prevalence in patients with EFI is unknown. AIMS: To determine the prevalence and causes of EFI, endoscopic and therapeutic aspects, and establish the prevalence of biopsy-proven EoE in patients with EFI. METHODS: Diagnostic upper gastrointestinal endoscopy reports from January 2011 to December 2016 were retrospectively reviewed. Patients with therapeutic procedures, gastrointestinal hemorrhage, or non-food foreign body impaction were excluded. The number of patients with EFI was determined. Additionally, patients with esophageal biopsy were retained for EoE prevalence calculation. The diagnosis of EoE was defined with the presence of eosinophil infiltration count ≥ 15/high-power field with or without typical endoscopic abnormalities. RESULTS: A total of 4700 reports of the same number of patients were selected; 2209 were males (47%) with a mean age of 57.6 ± 12.3 years (range 14-93). We identified 36 patients with EFI (0.76, 95% CI 0.51-1.01), 16 males (44.4%) with a mean age of 54.9 ± 19.7 (range 22-92). Esophageal biopsies were obtained in 17/36 (47.2%) cases. The diagnosis of EoE was confirmed in 2 patients (11.7%). Peptic stenosis was the most frequent cause of EFI. CONCLUSIONS: EoE is an infrequent cause of EFI in the Mexican population (11.7%). EoE had the lowest prevalence compared to that reported in Caucasian populations. The prevalence of EFI was also low. AD - Gastroenterology Service and Department of Internal Medicine, University Hospital "Dr. José E. González" and Medical School, Universidad Autónoma de Nuevo León, Monterrey, Mexico. digarciacompean@prodigy.net.mx. Gastroenterology Service and Department of Internal Medicine, University Hospital "Dr. José E. González" and Faculty of Medicine, Universidad Autónoma de Nuevo León, Madero y Gonzalitos S/N, Monterrey, NL, Mexico. digarciacompean@prodigy.net.mx. Gastroenterology Service and Department of Internal Medicine, University Hospital "Dr. José E. González" and Medical School, Universidad Autónoma de Nuevo León, Monterrey, Mexico. AN - 29594977 AU - García-Compeán, D. AU - González-González, J. A. AU - Duran-Castro, J. J. AU - Herrera-Quiñones, G. AU - Borjas-Almaguer, O. D. AU - Maldonado-Garza, H. J. DA - Jun DO - 10.1007/s10620-018-5037-0 DP - NLM ET - 2018/03/30 IS - 6 KW - Adolescent Adult Aged Aged, 80 and over Biopsy *Deglutition Deglutition Disorders/*epidemiology/pathology/physiopathology/therapy Eosinophilic Esophagitis/*epidemiology/pathology/physiopathology/therapy Esophagoscopy Esophagus/*pathology/physiopathology Female Humans Male Mexico/epidemiology Middle Aged Predictive Value of Tests Prevalence Prognosis Retrospective Studies Risk Factors Young Adult Eosinophilic esophagitis Epidemiology Esophageal food impaction Hispanics LA - eng N1 - 1573-2568 García-Compeán, Diego González-González, José A Duran-Castro, José J Herrera-Quiñones, Gilberto Borjas-Almaguer, Omar D Maldonado-Garza, Héctor J Journal Article United States Dig Dis Sci. 2018 Jun;63(6):1506-1512. doi: 10.1007/s10620-018-5037-0. Epub 2018 Mar 29. PY - 2018 SN - 0163-2116 SP - 1506-1512 ST - Low Prevalence of Biopsy-Proven Eosinophilic Esophagitis in Patients with Esophageal Food Impaction in Mexican Population T2 - Dig Dis Sci TI - Low Prevalence of Biopsy-Proven Eosinophilic Esophagitis in Patients with Esophageal Food Impaction in Mexican Population VL - 63 ID - 211 ER - TY - JOUR AB - Introduction: Staphylococcus aureus frequently causes infections in outpatient and hospital settings and can present as a highly variable entity. Typical manifestations are endocarditis, osteoarticular infections or infection of implanted prostheses, intravascular devices or foreign bodies. A thorough diagnostic evaluation with early focus identification is mandatory to improve patient outcome. Case report: We report a case of a 68-year old patient with a history of double allogeneic stem cell transplant for acute myeloid leukemia who developed a S. aureus bacteremia with dissemination, severe sepsis and lethal outcome due to nasal handkerchief packing after nose bleeding. Conclusion: A thorough medical examination with further diagnostic work-up is most important in S. aureus blood stream infection to identify and eradicate the portal(s) of entry, to rule out endocarditis, to search for spinal abscesses, osteomyelitis or spondylodiscitis. Adherence to management guides for clinicians must be of major importance to achieve optimal quality of clinical care, and thus improve patient outcome. © 2018, Springer-Verlag GmbH Germany, part of Springer Nature. AD - Department I of Internal Medicine, Intensive Care Unit, University Hospital of Cologne, Cologne, Germany Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany Institute of Pathology, University Hospital Cologne, Cologne, Germany AU - Koehler, P. AU - Jung, N. AU - Kochanek, M. AU - Lohneis, P. AU - Shimabukuro-Vornhagen, A. AU - Böll, B. DB - Scopus DO - 10.1007/s15010-018-1221-6 IS - 2 KW - Dissemination Infectious disease consulting Intensive care medicine Superantigen M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2019 SP - 307-311 ST - ‘Lost in Nasal Space’: Staphylococcus aureus sepsis associated with Nasal Handkerchief Packing T2 - Infection TI - ‘Lost in Nasal Space’: Staphylococcus aureus sepsis associated with Nasal Handkerchief Packing UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85053545752&doi=10.1007%2fs15010-018-1221-6&partnerID=40&md5=7b02ffc85ea0c08bd16bc47560c21696 VL - 47 ID - 1018 ER - TY - JOUR AD - Assistant Professors, Department of Plastic Reconstructive and Aesthetic Surgery, Gaziosmanpasa University, Faculty of Medicine, Tokat, Turkey Assistant Professor, Sakarya University, Faculty of Medicine, Department of Biostatistics, Sakarya, Turkey Associate Professor, Gazi Medical School, Department of Histology and Embryology, Ankara, Turkey Professor and Head, Department of Plastic Reconstructive and Aesthetic Surgery, Gaziosmanpasa University AN - 107899573. Language: English. Entry Date: 20140404. Revision Date: 20150819. Publication Type: Journal Article AU - Tuncel, Umut AU - Turan, Aydin AU - Markoc, Fatma AU - Erkorkmaz, Unal AU - Elmas, Cigdem AU - Kostakoglu, Naci DB - ccm DP - EBSCOhost IS - 3 KW - Negative Pressure Wound Therapy Bandages and Dressings Surgical Count Procedure Animal Studies Melon Turkey Rabbits Descriptive Research Kruskal-Wallis Test Analysis of Variance Post Hoc Analysis Mann-Whitney U Test McNemar's Test Data Analysis Software N1 - pictorial; research; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Wound Care. NLM UID: 8912029. PMID: NLM24610559. PY - 2014 SN - 0889-5899 SP - 37-45 ST - Loofah Sponge as an Interface Dressing Material in Negative Pressure Wound Therapy: Results of an In Vivo Study T2 - Ostomy Wound Management TI - Loofah Sponge as an Interface Dressing Material in Negative Pressure Wound Therapy: Results of an In Vivo Study UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107899573&site=ehost-live&scope=site VL - 60 ID - 813 ER - TY - JOUR AB - Purpose: To evaluate long-term results of out-of-the-bag intraocular lens (IOL) implantation. Setting: Department of Ophthalmology, Tenri Yorozu Hospital, Nara, Japan. Methods: This study comprised 22 patients, 13 women and 9 men, who had cataract surgery by phacoemulsification and out-of-the-bag IOL implantation because of a posterior lens capsule rupture. Sixteen patients had in-the-bag IOL implantation in the fellow eye, and these eyes were used as a control group. The IOL's position was determined by ultrasound biomicroscopy (UBM). Anterior chamber flare counts were measured by a laser flare meter. The corneal endothelium was observed by specular microscopy. Results: Mean follow-up after cataract surgery was 35 months ± 22 (SD). The UBM revealed that in the 19 eyes with sulcus-to-sulcus IOL fixation, the optics touched the iris. In 3 eyes, 1 haptic was fixated at the sulcus and the other at the ciliary body. In 2 of these eyes, the optics did not touch the iris. Anterior chamber flare counts in eyes with sulcus-to-sulcus IOL fixation were significantly higher than in eyes with in-the-bag or sulcus-to- ciliary-body fixation (P < .05). There were no statistical differences in corneal endothelial cell counts based on haptic placement. Conclusion: Rubbing between the IOL optic and iris seems to contribute to the high flare counts in eyes with a sulcus-to-sulcus IOL fixation. A larger haptic angle may be needed to prevent contact between the iris and IOL optic in such cases. (C) 2000 ASCRS and ESCRS. AD - Dept. Ophthalmol. Tenri Yorozu Hosp., Tenri, Japan Dept. Ophthalmol. Kurume Univ. F., Kurume, Japan AU - Amino, K. AU - Yamakawa, R. DB - Scopus DO - 10.1016/S0886-3350(99)00345-4 IS - 2 M3 - Article N1 - Cited By :50 Export Date: 10 November 2020 PY - 2000 SP - 266-270 ST - Long-term results of out-of-the-bag intraocular lens implantation T2 - Journal of Cataract and Refractive Surgery TI - Long-term results of out-of-the-bag intraocular lens implantation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033962425&doi=10.1016%2fS0886-3350%2899%2900345-4&partnerID=40&md5=ce7ed6ab8d18108d5a89496da0203547 VL - 26 ID - 1678 ER - TY - JOUR AB - The present study evaluates histological characteristics of the soft tissue response to long-term implantation of Apaceram® discs composed of dense hydroxyapatite in rats. Discs were implanted into the subcutaneous tissue of 76 rats for six to 20 months. Decalcified histological sections stained with haematoxylin and eosin (H and E) and Mallory's azan were examined. Different cell types surrounding implants were counted. The greatest proportion of macrophages was found at six months (13.5 per cent). This proportion gradually decreased to four per cent at 20 months. Small numbers of lymphocytes and foreign body giant cells were observed in every group, but neither neutrophils nor osteogenesis were observed in any specimens. Results of the present study and previous related studies indicate that despite reappearance of a small number of macrophages six months after implantation, Apaceram® is useful for reconstructive surgery. AD - Division of Clinical Otology, Tokushima 770, Japan AU - Dong-Jun, L. I. AU - Ohsaki, K. DB - Scopus DO - 10.1017/s0022215100138411 IS - 8 KW - Hydroxyapatites Rats M3 - Article N1 - Cited By :11 Export Date: 10 November 2020 PY - 1997 SP - 702-706 ST - Long-term observation of subcutaneous tissue reaction to synthetic auditory ossicle (Apaceram®) in rats T2 - Journal of Laryngology and Otology TI - Long-term observation of subcutaneous tissue reaction to synthetic auditory ossicle (Apaceram®) in rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030801790&doi=10.1017%2fs0022215100138411&partnerID=40&md5=a338e80529402035602b2d89e0c6947c VL - 111 ID - 1710 ER - TY - JOUR AB - Purpose: This study was designed to report the long-term complications of iris-claw phakic intraocular lens implantation in a patient with Weill-Marchesani syndrome. Methods: Case report and literature review. Results: A 26-year-old man with a history of glaucoma had bilateral phakic lens implantation for high myopia 10 years previously. Two years later, the left implant dislocated and was repositioned. Slit-lamp examination of both eyes revealed phakic implants of the iris-claw variety. There were moderate iridocorneal adhesions in the areas in which the lens haptics pinched the iris in both eyes and moderate epithelial and stromal edema over the temporal one-third of the left cornea. The crystalline lenses were clear with 3+ phacodonesis OU. Dilated fundus examinations revealed bilateral severe optic nerve cupping. Crystalline lens diameters were measured at 7.5 mm in the right eye and 8 mm in the left. Anterior chamber depths were 2.63 mm OD and 2.40 mm OS. Specular microscopy revealed central endothelial cell counts of 1133 and 587 cells/mm2 OD and OS, respectively. Axial lengths were 23.3 mm OD and 25 mm OS. Gonioscopic examination revealed bilateral angle closure with marked peripheral anterior synechiae. Based on our findings of short stature, shortened and thickened fingers, relatively normal axial length, microspherophakia, high myopia, and glaucoma, we diagnosed the patient with Weill-Marchesani syndrome. Conclusion: Iris claw-lens phakic lenses may be an effective surgical alternative to correct high myopia in select patients; however, it may produce long-term complications in eyes with specific features. Copyright © 2006 by Lippincott Williams & Wilkins. AD - Cornea Service, Wills Eye Hospital, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA, United States Glaucoma Service, Wills Eye Hospital, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA, United States Wills Eye Hospital, 840 Walnut Street, Philadelphia, PA 19107, United States AU - Burakgazi, A. Z. AU - Ozbek, Z. AU - Rapuano, C. J. AU - Rhee, D. J. DB - Scopus DO - 10.1097/01.ico.0000178724.04070.ce IS - 3 KW - Iris-claw lens Phakic intraocular lens Weill-Marchesani syndrome M3 - Review N1 - Cited By :6 Export Date: 10 November 2020 PY - 2006 SP - 361-363 ST - Long-term complications of iris-claw phakic intraocular lens implantation in Weill-Marchesani syndrome T2 - Cornea TI - Long-term complications of iris-claw phakic intraocular lens implantation in Weill-Marchesani syndrome UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33645958897&doi=10.1097%2f01.ico.0000178724.04070.ce&partnerID=40&md5=60b129cba64ec45c28bdf91e847cb8c1 VL - 25 ID - 1585 ER - TY - JOUR AB - A 34-year-old woman had posterior chamber phakic intraocular lens (PCP IOL) implantation to correct high myopia in both eyes. Five years postoperatively, the patient presented with a decrease in visual acuity from central anterior subcapsular cataract formation in both eyes and IOL dislocation in the left eye. In vivo confocal microscopy of the cornea showed markedly decreased endothelial cell density in both eyes and the presence of bright endothelial microdeposits possibly related to pigmentary dispersion. Gonioscopy showed angle pigmentary deposits with no intraocular pressure increase. The patient was successfully treated by removing the PCP IOLs and performing phacoemulsification with in-the-bag IOL implantation in both eyes. This led to a recovery of visual acuity. This case report presents the rare occurrence and surgical management of cataract formation, IOL dislocation, and severe endothelial cell loss as a late complication of PCP IOL implantation. © 2004 ASCRS and ESCRS. AD - Dept. of Med. and Science of Ageing, Section of Ophthalmology, University G. D'Annunzio, Chieti, Italy Ottica Fisiopatologica, Ospedale Clinicizzato, Via dei Vestini, 66100 Chieti, Italy AU - Mastropasqua, L. AU - Toto, L. AU - Nubile, M. AU - Falconio, G. AU - Ciancaglini, M. DB - Scopus DO - 10.1016/j.jcrs.2003.08.012 IS - 4 M3 - Article N1 - Cited By :15 Export Date: 10 November 2020 PY - 2004 SP - 901-904 ST - Long-term complications of bilateral posterior chamber phakic intraocular lens implantation T2 - Journal of Cataract and Refractive Surgery TI - Long-term complications of bilateral posterior chamber phakic intraocular lens implantation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-16544390827&doi=10.1016%2fj.jcrs.2003.08.012&partnerID=40&md5=44cb606dd9bf14040f7438e3b1d5ec75 VL - 30 ID - 1630 ER - TY - JOUR AB - PURPOSE: Synthetic prosthetic materials that are fully absorbable seek to reduce the host foreign body reaction and promote host tissue regeneration. This preclinical trial was designed to analyse, in the long term, the behaviour of two prosthetic meshes, one synthetic and one composed of porcine collagen, in abdominal wall reconstruction. METHODS: Partial defects were created in the abdominal walls of New Zealand rabbits and repaired using a synthetic absorbable mesh (Phasix™) or a non-crosslinked collagen bioprosthesis (Protexa™). After 3, 6, 12 and 18 months, specimens were recovered for light microscopy and collagen expression analysis to examine new host tissue incorporation, macrophage response and biomechanical strength. RESULTS: Both materials showed good host tissue incorporation in line with their spatial structure. At 18 months postimplant, Protexa™ was highly reabsorbed while the biodegradation of Phasix™ was still incomplete. Collagenization of both materials was good. Macrophage counts steadily decreased over time in response to Phasix™, yet persisted in the collagen meshes. At 18 months, zones of loose tissue were observed at the implant site in the absence of herniation in both implant types. The stress-stretch behaviour of Phasix™ implants decreased over time, being more pronounced during the period of 12-18 months. Nevertheless, the abdominal wall repaired with Protexa™ became stiffer over time. CONCLUSION: Eighteen months after the implant both materials showed good compatibility but the biodegradation of Phasix™ and Protexa™ was incomplete. No signs of hernia were observed at 18 months with the stress-stretch relations being similar for both implants, regardless of the more compliant abdominal wall repaired with Protexa™ at short term. AD - Department of Medicine and Medical Specialties, Faculty of Medicine and Health Sciences, University of Alcalá. Ramón y Cajal Health Research Institute (IRYCIS), Madrid, Spain. Networking Biomedical Research Centre on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain. Department of Surgery, Medical and Social Sciences, Faculty of Medicine and Health Sciences, University of Alcalá. Ramón y Cajal Health Research Institute (IRYCIS), Madrid, Spain. Aragon Institute of Engineering Research (I3A), University of Zaragoza, Zaragoza, Spain. Department of Surgery, Medical and Social Sciences, Faculty of Medicine and Health Sciences, University of Alcalá. Ramón y Cajal Health Research Institute (IRYCIS), Madrid, Spain. juanm.bellon@uah.es. Networking Biomedical Research Centre on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain. juanm.bellon@uah.es. AN - 32388587 AU - Pascual, G. AU - Rodríguez, M. AU - Pérez-Köhler, B. AU - Benito-Martínez, S. AU - Calvo, B. AU - García-Moreno, F. AU - Bellón, J. M. DA - May 9 DO - 10.1007/s10029-020-02201-x DP - NLM ET - 2020/05/11 KW - Abdominal wall repair Bioprostheses Collagen mesh Hernia repair Mesh repair Poly-4-hydroxybutyrate (P4HB) LA - eng N1 - 1248-9204 Pascual, G Rodríguez, M Pérez-Köhler, B Benito-Martínez, S Calvo, B García-Moreno, F Bellón, J M Orcid: 0000-0002-1623-4384 SAF2017-89481-P/Spanish Ministry of Economy and Competitiveness./ Journal Article France Hernia. 2020 May 9. doi: 10.1007/s10029-020-02201-x. PY - 2020 SN - 1248-9204 ST - Long term comparative evaluation of two types of absorbable meshes in partial abdominal wall defects: an experimental study in rabbits T2 - Hernia TI - Long term comparative evaluation of two types of absorbable meshes in partial abdominal wall defects: an experimental study in rabbits ID - 248 ER - TY - JOUR AB - Background. Despite their degradation in the host organism, the benefits of collagen bioprostheses remain unclear. This study addresses the absorption and long-term host tissue incorporation of several collagen biomeshes. Material and methods. Partial ventral hernial defects created in the abdominal wall of rabbits were repaired using the crosslinked meshes Permacol® or CollaMend®, or the non-crosslinked Surgisis®, Tutomesh® or Strattice®. After 90 and 180 days of implant, morphological studies and morpho-metric analysis of the thickness of the meshes were performed. Immunofluorescence confocal microscopy combined with differential interference contrast (DIC) imaging was used to distinguish newly formed collagen from that comprising the mesh. The macrophage response was examined by immunohisto-chemistry. Results. At 90 days, the thinner non-crosslinked biomeshes Tutomesh and Surgisis were more fully degraded with much of their collagen replaced with loose connective tissue. By 180 days, both implants had been practically fully absorbed. In contrast, in Strattice only the outermost third was infiltrated by neoformed tissue. On both surfaces of the crosslinked meshes, a fibrous capsule with host cells lining its perimeter was observed at both time points, though at 180 days these cells had penetrated the mesh interior. At both implant times, Strattice showed the higher expression of collagen type I while collagen III expression was similar for all the meshes. The non-crosslinked materials elicited lower macrophage counts at both time points, significantly so for Strattice. The macrophage response decreased over time for all the meshes but Surgisis. Conclusions. Strattice, the thicker, more compacted non-crosslinked mesh showed the best balance between tissue incorporation and absorption while eliciting a minimal foreign-body reaction in the long-term. AD - Department of Surgery, Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Alcalá University, Alcalá de Henares, Madrid, Spain Department of Medical Specialities, Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Alcalá University, Alcalá de Henares, Madrid, Spain AU - Pascual, G. AU - Sotomayor, S. AU - Pérez-López, P. AU - Buján, J. AU - Bellón, J. M. DB - Scopus IS - 1 KW - Abdominal wall repair Bioprosthesis Collagen mesh Hernia repair M3 - Article N1 - Cited By :12 Export Date: 10 November 2020 PY - 2014 SP - 139-149 ST - Long term behavior of biological prostheses used as abdominal wall substitutes T2 - Histology and Histopathology TI - Long term behavior of biological prostheses used as abdominal wall substitutes UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84890943694&partnerID=40&md5=a2c8313492beddec63bb7f0a5469076c VL - 29 ID - 1295 ER - TY - JOUR AB - We studied the tissue response for periprosthetic pseudosynovial tissue in seven patients with a purulent endoprosthetic infection and six patients with common prosthesis loosening, using specific monoclonal antibodies in avidin-biotin-peroxidase complex staining. In infected cases, proline 4-hydroxylase positive fibroblasts dominated the stroma of the vascularized periprosthetic connective tissue, whereas ;diffuse local infiltrations of mononuclear cells characterized the cellular histological overview. Local cellular response consisted of CD11b and MHC locus II antigen-positive immunoreactive monocytes/macrophages and of T lymphocytes, mostly of the CD4 subset. Only a few CD25-positive cells could be detected. The local cellular response in six patients with prosthesis loosening of nonbacterial origin was mild, showing a sparse perivascular infiltration of CD11b- and Ia-positive monocytes/macrophages and CD4/CD8-positive T lymphocytes in a proportion of 2:1. Only occasional CD15- or lactoferrin-positive neutrophils and CD25-positive lymphocytes could be detected. Our results from chronically infected joint replacements suggest that neutrophils, being virtually absent in the tissue compartment, do not contribute to pathological events in the "pseudojoint" cavity, whereas local tissue response consists of a mononuclear inflammatory cell reaction of a macrophage-dependent foreign-body type. © 1994 Springer-Verlag. AD - Fourth Department of Medicine, Helsinki University Central Hospital, Unioninkatu 38, Helsinki, SF-00170, Finland Orthopaedic Hospital of the Invalid Foundation, Helsinki, Finland Peijas-Rekola Hospital, Vantaa, Finland Hospital for Joint Diseases, Orthopaedic Institute, New York, United States Department of Anatomy, University of Helsinki, Helsinki, Finland AU - Nordström, D. AU - Santavirta, S. AU - Antti-Poika, I. AU - Konttinen, Y. T. DB - Scopus DO - 10.1007/BF00441625 IS - 3 M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 1994 SP - 159-163 ST - Local immune inflammatory response to infected total hip and knee replacements T2 - Archives of Orthopaedic and Trauma Surgery TI - Local immune inflammatory response to infected total hip and knee replacements UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028210111&doi=10.1007%2fBF00441625&partnerID=40&md5=f119fc5a3d147f804623911c2f62f11a VL - 113 ID - 1726 ER - TY - JOUR AB - We report a case of liver abscess and portal vein thrombosis, which occurred due to diverticulitis at the terminal ileum in a 59-year-old man. The patient underwent a barium fluoroscopic examination 1 month before presenting to our hospital. He also showed liver dysfunction due to thrombosis at the superior mesenteric and portal veins. His inflammation gradually subsided after the initiation of treatment, but the recovery was not sufficient. Thus, surgery was performed. The patient condition improved after surgery and he was discharged. Barium examinations are relatively safe, but can sometimes cause severe adverse effects in patients with certain risk factors, and an appropriate diagnosis and treatment are necessary when symptoms appear. © 2017 The Japanese Society of Internal Medicine. AD - Department of Gastroenterology, Japan Community Healthcare Organization Tokyo Shinjuku Medical Center, Japan Department of Surgery, Japan Community Healthcare Organization Tokyo Shinjuku Medical Center, Japan AU - Kubo, H. AU - Asai, G. AU - Haraguchi, K. AU - Shibahara, Y. AU - Kihara, T. AU - Yamakawa, G. AU - Kira, F. AU - Higashi, H. AU - Morishita, S. AU - Fujie, H. AU - Matsumoto, M. AU - Shimura, W. DB - Scopus DO - 10.2169/internalmedicine.9223-17 IS - 23 KW - Barium Diverticulitis Liver abscess Portal vein thrombosis Superior mesenteric vein thrombosis M3 - Article N1 - Export Date: 10 November 2020 PY - 2017 SP - 3255-3259 ST - Liver abscess and portal vein thrombosis due to ileal diverticulitis mediated by barium fluoroscopy T2 - Internal Medicine TI - Liver abscess and portal vein thrombosis due to ileal diverticulitis mediated by barium fluoroscopy UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85037045678&doi=10.2169%2finternalmedicine.9223-17&partnerID=40&md5=60ea8a31243d34c80daa135950754c29 VL - 56 ID - 1162 ER - TY - JOUR AB - Pelvic-penetrating injuries are rare but often spectacular and constitute formidable management problems. Most of the patients suffered from organ or vascular damages; however, neurological lesion in combination with pelvic impalement was seldom reported. This paper highlights a unique case of pelvic impalement through the sacrum with cauda equina injury. A 50-year-old construction worker was impaled in the pelvis because of an accidental fall on a steel bar. The surgical treatment of the injury and the medical management of complications are described in detail. The patient made a good recovery, although he has functional deficits related to the concomitant cauda equina injury. Our case emphasizes the importance of appropriate neurological diagnosis when providing no magnetic resonance imaging but a fuzzy x-ray computed tomography because of a metal object in situ and of individualized surgical management during therapeutic process. © 2013 Wolters Kluwer Health, Inc. All rights reserved. AD - Department of Orthopaedics, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, Sichuan, 610041, China AU - Ye, J. AU - Kong, Q. AU - Yang, T. DB - Scopus DO - 10.1097/WNQ.0000000000000006 IS - 1 KW - accidental fall cauda equina syndrome Penetrating pelvic injury steel bar transsacral impalement M3 - Review N1 - Export Date: 10 November 2020 PY - 2015 SP - 124-127 ST - Literature review and clinical presentation of pelvic impalement by steel bar causing cauda equina syndrome T2 - Neurosurgery Quarterly TI - Literature review and clinical presentation of pelvic impalement by steel bar causing cauda equina syndrome UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84923641891&doi=10.1097%2fWNQ.0000000000000006&partnerID=40&md5=1abf541befbd6461839357988b8d8c3b VL - 25 ID - 1243 ER - TY - JOUR AB - The study was designed to evaluate the frequency and type of count errors, and examine the circumstances under which they occur, in operating theatres in Sydney hospitals. One hundred and forty count errors were documented across seven hospital sites during a three-year period, of which 64% were 'documentation' errors and 36% were 'lost item' errors. The majority of count errors occurred during elective surgery (79%), of up to four hours' duration (74%), and involving just one instrument nurse and one circulating nurse (80%). Perioperative nurses reported that complex surgeries, rushing, instrument handling and team performance issues detracted from their capacity to count and document accurately. The study recommends better management of nurses' fatigue during long and complex surgeries. There is a clear need for increasing the number of circulating nurses for busy lists with multiple, short surgeries, and limiting the number of items added to the sterile field during surgery. Within the busy, pressured surgical team, a whole-of-team commitment to count procedures must be adopted and cooperation and communication must be maintained. While there are set count procedures in place, each operating suite is responsible for encouraging compliance with accepted practice and supporting and sustaining instrument and circulating nurses in their efforts to eliminate count errors. AD - St Vincent's Hospital Darlinghurst, NSW National Centre for Clinical Outcomes Research (NaCCOR), The Australian Catholic University, VIC St Vincent's Hospital, Darlinghurst, NSW St. Vincent's & Mater Health Sydney & South Eastern Sydney and Illawara Area Health Service AN - 104964300. Language: English. Entry Date: 20110128. Revision Date: 20150820. Publication Type: Journal Article AU - Butler, Margaret AU - Ford, Rosemary AU - Boxer, Elaine AU - Sutherland-Fraser, Sally DA - 2010 Spring DB - ccm DP - EBSCOhost IS - 3 KW - Health Care Errors Retained Instruments Surgical Count Procedure Surgical Instruments Adult Content Validity Descriptive Research Descriptive Statistics Documentation Exploratory Research Health Care Errors -- Classification Health Care Errors -- Etiology Hospitals Human Middle Age New South Wales Perioperative Nursing Qualitative Studies Quantitative Studies Questionnaires Registered Nurses Retrospective Design Self Report Thematic Analysis N1 - research; tables/charts. Journal Subset: Australia & New Zealand; Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. PY - 2010 SN - 1448-7535 SP - 6-10 ST - Lessons from the field: an examination of count errors in the operating theatre T2 - ACORN: The Journal of Perioperative Nursing in Australia TI - Lessons from the field: an examination of count errors in the operating theatre UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104964300&site=ehost-live&scope=site VL - 23 ID - 861 ER - TY - JOUR AB - This paper deals with the author's war-time experience of traumatic lesions of the chest, with particular reference to missile tracts and extra-pleural haematomata. He emphasizes that in the majority of cases in which these lesions occur they are ill-defined radiologically and difficult to visualize on the film, as both missile tracts and extra-pleural haematomata are frequently obscured by concomitant pleural effusion or pulmonary collapse. Missile tracts are divided into 'solid' and 'air-containing', and clinical descriptions of both types are given accompanied by illustrative examples from a series of X-ray films. The percentage incidence of these lesions has not yet been worked out accurately, but a rough count of 500 cases of penetrating wounds of the chest shows radiologically recognizable lesions as follows: solid tracts 10 per cent, air-containing tracts 2 per cent. The lipiodol investigation of these tracts follows the same general lines as for sinuses and fistulae elsewhere in the body, but the value of screen examination of the lipiodol-filled tract is emphasized, with careful observation during the act of coughing in order to demonstrate any possible connection with a bronchus. Extra-pleural haematomata derive their importance from the fact that if adequately demonstrated radiologically, treatment can usually be effected without involving what may well be a normal pleural cavity. Thus when, as is often the case, they contain bone fragments, metallic foreign bodies, or are infected, all necessary surgical treatment can be carried out without opening the pleura, a performance that calls for careful radiological localisation of the lesion as an essential preliminary. The author in his series estimates the percentage incidence of extra-pleural haematomata at 1 per cent. AU - Hodson, C. DB - Embase Classic IS - 210 KW - iodinated poppyseed oil bone bronchus coughing examination fistula foreign body injury atelectasis neuropathic joint disease penetrating trauma pleura pleura cavity pleura effusion solid surgery thorax war X ray film LA - English M3 - Article N1 - L280498277 1945-12-01 PY - 1945 SN - 0007-1285 SP - 176-182 ST - Lesions found in traumatic chest T2 - British Journal of Radiology TI - Lesions found in traumatic chest UR - https://www.embase.com/search/results?subaction=viewrecord&id=L280498277&from=export VL - 118 ID - 700 ER - TY - JOUR AB - Background: Paraurethral leiomyoma is a rare benign hormone-dependent neoplasm of mesenchymal origin affecting women. Clinical evidence is variable but it tends to be asymptomatic or associated with the sensation of a foreign body, while urinary symptoms are rarely described. Excision of the mass is the recommended treatment and diagnosis is confirmed by pathological analysis to rule out the presence of a sarcoma. A case of paraurethral leiomyoma associated with dysuria, dyspareunia and obstructive voiding symptoms is reported here. Case Report: A 28-year-old woman, presented with dysuria, dyspareunia and occasional urinary retention, associated with the presence in the vaginal introitus of a palpable, smooth, solid mass located above the urethral orifice just beneath the clitoris. Transvaginal ultrasonography showed a 25×25 mm hypoechoic mass, highly vascularized on colored Doppler imaging. The voiding cystogram did not show communication of the mass with the lower urinary tract but a constriction of the urethra was revealed. Axial T1-and T2-weighted MRI scans were performed and a neoplasm with signal similar to that of a uterine fibroid, compressing the urethra, was diagnosed. The patient underwent surgical excision of the mass, which was easily performed by blunt dissection, after 4-cm longitudinal incision of the anterior vaginal wall. The pathological analysis showed the presence of a paraurethral leiomyoma with less than 1 mitotic figure per 10 high-power fields. The patient had no immediate postoperative complications, the urethral catheter was removed two days after surgery and micturition was immediately restored. Urinary flow evaluation performed one month later revealed a normal Qmax nomogram and dyspareunia had disappeared. Discussion: Distinction between urethral, paraurethral, and anterior vaginal wall leiomyoma may be difficult due to their close anatomical proximity. Differential diagnosis of these lesions includes urethral diverticulum, Skene duct abscess, Bartolini gland cyst, Gartner duct cyst, vaginal wall cyst and urethral carcinoma. The literature supports the excision of these lesions to determine the mitotic count, which differentiates leiomyoma from locally recurrent or metastatic leiomyosarcoma, and this can help to predict the possibility of recurrence, which is extremely rare if there are fewer than 5 mitotic figures per 10 high-power fields. The case described here was unusual because of the symptoms (usually, there is paraurethral mass and increased urinary frequency, while voiding dysfunction and urinary retention, as presented here, are very rare) and the young age of the patient (28 years of age while the average age of patients at presentation is 47 years, with a range from 39 to 62 years). AD - G. Perugia, Urologia, Dipartimento di Scienze Ginecologiche-Ostetriche Ed Urologiche, Roma, Italy AU - Perugia, G. AU - Di Viccaro, D. AU - Chinazzi, A. AU - Antonini, F. AU - De Cillis, A. AU - Borgoni, G. AU - Croce, F. AU - Liberti, M. DB - Embase IS - 5 KW - hormone leiomyoma urethra oncology society patient cyst dyspareunia excision female neoplasm dysuria urine retention leiomyosarcoma urinary frequency sensation foreign body diagnosis case report solid clitoris transvaginal echography imaging cystography interpersonal communication ligation nuclear magnetic resonance imaging uterus myoma dissection incision postoperative complication urethral catheter surgery micturition nomogram differential diagnosis urethra diverticulum abscess urethra carcinoma sarcoma LA - English M3 - Conference Abstract N1 - L70437707 2011-06-18 PY - 2011 SN - 0250-7005 SP - 1856-1857 ST - Leiomyoma of the female urethra T2 - Anticancer Research TI - Leiomyoma of the female urethra UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70437707&from=export VL - 31 ID - 542 ER - TY - JOUR AD - J.R. Gunn and Associates of Greenwood, IN AN - 105053090. Language: English. Entry Date: 20100827. Revision Date: 20200619. Publication Type: Journal Article AU - Gunn, J. R. DB - ccm DO - 10.1097/01.orn.0000384193.57245.a8 DP - EBSCOhost IS - 4 KW - Malpractice -- Legislation and Jurisprudence Perioperative Nursing -- Legislation and Jurisprudence Cesarean Section Documentation Intraoperative Complications Medical Records Retained Instruments -- Legislation and Jurisprudence Surgical Count Procedure Ureter -- Injuries N1 - case study; pictorial. Journal Subset: Double Blind Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 101308226. PY - 2010 SN - 1933-3145 SP - 35-39 ST - Legal issue in perioperative nursing T2 - OR Nurse TI - Legal issue in perioperative nursing UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105053090&site=ehost-live&scope=site VL - 4 ID - 840 ER - TY - JOUR AN - 6921817 AU - Regan, W. A. DA - Aug DP - NLM ET - 1982/08/01 IS - 3 KW - Female Femoral Fractures/*diagnosis Foreign Bodies Humans *Hysterectomy Indiana Infant, Newborn Infant, Newborn, Diseases/*diagnosis Maine *Malpractice *Surgical Instruments LA - eng N1 - Regan, W A Case Reports Journal Article United States Regan Rep Nurs Law. 1982 Aug;23(3):3. PY - 1982 SN - 0034-3196 (Print) 0034-3196 SP - 3 ST - Legal case briefs for nurses. IN: Pediatrics: pre-discharge injury; ME: Surgery: sponge count error T2 - Regan Rep Nurs Law TI - Legal case briefs for nurses. IN: Pediatrics: pre-discharge injury; ME: Surgery: sponge count error VL - 23 ID - 7 ER - TY - JOUR AB - A subclavian artery-esophageal fistula usually occurs on the right side of an aberrant subclavian artery. It also rarely appears in the site between a non-aberrant subclavian artery and the esophagus due to the ingestion of a foreign body. Upper gastrointestinal bleeding in the case of a subclavian artery-esophageal fistula is rare but often fatal. Here, we report on a 62-year-old male patient with a left subclavian artery-esophageal fistula complicated by hemorrhagic shock. He swallowed a foreign body at a birthday party. An upper gastrointestinal endoscopy indicated a paper star lodged at 20 cm from the incisors, inducing a kissing esophageal ulcer around the esophageal sphincter. One month later, he suffered an unusually strong episode of hematemesis. Subsequently, a computed tomography angiography was performed and demonstrated a left subclavian artery-esophageal fistula. Finally, the fistula induced by the ingestion of a paper star was successfully treated by endovascular stent grafting. © Author(s) 2016. AD - Division of Gastroenterology, Kuang Tien General Hospital, Taichung, 433, Taiwan Department of Medical Laboratory Science and Biotechnology, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 404, Taiwan Department of Biotechnology, Asia University, Wufeng, Taichung, 413, Taiwan AU - Lin, C. S. AU - Lin, C. W. C7 - e69 DB - Scopus DO - 10.7603/s40681-016-0018-0 IS - 3 KW - Gastrointestinal bleeding Hemorrhagic shock Subclavian artery-esophageal fistula M3 - Article N1 - Export Date: 10 November 2020 PY - 2016 SP - 31-33 ST - Left subclavian artery-esophageal fistula induced by a paper star: A case report T2 - BioMedicine (Netherlands) TI - Left subclavian artery-esophageal fistula induced by a paper star: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84981742331&doi=10.7603%2fs40681-016-0018-0&partnerID=40&md5=a372ae3affef05f5a2221be031b996af VL - 6 ID - 1171 ER - TY - JOUR AB - INTRODUCTION: Leaving a foreign object (retained surgical item, or RSI) during surgery involving the abdominal cavity and pelvis minor is a relatively frequent, underestimated phenomenon which is dangerous to the health of the patient and the legal security of the medical personnel. These adverse events are easy to avoid through the use of appropriate means of prevention. The aim of the present paper is the collection of epidemiological data and determination of risk factors, symptomatology, health effects, and prevention methods associated with RSIs. MATERIAL AND METHODS: Analysis of global scientific publications in the databases PubMed, ClinicalKey, Google Scholar, ScienceDirect, and Scopus related to the subject of RSIs. RESULTS: The frequency of RSI incidents ranges from 1 to 10 in 10,000 surgeries, which results in at least one case in an average multispeciality hospital on a yearly basis. The items most frequently left behind include soft foreign objects, such as swabs and bandages (90%). Risk factors include emergency surgical procedures, high patient BMI, significant loss of blood during surgery, and neglect in counting the material and surgical tools. The postoperative course, although in many cases asymptomatic, may be complicated by inflammation, bleeding, or perforation, leading to the necessity of a second operation and, in 2 to 4% of cases, even ending in death. Imaging tests are effective diagnostic tools. Effective methods of preventing RSIs are based on checklists and systems for counting and monitoring the location of material and tools. CONCLUSIONS: The globally occurring problem of RSIs requires education of the operating block personnel regarding risk factors and identification with elimination of adverse events of this type. Diagnostics based on imaging should take into account non-specific complaints resulting from a possible oligosymptomatic course. An RSI should not be regarded as a medical error. Changes in the perception of the phenomenon aim aimed at minimising the legal liability of the staff in the event of leaving a foreign object in a patient's body. AD - Studenckie Koło Naukowe "Bezpieczna medycyna", Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu. Katedra Medycyny Sądowej, Zakład Prawa Medycznego Uniwersytetu Medycznego im. Piastów Śląskich we Wrocławiu. AN - 31849358 AU - Szymocha, M. AU - Pacan, M. AU - Anufrowicz, M. AU - Jurek, T. AU - Rorat, M. DA - May 15 DO - 10.5604/01.3001.0013.2024 DP - NLM ET - 2019/12/19 IS - 6 KW - Abdominal Cavity/*surgery Foreign Bodies/*epidemiology/prevention & control Humans Medical Errors/prevention & control/*statistics & numerical data Patient Care Team Patient Safety/*statistics & numerical data Risk Factors Surgical Instruments Surgical Procedures, Operative/*statistics & numerical data adverse event foreign object gossypiboma never event retained foreign object LA - eng N1 - 2299-2847 Szymocha, Marcin Pacan, Marta Anufrowicz, Mateusz Jurek, Tomasz Rorat, Marta Journal Article Review Poland Pol Przegl Chir. 2019 May 15;91(6):35-40. doi: 10.5604/01.3001.0013.2024. PY - 2019 SN - 0032-373x SP - 35-40 ST - Leaving a foreign object in the body of a patient during abdominal surgery: still a current problem T2 - Pol Przegl Chir TI - Leaving a foreign object in the body of a patient during abdominal surgery: still a current problem VL - 91 ID - 236 ER - TY - JOUR AB - Background: Tertiary metropolitan referral center, Australia. Introduction: The use of a Fobi ring to prevent pouch dilatation is sometimes used in Roux-en-Y gastric bypass (RYGB). Recently, it has been extrapolated to laparoscopic sleeve gastrectomy (LSG) procedures by placing a fixed-ring band a few centimeters below the gastro-esophageal junction (GEJ). Objectives: What is the consequence if a patient develops a leak? Methods: Over 18 months, all patients with either a conventional LSG or a fixed-ring banded sleeve gastrectomy (BLSG) who presented with a proven leak complication were included. The management approaches along with the surgical, endoscopic and percutaneous procedures used were examined. Results: 6 patients had a BLSG leak and 6 had a LSG leak. All patients had leak resolution. There was no significance difference in body mass index (BMI), time to leak, initial white cell count (WCC) and C-reactive protein (CRP) levels between the two groups. LSG patients required a median of 2 endoscopic procedures (range 1-3). Stents were deployed in three patients. All BLSG patients required a single surgical intervention with laparoscopic washout, drainage, removal of band +/-feeding jejunostomy. One stent was deployed in one BLSG patient. BLSG leak resolution was demonstrated at 34±12 days versus 85±12 days in the LSG group (p<0.05). Conclusion: The BLSG is a new modification of the sleeve gastrectomy procedure. This study presents a management strategy for leak resolution employed in BLSG patients. The presence of a foreign body as a persistent nidus of infection mandates band removal. AD - J. Tan, Sir Charles Gairdner Hospital, Perth, Australia AU - Tan, J. AU - Foo, J. AU - Balshaw, J. AU - Tan, M. DB - Embase DO - 10.1007/s11695-017-2774-7 IS - 1 KW - C reactive protein endogenous compound adult body mass case report clinical article complication conference abstract controlled study endoscopy feeding female foreign body gene expression human infection jejunostomy laparoscopic sleeve gastrectomy leukocyte count male postoperative complication stent surgery LA - English M3 - Conference Abstract N1 - L620637320 2018-02-15 PY - 2017 SN - 1708-0428 SP - 747 ST - Leaks in fixed-ring banded sleeve gastrectomies: A management approach. Post-operative complications T2 - Obesity Surgery TI - Leaks in fixed-ring banded sleeve gastrectomies: A management approach. Post-operative complications UR - https://www.embase.com/search/results?subaction=viewrecord&id=L620637320&from=export http://dx.doi.org/10.1007/s11695-017-2774-7 VL - 27 ID - 370 ER - TY - JOUR AB - BACKGROUND: The use of a Fobi ring to prevent pouch dilation is sometimes used in Roux-en-Y gastric bypass (RYGB). Recently, it has been extrapolated to laparoscopic sleeve gastrectomy (LSG) procedures by placing a fixed-ring band a few centimeters below the gastroesophageal junction (GEJ). OBJECTIVES: What is the consequence if a patient develops a leak? SETTING: Tertiary metropolitan referral center, Australia. METHODS: Over 18 months, all patients with either a conventional LSG or a fixed-ring banded sleeve gastrectomy (BLSG) who presented with a proven leak complication were included. The management approaches along with the surgical, endoscopic, and percutaneous procedures used were examined. RESULTS: Six patients had a BLSG leak and 6 had a LSG leak. All patients had leak resolution. There was no significant difference in body mass index (BMI), time to leak, initial white cell count (WCC), and C-reactive protein (CRP) levels between the 2 groups. LSG patients required a median of 2 endoscopic procedures (range: 1-3). Stents were deployed in 3 patients. All BLSG patients required a single surgical intervention with laparoscopic washout, drainage, removal of band±feeding jejunostomy. One stent was deployed in 1 BLSG patient. BLSG leak resolution was found at 34±12 days versus 85±12 days in the LSG group (P< .05). CONCLUSION: The BLSG is a new modification of the sleeve gastrectomy procedure. This study presents a management strategy for leak resolution employed in BLSG patients. The presence of a foreign body as a persistent nidus of infection mandates band removal. AD - Department of General Surgery, Sir Charles Gairdner Hospital, Nedlands, Perth, Western Australia. University of Notre Dame, Fremantle, Western Australia. Department of General Surgery, Sir Charles Gairdner Hospital Nedlands, Perth, Western Australia. Department of General Surgery, Sir Charles Gairdner Hospital Nedlands, Perth, Western Australia. Electronic address: jthtan1@gmail.com. AN - 28545915 AU - Foo, J. W. AU - Balshaw, J. AU - Tan, M. H. L. AU - Tan, J. T. H. DA - Aug DO - 10.1016/j.soard.2017.03.031 DP - NLM ET - 2017/05/27 IS - 8 KW - Adult Body Mass Index Device Removal/methods Drainage/methods Enteral Nutrition/statistics & numerical data Esophagogastric Junction/surgery Female Foreign Bodies/etiology/surgery Gastrectomy/*adverse effects Gastric Balloon Gastroplasty/*adverse effects Gastroscopy/*methods Humans Laparoscopy/*adverse effects Length of Stay/statistics & numerical data Male Obesity, Morbid/surgery Prosthesis-Related Infections/etiology/surgery Reoperation/methods/statistics & numerical data Retrospective Studies Stents Surgical Wound Dehiscence/etiology/*surgery Banded sleeve gastrectomy Bariatric surgery Complications Fixed-ring sleeve gastrectomy Gastric leak Minimizer ring Sleeve gastrectomy Sleeve gastrectomy leak LA - eng N1 - 1878-7533 Foo, Jonathan W Balshaw, James Tan, Michael H L Tan, Jeremy T H Evaluation Study Journal Article United States Surg Obes Relat Dis. 2017 Aug;13(8):1259-1264. doi: 10.1016/j.soard.2017.03.031. Epub 2017 Apr 4. PY - 2017 SN - 1550-7289 SP - 1259-1264 ST - Leaks in fixed-ring banded sleeve gastrectomies: a management approach T2 - Surg Obes Relat Dis TI - Leaks in fixed-ring banded sleeve gastrectomies: a management approach VL - 13 ID - 193 ER - TY - JOUR AB - We present the case of a patient with cardiac tamponade secondary to late intrapericardial migration of a disrupted ventriculo-atrial shunt (VAS). A 48-year old woman was referred for cardiac tamponade. She had a history of congenital hydrocephalus with implantation of a VAS (Codman®) in 1994. The initial neurological examination was normal. Tomodensitometry showed a discontinuity of the VAS at the cervical level with its distal part floating in the pericardium. Immediate surgery through sternotomy allowed the draining of the pressurized translucid liquid. The distal part of the VAS was extracted and the perforation site on the right ventricle was sutured. The patient showed no neurological trouble 3 months after operation. Surprisingly, cardiac tamponade was not related to bleeding but to the accumulation of translucid liquid whose gross aspect and biochemistry were very suggestive of cerebrospinal fluid (CSF). We hypothesize that a fibrin sheath had developed around the VAS at the time of its disconnection and acted as a fibrous tunnel allowing continued CSF drainage through its distal part. Surgical strategies to prevent late VAS disconnection should be considered at the time of implantation. © 2012 The Author. AD - Department of Cardiac Surgery, Institut de Cardiologie, University Pierre et Marie Curie, 47-83 Boulevard de l'Hôpital, 75013 Paris, France Department of Neurosurgery, Groupe Hospitalier Pitié-Salpêtrière, University Pierre et Marie Curie, Paris, France Department of Cardiology, Centre Hospitalier Auxerre, Auxerre, France AU - Mastroianni, C. AU - Chauvet, D. AU - Ressencourt, O. AU - Kirsch, M. DB - Scopus DO - 10.1093/icvts/ivs443 IS - 3 KW - Cardiac tamponade Ventriculo-atrial shunt M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2013 SP - 391-393 ST - Late ventriculo-atrial shunt migration leading to pericardial cerebrospinal fluid effusion and cardiac tamponade T2 - Interactive Cardiovascular and Thoracic Surgery TI - Late ventriculo-atrial shunt migration leading to pericardial cerebrospinal fluid effusion and cardiac tamponade UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84874333429&doi=10.1093%2ficvts%2fivs443&partnerID=40&md5=89e47358df2ec708ee2fa7e8f5c922bc VL - 16 ID - 1329 ER - TY - JOUR AB - Introduction: In the great majority of cases of long-standing intrathoracic foreign bodies, patients are asymptomatic. Rarely, transthoracic foreign bodies cause problems when left lodged in the pulmonary parenchyma. Early removal is required only in cases of pneumonia, lung abscess, empyema or proximity to a major organ. When left in place, bullets or other foreign bodies become surrounded over time by fibrous tissue and do no harm. Only few cases in literature reported symptoms that occur decades after the injury. Case report: We report a case of 37 years old Hispanic female with past medical history of Hypertension who presented to the emergency department with hemoptysis 10 years after having a bullet injury to her chest when she was on her home roof in Dominican Republic. Patient remained asymptomatic for 10 years and no intervention was done at the time of the incident. However, she started having recurrent small amount of hemoptysis along with retrosternal non-radiating chest pain and exertional shortness of breath for the past year. The only abnormal physical findings were the old healed scar at left 2nd intercostal space in midclavicular line and minimal rhonchi in left upper and lower lung fields on auscultation. Laboratory testing was normal including platelet count, coagulation test, kidney functions, urine studies and sputum smears for malignancy and infection. The chest x ray showed bullet fragment in left upper lung field and Computerized Tomography Angiography of the chest showed bullet fragment with surrounding infiltration in left upper lobe, peri-hilar ground-glass infiltrates secondary to pulmonary hemorrhage. Patient was hospitalized and bronchoscopy was done that showed bloody secretions in the apical segment of LUL which was successfully suctioned without an obvious source of bleed. Thoracic surgery was consulted but the plan was made to manage conservatively. Patient was discharged and was followed up afterwards for 1 year. No more episodes of hemoptysis were documented. Conclusion: Complications caused by foreign bodies retained in the lungs may arise many years after the initial injury. Among the symptoms and signs, hemoptysis is the most common. Our patient has the symptoms 10 years after the initial bullet injury. The management depends upon clinical scenario, if the patient has persistent chest wall pain or persistent purulent expectoration or hemoptysis, foreign body should be removed otherwise with minor and self-resolving episodes, conservative management is the treatment of choice. AD - P. Kaur, Internal Medicine, New York Medical College, St. Joseph Regional Medical Center, Paterson, NJ, United States AU - Kaur, P. AU - Elshimy, G. AU - Singh, B. DB - Embase IS - MeetingAbstracts KW - glass adult auscultation blood clotting test bodily secretions bronchoscopy cancer patient cancer recurrence case report clinical article complication computed tomographic angiography conference abstract conservative treatment Dominican Republic dyspnea emergency ward female foreign body gunshot injury hemoptysis Hispanic hospital discharge human human tissue hypertension infection kidney function laboratory test lung hemorrhage malignant neoplasm medical history physical examination platelet count scar sputum smear thorax pain thorax radiography thorax surgery urine LA - English M3 - Conference Abstract N1 - L622966346 2018-07-16 PY - 2018 SN - 1535-4970 ST - Late presentation of retained intrathoracic foreign body T2 - American Journal of Respiratory and Critical Care Medicine TI - Late presentation of retained intrathoracic foreign body UR - https://www.embase.com/search/results?subaction=viewrecord&id=L622966346&from=export VL - 197 ID - 357 ER - TY - JOUR AB - We report an unusual case of ventriculoperitoneal (VP) shunt intrathoracic migration, associated with massive symptomatic hydrothorax. The VP shunt was inserted 10 years before presentation, after hemorrhagic hydrocephalus caused by prenatal intraventricular hemorrhage. The pleural fluid was drained via tube thoracostomy and the shunt was externalized, with full resolution of symptoms and signs. The patient was subsequently managed with shunt revision with drainage into the abdominal cavity. We review the 10 pediatric cases of cerebrospinal fluid hydrothorax reported in the literature and discuss the mechanism of shunt tip migration. Pleural effusion secondary to VP shunt insertion is a rare and potentially life-threatening occurrence, and it should be suspected in any patient with a VP shunt and respiratory distress. © 2012 by Lippincott Williams & Wilkins. AD - Department of Pediatrics, University of Tel Aviv, Dana Children's Hospital, 6 Weizman St, Tel Aviv 64239, Israel Department of Pediatric Neurosurgery, Dana Children's Hospital, Tel Aviv University, Israel Department of Pediatrics, University of Toronto, Hospital for Sick Children, Toronto, Canada AU - Glatstein, M. M. AU - Roth, J. AU - Scolnik, D. AU - Haham, A. AU - Rimon, A. AU - Koren, L. AU - Constantini, S. DB - Scopus DO - 10.1097/PEC.0b013e3182447dce IS - 2 KW - cerebrospinal fluid hydrothorax pleural effusion respiratory distress ventriculoperitoneal shunt M3 - Review N1 - Cited By :14 Export Date: 10 November 2020 PY - 2012 SP - 180-182 ST - Late presentation of massive pleural effusion from intrathoracic migration of a ventriculoperitoneal shunt catheter: Case report and review of the literature T2 - Pediatric Emergency Care TI - Late presentation of massive pleural effusion from intrathoracic migration of a ventriculoperitoneal shunt catheter: Case report and review of the literature UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84857158448&doi=10.1097%2fPEC.0b013e3182447dce&partnerID=40&md5=35f8f249873cef2c05dcef71c5888318 VL - 28 ID - 1383 ER - TY - JOUR AB - Introduction: Dermal fillers are used for multiple cosmetic indications including gluteal and thigh augmentation. Complications, although infrequent, are increasing due to the dramatic growth of dermal filler use. Our aim was to describe how the complication of infected silicone granulomas can present following lower limb augmentation. Methods: Two cases presented with pain, oedema, and erythema at the site of previous silicone filler injection, following a considerable delay after the last injection (range 4-7 years). We collected data on their biochemistry, haematology, histology, microbiology, and imaging at the time of presentation. Results: Complications included prolonged cellulitis with recurrent abscesses at sites of previous silicone dermal filler injection. Histology revealed infiltration of chronic inflammatory cells suggestive of silicone granuloma in both cases. Patients were reluctant to divulge use of cosmetic fillers or failed to recognise their significance given the time delay making diagnosis difficult. Delayed or recurring infections can suggest the presence of atypical organisms and we present the first reported case of silicone granuloma infection with Propionibacterium acnes. Conclusions: Microorganisms can induce immune-mediated hypersensitivity and are believed to be the trigger for delayed activation of a quiescent foreign body to a granulomatous reaction. The substantial time delay between injection and reaction must be recognised and may be attributable to atypical microorganisms or biofilm formation. Previous antibiotic use can affect expedient microbiological diagnosis and treatment requires close collaboration with microbiologists. It is important that clinicians are aware of these important complications which are becoming more common with increased use of filler augmentation. © The Author(s) 2018. AD - Department of Orthopaedics, Royal Free Hospital, London, United Kingdom The Welsh Centre for Burns and Plastic Surgery, Morriston Hospital, Swansea, United Kingdom Department of Pathology, Royal Free Hospital, London, United Kingdom AU - Jessop, Z. M. AU - Welck, M. AU - Zinser, E. AU - Garlick, N. AU - Hopkins, S. DB - Scopus DO - 10.1177/1179544118759020 KW - dermal filler lower limb augmentation Silicone granuloma M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2018 ST - Late Presentation of Infected Silicone Granulomas in the Lower Limb T2 - Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders TI - Late Presentation of Infected Silicone Granulomas in the Lower Limb UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85060206504&doi=10.1177%2f1179544118759020&partnerID=40&md5=d3ed585c65515cf81e9952d88ec14360 VL - 11 ID - 1089 ER - TY - JOUR AB - Plombage, a variant of collapse therapy for patients with pulmonary tuberculosis that uses a variety of foreign materials, was undertaken until the 1950s before the invention of effective antimicrobial therapy. Complications related to previous plombage procedures are not uncommon. Management of these complications can be challenging. We report a patient presenting with extrusion of plombage 59 years later and managed successfully with removal of the plomb and pectoral muscle flap transposition. © 2010 Published by European Association for Cardio-Thoracic Surgery. AD - Department of Cardiothoracic Surgery, The Townsville Hospital, 100 Angus Smith Drive, Doulas, QLD, Australia Department of Cardiothoracic Surgery, Fremantle Hospital, Fremantle, Perth, WA 6959, Australia AU - Yadav, S. AU - Sharma, H. AU - Iyer, A. DB - Scopus DO - 10.1510/icvts.2009.220699 IS - 5 KW - Pectoral muscle flap Plombage Tuberculosis M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2010 SP - 808-810 ST - Late extrusion of pulmonary plombage outside the thoracic cavity T2 - Interactive Cardiovascular and Thoracic Surgery TI - Late extrusion of pulmonary plombage outside the thoracic cavity UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77954627674&doi=10.1510%2ficvts.2009.220699&partnerID=40&md5=b04437f098b60eead1cad82a05c5e787 VL - 10 ID - 1459 ER - TY - JOUR AB - Objective The aim was to analyse the incidence and presentation of carotid patch inflammatory reactions following carotid endarterectomy (CEA). Methods This was a cohort study using a prospectively maintained database. All patients who underwent elective CEA at a tertiary vascular centre between 2002 and 2016 were included. Computed tomography scan angiogram, duplex scan, and leucocyte scintigraphy were used to assess patients with suspected inflammatory patch complications. Re-intervention procedures and outcomes were noted. Histopathology and organisms cultured from the harvested material during re-intervention were assessed. Results During the study period, 633 patients underwent elective CEA. Fifty-one underwent eversion endarterectomy: 111 did not require a patch, whereas 471 patients had a patch repair. Four hundred and twenty eight had a Dacron patch repair and 43 a biological patch. Eight patients returned with late Dacron patch inflammatory complications (1.3% of all CEA and 1.9% of Dacron patch closures) after a period ranging from 18 months to 7 years (mean 4.1 ± 2.1 years). Seven of the eight patients underwent surgical re-intervention, and the eighth patient was deemed high surgical risk. One patient underwent a vein bypass, three had vein patch repair, one required internal carotid artery (ICA) ligation after patch excision, and two were managed by debridement, with omohyoid and sternomastoid muscle covering of the patch. The patient who required ICA ligation suffered a fatal stroke. The remaining patients had a satisfactory outcome. All patients showed evidence of foreign body reaction in pathological examination with no pathological organism cultured from swabs or tissue harvested during surgery. Conclusion Late wound complications after CEA may be related to inflammatory reaction of the Dacron patch rather than infection. Infection should be excluded first. Reconstruction with vein is effective. However, debridement with sternomastoid and omohyoid muscle covering of the patch may be considered in high risk patients after exclusion of infection with regular follow-up. © 2017 European Society for Vascular Surgery AD - Western Vascular Institute (WVI), Department of Vascular and Endovascular Surgery, University College Hospital, Galway (UCHG), Newcastle Road, Galway, Ireland Department of Histopathology, University College Hospital, Galway (UCHG), Newcastle Road, Galway, Ireland Department of Vascular Surgery, Galway Clinic, Doughiska, Galway, Ireland AU - Alawy, M. AU - Tawfick, W. AU - ElKassaby, M. AU - Shalaby, A. AU - Zaki, M. AU - Hynes, N. AU - Sultan, S. DB - Scopus DO - 10.1016/j.ejvs.2017.06.015 IS - 4 KW - Carotid endarterectomy Dacron Foreign body reaction Infection Patch M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2017 SP - 423-429 ST - Late Dacron Patch Inflammatory Reaction after Carotid Endarterectomy T2 - European Journal of Vascular and Endovascular Surgery TI - Late Dacron Patch Inflammatory Reaction after Carotid Endarterectomy UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85026254829&doi=10.1016%2fj.ejvs.2017.06.015&partnerID=40&md5=da5210dce587c8292eaf8bcfd15fae61 VL - 54 ID - 1119 ER - TY - JOUR AB - BACKGROUND: Laparoscopy is widely used as a tool in many clinical situations allowing for diagnosis and/or surgical management in a minimally invasive fashion. Most laparoscopic cases are ambulatory and allow patients to recover quickly. Nonetheless, attention to surgical technique is paramount to avoid both short and long term complications. CASE: A 32-year-old woman had a laparoscopy and a reported left salpingoophorectomy for benign disease of the ovary in September, 1994. Shortly thereafter, in January, 1995, she was diagnosed with an intrauterine pregnancy and delivered in October of 1995 by spontaneous vaginal delivery. The pregnancy and delivery were both uncomplicated. The patient presented four weeks postpartum with clinical suspicion of appendicitis. However, at the time of laparotomy, the patient was found to have a retained foreign body from her prior laparoscopy in the right lower quadrant with a pelvic abscess and evidence of prior right salpingoophorectomy. The appendix appeared grossly normal. CONCLUSION: Laparoscopy is a safe, effective modality for various surgical and gynecologic conditions. Although laparoscopy is usually done on an outpatient basis, complications can manifest several weeks or months later. This case illustrates and reminds us of the importance of adherence to surgical laparoscopic principles. These include direct visualization when removing equipment and a complete count of surgical instrumentation to confirm the integrity of such at the end of each procedure. AD - University of Miami/Jackson Memorial Hospital Department of Obstetrics and Gynecology, FL 33136, USA. AN - 9876653 AU - Mendez, L. E. AU - Medina, C. C2 - PMC3015230 DA - Jan-Mar DP - NLM ET - 1997/01/01 IS - 1 KW - Abdomen, Acute/etiology Abscess/diagnosis/*etiology/surgery Adult Fallopian Tubes/surgery Female Follow-Up Studies Foreign Bodies/diagnosis/*etiology/surgery Humans Laparoscopy/*adverse effects *Omentum Ovarian Cysts/surgery Ovariectomy/adverse effects/methods Peritoneal Diseases/diagnosis/*etiology/surgery Time Factors Treatment Outcome LA - eng N1 - 1938-3797 Mendez, L E Medina, C Case Reports Journal Article JSLS. 1997 Jan-Mar;1(1):79-81. PY - 1997 SN - 1086-8089 (Print) 1086-8089 SP - 79-81 ST - Late complication of laparoscopic salpingoophorectomy: retained foreign body presenting as an acute abdomen T2 - Jsls TI - Late complication of laparoscopic salpingoophorectomy: retained foreign body presenting as an acute abdomen VL - 1 ID - 25 ER - TY - JOUR AB - In the non-industrialized countries of Africa and Asia obstetric fistulas are more frequently caused by prolonged labour, whereas in countries with developed healthcare systems they are generally the result of complications of gynaecological surgery or, rarely, benign pathologies like inflammation or foreign bodies. A 22-year-old woman was brought to the gynaecology clinic because of foul-smelling vaginal discharge. On pelvic examination a ring-like foreign body was impacted between the anterior and posterior vaginal wall. MRI scan confirmed the presence of a cylindrical foreign body in the vagina and the patient revealed that she had involuntarily' inserted a plastic bubble bath cap into the vagina. At surgery removal of the cap was difficult and at the end of the manoeuver evidence of a huge urethro-vesicovaginal fistula occurred. The patient was discharged with bilateral ureteral stents and suprapubic catheter. After 3 months we performed an end-to-end anastomotic urethroplasty to repair the urethral avulsion and restored the bladder/ trigonal and vaginal/cervical defects with 3 layers of sutures; 3 months later the patient had no complaints. Complex genital fistulas represent an extremely debilitating morbidity. In our case, a vaginal approach was successful, but the choice between an abdominal or vaginal approach depends on the surgeon's experience and training. © 2015 S. Karger AG, Basel. AD - Urology Clinic, University of Verona, Piazzale L.A. Scuro 10, Verona, IT37134, Italy AU - D'Elia, C. AU - Curti, P. AU - Cerruto, M. A. AU - Monaco, C. AU - Artibani, W. DB - Scopus DO - 10.1159/000365421 IS - 1 KW - Foreign body Genital fistula Incontinence Urethro-vaginal fistula Vesico-vaginal fistula M3 - Review N1 - Cited By :5 Export Date: 10 November 2020 PY - 2015 SP - 120-124 ST - Large Urethro-Vesico-Vaginal Fistula due to a Vaginal Foreign Body in a 22-Year-Old Woman: Case Report and Literature Review T2 - Urologia Internationalis TI - Large Urethro-Vesico-Vaginal Fistula due to a Vaginal Foreign Body in a 22-Year-Old Woman: Case Report and Literature Review UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84939651054&doi=10.1159%2f000365421&partnerID=40&md5=6c3ecb432579fc5d5af40c03fbf0d098 VL - 95 ID - 1221 ER - TY - JOUR AB - Case Report: A 71-year-old man was referred to our centre for obstructive lower urinary tract symptoms (LUTS) and history of a vague, chronic discomfort in the right groin and testis since many years. Prostate-specific antigen (PSA) level was 12 ng/dl. The diagnostic work up revealed a Gleason score 4+4=8 adenocarcinoma of the prostate. No bone metastases were present. At the preoperative computed tomography (CT) scan, there was no evidence of pathologic pelvic lymph nodes on the left side of the pelvis, while a 3.0×5.0 cm solid mass of unknown nature was found close to the right iliac vessels (Figure 1). The central area was dishomogeneous as due to necrotic tissue; in turn, the peripheral, hypodense crown contained several hyperdense spots. The densitometric aspect of the prostate was highly irregular. The patient was then scheduled for open radical prostatectomy and extended pelvic lymph node dissection (ePLND). During the right lymph node dissection, a solid mass, firmly adherent to the right iliac vessels, was carefully isolated and removed intact. The intraoperative examination revealed a retained surgical sponge with a peripheral fibrous pseudocapsule resulting from an inflammatory foreign-body reaction, known in literature as gossypiboma or textiloma (Figure 2) (1). Indeed, the patient underwent emergency surgery for incarcerated inguinal hernia 30 years before. Discussion and Conclusion: Although more infrequent with standardized surgical counting (2), gossypibomas can still be either asymptomatic occasional findings or, if not promptly diagnosed, life threatening causes of intestinal obstruction and acute abdomen. Moreover, they can simulate intra-abdominal gastrointestinal stromal tumors making the differential diagnosis challenging. The problem of retained surgical items affects both open and minimally invasive surgery (3). Prevention is a key aspect to ensure the maximal safety of surgical patients. (Figure Presented). AD - G. Siena, Department of Urology, Careggi Hospital, University of Florence, Florence, Italy AU - Siena, G. AU - Campi, R. AU - Mari, A. AU - Minervini, A. AU - Carini, M. AU - Lapini, A. AU - Serni, S. DB - Embase IS - 6 KW - prostate specific antigen prostatectomy hernioplasty society oncology pelvis human male lymph node dissection pelvis lymph node patient solid prostate bone metastasis testis Gleason score case report intestine obstruction adenocarcinoma differential diagnosis minimally invasive surgery safety computer assisted tomography examination diagnosis inguinal region tissues surgical sponge foreign body reaction emergency surgery inguinal hernia acute abdomen gastrointestinal stromal tumor lower urinary tract symptom prevention surgical patient L1 - internal-pdf://3829176425/3615.full.pdf LA - English M3 - Conference Abstract N1 - L72287061 2016-05-31 PY - 2015 SN - 0250-7005 SP - 3691-3692 ST - Large pelvic gossypiboma diagnosed at the time of radical prostatectomy 30 years after inguinal hernioplasty T2 - Anticancer Research TI - Large pelvic gossypiboma diagnosed at the time of radical prostatectomy 30 years after inguinal hernioplasty UR - https://www.embase.com/search/results?subaction=viewrecord&id=L72287061&from=export VL - 35 ID - 430 ER - TY - JOUR AB - We report a case of a 73-year-old woman who presented to general surgery with a tender lump in the groin 5 years after insertion of a tension-free vaginal tape. The lesion was thought to be an incarcerated inguinal hernia. Emergency surgical exploration revealed a 7×5×4 cm soft tissue mass which was adherent to the external inguinal ring, emanating from the end of the tension-free vaginal tape at the level of the symphysis pubis. Resection and histological examination revealed a central track of granulation tissue with a surrounding foreign body inflammatory response. The surgery was complicated by an infected seroma requiring surgical drainage and antibiotic therapy, following which the patient made a full recovery. Large foreign body reaction is a rare but an important complication of tension-free vaginal tapes and may be mistaken for a groin hernia or lymphadenopathy. © 2011 The International Urogynecological Association. AD - Department of Surgery and Cancer, Imperial College, Chelsea and Westminster Hospital, 369 Fulham Road, London SW9 9NH, United Kingdom Department of Obstetrics and Gynaecology, Chelsea and Westminster Hospital, 369 Fulham Road, London SW9 9NH, United Kingdom AU - Von Roon, A. C. AU - Letchworth, P. AU - Stafford, M. DB - Scopus DO - 10.1007/s00192-011-1412-5 IS - 9 KW - Complications Foreign body reaction Tension-free vaginal tape M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2011 SP - 1193-1195 ST - Large foreign body reaction to tension-free vaginal tape masquerading as inguinal hernia T2 - International Urogynecology Journal TI - Large foreign body reaction to tension-free vaginal tape masquerading as inguinal hernia UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-80052486379&doi=10.1007%2fs00192-011-1412-5&partnerID=40&md5=2ae98fd323bcca47ea59aa895e782b00 VL - 22 ID - 1431 ER - TY - JOUR AB - INTRODUCTION: Ileal perforation due to fish bone is a rare event. The condition is difficult to diagnose due to lack of specific clinical features and low sensitivity of imaging techniques. We report a case of ileal perforation by a fish bone that was detected laparoscopically and managed nonsurgically. CASE PRESENTATION: A 45-year-old Sinhalese man presented with acute onset right iliac fossa pain and fever for three days. On examination, he had significant right iliac fossa tenderness and guarding. His white cell count and C-reactive protein level were elevated and an ultrasound scan was indicative of a bowel mass formation. A clinical diagnosis of acute appendicitis was made and laparoscopic appendicectomy was scheduled. At initial survey, a thin spike-like structure was retrieved from the bowel mass, which was revealed to be a fish bone. Our patient was managed with antibiotics only and did not develop any complications. CONCLUSIONS: Ileal perforation due to fish bone is a rare condition that can mimic common conditions like appendicitis. Preoperative diagnosis is rarely made. The slow process of fish bone migration results in concomitant sealing of the perforation, reducing contamination. Use of laparoscopy may be useful in diagnosing this condition and preventing the morbidity of laparotomy in these patients. AD - Department of Surgery, University of Kelaniya, North Colombo Teaching Hospital, Ragama, 11010, Sri Lanka. pramodh@sltnet.lk. District General Hospital, Homagama, 10200, Sri Lanka. ckpathirana@yahoo.com. AN - 25888949 AU - Chandrasinghe, P. C. AU - Pathirana, C. K. C2 - PMC4349716 DA - Feb 25 DO - 10.1186/s13256-015-0526-7 DP - NLM ET - 2015/04/19 KW - Appendectomy Appendicitis/diagnosis Diagnosis, Differential Foreign Bodies/*diagnosis Humans Ileum/*surgery Intestinal Perforation/*diagnosis/therapy Laparoscopy/*methods Male Middle Aged LA - eng N1 - 1752-1947 Chandrasinghe, Pramodh Chitral Pathirana, Chandrasiri Karapitiya Case Reports Journal Article J Med Case Rep. 2015 Feb 25;9:43. doi: 10.1186/s13256-015-0526-7. PY - 2015 SN - 1752-1947 SP - 43 ST - Laparoscopically detected and nonsurgically managed ileal perforation by an ingested fish bone: a case report T2 - J Med Case Rep TI - Laparoscopically detected and nonsurgically managed ileal perforation by an ingested fish bone: a case report VL - 9 ID - 160 ER - TY - JOUR AB - INTRODUCTION: Ingestion of a toothpick, both accidentally and intentionally, is a rare event. PRESENTATION OF CASE: We present the case of a 42-years old man who was admitted to the emergency department at our Institution presenting with a 5-days history of right sided abdominal pain. Laboratory blood count reported leukocytosis and alteration of principal inflammation index; at the abdominal ultrasound no signs of perforation or collection were described. DISCUSSION: Indication to surgery was posed and an explorative laparoscopy was performed. The presence of local peritonitis at the right colonic flexure secondary to a full thickness bowel perforation caused by a toothpick was found. There was also an acute phlegmonous appendicitis. A laparoscopic appendectomy and a full-thickness double running suture of the perforation were performed. CONCLUSION: Awareness about dangers of ingested toothpicks needs to be taken and the intestinal track/trace of the toothpick is mandatory until its expulsion. AD - Department of General Surgery, Emergencies and New Technologies, Baggiovara Civil Hospital, Modena, Italy. Electronic address: casonipattacini.gian@aou.mo.it. Department of General Surgery, Emergencies and New Technologies, Baggiovara Civil Hospital, Modena, Italy. AN - 32958447 AU - Casoni Pattacini, G. AU - Pecchini, F. AU - Mullineris, B. AU - De Maria, R. AU - Trapani, V. AU - Francescato, A. AU - Piccoli, M. DA - Sep 10 DO - 10.1016/j.ijscr.2020.09.056 DP - NLM ET - 2020/09/23 KW - Foreign bodies Laparoscopic suture Wooden toothpick LA - eng N1 - Casoni Pattacini, Gianmaria Pecchini, Francesca Mullineris, Barbara De Maria, Roberto Trapani, Vincenzo Francescato, Alice Piccoli, Micaela Case Reports Netherlands Int J Surg Case Rep. 2020 Sep 10:S2210-2612(20)30728-8. doi: 10.1016/j.ijscr.2020.09.056. PY - 2020 SN - 2210-2612 (Print) 2210-2612 ST - Laparoscopic treatment of right colic flexure perforation by an ingested wooden toothpick T2 - Int J Surg Case Rep TI - Laparoscopic treatment of right colic flexure perforation by an ingested wooden toothpick ID - 261 ER - TY - JOUR AB - Presently described is case of a 52-year-old man who was admitted to the emergency department with 3-day history of epigastric pain. Abdominal examination revealed diffuse tenderness and muscle guarding. Plain abdominal X-ray showed free subdiaphragmatic air. The patient underwent diagnostic laparoscopy with presumptive diagnosis of peptic ulcer perforation. Laparoscopy showed several inflamed, edematous jejunal loops with proximal obstruction and perforation by an impacted fish bone. Completely intracorporeal resection and anastomosis using laparoscopic linear stapler was performed and segment of resected bowel was removed through trocar site. Postoperative period was uneventful, and the patient was discharged on fourth day. © 2016 TJTES. AD - Department of General Surgery, Bakirköy Dr. Sadi Konuk Training and Research Hospital, İstanbul, Turkey Department of General Surgery, Yedikule Surp Pırgic Armenian Hospital Foundation, İstanbul, Turkey Department of General Surgery, Bağcılar Training and Research Hospital, İstanbul, Turkey AU - Dural, A. C. AU - Çelik, M. F. AU - Yiğitbaş, H. AU - Akarsu, C. AU - Doğan, M. AU - Alış, H. DB - Scopus DO - 10.5505/tjtes.2016.88137 IS - 6 KW - Fish bone Foreign body ingestion Perforation Small bowel M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2016 SP - 572-574 ST - Balık kılçığı yutulmasına bağlı gelişen ince bağırsak perforasyonunun laparoskopik rezeksiyon ve anastomozu T2 - Ulusal Travma ve Acil Cerrahi Dergisi TI - Laparoscopic resection and intracorporeal anastomosis of perforated small bowel caused by fish bone ingestion UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84997666896&doi=10.5505%2ftjtes.2016.88137&partnerID=40&md5=7872625e9727a03f6831f2e4e9f71be3 VL - 22 ID - 1167 ER - TY - JOUR AB - Sacral colpopexy may be complicated by mesh exposure, and the surgical treatment of mesh exposure typically results in minor postoperative morbidity and few delayed complications. A 75-year-old woman presented 7 years after a laparoscopic sacral colpopexy, with Mersilene mesh, with an apical mesh exposure. She underwent an uncomplicated transvaginal excision and was asymptomatic until 8 months later when she presented with vaginal drainage and a sacral abscess. This was successfully treated with laparoscopic enterolysis, drainage of the abscess, and explantation of the remaining mesh. Incomplete excision of exposed colpopexy mesh can lead to ascending infection and sacral abscess. Laparoscopic drainage and mesh removal may be considered in these patients. been reported to have only minor postoperative complications and abdominal excisions are more likely to have more serious complications [2]. Atlas et al. reported the safe laparoscopic removal of mesh after a failed transvaginal excision but without an associated sacral abscess [3]. We describe the laparoscopic drainage of a sacral abscess and the removal of the associated mesh at the promontory, 8 months after a transvaginal excision of a mesh exposure. © The International Urogynecological Association 2012. AD - Women's Specialty Center, Central Maine Medical Center, Lewiston, ME 04240, United States Department of General and Trauma Surgery, Central Maine Medical Center, Lewiston, ME 04240, United States AU - Roth, T. M. AU - Reight, I. DB - Scopus DO - 10.1007/s00192-011-1630-x IS - 7 KW - Abscess Mesh Sacral colpopexy M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2012 SP - 953-955 ST - Laparoscopic mesh explantation and drainage of sacral abscess remote from transvaginal excision of exposed sacral colpopexy mesh T2 - International Urogynecology Journal TI - Laparoscopic mesh explantation and drainage of sacral abscess remote from transvaginal excision of exposed sacral colpopexy mesh UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84865128362&doi=10.1007%2fs00192-011-1630-x&partnerID=40&md5=4da08dddf35f5a8eb875ffef15bc62bf VL - 23 ID - 1395 ER - TY - JOUR AD - Department of Upper GI and Bariatric Surgery, Royal Derby Hospital, Uttoxeter New Road, Derby, DE22 3NE, United Kingdom AU - Creedon, L. AU - Leeder, P. AU - Awan, A. DB - Scopus DO - 10.1016/j.soard.2013.06.013 IS - 2 M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2014 SP - e19-e21 ST - Laparoscopic adjustable gastric band erosion and migration into the proximal jejunum T2 - Surgery for Obesity and Related Diseases TI - Laparoscopic adjustable gastric band erosion and migration into the proximal jejunum UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84897381286&doi=10.1016%2fj.soard.2013.06.013&partnerID=40&md5=71745390f8658853e7b567243211b4ce VL - 10 ID - 1271 ER - TY - JOUR AB - Gossypibomas are forgatten foreign bodies,iatrogenic.their symptoms are different where they are. they extracted with laparotomy in the past but now we can some article mentioned their extraction was made with laparoscopy. Case 1: 33 Y O female has abdominal pain after c/s for 2.5 years. A gossypiboma was extracted with laparoscopy above umblicus.A superficial surgical site infection existed,drained,subsided. Case 2: 46YO M had a pyleoplasty operation 8 years ago.a gossypiboma was extracted with retroperitonescopy,no postoperative event. Basibuyuk et al reported retroperionescopic extraction of a gossypiboma from single port in first time.Althoug every effort taken the incidence of foreign body detected in the body is about 0.03-0.1%.They are most frequently localized in the intraabdominal cavity followed by tracheobronchial area,pleural cavity,pararenal area,-vagina,spinal chord, neck, femur,breast,bladder,pancreas,and they may cause local irritation,and infection.Tactile sense is absent in laparoscopy. All radiologic examinations(usg ct pet mri etc) be used to detect.we used usg ct.in the end laparoscopy make the diagnosis and remove gossypibomas in our cases with less postoperative pain and cosmosis. Justo et al the computerized tomography (CT) scan is the most useful method for diagnosis; however, sometimes the preoperative diagnosis remains uncertain even after the imaging exam. In that case, laparoscopy arises as a valuable diagnostic tool, as well as a prompt treatment option. Concerning gossypiboma, prevention is preferred rather than treatment. Notwithstanding, there is no highly reliable prevention system. Counting sponges is a method based on staff communication during the surgery with only 77% sensibility. Routine surgical postoperative X-ray (SPOX) constitutes an early detection system, but the need to incorporate a radiopaque marker and to expose the whole surgical field to maximize its efficacy limits its use. More recently, electronic dispositives based on barcode detection and other technological adjuncts for counting sponges are being developed. None of these prevention systems are reliable when used alone. Our education and research clinic was a state hospital before. No surgeon followed above instruction.but now we use all. Multiple procedures and surgical teams, long operations and non-elective operations are the evidenced risk factors.c/s operation was learned full opened of ostium of cervix of the patient. AD - N. Ozlem, General Surgery Department, Ahievran University, KIRSEHIR, Turkey AU - Ozlem, N. DB - Embase DO - 10.1007/s00464-019-07109-x IS - 2 KW - adult bladder breast computer assisted tomography conference abstract education extraction female femoral neck foreign body human incidence laparoscopy pancreas pleura cavity postoperative pain preoperative evaluation prevention pyeloplasty radiodiagnosis risk factor sensibility surgeon touch uterine cervix vagina LA - English M3 - Conference Abstract N1 - L632126299 2020-07-24 PY - 2019 SN - 1432-2218 SP - S741 ST - Laparascopic extraction of an intraperitoneal gossypiboma following C/S and a retroperitoneal gossypiboma following pyeloplasty T2 - Surgical Endoscopy TI - Laparascopic extraction of an intraperitoneal gossypiboma following C/S and a retroperitoneal gossypiboma following pyeloplasty UR - https://www.embase.com/search/results?subaction=viewrecord&id=L632126299&from=export http://dx.doi.org/10.1007/s00464-019-07109-x VL - 33 ID - 326 ER - TY - JOUR AB - The contribution of in vivo biofilm-forming potential of Staphylococcus aureus and Staphylococcus epidermidis was studied in an experimental model of foreign body infections. Increasing inocula (from 102 to 107 organisms) of ica-positive strains of S. aureus and S. epidermidis and their ica-negative isogenic mutants (the ica locus codes for a major polysaccharide component of biofilm) were injected into subcutaneously implanted tissue cages in guinea pigs. Surprisingly, bacterial counts and time-course of tissue cage infection by ica-positive strains of S. aureus or S. epidermidis were equivalent to those of their respective ica-negative mutants, in the locally infected fluids and on tissue-cage-inserted plastic coverslips. © 2003 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved. AD - Division of Infectious Diseases, University Hospitals of Geneva, 1211 Geneva 14, Switzerland Mikrobielle Genetik, Universität Tübingen, 7206 Tübingen, Germany AU - Francois, P. AU - Tu Quoc, P. H. AU - Bisognano, C. AU - Kelley, W. L. AU - Lew, D. P. AU - Schrenzel, J. AU - Cramton, S. E. AU - Götz, F. AU - Vaudaux, P. DB - Scopus DO - 10.1016/S0928-8244(02)00463-7 IS - 2 KW - Biofilm Foreign body infection ica gene Staphylococcus aureus Staphylococcus epidermidis M3 - Article N1 - Cited By :64 Export Date: 10 November 2020 PY - 2003 SP - 135-140 ST - Lack of biofilm contribution to bacterial colonisation in an experimental model of foreign body infection by Staphylococcus aureus and Staphylococcus epidermidis T2 - FEMS Immunology and Medical Microbiology TI - Lack of biofilm contribution to bacterial colonisation in an experimental model of foreign body infection by Staphylococcus aureus and Staphylococcus epidermidis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037456641&doi=10.1016%2fS0928-8244%2802%2900463-7&partnerID=40&md5=b75a97fea9947938b9ccf034b698ea25 VL - 35 ID - 1644 ER - TY - JOUR AB - Foreign body multinucleate giant cells were produced by the implantation of a strip of Melenex in the subcutaneous tissues of mice. The implants were removed at various intervals, and the proportion of multinucleate giant cells as well as the number of nuclei they contained were counted and statistically assessed. The greatest proportion of giant cells were reached 4 wk after implantation, when 25% of the attached cells were multinucleated. The mean nuclear content however was greatest approximately 2 wk after implantation and rapidly fell over the ensuing weeks. The fusion potential, however, remained almost unaltered for the remainder of the experimental period. Transplantation of 7 day implants from normal donors into lethally irradiated recipients demonstrated that the half life of the giant cells is only a few days. Treatment with carrageenin, species specific antisera, actinomycin D and cortisone inhibited, while puromycin enhanced, multinucleate cell formation. Calcium gluconate, EDTA and irradiation had no significant effect. The possible interpretation of some of these findings is discussed. AD - Dept. Pathol., Sch. Med., Univ. West. Australia, Perth, Australia AU - Papadimitriou, J. M. AU - Sforsina, D. AU - Papaelias, L. DB - Scopus IS - 2 M3 - Article N1 - Cited By :54 Export Date: 10 November 2020 PY - 1973 SP - 349-364 ST - Kinetics of multinucleate giant cell formation and their modification by various agents in foreign body reactions T2 - American Journal of Pathology TI - Kinetics of multinucleate giant cell formation and their modification by various agents in foreign body reactions UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015890928&partnerID=40&md5=49523004d85b07fea66de3011bd8d749 VL - 73 ID - 1780 ER - TY - JOUR AB - Ketorolac 0.45 ophthalmic solution is a topical NSAID indicated in the US for the treatment of ocular pain and inflammation following cataract surgery.In animal studies, the ocular relative bioavailability of single-dose topical ketorolac 0.45 ophthalmic solution was 2- to 3-fold higher than that of ketorolac 0.4 ophthalmic solution.In two identically designed, randomized, double-masked, multicentre trials in adult patients undergoing cataract extraction, the proportions of patients with a summed ocular inflammation score of zero for anterior chamber cell count plus anterior chamber flare on day 14 after surgery were significantly greater in those treated with topical ketorolac 0.45 ophthalmic solution than in those treated with vehicle placebo.Compared with placebo, topical ketorolac 0.45 ophthalmic solution significantly increased the proportion of patients who were pain-free on the day after surgery in both trials.Ketorolac 0.45 ophthalmic solution was generally well tolerated in clinical trials with lower overall incidences of treatment-emergent and treatment-related adverse events than placebo, and with no single treatment-related adverse event having a higher incidence than with placebo. © 2011 Adis Data Information BV. All rights reserved. AD - P.L. McCormack, Adis A Wolters Kluwer Business, 41 Centorian Drive, North Shore 0754, Auckland, New Zealand AU - McCormack, P. L. C1 - acuvail DB - Embase Medline DO - 10.2165/11207450-000000000-00000 IS - 7 KW - ketorolac trometamol amfenac bromfenac cyclooxygenase 1 cyclooxygenase 2 gatifloxacin ketorolac nepafenac paracetamol placebo unclassified drug analgesic activity anterior eye chamber cell anterior eye chamber disease anterior eye chamber flare anterior eye chamber inflammation antiinflammatory activity antipyretic activity area under the curve article blurred vision cataract extraction conjunctival hemorrhage conjunctival hyperemia cornea edema drug bioavailability drug blood level drug efficacy drug induced headache drug penetration drug tolerability enzyme inhibition epiphora eye burning eye inflammation eye pain eyelid edema face pain foreign body human intraocular pressure iritis maximum plasma concentration nonhuman phacoemulsification photophobia postoperative pain priority journal Leporidae recommended drug dose side effect single drug dose time to maximum plasma concentration uveitis visual acuity wound healing acuvail LA - English M3 - Article N1 - L362074452 2011-07-13 2011-07-18 PY - 2011 SN - 1170-229X 1179-1969 SP - 583-589 ST - Ketorolac 0.45% ophthalmic solution T2 - Drugs and Aging TI - Ketorolac 0.45% ophthalmic solution UR - https://www.embase.com/search/results?subaction=viewrecord&id=L362074452&from=export http://dx.doi.org/10.2165/11207450-000000000-00000 VL - 28 ID - 537 ER - TY - JOUR AU - Seeger, D. DB - Scopus IS - 6 M3 - Article N1 - Export Date: 10 November 2020 PY - 2017 SP - 18-21 ST - Keeping count: With the Surgicount Safety-Sponge System, Stryker aims to help healthcare facilities put an end to retained surgical sponges T2 - Surgical Products TI - Keeping count: With the Surgicount Safety-Sponge System, Stryker aims to help healthcare facilities put an end to retained surgical sponges UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85029179970&partnerID=40&md5=c1767cba78f271eca982df7cbb946198 VL - 36 ID - 1124 ER - TY - JOUR AB - Learning Objective #1: Outline the differential diagnosis of an intracardiac mass in renal cell carcinoma Learning Objective #2: Discuss differentiation and management of bland versus tumor thrombi CASE: A 66 year old man with stage IV renal cell carcinoma (RCC), a non-occlusive IVC tumor thrombus and end-stage renal disease on he-modialysis via a right internal jugular permacath was admitted with a 5-day history of fever and weakness. He had a temperature of 99.3, a WBC count of 17.2 and was found to have Klebsiella bacteremia. Physical exam revealed a new systolic murmur, which prompted echocardiogram, showing a large, mobile, multi-lobed structure in the right atrium likely attached to the permacath, suggestive of thrombus (could not rule out vegetation). Antibiotics and heparin were started. CT showed a chronic IVC tumor thrombus that did not extend into the SVC or right atrium, suggesting the right atrial mass was not tumor thrombus. Permacath was removed and to definitively rule out embolization of the right atrial thrombus, CTPE was performed, revealing a right lower lobe pulmonary embolism and warfarin was initiated. IMPACT/DISCUSSION: RCC is a highly vascular tumor that can invade through the renal vein and into the IVC, with 10-15% of cases resulting in tumor thrombus formation. Less commonly (1%), the tumor may extend into the right cardiac chamber. Accurate differentiation of bland from tumor thrombus is crucial for proper management. While both bland and tumor thrombi present as vessel filling defects, a malignant thrombus has continuity with the primary tumor, enhancement and vessel expansion on CT or MRI. Because a bland thrombus Results from IVC compression by a renal mass, it presents as vessel narrowing on imaging. While nephrectomy and thrombectomy treat tumor thrombi, anticoagulation is used for bland thrombi. Though tumor thrombus dis-lodgement is a known complication of thrombectomy, the development of tumor emboli outside the lung in the absence of such manipulation is unclear. The differential diagnosis of an intracardiac mass in a septic RCC patient can span different etiologies including infectious (vegetation), malignant (primary tumor, metastases, tumor thrombus) and hematologic (bland thrombus). As imaging was strongly suggestive of a thrombus, several key details pointed to bland over tumor thrombus. Risk factors for thrombosis, including a hypercoagulable state due to malignancy as well as foreign body effect from the IVC tumor thrombus and permacath, and attachment of the mass to the permcath raised our suspicion for a bland thrombus. Moreover, lack of IVC thrombus extension into the SVC and right atrium suggested the mass was more likely bland thrombus. Thus, anticoagulation and antibiotics were given empirically. Conclusion: This case demonstrates the importance of reviewing all clinical data when narrowing the differential diagnosis for an intracardiac mass. Moreover, identification of thrombi in RCC patients warrants subsequent differentiation of bland from tumor thrombus for effective management. AD - K.G. Patel, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, United States AU - Patel, K. G. AU - Yin, D. AU - Schlair, S. DB - Embase DO - 10.1007/11606.1525-1497 IS - 2 KW - antibiotic agent heparin warfarin aged anticoagulation bacteremia blood clotting body weight cancer patient cancer staging cancer surgery case report clinical article complication compression conference abstract dialysis catheter differential diagnosis differentiation drug therapy echocardiography end stage renal disease fever foreign body heart right atrium human hypercoagulability kidney vein Klebsiella learning leukocyte count lung agenesis lung embolism male nephrectomy nonhuman nuclear magnetic resonance imaging physical examination primary tumor renal cell carcinoma risk factor surgery systolic heart murmur thrombectomy tumor thrombus vascular tumor vegetation weakness LA - English M3 - Conference Abstract N1 - L629001018 2019-08-27 PY - 2019 SN - 1525-1497 SP - S570 ST - Keep your eye on thrombi in renal cell carcinoma patients T2 - Journal of General Internal Medicine TI - Keep your eye on thrombi in renal cell carcinoma patients UR - https://www.embase.com/search/results?subaction=viewrecord&id=L629001018&from=export http://dx.doi.org/10.1007/11606.1525-1497 VL - 34 ID - 316 ER - TY - JOUR AB - Animal models of Staphylococcus aureus infective endocarditis (IE), especially in rodents, are commonly used to investigate the underlying pathogenesis, disease progression, potential diagnostic approaches, and therapeutic treatment. All these models are based on surgical interventions, and imply valve trauma by placing a polyurethane catheter at the aortic root. While the influence of endothelial damage and inflammation on the induction of IE has been studied intensively, the role of the catheter, as permanent source of bacteremia, and the interplay with bacterial virulence factors during the formation of IE is poorly understood. In our study, we aimed at identifying which set of preconditions is required for induction and formation of IE: (1) tissue injury, (2) permanent presence of bacteria, and (3) presence of the full bacterial repertoire of adhesion proteins. We investigated the manifestation of the disease in different modifications of the animal model, considering different degrees of endothelial damage and the presence or absence of the catheter. In four infection models the induction of IE was assessed by using two bacterial strains with different expression patterns of virulence factors - S. aureus 6850 and Newman. In vivo magnetic resonance imaging showed conspicuous morphological structures on the aortic valves, when an endothelial damage and a continuous bacterial source were present simultaneously. Cellular and inflammatory pathophysiology were characterized additionally by histology, real-time quantitative polymerase chain reaction analysis, and bacterial counts, revealing strain-specific pathogenesis and manifestation of IE, crucially influenced by bacterial adherence and toxicity. The severity of IE was dependent on the degree of endothelial irritation. However, even severe endothelial damage in the absence of a permanent bacterial source resulted in reduced valve infection. The spread of bacteria to other organs was also dependent on the pathogenic profile of the infectious agent. AD - Translational Research Imaging Center, Department of Clinical Radiology, University Hospital Muenster, Muenster, Germany. Institute of Medical Microbiology, University Hospital Jena, Jena, Germany. Institute of Musculoskeletal Medicine, University Hospital Muenster, Muenster, Germany. Institute of Medical Microbiology, University Hospital Muenster, Muenster, Germany. European Institute for Molecular Imaging, University of Muenster, Muenster, Germany. Institute for Neuropathology, University Hospital Muenster, Muenster, Germany. Klinik und Poliklinik für Radiologie, Klinikum der Universität München, Munich, Germany. AN - 32625192 AU - Schwarz, C. AU - Hoerr, V. AU - Töre, Y. AU - Hösker, V. AU - Hansen, U. AU - Van de Vyver, H. AU - Niemann, S. AU - Kuhlmann, M. T. AU - Jeibmann, A. AU - Wildgruber, M. AU - Faber, C. C2 - PMC7314968 DO - 10.3389/fmicb.2020.01325 DP - NLM ET - 2020/07/07 KW - Mri Staphylococcus aureus endocarditis foreign body mouse model LA - eng N1 - 1664-302x Schwarz, Christian Hoerr, Verena Töre, Yasemin Hösker, Vanessa Hansen, Uwe Van de Vyver, Hélène Niemann, Silke Kuhlmann, Michael T Jeibmann, Astrid Wildgruber, Moritz Faber, Cornelius Journal Article Front Microbiol. 2020 Jun 18;11:1325. doi: 10.3389/fmicb.2020.01325. eCollection 2020. PY - 2020 SN - 1664-302X (Print) 1664-302x SP - 1325 ST - Isolating Crucial Steps in Induction of Infective Endocarditis With Preclinical Modeling of Host Pathogen Interaction T2 - Front Microbiol TI - Isolating Crucial Steps in Induction of Infective Endocarditis With Preclinical Modeling of Host Pathogen Interaction VL - 11 ID - 254 ER - TY - JOUR AB - Primary amyloidosis of the larynx is a rare benign disease of unknown aetiology. Isolated epiglottic involvement with amyloidosis is an extremely uncommon benign laryngeal pathology and can present with a foreign body sensation in the throat. This lesion should be kept in mind in cases with a long-standing foreign body sensation in the throat. Observation and endoscopic carbon dioxide laser excision are the main methods of treatment. Long-term follow-up is also required because of the slow progressive nature of this disease. © 2015 The Authors. Production and hosting by Elsevier Ltd on behalf of Taibah University. AD - Department of ENT, IMS and SUM Hospital, Kalinga Nagar, Bhubaneswar-3, Odisha, India Central Research Laboratory, IMS and SUM Hospital, Siksha O Anusandhan University, K8, Kalinganagar, Bhubaneswar, Odisha, India AU - Swain, S. K. AU - Sahu, M. C. DB - Scopus DO - 10.1016/j.jtumed.2015.07.004 IS - 4 KW - Amyloidosis Epiglottis Foreign body sensation in throat M3 - Article N1 - Export Date: 10 November 2020 PY - 2015 SP - 488-491 ST - Isolated primary amyloidosis of the epiglottis presenting as a long-standing foreign body sensation in throat: A case report T2 - Journal of Taibah University Medical Sciences TI - Isolated primary amyloidosis of the epiglottis presenting as a long-standing foreign body sensation in throat: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960882868&doi=10.1016%2fj.jtumed.2015.07.004&partnerID=40&md5=cc4e1ba8c030a686ce42ff661e30b780 VL - 10 ID - 1238 ER - TY - JOUR AB - The etiology of granulomatous appendicitis includes infectious diseases, foreign bodies and diseases of unknown etiology such as Crohn's disease and sarcoidosis. Pain in the right lower guardant is a common symptom of intestinal Crohn's disease but, pain in this area can also be the presenting symptom of acute appendicitis. Crohn's disease affects any part of the gastrointestinal tract including the vermiform appendix. Crohn's disease initially confined to the appendix is rare and there are less than 100 well-documented cases in the literature. A 28-years-old female patient was admitted to our hospital because of fever up to 39°C and abdominal pain in hte right lower quadrant with bloating. Serology and faecal, urine and blood cultures for microbial infection including Yersinia proved negaive. Lower abdomen ultrasonography revealed no evidence of adnexae inflammation but suspected thickness of the bowel wall in the right lower quadrant. Because of no response to conservative treatment two months later surgery was performed. At laparotomy a long, thickened and distended appendix was found and removed. No other lesions were noted in the intestines or mesentery. Histological examination of the removed appendix showed signs compatible with Crohn's disease of the appendix. In case of Crohn's disease of the appendix two clinical possibilities may arise; the first is the presence of mild Crohn's disease in other intestinal parts and the second possibility is the risk of relapse which occured in 7-14% of the published cases. Could this case be regarded as an isolated Crohn's disease of the appendix or as a granulomatous and follicular appendicitis of unknown etiology (idiopathic) and unrelated to a "formal" Crohn's disease according to the accepted definition. AD - Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece Department of Medicine-Gastroenterology, Medical School, University of Ioannina, Ioannina, Greece AU - Tsianos, E. AU - Katsanos, K. AU - Mpaltayiannis, G. AU - Christodoulou, D. DB - Scopus IS - 2 KW - Appenditis Appendix Crohn's disease Granuloma M3 - Article N1 - Export Date: 10 November 2020 PY - 2001 SP - 132-134 ST - Isolated Crohn's disease of the vermiform appendix or chronic granulomatous appendicis? T2 - Annals of Gastroenterology TI - Isolated Crohn's disease of the vermiform appendix or chronic granulomatous appendicis? UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-34548356599&partnerID=40&md5=2dc868843794f66fda8c51d2d7cbd9d7 VL - 14 ID - 1666 ER - TY - JOUR AB - Abuse of an otherwise properly installed and maintained operating room system may result in rendering the environment unsatisfactory for critical types of surgery, especially when a patient's resistance is lowered by disease or drugs, or when a large foreign body is implanted. No type of special air-handling system will correct these abuses even though it may reduce ambient bioparticle counts. From all available valid evidence, the conclusion is drawn that laminar flow is less effective against wound infection than adherence to proper techniques and correction of abuses of the operating room environment by the surgical team and support personnel. AN - 1012101 AU - Laufman, H. DA - Nov-Dec DP - NLM ET - 1976/11/01 IS - 6 KW - *Air Microbiology Environment Humans *Operating Rooms Surgical Wound Infection/*prevention & control *Ventilation LA - eng N1 - Laufman, H Journal Article United States Med Instrum. 1976 Nov-Dec;10(6):269-74. PY - 1976 SN - 0090-6689 (Print) 0090-6689 SP - 269-74 ST - Is laminar airflow necessary for prophylaxis against wound infection? T2 - Med Instrum TI - Is laminar airflow necessary for prophylaxis against wound infection? VL - 10 ID - 4 ER - TY - JOUR AB - To compare the biological responses following an endoluminal repair and a conventional open repair of abdominal aortic aneurysm (AAA), 14 patients who underwent an endoluminal repair (endograft group) and 26 who underwent an open repair (open group) were investigated. As markers of biological responses, interleukin-6 (IL-6) and -8 (IL-8), granulocyte elastase (GEL), white blood cell count (WBC), and serum C-reactive protein (CRP) were all measured preoperatively as well as on postoperative days (POD) 1, 3, and 6. In addition, the blood loss, duration of surgery, initial oral intake the day after surgery, and length of hospital stay were compared between both groups. The plasma levels of IL-6, GEL, CRP, and WBC were higher in the endograft group than in the open group, while the CRP, WBC, and GEL levels all peaked on POD 3. The plasma level of IL-6 remained high in the endograft group, compared with that in the open group throughout the study period. Conversely, blood loss, initial oral intake the day after surgery, and the length of hospital stay were all significantly greater in the open group than in the endograft group, although there was no significant difference in the duration of surgery between the two groups. These findings indicate that although the endoluminal repair of AAA is supposed to be less invasive, the biological responses tend to be greater because of the manipulation related to the insertion of the stent graft. AD - First Department of Surgery, Yamaguchi University School of Medicine, Yamaguchi 755-8505, Japan AU - Morikage, N. AU - Esato, K. AU - Zenpo, N. AU - Fujioka, K. AU - Takenaka, H. DB - Scopus DO - 10.1007/PL00010062 IS - 2 KW - Abdominal aortic aneurysm Biological response Conventional open repair Endoluminal repair Stent graft M3 - Article N1 - Cited By :39 Export Date: 10 November 2020 PY - 2000 SP - 142-146 ST - Is endovascular treatment of abdominal aortic aneurysms less invasive regarding the biological responses? T2 - Surgery Today TI - Is endovascular treatment of abdominal aortic aneurysms less invasive regarding the biological responses? UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034089393&doi=10.1007%2fPL00010062&partnerID=40&md5=3f115d2d11320b20aae9eb663fc66b87 VL - 30 ID - 1683 ER - TY - JOUR AB - The diagnosis of irritable bowel syndrome (IBS) frequently is made after the exclusion of a mechanical etiology for a patient's symptoms. This case demonstrates that IBS symptoms can be caused by a rare complication of a common surgery: mesh herniorrhaphy repair. The patient is a 50-year-old woman who underwent periumbilical Marlex mesh herniorrhaphy 13 years before presentation. After her operation, the patient developed constipation (approximately one bowel movement per week) alternating with diarrhea for approximately 10 years. An abdominal radiograph showed large amounts of stool, and after a normal colonoscopy the patient was diagnosed with IBS. The patient was treated with tegaserod (Zelnorm) and polyethylene glycol (MiraLAX), which did not palliate her symptoms. The patient presented with obstructive symptoms and physical findings of an incarcerated umbilical hernia. A computed tomography (CT) scan of the abdomen confirmed an umbilical hernia involving a segment of small bowel with surrounding fecalization of enteric contents. During operative repair, the patient was found to have Marlex mesh fully eroded into the lumen of the small bowel, causing a partial obstruction. The involved section of small bowel was resected, and during serial follow-up the patient had complete resolution of her IBS-like symptoms. A discussion follows regarding the implications of mesh migration, and questions are posed for future research. AD - Medical Corps, United States Air Force, Dewitt Army Hospital, Fort Belvoir, VA, United States AU - Barnes, M. G. DB - Scopus DO - 10.3122/jabfm.2012.01.100190 IS - 1 KW - Case report Hernioplasty Herniorrhaphy Irritable bowel syndrome Polypropylene Surgical mesh M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2012 SP - 120-123 ST - Irritable bowel syndrome: A "mesh" of a situation T2 - Journal of the American Board of Family Medicine TI - Irritable bowel syndrome: A "mesh" of a situation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84855675813&doi=10.3122%2fjabfm.2012.01.100190&partnerID=40&md5=9288be5a1cdeab44c926b46a66577d4b VL - 25 ID - 1393 ER - TY - JOUR AB - INTRODUCTION AND OBJECTIVE: Root Cause Analysis (RCA) is a well-known and effective method of analyzing errors made in the healthcare setting. We aimed to categorize events leading to RCA in urology ORs at VA medical centers in order to increase understanding of when RCA may be appropriate and if where changes may be implemented as a result. METHODS: A dataset of surgery RCAs at VA medical centers that were submitted between the start of fiscal year 2015 to present was created using terms including urology, -gic, -gist, vasectomy; prostatectomy (including TURP, RRP, LRP, PVP), nephrectomy, cystectomy, cystoscopy, lithotripsy, kidney stone, ureteroscopy, ureter, -al, urethral, TURBT, bladder/prostate cancer, and gleason. Cases that did not pertain to an event in a urology OR were excluded. The cases were then categorized based on the type of event. RESULTS: A total of 62 cases were identified. The most common pattern identified was equipment or instrument issue with 23 cases. For example, 'no sterile flexible ureteroscopes available for scheduled ureteroscopy identified after patient asleep'; 'smoking light cord'. There were 12 events categorized as retained foreign bodies (surgical sponge, retained guidewire), 8 pertaining to medical or anesthesia event (incorrect dosing, STEMI during TURP), and 7 pertaining to pathology errors (missing specimen, incorrect diagnosis later revised, mislabeled specimen). There were 6 wrong site surgeries (wrong side ureteral stent placement, prostate biopsy performed in patient scheduled for cystoscopy), 5 cases with incorrect patient information or consent (TURBT performed without consent), and 4 cases identified as major surgical complications (renal artery injury during ureteroscopy, unrecognized bladder perforation during TURP). In 2 cases the wrong case was performed or there was inappropriate work up. One case caused a significant delay in treatment, one case pertained to an incorrect count, and one case identified lack of appropriate credentialing. CONCLUSIONS: RCA is an important tool in improving quality and safety of care. We identified several patterns of events leading to RCA pertaining to urologic operating rooms. By categorizing theses variables, we can better identify targets for efforts on improving quality and safety in our operating rooms. (Figure Presented). AD - L.M. Peard, Lexington, KY, United States AU - Peard, L. M. AU - Gunnar, W. AU - Mills, P. AU - Harris, A. M. DB - Embase KW - accreditation adult anesthesia bladder cancer bladder perforation cancer patient cancer surgery complication conference abstract cystectomy cystoscopy flexible ureteroscope foreign body guide wire human kidney artery lithotripsy major clinical study male nephrectomy nephrolithiasis operating room patient information peroperative complication prostate biopsy prostate cancer prostatectomy root cause analysis smoking ST segment elevation myocardial infarction surgery surgical sponge ureter stent ureteroscopy urology vasectomy veteran LA - English M3 - Conference Abstract N1 - L632060227 2020-07-27 PY - 2020 SN - 1527-3792 SP - e991-e992 ST - Investigation of urology intraoperative events leading to root cause analysis at national veterans affairs medical centers T2 - Journal of Urology TI - Investigation of urology intraoperative events leading to root cause analysis at national veterans affairs medical centers UR - https://www.embase.com/search/results?subaction=viewrecord&id=L632060227&from=export VL - 203 ID - 278 ER - TY - JOUR AB - An increasing number of reports suggest that Propionibacterium acnes can cause serious invasive infections. Currently, only limited data exist regarding the spectrum of invasive P. acnes infections. We conducted a non-selective cohort study at a tertiary hospital in the UK over a 9-year-period (2003–2012) investigating clinical manifestations, risk factors, management, and outcome of invasive P. acnes infections. Forty-nine cases were identified; the majority were neurosurgical infections and orthopaedic infections (n = 28 and n = 15 respectively). Only 2 cases had no predisposing factors; all neurosurgical and 93.3 % of orthopaedic cases had a history of previous surgery and/or trauma. Foreign material was in situ at the infection site in 59.3 % and 80.0 % of neurosurgical and orthopaedic cases respectively. All neurosurgical and orthopaedic cases required one or more surgical interventions to treat P. acnes infection, with or without concomitant antibiotic therapy; the duration of antibiotic therapy was significantly longer in the group of orthopaedic cases (median 53 vs 19 days; p = 0.0025). All tested P. acnes isolates were susceptible to penicillin, ampicillin and chloramphenicol; only 1 was clindamycin-resistant. Neurosurgical and orthopaedic infections account for the majority of invasive P. acnes infections. Most cases have predisposing factors, including previous surgery and/or trauma; spontaneous infections are rare. Foreign material is commonly present at the site of infection, indicating that the pathogenesis of invasive P. acnes infections likely involves biofilm formation. Since invasive P. acnes infections are associated with considerable morbidity, further studies are needed to establish effective prevention and optimal treatment strategies. © 2014, Springer-Verlag Berlin Heidelberg. AD - Academic Unit of Clinical & Experimental Sciences, University of Southampton, Southampton, United Kingdom Department of Paediatric Immunology & Infectious Diseases, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom Institute for Life Sciences, University of Southampton, Southampton, United Kingdom Southampton NIHR Respiratory Biomedical Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom Department of Paediatrics, The University of Melbourne, Parkville, Australia Southampton National Institute for Health Research Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom Centre for Biological Sciences, University of Southampton, Southampton, United Kingdom Department of Microbiology, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom Public Health England South East Regional Laboratory, Southampton, United Kingdom NIHR Wellcome Trust Clinical Research Facility, Mailpoint 218, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, SO16 6YD, United Kingdom AU - Tebruegge, M. AU - Jones, C. AU - de Graaf, H. AU - Sukhtankar, P. AU - Allan, R. N. AU - Howlin, R. P. AU - Browning, D. AU - Schuster, H. AU - Pallett, A. AU - Patel, S. AU - Faust, S. N. DB - Scopus DO - 10.1007/s10096-014-2256-y IS - 3 M3 - Article N1 - Cited By :9 Export Date: 10 November 2020 PY - 2015 SP - 527-534 ST - Invasive Propionibacterium acnes infections in a non-selective patient cohort: clinical manifestations, management and outcome T2 - European Journal of Clinical Microbiology and Infectious Diseases TI - Invasive Propionibacterium acnes infections in a non-selective patient cohort: clinical manifestations, management and outcome UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84941734204&doi=10.1007%2fs10096-014-2256-y&partnerID=40&md5=98c596e56536ed3a4dd2e47b0f7ee5e9 VL - 34 ID - 1229 ER - TY - JOUR AB - Intrauterine contraceptive device (IUCD) is relatively safe but still with some serious risks. Uterus perforation is rare and would be fatal. A case of Cu-7 IUCD invading into the sigmoid colon through uterine perforation caused by a pelvic blunt trauma was presented. Our case showed that uterus perforation by an IUCD could induce utero-sigmoid fistula which is likely to be missed. Imaging is required when the patients with IUCD present abdominal pain, particularly with a history of trauma. © 2015 Production and hosting by Elsevier B.V. on behalf of Daping Hospital and the Research Institute of Surgery of the Third Military Medical University. AD - Trauma Research Center, Kashan University of Medical Sciences, Kashan, Iran AU - Davoodabadi, A. AU - Mohammadzadeh, M. AU - Amirbeigi, M. AU - Jazayeri, H. DB - Scopus DO - 10.1016/j.cjtee.2015.09.006 IS - 4 KW - Colon Intrauterine devices Sigmoid Uterine perforation M3 - Article N1 - Export Date: 10 November 2020 PY - 2015 SP - 235-237 ST - Invading of intrauterine contraceptive device into the sigmoid colon through uterine perforation caused by a blunt trauma T2 - Chinese Journal of Traumatology - English Edition TI - Invading of intrauterine contraceptive device into the sigmoid colon through uterine perforation caused by a blunt trauma UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84955305028&doi=10.1016%2fj.cjtee.2015.09.006&partnerID=40&md5=1addcffeec474aad0e3ea34b12a925ab VL - 18 ID - 1222 ER - TY - JOUR AB - Pediatric neurosurgeons commonly instill vancomycin into the ventricles to treat shunt infections. This use for vancomycin, however, has not been studied in the laboratory to evaluate possible toxicities and side effects. We report two cases of cerebrospinal fluid eosinophilia (CSFE) secondary to the intraventricular administration of vancomycin. Two other cases of shunt infection during the same time period were treated for only 2 days with intraventricular vancomycin and did not manifest CSFE. We address the clinical problems and possible detrimental effects of CSFE in the setting of shunt infection. We propose a mechanism of vancomycin-induced mast cell degranulation and subsequent release of eosinophil chemotactic factor as a cause of CSFE. An initial dose of intraventricular vancomycin should take into account volume of distribution (ventricular size) to obtain a peak cerebrospinal fluid concentration of 20 to 30 μg/mL. We recommend following daily cell counts and vancomycin peak and trough levels to calculate the amount and frequency of intraventricular vancomycin required to maintain safe and effective concentrations and to monitor for CSFE. © by the Congress of Neurological Surgeons. AD - Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States AU - Grabb, P. A. AU - Albright, A. L. DB - Scopus DO - 10.1227/00006123-199204000-00029 IS - 4 KW - Cerebrospinal fluid Eosinophilia Intraventricular antibiotics Vancomycin M3 - Article N1 - Cited By :36 Export Date: 10 November 2020 PY - 1992 SP - 630-635 ST - Intraventricular vancomycin-induced cerebrospinal fluid eosinophila: Report of two patients T2 - Neurosurgery TI - Intraventricular vancomycin-induced cerebrospinal fluid eosinophila: Report of two patients UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026637969&doi=10.1227%2f00006123-199204000-00029&partnerID=40&md5=96c766b0c611cbbe556d8e19202e6f20 VL - 30 ID - 1735 ER - TY - JOUR AB - BACKGROUND During any surgical procedure, there are several factors that may lead to morbidity and mortality. One of those factors is a retained cotton or gauze surgical sponge inadvertently left in the body during an operation, known as gossypiboma. This clinical oversight may cause serious postoperative complications and increase the risk of mortality, particularly if left undiscovered. Furthermore, this issue adds to the economic burden on healthcare systems by increasing the rate of reoperation and rehospitalization. The length of postoperative gossypiboma diagnosis varies greatly, as patients may either present acutely with symptoms such as a palpable mass, pain, nausea, and vomiting, or remain asymptomatic for several years. CASE REPORT We report the case of a 48-year-old man who underwent a thoracotomy after a road traffic accident. The resulting empyema led to the intraoperative discovery of an intrathoracic gossypiboma, which was initially interpreted radiologically as a part of the previous surgical staple line. The causative agent was discovered by the team's nurses during the postsurgical count of instruments and sponges, and who were alerted to a recovered sponge differing in appearance from the sponges used for that procedure. CONCLUSIONS In general, proper counting and adherence to the World Health Organization 'Surgical Safety Checklist' can greatly improve the outcome of any surgery. The diagnosis of gossypiboma is often late or missed entirely and leads to additional interventions that can be avoided or detected early when the material contains a radiopaque marker. In cases under suspicion of any mistakenly left object, the use of intraoperative radiology before skin closure is highly recommended to prevent postoperative complications for the patient and organization. AD - Thoracic Surgery Division, Department of Surgery, King Fahad Hospital of The University, College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia. AN - 32893262 AU - Othman, S. A. AU - AlSafwani, J. Q. AU - AlSahwan, A. AU - Aljehani, Y. C2 - PMC7491945 DA - Sep 7 DO - 10.12659/ajcr.923992 DP - NLM ET - 2020/09/08 LA - eng N1 - 1941-5923 Othman, Sharifah A AlSafwani, Jihad Q AlSahwan, Abdullah Aljehani, Yasser Journal Article Am J Case Rep. 2020 Sep 7;21:e923992. doi: 10.12659/AJCR.923992. PY - 2020 SN - 1941-5923 SP - e923992 ST - Intrathoracic Gossypiboma: An Overlooked Entity T2 - Am J Case Rep TI - Intrathoracic Gossypiboma: An Overlooked Entity VL - 21 ID - 260 ER - TY - JOUR AB - Gossypiboma refers to retained sponge or swab in any body cavity after surgery. Although it is a rare occurence, it can lead to various complications which include adhesions, abscess formation and subsequent infections. Gossypiboma occurs as a result of not using radio-opaque sponges, poorly performed sponge counts, inadequate wound explorations on suspicion and misread intraoperative radiographs. Therefore, this event can be avoided if strict preventive measures are taken. Moreover, further complications can be avoided following the correct and early diagnosis of gossypiboma. Gossypiboma is an important topic as it carries great medicolegal consequences for the surgeon. We have presented three cases of intrathoracic gossipiboma following previous cardiothoracic surgeries. They presented years after their surgeries, with features varying from patient to patient, ranging from cough and fever to no sypmtoms at all. CT scan only showed a mass lesion in all cases, therefore we proceeded for CT-guided biopsy which was also found to be inconclusive. It was only after entering the thoracic cavity via video-assisted thoracoscopy/thoracotomy that the diagnosis was made and sponges were taken out successfully. All our cases recovered with no further complications. AD - Department of Cardiothoracic Surgery, Aga Khan University Hospital, Karachi, Pakistan. AN - 24403384 AU - Hameed, A. AU - Naeem, A. AU - Azhar, M. AU - Fatimi, S. H. C2 - PMC3902495 DA - Jan 8 DO - 10.1136/bcr-2013-201814 DP - NLM ET - 2014/01/10 KW - Aged *Coronary Artery Bypass Diagnosis, Differential Foreign Bodies/*diagnosis/surgery *Heart Valve Prosthesis Implantation Humans *Lung Male *Mediastinum Middle Aged Mitral Valve Insufficiency/surgery Postoperative Complications/*diagnosis/surgery Reoperation *Surgical Sponges Thoracic Surgery, Video-Assisted Tomography, X-Ray Computed LA - eng N1 - 1757-790x Hameed, Aamir Naeem, Ayesha Azhar, Maimoona Fatimi, Saulat Husnain Case Reports Journal Article BMJ Case Rep. 2014 Jan 8;2014:bcr2013201814. doi: 10.1136/bcr-2013-201814. PY - 2014 SN - 1757-790x ST - Intrathoracic gossypiboma T2 - BMJ Case Rep TI - Intrathoracic gossypiboma VL - 2014 ID - 147 ER - TY - JOUR AB - Intraperitoneal forgotten foreign bodies are prone to create adhesions and to encapsulate, or to provoke an exudative response, with or without accompanying bacterial infection. Often a process of self-extrusion is initiated. This is also true for gossypibomas, retained surgical sponges. Presentation is possible as a pseudotumoral, occlusive, or septic syndrome; several cases, however, have remained asymptomatic for as long as several decades. Ultrasonography and radiology (especially computed tomography) contribute significantly to the detection of gossypibomas; magnetic resonance imaging is a less used technique. Detection by plain radiography is difficult. Ultrasonography demonstrates a hyperreflective mass with hypoechoic rim and a strong posterior shadow. Computed tomography shows a well defined mass with internal heterogeneous densities. Therapy consists of operative removal of the foreign body in association with resolving its complications. Adding a series of five cases to the existing literature reports, the fate of intraperitoneal forgotten surgical sponges is reviewed. AD - Department of Surgery, University Hospital of Antwerp, Belgium. AN - 10787070 AU - Lauwers, P. R. AU - Van Hee, R. H. DA - May DO - 10.1007/s002689910084 DP - NLM ET - 2000/04/29 IS - 5 KW - Adult Female *Foreign Bodies Humans Male Middle Aged *Peritoneum Postoperative Complications/*etiology *Surgical Sponges LA - eng N1 - Lauwers, P R Van Hee, R H Case Reports Journal Article Review United States World J Surg. 2000 May;24(5):521-7. doi: 10.1007/s002689910084. PY - 2000 SN - 0364-2313 (Print) 0364-2313 SP - 521-7 ST - Intraperitoneal gossypibomas: the need to count sponges T2 - World J Surg TI - Intraperitoneal gossypibomas: the need to count sponges VL - 24 ID - 31 ER - TY - JOUR AB - Endoscopic biliary stenting is a well-recognised method of palliation of malignant biliary obstruction. Distal stent migration causing duodenal perforation is an uncommon complication of this procedure and is usually delayed. Early stent migration resulting in duodenal perforation is extremely rare and can be easily overlooked. We present a case of stent migration and resultant intraperitoneal duodenal perforation that occurred 24 hours following plastic stent insertion for a malignant biliary stricture in a 63-year-old woman. The patient required emergent abdominal laparoscopy with the placement of intraperitoneal drain, followed by endoscopic extraction of the stent and closure of the defect using a through-the-scope clip. This case report addresses intraperitoneal duodenal perforation secondary to early migration of biliary stents. Special emphasis is placed on the importance of prompt diagnosis and the use of endoclips in the management of this serious complication of endoprosthesis. © BMJ Publishing Group Limited 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. AD - Department of Internal Medicine, King Abdullah University Hospital, Jordan University of Science and Technology, Irbid, Jordan Department of General Surgery and Urology, King Abdullah University Hospital, Jordan University of Science and Technology, Irbid, Jordan AU - Jadallah, K. AU - Alzubi, B. AU - Sweidan, A. AU - Almanasra, A. R. C7 - e230324 DB - Scopus DO - 10.1136/bcr-2019-230324 IS - 9 KW - Biliary Intervention Endoscopy Gastrointestinal Surgery M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2019 ST - Intraperitoneal duodenal perforation secondary to early migration of biliary stent: Closure with through-the-scope clip T2 - BMJ Case Reports TI - Intraperitoneal duodenal perforation secondary to early migration of biliary stent: Closure with through-the-scope clip UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071763202&doi=10.1136%2fbcr-2019-230324&partnerID=40&md5=60c0d83f3c78c74a861e450aaf6a4eec VL - 12 ID - 999 ER - TY - JOUR AB - INTRODUCTION: Gossypiboma is a retained surgical sponge inside our body after surgical intervention. It is most commonly found in abdominal cavity. Its occurrence in thoracic cavity as intrapericardial gossypiboma is extremely rare. PRESENTATION OF CASE: We present a 25 year old male with complaint of chest pain for 1 year. He had a history of total correction of Tetralogy of fallot 14 years back, at another hospital. On clinical examination and investigations including contrast enhanced computed tomography (CECT) of thorax; diagnosis of right anterior mediastinal mass of germ cell tumor was made and planned for thoracotomy. On exploration, the gauze piece of 31 cm was removed from the pericardial mass and a final diagnosis of gossypiboma was made. DISCUSSION: Although gossypibomas are commonly reported in abdominal and pelvic surgery but a prolonged operative time, untrained staff, poor communication in sponge count may favour the occurrence in thoracic cavity. A patient with intrathoracic gossypiboma usually presents with chest pain, dyspnoea, thoracic mass or fever. CECT and Magnetic resonance Imaging (MRI) are useful imaging modality in such cases. Surgical exploration with histopathological examination confirms the diagnosis of gossypiboma. CONCLUSION: In a postoperative patient who presents with chest pain and intrathoracic mass, gossypiboma should be a differential diagnosis even it is rare to occur in thorax. AD - Department of General Surgery, All India Institute of Medical Sciences, Patna, India. Electronic address: dranil4@gmail.com. Department of General Surgery (Trauma & Emergency), All India Institute of Medical Sciences, Bhuvneshwar, India. Electronic address: drshivanita@gmail.com. Department of Surgical Discipline, All India Institute of Medical Sciences, New Delhi, India. Electronic address: drrajinderparshad@aiims.ac.in. Department of Anaesthesia, Patna Medical College & Hospital, Patna, India. Electronic address: dr.rekha911@gmail.com. Department of Paediatric Surgery, All India Institute of Medical Sciences, Patna, India. Electronic address: bindeyster@gmail.com. AN - 29751199 AU - Kumar, A. AU - Paswan, S. S. AU - Prashad, R. AU - Kumari, R. AU - Kumar, B. C2 - PMC5994740 DO - 10.1016/j.ijscr.2018.04.024 DP - NLM ET - 2018/05/12 KW - Gauze piece Gossypiboma Intrapericardial Intrathoracic Tof LA - eng N1 - 2210-2612 Kumar, Anil Paswan, Shiv Shankar Prashad, Rajinder Kumari, Rekha Kumar, Bindey Journal Article Int J Surg Case Rep. 2018;47:75-79. doi: 10.1016/j.ijscr.2018.04.024. Epub 2018 May 3. PY - 2018 SN - 2210-2612 (Print) 2210-2612 SP - 75-79 ST - Intrapericardial gossypiboma: Rare cause of intrathoracic mass T2 - Int J Surg Case Rep TI - Intrapericardial gossypiboma: Rare cause of intrathoracic mass VL - 47 ID - 213 ER - TY - JOUR AB - We present two cases of pelvic pin migration after operations for Developmental Dysplasia of Hip (DDH). The wire was used for stabilization of the hips after open reduction for neglected unreduced DDH. The pins were protruding towards the bladder and they were all recognized at late follow up. This unusual migration of Kirschner wires into the pelvis has not been reported previously. AD - Kocaeli University School of Medicine, Department of Orthopaedics and Traumatology, Kocaeli, Turkey S.B. Istinye Devlet Hastanesi Orthopaedics and Traumatology Clinic, Istanbul, Turkey AU - Memişoǧlu, K. AU - Buluç, L. AU - Çirpici, Y. AU - Şarlak, A. Y. DB - Scopus IS - 2 M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2009 SP - 142-144 ST - Intrapelvic pin migration T2 - Anatolian Journal of Clinical Investigation TI - Intrapelvic pin migration UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77953449753&partnerID=40&md5=8820860da329969a48dcfc1fef361c86 VL - 3 ID - 1487 ER - TY - JOUR AB - PURPOSE: Retained surgical items result in substantial morbidity, health care-related expense, and legal liability. This study determines the performance of a protocol for locating surgical items after a miscount, in which intraoperative radiography included a radiograph of the unaccounted for item. METHODS: Institutional review board approval was obtained. In 20,820 operations performed between January 1, 2011 and April 1, 2013, a total of 183 consecutive surgical miscounts occurred, involving 180 patients (97 male, 83 female; median age: 55 years). Departmental protocol mandated that a radiograph of an example of the potentially retained item be taken simultaneously with each patient intraoperative radiograph. Three board-certified radiologists retrospectively reviewed these radiographs and follow-up imaging, achieving consensus on interpretation. Adherence to institutional protocol was assessed. Demographic data, surgical documentation, and clinical follow-up data were recorded. RESULTS: The incidence of surgical miscounts was 0.9% (183 of 20,820). Only 9% (17 of 183) were resolved by discovery: outside the patient (8 cases); on intraoperative radiographs (5 cases); incidentally on follow-up radiographs (2 cases); and on retrospective review (2 cases). The false-negative rate was 44% (4 of 9). Neither of the 2 retained needles discovered postoperatively was removed. The procedures most prone to miscounts were: esophagogastrectomy (33%; 2 of 6); liver transplant (18%; 12 of 66); and Whipple procedure (16%; 7 of 44). Needles (65%) and sponges (9%) were the items that were overlooked most often. Adherence to the protocol of imaging an example of a potentially retained item was 91% (167 of 183). CONCLUSIONS: Despite good adherence to a protocol of imaging the potentially retained items, small needles often were not visualized on intraoperative radiographs and were not subsequently removed, without known adverse events. This finding suggests that intraoperative radiography for small needles may be unnecessary, but further study is required. AD - Department of Radiology, Montefiore Medical Center & Albert Einstein School of Medicine, New York, New York. Electronic address: wwalter@montefiore.org. Department of Radiology, Montefiore Medical Center & Albert Einstein School of Medicine, New York, New York. AN - 26044645 AU - Walter, W. R. AU - Amis, E. S., Jr. AU - Sprayregen, S. AU - Haramati, L. B. DA - Aug DO - 10.1016/j.jacr.2015.03.005 DP - NLM ET - 2015/06/06 IS - 8 KW - Female Foreign Bodies/*diagnostic imaging/*epidemiology Humans Incidence Male Medical Errors/prevention & control/*statistics & numerical data Middle Aged Monitoring, Intraoperative/*statistics & numerical data New York/epidemiology Radiography, Interventional/*statistics & numerical data Reproducibility of Results Risk Assessment Sensitivity and Specificity Surgical Procedures, Operative/*statistics & numerical data Intraoperative radiograph OR miscount retained surgical item LA - eng N1 - 1558-349x Walter, William R Amis, E Stephen Jr Sprayregen, Seymour Haramati, Linda B Journal Article United States J Am Coll Radiol. 2015 Aug;12(8):824-9. doi: 10.1016/j.jacr.2015.03.005. Epub 2015 Jun 1. PY - 2015 SN - 1546-1440 SP - 824-9 ST - Intraoperative radiography for evaluation of surgical miscounts T2 - J Am Coll Radiol TI - Intraoperative radiography for evaluation of surgical miscounts VL - 12 ID - 162 ER - TY - JOUR AD - Department of Surgery, University of Wisconsin, Madison, Wisconsin, USA AN - 127594299. Language: English. Entry Date: 20180207. Revision Date: 20180207. Publication Type: Article AU - Vande Walle, Kara AU - Greenberg, Caprice DB - ccm DO - 10.1136/bmjqs-2017-006907 DP - EBSCOhost IS - 2 KW - Surgery, Operative Intraoperative Care -- Standards Teamwork Cognition Productivity Patient Safety Automation Serial Publications Prostatectomy Task Performance and Analysis Surgical Count Procedure N1 - commentary; editorial. Journal Subset: Blind Peer Reviewed; Europe; Expert Peer Reviewed; Health Services Administration; Peer Reviewed; UK & Ireland. NLM UID: 101546984. PY - 2018 SN - 2044-5415 SP - 99-101 ST - Intraoperative non-technical skills: a critical target for improving surgical outcomes T2 - BMJ Quality & Safety TI - Intraoperative non-technical skills: a critical target for improving surgical outcomes UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=127594299&site=ehost-live&scope=site VL - 27 ID - 774 ER - TY - JOUR AB - Despite near-universal implementation of protocols for surgical sponges, instruments and needles, incidents of retained surgical foreign bodies (RSFB) continue to be a significant patient safety challenge. We report a case of a 29-year-old woman who presented with small intestinal obstruction caused by complete intraluminal migration of a retained surgical sponge into the intestine 9 months after cesarean section. The diagnosis was confirmed by plain abdominal radiograph. The patient underwent exploratory laparotomy, sponge removal and became completely asymptomatic. Although safety standards for hospital employees have been developed during the past decades, no detection system to date has been evaluated as a replacement for traditional manual counting protocols and procedures. The best approach is the prevention of this condition, which can be achieved by implementation of standardized institutional regulations and strict adherence to them. Perhaps, with increasing use of the new technologies as adjunct to the counting, the incidence of RSFB will fall dramatically. AD - Department of General Surgery, Hera General Hospital, Makkah, Saudi Arabia al-rafie@hotmail.com. Department of General Surgery, Hera General Hospital, Makkah, Saudi Arabia. AN - 24964441 AU - Rafie, B. A. AU - AbuHamdan, O. J. AU - Trengganu, N. S. C2 - PMC3813552 DA - May 9 DO - 10.1093/jscr/rjt032 DP - NLM ET - 2013/01/01 IS - 5 LA - eng N1 - 2042-8812 Rafie, Basmah A AbuHamdan, Omar J Trengganu, Nawal S Case Reports J Surg Case Rep. 2013 May 9;2013(5):rjt032. doi: 10.1093/jscr/rjt032. PY - 2013 SN - 2042-8812 (Print) 2042-8812 ST - Intraluminal migration of retained surgical sponge as a cause of intestinal obstruction T2 - J Surg Case Rep TI - Intraluminal migration of retained surgical sponge as a cause of intestinal obstruction VL - 2013 ID - 133 ER - TY - JOUR AB - Intraluminal duodenal diverticulum (IDD) is a rare congenital anomaly. We present the report of an 8-year-old girl who had an entrapped coin in an IDD for 3 years that was associated with recurrent pancreatitis. Besides, a duodenoduodenal intussusception was found during the course of investigation and it seemed that a concomitant duodenal polyp contributed to the development of the intussusception. In view of the rarity of each of the aforementioned situations and the improbability of these conditions occurring together, this unusual and possibly unique case is therefore reported here. © 2014 . AD - Department of Diagnostic Radiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan Department of Pediatric Surgery, Shin Kong Wu Ho Su Memorial Hospital, Taipei, Taiwan Department of Pediatrics, Shin Kong Wu Ho Su Memorial Hospital, Taipei, Taiwan AU - Peng, H. L. AU - Su, C. T. AU - Chang, C. Y. AU - Lau, B. H. DB - Scopus DO - 10.1016/j.fjs.2014.08.004 IS - 6 KW - Coin Duodenal diverticulum Intussusception Pancreatitis Polyp M3 - Article N1 - Export Date: 10 November 2020 PY - 2014 SP - 236-239 ST - Intraluminal duodenal diverticulum in a child concomitant with an entrapped coin and a duodenal polyp T2 - Formosan Journal of Surgery TI - Intraluminal duodenal diverticulum in a child concomitant with an entrapped coin and a duodenal polyp UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84922688432&doi=10.1016%2fj.fjs.2014.08.004&partnerID=40&md5=7e0f2bdacce043edfa99f3f1748b88b5 VL - 47 ID - 1294 ER - TY - JOUR AB - The purpose of this manuscript was to provide a better understanding of patients with intralenticular foreign bodies (FBs) and also to review the reported cases, including clinical presentation, diagnosis, management, and visual outcome. A 50-year-old male was referred to our clinic with suspected intraocular FB. Under slit-lamp examination, a full-thickness corneal wound with localized corneal edema at the temporal lower peri-limbal area was revealed. Seidel test did not indicate any wound leakage. The corresponding iris was depigmented, but there was no penetrating hole. The anterior chamber was deep with cells, but the lens, vitreous, and fundus were normal. B-scan ultrasonography and orbital computed tomography were performed, but no intraocular FB was detected. On the 2(nd) day, a zonal cortical cataract and posterior subcapsular cataract formed rapidly. Left-eye bare vision dramatically decreased from 20/100 to counting fingers. One month later, the patient received elective extracapsular cataract extraction. A fine metal thread was completely embedded in the lens; the lens and FB were removed together during the operation. The posterior capsule was not injured; an intraocular lens was implanted in the capsular bag. Two months postoperatively, left-eye vision had returned to 20/25. No adverse events were noted during the follow-up period. In addition to the case report, some 28 previously reported cases of intralenticular FB are reviewed here. Patient demographics, time and course of management, and visual outcome are all summarized and compared. AD - Department of Ophthalmology, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan. Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan. AN - 30993070 AU - Lin, Y. C. AU - Kuo, C. L. AU - Chen, Y. M. C2 - PMC6432851 DA - Jan-Mar DO - 10.4103/tjo.tjo_88_18 DP - NLM ET - 2019/04/18 IS - 1 KW - Intralenticular foreign body intraocular foreign body metal foreign body LA - eng N1 - 2211-5072 Lin, Yen-Chun Kuo, Chin-Liang Chen, Yan-Ming Case Reports Taiwan J Ophthalmol. 2019 Jan-Mar;9(1):53-59. doi: 10.4103/tjo.tjo_88_18. PY - 2019 SN - 2211-5056 (Print) 2211-5056 SP - 53-59 ST - Intralenticular foreign body: A case report and literature review T2 - Taiwan J Ophthalmol TI - Intralenticular foreign body: A case report and literature review VL - 9 ID - 228 ER - TY - JOUR AB - Introduction Endobronchial foreign bodies have been occasionally reported to cause pediatric brain abscesses. We present the unusual case of an adult with brain abscess caused by an occult endobronchial foreign body. Case Report A 43 year old man presented with 1 month of fever and headaches worsening over 2 days prior to presentation. He also noted 4-5 days of nausea, vomiting, sore throat and cough. His past medical history was significant for post-traumatic stress disorder, anxiety, depression and substance abuse. Home medications included suboxone, fluoxetine, prazosin and trazodone. Physical exam on presentation showed fever (101.3F) but was otherwise normal. Lumbar puncture revealed white blood cell count 5742 (93% neutrophils, 2% lymphocytes, 4% monocytes), no red blood cells, protein 259 mg/dl and glucose 18 mg/dl. Cultures of the blood and CSF were negative. MRI brain showed a 1.8 cm abscess in the temporal lobe with rupture into the ventricle (Figure 1A). Chest CT, performed to characterize a subtle left lower lobe opacity on CXR, showed an abnormality at the carina (Figure 1B). Flexible bronchoscopy revealed a foreign body at the carina extending into the right mainstem bronchus with significant purulent secretions and granulation tissue (Figure 1C). A dental bridge was removed using foreign body forceps (Figure 1D). (Figure Presented) Further history revealed that his current dental bridge was replacement for one that had been “lost” 1 year prior to presentation. He denied any recollection of this aspiration event. The patient was diagnosed with brain abscess and bacterial meningitis secondary to an occult chronic endobronchial foreign body. His symptoms resolved, and he was discharged on antibiotics. Discussion Brain abscess is uncommon in adults and usually develops through hematogenous spread or from a contiguous source. Pulmonary sources (chronic lung abscess, empyema or bronchiectasis) are implicated in less than 10% of cases. Foreign body aspiration leading to brain abscess is rare, with only a handful of case-reports primarily in the pediatric literature. It has been proposed that sharp objects in the airway penetrate the mucosal barrier and allow infiltration of bacteria into the pulmonary circulation with hematogenous spread to the brain. Flexible bronchoscopy may be used for airway inspection and initial attempts at removal of foreign bodies. However, had we known the nature of this object (large dental bridge), we would have opted to perform rigid bronchoscopy. Pulmonary sources, including foreign body aspiration, should be investigated in cases of brain abscess with an unknown cause. AD - S.J. Beesley, University of Utah, Salt Lake City, UT, United States AU - Beesley, S. J. AU - Timm, J. AU - Swaminathan, S. AU - Elstad, M. R. DB - Embase KW - buprenorphine plus naloxone trazodone prazosin glucose fluoxetine protein antibiotic agent brain abscess foreign body adult American society human dental bridge bronchoscopy case report fever foreign body aspiration airway brain nausea lymphocyte anxiety lumbar puncture neutrophil substance abuse drug therapy headache posttraumatic stress disorder medical history coughing sore throat granulation tissue bacterial meningitis leukocyte count lung abscess lung circulation male monocyte vomiting blood abscess temporal lobe rupture thorax erythrocyte bronchus suppuration forceps aspiration patient empyema bronchiectasis bacterium nuclear magnetic resonance imaging cerebrospinal fluid LA - English M3 - Conference Abstract N1 - L72053780 2015-11-05 PY - 2015 SN - 1073-449X ST - Intracranial abscess due to endobronchial foreign body in an adult T2 - American Journal of Respiratory and Critical Care Medicine TI - Intracranial abscess due to endobronchial foreign body in an adult UR - https://www.embase.com/search/results?subaction=viewrecord&id=L72053780&from=export http://www.atsjournals.org/doi/pdf/10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A5883 VL - 191 ID - 425 ER - TY - JOUR AB - Most of the foreign bodies detected in adult gastrointestinal systems are accidentally swallowed pins. In this study, we presented a case with intracolonic multiple pebbles. A 20-year-old man was admitted to emergency surgery policlinic for abdominal pain for 2 d without any alleviation or aggravation. His upright plain abdominal radiographic imaging revealed about 30-40 overt dense opacities in lumen of colonic segments, with oval and well shaped contours, each approximately 1 cm × 1 cm in size. The multiplanar reconstructions and three- dimensional images combined with sectional screening showed that all pebbles had passed completely into the colon and no foreign bodies had remained in the ileal segments. On psychiatric assessment, he was found to have immature personality features, difficulty in over- coming stressors and adaptation disorder. He recovered by conservative management and radiographic monitoring applied during his follow-up. Thus, it can be concluded that, in differential diagnosis of abdominal pain in adult ages, though less frequently seen than in children, gastrointestinal system foreign bodies should always be kept in mind and it should be considered that ingestion of pebbles may be one of the factors contributing to abdominal pain particularly in young adults with psychiatric problems. In such cases suspected of having foreign bodies which cannot be detected by plain films, abdominal tomography can be an alternative for diagnostic imaging. © 2006 The WJG Press. All rights reserved. AD - Gulhane Military Medical Academy, Department of Emergency Medicine, Ankara, Turkey Gulhane Military Medical Academy, Department of General Surgery, Ankara, Turkey AU - Eryilmaz, M. AU - Ozturk, O. AU - Mentes, O. AU - Soylu, K. AU - Durusu, M. AU - Oner, K. DB - Scopus DO - 10.3748/wjg.v12.i37.6074 IS - 37 KW - Current approach Intracolonic multiple pebbles Radiographic imaging M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2006 SP - 6074-6076 ST - Intracolonic multiple pebbles in young adults: Radiographic imaging and conventional approach to a case T2 - World Journal of Gastroenterology TI - Intracolonic multiple pebbles in young adults: Radiographic imaging and conventional approach to a case UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33750259031&doi=10.3748%2fwjg.v12.i37.6074&partnerID=40&md5=7f6580ff49a505c7b32771f391be282e VL - 12 ID - 1576 ER - TY - JOUR AB - Background: An intracardiac foreign body causing recurrent fungemia is a rare clinical situation. Clinicians should be that aware of rare sources of sepsis despite a thorough history and examination. Results: The authors describe a 63 year-old man, with unremarkable past medical history, who presented with a fever for 2 weeks. Blood cultures persistently grew Candida albicans and Streptococcus constellatus. Echocardiogram assessment showed a suspected vegetation over the tricuspid valve. Surgical exploration with median sternotomy and cardiopulmonary bypass revealed a tooth-pick impacted within the right atrium surrounded by vegetation. The authors postulate accidental ingestion of the foreign body and translocation into the right atrium via the esophagus and thoracic cavity. Conclusion: Surgical removal of symptomatic intracardiac foreign bodies is highly recommended. © 2020 Wiley Periodicals LLC AD - Department of Cardiothoracic Surgery, Queen Mary Hospital, Hong Kong AU - Wong, M. K. H. AU - Rocha, B. A. AU - Au, T. W. K. DB - Scopus DO - 10.1111/jocs.14875 IS - 10 KW - candida endocarditis intracardiac foreign body tricuspid valve M3 - Article N1 - Export Date: 10 November 2020 PY - 2020 SP - 2844-2846 ST - Intracardiac foreign body: A rare cause of recurrent fungemia T2 - Journal of Cardiac Surgery TI - Intracardiac foreign body: A rare cause of recurrent fungemia UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85088097229&doi=10.1111%2fjocs.14875&partnerID=40&md5=7d1ae5f9295e8d4ac3e7bceea3e5a425 VL - 35 ID - 953 ER - TY - JOUR AB - Clips inserted during laparoscopic cholecystectomy (LC) may migrate into the biliary system and function as a nidus for the formation of gallstones. Here, we present a series of 4 patients who presented with this rare complication 5-17 years after LC. All 4 patients presented with symptomatic choledocholithiasis with biochemical and radiological signs of biliary obstruction. Three patients also had fever and infectious parameters, compatible with concurrent cholangitis. All patients successfully underwent endoscopic retrograde cholangiopancreatography (ERCP) with papillotomy and stone extraction. Patients with cholangitis also had antibiotic treatment. In 3 patients, obstruction of the common bile duct was caused by a single, relatively large stone that had formed around a clip (supposedly the cystic duct clip). In 1 patient, multiple stones had formed around an intrabiliary migrated cluster of coils that had been used for arterial embolization of a pseudo-aneurysm of the right hepatic artery. In conclusion, surgical clips and coils can migrate into the biliary tract and serve as a nidus for the formation of bile duct stones. Although rare, this complication should caution surgeons not to place clips "at random" during cholecystectomy. Patients with this rare complication are best managed by ERCP in combination with sphincterotomy and stone extraction. © 2018 The Author(s). Published by S. Karger AG, Basel. AD - Department of Surgery, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, AZ NL-1105, Netherlands Department of Gastroenterology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands AU - Schreuder, A. M. AU - Van Gulik, T. M. AU - Rauws, E. A. J. DB - Scopus DO - 10.1159/000493253 IS - 3 KW - Bile duct injury Cholecystectomy Clip migration Endoscopic retrograde cholangiopancreatography Foreign body migration M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2018 SP - 686-691 ST - Intrabiliary Migrated Clips and Coils as a Nidus for Biliary Stone Formation: A Rare Complication following Laparoscopic Cholecystectomy T2 - Case Reports in Gastroenterology TI - Intrabiliary Migrated Clips and Coils as a Nidus for Biliary Stone Formation: A Rare Complication following Laparoscopic Cholecystectomy UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85057731122&doi=10.1159%2f000493253&partnerID=40&md5=970ead0b5c76255adecd8788581fc0de VL - 12 ID - 1065 ER - TY - JOUR AB - A retained surgical sponge or gossypiboma is a rare and an underreported complication occurring most commonly after abdominal surgeries. The clinical presentation as well as the time of presentation is variable with about one third of patients being asymptomatic. The diagnosis is challenging because of marked variation in the presentation and imaging plays a crucial role in diagnosis. We report a 30-year old Asian woman with prior history of Caesarean section who presented with persistent abdominal pain since surgery and underwent imaging in December 2012. The case is interesting as she had two intraabdominal gossypibomas with different appearances on computerized tomography. One was suggested to be a retained foreign body while the other was initially misinterpreted as a solid ovarian mass. However, on ultrasound, both lesions showed similar appearance and the left lower abdominal solid mass was also suggested to be a retained foreign body which was then confirmed on laparotomy. © 2019, Pakistan Medical Association. All rights reserved. AD - Aga Khan University Hospital, Karachi, Pakistan AU - Fatima, K. DB - Scopus IS - 1 KW - Computerized tomography Gossypiboma Intraabdominal Surgical sponge Ultrasound M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 123-126 ST - Intraabdominal gossypibomas with variable ct appearance: A case report T2 - Journal of the Pakistan Medical Association TI - Intraabdominal gossypibomas with variable ct appearance: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85059267671&partnerID=40&md5=08e28b3ba1245403a1be00e9c019d4a4 VL - 69 ID - 1027 ER - TY - JOUR AB - Introduction. Intraabdominal abscesses are in 98-99% cases the result of secondary and only in 1-2% of primary peritonitis. They are easy and successfully diagnosed. Abdominal abscesses of unknown cause are extremely rare. Case Outline. The authors present a 68-year-old man, without significant data in past history, who suddenly developed epigastric pain, nausea, vomiting and leukocytosis which was treated with antibiotics resulting in the alleviation of complaints and reduction of white blood cells count. After five days ultrasonography showed incapsulated collection of dense fluid in the epigastrium confirmed by CT scan two days later. Upper endoscopy excluded ulcer and/or perforation of the stomach and duodenum. Under local anesthesia, through the upper part of the left rectal muscle, puncture followed by incision was done, and about 50 ml of dense pus was removed. Finger exploration of the cavity showed no foreign body within the cavity. Using drainage, the recovery was quick and uneventful. By preoperative and postoperative abdominal investigations no cause of the abscess was found. Two and a half years after surgery the patient remained symptom-free with normal clinical, laboratory and ultrasonographic findings. Conclusion. The authors presented an intraabdominal abscess of unknown cause that was successfully treated with antibiotics, percutaneous puncture and drainage under local anaesthesia. In spite of all diagnostic methods the cause of the abscess could not be found. Thus, such a possibility, although being rare, should be taken into account. © 2012. Centre for Evaluation in Education and Science. AD - Univerzitet u Beogradu, Medicinski fakultet, Klinički centar Srbije, Serbia Klinika za hematologiju, Klinički centar Srbije, Beograd, Serbia AU - Radoje, C. AU - Nikica, G. AU - Stojan, L. AU - Nataša, C. DB - Scopus DO - 10.2298/SARH1202094C IS - 1-2 KW - Abdomen Abscess Drainage Incision Local anaesthesia Puncture M3 - Article N1 - Export Date: 10 November 2020 PY - 2012 SP - 94-96 ST - Intraabdominal abscessus of unknown etiology T2 - Srpski Arhiv za Celokupno Lekarstvo TI - Intraabdominal abscessus of unknown etiology UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84874177603&doi=10.2298%2fSARH1202094C&partnerID=40&md5=b54fd90739f19377242a84fc43a61e8c VL - 140 ID - 1396 ER - TY - JOUR AB - Gossypibomas are masses formed by accidentally retained cotton matrix anywhere in the body, following a surgical procedure. It has catastrophic effects not only on patients but also on the health professionals and health care providers. We have retrospectively reviewed 6 patients of intra-abdominal gossypibomas who had presented over a 10-year period, to our centre. The relevant preoperative and intraoperative details along with the clinical course of these patients have been described. Through the management of these patients, we have shared our experience in relation to the clinical presentations, probable risk factors, and radiological features for diagnosis and treatment, along with the ethical and medicolegal implications of the issue. The safety measures that exist are also reviewed. An intraoperative “correct count” during a surgical operation does not always exclude the possibility of a gossypiboma or a retained foreign body. Increased awareness, familiarity with the existing local protocols, and strict adherence of these protocols, along with open communication, are essential in minimizing the frequency of such events. A concerted effort by the entire surgical team is crucial. Newer technology such as barcoding of sponges and radiofrequency identification (RFID) tagging may help decrease the occurrence of this problem. © 2020, Association of Surgeons of India. AD - Upper GI Surgery Unit, Division of General Surgery, Christian Medical College and Hospital, Vellore, Tamil Nadu, India AU - Iype, G. R. AU - Samarasam, I. AU - Senthilnathan, K. AU - Yacob, M. AU - Abraham, V. P. DB - Scopus DO - 10.1007/s12262-020-02511-5 KW - Gossypiboma Retained surgical items Retained surgical sponge Textiloma M3 - Article N1 - Export Date: 10 November 2020 PY - 2020 ST - Intra-abdominal Gossypibomas: Clinical Manifestations, Risk Factors and Prevention T2 - Indian Journal of Surgery TI - Intra-abdominal Gossypibomas: Clinical Manifestations, Risk Factors and Prevention UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85087940382&doi=10.1007%2fs12262-020-02511-5&partnerID=40&md5=b36f09d1bcbf9dd96ccc3c33fb2351ac ID - 977 ER - TY - JOUR AD - Department of General Surgery, Oxford University Hospitals NHS Trust, Oxford, Oxford, United Kingdom Department of General Surgery, Stoke Mandeville Hospital, Stoke Mandeville, Buckinghamshire, United Kingdom AU - Mannu, G. S. AU - Pawelec, K. DB - Scopus DO - 10.1136/bcr-2014-207717 M3 - Article N1 - Export Date: 10 November 2020 PY - 2014 ST - Intra-abdominal abscess formation from the ingestion of a fish bone T2 - BMJ Case Reports TI - Intra-abdominal abscess formation from the ingestion of a fish bone UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84936148019&doi=10.1136%2fbcr-2014-207717&partnerID=40&md5=00e042a72bd9a421fba3eaeeb609f3e1 VL - 2014 ID - 1275 ER - TY - JOUR AB - We present the case of a 42-year-old female who presented to our emergency department (ED) complaining of epigastric pain for four days. She had been seen in the outpatient department and ED previously for evaluation, but continued to experience epigastric pain with fever. Emergency panendoscopy was performed and a toothpick was discovered impacted in the duodenal bulb. The gastroenterologist was unable to remove the toothpick endoscopically. Computed tomography of the abdomen revealed a long and straight hyperdense foreign body, and intra-abdominal abscess formation. An emergency laparotomy was performed. The patient recovered gradually and was discharged 11 days later. She could not remember when she swallowed the wooden toothpick, but guessed that it was while out drinking. There is an old wives' tale in Taiwan that putting a toothpick in the cup while drinking beer reduces the likelihood of abdominal distention from the carbonation of the beer. © 2008 International Society for Infectious Diseases. AD - Department of Emergency Medicine, Mackay Memorial Hospital, Taipei, 10449, Taiwan Mackay Medicine, Nursing and Management College, Taipei, 112, Taiwan College of Continuing Education, Aletheia University, Taipei, 251, Taiwan Department of Anesthesiology, Mackay Memorial Hospital, Taipei, 10449, Taiwan School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, 110, Taiwan Department of Internal Medicine, University of Massachusetts-Memorial Medical Center, Worcester, MA, United States AU - Su, Y. J. AU - Lai, Y. C. AU - Chen, C. C. AU - Tang, C. DB - Scopus DO - 10.1016/j.ijid.2008.10.001 IS - 5 KW - Duodenal perforation Intra-abdominal abscess Pneumoperitoneum Toothpick M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2009 SP - e264-e266 ST - Intra-abdominal abscess caused by toothpick injury T2 - International Journal of Infectious Diseases TI - Intra-abdominal abscess caused by toothpick injury UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-68949172092&doi=10.1016%2fj.ijid.2008.10.001&partnerID=40&md5=15ec1ebc83ac8008984f1287111323ae VL - 13 ID - 1489 ER - TY - JOUR AB - Vaginal foreign bodies in girls may be accidental, self-inflicted or secondary to child abuse. These may causes a number of complications like Infections, abscess formation, intestinal perforation, vaginal discharge and internal fistulae. We are presenting a case of a 13 years old girl who presented with a supra-pubic mass and dysuria. X-ray showed a radio-opaque shadow in pelvis. The child was admitted in medical ward with the diagnosis of bladder stone and UTI. She was pouring frank pus from the vagina. On rectal digital examination a hard foreign body was felt in the rectum. Investigations revealed that she had a large pelvic collection, a sharp wooden Foreign Body (FB) extending from the rectum through the vagina in to the urinary bladder forming a bladder stone. Patient also developed recto-vaginal and vesico-vaginal fistulae. Foreign body was removed along with the bladder stone, pelvic abscess drained and colostomy was performed. Later repair of vesico-vaginal fistula were performed, recto-vaginal fistula closed spontaneously and colostomy closed. Patient became fully continent for urine and feces after completion of surgical procedures. A careful history from the child revealed that she had inserted the foreign body herself as a self-exploring practice. AD - National Institute of Rehabilitation Medicine Islamabad, Pakistan The Children's Hospital, PIMS, Islamabad, Pakistan AU - Jan, I. A. AU - Arif, K. AU - Anwar ul, Haq AU - Gondal, M. AU - Orakzai, H. DB - Scopus IS - 2 KW - Complications Internal fistula Vaginal foreign body Wooden M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2010 SP - 470-473 ST - Intra vaginal wooden foreign body causing multiple internal fistulae and bladder stone in a 12 years girl T2 - Pakistan Journal of Medical Sciences TI - Intra vaginal wooden foreign body causing multiple internal fistulae and bladder stone in a 12 years girl UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77954561146&partnerID=40&md5=c102222506514d5cdd095c12aee389d4 VL - 26 ID - 1462 ER - TY - JOUR AB - A type of fixation failure of Dynamic Hip Screw system (DHS) is presented following a collapse of intertrochanteric fracture fixation. The patient presented three months after DHS fixation with severe lower abdominal pain, painful stiff hip and an uncontrolled diabetes mellitus. The radiographic examination of pelvis revealed intrapelvic presence of DHS sliding screw. The intrapelvic total migration of sliding screw has never been reported so far. AD - Department of Orthopedic Surgery, JPMC, Karachi 75510, Pakistan AU - Bhatti, A. AU - Abbasi, A. DB - Scopus IS - 6 KW - Failure Fixation Fracture Intertrochanteric Screw migration M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2007 SP - 371-373 ST - Intra pelvic total migration of sliding screw in intertrochanteric fracture T2 - Journal of the College of Physicians and Surgeons Pakistan TI - Intra pelvic total migration of sliding screw in intertrochanteric fracture UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-34548266050&partnerID=40&md5=179d7cf15f9fa31b45510572ae7058ce VL - 17 ID - 1564 ER - TY - JOUR AB - Intraluminal gossypiboma is a serious but avoidable complication during surgery which can be averted. The whole surgical team has to be vigilant especially during the closure of surgery, the time when fatigue makes every one a bit careless which can be costly both for the surgeon and increases the morbidity and mortality of the patient. Simple precautions like gauze pieces counting and tagging the gauze pieces with markers can prevent this. AD - A. Kr. Agarwal, Doctors' Chummury, 41 Eden Hospital Road, Kolkata-700073 West Bengal, India AU - Agarwal, A. Kr AU - Bhattacharya, N. AU - Mukherjee, R. AU - Akash Bora, A. DB - Embase IS - 3 KW - abdominal radiography adult article case report cholecystectomy female gauze dressing gossypiboma human intestine obstruction laparotomy postoperative complication surgical technique L1 - internal-pdf://1101513929/luminal.pdf LA - English M3 - Article N1 - L351947447 2008-08-20 PY - 2008 SN - 1682-024X SP - 461-463 ST - Intra luminal gossypiboma T2 - Pakistan Journal of Medical Sciences TI - Intra luminal gossypiboma UR - https://www.embase.com/search/results?subaction=viewrecord&id=L351947447&from=export VL - 24 ID - 601 ER - TY - JOUR AB - Dr. Verna Gibbs describes the "NoThing Left Behind" Program designed to eliminate retained devices from surgical procedures. She explains the genesis of the program along with adjuncts to counting including computer-assisted sponge count, radiofrequency detection system, radiofrequency identification system, and the Sponge ACCOUNTing system. She provides comments on the use of these adjuncts with responses on their effectiveness on improving safety. AN - 22093170 AU - Gibbs, V. DA - Nov-Dec DO - 10.1111/j.1945-1474.2011.00171.x DP - NLM ET - 2011/11/19 IS - 6 KW - Checklist Foreign Bodies/*prevention & control Humans Medical Errors/*prevention & control Patient Safety/*standards Quality Improvement/standards Surgical Procedures, Operative/methods/*standards Surgical Sponges LA - eng N1 - 1945-1474 Gibbs, Verna Interview United States J Healthc Qual. 2012 Nov-Dec;34(6):21-6. doi: 10.1111/j.1945-1474.2011.00171.x. Epub 2011 Nov 11. PY - 2012 SN - 1062-2551 SP - 21-6 ST - Interview with a quality leader: Dr. Verna Gibbs on surgical safety. Interview by Susan V. White T2 - J Healthc Qual TI - Interview with a quality leader: Dr. Verna Gibbs on surgical safety. Interview by Susan V. White VL - 34 ID - 117 ER - TY - JOUR AB - Dr. Verna Gibbs describes the ' No Thing Left Behind' Program designed to eliminate retained devices from surgical procedures. She explains the genesis of the program along with adjuncts to counting including computer-assisted sponge count, radiofrequency detection system, radiofrequency identification system, and the Sponge ACCOUNTing system. She provides comments on the use of these adjuncts with responses on their effectiveness on improving safety. AN - 104439140. Language: English. Entry Date: 20121126. Revision Date: 20200708. Publication Type: Journal Article AU - White, Susan V. DB - ccm DO - 10.1111/j.1945-1474.2011.00171.x DP - EBSCOhost IS - 6 KW - Retained Instruments -- Prevention and Control Surgery, Operative Quality Improvement Leadership Surgical Count Procedure -- Methods Operating Room Personnel Medical Practice, Evidence-Based Protocols Process Assessment (Health Care) Clinical Information Systems Computer Aided Design Radio Waves N1 - interview. Journal Subset: Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Health Services Administration; Peer Reviewed; USA. Special Interest: Evidence-Based Practice; Patient Safety; Perioperative Care; Quality Assurance. NLM UID: 9202994. PMID: NLM22093170. PY - 2012 SN - 1062-2551 SP - 21-26 ST - Interview with a Quality Leader: Dr. Verna Gibbs on Surgical Safety T2 - Journal for Healthcare Quality: Promoting Excellence in Healthcare TI - Interview with a Quality Leader: Dr. Verna Gibbs on Surgical Safety UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104439140&site=ehost-live&scope=site VL - 34 ID - 830 ER - TY - JOUR AB - Background: The World Health Organisation Surgical Safety Checklist (SSC) improves surgical outcomes and the research question is no longer 'does the SSC work?' but, 'how to make the SSC work?' Evidence for implementation strategies in low-income countries is sparse and existing strategies are heavily based on long-term external support. Short but effective implementation programs are required if widespread scale up is to be achieved. We designed and delivered a four-day pilot SSC training course at a single hospital centre in the Republic of Congo, and evaluated the implementation after one year. We hypothesised that participants would still be using the checklist over 50% of the time. Method: We taught the four-day SSC training course at Dolisie hospital in February 2014, and undertook a mixed methods impact evaluation based on the Kirkpatrick model in May 2015. SSC implementation was evaluated using self-reported questionnaire with a 3 point Likert scale to assess six key process measures. Learning, behaviour, organisational change and facilitators and inhibitors to change were evaluated with questionnaires, interviews and focus group discussion. Results: Seventeen individuals participated in the training and seven (40%) were available for impact evaluation at 15 months. No participant had used the SSC prior to training. Over half the participants were following the six processes measures always or most of the time: confirmation of patient identity and the surgical procedure (57%), assessment of difficult intubation risk (72%), assessment of the risk of major blood loss (86%), antibiotic prophylaxis given before skin incision (86%), use of a pulse oximeter (86%), and counting sponges and instruments (71%). All participants reported positive improvements in teamwork, organisation and safe anesthesia. Most participants reported they worked in helpful, supportive and respectful atmosphere; and could speak up if they saw something that might harm a patient. However, less than half felt able to challenge those in authority. Conclusion: Our study demonstrates that a 4-day pilot course for SSC implementation resulted in over 50% of participants using the SSC at 15 months, positive changes in learning, behaviour and organisational change, but less impact on hierarchical culture. The next step is to test our novel implementation strategy in a larger hospital setting. AD - M.C. White, Mercy Ships, Department of Medical Capacity Building, Port of Pointe Noire, Congo AU - White, M. C. AU - Peterschmidt, J. AU - Callahan, J. AU - Fitzgerald, J. E. AU - Close, K. L. DB - Embase Medline DO - 10.1186/s12992-017-0266-0 IS - 1 KW - anesthesia antibiotic prophylaxis article bleeding change management checklist Congo education program educational model follow up health care planning hospital human information processing intubation Kirkpatrick model Likert scale patient safety pilot study priority journal program evaluation pulse oximeter questionnaire risk assessment self report skin incision structured interview surgical safety checklist surgical sponge teamwork work environment World Health Organization LA - English M3 - Article N1 - L616995125 2017-07-04 2017-07-07 PY - 2017 SN - 1744-8603 ST - Interval follow up of a 4-day pilot program to implement the WHO surgical safety checklist at a Congolese hospital T2 - Globalization and Health TI - Interval follow up of a 4-day pilot program to implement the WHO surgical safety checklist at a Congolese hospital UR - https://www.embase.com/search/results?subaction=viewrecord&id=L616995125&from=export http://dx.doi.org/10.1186/s12992-017-0266-0 VL - 13 ID - 373 ER - TY - JOUR AB - Background: 18F-Fluorodeoxyglucose positron emission computerised tomography (FDG-PET-CT) is commonly used to aid the diagnosis of large vessel vasculitis (LVV). Its precise role and sensitivity during follow-up of LVV remains to be defined, and use is typically restricted to investigation of an unexplained acute phase response. We have encountered an additional limitation in LVV patients with synthetic arterial grafts, namely interpretation of FDG uptake confined to the graft. This is typically reported as vasculitic activity or infection, even in the absence of supportive clinical data. Objectives: To investigate non-specific uptake of FDG by synthetic arterial grafts in LVV. Methods: Twelve patients with FDG-uptake localised to arterial grafts were identified, 10 with LVV, and 2 with non-inflammatory aortopathy. The maximum standardised uptake values (SUV) for the grafts were quantified. The intensity of uptake by each graft and the native aorta was scored against constitutive hepatic uptake. Time after surgery, C-reactive protein, and infection screen results were obtained. Disease progression was estimated by magnetic resonance angiography (MRA). Results: Twelve patients (10 female, mean age 41.4 yrs, range 23-60) who had undergone graft surgery and FDG-PET scanning were identified, 8 with Takayasu arteritis (TA), 2 giant cell aortitis, 1 Marfan's syndrome and 1 non-inflammatory aortic wall degeneration (Table). The index case (patient 1) presented with fatigue 2 years post-surgery. An FDG-PET-CT demonstrated increased FDG uptake specifically localised to the graft site, raising concerns regarding active LVV or graft infection. However, blood indices including leukocyte count and acute phase reactants were normal, and repeat blood cultures revealed no infection. Study of nine other LVV patients revealed directly comparable findings (Table). The 2 patients with non-inflammatory disease also demonstrated significant uptake in aortic grafts, with no identifiable cause. The mean time post-surgery to first scan was 40 months (range 6-90). The mean maximum SUV of the grafts was (4.29±1.22). The uptake score in the grafts and native aorta relative to the liver were 2.83±0.39 versus 0.42±0.67 respectively (p<0.001). The CRP was not raised (mean ± SD 5.95±4.82, NR<10 mg/L), no infections were identified. Eight patients had repeat FDG-PET-CT scans with similar graft specific uptake identified. In 9 patients treatment was left unchanged. In 2 cases immunosuppression was increased and one received antibiotics, both without any change in FDG uptake. In those with LVV, immunosuppression has been subsequently weaned/withdrawn in all cases with no disease progression at 76.5 months (range 9-180). Conclusions: Although FDG-PET-CT scanning has proved useful for the diagnosis of active LVV, its role in the follow-up of patients on treatment remains undecided. FDG uptake confined to synthetic graft sites in LVV does not necessarily equate to infection or active vasculitis requiring treatment escalation. (Table Presented ) Uptake may represent a macrophage-driven foreign body reaction to the graft. Scans need to be interpreted cautiously and in conjunction with other clinical indices. AD - T. Youngstein, Rheumatology and Vascular Sciences, Imperial College London, London, United Kingdom AU - Youngstein, T. AU - Mukherjee, J. AU - Tombetti, E. AU - Humphreys, E. AU - Nash, J. AU - Andrews, J. AU - Mason, J. C. DB - Embase DO - 10.1136/annrheumdis-2015-eular.3366 KW - fluorodeoxyglucose f 18 C reactive protein acute phase protein antibiotic agent contact lens solution European artery graft human patient vasculitis rheumatology rheumatic disease infection surgery computer assisted tomography immunosuppressive treatment aorta follow up diagnosis disease course blood culture leukocyte count blood graft infection fatigue degeneration clinical study positron aortic wall aortitis acute phase response female aortic arch syndrome giant cell macrophage positron emission tomography magnetic resonance angiography liver aortic graft foreign body reaction inflammatory disease Marfan syndrome LA - English M3 - Conference Abstract N1 - L72151872 2016-01-16 PY - 2015 SN - 0003-4967 SP - 304 ST - Interpretation of 18F-fluorodeoxyglucose uptake by arterial grafts in patients with large vessel vasculitis-a conundrum T2 - Annals of the Rheumatic Diseases TI - Interpretation of 18F-fluorodeoxyglucose uptake by arterial grafts in patients with large vessel vasculitis-a conundrum UR - https://www.embase.com/search/results?subaction=viewrecord&id=L72151872&from=export http://dx.doi.org/10.1136/annrheumdis-2015-eular.3366 http://ard.bmj.com/content/74/Suppl_2/304.1.abstract?sid=b850bda6-ff4a-41b8-8852-eb8fdc4d5b2b VL - 74 ID - 429 ER - TY - JOUR AB - Medical implants have been rarely associated with the development of sarcomas. We report, to our knowledge, the first case of a high-grade epithelioid angiosarcoma developing in the capsule of an internal cardiac defibrillator implanted subcutaneously over the abdomen over 20 years ago. Although the internal cardiac defibrillator generator had been exchanged in the intervening years, recently, the patient showed a year-long history of systemic symptoms suspicious for implant infection, necessitating several internal cardiac defibrillator pocket hematoma evacuations, always with negative microbiologic cultures. Final reexploration identified suspicious tissue with excessive bleeding which was biopsied and proven to be angiosarcoma on histologic examination. Subsequent imaging demonstrated precipitous progression to liver and lung metastases. Though rare, foreign-body-related sarcoma should be considered in the differential diagnosis for presentations suggestive of hemorrhagic or infectious sequelae of medical implants; this case broadens the range of medical devices associated with angiosarcoma to include now very commonly used implantable medical devices. Crown Copyright © 2013 Published by Elsevier Inc. All rights reserved. AD - Department of Pathology, University of Michigan Health System, 4211 Medical Science i, 1301 Catherine, SPC 5602, United States Department of Cardiac Surgery, University of Michigan Health System, Ann Arbor, MI 48103, United States AU - Smith, S. C. AU - Bernacki, K. D. AU - Haft, J. W. AU - McHugh, J. B. DB - Scopus DO - 10.1016/j.carpath.2012.03.007 IS - 1 KW - Angiosarcoma Cardiac defibrillator Medical devices M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2013 SP - 105-108 ST - Internal cardiac defibrillator implant-associated angiosarcoma presenting as suspected implant pouch infection T2 - Cardiovascular Pathology TI - Internal cardiac defibrillator implant-associated angiosarcoma presenting as suspected implant pouch infection UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84870918890&doi=10.1016%2fj.carpath.2012.03.007&partnerID=40&md5=4a7d620605c901edfaa6778dd932cb16 VL - 22 ID - 1345 ER - TY - JOUR AB - Wound contraction and scar formation after cleft palate repair lead to growth impairment of the maxilla and midface. Myofibroblasts play a key role in these processes. The application of an interferon-γ (IFN-γ)-loaded collagen scaffold after surgery might reduce the differentiation of myofibroblasts. In this study, the tissue response to IFN-γ-loaded collagen scaffolds was evaluated after implantation in the palate of rats.Scaffolds, with or without IFN-γ, were implanted submucoperiosteally in the palate of two groups of 25 five-week-old male Wistar rats. Groups of five rats were sacrificed at 1, 2, 4, 8, and 16 weeks post-implantation and processed for histological analyses. On haematoxylin and eosin-stained sections, the cell density and number of giant cells within the scaffolds were determined. Blood vessels, inflammatory cells, and myofibroblasts were detected by immunohistochemistry. The data for cell density, blood vessels, and giant cells were compared with a two-way analysis of variance. The scores for myofibroblasts and inflammation were compared by a rank sum test.A mild and rapidly subsiding inflammatory and foreign body response was found in both groups. Angiogenesis had already begun after 1 week, showed a peak after 4 weeks, and declined thereafter. IFN-γ induced a faster influx of host cells and a major reduction in myofibroblast numbers. The scaffolds might be suitable for future applications in oral surgery. © The Author 2010. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. AD - Department of Orthodontics and Oral Biology, Radboud University Nijmegen Medical Centre, PO Box 910, 6500 HB Nijmegen, Netherlands Department of Biochemistry, Radboud University Nijmegen Medical Centre, Netherlands AU - Jansen, R. G. AU - Van Kuppevelt, T. H. AU - Daamen, W. F. AU - Kuijpers-Jagtman, A. M. AU - Von Den Hoff, J. W. DB - Scopus DO - 10.1093/ejo/cjp129 IS - 1 M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2011 SP - 1-8 ST - Interferon-γ-loaded collagen scaffolds reduce myofibroblast numbers in rat palatal mucosa T2 - European Journal of Orthodontics TI - Interferon-γ-loaded collagen scaffolds reduce myofibroblast numbers in rat palatal mucosa UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79551522292&doi=10.1093%2fejo%2fcjp129&partnerID=40&md5=491485fddaafc48db270a4ec33ec0929 VL - 33 ID - 1428 ER - TY - JOUR AD - Dept. of Paediatric Otolaryngology, Great Ormond Street Hospital, London, United Kingdom AU - Bajaj, Y. AU - Kapoor, K. AU - Jephson, C. G. AU - Albert, D. M. DB - Scopus IS - 3 M3 - Article N1 - Export Date: 10 November 2020 PY - 2012 SP - 167-172 ST - Intercollegiate exam - viva in paediatric otolaryngology - paediatric emergencies T2 - Otorhinolaryngologist TI - Intercollegiate exam - viva in paediatric otolaryngology - paediatric emergencies UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84857309638&partnerID=40&md5=651e087e2738e0ca5c123e3d0a97e57b VL - 4 ID - 1377 ER - TY - JOUR AB - Background: Intentional ingestion of foreign objects (IIFO) is common in the incarcerated population. This study was undertaken in order to better define clinical patterns of IIFO among prisoners. We sought to determine factors associated with the need for endoscopic and surgical therapy for IIFO. Methods: After obtaining permission to conduct IIFO research in incarcerated populations, study patients were identified by ICD-9 codes. Patient charts were reviewed for demographics; past medical history; IIFO characteristics; and diagnostic, endoscopic, and surgical findings. Univariate and multivariate analyses were performed using statistical software. Results: Thirty patients with 141 episodes of IIFO were identified. The mean number of ingested items per episode was 4.60. Endoscopy was performed in 97 of 141 IIFO instances, with failure to retrieve the ingested object in 21 of 97 cases (22%). Eleven instances (7.8%) required surgical intervention. On multivariate analyses, hospital admission was associated with elevated white blood cell count (odds ratio [OR] 1.4, P < 0.05) and number of items ingested (OR 1.3, P < 0.05). The need for endoscopy was independently associated with ingestion of multiple objects (OR 3.3, P < 0.05) and elevated white blood cell count (OR 1.3, P < 0.05). Surgical therapy was significantly associated with elevated white blood cell count (OR 1.6, P < 0.01) and with increasing number of ingested items (OR 1.07 per item, P < 0.05). Endoscopy is associated with significantly lower odds of surgery (OR 0.13, P < 0.01). Conclusions: Intentional ingestion of foreign objects continues to pose a significant human and economic burden. The need for admission or therapy is frequently associated with leukocytosis. Further investigation is warranted into resource-appropriate triage of patients who present with IIFO. © 2013 Elsevier Inc. All rights reserved. AD - D.C. Evans, Department of Surgery, Ohio State University, 395 W 12th Ave, Room 634D, Columbus, OH 43210-1267, United States AU - Dalal, P. P. AU - Otey, A. J. AU - McGonagle, E. A. AU - Whitmill, M. L. AU - Levine, E. J. AU - McKimmie, R. L. AU - Thomas, A. C. AU - Cook, C. H. AU - Papadimos, T. J. AU - Reilley, T. E. AU - Bergese, S. D. AU - Steinberg, S. M. AU - Stawicki, S. P. A. AU - Evans, D. C. DB - Embase Medline DO - 10.1016/j.jss.2013.04.078 IS - 1 KW - adult article clinical article software demography economic aspect emergency health service female foreign body gastrointestinal endoscopy gastrointestinal surgery hospital admission human ICD-9 ingestion leukocyte count leukocytosis male medical history medical record priority journal prisoner LA - English M3 - Article N1 - L52603543 2013-05-30 2013-10-07 PY - 2013 SN - 0022-4804 1095-8673 SP - 145-149 ST - Intentional foreign object ingestions: Need for endoscopy and surgery T2 - Journal of Surgical Research TI - Intentional foreign object ingestions: Need for endoscopy and surgery UR - https://www.embase.com/search/results?subaction=viewrecord&id=L52603543&from=export http://dx.doi.org/10.1016/j.jss.2013.04.078 VL - 184 ID - 469 ER - TY - JOUR AB - BACKGROUND: Intentional ingestion of foreign objects (IIFO) is common in the incarcerated population. This study was undertaken in order to better define clinical patterns of IIFO among prisoners. We sought to determine factors associated with the need for endoscopic and surgical therapy for IIFO. METHODS: After obtaining permission to conduct IIFO research in incarcerated populations, study patients were identified by ICD-9 codes. Patient charts were reviewed for demographics; past medical history; IIFO characteristics; and diagnostic, endoscopic, and surgical findings. Univariate and multivariate analyses were performed using statistical software. RESULTS: Thirty patients with 141 episodes of IIFO were identified. The mean number of ingested items per episode was 4.60. Endoscopy was performed in 97 of 141 IIFO instances, with failure to retrieve the ingested object in 21 of 97 cases (22%). Eleven instances (7.8%) required surgical intervention. On multivariate analyses, hospital admission was associated with elevated white blood cell count (odds ratio [OR] 1.4, P < 0.05) and number of items ingested (OR 1.3, P < 0.05). The need for endoscopy was independently associated with ingestion of multiple objects (OR 3.3, P < 0.05) and elevated white blood cell count (OR 1.3, P < 0.05). Surgical therapy was significantly associated with elevated white blood cell count (OR 1.6, P < 0.01) and with increasing number of ingested items (OR 1.07 per item, P < 0.05). Endoscopy is associated with significantly lower odds of surgery (OR 0.13, P < 0.01). CONCLUSIONS: Intentional ingestion of foreign objects continues to pose a significant human and economic burden. The need for admission or therapy is frequently associated with leukocytosis. Further investigation is warranted into resource-appropriate triage of patients who present with IIFO. AD - Department of Anesthesiology, The Ohio State University, Columbus, Ohio 43210, USA. AN - 23726238 AU - Dalal, P. P. AU - Otey, A. J. AU - McGonagle, E. A. AU - Whitmill, M. L. AU - Levine, E. J. AU - McKimmie, R. L. AU - Thomas, A. C. AU - Cook, C. H. AU - Papadimos, T. J. AU - Reilley, T. E. AU - Bergese, S. D. AU - Steinberg, S. M. AU - Stawicki, S. P. AU - Evans, D. C. DA - Sep DO - 10.1016/j.jss.2013.04.078 DP - NLM ET - 2013/06/04 IS - 1 KW - Academic Medical Centers/statistics & numerical data Adult Eating Endoscopy, Gastrointestinal/*statistics & numerical data Female Foreign Bodies/*epidemiology/*surgery Humans Laparoscopy/statistics & numerical data Length of Stay/statistics & numerical data Male Middle Aged Multivariate Analysis *Needs Assessment Prisoners/*statistics & numerical data Prisons/statistics & numerical data Retrospective Studies Risk Factors Young Adult Correctional institutions Endoscopy Foreign body ingestion Inmates Intentional ingestion of foreign objects Laparotomy Prisoners Swallowers LA - eng N1 - 1095-8673 Dalal, Poorvi P Otey, Andrew J McGonagle, Emily A Whitmill, Melissa L Levine, Edward J McKimmie, Ryan L Thomas, Alicia C Cook, Charles H Papadimos, Thomas J Reilley, Thomas E Bergese, Sergio D Steinberg, Steven M Stawicki, Stanislaw P A Evans, David C Journal Article United States J Surg Res. 2013 Sep;184(1):145-9. doi: 10.1016/j.jss.2013.04.078. Epub 2013 May 21. PY - 2013 SN - 0022-4804 SP - 145-9 ST - Intentional foreign object ingestions: need for endoscopy and surgery T2 - J Surg Res TI - Intentional foreign object ingestions: need for endoscopy and surgery VL - 184 ID - 138 ER - TY - JOUR AB - Introduction: Intentional ingestions of foreign objects (IIFO) are often associated with compulsive behavioral patterns and constitute a manifestation of a more profound, chronic underlying problem. This study was undertaken in order to better define clinical patterns of IIFO among predominantly incarcerated individuals admitted to a major academic institution. We sought to determine factors associated with IIFO-attributable hospital admission and procedural (both endoscopic and surgical) therapy. Methods: After obtaining IRB and state permission to conduct IIFO research in both incarcerated and non-incarcerated populations, study patients were identified by CPT codes. The following variables were collected: patient demographics; past medical history (including psychiatric conditions); characteristics related to recurrent IIFO events, hospital admission data, diagnostic testing, and endoscopic/surgical procedure information. Univariate and multivariate analyses were performed using SPSS 19. Results: 30 patients (26 male, mean age 25 years) with a total of 141 episodes of IIFO were identified. Nine patients (30%) had history of IIFO; 27 (90%) reported psychiatric diagnosis; and 10 (33%) had history of substance abuse. The median number of known IIFO's per patient was 3 (range 1-27, mean 4.7). The median number of days between episodes of IIFO was 33 (range 1-1563, mean 116). Mean therapeutic duration (i.e., emergency and/or hospital services) was 41 hours per episode. Most commonly ingested item types, alone or in combination, included plastic utensils (61/141), pens/pencils (57/141), toothbrushes and razor blades (24/141 each). The mean number of ingested items was 4.60 (median 2, range 1-68). Most ingested objects were >5 cm in largest dimension (97/141) and were identified on plain imaging. Endoscopy was performed in 98/141 IIFO instances, with failures to retrieve the ingested object in 20/98 (20%) cases. Fifteen instances (10.6%) required surgical intervention. On multivariate analyses, hospital admission was associated with elevated white blood cell count (OR 1.4, p<0.04) and post-gastric location of the ingested object (OR 22.9, p<0.034). The need for endoscopy was independently associated with ingestion of multiple objects (OR 4.6, p<0.03). Surgical therapy was significantly associated with elevated white blood cell count (OR 1.5, p<0.01) and with increasing number of ingested items (OR 1.086 per item, p<0.04). Endoscopy is associated with significantly lower odds of surgery (OR 0.16, p<0.01). Conclusion: Intentional ingestions of foreign objects continue to pose a significant human and economic burden. Most ingestions involve incarcerated individuals swallowing easily obtainable items of daily use. Prompt endoscopy may reduce admissions and prevent surgical interventions. Further investigation is warranted into methods of preventing recurrence of clinically significant IIFO and resource-appropriate triage of patients who present with IIFO. AD - P.P. Dalal, Department of Anesthesiology, Ohio State University, 410 West 10th Ave 411 Doan Hall, Columbus, OH, United States AU - Dalal, P. P. AU - Otey, A. J. AU - McGonagle, E. A. AU - Whitmill, M. L. AU - Thomas, A. C. AU - Cook, C. H. AU - Papadimos, T. J. AU - Reilley, T. E. AU - Bergese, S. D. AU - Steinberg, S. M. AU - Stawicki, S. P. AU - Evans, D. C. DB - Embase IS - 2 KW - plastic surgery human hospital admission surgeon endoscopy society university ingestion diagnosis patient multivariate analysis leukocyte count procedures imaging medical history hospital service Current Procedural Terminology emergency substance abuse psychiatric diagnosis toothbrush male population swallowing emergency health service therapy LA - English M3 - Conference Abstract N1 - L70973706 2013-01-25 PY - 2013 SN - 0022-4804 ST - Intentional foreign object ingestions: Determining factors associated with hospital admission, therapeutic endoscopy, and surgery T2 - Journal of Surgical Research TI - Intentional foreign object ingestions: Determining factors associated with hospital admission, therapeutic endoscopy, and surgery UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70973706&from=export VL - 179 ID - 489 ER - TY - JOUR AB - Cyanoacrylate (LOCTITE® 401™) is a fast-acting adhesive available nationwide, with medical and household uses. Most cases of cyanoacrylate exposure are accidental and occur in children less than 5 years old. Various routes of exposure have been reported including the dermal, oral, ocular, otic, nasal, and urethral routes; however, very few result in serious complication and mortality. Although a few cases of airway obstruction related to cyanoacrylate ingestion have been reported, intentional cyanoacrylate ingestion-induced gastrointestinal tract injury has scarcely been reported. In addition, there have been no reports of serious complications following intentional cyanoacrylate ingestion requiring surgical intervention. Herein, we report a case of intentional ingestion of cyanoacrylate in a 70-year-old man who required gastric wedge resection due to delayed gastric perforation. © 2017 Elsevier Inc. AD - Department of Emergency Medicine, Sanggye Paik Hospital, Inje University College of Medicine, 1342 Dongil-ro, Nowon-gu, Seoul, 139-707, South Korea Department of Radiology, Aerospace Medical Center, Republic of Korea Air Force, PO Box 335-21, 635 Danjae-ro, Namil-myeon, Cheongwon-gun, Chungcheongbuk-do 363-849, South Korea AU - Lee, S. H. AU - Yun, S. J. AU - Ryu, S. AU - Choi, S. W. AU - Kim, H. J. AU - Kang, T. K. AU - Oh, S. C. AU - Cho, S. J. DB - Scopus DO - 10.1016/j.ajem.2017.10.017 IS - 1 KW - Cyanoacrylate Gastric perforation Intentional ingestion Surgical treatment Toxicology M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 SP - 169.e5-169.e7 ST - Intentional cyanoacrylate ingestion: A rare cause of delayed gastric perforation requiring gastric wedge resection T2 - American Journal of Emergency Medicine TI - Intentional cyanoacrylate ingestion: A rare cause of delayed gastric perforation requiring gastric wedge resection UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85031128736&doi=10.1016%2fj.ajem.2017.10.017&partnerID=40&md5=d3ecc9b12f2e01b597eaf892aa1abf19 VL - 36 ID - 1103 ER - TY - JOUR AB - Stent implantation in the trachea, using polyurethane-coated metallic stents, reduces granulomatous reaction, demonstrating the possible treatment for severe form of tracheobronhomalacia in children. Methods: Materials and live experiments were performed using the newly invented metallic stent (LASER-cut stainless steel with a 100 micrometer coating of polyurethane). In the materials experiment, the relationship between the holding force and deformity was tested by a compressor. In the animal examination, coated stents were orally implanted into the trachea in five rabbits, while non-coated stents were implanted in another five rabbits. After three weeks observation, the inner diameter was measured by 3D computed tomography, and the number of granulation tissues was counted by broncho-fiberscope. Histological investigation followed in both groups. Results: In the materials experiment, new stents demonstrated a holding force similar to PALMAZ stents, and significantly higher holding force than self-expandable metallic stents (LUMINEX). (Figure1) In the animal experiment, no difference was found in the inner diameter of the coated and non-coated stent groups by 3D computed tomography (p=0.07). In the broncho-fiberscopy, no obvious granulation tissues were found in the trachea with coated stents and metallic frame seems covered in tracheal membrane while protrusion and significant bulging of granulation tissue recognized in non-coated stents. (Figure2A and B) The number of granulation tissues was higher in non-coated stents than in coated stents (p<0.01). (Figure2C) Histological investigation showed infiltration of inflammatory cells around the non-coated stents where epithelial structure was destroyed, while tracheal epithelia were preserved in the group of coated stents. Conclusions: The new polyurethane-coated metallic stent maintains enough holding force, and reduces histo-biological reaction to foreign bodies, suggesting new possibilities for use in treatment against tracheobronchomalacia in children. (Figure Presented). AD - H. Matsui, Nagano Children's Hospital, Nagano, Japan AU - Matsui, H. AU - Hiroma, T. AU - Ogiso, Y. AU - Hasegawa, H. DB - Embase KW - polyurethan stainless steel stent human tracheobronchomalacia child American society granulation tissue trachea computer assisted tomography metal stent Leporidae animal experiment laser fiberoscope trachea mucosa examination inflammatory cell fiberscope endoscopy membrane deformity foreign body granulomatous inflammation implantation LA - English M3 - Conference Abstract N1 - L71987080 2015-09-08 PY - 2012 SN - 1073-449X ST - Innovation of polyurethane coated stent for treatment against severe tracheobronchomalacia in children T2 - American Journal of Respiratory and Critical Care Medicine TI - Innovation of polyurethane coated stent for treatment against severe tracheobronchomalacia in children UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71987080&from=export http://www.atsjournals.org/doi/pdf/10.1164/ajrccm-conference.2012.185.1_MeetingAbstracts.A2491 VL - 185 ID - 510 ER - TY - JOUR AB - Patient complaining of front left cervical tumoral mass, painful to handling, with approximately three months evolution. Normal physical examination. Diagnostic Investigation: Normal thyroidal hormones, Normal full blood count and biochemistry, Normal chest X-Ray, Normal electrocardiography, Normal carcinoembrionary antigen, Thyroid cintilography:Diffuse goiter, Biopsy:Inflammatory response. Ultrasonographic report of the thyroid presented a linear echogenic structure surrounded by a hypoechoic area at the left lobe, compatible with foreign body and resultant inflammatory response. A fish bone was found after the patient was submitted to a left hand side lobectomy. AD - CARDIOLAB-ECOLAB, Rio de Janeiro, Brazil AU - Esteves, Irapuan DB - Scopus IS - Suppl 1 M3 - Article N1 - Export Date: 10 November 2020 PY - 1997 ST - Inner thyroid foreign body T2 - Ultrasound in Medicine and Biology TI - Inner thyroid foreign body UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030675018&partnerID=40&md5=a712219e2ce8f9bead5cd4a50b85241e VL - 23 ID - 1706 ER - TY - JOUR AB - Ingestion of multiple magnets poses a particular risk for various intraabdominal complications in children. We herein report a case of ingestion of multiple magnets, of which 3 were spontaneously expelled, and the remaining magnets were surgically removed. Since the total amount of ingestion was unknown upon presentation and the remaining intraabdominal magnets failed to pass after 24 h, emergency surgery was performed. Two magnets sandwiched the bowel walls and formed a jejunoileal fistula. There was no peritoneal contamination. We found that not all the ingested multiple magnets attracted each other, and multiple magnets could appear as single material on a plain radiograph. Confirming the exact count of ingested magnets is important; if the count is in doubt or two or more attachments are evident, prompt surgical intervention is warranted. © 2014 The Authors. Published by Elsevier Inc. All rights reserved. AD - S.-B. Moon, Department of Surgery, Kangwon National University Hospital, 156 Baekryoung-ro, Chuncheon 200-722, South Korea AU - Kim, Y. AU - Hong, J. AU - Moon, S. B. DB - Embase DO - 10.1016/j.epsc.2014.02.013 IS - 3 KW - article case report emergency surgery female foreign body gastroscopy human ileocecal valve infant ingestion intestine anastomosis intestine necrosis magnet priority journal small intestine LA - English M3 - Article N1 - L372748370 2014-04-11 2014-04-16 PY - 2014 SN - 2213-5766 SP - 130-132 ST - Ingestion of multiple magnets: The count does matter T2 - Journal of Pediatric Surgery Case Reports TI - Ingestion of multiple magnets: The count does matter UR - https://www.embase.com/search/results?subaction=viewrecord&id=L372748370&from=export http://dx.doi.org/10.1016/j.epsc.2014.02.013 VL - 2 ID - 456 ER - TY - JOUR AB - Introduction: Single foreign body ingestion is a scenario that gastroenterologists commonly see. However, multiple foreign body ingestion provides the endoscopist with significant challenges in management. We describe a case of ingestion of sixteen AA batteries that successfully passed the gastrointestinal track with conservative management after endoscopic attempt at removal. Case: 32-year-old female with history of schizoaffective disorder, presented with epigastric pain after ingested sixteen AA batteries in a suicide attempt. Patient underwent upper endoscopy with successful retrieval of 2 batteries. The other fourteen batteries had already passed beyond the ligament of Treitz. Surgical management was not indicated. Patient was kept NPO during the first two days, with intravenous fluid, proton-pump inhibitors and stool softener. Since abdominal pain improved, diet was advanced to clear liquids. During the hospital course, electrolytes, white blood cell count and kidney function remained stable. Daily abdominal x-rays were performed to monitor progression. After multiple failed oral therapy attempts, a nasogastric tube was placed to guarantee compliance with laxatives. After therapy with rapid colonoscopy preparation protocol, the patient successfully passed the remaining 14 batteries without complications at day 8. Discussion: Ingestion and/or insertion of foreign objects is seen in young, alcoholic or psychiatric patients. The incidence has not been established, but in a study between 2000 and 2006, in a urban hospital among 262 cases, 92% were intentional ingestion, 85% involved psychiatric patients, and 84% had history of prior ingestion. The dilemma is whether to allow the foreign body to pass spontaneous or to remove either endoscopically or surgically. Endoscopic approaches are recommended, especially for objects wider than 2.5 cm because they are less likely to pass the pylorus, although limited data exists to support this recommendation. Objects that fail to pass beyond the stomach by 3 to 4 weeks should be removed endoscopically to prevent obstruction. In this case evidence of progression throughout the gastrointestinal track was proved by daily abdominal x-ray without clinical deterioration. Successfully expulsion of the objects without further endoscopic intervention was possible. (Figure Presented). AD - J. Tejada, Brooklyn Hospital Center, Brooklyn, NY, United States AU - Tejada, J. AU - Campo, L. AU - Culliford, A. AU - Babich, J. P. DB - Embase DO - 10.1038/ajg.2015.270 KW - infusion fluid proton pump inhibitor electrolyte laxative human case report American college gastroenterology ingestion foreign body patient hospital mental patient therapy gastroenterologist abdominal pain schizoaffective psychosis epigastric pain female alcoholism surgery conservative treatment diet liquid ligament leukocyte count kidney function endoscopy nasogastric tube colonoscopy suicide attempt endoscopist pylorus stomach obstruction deterioration abdominal radiography LA - English M3 - Conference Abstract N1 - L72130566 2016-01-15 PY - 2015 SN - 0002-9270 SP - S216-S217 ST - Ingestion of multiple batteries: A case report T2 - American Journal of Gastroenterology TI - Ingestion of multiple batteries: A case report UR - https://www.embase.com/search/results?subaction=viewrecord&id=L72130566&from=export http://dx.doi.org/10.1038/ajg.2015.270 VL - 110 ID - 426 ER - TY - JOUR AB - INTRODUCTION: Ingestion of foreign bodies and their impaction at the lumen of the appendix is a very rare finding and only few cases have been reported all over the world. A variety of metallic foreign bodies when ingested may be lodged in the lumen of the appendix such as screws, bird shots, and needles. This is called in most literatures as foreign body appendicitis. CASE PRESENTATION: A 4-year-old boy with history of an accidental ingestion of a metallic nail presented to the emergency department one week later with right iliac fossa pain and one attack of vomiting. During abdominal examination there was tenderness and rebound tenderness at the right iliac fossa. Plain abdominal X-ray showed the metallic nail in the region of the right iliac fossa. Ultrasound examination was normal apart from tenderness of putting the probe on the right lilac fossa. The white blood cell counts were 14,000 cell per microliter. During surgery the nail was found to be impacted inside the lumen of the vermiform appendix causing inflammation of the appendix. Appendicectomy done and the patient discharged on the third day in a good general condition. CONCLUSION: Acute appendicitis may be caused by a variety of causes including ingested foreign bodies if impacted in its lumen. When the patient has signs of generalized peritonitis it is important to exclude bowel perforation. The surgery can be done by the open surgery or laparoscopically. AD - University of Duhok, College of Medicine, Department of Surgery, Duhok city, Kurdistan Region, Iraq. Electronic address: ayad.mohammed@uod.ac. Duhok Directorate of Health, Duhok Emergency Teaching Hospital, Duhok city, Kurdistan Region, Iraq. University of Duhok, College of Medicine, Department of Surgery, Duhok city, Kurdistan Region, Iraq. AN - 30981982 AU - Mohammed, A. A. AU - Ghazi, D. Y. AU - Arif, S. H. C2 - PMC6463815 DO - 10.1016/j.ijscr.2019.03.052 DP - NLM ET - 2019/04/15 KW - Appendicectomy Appendicitis Foreign body appendicitis Vermiform appendix LA - eng N1 - 2210-2612 Mohammed, Ayad Ahmad Ghazi, Dezhwar Yahya Arif, Sardar Hassan Journal Article Int J Surg Case Rep. 2019;57:201-204. doi: 10.1016/j.ijscr.2019.03.052. Epub 2019 Apr 5. PY - 2019 SN - 2210-2612 (Print) 2210-2612 SP - 201-204 ST - Ingested metallic foreign body impacted in the vermiform appendix presenting as acute appendicitis: Case report T2 - Int J Surg Case Rep TI - Ingested metallic foreign body impacted in the vermiform appendix presenting as acute appendicitis: Case report VL - 57 ID - 227 ER - TY - JOUR AB - A 37-year-old incarcerated man presented to the accident and emergency department following the deliberate ingestion of eight cylindrical batteries. He also admitted to inserting a razor blade wrapped in cling-film into his rectum; in addition, he sustained a self-inflicted laceration to his left antecubital fossa, using the metal casing from a battery. His medical history included a borderline and emotionally unstable personality disorder. He had ingested several batteries 12 months previously and required an emergency laparotomy to retrieve them. On the present admission, as there was no clinical evidence of small bowel obstruction, he was treated conservatively with serial radiographs. Following conservative management, the batteries failed to progress through the gastrointestinal tract, hence a laparotomy was performed and all the batteries were extricated. This paper discusses the management and associated sequelae of patients presenting following the intentional ingestion of a battery. Copyright © 2015 BMJ Publishing Group. AD - Department of Surgery, Milton Keynes University Hospital, Buckinghamshire, Milton Keynes, United Kingdom AU - Dunphy, L. AU - Maatouk, M. AU - Raja, M. AU - O'Hara, R. C7 - 1503 DB - Scopus DO - 10.1136/bcr-2014-208922 M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2015 ST - Ingested cylindrical batteries in an incarcerated male: A caustic tale! T2 - BMJ Case Reports TI - Ingested cylindrical batteries in an incarcerated male: A caustic tale! UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84945960128&doi=10.1136%2fbcr-2014-208922&partnerID=40&md5=4450156e21618b4fd686e1f2a5d11e61 VL - 2015 ID - 1219 ER - TY - JOUR AB - Background: Experimental knowledge about mesh behavior at the esophageal hiatus is rare, but such information is essential in order to find a safe and effective method of mesh reinforcement. This study aimed to investigate the influence of mesh structure on the biological behavior of polypropylene prostheses placed at the hiatus. Materials and Methods: Twenty-four pigs in three groups of eight underwent implantation of heavyweight small-porous (HW-SP), heavyweight large-porous (HW-LP), or lightweight large-porous (LW-LP) circular polypropylene mesh at the hiatus. Eight weeks later, the meshes were explanted. Macroscopic analysis was performed evaluating mesh deformation, adhesions, and position relative to the hiatal margin. Histological analysis comprised evaluation of foreign body reaction and tissue integration by mononuclear cell count and immunostaining of Ki-67, collagen type I, and collagen type III. Results: No mesh-related complications occurred. Mesh shrinkage was observed within all groups and was the lowest for HW-LP, higher for HW-SP, and highest for LW-LP (13.8% versus 19.5% versus 25.5%; P<.001). The adhesion score was highest for HW-SP, lower for HW-LP, and lowest for LW-LP (11.0 versus 8.0 versus 6.0; P<.001). The collagen type I/III ratio was higher for HW-SP compared with HW-LP and LW-LP (3.1 versus 2.2 versus 1.8; P=.014). Conclusions: Heavyweight polypropylene meshes may be advantageous for application at the hiatus. They provide a solid fixation of the esophagogastric junction by adhesions, which may contribute to a reduction of hernia recurrence. In heavyweight meshes, the large-porous structure is associated with superior form stability, and small-porous meshes are superior with regard to solidity of tissue integration, which may prevent mesh migration. © 2014, Mary Ann Liebert, Inc. AD - Department of General, Abdominal and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany Department of Pathology, University of Heidelberg, Heidelberg, Germany Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany AU - Senft, J. AU - Gehrig, T. AU - Lasitschka, F. AU - Linke, G. R. AU - Shevchenko, M. AU - Bruckner, T. AU - Kenngott, H. G. AU - Fischer, L. AU - Müller-Stich, B. P. DB - Scopus DO - 10.1089/lap.2013.0588 IS - 6 M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2014 SP - 383-390 ST - Influence of weight and structure on biological behavior of polypropylene mesh prostheses placed at the esophageal hiatus T2 - Journal of Laparoendoscopic and Advanced Surgical Techniques TI - Influence of weight and structure on biological behavior of polypropylene mesh prostheses placed at the esophageal hiatus UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84902343597&doi=10.1089%2flap.2013.0588&partnerID=40&md5=3226b4759ad26d898ae9839cd4ca0e74 VL - 24 ID - 1260 ER - TY - JOUR AB - Background: Supplementary polyglecaprone 25 (Monocryl) monofilaments were added to a lightweight pure monofilament polypropylene mesh (PP mesh) to improve intraoperative handling (PP+M mesh). This study was designed to evaluate the influence of this additional supplementation on the biocompatibility in a rodent animal model. Methods: Two mesh materials, a composite mesh (PP+M) and the pure polypropylene variant (PP), were compared after subcutaneous implantation in a standardized rat model. Histological analysis of the inflammatory response was performed after 28, 56 and 84 days of implantation. Material absorption, inflammatory tissue reaction, fibrosis and granuloma formation were investigated, as well as the percentage of proliferating and apoptotic cells at the interface. Results: Both mesh materials showed a slight foreign body reaction involving mainly macrophages and foreign body giant cells. Total absorption of the Monocryl filaments of the PP+M mesh occurred between 56 and 84 days of implantation. Both the inflammatory and the fibrotic reaction were decreased (n.s.) in the PP+M mesh group compared to the pure PP mesh. Whereas the percentage of proliferating cells showed no significant difference, the rate of apoptotic cells was significantly decreased in the PP+M mesh group over the whole implantation period. Conclusion: Compared to the pure polypropylene mesh, our data confirm that the use of a polypropylene mesh supplemented with absorbable Monocryl filaments is feasible without additional short-term mesh-related complications in the experimental model or negative side effects on biocompatibility. © Springer-Verlag 2005. AD - Department of Surgery, Technical University of Aachen, Pauwelsstr. 30, 52074 Aachen, Germany German Centre of Excellence for Biomaterial and Implant Pathology, Technical University of Aachen, Pauwelsstr. 30, 52074 Aachen, Germany IZKF BIOMAT, Technical University of Aachen, Pauwelsstr. 30, 52074 Aachen, Germany Medical Clinic II, Technical University of Aachen, Pauwelsstr. 30, 52074 Aachen, Germany Institute of Pathology, Technical University of Aachen, Pauwelsstr. 30, 52074 Aachen, Germany AU - Junge, K. AU - Rosch, R. AU - Krones, C. J. AU - Klinge, U. AU - Mertens, P. R. AU - Lynen, P. AU - Schumpelick, V. AU - Klosterhalfen, B. DB - Scopus DO - 10.1007/s10029-004-0315-5 IS - 3 KW - Biocompatibility Mesh Polyglecaprone 25 Polypropylene M3 - Article N1 - Cited By :70 Export Date: 10 November 2020 PY - 2005 SP - 212-217 ST - Influence of polyglecaprone 25 (Monocryl) supplementation on the biocompatibility of a polypropylene mesh for hernia repair T2 - Hernia TI - Influence of polyglecaprone 25 (Monocryl) supplementation on the biocompatibility of a polypropylene mesh for hernia repair UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-32044451580&doi=10.1007%2fs10029-004-0315-5&partnerID=40&md5=e68364d66f5da1af6ea203ddf272f35a VL - 9 ID - 1599 ER - TY - JOUR AB - Alterations of the extracellular matrix (ECM) with its major component collagen are increasingly discussed as possible risk factors implicated in the development of abdominal-wall herniation. Because of the widespread use of alloplastic meshes for the surgical repair of hernias, an animal study was performed to analyze the influence of various mesh materials on the quantity and quality of collagen deposition. In 60 male Sprague-Dawley rats an abdominal replacement was performed using three different kinds of mesh materials: polyester (PE), a pure polypropylene (PP), and a composite mesh made of polypropylene and polyglactin (PG). A simple fascia suture repair served as control. The count of fibroblasts, the collagen/protein ratio, the type I/III collagen ratio, and the ex-pression of basic fibroblast growth factor (b-FGF) at the interface were analyzed after 7, 21, and 90 days. The ratio of collagen to overall protein (μg/mg) showed significant differences comparing different mesh materials (sham controls 38.44 ± 16.33 μg/mg, PE 68.5= 23.8 μg/mg, PP 101.6 ± 32.3 μg/mg, PG 49.6 μ 11.6 μg/mg at day 90). The ratio of collagen type I/III increased over time in all groups. However, 90 days after mesh implantation the ratio was always significantly lowered compared to the controls. No significant difference was found comparing different mesh materials. The alteration of the scar composition is closely connected to an increased b-FGF expression. b-FGF and count of fibroblasts highly correlated (r = .95) and showed significant elevated levels compared to simple suture repair. The results of our study strongly support the notion that wound healing is affected by mesh implantation. The quality of the ECM deposition as determined by collagen type I/III ratio is impaired in general, whereas the quantity of ECM deposition is markedly influenced by the kind of mesh material. AD - Department of Surgery, Technical University of Aachen, Pauwelsstraße 30, 52057 Aachen, Germany Institute of Pathology, Technical University of Aachen, Aachen, Germany Department of Internal Medicine, Technical University of Aachen, Aachen, Germany AU - Junge, K. AU - Klinge, U. AU - Klosterhalfen, B. AU - Mertens, P. R. AU - Rosch, R. AU - Schachtrupp, A. AU - Ulmer, F. AU - Schumpelick, V. DB - Scopus DO - 10.1080/08941930290086137 IS - 6 KW - b-FGF Biomaterial Collagen Mesh Wound healing M3 - Article N1 - Cited By :58 Export Date: 10 November 2020 PY - 2002 SP - 319-328 ST - Influence of mesh materials on collagen deposition in a rat model T2 - Journal of Investigative Surgery TI - Influence of mesh materials on collagen deposition in a rat model UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036873471&doi=10.1080%2f08941930290086137&partnerID=40&md5=ae36c0b6b7d1d6bdb55560ffa2d4307f VL - 15 ID - 1657 ER - TY - JOUR AB - This study explored the vulnerability of the ductus deferens due to mesh induced inflammation and shrinkage after hernia repair in the rodent model. Two commonly used types of hernioplastic implants (Prolene™ and Vypro II™) were surgically wrapped around the ductus deferentes on both sides in 20 juvenile and 20 adult Sprague-Dawley rats. Twenty male rats underwent sham surgeries as controls. After 3 months, each male was mated with 2-3 adult females, which were subsequently sacrificed and oocytes or embryos were flushed and counted. Histochemical investigations of the implants and the ductus recovered surgically 4 weeks after implantation (one side) and after the fertility test (second side) were conducted. All groups exhibited 1-3 males with decreased or restricted fertility but there was no difference between groups. Histochemical analysis of the implants and the ductus recovered 4 weeks and 4 months after implantation revealed some sperm granulomes due to lesions of the spermatic cord caused by the implant in the Prolene™ group. There was no inflammatory reaction in the mucosa or blockage of the spermatic cord visible. Both types of hernioplastic implants tested in this investigation do not give an indication of a negative influence on male fertility in juvenile or adult rats. © 2006 Wiley Periodicals, Inc. AD - Institute of Laboratory Animal Science, Research Center Biomodels, University of Veterinary Medicine, Vienna, Austria Department of Surgery, General Hospital, Krems, Austria AU - Kolbe, T. AU - Lechner, W. DB - Scopus DO - 10.1002/jbm.b.30681 IS - 2 KW - Hernia repair Hernioplastic implant Male fertility Rat M3 - Article N1 - Cited By :10 Export Date: 10 November 2020 PY - 2007 SP - 435-440 ST - Influence of hernioplastic implants on male fertility in rats T2 - Journal of Biomedical Materials Research - Part B Applied Biomaterials TI - Influence of hernioplastic implants on male fertility in rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-34247608649&doi=10.1002%2fjbm.b.30681&partnerID=40&md5=fe8e12fc2a67f5e762040984f44f16c1 VL - 81 ID - 1565 ER - TY - JOUR AB - Objective: Wear-induced aseptic loosening has been accepted as one of the main reasons for failure of total hip arthroplasty. Ceramic wear debris is generated following prosthesis implantation and plays an important part in the upregulation of inflammatory factors in total hip arthroplasty. The present study investigates the influence of ceramic debris on osteoblasts and inflammatory factors. Methods: Ceramic debris was prepared by mechanical grinding of an aluminum femoral head and added to cultures of MC3T3-E subclone 14 cells at different concentrations (i.e. 0, 5, 10, and 15 μg/mL). Cell proliferation was evaluated using a Cell Counting Kit (CCK-8), and cell differentiation was assessed by mRNA expression of alkaline phosphatase (ALP), osteocalcin (OCN), and osteopontin (OPN). In addition, cell bio-mineralization was evaluated through alizarin red S staining, and release of tumor necrosis factor alpha (TNF-α), interleukin-1 beta (IL-1β), and interleukin-6 (IL-6) was measured through enzyme-linked immunosorbent assays (ELISA). Furthermore, mRNA expression of Smad1, Smad4, and Smad5 and protein expression of phosphorylated Smad1, Smad4, and Smad5 were measured by reverse transcriptase polymerase chain reaction (RT-PCR) and western blotting. Results: The ceramic debris had irregular shapes and sizes, and analysis of the size distribution using a particle size analyzer indicated that approximately 90% of the ceramic debris was smaller than 3.2 μm (2.0 ± 0.4 μm), which is considered clinically relevant. The results for mRNA expression of ALP, OCN, and OPN and alizarin red S staining indicated that cell differentiation and bio-mineralization were significantly inhibited by the presence of ceramic debris at all tested concentrations (P < 0.05, and the values decreased gradually with the increase of ceramic debris concentration), but the results of the CCK-8 assay showed that cell proliferation was not significantly affected (P > 0.05; there was no significant difference between the groups at 1, 3, and 5 days). In addition, the results of ELISA, RT-PCR, and western blotting demonstrated that ceramic debris significantly promoted the release of inflammatory factors, including TNF-α, IL-β, and IL-6 (P < 0.05, and the values increased gradually with the increase of ceramic debris concentration), and also greatly reduced the mRNA expression of Smad1, Smad4, and Smad5 (the values decreased gradually with the increase of ceramic debris concentration) as well as protein expression of phosphorylated Smad1, Smad4, and Smad5. Conclusion: Ceramic debris may affect differentiation and bio-mineralization of MC3T3-E subclone 14 cells through the bone morphogenetic protein/Smad signaling pathway. © 2019 The Authors. Orthopaedic Surgery published by Chinese Orthopaedic Association and John Wiley & Sons Australia, Ltd AD - Department of Orthopaedic Surgery, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China Department of Orthopaedic Surgery, Nanjing 81th Hospital of PLA, Nanjing, China Department of Orthopaedic Surgery, Xiamen 174th Hospital of PLA, Xiamen, China Department of Emergency Surgery, Zhengzhou Orthopaedic Hospital, Zhengzhou, China AU - Sun, G. J. AU - Yang, S. F. AU - Ti, Y. F. AU - Guo, G. D. AU - Fan, G. T. AU - Chen, F. R. AU - Xu, S. G. AU - Zhao, J. N. DB - Scopus DO - 10.1111/os.12496 IS - 5 KW - BMP/Smads Osteoblast Signaling pathway Total hip arthroplasty Wear debris M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2019 SP - 770-776 ST - Influence of Ceramic Debris on Osteoblast Behaviors: An In Vivo Study T2 - Orthopaedic Surgery TI - Influence of Ceramic Debris on Osteoblast Behaviors: An In Vivo Study UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071315431&doi=10.1111%2fos.12496&partnerID=40&md5=1069db70c4bd0c6a88c214802cdca663 VL - 11 ID - 994 ER - TY - JOUR AB - The therapeutic use of ventricular assist devices (VADs) for end-stage heart failure (HF) patients who are ineligible for transplant has increased steadily in the last decade. In parallel, improvements in VAD design have reduced device size, cost, and device-related complications. These complications include infection and thrombosis which share underpinning contribution from the inflammatory response and remain common risks from VAD implantation. An added and underappreciated difficulty in designing a VAD that supports heart function and AIDS the repair of damaged myocardium is that different types of HF are accompanied by different inflammatory profiles that can affect the response to the implanted device. Circulating inflammatory markers and changes in leukocyte phenotypes receive much attention as biomarkers for mortality and disease progression. However, they are seldom used to monitor progress during and outcomes from VAD therapy or during the design phase for new devices. Even the partial reversal of heart damage associated with heart failure is a desirable outcome from VAD use. Therefore, improved understanding of the interplay between VADs and the recipient's inflammatory response would potentially increase their uptake, improve patient lives, and fuel research related to other blood-contacting medical devices. Here we provide a review of what is currently known about inflammation in heart failure and how this inflammatory profile is altered in heart failure patients receiving VAD therapy. © 2007 - 2018 Frontiers Media S.A. AD - Swansea University Medical School, Swansea, United Kingdom Calon Cardio-Technology Ltd, Institute of Life Science, Swansea, United Kingdom Scandinavian Real Heart AB, Västeras, Sweden Department of Cardiology, Morriston Hospital, Abertawe Bro Morgannwg University Health Board, Swansea, United Kingdom AU - Radley, G. AU - Pieper, I. L. AU - Ali, S. AU - Bhatti, F. AU - Thornton, C. A. C7 - 2651 DB - Scopus DO - 10.3389/fimmu.2018.02651 IS - NOV KW - cytokines heart failure inflammation leukocytes ventricular assist devices M3 - Review N1 - Cited By :6 Export Date: 10 November 2020 PY - 2018 ST - The inflammatory response to ventricular assist devices T2 - Frontiers in Immunology TI - The inflammatory response to ventricular assist devices UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85057402770&doi=10.3389%2ffimmu.2018.02651&partnerID=40&md5=357c7c8f44125aab6cc3141423bbc944 VL - 9 ID - 1054 ER - TY - JOUR AB - A thorough understanding of the mechanisms involved in the host reaction to alginate-poly-l-lysine microcapsules (HRM) is important to design methods for the evaluation, selection, and development of biocompatible biomaterials and microcapsules or treatments to control this reaction. The objective of this study was to identify those immune cells and cytokines involved in the pathogenesis of the HRM. The total and differential cell counts were evaluated, and the mRNA expression of TNF-α, IL-1β, IL-6 and TGF-β1 was measured in peritoneal washings at 3, 17, 48, 96 and 168 h after saline or microcapsule injections. Neutrophil number and IL-1β and IL-6 m-RNA expression presented an early transient increase, with no differences between saline and microcapsule injections, suggesting a reaction to the procedure. Macrophages, lymphocytes and TNF-α were significantly more activated over a longer period of time, after microcapsule implantation than saline injection. They are likely involved in transforming the reaction into a chronic inflammatory process. TGF-β1 and IL-1β presented a late (day 7) significant increase after microcapsule but not saline injections. They are likely involved in transforming the reaction into a fibrogenic process. These results suggest that macrophages, lymphocytes, TNF-α, IL-1β and TGF-β1 play a role in the pathogenesis of the HRM. © 2004 Elsevier Ltd. All rights reserved. AD - Université de Montréal, Centre de Recherche Guy-Bernier, Hôpital Maisonneuve-Rosemont, 5415 boulevard de l'Assomption, Montréal, Que. H1T 2M4, Canada Département de Biochimie, Hôpital Maisonneuve-Rosemont, 5415 boulevard de l'Assomption, Montréal, Que. H1T 2M4, Canada AU - Robitaille, R. AU - Dusseault, J. AU - Henley, N. AU - Desbiens, K. AU - Labrecque, N. AU - Hallé, J. P. DB - Scopus DO - 10.1016/j.biomaterials.2004.10.028 IS - 19 KW - Biocompatibility Cytokine Interleukin Macrophage Microcapsule TGF M3 - Article N1 - Cited By :60 Export Date: 10 November 2020 PY - 2005 SP - 4119-4127 ST - Inflammatory response to peritoneal implantation of alginate-poly-L-lysine microcapsules T2 - Biomaterials TI - Inflammatory response to peritoneal implantation of alginate-poly-L-lysine microcapsules UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-12344310263&doi=10.1016%2fj.biomaterials.2004.10.028&partnerID=40&md5=f3943e8cf0d37503576a3343ee7124fa VL - 26 ID - 1605 ER - TY - JOUR AB - Despite widespread use of the gelatin-sealed knitted Dacron prosthesis (GDP) in clinical practice owing to its zero porosity, the biological impacts of this graft are still controversial. We conducted a randomized controlled study on 50 patients undergoing abdominal aortic aneurysm repair to evaluate the inflammatory reaction to GDP (n = 25) and unsealed knitted Dacron prostheses (UDP, n = 25). There were no significant differences in the mean age, size of the aneurysm, operative time, blood loss, or transfusion requirements between the GDP and UDP groups. During the first 7 postoperative days (PODs), slight fever and leukocytosis were noticed in both groups. Significant differences in maximum body temperature, leukocyte count, and plasma C-reactive protein concentration were observed between the GDP and VDP groups on POD 14: 37.2 ± 0.5°C vs 36.9 ± 0.3°C (P = 0.019), 8,151 ± 1,788/μl vs 6,914 ± 1,501/μl (P = 0.015), and 32.6 ± 27.5 mg/l vs 19.0 ± 15.8 mg/l (P = 0.048), respectively. By POD 21, however, there were no detectable differences in these variables. Thus, we concluded that GDP caused an inflammatory reaction in the 2nd week after implantation, but ultimately there were no significant differences from UDP by the 3rd week. AD - First Department of Surgery, Kumamoto Univ. School of Medicine, 1-1-1 Honjo, Kumamoto City, Kumamoto 860, Japan AU - Utoh, J. AU - Miyauchi, Y. AU - Goto, H. AU - Obayashi, H. AU - Hirata, T. DB - Scopus DO - 10.1007/BF00311584 IS - 4 KW - biocompatibility C-reactive protein gelatin-sealed Dacron prosthesis M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 1996 SP - 258-261 ST - Inflammatory reactions after vascular prosthesis implantation: A comparison of gelatin-sealed and unsealed dacron prostheses T2 - Surgery Today TI - Inflammatory reactions after vascular prosthesis implantation: A comparison of gelatin-sealed and unsealed dacron prostheses UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029978273&doi=10.1007%2fBF00311584&partnerID=40&md5=4e0e893223f402cf00b95f7dab881900 VL - 26 ID - 1716 ER - TY - JOUR AB - Purpose: The use prosthetic materials for the surgical repair of abdominal wall defects has become almost standard practice. This study was designed to assess the expression of different growth factors (VEGF/TGF-β1) and macrophages during the early host tissue incorporation of several polypropylene lightweight (PP-LW) - including one partially absorbable - and heavyweight (PP-HW) prosthetic meshes. Methods: Ventral defects were created in the anterior abdominal wall of New Zealand rabbits and repaired by fixing PP-LW meshes of different pore size and a low porosity PP-HW mesh to the edges of the defect. Following killing 14 days after implant, specimens were taken to examine TGF-β1/VEGF gene and protein expression by qRT-PCR and immunohistochemistry. The macrophage response was also assessed. Results: All the materials showed good host tissue incorporation, with a more severe inflammatory reaction and greater numbers of macrophages recorded in the partially absorbable LW implants. Relative amounts of VEGF mRNA were significantly lower for the LW partially absorbable implants compared with the remaining LW meshes. Protein expression of VEGF showed undetectable or minimum staining in the different groups. TGF-β1 mRNA levels were also lower in the partially absorbable group compared with one of PP-LW type of mesh. Gene expression patterns were consistent with the TGF-β1 protein levels detected. Conclusions: The results suggest that VEGF and TGF-β1 expression were independent of mesh pore size. The expression of both growth factors and the macrophage response were correlated with the presence of biodegradable material in the mesh. The presence of absorbable material in the LW mesh gave rise to a more intense inflammatory reaction and the reduced synthesis of growth factors known to contribute to neotissue maturation. © 2012 Springer-Verlag. AD - Department of Medical Specialities, University of Alcalá, Alcalá de Henares, Madrid, Spain Department of Surgery, Faculty of Medicine, University of Alcalá Ctra, Madrid-Barcelona Km 33, 600, 28871 Alcalá de Henares, Madrid, Spain Networking Research Center on Biomaterials, Bioengineering and Nanomedicine (CIBER-BBN), Madrid, Spain AU - Pascual, G. AU - Rodríguez, M. AU - Sotomayor, S. AU - Pérez-Köhler, B. AU - Bellón, J. M. DB - Scopus DO - 10.1007/s10029-012-0945-y IS - 6 KW - Abdominal meshes Foreign body reaction Growth factor Wound healing M3 - Article N1 - Cited By :21 Export Date: 10 November 2020 PY - 2012 SP - 697-707 ST - Inflammatory reaction and neotissue maturation in the early host tissue incorporation of polypropylene prostheses T2 - Hernia TI - Inflammatory reaction and neotissue maturation in the early host tissue incorporation of polypropylene prostheses UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84878428492&doi=10.1007%2fs10029-012-0945-y&partnerID=40&md5=12d42017d219b6571ac4fabf16f73cfa VL - 16 ID - 1351 ER - TY - JOUR AB - A 35-year-old woman presented with a history of vague epigastric pain which lasted for one day. She had no other gastrointestinal symptoms and had an unremarkable past history and physical examination. An ultrasound scan abdomen showed a 3x3.5 cm mass in the left lobe of liver. A CT scan showed an abnormal hypodense lesion with mild enhancement in the arterial phase, with a central calcification. Complete blood count, liver function test and alpha-fetoprotein were normal. A left lateral segmentectomy was performed after adequate pre-operative assessment. The specimen contained a 3 cm long fishbone. The post-operative period was uneventful. Histopathological examination revealed chronic non-specific inflammation with fibrosis. Inflammatory pseudotumor of liver is a rare benign tumor with uncertain etiopathogenesis. Suggested etiologies include a septic or a viral origin and it can occur after migration of sharp objects, including migrated fishbone. Inflammatory pseudotumor of liver can be a diagnostic challenge and may end up in major resection. © 2013 Hellenic Society of Gastroenterology. AD - U. P. Srinivasan, Department of Surgical Gastroenterology, 6/2, Indra Nagar 29th Cross Road, Adyar, Chennai, Tamilnadu 600 020, India AU - Srinivasan, U. P. AU - Duraisamy, A. B. AU - Ilango, S. AU - Rathinasamy, A. AU - Chandramohan, S. M. DB - Embase IS - 1 KW - adult article case report computer assisted tomography contrast enhancement echography epigastric pain female foreign body histopathology human human tissue hepatic inflammatory pseudotumor laparoscopy laparotomy liver fibrosis liver surgery pseudotumor LA - English M3 - Article N1 - L368033958 2013-01-09 2013-01-21 PY - 2013 SN - 1108-7471 1792-7463 SP - 84-86 ST - Inflammatory pseudotumor of liver secondary to migrated fishbone - A rare cause with an unusual presentation T2 - Annals of Gastroenterology TI - Inflammatory pseudotumor of liver secondary to migrated fishbone - A rare cause with an unusual presentation UR - https://www.embase.com/search/results?subaction=viewrecord&id=L368033958&from=export http://www.annalsgastro.gr/index.php/annalsgastro/article/view/1192/979 VL - 26 ID - 490 ER - TY - JOUR AB - Surgical glove powders have been implicated in serious postoperative foreign body reactions due to contamination of the operative field. Inflammatory responses to glove lubricants or mold release agents have to date been studied to a lesser extent in ocular tissues than other body tissues, although powder contamination of intraocular lenses, with severe postoperative anterior chamber inflammatory responses, have been reported. The object of this study was to grade and quantitate the inflammatory response of surgical glove lubricants, namely Biosorb, Keoflo, calcium carbonate and Hydrocote (a hydrogel polymer film used in powderless gloves), as introduced into the posterior chamber on New Zealand white rabbits. In a double masked GLP study, a total of 150 eyes were evaluated. For each of the four test samples, a dose response curve was obtained at 10 micrograms (Keoflo only), 125 micrograms, 250 micrograms, 500 micrograms, 1000 micrograms, and 1500 micrograms. Study parameters were the quantitation of inflammatory cells in the aqueous and vitreous, and ocular irritation and inflammation, as graded by the rabbit inflammation score system, at 0 and 48 hours post-injection. A Wilcoxen signed-rank test used to evaluate statistical significance (p < 0.05). A test vitreal cell count was less that 50 cells/mm3 and the overall mean clinical response was less than 2.0. This study established that Keoflo at all concentrations 10 micrograms-1000 micrograms), and Biosorb at concentrations greater than 1000 micrograms were inflammatory. Calcium carbonate and Hydrocote were non-inflammatory at concentration of 125 micrograms-1500 micrograms. The unoperated, sham, vehicle and Ocugel controls were all non-inflammatory. The positive Zymozan A controls were defined as inflammatory. In conclusion, no glove powder is totally safe, even small amounts of glove powder (10 micrograms) can elicit an inflammatory immune response. If all glove powder averages 700mg/pair, this should be removed prior to contact with a patients tissue. Powder-free gloves and greatly reduce the potential inflammatory risk associated with powdered gloves. AD - Department of Ophthalmology, Kangnam St. Mary's Hospital, Catholic University of Korea, Medical College, Seoul, South Korea AU - Park, H. S. AU - Kim, M. S. DB - Scopus DO - 10.3341/kjo.1997.11.1.51 IS - 1 M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 1997 SP - 51-59 ST - The inflammatory potential of surgical glove lubricants: Biosorb, Keoflo, calcium carbonate and Hydrocote after intravitreal injection T2 - Korean journal of ophthalmology : KJO TI - The inflammatory potential of surgical glove lubricants: Biosorb, Keoflo, calcium carbonate and Hydrocote after intravitreal injection UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031157286&doi=10.3341%2fkjo.1997.11.1.51&partnerID=40&md5=50fbb10f192e433b6666fa29fc9ab2e6 VL - 11 ID - 1711 ER - TY - JOUR AB - The inflammatory and fibrous responses in a subcutaneous rat model were evaluated around degradable polyurethane urea (PUUR; Artelon®), with titanium and tissue culture polystyrene (PS) discs having different surface chemical properties but similar surface topography. Cytokines, viability, cellular response, differentiation of cells and fibrous capsule formation and vascularization was investigated after 1, 7 and 21 days of implantation. The exudates retrieved from the pockets were analysed with respect to the total cell numbers, the proportions of cell types, the differentiation of monocytes/macrophages (ED1, ED2), the DNA content and the viability (LD, Trypan blue). Tumour necrosis factor alpha ((h)TNF-α) and interleukin-10 ((h)IL-10) were quantified by ELISA. The number of blood vessels, blood vessel luminal area, blood vessel distribution and the fibrous capsule thickness were analysed. The highest number of cells in the exudates around all implants was detected during the early phase of healing (1-7 days). The proportion of ED2-positive cells in the exudates increased from 2-8% at 1 day to 43-56% at 21 days. The levels of TNF-α were low with a decrease at 7 days. After 21 days high amounts of IL-10 in the exudates were detected, in particular around PUUR. This study shows that the transition from inflammation to repair (1-21 days) around PUUR, Ti and PS materials was characterized by a decrease in inflammatory cell influx, an increasing proportion of ED2-expressing macrophages, a biphasic TNF-α secretion, an increase of IL-10 and a fibrous capsule formation similar to all materials tested. © VSP 2006. AD - Institute of Surgical Sciences, The Sahlgrenska Academy, Göteborg University, SE 405 30 Göteborg, Sweden Artimplant AB, Hulda Mellgrensgata 5, V. Frölunda, Sweden AU - Gretzer, C. AU - Emanuelsson, L. AU - Liljensten, E. AU - Thomsen, P. DB - Scopus DO - 10.1163/156856206777346340 IS - 6 KW - Biocompatibility Cytokine Poly(urethane urea) Polystyrene Titanium Wound healing M3 - Article N1 - Cited By :103 Export Date: 10 November 2020 PY - 2006 SP - 669-687 ST - The inflammatory cell influx and cytokines changes during transition from acute inflammation to fibrous repair around implanted materials T2 - Journal of Biomaterials Science, Polymer Edition TI - The inflammatory cell influx and cytokines changes during transition from acute inflammation to fibrous repair around implanted materials UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33746078519&doi=10.1163%2f156856206777346340&partnerID=40&md5=5028f61aa8bc19a5f1694dc60e0805a0 VL - 17 ID - 1583 ER - TY - JOUR AB - PURPOSE: To assess the safety and tissue response of a polymethyl methacrylate (PMMA) glaucoma drainage device (GDD) in the rabbit eye. METHODS: Specially constructed PMMA GDD devices were implanted into rabbit eyes and evaluated histopathologically following euthanasia on days 5, 30, and 60 after implantation surgery. Hematoxylin-eosin, Masson's trichrome, and periodic acid-Schiff were used to stain tissue specimens dissected from the surgical site. Inflammatory cell count and capsule thickness measurements were performed. RESULTS: Three rabbits were sacrificed on day 5, 3 on day 30, and 4 on day 60. Macrophage and lymphocyte counts increased from day 5 to day 30 then decreased (P = 0.0000) with greater counts seen in the superior regions. At day 30, a fibrous capsule had formed around the plate area. Fibroblast counts increased significantly between day 5 to day 30 and again to day 60 (P = 0.001) with greatest numbers anteriorly. The inferior capsule thickness at day 60 was 243 µm (standard deviation, 120; 95% confidence interval: 53-433). The superior capsule thickness was 388 µm (standard deviation, 136; 95% confidence interval: 172-604). No adverse reactions were seen. CONCLUSIONS: Histopathologically, the inflammatory response toward this PMMA glaucoma drainage device was comparable to other reported GDDs. No accentuated response or adverse event was seen suggesting that PMMA may be useful as a GDD material. TRANSLATIONAL RELEVANCE: An affordable, locally built GDD is needed in Indonesia because of the high prevalence of severe glaucoma. This rabbit study is a significant step toward justifying the use of PMMA as a GDD material. PMMA is cheap and easily manufactured and sterilized in developing economies. AD - Ophthalmology Department, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia. Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Faculty of Veterinary, Institute Pertanian Bogor, Bogor, West Java, Indonesia. Ophthalmology Department, University of Western Australia, Nedlands, WA, Australia. AN - 32714646 AU - Asrory, V. D. O. AU - Sitompul, R. AU - Artini, W. AU - Estuningsih, S. AU - Noviana, D. AU - Morgan, W. H. C2 - PMC7352041 DA - Feb 18 DO - 10.1167/tvst.9.3.20 DP - NLM ET - 2020/07/28 IS - 3 KW - foreign body reaction glaucoma drainage device inflammatory reaction polymethyl methacrylate Estuningsih, None D. Noviana, None W.H. Morgan, None LA - eng N1 - 2164-2591 Asrory, Virna D Oktariana Sitompul, Ratna Artini, Widya Estuningsih, Sri Noviana, Deni Morgan, William H Journal Article Transl Vis Sci Technol. 2020 Feb 18;9(3):20. doi: 10.1167/tvst.9.3.20. PY - 2020 SN - 2164-2591 (Print) 2164-2591 SP - 20 ST - The Inflammatory and Foreign Body Reaction of Polymethyl Methacrylate Glaucoma Drainage Device in the Rabbit Eye T2 - Transl Vis Sci Technol TI - The Inflammatory and Foreign Body Reaction of Polymethyl Methacrylate Glaucoma Drainage Device in the Rabbit Eye VL - 9 ID - 258 ER - TY - JOUR AB - Inferior vena cava filter placement is an important method for managing deep venous thrombosis of the lower extremities and has a high risk of pulmonary embolism. Filter migration is rare but potentially fatal. We describe a case of migration of an inferior vena cava filter to the left internal iliac vein. The filter perforated the internal iliac vein, resulting in hemorrhagic shock, and was removed with open surgery. To our knowledge, this is the first reported case of migration of an inferior vena cava filter to an internal iliac vein. © 2019 AD - Vascular Surgery Department of Xuanwu Hospital of Capital Medical University, Beijing, China Vascular Surgery Department of Chengde Medical College, Chengde, China AU - Chen, L. AU - Zhang, J. AU - Yang, Z. DB - Scopus DO - 10.1016/j.avsg.2019.12.012 M3 - Article N1 - Export Date: 10 November 2020 PY - 2020 SP - 289.e13-289.e16 ST - Inferior Vena Cava Filter Migration to the Left Internal Iliac Vein T2 - Annals of Vascular Surgery TI - Inferior Vena Cava Filter Migration to the Left Internal Iliac Vein UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85079556370&doi=10.1016%2fj.avsg.2019.12.012&partnerID=40&md5=c8e5152b3b35a9cd80b6b21de4436395 VL - 65 ID - 967 ER - TY - JOUR AB - Infective endocarditis is an endovascular microbial infection of cardiovascular structures, including large intrathoracic vessels and intracardiac foreign bodies. In case of periannular tissue involvement results could be catastrophic. Periannular abscess rupture leads to aorto-cavitary fistula formation with subsequent intracardiac shunting which furthermore overloads the heart progressively leading to heart failure. This complication must be timely recognized and surgically treated. Transesophageal echocardiography presents highly accurate imaging tool capable of detecting endocarditis and its complications even in the absence of positive blood cultures. Staphylococcus aureus, Streptococcus viridians groups A, C and G and Enterococcus species are the most common microorganisms that cause infective endocarditis. Several surgical techniques have been proposed for treating native valve endocarditis including valve repair or replacement, drainage of abscess cavities, the excision of necrotic tissue and the closure of aorto-cavitary fistula. We present a case of native valve endocarditis caused by Enterococcus spp. with a partial disruption of right coronary valve, two large periannular abscesses and aorto-cavitary fistula to the right ventricle. AD - Clinic for Cardiovascular Surgery, Institute of Cardiovascular Diseases of Vojvodina, Novi Sad, Serbia Clinic for Cardiology, Institute of Cardiovascular Diseases of Vojvodina, Novi Sad, Serbia AU - Velicki, L. AU - Susak, S. AU - Srdanovic, I. AU - Kovacevic, M. DB - Scopus IS - 6 KW - Aortic valve Heart failure Infective endocarditis Surgery M3 - Article N1 - Export Date: 10 November 2020 PY - 2010 SP - 261-265 ST - Infective endocarditis of native aortic valve: Destruction of leaflet with an aorto-cavitary fistula to the right ventricle T2 - Chirurgia TI - Infective endocarditis of native aortic valve: Destruction of leaflet with an aorto-cavitary fistula to the right ventricle UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79955023077&partnerID=40&md5=517c25f9462f7e9b48224fa971e40c5f VL - 23 ID - 1442 ER - TY - JOUR AB - Objective: The optimal surgical and antimicrobial treatment for intracranial infections after neurosurgery is unknown. We investigated the clinical, laboratory, and microbiological characteristics of intracranial infections after neurosurgery. In addition, treatment outcome in patients treated according to a standardized algorithm was evaluated. Methods: Consecutive patients with extradural, intradural, and device-related infections after cranial neurosurgery were included prospectively. A standardized antimicrobial and surgical treatment regimen was applied. The probability of infection-free survival was estimated by using the Kaplan–Meier survival method. Survival curves between groups were compared by using log-rank Mantel–Cox test. Results: Of 103 infections, 58 (56%) were extradural, 33 (32%) intradural, and 12 (12%) device-associated. Foreign material was involved in 98 infections (95%), including 78 bone flaps or fixation devices, 41 duraplasties, 17 external drains, and 15 functional devices. The median duration from primary surgery until infection diagnosis was 33 days (range, 6–1132 days). In total, 69 infections (67%) were monomicrobial, 26 (25%) polymicrobial, and 8 (8%) culture-negative. Ninety of 103 patients (90%) underwent surgical intervention, of whom foreign material was retained in 24 (23%). The probability of infection-free survival was 87% after 12 months (95% confidence interval 77%–93%). Nonadequate antimicrobial therapy was associated with treatment failure (5% vs. 70%, P < 0.001), which remained significant in the multiple logistic regression model (P = 0.01). Conclusions: Most (95%) intracranial infections were associated with foreign material and required surgical intervention and biofilm-active treatment. Via a standardized treatment approach, the infection-free survival after 12 months was good (87%), independent of the infection site or type of micro-organism. © 2018 Elsevier Inc. AD - Center for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany Department of Neurosurgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Beriln and Berlin Institute of Health, Berlin, Germany AU - Renz, N. AU - Özdirik, B. AU - Finger, T. AU - Vajkoczy, P. AU - Trampuz, A. DB - Scopus DO - 10.1016/j.wneu.2018.05.017 KW - Craniotomy Neurosurgery Outcome Surgical-site infection Treatment M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2018 SP - e491-e499 ST - Infections After Cranial Neurosurgery: Prospective Cohort of 103 Episodes Treated According to a Standardized Algorithm T2 - World Neurosurgery TI - Infections After Cranial Neurosurgery: Prospective Cohort of 103 Episodes Treated According to a Standardized Algorithm UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047645862&doi=10.1016%2fj.wneu.2018.05.017&partnerID=40&md5=ef59a272941fa50d21a65ab9491458de VL - 116 ID - 1068 ER - TY - JOUR AB - Coronary angiography and percutaneous coronary intervention (PCI) are frequently performed procedures in the UK and the developed world, with the radial artery becoming the preferred route of access. A chronically retained macroscopic fragment of radial artery introducer sheath is a very rare complication that has not, to our knowledge, been reported. We report the case of a 62-year-old woman who underwent PCI and developed a persisting infected sinus and abscess at the cannulation site despite multiple courses of antibiotics. Surgical exploration of the forearm recovered a foreign body that was found in the brachioradialis muscle and resembled a fragment of hydrophilic sheath. In conclusion, this case highlights that it is possible to leave macroscopic fragments of hydrophilic sheaths in situ. This is likely to be encountered during difficult access, especially during arterial spasm, and it is advised that the sheath and any other vascular access device is thoroughly inspected following removal. © 2019 BMJ Publishing Group Limited. No commercial re-use. See rights and permissions. Published by BMJ. AD - Department of Trauma and Orthopaedic Surgery, Gateshead Health NHS Foundation Trust, Gateshead, United Kingdom Department of Cardiology, Gateshead Health NHS Foundation Trust, Gateshead, United Kingdom AU - Ghazala, C. G. AU - Marrow, B. A. AU - Kearney, D. AU - Harrison, J. W. K. C7 - 227136 DB - Scopus DO - 10.1136/bcr-2018-227136 IS - 3 KW - cardiovascular medicine interventional cardiology interventional radiology orthopaedic and trauma surgery orthopaedics M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 ST - Infected chronic sinus secondary to a retained fragment of radial artery introducer sheath following percutaneous coronary intervention (PCI) T2 - BMJ Case Reports TI - Infected chronic sinus secondary to a retained fragment of radial artery introducer sheath following percutaneous coronary intervention (PCI) UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85062863538&doi=10.1136%2fbcr-2018-227136&partnerID=40&md5=aaf56865c47ea9eaa38fc0efefbacc61 VL - 12 ID - 1038 ER - TY - JOUR AB - Introduction Pulmonary Neuroendocrine tumors have been categorized into high, intermediate and low grade. The distinction between low grade typical carcinoid from atypical carcinoid depends on mitotic count and presence of punctate necrosis. Case presentation The patient is a 60 year old female with past medical history of diabetes mellitus, hyperlipidemia, gastrointestinal reflux disease and cervical myelopathy. An incidental right upper lobe nodule was discovered during hospitalization for post-total knee arthroplasty sepsis. Follow-up CT and PET scans demonstrated size stability with mild hypermetabolic activity. The tumor was excised by a robotic thoracoscopic right upper lobectomy and mediastinal lymph node dissection. A lobulated, tan-yellow, well demarcated firm mass, measuring 1.2 × 1 × 1 cm was grossly identified. Microscopically, the well circumscribed mass demonstrated near complete infarct-like central necrosis with a peripheral viable cellular rim consisting of nests of tumor cells that stained positively with TTF-1, Synaptophysin, Chromogranin, and CD56; and was negative for calcitonin and monoclonal CEA. The mitotic figure count was negligible and met the WHO criteria for typical carcinoid. The proliferative index (Ki-67) was slightly high at 9.29%. Discussion The unusual central necrosis seen in the tumor and the relatively high proliferative index created a pathological diagnostic dilemma discussed in this report. © 2017 The Authors AD - Department of Pathology, MetroHealth Medical Center, Cleveland, OH, United States Department of Cardiothoracic surgery, MetroHealth Medical Center, Cleveland, OH, United States AU - Jassim, S. H. AU - Temes, R. T. AU - Tomashefski, J., Jr. DB - Scopus DO - 10.1016/j.ehpc.2017.03.003 KW - Carcinoid Lung Neuroendocrine tumors M3 - Article N1 - Export Date: 10 November 2020 PY - 2017 SP - 65-68 ST - Infarcted neuroendocrine tumor following endobronchial ultrasound guided fine needle aspiration of a pulmonary nodule: Typical versus atypical carcinoid a pathological diagnostic dilemma T2 - Human Pathology: Case Reports TI - Infarcted neuroendocrine tumor following endobronchial ultrasound guided fine needle aspiration of a pulmonary nodule: Typical versus atypical carcinoid a pathological diagnostic dilemma UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85026216241&doi=10.1016%2fj.ehpc.2017.03.003&partnerID=40&md5=6b289e43c1c70affe2d4045db1cc6a06 VL - 8 ID - 1134 ER - TY - JOUR AB - The spleen is the largest lymphatic organ that acts as a site for filtration of foreign particles from the blood, erythropoiesis and hematopoiesis. Splenectomy represents the first line of treatment for spontaneous splenic rupture, abscesses, cysts, tumours. It is also used to control hereditary, autoimmune, and myeloproliferative disorders alternatively. Numerous diseases have been indicated for surgery in non-traumatic spleen diseases such as non-traumatic spleen rupture, immune thrombocytopenic purpura (ITP), haemolytic anaemias, Felty's syndrome, Hodgkin's and non-Hodgkin's lymphoma among others. This result because the spleen is the most affected lymphoid organ following its overactivity that occurs during sequestration of dead or disrupted RBCs and lymphocytes. Abdominal pain is one of the major manifestations of splenomegaly, and can also designate other associated complications such as liver cirrhosis or bacterial endocarditis. As a secondary lymphoid organ, the spleen is more often an organ for lymphomas. Although splenectomy is a curative alternative in a few diseases, it is a complementary means of treating several other diseases. Splenectomy is a salvage therapy used when other therapeutic alternatives fail. Despite its indication in numerous diseases, controversies are still inbound of its use. © 2019 Danilo Coco, Silvana Leanza. AD - Ospedali Riuniti Marche Nord, Pesaro, Italy Ospedale Augusto Murri-Fermo, Fermo, Italy Carlo Urbani Hospital, Jesi, Italy AU - Coco, D. AU - Leanza, S. DB - Scopus DO - 10.3889/oamjms.2019.568 IS - 17 KW - Non-traumatic spleen disease Spleen Surgery M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 2958-2960 ST - Indications for surgery in non-traumatic spleen disease T2 - Open Access Macedonian Journal of Medical Sciences TI - Indications for surgery in non-traumatic spleen disease UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076020059&doi=10.3889%2foamjms.2019.568&partnerID=40&md5=876aaaf25e166a197594d3c68b9af908 VL - 7 ID - 995 ER - TY - JOUR AB - Communication and collaboration in patient care settings is vital for promoting the best possible patient outcomes. The counting of sponges, sharps, and instruments, and the surgical time out before the start of any surgical procedure are opportunities for the surgical team to address patient safety risks. Personnel in the surgical services department at St Luke's Episcopal Hospital, Houston, Texas, implemented the use of a hanging, magnetic, dry-erase board that includes the elements of a time out (eg, patient name and identifiers, procedure, site, allergies) and provides a means to document countable items. The board promotes team awareness of this time out and count information at all times during a procedure. Specific magnets on the count board identify items intentionally packed inside the patient to remind the team of the location of these items when the count is reconciled at the end of the procedure. In addition, a process of obtaining an radiograph of items similar to any missing items assists radiologists in identifying the location of retained surgical items. As a result of implementing both changes, our ability to locate missing items has significantly increased. AD - St Luke's Episcopal Hospital, O'Quinn Medical Towers, Houston, TX, USA. AN - 20888944 AU - Edel, E. M. DA - Oct DO - 10.1016/j.aorn.2010.03.013 DP - NLM ET - 2010/10/05 IS - 4 KW - *Communication Humans Medical Errors/*prevention & control Safety Management Texas LA - eng N1 - 1878-0369 Edel, Elizabeth Morell Journal Article United States AORN J. 2010 Oct;92(4):420-4. doi: 10.1016/j.aorn.2010.03.013. PY - 2010 SN - 0001-2092 SP - 420-4 ST - Increasing patient safety and surgical team communication by using a count/time out board T2 - Aorn j TI - Increasing patient safety and surgical team communication by using a count/time out board VL - 92 ID - 103 ER - TY - JOUR AB - Aseptic loosening is an increasing problem in total hip replacement (THR). Chronic inflammatory reaction against implant wear particle results in collageno- and osteolysis, leading to loosening of the implant. Cytokines are known to play a major role in this particular inflammatory process. The aim of the present study was to examine interleukin-8 (IL-8) in the synovial-like interface membrane (SLIM) and pseudocapsular tissue of THRs and to compare it to normal knee synovial membrane. Eleven patients suffering from aseptically loosened THRs were included. All the SLIM and pseudocapsular tissue samples were obtained during revision operations. Ten control samples of normal synovium were collected per arthroscopy from the superior recessus of the knee. For immunohistochemical IL-8 detection, polyclonal mouse anti-human immunoglobulin (Ig)G1 IL-8-primary antibody was used with the alkaline phosphatase anti-alkaline phosphatase (APAAP) method. Results were quantitated using the Vidas image analysis system. The highest count levels (mean ± SEM) were detected in SLIM tissue (386 ± 82 cells/mm2). The difference was statistically significant compared with pseudocapsular tissue (193 ± 36 cells/mm2) and control samples (18 ± 5 cells/mm2). Count levels in control tissue were on average 5% of the SLIM tissues values. The present study determines for the first time the cellular origin of IL-8 in aseptically loosened THRs and also quantitates the IL-8-producing cells in the periprosthetic tissue. The results reveal a high rise in IL-8 concentration in SLIM and in synovial tissues. This finding moves us one step forward in solving the complex network of multiple factors affecting loosening of hip implants. AD - Dept. Orthopaedics and Traumatology, Helsinki University Central Hospital, Topeliuksenkatu 5, FIN-00260 Helsinki, Finland Institute of Biomedicine, Department of Anatomy, University of Helsinki, Helsinki, Finland Dept. Orthopaedics and Traumatology, Kuopio University Central Hospital, Kuopio, Finland National Agency for Medicine, Medical Devices Centre, Helsinki, Finland Finnish Academy, Institute of Biomedicine, University of Helsinki, Helsinki, Finland AU - Lassus, J. AU - Waris, V. AU - Xu, J. W. AU - Li, T. F. AU - Hao, J. AU - Nietosvaara, Y. AU - Santavirta, S. AU - Konttinen, Y. T. DB - Scopus DO - 10.1007/s004020050475 IS - 5-6 KW - Aseptic loosening Immunohistochemistry Interleukin-8 Total hip replacement M3 - Article N1 - Cited By :52 Export Date: 10 November 2020 PY - 2000 SP - 328-332 ST - Increased interleukin-8 (IL-8) expression is related to aseptic loosening of total hip replacement T2 - Archives of Orthopaedic and Trauma Surgery TI - Increased interleukin-8 (IL-8) expression is related to aseptic loosening of total hip replacement UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034060196&doi=10.1007%2fs004020050475&partnerID=40&md5=c8b1cb3b2e6a31e1ac38115ed2d75bce VL - 120 ID - 1676 ER - TY - JOUR AB - Polydimethylsiloxane (PDMS) is the most common type of silicone polymer for the fabrication of implantable medical devices. Because of its inherent hydrophobic nature, the PDMS surface does not readily promote cellular adhesion, which leads to diverse clinical issues. Previously, we reported a simple water vapor plasma treatment of PDMS surfaces that resulted in stable long-term wettability and excellent in vitro cell compatibility. In this work, we report investigation of the in vivo local responses to PDMS implants treated by water vapor plasma using a subcutaneous rat model. The local tissue responses were assessed after 2 and 4 weeks of implantation by means of macroscopic and histomorphometric analysis. After 2 weeks of implantation, the plasma-treated implants elicited the formation of fibrous tissue capsules that were significantly thinner, more adherent, and vascularized than the control counterparts. The improved cell adhesion was correlated with an increased amount of cells attached to the implant surface after retrieval. There was no difference in the inflammatory response between untreated and treated samples. This study provides a rational approach to optimize the long-term performance of silicone implants, which is likely to have a significant impact in clinical applications demanding enhanced tissue integration of the implants. © 2012 Wiley Periodicals, Inc. AD - Department of Health Science and Technology, Aalborg University, Fredrik Bajers Vej 7, DK-9220 Aalborg, Denmark Department of Physics and Nanotechnology, Aalborg University, Skjernvej 4A, DK-9220 Aalborg, Denmark Neurodan A/S, Sofiendalsvej 85, DK-9200, Aalborg SV, Denmark AU - Jensen, C. AU - Gurevich, L. AU - Patriciu, A. AU - Struijk, J. J. AU - Zachar, V. AU - Pennisi, C. P. DB - Scopus DO - 10.1002/jbm.a.34284 IS - 12 KW - Cell adhesion Foreign body response Polydimethylsiloxane Surface modification Water vapor plasma M3 - Article N1 - Cited By :14 Export Date: 10 November 2020 PY - 2012 SP - 3400-3407 ST - Increased connective tissue attachment to silicone implants by a water vapor plasma treatment T2 - Journal of Biomedical Materials Research - Part A TI - Increased connective tissue attachment to silicone implants by a water vapor plasma treatment UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84869087060&doi=10.1002%2fjbm.a.34284&partnerID=40&md5=906d133d5d6a5d347f50fb7c7487ea80 VL - 100 A ID - 1397 ER - TY - JOUR AB - Ensuring that patients remain free of unintended retained foreign bodies is a primary responsibility of perioperative nurses and surgical technologists. However, these incidents continue to occur despite hospital policies and AORN recommended practice guidelines for their prevention. To provide insight into how incorrect surgical counts occur, researchers conducted a qualitative analysis of the tasks and challenges faced by perioperative nurses and surgical technologists in an academic medical center and a community hospital. Using hermeneutic phenomenological methodology, we identified bad behavior, general chaos, and communication difficulties as problems associated with incorrect surgical counts. As point-of-care providers, perioperative RNs are well poised to identify problematic areas and design systems and processes that protect patients. Perioperative RNs should consider using red rules or a code of conduct as tools for improving the manual counting process. These strategies could be developed in the shared governance council or a perioperative staff-led committee to ensure adherence to AORN standards. AD - Martha Jefferson Hospital, Charlottesville, VA, USA. AN - 20888943 AU - Rowlands, A. AU - Steeves, R. DA - Oct DO - 10.1016/j.aorn.2010.01.019 DP - NLM ET - 2010/10/05 IS - 4 KW - Humans *Medical Errors Nursing Staff, Hospital Perioperative Nursing LA - eng N1 - 1878-0369 Rowlands, Aletha Steeves, Richard Journal Article United States AORN J. 2010 Oct;92(4):410-9. doi: 10.1016/j.aorn.2010.01.019. PY - 2010 SN - 0001-2092 SP - 410-9 ST - Incorrect surgical counts: a qualitative analysis T2 - Aorn j TI - Incorrect surgical counts: a qualitative analysis VL - 92 ID - 102 ER - TY - JOUR AN - 3634594 AU - Murphy, E. K. DA - Apr DO - 10.1016/s0001-2092(07)68139-3 DP - NLM ET - 1986/04/01 IS - 4 KW - Adult Aged Female Foreign Bodies/*etiology *General Surgery Humans Male Malpractice/*legislation & jurisprudence Operating Room Nursing/legislation & jurisprudence Pregnancy *Surgical Equipment LA - eng N1 - Murphy, E K Case Reports Journal Article United States AORN J. 1986 Apr;43(4):918-24. doi: 10.1016/s0001-2092(07)68139-3. PY - 1986 SN - 0001-2092 (Print) 0001-2092 SP - 918-24 ST - Incorrect counts; surgeon's negligence does not absolve nurses from liability T2 - Aorn j TI - Incorrect counts; surgeon's negligence does not absolve nurses from liability VL - 43 ID - 12 ER - TY - JOUR AB - Hamartomas of the spleen are rare benign tumourlike lesions that tend to be asymptomatic incidental findings. Splenic hamartomas with tumour-like extramedullary erythropoiesis are extremely rare. A 70-year-old male patient with dyspnoea and a nodular intrapulmonary lesion morphologically verified by CT underwent fibre bronchoscopy, which showed a pea-shaped foreign body that was retrieved without complication. As a secondary finding, the CT showed a splenic lesion of about 8 cmin size. An MR study showed an expansive process in the center of the spleen. The patient was completely free of clinical symptoms. Because of the unknown nature and the high risk for spontaneous rupture of the lesion, a splenectomy was performed. The histological analyses revealed tumour-like extramedullary erythropoiesis of the spleen. The patient was discharged in good condition ten days postoperatively. A hamartoma of the spleen with extramedullary tumor-like erythropoiesis should be considered in the differential diagnosis of a splenic lesion. © 2011 Springer-Verlag. AD - Division of General Surgery, Department of Surgery, Medical University of Graz, Auenbruggerplatz 29, 8036 Graz, Austria Division of Thoracic and Hyperbaric Surgery, Department of Surgery, Medical University of Graz, Graz, Austria Department of Pathology, Medical University of Graz, Graz, Austria AU - Dolcet, C. AU - Kornprat, P. AU - Lindenmann, J. AU - Beham-Schmid, C. AU - Mischinger, H. J. DB - Scopus DO - 10.1007/s10354-011-0019-2 IS - 15-16 KW - Extramedullary erythropoiesis Hamartoma Spleen Splenadenoma Splenoma M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2011 SP - 394-397 ST - Incidental finding of a splenic hamartoma with tumour-like extramedullary erythropoiesis T2 - Wiener Medizinische Wochenschrift TI - Incidental finding of a splenic hamartoma with tumour-like extramedullary erythropoiesis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-83455163855&doi=10.1007%2fs10354-011-0019-2&partnerID=40&md5=f9068e579204b6891eb3ec369603f7f6 VL - 161 ID - 1409 ER - TY - JOUR AB - BACKGROUND: The term gossypiboma refers to a sponge that has been forgotten in the surgical field. It is the most common retained surgical item, and constitutes a continuing problem for surgical safety. We performed a hospital-based study to examine their incidence, root cause, and outcomes, as an effort toward improving prevention. METHODS: This retrospective study covered 10 years (2006-2015) and included surgically confirmed cases of abdominal gossypibomas occurring after 45,011 abdominal and gynaecological operations in 2 public hospitals in Lome (Togo). Age, diagnosis, initial surgical procedure, evidence of textile count, and data related to the revision procedure were collected for descriptive analysis. RESULTS: Fifteen cases of gossypibomas (11 women and 4 men) were recorded. The mean age of the patients was 27 (range 21-55) years. Initial procedures were gynaecological in 11 patients and 5 cases involved an emergency surgery. Evidence of sponge counting was found in 6cases. Gossypiboma was an incidental finding in 1 patient. The average time to onset of symptoms after the initial procedure was 2 months. The gossypiboma was removed within 7 days to 4 years after the initial procedure. Postoperative complications included enterocutaneous fistula in 2 patients, incisional hernia in 2 patients, and wound sepsis in 1 patient. Death occurred in 2 patients (13.3%). CONCLUSIONS: Although rare, the incidence of gossypibomas is still unacceptably high and reveals failures regarding patient safety standards. The associated morbidity and mortality are significant, yet can be reduced by an early diagnosis in the immediate postoperative period. A systematic methodical count of sponges is the cornerstone of prevention, and introducing surgical safety protocols, such as the WHO Safe Surgery Saves Lives checklist, can enhance effectiveness. There is a crucial need for safety-focused policies, which may include a never event reporting system, elaboration of prevention strategies, interventions, and evaluation. AD - Department of Surgery, Teaching Hospital of Sylvanus Olympio, Lomé, Togo. Visceral surgeon at Sylvanus Olympio Teaching Hospital, 198 rue de la santé, P.O Box 57, Lomé, Togo. Department of Radiology, Teaching Hospital of Sylvanus Olympio, Lomé, Togo. General surgery, Lomé Commune Regional Hospital, Lomé, Togo. AN - 29090018 AU - Tchangai, B. AU - Tchaou, M. AU - Kassegne, I. AU - Simlawo, K. C2 - PMC5657063 DO - 10.1186/s13037-017-0140-2 DP - NLM ET - 2017/11/02 KW - CT scan Complications Foreign body reaction Gossypiboma Laparotomy Prevention requirements by the Hospital Ethics Committees and was approved. CONSENT FOR PUBLICATION: Written informed consent for publication of their clinical details and/or clinical Images was obtained from the patients. A copy of the consent form are available for review by the Editor of this journal. COMPETING INTERESTS: All authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. LA - eng N1 - 1754-9493 Tchangai, Boyodi Orcid: 0000-0003-2280-8767 Tchaou, Mazamaesso Kassegne, Iroukora Simlawo, Kpatekana Journal Article Patient Saf Surg. 2017 Oct 26;11:25. doi: 10.1186/s13037-017-0140-2. eCollection 2017. PY - 2017 SN - 1754-9493 (Print) 1754-9493 SP - 25 ST - Incidence, root cause, and outcomes of unintentionally retained intraabdominal surgical sponges: a retrospective case series from two hospitals in Togo T2 - Patient Saf Surg TI - Incidence, root cause, and outcomes of unintentionally retained intraabdominal surgical sponges: a retrospective case series from two hospitals in Togo VL - 11 ID - 200 ER - TY - JOUR AB - Background: Aero-digestive tract foreign bodies (FB) are commonly seen either in children or in elderly age group. Various methods have been described in literature for their removal. In our study we aimed to analyze the incidence, risk factors, site, clinical presentations, different modalities used to extract tracheobronchial and esophageal foreign bodies in patients presented with FB aspiration or ingestion to the Emergency, Cardiothoracic Surgery, ENT and Chest disease departments in Alexandria Main University Hospital during the period between 1-11-2014 to 1-11-2015. Methods: A review of ninety patients with alleged FB aspiration and one hundred patients with alleged FB ingestion underwent complete history taking including personal data, date of presentation, date of aspiration or ingestion, circumstances of aspiration or ingestion, and past history of any previous medical or surgical conditions. Clinical assessment included vital signs and complete physical examination & investigations e.g.; complete blood count, random blood sugar, coagulation profile, renal function tests and liver function tests. Imaging including plain X-ray, CT scan, ultrasound, and virtual bronchoscopy were done. Some patients underwent rigid esophagoscopy/bronchoscopy under general anesthesia, based on clinical and radiological evidence. Some patients underwent surgical interventions. Results: Regarding FB aspiration, we found that sex difference was statistically significant in teenagers and adult group; females were found to be more commonly affected than males. Also most of cases of pin aspiration were teenagers (>10–20 years) and adults (>20 years). We noticed that right main bronchus FB was found more frequently in children below 10 years. Rigid bronchoscopic extraction of the FBs was the most common modality of extraction seen in 70 patients (77.8%). Regarding FB ingestion we noticed that females were commonly affected than males, coins were the most commonly ingested FB; and upper oesophageal sphincter (UES) was the commonest site of FB entrapment. Conclusions: FBs in the aero-digestive tract constituted a constant hazard in all age groups especially in children and the elderly, which demanded immediate action and management. AD - S.W. Hammad, Department of Emergency Medicine, Faculty of Medicine, University of Alexandria, Egypt AU - Elhamady, H. A. E. AU - Ramadan, A. E. M. AU - Gaafar, A. H. AU - Baess, A. I. AU - Hammad, S. W. DB - Embase DO - 10.1016/j.jescts.2017.05.002 IS - 2 KW - antibiotic agent atropine beta adrenergic receptor stimulating agent corticosteroid halothane hydrocortisone oxygen suxamethonium adolescent adult aged article blood cell count blood clotting bradycardia bronchoscope bronchoscopy bronchospasm catheter removal child clinical assessment echography esophageal bougie esophagoscopy esophagus foreign body esophagus perforation esophagus stenosis female fiberoscope fluoroscopy Foley balloon catheter forceps foreign body aspiration glucose blood level human incidence ingestion kidney function test liver function test major clinical study male mediastinitis medical nebulizer percussion physical examination postural drainage radiography risk factor sex difference thorax radiography upper esophagus sphincter vital sign x-ray computed tomography LA - English M3 - Article N1 - L616378617 2017-05-30 2017-07-04 PY - 2017 SN - 1110-578X SP - 154-162 ST - Incidence, patterns and different modalities in extraction of aero-digestive tract foreign bodies in patients attending alexandria main university hospital T2 - Journal of the Egyptian Society of Cardio-Thoracic Surgery TI - Incidence, patterns and different modalities in extraction of aero-digestive tract foreign bodies in patients attending alexandria main university hospital UR - https://www.embase.com/search/results?subaction=viewrecord&id=L616378617&from=export http://dx.doi.org/10.1016/j.jescts.2017.05.002 VL - 25 ID - 374 ER - TY - JOUR AB - Recent advances in chemotherapy and radiation therapy in the treatment of malignant bone tumours as well as the consistent increase of revision arthroplasties have been followed by an increased use of megaprostheses. These large foreign bodies make infection a common and feared complication. Infection rates of 3 - 31% have been reported (average approx. 15%), often in conjunction with risk factors, e.g. the anatomic region (pelvis implants in particular), implant alloy, and underlying reason for implantation of a megaprosthesis. Apart from the basic principles of septic revision arthroplasty, special patient and implant factors have to be considered in infected megaprosthesis, which we have summarised in our paper (e.g. life expectancy, implant design, spacers and external stabilisation). This article further analyses the current literature available for these cases and summarises outcome after treatment of periprosthetic infections. © 2012 Wichtig Editore. AD - Clinic for Orthopaedics and Sports Orthopaedics, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany AU - Pilge, H. AU - Gradl, G. AU - von Eisenhart-Rothe, R. AU - Gollwitzer, H. DB - Scopus DO - 10.5301/HIP.2012.9576 IS - SUPPL.8 KW - Infection Megaprosthesis Modular arthroplasty Periprosthetic infection Revision arthroplasty Tumor arthroplasty M3 - Article N1 - Cited By :19 Export Date: 10 November 2020 PY - 2012 SP - S83-S90 ST - Incidence and outcome after infection of megaprostheses T2 - HIP International TI - Incidence and outcome after infection of megaprostheses UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84873726558&doi=10.5301%2fHIP.2012.9576&partnerID=40&md5=893580c2870afa27c17810a0490c96eb VL - 22 ID - 1365 ER - TY - JOUR AB - BACKGROUND: Incidence of retained foreign objects (RFOs) after operations is unknown, as many can go unrecognized for years. We reviewed the incidence and characteristics of surgical RFO events at a tertiary care institution during 4 years. STUDY DESIGN: All RFO events, near misses and actual, reported on an adverse event line during 2003 to 2006 were reviewed. RESULTS: During 2003 to 2006, there were 191,168 operations performed, with 68 reported events resulting in a potential RFO defect rate of 0.356/1,000 patients. After review, 34 patients had no RFOs (near misses) and 34 were actual RFOs, resulting in a true RFO defect rate of 0.178/1,000 operations or approximately 1:5,500 operations. In the near-miss patient, needles were miscounted 76% of the time. In the 34 actual RFO patients, items retained were 23 sponges (68%), 7 miscellaneous other items (20%), 3 needles (9%), and 1 instrument (3%). The 34 actual RFOs occurred in incidents where the count had been reported as correct in 21 patients (62%). In 18 patients where an RFO was eventually discovered, intraoperative imaging detected only 12 objects (67%). In operations involving a body cavity, our practice is to obtain a high-resolution x-ray survey film, in a dedicated x-ray suite, before entering the recovery room. Twenty RFOs were identified from survey films and all occurred in patients with correct counts. No RFOs occurred during emergency or high blood-loss procedures and none resulted in demonstrable clinical harm. Two patients left the hospital with an RFO. Twenty-two patients (64.8%) underwent reoperation, with 1 object not removed, 6 (17.6%) retrieved without operation, and 6 (17.6%) where the clinical decision was not to remove. CONCLUSIONS: RFOs at an institution that routinely performs postprocedure x-rays indicate that RFOs can occur more frequently than expected from the literature. The majority occur in patients with correct counts. Relying on counting as the primary mechanism to avoid RFOs is unreliable, and investigating new technologies designed to achieve reliable counts is warranted. AD - Department of Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. cima.robert@mayo.edu AN - 18589366 AU - Cima, R. R. AU - Kollengode, A. AU - Garnatz, J. AU - Storsveen, A. AU - Weisbrod, C. AU - Deschamps, C. DA - Jul DO - 10.1016/j.jamcollsurg.2007.12.047 DP - NLM ET - 2008/07/01 IS - 1 KW - Foreign Bodies/diagnostic imaging/*epidemiology Humans Needles Radiography Reoperation Retrospective Studies Surgical Instruments Surgical Sponges LA - eng N1 - 1879-1190 Cima, Robert R Kollengode, Anantha Garnatz, Janice Storsveen, Amy Weisbrod, Cheryl Deschamps, Claude Journal Article United States J Am Coll Surg. 2008 Jul;207(1):80-7. doi: 10.1016/j.jamcollsurg.2007.12.047. Epub 2008 May 23. PY - 2008 SN - 1072-7515 SP - 80-7 ST - Incidence and characteristics of potential and actual retained foreign object events in surgical patients T2 - J Am Coll Surg TI - Incidence and characteristics of potential and actual retained foreign object events in surgical patients VL - 207 ID - 78 ER - TY - JOUR AB - A case report of a remarkably long-term penile incarceration by a foreign body and its management and outcome are examined. © 1973. AD - Department of Surgery, Division of Urology, West Virginia University Medical Center, Morgantown, WV, United States AU - Stuppler, S. A. AU - Walker, J. G. AU - Kandzari, S. J. AU - Milam, D. F. DB - Scopus DO - 10.1016/0090-4295(73)90472-X IS - 3 M3 - Article N1 - Cited By :14 Export Date: 10 November 2020 PY - 1973 SP - 308-309 ST - Incarceration of penis by foreign body T2 - Urology TI - Incarceration of penis by foreign body UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015665454&doi=10.1016%2f0090-4295%2873%2990472-X&partnerID=40&md5=f2a6dadd32b31cf77900b844a408718a VL - 2 ID - 1782 ER - TY - JOUR AB - BACKGROUND: Inattention blindness (IB) can be defined as the failure to perceive an unexpected object when attention is focussed on another object or task. The principal aim of this study was to determine the effect of cognitive load and surgical image guidance on operative IB. METHODS: Using a randomised control study design, participants were allocated to a high or low cognitive load group and subsequently to one of three augmented reality (AR) image guidance groups (no guidance, wireframe overlay and solid overlay). Randomised participants watched a segment of video from a robotic partial nephrectomy. Those in the high cognitive load groups were asked to keep a count of instrument movements, while those in the low cognitive load groups were only asked to watch the video. Two foreign bodies were visible within the operative scene: a swab, within the periphery of vision; and a suture, in the centre of the operative scene. Once the participants had finished watching the video, they were asked to report whether they had observed a swab or suture. RESULTS: The overall level of prompted inattention blindness was 74 and 10 % for the swab and suture, respectively. Significantly higher levels of IB for the swab were seen in the high versus the low cognitive load groups, but not for the suture (8 vs. 47 %, p < 0.001 and 90 vs. 91 %, p = 1.000, for swab and suture, respectively). No significant difference was seen between image guidance groups for attention of the swab or suture (29 vs. 20 %, p = 0.520 and 22 vs. 22 %, p = 1.000, respectively). CONCLUSIONS: The overall effect of IB on operative practice appeared to be significant, within the context of this study. When examining for the effects of AR image guidance and cognitive load on IB, only the latter was found to have significance. AD - Department of Surgery and Cancer, Imperial College London, St Mary's Hospital Campus, London, W2 1NY, UK. a.hughes-hallett@imperial.ac.uk. Department of Surgery and Cancer, Imperial College London, St Mary's Hospital Campus, London, W2 1NY, UK. e.mayer@imperial.ac.uk. Department of Surgery and Cancer, Imperial College London, St Mary's Hospital Campus, London, W2 1NY, UK. Hamlyn Centre, Institute of Global Health Innovation, Imperial College London, London, UK. AN - 25582962 AU - Hughes-Hallett, A. AU - Mayer, E. K. AU - Marcus, H. J. AU - Pratt, P. AU - Mason, S. AU - Darzi, A. W. AU - Vale, J. A. DA - Nov DO - 10.1007/s00464-014-4051-3 DP - NLM ET - 2015/01/15 IS - 11 KW - Adult *Attention Burnout, Professional/*etiology/physiopathology/psychology *Clinical Competence Cognition/*physiology Female Humans Male Pilot Projects Surgeons/*psychology Surgical Procedures, Operative/*standards Video Recording Workload/*psychology Augmented reality Cognitive load Inattention blindness Laparoscopic Safety Surgery LA - eng N1 - 1432-2218 Hughes-Hallett, Archie Mayer, Erik K Marcus, Hani J Pratt, Philip Mason, Sam Darzi, Ara W Vale, Justin A Journal Article Randomized Controlled Trial Germany Surg Endosc. 2015 Nov;29(11):3184-9. doi: 10.1007/s00464-014-4051-3. Epub 2015 Jan 13. PY - 2015 SN - 0930-2794 SP - 3184-9 ST - Inattention blindness in surgery T2 - Surg Endosc TI - Inattention blindness in surgery VL - 29 ID - 157 ER - TY - JOUR AB - The NuvaRing® is a deformable, ring-shaped hormonal contraceptive device which is typically vaginally self-inserted by the patient. While there are several potential side effects of usage, essentially all of them result from hormone delivery. Complications from incorrect placement are rare. We present the case of a 31 year old female who presented to our emergency department after being unable to retrieve a NuvaRing® for its scheduled removal. CT scan showed a hypodense intravesicular NuvaRing® which the patient had inadvertently placed transurethrally 3 weeks prior. Cystoscopy was performed and retrieval using a 3-pronged grasper was eventually successful after several failed attempts with an alligator grasper. Our purpose in presenting this case is to introduce the reader to a rare complication of incorrect NuvaRing® placement, explain how this complication may occur as a result of NuvaRing® construction/functionality, describe how alternative cystoscopic instruments may aid in cystoscopic retrieval, and review the 3 other case reports of intravesicular NuvaRing® placement to discuss the utility of various imaging modalities when clinical suspicion of the complication is high. © 2014, EduRad. All rights reserved. AD - Department of Radiology, Stony Brook University Medical Center, Stony Brook, NY, United States AU - Baker, K. S. AU - Barish, M. DB - Scopus DO - 10.3941/jrcr.v8i12.2304 IS - 12 KW - Contraception radiology Contraceptive ring CT imaging Foreign body Intravesicular foreign body NuvaRing M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2014 SP - 22-28 ST - Inadvertent intravesicular placement of a vaginal contraceptive ring: A case report and review of literature T2 - Journal of Radiology Case Reports TI - Inadvertent intravesicular placement of a vaginal contraceptive ring: A case report and review of literature UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84919675136&doi=10.3941%2fjrcr.v8i12.2304&partnerID=40&md5=a94840060e5c21f20df30eb37192810b VL - 8 ID - 1282 ER - TY - JOUR AD - PERIOPERATIVE NURSING SPECIALIST, AORN NURSING DEPARTMENT AN - 103895026. Language: English. Entry Date: 20140929. Revision Date: 20150818. Publication Type: Journal Article AU - Denholm, Bonnie DB - ccm DP - EBSCOhost IS - 4 KW - Surgical Sponges Surgical Count Procedure Education, Continuing (Credit) Perioperative Nursing Registered Nurses N1 - brief item; questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 0372403. PY - 2014 SN - 0001-2092 SP - 442-443 ST - Inaccurate sponge counts in custom packs T2 - AORN Journal TI - Inaccurate sponge counts in custom packs UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103895026&site=ehost-live&scope=site VL - 100 ID - 809 ER - TY - JOUR AB - Background: Pseudomonas aeruginosa is one of the major pathogens causing morbidity and mortality in hospital acquired infections (HAI).MDRP. aeruginosa are resistant to 3 or more classes of antibiotics. In cUTI cases catheter associated infections are incurable by most of the antibiotics. Compound A a novel Leu-t-RNA synthetase inhibitor showed efficacy in mouse ascending urinary tract infection (AUTI) model against P. aeruginosa biofilms formed on urinary catheters. Methods & Materials: In this study we established a mouse model of foreign body associated AUTI. A spiral polyethylene tube (PT) was placed transurethrally into bladder without surgical manipulation, followed by transurethral inoculation with Pseudomonas aeruginosa 1594965 (MDR) strain. Scanning electron microscopy (SEM) was done after 4h of inoculation of bacteria and bacterial counts were taken in kidneys, bladders and catheter pieces for respective samples. In vivo efficacy of Compound A was tested using this established model against P. aeruginosa 1594965(Compound A MIC: 1μg/ml, meropenem MIC: 32μg/ml). Compound A was tested at 30 and 220mg/kg SC q6h and meropenem was tested at human simulated dose of 60 mg/kg SC q6h. The treatment was initiated 4h post infection and continued daily for 7 days. Bacterial counts of placebo 4h, 7 days and 7 days treated group's samples of kidneys, bladders and catheters were calculated. Data was analysed using bacterial counts of each group and compared with those of 4 h placebo control group. Results: SEM showed good establishment of biofilm in 4 h samples. In foreign body associated mouse infection model. LRS inhibitor Compound A at 30, 220 mg/kg SC q6h showed log10 difference of -2.38, -2.18 log10 CFU/kidney respectively compared to 4h placebo and meropenemat 60 mg/kg SC q6h was inefficacious. In bladders this log difference was -2.30, -1.21, -0.78 respectively. On catheter only Compound A at 220mg/kg SC q6h showed log10 difference of -1.59 log10CFU/ml. No efficacy was observed in remaining groups Conclusion: Efficacy of Compound A in foreign body associated mouse AUTI infection model against MDR Pseudomonas aeruginosa 1594965 proves its efficacy on biofilm. These results warrant its further investigation in HAI associated Pseudomonas aeruginosa infections. AD - K.P. Purnapatre, Daiichi Sankyo India Pharma Private Limited, Gurgaon, India AU - Kumar, M. AU - Rao, M. AU - Barman, T. K. AU - Pandya, M. AU - Dube, S. AU - Purnapatre, K. P. DB - Embase DO - 10.1016/j.ijid.2016.02.320 KW - RNA transfer RNA placebo meropenem antibiotic agent 1 (5 isoquinolinesulfonyl) 2 methylpiperazine synthetase polyethylene urinary tract infection foreign body Pseudomonas aeruginosa model infection mouse bladder biofilm catheter bacterial count human scanning electron microscopy kidney inoculation hospital infection Pseudomonas infection minimum inhibitory concentration catheter infection mortality tube bacterium morbidity mouse model control group urinary catheter pathogenesis LA - English M3 - Conference Abstract N1 - L72245273 2016-04-21 PY - 2016 SN - 1201-9712 SP - 129 ST - In-vivo efficacy of a novel Leu-t-RNA synthatase inhibitor compound a against MDR Pseudomonas aeruginosa 1594965 in a foreign body associated urinary tract infection model T2 - International Journal of Infectious Diseases TI - In-vivo efficacy of a novel Leu-t-RNA synthatase inhibitor compound a against MDR Pseudomonas aeruginosa 1594965 in a foreign body associated urinary tract infection model UR - https://www.embase.com/search/results?subaction=viewrecord&id=L72245273&from=export http://dx.doi.org/10.1016/j.ijid.2016.02.320 VL - 45 ID - 407 ER - TY - JOUR AB - Polymorphonuclear leukocytes, monocytes/macrophages, foreign body giant cells (FBGC), and lymphocytes are central in directing the host foreign body and inflammatory/immune reactions that impact material biostability, biocompatibility, and device efficacy. We employed the functional architecture of fibronectin to probe the mechanisms of protein-cell interaction in modulating leukocyte behavior. We demonstrated previously that the RGD and PHSRN domain of fibronectin and the spatial orientation between the motifs were crucial in regulating macrophage function in vitro. The current study delineates the role of RGD and PHSRN in modulating the host inflammatory response and macrophage behavior in vivo. Oligopeptides containing RGD and/or PHSRN domains were grafted onto a polyethyleneglycol-based substrate and subcutaneously cage implanted into rats. Peptide identity played a minimal role in modulating the host inflammatory response and adherent macrophage density. The RGD motif, either alone or at the terminal position with the PHSRN-containing flanking sequence, elicited a rapid macrophage fusion to form FBGCs at the early stage of implantation. Both the RGD motif and the PHSRN motif were important in mediating FBGC formation at the later implantation time. However, the PHSRN motif, specifically in the configuration of G3RGDG6PHSRNG, evoked a larger extent of FBGC coverage. Our results indicate the importance of RGD and PHSRN in modulating macrophage function in a time and orientation dependent fashion in vivo. © 2001 Elsevier Science Ltd. All rights reserved. AD - Department of Biomedical Engineering, School of Pharmacy, University of Wisconsin-Madison, Madison, WI 53706-1515, United States Department of Biochemistry, University of Wisconsin-Madison, 425 N. Charter Street, Madison, WI 53706-1515, United States AU - Kao, W. J. AU - Lee, D. DB - Scopus DO - 10.1016/S0142-9612(01)00037-0 IS - 21 KW - Extracellular matrix proteins Foreign body giant cells Inflammation Leukocytes Polyethyleneglycols M3 - Article N1 - Cited By :66 Export Date: 10 November 2020 PY - 2001 SP - 2901-2909 ST - In vivo modulation of host response and macrophage behavior by polymer networks grafted with fibronectin-derived biomimetic oligopeptides: The role of RGD and PHSRN domains T2 - Biomaterials TI - In vivo modulation of host response and macrophage behavior by polymer networks grafted with fibronectin-derived biomimetic oligopeptides: The role of RGD and PHSRN domains UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034910711&doi=10.1016%2fS0142-9612%2801%2900037-0&partnerID=40&md5=7a09ac44fd9589f2228085569a66a4dc VL - 22 ID - 1669 ER - TY - JOUR AB - Tissue engineered scaffolds (TES) hold promise for improving the outcome of cell-based therapeutic strategies for a variety of biomedical scenarios, including musculoskeletal injuries, soft tissue repair, and spinal cord injury. Key to TES research and development, and clinical use, is the ability to longitudinally monitor TES location, orientation, integrity, and microstructure following implantation. Here, we describe a strategy for using microcomputed tomography (microCT) to visualize TES following implantation into mice. TES were doped with highly radiopaque gadolinium oxide nanocrystals and were implanted into the hind limbs of mice. Mice underwent serial microCT over 23 weeks. TES were clearly visible over the entire time course. Alginate scaffolds underwent a 20% volume reduction over the first 6 weeks, stabilizing over the next 17 weeks. Agarose scaffold volumes were unchanged. TES attenuation was also unchanged over the entire time course, indicating a lack of nanocrystal dissolution or leakage. Histology at the implant site showed the presence of very mild inflammation, typical for a mild foreign body reaction. Blood work indicated marked elevation in liver enzymes, and hematology measured significant reduction in white blood cell counts. While extrapolation of the X-ray induced effects on hematopoiesis in these mice to humans is not straightforward, clearly this is an area for careful monitoring. Taken together, these data lend strong support that doping TES with radiopaque nanocrystals and performing microCT imaging, represents a possible strategy for enabling serial in vivo monitoring of TES. AD - Department of Radiology, Michigan State University, 846 Service Road, East Lansing, Michigan 48824, United States. Department of Small Animal Clinical Sciences, Michigan State University, 736 Wilson Road, East Lansing, Michigan 48824, United States. Department of Pathobiology and Diagnostic Investigation, Michigan State University, 736 Wilson Road, East Lansing, Michigan 48824, United States. Department of Mechanical Engineering, University of Michigan, 2350 Hayward Avenue, Ann Arbor, Michigan 48109, United States. AN - 30035211 AU - Forton, S. M. AU - Latourette, M. T. AU - Parys, M. AU - Kiupel, M. AU - Shahriari, D. AU - Sakamoto, J. S. AU - Shapiro, E. M. C2 - PMC6054471 C6 - NIHMS944458 DA - Apr 11 DO - 10.1021/acsbiomaterials.5b00476 DP - NLM ET - 2016/04/11 IS - 4 KW - Hounsfield units X-ray agarose alginate biomedical imaging bismuth gadolinium oxide microCT tissue engineered scaffold LA - eng N1 - 2373-9878 Forton, Stacey M Latourette, Matthew T Parys, Maciej Kiupel, Matti Shahriari, Dena Sakamoto, Jeff S Shapiro, Erik M R21 EB017881/EB/NIBIB NIH HHS/United States Journal Article ACS Biomater Sci Eng. 2016 Apr 11;2(4):508-516. doi: 10.1021/acsbiomaterials.5b00476. Epub 2016 Feb 29. PY - 2016 SN - 2373-9878 (Print) 2373-9878 SP - 508-516 ST - In Vivo Microcomputed Tomography of Nanocrystal-Doped Tissue Engineered Scaffolds T2 - ACS Biomater Sci Eng TI - In Vivo Microcomputed Tomography of Nanocrystal-Doped Tissue Engineered Scaffolds VL - 2 ID - 174 ER - TY - JOUR AB - The peritoneal cavity of the rat was used as an implantation site in order to study the quantitative, cellular response and the qualitative, histopathological response to three metals (Ag, Sn, Cu). The effects of the metals on the cells were correlated with the cellular concentrations of the metal as determined by chemical analysis. Small variations in the cell population and a minimal foreign body reaction was observed with an implanted control material (silicone polymer). Large increases in the number of cells and an intense foreign body reaction was observed with Cu implants. Decreases in the number of cells were seen with Sn and Ag implants, but only Sn elicited a foreign body reaction. Implantation of Ag failed to elicit a foreign body reaction. Significant concentrations of all three metals were detected in the retrieved cells. Copyright © 1984 John Wiley & Sons, Inc. AD - Department of Biological Materials, Northwestern University, Chicago, Illinois, 60611, United States Department of Pathology, Northwestern University, Chicago, Illinois, 60611, United States AU - Keller, J. C. AU - Marshall, G. W. AU - Kaminski, E. J. DB - Scopus DO - 10.1002/jbm.820180713 IS - 7 M3 - Article N1 - Cited By :14 Export Date: 10 November 2020 PY - 1984 SP - 829-844 ST - An in vivo method for the biological evaluation of metal implants T2 - Journal of Biomedical Materials Research TI - An in vivo method for the biological evaluation of metal implants UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021491348&doi=10.1002%2fjbm.820180713&partnerID=40&md5=89cb4c5dd132ed5742a160948e19a21b VL - 18 ID - 1753 ER - TY - JOUR AB - The early biological response at titanium (Ti), copper (Cu)-coated Ti and sham sites was evaluated in an in vivo rat model. Material surface chemical and topographical properties were characterized using Auger electron spectroscopy, energy dispersive X-ray spectroscopy and interferometry, respectively. The number of leukocytes, cell types and cell viability (release of lactate dehydrogenase) were determined in the implant-interface exudate. The contents of activated nuclear transcription factor NF-κB, interleukin-6 (IL-6) and interleukin-10 (IL-10) were determined by enzyme linked immunosorbent assay. An increase in the number of leukocytes, in particular, polymorphonuclear leukocytes, was observed between 12 and 48h around Cu. A marked decrease of exudate cell viability was found around Cu after 48h. The total amounts of activated NF-κB after 12h was highest in Ti exudates whereas after 48h the highest amount of NF-κB was detected around Cu. The levels of cytokine IL-6 were consistently high around Cu at both time periods. No differences in IL-10 contents were detected, irrespective of material/sham and time. The results show that materials with different toxicity grades (titanium with low and copper with high toxicity) exhibit early differences in the activation of NF-κB, extracellular expression and secretion of mediators, causing major differences in inflammatory cell accumulation and death in vivo. © 2004 Elsevier Ltd. All rights reserved. AD - Department of Biomaterials, Institute of Surgical Sciences, Sahlgrenska Acad. Goteborg Univ., M., Göteborg, Sweden Laboratory of Applied Physics, Linköping University, SE-581 83, Linköping, Sweden AU - Suska, F. AU - Gretzer, C. AU - Esposito, M. AU - Emanuelsson, L. AU - Wennerberg, A. AU - Tengvall, P. AU - Thomsen, P. DB - Scopus DO - 10.1016/j.biomaterials.2004.02.066 IS - 5 KW - Copper Cytokine Inflammation Titanium M3 - Article N1 - Cited By :46 Export Date: 10 November 2020 PY - 2005 SP - 519-527 ST - In vivo cytokine secretion and NF-κB activation around titanium and copper implants T2 - Biomaterials TI - In vivo cytokine secretion and NF-κB activation around titanium and copper implants UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-3242792640&doi=10.1016%2fj.biomaterials.2004.02.066&partnerID=40&md5=08514e55141f5bf3a7ab4e657ae1dd96 VL - 26 ID - 1614 ER - TY - JOUR AB - PURPOSE: To examine and compare the density and distribution of Langerhans cells (LCs) in the corneal epithelium of healthy volunteers and contact lens wearers. METHODS: A total of 225 eyes of 130 healthy volunteers (age, 17-81 years) without history of ocular inflammation, trauma, or surgery and 98 eyes of 55 contact lens wearers (age, 13-76 years) were examined in vivo with the combination of the Heidelberg Retina Tomograph II and in-house-invented Rostock Cornea Module. RESULTS: In healthy volunteers, in vivo confocal microscopy revealed LCs in 31% of all volunteers, with 37 of these 43 volunteers presenting LCs both in the center and the periphery of the cornea with densities of 34 ± 3 and 98 ± 8 cells/mm, respectively. In the group of contact lens wearers, 55% of all corneas presented with LCs, and 11 of these 33 corneas revealed LCs at central and peripheral locations. Although LC densities were markedly higher in both the central (78 ± 25 cells/mm) and the peripheral cornea (210 ± 24 cells/mm) of contact lens wearers, the gradient of LC density from peripheral to central cornea was found almost identical in both groups. In the central cornea, LC density decreased with duration of contact lens wear. LCs were located at the depth of 35 to 60 μm (ie, the level of lower intermediate cells, basal cells, and subepithelial nervous plexus). LCs presented as either large cells bearing long processes or smaller cells lacking cell dendrites, most supposedly indicating mature and immature phenotype, respectively. CONCLUSIONS: In vivo confocal microscopy enables evaluation of LC density and distribution in corneal epithelium. LCs were found present both in the center and the periphery of the cornea without difference in distribution between healthy volunteers and contact lens wearers. However, contact lens wearers revealed almost twofold higher LC densities in both locations, implying chronic mechanical irritation of the cornea in response to the contact lens as foreign body. Taken together, analysis of LC using in vivo confocal microscopy provides helpful information for a better understanding of contact lens-disturbed ocular homeostasis. © 2007 Lippincott Williams & Wilkins, Inc. AD - Department of Ophthalmology, University of Rostock, Rostock, Germany Department of Experimental Surgery, University of Rostock, Rostock, Germany Department of Experimental Surgery, University of Rostock, Schillingallee 70, 18055 Rostock, Germany AU - Zhivov, A. AU - Stave, J. AU - Vollmar, B. AU - Guthoff, R. DB - Scopus DO - 10.1097/ICO.0b013e31802e3b55 IS - 1 KW - Contact lens Cornea Epithelium In vivo confocal microscopy Langerhans cells M3 - Article N1 - Cited By :109 Export Date: 10 November 2020 PY - 2007 SP - 47-54 ST - In vivo confocal microscopic evaluation of langerhans cell density and distribution in the corneal epithelium of healthy volunteers and contact lens wearers T2 - Cornea TI - In vivo confocal microscopic evaluation of langerhans cell density and distribution in the corneal epithelium of healthy volunteers and contact lens wearers UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33845990569&doi=10.1097%2fICO.0b013e31802e3b55&partnerID=40&md5=2fde0669bed422d521444ee7ee938330 VL - 26 ID - 1574 ER - TY - JOUR AB - Study Objective: MONOFIX, a new absorbable barbed suture device, has a triangular stopper at the end to hold the suture to the tissue without hooking the looped end or knotting. The aim of this study was to compare the biomechanical strength and histologic features of MONOFIX with other barbed suture devices using a porcine model. Design: Well-designed, controlled trial without randomization. Setting: Animal laboratory in university hospital. Subjects: Sixteen, 60-kg, mature female domestic pigs (skin closure group) and 5, 60-kg, mature female domestic pigs (fascial closure group). Interventions: In the skin closure group, 3-0 MONOFIX versus 2 widely used 3-0 absorbable barbed sutures (3-0 V-Loc 180 or Stratafix). In the fascial closure group, 2-0 MONOFIX versus 1 widely used 2-0 absorbable barbed sutures (2-0 Stratafix). Measurements and Main Results: In the skin closure group, the biomechanical wound strength of skin sutured with size 3-0 MONOFIX, V-Loc 180, or Stratafix was evaluated by postoperative day assessment (days 0, 3, 7, 14, and 28). In the fascial closure group, pigs underwent 2 paramedian incisions and were sutured with 2-0 MONOFIX or with 2-0 Stratafix to evaluate histologic reaction. At 6 weeks the tissues around the suture line were excised and microscopically evaluated. The biomechanical strength of the MONOFIX had similar tissue tensile strength compared with the control, regardless of postoperative day. In the fascial closure model, there was no significant difference in the average tissue reaction score between MONOFIX and Stratafix (1.2 ±.3 vs 1.3 ±.3, p = .478). Conclusion: This study demonstrated that MONOFIX has equivalent tensile strength and histologic reaction when compared with commonly used barbed suture devices. Accordingly, this preclinical study suggests that the use of MONOFIX is a safe alternative to other barbed suture devices. © 2019 AD - Departments of Obstetrics and Gynecology Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea Medical Device Program Biology & Clinical Department Samyang Biopharmaceuticals Corporation, Sungnam-si, Korea, and Medical Device Plant, Samyang Biopharmaceuticals, Daejeon, South Korea AU - Kim, J. AU - Eom, H. J. AU - Shin, H. AU - Jeong, S. Y. AU - Kim, M. S. AU - Yoon, H. S. AU - In, C. H. AU - Kim, B. G. AU - Bae, D. S. AU - Lee, J. W. DB - Scopus DO - 10.1016/j.jmig.2019.04.005 IS - 2 KW - Barbed suture Biomechanics Histology In vivo Laparoscopic surgery M3 - Article N1 - Export Date: 10 November 2020 PY - 2020 SP - 473-481 ST - In Vivo Comparison of MONOFIX, A Novel Barbed Suture with a Triangular Stopper, with Pre-existing Products in a Porcine Model T2 - Journal of Minimally Invasive Gynecology TI - In Vivo Comparison of MONOFIX, A Novel Barbed Suture with a Triangular Stopper, with Pre-existing Products in a Porcine Model UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065064715&doi=10.1016%2fj.jmig.2019.04.005&partnerID=40&md5=4eb79391dd9cb947f25607a2982292fe VL - 27 ID - 976 ER - TY - JOUR AB - The present study was undertaken to evaluate a new prototype mesh that consists of a knitted polyester structure treated with a fluoropolymer and impregnated with gelatin. The Fluoropassiv® mesh, as well as two controls, the Surgipro(TM) polypropylene mesh and the Gore-Tex® expanded polytetrafluoroethylene patch, were used for the repair of experimentally induced abdominal hernias in piglets and followed for scheduled implantation periods of 4, 15, and 60 days. At the sacrifice the mesh and surrounding tissue were excised for histological assessment of the healing sequence, for the identification of changes in hematologic and immunological characteristics, and for the measurement of the mechanical properties. After cleaning to remove the encroaching tissue, the explanted devices were monitored for biostability by infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC). The present study has demonstrated that the Fluoropassiv® mesh provides adequate mechanical strength and compares favorably with the two controls. No exacerbated systemic or in situ hematologic or immunological reactions were observed with either the meshes or the patch material. Histological studies revealed that thick collagenous and vascularized tissue were well anchored to the three biomaterials as early as 15 days after implantation. The degree of tissue penetration differed depending on the device. Chemically, they proved stable over time. The present study was undertaken to evaluate a new prototype mesh that consists of a knitted polyester structure treated with a fluoropolymer and impregnated with gelatin. The Fluoropassiv mesh, as well as two controls, the Surgipro polypropylene mesh and the Gore-Tex expanded polytetrafluoroethylene patch, were used for the repair of experimentally induced abdominal hernias in piglets and followed for scheduled implantation periods of 4, 15, and 60 days. At the sacrifice the mesh and surrounding tissue were excised for histological assessment of the healing sequence, for the identification of changes in hematologic and immunological characteristics, and for the measurement of the mechanical properties. After cleaning to remove the encroaching tissue, the explanted devices were monitored for biostability by infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC). The present study has demonstrated that the Fluoropassiv mesh provides adequate mechanical strength and compares favorably with the two controls. No exacerbated systemic or in situ hematologic or immunological reactions were observed with either the meshes or the patch material. Histological studies revealed that thick collagenous and vascularized tissue were well anchored to the three biomaterials as early as 15 days after implantation. The degree of tissue penetration differed depending on the device. Chemically, they proved stable over time. AD - Department of Surgery, Laval University, St-François d'Assise Hospital, Quebec City, Que. G1L 3L5, Canada Laboratory of Experimental Surgery, Pavillon des Services, Université Laval, Quebec City, Que. G1K 7P4, Canada AU - Soares, B. M. AU - Guidoin, R. G. AU - Marois, Y. AU - Martin, L. AU - King, M. W. AU - Laroche, G. AU - Zhang, Z. AU - Charara, J. AU - Girard, J. F. DB - Scopus DO - 10.1002/(SICI)1097-4636(199611)32:3<293::AID-JBM2>3.0.CO;2-N IS - 3 M3 - Article N1 - Cited By :23 Export Date: 10 November 2020 PY - 1996 SP - 293-305 ST - In vivo characterization of a fluoropassivated gelatin-impregnated polyester mesh for hernia repair T2 - Journal of Biomedical Materials Research TI - In vivo characterization of a fluoropassivated gelatin-impregnated polyester mesh for hernia repair UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030297766&doi=10.1002%2f%28SICI%291097-4636%28199611%2932%3a3%3c293%3a%3aAID-JBM2%3e3.0.CO%3b2-N&partnerID=40&md5=b4a2eda3bb29541bdbc0ebbaaf39cfc6 VL - 32 ID - 1714 ER - TY - JOUR AB - Films of three ABA-block copolymers composed of lacticco-glycolic acid A blocks and poly(oxyethylene) (PEO) B blocks and one random lactic-co-glycolic acid copolymer (PLG) were studied to investigate the influence of different polymer compositions and molecular weights on the tissue reaction, appearance of toxic degradation products, and swelling behavior in the cage implant system in rats. The inflammatory tissue reaction was followed over a 21-day implantation period by monitoring the leukocyte concentration, the extracellular acid, and alkaline phosphatase activities in a quantitative manner. Size and density of adherent macrophages and foreign body giant cells on the film surfaces were determined. The ABA and PLG implants caused only a minimal inflammatory reaction, as characterized by a low concentration of leukocytes during the implantation period when compared to empty cage controls. The content of PEO had an influence on the density of the adherent cells on the surface of the polymer film. An increase in PEO content and molecular weight decreased the cellular density during the implantation period. As demonstrated by scanning electron microscopy, no degradation was observed for all polymers during the implantation period. Our results demonstrate that the ABA block copolymers and PLG copolymer are equally well tolerated in the cage implant test system. ©1996 John Wiley & Sons, Inc. AD - Department of Pharmaceutics, Philipps University, Ketzerbach 63, D-35032, Marburg, Germany Department of Macromolecular Science, Case Western Reserve University, Cleveland, OH 44106-2622, United States Institute of Pathology, Case Western Reserve University, Cleveland, OH 44106-2622, United States AU - Ronneberger, B. AU - Kao, W. J. AU - Andersen, J. M. AU - Kissel, T. DB - Scopus DO - 10.1002/(sici)1097-4636(199601)30:1<31::aid-jbm5>3.0.co;2-s IS - 1 M3 - Article N1 - Cited By :99 Export Date: 10 November 2020 PY - 1996 SP - 31-40 ST - In vivo biocompatibility study of ABA triblock copolymers consisting of poly(L-lactic-eo-glycolic acid) A blocks attached to central poly(oxyethylene) B blocks T2 - Journal of Biomedical Materials Research TI - In vivo biocompatibility study of ABA triblock copolymers consisting of poly(L-lactic-eo-glycolic acid) A blocks attached to central poly(oxyethylene) B blocks UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030064723&doi=10.1002%2f%28sici%291097-4636%28199601%2930%3a1%3c31%3a%3aaid-jbm5%3e3.0.co%3b2-s&partnerID=40&md5=d75e998c61776d5363e60df16fec2ee0 VL - 30 ID - 1720 ER - TY - JOUR AB - A cage implant system was utilized to quantitatively and qualitatively characterize in vivo leukocyte interactions with cast Biomer. Scanning electron microscopy (SEM) in conjunction with cytochemical staining procedures were used to investigate the cellular events at the leukocyte/Biomer interface as well as in the inflammatory exudate over a 21‐day implantation period. SEM was used to characterize leukocyte morphology on the Biomer surface and the cytochemical stains were used to differentially count leukocytes and to demonstrate intracellular alkaline and acid phosphatase activity. The results showed that the population density of leukocytes on the Biomer surface diminished with implantation time. The population density of multinucleated foreign body giant cells remained constant with time, while the numbers of nuclei per giant cell increased. The differential analysis revealed that macrophages preferentially adhered to the Biomer surface compared to other leukocytes in the exudate. The phagocytic capability of all adherent leukocytes, including giant cells, decreased with time and this corresponded to changes in leukocyte morphology observed with SEM. Copyright © 1984 John Wiley & Sons, Inc. AD - Departments of Macromolecular Science and Pathology, Case Western Reserve University, Cleveland, Ohio, 44106, United States AU - Marchant, R. E. AU - Miller, K. M. AU - Anderson, J. M. DB - Scopus DO - 10.1002/jbm.820180917 IS - 9 M3 - Article N1 - Cited By :108 Export Date: 10 November 2020 PY - 1984 SP - 1169-1190 ST - In vivo biocompatibility studies. V. In vivo leukocyte interactions with biomer T2 - Journal of Biomedical Materials Research TI - In vivo biocompatibility studies. V. In vivo leukocyte interactions with biomer UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021682433&doi=10.1002%2fjbm.820180917&partnerID=40&md5=ce7ba37440df7ab7e4a09ecf68d26d1a VL - 18 ID - 1754 ER - TY - JOUR AB - The in vivo erosion behavior of crosslinked (co)polymers based on trimethylene carbonate (TMC) and ε-caprolactone (CL) was investigated. High molecular weight poly(trimethylene carbonate) (PTMC) homopolymer-and copolymer films were crosslinked by gamma irradiation. To adjust the in vivo erosion rate of the (co)polymer films, both the irradiation dose (25, 50, or 100 kGy) for PTMC and composition (100-70 mol % TMC) at a constant irradiation dose of 25 kGy were varied. After subcutaneous implantation of irradiated films in rats, their in vivo behavior was evaluated qualitatively and quantitatively. When the irradiation dose for PTMC was increased from 25 to 100 kGy, the erosion rate of nonextracted PTMC films (determined at day 5) decreased from 39.7 ± 16.0 μm day-1 to 15.1 ± 2.5 μm day-1, and the number of lymphocytes in the tissue surrounding the films decreased from 235 ± 114 cells mm-2 to 64 ± 33 cells mm-2. The number of macrophages and giant cells at the tissue-polymer interface also decreased with increasing irradiation dose. All (co)polymer films eroded completely within 28 days of implantation. Variation of the TMC content of gamma irradiated (co)polymer films did not affect the tissue response to the gamma irradiated (co)polymer films and their in vivo erosion behavior much. © 2010 Wiley Periodicals, Inc. AD - Department of Polymer Chemistry and Biomaterials, MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, P.O. Box 217, 7500 AE Enschede, Netherlands Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, Netherlands Department of Biomedical Engineering, University Medical Center Groningen, University of Groningen, A. Deusinglaan 1, 9713 AV Groningen, Netherlands AU - Bat, E. AU - Plantinga, J. A. AU - Harmsen, M. C. AU - Van Luyn, M. J. A. AU - Feijen, J. AU - Grijpma, D. W. DB - Scopus DO - 10.1002/jbm.a.32921 IS - 3 A KW - Crosslinking by gamma irradiation In vivo erosion Poly(trimethylene carbonate) Tissue response Trimethylene carbonate and ε-caprolactone copolymers M3 - Article N1 - Cited By :34 Export Date: 10 November 2020 PY - 2010 SP - 940-949 ST - In vivo behavior of trimethylene carbonate and ε-caprolactone-based (co)polymer networks: Degradation and tissue response T2 - Journal of Biomedical Materials Research - Part A TI - In vivo behavior of trimethylene carbonate and ε-caprolactone-based (co)polymer networks: Degradation and tissue response UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-78249261490&doi=10.1002%2fjbm.a.32921&partnerID=40&md5=d1f29c8d71b3b0f7ba84fcb8a8d90533 VL - 95 ID - 1444 ER - TY - JOUR AB - Calcification limits the long-term durability of xenograft glutaraldehyde-crosslinked heart valves. In this study, epoxy-crosslinked porcine aortic valve tissue was evaluated after subcutaneous implantation in weanling rats. Non-crosslinked valves and valves crosslinked with glutaraldehyde or carbodiimide functioned as control. Epoxy-crosslinked valves had somewhat lower shrinkage temperatures than the crosslinked controls, and within the series also some macroscopic and microscopic differences were obvious. After 8 weeks implantation, cusps from non- crosslinked valves were not retrieved. The matching walls were more degraded than the epoxy- and control-crosslinked walls. This was observed from the higher cellular ingrowth with fibroblasts, macrophages, and giant cells. Furthermore, non-crosslinked walls showed highest numbers of lymphocytes, which were most obvious in the capsules. Epoxy- and control-crosslinked cusps and walls induced lower reactions. Calcification, measured by von Kossa- staining and by Ca-analysis, was always observed. Crosslinked cusps calcified more than walls. Of all wall samples, the non-crosslinked walls showed the highest calcification. It is concluded that epoxy-crosslinked valve tissue induced a foreign body and calcification reaction similar to the two crosslinked controls. Therefore, epoxy-crosslinking does not represent a solution for the calcification problem of heart valve bioprostheses. Calcification limits the long-term durability of xenograft glutaraldehyde-crosslinked heart valves. In this study, epoxy-crosslinked porcine aortic valve tissue was evaluated after subcutaneous implantation in weanling rats. Non-crosslinked valves and valves crosslinked with glutaraldehyde or carbodiimide functioned as control. Epoxy-crosslinked valves had somewhat lower shrinkage temperatures than the crosslinked controls, and within the series also some macroscopic and microscopic differences were obvious. After 8 weeks implantation, cusps from non-crosslinked valves were not retrieved. The matching walls were more degraded than the epoxy- and control-crosslinked walls. This was observed from the higher cellular ingrowth with fibroblasts, macrophages, and giant cells. Furthermore, non-crosslinked walls showed highest numbers of lymphocytes, which were most obvious in the capsules. Epoxy- and control-crosslinked cusps and walls induced lower reactions. Calcification, measured by von Kossa-staining and by Ca-analysis, was always observed. Crosslinked cusps calcified more than walls. Of all wall samples, the non-crosslinked walls showed the highest calcification. It is concluded that epoxy-crosslinked valve tissue induced a foreign body and calcification reaction similar to the two crosslinked controls. Therefore, epoxy-crosslinking does not represent a solution for the calcification problem of heart valve bioprostheses. AD - University of Groningen, Fac. for Med. Sci., Medical Biology, Cell Biology and Biomaterials, Bloemsingel 10-B2, 9712 KZ Groningen, Netherlands University of Twente, Department of Chemical Technology, Institute of Biomedical Technology, P. O. Box 217, 7500 AE Enschede, Netherlands Medtronic Bakken Res. Center B.V., P. O. Box 1220, 6201 MP Maastricht, Netherlands AU - Van Wachem, P. B. AU - Brouwer, L. A. AU - Zeeman, R. AU - Dijkstra, P. J. AU - Feijen, J. AU - Hendriks, M. AU - Cahalan, P. T. AU - Van Luyn, M. J. A. DB - Scopus DO - 10.1002/(SICI)1097-4636(2000)53:1<18::AID-JBM3>3.0.CO;2-J IS - 1 KW - Calcification Crosslinking Epoxy Heart valve Prosthesis M3 - Article N1 - Cited By :24 Export Date: 10 November 2020 PY - 2000 SP - 18-27 ST - In vivo behavior of epoxy-crosslinked porcine heart valve cusps and walls T2 - Journal of Biomedical Materials Research TI - In vivo behavior of epoxy-crosslinked porcine heart valve cusps and walls UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033972637&doi=10.1002%2f%28SICI%291097-4636%282000%2953%3a1%3c18%3a%3aAID-JBM3%3e3.0.CO%3b2-J&partnerID=40&md5=15bfdb7facf9353c76f9b28007969409 VL - 53 ID - 1679 ER - TY - JOUR AB - Introduction & Objectives: Alloplastic materials are widely applied in the surgical therapies for hernia, incontinence and prolapse situations. The American Food and Drug Administration (FDA) issued a warning concerning the application of alloplastic materials for the surgical treatment of female incontinence and prolapse reporting more than 1000 severe adverse events associated with the used materials. Special surgical training together with the management of risk and AE's are recommended (www.fda.gov/cdrh/safety/102008-surgicalmesh.html). The improvement of the biocompatibility coating foreign materials with e.g. autologous substances seems to be mandatory. Material & Methods: In order to investigate if coating of alloplastic materials with autologous material can lead to improved biocompatibility and if alloplastic materials are integrated into the structure of the pelvic floor, the following study approach was established:12 patients were included. Myoblasts, endothelial cells and fibroblasts of each patient were cultivated separately. Cell count and growth are comparable in all approaches within a test duration of 6 weeks. Immunohistochemical and microscopic evaluation of cell count and adherence is performed considering the chosen coating for the alloplastic material. Additionally we performed immunocytochemistry in order to verify the presence of these cells proving the expression of specific cell markers. The detection of myoblasts was realised by α-sarcomeric actin and desmin as markers of myogene differentiation. Fibroblasts were demonstrated by the use of antibodies targeting vimentin whereas antibodies against CD34 were utilised for the detection of endothelial cells. Adherence and cell count are assessed microscopically and by immunohistochemistry after co-incubation of the cells with different types of alloplastic meshs. Results: 14 different, commonly used alloplastic materials were investigated. Cell count and growth were comparable in all approaches within a test duration of 6 weeks. Only on TFT Motifmesh cells are showing adherence and growth. On all other meshs there is no evidence of cell adherence to the respective alloplastic materials. The in vitro analyses were independent from gender and individual patient features. Regarding tissue specify different cell growth can de defined in favour of fibroblasts: fibroblasts > myoblasts > endothelial cells. Improved cell adhesion was found on alloplastic meshs covered with autologous plasma compared to non-covered meshs. This finding includes all types of cells being tested. A covering of meshs with serum or collagen seems to be of disadvantage. Looking at the intensity of cell adhesion on the different meshs the following ranking can be disposed:! TFT Motifmesh®, ProxyBiomedical 2. Dynamesh®, FEG Textiltechnik 3. Surgimesh®, Aspide Medical, Resorba 4. PDS Plate®, Johnson & Johnson 5. Mersliene Band, Johnson & Johnson 6. Vitamesh®, ProxyBiomedical 7. Vicryl Band, Johnson & Johnson 8. TiLoop®, PFMCell adhesion on the following alloplastic materials is not seen neither in the uncovered nor in the covered approach: Ethisorb Patch®, EthiconProceed surgical mesh®, EthiconCollagenmeshResodont mesh®, ResorbaParasorb mesh®, ResorbaDualmesh®, Fa.GoreMycromesh®, Fa.GorePCL scaffoldAdVance male sling®, AMSSeratim®, Serag-Wiessner Conclusions: TFT Motifmesh represents the only alloplastic material that shows in vitro biocompatibility for the cell types characterising the pelvic floor and abdominal wall. Cell adhesion to the tested alloplastic materials regarding cells of the pelvic floor is insufficient. This observation may explain the occurrence of foreign-body reaction and missing integration of alloplastic materials into the pelvic floor. Coating of meshs with autologous plasma results in an improvement of the biocompatibility of alloplastic materials. AD - C. Eimer, Lukas Hospital, Dept. of Urology, Neuss, Germany AU - Eimer, C. AU - Gerullis, H. AU - Bagner, J. AU - Lammers, B. J. AU - Theuerkauf, I. AU - Ramon, A. AU - Otto, T. DB - Embase DO - 10.1016/S1569-9056(10)60256-4 IS - 2 KW - antibody actin desmin marker vimentin collagen polyglactin cell marker biocompatibility in vitro study urology fibroblast cell adhesion cell count pelvis floor patient myoblast endothelium cell surgery blood autotransfusion tissue injury incontinence immunohistochemistry gender tissues cell growth abdominal wall adhesion surgical equipment male cells by body anatomy foreign body reaction hernia Food and Drug Administration female surgical training risk foreign body immunocytochemistry serum LA - English M3 - Conference Abstract N1 - L70146464 2010-05-25 PY - 2010 SN - 1569-9056 SP - 109 ST - In vitro test system for the evaluation of the biocompatibility of alloplastic materials T2 - European Urology, Supplements TI - In vitro test system for the evaluation of the biocompatibility of alloplastic materials UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70146464&from=export http://dx.doi.org/10.1016/S1569-9056(10)60256-4 VL - 9 ID - 570 ER - TY - JOUR AB - Introduction and Objective: Alloplastic materials are widely applied in the surgical therapies for hernia, incontinence and prolapse situations. The FDA issued a warning concerning the application of alloplastic materials for the surgical treatment of female incontinence and prolapse. The improvement of the biocom-patibility of foreign materials seems to be mandatory. Materials and Methods: In order to investigate if coating of alloplastic materials with autologous material can lead to improved biocompatibility the following study approach was established: 12 patients were included. Blood, plasma and serum of each patient were preserved. Myoblasts, endothelial cells and fibroblasts of each patient were cultivated separately with the alloplastic materials. Cell count and growth are comparable in all approaches within a test duration of 6 weeks. Immunohistochemical and microscopic evaluation of cell count and adherence is performed considering the chosen coating for the alloplastic material. Adherence, cell count and typing are assessed microscopically and by immunohisto-chemistry after co-incubation of the cells with different types of alloplastic meshes with and without coatings. Results: Regarding tissue specify different cell growth can de defined in favor of fibroblasts: fibroblasts > myoblasts > endothelial cells. Improved cell adhesion is found on alloplastic meshes covered with autologous plasma compared to noncovered meshes. This finding includes all types of cells being tested. Eighteen different, commonly used alloplastic materials were investigated. Cell count and growth were comparable in all approaches within a test duration of 6 weeks. Only on cPTFE are cells showing adherence and growth. On all other uncovered meshes there is no evidence of cell adherence to the respective alloplastic materials. Looking at the intensity of cell adhesion through plasma-coating on the different meshes a ranking can be compiled. Conclusions: Cell adhesion to the tested alloplastic materials regarding cells of the pelvic floor is insufficient. This observation may explain the occurrence of foreign-body reaction and missing integration of alloplastic materials into the pelvic floor. Coating of meshes with autologous plasma results in an improvement of the biocompatibility. AD - J. Bagner, Dept. of Urology, Staedt Kliniken, Neuss, Germany AU - Bagner, J. AU - Gerullis, H. AU - Karig, R. AU - Ramon, A. AU - Otto, T. DB - Embase DO - 10.1016/j.urology.2010.07.376 IS - 3 KW - in vitro study lower urinary tract symptom cell adhesion cell count fibroblast patient tissue injury myoblast plasma biocompatibility endothelium cell blood autotransfusion pelvis floor incontinence surgery female hernia serum tissues foreign body cell growth foreign body reaction Food and Drug Administration LA - English M3 - Conference Abstract N1 - L70276020 2010-10-14 PY - 2010 SN - 0090-4295 SP - S21-S22 ST - In vitro test system for the evaluation of the biocompability of alloplastic materials and its improvement by autologous coating T2 - Urology TI - In vitro test system for the evaluation of the biocompability of alloplastic materials and its improvement by autologous coating UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70276020&from=export http://dx.doi.org/10.1016/j.urology.2010.07.376 VL - 76 ID - 559 ER - TY - JOUR AB - Introduction and Objective: Alloplastic materials are increasingly applied in continence surgery. GMP conformable trials do not exist. Many of the materials have a strong tissue adherence thus resulting in a foreign material reaction. The purpose of the study was to evaluate the biocompability of different alloplastic materials. Materials and Methods: An in vitro pattern using myoblasts has been established in order to investigate the ability of alloplastic materials to integrate into the pelvic floor muscle or act as foreign material. The expression of the following specific markers of myogenic differentiation was measured (α-SM-actin, SM-actin, Desmin, MyoD1). Each measurement was performed double blinded under identical circumstances regarding cell culture and myoblasts count. The allogenic materials were investigated for six weeks in myoblastic culture. Myoblast count and adherence were evaluated using light optical microscope. Results: The following alloplastic materials have been investigated: Vitamesh, TFT Motifmesh, Ethisorb Patch, Vicrylsling, PDS Plate, Proceed surgical mesh, Mersilan sling, Surgimesh, Collagenmesh, Resodont mesh, Parasorb mesh, PCL scaffold. Cell count and cell growth were compared over 6 weeks. Myoblasts were merely adherent and growing in culture with TFT Motifmesh (Tetrafluoroethylen). We fixed TFT Motifmesh in the tissue with bio adhesive. Myoblast compability was measured using the bio adhesive, resulting in equal myoblast growth and tissue adherence. All other materials investigated in this study did not show myoblast adherence and therefore no myoblast growth on the material. Conclusions: In our study TFT Motifmesh has been the only material showing in vitro biocompability for myoblasts. AD - H. Gerullis, Department of Urology, Lukas Hospital, Neuss, Germany AU - Gerullis, H. AU - Eimer, C. AU - Bagner, J. AU - Otto, T. DB - Embase DO - 10.1016/j.urology.2009.07.642 IS - 4 KW - adhesive agent actin guanosine phosphate marker desmin in vitro study urine incontinence myoblast tissues foreign body surgical equipment cell count surgery cell growth continence pelvis floor cell culture microscope optics LA - English M3 - Conference Abstract N1 - L70085279 2010-03-30 PY - 2009 SN - 0090-4295 SP - S232 ST - In vitro test pattern for determination of biocompability of alloplastic materials used for treatment of urinary incontinence T2 - Urology TI - In vitro test pattern for determination of biocompability of alloplastic materials used for treatment of urinary incontinence UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70085279&from=export http://dx.doi.org/10.1016/j.urology.2009.07.642 VL - 74 ID - 577 ER - TY - JOUR AB - Bridging nerve gaps by means of autologous nerve grafts involves donor nerve graft harvesting. Recent studies have focused on the use of alternative methods, and one of these is the use of biodegradable nerve guides. After serving their function, nerve guides should degrade to avoid a chronic foreign body reaction. The in vitro degradation, in vitro cytotoxicity, hemocompatibility, and short-term in vivo foreign body reaction of poly(65/35(85/15 L/D) lactide-ε-caprolactone) nerve guides was studied. The in vitro degradation characteristics of poly(DLLA-ε-CL) nerve guides were monitored at 2-week time intervals during a period of 22 weeks. Weight loss, degree of swelling of the tube wall, mechanical strength, thermal properties, and the intrinsic viscosity of the nerve guides were determined. Cytotoxicity was studied by measuring the cell proliferation inhibition index (CPII) on mouse fibroblasts in vitro. Cell growth was evaluated by cell counting, while morphology was assessed by light microscopy. Hemocompatibility was evaluated using a thrombin generation assay and a complement convertase assay. The foreign body reaction against poly(DLLA-ε-CL) nerve guides was investigated by examining toluidine blue stained sections. The in vitro degradation data showed that poly(DLLA-ε-CL) nerve guides do not swell, maintain their mechanical strength and flexibility for a period of about 8-10 weeks, and start to lose mass after about 10 weeks. Poly(DLLA-ε-CL) nerve guides were classified as noncytotoxic, as cytotoxicity tests demonstrated that cell morphology was not affected (CPII 0%). The thrombin generation assay and complement convertase assay indicated that the material is highly hemocompatible. The foreign body reaction against the biomaterial was mild with a light priming of the immunesystem. The results presented in this study demonstrate that poly(65/35(85/15 L/D) lactide-ε-caprolactone) nerve guides are biocompatible, and show good in vitro degradation characteristics, making these biodegradable nerve guides promising candidates for bridging peripheral nerve defects up to several centimeters. © 2003 Wiley Periodicals, Inc. AD - Department of Plastic Surgery, University Hospital Groningen, Hanzeplein 1, 9713 GZ Groningen, Netherlands Department of Medical Biology, Faculty of Medical Sciences, University of Groningen, Bloemsingel 10, 9712 KZ Groningen, Netherlands Polyganics BV, LJ Zielstraweg 1, 9713 GX Groningen, Netherlands Haemoprobe, LJ Zielstraweg 1, 9713 GX Groningen, Netherlands AU - Meek, M. F. AU - Jansen, K. AU - Steendam, R. AU - Van Oeveren, W. AU - Van Wachem, P. B. AU - Van Luyn, M. J. A. DB - Scopus DO - 10.1002/jbm.a.10157 IS - 1 KW - Cytotoxicity Hemocompatibility Implantation In vitro degradation Peripheral nerve guide M3 - Article N1 - Cited By :45 Export Date: 10 November 2020 PY - 2004 SP - 43-51 ST - In vitro degradation and biocompatibility of poly(DL-lactide-ε -caprolactone) nerve guides T2 - Journal of Biomedical Materials Research - Part A TI - In vitro degradation and biocompatibility of poly(DL-lactide-ε -caprolactone) nerve guides UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0346335848&doi=10.1002%2fjbm.a.10157&partnerID=40&md5=747171592ff2ce7ea06471f24629206d VL - 68 ID - 1635 ER - TY - JOUR AB - The in vitro cytotoxicity and in vivo biocompatibility of poly(propylene fumarate-co-ethylene glycol) [P(PF-co-EG)] hydrogels were assessed in order to investigate the influence of poly(ethylene glycol) molecular weight and copolymer composition. These materials have application as injectable cardiovascular implants; cytotoxicity due to leachable products, as well as inflammation caused by the biomaterial itself, may ultimately affect the biocompatibility of the implant. We utilized a 7-day in vitro cytotoxicity assay to quantify cell density and cellular proliferation in the presence of copolymer films. The copolymer films exhibited slight to moderate cytotoxicity toward cultured endothelial cells, showing 20-86% viability relative to controls. Cell viability increased with an increasing weight percent of PEG or, to a lesser extent, the molecular weight of PEG. In vivo biocompatibility was assessed using a cage implantation model over a 21-day time period. This system was used to characterize the local cellular and humoral inflammatory response in the surrounding exudate, as well as the size and density of macrophages adherent to the material itself. All copolymer formulations exhibited excellent biocompatibility relative to controls with no significant differences in total leukocyte count among the different formulations. The in vivo inflammatory reaction displayed normal wound healing over 21 days as shown by a progressive decrease in both leukocyte concentration and enzymatic activity. The surface coverage of the copolymer films remained relatively constant from 7 to 21 days. There were no cells larger than 0.003 mm2, which was previously shown to be the threshold value for foreign-body giant cells. These data suggest that P(PF-co-EG) hydrogels have potential for use as injectable biomaterials. The in vitro cytotoxicity and in vivo biocompatibility of poly(propylene fumarate-co-ethylene glycol) [P(PF-co-EG)] hydrogels were assessed in order to investigate the influence of poly(ethylene glycol) molecular weight and copolymer composition. These materials have application as injectable cardiovascular implants; cytotoxicity due to leachable products, as well as inflammation caused by the biomaterial itself, may ultimately affect the biocompatibility of the implant. We utilized a 7-day in vitro cytotoxicity assay to quantify cell density and cellular proliferation in the presence of copolymer films. The copolymer films exhibited slight to moderate cytotoxicity toward cultured endothelial cells, showing 20-86% viability relative to controls. Cell viability increased with an increasing weight percent of PEG or, to a lesser extent, the molecular weight of PEG. In vivo biocompatibility was assessed using a cage implantation model over a 21-day time period. This system was used to characterize the local cellular and humoral inflammatory response in the surrounding exudate, as well as the size and density of macrophages adherent to the material itself. All copolymer formulations exhibited excellent biocompatibility relative to controls with no significant differences in total leukocyte count among the different formulations. The in vivo inflammatory reaction displayed normal wound healing over 21 days as shown by a progressive decrease in both leukocyte concentration and enzymatic activity. The surface coverage of the copolymer films remained relatively constant from 7 to 21 days. There were no cells larger than 0.003 mm2, which was previously shown to be the threshold value for foreign-body giant cells. These data suggest that P(PF-co-EG) hydrogels have potential for use as injectable biomaterials. AD - Cox Lab. for Biomedical Engineering, Inst. of Biosci. and Bioengineering, Rice University, 6100 South Main Street, Houston, TX 77251-1892, United States Depts. Pathol., Biomed. Eng., M., Case Western Reserve University, Cleveland, OH 44106, United States AU - Suggs, L. J. AU - Shive, M. S. AU - Garcia, C. A. AU - Anderson, J. M. AU - Mikos, A. G. DB - Scopus DO - 10.1002/(SICI)1097-4636(199907)46:1<22::AID-JBM3>3.0.CO;2-R IS - 1 KW - Biocompatibility Cardiovascular stent Cytotoxicity Hydrogel Poly(ethylene glycol) Poly(propylene fumarate) Tissue engineering M3 - Article N1 - Cited By :104 Export Date: 10 November 2020 PY - 1999 SP - 22-32 ST - In vitro cytotoxicity and in vivo biocompatibility of poly(propylene fumarate-co-ethylene glycol) hydrogels T2 - Journal of Biomedical Materials Research TI - In vitro cytotoxicity and in vivo biocompatibility of poly(propylene fumarate-co-ethylene glycol) hydrogels UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032955467&doi=10.1002%2f%28SICI%291097-4636%28199907%2946%3a1%3c22%3a%3aAID-JBM3%3e3.0.CO%3b2-R&partnerID=40&md5=88dae1daa3b7554cda146928fa56610d VL - 46 ID - 1688 ER - TY - JOUR AB - The true extent of a tumor is difficult to visualize, during radiotherapy, using current modalities. In the present study, the safety and feasibility of a mixture of N-butyl cyanoacrylate and lipiodol (NBCA/Lip) was evaluated in order to investigate the optimal combination for application as a fiducial marker for radiotherapy. Four combinations of NBCA/Lip injection (1:1-0.1, 1:1-0.15, 1:3-0.1 and 1:3-0.15 ml) were injected into the subcutaneous tissue of BALB/c mice. The changes in gross histopathology, body weight, skin score, marker volume, neutrophil and macrophage counts were observed to analyze the effects of the different mixing ratios and injection volumes, in order to identify the best combination. Evaluation according to the International Organization for Standardization criteria was further conducted in order to test the biocompatibility of the mixture, including an acute systematic assay with mice, cytotoxicity with L929 fibroblasts and delayed-type hypersensitivity tests with guinea pigs and an intradermal test with rabbits. The results revealed that at the seventh week, 42 markers (42/48; 87.5%) were still visible using computed tomography (CT) imaging. No serious adverse effects were observed throughout the study period; however, the combination of 1:1-0.1 ml had the lowest body weight and worst skin score. A review of the histopathological reaction to NBCA/Lip revealed a combination of acute inflammation, chronic inflammation, granulation tissue, foreign-body reaction and fibrous capsule formation. The 1:1 NBCA combination ratio resulted in the most intense tissue repair reaction and a slower degradation rate of markers. In general, the combination of 1:3-0.15 ml had a better fusion with local tissue, maintained a stable imaging nodule on CT images for 7 weeks and the final biocompatibility test demonstrated its safety. Overall, the findings of the present study demonstrated NBCA/Lip as a safe and feasible fiducial marker, when using the 1:3-0.15 ml combination. AD - X. Meng, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, 440 Jiyan Road, Jinan, Shandong, China AU - Sun, L. C. AU - Su, Y. AU - Ding, X. C. AU - Xu, D. S. AU - Li, C. M. AU - Wang, L. AU - Li, W. L. AU - Sun, X. D. AU - Yu, J. M. AU - Meng, X. DB - Embase DO - 10.3892/ol.2020.11591 IS - 1 KW - collagen type 1 cotton seed oil cyanoacrylate gelatinase B interleukin 6 iodinated poppyseed oil ketamine animal experiment animal model animal tissue article ataxic gait biocompatibility body weight cell proliferation chronic inflammation computer assisted tomography controlled study cytotoxicity drug efficacy drug safety erythema evaluation study feasibility study human human tissue hypersensitivity image analysis image guided radiotherapy in vitro study in vivo study macrophage male mouse MTT assay neutrophil nonhuman subcutaneous tissue tissue repair upregulation LA - English M3 - Article N1 - L2006061173 2020-06-09 2020-07-08 PY - 2020 SN - 1792-1082 1792-1074 SP - 569-580 ST - In vitro and in vivo evaluation of the safety and efficacy of a novel liquid fiducial marker for image-guided radiotherapy T2 - Oncology Letters TI - In vitro and in vivo evaluation of the safety and efficacy of a novel liquid fiducial marker for image-guided radiotherapy UR - https://www.embase.com/search/results?subaction=viewrecord&id=L2006061173&from=export http://dx.doi.org/10.3892/ol.2020.11591 VL - 20 ID - 274 ER - TY - JOUR AB - Introduction: The major complications of stent implantation are restenosis and late stent thrombosis. PBMA polymers are used for stent coating because of their mechanical properties. We previously synthesized and characterized Dextran-graft-polybutylmethacrylate copolymer (Dex-PBMA) as a potential stent coating. In this study, we evaluated the haemocompatibility and biocompatibility properties of Dex-PBMA in vitro and in vivo. Methods: Here, we investigated: (1) the effectiveness of polymer coating under physiological conditions and its ability to release Tacrolimus®, (2) the capacity of Dex-PBMA to inhibit Staphylococcus aureus adhesion, (3) the thrombin generation and the human platelet adhesion in static and dynamic conditions, (4) the biocompatibility properties in vitro on human endothelial colony forming cells (ECFC) and on mesenchymal stem cells (MSC) and in vivo in rat models, and (5) we implanted Dex-PBMA and Dex-PBMA TAC coated stents in neointimal hyperplasia restenosis rabbit model. Results: Dex-PBMA coating efficiently prevented bacterial adhesion and release Tacrolimus®. Dex-PBMA exhibit haemocompatibility properties under flow and ECFC and MSC compatibility. In vivo, no pathological foreign body reaction was observed neither after intramuscular nor intravascular aortic implantation. After Dex-PBMA and Dex-PBMA TAC coated stents 30 days implantation in a restenosis rabbit model, an endothelial cell coverage was observed and the lumen patency was preserved. Conclusion: Based on our findings, Dex-PBMA exhibited vascular compatibility and can potentially be used as a coating for metallic coronary stents. © 2019 The Author(s). AD - INSERM, UMR-S1148, Laboratory for Vascular Translational Sciences, Hôpital Bichat, France Université Paris 13, Sorbonne Paris Cité, France Inserm, UMR-S1140, Paris, France Université Paris Descartes, Sorbonne Paris Cité, France AU - Delattre, C. AU - Velasquez, D. AU - Roques, C. AU - Pavon-Djavid, G. AU - Ollivier, V. AU - Lokajczyk, A. AU - Avramoglou, T. AU - Gueguen, V. AU - Louedec, L. AU - Caligiuri, G. AU - Jandrot-Perrus, M. AU - Boisson-Vidal, C. AU - Letourneur, D. AU - Meddahi-Pelle, A. DB - Scopus DO - 10.15171/bi.2019.04 IS - 1 KW - Animal model Biocompatibility Dextran Haemocompatibility In vitro Stent M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2019 SP - 25-36 ST - In vitro and in vivo evaluation of a dextran-graft-polybutylmethacrylate copolymer coated on CoCr metallic stent T2 - BioImpacts TI - In vitro and in vivo evaluation of a dextran-graft-polybutylmethacrylate copolymer coated on CoCr metallic stent UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85060479725&doi=10.15171%2fbi.2019.04&partnerID=40&md5=0775c6f8ae7386972528ff52e66cfced VL - 9 ID - 1044 ER - TY - JOUR AB - To reduce infection rates after mesh implantation antibiotic-coated meshes were designed. The aim of the study was to analyze biocompatibility and in vitro efficiency of a modified gentamicin-supplemented polyvinylidenfluoride mesh. Twenty rats were randomized to two groups (PVDF group and Genta group). Mesh material was implanted subcutaneously. Blood samples were taken to determine the gentamicin serum concentration. Seven and 90 days after mesh implantation, animals were euthanized. The inflammatory tissue response was characterized by analyzing the foreign body granuloma. Cellular immune response was analyzed by immunohistochemical investigations. The collagen type I/III ratio was estimated by crosspolarization microscopy. In vitro agar diffusion test, suspension test, and gentamicin release were characterized. Agar diffusion and suspension test showed efficient antibiotic effects of the mesh in vitro. Serum concentrations of gentamicin showed a peak value 1 h postoperatively with a decline within the next day. The total size of the granuloma was significantly smaller in the Genta group compared to the PVDF group at both points of time. Except of a short period of increased expression of CD68 in the Genta group after 7 days, no further difference was found analyzing cellular immune response. The collagen type I/III ratio was widely constant analyzing the two mesh types without significant differences comparing both mesh materials. A significantly decreased foreign body granuloma formation compared to the pure PVDF mesh group was found. In vitro analysis showed efficient antibiotic effects of the Gentamicin supplementation compared to the pure PVDF mesh. © 2012 WILEY PERIODICALS, INC. AD - Department of Surgery, RWTH Aachen, Germany Department of Applied Medical Engineering, Helmholtz Institute, RWTH Aachen, Germany AU - Klink, C. D. AU - Binnebösel, M. AU - Lambertz, A. AU - Alizai, H. P. AU - Roeth, A. AU - Otto, J. AU - Klinge, U. AU - Neumann, U. P. AU - Junge, K. DB - Scopus DO - 10.1002/jbm.a.34066 IS - 5 KW - abdominal wall hernia antibiotic coating collagen type I/III ratio gentamicin mesh repair PVDF M3 - Article N1 - Cited By :22 Export Date: 10 November 2020 PY - 2012 SP - 1195-1202 ST - In vitro and in vivo characteristics of gentamicin-supplemented polyvinylidenfluoride mesh materials T2 - Journal of Biomedical Materials Research - Part A TI - In vitro and in vivo characteristics of gentamicin-supplemented polyvinylidenfluoride mesh materials UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84859105516&doi=10.1002%2fjbm.a.34066&partnerID=40&md5=3136ac25cf4a823285a59a1feba4eb81 VL - 100 A ID - 1370 ER - TY - JOUR AD - Director: Quality of care, Gauteng Department of Health AN - 104143030. Language: English. Entry Date: 20130628. Revision Date: 20150819. Publication Type: Journal Article AU - Armstrong, S. DB - ccm DP - EBSCOhost IS - 2 KW - Retained Instruments Surgical Sponges Inpatients Female Pregnancy Adult Cesarean Section Surgical Count Procedure Perioperative Nursing Retained Instruments -- Complications Root Cause Analysis Adverse Health Care Event Documentation Surgical Wound Care Readmission Breast Feeding Obstetric Nursing Quality of Health Care N1 - case study. Journal Subset: Africa; Nursing; Peer Reviewed. PY - 2008 SN - 1607-6672 SP - 7-10 ST - Improving the quality of care - learning through case studies Retained abdominal swab T2 - Professional Nursing Today TI - Improving the quality of care - learning through case studies Retained abdominal swab UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104143030&site=ehost-live&scope=site VL - 12 ID - 776 ER - TY - JOUR AB - PURPOSE OF REVIEW: Gossypibomas are surgical sponges that are unintentionally left inside a patient during a surgical procedure. To improve this patient safety indicator, anesthesiologists will need to work with operating room personnel. This study's goal was to systematically review the literature on retained sponges to identify body location, time to discovery, methods for detection, and risk factors. RECENT FINDINGS: Two hundred and fifty-four gossypiboma cases (147 reports from the period 1963-2008) were identified via the National Library of Medicine's Medline and the Cochrane Library. Gossypibomas (mean patient age 49 years, range 6-92 years) were most commonly found in the abdomen (56%), pelvis (18%), and thorax (11%). Average discovery time equaled 6.9 years (SD 10.2 years) with a median (quartiles) of 2.2 years (0.3-8.4 years). The most common detection methods were computed tomography (61%), radiography (35%), and ultrasound (34%). Pain/irritation (42%), palpable mass (27%), and fever (12%) were the leading signs and symptoms, but 6% of cases were asymptomatic. Complications included adhesion (31%), abscess (24%), and fistula (20%). Risk factors were case specific (e.g. emergency) or related to the surgical environment (e.g. poor communication). Most gossypibomas occurred when the sponge count was falsely pronounced correct at the end of surgery. SUMMARY: More is being discovered about the patterns leading to a retained sponge. Multidisciplinary approaches and new technologies may help reduce this low frequency but clinically significant event. However, given the complexity of surgical care, eliminating retained sponges may prove elusive. AD - Stanford University School of Medicine, Stanford, California 94305-5640, USA. shuai@stanford.edu AN - 19390247 AU - Wan, W. AU - Le, T. AU - Riskin, L. AU - Macario, A. DA - Apr DO - 10.1097/ACO.0b013e328324f82d DP - NLM ET - 2009/04/25 IS - 2 KW - Abdomen Adolescent Adult Aged Aged, 80 and over Child Female Foreign Bodies/diagnostic imaging/*etiology Humans Incidence Male Middle Aged Pelvis Radiography Risk Factors Surgical Sponges/*statistics & numerical data Ultrasonography Young Adult LA - eng N1 - 1473-6500 Wan, Wenshuai Le, Thuan Riskin, Loren Macario, Alex Journal Article Research Support, Non-U.S. Gov't Review Systematic Review United States Curr Opin Anaesthesiol. 2009 Apr;22(2):207-14. doi: 10.1097/ACO.0b013e328324f82d. PY - 2009 SN - 0952-7907 SP - 207-14 ST - Improving safety in the operating room: a systematic literature review of retained surgical sponges T2 - Curr Opin Anaesthesiol TI - Improving safety in the operating room: a systematic literature review of retained surgical sponges VL - 22 ID - 91 ER - TY - JOUR AB - OBJECTIVE: To reduce the incidence of retained vaginal swabs and near misses. STUDY DESIGN: A review of previous retained swab incidents and near misses in a large maternity unit identified handovers and transfers as a key point of vulnerability. Interventions were introduced to improve communication at handover from the delivery suite to theatre and from theatre to the high dependency unit. Process data was collected to monitor compliance. The outcome measures were the incidence of retained swab never events and the incidence of near misses. Chi-squared analysis was used to test the significance of the results. RESULTS: For transfers from delivery suite to theatre, verbal handover significantly increased from 28.8% to 75.6% (p<0.0001), and written handover significantly increased from 4.4% to 62.9% (p<0.0001). There were 291 transfers to theatre post-intervention: in 88 (30.2%) of these transfers a vaginal swab was already in situ. In 70/88 (79.5%) of cases the presence of the swab was communicated to theatre staff in three ways (verbally, written and transfer of opened swab packets) according to the new policy. In the post-intervention period there were 56 women transferred from theatre to the high-dependency unit with a vaginal pack in situ: 52 (92.9%) of these women had a sticker in place serving as a constant reminder of the presence of the vaginal pack to staff. Following a baseline of four near misses in two months, there has been only one near miss in the 15 months since the interventions were implemented, (33.3% vs. 1.1%, p<0.0001). There have been no retained swab incidents since the project commenced. CONCLUSIONS: Simple interventions to improve communication at handover and transfer can reduce the incidence of retained vaginal swabs and near misses. Further work is needed to raise the profile of swab counting in maternity settings: swab counting needs to be the responsibility of all disciplines, not just the responsibility of theatre staff. AD - Patient Safety Collaborative, Oxford Academic Health Science Network, Oxford, United Kingdom; Maternity Services, Oxford University Hospitals NHS Trust, Oxford, United Kingdom. Electronic address: Katie.Lean@oxfordahsn.org. Patient Safety Collaborative, Oxford Academic Health Science Network, Oxford, United Kingdom; Department of Experimental Psychology, University of Oxford, Oxford, United Kingdom. AN - 29172067 AU - Lean, K. AU - Page, B. F. AU - Vincent, C. DA - Jan DO - 10.1016/j.ejogrb.2017.11.006 DP - NLM ET - 2017/11/25 KW - *Communication Delivery, Obstetric/*standards Female Humans Medical Errors/*prevention & control *Patient Handoff *Quality of Health Care Communication Handover Maternity Never event Retained foreign objects Swabs LA - eng N1 - 1872-7654 Lean, Katie Page, Bethan F Vincent, Charles Journal Article Ireland Eur J Obstet Gynecol Reprod Biol. 2018 Jan;220:50-56. doi: 10.1016/j.ejogrb.2017.11.006. Epub 2017 Nov 9. PY - 2018 SN - 0301-2115 SP - 50-56 ST - Improving communication at handover and transfer reduces retained swabs in maternity services T2 - Eur J Obstet Gynecol Reprod Biol TI - Improving communication at handover and transfer reduces retained swabs in maternity services VL - 220 ID - 202 ER - TY - JOUR AB - Hypothesis/Aim of study:The american Food and Drug Administration (FDA) Issued a warning concerning the application of alloplastic materials for thesurgical treatment of female Incontinence and prolapse reporting more than 1000 severe adverse events associated with theused materials.Special surgical training together with the management of risk and AE's are recommended [1, 2]. The Improvement of thebiocompatibility coating foreign materials with e.g. autologous substances seems to be mandatory and was performed In an Invitrosetting using autologous plasma for the coating of meshs.Material and Methods:In order to answer the question whether coating of alloplastic materials with autologous material can lead to Improvedbiocompatibility, the following study approach was established:12 patients were Included. Written Informed consent of each patient was obligatory prior to the start of the procedure. 10ml ofblood, plasma and serum of each patient were preserved. Myoblasts, endothelial cells and fibroblasts of each patient werecultivated separately. Cell count and growth are comparable In all approaches within a test duration of 6 weeks.Immunohistochemical and microscopic evaluation of cell count and adherence Is performed considering the chosen coating forthe alloplastic material.Results:The In vitro analyses are Independent from gender and Individual patient features.Regarding tissue specifity different cell growth can de defined In favour of fibroblasts:fibroblasts > myoblasts > endothelial cells. Improved cell adhesion Is found on alloplastic meshs covered with autologousplasma compared to non- covered meshs. This finding Includes all types of cells being tested. A covering of meshs with serumor collagen seems to be of disadvantage. Looking at the Intensity of cell adhesion on the different meshs the following rankingcan be disposed:1. TFT Motifmesh ®, ProxyBiomedical2. Dynamesh®, FEG Textiltechnik3. Surgimesh ®, Aspide Medical, Resorba4. PDS Plate ®, Johnson & Johnson5. Mersilene Band, Johnson & Johnson6. Vitamesh ®, ProxyBiomedical7. Vicryl Band, Johnson & Johnson8. TiLoop ®, PFMCell adhesion on the following alloplastic materials could be verified neither In the uncovered nor In the covered approach:Ethisorb Patch ®, EthiconProceed surgical mesh ®, EthiconCollagenmeshResodont mesh ®, ResorbaParasorb mesh ®, ResorbaDualmesh®, Fa.GoreMycromesh®, Fa.GorePCL scaffoldAdVance male sling ®, AMSSeratim®, Serag-Wiessner Interpretation of results:Cell adhesion to the tested alloplastic materials regarding cells of the pelvic floor Is Insufficient. This observation may explainthe occurrence of foreign-body reaction and missing Integration of alloplastic materials Into the pelvic floor.Concluding message:Coating of meshs with autologous plasma results In an Improvement of the biocompatibility of alloplastic materials. AD - C. Eimer, Lukas Hospital, Germany AU - Eimer, C. AU - Gerullis, H. AU - Bagner, J. AU - Lammers, B. AU - Theuerkauf, I. AU - Ramon, A. AU - Otto, T. DB - Embase DO - 10.1007/s00192-011-1480-6 KW - collagen polyethylene terephthalate polyglactin tissue injury incontinence biocompatibility hernia society continence surgery human patient fibroblast cell adhesion myoblast endothelium cell blood autotransfusion cell count female surgical training risk foreign body informed consent procedures serum in vitro study gender tissues cell growth adhesion surgical equipment male pelvis floor foreign body reaction pelvis Food and Drug Administration plasma LA - English M3 - Conference Abstract N1 - L70637667 2012-01-13 PY - 2011 SN - 0937-3462 SP - S1568-S1569 ST - Improvement of the biocompatibility of alloplastic materials for surgery due to hernia, incontinence and organ prolapse T2 - International Urogynecology Journal and Pelvic Floor Dysfunction TI - Improvement of the biocompatibility of alloplastic materials for surgery due to hernia, incontinence and organ prolapse UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70637667&from=export http://dx.doi.org/10.1007/s00192-011-1480-6 VL - 22 ID - 540 ER - TY - JOUR AU - Greaves, J. DB - Scopus IS - 7 M3 - Article N1 - Export Date: 10 November 2020 PY - 1981 SP - 19-22 ST - Implementing counts in the operating room T2 - NATNews TI - Implementing counts in the operating room UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019587927&partnerID=40&md5=2fdc8ce6f2c0da7901e2a4018dac4b2d VL - 18 ID - 1765 ER - TY - JOUR AB - Retention of a surgical item is a preventable event that can result in patient injury. AORN's "Recommended practices for prevention of retained surgical items" emphasizes the importance of using a multidisciplinary approach for prevention. Procedures should include counts of soft goods, needles, miscellaneous items, and instruments, and efforts should be made to prevent retention of fragments of broken devices. If a count discrepancy occurs, the perioperative team should follow procedures to locate the missing item. Perioperative leaders may consider the use of adjunct technologies such as bar-code scanning, radio-frequency detection, and radio-frequency identification. Ambulatory and hospital patient scenarios are included to exemplify appropriate strategies for preventing retained surgical items. AD - The William W. Backus Hospital, Norwich, CT, USA. AN - 22283912 AU - Goldberg, J. L. AU - Feldman, D. L. DA - Feb DO - 10.1016/j.aorn.2011.11.010 DP - NLM ET - 2012/01/31 IS - 2 KW - Foreign Bodies/*prevention & control Humans Medical Errors/*prevention & control Perioperative Nursing/methods/*standards *Practice Guidelines as Topic Surgical Instruments Surgical Procedures, Operative/*nursing/standards Surgical Sponges LA - eng N1 - 1878-0369 Goldberg, Judith L Feldman, David L Journal Article United States AORN J. 2012 Feb;95(2):205-16; quiz 217-9. doi: 10.1016/j.aorn.2011.11.010. PY - 2012 SN - 0001-2092 SP - 205-16; quiz 217-9 ST - Implementing AORN recommended practices for prevention of retained surgical items T2 - Aorn j TI - Implementing AORN recommended practices for prevention of retained surgical items VL - 95 ID - 121 ER - TY - JOUR DB - Medline DO - 10.1002/aorn.12971 IS - 2 KW - classification human interview medical error prevention and control procedures surgical sponge total quality management LA - English M3 - Article N1 - L630775525 2020-02-05 2020-11-09 PY - 2020 SN - 1878-0369 SP - P11-P13 ST - Implementing a "visualize and verify" process for the surgical sponge count T2 - AORN journal TI - Implementing a "visualize and verify" process for the surgical sponge count UR - https://www.embase.com/search/results?subaction=viewrecord&id=L630775525&from=export http://dx.doi.org/10.1002/aorn.12971 VL - 111 ID - 288 ER - TY - JOUR AB - Background: Compliance with the World Health Organization (WHO) surgical safety checklist may reduce preventable adverse events. However, compliance may be difficult to implement in Thailand. This study was conducted to examine compliance with the WHO checklist at a Thai university hospital. Methods: A descriptive study was conducted among 4,340 patients undergoing surgery in nine departments from March to August 2009. The compliance rates were computed. Results: The highest compliance rate (91.4%) during the sign-in period was with patients' confirmation of their identity, operative site, procedure, and consent. However, only 19.4% of the surgical sites were marked. In the time-out period, surgical teams had introduced themselves by name and role in 79% of the operations; and in 95.7% of the cases, the patient's name, the incision site, and the procedure had been confirmed. Antibiotic prophylaxis had been given within 60 min before the incision in 71% of the cases. For 83% of the operations, the surgeons reviewed crucial events whereas only 78.4% were reviewed by the anesthetists. Sterility had been confirmed by the operating room nurses for every patient, but the essential imaging was displayed at a rate of only 64.4%. In the sign-out period, nurses correctly confirmed the name of the procedure orally in 99.5% of the cases. Instrument, sponge, and needle counts were completed and the specimen was labeled in most cases, 96.8% and 97.6%, respectively. Equipment-related problems were identified in 4.4% of the cases, and 100% of them were addressed. The surgeon, anesthetist, and nurse reviewed the key concerns for recovery and management of the patient at the rate of 85.1%. Conclusions: The WHO checklist can be implemented in a developing country. However, compliance with some items was extremely low, reflecting different work patterns and cultural norms. Additional education and enforcement of checklist use is needed to improve compliance. © 2012, Mary Ann Liebert, Inc. AD - N. Kasatpibal, Faculty of Nursing, Chiang Mai University, Chiang Mai 50200, Thailand AU - Kasatpibal, N. AU - Senaratana, W. AU - Chitreecheur, J. AU - Chotirosniramit, N. AU - Pakvipas, P. AU - Junthasopeepun, P. DB - Embase Medline DO - 10.1089/sur.2011.043 IS - 1 KW - anesthesist antibiotic prophylaxis article checklist female health care planning human imaging incision informed consent major clinical study male needle nurse operating room personnel practice guideline priority journal safety surgeon surgery surgical equipment surgical safety checklist surgical sponge university hospital World Health Organization LA - English M3 - Article N1 - L364416620 2012-03-20 PY - 2012 SN - 1096-2964 1557-8674 SP - 50-56 ST - Implementation of the world health organization surgical safety checklist at a university hospital in Thailand T2 - Surgical Infections TI - Implementation of the world health organization surgical safety checklist at a university hospital in Thailand UR - https://www.embase.com/search/results?subaction=viewrecord&id=L364416620&from=export http://dx.doi.org/10.1089/sur.2011.043 VL - 13 ID - 524 ER - TY - JOUR AB - BACKGROUND: Retained sponges (gossypiboma) following vaginal delivery are an uncommon occurrence. Although significant morbidity from such an event is unlikely, there are many reported adverse effects, including symptoms of malodorous discharge, loss of confidence in providers and the medical system, and legal claims. OBJECTIVE: To report a protocol intended to reduce the occurrence of retained sponges following vaginal delivery. METHODS: After identification of limitations with existing delivery room protocols, we developed a sponge count protocol to reduce occurrence of retained vaginal sponges. We report our experience at Naval Medical Center Portsmouth, a large tertiary care military treatment facility with our efforts to implement a sponge count protocol to reduce retained sponges following vaginal delivery. CONCLUSIONS: With appropriate pre-implementation training, protocols which incorporate post-delivery vaginal sweep and sponge counts are well accepted by the health care team and can be incorporated into the delivery room routine. AD - Department of Obstetrics and Gynecology, Naval Medical Center Portsmouth, 620 John Paul Jones Circle, Portsmouth, VA 23708, USA. AN - 21702393 AU - Lutgendorf, M. A. AU - Schindler, L. L. AU - Hill, J. B. AU - Magann, E. F. AU - O'Boyle, J. D. DA - Jun DO - 10.7205/milmed-d-10-00438 DP - NLM ET - 2011/06/28 IS - 6 KW - *Clinical Protocols *Delivery, Obstetric Female Foreign Bodies/*prevention & control Humans Medical Errors/*prevention & control Pregnancy Surgical Sponges/*adverse effects Vagina/surgery LA - eng N1 - Lutgendorf, Monica A Schindler, Lynnett L Hill, James B Magann, Everett F O'Boyle, John D Journal Article England Mil Med. 2011 Jun;176(6):702-4. doi: 10.7205/milmed-d-10-00438. PY - 2011 SN - 0026-4075 (Print) 0026-4075 SP - 702-4 ST - Implementation of a protocol to reduce occurrence of retained sponges after vaginal delivery T2 - Mil Med TI - Implementation of a protocol to reduce occurrence of retained sponges after vaginal delivery VL - 176 ID - 109 ER - TY - JOUR AB - The response of osseous tissue to the implantation of sepiolite-collagen complexes has been studied. Sepiolite, sepiolite-collagen complex and 0.5% glutaraldehyde-treated sepiolite-collagen complex were implanted in created circular defects in rat calvaria. The tissue reactions were analysed using light, transmission and scanning electron microscopies. The patterns of bone growth were radiographically analysed and the bone activity was indirectly quantified by using a point-count method. The reaction against the three implanted materials is characteristic of a foreign body reaction with abundant macrophages and giant cells. Implanted products have been detected in macrophages, which suggest the involvement of phagocytosis in the resorptive process. Bone grew at the implantation sites originating excrescences or sometimes a thin bridge at the defect margins. The studied materials, after implantation in contact with bone tissue, did not produce any toxic effect or necrosis, allowing bone activity. © 1995. AD - Departamento de Medicina y Cirugia Bucofacial (Periodoncia), Facultad de Odontología, Universidad Complutense, 28040 Madrid, Spain Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense, 28040 Madrid, Spain Departamento de Cirugía y Especialidades Médico-Quirúrgicas, Escuela de Estomatologia, Universidad de Oviedo, Oviedo, Spain AU - Herrera, JosI AU - Olmo, N. AU - Turnay, J. AU - Sicilia, A. AU - Bascones, A. AU - Gavilanes, JosG AU - Lizarbe, M. DB - Scopus DO - 10.1016/0142-9612(95)93860-G IS - 8 KW - collagen-based biomaterials composites in vivo implantation Sepiolite-collagen complexes M3 - Article N1 - Cited By :17 Export Date: 10 November 2020 PY - 1995 SP - 625-631 ST - Implantation of sepiolite-collagen complexes in surgically created rat calvaria defects T2 - Biomaterials TI - Implantation of sepiolite-collagen complexes in surgically created rat calvaria defects UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029048713&doi=10.1016%2f0142-9612%2895%2993860-G&partnerID=40&md5=087e18df483293d417b5afa649b7389a VL - 16 ID - 1724 ER - TY - JOUR AB - Accidentally swallowed dentures can lead to severe complications in the gastrointestinal tract. Therefore, an early detection and an effective therapeutic management are important. In the era of advanced endoscopy, though the primary treatment of an impacted foreign body in the oesophagus is an endoscopic removal, a primary surgical treatment is advised for dentures with sharp hooks. Also, a prolonged impaction of dentures with sharp hooks leads to an increase in the complication rates. We are reporting a case of accidentally swallowed denture. After the diagnosis of an impacted denture was made, upper GI endoscopy revealed that an endoscopic removal was not feasible and thus, a late surgical removal was performed in the form of a transhiatal oesophagectomy and reconstruction. This case highlights the importance of an early and preferred treatment in the form of a controlled surgical intervention as compared to an endoscopic extraction for patients with impacted dentures with sharp hooks. AD - Department of General Surgery, Guru Gobind Singh Medical College and Hospital, Sadiq Road, Faridkot-151 203, Punjab, India AU - Singh, P. AU - Singh, A. AU - Kant, P. AU - Zonunsanga, B. AU - Singh Kuka, A. DB - Scopus DO - 10.7860/JCDR/2013/5337.2976 IS - 5 KW - Denture with sharp hooks Impacted denture Impacted foreign body in the oesophagus Oesophagectomy M3 - Article N1 - Cited By :9 Export Date: 10 November 2020 PY - 2013 SP - 919-920 ST - An impacted denture in the oesophagus- an endoscopic or a surgical emergency-a case report T2 - Journal of Clinical and Diagnostic Research TI - An impacted denture in the oesophagus- an endoscopic or a surgical emergency-a case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84877132772&doi=10.7860%2fJCDR%2f2013%2f5337.2976&partnerID=40&md5=4ceb89ffdcdbf25ef4d58fac959629fa VL - 7 ID - 1319 ER - TY - JOUR AB - OBJECTIVES: The aim of the study was to compare retained surgical item (RSI) rates for 137 Veterans Health Administration Surgery Programs with and without surgical count technology and the root cause analysis (RCA) for soft good RSI events between October 1, 2009 and December 31, 2016. A 2017 survey identified 46 programs to have independently acquired surgical count technology. METHODS: Retained surgical item rates were calculated by the sum of events (sharp, soft good, instrument) divided by the total procedures performed. The RCAs for RSI events were analyzed using codebooks for procedure type/location and root cause characterization. RESULTS: One hundred twenty-four RSI events occurred in 2,964,472 procedures for an overall RSI rate of 1/23,908 procedures. The RSI rates for 46 programs with surgical count technology were significantly higher in comparison with 91 programs without a surgical count technology system (1/18,221 versus 1/30,593, P = 0.0026). The RSI rates before and after acquiring the surgical count technology were not significantly different (1/17,508 versus 1/18,673, P = 0.8015). Root cause analyses for 42 soft good RSI events identified multiple associated disciplines (general surgery 26, urology 5, cardiac 4, neurosurgery 3, vascular 2, thoracic 1, gynecology 1) and locations (abdomen 26, thorax 7, retroperitoneal 4, paraspinal 2, extremity 1, pelvis 1, and head/neck 1). Human factors (n = 24), failure of policy/procedure (n = 21), and communication (n = 19) accounted for 64 (65%) of the 98 root causes identified. CONCLUSIONS: Acquisition of surgical count technology did not significantly improve RSI rates. Soft good RSI events are associated with multiple disciplines and locations and the following dominant root causes: human factors, failure to follow policy/procedure, and communication. AD - From the Veterans Health Administration (VHA) National Center for Patient Safety, The George Washington University, Washington, District of Columbia. VHA National Center for Patient Safety, Ann Arbor, Michigan. VHA National Surgery Office, Washington, District of Columbia. AN - 32217934 AU - Gunnar, W. AU - Soncrant, C. AU - Lynn, M. M. AU - Neily, J. AU - Tesema, Y. AU - Nylander, W. DA - Mar 24 DO - 10.1097/pts.0000000000000656 DP - NLM ET - 2020/03/29 LA - eng N1 - 1549-8425 Gunnar, William Soncrant, Christina Lynn, Marilyn M Neily, Julia Tesema, Yohannes Nylander, William Journal Article United States J Patient Saf. 2020 Mar 24. doi: 10.1097/PTS.0000000000000656. PY - 2020 SN - 1549-8417 ST - The Impact of Surgical Count Technology on Retained Surgical Items Rates in the Veterans Health Administration T2 - J Patient Saf TI - The Impact of Surgical Count Technology on Retained Surgical Items Rates in the Veterans Health Administration ID - 244 ER - TY - JOUR AB - OBJECTIVE: The impact of staff turnover during cardiac procedures is unknown. Accurate inventory of sharps (needles/blades) requires attention by surgical teams, and sharp count errors result in delays, can lead to retained foreign objects, and may signify communication breakdown. We hypothesized that increased team turnover raises the likelihood of sharp count errors and may negatively affect patient outcomes. METHODS: All cardiac operations performed at our institution from May 2011 to March 2016 were reviewed for sharp count errors from a prospectively maintained database. Univariate and multivariable analyses were performed. RESULTS: Among 7264 consecutive cardiac operations, sharp count errors occurred in 723 cases (10%). There were no retained sharps detected by x-ray in our series. Sharp count errors were lower on first start cases (7.7% vs 10.7%, P < .001). Cases with sharp count errors were longer than those without (7 vs 5.7 hours, P < .001). In multivariable analysis, factors associated with an increase in sharp count errors were non-first start cases (odds ratio [OR], 1.3; P = .006), weekend cases (OR, 1.6; P < .004), more than 2 scrub personnel (3 scrubs: OR, 1.3; P = .032; 4 scrubs: OR, 2; P < .001; 5 scrubs: OR, 2.4; P = .004), and more than 1 circulating nurse (2 nurses: OR, 1.9; P < .001; 3 nurses: OR, 2; P < .001; 4 nurses: OR, 2.4; P < .001; 5 nurses: OR, 3.1; P < .001). Sharp count errors were associated with higher rates of in-hospital mortality (OR, 1.9; P = .038). CONCLUSIONS: Sharp count errors are more prevalent with increased team turnover and during non-first start cases or weekends. Sharp count errors may be a surrogate marker for other errors and thus increased mortality. Reducing intraoperative team turnover or optimizing hand-offs may reduce sharp count errors. AD - Division of Cardiac Surgery, Massachusetts General Hospital, Boston, Mass. Electronic address: jpbloom@mgh.harvard.edu. Division of Cardiac Surgery, Massachusetts General Hospital, Boston, Mass. Perioperative Services Administration, Massachusetts General Hospital, Boston, Mass. AN - 31928826 AU - Bloom, J. P. AU - Moonsamy, P. AU - Gartland, R. M. AU - O'Malley, C. AU - Tolis, G., Jr. AU - Villavicencio-Theoduloz, M. A. AU - Burkhardt, C. AU - Dunn, P. AU - Sundt, T. M. AU - D'Alessandro, D. A. DA - Nov 30 DO - 10.1016/j.jtcvs.2019.11.051 DP - NLM ET - 2020/01/14 KW - cardiac surgery operating room staff turnover patient safety sharps inventory LA - eng N1 - 1097-685x Bloom, Jordan P Moonsamy, Philicia Gartland, Rajshri M O'Malley, Catherine Tolis, George Jr Villavicencio-Theoduloz, Mauricio A Burkhardt, Carolyn Dunn, Peter Sundt, Thoralf M D'Alessandro, David A Journal Article United States J Thorac Cardiovasc Surg. 2019 Nov 30:S0022-5223(19)34022-X. doi: 10.1016/j.jtcvs.2019.11.051. PY - 2019 SN - 0022-5223 ST - Impact of staff turnover during cardiac surgical procedures T2 - J Thorac Cardiovasc Surg TI - Impact of staff turnover during cardiac surgical procedures ID - 239 ER - TY - JOUR AB - The aim of the study was to analyze the acute inflammatory response after implantation of a heavyweight mesh of polypropylene (PP) compared with a composite mesh of light PP and polyglactin 910 (PG) in patients undergoing inguinal hernioplasty. A total of 30 male patients with inguinal hernia were included in the study and divided into 2 groups (PP and PP-PG) according to the mesh used. Changes of leukocytes, cytokines, growth factors, and acute phase proteins were evaluated in the sera. Leukocytes and acute phase proteins were significantly increased postoperatively in both groups, and the values were slightly higher in the PP group. Cytokine levels were significantly increased postoperatively in both groups; a slight increase was observed in the PP-PG group, especially for the proinflammatory cytokine. Growth factors decreased significantly in both groups immediately after surgery. The authors found that the use of the mesh is a stimulator of inflammatory response, and the 2 types of mesh induce a similar inflammatory response. © The Author(s) 2010. AD - Department of Surgical and Oncological Science, University of Palermo, via Liborio Giuffrè no 5, Palermo, Italy Division of Clinical Pathology, V. Cervello Hospital, Palermo, Italy AU - Di Vita, G. AU - Patti, R. AU - Barrera, T. AU - Arcoleo, F. AU - Ferlazzo, V. AU - Cillari, E. DB - Scopus DO - 10.1177/1553350610371334 IS - 3 KW - hernioplasty inflammatory response inguinal hernia mesh polyglactin 910 polypropylene M3 - Article N1 - Cited By :10 Export Date: 10 November 2020 PY - 2010 SP - 229-235 ST - Impact of heavy polypropylene mesh and composite light polypropylene and polyglactin 910 on the inflammatory response T2 - Surgical Innovation TI - Impact of heavy polypropylene mesh and composite light polypropylene and polyglactin 910 on the inflammatory response UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77956247521&doi=10.1177%2f1553350610371334&partnerID=40&md5=e01fce356d28e0a3d373b8e64e7f48b2 VL - 17 ID - 1451 ER - TY - JOUR AB - Over the past decade, hernia surgery has undergone a considerable transformation with the use of prosthetic materials. The most used polypropylene meshes induce a rapid acute inflammatory response followed by chronic foreign body reaction. Many factors influence this response such as density, size, physical characteristics, different texture and porosity of each biomaterial. The aim of this study is to assess whether the implant of monofilament or multifilament meshes, in the inguinal hernioplasty, determine a different inflammatory response. Thirty-two male patients were included in the study and were randomly divided into two groups. In the first group (MO) inguinal hernioplasty was performed using monofilament polypropylene mesh, while in the second one (MU) multifilament prosthesis was used. Peripheral venous blood samples were collected 24 hours before surgery and then 6, 24, 48 and 168 hours post-operatively. Modifications in leukocyte count, C-reactive protein (CRP), alpha-1 antitrypsin (alpha1-AT), interleukin (IL)-1, IL-6, IL-1 ra and IL-10 serum levels were recorded at all sampling times. We present evidence that serum levels of CRP, (alpha1-AT), leukocytes and cytokines were significantly increased post-operatively in both groups, returning to basal values 168 hours afterwards. In particular, the production of all pro-inflammatory mediators was higher in the MU group, whereas the anti-inflammatory cytokine (IL-10, IL-1ra) production was higher in MO patients. Our results indicate that polypropylene multifilament mesh allows a higher intense acute inflammatory response as compared to monofilament mesh implantation. AD - Department of Surgical and Oncologic Science, Division of General Surgery, University of Palermo, Palermo, Italy. divitagaetano@libero.it AN - 18336747 AU - Di Vita, G. AU - Patti, R. AU - Sparacello, M. AU - Balistreri, C. R. AU - Candore, G. AU - Caruso, C. DA - Jan-Mar DO - 10.1177/039463200802100123 DP - NLM ET - 2008/03/14 IS - 1 KW - Adult C-Reactive Protein/analysis Cytokines/blood Foreign-Body Reaction/etiology Hernia, Inguinal/*surgery Humans Inflammation/*etiology Leukocyte Count Male Middle Aged Pain, Postoperative/drug therapy Polypropylenes/*adverse effects Surgical Mesh/*adverse effects alpha 1-Antitrypsin/blood LA - eng N1 - Di Vita, G Patti, R Sparacello, M Balistreri, C R Candore, G Caruso, C Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't England Int J Immunopathol Pharmacol. 2008 Jan-Mar;21(1):207-14. doi: 10.1177/039463200802100123. PY - 2008 SN - 0394-6320 (Print) 0394-6320 SP - 207-14 ST - Impact of different texture of polypropylene mesh on the inflammatory response T2 - Int J Immunopathol Pharmacol TI - Impact of different texture of polypropylene mesh on the inflammatory response VL - 21 ID - 76 ER - TY - JOUR AB - The immune response against biomaterials in tissue-engineered constructs could potentially worsen the outcome of tissue regeneration, but immunological reactions between host and donor in tissue-engineered constructs remain to be clarified. In the present study, we syngenically transplanted tissue-engineered cartilage constructs consisting of C57BL/6 mice auricular chondrocytes and poly-l-lactic acid scaffolds (MW:200,000) into EGFP transgenic mice of C57BL/6 background, and evaluated the response by the localization of donor-derived and host-derived cells, the latter of which were distinguished by the presence of EGFP. While donor-derived cells constituted the areas of regenerated cartilage, host-derived cells were increased in number for the initial two weeks, and then decreased and excluded to non-cartilage areas thereafter. Furthermore, EGFP positivity was mostly co-localized with that of F4/80, suggesting most of the host-derived cells in the tissue-engineered constructs could be macrophages. Immunohistochemical staining of the tissue-engineered cartilage constructs revealed expression of factors related to immune privilege in chondrocytes, such as macrophage migration inhibitory factor (MIF), fas ligand (FasL) and others. Co-culture of chondrocytes and macrophages in vitro increased the expression of MIF and FasL in the chondrocytes, suggesting that chondrocytes in tissue-engineered cartilage constructs could regulate the actions of host-derived macrophages by expressing factors related to immune privilege. © 2009 Elsevier Ltd. All rights reserved. AD - Department of Cartilage and Bone Regeneration (Fujisoft), Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo, 113-8655, Japan Division of Tissue Engineering, The University of Tokyo Hospital, Hongo 7-3-1, Bunkyo-ku, Tokyo, 113-8655, Japan AU - Fujihara, Y. AU - Takato, T. AU - Hoshi, K. DB - Scopus DO - 10.1016/j.biomaterials.2009.10.053 IS - 6 KW - Cartilage tissue engineering Foreign body response Immune response Immunomodulation Polylactic acid Scaffold M3 - Article N1 - Cited By :35 Export Date: 10 November 2020 PY - 2010 SP - 1227-1234 ST - Immunological response to tissue-engineered cartilage derived from auricular chondrocytes and a PLLA scaffold in transgenic mice T2 - Biomaterials TI - Immunological response to tissue-engineered cartilage derived from auricular chondrocytes and a PLLA scaffold in transgenic mice UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-72149112742&doi=10.1016%2fj.biomaterials.2009.10.053&partnerID=40&md5=0f947de5fc3fb760cbe64dc076aeae10 VL - 31 ID - 1471 ER - TY - JOUR AB - The influence of remote removal of sacculus rotundus on humoral and cell mediated immunologic response in rabbits was studied. Ability to synthesize precipitins was only slightly impaired, but at the same time the numbers of PF cells were very distinctly reduced. Skin allografts 1-2 yr after the operation survived for somewhat longer periods; the reaction to tuberculin was entirely abolished and the course of allergic encephalitis was entirely suppressed. Removal of the sacculus rotundus in mature animals weakens immunologic reactivity of both classic types. This may be a result of cooperation of the thymus dependent and bursa dependent systems in inducing humoral as well as cell mediated immune reactions. AD - Dept. Immunopharmacol., Inst. Immunol. Exp. Ther., Pol. Acad. Sci., Wroclaw, Poland AU - Gieldanowski, J. AU - Blaszczyk, B. AU - Teodorczyk, J. DB - Scopus IS - 2 M3 - Article N1 - Export Date: 10 November 2020 PY - 1974 SP - 199-206 ST - Immunologic reactivity in rabbits remotely deprived of the Sacculus rotundus T2 - Archivum Immunologiae et Therapiae Experimentalis TI - Immunologic reactivity in rabbits remotely deprived of the Sacculus rotundus UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0016206602&partnerID=40&md5=9655ea434483eedf0d6a0a83deddb598 VL - 22 ID - 1778 ER - TY - JOUR AB - Metallic orthopaedics implants are composed of elements that are known to be skin sensitizers in the general population. In this study, we analyzed the cells of perivascular infiltration in the tissue adjacent to titanium (n = 23) and steel (n = 8) implants after explantation of the metals by immunohistochemical methods. The following panel of monoclonal antibodies were used as parameters: CD 1a (Langerhans cells), CD 4 (T-helper cells), CD 8 (T-suppressor cells), CD 11c (monocytes and macrophages), CD 45 RO (memory cells), CD 45 RA (naive cells), eosinophil cationic proteins (ECP), neutrophil elastase, and HLA-DR. The number of perivascular total cells did not differ significantly. All cells were identified in both metal subgroups, but a statistical difference was not seen in the above-mentioned parameters. We conclude that sensitization to metals is possible in the tissue adjacent to steel and titanium implants, because all cells which play an important role in allergic delayed-type hypersensitivity (type IV) reactions are present. This phenomenon may be called a 'pre-sensitization' phase, because no sensitization or allergic reactions were seen in our cases. Second, in the present study, a statistical difference was not seen in the number of infiltrate cells in the tissue adjacent to steel compared with titanium implants. AD - Department of Dermatology and Allergy, Biederstein, Technical University Munich, Germany Department of Trauma Surgery, University Regensburg, Germany AU - Thewes, M. AU - Kretschmer, R. AU - Gfesser, M. AU - Rakoski, J. AU - Nerlich, M. AU - Borelli, S. AU - Ring, J. DB - Scopus DO - 10.1007/s004020000230 IS - 4 KW - Immunohistochemistry Steel implant Titanium implant M3 - Article N1 - Cited By :26 Export Date: 10 November 2020 PY - 2001 SP - 223-226 ST - Immunohistochemical characterization of the perivascular infiltrate in tissues adjacent to stainless steel implants compared with titanium implants T2 - Archives of Orthopaedic and Trauma Surgery TI - Immunohistochemical characterization of the perivascular infiltrate in tissues adjacent to stainless steel implants compared with titanium implants UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035079773&doi=10.1007%2fs004020000230&partnerID=40&md5=1840f9417547891a838f614e062d7e0b VL - 121 ID - 1671 ER - TY - JOUR AB - Many radiologists are not familiar with the names of various instruments, surgical sponges, and needles that may be seen on intraoperative and postoperative radiographs. These devices may be intentionally placed for localization or therapeutic intervention, discovered on radiographs obtained to evaluate incorrect sponge or needle counts, or incidentally encountered on postoperative radiographs. These paraphernalia are usually described in vague nonspecific terms in radiology reports. In this article, photographs and radiographs of several instruments commonly used for intraoperative localization or therapy are presented, as well as examples of sponges, needles, and other devices that should not be found on postoperative radiographs. Familiarity with their appearances will allow a more precise and knowledgeable description in radiology reports. AD - Departments of Radiological Sciences, University of California Los Angeles (UCLA) School of Medicine, 200 UCLA Medical Plaza, Suite 165-57, Los Angeles, CA 90095-6952, USA. kwolson@bellsouth.net AN - 11112821 AU - Wolfson, K. A. AU - Seeger, L. L. AU - Kadell, B. M. AU - Eckardt, J. J. DA - Nov-Dec DO - 10.1148/radiographics.20.6.g00nv061665 DP - NLM ET - 2000/12/12 IS - 6 KW - Foreign Bodies/*diagnostic imaging Humans Intraoperative Care Postoperative Care Radiography *Surgical Instruments LA - eng N1 - Wolfson, K A Seeger, L L Kadell, B M Eckardt, J J Journal Article United States Radiographics. 2000 Nov-Dec;20(6):1665-73. doi: 10.1148/radiographics.20.6.g00nv061665. PY - 2000 SN - 0271-5333 (Print) 0271-5333 SP - 1665-73 ST - Imaging of surgical paraphernalia: what belongs in the patient and what does not T2 - Radiographics TI - Imaging of surgical paraphernalia: what belongs in the patient and what does not VL - 20 ID - 34 ER - TY - JOUR AB - Purpose or Case Report: To become familiar with the radiographic appearance of the most common surgical materials intended for use during surgical procedures in children and identify the frequency of queries for missing or incorrect count of surgical materials in clinical practice. Methods & Materials: We performed in-vitro X-rays of surgical materials, including needles, sutures, sponges, cotton balls, and compresses, intended for use during pediatric surgical procedures. Additionally, during an 8-year-period (2005-2013) we retrospectively reviewed medical records of children who underwent surgery and intra- or post-operative imaging examinations for suspected retained surgical material(s). Results: Thirty-eight queries for suspected retained surgical materials were identified in 20 male and 18 female patients, mean age 7.6 years (range:5 days-24.5 years), who underwent abdominal (n=18), cardiothoracic (n=13), brain (n=1), head and neck (n=3), upper extremity (n=1), or complex (n=2) surgical procedures. Queries were for missing needle (n=29) or needle tip (n=2), missing sponge (n=4), missing forceps (n=1), and indeterminate incorrect count (n=2). In all cases portable x-rays were performed in the operating room and findings were correlated with in vitro obtained X-rays. Thirty-eight cases were negative for retained material, and in seven cases accurate localization of the material was provided to the surgical team, while the patient was still in the operating room. Conclusions: Awareness of the radiographic appearance of surgical materials commonly used in pediatric surgery, allows for correct diagnosis and appropriate management before the patient leaves the operating room, preventing potential complications. The providing history of incorrect count or missing of surgical materials increases radiologists' diagnostic suspicion. AD - A. Ntoulia, Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, United States AU - Ntoulia, A. AU - Kerwood, J. AU - Mahboubi, S. DB - Embase DO - 10.1007/s00247-015-3297-9 KW - nitrogen 13 human radiologist radiology society patient imaging needle surgical technique operating room X ray in vitro study child diagnosis pediatric surgery forceps neck clinical practice male examination surgery medical record brain arm cotton plant leaf suture case report female LA - English M3 - Conference Abstract N1 - L71871392 2015-05-13 PY - 2015 SN - 0301-0449 SP - S214 ST - Imaging findings of suspected retained surgical materials in postoperative pediatric patients; How can the radiologist become aware? T2 - Pediatric Radiology TI - Imaging findings of suspected retained surgical materials in postoperative pediatric patients; How can the radiologist become aware? UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71871392&from=export http://dx.doi.org/10.1007/s00247-015-3297-9 VL - 45 ID - 433 ER - TY - JOUR AB - In the presented case, the radiologic, endoscopic and surgical findings of a gossypiboma that migrated into the stomach are presented. A 63-year-old woman presented with epigastric pain, and her clinical and laboratory findings were compatible with pancreatitis. Upper gastrointestinal endoscopy revealed a foreign body at the greater curvature of the stomach. Computed tomography and magnetic resonance imaging showed a mass consistent with a gossypiboma that had migrated into the stomach transmurally. This is a first case of a gossypiboma diagnosed endoscopically. AD - Başkent University, Faculty of Medicine, Department of Radiology, Adana, Turkey Department of General Surgery, Başkent University, School of Medicine, Adana, Turkey Department of Internal Medicine, Başkent University, School of Medicine, Adana, Turkey AU - Erbay, G. AU - Koç, Z. AU - Çalişkan, K. AU - Araz, F. AU - Ulusan, Ş DB - Scopus DO - 10.4318/tjg.2012.0309 IS - 1 KW - Computed tomography Magnetic resonance imaging Transmural migration of gossypiboma M3 - Article N1 - Cited By :14 Export Date: 10 November 2020 PY - 2012 SP - 54-57 ST - Imaging and clinical findings of a gossypiboma migrated into the stomach T2 - Turkish Journal of Gastroenterology TI - Imaging and clinical findings of a gossypiboma migrated into the stomach UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84859588304&doi=10.4318%2ftjg.2012.0309&partnerID=40&md5=335e24d45ef6178a264aa1614fc7b485 VL - 23 ID - 1378 ER - TY - JOUR AB - We present a case of a woman who was diagnosed with a hepatic abscess secondary to a migrated fish bone. As the patient did not improve after percutaneous drainage of the abscess, image-guided percutaneous transhepatic removal of the fish bone was performed. Fish bones in hepatic abscesses are typically removed surgically, with the fish bone left in situ in a number of cases. There has been only another reported case of percutaneous transhepatic fish bone removal. We conclude that in the rare case of a hepatic abscess complicating fish bone migration, image-guided percutaneous transhepatic removal of the offending foreign body is a feasible alternative to surgery, especially in high surgical risk patients. © 2017, EduRad. All rights reserved. AD - Radiology Department, Singapore General Hospital, Singapore Radiology Department, Changi General Hospital, Singapore AU - Lau, C. W. AU - Wong, K. M. AU - Gogna, A. DB - Scopus DO - 10.3941/jrcr.v11i2.2997 IS - 2 KW - Fish bone Foreign body migration Hepatic abscess Intervention Percutaneous removal M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2017 SP - 1-7 ST - Image-guided percutaneous transhepatic removal of fish bone from liver abscess T2 - Journal of Radiology Case Reports TI - Image-guided percutaneous transhepatic removal of fish bone from liver abscess UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85014901748&doi=10.3941%2fjrcr.v11i2.2997&partnerID=40&md5=7a8f62d3cbf43bb37ac230da41c65ed8 VL - 11 ID - 1147 ER - TY - JOUR AB - The aim of this study is to evaluate the target coverage, procedural techniques, and merits of Hybrid Interactive Mick (HIM) I125 transperineal permanent implantation (TPPI) of the prostate performed with 10 urologists in a community hospital. Detailed day 0 post-implant dosimetric evaluations of TPPI procedures were performed on 333 consecutive monotherapy patients treated between September 2000 and November 2003 at a single institution. All patients underwent TPPI with HIM. Pelvic and CXR films were obtained for a manual seed count at day 0 and again > day 90 on 175 patients. The HIM-prostate brachytherapy performed in a community hospital provided median D90, V100, and V150 values of 157Gy, 94%, and 42.3%, respectively. 18% of patients had seed migration to the lungs while 2% had seed migration to the bladder. Only 7 patients (4%) had 2 or more seeds migrate to the lungs. Procedure times average 38 minutes and number of needles used averaged 18. The post-implant urinary retention rate was 2.1% Use of HIM-prostate brachytherapy in the community setting with multiple urologists reproducibly maintained excellent and consistent dosimetric coverage. Procedure times and number of needles used were minimized, and with careful attention to image-guided technique, seed migration to bladder and lung was also minimized. AD - Department of Radiation Oncology, Memorial Regional Cancer Center, 701 North First St., Springfield, IL 62781-0001, United States Department of Urology, Memorial Regional Cancer Center, 701 North First St., Springfield, IL 62781-0001, United States AU - Shanahan, T. G. AU - Mueller, P. W. AU - Roszhart, D. A. AU - Severino, W. C. AU - Bhate, A. D. AU - Nanavati, P. J. AU - Madison, J. B. AU - Dixon, E. J. AU - Ost, L. B. AU - Strode, L. L. AU - Wands, N. S. AU - Maxey, R. B. DB - Scopus DO - 10.1177/153303460400300214 IS - 2 KW - Brachytherapy Dose evaluation Hybrid interactive brachytherapy Prostate cancer Seed migration M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2004 SP - 209-215 ST - Image Guided I125 Prostate Brachytherapy with Hybrid Interactive Mick Technique in the Community Setting: How Does it Compare? T2 - Technology in Cancer Research and Treatment TI - Image Guided I125 Prostate Brachytherapy with Hybrid Interactive Mick Technique in the Community Setting: How Does it Compare? UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-7044272491&doi=10.1177%2f153303460400300214&partnerID=40&md5=7142c6065dfc0103ee78ae7957d3e04e VL - 3 ID - 1637 ER - TY - JOUR AB - Background and objectives Intra-vesical foreign bodies are rare; it may be a result of iatrogenic injury, sexual abuse, self-insertion or following assault. Their presentation may be late and wide varieties of foreign bodies have been reported. Materials and methods A 30 year old female presented with complaints of dysuria, incontinence and hematuria for 3 years. She gives a history of C-section 3 years back following which she developed these symptoms. She was evaluated and found to have large vesical calculus. Results Patient underwent cystoscopy proceed open cystolithotomy, on retrieval the stone was found to be a calcified surgical sponge; postoperative period was uneventful. She improved symptomatically and she is kept on regular follow-up. Conclusion We report this case for its rarity and would stress on careful gauze/instrument count during any open surgical procedure. AD - D. David, Jeyasekharan Medical Trust, Nagercoil, India AU - David, D. AU - Jeyasekharan, D. DB - Embase DO - 10.1111/iju.14063 KW - adult bladder stone case report clinical article conference abstract cystoscopy dysuria female follow up foreign body hematuria human iatrogenic disease illusion incontinence information retrieval postoperative period stress surgical sponge surgical technique LA - English M3 - Conference Abstract N1 - L629086700 2019-09-02 PY - 2019 SN - 1442-2042 SP - 220 ST - An illusion of vesical calculus T2 - International Journal of Urology TI - An illusion of vesical calculus UR - https://www.embase.com/search/results?subaction=viewrecord&id=L629086700&from=export http://dx.doi.org/10.1111/iju.14063 VL - 26 ID - 310 ER - TY - JOUR AB - This is a case report of a 67 year old female patient who incidentally ingested a chicken bone, and presented to the emergency room with acute abdomen that required exploratory laparotomy later on. AD - General Surgery Department, Jordan University Hospital, Amman, Jordan AU - Albsoul, M. N. AU - Al-Ardah, M. DB - Scopus IS - 4 M3 - Article N1 - Export Date: 10 November 2020 PY - 2008 SP - 175-177 ST - Ileal perforation caused by swallowed foreign body, case presentation and review of literature T2 - Journal of the Bahrain Medical Society TI - Ileal perforation caused by swallowed foreign body, case presentation and review of literature UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-62649085660&partnerID=40&md5=1273921ad5308c374b3ef9880b46624c VL - 20 ID - 1514 ER - TY - JOUR AB - IgG4-related disease has evolved from originally being recognized as a form of pancreatitis to encompass diseases of numerous organs including the hypophysis and one reported case of dural involvement. A search of the University of Virginia, Division of Neuropathology files for 10 years identified ten cases of unexplained lymphoplasmacytic meningeal inflammation that we then evaluated using immunohistochemical stains for IgG4 and IgG. Ten control cases including sarcoidosis (4), tuberculosis (1), bacterial abscess (2), Langerhans cell histiocytosis (2), and foreign body reaction (1) were also examined. The number of IgG4-positive plasma cells was counted in five high power fields (HPFs) and an average per HPF was calculated. Cases that contained greater than ten IgG4-positive cells/HPF were considered to be IgG4- related. Five of the study cases met these criteria, including one case of leptomeningeal inflammation. All cases exhibited the typical histological features of IgG4-related disease including lymphoplasmacytic inflammation, fibrosis, and phlebitis. The dural-based lesions appear to represent a subset of the cases historically diagnosed as idiopathic hypertrophic pachymeningitis. While the leptomeningeal process most closely resembles non-vasculitic autoimmune inflammatory meningoencephalitis. Given these findings, IgG4-related meningitis should be considered in the differential diagnosis of meningeal inflammatory lesions after stringent clinical and histologic criteria are used to rule out other possible diagnoses. © Springer-Verlag 2010. AD - M. B. S. Lopes, Division of Neuropathology, Department of Pathology, University of Virginia School of Medicine, 1215 Lee St., Charlottesville, VA 22908-0214, United States AU - Lindstrom, K. M. AU - Cousar, J. B. AU - Lopes, M. B. S. DB - Embase Medline DO - 10.1007/s00401-010-0746-2 IS - 6 KW - immunoglobulin G immunoglobulin G4 steroid adult aged article brain surgery cell count clinical article clinical feature controlled study diagnostic test accuracy study differential diagnosis dura mater female fibrosis follow up histopathology human human tissue immunohistochemistry immunoreactivity leptomeninx male meningitis meningoencephalitis meninx disorder phlebitis plasma cell priority journal treatment response LA - English M3 - Article N1 - L51072408 2010-09-21 2011-01-26 PY - 2010 SN - 0001-6322 SP - 765-776 ST - IgG4-related meningeal disease: Clinico-pathological features and proposal for diagnostic criteria T2 - Acta Neuropathologica TI - IgG4-related meningeal disease: Clinico-pathological features and proposal for diagnostic criteria UR - https://www.embase.com/search/results?subaction=viewrecord&id=L51072408&from=export http://dx.doi.org/10.1007/s00401-010-0746-2 VL - 120 ID - 550 ER - TY - JOUR AU - Arellanes-GarcÍa, L. AU - Navarro-López, P. AU - Río, L. E. C. D. AU - Unzueta-Medina, J. A. DB - Scopus DO - 10.1097/IIO.0b013e31817d84af IS - 3 M3 - Review N1 - Cited By :13 Export Date: 10 November 2020 PY - 2008 SP - 61-74 ST - Idiopathic intermediate uveitis in childhood T2 - International Ophthalmology Clinics TI - Idiopathic intermediate uveitis in childhood UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-51649114109&doi=10.1097%2fIIO.0b013e31817d84af&partnerID=40&md5=90ce38b79280fe1c0d58f38cae6027c6 VL - 48 ID - 1528 ER - TY - JOUR AB - Isolated granulomatous inflammation of the appendix is extremely rare, and its etiology is still unknown. Thus, differentiating between idiopathic granulomatous appendicitis and isolated appendiceal Crohn's disease is difficult. We report a case of idiopathic granulomatous appendicitis with long-term follow-up after surgery. A 26-year-old woman was referred to our hospital for investigation of persistent right lower abdominal pain. Abdominal computed tomography showed a mass, suggesting an inflammatory tumor around the appendix; thus, we suspected subacute appendicitis and performed laparoscopically assisted ileocecal resection. Histological examination of the resected specimen revealed several noncaseous epithelioid granulomas in the wall of the appendix, but no foreign bodies, obstructing lesions, or parasites. Stains for acid-fast bacillus and fungi, and serology for yersinia were all negative. The patient has been followed up for 9 years and remains asymptomatic. This clinical course suggests that her isolated granulomatous appendicitis was idiopathic granulomatous appendicitis unrelated to Crohn's disease. © 2007 Springer-Verlag. AD - Department of Surgery, Rinku General Medical Center, Izumisano Municipal Hospital, Izumisano, Osaka 598-0048, Japan Department of Pathology, Rinku General Medical Center, Izumisano Municipal Hospital, 2-23 Rinku Ohrai Kita, Izumisano, Osaka 598-0048, Japan AU - Mizushima, T. AU - Ito, T. AU - Mizuno, H. AU - Udatsu, Y. AU - Miyazaki, Y. AU - Imakita, M. AU - Iwase, K. DB - Scopus DO - 10.1007/s00595-006-3475-3 IS - 8 KW - Crohn's disease Idiopathic granulomatous appendicitis Long-term follow-up M3 - Article N1 - Cited By :11 Export Date: 10 November 2020 PY - 2007 SP - 690-693 ST - Idiopathic granulomatous appendicitis treated surgically with long-term follow-up: Report of a case T2 - Surgery Today TI - Idiopathic granulomatous appendicitis treated surgically with long-term follow-up: Report of a case UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-34547124812&doi=10.1007%2fs00595-006-3475-3&partnerID=40&md5=bb88ad940aaa23fd9f73a90d79316555 VL - 37 ID - 1559 ER - TY - JOUR AB - Many surgical procedures involve the use of very small surgical needles. In the event that a postoperative needle count is incorrect, traditionally an x-ray has been taken to find the needle. Little data exist to recommend the smallest surgical needle that can be identified with conventional radiographic techniques and the optimum technique for finding lost surgical needles. In this quality assurance project x-rays of various size surgical needles were taken. The smallest seen by the majority of observers was 17 mm. The radiographic technique of choice for optimum detection of lost surgical needles was imaging with a mobile image intensifier. AD - Cabrini Hospital, Malvern, Victoria, Australia. AN - 12885068 AU - Macilquham, M. D. AU - Riley, R. G. AU - Grossberg, P. DA - Jul DO - 10.1016/s0001-2092(06)61347-1 DP - NLM ET - 2003/07/30 IS - 1 KW - Abdomen Australia Foreign Bodies/*diagnostic imaging Humans *Needles Phantoms, Imaging Radiographic Image Enhancement Radiography, Thoracic/*methods Random Allocation *Surgical Instruments *Thorax LA - eng N1 - Macilquham, Michael D Riley, Robin G Grossberg, Peter Comparative Study Journal Article United States AORN J. 2003 Jul;78(1):73-8. doi: 10.1016/s0001-2092(06)61347-1. PY - 2003 SN - 0001-2092 (Print) 0001-2092 SP - 73-8 ST - Identifying lost surgical needles using radiographic techniques T2 - Aorn j TI - Identifying lost surgical needles using radiographic techniques VL - 78 ID - 42 ER - TY - JOUR AB - Fournier's gangrene (FG) is an infrequent but highly lethal infection. Here we report a 74-year-old man who presented with genital swelling and severe malaise. Based on the physical and imaging examination results, the diagnosis of FG was confirmed. Intraoperative findings showed dirty necrosis of soft tissue, and a splinter-shaped foreign body was found in the perirectal region. The foreign body was thought to be the cause of the condition, and it was analyzed using Fourier transform infrared spectroscopy. We found that the foreign body was a mixture of calcium phosphate and protein, suggesting that the splinter was a bone. Moreover, during the medical interview, the patient mentioned about intake of fish around the time of onset of symptoms. Therefore, to confirm the results of the analysis, DNA was extracted from the foreign body, and genomic PCR with subsequent sequence analysis was performed. The DNA sequence was identical to that of Oncorhynchus kisutch, a salmon that is a very popular food in Japan. On the basis of these findings, we concluded that FG in this case was caused by the penetration into the rectum of an accidentally ingested fish bone. Although some cases of intra-abdominal abscess due to accidental ingestion of fish bone have been reported, FG caused by fish bone is extremely rare. © 2014 Japanese Dermatological Association. AD - Department of Dermatology, Faculty of Medicine, University of Yamanashi, 1110 Shimogato, Chuo, Yamanashi 409-3898, Japan Department of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi Chuo, Japan AU - Shimizu, T. AU - Harada, K. AU - Akazawa, S. AU - Yamaguchi, M. AU - Inozume, T. AU - Kawamura, T. AU - Shibagaki, N. AU - Momosawa, A. AU - Shimada, S. DB - Scopus DO - 10.1111/1346-8138.12514 IS - 6 KW - bacterial infection fish bone foreign body Fourier transform infrared spectroscopy Fournier's gangrene M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2014 SP - 547-550 ST - Identification of the cause of severe skin infection by Fournier transform infrared spectroscopy: A case of Fournier's gangrene caused by fish bone T2 - Journal of Dermatology TI - Identification of the cause of severe skin infection by Fournier transform infrared spectroscopy: A case of Fournier's gangrene caused by fish bone UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84902131329&doi=10.1111%2f1346-8138.12514&partnerID=40&md5=2f88cca98660853cbc1516160999d0fe VL - 41 ID - 1277 ER - TY - JOUR AD - Assistant Professor and Administrative Clinical Coordinator in the PA Program, Pacific University, Hillsboro, Oregon AN - 104990107. Language: English. Entry Date: 20110128. Revision Date: 20200708. Publication Type: Journal Article AU - Cobb, Torry G. DB - ccm DO - 10.1097/01720610-201012000-00008 DP - EBSCOhost IS - 12 KW - Retained Instruments -- Prevention and Control Retained Instruments -- Risk Factors Bar Coding Liability, Legal Retained Instruments -- Complications Retained Instruments -- Economics Surgical Count Procedure X-Rays N1 - diagnostic images; tables/charts. Journal Subset: Allied Health; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Patient Safety; Perioperative Care. NLM UID: 9513102. PMID: NLM21229835. PY - 2010 SN - 1547-1896 SP - 33-40 ST - Iatrogenic retention of surgical objects: risk factors and prevention strategies T2 - JAAPA: Journal of the American Academy of Physician Assistants (Haymarket Media, Inc.) TI - Iatrogenic retention of surgical objects: risk factors and prevention strategies UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104990107&site=ehost-live&scope=site VL - 23 ID - 766 ER - TY - JOUR AB - Adhesion of microorganisms to biomaterials with subsequent formation of biofilms on such foreign bodies as orthopedic trauma hardware is a critical factor in implant-associated infections; once a biofilm has been established, its microorganisms become recalcitrant to the host's immune surveillance and markedly resistant to drugs. We have previously reported that painting with the hydrophobic polycation N,N-dodecyl,methyl-PEI (PEI = polyethylenimine) renders solid surfaces bactericidal in vitro. Herein we observe that N,N-dodecyl,methyl-PEI-derivatized titanium and stainless steel surfaces resist biofilm formation by Staphylococcus aureus compared to the untreated ones. Using imaging, microbiology-, histopathology-, and scanning electron microscopy (SEM) experiments in a clinically relevant large-animal (sheep) trauma model, we subsequently demonstrate in vivo that orthopedic fracture hardware painted with N,N-dodecyl,methyl-PEI not only prevents implant colonization with biofilm but also promotes bone healing. Functionalizing orthopedic hardware with hydrophobic polycations thus holds promise in supporting bone healing in the presence of infection in veterinary and human orthopedic patients. © 2011 Elsevier Ltd. AD - Comparative Orthopaedic Research Laboratory, Department of Clinical Studies, New Bolton Center, University of Pennsylvania School of Veterinary Medicine, Kennett Square, PA 19348, United States Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, United States Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States AU - Schaer, T. P. AU - Stewart, S. AU - Hsu, B. B. AU - Klibanov, A. M. DB - Scopus DO - 10.1016/j.biomaterials.2011.10.038 IS - 5 KW - Animal model Bactericidal Hardware Infection Orthopedics M3 - Article N1 - Cited By :94 Export Date: 10 November 2020 PY - 2012 SP - 1245-1254 ST - Hydrophobic polycationic coatings that inhibit biofilms and support bone healing during infection T2 - Biomaterials TI - Hydrophobic polycationic coatings that inhibit biofilms and support bone healing during infection UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-83355173915&doi=10.1016%2fj.biomaterials.2011.10.038&partnerID=40&md5=21d322a19b64dec75c5b6b0e5e7cb452 VL - 33 ID - 1386 ER - TY - JOUR AB - To investigate the effects of polymer chemistry and topology (linear or graft copolymer) on in vivo biocompatibility and biostability based on cage implant system, various hydrogels, composed of short hydrophilic [polyethylene oxide (PEO)] and hydrophobic block, were prepared by polycondensation reaction. Poly(tetramethylene oxide) (PTMO) or poly(dimethyl siloxane) (PDMS) was chosen as a hydrophobic block because of their wide utilization as a biomaterial. By using the specimens retrieved from rats killed after 1, 2, 3, 5, and 7 weeks' implantation, cellular and material responses were assessed. Most hydrogels showed a comparable value of macrophage density to Pellethane®, control polymer, whereas they did significantly lower foreign body giant cell (FBGC) density and coverage because of the presence of PEO. However, PEO block length and polymer topology did not affect macrophage adhesion and FBGC formation in our polymer composition. The hydrogel based on PDMS alone showed significantly lower macrophage density and FBGC density than Pellethane®, indicating that PDMS plays a role in inhibiting cellular adhesion. The results obtained from gel permeation chromatography curve and Fourier transform infrared spectra exhibited that all the polymers were susceptible to oxidative degradation in vivo. Although Pellethane® revealed surface degradation by 5 weeks in vivo, hydrogels showed rapid degradation in the bulk within 2 weeks because of the penetration of oxidative chemicals released from phagocytic cells into PEO domain of phase-separated hydrogels. The more significant degradation was observed in the hydrogels with longer PEO block and PTMO as a hydrophobic block instead of PDMS. It was evident that the minor degradation could be achieved by grafting PEO and adopting PDMS as a hydrophobic block in the hydrogel. © 2002 Wiley Periodicals, Inc. AD - Ctr. for Biomaterials and Biotech., Dept. of Mat. Sci. and Engineering, Kwangju Inst. of Sci. and Technology, 1 Oryong-dong, Puk-gu, Kwangju 500-712, South Korea AU - Park, J. H. AU - Bae, Y. H. DB - Scopus DO - 10.1002/jbm.a.10424 IS - 2 KW - Biocompatibility Biostability Hydrogel Poly(dimethyl siloxane) Poly(ethylene oxide) Poly(tetramethylene oxide) M3 - Article N1 - Cited By :29 Export Date: 10 November 2020 PY - 2003 SP - 309-319 ST - Hydrogels based on poly(ethylene oxide) and poly(tetramethylene oxide) or poly(dimethyl siloxane). III. In vivo biocompatibility and biostability T2 - Journal of Biomedical Materials Research - Part A TI - Hydrogels based on poly(ethylene oxide) and poly(tetramethylene oxide) or poly(dimethyl siloxane). III. In vivo biocompatibility and biostability UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0041922643&doi=10.1002%2fjbm.a.10424&partnerID=40&md5=2dd773cbc9182257b8b8495c9b3e6a84 VL - 64 ID - 1645 ER - TY - JOUR AD - Facility Administrator, Northeast Baptist Surgery Center and St Luke's Baptist Surgery Center, San Antonio, TX AN - 107066114. Language: English. Entry Date: 20011109. Revision Date: 20150818. Publication Type: Journal Article AU - McEwen, D. R. DB - ccm DP - EBSCOhost IS - 5 KW - Surgical Count Procedure -- Education Risk Management Perioperative Nursing Staff Development Foreign Bodies Teaching Methods Teaching Materials Risk Factors Texas N1 - pictorial. Journal Subset: Nursing; Peer Reviewed; USA. NLM UID: 101091115. PY - 2001 SP - 57-58 ST - Human resources. A creative approach to risk management T2 - SSM TI - Human resources. A creative approach to risk management UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107066114&site=ehost-live&scope=site VL - 7 ID - 918 ER - TY - JOUR AB - A case study is presented, based on the experience of the US Veterans Affairs health system, which shows the benefits of healthcare personnel understanding human factors engineering (HFE) and how it relates to patient safety. After HFE training, personnel are better able to use a systems-oriented approach during adverse event analysis. Without some appreciation of HFE, the focus of adverse event analyses (e.g. root cause analysis (RCA)) is often misguided towards policies or an individual's shortcomings, leading to ineffective solutions. The case study followed the investigation by an RCA team of a retained sponge following cardiac surgery. The team began with a focus on the specific failings of the surgical nurse and outdated policies. HFE design demonstrations were used to redirect the team's focus to more systems-oriented issues, which could be uncovered even when events appeared to be related to policy or training, and to point them towards examining the design of systems that contributed to the event. The team was thus able to identify design flaws and make improvements to the design of the forms and computer systems that were key to preventing such events from recurring. AD - National Center for Patient Safety, Department of Veterans Affairs, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 48106; john.gosbee@med.va.gov AN - 106878911. Language: English. Entry Date: 20031024. Revision Date: 20200708. Publication Type: Journal Article AU - Gosbee, J. AU - Anderson, T. DB - ccm DO - 10.1136/qhc.12.2.119 DP - EBSCOhost IS - 2 KW - Coronary Artery Bypass -- Adverse Effects Ergonomics Foreign Bodies Patient Safety Root Cause Analysis Surgical Count Procedure Treatment Errors -- Prevention and Control Hospitals, Veterans Organizational Policies Process Assessment (Health Care) Surgical Sponges Systems Analysis United States United States Department of Veterans Affairs N1 - case study. Journal Subset: Blind Peer Reviewed; Europe; Expert Peer Reviewed; Health Services Administration; Peer Reviewed; UK & Ireland. NLM UID: 101136980. PMID: NLM12679508. PY - 2003 SN - 1475-3898 SP - 119-121 ST - Human factors engineering design demonstrations can enlighten your RCA team T2 - Quality & Safety in Health Care TI - Human factors engineering design demonstrations can enlighten your RCA team UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106878911&site=ehost-live&scope=site VL - 12 ID - 880 ER - TY - JOUR AB - Introduction Most patients with foreign bodies in their rectums present to medical institutions within a few days. In this report, we describe a foreign body in the rectum in situ for 5 months that resulted in a huge rectovesical fistula 4 cm in diameter, requiring emergency laparotomy. Presentation of case A 59-year-old man, who had undergone rectal foreign body extraction via the anal canal without any complications 7 years previously, presented with abdominal pain and diarrhea. Computed tomography revealed a cup-shaped rectal foreign body and huge rectovesical fistula. We performed an emergency laparotomy. There was no contaminated ascites. The adhesion around the fistula was too stiff to be dissected. We incised the rectal wall, excised the ceramic cup-shaped foreign body, and detected a fistula approximately 4 cm in diameter. We performed sigmoid colostomy, and the incised rectal wall and the bladder wall were sutured, and the residual rectum was supposed to function as a part of the bladder. After the surgery, no severe complications occurred. The patient told us that he inserted the foreign body himself 5 months earlier, and urine had appeared in the stool in the previous month. Discussion A long-term retained rectal foreign body is very rare and could create an abnormal huge fistula between the pelvic organs because of prolonged pressure on the walls of the pelvic organs. Conclusion In patients with a long-term retained rectal foreign body, we should prepare for surgical treatment of not only the rectum but also the other pelvic organs. © 2017 The Author(s) AD - Gastroenterological Surgery, Kameda Medical Center, Higashimachi 929, Kamogawa, Chiba 296-8602, Japan AU - Kiyasu, Y. AU - Kano, N. DB - Scopus DO - 10.1016/j.ijscr.2017.01.039 KW - Large rectovesical fistula Pelvic surgery Rectal foreign body Sigmoid colostomy M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2017 SP - 163-166 ST - Huge rectovesical fistula due to long-term retention of a rectal foreign body: A case report and review of the literature T2 - International Journal of Surgery Case Reports TI - Huge rectovesical fistula due to long-term retention of a rectal foreign body: A case report and review of the literature UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011024647&doi=10.1016%2fj.ijscr.2017.01.039&partnerID=40&md5=712cfba91a6fe7d25494066ad4ae9519 VL - 31 ID - 1153 ER - TY - JOUR AN - 105425537. Language: English. Entry Date: 20091002. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 9 KW - Needles Retained Instruments -- Prevention and Control Surgical Count Procedure N1 - brief item. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2009 SN - 0190-5066 SP - 92-92 ST - How to avoid retained needles T2 - Same-Day Surgery TI - How to avoid retained needles UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105425537&site=ehost-live&scope=site VL - 33 ID - 929 ER - TY - JOUR AD - Nursing Education Specialist, Mayo Clinic, Rochester, Minn.; ORnurse@wolterskluwer.com AN - 108206969. Language: English. Entry Date: 20120106. Revision Date: 20200706. Publication Type: Journal Article AU - Thompson, Elizabeth M. DB - ccm DO - 10.1097/01.orn.0000406639.26801.75 DP - EBSCOhost IS - 6 KW - Patient Safety Perioperative Nursing Retained Instruments -- Prevention and Control Surgical Count Procedure Teamwork Audit Leadership Nursing Management Staff Development N1 - editorial. Journal Subset: Double Blind Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 101308226. PY - 2011 SN - 1933-3145 SP - 5-5 ST - How teamwork can boost patient safety T2 - OR Nurse TI - How teamwork can boost patient safety UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108206969&site=ehost-live&scope=site VL - 5 ID - 912 ER - TY - JOUR AB - BACKGROUND: Intraoperative instrument recounts are performed to avoid retained foreign surgical items. These additional counts, however, beget risks of their own, including prolonged operative times, exposure to radiation, and increased cost. Our study aimed to identify factors that increase the likelihood of instrument recounts during plastic surgery procedures, and use our findings to guide potential solutions for preventing unnecessary recounts across all surgical fields. STUDY DESIGN: This is a retrospective review of all plastic surgical cases in the main operating setting at New York University Langone Medical Center (NYULMC) between March 2014 and February 2015. RESULTS: Of 1285 plastic surgery cases, 35 (2.7%) reported a missing instrument necessitating a recount. Of all subspecialties within plastic surgery, only microsurgery conferred an increased risk of a recount event. We identified multiple factors that increased the odds of a recount event, including increased operative time, number of surgical sites, and intraoperative instrument handoffs. CONCLUSION: Instrument recounts, although designed to prevent inadvertently retained surgical items, present inherent risks of their own. In a large retrospective review of plastic surgery cases at our medical center, we identified many factors that increased the likelihood of an instrument recount. On the basis of our findings and prior literature, we recommend limiting the number of staff handling instrument, the number of handoffs, and a heightened awareness by surgeons and perioperative staff of specific procedures and factors that increase the risk of a miscount event. AD - Hansjörg Wyss Department of Plastic Surgery, New York University Langone Medical Center, New York, NY, USA. Hansjörg Wyss Department of Plastic Surgery, New York University Langone Medical Center, New York, NY, USA. Electronic address: Daniel.Ceradini@nyumc.org. AN - 28734751 AU - Reformat, D. D. AU - David, J. A. AU - Diaz-Siso, J. R. AU - Plana, N. M. AU - Wang, A. AU - Brownstone, N. D. AU - Ceradini, D. J. DA - Sep DO - 10.1016/j.bjps.2017.06.028 DP - NLM ET - 2017/07/25 IS - 9 KW - Adult Humans Middle Aged Operating Rooms/*statistics & numerical data *Reconstructive Surgical Procedures/instrumentation Retrospective Studies Surgical Instruments/*statistics & numerical data Miscount Patient safety Recount Retained surgical items Risk factors Surgical instruments LA - eng N1 - 1878-0539 Reformat, Derek D David, Joshua A Diaz-Siso, J Rodrigo Plana, Natalie M Wang, Annie Brownstone, Nicholas D Ceradini, Daniel J Journal Article Netherlands J Plast Reconstr Aesthet Surg. 2017 Sep;70(9):1285-1291. doi: 10.1016/j.bjps.2017.06.028. Epub 2017 Jun 28. PY - 2017 SN - 1748-6815 SP - 1285-1291 ST - How many people work in your operating room? An assessment of factors associated with instrument recounts within plastic surgery T2 - J Plast Reconstr Aesthet Surg TI - How many people work in your operating room? An assessment of factors associated with instrument recounts within plastic surgery VL - 70 ID - 196 ER - TY - JOUR AN - 108490032. Language: English. Entry Date: 20150817. Revision Date: 20161213. Publication Type: Article. Note: For CE see Supplement page 84. Journal Subset: Biomedical DB - ccm DP - EBSCOhost IS - 8 KW - Adverse Health Care Event -- Risk Factors Behavior -- Evaluation Coding Human Error -- Classification Retained Instruments Wrong Site Surgery World Wide Web Information Resources Professional Compliance Organizational Culture Education, Continuing (Credit) N1 - Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2015 SN - 0190-5066 SP - 78-79 ST - How does human behavior lead to surgical errors? Mayo Clinic researchers count the ways T2 - Same-Day Surgery TI - How does human behavior lead to surgical errors? Mayo Clinic researchers count the ways UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108490032&site=ehost-live&scope=site VL - 39 ID - 791 ER - TY - JOUR AB - Objective: To compare the tissue reaction produced by 2 gauges of implanted polyglactin 910(Vicryl) suture material in human skin. Methods: A prospective, double masked, parallel randomized IRB approved clinical trial. Consecutive patients with involutional entropion and horizontal eyelid laxity were randomly allocated to 5/0 or 7/0 gauge test suture groups. Symptoms were alleviated during the wait for definitive surgery by placement of eyelid everting sutures. After 28 days, surgical entropion correction including eyelid wedge excision was achieved. Histological analysis was carried out, masked to the suture gauge used, on the excised eyelid containing one of the temporary everting sutures. Both patient and analyst were masked to the suture group. The four primary outcome measurements were granuloma outer diameter, central cellular diameter, giant cell number and area of fibrous coat and a statistical comparison made between suture gauge groups. Results: 21 patients were allocated to each group, and histological analysis was possible in 36 patients. Significant suture-related granulomatous inflammatory reactions were found in all specimens. Medians of the measurements for 5/0 and 7/0 gauge sutures, respectively, were 0.855mm versus 0.387mm granuloma outer diameter (p=0.0001); 0.464mm versus 0.250mm central cellular element diameter (p=0.0003); 0.194mm2 versus 0.053mm2 fibrous coat area (p=0.0009) and 0.8 versus 1.2 giant cell number (p=0.7511). Conclusions: Polyglycolic acid sutures elicit a significant foreign body inflammatory response proportional to suture gauge. This reaction may be minimized by early suture removal. The study validates a novel and ethical approach to the examination of human skin response to implanted suture material. AD - Clinical Fellow in Oculoplastic Surgery, Royal Bournemouth Hospital, Castle Lane East, Bournemouth, Dorset, BH7 7DW, United Kingdom Salisbury NHS Foundation Trust, Wiltshire, United Kingdom AU - Cartmill, B. T. AU - Parham, D. M. AU - Strike, P. W. AU - Griffiths, L. AU - Parkin, B. DB - Scopus DO - 10.3109/01676830.2014.950285 IS - 6 KW - Human polyglactin response Polyglactin tissue reaction Polyglactin-induced scarring Stitch granuloma Suture granuloma M3 - Article N1 - Cited By :11 Export Date: 10 November 2020 PY - 2014 SP - 437-443 ST - How do absorbable sutures absorb? A prospective double-blind randomized clinical study of tissue reaction to polyglactin 910 sutures in human skin T2 - Orbit TI - How do absorbable sutures absorb? A prospective double-blind randomized clinical study of tissue reaction to polyglactin 910 sutures in human skin UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84908647989&doi=10.3109%2f01676830.2014.950285&partnerID=40&md5=1406420d929fedc45df288b67e80c302 VL - 33 ID - 1288 ER - TY - JOUR AB - Objectives: To describe acute and sub acute aspects of histological and immunohistochemical response to PP implant in a rat subcutaneous model based on objective methods. Materials and Methods: Thirty rats had a PP mesh subcutaneously implanted and the same dissection on the other side of abdomen but without mesh (sham). The animals were euthanized after 4 and 30 days. Six slides were prepared using the tissue removed: one stained with hematoxylin-eosin (inflammation assessment); one unstained (birefringence evaluation) and four slides for immunohistochemical processing: IL-1 and TNF-α (pro-inflammatory cytokines), MMP-2 (collagen metabolism) and CD-31 (angiogenesis). The area of inflammation, the birefringence index, the area of immunoreactivity and the number of vessels were objectively measured. Results: A larger area of inflammatory reaction was observed in PP compared to sham on the 4th and on the 30th day (p=0.0002). After 4 days, PP presented higher TNF (p=0.0001) immunoreactivity than sham and no differences were observed in MMP- 2 (p=0.06) and IL-1 (p=0.08). After 30 days, a reduction of IL-1 (p=0.010) and TNF (p=0.016) for PP and of IL-1 (p=0.010) for sham were observed. Moreover, area of MMP-2 immunoreactivity decreased over time for PP group (p=0.018). Birefringence index and vessel counting showed no differences between PP and sham (p=0.27 and p=0.58, respectively). Conclusions: The implantation of monofilament and macroporous polypropylene in the subcutaneous of rats resulted in increased inflammatory activity and higher TNF production in the early post implant phase. After 30 days, PP has similar cytokines immunoreactivity, vessel density and extracellular matrix organization. AD - Faculdade de Ciências Médicas, Universidade de Campinas, Campinas, Brazil Instituto de Biologia, Universidade de Campinas, Campinas, Brazil Laboratório de Investigação Patologica, Centro de Investigação em Pediatria, Campinas, Brazil AU - Prudente, A. AU - Fávaro, W. J. AU - Filho, P. L. AU - Riccetto, C. L. Z. DB - Scopus DO - 10.1590/S1677-5538.IBJU.2015.0289 IS - 3 KW - Foreign body reaction Graft versus host reaction Immunohistochemistry Pelvic organ prolapse Polypropylenes Urinary incontinence M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2016 SP - 585-593 ST - Host inflammatory response to polypropylene implants: Insights from a quantitative immunohistochemical and birefringence analysis in a rat subcutaneous model T2 - International Braz J Urol TI - Host inflammatory response to polypropylene implants: Insights from a quantitative immunohistochemical and birefringence analysis in a rat subcutaneous model UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84978128523&doi=10.1590%2fS1677-5538.IBJU.2015.0289&partnerID=40&md5=bdd03908abb09910994542e106080cd0 VL - 42 ID - 1185 ER - TY - JOUR AB - The article reports on the case of a 27 year old gastric banding patient who sued her surgeon and her hospital for leaving a sponge inside her after surgery and in which a trial court determined that both defendants were liable for the error and ordered them to pay $25,000 each in damages. AD - Partner Kaufman Borgeest & Ryan New York, NY Associate Kaufman Borgeest & Ryan New York, NY Director of Risk and Claims Management The New York Hospital Medical Center of Queens Flushing, NY AN - 76912443. Language: English. Entry Date: 20121016. Revision Date: 20190422. Publication Type: Article AU - Rubin, Jonathan D. AU - Brown, Sandra L. AU - Safran, Alvin DB - ccm DP - EBSCOhost IS - 7 KW - Retained Instruments -- Legislation and Jurisprudence -- Louisiana Liability, Legal Surgeons -- Legislation and Jurisprudence -- Louisiana Hospitals -- Legislation and Jurisprudence -- Louisiana Surgical Count Procedure Louisiana Surgical Sponges Bariatric Surgery -- Adverse Effects N1 - legal case. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. Legal Case: Louisiana Court of Appeal, Third Circuit. No. 11-0318. NLM UID: 7810150. PY - 2012 SN - 0190-5066 SP - 74-75 ST - Hospital, surgeon liable for sponge left in patient T2 - Same-Day Surgery TI - Hospital, surgeon liable for sponge left in patient UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=76912443&site=ehost-live&scope=site VL - 36 ID - 834 ER - TY - JOUR AB - Objective: Present study was performed to evaluate the histological response of rat middle ear mucosa following implantation of Apaceram® granules, a synthetic dense hydroxyapatite [Ca10(PO4)6(OH)2], prepared from commercially available synthetic auditory ossicle, and to assess the precise histological response of the rat middle ear to implantation of Apaceram® granules, by microscopic examination of mucosal tissue at various time points after implantation. Methods: Apaceram® granules were implanted in the temporal bulla of 32 rats. As control, sham surgery was performed in a group of ten rats. Bulla specimens were removed at 1, 3, 7, 14, and 30 days after surgery in the implant and control groups, and at 90, 180 and 300 days in the implant group. Specimens were decalcified, sectioned at a thickness of 6 μm, and stained with haematoxylin and eosin, and Mallory's azan for histological examination of mucosal tissue. Results: Evidence of inflammatory reaction was slightly greater in the implant group than in controls. Lymphocyte and macrophage counts were higher in the implant group 1 day after surgery, but decreased to similar levels by day 3, and continued to decrease thereafter, and few were observed in the implant group at 300 days. Neutrophils observed at 1 day after surgery were not evident in either group at 3 days. Gradual fibrosis development continued in both groups over all time points studied. Foreign body giant cells were never observed in either group. No bony reaction was observed in any specimen. Conclusion: The results of this study suggest that Apaceram® is biocompatible and suitable for reconstructive ear surgery. Copyright © 2001 Elsevier Science Ireland Ltd. AD - Department of Pathology, School of Medicine, University of Tokushima, Tokushima 770-8503, Japan Division of Clinical Otology, School of Medicine, University of Tokushima, Tokushima 770-8503, Japan Department of Otolaryngology, Okayama University Medical School, Okayama, Japan Department of Orthodontics, University of Tokushima, School of Dentistry, Tokushima, Japan Department of Orthodontics, Okayama University Dental School, Okayama, Japan AU - Ye, Q. AU - Ohsaki, K. AU - Li, K. AU - Li, D. J. AU - Zhu, C. S. AU - Ogawa, T. AU - Tenshin, S. AU - Takano-Yamamoto, T. DB - Scopus DO - 10.1016/S0385-8146(00)00079-1 IS - 2 KW - Bulla of rat Cell count Hydroxyapatite Inflammatory cell M3 - Article N1 - Cited By :21 Export Date: 10 November 2020 PY - 2001 SP - 131-136 ST - Histological reaction to hydroxyapatite in the middle ear of rats T2 - Auris Nasus Larynx TI - Histological reaction to hydroxyapatite in the middle ear of rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035116350&doi=10.1016%2fS0385-8146%2800%2900079-1&partnerID=40&md5=f0eb8b7df36e07e8281459bbd9f9c310 VL - 28 ID - 1672 ER - TY - JOUR AB - PURPOSE: We prospectively evaluated the histological inflammatory response to the large polypropylene transvaginal mesh used for pelvic organ prolapse surgery. MATERIALS AND METHODS: Ten patients and 8 controls underwent vaginal punch biopsy sampling before surgery and patients also underwent it 1 year after pelvic reconstructive surgery using polypropylene mesh. Foreign body response to the mesh was assessed using a combination of histological, semiquantitative and computerized image based analysis. RESULTS: Compared to preoperative histology there was a significant postoperative increase in macrophage and mast cell counts (p = 0.03 and 0.01) but no significant changes in the count of cells involved primarily in the infectious cell response or collagen density and the elastin area fraction at the mesh-tissue interface (p = 0.2 and 0.3, respectively). Three cases of mild granuloma formation and 2 of mild erosion were observed. There was no significant change in epithelial thickness when comparing preoperative and postoperative samples. CONCLUSIONS: When used for pelvic reconstructive surgery, macroporous monofilament polypropylene mesh induces a mild but persistent foreign body reaction. AD - Division of Surgery and Urology, Department of Clinical Sciences, Danderyd University Hospital, Stockholm, Sweden. AN - 19152931 AU - Elmer, C. AU - Blomgren, B. AU - Falconer, C. AU - Zhang, A. AU - Altman, D. DA - Mar DO - 10.1016/j.juro.2008.11.030 DP - NLM ET - 2009/01/21 IS - 3 KW - Adult Aged Female Foreign-Body Reaction/*etiology/*pathology Humans Middle Aged Polypropylenes/*adverse effects Prospective Studies Surgical Mesh/*adverse effects Uterine Prolapse/*surgery LA - eng N1 - 1527-3792 Elmer, Caroline Blomgren, Bo Falconer, Christian Zhang, Anju Altman, Daniel Journal Article Research Support, Non-U.S. Gov't United States J Urol. 2009 Mar;181(3):1189-95. doi: 10.1016/j.juro.2008.11.030. Epub 2009 Jan 18. PY - 2009 SN - 0022-5347 SP - 1189-95 ST - Histological inflammatory response to transvaginal polypropylene mesh for pelvic reconstructive surgery T2 - J Urol TI - Histological inflammatory response to transvaginal polypropylene mesh for pelvic reconstructive surgery VL - 181 ID - 86 ER - TY - JOUR AB - Objective. To evaluate changes in histology and semen variables after using an elastomeric-hydrogel matrix plug as a reversible vasectomy device in dogs, and to determine the potential applications for improving fertility after vasectomy reversal. Materials and methods. Semen samples from six adult male dogs were obtained after left vasal ligation, placement of the plug in the right vas deferens, and subsequent removal of the plug. The vasa, epididymides and testes were evaluated histologically in four of the dogs after removal of the implant. Results. No sperm were present in the ejaculate after the plug was removed. Histological sections showed intraluminal spermatids in areas where the plug had been placed. The lumen was occluded, secondary to foreign-body giant-cell reaction, at the vasotomy suture site, but other areas of the vas previously containing the implant remained patent after it was removed. Conclusions. There were no sperm in the ejaculate after the plug was removed because the vasal lumen was occluded as a result of an inflammatory reaction to the suture material. In contrast, areas that had contained the implant but without a vasotomy suture were not inflamed. We suggest that further trials comparing various suture materials are carried out to determine if patency rates can be improved during vasotomy closure or vasovasostomy. AD - Departments of Urology, Surgery Pathology, New England Medical Center, Tufts University School of Medicine, Boston Department of Urology, Lemuel Shattuck Hospital, Boston, MA, United States Department of Urology, New England Medical Center, Box 389, 750 Washington Street, Boston. MA 02111, United States AU - Fallick, M. L. AU - Sable, D. B. AU - Faller, G. AU - Larock, D. AU - Sant, G. R. AU - Schlesinger, R. M. AU - Schwaitzberg, S. D. DB - Scopus DO - 10.1046/j.1464-410x.1997.28015.x IS - 1 KW - Dogs Sperm count Sterilization reversal Vasectomy M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 1997 SP - 70-73 ST - Histological evidence of an inflammatory reaction to suture material in the dog vas deferens T2 - British Journal of Urology TI - Histological evidence of an inflammatory reaction to suture material in the dog vas deferens UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031403625&doi=10.1046%2fj.1464-410x.1997.28015.x&partnerID=40&md5=28cd5cb24ecfee6ed15f900a9d34d9f6 VL - 79 ID - 1709 ER - TY - JOUR AB - This paper describes a polymer site-specific delivery system containing human growth hormone in an in vivo model of scarring in the diabetic state. Copolymer discs with the hormone were introduced into incisions made in rats previously injected with streptozotocin in order to induce diabetes. Tissue specimens for evaluation were obtained at 3, 7 or 10 days after the procedure. Study groups were healthy rats and diabetic rats untreated or treated with/without the hormone. Histological sections were prepared for light microscopy examination of wound zones. Three and 7 days after surgery, polymer remains could be observed in the subcutaneous tissue. These remnants induced a moderate foreign body reaction. The number of macrophages detected was directly related to neovessel formation and metalloelastase expression. The CD4+/CD8+ ratio was low during the initial follow up stages (3 and 7 days) in untreated diabetic rats, yet an increased ratio corresponding to areas around the polymer remains was noted in the animals treated with copolymer loaded with the growth hormone. Copolymer is biodegradable in vivo and may be used as a vehicle for the slow release of active substances. The presence of the hormone at the site of skin injury induces cell proliferation and enhances the repair process. AD - Department of Medical Especialities, Faculty of Medicine, University of Alcalá, Ctra N-II, Km 33.600, 28871 Alcala de Henares, Madrid, Spain Department of Surgery, Faculty of Medicine, University of Alcalá, Ctra N-II, Km 33.600, 28871 Alcala de Henares, Madrid, Spain Inst. of Science/Polymer Tecnology, CSIC, Madrid, Spain AU - García-Esteo, F. AU - Pascual, G. AU - García-Honduvilla, N. AU - Gallardo, A. AU - San-Román, J. AU - Bellón, J. M. AU - Buján, J. DB - Scopus IS - 1 KW - Diabetes Drug delivery Growth factor Immune response Wound healing M3 - Article N1 - Cited By :9 Export Date: 10 November 2020 PY - 2005 SP - 53-57 ST - Histological evaluation of scar tissue inflammatory response: The role of hGH in diabetic rats T2 - Histology and Histopathology TI - Histological evaluation of scar tissue inflammatory response: The role of hGH in diabetic rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-11144282040&partnerID=40&md5=a52461facf3f00b4b95a0eb42397e065 VL - 20 ID - 1618 ER - TY - JOUR AB - Drug-eluting vascular prostheses represent a new direction in vascular surgery to reduce early thrombosis and late intimal hyperplasia for small calibre grafts. Subcutaneous implantation in rats is a rapid and cost-effective screening model to assess the drug-elution effect and could, to some extent, be useful to forecast results for vascular prostheses. We compared biological and histological responses to scaffolds in different implantation sites. Polycaprolactone (PCL), paclitaxel-loaded PCL (PCL-PTX) and dexamethasone-loaded PCL (PCL-DXM) electrospun scaffolds were implanted subcutaneously and in an infrarenal abdominal aortic model in rats for up to 12 weeks. At the conclusion of the study, a histological analysis was performed. Cellular graft invasion revealed differences in the progression of cellular infiltration between PCL-PTX and PCL/PCL-DXM groups in both models. Cell infiltration increased over time in the aortic model compared to the subcutaneous model for all groups. Cell counting revealed major differences in fibroblast, macrophage and giant cell graft colonisation in all groups and models over time. Macrophages and giant cells increased in the PCL aortic model; whereas in the subcutaneous model these cell types increased only after three weeks or even decreased in the drug-eluting PCL groups. Other major findings were observed only in the aortic replacement such as extracellular matrix deposition and neo-angiogenesis. The subcutaneous implant model can be used for screening, especially when drug-eluting effects are studied. However, major histological differences were observed in cell type reaction and depth of cell penetration compared to the aortic model. Our results demonstrate that the implantation site is a critical determinant of the biological response. AD - Division of Clinical Pathology, University Hospital of Geneva, Geneva 1211, Switzerland. jean-christophe.tille@hcuge.ch. School of Pharmaceutical Sciences, University of Geneva, Geneva 1211, Switzerland. sarra.devalence@gmail.com. Department of Pharmacy-Drug Sciences, University of Bari "Aldo Moro", Bari 70125, Italy. delia.mandracchia@uniba.it. School of Pharmaceutical Sciences, University of Geneva, Geneva 1211, Switzerland. benjamin.nottelet@univ-montp1.fr. Department of Cardiovascular Surgery, Faculty of Medicine, University Hospital, Geneva 1211, Switzerland. ufficiostampa@hpg23.it. School of Pharmaceutical Sciences, University of Geneva, Geneva 1211, Switzerland. Robert.Gurny@unige.ch. School of Pharmaceutical Sciences, University of Geneva, Geneva 1211, Switzerland. Michael.Moeller@unige.ch. Department of Cardiovascular Surgery, Faculty of Medicine, University Hospital, Geneva 1211, Switzerland. Beat.Walpoth@hcuge.ch. AN - 29615579 AU - Tille, J. C. AU - de Valence, S. AU - Mandracchia, D. AU - Nottelet, B. AU - Innocente, F. AU - Gurny, R. AU - Möller, M. AU - Walpoth, B. H. C2 - PMC5831816 DA - Feb 20 DO - 10.3390/jdb4010011 DP - NLM ET - 2016/02/20 IS - 1 KW - biodegradable polymers drug release extracellular matrix foreign body reaction pathology tissue engineering vascular prosthesis LA - eng N1 - 2221-3759 Tille, Jean-Christophe Orcid: 0000-0002-2255-5918 de Valence, Sarra Mandracchia, Delia Nottelet, Benjamin Innocente, Francesco Gurny, Robert Möller, Michael Orcid: 0000-0002-5299-4436 Walpoth, Beat H Journal Article J Dev Biol. 2016 Feb 20;4(1):11. doi: 10.3390/jdb4010011. PY - 2016 SN - 2221-3759 ST - Histologic Assessment of Drug-Eluting Grafts Related to Implantation Site T2 - J Dev Biol TI - Histologic Assessment of Drug-Eluting Grafts Related to Implantation Site VL - 4 ID - 171 ER - TY - JOUR AB - Background: The most common complication experienced by patients who have undergone mammary implant surgery is capsular contracture. This matter concerns physicians and patients, but to date, there is no effective way to avoid this complication. Surgical intervention usually is required. In 2002, the use of zafirlukast, a leukotriene inhibitor (a drug used for asthma treatment), was reported for the treatment of capsular contracture, with good results. Methods: For this study, 30 female Wistar rats were used. These animals received two silicone implants each: one with a smooth surface and one with a textured surface. All the animals received daily intraperitoneal injections for 90 days and were divided as follows: control group (C) receiving only saline solution, experimental group 1 (E-I) receiving 1.25 mg/kg/day of zafirlukast, and experimental group 2 (E-II) receiving 5 mg/kg/day of zafirlukast. Histologic analysis used hematoxilin and eosin to verify vessels, capsule thickness, and inflammatory cells. Immunoistochemical analysis with smooth muscle anti-actin antibody was used for myofibroblast verification. Picro-Sirius under polarized light was used for collagen analysis. Results: Textured implant experimental groups presented smaller numbers of vessels, thinner capsules, lower collagen density, and smaller numbers of mastocytes and eosinophils than the control group. No significant differences were found in smooth surface implants, as compared with the control group. Conclusion: Zafirlukast reduced the occurrence of factors directly and indirectly connected with capsular contracture. © 2007 Springer Science+Business Media, LLC. AD - Department of Surgery, Federal University of São Paulo, Escola Paulista de Medicina (UNIFESP-EPM), R. Napoleao Barros, 715, 4 andar HSP, 04024-002, São Paulo, SP, Brazil Department of Pathology, Federal University of São Paulo, Escola Paulista de Medicina (UNIFESP-EPM), Rua Botucatu, 740, Vila Clemetino, 04023-900, São Paulo, SP, Brazil R. C. Botelho, 376, Jd Maria Izabel, 17515-240, Marilia, São Paulo, Brazil AU - Bastos, E. M. AU - Neto, M. S. AU - Alves, M. T. S. AU - Garcia, É B. AU - Santos, R. A. AU - Heink, T. AU - Pereira, J. B. AU - Ferreira, L. M. DB - Scopus DO - 10.1007/s00266-006-0257-7 IS - 5 KW - Breast implants Contracture Leukotriene antagonists Therapeutics Zafirlukast M3 - Article N1 - Cited By :46 Export Date: 10 November 2020 PY - 2007 SP - 559-565 ST - Histologic analysis of zafirlukast's effect on capsule formation around silicone implants T2 - Aesthetic Plastic Surgery TI - Histologic analysis of zafirlukast's effect on capsule formation around silicone implants UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-34548748726&doi=10.1007%2fs00266-006-0257-7&partnerID=40&md5=0ed7edfaa18a53edde402fd07a49f2da VL - 31 ID - 1554 ER - TY - JOUR AB - To assess the histologic reaction caused by biomaterial particles in different sizes around the bone-implant interface, we examined ultra-high molecular weight polyethylene (UHMWPE, average diameter of 11 μm), UHMWPE (99 μm), cobalt-chromium alloy (Co-Cr, 3.9 μm), stainless steel (SUS316L, 3.9 μm), alumina ceramics (3.9 μm), titanium alloy (Ti, 3.5 μm), Co-Cr (0.03 μm), and Ti (0.03 μm). After the longitudinal groove on a polymethylmethacrylate plug was filled with one type of the particles, the plug was inserted into the medullar canal of the distal end of rabbit femurs, and tissue block was resected 4 and 12 weeks after the insertion. Histiocytes were markedly accumulated around the particles of UHMWPE (11 μm), Co-Cr (3.9 μm), SUS316L (3.9 μm), Co-Cr (0.03 μm), and titanium alloy (0.03 μm). Around the UHMWPE particles (99 μm), a slight histiocytic reaction and bone formation were observed. Particles of alumina ceramics (3.9 μm) and titanium alloy (3.5 μm) which were in phagocytosable sizes also had few histiocytic reactions. Statistically, the material difference was more strongly related to the histiocyte reaction than to the particle size and calculated total surface area of particles. Our findings demonstrate that particles of different biomaterials and in different sizes induce different foreign-body histological reactions. A study was conducted to clarify the relationship between histiocyte reaction. For this study, ultra-high molecular weight polyethylene (UHMWPE), cobalt-chromium alloy (Co-Cr), stainless steel, alumina ceramics, titanium alloy, and Ti were examined. As a first step, the longitudinal groove on a polymethacrylate plug was filled with one type of the particles. Following this, the plug was inserted into the medullar canal of the distal end of rabbit femurs, and tissue block was resected four and twelve weeks after the insertion. The data obtained indicate that particles of different biomaterials and in different sizes induce different foreign-body histological reactions. AD - Department of Orthopaedic Surgery, Kyoto Pref. University of Medicine, Kamigyo-ku, Kawaramachi-Hirokoji, Kyoto 602-0841, Japan Department of Orthopaedic Surgery, Yokohama City Univ. Sch. of Medicine, Yokohama, Japan Dept. of Pathol. and Cell Regulation, Kyoto Pref. University of Medicine, Kyoto, Japan AU - Kubo, T. AU - Sawada, K. AU - Hirakawa, K. AU - Shimizu, C. AU - Takamatsu, T. AU - Hirasawa, Y. DB - Scopus DO - 10.1002/(SICI)1097-4636(19990615)45:4<363::AID-JBM11>3.0.CO;2-3 IS - 4 KW - Biomaterials Histological reaction Particle Size Surface area M3 - Article N1 - Cited By :57 Export Date: 10 November 2020 PY - 1999 SP - 363-369 ST - Histiocyte reaction in rabbit femurs to UHMWPE, metal, and ceramic particles in different sizes T2 - Journal of Biomedical Materials Research TI - Histiocyte reaction in rabbit femurs to UHMWPE, metal, and ceramic particles in different sizes UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033564003&doi=10.1002%2f%28SICI%291097-4636%2819990615%2945%3a4%3c363%3a%3aAID-JBM11%3e3.0.CO%3b2-3&partnerID=40&md5=7a407b110617c76afc42b4d257b783f3 VL - 45 ID - 1687 ER - TY - JOUR AD - Department of Medicine, Laniado Hospital, Sanz Medical Centre, Netanya, Israel Faculty of Medicine, Hebrew University and Hadassah Medical School, Jerusalem, Israel AU - Schattner, A. AU - Dubin, I. DB - Scopus DO - 10.1016/j.amjmed.2017.09.045 IS - 3 M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 SP - e91 ST - Hidden Malefactor: Occult Foreign Body in Diabetic Foot T2 - American Journal of Medicine TI - Hidden Malefactor: Occult Foreign Body in Diabetic Foot UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85034734794&doi=10.1016%2fj.amjmed.2017.09.045&partnerID=40&md5=6800bb4b08595f1fa310fcc1ee2e53e8 VL - 131 ID - 1085 ER - TY - JOUR AB - Retained surgical sponges are serious adverse events that can result in negative patient outcomes. The primary method of prevention is the sponge count. Searching for sponges to reconcile counts can result in inefficient use of OR time. The purpose of this descriptive study was to estimate the cost of nonproductive OR time (ie, time spent not moving forward with the surgical procedure) spent reconciling surgical sponge counts and the cost of using radiography to rule out the presence of retained sponges. We included 13,322 patient surgeries during a nine-month period. Perioperative personnel required from one to 90 minutes of additional time to reconcile each of 212 incorrect/unresolved counts. The total annualized cost of OR time spent searching for sponges and ruling out the presence of potentially retained sponges using radiography was $219,056. These costs should be included in comprehensive cost analyses when considering alternatives to supplement the surgical count. AN - 26514707 AU - Steelman, V. M. AU - Schaapveld, A. G. AU - Perkhounkova, Y. AU - Storm, H. E. AU - Mathias, M. DA - Nov DO - 10.1016/j.aorn.2015.09.002 DP - NLM ET - 2015/10/31 IS - 5 KW - Foreign Bodies/economics/*prevention & control *Health Care Costs Humans Medical Errors/*economics *Surgical Sponges cost medical/surgical errors patient safety retained surgical item retained surgical sponge LA - eng N1 - 1878-0369 Steelman, Victoria M Schaapveld, Ann G Perkhounkova, Yelena Storm, Hillary E Mathias, Michelle Journal Article United States AORN J. 2015 Nov;102(5):498-506. doi: 10.1016/j.aorn.2015.09.002. PY - 2015 SN - 0001-2092 SP - 498-506 ST - The Hidden Costs of Reconciling Surgical Sponge Counts T2 - Aorn j TI - The Hidden Costs of Reconciling Surgical Sponge Counts VL - 102 ID - 167 ER - TY - JOUR AB - Biomaterial-associated multinucleated giant cells (BMGCs) have been found within the implantation beds of many different biomaterials. However, their exact differentiation and their involvement in the inflammatory and healing events of the foreign body response still remain mostly unclear. Silk fibroin (SF) scaffolds, which induces a tissue reaction involving both macrophages and BMGCs, was implanted in the subcutaneous connective tissue of four CD-1 mice for 15 days using an established subcutaneous implantation model. Analysis of macrophage polarization and BMGCs was performed by immunohistochemcial detection of pro- (cyclooxygenase-2 (COX-2), C-C chemokine receptor type 7 (CCR7), nuclear factor "kappa-light-chain-enhancer" (NF-κB)) and anti-(heme oxygenase-1 (HO-1) and mannose receptor (MR, also known as CD206)). Furthermore, histochemical detection of tartrate-resistant acid phosphatase (TRAP) was conducted to test its predictive efficiency for the pro-inflammatory differentiation of cells. An established system for histomorphometrical analysis was used for counting of BMGCs expressing these molecules. The results show that BMGCs express both pro- and anti-inflammatory molecules within the implantation beds of SF scaffolds in comparable numbers, while only statistically significantly lower numbers of TRAP-positive BMGCs were measured in comparison to the BMGCs expressing the above-mentioned molecules. As these data substantiate the heterogeneity of BMGCs, the question arises to what extent BMGCs can "support" the process of tissue regeneration. Furthermore, the data prompt the question to what extent TRAP-expression within a biomaterial implantation bed can be seen as a predictive marker for an inflammatory condition, as in this study no obvious correlation between TRAP-expression and other pro-inflammatory markers could be observed. © 2015 Wiley Periodicals, Inc. AD - Clinic of Oro-Maxillofacial and Plastic Surgery, FORM-Lab, University Medical Center, Goethe University, Frankfurt, Germany Institute of Pathology, REPAIR-Lab, University Medical Center, Johannes Gutenberg University, Mainz, Germany Department of Materials Engineering and Industrial Technologies, BIOtech Research Centre, University of Trento, Trento, I-38050, Italy AU - Barbeck, M. AU - Motta, A. AU - Migliaresi, C. AU - Sader, R. AU - Kirkpatrick, C. J. AU - Ghanaati, S. DB - Scopus DO - 10.1002/jbm.a.35579 IS - 2 KW - biomaterial foreign body reaction heterogeneity inflammation macrophages multinucleated giant cells M3 - Article N1 - Cited By :29 Export Date: 10 November 2020 PY - 2016 SP - 413-418 ST - Heterogeneity of biomaterial-induced multinucleated giant cells: Possible importance for the regeneration process? T2 - Journal of Biomedical Materials Research - Part A TI - Heterogeneity of biomaterial-induced multinucleated giant cells: Possible importance for the regeneration process? UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84955197690&doi=10.1002%2fjbm.a.35579&partnerID=40&md5=c7fd6a3f1d4499e871a77b1970744c5c VL - 104 ID - 1192 ER - TY - JOUR AB - Objective: To analyze clinical features and outcomes of patients with hospital-acquired (HA) and healthcare-associated (HCA) Staphylococcus aureus bacteremia. Methods: A retrospective cohort study was conducted from 1988 to 2007. We compared patients with clinically significant HA with those with HCA S. aureus bacteremia. Risk factors for 30-day all-cause mortality were assessed using multivariable logistic regression analysis. Cox regression analysis was used to estimate the hazard ratio (HR) for 5-year mortality with 95% confidence intervals (CI). Results: Of 1261 episodes, 735 (58.3%) were HA and 526 (41.7%) were HCA. The percentage of MRSA was 48.2% (354/735) in HA vs. 42.2% (222/526) in HCA bacteremia; p= 0.04. The percentages of HCA S. aureus bacteremia and MRSA bacteremia did not vary throughout the study period. Mortality at 30 days was 40.2% (507/1261) and at 1 year was 63.4% (800/1261); this was comparable for HA and HCA bacteremia. Five-year survival curves in both settings followed very similar patterns (HR 1.01, 95% CI 0.89-1.15). Risk factors for 30-day mortality were similar, except for primary bacteremia and pre-existing heart valve disease in the HA group. Conclusions: HCA S. aureus bacteremia shares many similarities with HA bacteremia with respect to the prevalence of MRSA strains, mortality rates, and risk factors for death, and should be managed similarly. © 2012 International Society for Infectious Diseases. AD - Infectious Diseases Unit, Rabin Medical Center, Beilinson Hospital and Sackler School of Medicine, Tel-Aviv University, Petah-Tiqva, 49100, Israel Department of Medicine E, Rabin Medical Center, Beilinson Hospital and Sackler School of Medicine, Tel-Aviv University, Petah-Tiqva, Israel Laboratory of Clinical Microbiology, Rabin Medical Center, Beilinson Hospital and Sackler School of Medicine, Tel-Aviv University, Petah-Tiqva, Israel Pharmacy Services, Rabin Medical Center, Beilinson Hospital and Sackler School of Medicine, Tel-Aviv University, Petah-Tiqva, Israel AU - Bishara, J. AU - Goldberg, E. AU - Leibovici, L. AU - Samra, Z. AU - Shaked, H. AU - Mansur, N. AU - Paul, M. DB - Scopus DO - 10.1016/j.ijid.2012.02.009 IS - 6 KW - Healthcare Mortality MRSA Nosocomial Staphylococcus aureus M3 - Article N1 - Cited By :14 Export Date: 10 November 2020 PY - 2012 SP - e457-e463 ST - Healthcare-associated vs. hospital-acquired Staphylococcus aureus bacteremia T2 - International Journal of Infectious Diseases TI - Healthcare-associated vs. hospital-acquired Staphylococcus aureus bacteremia UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84860382381&doi=10.1016%2fj.ijid.2012.02.009&partnerID=40&md5=7bac9cd6354551a5e1188421f401f853 VL - 16 ID - 1369 ER - TY - JOUR AB - Objectives. The aim of this study was to analyze the cellular sources for the neointima and the cell type that is lining the lumen in artificial grafts implanted in pigs. Materials and methods. We used polytetrafluoroethylene grafts as bypasses from the common to the external iliac arteries. The animals were sacrificed after 1, 4, 7, 14, 21, 30, 60 and 90 days. Morphological, immunohistochemical and electron microscope assessments were made. Results. After 7 days a circumferential neoadventitia was formed. At day 14 isolated cellular islets of proliferating cells were observed on the luminal side of the graft without connection to the neoadventitia or the adjacent arteries. In the anastomotic regions at day 14 we observed an isolated neointima in contact with the adjacent artery. The cells lining the lumen had characteristics of both smooth muscle cells and endothelial cells. Conclusions. Our study suggests that in artificial porcine grafts, the perivascular tissue, the blood and the adjacent artery contribute to the formation of the neointima. The luminal surface is covered by a hybrid cell with both smooth muscle cell and endothelial cell properties. © 2005 Elsevier Ltd. All rights reserved. AD - Department of Vascular Surgery, Wallenberg Laboratory, Sahlgrenska Academy, Göteborg, Sweden The Electron Microscopy Unit, Institute of Anatomy and Cell Biology, Sahlgrenska Academy, Göteborg, Sweden Department of Hand Surgery, Uppsala University, Uppsala, Sweden Department of Vascular Surgery, Sahlgrenska University Hospital, Bruna Stråket 11B, SE-413 45 Gothenburg, Sweden AU - Mellander, S. AU - Fogelstrand, P. AU - Enocson, K. AU - Johansson, B. R. AU - Mattsson, E. DB - Scopus DO - 10.1016/j.ejvs.2005.02.051 IS - 1 KW - Cellular sources Hybrid cell Neointima Pig PTFE graft M3 - Article N1 - Cited By :8 Export Date: 10 November 2020 PY - 2005 SP - 63-70 ST - Healing of PTFE grafts in a pig model recruit neointimal cells from different sources and do not endothelialize T2 - European Journal of Vascular and Endovascular Surgery TI - Healing of PTFE grafts in a pig model recruit neointimal cells from different sources and do not endothelialize UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-20144370476&doi=10.1016%2fj.ejvs.2005.02.051&partnerID=40&md5=20235ce063991c61f3bd344aa84e3005 VL - 30 ID - 1606 ER - TY - JOUR AB - Foreign body ingestion is a common occurrence in the pediatric population. Frequent culprits include coins, toys, sharp objects and bones, which most often pass spontaneously. Magnet ingestion, however, can be a serious matter, especially when more than one is taken in. The extremely strong magnetic force between multiple magnets may result in numerous complications including bowel necrosis, perforation, obstruction, fistula formation, volvulus and death. We present the largest series reported to date, with four cases of multiple magnet ingestion at our institution with varied presentations and findings. We review the literature, and discuss the importance of having a high index of suspicion. © Georg Thieme Verlag KG Stuttgart. AD - Pediatric General Surgery, Children's Memorial Hospital, 2300 Children's Plaza, #63, Chicago, IL 60614, United States General Surgery, Rush University Medical Center, Chicago, IL, United States AU - Kabre, R. AU - Chin, A. AU - Rowell, E. AU - Browne, M. AU - Barsness, K. A. AU - Luck, S. AU - Jona, J. DB - Scopus DO - 10.1055/s-2008-1038824 IS - 3 KW - Bowel obstruction Foreign body ingestion Intestinal perforation Multiple magnet ingestion Volvulus M3 - Article N1 - Cited By :20 Export Date: 10 November 2020 PY - 2009 SP - 187-190 ST - Hazardous complications of multiple ingested magnets: Report of four cases T2 - European Journal of Pediatric Surgery TI - Hazardous complications of multiple ingested magnets: Report of four cases UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-70350520454&doi=10.1055%2fs-2008-1038824&partnerID=40&md5=fcb8cfe47ee9552034f6562c8dde9906 VL - 19 ID - 1493 ER - TY - JOUR AB - Purpose: To report the case of a patient with a damaged haptic of an acrylic intraocular lens (IOL) after transscleral IOL fixation. Methods: This is a retrospective and descriptive case report. Results: A 40-year-old man presented with sudden visual loss in the left eye. He had undergone phacoemulsification/aspiration and IOL implantation 3 years previously and IOL repositioning with transscleral fixation 2 years before the initial visit. His visual acuity was 0.3 in the left eye due to corneal edema caused by a foreign body, i.e., the severed haptic tip of the single-piece acrylic IOL, which was surgically removed. The IOL itself was tilted and therefore explanted. The surface of the tip of the haptic suggested that the monofilament suture thread had exerted continuous force across the haptic. Conclusions: The haptics of acrylic IOLs can be damaged after transscleral fixation. © 2014 S. Karger AG, Basel. AD - Department of Ophthalmology, National Hospital Organization, National Tokyo Medical Center, Japan Laboratory of Visual Physiology, National Institute of Sensory Organs, National Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-ku, Tokyo, 152-8902, Japan Department of Ophthalmology, Keio University, School of Medicine, Tokyo, Japan UCL Institute of Ophthalmology, London, United Kingdom AU - Tanaka, H. AU - Fujinami, K. AU - Watanabe, K. AU - Noda, T. AU - Akiyama, K. DB - Scopus DO - 10.1159/000365350 IS - 2 KW - Acrylic intraocular lens Intraocular lens Intraocular lens damage Transscleral fixation M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2014 SP - 212-216 ST - Haptic breakage after transscleral fixation of a single-piece acrylic intraocular lens T2 - Case Reports in Ophthalmology TI - Haptic breakage after transscleral fixation of a single-piece acrylic intraocular lens UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84929463534&doi=10.1159%2f000365350&partnerID=40&md5=7f4777230a27c947716824fecb596a08 VL - 5 ID - 1283 ER - TY - JOUR AN - 116404422. Language: English. Entry Date: 20160728. Revision Date: 20160728. Publication Type: Article DB - ccm DO - 10.1016/j.aorn.2016.04.011 DP - EBSCOhost IS - 1 KW - Retained Instruments -- Prevention and Control Practice Guidelines Perioperative Nursing Surgical Count Procedure N1 - practice guidelines. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Evidence-Based Practice; Patient Safety. NLM UID: 0372403. PY - 2016 SN - 0001-2092 SP - 49-53 ST - Guideline Summary: Prevention of Retained Surgical Items T2 - AORN Journal TI - Guideline Summary: Prevention of Retained Surgical Items UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=116404422&site=ehost-live&scope=site VL - 104 ID - 781 ER - TY - JOUR AB - A surgical item unintentionally retained in a patient after an operative or other invasive procedure is a serious, preventable medical error with the potential to cause the patient great harm. Perioperative RNs play a key role in preventing retained surgical items (RSIs). The updated AORN "Guideline for prevention of retained surgical items" provides guidance for implementing a consistent, multidisciplinary approach to RSI prevention; accounting for surgical items; preventing retention of device fragments; reconciling count discrepancies; and using adjunct technologies to supplement manual count procedures. This article focuses on key points of the guideline to help perioperative personnel provide optimal care during a procedure. Key points addressed include taking responsibility for RSI prevention as a team; minimizing distractions, noise, and interruptions during counts; using consistent counting methods; reconciling discrepancies; and participating in performance-improvement activities. Perioperative RNs should review the complete guideline for additional information and for guidance in writing and updating policies and procedures. AN - 27350354 AU - Fencl, J. L. DA - Jul DO - 10.1016/j.aorn.2016.05.005 DP - NLM ET - 2016/06/29 IS - 1 KW - Education, Nursing, Continuing Foreign Bodies/*prevention & control *Guidelines as Topic Humans count reconciliation incorrect count never event retained surgical item LA - eng N1 - 1878-0369 Fencl, Jennifer L Journal Article United States AORN J. 2016 Jul;104(1):37-48. doi: 10.1016/j.aorn.2016.05.005. PY - 2016 SN - 0001-2092 SP - 37-48 ST - Guideline Implementation: Prevention of Retained Surgical Items T2 - Aorn j TI - Guideline Implementation: Prevention of Retained Surgical Items VL - 104 ID - 178 ER - TY - JOUR AB - Background and purpose — Cutibacterium acnes, formerly known as Propionibacterium acnes, is often isolated from deep tissues of the shoulder. It is recognized as an important causative agent of foreign-material associated infections. However, the incidence and significance of its detection in tissues from patients without clinical evidence for infection is unclear. We assessed the incidence of C. acnes colonization of osteosynthesis material in asymptomatic patients, and evaluated the short-term outcome in relation to the microbiological findings. Patients and methods — We microbiologically analyzed osteosynthesis material of 34 asymptomatic patients after surgery on the clavicle. Material obtained from 19 asymptomatic patients after osteosynthesis of the fibula served as a control group. Patients were clinically followed up for 3–24 months after removal of the osteosynthesis material. Results — Bacteria were recovered from devices in 29 of 34 patients from the clavicle group. 27 of 29 positive samples grew C. acnes. Isolation of C. acnes was more common in male than in female patients. No bacterial growth was observed on foreign material from patients in the fibula group. All patients remained asymptomatic at follow-up. Interpretation — Growth of C. acnes is common on osteosynthesis material of the shoulder, especially in males. Samples were positive irrespective of clinical signs of infection. Therefore, detection of C. acnes in this clinical setting is of questionable clinical significance. The high positivity rate in asymptomatic patients discourages routine sampling of material in cases without clinical evidence for infection. © 2018, © 2018 The Author(s). Published by Taylor & Francis on behalf of the Nordic Orthopedic Federation. AD - Institut für Medizinische Mikrobiologie, Virologie und Hygiene, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany Klinik für Unfall- und Wiederherstellungschirurgie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany Institut für Pathologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany Zentrum für Orthopädie, Unfall- und Wirbelsäulenchirurgie, Asklepios Klinik Altona, Hamburg, Germany AU - Both, A. AU - Klatte, T. O. AU - Lübke, A. AU - Büttner, H. AU - Hartel, M. J. AU - Grossterlinden, L. G. AU - Rohde, H. DB - Scopus DO - 10.1080/17453674.2018.1489095 IS - 5 M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2018 SP - 580-584 ST - Growth of Cutibacterium acnes is common on osteosynthesis material of the shoulder in patients without signs of infection T2 - Acta Orthopaedica TI - Growth of Cutibacterium acnes is common on osteosynthesis material of the shoulder in patients without signs of infection UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85055186609&doi=10.1080%2f17453674.2018.1489095&partnerID=40&md5=4acf68075d327607b01ed933c9210179 VL - 89 ID - 1060 ER - TY - JOUR AB - While technology can provide new tools to help operating room staff reduce the risk of retained objects following a procedure, experts point out that a good count policy must be in place first.* Bar-coded sponges help nurses avoid counting the same sponge twice.* Policies should be clearly written and easily understood.* Keep things simple by requiring the same actions in every case of a miscount. AN - 105814223. Language: English. Entry Date: 20080919. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical DB - ccm DP - EBSCOhost IS - 4 KW - Bar Coding Patient Safety Surgical Instruments Academic Medical Centers -- Illinois Hospital Policies Illinois Surgical Count Procedure N1 - Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2008 SN - 0190-5066 SP - 41-43 ST - Grocery store technology finds place in OR: bar coding offers tool for counting sponges T2 - Same-Day Surgery TI - Grocery store technology finds place in OR: bar coding offers tool for counting sponges UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105814223&site=ehost-live&scope=site VL - 32 ID - 885 ER - TY - JOUR AB - Gingival pathology is a daily presentation, however a small number of systemic conditions can manifest similar to a common gingival condition and have fatal results. Dentist referred 56-year-old woman to Oral and Maxillofacial Surgery department with a 2-week medical history of gingival bleeding not responding to local measures. Biopsy showed eosinophilic infiltrate and vasculitis, and blood tests showed positive markers including cytoplasmic antineutrophil cytoplasmatic antibodies. Granulomatosis with polyangiitis is a rare disease affecting the respiratory tract, blood vessels and kidneys. Oral lesions are rarely the primary presenting feature. When left untreated, most cases are fatal within a year of diagnosis. The diagnosis can only be made when certain criteria are found, including granular oral lesions exhibiting an eosinophilic inflammatory infiltrate on biopsy. With 5% of cases showing intraoral lesions as the primary feature, it is essential that dentists have the knowledge of this rare disease to refer and not to treat as a common gingival condition. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ. AD - Oral Surgery, University College London Hospitals NHS Foundation Trust, London, United Kingdom Oral and Maxillofacial Surgery, Queen Victoria Hospital NHS Foundation Trust, East Grinstead, United Kingdom AU - Patrick, A. AU - Altman, K. C7 - e229607 DB - Scopus DO - 10.1136/bcr-2019-229607 IS - 4 KW - Dentistry and oral medicine Mouth Pathology Vasculitis M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 ST - Granulomatosis with polyangiitis: Potentially lethal gingival lesions presenting to the dentist T2 - BMJ Case Reports TI - Granulomatosis with polyangiitis: Potentially lethal gingival lesions presenting to the dentist UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065325860&doi=10.1136%2fbcr-2019-229607&partnerID=40&md5=6f1a78253289ff0a720ebdbaa8e099c8 VL - 12 ID - 1021 ER - TY - JOUR AB - PURPOSE:: To compare histometrically, in rats, the bone healing after grafting the incisor extraction sockets with inorganic bovine bone or bioactive glass particles. MATERIAL:: The volume fraction of grafted materials and alveolar healing components was estimated in histologic images at the end of the second and ninth weeks postoperatively by a differential point-counting method. RESULTS:: Both materials were histologically observed partially filling the cervical alveolar third and, although evoking neither a foreign body reaction nor a persisting inflammatory response, delayed new bone formation in trial areas around their particles. By the second week, the delay in bone healing was more pronounced in the animals grafted with inorganic than in those grafted with bioactive glass, and an opposing result was observed during a 9-week period. CONCLUSION:: Both inorganic bovine bone and bioactive glass particles grafted in the incisor extraction sockets of rats delayed new bone formation, and the degree of impairment resulted from a combination of factors such as type of material and phase of the reparation process. Copyright © Lippincott Williams & Wilkins. AD - Dental School of Ribeirão Preto-USP, Ribeirão Preto, SP, Brazil Department of Pathology, Claretiano University Center, Ceuclar, Batatais, SP, Brazil Department of Morphology, Stomatology and Physiology, Dental School of Ribeirão Preto-USP, Ribeirão Preto, SP, Brazil Departamento de Morfologia Estomatologia e Fisiologia, Faculdade de Odontologia de Ribeirão Preto-USP, Av. do Café S/N, 14040-904 Ribeirão Preto, SP, Brazil AU - Calixto, R. F. E. AU - Teófilo, J. M. AU - Brentegani, L. G. AU - Lamano-Carvalho, T. L. DB - Scopus DO - 10.1097/ID.0b013e3180500b95 IS - 3 KW - Alveolar healing Bioactive glass Bone healing Inorganic bovine bone graft M3 - Article N1 - Cited By :9 Export Date: 10 November 2020 PY - 2007 SP - 260-269 ST - Grafting of tooth extraction socket with inorganic bovine bone or bioactive glass particles: Comparative histometric study in rats T2 - Implant Dentistry TI - Grafting of tooth extraction socket with inorganic bovine bone or bioactive glass particles: Comparative histometric study in rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-34548587272&doi=10.1097%2fID.0b013e3180500b95&partnerID=40&md5=38ab325abbad5f33f3bc862ccbd4f8a2 VL - 16 ID - 1555 ER - TY - JOUR AB - BACKGROUND: Intermittently, the incidence of retained surgical items after surgery is reported in the healthcare literature, usually in the form of case studies. It is commonly recognised that poor communication practices influence surgical outcomes. AIM: To explore the power relationships in the communication between nurses and surgeons that affect the conduct of the surgical count. METHODS: A qualitative, ethnographic study was undertaken. Data were collected in three operating room departments in metropolitan Melbourne, Australia. 11 operating room nurses who worked as anaesthetic, instrument and circulating nurses were individually observed during their interactions with surgeons, anaesthetists, other nurses and patients. Data were generated through 230 h of participant observation, 11 individual and 4 group interviews, and the keeping of a diary by the first author. A deconstructive analysis was undertaken. RESULTS: Results are discussed in terms of the discursive practices in which clinicians engaged to govern and control the surgical count. The three major issues presented in this paper are judging, coping with normalisation and establishing priorities. CONCLUSIONS: The findings highlight the power relationships between members of the surgical team and the complexity of striking a balance between organisational policy and professional judgement. Increasing professional accountability may help to deal with the issues of normalisation, whereas greater attention needs to be paid to issues of time management. More sophisticated technological solutions need to be considered to support manual counting techniques. AD - School of Nursing, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Carlton, Victoria, Australia. robin.riley@easternhealth.org.au AN - 17074876 AU - Riley, R. AU - Manias, E. AU - Polglase, A. C2 - PMC2565825 DA - Oct DO - 10.1136/qshc.2005.017293 DP - NLM ET - 2006/11/01 IS - 5 KW - Adult Anesthesiology Anthropology, Cultural Cooperative Behavior Foreign Bodies/*prevention & control General Surgery *Guideline Adherence Hospitals, Urban/standards Humans *Interdisciplinary Communication Medical Errors/*prevention & control Middle Aged Operating Room Nursing/*standards Organizational Policy *Physician-Nurse Relations *Power, Psychological Professional Autonomy Qualitative Research Safety Management/*standards Surgical Instruments/supply & distribution Surgical Sponges/supply & distribution Victoria LA - eng N1 - 1475-3901 Riley, R Manias, E Polglase, A Journal Article Research Support, Non-U.S. Gov't Qual Saf Health Care. 2006 Oct;15(5):369-74. doi: 10.1136/qshc.2005.017293. PY - 2006 SN - 1475-3898 (Print) 1475-3898 SP - 369-74 ST - Governing the surgical count through communication interactions: implications for patient safety T2 - Qual Saf Health Care TI - Governing the surgical count through communication interactions: implications for patient safety VL - 15 ID - 61 ER - TY - JOUR AB - PURPOSE OF REVIEW: Gossypibomas remain a dreaded and unwanted complication of surgical practice. Despite significant interest and numerous guidelines, the number of reported cases remains sparse due to various factors, including potential legal implications. Herein, we review related data from India to ascertain if the problem is better or worse than that reported in world literature. MATERIALS AND METHODS: A literature search was performed on PubMed and Google Scholar, to collect and analyze all case reports and case reviews regarding the condition in India. RESULTS: On analysis of the results, there were 100 publications reporting a total of 126 events. The average patient age was 38.65 years. Average time to discovery was 1225.62 days. Forty-nine percent of reported cases were discovered within the 1 st year. The most common clinical features were pain (73.8%), palpable mass (47.6%), vomiting (35%), abdominal distention (26%), and fever (12.6%). Spontaneous expulsion of the gossypiboma was noted in five cases (3.96%). Transmural migration was seen in 36 cases (28.57%). CONCLUSIONS: Despite advancements in surgical approaches and preventive measures, gossypibomas continue to be a cause of significant morbidity. A safe working culture, open communication, teamwork, and an accurate sponge count remain our best defence against this often unpredictable complication of surgery. AD - Department of General Surgery, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India. Department of Forensic Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India. AN - 28079043 AU - Patial, T. AU - Thakur, V. AU - Vijhay Ganesun, N. AU - Sharma, M. C2 - PMC5394815 DA - Jan-Mar DO - 10.4103/0022-3859.198153 DP - NLM ET - 2017/01/13 IS - 1 KW - *Foreign Bodies Humans India *Postoperative Complications LA - eng N1 - 0972-2823 Patial, T Thakur, V Vijhay Ganesun, N Sharma, M Journal Article Systematic Review J Postgrad Med. 2017 Jan-Mar;63(1):36-41. doi: 10.4103/0022-3859.198153. PY - 2017 SN - 0022-3859 (Print) 0022-3859 SP - 36-41 ST - Gossypibomas in India - A systematic literature review T2 - J Postgrad Med TI - Gossypibomas in India - A systematic literature review VL - 63 ID - 187 ER - TY - JOUR AB - The term "gossypiboma" denotes foreign bodies retained after surgery. The most common gossypiboma is the iatrogenic surgical sponge. Usually, hysterectomy, appendectomy and cholecystectomy operations are associated with these retained sponges. They may be misdiagnosed as incisional endometriosis. We present a patient who had a caesarean section operation eleven years ago with a mass at the abdominal wall between the umbilicus and the caesarean section scar on the left paramedian region approximately 5 x 2 cm in diameter. We must keep in mind that prevention is more important for cure. As we knew that most reported cases occur in the presence of a normal pack count, we think that the surgical team must be very careful in the operation room. AD - E. Ilter, Maltepe Universtiy, Faculty of Medicine, Department of Gynecology and Obstetrics, Istanbul, Turkey AU - Ilter, E. AU - Manukyan, M. N. AU - Haliloǧlu, B. AU - Çelik, A. AU - Özden, S. DB - Embase IS - 1 KW - abdominal pain adult article case report cesarean section cholecystectomy cholelithiasis clinical examination echography endometrium tumor female foreign body gauze dressing gossypiboma human laparoscopic surgery treatment outcome LA - English M3 - Article N1 - L358624311 2010-04-22 2010-05-24 PY - 2010 SN - 1300-0306 SP - 64-66 ST - Gossypiboma: A lesson to learn: Case report T2 - Turkiye Klinikleri Jinekoloji Obstetrik TI - Gossypiboma: A lesson to learn: Case report UR - https://www.embase.com/search/results?subaction=viewrecord&id=L358624311&from=export http://jinekoloji.turkiyeklinikleri.com/download_pdf.php?id=57196 VL - 20 ID - 565 ER - TY - JOUR AB - A gossypiboma is a mass within a patient's body comprising a cotton matrix surrounded by a foreign body granuloma. We describe an unusual presentation of a gossypiboma presenting in a 32-year-old man with acute epigastric pain and haematemesis. His surgical history revealed an emergency laparotomy following a road traffic accident 16 years ago. Initial gastroscopy showed extrinsic stomach compression. An abdominal ultrasound scan followed by a CT scan evidenced a large, well-defined, predominantly cystic mass with some solid areas occupying the left hypochondrium. Conservative management with insertion of a percutaneous drain proved to be inefficient. A laparotomy was performed; intraoperatively, the cyst was found to be ruptured and within it, a large surgical gauze was found. This was removed but required a distal pancreatectomy and gastrectomy for complete excision. He was discharged on day 74 of admission with outpatient follow-up. © BMJ Publishing Group Limited 2018. AD - General Surgery Department, Whipps Cross University Hospital, London, United Kingdom AU - De Gea Rico, A. AU - Krishna, P. AU - Devlin, H. L. AU - Rohatgi, A. C7 - 221537 DB - Scopus DO - 10.1136/bcr-2017-221537 KW - Gastrointestinal surgery Surgery M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 ST - Gossypiboma: A ghastly find T2 - BMJ Case Reports TI - Gossypiboma: A ghastly find UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054133790&doi=10.1136%2fbcr-2017-221537&partnerID=40&md5=3704e7b3cc045015e3f84ee0366eb586 VL - 2018 ID - 1092 ER - TY - JOUR AB - BACKGROUND: Gossypiboma (retained surgical sponge) is a rare medical event. It could cause a serious complication that can threaten patients' life. Its diagnosis is usually difficult because the clinical symptoms are nonspecific and the imaging findings are often inconclusive. CASE PRESENTATIONS: We present two cases, a 32 years old woman who passed a retained surgical sponge via rectum 5 months after cesarean section and a 30 years old lady presented with an acute abdomen that later found to have localized right lower quadrant abscess with a retained surgical sponge. CONCLUSION: The most important approach to reduce the incidence of gossypiboma is prevention. At the end of the surgery, a correct count is always the gold standard safeguard against it. Although errors are not to be completely avoided, continuous CPD and strict adherence to rules of the operating room will reduce its incidence to a minimum. AD - Cardiothoracic Unit, Department of Surgery, School of Medicine, College of Health Sciences, Addis Ababa University, Ethiopia. AN - 32116444 AU - Alemu, B. N. AU - Tiruneh, A. G. C2 - PMC7036463 DA - Jan DO - 10.4314/ejhs.v30i1.19 DP - NLM ET - 2020/03/03 IS - 1 KW - Gossypiboma abdominal abscess foreign body retained surgical sponge LA - eng N1 - 2413-7170 Alemu, Berhanu N Tiruneh, Abraham G Case Reports Ethiop J Health Sci. 2020 Jan;30(1):147-149. doi: 10.4314/ejhs.v30i1.19. PY - 2020 SN - 1029-1857 (Print) 1029-1857 SP - 147-149 ST - Gossypiboma: A Case Series and Literature Review T2 - Ethiop J Health Sci TI - Gossypiboma: A Case Series and Literature Review VL - 30 ID - 243 ER - TY - JOUR AB - INTRODUCTION: Post-operative complications in surgery may frequently be unavoidable. However, some complications result from human error, both in the intra-operative and post-operative period. One such complication, which is frequently underreported, is the retained swab, or gossypiboma. CASE REPORT: We report a case from our hospital of a patient who presented with unexplained pyrexia, 4 years post-gynaecological surgery in another institution. A 67-year-old woman from overseas presented to our emergency department with a 2-day-history of pyrexia, collapse and confusion. Following a CT guided biopsy, which was inconclusive, she was scheduled for retroperitoneal biopsy. In theatre, a retained swab was discovered. CONCLUSION: Prevention of gossypiboma is far better than cure. Strict adherence to swab counts, and the avoidance of change of staff during procedures is important in decreasing the incidence. Perhaps, with the increasing use of minimally invasive procedures, the incidence of gossypiboma will fall dramatically. AD - Division of Minimally Invasive Surgery, Department of General and Vascular Surgery, Adelaide and Meath Hospital, Tallaght, Dublin 24, Ireland. fionamaireadkiernan@yahoo.co.uk AN - 18820991 AU - Kiernan, F. AU - Joyce, M. AU - Byrnes, C. K. AU - O'Grady, H. AU - Keane, F. B. AU - Neary, P. DA - Dec DO - 10.1007/s11845-008-0197-0 DP - NLM ET - 2008/09/30 IS - 4 KW - Aged Confusion/etiology Female Fever/etiology Foreign Bodies/complications/*surgery Gynecologic Surgical Procedures/*adverse effects Humans Iatrogenic Disease *Medical Errors Risk Factors Surgical Instruments/*adverse effects Surgical Sponges/*adverse effects LA - eng N1 - 1863-4362 Kiernan, F Joyce, M Byrnes, C K O'Grady, H Keane, F B V Neary, P Case Reports Journal Article Review Ireland Ir J Med Sci. 2008 Dec;177(4):389-91. doi: 10.1007/s11845-008-0197-0. Epub 2008 Sep 27. PY - 2008 SN - 0021-1265 SP - 389-91 ST - Gossypiboma: a case report and review of the literature T2 - Ir J Med Sci TI - Gossypiboma: a case report and review of the literature VL - 177 ID - 83 ER - TY - JOUR AB - Objective: Gossypiboma or retained surgical textile is an ubiquitous medical error that is avoidable. It can cause serious morbidity and possibly even mortality. Because it is not anticipated, it is frequently misdiagnosed, and often-unnecessary radical surgical procedures are performed. It should be considered in the differential diagnosis of any postoperative case with unresolved or unusual problems. We report a woman with severe malabsorbtion signs caused by a gossypiboma. Methods: 35 year old woman who admitted to our clinic with abdominal pain, severe waterry diarrhea of 10 stools/day and weight lose with a duration of 6 months. She had a cesarean operation 7 months ago. The patients complaints started after the cesarean operation. Body mass index was 34.3 kg/cm2 (88 kg/ 160 cm). In her physical examination she had a pale skin and she had marked edema in the pretibial areas. Abdominal examination did not reveal a palpable organ or mass as she was obese. In laboratory tests hemoglobin was 8 gr/dl (mcv 69), wbc and plt counts were in the normal range. Albumin was 1.6 gr/dl with normal fasting glucose, liver and renal function tests. INR was in the normal range. Serum Ferritin, B12 levels were markedly low. Tumour markers were in the normal range. Abdominal ultrasound revealed fatty liver, marked ascites in the abdomen. Intestinal walls were markedly thickened and there was an unidetified mass between intestinal walls. Upper gastrointestinal endoscopy findings were not spesific except in the duodenum there was marked white dotting in the mucosa showing intestinal lymphangiectasia while in colonoscopy all the colon and the terminal ileum wall had edema obscuring the vasculature. Results: Abdominal CT and MRI revealed a mass in the right lower quadrant suggesting a closed perforation or a pericaecal abcess. Laparotomy revealed an encapsulated mass of 10 cm in diameter surrounded by omentum, which was removed. The mass turned out to be a forgotten surgical towel used during the previous operation. We could not identify the situation before the operation because the material did not have a radio-opaque marker. Postoperative course was uneventful. Conclusion: Retained surgical materials are seldom reported due to medicolegal implications. Although it is a rare situation in routine clinical practice, Gossypiboma should be considered as a differential diagnosis in the patients who had a diagnosis of intestinal lymphangiectasia and malabsorption. As Gossypiboma may lead to situations which cause mortality, all precautions should be taken to prevent it. Altough human errors cannot be completely abolished, continuous medical training and strict adherence to regulations should reduce the incidence to a minimum. New technologies are needed which will hopefully decrease the incidence of retained foreign bodies. An electronic article surveillance system which uses a tagged surgical sponge that can be identified electronically can be developed. Bar codes can be applied to all sponges, and with the use of a bar code scanner the sponges can be counted on the back table. (Figure Presented). AD - I. Tuzcuoglu AU - Tuzcuoglu, I. AU - Karatas, I. AU - Acilar, K. DB - Embase DO - 10.1111/jgh.12363_2 KW - glucose albumin cyanocobalamin tumor marker hemoglobin marker human gynecologist gastroenterology case report Asian intestine mortality female patient intestine wall edema intestine lymphangiectasia differential diagnosis textile body mass surgical technique examination diarrhea malabsorption weight liver kidney function test physical examination skin fatty liver abdomen laboratory test leukocyte abdominal pain diet restriction morbidity medical error ferritin blood level ultrasound colonoscopy ascites gastrointestinal endoscopy mucosa duodenum hospital ileum vascularization perforation laparotomy omentum telecommunication clinical practice diagnosis error medical education technology foreign body surgical sponge nuclear magnetic resonance imaging international normalized ratio LA - English M3 - Conference Abstract N1 - L71212918 2013-11-08 PY - 2013 SN - 0815-9319 SP - 157 ST - Gossypiboma-a gynecologist's legacy-case report of gossypiboma with severe malabsorbtion T2 - Journal of Gastroenterology and Hepatology TI - Gossypiboma-a gynecologist's legacy-case report of gossypiboma with severe malabsorbtion UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71212918&from=export http://dx.doi.org/10.1111/jgh.12363_2 VL - 28 ID - 472 ER - TY - JOUR AB - A gossypiboma is a mass of cotton sponge left in the body postoperatively. Here, we report a case of gossypiboma with bleeding through a fistula to the colon, which became clinically evident 24 years after gynecological surgery, and resembled a bleeding diverticulum at colonoscopy. A 67-year-old woman presented with anemia and hematochezia. She had undergone a hysterectomy for myoma uteri 24 years earlier. Colonoscopy showed a deep depressed lesion mimicking a diverticulum with bleeding in the transverse colon. A contrast-enhanced computed tomography was interpreted as revealing a 6-cm thick-walled tumor, containing an air bubble, and a fistula between the mass and the transverse colon. The patient underwent laparotomy, with the preoperative expectation that the mass was a penetrating submucosal tumor. Pathological findings revealed denatured cotton tissues surrounded by reactive tissues to the foreign body. Despite its rarity, gossypiboma should be considered in patients with an intra-abdominal mass who have a history of laparotomy. Gossypiboma can cause fistula to the colon and bleeding. Imaging studies and the clinical course may mimic a malignant tumor. © 2016, Japanese Society of Gastroenterology. AD - Department of Gastroenterology and Hepatology, Kurashiki Central Hospital, 1-1-1 Miwa, Kurashiki, Okayama 710-8602, Japan AU - Nishimura, N. AU - Mizuno, M. AU - Shimodate, Y. AU - Doi, A. AU - Mouri, H. AU - Matsueda, K. AU - Yamamoto, H. DB - Scopus DO - 10.1007/s12328-016-0699-7 IS - 1 KW - Bleeding Colonoscopy Fistula Gossypiboma M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2017 SP - 37-40 ST - Gossypiboma with bleeding from fistula to the colon observed by colonoscopy T2 - Clinical Journal of Gastroenterology TI - Gossypiboma with bleeding from fistula to the colon observed by colonoscopy UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84994213394&doi=10.1007%2fs12328-016-0699-7&partnerID=40&md5=99bb949f2b666cf31dcc36b34944b7ee VL - 10 ID - 1146 ER - TY - JOUR AB - A case of 36 year old Po+1 with retained abdominal gauze pack following myomectomy necessitating, exploratory laparatomy is presented. The need to pay attention to counting of instruments and gauze packs before closing the abdomen coupled with use of gauze impregnated with radio-detectable material is emphasized. AD - Department of Surgery, Ladoke Akintola University of Technology (LAUTECH), Teaching Hospital, Oshogbo, Nigeria AU - Fadiora, S. O. AU - Komolafe, J. O. AU - Ogunniyi, S. O. DB - Scopus IS - 1 M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2003 SP - 52-56 ST - Gossypiboma simulating huge ovarian mass: a case report T2 - Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria TI - Gossypiboma simulating huge ovarian mass: a case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0141431071&partnerID=40&md5=0f583c96e4a3f23ca893b3cd5790abb7 VL - 12 ID - 1649 ER - TY - JOUR AB - INTRODUCTION: Leaving a surgical item inside the patient at the end of surgery, is one of the most dreadful complications. The item is frequently a surgical sponge and the resultant morbidity is usually severe. Additionally, the event poses considerable psychic strain to the operating team, notably the surgeon. PRESENTATION OF CASES: Here we describe the clinical course of three patients in whom a surgical sponge was missed, despite a seemingly correct count at the end of difficult caesarean sections. In two patients, who presented shortly after surgery, the pad was extracted with no bowel resection. In the third patient, who presented several years after surgery, colectomy was performed. DISCUSSION: Gossypiboma is under reported and the true incidence is largely unknown. Depending on the body reaction and the characters of the retained sponge, the patient may present within months to years after surgery. Risk factors for retained foreign objects include emergency surgery, an unplanned change in the surgical procedure, higher body mass index, multiple surgical teams, greater number of major procedures done at the same time and incorrect count recording. The surgical procedure needed to extract the retained sponge may be a simple one, as in the first case, or it may be more complex, as seen in the other two cases. Although holding the correct count at the end of surgery is the gold standard safeguard against this mishap, human errors continue to occur, as happened in our patients. For that reason, the correct count should be supplemented by employing one of the several new technologies currently available. CONCLUSION: Gossypiboma continues to occur, despite precautionary measures. As its consequences might cost the patient his life and the surgeon his professional reputation, extra preventive measures should be sought and implemented. New advances in technology should be incorporated in the theatre protocol as additional safeguard against human error. When encountered, a direct incision over the encapsulated swelling, in contrast to a formal laparotomy incision, might simplify the surgical procedure. AD - Department of Surgery, Aseer Central Hospital-Abha, Saudi Arabia. Electronic address: ezzedien@hotmail.com. Department of Surgery, Aseer Central Hospital-Abha, Saudi Arabia. AN - 26741272 AU - Rabie, M. E. AU - Hosni, M. H. AU - Al Safty, A. AU - Al Jarallah, M. AU - Ghaleb, F. H. C2 - PMC4756180 DO - 10.1016/j.ijscr.2015.12.032 DP - NLM ET - 2016/01/08 KW - Gossypiboma Prevention Retained object LA - eng N1 - 2210-2612 Rabie, M Ezzedien Hosni, Mohammad Hassan Al Safty, Alaa Al Jarallah, Manea Ghaleb, Fadel Hussain Journal Article Int J Surg Case Rep. 2016;19:87-91. doi: 10.1016/j.ijscr.2015.12.032. Epub 2015 Dec 23. PY - 2016 SN - 2210-2612 (Print) 2210-2612 SP - 87-91 ST - Gossypiboma revisited: A never ending issue T2 - Int J Surg Case Rep TI - Gossypiboma revisited: A never ending issue VL - 19 ID - 168 ER - TY - JOUR AB - Gossypiboma is the term used to refer to a mass formed by surgical material left in the body cavity after surgery. We present the case of a middle-aged woman with a history of rheumatoid arthritis controlled with corticosteroids and biologic therapies, uncontrolled type II diabetes mellitus, and cesarean section with postoperative bleeding eight years earlier, who presents with right lower quadrant abdominal pain and is found to have a gossypiboma from her previous operation. A subsequent operation is undertaken to remove the gossypiboma. After the procedure, our patient's diabetes and chronic back pain greatly improve, raising the question of gossypiboma's role in these diseases. A review of our patient's records found that a correct sponge count was recorded after her cesarean section, raising questions about the operating room policies regarding surgical counts, the presence of falsely correct counts, and the need for postoperative plain films in procedures with an increased risk of a retained object. Our patient's presentation eight years after the inciting surgery raises questions about the involvement her immunosuppressive therapy may have had in cloaking the gossypiboma. Our case also raises the question of surgical culpability, including the ethical and legal considerations for apology from the culpable surgeon. AD - University of Washington School of Medicine, 1959 NE Pacific St, Seattle, WA 98195, USA. Coulee Medical Center, 411 Fortuyn Road, Grand Coulee, WA 99133, USA. AN - 29109890 AU - Unruh, K. AU - Hsieh, H. S. S. C2 - PMC5646340 DO - 10.1155/2017/3239093 DP - NLM ET - 2017/11/08 LA - eng N1 - 2090-6919 Unruh, Kenley Orcid: 0000-0001-9294-5383 Hsieh, Hsien Sing Sam Orcid: 0000-0003-3944-9932 Case Reports Case Rep Surg. 2017;2017:3239093. doi: 10.1155/2017/3239093. Epub 2017 Oct 3. PY - 2017 SN - 2090-6900 (Print) SP - 3239093 ST - Gossypiboma Resection after Eight Years in a Patient with Rheumatoid Arthritis and Diabetes T2 - Case Rep Surg TI - Gossypiboma Resection after Eight Years in a Patient with Rheumatoid Arthritis and Diabetes VL - 2017 ID - 201 ER - TY - JOUR AB - Gossypiboma Abstract Background: “Gossypiboma”, or “textiloma” denotes a mass of cotton that is retained in the body following surgery. Gossypiboma is a medico-legal problem especially for surgeons. To the best of our knowledge, the patient presented herein is the first reported patient in whom it mimicked a tumour and following a nephrectomy. Case presentation: A 46-year-old woman presented with right flank pain, for 6 months following a right nephrectomy in 2005 for a non-functioning kidney (biopsy unavailable). On examination abdomen was non-tender and non-distended. An ill-defined non-tender mass was palpable on bimanual examination in the right hypochondrium and lumbar region. A Pfannensteil and right flank scar were present. Plain abdominal radiography did not show any sign of a radio-opaque marker in the abdomen. However, contrast enhanced abdominal computerized tomography revealed a well-defined heterogenous spherical, soft-tissue mass of 13 x 9 x 9cm size in the right renal fossa, with a dense, enhanced wall, abutting the right psoas muscle and right posterior abdominal wall. Right adrenal and contralateral kidney appeared normal. Surgical excision was done which revealed an abdominal sponge surrounded by foreign body granuloma, densely adherent to surrounding structures. Conclusions: Gossypiboma, though rare, can mimick a tumour, and is a diagnostic challenge. There should be a high index of suspicion in patients who have previously been operated and present with non specific complaints and equivocal imaging findings. Prevention is by meticulous count of surgical materials and by use radio-opaque marker impregnated sponges and gauze. AD - A.J.P. George, CMC Vellore, Vellore, India AU - George, A. J. P. AU - Mukha, R. P. AU - Kekre, N. S. DB - Embase KW - marker human case report society India neoplasm patient examination telecommunication kidney abdomen nephrectomy surgery computer assisted tomography psoas muscle biopsy flank pain cotton abdominal radiography scar female hypochondriasis surgeon imaging soft tissue diagnosis abdominal wall adrenal gland excision foreign body granuloma prevention LA - English M3 - Conference Abstract N1 - L71491413 2014-06-13 PY - 2014 SN - 0970-1591 SP - S159 ST - Gossypiboma mimicking a retroperitoneal tumour: A case report and review of literature T2 - Indian Journal of Urology TI - Gossypiboma mimicking a retroperitoneal tumour: A case report and review of literature UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71491413&from=export VL - 30 ID - 466 ER - TY - JOUR AB - BACKGROUND: Gossypiboma is the term for a surgical complication resulting from foreign materials such as a surgical sponge or gauze that was accidentally left inside a patient's body. CASE REPORT: Here, we report the case of a 62-year-old woman with gossypiboma. She underwent surgery due to an abdominal mass that was preoperatively considered a tumor. Intra-postoperatively, it was diagnosed as gossypiboma. CONCLUSIONS: For the prevention of gossypiboma during the pre-operative and post-operative periods, counting sponges and surgical equipment must be done very carefully. If there is any doubt postoperatively, direct abdominal imaging may be helpful. AD - Department of General Surgery, Erzincan University, Erzincan, Turkey. Department of Radiology, Erzincan University, Erzincan, Turkey. Department of Pathology, Erzincan University, Erzincan, Turkey. AN - 26768016 AU - Eken, H. AU - Soyturk, M. AU - Balci, G. AU - Firat, D. AU - Cimen, O. AU - Karakose, O. AU - Somuncu, E. C2 - PMC4718114 DA - Jan 15 DO - 10.12659/ajcr.896717 DP - NLM ET - 2016/01/16 KW - *Abdomen Abdominal Neoplasms/diagnosis Diagnosis, Differential Female Foreign Bodies/*diagnosis Humans Middle Aged LA - eng N1 - 1941-5923 Eken, Huseyin Soyturk, Mehmet Balci, Gurhan Firat, Deniz Cimen, Orhan Karakose, Oktay Somuncu, Erkan Case Reports Journal Article Am J Case Rep. 2016 Jan 15;17:27-30. doi: 10.12659/ajcr.896717. PY - 2016 SN - 1941-5923 SP - 27-30 ST - Gossypiboma Mimicking a Mesenchymal Tumor: A Report of a Rare Case T2 - Am J Case Rep TI - Gossypiboma Mimicking a Mesenchymal Tumor: A Report of a Rare Case VL - 17 ID - 169 ER - TY - JOUR AB - Background & Objectives: The oblivion of surgical compresses during abdominal operations can lead to serious complications, such as gossypiboma. To report a case of a patient with gossypiboma. Methods: A 59-year-old woman, previously submitted to appendectomy and videolaparoscopic cholecystectomy. It evolved postoperatively with flank obstruction. She underwent exploratory laparotomy for lysis of the flanges and adhesions. She sought care two days after hospital discharge with distention and severe abdominal pain, nausea and vomiting. Autopsy was made. Results: At the autopsy, a large amount of purulent fluid and a surgical compress adhered to the intestinal loops were seen in the abdominal cavity. Adjacent to this dressing, reddish areas with blackened foci were noted. The body was then referred to the Institute that performs medicallegal autopsies.The oblivion of foreign bodies during abdominal operations represents a serious complication, estimating an incidence of 1 for every 1000-1500 laparotomies and generates inflammatory tissue activity in its environment which can culminate in septic / exudative or aseptic / fibrinous reaction. Most of the time, the diagnosis is only established during the operative procedure for intestinal clearing or during the autopsy. Conclusion: In summary, it was possible to observe that the forgetting of foreign bodies during surgeries leads to significant harm to the patients, often culminating in death. However, there are simple and effective mechanisms to avoid this event, such as adherence to the protocol of safe surgery whose one of the principles is the counting of the surgical material before the patient leaves the operating room. AD - J. Melo, Department of Pathology, Faculty of Medicine, University of Fortaleza, Brazil AU - Melo, J. AU - Ribeiro Pontes, G. AU - Moita Mota, H. AU - Nobre Cavalcanti Lucas, G. AU - Nunes Oliveira, D. AU - Texeira De Souza, I. DB - Embase DO - 10.1007/s00428-019-02631-8 KW - abdominal cavity abdominal pain adult appendectomy autopsy case report cholecystectomy clinical article complication compress conference abstract female foreign body hospital discharge human incidence intestine loop laparotomy middle aged nausea and vomiting obstruction operating room plant leaf surgery LA - English M3 - Conference Abstract N1 - L632154819 2020-07-29 PY - 2019 SN - 1432-2307 SP - S191 ST - Gossypiboma in the abdominal cavity and its clinical implications: An autopsy report T2 - Virchows Archiv TI - Gossypiboma in the abdominal cavity and its clinical implications: An autopsy report UR - https://www.embase.com/search/results?subaction=viewrecord&id=L632154819&from=export http://dx.doi.org/10.1007/s00428-019-02631-8 VL - 475 ID - 328 ER - TY - JOUR AB - A 39-year-old woman was referred for removal of cosmetic breast implants and related siliconoma. After an exchange of breast implants at a private clinic a year previously, she had asymmetry of the right breast, persistent pain, and a generally unacceptable cosmetic result. An MRI had shown a well-defined area with spots of silicone-like material at the upper pole of the right breast. Surgical removal of presumed silicone-imbibed breast tissue was undertaken, and surprisingly a gossypiboma was found in its place, which had not been identified on the MRI. Gossypiboma is the condition of an accidentally retained surgical sponge. This complication is also known as a textiloma, gauzoma, or muslinoma and is well described in other surgical specialties. However, it is extremely rare after plastic surgery, and this case illustrates the need for continued attention to the surgical count of sponges and instruments. AD - Department of Plastic Surgery, Aalborg University Hospital, Soendre Skovvej 3, 9000 Aalborg, Denmark. AN - 23476877 AU - Lundin, K. AU - Allen, J. E. AU - Birk-Soerensen, L. C2 - PMC3586434 DO - 10.1155/2013/808624 DP - NLM ET - 2013/03/12 LA - eng N1 - 2090-6919 Lundin, Kira Allen, Julie E Birk-Soerensen, Lene Journal Article Case Rep Surg. 2013;2013:808624. doi: 10.1155/2013/808624. Epub 2013 Feb 14. PY - 2013 SN - 2090-6900 (Print) SP - 808624 ST - Gossypiboma after breast augmentation T2 - Case Rep Surg TI - Gossypiboma after breast augmentation VL - 2013 ID - 135 ER - TY - JOUR AB - Retention of surgical items is a preventable complication. The foreign body may be symptomless or migrate in and around the abdomen causing fistula formation, bowel obstruction and perforation. Some major causes responsible for this complication are emergency, prolonged, difficult surgeries associated with obesity, poor communication with an error in sponge and instrument counting. Frequency being 1/1000 to 1/32672 surgeries in the recent review of the literature. Definitive treatment for this condition is surgical removal either by laparotomy or laparoscopically. We report a case whose cesarean section was done in a secondary care hospital for brow presentation and later referred to us after two months with complaints of pain and swelling in the abdomen. Entrapment of a surgical sponge in the preperitoneal space of the abdomen was noted and later removed surgically. This case highlights the need for all health care professionals to be vigilant and cautious intraoperatively as any lapse in mop and instrument counting may be disastrous for both the patient as well as the healthcare team. There is a growing need for patient safety hospital initiation to avoid such errors by surgical teams. The aim of presenting and reporting this case is to increase awareness among healthcare workers to avoid such lapses causing great medical morbidity with medicolegal complications. AD - H. Dhar, Department of Obstetrics and Gynecology, Nizwa Hospital, Nizwa, Oman AU - Dhar, H. AU - Sashidharan, P. AU - Razek, Y. A. DB - Embase DO - 10.5005/jp-journals-10006-1655 IS - 1 KW - surgical sponge abdominal abscess abdominal pain abdominal radiography abdominal viscera abdominal wall adenofibroma anemia article case report cesarean section cholelithiasis clinical article echography Escherichia coli female foreign body gossypiboma hepatomegaly human inflammation laparotomy palpation patient history of cystectomy rectus abdominis muscle retained instrument secondary care center surgical wound x-ray computed tomography LA - English M3 - Article N1 - L2002327131 2019-08-14 2019-08-29 PY - 2019 SN - 0975-1920 0974-8938 SP - 77-80 ST - Gossypiboma (Textiloma) in the Abdominal Preperitoneal Space Following Cesarean Section: A Case Report with Literature Review T2 - Journal of SAFOG TI - Gossypiboma (Textiloma) in the Abdominal Preperitoneal Space Following Cesarean Section: A Case Report with Literature Review UR - https://www.embase.com/search/results?subaction=viewrecord&id=L2002327131&from=export http://dx.doi.org/10.5005/jp-journals-10006-1655 VL - 11 ID - 322 ER - TY - JOUR AD - Department of Surgery, Tainan Hospital, Department of Health, Executive Yuan, Tainan, Taiwan Department of Emergency, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan AU - Liu, Y. C. AU - Huang, C. M. DB - Scopus DO - 10.1016/j.dld.2012.02.019 IS - 8 M3 - Article N1 - Export Date: 10 November 2020 PY - 2012 ST - Gossypiboma T2 - Digestive and Liver Disease TI - Gossypiboma UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84863777609&doi=10.1016%2fj.dld.2012.02.019&partnerID=40&md5=7869a449cb15dfa0d2a46d05dac74d6c VL - 44 ID - 1362 ER - TY - JOUR AU - Ignatius, J. A. AU - Hartmann, W. H. DB - Scopus DO - 10.1097/00000658-197203000-00011 IS - 3 M3 - Article N1 - Cited By :35 Export Date: 10 November 2020 PY - 1972 SP - 388-397 ST - The glove starch peritonitis syndrome T2 - Annals of surgery TI - The glove starch peritonitis syndrome UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015311463&doi=10.1097%2f00000658-197203000-00011&partnerID=40&md5=4c7d3c2e608f37404ec0d8949d4a6033 VL - 175 ID - 1787 ER - TY - JOUR AB - With the increasing globalisation, immigration and travel there are increasing opportunities for the exotic diseases to be seen in different settings. This paper highlights pulmonary diseases seen in the Indian subcontinent. It discusses briefly the clinical features and management of Tropical Pulmonary Eosinophilia, Hydatid disease of the lungs, Malarial lung pathology. In addition, the low cost medical innovations evolved to use the newer medical technologies, in an affordable fashion, in a developing countries context have been detailed. © 2006 Elsevier Ltd. All rights reserved. AD - Lady Hardinge Medical College and assoc, Kalawati Saran Children's Hospital, Bangla Sahib Marg, New Delhi, 110001, India AU - Singh, V. DB - Scopus DO - 10.1016/j.prrv.2006.04.196 IS - SUPPL. 1 KW - cystic fibrosis flexible pediatric bronchoscopy foreign bodies in the airways global medicine hydatid disease of the lungs inhalation therapy low cost medical technology malarial lung sweat chloride estimation tropical diseases tropical pulmonary eosinophilia M3 - Review N1 - Cited By :2 Export Date: 10 November 2020 PY - 2006 SP - S223-S225 ST - Global pediatric pulmonology: What is coming to the West - Out of India? T2 - Paediatric Respiratory Reviews TI - Global pediatric pulmonology: What is coming to the West - Out of India? UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33745196902&doi=10.1016%2fj.prrv.2006.04.196&partnerID=40&md5=c462386dd43c4b56c3ed30a840ebf554 VL - 7 ID - 1581 ER - TY - JOUR AD - Department of Pediatric Urology, Women and Children's Hospital of Buffalo, 219 Bryant Street, Buffalo, NY 14222, United States Department of Pathology, Women and Children's Hospital of Buffalo, 219 Bryant Street, Buffalo, NY 14222, United States State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, NY, United States AU - Broderick, K. AU - Thompson, J. H. AU - Khan, A. R. AU - Greenfield, S. P. DB - Scopus DO - 10.1016/j.jpurol.2007.11.003 IS - 4 M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2008 SP - 319-321 ST - Giant cell reaction with phagocytosis adjacent to dextranomer-hyaluronic acid (Deflux) implant: Possible reason for Deflux failure T2 - Journal of Pediatric Urology TI - Giant cell reaction with phagocytosis adjacent to dextranomer-hyaluronic acid (Deflux) implant: Possible reason for Deflux failure UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-47249126858&doi=10.1016%2fj.jpurol.2007.11.003&partnerID=40&md5=b65d5397ccb990fab805fb7c4b80f355 VL - 4 ID - 1521 ER - TY - JOUR AN - 11894354 AU - Langslow, A. DA - Dec-2000 Jan DP - NLM ET - 2002/03/16 IS - 6 KW - Australia Female Foreign Bodies/*etiology Humans Hysterectomy/*adverse effects/*nursing *Malpractice Operating Room Nursing Postoperative Complications/*etiology *Surgical Sponges LA - eng N1 - Langslow, A Case Reports Journal Article Australia Aust Nurs J. 1999 Dec-2000 Jan;7(6):42-3. PY - 1999 SN - 1320-3185 (Print) 1320-3185 SP - 42-3 ST - Getting the sponge count right T2 - Aust Nurs J TI - Getting the sponge count right VL - 7 ID - 36 ER - TY - JOUR AB - Adhesion of bacteria to biomaterials and the ability of many microorganisms to form biofilms on foreign bodies are well-established as major contributors to the pathogenesis of implant-associated infections. Treatment of bone infection remains problematic, due to the difficulty of systemically administered antibiotics to locally penetrate bone. The current research addresses this issue by focusing on the development and study of novel gentamicin-loaded bioresorbable films designed to serve as "coatings" for fracture fixation devices and prevent implant-associated infections. Poly(L-lactic acid) and poly (D,L-lactic-co-glycolic acid) films containing gentamicin were developed through solution processing. The effects of polymer type, drug content, and processing conditions on the drug release profile were studied with respect to film morphology. The examined films generally exhibited a burst effect followed by a moderate approximately constant rate of release. The drug contents in the surrounding medium exceeded the required minimal effective concentration. Various gentamicin concentrations that were released from the films with time exhibited efficacy against bacterial species known to be involved in orthopedic infections. The developed systems can be applied on the surface of any metallic or polymeric fracture fixation device, and may therefore comprise a significant contribution to the field of orthopedic implants. © 2007 Wiley Periodicals, Inc. AD - Department of Biomedical Engineering, Tel-Aviv University, Tel-Aviv 69978, Israel Department of Microbiology, Technion Israel Institute of Technology, Haifa 32000, Israel AU - Aviv, M. AU - Berdicevsky, I. AU - Zilberman, M. DB - Scopus DO - 10.1002/jbm.a.31184 IS - 1 KW - Bioresorbable films Controlled drug delivery Gentamicin Poly(D,L-lactic-co-glycolic acid) Poly(lactic acid) M3 - Article N1 - Cited By :86 Export Date: 10 November 2020 PY - 2007 SP - 10-19 ST - Gentamicin-loaded bioresorbable films for prevention of bacterial infections associated with orthopedic implants T2 - Journal of Biomedical Materials Research - Part A TI - Gentamicin-loaded bioresorbable films for prevention of bacterial infections associated with orthopedic implants UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-34548770128&doi=10.1002%2fjbm.a.31184&partnerID=40&md5=d27ad2a86ea7e7a7fd0381ea7202b9cc VL - 83 ID - 1553 ER - TY - JOUR AB - Background: Congenital cutaneous candidiasis (CCC) is a rare disease that results from infection from Candida spp. acquired in utero. Case report: A full-term, 3350-g male infant was delivered by cesarean section to 29-year-old healthy woman because of fetal distress. Vaginal candidiasis, diagnosed by culture, was managed with topical therapy during the first trimester of pregnancy. No history of membranes rupture before deliver was recorded. The child presented at birth with generalized erythematous maculopapular and vesicular skin lesions over the face, trunk, and extremities, including palms and soles. The scalp and mucous membranes were spared. The remainder of the physical examination was normal. His white blood cell count was 26,000/mm3 with 71% polymorphonuclear cells, 19% lymphocytes, and 6% eosinophils. Cerebral and abdominal ecography were normal. Cultures of the blood, urine, and spinal fluid were normal. Culture of vesicle exudate was positive to Candida albicans. Skin biopsy revealed intra-epidermic pustule dermatitis. Funguses within stratum corneum were showed with periodic acideSchiff stain. Topical ketoconazol was started with progressive resolution of lesions. He was discharged from the hospital on the ninth day of life without sequelae. Discussion: The CCC is though to appear by the ascension of organism from candidal vulvovaginitis during pregnancy. CCC can produce a clinical spectrum of disease ranging from a cutaneos skin eruption without systemic involvement to a severe systemic disease with a potential risk of neonatal death. Risk factors to CCC are history of maternal candidal vulvogaginitis, intrauterine foreign body, prematurity and low birth weight <1000g. Premature low birth weight infants show higher risk of systemic involvement. The most common cutaneous presentation is a generalized eruption of erythematous macules, papules, vesicles and pustules that appears within the first six days of birth. Palms and soles are usually affected. Isolated nail dystrophy has also been documented. CCC is diagnosed by the evidence of fungus structures in the skin scrapings and skin biopsy and the positive cultures from lesions. Topical fungal therapy may be used in isolated skin involvement but systemic therapy should be used if systemic disease is suspected. We present a new case of this rare entity with lesions present at birth, in which the only identifiable risk factor, maternal vaginal candidiasis, was diagnosed and treated at the first trimester. AD - P. Davila-Seijo, Dermatology Department of Complexo Hospitalario de Pontevedra, Pontevedra, Spain AU - Davila-Seijo, P. AU - Florez-Menendez, A. AU - De La Torre, C. AU - Vilas-Gonzalez, J. DB - Embase DO - 10.1016/j.jaad.2012.12.717 IS - 4 KW - ketoconazole skin defect newborn dermatology human fungus pregnancy low birth weight skin biopsy vagina candidiasis pustule systemic disease risk skin risk factor first trimester pregnancy rupture membrane case report Candida albicans skin candidiasis cerebrospinal fluid urine topical treatment blood eosinophil Candida fetus distress lymphocyte therapy infection exudate female newborn death cesarean section rare disease dermatitis polymorphonuclear cell leukocyte count vulvovaginitis boy rash organisms physical examination hospital mucosa foreign body prematurity male stain scalp stratum corneum child papule nail dystrophy systemic therapy LA - English M3 - Conference Abstract N1 - L70997775 2013-02-26 PY - 2013 SN - 0190-9622 SP - AB173 ST - Generalized vesicular skin lesions presented at birth in a newborn T2 - Journal of the American Academy of Dermatology TI - Generalized vesicular skin lesions presented at birth in a newborn UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70997775&from=export http://dx.doi.org/10.1016/j.jaad.2012.12.717 VL - 68 ID - 484 ER - TY - JOUR AB - Bezoars (BZ) are the most common foreign bodies of gastrointestinal tract. Clinical manifestations vary depending on the location and dimension of BZ from no symptoms to acute abdominal syndrome. Hereby we report the case of gastric bezoar which was perforating through first part of duodenum into common hepatic duct. There are no certain data about the therapy of choice of bezoars. The ultimate goal of the treatment of BZs is their removal and prevention of recurrence. Here gastrostomy was done and BZ was removed in piece meal. AD - Dept of Surgery, JNMC, Sawangi (M), Wardha, India AU - Akhtar, J. M. AU - Nerker, E. N. AU - Reddy, S. P. AU - Tiwari, S. AU - Chauhan, M. K. AU - Shahapurkar, V. V. DB - Scopus IS - 1 KW - Common hepatic duct Fistula Phytobezoar M3 - Article N1 - Export Date: 10 November 2020 PY - 2011 SP - 30-33 ST - Gastro-duodenal phytobezoar causing choleducho-duodenal fistula-A rare case T2 - Pravara Medical Review TI - Gastro-duodenal phytobezoar causing choleducho-duodenal fistula-A rare case UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79956308746&partnerID=40&md5=5570a33169e38ba249c138853f8c5495 VL - 6 ID - 1426 ER - TY - JOUR AB - The majority of accidentally ingested foreign bodies is excreted from the gastrointestinal (GI) tract without any complications. Sometimes sharp foreign bodies - like chicken and fish bones - can lead to intestinal perforation and may present insidiously with a wide range of symptoms and, consequently, different diagnoses. We report the case of a 59-year-old woman presenting with fever and a 1-month history of vague abdominal pain. Computed tomography (CT) showed the presence of a hyperdense linear image close to the gastric antrum surrounded by a fluid collection and free peritoneal air. At laparotomy, a 4-cm rabbit bone fragment covered in inflamed tissue was detected next to a gastric wall perforation. Rabbit bone fragment ingestion, even if rarely reported, should not be underestimated as a possible cause of GI tract perforation. © 2016 The Author(s). Published by S. Karger AG, Basel. AD - Department of Surgical and Biomedical Sciences, Division of Radiology 2, Perugia University, Santa Maria della Misericordia Hospital, Perugia, Italy Department of Surgical and Biomedical Sciences, Division of Radiology 1, Santa Maria della Misericordia Hospital, Perugia, Italy AU - Gambaracci, G. AU - Mecarini, E. AU - Franceschini, M. S. AU - Scialpi, M. DB - Scopus DO - 10.1159/000444519 IS - 1 KW - Bone fragment Foreign body Ingestion Perforation Rabbit Stomach M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2016 SP - 121-126 ST - Gastric Perforation by Ingested Rabbit Bone Fragment T2 - Case Reports in Gastroenterology TI - Gastric Perforation by Ingested Rabbit Bone Fragment UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84973867521&doi=10.1159%2f000444519&partnerID=40&md5=e51db682cbc4b2e520ac8dee59dbd4df VL - 10 ID - 1203 ER - TY - JOUR AB - INTRODUCTION Foreign body ingestion rarely causes complications, though it can pose a significant diagnostic challenge. Perforation, particularly of more muscular viscera, can present insidiously with a wide range of differential diagnoses. PRESENTATION OF CASE Here we present a case of 75 year-old woman presenting with chest and epigastric pain. Initial imaging suggested a pancreatic lesion. Despite appropriate treatment she deteriorated clinically, and following urgent laparotomy a duck bone fragment was found to have perforated the lesser curvature of the stomach and embedded within the liver causing subhepatic abscess formation and associated inflammation. DISCUSSION There are a number of examples of insidious presentations of gastrointestinal perforation. However, we have found only one other case of a perforation presenting as a pancreatic pseudotumour, and ours is the first to have been successfully managed by removal of the foreign body and drainage of the abscess alone. CONCLUSION A high level of suspicion is required to make the correct diagnosis in cases such as these where the symptoms are not clear-cut. Thorough review and discussion of imaging prior to surgical treatment is essential to prevent unnecessary intervention. © 2014 The Authors. AD - Department of Surgery, Northwick Park Hospital, Watford Road, Harrow HA1 3UJ, United Kingdom AU - Williams, H. E. AU - Khokhar, A. A. AU - Rizvi, M. AU - Gould, S. DB - Scopus DO - 10.1016/j.ijscr.2014.04.021 IS - 7 KW - Foreign body Perforation M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2014 SP - 437-439 ST - Gastric perforation by a foreign body presenting as a pancreatic pseudotumour T2 - International Journal of Surgery Case Reports TI - Gastric perforation by a foreign body presenting as a pancreatic pseudotumour UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84902507979&doi=10.1016%2fj.ijscr.2014.04.021&partnerID=40&md5=7a28f8fcf9647df68dc94a918d3b70de VL - 5 ID - 1281 ER - TY - JOUR AD - Queens Medical Centre, Nottingham, United Kingdom Kettering General Hospital, Kettering, United Kingdom AU - Ribakovs, A. AU - Uzoigwe, C. DB - Scopus IS - 6 M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2011 SP - E103-E104 ST - From cylindrical battery ingestion to right hemicolectomy T2 - American Surgeon TI - From cylindrical battery ingestion to right hemicolectomy UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79958106016&partnerID=40&md5=3c39d5ea93f60d2514e0dee3f227b96b VL - 77 ID - 1417 ER - TY - JOUR AB - OBJECTIVE: To prospectively evaluate and accurately describe the rate and type of discrepancies encountered in the surgical count. INTRODUCTION: Despite near-universal implementation of manual counting protocols for surgical instruments and sponges, incidents of retained sponges and instruments (RSI) persist. Retrospective analyses have shown that RSI are rare and most often involve final counts erroneously thought to be correct, leading some surgeons to question the value of counting. Crucial data regarding how often the surgical count successfully detects meaningful problems before the patient leaves the operating room is lacking. METHODS: Trained physician-observers documented prospective field observations during 148 elective general surgery operations using standardized intake forms. Data collection focused on the performance of the counting protocols, and the frequency and outcomes of discrepancies (instances in which a subsequent count does not agree with the previous count). RESULTS: A mean of 16.6 counting episodes occurred per case, occupying 8.6 minutes per case. A total of 29 discrepancies involving sponges (45%), instruments (34%) or needles (21%) were observed among 19 (12.8%) operations. Most discrepancies indicated a misplaced item (59%) as opposed to a miscount (3%) or error in documentation (38%). Each discrepancy took on average 13 minutes to resolve. Counting activities after personnel changes were significantly more likely to involve a discrepancy than those for which the original team was present. CONCLUSIONS: One in 8 surgical cases involves an intraoperative discrepancy in the count. The majority of these discrepancies detect unaccounted-for sponges and instruments, which represent potential RSI. Thus, despite the recognized limitations of manual surgical counts, discrepancies should always prompt a thorough search and reconciliation process and never be ignored. AD - Center for Surgery and Public Health, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA. ccgreenberg@partners.org AN - 18650646 AU - Greenberg, C. C. AU - Regenbogen, S. E. AU - Lipsitz, S. R. AU - Diaz-Flores, R. AU - Gawande, A. A. DA - Aug DO - 10.1097/SLA.0b013e318181c9a3 DP - NLM ET - 2008/07/25 IS - 2 KW - Adult Evaluation Studies as Topic Female Foreign Bodies/*prevention & control Humans Intraoperative Care/methods Male Medical Errors/prevention & control Middle Aged Operating Rooms Postoperative Complications/prevention & control Prospective Studies Risk Assessment *Safety Management Sensitivity and Specificity Surgical Instruments/adverse effects/*statistics & numerical data Surgical Procedures, Operative/*adverse effects/methods Surgical Sponges/adverse effects/*statistics & numerical data LA - eng N1 - 1528-1140 Greenberg, Caprice C Regenbogen, Scott E Lipsitz, Stuart R Diaz-Flores, Rafael Gawande, Atul A Journal Article Research Support, Non-U.S. Gov't United States Ann Surg. 2008 Aug;248(2):337-41. doi: 10.1097/SLA.0b013e318181c9a3. PY - 2008 SN - 0003-4932 SP - 337-41 ST - The frequency and significance of discrepancies in the surgical count T2 - Ann Surg TI - The frequency and significance of discrepancies in the surgical count VL - 248 ID - 79 ER - TY - JOUR AB - The Kirschner wire (K-wire) is used in the treatment of hip fractures, and migration of a K-wire into the pelvis with resultant colon injury is a very rare complication. We report a case in which a forgotten K-wire passing across the sigmoid colon was accidentally found by screening colonoscopy in a patient with no abdominal symptoms. Surgery was performed to remove the K-wire. Although the migration of a K-wire is extremely rare, it is important for it to be considered in patients with a history of orthopedic surgery. © 2017, Japanese Society of Gastroenterology. AD - Division of Gastroenterology, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 7100011, Japan AU - Matsumoto, H. AU - Yo, S. AU - Fukushima, S. AU - Osawa, M. AU - Murao, T. AU - Ishii, M. AU - Fujita, M. AU - Shiotani, A. DB - Scopus DO - 10.1007/s12328-017-0713-8 IS - 2 KW - Colon Foreign body ingestion Kirschner wire M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2017 SP - 154-156 ST - Forgotten Kirschner wire passing across the sigmoid colon T2 - Clinical Journal of Gastroenterology TI - Forgotten Kirschner wire passing across the sigmoid colon UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85009868993&doi=10.1007%2fs12328-017-0713-8&partnerID=40&md5=93733b2975cd2b8ac458b72d40311d5a VL - 10 ID - 1138 ER - TY - JOUR AB - We report the case of a 44-year-old man presenting with abdominal pain and leukocytosis. His initial computed tomography demonstrated a pancreatic head mass concerning for pancreatic adenocarcinoma. However, on further review of the patient's imaging, the mass was determined to be an abscess caused by foreign body ingestion and gastric perforation rather than cancer. This report describes the clinical and radiographic distinctions between pancreatic neoplasia and abscess. It also reviews the pertinent medical literature on how such viscus perforations affect subsequent prognostication and clinical management. © Society of General Internal Medicine 2012. AD - Division of General Internal Medicine, New York University, Langone Medical Center, 462 First Avenue, New York, NY 10016, United States Department of Radiology, Sentara Northern Virginia Medical Center, Woodbridge, VA, United States Division of Cardiology, New York University, Langone Medical Center, New York, NY, United States AU - Garment, A. R. AU - Schwartz, M. B. AU - Axsom, K. M. DB - Scopus DO - 10.1007/s11606-012-2064-y IS - 11 KW - Abscess Foreign body Pancreatic cancer Pancreatic neoplasia M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2012 SP - 1561-1564 ST - Foreign body-induced abscess resembling pancreatic neoplasia T2 - Journal of General Internal Medicine TI - Foreign body-induced abscess resembling pancreatic neoplasia UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84867843418&doi=10.1007%2fs11606-012-2064-y&partnerID=40&md5=8c37525e23f665b4318258f77ed6693d VL - 27 ID - 1353 ER - TY - JOUR AB - Double 15 x 22 mm plastic films (2 films on top of each other) were implanted subcutaneously in CBA/H T6 mice. After 7.5, 8.5 and 9.5 mth the films were removed. Each interior film (next to the abdominal wall), covered by a cell monolayer on one side only, was cut in 4 7 x 10 mm segments. Wiping to 5 x 7, 4 x 4, 3 x 3, or 2 x 2 mm reduced the cell areas on 3 of them. They were then transferred to (CBA/H x CBA/Br)F1 or (CBA/H T6 x CBA/Br)F1 recipient mice. Tumors arising from transferred film segments were analyzed as to chromosome number and morphology, sarcoma type, degree of anaplasticity, and posttransfer latency. These criteria were used to determine whether tumors originated from the same or different clones. From this information it was estimated that preneoplastic clones were present in limited numbers and that they were either widely disseminated or spatially restricted on the implant surfaces. The extent of clone dissemination was related to preneoplastic progression. AD - Cast West. Reserve Univ., Rainbown Babies Child. Hosp., Univ. Hosp., Cleveland, Ohio 44106, United States AU - Thomassen, M. J. AU - Bouen, L. C. AU - Brand, K. G. DB - Scopus DO - 10.1093/jnci/54.1.203 IS - 1 M3 - Article N1 - Cited By :10 Export Date: 10 November 2020 PY - 1975 SP - 203-207 ST - Foreign body tumorigenesis: number, distribution, and cell density of preneoplastic clones T2 - Journal of the National Cancer Institute TI - Foreign body tumorigenesis: number, distribution, and cell density of preneoplastic clones UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0016632747&doi=10.1093%2fjnci%2f54.1.203&partnerID=40&md5=f53f7b3b023efcb63e0a64b2afd281e1 VL - 54 ID - 1773 ER - TY - JOUR AB - Implantation of synthetic matrices and biomedical devices in diabetic individuals has become a common procedure to repair and/or replace biological tissues. However, an adverse foreign body reaction that invariably occurs adjacent to implant devices impairing their function is poorly characterized in the diabetic environment. We investigated the influence of this condition on the abnormal tissue healing response in implants placed subcutaneously in normoglycemic and streptozotocin-induced diabetes in rats. In polyether-polyurethane sponge discs removed 10 days after implantation, the components of the fibrovascular tissue (angiogenesis, inflammation, fibrogenesis, and apoptosis) were assessed. Intraimplant levels of hemoglobin and vascular endothelial growth factor were not different after diabetes when compared with normoglycemic counterparts. However, there were a lower number of vessels in the fibrovascular tissue from diabetic rats when compared with vessel numbers in implants from non-diabetic animals. Overall, the inflammatory parameters (neutrophil accumulation - myeloperoxidase activity, tumor necrosis factor alpha, and monocyte chemotactic protein-1 llevels and mast cell counting) increased in subcutaneous implants after diabetes induction. However, macrophage activation (N-acetyl-β-D-glucosaminidase activity) was lower in implants from diabetic rats when compared with those from normoglycemic animals. All fibrogenic markers (transforming growth factor beta 1 levels, collagen deposition, fibrous capsule thickness, and foreign body giant cells) decreased after diabetes, whereas apoptosis (TUNEL) increased. Our results showing that hyperglycemia down regulates the main features of the foreign body reaction induced by subcutaneous implants in rats may be relevant in understanding biomaterial integration and performance in diabetes. ©2014 Socarrás et al. AD - Department of General Pathology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil Department of Livestock Sciences, University of Córdoba, Montería-Córdoba, Colombia Department of Physiology and Biophysics, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil AU - Oviedo Socarrás, T. AU - Vasconcelos, A. C. AU - Campos, P. P. AU - Pereira, N. B. AU - Souza, J. P. C. AU - Andrade, S. P. C7 - e110945 DB - Scopus DO - 10.1371/journal.pone.0110945 IS - 11 M3 - Article N1 - Cited By :27 Export Date: 10 November 2020 PY - 2014 ST - Foreign body response to subcutaneous implants in diabetic rats T2 - PLoS ONE TI - Foreign body response to subcutaneous implants in diabetic rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84910010957&doi=10.1371%2fjournal.pone.0110945&partnerID=40&md5=d90e62b4304aee060e250220312cc918 VL - 9 ID - 1255 ER - TY - JOUR AB - Objective: To compare the foreign body reaction of the monofilament polypropylene (ProleneR) mesh, and the multifilament SurgiproR mesh. Both types of mesh are widely used in laparoscopic inguinal hernia repair. Design: Prospective experimental study. Setting: University hospital, The Netherlands. Material: Six female Yorkshire & Dutch landway pigs. Intervention: Laparoscopic transabdominal implantation of six SurgiproR meshes and six ProleneR meshes in 12 inguinal sites. Main outcome measures: At 3, 6, and 12 weeks after implantation the foreign body reaction was measured by counting multinucleated giant cells at the mesh-tissue interface. Results: At all times the numbers of multinucleated giant cells at the mesh tissue interface were significantly larger with SurgiproR than with ProleneR (p < 0.001). Conclusions: There is significantly more foreign body reaction after implantation of SurgiproR than ProleneR mesh. AD - Departments of Surgery, University Hospital Maastricht, Maastricht, Netherlands St. Antoniusziekenhuis, Nieuwegein, Netherlands Department of Anatomy and Embryology, University of Limburg, Maastricht, Netherlands Department of Surgery, University Hospital Maastricht, P.O. Box 5800, NL-6202 AZ Maastricht, Netherlands AU - Beets, G. L. AU - Go, P. M. N. Y. H. AU - Van Mameren, H. DB - Scopus IS - 10 KW - Foreign body reaction Inguinal hernia repair Laparoscopy Polypropylene mesh Suture materials M3 - Article N1 - Cited By :52 Export Date: 10 November 2020 PY - 1996 SP - 823-825 ST - Foreign Body Reactions to Monofilament and Braided Polypropylene Mesh Used as Preperitoneal Implants in Pigs T2 - European Journal of Surgery TI - Foreign Body Reactions to Monofilament and Braided Polypropylene Mesh Used as Preperitoneal Implants in Pigs UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029854144&partnerID=40&md5=3b20d81a8c0ec19a53e09280fb0dfe9d VL - 162 ID - 1712 ER - TY - JOUR AB - Background: Implantable biosensors for continuous glucose monitoring can greatly improve diabetes management. However, their applications are still associated with some challenges and one of these is the gradual functionality loss postimplantation as a consequence of the foreign body response (FBR). Sensor miniaturization in combination with drug-eluting biocompatible coatings is a promising strategy to enhance in vivo performance. However, limited study has been performed to understand the effect of initial trauma and implant size on foreign body reaction as well as in vivo performance of implantable glucose sensors. Methods: Different initial trauma was induced by implanting composite coated dummy sensors into rats using various sized needles and 3 different-sized dummy sensors were implanted to examine the size effect. Histological evaluation was performed to relate the inflammatory cell counts and foreign body capsule thickness with the implantation needle size and sensor size respectively. The effect of biocompatible coating on the performance of implantable glucose sensors was determined using both coated amperometric glucose sensors and microdialysis probes. Results: The results revealed that the degree of acute inflammation was mainly controlled by the extent of the initial trauma: the greater the trauma, the greater the acute inflammatory response. Implant size did not affect the acute inflammatory phase. However, the extent of chronic inflammation and fibrous encapsulation were affected by sensor size: the smaller the size the less the extent of chronic inflammation and fibrous encapsulation. Glucose sensors implanted using 14 gauge needles showed significantly lower initial in vivo response compared to those implanted using 16 gauge needles. This was not observed for sensors with dexamethasone-eluting biocompatible coatings since inflammation was suppressed. Conclusions: The results of the current study indicate that the extent of the inflammatory response post-sensor implantation varies as a function of the initial tissue trauma as well as the sensor size. Accordingly, miniaturization of implantable biosensors together with the utilization of a drug-eluting biocompatible composite coating may be a promising strategy to achieve longterm reliable continuous glucose monitoring. © 2015 Diabetes Technology Society. AD - Department of Pharmaceutical Sciences, University of Connecticut, 69 N Eagleville Rd U3092, Storrs, CT 06269, United States Biorasis Inc., Storrs, CT, United States Institute of Materials Science, University of Connecticut, Storrs, CT, United States AU - Wang, Y. AU - Vaddiraju, S. AU - Gu, B. AU - Papadimitrakopoulos, F. AU - Burgess, D. J. DB - Scopus DO - 10.1177/1932296815601869 IS - 5 KW - Composite coatings Foreign body response Implantable glucose biosensors M3 - Article N1 - Cited By :34 Export Date: 10 November 2020 PY - 2015 SP - 966-977 ST - Foreign body reaction to implantable biosensors: Effects of tissue trauma and implant size T2 - Journal of Diabetes Science and Technology TI - Foreign body reaction to implantable biosensors: Effects of tissue trauma and implant size UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85015416397&doi=10.1177%2f1932296815601869&partnerID=40&md5=dac2023148bc7e5d78be71e3dd3e85c0 VL - 9 ID - 1241 ER - TY - JOUR AB - Foreign body reaction is a tissue response against implanted materials. We described for the first time the eosinophilic peritonitis and foreign body giant cell reaction to dialysis catheter in a nonatopic child on continuous ambulatory peritoneal dialysis. We found tenderness, redness, and swelling without purulent discharge around the peritoneal catheter; increased eosinophil count in cloudy dialysis fluid; and blood and hyperechoic granulomatous formation appearance surrounding the peritoneal catheter on ultrasonography and foreign body giant cell reaction to dialysis catheter in pathologic examination of granulomatous lesionin in our patient. The peritoneal dialysis catheter was removed due to resistance to antibiotic and antihistamine treatments for suspected peritonitis and tunnel infection. Foreign body reaction and eosinophilic peritonitis with eosinophilic cloudy dialysis effluent can exist simultaneously. Foreign body reaction should be considered in the differential diagnosis of exit site and/or tunnel infection. Ultrasonography helps distinguish between foreign body reaction and exit-site or tunnel infection. AD - Department of Pediatric Nephrology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey AN - 124600738. Language: English. Entry Date: 20180504. Revision Date: 20190708. Publication Type: journal article AU - Cetin, Nuran AU - Sav, Nadide Melike AU - Ciftci, Evrim AU - Yildiz, Bilal DB - ccm DP - EBSCOhost IS - 4 KW - Peritoneal Dialysis, Continuous Ambulatory -- Equipment and Supplies Body Fluids -- Immunology Granuloma -- Etiology Peritonitis -- Etiology Catheters -- Adverse Effects Eosinophilia -- Etiology Foreign-Body Reaction -- Etiology Peritoneal Dialysis, Continuous Ambulatory -- Adverse Effects Polycystic Kidney, Autosomal Dominant -- Therapy Peritonitis -- Diagnosis Foreign-Body Reaction -- Diagnosis Adolescence Granuloma -- Therapy Granuloma -- Immunology Treatment Outcomes Eosinophilia -- Diagnosis Male Peritonitis -- Therapy Foreign-Body Reaction -- Immunology Biopsy Foreign-Body Reaction -- Therapy Granuloma -- Diagnosis Polycystic Kidney, Autosomal Dominant -- Diagnosis Peritonitis -- Immunology Eosinophilia -- Immunology Device Removal Eosinophilia -- Therapy N1 - case study. Journal Subset: Biomedical; Double Blind Peer Reviewed; Middle East; Peer Reviewed. NLM UID: 101316967. PMID: NLM28794295. PY - 2017 SN - 1735-8582 SP - 319-321 ST - Foreign Body Reaction to Dialysis Chatheter and Peritoneal Fluid Eosinophilia in a Child on Continuous Ambulatory Peritoneal Dialysis T2 - Iranian Journal of Kidney Diseases TI - Foreign Body Reaction to Dialysis Chatheter and Peritoneal Fluid Eosinophilia in a Child on Continuous Ambulatory Peritoneal Dialysis UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=124600738&site=ehost-live&scope=site VL - 11 ID - 762 ER - TY - JOUR AB - The device for intervertebral assisted motion (DIAM) is a dynamic implant that consists of a silicone bumper enveloped by a polyethylene terephthalate (PET) fiber sack. Silicone and PET were used because of their biological inertness, but repetitive motion of the spine can cause wear on the implant nonetheless. The purpose of this study is to report a case of foreign body reaction (FBR) against a DIAM. A 72-year-old female patient presented with lower back pain and both legs radiating pain. She had undergone DIAM implantation at L4–5 for spinal stenosis 5 years previously. The intervertebral disc space of L4–5, where the DIAM was inserted, had collapsed and degenerative scoliosis had developed due to left-side collapse. MRI showed L3–4 thecal sac compression and left L4–5 foraminal stenosis. The patient underwent removal of the DIAM and instrumented fusion from L3 to L5. During surgery, fluid and granulation tissue were evident around the DIAM. Histopathology showed scattered wear debris from the DIAM causing chronic inflammation due to the resulting FBR. A FBR due to wear debris of a DIAM can induce a hypersensitivity reaction and bone resorption around the implant, causing it to loosen. © 2016 The Korean Neurosurgical Society. AD - Department of Orthopaedic Surgery, Jeju National University Hospital, School of Medicine, Jeju National UniversityJeju, South Korea Department of Orthopaedic Surgery, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea AU - Seo, J. Y. AU - Ha, K. Y. AU - Kim, Y. H. AU - Ahn, J. H. DB - Scopus DO - 10.3340/jkns.2016.59.6.647 IS - 6 KW - Device for intervertebral assisted motion Foreign body reaction Polyethylene terephthalate Silicone M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2016 SP - 647-649 ST - Foreign body reaction after implantation of a device for intervertebral assisted motion T2 - Journal of Korean Neurosurgical Society TI - Foreign body reaction after implantation of a device for intervertebral assisted motion UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84994389269&doi=10.3340%2fjkns.2016.59.6.647&partnerID=40&md5=6a2de117fa3c7aa2aa9344b935814afa VL - 59 ID - 1202 ER - TY - JOUR AB - A 29-year-old man presented to his local orthopaedic service with a mass in the medial aspect of his left thigh, present for 1 year. It had not changed in size, although he complained of increasing tightness in the region. He denied any systemic symptoms or history of local trauma. Extensive imaging performed at his local hospital was thought suggestive of a musculoskeletal tumour. The patient was referred to our tertiary centre musculoskeletal tumour clinic. Review of external imaging and further investigations revealed a fluid-filled intramuscular mass containing an echogenic focus consistent with foreign body. Ultrasound-guided aspiration yielded fluid which grew Staphylococcus aureus. Only when presented with this information did the patient vaguely recall sitting on a wooden kebab stick 30 months previously. At surgery, a thick-walled abscess with a central foreign body was identified and drained. At follow-up 1 month later, he was well with no recurrent problems. AD - Department of Trauma and Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom Department of Trauma and Orthopaedics, NHS Lothian, Edinburgh, United Kingdom AU - Maempel, J. F. AU - Nicol, G. AU - Clement, R. G. E. AU - Porter, D. C7 - 007473 DB - Scopus DO - 10.1136/bcr-2012-007473 M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2013 ST - A foreign body masquerading as a tumour T2 - BMJ Case Reports TI - A foreign body masquerading as a tumour UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84874496022&doi=10.1136%2fbcr-2012-007473&partnerID=40&md5=77d56e33919385f701dae66dd237727b ID - 1326 ER - TY - JOUR AB - Background Foreign body aspiration usually presents with cough which is of sudden onset, respiratory distress and wheeze. Complications such as recurrent pneumonia, bronchiectasis, and rarely empyema and atelectasis occur when the foreign body has been retained in the lungs for a long period of time. This case highlights the complications of the delayed diagnosis of retained foreign body in the bronchus. Methods The case record file of the index case was retrieved from the hospital records. Information extracted from the records included: age, sex, date of presentation, symptoms and signs at presentation and on subsequent review, final diagnosis, investigations and treatment, and outcome of treatment. Case Report AC is a 15-year-old adolescent female who developed right atelectasis and loculated empyema secondary to a foreign body aspirated 3yrs earlier. The foreign body (an office pin) was lodged in the right main bronchus. She presented to a nearby clinic but referral to a tertiary center for appropriate treatment was delayed. She had repeated chest infections. Symptoms were recurrent episodes of cough, fast breathing and hemoptysis over a period of 3 years for which she took over the- counter (OTC) medications. She presented to our facility when the symptoms progressively worsened. Findings on examination were tachypnea, splinting of the chest to the right, deviation of the trachea to the left, dull percussion note, reduced breath sounds, and crepitations on the right hemithorax. Oxygen saturation in roomair (SPO2) was 93%. Apex beat was displaced. Chest X-ray (CXR) and chest ultrasonography showed features in keeping with right lung collapse with right sided pleural effusion. Computerized tomography scan was not performed owing to financial constraints. Pleural fluid microscopy yielded pus cells while culture yielded no bacterial growth. Complete blood count showed leucocytosis with predominant granulocytosis, anemia, and reactive thrombocytosis (platelet count >1000000/mm3). The Erythrocyte Sedimentation Rate (ESR) was 130mm/hr. Screening for tuberculosis and retroviraldisease was negative. She receivedi ntravenous Ceftriazone and Vancomycin. Following some degree of resolution of the opacities in the CXR, the pin was located in the right main bronchus. The patient was referred to the cardiothoracic surgeons for furthermanagement. A chest tube was inserted which drained minimally. She underwent a decortication for the loculated empyema. An attempt to search for and retrieve the foreign body through a right main bronchotomy was unsuccessful. She is scheduled for bronchoscopy in order to remove the foreign body. Conclusions This case highlights the need for early diagnosis and prompt removal of aspirated foreign body in order to avert the long term complications such as empyema, atelectasis and bronchiectasis which invariably reduces the individual's quality of life. AD - J.N. Eze, Department of Paediatrics, University of Nigeria Teaching Hospital Ituku Ozalla, Enugu, Nigeria AU - Eze, J. N. AU - Ayuk, A. C. AU - Okoh, O. K. AU - Oguonu, T. DB - Embase DO - 10.1002/ppul.23731 KW - non prescription drug vancomycin abnormal respiratory sound adolescent anemia atelectasis bacterial growth bronchiectasis bronchoscopy case report chest infection chest tube computer assisted tomography coughing crackle decortication diagnosis early diagnosis echography empyema erythrocyte sedimentation rate female foreign body aspiration granulocytosis hemoptysis human main bronchus medical record microscopy oxygen saturation patient referral percussion pleura effusion pleura fluid pus quality of life right lung screening splinting symptom tachypnea thoracic surgeon thorax radiography platelet count thrombocytosis trachea tuberculosis LA - English M3 - Conference Abstract N1 - L617069591 2017-07-06 PY - 2017 SN - 1099-0496 SP - S114 ST - Foreign body induced empyema in an adolescent: Challenges of management in a resource-poor setting T2 - Pediatric Pulmonology TI - Foreign body induced empyema in an adolescent: Challenges of management in a resource-poor setting UR - https://www.embase.com/search/results?subaction=viewrecord&id=L617069591&from=export http://dx.doi.org/10.1002/ppul.23731 VL - 52 ID - 376 ER - TY - JOUR AB - The case reported presented as an acute phase of chronic' respiratory symptoms with high leukocyte count and no history suggesting the presence of a foreign body. Investigation revealed a safety pin lodged at a very unusual site in the substance of the tongue and a large retropharyngeal abscess. Evidence suggested that the pin had been present there for 2 yr. Technical difficulties faced in localizing and removing the foreign body at operation are described. The authors have not found a reference of a foreign body lodged at this site. AD - A.A. Khan, Dept. of ENT Dis., Dacca Med. Coll., Dacca AU - Khan, A. A. AU - Huq, M. DB - Embase Classic Medline IS - 2 KW - foreign body leukocyte count retropharyngeal abscess safety tongue LA - English M3 - Article N1 - L288126908 1968-12-01 PY - 1968 SP - 153-156 ST - Foreign body in the genio-glossus T2 - Journal of Laryngology TI - Foreign body in the genio-glossus UR - https://www.embase.com/search/results?subaction=viewrecord&id=L288126908&from=export VL - 82 ID - 692 ER - TY - JOUR AB - The osteopetrosis (op) mutation in mice is characterized by generalized skeletal sclerosis; reduced numbers of osteoclasts, macrophages, and monocytes; and failure to be cured by bone marrow transplantation. This mutation has been shown to result from an absence of colony-stimulating factor-1 (CSF-1) and reported to be cured by treatment with CSF-1. Macrophage polykaryons are known to be formed by fusion of mononuclear precursors and the presence of subcutaneous implants can elicit the formation of macrophage polykaryons. In order to determine if recruitment of foreign body giant cells is also impaired in osteopetrotic mice, tissue reactions to subcutaneously implanted polyvinyl sponges were studied and compared with normal mice. Our result showed that, in the op mouse, recruitment of macrophages and foreign body giant cells in response to the implants was quantitatively not different from that of normal mice. However, these cells were smaller and did not migrate as deeply into the implant as those seen in normal littermates. In contrast, resident macrophages obtained by peritoneal lavage were significantly reduced in op mice. These data indicate that there is a deficiency in the ability of op mice to mount a foreign body giant cell response to an implanted sponge characterized by a deficiency in the recruitment of precursor cells that are capable of either full development and spreading or migration into the implanted sponge. These data add to the emerging appreciation of the regional differences among macrophage populations in their dependence on CSF-1 for differentiation and survival. © 2002 Elsevier Science Ltd. All rights reserved. AD - Department of Oral Pathobiological Science, Hokkaido University, Graduate School of Dental Medicine, Sapporo 060-8586, Japan Department of Cell Biology, University of Massachusetts, Medical School, Worcester, MA 01655, United States Department of Oral Pathobiological Science, Hokkaido University, Graduate School of Dental Medicine, Kita 13 Nishi 7 Kita-ku, Sapporo 060-8586, Japan AU - Iizuka, T. AU - Kohgo, T. AU - Marks Jr, S. C. DB - Scopus DO - 10.1016/S0040-8166(02)00015-0 IS - 2 KW - Colony-stimulating factor-1 Foreign body giant cell Implant Mouse Osteopetrosis M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2002 SP - 103-108 ST - Foreign body giant cell induction in the CSF-1-deficient osteopetrotic (op/op) mouse T2 - Tissue and Cell TI - Foreign body giant cell induction in the CSF-1-deficient osteopetrotic (op/op) mouse UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036545283&doi=10.1016%2fS0040-8166%2802%2900015-0&partnerID=40&md5=36377a15dd892c51080dee39ae0bf2b9 VL - 34 ID - 1663 ER - TY - JOUR AB - Toothbrush ingestion is rare and most commonly seen in patients with psychiatric comorbidities and in young women with a medical history of eating disorders who try to induce emesis. Long ingested objects, such as a toothbrush, cannot pass the gastrointestinal tract spontaneously and require endoscopic removal or even a surgical approach in cases of unsuccessful endoscopic removal or complication development. We present a case of a 71-year-old male with hiatal hernia without psychiatric or neurological comorbidity who accidentally ingested a toothbrush during oral hygiene routine. After X-ray confirmation, the toothbrush was removed endoscopically. © 2017 The Author(s). Published by S. Karger AG, Basel. AD - Clinical Department for Ear Nose and Throat, Split University Hospital Center, Split, Croatia Clinical Department for Internal Medicine, Division of Gastroenterology, Split University Hospital Center, Split, Croatia AU - Klancnik, M. AU - Grgec, M. AU - Perković, N. AU - Ivanišević, P. AU - Poljak, N. K. DB - Scopus DO - 10.1159/000464277 IS - 1 KW - Endoscopy Esophageal foreign body Hiatal hernia Toothbrush M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2017 SP - 184-189 ST - A foreign body (Toothbrush) in the Esophagus of a Patient with Hiatal Hernia T2 - Case Reports in Gastroenterology TI - A foreign body (Toothbrush) in the Esophagus of a Patient with Hiatal Hernia UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018516753&doi=10.1159%2f000464277&partnerID=40&md5=f4161d8052245b4381cbd6178d785ff2 VL - 11 ID - 1149 ER - TY - JOUR AB - Introduction: Eosinophilic oesophagitis (EoE) is a chronic, immunemediated oesophageal disease characterized clinically by symptoms related to esophageal dysfunction and histologically by eosinophilpredominant inflammation.1 Incidence and prevalence of this condition is increasing.2 The presentation of EoE varies with age but dysphagia is common in adults and older children.3 We hypothesize that most children requiring endoscopic management of food bolus impaction will have EoE. Methods: Retrospective review of all patients presenting or referred with food bolus impaction to a paediatric hospital between 1st Nov 2011 and 31st Dec 2014 inclusive. ICD-10 codes for endoscopy and removal of foreign body (30478-00, 30478-10) were used to identify patients who required endoscopy. All patients with oesophageal foreign bodies were reviewed but only those with food in the oesophagus were included in the study. EoE was defined as the presence of ≥15 eosinophils/high power field on biopsy in either proximal and/or distal oesophagus.4 Results: 138 endoscopies were performed in 133 children. Oesophageal foreign bodies were noted in 78 procedures of which 76 were performed emergently. Procedures were mainly performed by gastroenterologists (n = 50) and otolaryngologists (n = 23). Common foreign bodies include coins (n = 33), food (n = 22), button battery (n = 3), dental wire (n = 3), and toys (n = 3). 22 endoscopies were performed in 19 patients for food bolus impaction, and histology available in 14/19 (74%) patients. 79% (15/19) of these patients were male and median age at presentation was 12.08 (range 0.85-15.05) years. 79% (11/14) of those biopsied fulfilled histologic criteria for EoE. Interestingly the remaining 3 patients who had biopsies all demonstrated oesophageal eosinophilia although their count (range 3-13 eos/hpf) was insufficient to be diagnostic of EoE. 2/5 patients who did not have biopsies were known to have an oesophageal stricture after previous surgery. Most children presenting with food bolus impaction therefore had underlying oesophageal pathology. Conclusions: Food bolus impaction in children is nearly always a consequence of underlying oesophageal disorder, of which EoE is the most common. We recommend that all children presenting with food bolus impaction have oesophageal biopsies for EoE. AD - T. Bradley, Dept. of Gastroenterology, Hepatology and Liver Transplant, Lady Cilento Children's Hospital, Australia AU - Bradley, T. AU - Withers, G. AU - Ee, L. DB - Embase DO - 10.1111/jgh.13097 KW - child human eosinophilic esophagitis Australian gastroenterology food patient endoscopy biopsy esophagus foreign body esophagus procedures foreign body prevalence gastroenterologist ICD-10 esophagus biopsy otolaryngologist pathology patient history of surgery esophagus stenosis pediatric hospital diagnosis eosinophilia histology male dental wire diseases electric battery adult dysphagia inflammation esophagus disease LA - English M3 - Conference Abstract N1 - L72062711 2015-11-05 PY - 2015 SN - 0815-9319 SP - 166 ST - Food bolus impaction in children is nearly always from eosinophilic oesophagitis T2 - Journal of Gastroenterology and Hepatology (Australia) TI - Food bolus impaction in children is nearly always from eosinophilic oesophagitis UR - https://www.embase.com/search/results?subaction=viewrecord&id=L72062711&from=export http://dx.doi.org/10.1111/jgh.13097 VL - 30 ID - 427 ER - TY - JOUR AB - Introduction: Eosinophilic esophagitis (EoE) is a chronic, immune-mediated esophageal disease characterized clinically by symptoms related to esophageal dysfunction and histologically by eosinophil-predominant inflammation. Incidence and prevalence of this condition is increasing. The presentation of EoE varies with age but dysphagia is common in adults and older children. We hypothesize that most children requiring endoscopic management of food bolus impaction will have EoE. Methods: Retrospective review of all patients presenting or referred with food bolus impaction to a tertiary paediatric hospital between 1st Nov 2011 and 31st Dec 2014 inclusive. ICD-10 codes for endoscopy and removal of foreign body (30478-00, 30478-10) were used to identify patients who required endoscopy. All patients with esophageal foreign bodies were reviewed but only those with food in the esophagus were included in the study. EoE was defined as the presence of ≥15 eosinophils/ high power field on biopsy in either proximal and/or distal esophagus. Results: 138 endoscopies were performed in 133 children. Esophageal foreign bodies were noted in 78 procedures of which 76 were performed emergently. Procedures were mainly performed by gastroenterologists (n=50) and otolaryngologists (n=23). Common foreign bodies include coins (n=33), food (n=22), button battery (n=3), dental wire (n=3), and toys (n=3). 22 endoscopies were performed in 19 patients for food bolus impaction, and histology available in 14/19 (74%) patients. 79% (15/19) of these patients were male and median age at presentation was 12.08 (range 0.85-15.05) years. 79% (11/14) of those biopsied fulfilled histologic criteria for EoE. Interestingly the remaining 3 patients who had biopsies all demonstrated esophageal eosinophilia although their count (range 3-13eos/hpf) was insufficient to be diagnostic of EoE. 2/5 patients who did not have biopsies were known to have an esophageal stricture after previous surgery. Most children presenting with food bolus impaction therefore had underlying esophageal pathology. Conclusions: Food bolus impaction in children is nearly always a consequence of underlying esophageal disorder, of which EoE is the most common. We recommend that all children presenting with food bolus impaction have esophageal biopsies for EoE. AD - T.C. Bradley AU - Bradley, T. C. AU - Withers, G. D. AU - Ee, L. C. DB - Embase IS - 4 KW - child human eosinophilic esophagitis gastrointestinal disease food patient endoscopy biopsy procedures esophagus esophagus foreign body foreign body inflammation eosinophil ICD-10 esophagus biopsy pediatric hospital pathology esophagus stenosis male diagnosis histology adult dysphagia prevalence dental wire electric battery otolaryngologist eosinophilia gastroenterologist patient history of surgery diseases esophagus disease LA - English M3 - Conference Abstract N1 - L72270604 2016-05-31 PY - 2016 SN - 0016-5085 SP - S437 ST - Food bolus impaction in children is nearly always from eosinophilic esophagitis T2 - Gastroenterology TI - Food bolus impaction in children is nearly always from eosinophilic esophagitis UR - https://www.embase.com/search/results?subaction=viewrecord&id=L72270604&from=export VL - 150 ID - 409 ER - TY - JOUR AD - Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, United States Department of Radiology, University of Colorado School of Medicine, Aurora, CO, United States Department of Pediatric Surgery, University of Colorado School of Medicine, Aurora, CO, United States Department of Pathology and Laboratory Medicine, University of Colorado School of Medicine, Aurora, CO, United States AU - Liptzin, D. R. AU - Fan, L. L. AU - Stillwell, P. C. AU - Dannull, K. A. AU - Fadell, M. F. AU - Partrick, D. A. AU - Dishop, M. K. DB - Scopus DO - 10.1164/rccm.201403-0533IM IS - 8 M3 - Article N1 - Export Date: 10 November 2020 PY - 2014 SP - e29 ST - Flip-flop lung. An unusual etiology of bronchiectasis T2 - American Journal of Respiratory and Critical Care Medicine TI - Flip-flop lung. An unusual etiology of bronchiectasis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84922041699&doi=10.1164%2frccm.201403-0533IM&partnerID=40&md5=39a651fc271f02af129695fd9d9c2347 VL - 190 ID - 1270 ER - TY - JOUR AB - Poly(trimethylene carbonate) (PTMC) crosslinked by gamma irradiation was evaluated as a scaffolding material for cardiac tissue engineering. The PTMC networks allowed adhesion and proliferation of neonatal mouse cardiomyocytes and preservation of their phenotype. Highly porous structures having tuneable mechanical properties were prepared. The stiffness of these structures was close to that of myocardium. Upon implantation on rat hearts, gamma irradiated porous scaffolds were found to be eroded by macrophages and foreign body giant cells. Introduction: In engineering of soft tissues such as cardiovascular tissues, the stiffness of the scaffolds is of great importance in maintaining proper function of cells and controlling the differentiation of stem cells [1,2]. Cyclic stresses are often applied to cell-seeded constructs to control cell phenotype and to enhance production of extracellular matrix [3], which also requires flexible and elastic materials. PTMC is a biocompatible and biodegradable polymer with a low elastic modulus of approximately 6 MPa that can be crosslinked into an elastomeric network by gamma irradiation under vacuum [4,5]. In this study, we assessed the suitability of PTMC networks in preparing flexible porous scaffolds for cardiac tissue engineering. Experimental methods: PTMC was synthesized by ring opening polymerization of TMC monomer [5,6]. To characterise the networks formed upon gamma irradiation, equilibrium swelling experiments were performed on compression moulded films using chloroform [6]. For cell culturing studies, PTMC spin-coated glass discs (15 mm in diameter) and non-coated glass discs (controls) were gamma irradiated at 50 kGy under vacuum. Also controls in which fibronectin (1% in gelatine solution in phosphate buffer) was used to coat the films were employed. Neonatal cardiomyocytes (CMs) isolated from one-day old mice were seeded on the materials at a density of 5×104 cells/cm2 (n=3 per time point). The number of adhering CMs was determined by counting the nuclei stained with 4',6-diamidino-2-phenylindole on eight pictures per disc at 200× magnification. To determine the percentage of proliferating cells, 5- bromo-2-deoxyuridine was added to the cell cultures one day prior to fixation. Porous PTMC scaffolds were prepared by a process involving polymer coagulation, compression moulding and particulate leaching. Salt particles previously sieved to a size range of 106-250 μm were dispersed in polymer solutions in chloroform and then precipitated into a non-solvent. Porogen-to-polymer ratios were 85:15, 90:10, and 93:7 w/w. After drying, the salt-polymer composites were compression moulded and gamma irradiated (0, 50, and 100 kGy). The salt particles were leached out using Milli-Q water at 4 °C for 3-4 days. The porosities of the scaffolds were determined by measuring their size and mass. Their pore size and pore interconnectivity were assessed by scanning electron microscopy (SEM). Tensile measurements were performed on rectangular slabs of the porous specimens (n=5, measuring approximately 100×5×1 mm) according to ASTM-D 882-91. For supra-epicardial implantations on the hearts of Albino Oxford rats, salt leaching was done with cold sterile water under sterile conditions. All scaffolds were endotoxin-free. The disk-shaped scaffolds (n=4, 10 mm in diameter and approximately 500 μm in thickness) were implanted supra-epicardially through a small incision made on the pericardium and then fixated with a Safil® suture to the left ventricle. After 5 days of implantation, the hearts with the scaffolds were explanted. Histological and immunohistochemical analyses were performed to evaluate the response to the porous PTMC scaffolds. Histological sections were stained with toluidine blue. Macrophages and T-lymphocytes were stained using ED1 and R73 antibodies, respectively and the extent of vascularisation was assessed using anti-collagen IV. Results and discussion The purified PTMC polymer had a number average molecular weight of 306 kg/mol with a polydispersity index of 1.33. Gam a irradiation led to simultaneous sterilisation and crosslinking of the PTMC films. Upon irradiation at 50 kGy, networks with gel contents of 48±1% and swelling ratios of 84±1 vol/vol were formed. At 100 kGy, the respective values were 61±1% and 43± 1 vol/vol. Initially, the adhesion and proliferation of neonatal cardiomyocytes (CMs) on gamma irradiated PTMC surfaces were evaluated. The CMs adheredwell to the PTMC networks, in a time dependent fashion. After 2, 4, and 8 h of culturing, the total numbers of CMs adhering to the PTMC networks were 528±57, 603±360, and 1314±169, respectively. The values for the non-coated glass disc controls were lower at 2 h and 4 h (299±42 and 451±335, respectively), but comparable to those of the PTMC networks at 8 h (1626±137). It should be noted that, the adhesion of CMs onto PTMC networks was comparable to the adhesion onto the fibronectin-coated PTMC networks. The values were 607±380, 887±67, and 1559±667 after 2, 4 and 8 h of culturing, respectively. The CMs had a more spread morphology on the PTMC networks than when compared to non-coated glass discs, especially on the early days of culturing (Fig. 1A and B). The CMs also proliferated very well on the networks, almost reaching confluency after 14 days of culture (Fig. 1D). Importantly, the cells beat spontaneously, suggesting that they had preserved their phenotype. The percentage of proliferating cells increased during culturing, reaching 20.9±3.3% for PTMC networks and 25.1±4.2 for the noncoated controls. Figure Presented Porous PTMC structures were prepared by a salt-leaching technique. Porous structures with high porosities ranging from 70.8±1.7 to 86.1±0.1% depending on the porogen-to-polymer ratio were obtained. SEM analysis of the porous structures revealed that the pores were interconnected and their sizes ranged from 100 to 200 μm(data not shown). Crosslinking by gamma irradiation resulted in form-stable porous structures: upon incubation in PBS at 37 °C for two days, non-irradiated porous structures shrunk by 35 to 55 vol.% depending on the porogen-to-polymer ratio, whereas no significant shrinkage was observed for the crosslinked structures. Shrinkage of scaffolds is not desired, as it would lead to lower porosities and pore sizes. The porous PTMC structures were highly flexible, with elastic moduli that could be varied from 373±60 to 84±12 kPa by adjusting the porogen-to-polymer ratio (porosity) and (to a lesser extent) by adjusting the irradiation dose (Fig. 2A). This allowed the preparation of structures with stiffness values close to those of human myocardium (20-500 kPa) [7]. The stress at break values of the porous structures also depended on porosity and the applied irradiation dose, the values ranged from 469±30 to 72±8 kPa. All materials exhibited high elongations at break ranging from 145±20 to 209± 24%. A significant dependence on porosity or irradiation dose was not observed. Figure Presented The host response to tissue engineered constructs is a key factor in determining their success [8.9]. These responses can be towards the biomaterial component and/or the implanted cells, which can also influence each other. Moreover, the biodegradation process and its rate can modulate these responses. We investigated the response to bare PTMC scaffolds (porosity of approximately 80% and irradiated at 50 kGy) which were supraepicardially implanted on the hearts of rats. After five days of implantation, macroscopically no abnormalities were observed on the explanted hearts. At the implant site large numbers of newly formed blood vessels were present, which is highly desired in tissue engineering (Fig. 3A). The density of lymphocytes at the implant sitewas not high (115±27 cells/mm2). However, already at this early time point, high numbers of macrophages and foreign body giant cells had infiltrated the scaffolds and their surroundings (Fig. 3B and C). These cells were found to have phagocytosed fragments of the scaffolds. These histological and immunohistochemical evaluations show that the PTMC sca foldswere angiogenic and had been rapidly degraded upon implantation on rat hearts. Figure Presented. Conclusion: Networks based on PTMC are useful materials for cardiac tissue engineering, as they allow the adhesion and proliferation of neonatal cardiomyocytes and can be easily processed into flexible porous scaffolds with tuneable mechanical properties. However, the erosion of these materials needs to be tuned to achieve an appropriate balance between scaffold degradation and tissue regeneration. AD - D.W. Grijpma, MIRA Institute for Biomedical Technology and Technical Medicine, Department of Polymer Chemistry and Biomaterials, University of Twente, P.O. Box 217, AE, Enschede, Netherlands AU - Bat, E. AU - Harmsen, M. C. AU - Plantinga, J. A. AU - Van Luyn, M. J. A. AU - Feijen, J. AU - Grijpma, D. W. DB - Embase DO - 10.1016/j.jconrel.2010.07.013 IS - 1 KW - cyclopropane carbonic acid polymer glass chloroform fibronectin tolonium chloride antibody collagen type 4 biomaterial monomer gelatin phosphate 4',6 diamidino 2 phenylindole broxuridine solvent water sterile water endotoxin heart drug delivery system tissue engineering porosity adhesion gamma irradiation implantation rat irradiation compression rigidity phenotype leaching macrophage density giant cell swelling Young modulus implant cell proliferation mouse cross linking tissues vacuum cardiac muscle suture heart left ventricle tissue section T lymphocyte vascularization scanning electron microscopy molecular weight instrument sterilization morphology human immune response biodegradation blood vessel lymphocyte tissue regeneration preservation engineering soft tissue stem cell extracellular matrix ring opening cell culture albinism thickness incision pericardium polymerization LA - English M3 - Conference Abstract N1 - L70387014 2011-04-19 PY - 2010 SN - 0168-3659 SP - e74-e76 ST - Flexible scaffolds based on poly(trimethylene carbonate) networks for cardiac tissue engineering T2 - Journal of Controlled Release TI - Flexible scaffolds based on poly(trimethylene carbonate) networks for cardiac tissue engineering UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70387014&from=export http://dx.doi.org/10.1016/j.jconrel.2010.07.013 VL - 148 ID - 551 ER - TY - JOUR AB - A 75 year-old female was admitted to the emergency department with complaints of abdominal cramping pain, back pain and diarrhea for one day. She also had fever, ever up to 39°. In these two weeks, she felt occasionally epigastric pain. Her past medical history included hypertension. On physical examination, she was conscious and alert. Abdominal examination revealed diffuse tenderness and knocking pain over right flank. Laboratory tests indicated an degraded white cell count of 2890/cumm with 22% band forms, C-reactive protein of 25 mg/dL and abdominal liver function tests (Alanine Aminotransferase: 149 U/L, alkaline phosphatase: 249 U/L, gammaglutamyl transferase: 175 U/L) without hyperbilirubinemia. Abdominal X-ray showed paralytic ileus. Our presumptive diagnosis was acute peritonitis, based on the patient's symptoms. Empirical antibiotics were administered immediately, and a computed tomography (CT) imaging study was performed. The CT scan showed a stick like foreign body noted between ventral side of pylorus and SMV lumen, about 1.5 cm in length and associated with perifocal infiltration and segmental SMV thrombus formation.(Fig. 1) However, there is no obvious pneumoperitoneum and no evident ascites is associated. An emergency exploratory laparotomy was performed, revealing stomach perforation at posterior wall with a 3 cm fish bone thourgh pancreas into SMV. Localized inflammation and fibrosis were identified without obvious fluid accumulation(Fig. 2-4). Removal of fish bone and simple closure of stomach perforation were performed. Blood cultures revealed Bacteroides thetaiotaomicron. Three weeks later, she received a follow-up CT scan which showed SMV obliteration with chronic pylephlebitis. AD - J.H. Kang, General Surgery, Kaohsiung Veterans General Hospital, KAOHSIUNG, Taiwan AU - Kang, J. H. AU - Chen, I. S. DB - Embase DO - 10.1007/s00464-019-07109-x IS - 2 KW - alanine aminotransferase alkaline phosphatase antibiotic agent C reactive protein endogenous compound gamma glutamyltransferase abdominal radiography aged alanine aminotransferase blood level ascites backache Bacteroides thetaiotaomicron blood clotting blood culture bone case report clinical article computer assisted tomography conference abstract diarrhea emergency ward epigastric pain female fever fibrosis fish flank follow up foreign body human hyperbilirubinemia hypertension laboratory test laparotomy leukocyte count liver function test medical history muscle cramp nonhuman pancreas paralytic ileus peritonitis physical examination pneumoperitoneum pylorus stomach perforation superior mesenteric vein thrombosis LA - English M3 - Conference Abstract N1 - L632126303 2020-07-24 PY - 2019 SN - 1432-2218 SP - S769 ST - Fish bone penetration through stomach into superior mesenteric vein causing SMV thrombosis formation: Case report T2 - Surgical Endoscopy TI - Fish bone penetration through stomach into superior mesenteric vein causing SMV thrombosis formation: Case report UR - https://www.embase.com/search/results?subaction=viewrecord&id=L632126303&from=export http://dx.doi.org/10.1007/s00464-019-07109-x VL - 33 ID - 327 ER - TY - JOUR AB - We present a case of an elderly patient who visited our emergency department owing to a pyogenic liver abscess. A linear calcified object extending from the stomach to the liver was found on images from a computed tomography scan. The patient underwent laparotomy and a retained fish bone and a hepato-duodenal fistula were discovered during surgery. The bacteriological presentation of foreign-body-related liver abscesses are unique and most of the patients require surgical interventions to remove the foreign bodies. However, it is difficult to obtain a reliable history of accidentally swallowed foreign bodies. Physicians should exam the images carefully for any clues of retained foreign bodies in patients with pyogenic liver abscess. Copyright © 2012, Taiwan Society of Geriatric Emergency & Critical Care Medicine. Published by Elsevier Taiwan LLC. All rights reserved. AD - Emergency Department, Chi-Mei Medical Center, 901 Chung-Hwa Road, Yung Kang, Tainan 710 Liouying, Taiwan Department of Biotechnology, Southern Tainan University of Technology, Liouying, Taiwan Department of Emergency Medicine, Chi-Mei Medical Center, Liouying, Taiwan Department of Emergency Medicine, Taipei Medical University, Taipei, Taiwan AU - Chen, M. H. AU - Lin, H. J. AU - Foo, N. P. AU - Chen, K. T. DB - Scopus DO - 10.1016/j.ijge.2012.05.012 IS - 1 KW - computed tomography scan foreign body geriatric liver abscess surgery M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2013 SP - 54-56 ST - Fish bone penetration of the duodenum: A rare cause of liver abscess T2 - International Journal of Gerontology TI - Fish bone penetration of the duodenum: A rare cause of liver abscess UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84875261173&doi=10.1016%2fj.ijge.2012.05.012&partnerID=40&md5=0b63908a9b34a067f9107ee10fdde300 VL - 7 ID - 1328 ER - TY - JOUR AB - Fish bones are the most common foreign objects leading to bowel perforation. Most cases are confined to the extraluminal space without penetration of an adjacent organ. However, abscess formation due to the perforation of the rectosigmoid colon by a fish bone can lead to the penetration of the urinary bladder and may subsequently cause the fish bone to migrate into the urinary bladder. In the presented case, a 42-yearold female was admitted for lower abdominal pain. The computed tomography (CT) demonstrated a 5cm pelvic abscess containing a thin and curvilinear foreign body. After conservative management, the patient was discharged. After 1 mo, the subject developed a mechanical ileus. Surgery had to be delayed due to her hyperthyroidism. Migration of the foreign body to the urinary bladder was shown on additional CT. A Yellowish fish bone 3.5 cm in size was removed through intraoperative cystoscopy. The patient was discharged 8 d after the operation without any unexpected event. © 2014 Baishideng Publishing Group Inc. All rights reserved. AD - Department of Surgery, Eulji University Hospital, Daejeon 302-799, South Korea Department of Radiology, Eulji University Hospital, Daejeon 302-799, South Korea Department of Urology, Eulji University Hospital, Daejeon 302-799, South Korea AU - Cho, M. K. AU - Lee, M. S. AU - Han, H. Y. AU - Woo, S. H. DB - Scopus DO - 10.3748/wjg.v20.i22.7075 IS - 22 KW - Fish bone Foreign body induced bowel perforation Foreign body ingestion Rectosigmoid colon perforation Urinary bladder M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2014 SP - 7075-7078 ST - Fish bone migration to the urinary bladder after rectosigmoid colon perforation T2 - World Journal of Gastroenterology TI - Fish bone migration to the urinary bladder after rectosigmoid colon perforation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84902125700&doi=10.3748%2fwjg.v20.i22.7075&partnerID=40&md5=8c8f9c0e8dee72e1378c6c597c8b768b VL - 20 ID - 1265 ER - TY - JOUR AB - Foreign body perforation of the gastrointestinal (GI) tract has diverse clinical manifestations, and the correct preoperative diagnosis is seldom made. We report the case of a 69-year-old woman who experienced severe pain in the right iliac fossa. The presumptive diagnosis was acute purulent appendicitis or diverticulitis. Multidetector computed tomography (MDCT) imaging showed the fish bone perforation of the terminal ileum. A high index of suspicion should always be maintained in order for the correct diagnosis to be made. AD - Department of Radiology, Sisli Florence Nightingale Hospital, Istanbul, Turkey Department of Radiology, Sisli Etfal Training and Research Hospital, Istanbul, Turkey AU - Mutlu, A. AU - Uysal, E. AU - Ulusoy, L. AU - Duran, C. AU - Selamoǧlu, D. DB - Scopus DO - 10.5505/tjtes.2012.90912 IS - 1 KW - Bowel perforation Fishbone Multidetector computed tomography M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2012 SP - 89-91 ST - Balık kılçıǧının neden olduǧu terminal ileum perforasyonu T2 - Ulusal Travma ve Acil Cerrahi Dergisi TI - A fish bone causing ileal perforation in the terminal ileum UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84855782155&doi=10.5505%2ftjtes.2012.90912&partnerID=40&md5=78e4a9dd0d2e9f270d0e4a5675500b86 VL - 18 ID - 1390 ER - TY - JOUR AB - BACKGROUND: We present a case of post-traumatic endophthalmitis with relatively good prognosis caused by Gordonia sputi, which, to our knowledge is the first case in the literature. CASE PRESENTATION: A 24 year old man, who underwent an intraocular foreign body extraction half a month before presentation in the left eye, was referred to us complaining of blurred vision and slight pain for 5 days. His first presentation showed moderate intracameral and intravitreous purulent inflammation with a best corrected vision of counting fingers. After gram staining of the intravitreous samples revealed a gram-positive bacilli infection, a combination of amikacin and vancomycin was initially injected intravitreously. The left eye kept stable for three days but deteriorated on the 4th day. On the 5th day after presentation conventional culture characterized the bacterium as an Actinomyces sp. while 16S ribosomal RNA gene sequencing confirmed it as Gordonia sputi. Thereby a complete pars plana vitrectomy combined with lensectomy and silicone oil tamponade was performed. During the surgery an intraocular irrigation with penicillin G was adopted, followed by administration of intravenous penicillin G twice one day for a week. A relatively normal fundus with slight intracameral inflammation was observed a week after the operation, and the best corrected vision recovered to 0.15. One year later his vision remained 0.1. CONCLUSION: Gordonia sputi should be taken into consideration in patients with post-traumatic endophthalmitis especially due to foreign body penetration. Compared to conventional laboratories, molecular methods are recommended for an accurate diagnosis. A comprehensive strategy of antimicrobial agents and vitrectomy may render a satisfactory result. AD - Ophthalmology Department of SIR RUN RUN SHAW hospital, SIR RUN RUN SHAW Institute of Clinical Medicine of Zhejiang University, #3 Qingchun East Road, Hangzhou, Zhejiang, 310016, People's Republic of China. Ophthalmology Department of SIR RUN RUN SHAW hospital, SIR RUN RUN SHAW Institute of Clinical Medicine of Zhejiang University, #3 Qingchun East Road, Hangzhou, Zhejiang, 310016, People's Republic of China. liyumin77@hotmail.com. AN - 29020920 AU - Fang, W. AU - Li, J. AU - Cui, H. S. AU - Jin, X. AU - Zhai, J. AU - Dai, Y. AU - Li, Y. C2 - PMC5637324 DA - Oct 11 DO - 10.1186/s12886-017-0573-5 DP - NLM ET - 2017/10/13 IS - 1 KW - Actinomycetales Infections/*diagnosis/microbiology/therapy Anti-Bacterial Agents/therapeutic use Combined Modality Therapy Endophthalmitis/*diagnosis/microbiology/therapy Endotamponade Eye Foreign Bodies/*diagnosis/microbiology/therapy Eye Infections, Bacterial/*diagnosis/microbiology/therapy Eye Injuries, Penetrating/*diagnosis/microbiology/therapy Gordonia Bacterium/genetics/*isolation & purification Humans Lens, Crystalline/surgery Male Penicillin G/therapeutic use RNA, Bacterial/genetics RNA, Ribosomal, 16S/genetics Silicone Oils/administration & dosage Vitrectomy Young Adult Actinomyces Case report Endophthalmitis Gordonia sputi Traumatic of Sir Run Run Shaw Hospital, also a well-known specialist majoring vitreoretinopathy and cataract in China. F.W., LJK., CHS., ZJ. and JXH. are fellows in this department. DYM. is a senior resident. All members of this group have experience in clinical treatment, animal models, cells culture, and genetic maneuvers of vitreoretinopathy. CONSENT FOR PUBLICATION: A written informed consent was obtained from the patient for publication of this Case report and any accompanying images. A copy of the written consent is available for review by the Editor of this journal. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. LA - eng N1 - 1471-2415 Fang, Wei Li, Jiuke Cui, Hu-Shan Jin, Xiaohong Zhai, Jing Dai, Yuanmin Li, Yumin Case Reports Journal Article BMC Ophthalmol. 2017 Oct 11;17(1):190. doi: 10.1186/s12886-017-0573-5. PY - 2017 SN - 1471-2415 SP - 190 ST - First identification of Gordonia sputi in a post-traumatic endophthalmitis patient - a case report and literatures review T2 - BMC Ophthalmol TI - First identification of Gordonia sputi in a post-traumatic endophthalmitis patient - a case report and literatures review VL - 17 ID - 199 ER - TY - JOUR AB - With an increase in aesthetic facial rejuvenation, there has been a higher demand for aesthetic treatment for the hands. Many different types of fillers are available to restore the smooth texture and its volume and elasticity. In majority of cases, fillers are considered to be safe and the complications are rare. The early complications such as bruising, paraesthesia and swelling are usually mild. Delayed or long-term complications are much rarer but of more concern. We report a case of 53-year-old woman with a filler-induced granulomatous reaction as a delayed complication, 2 years after her initial filler treatment. She presented with a 2-month history of worsening skin swelling and hardening, affecting exclusively the dorsa of her hands. She had no significant past medical history apart from breast implants 10 years ago. She reported that Ellanse rejuvenation hand filler was administered, 2 years before the onset of her hand swelling. To our knowledge, there have been no previous reports of granulomatous reactions due to Ellanse treatment. She was presented with woody-hard nodules over the dorsa of her hands that were tender on palpation. Differential diagnosis included sarcoidosis, filler-induced granulation, atypical bacterial infection and deep fungal infection. Blood test showed a normal full blood count, renal function, liver function test and slightly raised angiotensin-converting enzyme 62 (8-52). A deep incisional biopsy was done bilaterally and was reported consistent with a filler-induced granulomatous reaction. Tissue culture showed growth of 'Acinetobacter lwoffii'. Raised ACE was investigated to rule out any underlying systemic sarcoidosis, which may have predisposed her to the filler-induced granulomatous reaction. She was reviewed by respiratory physician, and both CXR and high resolution CT were normal. The slightly raised ACE was thus of no concern. She completed a course of doxycycline and ciprofloxacin. She received intralesional triamcinolone 10 mg/ml injection at week 6 and 16. This resulted in complete resolution of the nodules. Filler-related foreign body granulomas are nonallergic reactions that occur 6- 24 months after filler injections and are a form of chronic inflammatory reaction that is mainly composed of multinucleated giant cells. Foreign body granulomas may occur after the administration of any dermal filler. Treatment options include systemic antibiotics, lesional steroid injection and surgical excision. Although many patients end up having surgical removal, this should not be first line treatment. As our case has demonstrated, medical treatment can be substantial and with no permanent scarring due to surgery. AD - M. Ebadian, Queen Elizabeth, London, United Kingdom AU - Ebadian, M. AU - Chapman, A. DB - Embase KW - ciprofloxacin dipeptidyl carboxypeptidase doxycycline endogenous compound filler triamcinolone Acinetobacter lwoffii adult bacterial infection biopsy blood cell count breast endoprosthesis case report clinical article complication conference abstract contusion differential diagnosis drug combination drug toxicity excision female foreign body granuloma giant cell high resolution computer tomography human human cell human tissue injectable implant injection kidney function liver function test medical history middle aged mycosis nonhuman palpation paresthesia physician rejuvenation remission sarcoidosis scar formation skin swelling surgery tissue culture LA - English M3 - Conference Abstract N1 - L623095641 2018-07-25 PY - 2018 SN - 1365-2133 SP - 85 ST - Filler-induced granulomatous reaction two-years after the treatment T2 - British Journal of Dermatology TI - Filler-induced granulomatous reaction two-years after the treatment UR - https://www.embase.com/search/results?subaction=viewrecord&id=L623095641&from=export VL - 179 ID - 341 ER - TY - JOUR AB - Fourteen (8%) of 173 patients who had undergone cardiac operations or catheterization, or both, had fiber emboli in routine autopsy sections. All 14 patients had previous angiographic examinations; 8 had also had intracardiac operations, 3 had had extracardiac procedures such as pulmonary artery banding, and 3 patients had not been operated on. Fibers occurred most commonly in pulmonary arteries (8 cases) but were also found within renal (4 cases), cerebral (1 case) and mesenteric arteries (1 case). These fibers were readily distinguished from talc or starch. When they were found in patients who had died during or immediately after an intracardiac procedure there was no associated inflammation, and there may or may not have been thrombus. At a somewhat later stage, the fibers elicited a typical intravascular foreign body inflammatory reaction. Regardless of the type of reaction, the embolized fiber and the associated reaction often resulted in narrowing or occlusion of the vascular lumen. Fibers removed from cotton and paper materials were either straight or twisted, and many appeared to have a less birefringent central core. Cotton fibers were more homogeneously birefringent than paper fibers and were less variable in width. In the assessment of materials used in the operating room, the number of fibers trapped by the membrane filter was determined and graded as follows: 1+ (zero to 15); 2+ (16 to 30); 3+ (31 to 45); and 4+ (46 and greater). All drapes, gowns, caps, masks and sponges tested, whether cotton or paper, readily shed fibers upon agitation (3+ or 4+). There was no difference in shedding qualities between cotton and disposable paper. No difference in fiber count was found between control specimens (1+) and the saline wash from the pump oxygenator (1+). The presence of small numbers of fibers entrapped by the filter membrane from all control specimens was attributed to contamination by airborne fibers. AD - Dept. Ped., Child. Hosp. Med. Cent., Cincinnati, Ohio 45229 AU - Dimmick, J. E. AU - Bove, K. E. AU - McAdams, A. J. AU - Benzing Iii, G. DB - Embase Medline DO - 10.1056/NEJM197503272921308 IS - 13 KW - artery embolism autopsy brain embolism catheterization diagnosis embolism fiber foreign body heart catheterization heart surgery histology kidney artery embolism legal aspect lung embolism major clinical study mesenteric artery paper therapy LA - English M3 - Article N1 - L6049962 1976-01-01 PY - 1975 SN - 0028-4793 SP - 685-687 ST - Fiber embolization: a hazard of cardiac surgery and catheterization T2 - New England Journal of Medicine TI - Fiber embolization: a hazard of cardiac surgery and catheterization UR - https://www.embase.com/search/results?subaction=viewrecord&id=L6049962&from=export http://dx.doi.org/10.1056/NEJM197503272921308 VL - 292 ID - 687 ER - TY - JOUR AB - Background Fevers often arise after redo fundoplication with hiatal hernia repair. We reviewed our experience to evaluate the yield of a fever work-up in this population. Methods We performed a retrospective review of children undergoing redo Nissen fundoplication with hiatal hernia repair between December 2001 and September 2012. Temperatures and fever evaluations of those children receiving a mesh repair were compared with those without mesh. A fever defined as temperature ≥38.4°C. Results Fifty one children received 46 laparoscopic, 4 open, and 1 laparoscopic converted to open procedures. Biosynthetic mesh was used in 25 children whereas 26 underwent repair without mesh. A fever occurred in 56% of those repaired with mesh compared with 23.1% without mesh (P = 0.02). A fever evaluation was conducted in 32% of those with mesh compared with 11.5% without mesh (P = 0.52). A urinary tract infection was identified in one child after mesh use and an infection was identified in two children without mesh, one pneumonia and one wound infection (P = 1). In those repaired with mesh, there was no significant difference in maximum temperature. Conclusions Fever is common after redo Nissen fundoplication with hiatal hernia repair and occurs more frequently, and with higher temperatures in those with mesh. Fever work-up in these patients is unlikely to yield an infectious source and is attributed to the extensive dissection during the redo procedure. © 2014 Elsevier Inc. All rights reserved. AD - Department of Surgery, Children's Mercy Hospital and Clinics, 2401 Gillham Road, Kansas City, MO 64108, United States AU - Sharp, N. E. AU - Alemayehu, H. AU - Desai, A. AU - Holcomb Iii, G. W. AU - St. Peter, S. D. DB - Scopus DO - 10.1016/j.jss.2014.05.021 IS - 2 KW - Fever Hiatal hernia Mesh Nissen fundoplication Pediatric M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2014 SP - 594-597 ST - Fever after redo Nissen fundoplication with hiatal hernia repair T2 - Journal of Surgical Research TI - Fever after redo Nissen fundoplication with hiatal hernia repair UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84904258813&doi=10.1016%2fj.jss.2014.05.021&partnerID=40&md5=bb7ac675a34d963ea6b9d17b9a8c8294 VL - 190 ID - 1284 ER - TY - JOUR AB - Feeding tube placement for enteral nutrition (EN) support is widely used in both critically ill and stable chronically ill patients who are unable to meet their nutrition needs orally. Nasal or oral feeding tubes can be performed blindly at the bedside or with fluoroscopic or endoscopic guidance into the stomach or small bowel. Percutaneous feeding tubes are used when EN support is required for longer periods (>4-6 weeks) and are most commonly placed endoscopically or radiographically. Although generally safe and effective, there is a wide spectrum of known complications associated with feeding tube placement. Errors made at the time of feeding tube placement can result in a number of these procedural and postprocedural complications. In many cases, a single error at the time of placement can result in numerous complications. A thorough knowledge of these errors and avoiding them in practice will decrease iatrogenic complications in a vulnerable population. In addition, early recognition and management of complications will further minimize morbidity and even mortality in enteral feeding tube placement. This article reviews the common errors leading to complications of enteral feeding tube placement and their prevention and management. © 2012 American Society for Parenteral and Enteral Nutrition. AD - Department of Internal Medicine, University of Utah, Salt Lake City, UT, United States Beth Israel Medical Center, York, NY, United States College of Pharmacy and Toxicology, University of Utah, Salt Lake City, UT, United States Division of Gastroenterology, University of Utah, 30 N 1900 E, 4R118 SOM, Salt Lake City, UT 84132, United States AU - Stayner, J. L. AU - Bhatnagar, A. AU - McGinn, A. N. AU - Fang, J. C. DB - Scopus DO - 10.1177/0884533612462239 IS - 6 KW - enteral nutrition gastrostomy jejunostomy nutritional support M3 - Review N1 - Cited By :39 Export Date: 10 November 2020 PY - 2012 SP - 738-748 ST - Feeding tube placement: Errors and complications T2 - Nutrition in Clinical Practice TI - Feeding tube placement: Errors and complications UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84868711371&doi=10.1177%2f0884533612462239&partnerID=40&md5=9379a5812a326d3286de2780431b4535 VL - 27 ID - 1350 ER - TY - JOUR AB - Purpose: We aimed to document the clinical usefulness of uncalcined and unsintered hydroxyapatite (u-HA) particles and poly-L-lactide (PLLA) composite materials and their advantageous properties. Methods: Between April 2016 and March 2018, five patients required anterior maxillary alveolar ridge augmentation using fixation with u-HA/PLLA screws for an onlay block bone graft harvested from the mandibular ramus at our institute. Bone biopsies were obtained from the dental implantation site following bone healing for histomorphometric and immunohistochemical (IHC) measurements. Results: Many stromal cells were positive for Osterix, RUNX2, and SOX9 but were negative for CD68. On cell counting, based on IHC staining for Osterix, RUNX2, SOX9 and CD68 from peripheral u-HA/PLLA screw or bone areas, both areas consistently showed no significant difference in terms of Osterix, RUNX2, and SOX9. Hematoxylin-eosin staining revealed direct bone connection to the biomaterials, and no inflammatory cells infiltrated the areas surrounding the bone or artificial material. Area between the bone and u-HA/PLLA screw was seamless with no boundary. Round small cells and immature fibroblasts were noted. The new bone showed the presence of bone lamellae, normal osteocytes, and osteoblasts. Conclusion: The u-HA/PLLA materials showed excellent biodegradability and bioactive osteoconductivity. In addition, this material induced no apparent inflammatory or foreign body reactions following implantation, and it directly bonded to the human bone. Therefore, this u-HA/PLLA material seems ideal and most suitable for use as a substitute for osteosynthesis. AD - Division of Oral and Maxillofacial Surgery, Kagawa Prefectural Central Hospital, Takamatsu, Japan. Department of Oral Pathology and Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. Department of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine, Shimane, Japan. AN - 30745812 AU - Sukegawa, S. AU - Kawai, H. AU - Nakano, K. AU - Kanno, T. AU - Takabatake, K. AU - Nagatsuka, H. AU - Furuki, Y. C2 - PMC6367538 DO - 10.7150/ijms.27986 DP - NLM ET - 2019/02/13 IS - 2 KW - Adult Aged Alveolar Bone Grafting/*instrumentation Antigens, CD/metabolism Antigens, Differentiation, Myelomonocytic/metabolism Core Binding Factor Alpha 1 Subunit/metabolism *Dental Implants Durapatite Female Humans Male Middle Aged Pilot Projects Polyesters SOX9 Transcription Factor/metabolism Sp7 Transcription Factor/metabolism Stromal Cells/metabolism Poly-L-lactide biodegradability bone regeneration osteoconductivity uncalcined and unsintered hydroxyapatite LA - eng N1 - 1449-1907 Sukegawa, Shintaro Kawai, Hotaka Nakano, Keisuke Kanno, Takahiro Takabatake, Kiyofumi Nagatsuka, Hitoshi Furuki, Yoshihiko Journal Article Int J Med Sci. 2019 Jan 1;16(2):311-317. doi: 10.7150/ijms.27986. eCollection 2019. PY - 2019 SN - 1449-1907 SP - 311-317 ST - Feasible Advantage of Bioactive/Bioresorbable Devices Made of Forged Composites of Hydroxyapatite Particles and Poly-L-lactide in Alveolar Bone Augmentation: A Preliminary Study T2 - Int J Med Sci TI - Feasible Advantage of Bioactive/Bioresorbable Devices Made of Forged Composites of Hydroxyapatite Particles and Poly-L-lactide in Alveolar Bone Augmentation: A Preliminary Study VL - 16 ID - 224 ER - TY - JOUR AB - Since its introduction in 2001, Wireless Video Capsule enteroscopy is gaining acceptance due to its high diagnostic potential and minimal risk. In some centers, it offers an alternative approach to visualize the small intestine and to evaluate patients with suspected small bowel disease. We present a series of known complications of this procedure and call for a more proactive role in the management of retained capsule. AD - Department of Surgery, North Shore University Hospital, Manhasset, NY, United States Department of Surgery, North Shore University Hospital, 300 Community Drive, Manhasset, NY 11030, United States AU - Agaba, E. A. AU - Shamseddeen, H. AU - Sasthakonar, V. AU - Sivalingham, V. AU - Shah, K. G. AU - Ravikumar, T. S. AU - Nadjari, H. AU - Denoto, G. DB - Scopus IS - 11 M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2007 SP - 1140-1143 ST - Fate of retained capsule: A pathognomonic for surgery T2 - American Surgeon TI - Fate of retained capsule: A pathognomonic for surgery UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-38449110520&partnerID=40&md5=869a4121ec86b89e234693ded32079a6 VL - 73 ID - 1549 ER - TY - JOUR AB - STUDY DESIGN: We report a case of pulmonary embolism of polymethylmethacrylate material after percutaneous vertebroplasty. OBJECTIVE: To describe a severe vertebroplasty complication, the pulmonary embolism, which proved to be fatal in a patient with many chronic disabilities. SUMMARY OF BACKGROUND DATA: Until 2007, the literature noted that the risk of embolism of polymethylmethacrylate after a percutaneous vertebroplasty counted a small number of pulmonary cement embolism and a smaller number of fatal consequences. The most recent research revealed that the risk of a pulmonary cement embolism ranges from 3.5% to 23% for osteoporotic compression fractures. METHODS: This study is a case report of an 80-year-old patient with multiple medical comorbid factors, chronic obstructive pulmonary disease, mild renal failure, osteoporosis, and hepatic cirrhosis. Symptoms of pulmonary embolism developed 1 month after a percutaneous vertebroplasty. An echocardiography report suggested that the cement infiltrated the right atrium and the right pulmonary artery, and this was confirmed by a computed tomographic scan. As the therapy with oxygen and low-molecular-weight heparin failed to solve the thrombus, the patient required a surgical tricuspid annuloplasty and the extirpation of the right atrial and right pulmonary masses. RESULTS: The course of the operation was complicated by pulmonary infection, and the patient ultimately succumbed to infection/respiratory failure. CONCLUSION: The presence of intravascular/intracardiac foreign bodies is underreported in literature, but it is quite common in clinical practice. We need to discuss the choice of some non-risk-free interventions such as vertebroplasty in older patients already affected by multiple main disabilities. AD - Cardiology Division, Internal Medicine Department, Ospedale Civico di Chivasso (Turin), Italy. AN - 22422441 AU - Franco, E. AU - Frea, S. AU - Solaro, C. AU - Conti, V. AU - Pinneri, F. DA - Mar 15 DO - 10.1097/BRS.0b013e318230db1b DP - NLM ET - 2012/03/17 IS - 6 KW - Aged, 80 and over Bone Cements/*adverse effects Fatal Outcome Humans Male Pulmonary Embolism/*etiology Vertebroplasty/*adverse effects LA - eng N1 - 1528-1159 Franco, Erica Frea, Simone Solaro, Cristina Conti, Valentina Pinneri, Francesco Case Reports Journal Article United States Spine (Phila Pa 1976). 2012 Mar 15;37(6):E411-3. doi: 10.1097/BRS.0b013e318230db1b. PY - 2012 SN - 0362-2436 SP - E411-3 ST - Fatal pulmonary embolism: when the cause is not a thrombus T2 - Spine (Phila Pa 1976) TI - Fatal pulmonary embolism: when the cause is not a thrombus VL - 37 ID - 124 ER - TY - JOUR AD - Center for Shoulder, Elbow, Sports Med., New York Orthoped. H., New York, NY, United States Department of Orthopaedic Surgery, Columbia University, 622 W 168th St, PH 11th Floor, 10032, New York, NY, United States AU - Stewart, A. M. AU - Ahmad, C. S. DB - Scopus DO - 10.1016/j.jse.2004.01.027 IS - 5 M3 - Article N1 - Cited By :17 Export Date: 10 November 2020 PY - 2004 SP - 558-561 ST - Failure of acromioclavicular reconstruction using Gore-Tex graft due to aseptic foreign-body reaction and clavicle osteolysis: A case report T2 - Journal of Shoulder and Elbow Surgery TI - Failure of acromioclavicular reconstruction using Gore-Tex graft due to aseptic foreign-body reaction and clavicle osteolysis: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-4544386448&doi=10.1016%2fj.jse.2004.01.027&partnerID=40&md5=9cbb7bd02ce632c253a22e452a74db34 VL - 13 ID - 1622 ER - TY - JOUR AD - Nurse Educator Perioperative Nursing, St Vincent's Hospital, Darlinghurst NSW 2010 AN - 106701678. Language: English. Entry Date: 20040213. Revision Date: 20150820. Publication Type: Journal Article AU - Butler, M. AU - Boxer, E. AU - Sutherland-Fraser, S. DB - ccm DP - EBSCOhost IS - 1 KW - Documentation Human Error Surgical Count Procedure Data Analysis Software Descriptive Research Descriptive Statistics New South Wales Operating Rooms Perioperative Nursing Pilot Studies Quantitative Studies Registered Nurses Research Instruments Surgery, Operative -- Classification Time Factors Human N1 - research; tables/charts. Journal Subset: Australia & New Zealand; Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. PY - 2003 SN - 1448-7535 SP - 10-14 ST - The factors that contribute to count and documentation errors in counting: a pilot study T2 - ACORN: The Journal of Perioperative Nursing in Australia TI - The factors that contribute to count and documentation errors in counting: a pilot study UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106701678&site=ehost-live&scope=site VL - 16 ID - 869 ER - TY - JOUR AB - The success of surgical procedures is largely dependent upon an orderly process of repair and wound healing and although we do not recount these daily, understanding of the available knowledge will inf luence the attitudes, techniques, and philosophies of the surgeon and lead to better overall patient care. Some factors of wound healing are entirely beyond the control of the surgeon while many factors of technique and wound management affecting the process of wound healing are within the control of the surgeon and are of practical importance in every surgical procedure. This presentation reviews the current concepts of wound repair, mentions those over which we have little control, and points out factors over which the surgeon does exert an influence and relates these to optimal wound care and satisfactory wound healing. © The American Laryngological, Rhinological & Otological Society, Inc. AD - Ann Arbor, MI, United States AU - Dingman, R. O. DB - Scopus DO - 10.1288/00005537-197309000-00012 IS - 9 M3 - Article N1 - Cited By :15 Export Date: 10 November 2020 PY - 1973 SP - 1540-1554 ST - Factors of clinical significance affecting wound healing T2 - Laryngoscope TI - Factors of clinical significance affecting wound healing UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015811713&doi=10.1288%2f00005537-197309000-00012&partnerID=40&md5=d73038c150b228e13bf0cd0565bc03a5 VL - 83 ID - 1783 ER - TY - JOUR AB - Objectives: Humans receiving tissue-engineered tracheal grafts have experienced poor outcomes ultimately resulting in death or the need for graft explantation. We assessed the performance of the synthetic scaffolds used in humans with an ovine model of orthotopic tracheal replacement, applying standard postsurgical surveillance and interventions to define the factors that contributed to the complications seen at the bedside. Study Design: Large animal model. Setting: Pediatric academic research institute. Subjects and Methods: Human scaffolds were manufactured with an electrospun blend of polyethylene terephthalate and polyurethane reinforced with polycarbonate rings. They were seeded with autologous bone marrow–derived mononuclear cells and implanted in sheep. Animals were evaluated with routine bronchoscopy and fluoroscopy. Endoscopic dilation and stenting were performed to manage graft stenosis for up to a 4-month time point. Grafts and adjacent native airway were sectioned and evaluated with histology and immunohistochemistry. Results: All animals had signs of graft stenosis. Three of 5 animals (60%) designated for long-term surveillance survived until the 4-month time point. Graft dilation and stent placement resolved respiratory symptoms and prolonged survival. Necropsy demonstrated evidence of infection and graft encapsulation. Granulation tissue with signs of neovascularization was seen at the anastomoses, but epithelialization was never observed. Acute and chronic inflammation of the native airway epithelium was observed at all time points. Architectural changes of the scaffold included posterior wall infolding and scaffold delamination. Conclusions: In our ovine model, clinically applied synthetic tissue-engineered tracheas demonstrated infectious, inflammatory, and mechanical failures with a lack of epithelialization and neovascularization. © American Academy of Otolaryngology–Head and Neck Surgery Foundation 2019. AD - Division of Pediatric Surgery, Loma Linda Children’s Hospital, Loma Linda, CA, United States Center for Regenerative Medicine, Research Institute at Nationwide Children’s Hospital, Columbus, OH, United States Biomedical Sciences Graduate Program, College of Medicine, The Ohio State University, Columbus, OH, United States Department of Pathology, The Ohio State University, Columbus, OH, United States Department of Otolaryngology, Texas Tech University Health Sciences Center, Lubbock, TX, United States Department of General Surgery, The Ohio State University, Columbus, OH, United States College of Medicine, The Ohio State University, Columbus, OH, United States Department of Otolaryngology–Head and Neck Surgery, Nationwide Children’s Hospital, Columbus, OH, United States Center for Perinatal Research, Research Institute at Nationwide Children’s Hospital, Columbus, OH, United States Nanofiber Solutions Inc, Hilliard, OH, United States Department of Pediatric Surgery, Nationwide Children’s Hospital, Columbus, OH, United States AU - Pepper, V. AU - Best, C. A. AU - Buckley, K. AU - Schwartz, C. AU - Onwuka, E. AU - King, N. AU - White, A. AU - Dharmadhikari, S. AU - Reynolds, S. D. AU - Johnson, J. AU - Grischkan, J. AU - Breuer, C. K. AU - Chiang, T. DB - Scopus DO - 10.1177/0194599819844754 IS - 3 KW - biomaterials regenerative medicine stem cells tissue engineering trachea M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2019 SP - 458-467 ST - Factors Influencing Poor Outcomes in Synthetic Tissue-Engineered Tracheal Replacement T2 - Otolaryngology - Head and Neck Surgery (United States) TI - Factors Influencing Poor Outcomes in Synthetic Tissue-Engineered Tracheal Replacement UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065257455&doi=10.1177%2f0194599819844754&partnerID=40&md5=e6fc05c5b8d5cb1b13161789ebbbdf45 VL - 161 ID - 1002 ER - TY - THES AB - Determining the factors that are associated with medical errors is crucial for today's operating room environment. Estimations of errors occurring while patients are in the operating room range from 35% to 66% and research demonstrates that the majority of these errors are preventable. One persistent but poorly understood error in the operating room is incorrect surgical counts. This cross-sectional study provided evidence regarding factors influencing incorrect surgical counts in the operating room.The Quality Health Outcomes Model guided a review of the literature for variable section and hypothesis development. Data abstracted from electronic perioperative medical records and primary data collected from perioperative nurses was used to determine factors central in the prediction of incorrect surgical counts. Additionally, the rate of incorrect surgical counts of the operating rooms involved in the study was determined.Findings indicate that patient characteristics (lower body-mass index and poorer physical status), staff involvement (multiple surgical teams and a greater number of perioperative nurses), and intraoperative circumstances (difficult procedures, emergencies or procedures with unexpected changes) are associated with the occurrence of an incorrect surgical count. In this study, nurse characteristics (education, experience, certification, and employer status) were not significantly associated with an incorrect surgical count.Identification of the risk factors shown in this study to be important may influence patient safety practices and operating room policy to reduce these types or errors. The implementation and use of standardized organizational regulations and strict adherence to standards developed by the Association of periOperative Registered Nurses should be continuously emphasized. Additional patient safety practices may be indicated for patients with higher risks of incorrect surgical counts. AU - Rowlands, Aletha Elizabeth DB - ccm DP - EBSCOhost KW - Health Care Errors Operating Rooms -- Standards Surgical Count Procedure Cross Sectional Studies Human Models, Theoretical Record Review M1 - Ph.D. N1 - Accession Number: 109855101. Language: English. Entry Date: 20120622. Revision Date: 20150923. Publication Type: Doctoral Dissertation; research. UMI Order AAI3446423 PB - University of Virginia PY - 2010 SN - 9781124498669 SP - 167 p-167 p ST - Factors Influencing Incorrect Surgical Counts in the Operating Room TI - Factors Influencing Incorrect Surgical Counts in the Operating Room UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109855101&site=ehost-live&scope=site ID - 926 ER - TY - JOUR AB - Background: Retained foreign objects (RFOs) can cause negative outcomes for patients such as infection, increased length of hospitalization, and death. Surgical counts are associated with a reduced likelihood of an RFO but the counting process is complex and prone to human error. To improve count accuracy the risk factors for a discrepancy must be identified so that mitigation strategies can be applied. Objective: To identify the factors that contribute to surgical count discrepancies in order to provide mitigation strategies that will improve patient safety in the operating room. Methods: An analysis of a sample of 1067 incident reports describing incorrect surgical counts was conducted. Reports were double-coded, by three specialists, on dimensions that included most likely contributing factor for the discrepancy, type and number of items involved, and actions taken to attempt to reconcile the count. Results: Needles were most commonly involved in count discrepancies. The next most common was instruments. The most common factors reported as contributing to an incorrect count were item(s) being dropped, item(s) not counted during initial count, large case, packing related issue, and change in procedure. An x-ray was conducted in 71% of the reports but only 25% specified it was located in the operating theatre. Additional search strategies were used in a small proportion of reports and included the use of a magnet and microscope. Conclusion: Surgical counting is a complex process and, in order to ensure count accuracy, a system-based solution is required. Recommended solutions are provided in order to reduce the likelihood of an error. Contexte : Les corps étrangers oubliés peuvent produire des résultats négatifs pour les patients, comme de l'infection, une hospitalisation prolongée et le décès. Les décomptes chirurgicaux sont associés à une probabilité réduite de corps étrangers oubliés, mais le processus du décompte est complexe et sujet à l'erreur humaine. Afin d'améliorer l'exactitude du décompte, on doit déterminer les facteurs de risque liés aux divergences pour pouvoir appliquer des stratégies d'atténuation. Objectif : Pour déterminer les facteurs contribuant aux divergences lors des décomptes chirurgicaux afin de fournir des stratégies d'atténuation qui amélioreront la sécurité du patient en salle d'opération. Méthodes : L'analyse d'un échantillon de 1 067 rapports d'incidents décrivant des décomptes chirurgicaux incorrects a été menée. Les rapports étaient doublement codés, par trois spécialistes, par rapport à des cotes qui incluaient le facteur contributif le plus probable pour la divergence, le type et le nombre d'éléments impliqués ainsi que les actions prises pour essayer de réconcilier le décompte. Résultats : Les aiguilles étaient plus souvent en cause dans les divergences de décomptes. Les instruments occupaient la deuxième place. Les facteurs les plus courants signalés comme contribuant à un décompte incorrect étaient les articles ayant été échappés, les articles qui n'avaient pas été comptés lors du premier compte, les cas lourds, les problèmes liés au tamponnement et les changements d'intervention. Un rayon X a été effectué dans 71 % des rapports, mais seulement 25 % ont précisé qu'il avait été fait en bloc opératoire. Des stratégies de recherche additionnelles ont été utilisées dans une petite proportion des rapports et incluaient l'utilisation d'un aimant et d'un microscope. Conclusion : Le décompte chirurgical est un processus complexe et, dans le but de s'assurer de l'exactitude du décompte, une solution basée sur un système est nécessaire. Afin de réduire les probabilités d'erreurs, on a fourni des recommandations. AD - Human Factors Specialist, Alberta Health Services, Calgary, AB, Canada Director - Human Factors and Evaluation, Alberta Health Services, Calgary, AB, Canada Executive Director - Surgery Strategic Clinical Network, Alberta Health Services, Calgary, AB, Canada AN - 139763212. Language: English. Entry Date: 20191128. Revision Date: 20200529. Publication Type: Article AU - Bubric, Katherine AU - Martel, Jessica AU - Laberge, Jason AU - Litvinchuk, Stacey DB - ccm DP - EBSCOhost IS - 4 KW - Surgical Count Procedure -- Psychosocial Factors Retained Instruments -- Prevention and Control Patient Safety Operating Rooms Quality Improvement Human Incident Reports Needles Surgical Instruments X-Rays Microscopy Descriptive Statistics Voluntary Reporting N1 - forms; research; tables/charts. Journal Subset: Blind Peer Reviewed; Canada; Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. PY - 2019 SN - 1927-6141 SP - 13-38 ST - FACTORS CONTRIBUTING TO INCORRECT SURGICAL COUNTS AND SYSTEM-BASED PREVENTION STRATEGIES T2 - ORNAC Journal TI - FACTORS CONTRIBUTING TO INCORRECT SURGICAL COUNTS AND SYSTEM-BASED PREVENTION STRATEGIES UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=139763212&site=ehost-live&scope=site VL - 37 ID - 701 ER - TY - JOUR AB - In summary, the following program should be useful for the physician who encounters a child with a suspected eye injury: 1. Obtain a history. What was the child doing when he hurt his eye? 2. Examine the child by first inspecting the lids. Evert the lids with a cotton tipped applicator if necessary and if the globe is intact. Look at the canalicular area and decide whether the lacrimal drainage system is disrupted. Is a lid laceration deep enough to affect the levator? Could the orbital rim or any bony structures be involved? Should an x-ray film for fracture or foreign body be obtained? Is the anterior segment of the globe intact? What is the condition of the conjunctiva and cornea? Should fluorescein stain be applied to the cornea in an attempt to determine the presence of corneal abrasion? Put proparacaine hydrochloride 0.5 per cent drops in the eye if it is too sensitive or photophobic to allow opening of the lids. Is there blood in the anterior chamber? Does the lens look opaque? Is the cornea lacerated, is the globe ruptured? Does the patient have double vision? Is the eye obviously displaced relative to the other eye? 3. Check visual acuity-! Visual acuity may be checked initially or after examination of the eye, but some recording of the visual acuity should always be made. An elegent chart is not necessary. The child may be asked to identify letters on a prescription pad or merely record the presence of light, count fingers, etc., whichever is nearest maximal visual potential. 4. A decision should be made with regard to further diagnostic techniques including the decision, should an ophthalmologist be consulted? 5. Treat minimal anterior segment or adnexal injuries with or without consultation with an ophthalmologist. 6. If the injury is extensive, resist the urge to do something immediately; merely patch the eye and put the child in the hands of an ophthalmologist. AN - 1124229 AU - Helveston, E. M. DA - May DO - 10.1016/s0031-3955(16)33149-2 DP - NLM ET - 1975/05/01 IS - 2 KW - Child Conjunctiva/surgery Corneal Injuries Eye Foreign Bodies/complications/diagnosis *Eye Injuries/complications/diagnosis/drug therapy/etiology/surgery/therapy Eyelids/injuries/surgery Fractures, Bone/diagnosis Humans Hyphema/etiology Lens, Crystalline/injuries Mydriatics/therapeutic use Orbit/injuries Pediatrics Sulfacetamide/therapeutic use Uveitis/etiology LA - eng N1 - Helveston, E M Journal Article United States Pediatr Clin North Am. 1975 May;22(2):501-11. doi: 10.1016/s0031-3955(16)33149-2. PY - 1975 SN - 0031-3955 (Print) 0031-3955 SP - 501-11 ST - Eye trauma in childhood T2 - Pediatr Clin North Am TI - Eye trauma in childhood VL - 22 ID - 3 ER - TY - JOUR AB - PURPOSE: The purpose of this study was to examine the relationship between extraprostatic seed placement and seed loss in a cohort of patients who had underwent both computed tomographic (CT) and magnetic resonance (MR) scans at day 0 and day 30 following brachytherapy. MATERIALS AND METHODS: Twenty-two patients with 1997 AJC clinical stage T1-T2 prostatic carcinoma were implanted with nonstranded I 125. Patients were selected solely by having a prostate volume between 15 and 60 cc and a willingness to return for 30-day follow-up CT and MR scans. The total number of I-125 sources implanted on day 0 ranged from 50 to 104 (median: 70). Preplan treatment planning methods have been previously described in detail: a modified peripheral loading pattern and treatment margins of 5-10 mm were used. Noncontrast postimplantation CT and MR scans were obtained 1-4 hours after implantation on day 0. The total seed count on days 0 and 30 was verified by plain radiograph. Pelvic MR (T1) images were registered with the CT images in the Varian planning system, using bony landmarks. The number of extracapsular seeds in each quadrant of the circumference was then totaled for each patient. A second set of plain radiographs (for seed counting), as well as CT and MR scans, were obtained 30 days after implantation (day 30) and were similarly analyzed. RESULTS: The number of extraprostatic seeds at day 0 ranged from 13 to 35, making up 17%-48% (median: 34%) of the total number implanted. Of the 22 patients, 10 lost one or more seeds between the implantation day and the 1-month follow-up. The mean number of seeds lost was 1.1 (± 1.7). There was no apparent relationship between the percent of extraprostatic seeds and the number of seeds lost. There was no apparent relationship between seed loss and number of seeds less than 3 mm or greater than 3 mm from the prostatic capsule. CONCLUSIONS: We have shown here that with CT and MR seed localization, extraprostatic seed placement does not appear to substantially increase the likelihood of seed loss after the procedure. Copyright © 2005 Jones and Bartlett Publishers, Inc. AD - Department of Radiation Oncology, McGill University, Montreal, Que., Canada Department of Radiation Oncology, Puget Sound Health Care System, Department of Veterans Affairs, Seattle, WA, United States Department of Radiation Oncology, Department of Pathology, University of Washington, Seattle, WA, United States Group Health Cooperative, Seattle, WA, United States Department of Diagnostic Radiology, Puget Sound Health Care System, Department of Veterans Affairs, Seattle, WA, United States Schiffler Cancer Center, Wheeling, WV, United States Radiation Oncology (#174), Department of Veterans Affairs, 1660 S. Columbian Way, Seattle, WA 98108-1597, United States AU - Nedea, E. AU - Wallner, K. AU - Reed, D. AU - Ford, E. AU - Sutlief, S. AU - Mueller, A. AU - Maki, J. AU - Merrick, G. DB - Scopus DO - 10.1097/00130404-200503000-00010 IS - 2 KW - Brachytherapy CT MR Prostate cancer M3 - Article N1 - Cited By :8 Export Date: 10 November 2020 PY - 2005 SP - 147-151 ST - Extraprostatic seed placement and its effect on seed loss T2 - Cancer Journal TI - Extraprostatic seed placement and its effect on seed loss UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33749583167&doi=10.1097%2f00130404-200503000-00010&partnerID=40&md5=6378e7029b27c3d4252b502a360383a1 VL - 11 ID - 1611 ER - TY - JOUR AB - Meckel's diverticulum is the commonest congenital anomaly of the small intestine. It can, however, present acutely relating to a number of complications that may require emergency surgery and possible bowel resection. Perforation is a rare complication and there are only seven cases reported of an inflamed Meckel's diverticulum due to a chicken bone. Laparoscopic repair of Meckel's diverticulum-associated complications has gained popularity over the recent years. We present a case of chicken bone perforation that was treated with laparoscopic-assisted extracorporeal resection of the affected small bowel segment. Copyright 2015 BMJ Publishing Group. All rights reserved. AD - Department of General Surgery, Lewisham and Greenwich NHS Trust, London, United Kingdom AU - Nikolopoulos, I. AU - Ntakomyti, E. AU - El-Gaddal, A. AU - Corry, D. C7 - e209051 DB - Scopus DO - 10.1136/bcr-2014-209051 M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2015 ST - Extracorporeal laparoscopically assisted resection of a perforated Meckel's diverticulum due to a chicken bone T2 - BMJ Case Reports TI - Extracorporeal laparoscopically assisted resection of a perforated Meckel's diverticulum due to a chicken bone UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84928922744&doi=10.1136%2fbcr-2014-209051&partnerID=40&md5=6f7fe112647eb113e50a8dba9d375c9f VL - 2015 ID - 1232 ER - TY - JOUR AB - The purpose of this study was to observe extracellular matrix remodeling in children with airway foreign-body aspiration (FBA) by detecting the expression of matrix metalloproteinase-9 (MMP-9), tissue inhibitor of matrix metalloproteinase-1 (TIMP-1), and hydroxyproline (HYP) in bronchoalveolar lavage fluid (BALF). Forty-six children with FBA and 12 control subjects from 2002-2003 were enrolled in this study. The former were divided into three subgroups according to duration of foreign-body (FB) retention (subgroup 1, <7 days; subgroup 2, 7-30 days; subgroup 3, >30 days). Cell count, and levels of MMP-9, TIMP-1, and HYP in BALF were measured. The total number of cells and differential counts detected in BALF did not differ significantly between patients and controls (P > 0.05), while mast cells were found only in the BALF of patients. The positive rates of MMP-9 in controls, subgroup 1, subgroup 2, and subgroup 3 were 33.3%, 62.5%, 80.0%, and 93.3%, respectively, with a significant difference (P = 0.006). The positive rate of TIMP-1 in controls and subgroups 1, 2, and 3 were 33.3%, 62.5%, 80.0%, and 93.3%, respectively, with a significant difference (P < 0.001) as well. HYP levels in subgroups 2 and 3 were significantly more increased than in subgroup 1 and controls (all P < 0.001). Levels of MMP-9, TIMP-1, and HYP in patients were positively correlated with duration of FB retention (all P < 0.05), and levels of MMP-9 and TIMP-1 were also positively correlated with percentage of mast cells in BALF (all P < 0.05). The differences in MMP-9 and TIMP-1 before and after FB removed were not significant (P > 0.05), while HYP levels decreased significantly after FB were removed (P = 0.001). Our findings support the hypothesis that FBA may contribute not only to mechanical airway obstruction, but also possibly to eventual airway remodeling by generation of MMPs and TIMPs. AD - Department of Respiratory Medicine, Zhejiang University Children's Hospital, School of Medicine, Zhugan Xiang, Hangzhou, China. AN - 15211698 AU - Tang, L. F. AU - Du, L. Z. AU - Chen, Z. M. AU - Zou, C. C. DA - Aug DO - 10.1002/ppul.20071 DP - NLM ET - 2004/06/24 IS - 2 KW - Airway Obstruction/etiology/*pathology Bronchoalveolar Lavage Fluid/chemistry/cytology Bronchoscopy Case-Control Studies Child, Preschool Extracellular Matrix/enzymology/*pathology Female Foreign Bodies/complications/*pathology Humans Hydroxyproline/analysis Immunohistochemistry Infant Male Matrix Metalloproteinase 9/analysis Tissue Inhibitor of Metalloproteinase-1/analysis *Trachea LA - eng N1 - Tang, Lan Fang Du, Li Zhong Chen, Zhi Min Zou, Chao Chun Journal Article United States Pediatr Pulmonol. 2004 Aug;38(2):140-5. doi: 10.1002/ppul.20071. PY - 2004 SN - 8755-6863 (Print) 1099-0496 SP - 140-5 ST - Extracellular matrix remodeling in children with airway foreign-body aspiration T2 - Pediatr Pulmonol TI - Extracellular matrix remodeling in children with airway foreign-body aspiration VL - 38 ID - 49 ER - TY - JOUR AB - The low canine colon anastomosis heals best when bacterial contamination is minimal, the anastomosis is not drained, and the anastomosis is intraperitoneal. A drain makes intraperitoneal sepsis worse and is harmful to the peritoneal cavity. Silastic drains are less harmful than latex and vinyl drains. Local sepsis interferes with colon healing. AD - Surg. Res. Serv., VA Hosp., Memphis, Tenn., United States AU - Crowson, W. N. AU - Wilson, C. S. DB - Scopus IS - 11 M3 - Article N1 - Cited By :19 Export Date: 10 November 2020 PY - 1973 SP - 597-601 ST - An experimental study of the effects of drains on colon anastomoses T2 - American Surgeon TI - An experimental study of the effects of drains on colon anastomoses UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015887005&partnerID=40&md5=c13bbbc08217fc689b0c432292b8d3db VL - 39 ID - 1781 ER - TY - JOUR AB - The authors evaluated the long-term safety of expanded polytetrafluoroethylene (ePTFE) implants used in external valvuloplasty for treatment of incompetence of the long saphenous and common and superficial femoral veins. During a 15-year period patients with superficial and/or deep venous disease and hypertension due to pure superficial or deep vein incompetence underwent an external valvuloplasty with ePTFE sutures, or an ePTFE cardiovascular patch placed as a sleeve around the incompetent vein segment, or an ePTFE tubular graft placed around the venous segment. Postoperative follow-up evaluations consisted of clinical examinations, high-resolution ultrasonography, and color duplex scanning, and a complete blood count performed at 1, 3 and 6 months, and repeated for at least 4 years, every 2 years after the procedure. A total of 101 patients (38 men and 63 women; mean [+/- sd] age, 44+/-12 years) underwent external valvuloplasty between January 1983 and December 1998; 82 of them completed the 4-year follow-up. Forty of the 82 patients had been operated on for superficial vein incompetence, 42 for deep vein incompetence. Overall, the mean follow-up time was 7.8+/-3.6 years (range, 4 to 13). There were no infections, thromboses,foreign-body reactions to the ePTFE implants, or other prosthesis-related complications requiring explantation. One granuloma (noninfected) developed in association with a tubular ePTFE implant around a long saphenous vein, but it did not necessitate implant removal. Seven patients required (at least after 4 years) a second procedure for recurrent or new venous incompetence. Therefore, in this observational study, ePTFE implants used to treat or correct venous incompetence were well tolerated on a long-term basis. AD - Cardiovascular Institute, Chieti University, Pescara, Italy. cardres@pe.abol.it AN - 10959508 AU - Belcaro, G. AU - Nicolaides, A. N. AU - Errichi, B. M. AU - Incandela, L. AU - De Sanctis, M. T. AU - Laurora, G. AU - Ricci, A. DA - Aug DO - 10.1177/000331970005100804 DP - NLM ET - 2000/08/26 IS - 8 Pt 2 KW - Adult Female Femoral Vein/*pathology/surgery Humans Leg/blood supply Male Middle Aged Polytetrafluoroethylene/*therapeutic use Prosthesis Implantation Saphenous Vein/*pathology/surgery Surgical Mesh Sutures Treatment Outcome Vascular Surgical Procedures/*instrumentation/methods Venous Insufficiency/*surgery LA - eng N1 - Belcaro, G Nicolaides, A N Errichi, B M Incandela, L De Sanctis, M T Laurora, G Ricci, A Clinical Trial Journal Article United States Angiology. 2000 Aug;51(8 Pt 2):S27-32. doi: 10.1177/000331970005100804. PY - 2000 SN - 0003-3197 (Print) 0003-3197 SP - S27-32 ST - Expanded polytetrafluoroethylene in external valvuloplasty for superficial or deep vein incompetence T2 - Angiology TI - Expanded polytetrafluoroethylene in external valvuloplasty for superficial or deep vein incompetence VL - 51 ID - 32 ER - TY - JOUR AB - Bovine thrombin has been used for more than 60 years as a surgical hemostat and sealant. Rare postsurgical events have been attributed to antibovine thrombin immunoglobulins cross-reacting with human homologs. In a literature review of 37 papers reporting safety outcomes in surgical patients, we extracted each paper for a quantitative measurement of bovine thrombin exposure and coagulopathic outcomes. We found that 59.5% of papers documented the commercial source of bovine thrombin and only 19% provided an estimate of exposure in units. Conventional tests for hypocoagulation were common (86%); however, only 9% of papers confirmed this inhibition as an isolated antibody. In addition, only 9% of papers cited a specific biomarker for thrombosis. © 2008 Expert Reviews Ltd. AD - Health Care Analytics Group, United BioSource Corporation, 101 Station Landing, Medford, MA, United States United BioSource Corporation, 101 Station Landing, Medford, MA, United States AU - Crean, S. M. AU - Michels, S. L. AU - Reynolds, M. W. DB - Scopus DO - 10.1586/14737159.8.5.651 IS - 5 KW - Adverse event Formulation Hemostasis Hemostat Iatrogenic immunization Surgery Thrombin M3 - Review N1 - Cited By :3 Export Date: 10 November 2020 PY - 2008 SP - 651-661 ST - Exogenous bovine thrombin as a biomarker of exposure and outcome T2 - Expert Review of Molecular Diagnostics TI - Exogenous bovine thrombin as a biomarker of exposure and outcome UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-51849133604&doi=10.1586%2f14737159.8.5.651&partnerID=40&md5=5892ad49d253d9221d330caa2a186255 VL - 8 ID - 1516 ER - TY - JOUR AB - This study aims to explore the probable mechanism of better result of dural reconstruction by CO2 laser soldering and the effect of exogenous basic fibroblast growth factor (bFGF) or transforming growth factor-beta1(TGFβ1) on wound healing. In part I of the study, ten minipigs were randomized into two equal groups, and the dural defects were reconstructed by conventional fibrin glue (FG) bonding (group I a) or by CO2 laser soldering (group Ib). In part II, 36 minipigs were randomized into three equal groups, and the dural defect was reconstructed by CO2 laser soldering; then exogenous bFGF or TGFβ1 was administered in group IIb and group II c, respectively, while group IIa served as control group. The dural specimens were harvested at 1st week postoperatively in part I; and at 1st, 2nd, 3rd, and 4th week postoperatively in part II, they were examined for healing condition and subjected to hematoxylin-eosin (HE) staining and immunohistochemical (IHC) staining with antibodies against bFGF and TGFβ1. In part I, group Ib showed higher fibroblast cell density than group Ia (P<0.05). The optical density (OD) for IHC staining with antibodies against bFGF of group Ib was significantly higher than that of group Ia (P<0.05), and for IHC staining with antibodies against TGFβ1, group Ib showed positive staining while group Ia was negative. In part II, administering exogenous bFGF or TGFβ1 made a left shift of fibroblast cell number-time curve compared with control group. For specimens' IHC staining with antibodies against bFGF, the OD of group IIb was higher than that of group IIa in the corresponding time. For specimens' IHC staining with antibodies against TGFβ1, the OD of groups IIb and IIc was both higher than that of group IIa (P<0.05 and P<0.01, respectively). In conclusion, CO 2 laser may trigger fibroblast proliferation through stimulating the secretion of bFGF and TGFβ1. Topically administering exogenous bFGF or TGFβ1 could accelerate the healing of the reconstructed dura by enhancing secretion of bFGF and/or TGFβ1 and promoting the process of fibroblast gathering-degrading. © 2013 Springer-Verlag. AD - Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 6 Xili, Tiantan, Dongcheng District, Beijing 100050, China Department of Interventional Neuroradiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China Beijing Neurosurgical Institute, Beijing 100050, China AU - Wang, Z. AU - Zhong, H. AU - Yang, Z. AU - Zhao, F. AU - Wang, B. AU - Qu, P. AU - Liu, P. DB - Scopus DO - 10.1007/s10103-013-1466-3 IS - 3 KW - Basic fibroblast growth factor Dura mater Porcine Reconstruction Soldering Transforming growth factor-beta1 Wound healing M3 - Article N1 - Export Date: 10 November 2020 PY - 2014 SP - 1165-1171 ST - Exogenous bFGF or TGFβ1 accelerates healing of reconstructed dura by CO2 laser soldering in minipigs T2 - Lasers in Medical Science TI - Exogenous bFGF or TGFβ1 accelerates healing of reconstructed dura by CO2 laser soldering in minipigs UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84902775383&doi=10.1007%2fs10103-013-1466-3&partnerID=40&md5=4f9f9d4cb23fa675ea6657f00de61713 VL - 29 ID - 1300 ER - TY - JOUR AD - Director of Infection Control, Downstate Medical Center, Brooklyn, NY AN - 106279422. Language: English. Entry Date: 20070511. Revision Date: 20150711. Publication Type: Journal Article AU - Allen, G. DB - ccm DP - EBSCOhost IS - 3 KW - Patient Safety Radio Frequency Identification Surgical Count Procedure Prospective Studies Surgical Patients N1 - abstract; commentary. Original Study: Macario A, Morris D, Morris S. Initial clinical evaluation of a handheld device for detecting retained surgical gauze sponges using radiofrequency identification technology. ARCH SURG 2006; 141: 659-662. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2007 SN - 0001-2092 SP - 638-639 ST - Evidence for practice. Radio frequency identification and surgical sponge detection T2 - AORN Journal TI - Evidence for practice. Radio frequency identification and surgical sponge detection UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106279422&site=ehost-live&scope=site VL - 85 ID - 854 ER - TY - JOUR AN - 106874103. Language: English. Entry Date: 20031010. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 7 KW - Foreign Bodies -- Prevention and Control Surgical Count Procedure Surgical Instruments Operating Room Personnel N1 - brief item. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2003 SN - 0190-5066 SP - 76-76 ST - Everyone counts -- or do they? Study results are troubling T2 - Same-Day Surgery TI - Everyone counts -- or do they? Study results are troubling UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106874103&site=ehost-live&scope=site VL - 27 ID - 938 ER - TY - JOUR AB - A 33-year-old male patient presented to clinic with a tender, discharging wound at mons pubis area. Three months before, he was a victim in a blast injury and received lifesaving emergency laparotomy at a field hospital in Baghdad, where shrapnel was removed from the abdomen and he was subsequently discharged. We present this unusual case of chronic wound from an undiscovered injury that was not formally explored at initial treatment, highlighting the importance of systematic exploration of all wounds particularly in sensitive body areas, despite cultural barriers both for the assessing clinicians and for the patients in that part of the world. AD - The Department of Plastic Surgery, The Royal Preston Hospital, Preston, UK. AN - 25214173 AU - Ramman, S. AU - Al-Rubayee, H. DA - Dec DO - 10.1111/iwj.12303 DP - NLM ET - 2014/09/13 IS - 6 KW - Abdominal Injuries/*complications/surgery *Abdominal Wall Adult Blast Injuries/*complications/surgery Chronic Disease Delayed Diagnosis Granuloma, Foreign-Body/*diagnosis/*etiology/surgery Humans Male Blast injury Foreign body reaction Granuloma Shrapnel LA - eng N1 - 1742-481x Ramman, Saif Al-Rubayee, Hassan Case Reports Journal Article England Int Wound J. 2014 Dec;11(6):579-80. doi: 10.1111/iwj.12303. Epub 2014 Sep 12. PY - 2014 SN - 1742-4801 SP - 579-80 ST - Every wound counts: a case of undiscovered wound in mons pubis resulting in a chronic foreign body granuloma of the abdominal wall T2 - Int Wound J TI - Every wound counts: a case of undiscovered wound in mons pubis resulting in a chronic foreign body granuloma of the abdominal wall VL - 11 ID - 155 ER - TY - JOUR AB - Foreign body ingestion represents a relatively common reason for gastroenterologist consultation. While over 80% of swallowed foreign bodies will ultimately pass uneventfully through the gastroin- testinal tract, 10-20% of cases will require endoscopic retrieval. We present an unusual case of foreign body ingestion involving a patient presenting with abdominal pain and melena. A 68 year-old man with a history of coronary artery disease presented to the hospital with a 3 day history of unremitting, burning epigastric pain associated with 1 episode of melenic stool. He denied hematochezia and weakness but did endorse a history of non-steroidal anti-inflammatory use. Upon admission he was found to be hemodynamically stable. Laboratory values including complete blood count, basic metabolic panel, and protime were unremarkable. Plain abdominal film on admission revealed an elongated radiopaque object concerning for foreign body in the antrum. The patient denied ingestion of any known non-food items. Upper endoscopy was performed. An elongated Forrest 2c 7mm x 2cm pyloric ulcer was discovered (figure 1). On retroflexion in the stomach, a quarter was visible in the greater curvature (figure 2). Closer inspection revealed a dime underneath the first coin (figure 3). Both coins were successfully retrieved with the Roth retrieval net. Biopsies for Helicobacter Pylori were negative. The patient was started on 40mg esomeprazole daily and was soon discharged with a plan for repeat upper endoscopy in 3 months. While the majority of ingestions can be managed with conservative measures, cases with airway compromise or peritoneal signs often call for urgent endoscopic or surgical evaluation. Concerning ingestions include sharp objects, disk batteries, magnets, or items with diameter greater than 25mm as they are less likely to pass through the pylorus. Ingestion of foreign non-food objects is more commonly encountered in the pediatric population with coins representing the majority of cases. When seen in adults, there is usually concomitant alcoholism or cognitive and psychiatric disorders. In our patient's case, there was a history of excessive alcohol abuse. It is likely that the coins were ingested while intoxicated. The patient's use of non-steroidal anti-inflammatory drugs likely lead to ulcer development; however, it is possible that the coins may also have contributed as ulcers have been reported with similar blunt objects. (Figure Presented). AD - J. Colizzo, University of South Florida Morsani, College of Medicine, Tampa, FL, United States AU - Colizzo, J. AU - Gill, J. DB - Embase DO - 10.1038/ajg.2016.394 KW - esomeprazole nonsteroid antiinflammatory agent abdominal pain adult adverse drug reaction aged airway alcohol abuse alcoholism biopsy blood cell count burn case report child cognitive defect coronary artery disease endoscopy epigastric pain foreign body Helicobacter pylori hospital human human tissue information retrieval ingestion magnet male melena nonhuman pylorus rectum hemorrhage side effect surgery ulcerogenesis weakness LA - English M3 - Conference Abstract N1 - L612869407 2016-11-10 PY - 2016 SN - 1572-0241 SP - S1323-S1324 ST - Every cent counts: A case of foreign body ingestion T2 - American Journal of Gastroenterology TI - Every cent counts: A case of foreign body ingestion UR - https://www.embase.com/search/results?subaction=viewrecord&id=L612869407&from=export http://dx.doi.org/10.1038/ajg.2016.394 VL - 111 ID - 393 ER - TY - JOUR AB - Purpose: To report a case of eventual corneal endothelial cell failure after spontaneous resolution of corneal edema after failed Descemet membrane endothelial keratoplasty (DMEK). Methods: Retrospective case report. Results: A 56-year-old man with Fuchs endothelial corneal dystrophy underwent cataract and DMEK surgery in the left eye. The transplanted DMEK graft detached in the early postoperative period and formed a peripheral scroll. Despite graft detachment, corneal edema resolved with endothelial cell repopulation of the central cornea. The patient's uncorrected visual acuity 5 months after surgery was 20/25. However, by 7 months after this spontaneous improvement, the patient started to complain of worsening vision. At 2.5 years, recurrent corneal edema became clinically apparent, and no endothelial cells were visible by specular microscopy in the central cornea. Conclusions: This case suggests that spontaneous healing of a large central Descemet membrane defect significantly diminishes the peripheral endothelial cell reserves and can lead to imminent bullous keratopathy. If there is any potential of corneal endothelial cells to regenerate after surgical removal of central Descemet membrane in Fuchs dystrophy, it is likely very limited. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. AD - Department of Ophthalmology, School of Medicine, Boston University, 85 E. Concord St, Boston, MA 02118, United States Department of Ophthalmology and Visual Sciences, School of Medicine, University of Maryland, Baltimore, MD, United States Department of Surgery, Baltimore VA Medical Center, VA Maryland Healthcare System, Baltimore, MD, United States AU - Lee, H. J. AU - Munir, W. M. DB - Scopus DO - 10.1097/ICO.0000000000001081 IS - 2 KW - corneal edema Descemet stripping descemetorhexis DMEK Fuchs' endothelial dystrophy M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2017 SP - 241-243 ST - Eventual Endothelial Failure after Initial Corneal Clearing after a Detached Endothelial Graft in Fuchs Dystrophy T2 - Cornea TI - Eventual Endothelial Failure after Initial Corneal Clearing after a Detached Endothelial Graft in Fuchs Dystrophy UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84995468839&doi=10.1097%2fICO.0000000000001081&partnerID=40&md5=bd842ae4db8c861fe40eb4d468b97565 VL - 36 ID - 1148 ER - TY - JOUR AB - NONE DECLARED Breast implants are medical devices that are used to augment breast size or to reconstruct the breast following mastectomy or to correct a congenital abnormality. Breast implants consist of a silicone outer shell and a filler (most commonly silicone gel or saline). Approximately 5 to 10 million women worldwide have breast implants. Histomorphometric study to evaluate the biological tissue compatibility of silicone implants suitable for plastic surgery and the adverse effects and risks of this material. Thirty Wistar white rats received subcutaneous implants and the revestiment of silicone gel Silimed ®®, and randomized into six groups of five animals each, according to the type of implanted material and the time of sacrifice. Eight areas of 60.11mm2 corresponding to the obtained surgical pieces were analyzed, counting mesenchymal cells, eosinophils, and foreign body giant cells, observing an acceptable biocompatibility in all implants, for subsequent statistical analysis by Tukey test. Silicone gel showed inflammation slightly greater than for other groups, with tissue reactions varying from light to moderate, whose result was the formation of a fibrous capsule around the material, recognized by the organism as a foreign body. Despite frequent local complications and adverse outcomes, this research showed that the silicone and top layer presented an acceptable chronic inflammatory reaction, which did not significantly differ from the control group. In general, it is possible to affirm that silicone gel had acceptable levels of biocompatibility, confirmed the rare presence of foreign body giant cells, and when of the rupture, formed a fibrous capsule around the material, separating the material of the organism. AD - Pediatric Dentistry, Araçatuba School of Dentistry , Unesp, Stomatologist of CEOPE - State Center of Dentistry for Patients with Special Needs, Department of Univag- Academic Center/Várzea Grande/MT/Brazil. AN - 24039333 AU - França, D. C. AU - de Castro, A. L. AU - Soubhia, A. M. AU - de Aguiar, S. M. AU - Goiato, M. C. C2 - PMC3766542 DO - 10.5455/aim.2013.21.93-97 DP - NLM ET - 2013/09/17 IS - 2 KW - Breast Implantation Materials Testing Rats Silicone Gels Wistar LA - eng N1 - 1986-5988 França, Diurianne Caroline Campos de Castro, Alvimar Lima Soubhia, Ana Maria Pires de Aguiar, Sandra Maria Herondina Coelho Ávila Goiato, Marcelo Coelho Journal Article Acta Inform Med. 2013;21(2):93-7. doi: 10.5455/aim.2013.21.93-97. PY - 2013 SN - 0353-8109 (Print) 0353-8109 SP - 93-7 ST - Evaluation of the biocompatibility of silicone gel implants - histomorphometric study T2 - Acta Inform Med TI - Evaluation of the biocompatibility of silicone gel implants - histomorphometric study VL - 21 ID - 142 ER - TY - JOUR AB - Objective To test performance of SurgiSafe®, a radiofrequency electronic device to detect surgical textiles during operations as compared to manual counting. Methods Surgical sponges with radiofrequency TAGs were placed in the abdominal cavity of a pig submitted to laparotomy, in randomly distributed sites. The TAGs were counted manually and also using SurgiSafe®. Positive and negative predictive values, sensitivity, specificity and time required for counting were analyzed for both methods. Results Through the analysis of 35 surgical cycles, SurgiSafe® immediately identified all sponges, with specificity, sensitivity, positive and negative predictive values of 100%. Although not statistically significant, the manual count had sensitivity of 99.72% and specificity of 99.90%. Conclusion SurgiSafe® proved to be an effective device to identify surgical sponges in vivo, in real time; and its use as an adjuvant to manual counting is very helpful to increase patient's safety. AD - Centro de Experimentação e Treinamento, Hospital Israelita Albert Einstein, SPSão Paulo, Brazil AU - Antonio, A. M. AU - Vieira, C. A. P. DB - Scopus DO - 10.1590/s1679-45082018ao3997 IS - 1 M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 SP - eAO3997 ST - Evaluation of radiofrequency electronic system in intraoperative monitoring of surgical textiles T2 - Einstein (Sao Paulo, Brazil) TI - Evaluation of radiofrequency electronic system in intraoperative monitoring of surgical textiles UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047735758&doi=10.1590%2fs1679-45082018ao3997&partnerID=40&md5=319f247d42e940579cda30250f76b7af VL - 16 ID - 1094 ER - TY - JOUR AB - Irrigation under pressure of contaminated surgical wounds causes the elimination of bacteria and foreign bodies from the wound. The Pulsating-Jet as an irrigation device, especially under high pressure, represents a useful method for the prevention of wound infections. In this study, the authors evaluate the results in 95 patients with purulent peritonitis who were subdivided in four groups: (a) Control, (b) Manual irrigation, (c) Pressure irrigation at 50 lbs/square inch, (d) Pressure irrigation at 70 lbs/square inch. In groups b, c, and d, semiquantitative evaluation of bacterial contamination was done before and after irrigation. The evaluation of the results was based on the percentage decrease in the bacterial counts after irrigation, the severity of the wound infection and the patients' morbidity understood as number of postoperative hospital days. The results show, with statistical significance, that manual irrigation is not effective when compared to Pulsating-Jet irrigation, especially at high pressures. The usage of of this irrigating method at high pressures and flows entails a reduction of the bacterial count and of the surgical wound infection rate and thus, shortens the postoperative hospital stay. AD - Residencia Sanitaria 'Ntra Sra de Aranzazu', Department of Surgery, San Sebastian AU - Lopez, V. AU - Yague Perez, S. AU - Llamas Zuniga, P. AU - Perez Trallero, E. DB - Embase IS - 3-4 KW - abdominal lavage clinical article diagnosis human infection prevention lavage peritoneum purulent peritonitis therapy wound wound infection LA - English N1 - L14129746 1984-06-06 PY - 1984 SP - 34-38 ST - Evaluation of Pulsating Jet lavage in prevention of surgical wound infection T2 - Journal of Abdominal Surgery TI - Evaluation of Pulsating Jet lavage in prevention of surgical wound infection UR - https://www.embase.com/search/results?subaction=viewrecord&id=L14129746&from=export VL - 26 ID - 677 ER - TY - JOUR AB - Introduction: Patient safety in Operation theatre is one of the greatest challenges in Health care. Ensuring patient safety in operating room begins as the patient enters the operation theatre and includes attention to all applicable types of preventable medical faults (including, for example medication mistakes), so that surgical errors should be rare to this environment. Steps to avoid wrong-site, wrong-person, wrong-procedure errors, or retained foreign objects unchecked blood transfusions, mismatched organ transplantation and un-noticed allergies have been recommended, it should start with a structured communication between the patient, the surgeon(s), and other health care team members. Prevention of surgical errors requires the watchfulness of all personnel involved in the patient's care. Objective: The aim of this current study is to improve patient safety in operation room. Method: Descriptive study design was used. This study was conducted in six months in Main Operation Theatre Children Hospital and Institute of Child Health Lahore. 288 Patients were analysed in Main Operation theatre, which were selected through convenient sampling technique. Their age ranges from 1to 14 years. WHO Surgical Safety Checklist was used to evaluate patient safety in surgical block. Results: There were 288 patients analysed in the operating room block, for surgical management, to improve patient safety. Each step of standard surgical safety checklist was observed and filled. Checklist is divided into three steps before induction on anaesthesia, start of surgical intervention and before any team member leaves operating room. 96.9% consent forms, 96.6% patient identity site procedures confirmed, 75.3% surgical site marked, 88.9% anaesthesia machine and medication check complete, 8.7% patient have known allergy, 0% patient have difficult airway aspiration rate, 41.3% risk of >500ml blood loss, 28.8% team members introduced themselves, 95.5% patient name, 96.6% procedure site position planned, 61.8% if blood loss is anticipated, arranged and matched, 52.1% specific equipment required, 5.9% critical or unexpected steps. 23.3% patients specific concerns, 93.1% monitoring equipment e. g. blood, 86.8% sterility of instruments confirmed, 23% are there equipment issues or concerns, 99.7% surgical site bundle undertaken, 100% antibiotic prophylaxis, 29% patient warming, 22.2% hair removal, 100% glycemic control, 0% VTE prophylaxis, 86.1% essential imaging undertaken, 98.6% has name of procedure recorded, 99% has it confirmed instruments swabs counts complete, 93.1% specimen been labelled,10.1% have any equipment problems been identified that need to be addressed. AD - S. Naseem AU - Naseem, S. AU - Saleem, M. DB - Embase IS - 1 KW - airway allergy anesthesia gas machine antibiotic prophylaxis aspiration bleeding checklist clinical evaluation conference abstract female glycemic control hair removal human human tissue identity infant informed consent major clinical study male monitoring operating room patient safety pediatric hospital plant leaf prevention sampling study design surgery surgical error warming LA - English M3 - Conference Abstract N1 - L621582323 2018-04-12 PY - 2018 SN - 0304-4904 SP - 52-53 ST - Evaluation of patient safety checklist in surgical block in CH & ICH Lahore T2 - Pakistan Paediatric Journal TI - Evaluation of patient safety checklist in surgical block in CH & ICH Lahore UR - https://www.embase.com/search/results?subaction=viewrecord&id=L621582323&from=export VL - 42 ID - 351 ER - TY - JOUR AB - Combinations of linezolid (LZD) or trimethoprim/sulfamethoxazole (SXT) plus rifampicin (RIF) are alternative oral treatments for staphylococcal prosthetic joint infections (PJIs) when fluoroquinolones are not possible to use, but there is limited evidence regarding their activity. This study evaluated the efficacy of LZD and SXT, alone and in combination with RIF, against Staphylococcus aureus in an in vitro pharmacokinetic/pharmacodynamic biofilm model. Using the CDC Biofilm Reactor(®) system, simulated regimens of LZD (600 mg every 12 h), SXT (160/800 mg every 8 h) and levofloxacin (LVX) (750 mg/day), alone and in combination with RIF (600 mg/day), were evaluated against one methicillin-susceptible S. aureus (MSSA) and one methicillin-resistant S. aureus (MRSA) strain. Antibiotic efficacy was evaluated by the decrease in planktonic bacterial counts from medium and biofilm-embedded bacteria from coupons over 56 h. Resistant strains were screened. In both strains, SXT alone was ineffective and LZD presented low activity, but no resistance emerged. Combinations with RIF significantly increased the antibiofilm efficacy against MSSA (Δlog CFU/mL 56h-0h: SXT + RIF, -2.9 and LZD + RIF, -3.1), but RIF-resistant strains appeared with SXT + RIF. Against MRSA, LZD + RIF (-3.1) protected against the emergence of resistance and was more effective than SXT + RIF (-0.6; P <0.05), in which RIF-resistant strains were again detected. LVX + RIF confirmed its high efficacy against biofilm-embedded bacteria, this being the most effective therapy (-5.1 against MSSA). The emergence of RIF-resistant strains with SXT + RIF poses serious concerns for its use in clinical practice. Interestingly, LZD + RIF appears to be an appropriate alternative for PJI caused by LVX-resistant S. aureus. AD - Laboratory of Experimental Infection, Infectious Diseases Service, IDIBELL-Hospital Universitari Bellvitge, University of Barcelona, Feixa Llarga, s/n, 08907, L'Hospitalet de Llobregat, Barcelona, Spain. Laboratory of Experimental Infection, Infectious Diseases Service, IDIBELL-Hospital Universitari Bellvitge, University of Barcelona, Feixa Llarga, s/n, 08907, L'Hospitalet de Llobregat, Barcelona, Spain; Spanish Network for the Research in Infectious Diseases (REIPIRD12/0015), Instituto de Salud Carlos III, Madrid, Spain. Electronic address: omurillo@bellvitgehospital.cat. Nephrology Service and Laboratory of Experimental Nephrology, University of Barcelona, Campus Bellvitge, Pavelló de Govern, Feixa Llarga, s/n, 08907, L'Hospitalet de Llobregat, Barcelona, Spain. Department of Microbiology, IDIBELL-Hospital Universitari Bellvitge, Barcelona, Spain; Department of Microbiology, CIBERES ISCIII, Madrid, Spain. Laboratory of Experimental Infection, Infectious Diseases Service, IDIBELL-Hospital Universitari Bellvitge, University of Barcelona, Feixa Llarga, s/n, 08907, L'Hospitalet de Llobregat, Barcelona, Spain; Spanish Network for the Research in Infectious Diseases (REIPIRD12/0015), Instituto de Salud Carlos III, Madrid, Spain. AN - 29374577 AU - El Haj, C. AU - Murillo, O. AU - Ribera, A. AU - Lloberas, N. AU - Gómez-Junyent, J. AU - Tubau, F. AU - Fontova, P. AU - Cabellos, C. AU - Ariza, J. DA - Jun DO - 10.1016/j.ijantimicag.2018.01.014 DP - NLM ET - 2018/01/29 IS - 6 KW - Anti-Bacterial Agents/*pharmacology Biofilms/drug effects/*growth & development Drug Combinations Humans Linezolid/*pharmacology Methicillin-Resistant Staphylococcus aureus/*drug effects/isolation & purification Microbial Sensitivity Tests Prosthesis-Related Infections/drug therapy/microbiology Rifampin/*pharmacology Sulfamethizole/*pharmacology Trimethoprim/*pharmacology Biofilm Cotrimoxazole Foreign-body infection Rifampicin combinations Staphylococcus aureus Trimethoprim/sulfamethoxazole LA - eng N1 - 1872-7913 El Haj, Cristina Murillo, Oscar Ribera, Alba Lloberas, Nuria Gómez-Junyent, Joan Tubau, Fe Fontova, Pere Cabellos, Carme Ariza, Javier Journal Article Netherlands Int J Antimicrob Agents. 2018 Jun;51(6):854-861. doi: 10.1016/j.ijantimicag.2018.01.014. Epub 2018 Jan 31. PY - 2018 SN - 0924-8579 SP - 854-861 ST - Evaluation of linezolid or trimethoprim/sulfamethoxazole in combination with rifampicin as alternative oral treatments based on an in vitro pharmacodynamic model of staphylococcal biofilm T2 - Int J Antimicrob Agents TI - Evaluation of linezolid or trimethoprim/sulfamethoxazole in combination with rifampicin as alternative oral treatments based on an in vitro pharmacodynamic model of staphylococcal biofilm VL - 51 ID - 206 ER - TY - JOUR AB - Objectives: To evaluate factors that could be associated with retained surgical sponges in veterinary patients. Materials and Methods: A survey was distributed to 322 veterinarians attending a national veterinary conference in the UK. The survey included questions about the staff, scheduling, type of surgical procedure, surgical sponges, methods to track surgical sponges and details of clinical cases with retained surgical sponges. Results: The response rate was 64 of 322 (19%). Lack of designated scheduled time for surgical procedures was reported by 30% of respondents and was variable for 31%. More than half of respondents (66%) had two people involved in each surgical procedure. The majority of respondents sterilised their own surgical sponges (91%) and used non-radiopaque surgical sponges (56%). Sponges were not counted by 27% of respondents and only occasionally by 20%. Sponge count was not recorded by 70% of respondents. The majority (66%) did not use or have a surgical checklist. Lack of awareness of gossypibomas was reported by 11% of respondents. In all, 27% of respondents were aware of at least one case of retained surgical sponge. Of the 17 cases reported, 14 were small animals. The abdomen was the most common anatomical location for retained surgical sponges and followed elective neutering. Clinical Significance: Despite the low-response rate, our results suggest that methods of surveillance might reduce the incidence of retained surgical sponges. Lack of specifically scheduled time for surgery, few theatre staff and lack of sponge counting and documentation may have contributed to the 17 retained surgical sponge cases reported. AD - F.R. Rodriguez, Department of Small Animal Surgery, Animal Bluecare Hospital, A7 Km 204, Mijas Costa, Malaga, Spain AU - Rodriguez, F. R. AU - Kirby, B. M. AU - Ryan, J. DB - Embase Medline DO - 10.1111/jsap.12873 IS - 9 KW - operating room surgical sponge abdominal pain abdominal surgery article cat dog donkey end to end anastomosis gossypiboma health survey herniorrhaphy horse human hysterectomy instrument sterilization intestine resection medical error nonhuman patient safety postoperative complication pyometra radiography retained surgical sponge risk factor surgical technique veterinarian LA - English M3 - Article N1 - L623215070 2018-07-31 2018-09-13 PY - 2018 SN - 1748-5827 0022-4510 SP - 570-577 ST - Evaluation of factors associated with retained surgical sponges in veterinary patients: a survey of veterinary practitioners T2 - Journal of Small Animal Practice TI - Evaluation of factors associated with retained surgical sponges in veterinary patients: a survey of veterinary practitioners UR - https://www.embase.com/search/results?subaction=viewrecord&id=L623215070&from=export http://dx.doi.org/10.1111/jsap.12873 VL - 59 ID - 334 ER - TY - JOUR AB - BACKGROUND: Foreign body aspiration (FBA) in infants and young children is a common and potentially life-threatening event. Although studies have extensively described the signs and symptoms of suspected FBA (sFBA), only few systematically compared their value for predicting bronchoscopy results. OBJECTIVES: The objectives of this study were to describe the clinical and radiologic signs and symptoms of sFBA and to identify predictors of bronchoscopically proven FBA (pFBA). SETTING: This study was conducted at a referral tertiary university hospital with an outpatient clinic and a 90-bed pediatric unit. METHODS: Signs and symptoms were retrospectively analyzed for all children who had received bronchoscopy between July 1992 and April 2000 because of sFBA. Radiologic signs of FBA were reviewed and scored by 2 independent radiologists. RESULTS: One hundred sixty children (mean age, 2.8 years; range, 11 months to 16.8 years) were enrolled in the study. Foreign body aspiration, mostly affecting the right main bronchus, was proven bronchoscopically in 122 (76%) of these children. Independent predictors of pFBA in multivariable analyses were focal hyperinflation on chest radiograph (beta = 45.4; 95% confidence interval [CI] = 5.3-390.5; P = .001), witnessed choking crisis (beta = 18.6; 95% CI = 4.7-73.0; P < .001), and white blood cell count greater than 10,000/muL (beta = 4.2; 95% CI = 1.2-14.7; P = .026). The cumulative proportion of pFBA cases increased with the number of risk factors (0, 16%; 1, 47%; 2, 96%; 3, 100%). CONCLUSIONS: Clinical judgment to perform bronchoscopy for sFBA was correct in 76% of the children investigated. Focal hyperinflation, witnessed choking crisis, and elevated white blood cell count were strongly associated with pFBA; bronchoscopy can be strongly recommended in the presence of at least 2 risk factors when FBA is suspected. AD - Institute of Diagnostic Radiology, Interventional Radiology, and Nuclear Medicine, BG Clinics Bergmannsheil, Ruhr-University of Bochum, D-44789 Bochum, Germany. christoph.heyer@rub.de AN - 17101364 AU - Heyer, C. M. AU - Bollmeier, M. E. AU - Rossler, L. AU - Nuesslein, T. G. AU - Stephan, V. AU - Bauer, T. T. AU - Rieger, C. H. DA - Nov DO - 10.1016/j.jpedsurg.2006.06.016 DP - NLM ET - 2006/11/15 IS - 11 KW - Adolescent *Bronchi *Bronchoscopy Child Child, Preschool Female Foreign Bodies/*diagnosis/*surgery Humans Infant Male Predictive Value of Tests *Respiratory Aspiration/diagnosis/surgery Retrospective Studies LA - eng N1 - 1531-5037 Heyer, Christoph M Bollmeier, Melanie E Rossler, Leo Nuesslein, Thomas G Stephan, Volker Bauer, Torsten T Rieger, Christian H L Journal Article United States J Pediatr Surg. 2006 Nov;41(11):1882-8. doi: 10.1016/j.jpedsurg.2006.06.016. PY - 2006 SN - 0022-3468 SP - 1882-8 ST - Evaluation of clinical, radiologic, and laboratory prebronchoscopy findings in children with suspected foreign body aspiration T2 - J Pediatr Surg TI - Evaluation of clinical, radiologic, and laboratory prebronchoscopy findings in children with suspected foreign body aspiration VL - 41 ID - 63 ER - TY - JOUR AB - Purpose: To assess the biocompatibility of intraocular lens (IOL) material by studying the number of cells adhering to IOLs in monkey eyes. Setting: Department of Ophthalmology, Kyushu University, Fukuoka, Japan. Methods: Silicone or poly(methyl methacrylate) (PMMA) IOL implantation was performed in 21 monkeys. One eye of each animal had surgery. The IOL-implanted eyes were enucleated 1, 2, 3, 5, and 7 days and 1, 3, 4, 5, and 9 months after the procedure. One eye was studied at each time. Cells on the anterior IOL surface were photographed using a scanning electron microscope, counted and assessed with NEC, Graphtec, and Nikon equipment, and then observed using a transmission electron microscope. Results: Leukocytes, macrophages, and giant cells were found on the anterior IOL surface. Numerous cells were observed on the PMMA IOLs in the early postoperative period; they gradually decreased. Few cells were seen on the silicone IOLs during the course of the study. The giant cells became larger during the postoperative period. Conclusion: The foreign-body reaction to silicone IOLs in monkey eyes was less than that to PMMA IOLs. © 2001 ASCRS and ESCRS. AD - Department of Ophthalmology, Wakayama Medical University, Kimiidera 811-1, Wakayama 641-8509, Japan Department of Ophthalmology, Wakayama Medical University, Wakayama, Japan Department of Ophthalmology, Kyushu University, Fukuoka, Japan AU - Ohnishi, Y. AU - Yoshitomi, T. AU - Sakamoto, T. AU - Fujisawa, K. AU - Ishibashi, T. DB - Scopus DO - 10.1016/S0886-3350(01)00961-0 IS - 12 M3 - Article N1 - Cited By :16 Export Date: 10 November 2020 PY - 2001 SP - 2036-2040 ST - Evaluation of cellular adhesions on silicone and poly(methyl methacrylate) intraocular lenses in monkey eyes: An electron microscopic study T2 - Journal of Cataract and Refractive Surgery TI - Evaluation of cellular adhesions on silicone and poly(methyl methacrylate) intraocular lenses in monkey eyes: An electron microscopic study UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035205740&doi=10.1016%2fS0886-3350%2801%2900961-0&partnerID=40&md5=2ee206209faccf24327d3e8a89b1d8a9 VL - 27 ID - 1665 ER - TY - JOUR AB - Surgical sponge counting is an essential patient safety measure in the OR in which all members of the surgical team must participate. The RN acting as circulator is responsible for accurately documenting sponge counts during the surgical procedure. A sequentially numbered sponge product was evaluated in a survey of OR personnel to determine ease of use and whether the product affected the flow of the surgical procedure. Survey respondents reported that the numbered sponge product was easy to use and did not lengthen or affect the flow of the surgical procedure. Respondents also indicated that the product may contribute to patient safety. AD - Renown Health, Reno, Nevada, USA. AN - 17499056 AU - Pelter, M. M. AU - Stephens, K. E. AU - Loranger, D. DA - May DO - 10.1016/j.aorn.2007.04.010 DP - NLM ET - 2007/05/15 IS - 5 KW - Foreign Bodies/*prevention & control Humans Operating Room Nursing/methods Operating Rooms/standards Safety Management/methods/standards Surgical Sponges/*statistics & numerical data LA - eng N1 - Pelter, Michele M Stephens, Kimberly E Loranger, Denise Evaluation Study Journal Article Research Support, Non-U.S. Gov't United States AORN J. 2007 May;85(5):931-6, 938-40. doi: 10.1016/j.aorn.2007.04.010. PY - 2007 SN - 0001-2092 (Print) 0001-2092 SP - 931-6, 938-40 ST - An evaluation of a numbered surgical sponge product T2 - Aorn j TI - An evaluation of a numbered surgical sponge product VL - 85 ID - 65 ER - TY - JOUR AB - BACKGROUND: Retained surgical instruments (RSI) are one of the most serious preventable complications in operating room settings, potentially leading to profound adverse effects for patients, as well as costly legal and financial consequences for hospitals. Safety measures to eliminate RSIs have been widely adopted in the United States and abroad, but despite widespread efforts, medical errors with RSI have not been eliminated. OBJECTIVE: Through a systematic review of recent studies, we aimed to identify the impact of radio frequency identification (RFID) technology on reducing RSI errors and improving patient safety. METHODS: A literature search on the effects of RFID technology on RSI error reduction was conducted in PubMed and CINAHL (2000-2016). Relevant articles were selected and reviewed by 4 researchers. RESULTS: After the literature search, 385 articles were identified and the full texts of the 88 articles were assessed for eligibility. Of these, 5 articles were included to evaluate the benefits and drawbacks of using RFID for preventing RSI-related errors. The use of RFID resulted in rapid detection of RSI through body tissue with high accuracy rates, reducing risk of counting errors and improving workflow. CONCLUSIONS: Based on the existing literature, RFID technology seems to have the potential to substantially improve patient safety by reducing RSI errors, although the body of evidence is currently limited. Better designed research studies are needed to get a clear understanding of this domain and to find new opportunities to use this technology and improve patient safety. AD - From the *Division of General Internal Medicine and Primary Care, Brigham and Women's Hospital; †Center for Patient Safety, Brigham and Women's Hospital and Harvard Medical School; ‡Bouve' School of Health Sciences, School of Nursing, Northeastern University; and §Medical Library and Educational Services, Brigham and Women's Hospital, Boston, Massachusetts. AN - 28230583 AU - Schnock, K. O. AU - Biggs, B. AU - Fladger, A. AU - Bates, D. W. AU - Rozenblum, R. DA - Feb 22 DO - 10.1097/pts.0000000000000365 DP - NLM ET - 2017/02/24 LA - eng N1 - 1549-8425 Schnock, Kumiko O Biggs, Bonnie Fladger, Anne Bates, David W Rozenblum, Ronen Journal Article United States J Patient Saf. 2017 Feb 22. doi: 10.1097/PTS.0000000000000365. PY - 2017 SN - 1549-8417 ST - Evaluating the Impact of Radio Frequency Identification Retained Surgical Instruments Tracking on Patient Safety: Literature Review T2 - J Patient Saf TI - Evaluating the Impact of Radio Frequency Identification Retained Surgical Instruments Tracking on Patient Safety: Literature Review ID - 191 ER - TY - JOUR AB - PURPOSE: Percutaneous endoscopic gastrostomy (PEG) enables enteral nutrition for patients with inadequate oral intake. Laparoscopic guidance of PEG insertion is used for high-risk populations, including in infants less than 5kg at insertion. This study aimed to assess complication rates with traditional PEG tube insertion in infants less than 5kg at a single tertiary care center. METHODS: A retrospective review of patients less than 5kg who underwent PEG insertion was conducted. PEG insertion-related complications, up to four years following insertion, were collected. Outcomes were reported as counts and percentages, or median with minimum and maximum values. RESULTS: 480 pediatric gastrostomy procedures between January 1, 2009 and February 1, 2017, were screened, with 129 included for analysis. Median weight at PEG insertion was 3800g. Superficial surgical site infection (SSI) occurred in 6 (4.7%) patients, and 1 (0.8%) required readmission for intravenous antibiotics. One (0.8%) required endoscopic management for retained foreign body, 1 (0.8%) required operative management for gastrocolic fistula, and 1 (0.8%) for persistent gastrocutaneous fistula. No deep space SSI, procedure-related hemorrhage requiring readmission or transfusion, buried bumper syndrome, or procedure-related mortality occurred. CONCLUSION: Traditional PEG tube insertion in infants less than 5kg results in complication rates comparable to pediatric literature standards. LEVEL OF EVIDENCE: Level II, retrospective prognosis study. AD - McMaster Children's Hospital, Hamilton, Ontario, Canada. McMaster Pediatric Surgery Research Collaborative, Department of Surgery, McMaster University, Hamilton, Ontario, Canada. McMaster Children's Hospital, Hamilton, Ontario, Canada; McMaster Pediatric Surgery Research Collaborative, Department of Surgery, McMaster University, Hamilton, Ontario, Canada. Electronic address: waltonj@mcmaster.ca. AN - 29506815 AU - Fernandes, A. R. AU - Elliott, T. AU - McInnis, C. AU - Easterbrook, B. AU - Walton, J. M. DA - May DO - 10.1016/j.jpedsurg.2018.02.017 DP - NLM ET - 2018/03/07 IS - 5 KW - *Body Weight Enteral Nutrition/*methods Female Gastroscopy/*methods Gastrostomy/*adverse effects Humans Incidence Infant Infant, Newborn Male Ontario/epidemiology Postoperative Complications/*epidemiology/therapy Retrospective Studies Treatment Outcome Complications Laparoscopic Neonate Percutaneous endoscopic gastrostomy Pull technique LA - eng N1 - 1531-5037 Fernandes, Alisha R Elliott, Tessa McInnis, Carter Easterbrook, Bethany Walton, J Mark Journal Article United States J Pediatr Surg. 2018 May;53(5):933-936. doi: 10.1016/j.jpedsurg.2018.02.017. Epub 2018 Feb 8. PY - 2018 SN - 0022-3468 SP - 933-936 ST - Evaluating complication rates and outcomes among infants less than 5kg undergoing traditional percutaneous endoscopic gastrostomy insertion: A retrospective chart review T2 - J Pediatr Surg TI - Evaluating complication rates and outcomes among infants less than 5kg undergoing traditional percutaneous endoscopic gastrostomy insertion: A retrospective chart review VL - 53 ID - 209 ER - TY - JOUR AB - The purpose of this study was to evaluate various types of meniscus scaffolds that mimic the meniscus structure, and to establish a novel cell-free meniscus scaffold with polyglycolic acid or poly-l-lactic acid. Four types of scaffolds were implanted into Japanese white rabbits: poly-l-lactic acid sponge poly-l-lactic acid, PGA-coated PLLA sponge, PGA lamination, and film-coated PGA lamination. Samples were harvested at 8 and 12 weeks after implantation, and a compression stress test was performed. The meniscus size and Ishida scores were evaluated for regenerated tissue. Immunohistochemistry was analyzed by anti-type I, II and X collagen antibodies to investigate the structure of the regenerated tissue, and by anti-iNOS antibody to investigate the inflammatory tissue of the meniscus. The cell nuclei of lymphocytes and foreign body multinucleated giant cells were counted in hematoxylin and eosin staining. Modified Mankin scores for cartilage degeneration were used for assessment after Safranin-O/Fast Green staining. The biomechanical test showed that l- and film-coated PGA lamination exhibited greater strength than s- and PGA-coated PLLA sponge. At 12 weeks, the size of meniscus and the Ishida score in implanted film-coated PGA lamination were improved significantly compared with the defect groups. The type II collagen staining intensity in the PGA lamination lamination is significantly higher than the defect at eight weeks. The staining intensity of iNOS and number of lymphocytes significantly increased in sponge poly-l-lactic acid at eight weeks, and increased in p-PLLA at 12 weeks. Foreign body multinucleated giant cells in implantation groups appeared, especially at eight weeks. The Mankin score for film-coated PGA lamination was significantly lower than for the defect at 12 weeks. Novel meniscal scaffolds especially PGA should possess not only biological but also biomechanical functions. In conclusions, film-coated PGA lamination was the beneficial property for meniscus scaffold from the points of better biomechanical function, good regeneration, and less inflammation with chondroprotective effects. © The Author(s) 2017. AD - Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka, 569-8686, Japan QOL Research Center Laboratory, Gunze Limited, Kyoto, Japan AU - Murakami, T. AU - Otsuki, S. AU - Nakagawa, K. AU - Okamoto, Y. AU - Inoue, T. AU - Sakamoto, Y. AU - Sato, H. AU - Neo, M. DB - Scopus DO - 10.1177/0885328217713631 IS - 2 KW - Meniscectomy meniscus repair meniscus scaffold poly- l -lactic acid polyglycolic acid M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2017 SP - 150-161 ST - Establishment of novel meniscal scaffold structures using polyglycolic and poly- l -lactic acids T2 - Journal of Biomaterials Applications TI - Establishment of novel meniscal scaffold structures using polyglycolic and poly- l -lactic acids UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85025466435&doi=10.1177%2f0885328217713631&partnerID=40&md5=1966aa446aa1364a8b369edebb29096d VL - 32 ID - 1127 ER - TY - JOUR AB - Introduction: Here we present our clinical experience in a case of esophagus perforation due to the swallowing of a bone piece causing acute angina pectoris and leading to misdiagnosis of acute coronary syndrome. Case presentation: A 73-year-old Caucasian man underwent urgent coronary angiography with possible diagnosis of acute coronary syndrome. His coronary arteries were found to be normal. A computed tomography examination revealed esophagus perforation by a foreign body (a piece of bone), and he underwent urgent left thoracotomy and the foreign body was removed. Conclusions: Sometimes, even a piece of bone within a meal can lead to esophagus perforation, and injure the pericardium and myocardium. The symptoms of esophagus perforation may be confused with acute coronary syndrome due to their similarities and lack of knowledge about the detailed clinical history as shown in our case. Thus, careful consideration of detailed clinical history as well as choosing an appropriate medical imaging modality, such as computed tomography, should always be kept in mind in order to promptly diagnose and start early treatment to reduce mortality. © 2015 Erdal et al.; licensee BioMed Central. AD - Department of General Surgery, Transplantation Center, Sanko University Hospital, Gaziantep, Turkey Sanko University Hospital, Department of Emergency, Gaziantep, Turkey Uludag University School of Medicine, Department of General Surgery, Bursa, Turkey Department of Radiology, Sanko University Hospital Gaziantep, Gaziantep, Turkey Sanko University Hospital, Department of Thoracic Surgery, Gaziantep, Turkey Department of General Surgery, Sanko University Hospital, Gaziantep, Turkey AU - Erdal, U. AU - Mehmet, D. AU - Turkay, K. AU - Mehmet, I. A. AU - Ibrahim, N. AU - Hasan, B. C7 - 57 DB - Scopus DO - 10.1186/s13256-015-0532-9 IS - 1 KW - Acute coronary syndrome Esophagus perforation Foreign body M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2015 ST - Esophagus perforation and myocardial penetration caused by swallowing of a foreign body leading to a misdiagnosis of acute coronary syndrome: A case report T2 - Journal of Medical Case Reports TI - Esophagus perforation and myocardial penetration caused by swallowing of a foreign body leading to a misdiagnosis of acute coronary syndrome: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84928737125&doi=10.1186%2fs13256-015-0532-9&partnerID=40&md5=74a21f3a780ebcd3a497803ccd86e1eb VL - 9 ID - 1231 ER - TY - JOUR AB - Esophageal perforation is a serious condition with a high mortality rate. Delayed detection of esophageal perforation may result in devastating complications such as mediastinitis and pericarditis. Esophageal perforation is rarely due to aspiration of foreign bodies. Here we report the case of a 59-year-old male patient with complicated esophageal perforation due to ingestion of a chicken bone, whose first signs are considered to be acute non-specific pericarditis. © 2014 Turkish Society of Cardiology. AD - Department of Cardiology, Rize State Hospital, Konak Evler, No: 17, Rize, 53100, Turkey Department of Cardiology, Erzincan University, Faculty of Medicine, Erzincan, Turkey Department of Cardiology, Recep Tayyip Erdoʇan University, Faculty of Medicine, Rize, Turkey AU - Duman, H. AU - Bakirci, E. M. AU - Karadaʇ, Z. AU - Uʇurlu, Y. DB - Scopus DO - 10.5543/tkda.2014.26350 IS - 7 KW - Esophageal perforation Pericarditis M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2014 SP - 658-661 ST - Esophageal rupture complicated by acute pericarditis T2 - Turk Kardiyoloji Dernegi Arsivi TI - Esophageal rupture complicated by acute pericarditis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84931087174&doi=10.5543%2ftkda.2014.26350&partnerID=40&md5=d1be20bb309c1eed1c4aa3ce54d781b9 VL - 42 ID - 1279 ER - TY - JOUR AB - A 73-year-old woman complaining of sudden hoarseness visited our hospital 17 days after the onset. The upper gastrointestinal contrast study showed a shallow ulcer crater with moderate bulging in the upper thoracic esophagus. Endoscope and computed tomography revealed an esophageal foreign body, a Press Through Pack (PTP), in the esophageal ulcer. The PTP could be removed endoscopically. Two months after extraction of the PTP, the patient was taking normal food orally and was discharged. The esophageal perforation, looking like a diverticle, was still present more than 1 year after the onset. AD - Department of Surgery, Kurume University, School of Medicine, 67 Asahi-machi, Kurume-City, Fukuoka 830-0011, Japan AU - Sudo, T. AU - Sueyoshi, S. AU - Fujita, H. AU - Yamana, H. AU - Shirouzu, K. DB - Scopus DO - 10.1046/j.1442-2050.2003.00320.x IS - 2 M3 - Article N1 - Cited By :9 Export Date: 10 November 2020 PY - 2003 SP - 169-172 ST - Esophageal perforation caused by a press through pack T2 - Diseases of the Esophagus TI - Esophageal perforation caused by a press through pack UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0042063841&doi=10.1046%2fj.1442-2050.2003.00320.x&partnerID=40&md5=1a84c77b89d9edfc2bde6ffa3f0ac77a VL - 16 ID - 1652 ER - TY - JOUR AB - Foreign body ingestion is a commonly seen medical emergency in children. Retropharyngeal abscess and mediastinitis are well-documented complications from foreign body ingestion, which reflects the importance of early diagnosis. The neck radiograph is the most significant radiographic examination performed in a child with a suspected pharyngeal lesion. We report a case where the initial malpositioned lateral view neck radiograph failed to detect a potentially serious esophageal foreign body. A second lateral view neck radiograph discovered a mass of foreign body in the upper esophagus, which was found to be a chicken bone during surgery. The case suggests that a properly positioned neck radiograph is the most important examination in the initial evaluation of a child with suspected foreign body ingestion. © 2011. AD - Department of Pediatrics, Taipei Medical University Hospital, Taipei, Taiwan Department of Otolaryngology, Taipei Medical University Hospital, Taipei, Taiwan Department of Otolaryngology and School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan Department of Radiology, Taipei Medical University Hospital, Taipei, Taiwan Department of Radiology and School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan Department of Pediatrics and School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan AU - Chen, W. C. AU - Lee, F. P. AU - Lee, C. M. AU - Chen, C. M. DB - Scopus DO - 10.1016/j.jecm.2010.12.013 IS - 2 KW - Foreign body ingestion Neck radiograph Retropharyngeal abscess M3 - Article N1 - Export Date: 10 November 2020 PY - 2011 SP - 99-100 ST - Esophageal Foreign Body: A Case Report T2 - Journal of Experimental and Clinical Medicine TI - Esophageal Foreign Body: A Case Report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79954809837&doi=10.1016%2fj.jecm.2010.12.013&partnerID=40&md5=15d9a75ee80644e2e0ceb5edc1899084 VL - 3 ID - 1425 ER - TY - JOUR AD - Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, United States Division of Thoracic Surgery, Mayo Clinic, Rochester, MN, United States AU - Podgaetz, E. AU - Deschamps, C. DB - Scopus DO - 10.1016/j.jtcvs.2012.10.022 IS - 1 M3 - Article N1 - Cited By :8 Export Date: 10 November 2020 PY - 2013 SP - e9-e13 ST - Esophageal complications of catheter ablation for atrial fibrillation: A case report T2 - Journal of Thoracic and Cardiovascular Surgery TI - Esophageal complications of catheter ablation for atrial fibrillation: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84871188891&doi=10.1016%2fj.jtcvs.2012.10.022&partnerID=40&md5=e5b79aefabbdd749f0d773d0af76b0e3 VL - 145 ID - 1337 ER - TY - JOUR AN - 105009334. Language: English. Entry Date: 20101103. Revision Date: 20150818. Publication Type: Journal Article. Supplement Title: Nov2010 Supplement. Journal Subset: Biomedical DB - ccm DP - EBSCOhost KW - Treatment Errors -- Prevention and Control Operating Room Personnel Surgical Count Procedure Liability, Legal -- Prevention and Control Female Damages, Legal Retained Instruments -- Legislation and Jurisprudence N1 - Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2010 SN - 0190-5066 SP - 1-3 ST - Errors in surgery still are piling up, based on statistics from The Joint Commission T2 - Same-Day Surgery TI - Errors in surgery still are piling up, based on statistics from The Joint Commission UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105009334&site=ehost-live&scope=site ID - 877 ER - TY - JOUR AB - Most anterior epistaxis originates primarily from the Kiesselbach plexus, whereas posterior epistaxis is less common and originates from branches of the sphenopalatine artery. Risk factors include local trauma, foreign body insertion, substance abuse, neoplasms, inherited bleeding diatheses, or acquired coagulopathies. Assessment of airway, breathing, and circulation precedes identification of bleeding source, pain control, and achieving hemostasis. Management options include topical vasoconstrictors, direct pressure, cautery, tranexamic acid, nasal tampons, Foley catheters, or surgical intervention. Specialty consultation may be pursued if interventions fail. Disposition is typically to home unless posterior epistaxis or significant comorbidities exist that warrant admission. © 2018 Elsevier Inc. AD - Division of Emergency Medicine, University of Utah, 30 North 1900 East, Room 1C26, Salt Lake City, UT 84132, United States AU - Krulewitz, N. A. AU - Fix, M. L. DB - Scopus DO - 10.1016/j.emc.2018.09.005 IS - 1 KW - Anterior epistaxis ENT emergencies Epistaxis Posterior epistaxis TXA M3 - Review N1 - Cited By :5 Export Date: 10 November 2020 PY - 2019 SP - 29-39 ST - Epistaxis T2 - Emergency Medicine Clinics of North America TI - Epistaxis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85056710057&doi=10.1016%2fj.emc.2018.09.005&partnerID=40&md5=9625bd87af1fbca49006307672aaaa5a VL - 37 ID - 1024 ER - TY - JOUR AB - OBJECTIVES: The purpose of this study was to investigate the epidemiology of wire-bristle grill brush injury. STUDY DESIGN AND SETTING: Cross-sectional analysis of national databases; literature review. SUBJECTS AND METHODS: The Consumer Product Safety Commission's National Electronic Injury Surveillance System (NEISS) was used to derive a national weighted estimate of emergency department visits for wire bristle injury from 2002 to 2014. Date, location of injury, demographics, and outcomes were analyzed. A literature search and a consumer-reported injury database (SaferProducts.gov) were interrogated to provide ancillary sources of data. RESULTS: A total of 43 cases were found within the NEISS database, which extrapolated to an estimated 1698 (95% confidence interval, 1468-1927) emergency department visits nationwide. In the NEISS database, the mean age was 30 years, and the sex distribution of the patients was similar (21 males vs 22 females). The most common location of injury was the oropharynx in both the NEISS database (23 of 43, 53.4%) and the literature review (11 of 36, 30.5%). However, the oral cavity was the most frequent site in the consumer-reported SaferProducts.gov database (9 of 24, 37.5%). The majority of patients in the NEISS were treated in the emergency department (31 of 43, 69.7%). Raw case counts were highest in June, July, and August, with the highest number of events in the month of July. CONCLUSION: Injury from wire-bristle grill brush is uncommon but prevalent during certain seasons. Otolaryngologists play an important in the diagnosis and treatment of these injuries. Awareness among consumers and product manufacturers is necessary to promote safety. AD - University of Missouri School of Medicine, Department of Otolaryngology-Head and Neck Surgery, Columbia, Missouri, USA. University of Missouri School of Medicine, Columbia, Missouri, USA. University of Missouri School of Medicine, Department of Otolaryngology-Head and Neck Surgery, Columbia, Missouri, USA changda@health.missouri.edu. AN - 26932965 AU - Baugh, T. P. AU - Hadley, J. B. AU - Chang, C. W. DA - Apr DO - 10.1177/0194599815627794 DP - NLM ET - 2016/03/05 IS - 4 KW - Adult Consumer Product Safety Cross-Sectional Studies Emergency Service, Hospital/statistics & numerical data Female Foreign Bodies/*epidemiology/*surgery Household Products/*adverse effects Humans Male Mouth/*injuries Pharynx/*injuries Population Surveillance United States/epidemiology Neiss grill brush ingestion swallow wire bristle LA - eng N1 - 1097-6817 Baugh, Tiffany P Hadley, Jamie B Chang, C W David Journal Article England Otolaryngol Head Neck Surg. 2016 Apr;154(4):645-9. doi: 10.1177/0194599815627794. Epub 2016 Mar 1. PY - 2016 SN - 0194-5998 SP - 645-9 ST - Epidemiology of Wire-Bristle Grill Brush Injury in the United States, 2002-2014 T2 - Otolaryngol Head Neck Surg TI - Epidemiology of Wire-Bristle Grill Brush Injury in the United States, 2002-2014 VL - 154 ID - 173 ER - TY - JOUR AB - Purpose: To review the epidemiology of open globe injuries (OGI) presenting to a tertiary referral eye hospital in Sydney, Australia, over a 6-year period. Methods: Details of OGI presenting to the Sydney Eye Hospital over 6 years were reviewed. The Birmingham Eye Trauma Terminology system was used to classify injuries as globe ruptures, penetrating eye injuries (PEIs), intraocular foreign bodies (IOFBs) or perforating injuries. Demographic data, ocular history, mechanism of trauma, ocular injuries and bestcorrected visual acuity (BCVA) were recorded. The ocular trauma score (OTS) was calculated for each case and correlated with visual acuity following treatment. Results: There were 195 OGI: 78 globe ruptures, 65 PEIs, 46 IOFBs and six perforating injuries. Thirtytwo globe ruptures occurred due to a fall with 81.3% having previous intraocular surgery. Of 46 patients who sustained globe ruptures from causes other than a fall, 45.7% (21/46) had had intraocular surgery. Globe rupture patients had a lower OTS. Of 59 globe rupture patients who had their BCVA recorded following treatment, 88.1% had a BCVA of counting fingers or worse. Alcohol was implicated in 18 cases of OGI, with 10 due to assault. The OTS and initial BCVA correlated well with final BCVA. PEIs and IOFBs commonly occurred while working with metal. Conclusion: Intraocular surgery is associated with OGI, particularly globe rupture, with a poor visual outcome. Australia should consider a national registry for the collection of prospective data on severe ocular injuries. AD - N. Beshay, Save Sight Institute, University of Sydney, Sydney, NSW, Australia AU - Beshay, N. AU - Keay, L. AU - Watson, S. DB - Embase DO - 10.1111/ceo.12857 KW - alcohol assault Australia best corrected visual acuity demography eye injury eye surgery finger hospital human intraocular foreign body major clinical study nomenclature patient referral register rupture LA - English M3 - Conference Abstract N1 - L613435099 2016-12-01 PY - 2016 SN - 1442-9071 SP - 93 ST - The epidemiology of open globe injuries presenting to a tertiary referral eye hospital in Australia T2 - Clinical and Experimental Ophthalmology TI - The epidemiology of open globe injuries presenting to a tertiary referral eye hospital in Australia UR - https://www.embase.com/search/results?subaction=viewrecord&id=L613435099&from=export http://dx.doi.org/10.1111/ceo.12857 VL - 44 ID - 389 ER - TY - JOUR AB - A "fistula" is an abnormal connection between two epithelial surfaces. Fistulae are named based on the two surfaces or lumens they connect to. Fistulae form due to loss of wall integrity from an underlying insult, leading to the penetrance of an adjacent organ or epithelized surface. Common causes of small bowel fistulae include sequelae of surgical intervention, foreign body, bowel diverticula, Crohn's disease, malignancy, radiation, and infection. A histopathological analysis displays acute and/or chronic inflammation due to the underlying pathology. A thorough history and physical examination are important components of patient evaluation. Generally, patients will present with non-specific constitutional symptoms in addition to local symptoms attributed to the fistula. In rare instances, symptoms may be severe and life-threatening. Initial laboratory workup includes complete blood count, comprehensive metabolic panel, and lactate level. Radiologic imaging is useful for definitive diagnosis and helps delineate anatomy. In practice, computed tomography (CT) is the initial imaging modality. The addition of intravenous or enteric contrast may be helpful in certain situations. Magnetic resonance imaging (MRI) may also be used in special circumstances. Invasive procedures, such as endoscopy, can assist in the evaluation of mucosal surfaces to diagnose pathology such as inflammatory processes. Appropriate management should include optimizing nutritional status, delineating fistulous tract anatomy, skincare, and managing the underlying disease. A non-operative approach is generally accepted as the initial approach especially in the acute/subacute setting. However, operative intervention is indicated in the setting of failed non-operative management. Successful management of small bowel fistulae requires a multidisciplinary team approach. To conclude, a small bowel fistula is a complex clinical disease, with surgical intervention being the most common cause in developed countries. The non-operative approach should be trialed before an operative approach is considered. AD - General Surgery, Central Michigan University College of Medicine, Saginaw, USA. Surgery, Central Michigan University College of Medicine, Mount Pleasant, USA. Surgery, Stanford University, Palo Alto, USA. AN - 32461860 AU - Tuma, F. AU - Crespi, Z. AU - Wolff, C. J. AU - Daniel, D. T. AU - Nassar, A. K. C2 - PMC7243661 DA - Apr 22 DO - 10.7759/cureus.7789 DP - NLM ET - 2020/05/29 IS - 4 KW - crohn's disease fistula gastrointestinal malignancy malnutrition small bowel LA - eng N1 - 2168-8184 Tuma, Faiz Crespi, Zachary Wolff, Christopher J Daniel, Drew T Nassar, Aussama K Journal Article Review Cureus. 2020 Apr 22;12(4):e7789. doi: 10.7759/cureus.7789. PY - 2020 SN - 2168-8184 (Print) 2168-8184 SP - e7789 ST - Enterocutaneous Fistula: A Simplified Clinical Approach T2 - Cureus TI - Enterocutaneous Fistula: A Simplified Clinical Approach VL - 12 ID - 250 ER - TY - JOUR AB - Introduction: Enterocolic fistulas are usually caused by inflammatory conditions such as inflammatory bowel disease. The other causes are prior surgery, foreign bodies, pancreatitis, diverticulitis, intestinal tuberculosis and malignancies. Lymphoma accounts for up to 20% of all primary tumours of the small bowel, occurring most frequently in the terminal ileum and becoming progressively less frequent proximally. This study describes enterocolic fistula in a patient with jejunal lymphoma. Case report: An 56-year-old man presented with an acute diarrheal illness starting 14 days prior to hospital. He had daily fevers, chills, night sweat 1 month prior to hospital. His past medical history was significant for pulmonary tuberculosis in his 3rd decades, There was no prior history of abdominal surgery. The patient was ill looking, His laboratory tests showed hyponatremia, hypokalemia, hypoalbuminemia, the complete blood count revealed a normocytic normochromic anemia. The infectious diarrhea work-up was negative. A computed tomographic scan of the abdomen with intravenous contrast showed focal wall thickening in distal transverse colon with regional Lymph nodes During the colonoscopiy an fistula was identified at the distal-transverse colon with a communication to the small bowel. Colonoscope was not advanced through the fistula due to the risk of perforation. He was admitted to the hospital for operation and extended Rt. hemicolectomy and segmental jejunectomy was done. lymphoma was confirmed at surgical pathology. After surgery, the patient showed rapid recovery and the chemotherapy will be performed after full recovery from surgery. AD - H.B. Chun, Department of Internal Medicine AU - Chun, H. B. AU - Baek, I. H. AU - Lee, M. S. AU - Kim, H. J. AU - Kim, J. B. AU - Shin, S. R. AU - Kim, B. C. AU - Jung, S. Y. DB - Embase KW - colon fistula lymphoma small intestine Asia surgery hospital patient transverse colon fistula history of medicine lung tuberculosis abdominal surgery laboratory test hyponatremia hypokalemia hypoalbuminemia blood cell count normochromic normocytic anemia infectious diarrhea computer assisted tomography abdomen lymph node interpersonal communication colonoscope risk perforation hemicolectomy pathology chemotherapy inflammation enteritis pancreatitis intestinal tuberculosis primary tumor ileum case report diverticulitis human general aspects of disease fever night sweat foreign body LA - English M3 - Conference Abstract N1 - L70000938 2009-11-27 PY - 2009 SN - 0815-9319 SP - A65-A66 ST - Enterocolic fistula associated with small bowel lymphoma T2 - Journal of Gastroenterology and Hepatology TI - Enterocolic fistula associated with small bowel lymphoma UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70000938&from=export VL - 24 ID - 576 ER - TY - JOUR AB - Although well described in the colon, enteritis cystica profunda is an extremely rare lesion of the small intestine with only a few cases documented in English medical literature. It is a benign condition most often associated with Crohn's disease or Peutz-Jeghers syndrome in the adult. It has been described presenting as ileoileal intussusception in the pediatric population. We report a case of enteritis cystica profunda found incidentally on exploratory laparotomy with evidence of interval development over a 5-month period confirming trauma as the etiology. AD - Department of General Surgery, Naval Medical Center, 620 John Paul Jones Circle, Portsmouth, VA 23708-2197, United States Division of Colon and Rectal Surgery, Naval Medical Center, 620 John Paul Jones Circle, Portsmouth, VA 23708-2197, United States AU - Chao, J. C. AU - Lucha Jr, P. A. DB - Scopus DO - 10.7205/MILMED.173.5.513 IS - 5 M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2008 SP - 513-514 ST - Enteritis cystica profunda: Is trauma the etiology? Interval development in the previously normal ileum: A case report and literature review T2 - Military Medicine TI - Enteritis cystica profunda: Is trauma the etiology? Interval development in the previously normal ileum: A case report and literature review UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-43449124707&doi=10.7205%2fMILMED.173.5.513&partnerID=40&md5=aa634dcc1ecf766972c0c3e8ad7c5b62 VL - 173 ID - 1540 ER - TY - JOUR AN - 105425535. Language: English. Entry Date: 20091002. Revision Date: 20150818. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 9 KW - Negligence -- Legislation and Jurisprudence -- United States Retained Instruments Surgical Count Procedure Female Hysterectomy United States N1 - brief item; case study. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2009 SN - 0190-5066 SP - 90-91 ST - Ensuring no retained items is a shared responsibility T2 - Same-Day Surgery TI - Ensuring no retained items is a shared responsibility UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105425535&site=ehost-live&scope=site VL - 33 ID - 902 ER - TY - JOUR AN - 106874102. Language: English. Entry Date: 20031010. Revision Date: 20150818. Publication Type: Journal Article. Journal Subset: Biomedical DB - ccm DP - EBSCOhost IS - 7 KW - Foreign Bodies Liability, Legal Surgery, Operative -- Adverse Effects Surgical Instruments Female Surgical Count Procedure Treatment Errors United States N1 - Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2003 SN - 0190-5066 SP - 73-76 ST - Ensure equipment isn't left inside patient or face headlines, litigation: study estimates 1,500 pieces left inside patients annually T2 - Same-Day Surgery TI - Ensure equipment isn't left inside patient or face headlines, litigation: study estimates 1,500 pieces left inside patients annually UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106874102&site=ehost-live&scope=site VL - 27 ID - 867 ER - TY - JOUR AB - This study assesses the plasma-tissue exchange characteristics of the capsular tissue that forms around implants and how they are affected by implant porosity. The number of vessels and their permeability to rhodamine were measured by intravascular injection of the fluorophore tracer into Sprague-Dawley rats that hosted for 3-4 months polyvinyl alcohol (PVA) and polytetrafluoroethylene (PTFE) subcutaneous implants. Rats were implanted with four pore sizes of PVA - a nonporous PVA (PVA-skin), and 5, 60, and 700 micron mean pore sizes (PVA-5, PVA-60, and PVA-700, respectively) - and two pore sizes of PTFE: 0.50 (PTFE-0.5) and 5.0 (PTFE-5) mean micron pore sizes. Photodensitometric image analysis was used to quantify the local tracer extravasation and, hence the permeability coefficients of isolated vessels around the implants. The number of functional vessels within 100 μm of the implants highlighted by the lissamine-rhodamine tracer were counted with fluorescence microscopy and with H and E stained sections using brightfield microscopy. The permeability of vessels did not vary substantially with implant pore size but generally were lower than those measured for surrounding subcutis. Pore size, however, had a dramatic effect on the vascular density of tissue-encapsulating implants: the number of microvessels (under 10 μm in radius) within the tissue surrounding the porous implants was higher than the number around nonporous implants. Pore sizes on the order of cellular dimensions incited optimal neovascularization; the vascular density around PVA-60 implants was six times higher (p < .001) and three times higher (p < .001) than those around PVA-0 implants in the fluorescent images and in brightfield, respectively. Moreover, brightfield microscopy showed the number of vessels around PVA-60 implants was almost double those in normal subcutis. The results suggest that optimal vascular density around long-term implants, such as sensors, biofluid cell constructs, and immunoisolated cell systems, may be engineered with pore size. Plasma-tissue exchange properties of the capsular tissue were studied to determine the effects of implant porosity. The number of vessels and permeability to rhodamine were measured by intravascular injection of fluorophore tracer in to rats that hosted polyvinyl alcohol (PVA) and polytetrafluoroethylene (PTFE) implants. The permeability of the vessels did not vary with implant pore size, but pore size had an effect on the vascular density of tissue-encapsulating implants. Pore sized on the order of cellular dimensions incited neovascularizations. Brightfield microscopy showed the number of vessels around PVA-60 implants was almost double those in normal subcutis. AD - NSF Ctr. Emerging Cardiovasc. T., Department of Biomedical Engineering, Duke University, Durham, NC 27708-0295, United States AU - Sharkawy, A. A. AU - Klitzman, B. AU - Truskey, G. A. AU - Reichert, W. M. DB - Scopus DO - 10.1002/(SICI)1097-4636(19980615)40:4<586::AID-JBM10>3.0.CO;2-E IS - 4 KW - Encapsulation Foreign body response Permeability Porosity PTFE PVA Subcutaneous implants Vasculature M3 - Article N1 - Cited By :134 Export Date: 10 November 2020 PY - 1998 SP - 586-597 ST - Engineering the tissue which encapsulates subcutaneous implants. II. Plasma-tissue exchange properties T2 - Journal of Biomedical Materials Research TI - Engineering the tissue which encapsulates subcutaneous implants. II. Plasma-tissue exchange properties UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032527092&doi=10.1002%2f%28SICI%291097-4636%2819980615%2940%3a4%3c586%3a%3aAID-JBM10%3e3.0.CO%3b2-E&partnerID=40&md5=e1729f6743c3b84b5188a657c57e5351 VL - 40 ID - 1695 ER - TY - JOUR AB - Background: Aortoesophageal fistula (AEF) caused by the ingestion of foreignbodiesis rare and often life threatening. We aim to summarize effective measures to improve the curative effect and survival rate. Case Reports: Between January 2010 and September 2015, three patients with AEF received endovascular stent-graft treatment in our hospital. Through the effective prevention of hemorrhage by stent-grafting, surgical repair of the esophageal rupture was performed successfully. All three cases were treated successfully and survived up to the day that this article was written. Comments: It may be safer to first perform an endovascular stent-graft to prevent hemorrhage in AEF. © 2017, E-Century Publishing Corporation. All rights reserved. AD - Department of Gastroenterology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, China AU - Lu, C. AU - Gong, J. AU - Shen, Z. AU - Yu, C. AU - Li, Y. C7 - Ijcem0053198 DB - Scopus IS - 9 KW - Aortoesophageal fistula Foreign body Stent-graft M3 - Article N1 - Export Date: 10 November 2020 PY - 2017 SP - 13976-13981 ST - Endovascular stent-graft treatment in aortoesophageal fistula caused by foreign bodies T2 - International Journal of Clinical and Experimental Medicine TI - Endovascular stent-graft treatment in aortoesophageal fistula caused by foreign bodies UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030642098&partnerID=40&md5=4f76eeeb64ce9c21622c37625cf236b5 VL - 10 ID - 1121 ER - TY - JOUR AB - Background Anastomotic bleeding is an infrequent but life-threatening complication after stapled digestive tract anastomosis. Endovascular embolization is one of the available treatments, but precise clinical outcomes are yet to be evaluated. Purpose To evaluate the efficacy and safety of endovascular embolization for managing anastomotic bleeding after stapled digestive tract anastomosis. Material and Methods Twenty-eight patients were diagnosed with anastomotic bleeding after stapled digestive tract anastomosis by digital subtraction angiography (DSA). Curative effect was summed for analysis. Results All bleeding arteries were located in the stoma and were identified by contrast agent spillover by DSA. The offending arteries were superselectively catheterized and embolized with microcoils and/or gelatin sponge particles. Laboratory examinations showed normal hemoglobin and red blood cell counts when the patients' abdominal cavity drainage tubes stopped draining blood. The follow-up period was 3.2-84.7 months (median, 19.7 months). Four patients died during this time, of which two had cholangiocarcinoma, one had gastric cancer with tumor recurrence and multiple organ failure, and the final patient had a subarachnoid hemorrhage 4 months after embolization. In the surviving patients, no rebleeding occurred after embolization and no additional intervention or surgery was required. Conclusion Endovascular embolization is safe and effective for managing anastomotic bleeding after stapled digestive tract anastomosis. AD - X.-W. Han, Department of Interventional Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China AU - Li, T. F. AU - Duan, X. H. AU - Li, Z. H. E. N. AU - Ren, J. Z. AU - Zhang, K. A. I. AU - Huang, G. H. AU - Han, X. W. AU - Jiao, D. C. AU - Zhang, M. F. DB - Embase Medline DO - 10.1177/0284185114556492 IS - 11 KW - epinephrine adult aged anastomosis anastomosis bleeding arteriography artery catheterization article artificial embolization clinical article clinical effectiveness controlled study digital subtraction angiography embolization coil endovascular embolization feasibility study female gastric artery gastroduodenal artery gastroscopy human image analysis intestine endoscopy male microcoil patient safety postoperative complication priority journal stapled digestive tract anastomosis superior mesenteric artery surgical sponge LA - English M3 - Article N1 - L607901196 2016-01-29 2016-02-04 PY - 2015 SN - 1600-0455 0284-1851 SP - 1368-1372 ST - Endovascular embolization for managing anastomotic bleeding after stapled digestive tract anastomosis T2 - Acta Radiologica TI - Endovascular embolization for managing anastomotic bleeding after stapled digestive tract anastomosis UR - https://www.embase.com/search/results?subaction=viewrecord&id=L607901196&from=export http://dx.doi.org/10.1177/0284185114556492 VL - 56 ID - 423 ER - TY - JOUR AD - Current affiliations: Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States AU - Obstein, K. L. AU - Thompson, C. C. DB - Scopus DO - 10.1016/j.gie.2009.03.1168 IS - 6 M3 - Review N1 - Cited By :19 Export Date: 10 November 2020 PY - 2009 SP - 1161-1166 ST - Endoscopy after bariatric surgery (with videos) T2 - Gastrointestinal Endoscopy TI - Endoscopy after bariatric surgery (with videos) UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-70849105033&doi=10.1016%2fj.gie.2009.03.1168&partnerID=40&md5=ac794aeb9108c21debcd280c6c29e157 VL - 70 ID - 1480 ER - TY - JOUR AB - Cases of foreign body ingestion are encountered relatively often in clinical settings; however, serious complications are rare. In such cases, mediastinal abscess due to esophageal perforation can become a life-threatening complication. Although highly invasive, surgery is often used as the first-line treatment. We herein report the case of a 65-year-old woman who presented with complaints of progressive odynophagia and dysphagia for 2 weeks following a fish meal. Enhanced cervicothoracic computed tomography demonstrated an enhanced round mass with peripheral contrasted margins. The mass was diagnosed as a mediastinal abscess resulting from esophageal perforation caused by a fish bone. Endoscopic ultrasound-guided abscess drainage (EUS-AD) was performed using a nasobiliary drainage tube (NDT). Two weeks later, the abscess had completely disappeared. EUS-AD was safe and effective in this case; furthermore, external drainage using NDT was suitable for this abscess located very close to the upper esophageal sphincter. © 2019 The Japanese Society of Internal Medicine. AD - Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, Japan Department of Gastroenterology, Yurikumiai General Hospital, Japan Department of Gastroenterology, Narita Memorial Hospital, Japan AU - Shibuya, H. AU - Ikehara, H. AU - Andoh, K. AU - Horii, T. AU - Moriyama, M. AU - Yamao, K. AU - Gotoda, T. DB - Scopus DO - 10.2169/internalmedicine.1992-18 IS - 15 KW - Endoscopic ultrasound-guided abscess drainage Fish bone Mediastinal abscess M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 2173-2177 ST - Endoscopic ultrasound-guided drainage of a mediastinal abscess caused by an ingested fish bone T2 - Internal Medicine TI - Endoscopic ultrasound-guided drainage of a mediastinal abscess caused by an ingested fish bone UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85070498250&doi=10.2169%2finternalmedicine.1992-18&partnerID=40&md5=12b30ff87518f73ce13b135adf7d39c0 VL - 58 ID - 1036 ER - TY - JOUR AB - Purpose: Gastric outlet obstruction often presents with nausea and vomiting and usually develops over weeks to months. The most common causes of gastric outlet obstruction are peptic ulcers, malignancy, bezoars, foreign bodies, and pyloric stenosis. Methods: We report a case of intermittent gastric obstruction caused by a prolapsing hyperplastic gastric antral polyp. Results: A healthy 44-year-old female presented with 3 months of intermittent dull mid abdominal pain, nausea and intermittent non-bloody, non-bilious vomiting. She also described early satiety and a weight loss of 8 pounds over the 3 months. She was otherwise healthy and took no medications. On physical exam she had normal bowel sounds, and mild tenderness over the epigastric region. She had a negative Murphy's sign, and the spleen and liver were normal. Her complete blood count was normal, with no anemia. Upper endoscopy was recommended to further investigate the patient's pain, nausea, vomiting and weight loss. On upper endoscopy, a 3 cm pedunculated, prolapsing, polyp was found arising in the gastric antrum and causing ball-valve effect within the pylorus and near complete obstruction of the pyloric channel. The polyp was observed to cause intermittent gastric outlet obstruction. The polyp was completely resected by a monopolar polypectomy using a large snare and sent for pathology. Pathology showed a hyperplastic polyp without evidence of metaplasia, dysplasia or malignancy. Random gastric biopsies showed chronic inactive gastritis and no evidence of Helicobacter pylori. At the follow-up 12 months after the polypectomy, the patient remained symptom free. Conclusion: We report the case of a patient with intermittent symptomatic gastric outlet obstruction caused by a benign prolapsing gastric polyp treated by endoscopic snare resection. There are 39 previously reported cases of gastric polyps leading to gastric outlet obstruction. Gastric polyps causing gastric outlet obstruction are more common in females (23 cases) with median age of onset of 72 years in females. Previously reported polyps arise from the antrum and have a median size of 5 cm (1.5-8 cm). They can be managed surgically with excision, or endoscopically with snare polypectomy or endoscopic mucosal resection (EMR) of sessile polyps. The median size of endoscopically removed polyps is 3 cm, with largest reported in the literature being 8 cm. Complications of endoscopic management include bleeding and perforation. Gastric polyps should be considered in the differential diagnosis of a patient who present with intermittent gastric outlet obstruction. Endoscopic management with snare resection is a good option if technically feasible and can result in a long term response. AD - S. Brozovic, Brigham and Women's Hospital, Boston, MA, United States AU - Brozovic, S. AU - Saltzman, J. DB - Embase DO - 10.1038/ajg.2012.273 KW - stomach obstruction polyp college gastroenterology human stomach polyp patient polypectomy female endoscopy vomiting pathology nausea body weight loss surgery pylorus stenosis intestine sound follow up drug therapy spleen Helicobacter pylori gastritis foreign body stomach biopsy satiety bezoar nausea and vomiting metaplasia obstruction pylorus stomach antrum pain dysplasia peptic ulcer anemia blood cell count endoscopic mucosal resection liver onset age abdominal pain excision bleeding perforation differential diagnosis LA - English M3 - Conference Abstract N1 - L70894346 2012-10-18 PY - 2012 SN - 0002-9270 SP - S299 ST - Endoscopic treatment of intermittent gastric outlet obstruction caused by a prolapsing gastric antral polyp T2 - American Journal of Gastroenterology TI - Endoscopic treatment of intermittent gastric outlet obstruction caused by a prolapsing gastric antral polyp UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70894346&from=export http://dx.doi.org/10.1038/ajg.2012.273 VL - 107 ID - 504 ER - TY - JOUR AB - Flanged ventricular catheters are now used infrequently. Many patients with longstanding hydrocephalus still harbor these catheters, either as their current ventricular catheter, or as a retained catheter from a prior implant. The removal of flanged ventricular catheters is sometimes necessary, and may be challenging due to intraventricular adhesions. We describe the use of an endoscopic technique for the successful retrieval of flanged ventricular catheters in two patients. The technique described in this report may be helpful for patients that have flanged ventricular catheters that must be removed. © Copyright 2018 The Canadian Journal of Neurological Sciences Inc. AD - Faculty of Medicine, Dalhousie University, Halifax, NS, Canada Division of Neurosurgery, Kingston Public Hospital, Kingston, Jamaica Division of Neurosurgery, Department of Surgery, IWK Health Centre, Dalhousie University, 5850 University Avenue, Halifax, NS B3K 6R8, Canada AU - Babadagli, M. E. AU - Cooke, D. AU - Walling, S. A. AU - McNeely, P. D. DB - Scopus DO - 10.1017/cjn.2018.336 IS - 6 KW - Cerebrospinal Fluid Shunts Hydrocephalus Neuroendoscopy M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 SP - 692-695 ST - Endoscopic Retrieval of Flanged Ventricular Catheters T2 - Canadian Journal of Neurological Sciences TI - Endoscopic Retrieval of Flanged Ventricular Catheters UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85056623794&doi=10.1017%2fcjn.2018.336&partnerID=40&md5=1e479ab1c8aed60399071da58fa8942e VL - 45 ID - 1058 ER - TY - JOUR AB - Case: A 35- year old patient was referred to us after a 30 mm gastric subepithelial mass was noted on upper endoscopy. Technique: Endoscopic ultrasound showed a 30 mm mass arising from the muscularis propria on the lesser curvature. The margins were well defined and no cystic spaces within the mass were noted. Patient was offered the options of laparoscopic or endoscopic removal, and she chose the latter. Patient was brought to the operating room and general anesthesia was administered. A detatchable, plastic ligature was carefully placed around the base on the lesion to decrease the risk of bleeding and also in an attempt to separate the tumor capsule from the outer muscle fibers. A 30-mm oval snare was then used to resect the base of the subepithelial tumor. Using a foreign body retrieval net the resected tumor was brought in to the esophagus but we were unable to retrieve it beyond the upper esophageal sphincter. An esophageal overtube was then advanced into the distal esophagus and the tumor was pulled into the overtube and the overtube was withdrawn. Two over the scope closure devices were used to close the resection defect. Pathology revealed a 30 mm tumor with an intact capsule and bland spindle cells. The mitotic count was 4 per 50 high power fields. Immunohistochemistry for CD117 was strongly positive. Discussion: The National Comprehensive Cancer Network guidelines recommend that while gastrointestinal stromal tumors smaller than 2 cm can be managed conservatively with surveillance, lesions larger than 2 cm should be surgically. There are no recommendations for the role of endoscopic resection of these tumors. A recent study comparing surgical with endoscopic resection for GISTs, showed that endosopic resection had shorter procedure time and length of stay but also had lower R0 resection rates. Still there was no significant difference in the recurrence rates. The challenges to endoscopic resection include achieving a tumor free margin, closure of the full thickness defect and en-bloc tissue extraction. Technical considerations for endoscopic resection of GISTs include the use of EUS to define the anatomy and the use of endoscopic ligature to separate the tumor from outer muscle fibers. Meticulous attention to closure of the defect is imperative and overtube can be used to facilitate tumor extraction. Conclusion: Loop and snare resection of gastric stromal tumors can be considered prior to laparoscopic resection in selected cases where the tumor resection defect can be successfully closed with endoscopic techniques. AD - A. Singh, Gastroenterology and Hepatology, Case Western Reserve University, Chicago, IL, United States AU - Singh, A. AU - Ali, M. A. AU - Bagby, C. AU - Marks, J. M. AU - Chak, A. DB - Embase IS - 5 KW - plastic neoplasm endoscopic surgery surgery human patient muscle cell esophagus extraction bleeding risk gastrointestinal stromal tumor procedures pathology endoscopic ultrasonography upper esophagus sphincter devices general anesthesia cancer surgery spindle cell immunohistochemistry thickness length of stay recurrence risk foreign body tissues operating room endoscopy LA - English M3 - Conference Abstract N1 - L72293865 2016-05-31 PY - 2016 SN - 1097-6779 SP - AB645 ST - Endoscopic resection of a 30mm gastric stromal tumor T2 - Gastrointestinal Endoscopy TI - Endoscopic resection of a 30mm gastric stromal tumor UR - https://www.embase.com/search/results?subaction=viewrecord&id=L72293865&from=export VL - 83 ID - 405 ER - TY - JOUR AB - Background: Dogs and cats with acute signs of choking, retching, cough, vomiting, regurgitation, hypersalivation, dysphagia and odynophagia should have the presence of a gastrointestinal foreign body (FB) as part of their differential diagnosis, where it is a frequent condition in the care of small animals. Most objects lodged in the esophagus, stomach, and proximal duodenum can be removed by upper digestive endoscopy, a curative, little invasive procedure. The objective of our study was to evaluate the physical aspects and location of esophageal and gastric FBs observed in 88 dogs and the age and breed of the affected animals, and to determine the success rate and eventual complications associated with the procedure as well. Materials, Methods & Results: Eighty-eight cases of dogs, males and females of varying ages and breeds, submitted to upper digestive endoscopy were selected because of suspicion of esophageal or gastric FBs. The endoscopic procedure aimed at confirming the diagnosis, whether or not followed by endoscopic removal of these objects. Prior to endoscopy, the animals had laboratory tests (blood count and serum biochemistry) and subsequently to the anesthetic protocols of choice for each case. Data including breed, age, type of constituent material and anatomical location of the FB, endoscopic procedure success rate and complications were recorded and descriptively evaluated. Of the 88 dogs evaluated, 60% (n = 53) were male and 40% (n = 35) female. According to the breed of the animals, 55% (n = 49) were small-breed dogs, 29% (n = 25) large-breed dogs, and 8% (n = 7) medium-breed dogs, and 8% were of mixed breed dogs, which could assume various sizes. Shih tzus accounted for 18% (n = 16) of the animals, Lhasa apso 8% (n = 7) and mixed breed 8% (n = 7), where these were the most frequently affected breeds. Regarding age, animals 1 to 5 years old represented 66% (n = 58) of the patients, and those 6 to 10 years old accounted for 20% (n = 18), while 11% of the dogs were over 10 years old (n = 10). Two animals (3%) had no information about their ages. Pieces of cloth were the most frequently found FBs, representing 20% (n = 20), followed by animal bones (19%) and fruit pits (10%). As for location, 78% (n = 69) of the FBs were located in the stomach and 22% (n = 19) in the esophagus. The success rate of endoscopic FB removal in this study was 83% (n = 73). In 76% (n = 67) of the animals, there were no complications due to the presence of FB in the upper gastrointestinal tract. The most frequent complications were esophageal ulcerations (n = 7) and inability to move the FB (n = 5) and adherences (n = 4). Discussion: The results showed that small-breed dogs, especially Shih tzus and Yorkshires, represented a larger number of cases, probably due to their popularity in Brazil, where the study was conducted. Males were more prevalent than females, and the most affected age was between 1 and 5 years, with emphasis on younger animals. There were more gastric FB cases compared to esophageal FB cases, which was related to the interval between ingestion of the object and veterinary care. Although not the most prevalent FB, the high rate of mango pits can be explained by the vast number of mango trees in the Federal District. There were few complications compared to the success of cases, indicating that endoscopy is the procedure of choice for the diagnosis and removal of FBs from the gastrointestinal tract. AD - P.D. Galera, Faculdade de Agronomia e Medicina Veterinária - UnB, Campus Darcy Ribeiro - ICC Sul, Brasília, DF, Brazil AU - Poggiani, F. M. AU - Da Costa Duarte, R. P. AU - Santana, M. I. S. AU - Galera, P. D. DB - Embase DO - 10.22456/1679-9216.100574 KW - animal experiment animal model animal tissue article biochemistry blood cell count bone Brazil complication controlled study endoscopy esophagus foreign body esophagus ulcer female human ingestion laboratory test male mango mongrel dog nonhuman Shih Tzu stomach surgery upper gastrointestinal tract veterinary medicine LA - English M3 - Article N1 - L632997396 2020-10-19 PY - 2020 SN - 1679-9216 1678-0345 ST - Endoscopic removal of foreign body in upper gastrointestinal tract in dogs: Success rate and complications T2 - Acta Scientiae Veterinariae TI - Endoscopic removal of foreign body in upper gastrointestinal tract in dogs: Success rate and complications UR - https://www.embase.com/search/results?subaction=viewrecord&id=L632997396&from=export http://dx.doi.org/10.22456/1679-9216.100574 VL - 48 ID - 301 ER - TY - JOUR AB - Ingestion of foreign bodies is common in clinical practice. Most ingested foreign bodies will pass through the gastrointestinal (GI) tract without any problems. While GI tract injury due to the ingested foreign body such as a toothpick, a fishbone, a date pit, or a chicken bone, is common, duodenal perforation is rare. In this report, our experience with this rare entity is shared. We present a 38-year-old male patient with GI tract perforation in the bulbus of the duodenum due to a leg of glasses. The patient was admitted to our hospital with severe abdominal pain. Right upper quadrant tenderness was detected at physical examination, and leukocytosis on the laboratory test results. Plain X-ray and computerized tomography showed an ingested foreign body in the bulbus of the duodenum. A leg of glasses perforating the duodenum was removed with endoscopy. The patient was managed nonoperatively, and discharged without any complications on the eighth day after endoscopy. Endoscopic removal and nonoperative management may be feasible in carefully selected patients with duodenal-perforating foreign bodies. © 2016 The Author(s) Published by S. Karger AG, Basel. AD - Department of Gastroenterology, Affiliated 81st Hospital of Nanjing University of Chinese Medicine, Jiangsu Province, Nanjing, China Department of Anesthesiology, Affiliated 81st Hospital of Nanjing University of Chinese Medicine, Nanjing, China AU - Wang, L. AU - Wen, W. AU - Huang, J. AU - Hu, W. AU - Zhou, R. AU - Li, X. AU - Wang, X. DB - Scopus DO - 10.1159/000452205 IS - 3 KW - Duodenal perforation Endoscopic removal Foreign body M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2016 SP - 679-684 ST - Endoscopic removal of a duodenal-perforating leg of glasses with dormia basket T2 - Case Reports in Gastroenterology TI - Endoscopic removal of a duodenal-perforating leg of glasses with dormia basket UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84995738082&doi=10.1159%2f000452205&partnerID=40&md5=a2014ea9cc29e2a4c063ec6d621c15b2 VL - 10 ID - 1168 ER - TY - JOUR AB - Introduction: Ingested foreign bodies (IFB) can uncommonly cause perforation of the gastrointestinal tract. The traditional management is surgical exploration via laparotomy or laparoscopy, although endoscopic options are now gaining prominence. Presentation of case: We present two patients with almost identical clinical presentations of post-prandial abdominal pain and anorexia. On examination they were haemodynamically stable with localised epigastric tenderness. Both patients underwent CT scan of the abdomen, with one scan revealing a foreign body in the stomach penetrating the full thickness of the gastric wall with the tip lying extraluminally. They subsequently underwent endoscopy where a chicken bone was found perforating the wall of the stomach. This was removed via snare and endoscopic clips were used to close the site of perforation. Discussion: The majority of ingested foreign bodies pass through the gastrointestinal tract harmlessly. However some IFBs can cause significant complications like bowel obstruction, bleeding, abscess formation, migration to other organs, and in our case perforation. The diagnosis may be delayed due to an insidious clinical presentation especially if the patient does not recall ingesting anything untoward. Our patients managed to avoid surgery by undergoing successful endoscopic therapy. Conclusion: In selected cases, endoscopic management is more cost-effective, minimally invasive, has less post-operative complications, and leads to a more expeditious recovery. Therefore, the role of therapeutic endoscopy for gastric perforations secondary to foreign bodies should always be considered. © 2019 The Author(s) AD - General Surgery, Bunbury Regional HospitalWestern Australia, Australia AU - Sidiqi, M. M. AU - Sharma, S. AU - Muhammed, A. H. DB - Scopus DO - 10.1016/j.ijscr.2019.11.010 KW - Complication Endoscopy Foreign-body Gastric Perforation M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 305-308 ST - Endoscopic management of gastric perforation secondary to chicken bone: A report of 2 cases T2 - International Journal of Surgery Case Reports TI - Endoscopic management of gastric perforation secondary to chicken bone: A report of 2 cases UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85075197246&doi=10.1016%2fj.ijscr.2019.11.010&partnerID=40&md5=ede967a6eca51ffda091c4474b694c17 VL - 65 ID - 1033 ER - TY - JOUR AB - Background: Endoscopic therapy for GERD is an appealing, minimally invasive alternative to medical treatment and surgery. Various materials have been tested to augment the lower esophageal sphincter (LES), with limited success. To our knowledge, safety and migration of polymethylmethacrylate (PMMA) microspheres has never been evaluated. Objective: To assess the safety, migration, inflammatory reaction, and durability of PMMA injected into the LES of miniature swine to create a reflux barrier. Design: Animal study. Setting: Approved animal research facilities. Intervention: Injection of the LES of miniature swine with PMMA. Histopathology of the injected site at certain intervals and postnecropsy microsphere counts of various organs. Main Outcome Measurements: Minimal inflammatory reaction at the injection site, persistent bulking effect of the material, and no migration of microspheres. Results: Injection of LES with PMMA caused a mild inflammatory reaction. The bulking effect of the injected material was persistent. Migration of microspheres was eliminated with the use of larger-sized microspheres. Limitations: Animal model. Conclusion: Our phase I study documented that 40-μm polymethylmethacrylate microspheres are biocompatible and that PMMA microspheres are resistant to degradation when injected submucosally into the wall of the esophagus. The detection of 40-μm PMMA microspheres in local lymph nodes, liver, and lungs of some animals in the phase I study clearly documented transport of PMMA away from the injection site. This finding was eliminated by increasing the size of microspheres to 125 μm. The potential therapeutic effects of these larger microspheres for humans with GERD remains to be evaluated. Copyright © 2010 by the American Society for Gastrointestinal Endoscopy. AD - Division of Gastroenterology, Department of Medicine, University of California, San Diego, CA, United States Division of Gastroenterology/Hepatology, Indiana University Medical Center, Indianapolis, IN, United States AU - Kamler, J. P. AU - Lemperle, G. AU - Lemperle, S. AU - Lehman, G. A. DB - Scopus DO - 10.1016/j.gie.2010.02.035 IS - 2 M3 - Article N1 - Cited By :12 Export Date: 10 November 2020 PY - 2010 SP - 337-342 ST - Endoscopic lower esophageal sphincter bulking for the treatment of GERD: Safety evaluation of injectable polymethylmethacrylate microspheres in miniature swine T2 - Gastrointestinal Endoscopy TI - Endoscopic lower esophageal sphincter bulking for the treatment of GERD: Safety evaluation of injectable polymethylmethacrylate microspheres in miniature swine UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77955710699&doi=10.1016%2fj.gie.2010.02.035&partnerID=40&md5=3174f5a768db634d7358c0c4312b814a VL - 72 ID - 1454 ER - TY - JOUR AB - Background: The most serious complication of ureter stent is long-term retention of ureteral stent and stone formation around the stent. Case presentation: A 51-year old female patient with left ureteral stent placed 2 years before developed both pyelic and vesical stones on the two ends of the double J was admitted to our hospital. Intravesical lithotripsy, retrograde ureteroscopy, and percutaneous nephrolithotripsy were performed with the patient in the prone split-leg position. All the stones and the ureteral stent were successfully removed in a single session. Conclusions: Combined endoscopic techniques in the prone split-leg position can effectively and safely manage severely encrusted stents. © 2020 The Author(s). AD - Department of Urology, Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China AU - Wang, D. AU - Sun, H. AU - Chen, L. AU - Liu, Z. AU - Zhang, D. AU - Yu, D. AU - Ding, D. C7 - 37 DB - Scopus DO - 10.1186/s12894-020-00606-5 IS - 1 KW - Encrusted ureteral stent Endoscopic combined intrarenal surgery Prone-split leg position M3 - Article N1 - Export Date: 10 November 2020 PY - 2020 ST - Endoscopic combined intrarenal surgery in the prone-split leg position for successful single session removal of an encrusted ureteral stent: A case report T2 - BMC Urology TI - Endoscopic combined intrarenal surgery in the prone-split leg position for successful single session removal of an encrusted ureteral stent: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85083071413&doi=10.1186%2fs12894-020-00606-5&partnerID=40&md5=82f74e5b708a87f79a1951cbae661825 VL - 20 ID - 969 ER - TY - JOUR AB - Background: Many cases of post-operative and posttraumatic endophthalmitis are being managed at the Khyber Institute of Ophthalmic Medical Sciences, Peshawar in Pakistan but no study has been done to ascertain the magnitude of the disease and to also evaluate the visual outcome after management. Methods: The case notes of 39 patients diagnosed with posttraumatic and postoperative endophthalmitis between May 2006 and April 2007 were analyzed and clinical characteristics obtained were documented and tabulated. Results: During the study period, 2474 patients were admitted in both the male and female wards. Of these, 39 (1.6%) had endophthalmitis due to surgical and traumatic complications. In all, 6 (12.4%) patients had evisceration, while 21 (53.8%) patients who had topical antibiotics consisting of ofloxacin, 0.1% corticosteroids, fortified cetazoline and 1% atropine along with intravitreal antibiotics, a combination of 0.1mg vancomycin and 0.4mg amikacin, were discharged home with a visual acuity of counting fingers to light perception. Conclusion: Endophthalmitis is a serious ocular complication of open globe injury and intraocular surgery. The frequency in this center has been noted to be very high as compared to other places. Its management is very challenging and often leads to devastating structural and functional damage to the eye; causing severe frustration to both the patient and the attending physician. Efforts must be made to prevent the condition. AD - Department of Ophthalmology, Jos University Teaching Hospital, Jos, Nigeria Khyber Institute of Ophthalmic Medical Science, Hayatabad Medical Complex, Peshawar, Pakistan AU - Wade, P. D. AU - Khan, S. S. AU - Khan, M. D. DB - Scopus DO - 10.4103/1596-3519.55759 IS - 1 KW - Endophthalmitis Magnitude Visual outcome M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2009 SP - 19-24 ST - Endophthalmitis: Magnitude, treatment and visual outcome in Northwest frontier province of Pakistan T2 - Annals of African Medicine TI - Endophthalmitis: Magnitude, treatment and visual outcome in Northwest frontier province of Pakistan UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-70349158106&doi=10.4103%2f1596-3519.55759&partnerID=40&md5=be5e97af86b1e85eb191d4dcebd33593 VL - 8 ID - 1488 ER - TY - JOUR AB - Objective: To report a case of endophthalmitis following ocular penetrating injury with intraocular foreign body, its management and outcome. Method: Case Report. Results: A 34 years old Indonesian male was admitted for sudden painful reduced vision in right eye. He had a history of foreign body hitting his right eye while wielding a hammer two days prior to presentation. Visual acuity was counting finger OD, 6/12 OS and RAPD negative. Examination showed full thickness sclera laceration wound at 9 o'clock with hypopyon and fibrin in anterior chamber. There was severe vitritis. CT scan revealed presence of intraocular foreign body in the right eye. Patient was started on systemic ciprofloxacin and given intravitreal fortum and ceftazidime during right eye sclera laceration wound toilet and suturing with vitreous tapping on the same day. Following primary suturing, patient underwent pars plana vitrectomy, removal of intraocular foreign body and silicone oil insertion. Culture and sensitivity test from vitreous showed Flavobacterium spp and clinically patient responded to topical antibiotics. Postoperatively patient's vision improved to 2/60. Conclusion: Post-traumatic endophthalmitis is an uncommon but severe complication of ocular trauma with its incidence rate of 2.1% of all open globe injury. The incidence increases up to 5% when associated with IOFB. IOFB is most commonly caused by metal hammering metal. The decision whether to remove as a primary procedure or subsequent surgery depends on the IOFB size and material, visual potential, surgeon, and patient preference. Discussion with a vitreoretinal surgeon is crucial in the early management. AD - M.B.T.H. Basri, Pusat Perubatan Universiti Kebangsaan Malaysia, Universiti Kebangsaan, Malaysia AU - Basri, M. B. T. H. AU - Zahidin, A. Z. B. T. M. AU - Mustapha, M. B. T. DB - Embase KW - ceftazidime ciprofloxacin fibrin silicone oil adult anterior eye chamber body size case report clinical article complication conference abstract drug combination drug therapy endophthalmitis eye injury finger Flavobacterium human hypopyon incidence Indonesian intraocular foreign body laceration low vision male nonhuman pars plana vitrectomy patient preference sclera surgeon surgery topical drug administration visual acuity vitreous body vitritis wound care x-ray computed tomography LA - English M3 - Conference Abstract N1 - L625431766 2018-12-18 PY - 2018 SN - 0300-5283 SP - 29 ST - Endophthalmitis as the first presentation following ocular penetrating injury with intraocular foreign body (IOFB) T2 - Medical Journal of Malaysia TI - Endophthalmitis as the first presentation following ocular penetrating injury with intraocular foreign body (IOFB) UR - https://www.embase.com/search/results?subaction=viewrecord&id=L625431766&from=export VL - 73 ID - 339 ER - TY - JOUR AB - We have never experienced encapsulation or massive thrombosis of a Björk-Shiley aortic valve prosthesis in a patient receiving an adequate anticoagulation treatment. An encapsulation has, however, been described after many different types of heart valve replacements. Early diagnosis and emergency operation are mandatory. We have only encountered two cases of massive thrombosis in Björk-Shiley tilting disc valve prostheses in the aortic position out of 300 implants. Anticoagulant treatment was not given in either case. One patient died before final diagnosis was made and the other underwent an emergency operation. It was possible to clean out all thrombus material on both sides of the valve after temporary removal of ths disc and rotation of the valve. This method cannot, however, be recommended for general use. If the surgeons are not experienced in the proper removal of the disc, they will bend the struts so that the disc will not function properly after re-insertion. The insertion of a new prosthesis is a safer procedure. As we have never found encapsulation of an aortic prosthesis after adequate anticoagulation, this treatment is, therefore, recommended. © 1973 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. AD - Thoracic Surgical Clinic, Karolinska Sjukhuset, Stockholm, Sweden AU - Björk, V. O. AU - Henze, A. DB - Scopus DO - 10.3109/14017437309139160 IS - 1 M3 - Article N1 - Cited By :28 Export Date: 10 November 2020 PY - 1973 SP - 17-20 ST - Encapsulation of the björk-shiley aortic disc valve prosthesis caused by the lack of anticoagulation treatment T2 - Scandinavian Cardiovascular Journal TI - Encapsulation of the björk-shiley aortic disc valve prosthesis caused by the lack of anticoagulation treatment UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015536796&doi=10.3109%2f14017437309139160&partnerID=40&md5=1ad0d1f6b1526b222d48359c31de0d7c VL - 7 ID - 1784 ER - TY - JOUR AB - AIM: To investigate the relationship between encapsulating peritonitis and familial Mediterranean fever (FMF). METHODS: The patient had a history of type 2 diabetes and laparoscopic cholecystectomy was performed one year ago for cholelithiasis. Eleven months after the operation she developed massive ascites. Biochemical evaluation revealed hyperglycemia, mild Fe deficiency anemia, hypoalbuminemia and a CA-125 level of 2 700 IU. Ascitic evaluation showed characteristics of exudation with a cell count of 580/mm(3). Abdominal CT showed omental thickening and massive ascites. At exploratory laparotomy there was generalized thickening of the peritoneum and a laparoscopic clip encapsulated by fibrous tissue was found adherent to the uterus. Biopsies were negative for malignancy and a prophylactic total abdominal hysterectomy and bilateral salpingooophorectomy were performed. RESULTS: The histopathological evaluation was compatible with chronic nonspecific findings and mild mesothelial proliferation and chronic inflammation at the uterine serosa and liver biopsy showed inactive cirrhosis. CONCLUSION: The patient was evaluated as sclerosing encapsulating peritonitis induced by the laparoscopic clip acting as a foreign body. Due to the fact that the patient had FMF the immune response was probably exaggerated. AD - Department of Family Medicine, Kartal State Hospital, 36660 Istanbul, Turkey. AN - 15884137 AU - Dabak, R. AU - Uygur-Bayramiçli, O. AU - Aydin, D. K. AU - Dolapçioglu, C. AU - Gemici, C. AU - Erginel, T. AU - Turan, C. AU - Karadayi, N. C2 - PMC4305931 DA - May 14 DO - 10.3748/wjg.v11.i18.2844 DP - NLM ET - 2005/05/11 IS - 18 KW - Aged Cholelithiasis/surgery Familial Mediterranean Fever/*complications Female Foreign Bodies/*complications Humans Laparoscopy/*adverse effects Peritonitis/*etiology Surgical Instruments/*adverse effects LA - eng N1 - 2219-2840 Dabak, Resat Uygur-Bayramiçli, Oya Aydin, Didem-Kiliç Dolapçioglu, Can Gemici, Cengiz Erginel, Turgay Turan, Cem Karadayi, Nimet Case Reports Journal Article Review World J Gastroenterol. 2005 May 14;11(18):2844-6. doi: 10.3748/wjg.v11.i18.2844. PY - 2005 SN - 1007-9327 (Print) 1007-9327 SP - 2844-6 ST - Encapsulating peritonitis and familial Mediterranean fever T2 - World J Gastroenterol TI - Encapsulating peritonitis and familial Mediterranean fever VL - 11 ID - 53 ER - TY - JOUR AB - Aims: A case report with video of young patient admitted as emergency with peritonitis, there was history of insertion of foreign body (toilet Brush) in his rectum. Methods: 32 years old male was admitted in accident and emergency with abdominal pain. Pain started 6 h ago after he inserted the toilet brush in his back passage. He was septic with four quadrant peritonitis. His white cell count and C-reactive proteins were elevated. Plain X-ray abdomen showed free gas under the diaphragm. No further images were done. Patient was prepared for theatre and laparoscopy was carried out by general surgeon, three 5 mm and two 10 mm ports were used. Found to have faecal peritonitis due to iatrogenic perforation just above the recto-sigmoid junction. The perforation was closed with Ethibond stitches. All quadrant under vision peritoneal wash was done with 8 litres of saline. The bowel clamp was applied to the sigmoid colon and flexible sigmidoscopy carried out and pelvis was flooded with saline, there was no air leak from the repaired perforation. The sigmoid colon was mobilized and loop colostomy was performed in left iliac fossa at the 10 mm port site. Results: The post operative period was uneventful the patient was referred to psychiatrist. And had now loop colostomy revered with no long term follow-up. Conclusion: Laparoscopic emergency colonic surgery is safe with good results by a laparoscopic general surgeon. We want to share the video and technical points with our colleagues. AD - S. Mahmood, Hairmyres Hospital, Glasgow, United Kingdom AU - Mahmood, S. DB - Embase DO - 10.1007/s00464-017-5541-x IS - 2 KW - polyethylene terephthalate sodium chloride abdominal pain accident adult clamp colostomy diaphragm emergency follow up human iliac bone laparoscopy leukocyte count perforation peritonitis postoperative period psychiatrist sigmoid surgeon surgery vision X ray LA - English M3 - Conference Abstract N1 - L617038812 2017-07-05 PY - 2017 SN - 1432-2218 SP - S111 ST - Emergency laparoscopic repair of rectosigmoid perforation caused by toilet bursh-demage control surgery by noncolorectal laparoscopic surgeon T2 - Surgical Endoscopy and Other Interventional Techniques TI - Emergency laparoscopic repair of rectosigmoid perforation caused by toilet bursh-demage control surgery by noncolorectal laparoscopic surgeon UR - https://www.embase.com/search/results?subaction=viewrecord&id=L617038812&from=export http://dx.doi.org/10.1007/s00464-017-5541-x VL - 31 ID - 375 ER - TY - JOUR AB - Continuing concern regarding the potential health and environmental effects of depleted uranium and lead has resulted in many countries adding tungsten alloy (WA)-based munitions to their battlefield arsenals as replacements for these metals. Because the alloys used in many munitions are relatively recent additions to the list of militarily relevant metals, very little is known about the health effects of these metals after internalization as embedded shrapnel. Previous work in this laboratory developed a rodent model system that mimicked shrapnel loads seen in wounded personnel from the 1991 Persian Gulf War. In the present study, we used that system and male F344 rats, implanted intramuscularly with pellets (1 mm × 2 mm cylinders) of weapons-grade WA, to simulate shrapnel wounds. Rats were implanted with 4 (low dose) or 20 pellets (high dose) of WA. Tantalum (20 pellets) and nickel (20 pellets) served as negative and positive controls, respectively. The high-dose WA-implanted rats (n = 46) developed extremely aggressive tumors surrounding the pellets within 4-5 months after implantation. The low-dose WA-implanted rats (n = 46) and nickel-implanted rats (n = 36) also developed tumors surrounding the pellets but at a slower rate. Rats implanted with tantalum (n = 46), an inert control metal, did not develop tumors. Tumor yield was 100% in both the low- and high-dose WA groups. The tumors, characterized as high-grade pleomorphic rhabdomyosarcomas by histopathology and immunohistochemical examination, rapidly metastasized to the lung and necessitated euthanasia of the animal. Significant hematologic changes, indicative of polycythemia, were also observed in the high-dose WA-implanted rats. These changes were apparent as early as 1 month postimplantation in the high-dose WA rats, well before any overt signs of tumor development. These results point out the need for further studies investigating the health effects of tungsten and tungsten-based alloys. AD - Heavy Metals Research Team, Veterinary Sciences Department, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Ave., Bethesda, MD 20889-5603, United States Veterinary Sciences Department, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Ave., Bethesda, MD 20889-5603, United States Division of Veterinary Pathology, Walter Reed Army Institute of Research, Silver Spring, MD, United States AU - Kalinich, J. F. AU - Edmond, C. A. AU - Dalton, T. K. AU - Mog, S. R. AU - Coleman, G. D. AU - Kordell, J. E. AU - Miller, A. C. AU - McClain, D. E. DB - Scopus DO - 10.1289/ehp.7791 IS - 6 KW - Cobalt Embedded fragment Nickel Rat Rhabdomyosarcoma Tungsten Tungsten alloy M3 - Article N1 - Cited By :118 Export Date: 10 November 2020 PY - 2005 SP - 729-734 ST - Embedded weapons-grade tungsten alloy shrapnel rapidly induces metastatic high-grade rhabdomyosarcomas in F344 rats T2 - Environmental Health Perspectives TI - Embedded weapons-grade tungsten alloy shrapnel rapidly induces metastatic high-grade rhabdomyosarcomas in F344 rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-20844440546&doi=10.1289%2fehp.7791&partnerID=40&md5=1e0e031f8c3daac84067be1b4c798ca2 VL - 113 ID - 1608 ER - TY - JOUR AB - Foreign body encapsulation represents a chronic fibrotic response and has been a major obstacle that reduces the useful life of implanted biomedical devices. The precise mechanism underlying such an encapsulation is still unknown. We hypothesized that, considering its central role in many other fibrotic conditions, transforming growth factor β (TGFβ) may play an important role during the formation of foreign body capsule (FBC). In the present study, we implanted mock sensors in rats subcutaneously and excised FBC samples at day 7, 21, and 48-55 postimplantation. The most abundant TGFβ isoform in all tissues was TGFβ1, which was expressed minimally in control tissue. The expression of both TGFβ1 RNA and protein was significantly increased in FBC tissues at all time points, with the highest level in day 7 FBC. The number of cells stained for phosphorylated Smad2, an indication of activated TGFβ signaling, paralleled the expression of TGFβ. A similar dynamic change was also observed in the numbers of FBC myofibroblasts, which in response to TGFβ, differentiate from quiescent fibroblasts and synthesize collagen. Type 1 collagen, the most prominent downstream target of TGFβ in fibrosis, was found in abundance in the FBC, especially during the latter time periods. We suggest that TGFβ plays an important role in the FBC formation. Inhibition of TGFβ signaling could be a promising strategy in the prevention of FBC formation, thereby extending the useful life of subcutaneous implants. © 2007 Wiley Periodicals, Inc. AD - Department of Dermatology, Oregon Health and Science University, Portland, OR 97239, United States Department of Otolaryngology, Oregon Health and Science University, Portland, OR 97239, United States Legacy Health System, Legacy Clinical Research and Technology Center, Portland, OR 97232, United States AU - Li, A. G. AU - Quinn, M. J. AU - Siddiqui, Y. AU - Wood, M. D. AU - Federiuk, I. F. AU - Duman, H. M. AU - Ward, W. K. DB - Scopus DO - 10.1002/jbm.a.31168 IS - 2 KW - Biosensor Collagen Foreign body capsule Implantation Smad Transforming growth factor beta M3 - Article N1 - Cited By :26 Export Date: 10 November 2020 PY - 2007 SP - 498-508 ST - Elevation of transforming growth factor beta (TGFβ) and its downstream mediators in subcutaneous foreign body capsule tissue T2 - Journal of Biomedical Materials Research - Part A TI - Elevation of transforming growth factor beta (TGFβ) and its downstream mediators in subcutaneous foreign body capsule tissue UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-34447299678&doi=10.1002%2fjbm.a.31168&partnerID=40&md5=71f96439f84e9f65fa23ff0daf0759ce VL - 82 ID - 1558 ER - TY - JOUR AB - Purpose: We present our findings in a case with an intraocular foreign body in which the electroretinographic (ERG) findings were useful. Observations: A 37-year-old man was injured by an iron fragment that penetrated into his left eye through the cornea. His visual acuity was counting fingers, and a traumatic cataract prevented an examination of the fundus. B-mode ultrasonography showed a stick-like foreign body of approximately 14 mm in length in the eye. Preoperative ERGs with a contact lens electrode showed reduced responses with many blinking artifacts. Lensectomy and pars plana vitrectomy were performed and a fragment of a wire brush was seen embedded in the superior nasal retina which was removed. The decimal visual acuity improved to 1.2 two weeks later. The postoperative ERG performed with a skin electrode showed reduced responses in the injured eye. Conclusions and importance: We recommend that the physiology of the retina be assessed by recording ERGs with a skin-type electrode as soon as possible after a traumatic injury to the eye. AD - K. Shinoda, Departments of Ophthalmology, Saitama Medical University, Faculty of Medicine, Saitama, Japan, 38 Moro-Hongo Moroyama-machi, Iruma-gun, Saitama, Japan AU - Kumagai, T. AU - Matsumoto, C. S. AU - Kimura, I. AU - Shinoda, K. DB - Embase DO - 10.1016/j.ajoc.2019.100463 KW - contact lens electroretinograph skin electrode antibiotic agent iron adult article B scan best corrected visual acuity blinking case report clinical article clinical assessment computer assisted tomography cornea disease cornea injury corneoscleral wound dark adaptation electroretinogram electroretinography human intraocular foreign body intraocular pressure large intraocular iron foreign body lensectomy male medical history nasal retina pars plana vitrectomy perimetry traumatic cataract visual acuity vitreous hemorrhage RETeval LA - English M3 - Article N1 - L2001964706 2019-05-21 2019-05-23 PY - 2019 SN - 2451-9936 ST - Electroretinograms before and after extraction of large intraocular iron foreign body T2 - American Journal of Ophthalmology Case Reports TI - Electroretinograms before and after extraction of large intraocular iron foreign body UR - https://www.embase.com/search/results?subaction=viewrecord&id=L2001964706&from=export http://dx.doi.org/10.1016/j.ajoc.2019.100463 VL - 15 ID - 308 ER - TY - JOUR AD - Department of Emergency Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Taiwan Division of General Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Taiwan Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan, Taiwan AU - Hong, C. W. AU - Fan, H. L. AU - Tsai, S. H. AU - Chen, S. J. AU - Wang, J. C. DB - Scopus DO - 10.1016/j.annemergmed.2018.10.016 IS - 5 M3 - Short Survey N1 - Export Date: 10 November 2020 PY - 2019 SP - e71-e72 ST - Elderly Woman With Flank Pain T2 - Annals of Emergency Medicine TI - Elderly Woman With Flank Pain UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064695056&doi=10.1016%2fj.annemergmed.2018.10.016&partnerID=40&md5=5e8aadea6935b1e58dd33637afce70df VL - 73 ID - 1013 ER - TY - JOUR AB - Purpose: Adequate hemostasis is important for postoperative outcomes of abdominal surgery. This study evaluated the hemostatic effects and accompanying histopathological changes of a novel oxidized regenerated cellulose, SurgiGuard®, during abdominal surgery. Materials and Methods: Ten pigs underwent wedge resection of the spleen (1×1 cm) and liver (1.5×1.5 cm). The resected surface was covered with Surgicel® fabric or fibril type (Group A) or SurgiGuard® fabric or fibril type (Group B). Surgicel® and SurgiGuard® were randomized for attachment to the resected surface by fabric type (n=5) or fibril type (n=5). Blood loss was measured 5, 7, and 9 min after resection. Pigs were necropsied 6 weeks postoperatively to evaluate gross and histopathological changes. Results: There was no significant difference in total blood loss between groups [spleen fabric: Group A vs. Group B, 4.38 g (2.74-6.43) vs. 3.41 g (2.46-4.65), p=0.436; spleen fibril: Group A vs. Group B, 3.44 g (2.82-6.07) vs. 3.60 g (2.03-6.09), p=0.971; liver fabric: Group A vs. Group B, 4.51 g (2.67-10.61) vs. 6.93 g (3.09-9.95), p=0.796; liver fibril: Group A vs. Group B, 3.32 g (2.50-8.78) vs. 3.70 g (2.32-5.84), p=0.971]. Histopathological analysis revealed no significant difference in toxicities related to Surgicel® or Surgi-Guard® [inflammation, fibrosis, foreign bodies, and hemorrhage (spleen: p=0.333, 0.127, 0.751, and 1.000; liver: p=0.155, 0.751, 1.000, and 1.000, respectively)]. Conclusion: SurgiGuard® is as effective and non-toxic as Surgicel® in achieving hemostasis after porcine abdominal surgery. © Yonsei University College of Medicine 2017. AD - Departments of Hepatobiliary and Pancreatic Surgery, Yonsei University College of Medicine, Seoul, South Korea Departments of Pathology, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea Department of Quality Assurance, Samyang Biopharmaceuticals Corporation, Daejeon, South Korea Department of Research and Development, Samyang Biopharmaceuticals Corporation, Daejeon, South Korea AU - Kim, S. H. AU - Kim, S. H. AU - Yoon, H. S. AU - Kim, H. K. AU - Kim, K. S. DB - Scopus DO - 10.3349/ymj.2017.58.1.195 IS - 1 KW - Animal model Blood loss Hemostatics Histopathology Oxidized regenerated cellulose M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2017 SP - 195-205 ST - Efficacy of oxidized regenerated cellulose, SurgiGuard®, in Porcine surgery T2 - Yonsei Medical Journal TI - Efficacy of oxidized regenerated cellulose, SurgiGuard®, in Porcine surgery UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84995753807&doi=10.3349%2fymj.2017.58.1.195&partnerID=40&md5=c9c2da9c8366442ffd070cdcc85f3462 VL - 58 ID - 1161 ER - TY - JOUR AB - Objectives: To assess support discs, comprising polyethylene terephthalate (PET), coated with different polymer/levofloxacin combinations for antimicrobial activity in an animal model of infection, in order to explore the use of specific polymer coatings incorporating levofloxacin as a means of reducing device-related infections. Methods: Aliphatic polyester-polyurethanes containing different ratios of poly(lactic acid) diol and poly(caprolactone) diol were prepared, blended with levofloxacin and then used to coat support discs. The in vitro levofloxacin release profiles from these discs were measured in aqueous solution. Mice were surgically implanted with the coated discs placed subcutaneously and infection was initiated by injection of 106 cfu of Staphylococcus aureus into the subcutaneous pocket containing the implant. After 5, 10, 20 and 30 days, the discs were removed, and the number of bacteria adhering to the implant and the residual antimicrobial activity of the discs were determined. Results: In vitro, the release of levofloxacin from the coated discs occurred at a constant rate and then reached a plateau at different timepoints, depending on the polymer preparation used. In vivo, none of the discs coated with polymer blends containing levofloxacin was colonized by S. aureus, whereas 94% of the discs coated with polymer alone were infected. All discs coated with levofloxacin-blended polymers displayed residual antimicrobial activity for at least 20 days post-implantation. Conclusions: Bioerodable polyester-polyurethane polymer coatings containing levofloxacin can prevent bacterial colonization of implants in an intra-operative model of device-related infections. © The Author 2010. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. AD - Department of Microbiology and Immunology, The University of Melbourne, Parkville, VIC 3010, Australia Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, VIC 3052, Australia Australian Commonwealth Scientific and Industrial Research Organisation, Clayton, VIC 3168, Australia Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia Royal Victorian Eye and Ear Hospital, East Melbourne, VIC 3002, Australia Bionic Ear Institute, East Melbourne, VIC 3002, Australia Bionic Technologies Australia, East Melbourne, VIC 3002, Australia AU - Hart, E. AU - Azzopardi, K. AU - Taing, H. AU - Graichen, F. AU - Jeffery, J. AU - Mayadunne, R. AU - Wickramaratna, M. AU - O'Shea, M. AU - Nijagal, B. AU - Watkinson, R. AU - O'Leary, S. AU - Finnin, B. AU - Tait, R. AU - Robins-Browne, R. C7 - dkq057 DB - Scopus DO - 10.1093/jac/dkq057 IS - 5 KW - Implant-associated infections Levofloxacin Staphylococcus aureus M3 - Article N1 - Cited By :32 Export Date: 10 November 2020 PY - 2010 SP - 974-980 ST - Efficacy of antimicrobial polymer coatings in an animal model of bacterial infection associated with foreign body implants T2 - Journal of Antimicrobial Chemotherapy TI - Efficacy of antimicrobial polymer coatings in an animal model of bacterial infection associated with foreign body implants UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77953723684&doi=10.1093%2fjac%2fdkq057&partnerID=40&md5=155b2f79c0f50deab18ffaff650c4789 VL - 65 ID - 1465 ER - TY - JOUR AB - Introduction and Aim of the Study: Bulking therapy has been developed since the beginning of the 20th century with the aim to increase urethral coaptation and hence restore continence. The ideal agent is not absorbable, causes no immunological or inflammatory reaction, does not stimulate fibrosis, is not toxic, does not migrate (i.e. has a particle diameter of >80 mm), and has viscosity and cohesiveness that allow easy injection. The materials studied to date have varying success rates that leave space for improvement. In this study we evaluate the safety and efficacy of transurethral injectionwith Bulkamid (hydrogel cross-linked with polyacrylamide - PAHG) for treating women with urodynamic stress urinary incontinence (SUI). Materials and Methods: Between March 2008 and May 2009, 48 women with urodynamic SUI were treated with transurethral Bulkamid injection. Median age was 65.5 (interquartile range: 54.75-70.75 years). The women were evaluated at baseline with a history, physical examination, evaluation of the urethral mobility using trans-labial ultrasound, urine dipstick test, a micturition diary, daily pad count, 24-h padweight test for 3 days, Personal Global Impression of Severity Questionnaire (PGI-S) and International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF). Urodynamic evaluation was performed including spontaneous uroflowmetry, PVR measurement, urethral pressure profilometry and water cystometry while seated (filling rate 50 ml/min) followed by a pressure-flow study. The injection was given under local anaesthesia (5 ml of 5%lidocaine).With thewoman in the lithotomy position, Bulkamid (2 ml) was injected transurethrally into the submucosa using a 23 G needle and a special cystoscope that can be rotated of almost 360 (Bulkamid Urethral Bulking System) (Fig. 1). The deposits were placed 0.5- 1 cm distal to the bladder neck at 3, 6 and 9 o'clock. After satisfactory urethral occlusion, the bladder was emptied via a 10 ch catheter. Before injection, the women received prophylactic antibiotics, and they were discharged the day after surgery after successful voiding (PVR <50 ml, assessed using ultrasonography). Patients were re-evaluated 1, 3, 6, 12 and 18 months later. The efficacy was estimated by daily pad count, 24-h pad-weighing test for 3 days, ICIQ-SF and Personal Global Impression of Improvement Questionnaire (PGI-I). Results: All patients were affected by urodynamic SUI. In 9 cases (19%) trans-labial ultrasound showed urethral hypermobility. Sixteen (33%) patients reported previous pelvic floor rehabilitation and 22 (46%) had undergone pelvic surgery for organ prolapse or incontinence. At baseline the median number of pads was 4 (range 1-16), the median urine leakage/ 24 h was <50 g in 14 patients (29%), 50 < 250 g in 8 (17%) and >250 g in 26 (54%). The median maximum urethral closure pressure (MCPU)was 42 cmH20 (interquartile range: 34,25-60) and median Valsalva leak point pressure (VLPP) 47 cmH20 (I-III quartile 39,5-60). Eleven (23%) patients had detrusor overactivity before injection.Median PGI-S score was 4 and ICIQ-SF score was 16,5. The mean volume of Bulkamid injected was 2ml (range 1-4 ml) per session. Forty-four women (92%) received 2ml of Bulkamid, three patients (6%) were injected with 4ml to obtain a satisfactory urethral occlusion, in one patient (2%) the urethral occlusion was obtained with 1 ml. Two patients (4%)were re-injected after the 3-month follow-up visit because of insufficient effect. Mean follow-up was 11 months (interquartile range: 9-17). No patients were lost at follow-up.All patients completed at least 6months of followup, 23 completed at least 12 months of follow-up and 11 completed 18 months of follow-up after the last injection. At follow-up 36 (75%) patients were found to be dry (i.e. 0-1 safety pad) or significantly improved (i.e. >50% reduction in daily pad usage and pad test result with a PGI-I Score of 1-2), twelve (25%) demonstrated no improvement (i.e. <50% reduction in daily pad usage and pad test result with a PGI-I Score of 3-4). In the ntire cohort of patients the median number of pads/24 hwas significantly reduced after treatment from 4 pads/day to 1 pad/day (P < 0,001) (Fig. 2) and the median ICQ-SF score decreased significantly after treatment from 16,5 to 7,5 (P < 0,001) (Fig. 3). These results are stable at 12 months of follow-up. The most common adverse event was postoperative urinary retention (14 patients, 29%), treated by self-catheterization. Forty-four women (92%) were discharged the day after the injection. (Graph presented) Interpretation of Results: Polyacrylamides have been used for more than 10 years in plastic surgery and in themanufacture of contact lenses.1 No adverse events related to the composition of the implant have been reported to date. Polyacrylamides are atoxic due to their resistance to biodegradation and because their large molecular size prevents them from passing biological membranes; they show good elasticity as a soft-tissue filler, they arewell accepted by human tissue and foreign-body reaction is either absent or minimal.2 Bulkamid is a biocompatible and non-absorbable hydrogel consisting of 97.5%water and 2.5% cross-linked polyacrylamide. The hydrogel exchanges water with the surrounding tissue. The visco-elastic properties are optimized for urethral bulking. Bulkamid is homogeneous as it does not contain any particles (micro balls, micro crystals and the suchlike), so there is no tissue hardening or other impairment to the urethral function. The procedure is minimally invasive and is performed under endoscopic control to ensure correct placement of the bulking agent.3 Our preferred indication is Intrinsic Sphincter Deficiency (ISD) with fixed urethra, but it is our opinion that the procedure may be proposed in all patients affected by urodynamic SUI with or without urethral hypermobility, after an assessment of the risks and benefits, especially when a minimally invasive procedure is desired. In our experience there was a subjective success rate of 75% with only minor complications, the most prevalent ofwhich was retention. These results aremaintained at mid follow-up. Conclusions: This study provides evidence that Bulkamid can be a safe and efficacy bulking agent for treating SUI. AD - B. Giovanni, S.C. Neuro-Urologia, ASO CTO-M. Adelaide, Torino, Italy AU - Giovanni, B. AU - Paola, B. AU - Luisella, S. AU - Mario, V. AU - Roberto, C. AU - Alessandro, G. DB - Embase DO - 10.1002/nau.20930 KW - polyacrylamide water bulking agent lidocaine antibiotic agent female hydrogel safety stress incontinence patient follow up injection questionnaire occlusion urine ultrasound incontinence tissues membrane elasticity soft tissue human tissue foreign body reaction crystal sphincter urethra risk minimally invasive procedure continence inflammation fibrosis viscosity physical examination micturition consultation uroflowmetry cystometry local anesthesia lithotomy position submucosa needle cystoscope bladder neck therapy bladder catheter surgery echography pelvis floor rehabilitation pelvis surgery tissue injury overactive bladder urine retention catheterization contact lens implant biodegradation molecular size plastic surgery LA - English M3 - Conference Abstract N1 - L70428659 2011-06-04 PY - 2010 SN - 0733-2467 SP - 107-108 ST - Efficacy and safety of polyacrylamide hydrogel (Bulkamid1) for treating stress urinary incontinence in women: A single centre study T2 - Neurourology and Urodynamics TI - Efficacy and safety of polyacrylamide hydrogel (Bulkamid1) for treating stress urinary incontinence in women: A single centre study UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70428659&from=export http://dx.doi.org/10.1002/nau.20930 VL - 29 ID - 564 ER - TY - JOUR AB - The present study examined the effects of steroids and lubricants on electrical impedance and tissue response following cochlear implantation in animal models. Guinea pigs were implanted following either no treatment, or intrascalar injection with dexamethasone, triamcinolone, sodium hyaluronate or saline. Cats were implanted following either no treatment, or intrascalar injection with dexamethasone, triamcinolone or a mixture of triamcinolone with sodium hyaluronate. In guinea pigs, impedance changes and intracochlear tissue response were less for the hyaluronate and saline groups. In cats, impedance in the dexamethasone group increased similar to non-treated cats. Impedance of triamcinolone treated cats remained low for about two months after implantation, before increasing to levels similar to the other groups. Significant fibrous tissue growth was observed histologically. The results of the present study indicate that a single intracochlear application of hyaluronate or triamcinolone may postpone, but will ultimately not prevent the rise in impedance following cochlear implantation. Copyright © 2007 John Wiley & Sons, Ltd. AD - Co-operative Research Centre (CRC) for Cochlear Implant and Hearing Aid Innovation, 384-388 Albert Street, East Melbourne, VIC 3002, Australia AU - Huang, C. Q. AU - Tykocinski, M. AU - Stathopoulos, D. AU - Cowan, R. DB - Scopus DO - 10.1002/cii.336 IS - 3 KW - Cochlear implantation Fibrous tissue growth Impedance Intracochlear electrodes M3 - Article N1 - Cited By :39 Export Date: 10 November 2020 PY - 2007 SP - 123-147 ST - Effects of steroids and lubricants on electrical impedance and tissue response following cochlear implantation T2 - Cochlear Implants International TI - Effects of steroids and lubricants on electrical impedance and tissue response following cochlear implantation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-34848841188&doi=10.1002%2fcii.336&partnerID=40&md5=94960dac3836c56e2145990a1e7933a9 VL - 8 ID - 1551 ER - TY - JOUR AB - Objective. To evaluate the effects of NasoPore after packing of the middle ear in guinea pigs. Study Design. A randomized, prospective, controlled animal study. Setting. University laboratory. Subjects and Methods. Forty-one guinea pigs were divided into 3 groups. In group 1 (n = 12), the middle ears of animals were unilaterally implanted with NasoPore, leaving the contralateral middle ears packed with absorbable gelatin sponge soaked in a solution containing kanamycin and furosemide as an ototoxicity-positive control; group 2 (n = 17) underwent the same experimental protocol as group 1, except the gelatin sponge was unsoaked; in group 3 (n = 12), NasoPore was inserted unilaterally and no packing material was placed into the contralateral ear. Auditory brainstem responses (ABRs) were performed preoperatively and 3 months after the procedure. The surface preparation and scanning electron microscopy (SEM) were assessed 3 months postoperatively, whereas pathology of middle ear was analyzed in 5 samples of group 2. Results. ABR thresholds of the contralateral ear significantly increased in group 1 and were slightly shifted in group 2 compared with the NasoPore-packed and nonpacked ears 3 months postoperatively. The NasoPore-packed middle ears were found to have less fibrosis and inflammation and less thickened bone and tympanic membranes than Gelfoam-packed ears. Surface preparations and SEM showed no ototoxicity in the inner ear of NasoPore-packed ears. Conclusion. NasoPore appears to be effective for use in otosurgery. It caused less fibrosis in the middle ear than conventional packing agents and no ototoxicity to the inner ear. © American Academy of Otolaryngology - Head and Neck Surgery Foundation 2011. AD - Otorhinolaryngology Hospital, First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan Road II, Guangzhou, Guangdong, China AU - Huang, G. AU - Chen, X. AU - Jiang, H. DB - Scopus DO - 10.1177/0194599811400834 IS - 1 KW - Guinea pig Inner ear Middle ear NasoPore Ototoxicity M3 - Article N1 - Cited By :10 Export Date: 10 November 2020 PY - 2011 SP - 131-136 ST - Effects of NasoPore packing in the middle ear cavity of the guinea pig T2 - Otolaryngology - Head and Neck Surgery TI - Effects of NasoPore packing in the middle ear cavity of the guinea pig UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-80052094335&doi=10.1177%2f0194599811400834&partnerID=40&md5=7c29260b7f0dc2b6fb1602cdc4ed44e5 VL - 145 ID - 1415 ER - TY - JOUR AB - PURPOSE. To evaluate and compare the effectiveness of two adhesion barriers, Interceed and Seprafilm, on wound healing reaction after glaucoma filtration surgery. MATERIALS AND METHODS. Full-thickness filtration surgery was carried out on three groups, each containing four rabbits. Interceed and Seprafilm prepared in 3x4 mm dimensions was put on and around scleral opening in Groups 1 and 2, respectively. All groups received tobramycin and dexamethasone drops tid for 14 days. Intraocular pressure (IOP), anterior chamber depth, and bleb appearance were checked on the first, third, seventh, and 14th days. The rabbits were killed on the 14th day and the trabeculectomy area with overlying conjunctiva was excised. The samples were fixed with 10% formalin, buried in paraffin, and stained with hematoxylin and eosin. The surgical site and surrounding subconjunctival area were evaluated histopathologically for cell counts (fibroblast, lymphocyte, eosinophil, and macrophage), presence of edema and foreign body reaction, and potency of the fistula tract. RESULTS. Mean IOP at the first and third day examinations was significantly different between groups, but there was no statistically significant difference among the groups with respect to IOP, anterior chamber depth, or bleb appearance at the seventh and 14th days. The groups were similar with respect to number of fibroblasts, eosinophils, and neutrophils. Number of macrophages was significantly increased in Groups 1 and 2 and number of vessels was significantly decreased in Group 1. CONCLUSIONS. Neither of these two adhesion-preventing substances seems to suppress wound healing reaction after glaucoma filtration surgery. However, a diminished wound healing reaction was expected with a decreased number of vessels, such as in Group 1. Increased number of macrophages in both groups may result in a decreased level of some inflammatory mediators. © Wichtig Editore, 2005. AD - Ophthalmology Department, Firat University School of Medicine, Elazig, Turkey Pathology Department, Firat University School of Medicine, Elazig, Turkey Firat University, Ophthalmology Department, Firat Tip Merkezi, Elazig, Turkey AU - Akyol, N. AU - Aydogan, S. AU - Akpolat, N. DB - Scopus DO - 10.1177/112067210501500509 IS - 5 KW - Filtration surgery Interceed Seprafilm Wound healing M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2005 SP - 591-597 ST - Effects of membrane adhesion barriers on wound healing reaction after glaucoma filtration surgery: A comparative study with Interceed and Seprafilm T2 - European Journal of Ophthalmology TI - Effects of membrane adhesion barriers on wound healing reaction after glaucoma filtration surgery: A comparative study with Interceed and Seprafilm UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-26444610082&doi=10.1177%2f112067210501500509&partnerID=40&md5=b0a2fa7246a6f08f81cef13ee9e0d1cf VL - 15 ID - 1617 ER - TY - JOUR AB - Background: Decreased tear production has been reported in<1.0% of the general population but in 20-39% in HIV-positive individuals. The incidence of the dry-eye syndrome (DES) under HAART remains unchanged compared to the incidence in the pre-HAART era. DES, likely caused either by HIV itself and HAART, is a tear film alteration involving both lipid and mucous lacrimal layers. Usually DES is treated with tear drops (ipromellosa or ialuronic acid) to avoid further corneal alterations. A new compound, lipoic acid, featured with antioxidant, epitheliotropic and neurotropic characteristics was evaluated in a eye drop association with ipromellosa in HIV-positive patients. Methods: This study (prospective, randomized, controlled, single blinded) assessed the effect of ipromellosa plus lipoic acid (group A) versus ipromellosa only (group B) eye drops on DES in HIV-positive patients. Patients were enrolled if complaining any eye drynessassociated symptom (burning, itching, foreign body sensation, photophobia) and hyperaemia. We excluded patients with infectious kerato-conjunctivitis, ocular inflammation, erosions and corneal ulcers, severe systemic comorbidities or previous surgery in anterior or posterior segment in the last 6 months. One drop of the randomized preparation was given in each eye three times a day for 3 months. The evaluation consisted in: physical examination, biomicroscopic exam, visual acuity, Schirmer test and tear break-up time test (BUT) measured in both eyes. Questionnaire about dry-eye symptoms and quantitative tests have been performed in baseline visit, then at 15, 30 and 90 days. Results: Eighteen patients (36 eyes) were randomized but only 32 eyes were analyzed. The demographic characteristics were similar in two groups. Mean age was 43 years (range 28-56), males were 11. All patients were on combination antiretroviral therapy (cART), HIVRNA was undetectable and median CD4 cell counts was 421 cells/ll (range 133-720). BUT improved significantly in group A versus B (at baseline: 5 s ± 2 and 6.17 s ± 1.60; after 90 days: 10.2 s ± 1.48 and 7 s ± 1.9, respectively, p = 0.01). Photophobia and hyperaemia also improved in a significant way (p = 0.03 for both parameters) in the group A versus B at the 3-month evaluation. A significant trend favouring group A was noted for other symptoms. The immune status as measured by CD4+ cell count and percentage did not changed during the observational period. Discussion: Patients treated with lipoic acid-containing eye drops showed a significant improvement in their inflammatory process when compared to a control treatment. This may be due to a quick stabilization of lacrimal film (already present at 15 days), irrespective of immune-virological status. Although the number of patients was limited, our results confirmed the epithelio-neuroprotective activity and epithelio-neurotropic, anti-oxidant functions of lipoic acid. AD - A. Uglietti, Clinica Malattie Infettive, Fondazione IRCCS, Policlinico San Matteo, Pavia, Italy AU - Uglietti, A. AU - Pezzotta, S. AU - Antoniazzi, E. AU - Maserati, R. DB - Embase DO - 10.1007/s15010-011-0090-z KW - thioctic acid eye drops CD4 antigen acid antioxidant oxidizing agent lipid Human immunodeficiency virus Human immunodeficiency virus infected patient Retroviridae acquired immune deficiency syndrome patient eye highly active antiretroviral therapy lacrimal fluid dry eye cell count photophobia hyperemia pruritus foreign body sensation keratoconjunctivitis cornea ulcer surgery physical examination visual acuity Schirmer test questionnaire demography male therapy immune status inflammation population tear film eye inflammation LA - English M3 - Conference Abstract N1 - L70389949 2011-04-22 PY - 2011 SN - 0300-8126 SP - S74 ST - The effects of lipoic acid eye drops in HIV-positive patients T2 - Infection TI - The effects of lipoic acid eye drops in HIV-positive patients UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70389949&from=export http://dx.doi.org/10.1007/s15010-011-0090-z VL - 39 ID - 545 ER - TY - JOUR AB - Purpose: Long term results after surgical treatment of disc herniation have shown that epidural and/or peridural fibrosis formed during the healing process after surgical intervention. We conducted this experimental study to evaluation of the effectiveness of the bioresorbable barriers (ADCON-L and Seprafilm ® Adhesion Barrier) on formation of the peridural fibrosis in rat model performed laminectomy. Methods: Thirty-two male Wistar albino rats 250-350 g body weight were distributed into three groups (CONTROL, AL group received ADCON-L; SAB group received Seprafilm ® Adhesion Barrier). A dorsal laminectomy at L3, L4, L5 was performed, and then except those of the CONTROL group, the experimental material was left on the dura mater. Six weeks later spinal column of all rats was totally removed between the T10 and L5 levels, and peridural fibrosis, and dural adhesions were evaluated histologically and graded. The results were compared statistically by using the chi-square (χ 2) test. Also three random regions were examined, and the fibroblast cells were counted. The fibroblast count results were statistically analysed by using the One-Way ANOVA test. Results: The variation of histopathological grades was statistically significant regarding the comparison of the all groups obtained from the χ 2 test (χ 2 = 16.40; p = 0.003). However, the variation in the mean values of the fibroblast count result was not statistically significant obtained from the One-Way ANOVA test (F = 2.114; p > 0.05). Conclusion: Our study results suggest that Seprafilm ® Adhesion Barrier and ADCON-L can be effective in reducing the prevalence of the postoperative peridural adhesions in rat laminectomy model. On the other hand, the fibroblast densities of the experimental groups were not different between groups. So, we could say that these materials can act as a foreign body in long term period in rat. © 2010 Elsevier Ltd. AD - Kirikkale University, Faculty of Medicine, Department of Neurosurgery, 71100 Kirikkale, Turkey Mersin University, Faculty of Medicine, Department of Histology and Embriology, Mersin, Turkey Ufuk University, Faculty of Arts and Sciences, Department of Statistics, Ankara, Turkey AU - Kasimcan, M. O. AU - Bakar, B. AU - Akta, S. AU - Alhan, A. AU - Yilmaz, M. DB - Scopus DO - 10.1016/j.injury.2010.12.017 IS - 8 KW - Adhesion barrier Fibroblast Peridural fibrosis Spine M3 - Article N1 - Cited By :49 Export Date: 10 November 2020 PY - 2011 SP - 778-781 ST - Effectiveness of the biophysical barriers on the peridural fibrosis of a postlaminectomy rat model: An experimental research T2 - Injury TI - Effectiveness of the biophysical barriers on the peridural fibrosis of a postlaminectomy rat model: An experimental research UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79960011478&doi=10.1016%2fj.injury.2010.12.017&partnerID=40&md5=347be675930010a0fa07e49860439421 VL - 42 ID - 1411 ER - TY - JOUR AB - BACKGROUND: Despite rigorous manual counting protocols and the classification of retained surgical items (RSIs) as potential "never events," RSIs continue to occur in approximately 1 per 1,000 to 18,000 operations. This study's goals were to evaluate the incorporation of a radiofrequency detection system (RFDS) into existing laparotomy sponge- and Raytec-counting protocols for the detection of RSIs and define associated risk factors. STUDY DESIGN: All patients undergoing surgery at the University of North Carolina Hospitals from September 2009 to August 2010 were enrolled consecutively. The performance of an RFDS-incorporated accounting protocol for detecting RSIs was prospectively evaluated. Several operative metrics were recorded to identify risk factors for miscounts. RESULTS: A total of 2,285 patients were enrolled. One near miss was detected by the RFDS. Thirty-five miscounts occurred, for a rate of 1.53%. The ultimate locations of miscounted items were surgical site (n = 11), within operative suite (n = 10), surgical drapes (n = 2), and emergency protocol deviations (n = 12). Perioperative variables associated with miscounts were higher estimated volume of blood lost, longer operations, higher number of laparotomy sponges used, open surgical approach, "after hours" operations, change of surgical team during operation, weekend or holiday operations, unanticipated changes in operative plan during surgery, and emergency operations. Body mass index was not associated with miscounts. Surveys completed by participating surgical staff suggested high confidence in the RFDS for prevention of RSIs. CONCLUSIONS: The incorporation of the RFDS assisted in the resolution of a near-miss event (1 of 2,285) not detected by manual counting protocols and assisted in the resolution of 35 surgical-sponge miscounts. No known RSIs occurred during the study period. Risk factors for miscounts were identified and can help identify at-risk surgical populations. AD - University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA. crupp@med.unc.edu AN - 22770865 AU - Rupp, C. C. AU - Kagarise, M. J. AU - Nelson, S. M. AU - Deal, A. M. AU - Phillips, S. AU - Chadwick, J. AU - Petty, T. AU - Meyer, A. A. AU - Kim, H. J. DA - Oct DO - 10.1016/j.jamcollsurg.2012.06.014 DP - NLM ET - 2012/07/10 IS - 4 KW - Equipment Design Female Foreign Bodies/*diagnosis/*prevention & control Humans Male Middle Aged Prospective Studies *Radio Waves *Surgical Sponges LA - eng N1 - 1879-1190 Rupp, Christopher C Kagarise, Mary J Nelson, Stella M Deal, Allison M Phillips, Susan Chadwick, Janet Petty, Tamara Meyer, Anthony A Kim, Hong Jin Clinical Trial Journal Article United States J Am Coll Surg. 2012 Oct;215(4):524-33. doi: 10.1016/j.jamcollsurg.2012.06.014. Epub 2012 Jul 6. PY - 2012 SN - 1072-7515 SP - 524-33 ST - Effectiveness of a radiofrequency detection system as an adjunct to manual counting protocols for tracking surgical sponges: a prospective trial of 2,285 patients T2 - J Am Coll Surg TI - Effectiveness of a radiofrequency detection system as an adjunct to manual counting protocols for tracking surgical sponges: a prospective trial of 2,285 patients VL - 215 ID - 127 ER - TY - JOUR AB - Ventricular assist devices (VADs) are an effective bridging or destination therapy for patients with advanced stage heart failure. These devices remain susceptible to adverse events including infection, bleeding, and thrombus; events linked to the foreign body response. Therefore, the biocompatibility of all biomaterials used is crucial to the success of medical devices. Biomaterials common in VADs—DLC: diamond-like carbon coated stainless steel; Sap: single-crystal sapphire; SiN: silicon nitride; Ti: titanium alloy; and ZTA: zirconia-toughened alumina—were tested for their biocompatibility through incubation with whole human blood for 2 h with mild agitation. Blood was then removed and used for: complete cell counts; leukocyte activation and death, and the production of key inflammatory cytokines. All were compared to time 0 and an un-exposed 2 h sample. Monocyte numbers were lower after exposure to DLC, SiN, and ZTA and monocytes showed evidence of activation with DLC, Sap, and SiN. Neutrophils and lymphocytes were unaffected. This approach allows comprehensive analysis of the potential blood damaging effects of biomaterials. Monocyte activation by DLC, Sap, ZTA, and SiN warrants further investigation linking effects on this cell type to unfavorable inflammatory/thrombogenic responses to VADs and other blood handling devices. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 1730–1738, 2018. AD - C.A. Thornton, Institute of Life Science, Swansea University Medical School, Swansea, United Kingdom AU - Radley, G. AU - Pieper, I. L. AU - Thornton, C. A. DB - Embase Medline DO - 10.1002/jbm.b.33981 IS - 5 KW - ventricular assist device biomaterial CD11b antigen CD14 antigen CD15 antigen diamond like carbon coated stainless steel formyl peptide receptor 1 formylpeptide receptor interleukin 1beta interleukin 6 interleukin 8 L selectin silicon nitride single crystal sapphire titanium tumor necrosis factor unclassified drug zirconia toughened alumina adult apoptosis article biocompatibility blood CD3+ T lymphocyte controlled study cytokine production human human cell inflammation leukocyte leukocyte activation leukocyte count lymphocyte monocyte monocyte count neutrophil normal human physical parameters roughness surface area thrombocyte aggregation LA - English M3 - Article N1 - L618239961 2017-09-15 2018-06-28 PY - 2018 SN - 1552-4981 1552-4973 SP - 1730-1738 ST - The effect of ventricular assist device-associated biomaterials on human blood leukocytes T2 - Journal of Biomedical Materials Research - Part B Applied Biomaterials TI - The effect of ventricular assist device-associated biomaterials on human blood leukocytes UR - https://www.embase.com/search/results?subaction=viewrecord&id=L618239961&from=export http://dx.doi.org/10.1002/jbm.b.33981 VL - 106 ID - 340 ER - TY - JOUR AB - Purpose: To evaluate the effects of red propolis on cheek pouch angiogenesis in a hamster new model sponge implant. Methods: Forty eight animals divided into eight groups. (Groups I-IV), the animals were treated for 15 days before and 10 days after sponge implantation. (Groups V-VIII), the animals were treated for 10 days after sponge implantation (GI and GV: red propolis 100 mg/kg, GII and GVI: celecoxib 20 mg/kg, GIII and GVII: 1% gum arabic 5 mL/kg, GIV and GVIII: distilled water 5 mL/kg). On the 11th day of implantation, the animals were anesthetized for stereoscopic microscopic imaging and morphometric quantification of angiogenesis (SQAN), followed by histopathological evaluation (H&E). Results: In the SQAN analysis, no significant difference was found between the groups. However, on histology, propolis was found reduce the population of mastocytes in the qualitative analyses (p = 0,013) in the quantitative analyses to reduce the number of blood vessels (p = 0,007), and increase the macrophage count (p = 0,001). Conclusion: Red propolis inhibited inflammatory angiogenesis when administered before andcontinuously after sponge implant, and was shown to have immunomodulating effects on inflammatory cells (mastocytes and macrophages) in a new sponge implant hamster model. © 2018, Sociedade Brasileira para o Desenvolvimento de Pesquisa em Cirurgia. All rights reserved. AD - School of Medicine, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil UFC, Fortaleza, CE, Brazil Department of Organic and Inorganic Chemistry, UFC, Fortaleza, CE, Brazil AU - Melo, N. O. R. AU - Juanes, C. C. AU - Alves, M. F. A. AU - Silva, E. T. M. AU - Jamacaru, F. V. F. AU - de Lemos, T. L. G. AU - Dornelas, C. A. DB - Scopus DO - 10.1590/s0102-865020180050000004 IS - 5 KW - Angiogenesis Inhibitors Cricetinae Inflammation Mesocricetus Propolis M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2018 SP - 420-430 ST - Effect of red propolis on hamster cheek pouch angiogenesis in a new sponge implant model T2 - Acta Cirurgica Brasileira TI - Effect of red propolis on hamster cheek pouch angiogenesis in a new sponge implant model UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048675269&doi=10.1590%2fs0102-865020180050000004&partnerID=40&md5=7bd08ca5630e49945a3a549795625986 VL - 33 ID - 1079 ER - TY - JOUR AB - Retained surgical items (eg, sponges, instruments) remain the most frequently reported sentinel events. The primary strategy for preventing retained sponges is the sponge count. Reconciling sponge counts is time consuming and can extend the duration of operative and other invasive procedures. The primary objective of this observational study was to evaluate the effect of a radiofrequency (RF) surgical-sponge detection system on time spent searching for surgical sponges. The study included 27,637 procedures during nine months before and after implementing an RF surgical-sponge detection system. After implementation of the system, time spent searching for sponges was reduced by 79.58%, the percentage of unreconciled counts was reduced by 71.28%, and time spent using radiography to rule out a retained sponge was reduced by 46.31%. This resulted in a reduction of costs. These findings should be used as part of a comprehensive cost analysis of alternative methods when evaluating RF sponge detection technology. AN - 31135978 AU - Steelman, V. M. AU - Schaapveld, A. G. AU - Storm, H. E. AU - Perkhounkova, Y. AU - Shane, D. M. DA - Jun DO - 10.1002/aorn.12698 DP - NLM ET - 2019/05/29 IS - 6 KW - Foreign Bodies/*diagnostic imaging/epidemiology/*prevention & control Humans Postoperative Complications/prevention & control Radio Frequency Identification Device/*methods *Sentinel Surveillance Surgical Sponges *radiofrequency *retained surgical item *sponge count *sponge detection *unreconciled count LA - eng N1 - 1878-0369 Steelman, Victoria M Schaapveld, Ann G Storm, Hillary E Perkhounkova, Yelena Shane, Dan M Journal Article Observational Study Research Support, Non-U.S. Gov't United States AORN J. 2019 Jun;109(6):718-727. doi: 10.1002/aorn.12698. PY - 2019 SN - 0001-2092 SP - 718-727 ST - The Effect of Radiofrequency Technology on Time Spent Searching for Surgical Sponges and Associated Costs T2 - Aorn j TI - The Effect of Radiofrequency Technology on Time Spent Searching for Surgical Sponges and Associated Costs VL - 109 ID - 232 ER - TY - JOUR AB - Several experiments were performed to compare the in vitro adhesion of human macrophage and granulocyte inflammatory cells to polyethylene terephthalate substrate and the same coated with a phosphorylcholine (PC)-based polymer. The inclusion of various types of serum at different stages in the assay indicated that protein adsorption and passivation of the surface may be responsible for reducing the number of inflammatory cells adhering to the uncoated polyethylene terephthalate controls. In all of the assays performed there was a statistically significant reduction (p < 0.05; analysis of variance) of the number of inflammatory cells adhering to the PC-coated samples, linked to the ability of these surfaces to resist protein adhesion. Implantations of PC-coated stainless steel and high-density polyethylene USP control samples were made in a rabbit intramuscular model. Histological examination of the number of inflammatory cells present around the implant sites 4 weeks postimplantation showed there were 40% less cells associated with the PC-coated samples compared with control, but this was not statistically significant. Fibrous capsule thickness, however, whereas marginally less at 4 weeks, had almost completely regressed for the PC-coated sample at 13 weeks post-implantation and was statistically thinner (p < 0.01; Mann-Whitney U test) than the high-density polyethylene USP control. These findings support the view that low biointeractions observed for PC-based technology in vitro can result in reduced inflammation and foreign body reaction in vivo. © 2003 Wiley Periodicals, Inc. AD - Biocompatibles UK Ltd., Farnham Business Park, Weydon Lane, Farnham, Surrey, GU9 8QL, United Kingdom Biomedical Materials Research Group, Sch. of Pharm. and Biomol. Sciences, University of Brighton, Moulsecoomb, Brighton, BN2 4GJ, United Kingdom AU - Goreish, H. H. AU - Lewis, A. L. AU - Rose, S. AU - Lloyd, A. W. DB - Scopus DO - 10.1002/jbm.a.10141 IS - 1 KW - Cellular adhesion Fibrous capsule formation Inflammatory response Phosphorylcholine polymer coating M3 - Article N1 - Cited By :52 Export Date: 10 November 2020 PY - 2004 SP - 1-9 ST - The effect of phosphorylcholine-coated materials on the inflammatory response and fibrous capsule formation: In vitro and in vivo observations T2 - Journal of Biomedical Materials Research - Part A TI - The effect of phosphorylcholine-coated materials on the inflammatory response and fibrous capsule formation: In vitro and in vivo observations UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0347596754&doi=10.1002%2fjbm.a.10141&partnerID=40&md5=984f3ec51ec25cc89e44f26c9f54e21c VL - 68 ID - 1636 ER - TY - JOUR AB - Cardiopulmonary bypass (CPB) produces an inflammatory response due to the interaction of blood with a foreign body surface. The lungs are most affected by this inflammatory response. Pentoxifylline (PTX), a phosphodiesterase inhibitor and an inhibitor of leukocyte activation, is used to minimize damage in lungs where leukocytes play an important role. Twenty patients with mitral valve stenosis with planned mitral valve surgery were included in the study. The ten patients receiving pentoxifylline (PTX group) were administered 400 mg PTX orally TID for 3 days preoperatively and, following anesthetic induction, a 300 mg PTX infusion was given. The ten patients receiving no PTX were the control group (CT). Platelet and leukocyte counts, mean pulmonary arterial pressure (mPAP), pulmonary capillary wedge pressure (PCWP), cardiac index (CI), pulmonary vascular resistance (PVR), alveolar-arterial PO2 gradient (AaDO2) were measured just before and after CPB, and 2 h postoperatively. The number of the leukocytes increased in the blood samples drawn 15 min after CPB in both groups and 2 h postoperatively showed no statistical change. The number of platelets had decreased significantly at the end of the CPB in both groups and, 2 h postoperatively, there was a further decrease in the blood count in the control group (P < 0.05). There was no significant difference in either the preoperative or postoperative PAP, PAWP, and CI. Pulmonary vascular resistance increased in both groups following the CPB (CT, before: 136 +/- 44, after: 177 +/- 94 dyne. sec.cm-5; PTX, before: 151 +/- 82, after 182 +/- 43 dynes.sec.cm-5). Two hours postoperatively, a considerable increase continued in the control group (CT 219 +/- 170 dynes.sec. cm-5), while there was an insignificant increase in the PTX group (PTX 193 +/- 51 dynes.sec.cm-5) (P < 0.05). The alveolar-arterial PO2 gradient increased after the CPB in both groups but a moderate decrease was observed 2 h postoperatively. In lung biopsy specimens taken before and after the CPB, there was marked leukocyte sequestration in the control group, whereas the number of leukocytes was seen to be insignificant in the PTX group (P < 0.005). This dosage regimen of PTX inhibits the postoperative increase in PVR and greatly minimized leukocyte sequestration in the lung due to CPB. AD - Department of Cardiovascular Surgery, Izmir State Hospital, Turkey. AN - 8737690 AU - Türköz, R. AU - Yörükoğlu, K. AU - Akcay, A. AU - Yilik, L. AU - Baltalarli, A. AU - Karahan, N. AU - Adanir, T. AU - Sağban, M. DO - 10.1016/s1010-7940(96)80092-3 DP - NLM ET - 1996/01/01 IS - 5 KW - Adult *Cardiopulmonary Bypass Dose-Response Relationship, Drug Drug Administration Schedule Female Foreign-Body Reaction/immunology/*prevention & control Hemodynamics/drug effects Humans Leukocyte Count/drug effects Lung/blood supply Male Middle Aged Mitral Valve Stenosis/immunology/*surgery Neutrophils/drug effects/immunology Pentoxifylline/*administration & dosage Phosphodiesterase Inhibitors/*administration & dosage Platelet Count/drug effects Premedication Pulmonary Alveoli/immunology Systemic Inflammatory Response Syndrome/immunology/*prevention & control Vascular Resistance/drug effects/immunology LA - eng N1 - Türköz, R Yörükoğlu, K Akcay, A Yilik, L Baltalarli, A Karahan, N Adanir, T Sağban, M Clinical Trial Controlled Clinical Trial Journal Article Germany Eur J Cardiothorac Surg. 1996;10(5):339-46. doi: 10.1016/s1010-7940(96)80092-3. PY - 1996 SN - 1010-7940 (Print) 1010-7940 SP - 339-46 ST - The effect of pentoxifylline on the lung during cardiopulmonary bypass T2 - Eur J Cardiothorac Surg TI - The effect of pentoxifylline on the lung during cardiopulmonary bypass VL - 10 ID - 22 ER - TY - JOUR AB - Although numerous different polymers are used as implants or otherwise studied for many other biotechnical applications, there is a lack of basic models that correlate polymer characteristics with foreign body reactions. This study aims at developing one such model by systematically studying surface molecular mobility of polymeric implants in soft tissues in vivo. Changing the length of the alkyl side chain of poly(alkyl methacrylates) (PAMAs), provides an interesting opportunity to study the surface molecular mobility with minimal changes of the hydrophobicity of the surface. Thus, in this study three different PAMAs, with increasingly surface mobility; poly (isobutyl methacrylate) (PIBMA), poly(butyl methacrylate) (PBMA), and poly(lauryl methacralate) (PLMA) along with pure titanium (Ti) substrates were implanted in the dorsum of Sprague-Dawley rats. Inflammatory cell recruitment, cell adhesion, and cytokine release were studied after 1, 3, and 28 days of implantation. Total number of inflammatory cells in the exudate was measured but no correlation between surface mobility and cell recruitment where found. However, the number of surface associated cells where significantly lower on the surfaces with high molecular mobility (PLMA and PBMA). The histological evaluation performed after 28 days revealed thicker fibrous capsule and a higher number of blood vessels on the low molecular mobility surface (PIBMA). After 28 days the cell activity was higher on the high molecular mobility surfaces (PLMA and PBMA) compared with PIBMA, based on the cytokine release. None of the surfaces induced any significant cell-death. On the basis of the results of this study we conclude that there is a significant difference in biological response to surfaces with different in molecular mobility. This might affect the wound healing process and the biocompatibility of biomaterials. © 2007 Wiley Periodicals, Inc. AD - Department of Cell and Molecular Biology, Interface Biophysics Lundberg Laboratory, Göteborg University, SE-405 30 Göteborg, Sweden Department of Biomaterials, Sahlgrenska Academy, Göteborg University, SE-405 30 Göteborg, Sweden Division of Oral and Maxillofacial Surgery, Maxillofacial Unit, Lanssjukhuset, Halmstad, Sweden AU - Andersson, M. AU - Suska, F. AU - Johansson, A. AU - Berglin, M. AU - Emanuelsson, L. AU - Elwing, H. AU - Thomsen, P. DB - Scopus DO - 10.1002/jbm.a.31389 IS - 3 KW - Fibrotic tissue Inflammatory system Polymers Surface molecular mobility Vascularisation M3 - Article N1 - Cited By :18 Export Date: 10 November 2020 PY - 2008 SP - 652-660 ST - Effect of molecular mobility of polymeric implants on soft tissue reactions: An in vivo study in rats T2 - Journal of Biomedical Materials Research - Part A TI - Effect of molecular mobility of polymeric implants on soft tissue reactions: An in vivo study in rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-39049162364&doi=10.1002%2fjbm.a.31389&partnerID=40&md5=316f832460135b30039bf65085b0ed9f VL - 84 ID - 1535 ER - TY - JOUR AB - PURPOSE: To evaluate changes in endothelial cell count after pterygium surgery with 5-minute application of mitomycin C (MMC) 0.02%. METHODS: The study participants included 24 consecutive patients (17 men and 7 women) who underwent pterygium surgery with MMC at a major tertiary center between September and October 2005. The bare sclera technique was used in all cases. After excision of the head and neck of the pterygium, a surgical sponge soaked with MMC 0.02% was placed on the exposed sclera for 5 minutes, with the conjunctival layer draped over the sponge. Thereafter, the sclera was irrigated with balanced salt solution, and surgery was completed. Endothelial images were acquired at the center of the cornea with a specular microscope (average of 3 measurements) before surgery and at 1 week, 1 month, and 3 months after surgery. RESULTS: Mean preoperative endothelial cell count was 2254 ± 128 cells/mm. The percentage of postoperative cell loss was 21.25% ± 2.8% at 1 week, 24.26% ± 1.8% at 1 month, and 21.05% ± 3.2% at 3 months. The difference in cell count from the preoperative value was significant at all time points (P < 0.02). There were no adverse drug effects and no serious operative complications. CONCLUSIONS: A 5-minute application of MMC 0.02% to the bare sclera during pterygium surgery has an immediate and significant effect on endothelial cell density, which remains stable for up to 90 days. Furthermore, longer-term studies are needed of different concentrations and durations of the drug and of procedures wherein MMC is applied before excision of the pterygium head. © 2008 by Lippincott Williams & Wilkins. AD - R. Avisar, Department of Ophthalmology and External Eye Disease, Rabin Medical Center, Hasharon Hospital, PO Box 121, Petah Tiqwa 49372, Israel AU - Avisar, R. AU - Avisar, I. AU - Bahar, I. AU - Weinberger, D. C1 - phenixin(Vitamed,Israel) C2 - Vitamed(Israel) DB - Embase Medline DO - 10.1097/ICO.0b013e318165b158 IS - 5 KW - balanced salt solution carbon tetrachloride chloramphenicol mitomycin polymyxin B prednisolone acetate absence of side effects article cell count cell density cell loss clinical article cornea endothelium drug effect endothelium cell excision eye pain female foreign body reaction human keratitis lacrimation lavage male outcome assessment photophobia priority journal pterygium sclera sex ratio specular microscopy surgical sponge tertiary health care treatment duration phenixin LA - English M3 - Article N1 - L354616800 2009-06-11 PY - 2008 SN - 0277-3740 SP - 559-561 ST - Effect of mitomycin C in pterygium surgery on corneal endothelium T2 - Cornea TI - Effect of mitomycin C in pterygium surgery on corneal endothelium UR - https://www.embase.com/search/results?subaction=viewrecord&id=L354616800&from=export http://dx.doi.org/10.1097/ICO.0b013e318165b158 VL - 27 ID - 597 ER - TY - JOUR AB - Capsular contracture is a potential adverse effect of breast implants. An inflammatory reaction is most likely the origin of fibrosis around the implant. It is possible that some substances may act to prevent this inflammatory reaction. Thus, our goal was to evaluate the effectiveness of local depot prednisolone phosphateliposomes (PPL) on fibrous capsule formation around textured silicone breast implants. Shell prostheses (2 mL) were implanted in the right (plus PPL group) and left (plus saline solution, saline group) subcutaneous dorsum of 18 rats. In another 18 rats, the implants were positioned in the left of the back without any drug instillation (control group). In the PPL group, the capsule thickness (mm) and density (%) of collagen were significantly (p < 0.0001) lower compared with the control group on days 35 and 90 postsurgery. Furthermore, in the PPL group, a significant reduction in myofibroblast count was observed on day 90 postsurgery (p < 0.0001). In conclusion, a single dose of depot liposome-delivered prednisolone was effective at impairing capsule formation around the silicone implant. The results suggest a strong local and weak systemic effect of PPL on the fibrous tissue around silicone implants. To our knowledge, no study has yet assessed the effect of PPL on silicone breast implants. © 2010 by the Wound Healing Society. AD - Plastic Surgery Brazilian Society (SBCP), Maringá, PR, Brazil Surgical Techniques and Experimental Surgery Division, Surgery Department, Federal University of São Paulo-UNIFESP-EPM, Rua Camé, 244, Mooca, São Paulo, SP CEP 03121020, Brazil Morphologic Department, Brazil Surgery Department, Federal University of São Paulo-UNIFESP-EPM, São Paulo, SP, Brazil Anesthesiology Department, State University of Londrina, Londrina, PR, Brazil Pharmacy, Pharmacology Department, State University ofMaringá (UEM), Maringá, PR, Brazil AU - Moreira, M. AU - Fagundes, D. J. AU - De Jesus Simoes, M. AU - Taha, M. O. AU - Perez, L. M. N. AU - Bazotte, R. B. DB - Scopus DO - 10.1111/j.1524-475X.2010.00601.x IS - 4 M3 - Article N1 - Cited By :23 Export Date: 10 November 2020 PY - 2010 SP - 417-425 ST - The effect of liposome-delivered prednisolone on collagen density, myofibroblasts, and fibrous capsule thickness around silicone breast implants in rats T2 - Wound Repair and Regeneration TI - The effect of liposome-delivered prednisolone on collagen density, myofibroblasts, and fibrous capsule thickness around silicone breast implants in rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77956856379&doi=10.1111%2fj.1524-475X.2010.00601.x&partnerID=40&md5=a78de1096c002561512b03bf2af9c3cb VL - 18 ID - 1455 ER - TY - JOUR AB - Objective: To asses the effect of insertion of mesh, with or without contact with the peritoneum, on the induction of bacterial translocation. Design: Open experimental study. Setting: Surgical research laboratory, Turkey. Subjects: 158 Swiss albino mice. Interventions: A defect in the abdominal wall was created. In the control group, the defect was closed primarily. In the extraperitoneal group, polypropylene mesh was sutured over the abdominal wall after primary closure of the peritoneum and in the intraperitoneal group, polypropylene mesh was sutured to close the created defect so that it was in contact with the intestines. Main outcome measures: Bacterial translocation at 4, 24 and 48 hours. Results: Insertion of mesh in contact with the peritoneum led to increased bacterial translocation to mesenteric lymph nodes at 4 (p=0.02) and 48 (p=0.03) hours compared with insertion without contact. Conclusion: Contact between a foreign body and the peritoneum is required to induce bacterial translocation. AD - Departments of General Surgery, Haccettepe Univ. Sch. of Med., Ankara, Turkey Departments of Microbiology, Haccettepe Univ. Sch. of Med., Ankara, Turkey 6th Department of Surgery, Ankara Numune Hospital, Ankara, Turkey Sedat Simavi Sokak, TR-06450 Ankara, Turkey AU - Baykal, A. AU - Günbatili, F. AU - Aran, Ö AU - Hasçelik, G. AU - Korkmaz, A. AU - Sayek, I. DB - Scopus DO - 10.1080/110241599750006938 IS - 4 KW - Bacterial translocation Mesh Polypropylene M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 1999 SP - 378-382 ST - Effect of intraperitoneal and extraperitoneal insertion of mesh on bacterial translocation: Does it make a difference? T2 - European Journal of Surgery TI - Effect of intraperitoneal and extraperitoneal insertion of mesh on bacterial translocation: Does it make a difference? UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032769165&doi=10.1080%2f110241599750006938&partnerID=40&md5=54214bc8bafaeba8596cc621f4963a91 VL - 165 ID - 1686 ER - TY - JOUR AB - Despite significant advances in the understanding of tissue responses to biomaterials, most implants are still plagued by inflammatory responses which can lead to fibrotic encapsulation. This is of dire consequence in tissue engineering, where seeded cells and bioactive components are separated from the native tissue, limiting the regenerative potential of the design. Additionally, these interactions prevent desired tissue integration and angiogenesis, preventing functionality of the design. Recent evidence supports that mesenchymal stem cells (MSC) and hematopoietic stem cells (HSC) can have beneficial effects which alter the inflammatory responses and improve healing. The purpose of this study was to examine whether stem cells could be targeted to the site of biomaterial implantation and whether increasing local stem cell responses could improve the tissue response to PLGA scaffold implants. Through incorporation of SDF-1α through factor adsorption and mini-osmotic pump delivery, the host-derived stem cell response can be improved resulting in 3X increase in stem cell populations at the interface for up to 2 weeks. These interactions were found to significantly alter the acute mast cell responses, reducing the number of mast cells and degranulated mast cells near the scaffold implants. This led to subsequent downstream reduction in the inflammatory cell responses, and through altered mast cell activation and stem cell participation, increased angiogenesis and decreased fibrotic responses to the scaffold implants. These results support that enhanced recruitment of autologous stem cells can improve the tissue responses to biomaterial implants through modifying/bypassing inflammatory cell responses and jumpstarting stem cell participation in healing at the implant interface. © 2010 Elsevier Ltd. AD - Bioengineering Department, University of Texas at Arlington, PO Box 19138, Arlington, TX 76019-0138, United States AU - Thevenot, P. T. AU - Nair, A. M. AU - Shen, J. AU - Lotfi, P. AU - Ko, C. Y. AU - Tang, L. DB - Scopus DO - 10.1016/j.biomaterials.2010.01.144 IS - 14 KW - Angiogenesis Biocompatibility Hematopoietic stem cells Inflammation Mesenchymal stem cell Scaffold M3 - Article N1 - Cited By :187 Export Date: 10 November 2020 PY - 2010 SP - 3997-4008 ST - The effect of incorporation of SDF-1α into PLGA scaffolds on stem cell recruitment and the inflammatory response T2 - Biomaterials TI - The effect of incorporation of SDF-1α into PLGA scaffolds on stem cell recruitment and the inflammatory response UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77649275535&doi=10.1016%2fj.biomaterials.2010.01.144&partnerID=40&md5=756f4ddecc9f09338a8316c623f55b24 VL - 31 ID - 1460 ER - TY - JOUR AB - Purpose: To evaluate the influence of heparin sodium in the irrigation solution on postoperative inflammation and cellular reaction on the anterior surface of a hydrophilic intraocular lens (IOL). Setting: Department of Ophthalmology, University of Vienna, Vienna, Austria. Methods: This randomized prospective single-surgeon study included 50 patients with senile cataract only. Half the patients received 1 mL of heparin sodium (concentration 10 IU/mL) in addition to the regular irrigating solution. In all other respects, the procedure was standardized: clear corneal incision, phacoemulsification, and implantation of a Hydroview® foldable hydrogel IOL (Bausch & Lomb). The parameters of inflammation-anterior chamber flare and cells-were evaluated with the pupil dilated in a masked fashion using a Kowa FC-1000 laser flare-cell meter 1, 3, 7, 14, and 28 days and 3, 6 and 12 months postoperatively. The cellular reaction was semiquantitatively examined and analyzed by specular microscopy. Results: In both groups, flare and cell values increased on the first postoperative day and successively decreased thereafter. In the first week, the flare and cell values were significantly higher in the group without heparin sodium in the irrigating solution. Subsequently, there were no differences between the 2 groups in flare or cells. At 1 day, the heparin sodium group had statistically significantly fewer IOLs with no cells on the surface. Subsequently, no differences in cellular reaction on the IOL were observed. Conclusions: Heparin sodium added to the standard irrigating solution reduced disturbances of the blood-aqueous barrier in the early postoperative period. There seemed to be no long-term effect, especially on cellular reaction, on the hydrophilic IOL surface. © 2002 ASCRS and ESCRS. AD - Department of Ophthalmology, University of Vienna, Allgemeines Krankenhaus, Waehringer Guertel 18-20, A-1090 Vienna, Austria Department of Ophthalmology, University of Vienna, Vienna, Austria AU - Kruger, A. AU - Amon, M. AU - Abela-Formanek, C. AU - Schild, G. AU - Kolodjaschna, J. AU - Schauersberger, J. DB - Scopus DO - 10.1016/S0886-3350(01)00861-6 IS - 1 M3 - Article N1 - Cited By :25 Export Date: 10 November 2020 PY - 2002 SP - 87-92 ST - Effect of heparin in the irrigation solution on postoperative inflammation and cellular reaction on the intraocular lens surface T2 - Journal of Cataract and Refractive Surgery TI - Effect of heparin in the irrigation solution on postoperative inflammation and cellular reaction on the intraocular lens surface UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036144224&doi=10.1016%2fS0886-3350%2801%2900861-6&partnerID=40&md5=806d486d3873af14a6473279b98e99ee VL - 28 ID - 1660 ER - TY - JOUR AB - BACKGROUND: During functionality testing and packaging of reusable surgical instruments (RSI) for sterilization, instruments are frequently touched. There is a lack of standards relating to hand hygiene frequency and use of gloves in the sterilizing service unit packing area. AIM: To determine the effect of hand hygiene and glove use on maintenance of RSI cleanliness. METHODS: Following manual and automated cleaning, Halsted-mosquito forceps were assessed for adenosine triphosphate (ATP), protein and microbial contamination after handling with gloved and ungloved but washed hands using an ATP surface swab test, bicinchoninic acid assay, and standard culture plate/broth, respectively. Gram's stain was used to classify the isolates. RSI contamination was assessed immediately following and 1, 2, and 4 h after washing hands. FINDINGS: Packing instruments with hands that had been unwashed for 2 or 4 h resulted in a significant increase in contaminating ATP when compared with all other treatment groups (P < 0.05). There was a significant correlation between the time since washing hands, the amount of ATP (r = 0.93; P ≤ 0.001), and the microbial load (r = 0.83; P ≤ 0.001) contaminating the forceps, where the longer the time the hands remained unwashed the higher the contamination. Significantly more contaminating protein was found on forceps handled with ungloved hands that had not been washed for 2 or 4 h (P < 0.001). CONCLUSION: Critical RSI inspection, assembling, lubricating and packing should be performed using either gloves or within 1 h of washing hands. AD - Surgical Infection Research Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia; Faculty of Nursing, Federal University of Goias, Goiania, Brazil. Faculty of Nursing, Federal University of Goias, Goiania, Brazil. Macquarie University Hospital, Macquarie University, Sydney, Australia. Surgical Infection Research Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia. Surgical Infection Research Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia. Electronic address: karen.vickery@mq.edu.au. AN - 28647423 AU - Costa, D. M. AU - Lopes, L. K. O. AU - Tipple, A. F. V. AU - Castillo, R. B. AU - Hu, H. AU - Deva, A. K. AU - Vickery, K. DA - Dec DO - 10.1016/j.jhin.2017.06.018 DP - NLM ET - 2017/06/26 IS - 4 KW - Adenosine Triphosphate/analysis Equipment Contamination/*prevention & control Gloves, Surgical/*statistics & numerical data Hand Hygiene/*methods Humans Infection Control/*methods Microbiological Techniques Proteins/analysis Surgical Instruments/*microbiology Colony count Gloves Hand hygiene Microbial Sterilization Surgical instruments LA - eng N1 - 1532-2939 Costa, D M Lopes, L K O Tipple, A F V Castillo, R B Hu, H Deva, A K Vickery, K Journal Article England J Hosp Infect. 2017 Dec;97(4):348-352. doi: 10.1016/j.jhin.2017.06.018. Epub 2017 Jun 21. PY - 2017 SN - 0195-6701 SP - 348-352 ST - Effect of hand hygiene and glove use on cleanliness of reusable surgical instruments T2 - J Hosp Infect TI - Effect of hand hygiene and glove use on cleanliness of reusable surgical instruments VL - 97 ID - 194 ER - TY - JOUR AB - Wound infection after prosthetic material implantation is a troublesome complication with an incidence of 2% to 10%. The effect of granulocyte colony-stimulating factor (G-CSF) was studied in an experimental methicillin-resistant Staphylococcus aureus (MRSA) graft infection model. Eighty adult mice were used. Under general anesthesia an abdominal incision of 2 cm in length was performed. A subcutaneous cavity of 2 × 2 cm in size was created. Polypropylene mesh pieces of 2 × 1 cm and MRSA solution of 0.1ml of 108 CFU/mL were used. G-CSF was applied systemically or locally in a dosage of 0.02 MU/30 g body weight. There were 8 groups: group I, wound + MRSA; group II, wound + mesh + MRSA; group III, wound + mesh + MRSA + G-CSF (ip, 48 h before operation); group IV, wound + mesh + MRSA + G-CSF (ip, 24 h before operation); group V, wound + mesh + MRSA + G-CSF (locally, into the cavity); group VI, wound + mesh (incubated in G-CSF solution for 4 h) + MRSA; group VII, wound + mesh + MRSA + G-CSF, ip, 24 h from operation; and group VIII (positive control group), wound + mesh + MRSA + Teicoplanin (0.03 mg/30 g body weight, ip, 1/2 h before operation). Three days after, animals were killed and incisions were examined for possible infection or abscess formation and wound failure. Meshes were removed; after vortexing and dilution, samples were incubated with 5% agar media. Results of bacterial incubation were evaluated 24 h and 48 h later. There were symptoms of wound infection and abscess formation in all groups except group VIII. In group VIII, MRSA was isolated in 7 events with a colony count below 103. Bacterial counts were above 106 (106-108) in all other groups. Thus, it was observed that wound infection could be created with this model, but G-CSF could not prevent the development of wound infection, whether it was administered systemically or locally. Teicoplanin decreased the number of colony-forming units of MRSA, and prevents wound infection in this MRSA wound infection model. Copyright © Taylor & Francis Inc. AD - Department of Infectious Diseases and Clinical Microbiology, Kirikkale University, School of Medicine, Kirikkale, Turkey Department of General Surgery, Suleyman Demirel University, School of Medicine, Isparta, Turkey Department of Pathology, Suleyman Demirel University, School of Medicine, Isparta, Turkey Department of General Surgery, Kirikkale University, School of Medicine, Kirikkale, Turkey Gumus Sokak D 13.4 Emlak Bankasi, Cayyolu 06120 Ankara, Turkey AU - Agalar, C. AU - Eroglu, E. AU - Sari, M. AU - Sari, A. AU - Daphan, C. AU - Agalar, F. DB - Scopus DO - 10.1080/08941930500248581 IS - 5 KW - Foreign-body infection G-CSF MRSA Teicoplanin M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2005 SP - 227-231 ST - The effect of G-CSF in an experimental MRSA graft infection in mice T2 - Journal of Investigative Surgery TI - The effect of G-CSF in an experimental MRSA graft infection in mice UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-32144438125&doi=10.1080%2f08941930500248581&partnerID=40&md5=9a9e7ab064e64f73ff9bf3a4bbe7a86a VL - 18 ID - 1601 ER - TY - JOUR AB - Introduction The human larynx is a very important organ for communication. Many conditions lead to scarring of the vocal folds, decreasing voice quality. Objective We aimed to determine whether fibroblast growth factors (FGFs) may influence tissue integration of grafted fascia into the vocal folds of an animal model. Methods This is an experimental animal study with 12 adult rabbits that were submitted to a grafting fragment obtained from superficial cervical fascia into the vocal fold lamina propria, bilaterally. The right vocal fold was injected with FGFs. The animals were sacrificed after 1 month or 12 months, depending on the group they were assigned to, and a histological analysis of their vocal folds was performed. We analyzed the histological changes (such as the presence of fibrosis and neovascularization) induced by the acute or chronic inflammatory reactions. Results The FGFs induced acute inflammatory changes in all animals after 1 month of the initial experiment. The presence of FGFs triggered more fibrosis than the expected due to the surgical procedure itself when compared with the control side of all animals after 12 months of the initial experiment. Conclusions Fibroblast growth factors alone do not represent a good therapeutic option in phonosurgery, since we observed higher levels of fibrosis in the vocal fold lamina propria. Further studies combining more substances may be necessary to elucidate the best option to be used in this kind of surgery. Copyright © 2019 by Thieme Revinter Publicações Ltda, Rio de Janeiro, Brazil. AD - Departamento de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Universidade Estadual de Campinas, Rua Tessália Vieira de Camargo, 126, Campinas, SP, 13083-887, Brazil Department of Pathology, Universidade Estadual de Campinas, Campinas, SP, Brazil AU - Carvalho, E. G. B. AU - Machado-Júnior, A. J. AU - Pauna, H. F. AU - Nicola, E. M. D. AU - Altemani, A. M. A. M. AU - Crespo, A. N. DB - Scopus DO - 10.1055/s-0038-1661399 IS - 1 KW - Fascia FGFs Fibroblasts Grafting Rabbits vocal folds M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 60-64 ST - The effect of fibroblast growth factors in grafted fascia into the vocal fold of rabbits T2 - International Archives of Otorhinolaryngology TI - The effect of fibroblast growth factors in grafted fascia into the vocal fold of rabbits UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049840731&doi=10.1055%2fs-0038-1661399&partnerID=40&md5=c70554a0f369cbbb1b48d06987eee479 VL - 23 ID - 1046 ER - TY - JOUR AB - Purpose. Secondary open-angle glaucoma may develop as a postoperative complication of early childhood cataract surgery. Its mechanism is poorly understood. Surgical removal of cataracts is typically incomplete, and we estimate that this disease is associated with alpha-B crystallin (CRYAB) secreted from the retained lens material. This study, for the first time, focused on the role of CRYAB in undesired changes of the structures and functions in trabecular meshwork (TM) cells. Methods. Cell proliferation and migration were assessed using a cell counting kit-8 (CCK8) and transwell assay analysis, respectively. Immunofluorescence (IF), quantitative real-time PCR (Rt-qPCR), and Western blot were performed to determine the effect of CRYAB on F-actin, tight junctions, and the expression of epithelial to mesenchymal transition- (EMT-) associated proteins in TM cells. Results. CRYAB promoted proliferation (p<0.0001), migration (p<0.001), and F-actin reorganization in TM cells. There were statistically significant increases in the mRNA and protein levels of zo-1, cadherin-N, and vimentin (all p<0.0001) and cadherin-E decreased (p<0.0001) and the mRNA level of claudin-1 increased (p<0.0001) compared to those of the control group. Conclusion. All of the changes in structures and functions first observed in the TM cells after exposure to CRYAB resembled alterations seen in primary open-angle glaucoma, suggesting that CRYAB might be related to the pathogenesis of secondary open-angle glaucoma after congenital cataract surgery. AD - Department of Ophthalmology, Peking University People’s Hospital, Eye diseases and Optometry Institute, Beijing Key Laboratory of Diagnosis and Therapy of Retina and Choroid Diseases, College of Optometry, Peking University Health Science Center, Beijing, China AN - 129104328. Language: English. Entry Date: 20180424. Revision Date: 20180424. Publication Type: Article AU - Xu, Hui AU - Zhu, Li AU - Wang, Yu AU - Bao, Yongzhen DB - ccm DO - 10.1155/2018/7875318 DP - EBSCOhost KW - Molecular Chaperones -- Adverse Effects Cataract Extraction -- Adverse Effects Anterior Eye Segment -- Pathology Glaucoma -- Etiology Postoperative Complications Retained Instruments Human Cell Proliferation Cell Migration Assays Fluorescent Antibody Technique Polymerase Chain Reaction -- Methods Blotting, Western Cell Count Cell Physiology Epithelial Cells Stem Cells RNA, Messenger Microfilament Proteins Cell Adhesion Molecules Cytoskeletal Proteins Membrane Proteins Gene Expression N1 - pictorial; research; tables/charts. Journal Subset: Biomedical; USA. NLM UID: 101524199. PY - 2018 SN - 2090-004X SP - 1-8 ST - Effect of Exogenous Alpha-B Crystallin on the Structures and Functions of Trabecular Meshwork Cells T2 - Journal of Ophthalmology TI - Effect of Exogenous Alpha-B Crystallin on the Structures and Functions of Trabecular Meshwork Cells UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=129104328&site=ehost-live&scope=site ID - 736 ER - TY - JOUR AB - The effect of dietary supplementation with 0, 100 and 450 mg of vitamin E (DL-α tocopheryl acetate)/kg of a dry diet on the kinetics of macrophage recruitment and giant cell formation in the pacu, maintained at different stocking densities (5 kg/m3 and 20 kg/m3), was investigated by insertion of round glass coverslips into the subcutaneous connective tissue. After a feeding period of 18 weeks, the coverslips were implanted and later removed for examination at 2, 7 and 15 days post-implantation. Fish fed diets supplemented with 450 mg of vitamin E showed an increase (P<0.05) in the accumulation of macrophages, foreign body giant cells and Langhans type cells. The kinetics of macrophage recruitment and giant cell formation on the glass coverslips appeared to be strongly influenced by vitamin E supplementation, since fish fed a basal diet and held at high stocking densities showed low numbers of adhering cells on the coverslips, and high concentrations of plasma corticosteroids. On the other hand, fish given a diet supplemented with 450 mg of vitamin E did not show a similar difference in plasma cortisol concentrations related to stocking density. The effect of cortisol concentrations on carbohydrate metabolism, analysed by assessment of plasma glycaemia, was not clear. Blood glucose concentrations did not vary substantially with the different treatments examined. These results suggest that vitamin E may contribute to the efficiency of the fish's inflammatory response by increasing macrophage recruitment and giant cell formation in the foreign body granulomatous reaction. Vitamin E appeared to act on the stress response of pacus by preventing a stress-related immunosuppression. © 2005 Elsevier Ltd. All rights reserved. AD - Department of Veterinary Pathology, São Paulo State University Unesp, Jaboticabal, Brazil Aquaculture Centre, São Paulo State University Unesp, Jaboticabal, Brazil Department of Technology, São Paulo State University Unesp, Jaboticabal, Brazil AU - Belo, M. A. A. AU - Schalch, S. H. C. AU - Moraes, F. R. AU - Soares, V. E. AU - Otoboni, A. M. M. B. AU - Moraes, J. E. R. DB - Scopus DO - 10.1016/j.jcpa.2005.04.004 IS - 2-3 KW - Alpha-tocopherol Cortisol Fish Piaractus mesopotamicus Polykaryon macrophage Vitamin E M3 - Article N1 - Cited By :70 Export Date: 10 November 2020 PY - 2005 SP - 146-154 ST - Effect of dietary supplementation with vitamin E and stocking density on macrophage recruitment and giant cell formation in the teleost fish, Piaractus mesopotamicus T2 - Journal of Comparative Pathology TI - Effect of dietary supplementation with vitamin E and stocking density on macrophage recruitment and giant cell formation in the teleost fish, Piaractus mesopotamicus UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-23844436459&doi=10.1016%2fj.jcpa.2005.04.004&partnerID=40&md5=cceda16c3a0965ca01684f6d838b5f41 VL - 133 ID - 1602 ER - TY - JOUR AB - PURPOSE: Hyaluronan mediates growth of SW620 colon cancer cells. Because hyaluronan is the active ingredient in Seprafilm®, we hypothesized that Seprafilm® would affect intraperitoneal tumor growth in a mouse model of peritoneal seeding. METHODS: Immunodeficient mice underwent laparotomy and intraperitoneal inoculation of 105 SW620 cells. Seprafilm® (n = 22), Vicryl mesh (foreign body control; n = 24), or no material (sham; n = 19) was placed under the incision. Mice were killed after four weeks and tumors were dissected, counted, and weighed. RESULTS: Ninety-five percent of mice in the sham group and 96 percent in the Vicryl group developed intraperitoneal tumors. In contrast, only 64 percent of mice in the Seprafilm® group developed tumors (P = 0.024), and these tumors were smaller than those in the sham group; (Seprafilm® = 42 ± 9 mg vs. sham = 82 ± 17 mg; P = 0.05). In contrast, tumors in the Vicryl group were dramatically larger (349 ± 49 mg; P < 0.001 vs. sham or Seprafilm®). CONCLUSIONS: Despite previous data that suggested that hyaluronan increases colon cancer cell growth, we found that Seprafilm® decreased tumor formation and tended to decrease size in this model. In contrast, Vicryl mesh increased tumor formation and size. Our results suggest that Seprafilm® does not promote intraperitoneal tumor growth, especially compared with Vicryl mesh. © 2008 The American Society of Colon and Rectal Surgeons. AD - Department of Surgery, University of Minnesota, Minneapolis, MN, United States Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, United States Department of Surgery and Surgical Oncology, Roswell Park Cancer Institute, University at Buffalo/State University of New York, Buffalo, NY, United States Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, United States AU - Lee, P. K. AU - Windsperger, A. P. AU - Wilson, C. M. AU - McCarthy, J. B. AU - Wasiluk, K. R. AU - Rothenberger, D. A. AU - Bullard Dunn, K. M. DB - Scopus DO - 10.1007/s10350-008-9299-z IS - 9 KW - Colon cancer Hyaluronan Polyglactin Seprafilm® Vicryl M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2008 SP - 1403-1407 ST - The effect of a hyaluronan-carboxymethylcellulose membrane vs. polyglactin 910 mesh on intra-abdominal tumor formation in mice T2 - Diseases of the Colon and Rectum TI - The effect of a hyaluronan-carboxymethylcellulose membrane vs. polyglactin 910 mesh on intra-abdominal tumor formation in mice UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-49749118658&doi=10.1007%2fs10350-008-9299-z&partnerID=40&md5=a88fb1082282783f25b238220fb32d42 VL - 51 ID - 1517 ER - TY - JOUR AD - Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, United States University of Michigan, Ann Arbor, Michigan, United States AU - Bole, G. G., Jr. AU - Heath, L. E. DB - Scopus DO - 10.1002/art.1780100408 IS - 4 M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 1967 SP - 377-387 ST - The effect of 6‐mercaptopurine on the inflammatory response stimulated by subcutaneous implantation of polyvinyl sponge T2 - Arthritis & Rheumatism TI - The effect of 6‐mercaptopurine on the inflammatory response stimulated by subcutaneous implantation of polyvinyl sponge UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014119105&doi=10.1002%2fart.1780100408&partnerID=40&md5=f568fa11bbaea5d810789afb82f8da56 VL - 10 ID - 1789 ER - TY - JOUR AN - 4423102 AU - Russell, J. B. DA - Dec DP - NLM ET - 1974/12/01 IS - 6 KW - Foreign Bodies/*prevention & control Humans *Malpractice Postoperative Complications/prevention & control *Surgical Instruments *Surgical Procedures, Operative LA - eng N1 - Russell, J B Journal Article United States Surg Gynecol Obstet. 1974 Dec;139(6):919. PY - 1974 SN - 0039-6087 (Print) 0039-6087 SP - 919 ST - Editorial: Medicolegal necessity for counting sharps T2 - Surg Gynecol Obstet TI - Editorial: Medicolegal necessity for counting sharps VL - 139 ID - 2 ER - TY - JOUR AB - The author recounts his early experience with implants for the posterior chamber made of silicone. While the numbers are small the visual results appear to be satisfactory. The results, however, are marred by an as yet unacceptable rate of post‐operative complications. Copyright © 1988, Wiley Blackwell. All rights reserved AD - Moorfields Bye Hospital, London, United Kingdom AU - Steele, A. O. McG DB - Scopus DO - 10.1111/j.1442-9071.1988.tb01258.x IS - 2 KW - hydrogel lens Polymethylmethacrilate silicone intraocular implant. M3 - Article N1 - Export Date: 10 November 2020 PY - 1988 SP - 107-109 ST - EARLY EXPERIENCES WITH SOFT INTRAOCULAR IMPLANTS T2 - Australian and New Zealand Journal of Ophthalmology TI - EARLY EXPERIENCES WITH SOFT INTRAOCULAR IMPLANTS UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023732366&doi=10.1111%2fj.1442-9071.1988.tb01258.x&partnerID=40&md5=8f4147092888db134b6c5eb86a9b6abc VL - 16 ID - 1743 ER - TY - JOUR AB - Ingestion of foreign bodies including dentures can be a cause of morbidity and mortality. We report a case of poor-fit denture in an elderly male with pulmonary and musculoskeletal comorbidities, who presented as an acute abdomen. The pin attached to the denture caused perforation of first part of duodenum. The only positive finding prior to surgery was a radiopaque density in the abdominal radiograph of the patient and air under the diaphragm. It is important for all the surgeons dealing with acute care patients to be aware of different designs and constructions of dentures. AD - Department of South Surgery Ward, Mayo Hospital, Lahore, Pakistan Department of General Surgery, King Edward Medical University, Lahore, Pakistan AU - Siddiq, M. AU - Qureshi, A. U. AU - Farooq, M. S. AU - Ali, A. A. DB - Scopus IS - 12 KW - Denture design Geriatric pop Ingested foreign bodies Partial denture M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2017 SP - 778-779 ST - Duodenal perforation due to ingested partial denture T2 - Journal of the College of Physicians and Surgeons Pakistan TI - Duodenal perforation due to ingested partial denture UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85035793511&partnerID=40&md5=e73085e9741ca8ff1e6f0ab6b59530dd VL - 27 ID - 1108 ER - TY - JOUR AB - LEARNING OBJECTIVE 1: Diagnose bacterial endocarditis in the absence of echocardiographic evidence of endocardial involvement. CASE: A42-year-old man presented with a two-day history of right hand pain and swelling, which began the day prior while injecting heroin into his hand. He had been awoken from sleep that morning by a sharp, left-sided chest pain that worsened with deep inspiration and was associated with shortness of breath. Temperature was 104.4 °F, heart rate was 122 beats per minute, blood pressure was 169/109, respirations were 22 breaths per minute, and oxygen saturation was 84 % on room air. Past medical history was significant for opiate abuse, hypertension, Type 2 diabetes, and previous trauma to the right hand with residual orthopedic hardware. The patient's hand was warm, swollen, and tender to palpation along the dorsum. Peripheral white blood cell count was significantly elevated and a plain radiograph of the hand showed soft tissue swelling with foreign bodies and no evidence of osteomyelitis. A chest x-ray was normal; CT PE protocol revealed multiple nodules in each lung, concerning for cavitation. A transthoracic echocardiogram was negative, but given the high suspicion for endocarditis, a transesophageal echocardiogram was performed, and was also negative. All three sets of blood cultures, drawn on admission, quickly resulted as grampositive cocci in clusters, ultimately identified as Methicillin-Resistant Staphylococcus aureus. Despite the lack of visual evidence of endocardial involvement, the patient was diagnosed with acute bacterial endocarditis based on the Modified Duke Criteria. DISCUSSION: Bacterial endocarditis is a life-threatening condition frequently treated by general internists. The estimated annual incidence is between three to nine cases per 100,000 people, with twice as many men as women effected. Patients classified as 'highrisk' include intravenous drug users and individuals with prosthetic valves or a prior history of valvular disease, and have a much higher infection rate. The diagnosis of bacterial endocarditis is made based on the Modified Duke Criteria, which have a greater than 80 % sensitivity, specificity, and negative predictive value. In 90 % of cases, vegetations are seen on transthoracic or transesophageal echocardiogram, which is one of the two major Duke Criteria. The other major criterion is bacteremia by an organism commonly known to cause endocarditis; if both major criteria are met the diagnosis of definitive bacterial endocarditis is made. In the other 10%of cases, diagnosis must include at least three minor criteria, such as a predisposing condition, fever, vascular or immune phenomena, or positive blood cultures with an organism not commonly known to cause endocarditis. Definitive endocarditis can be diagnosed in a patient with one major and three minor criteria, or with no major but all five minor criteria. In this case, the patient met one major and three minor criteria: Staphylococcus aureus bacteremia, a predisposing condition (intravenous drug use), fever, and a vascular phenomenon (septic pulmonary emboli as seen on chest CT). With intravenous drug use on the rise, general internists should be familiar with the Modified Duke Criteria for diagnosing endocarditis, particularly when echocardiography does not correlate with clinical presentation. AD - F. Kaiksow, Tulane University Health Sciences Center, New Orleans, LA, United States AU - Kaiksow, F. AU - Putnam, P. J. DB - Embase KW - diamorphine opiate society internal medicine diagnosis human bacterial endocarditis endocarditis patient echocardiography blood culture organisms male endocardium fever internist soft contact lens drug use thorax blood pressure foreign body hand pain soft tissue heart rate palpation temperature female computer dyspnea X ray film injury non insulin dependent diabetes mellitus staphylococcal bacteremia lung embolism leukocyte count swelling edema infection rate osteomyelitis thorax pain hypertension heart valve prosthesis abuse sleep intravenous drug abuse methicillin resistant Staphylococcus aureus medical history ambient air predictive value vegetation bacteremia oxygen saturation lung breathing thorax radiography LA - English M3 - Conference Abstract N1 - L71495526 2014-06-17 PY - 2014 SN - 0884-8734 SP - S349 ST - Duke it out: Finding the right diagnosis T2 - Journal of General Internal Medicine TI - Duke it out: Finding the right diagnosis UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71495526&from=export VL - 29 ID - 451 ER - TY - JOUR AB - Background and study aims: Major leakage from an esophageal anastomosis is a life-threatening surgical complication. Endoscopically guided endoluminal vacuum therapy using polyurethane sponges is a new method for treating such leakage. Patients and methods: Between June 2007 and June 2009, five patients (mean age 68 years) who developed anastomotic leakage after esophageal surgery were prospectively evaluated. After endoscopic diagnosis of a major leakage, polyurethane sponges were endoscopically positioned in the wound cavity of the anastomosis. Continuous suction was applied via drainage tubes fixed to the sponges. Initially sponges were endoscopically changed three times per week. Results: In all five patients treatment was successful. Median time to reduce levels of inflammation markers by 50% was 10 days for white blood cell (WBC) count and 7 days for C-reactive protein (CRP). The smallest initial wound cavity size was 42cm3 and the largest was 157cm3. The median duration of drainage was 28 days, with a median of 9 sponge changes and a median time to total cavity closure of 42 days. Two patients needed anastomotic dilation by Savary-Miller bougienage due to stenosis found on further follow-up. One of these patients died of acute severe hemorrhage from an aortoanastomotic fistula after the dilation procedure. Conclusions: Endoscopically assisted vacuum therapy is a well-tolerated and effective therapeutic option for treatment of major esophageal leaks after surgery. Additional surgery was avoided in all cases. However, the occurrence of a delayed aortoesophageal fistula calls for careful further investigation of this new technique. © Georg Thieme Verlag KG Stuttgart. AD - B. Schniewind, University Hospital of Schleswig-Holstein, Campus Kiel Clinic for General and Thoracic Surgery, Arnold-Heller-Strasse 3 (Haus 18), D-24105 Kiel, Germany AU - Ahrens, M. AU - Schulte, T. AU - Egberts, J. AU - Schafmayer, C. AU - Hampe, J. AU - Fritscher-Ravens, A. AU - Broering, D. C. AU - Schniewind, B. DB - Embase Medline DO - 10.1055/s-0030-1255688 IS - 9 KW - C reactive protein inotropic agent polyurethan adult aged anastomosis leakage aortoesophageal fistula article cardiovascular disease clinical article clinical evaluation clinical trial disease marker disease severity endoscopic therapy endoscopic vacuum therapy endoscopy esophageal leakage esophagus anastomosis esophagus dilatation esophagus disease esophagus stenosis esophagus surgery female hemorrhagic shock human inflammation leukocyte count male pilot study postoperative hemorrhage priority journal prospective study suction drainage surgical sponge surgical technique treatment outcome upper gastrointestinal bleeding vacuum assisted closure wound drainage LA - English M3 - Article N1 - L359477380 2010-09-14 2010-09-16 PY - 2010 SN - 0013-726X 1438-8812 SP - 693-698 ST - Drainage of esophageal leakage using endoscopic vacuum therapy: A prospective pilot study T2 - Endoscopy TI - Drainage of esophageal leakage using endoscopic vacuum therapy: A prospective pilot study UR - https://www.embase.com/search/results?subaction=viewrecord&id=L359477380&from=export http://dx.doi.org/10.1055/s-0030-1255688 VL - 42 ID - 556 ER - TY - JOUR AN - 105559505. Language: English. Entry Date: 20090102. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 4 KW - Cesarean Section Nursing Care -- Standards Retained Instruments Witness, Legal Communication -- Methods Nurse-Physician Relations Nursing Role Surgical Count Procedure N1 - legal case. Journal Subset: Blind Peer Reviewed; Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Legal Case: Petryshyn v. Slotky, IL. NLM UID: 100936959. PMID: NLM18844131. PY - 2008 SN - 1528-848X SP - 1-1 ST - Dr. allowed to testify as expert on nursing: was this error? T2 - Nursing Law's Regan Report TI - Dr. allowed to testify as expert on nursing: was this error? UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105559505&site=ehost-live&scope=site VL - 49 ID - 944 ER - TY - JOUR AB - Hardware removal after complete fracture healing is a laborious and traumatic procedure that bears the risks of refracture, infection, and soft tissue damage. Absorbable materials for fracture fixation have the advantage of eliminating the need for removal, however, they may stimulate a considerable inflammatory response. For that reason, we compared in a prospective randomized experimental animal model study the incidence of foreign-body reactions between Inion OTPSTM absorbable plate implants, consisting of carbon trimethylene, L-polylactic acid, and D, L-polylactic acid, and conventional titanium plates. Seventy rabbits were equally divided into two groups. Titanium (Group A) or absorbable (Group B) plates and screws were implanted in the femoral shaft of the rabbits. Wound reaction and laboratory tests including White Blood Cells count (WBC), Erythrocyte Sedimentation Rate (ESR), and C-reactive Protein (CRP) values were measured and compared at different time points. Radiographs and histological analysis of tissue samples from all animals were also used to identify potential foreign-body reactions. WBC showed normal values in both Groups. In Group A, ESR levels were higher at all time points but CRP values were normalized at 3 weeks postoperatively. In Group B, ESR and CRP levels reached a peak at 3 weeks and were above normal values throughout the whole experiment (p<0.001). Radiologic examination revealed periosteal thickening and surrounding sclerosis in 23 out of 35 animals of Group B (66%). All Group A animals had normal radiographic findings. Histopathology showed a typical non-specific foreign-body reaction in all animals in Group B (100%) but none in Group A. However, only four of them (11.8%) developed non-infected wound complications and showed significantly elevated CRP and ESR values (p=0.054). Although Inion OTPSTM Biodegradable Plating System stimulate a foreign-body reaction, only a small but not negligible percentage of almost 12% may lead to wound problems. However, this difference compared to titanium plates was of borderline not statistically significant. Future studies should focus on the development of absorbable implants with improved biocompatibility aiming to further decrease the potential of foreign-body reaction and eliminate the need for additional reoperative procedures. AD - 1st Orthopaedic Department, Aristoteleio Panepistemio Thessalonikes Schole Epistemon Ygeias, Thessaloniki, Thessaloniki, 57010, GREECE. 1st Orthopaedic Department, Aristoteleio Panepistemio Thessalonikes Schole Epistemon Ygeias, Thessaloniki, Thessaloniki, GREECE. AN - 32629429 AU - Chalidis, B. AU - Kitridis, D. AU - Savvidis, P. AU - Papalois, A. AU - Givissis, P. DA - Jul 6 DO - 10.1088/1748-605X/aba326 DP - NLM ET - 2020/07/07 KW - absorbable implants foreign-body reaction rabbits LA - eng N1 - 1748-605x Chalidis, Byron Orcid: 0000-0003-1305-2734 Kitridis, Dimitrios Savvidis, Panagiotis Papalois, Apostolos Givissis, Panagiotis Journal Article England Biomed Mater. 2020 Jul 6. doi: 10.1088/1748-605X/aba326. PY - 2020 SN - 1748-6041 ST - Does the Inion OTPS(TM)absorbable plating system induce higher foreign-body reaction than titanium implants? An experimental randomized comparative study in rabbits T2 - Biomed Mater TI - Does the Inion OTPS(TM)absorbable plating system induce higher foreign-body reaction than titanium implants? An experimental randomized comparative study in rabbits ID - 255 ER - TY - JOUR AD - Perioperative Unit Clinical Nurse Educator, Hawkes Bay District Health Board (HBDHB) AN - 106290636. Language: English. Entry Date: 20070525. Revision Date: 20150818. Publication Type: Journal Article. Journal Subset: Australia & New Zealand AU - Koorey, J. DB - ccm DP - EBSCOhost IS - 4 KW - Documentation Surgical Count Procedure Hospital Policies Legislation, Nursing -- New Zealand Liability, Legal New Zealand New Zealand Nurses Organization -- Standards Perioperative Nursing Surgical Count Procedure -- History Surgical Instruments Surgical Patients Surgical Sponges N1 - Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. PY - 2007 SN - 1174-7579 SP - 23-30 ST - Documentation of the surgical count T2 - Dissector TI - Documentation of the surgical count UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106290636&site=ehost-live&scope=site VL - 34 ID - 858 ER - TY - JOUR AN - 3641326 AU - Tammelleo, A. D. DA - Oct DP - NLM ET - 1986/10/01 IS - 5 KW - Cesarean Section Female *Foreign Bodies *General Surgery Humans Infant, Newborn Male Malpractice/*legislation & jurisprudence Operating Room Nursing/*legislation & jurisprudence Pregnancy *Surgical Instruments Tennessee LA - eng N1 - Tammelleo, A D Case Reports Journal Article United States Regan Rep Nurs Law. 1986 Oct;27(5):1. PY - 1986 SN - 0034-3196 (Print) 0034-3196 SP - 1 ST - Doctors, nurses and "sponge counts" T2 - Regan Rep Nurs Law TI - Doctors, nurses and "sponge counts" VL - 27 ID - 13 ER - TY - JOUR AB - Blood contact with surfaces of the extracorporeal circuit provokes the activation of the coagulation system. To improve biocompatibility of the extracorporeal circuit without increasing the risk of bleeding, coatings of artificial surfaces were designed; many of them involve the use of heparin. Data in the literature show that heparin-induced thrombocytopenia is a major issue in the extracorporeal membrane oxygenation scenario, and no relevant benefits have been shown comparing heparin and no-heparin coating. © 2014 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc. AD - Department of Anesthesia and Intensive Care, San Raffaele Scientific Institute, Milan, Italy Institute of Anaesthesiology, Heart and Diabetes Centre North Rhine-Westphalia, Ruhr-University Bochum, Bad Oeynhausen, Germany AU - Silvetti, S. AU - Koster, A. AU - Pappalardo, F. DB - Scopus DO - 10.1111/aor.12335 IS - 2 KW - Blood coagulation-Extracorporeal membrane Oxygenation-Heparin-Circuit coating M3 - Article N1 - Cited By :24 Export Date: 10 November 2020 PY - 2015 SP - 176-179 ST - Do We Need Heparin Coating for Extracorporeal Membrane Oxygenation? New Concepts and Controversial Positions About Coating Surfaces of Extracorporeal Circuits T2 - Artificial Organs TI - Do We Need Heparin Coating for Extracorporeal Membrane Oxygenation? New Concepts and Controversial Positions About Coating Surfaces of Extracorporeal Circuits UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84922700340&doi=10.1111%2faor.12335&partnerID=40&md5=ca9b223b3dfcc285826f37a5572d89ee VL - 39 ID - 1244 ER - TY - JOUR AB - Do asymptomatic foreign bodies in the maxillary sinus always need to be removed? Foreign bodies may be displaced into the maxillary sinus as a result of trauma or during dental interventions. They commonly cause chrome sinusitis and/or fungal infections. This paper presents the case of a foreign body lodged in the right maxillary sinus ostium of a 31-year-old female patient. The foreign body was observed incidentally during radiological examination. After careful clinical and radiological examination, it was concluded that the foreign body was a piece of amalgam displaced into the maxillary sinus during a traumatic extraction. It is an uncommon finding to observe an asymptomatic dental foreign body in a position so close to the natural ostium of the maxillary sinus for so many years without any oro-antral fistula formation and/or sinusitis attacks. We describe the non-surgical approach to the case and the need for surgical management will be questioned. The importance of consultation between otolaryngologists and oral and maxillofacial surgeons will also be emphasised. AD - Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Istanbul University, Istanbul, Turkey Maresal Cakmak Military Hospital, Department of Otolaryngology and Head and Neck Surgery, Erzurum, Turkey AU - Selvi, F. AU - Enoz, M. AU - Yazgin, I. AU - Cakarer, S. AU - Keskin, C. DB - Scopus IS - 4 KW - Amalgam Chronic iatrogenic sinusitis Computed tomography Foreign body Maxillary sinus M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2008 SP - 243-247 ST - Do asymptomatic foreign bodies in the maxillary sinus always need to be removed? T2 - B-ENT TI - Do asymptomatic foreign bodies in the maxillary sinus always need to be removed? UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-58249117793&partnerID=40&md5=f828e8db66c00bd98d30bcbd3452e8ab VL - 4 ID - 1511 ER - TY - JOUR AB - Purpose: Chronic inflammation after injury and surgical intervention drives catabolic metabolism and many downstream events that lead to osteoarthritis. Pain, altered gait or muscle recruitment tissue destruction is some of the consequences that occur in both animals and human patients. Oral Non-steroidal anti-inflammatory drugs (NSAIDs) are associated with cardiovascular, hepatic, renal and gastrointestinal complications. NSAIDs also alter hemostasis, so they are often avoided when anti-coagulant therapy is used. Intra-articular injection of joints with drugs and proteins utilizing a sustained release carrier is a relatively novel method of delivering active pharmacological ingredients to the synovial environment. This method could be cost effective and safer than daily oral NSAIDs. The purpose of the current experiments was to gain a better understanding of the fate of a polymer carrier after intra-articular injection and potential mechanisms by which it delivers active ingredients to the synovial environment. Methods: Eighteen female adult sheep were assigned to 6 groups of n = 3 and their right stifle joint was injected with 0.6 mL of a biodegradable mix of two polymers comprising D,L-lactide and polyethylene glycol (PDL-PEG) proprietary polymer (BEPO™) combined with 102 mg of celecoxib and a biocompatible green dye (D&C #6). The contralateral limb was injected with 0.6 mL of physiologic saline USP. Plasma and synovial fluid were collected at times 0,1, 7,14 28, 42 and 90 days post injection. The sheep were sacrificed in groups of three at 0, 1, 7, 14 28, 42 and 90 days to collect articular cartilage, synovial membrane, menisci and any residual polymer in the synovial cavity. Macroscopic and histological observations (OARSI scoring) were conducted to characterize the polymer formulation and its interaction with synovial tissues. Plasma, synovial fluid and synovial tissue were analyzed for celecoxib concentration using HPLC. Automated counting to determine the synovial fluid leukocyte and protein concentration was measured using the total solids method. Results: Sheep that received polymer injections into the stifle joint experienced mild effusion for 3 days without lameness throughout the study. There was mild elevation in SF leukocyte concentrations (11.0 and 4.1 109/L) on days 1 and 7 respectively but protein concentration did not normalize until day 28. Very low (<10 ng/mL) levels of celecoxib were detectable in plasma on Day 1 only. Higher levels of celecoxib above the estimated therapeutic level were detected in the synovial fluid on Day 1 and declined to zero over 28 days, but celecoxib was detectable in synovial tissue until the end of the study at 90 days. Macroscopically, small polymer particles were found in all compartments, cul de sacs and gutters of the stifle joint demonstrating that the original polymer depot had been morselized and widely distributed. Most particles were adherent to the synovial membrane by day 7 and increasingly incorporated into the synovial tissues over time. Histology of the synovial membrane demonstrated that larger polymer particles were engulfed within folds of the synovial lining and hypertrophied synovial lining cells appeared to phagocytose smaller particles (Fig 1- left panel). Interestingly, where polymer was found within the synovial membrane a typical foreign body reaction was observed dominated by macrophages and giant cells resulting in degradation of the polymer particles (Fig. 1 right panel). The reactions were focal and localized to polymer; areas of synovial membrane lacking polymer displayed normal morphology. By day 28 there were minimal reactions to polymer particles and by day 90, no polymer was detected. There were no adverse effects on other synovial tissues. Conclusions: This study shows that the primary target of this sustained release drug formulation is likely to be the synovial membrane where the polymer matrix undergoes cellular degradation and hydrolysis whilst releasing the active ingredient. Celecoxib exposure in the circulation was minimal e iminating the potential for systemic complications, but celecoxib persisted in the synovial membrane longer than in synovial fluid. This mechanism of uptake and degradation suggests that the synovial membrane can be a depot for release of active pharmacological ingredients into the synovial environment. (Figure Presented). AD - M. Hurtig, Univ. of Guelph, Guelph, ON, Canada AU - Hurtig, M. AU - Shive, M. AU - Kapoor, M. AU - Mahomed, N. AU - Marshall, W. DB - Embase KW - polymer celecoxib protein anticoagulant agent nonsteroid antiinflammatory agent hexamethonium bromide sodium chloride dye macrogol sustained drug release intraarticular drug administration osteoarthritis society synovium synovial fluid plasma human environment sheep leukocyte injection adult pain knee meniscus therapy surgery articular cartilage hemostasis injury limb patient female tissues neurophysiological recruitment hydrolysis adverse drug reaction gait macrophage solid effusion foreign body reaction histology giant cell morphology drug formulation metabolism exposure chronic inflammation high performance liquid chromatography LA - English M3 - Conference Abstract N1 - L72246892 2016-04-21 PY - 2016 SN - 1063-4584 SP - S524-S525 ST - Disposition and ultimate fate of a PLA-peg sustained release polymer after intra-articular injection T2 - Osteoarthritis and Cartilage TI - Disposition and ultimate fate of a PLA-peg sustained release polymer after intra-articular injection UR - https://www.embase.com/search/results?subaction=viewrecord&id=L72246892&from=export VL - 24 ID - 408 ER - TY - JOUR AB - A critically ill patient had a major mitral paravalvular leak, failed device closure of the leak, and severe hemolytic anemia after a third mitral valve replacement. Echocardiography showed the Amplatzer occluder device completely displaced and swirled in the left atrial cavity. His condition was greatly improved after a fourth mitral valve replacement. © 2008 Published by European Association for Cardio-Thoracic Surgery. All rights reserved. AD - Department of Cardiac and Thoracic Surgery, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel AU - Yuan, S. M. AU - Shinfeld, A. AU - Raanani, E. DB - Scopus DO - 10.1510/icvts.2008.186627 IS - 6 KW - Amplatzer occluder device Complication Hemolytic anemia Mitral valve replacement Paravalvular leak M3 - Article N1 - Cited By :16 Export Date: 10 November 2020 PY - 2008 SP - 1131-1133 ST - Displacement of the Amplatzer occluder device from the mitral paraprosthetic leak T2 - Interactive Cardiovascular and Thoracic Surgery TI - Displacement of the Amplatzer occluder device from the mitral paraprosthetic leak UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-57349124813&doi=10.1510%2ficvts.2008.186627&partnerID=40&md5=a32ab887b3a17950336f136896212a9e VL - 7 ID - 1512 ER - TY - JOUR AB - INTRODUCTION: Dislodgement of orthodontic appliance into operation wounds may occur while performing orthognathic surgery. Its occurrence is commonly associated with bonded upper molar tube. CASE REPORT: A 25-year-old gentleman presented with recurrent upper right vestibular abscess three months following a bimaxillary orthognathic surgery. A bonded molar orthodontic tube had dislodged into the wound during the operation. The clinical presentation initially mimics an odontogenic infection until our investigations revealed that it originated from the dislodged appliance. The abscess was drained, the wound site was explored, and the molar tube and neighbouring rigid fixation plates and screws were removed. The patient recovered well following the procedure. CONCLUSION: Dislodged metal orthodontic appliance in oral wound acts as a foreign body that may exert allergic reactions, infection, or inflammation. Pre- and postoperative intraoral examination of fixed orthodontic appliances including its count should be recorded in orthognathic surgery protocol. AD - Oral and Maxillofacial Surgery Unit, School of Dental Sciences, University of Science Malaysia (USM), 16150 Kubang Kerian, Kelantan, Malaysia. Sharjah Institute for Medical Research (SIMR), University of Sharjah, Sharjah, UAE. AN - 29971169 AU - Shaeran, T. A. T. AU - Samsudin, A. R. C2 - PMC6009024 DO - 10.1155/2018/6540945 DP - NLM ET - 2018/07/05 LA - eng N1 - 2090-6455 Shaeran, Tengku Aszraf Tengku Samsudin, A R Orcid: 0000-0003-0373-837x Case Reports Case Rep Dent. 2018 Jun 4;2018:6540945. doi: 10.1155/2018/6540945. eCollection 2018. PY - 2018 SN - 2090-6447 (Print) SP - 6540945 ST - Dislodged Bonded Molar Tube into Wound during Orthognathic Surgery T2 - Case Rep Dent TI - Dislodged Bonded Molar Tube into Wound during Orthognathic Surgery VL - 2018 ID - 217 ER - TY - JOUR AN - 108090999. Language: English. Entry Date: 20081121. Revision Date: 20150712. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 4 KW - Human Nursing Practice, Evidence-Based Perioperative Nursing Surgical Count Procedure -- Evaluation N1 - abstract; commentary; research. Original Study: Greenberg CC, Regenbogen SE, Lipsitz SR, Diaz- Flores R, Gawande AA. The frequency and significance of discrepancies in surgical count. Ann Surg 2008; 248(2): 337-41. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2008 SN - 0001-2092 SP - 643-644 ST - Discrepancies in surgical count T2 - AORN Journal TI - Discrepancies in surgical count UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108090999&site=ehost-live&scope=site VL - 88 ID - 850 ER - TY - JOUR AB - Dirofilariasis is a zoonotic infection caused by worms belonging to the genus Dirofilaria. The disease is transmitted by mosquitoes and the hosts are usually dogs. Infections in humans are rare and they usually manifest as a subcutaneous nodule or a conjunctival form. We present a 10-year-old boy with a subcutaneous nodule on his left forearm, who was admitted to the hospital. On examination, the only significant findings were high levels of eosinophils. The pediatrician suspected dirofilariasis and the boy was referred to pediatric surgery. The whole lesion was surgically removed and histopathologic examination confirmed parasitic infection by Dirofilaria repens. Although human dirofilariasis is a rare disease, the number of reported cases has recently increased worldwide. The disease mainly occurs in southern European countries, but has also been described in eastern Europe, Central Asia and Sri Lanka. Croatia is one of the endemic areas for dirofilariasis, especially in the region of the Istria Peninsula. The case presented highlights the requirement for further monitoring of endemic areas in order to establish effective preventive measures. AD - Clinical Department of Pediatric Surgery, Rijeka University Hospital Center, Rijeka, Croatia Department of Pathology, School of Medicine, University of Rijeka, Rijeka University Hospital Center, Rijeka, Croatia Clinical Department of Gynecology and Obstetrics, University of Rijeka, Rijeka University Hospital Center, Rijeka, Croatia Clinical Department of MicrobiologyRijeka, Rijeka University Hospital Center, Rijeka, Croatia AU - Glavan, N. AU - Pećanić, S. AU - Bosak, A. AU - Gačanin, L. AU - Abram, M. AU - Jonjić, N. DB - Scopus IS - 4 KW - Case report Croatia Dirofilaria repens Dirofilariasis Zoonoses M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2015 SP - 533-538 ST - Dirofilaria Repens infection in a TEN-year-old boy from the Istria Peninsula: Case report T2 - Acta Clinica Croatica TI - Dirofilaria Repens infection in a TEN-year-old boy from the Istria Peninsula: Case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84995324125&partnerID=40&md5=d422279980e56851ff9e57045e661a76 VL - 52 ID - 1249 ER - TY - JOUR AB - Purpose: To assess the efficacy and safety of difluprednate ophthalmic emulsion 0.05% (Durezol) 2 or 4 times a day compared with those of a placebo in the treatment of inflammation and pain associated with ocular surgery. Setting: Twenty-six clinics in the United States. Methods: One day after unilateral ocular surgery, patients who had an anterior chamber cell grade of 2 or higher (>10 cells) were treated with 1 drop of difluprednate 2 times or 4 times a day or with a placebo (vehicle) 2 times or 4 times a day in the study eye for 14 days. This was followed by a 14-day tapering period and a 7-day safety evaluation. Outcome measures included cleared anterior chamber inflammation (grade 0, ≤1 cell), absence of pain, and analysis of ocular adverse events. Results: Of the 438 patients, 111 received difluprednate 2 times a day, 107 received difluprednate 4 times a day, and 220 received a placebo 2 or 4 times a day. Both difluprednate dosage regimens reduced postoperative ocular inflammation and pain safely and effectively compared with the placebo. A greater proportion of difluprednate-treated patients had a reduction in inflammation and pain at 8 days and 15 days. Three percent of patients in both difluprednate groups had a clinically significant IOP rise (≥10 mm Hg and ≥21 mm Hg from baseline, respectively) versus 1% in the placebo group. Conclusions: Difluprednate given 2 or 4 times a day cleared postoperative inflammation and reduced pain rapidly and effectively. There were no serious ocular adverse events. Fewer adverse events were reported in the difluprednate-treated groups than in the placebo group. © 2009 ASCRS and ESCRS. AU - Korenfeld, M. S. AU - Silverstein, S. M. AU - Cooke, D. L. AU - Vogel, R. AU - Crockett, R. S. DB - Scopus DO - 10.1016/j.jcrs.2008.09.024 IS - 1 M3 - Article N1 - Cited By :64 Export Date: 10 November 2020 PY - 2009 SP - 26-34 ST - Difluprednate ophthalmic emulsion 0.05% for postoperative inflammation and pain T2 - Journal of Cataract and Refractive Surgery TI - Difluprednate ophthalmic emulsion 0.05% for postoperative inflammation and pain UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-57849084410&doi=10.1016%2fj.jcrs.2008.09.024&partnerID=40&md5=d24ce959b03756846b06013d67ee424d VL - 35 ID - 1507 ER - TY - JOUR AB - BACKGROUND: The purpose of this study was to compare the efficacy and safety of difluprednate 0.05% (PRO-145) versus prednisolone acetate 1% (Prednefrin(®) SF), for management of postoperative inflammation and pain, after cataract surgery. METHODS: This was a Phase III, multicenter, prospective, double-blind, clinical trial. Intent-to-treat population included 178 post-phacoemulsification patients that were assigned to receive either PRO-145, or prednisolone. One day after unilateral eye surgery, patients instilled a drop 4 times a day for 14 days (then tapering the dose downward for 14 days). The primary efficacy endpoints were anterior chamber (AC) cell grade and flare. Other parameters measured included: retinal central thickness (measured via OCT), conjunctival hyperemia, edema, pain and photophobia. Tolerability and safety were assessed through burning, itching, foreign body sensation, visual acuity (VA), intraocular pressure (IOP) and incidence of adverse events (AE). RESULTS: A total of 171 subjects were randomized (1:1) and completed the study. Compared to day 1, there was a significant improvement in the AC cell count and flare in both groups by the final visit (80.2% vs 88.4%, p=1.000). Conjunctival hyperemia improved in a similar fashion (81.2% vs 79%, p=0.234) in both PRO-145 and prednisolone groups, without differences between them. This was also observed for edema (82.4% vs 82.5%, p=0.246), pain (15.3% vs 7%, p=0.497) and photophobia (16.4% vs 15.1%, p=0.246), respectively. There was no significant difference between treatments for any tolerability parameter studied. Finally, at the 4-week postoperative visit, there were no significant differences between treatments for VA, IOP and AE results (p-values; 0.095, 0.053 and 0.099, respectively). CONCLUSION: The results of this study suggest that PRO-145 is as effective and safe as prednisolone acetate in treating postoperative inflammation and pain in patients undergoing phacoemulsification. The study was registered at ClinicalTrials.gov as NCT03693989. AD - Fundación Hospital Nuestra Señora de la Luz, IAP, CDMX, Mexico. Fundación de Asistencia Privada Conde de Valenciana, IAP, CDMX, Mexico. Catarata y Glaucoma de Occidente SA de CV, Guadalajara, Jalisco, Mexico. Private Office, Guadalajara, Jalisco, Mexico. Aris Vision Institute, Guadalajara, Jalisco, Mexico. Asociación Para Evitar la Ceguera en México, IAP, CDMX, Mexico. Visión Cirugía Ambulatoria, Monterrey, Nuevo Leon, Mexico. Medical Affairs, Laboratorios Sophia, SA de CV, Zapopan, Jalisco, Mexico. AN - 32606573 AU - Palacio-Pastrana, C. AU - Chávez-Mondragón, E. AU - Soto-Gómez, A. AU - Suárez-Velasco, R. AU - Montes-Salcedo, M. AU - Fernández de Ortega, L. AU - Nasser-Nasser, L. AU - Baiza-Durán, L. AU - Olvera-Montaño, O. AU - Muñoz-Villegas, P. C2 - PMC7297453 DO - 10.2147/opth.S254705 DP - NLM ET - 2020/07/02 KW - cataract surgery difluprednate dose-reduction ophthalmic corticosteroids no other conflicts of interest in this work. LA - eng N1 - 1177-5483 Palacio-Pastrana, Claudia Orcid: 0000-0002-3366-5645 Chávez-Mondragón, Eduardo Orcid: 0000-0002-3665-0254 Soto-Gómez, Abraham Orcid: 0000-0003-3588-1322 Suárez-Velasco, Rubén Montes-Salcedo, Miguel Fernández de Ortega, Lourdes Nasser-Nasser, Linda Orcid: 0000-0001-7216-1522 Baiza-Durán, Leopoldo Olvera-Montaño, Oscar Orcid: 0000-0003-2717-349x Muñoz-Villegas, Patricia Orcid: 0000-0002-7559-1218 Journal Article Clin Ophthalmol. 2020 Jun 12;14:1581-1589. doi: 10.2147/OPTH.S254705. eCollection 2020. PY - 2020 SN - 1177-5467 (Print) 1177-5467 SP - 1581-1589 ST - Difluprednate 0.05% versus Prednisolone Acetate Post-Phacoemulsification for Inflammation and Pain: An Efficacy and Safety Clinical Trial T2 - Clin Ophthalmol TI - Difluprednate 0.05% versus Prednisolone Acetate Post-Phacoemulsification for Inflammation and Pain: An Efficacy and Safety Clinical Trial VL - 14 ID - 253 ER - TY - JOUR AB - The differentiation of bacterial from aseptic meningitis in postoperative neurosurgical patients has traditionally been based on the clinical setting, a recent history of steroid administration, and cerebrospinal fluid (CSF) studies, including the total and differential leukocyte counts, Gram stain, glucose, and total protein. Recent reports questioning both the validity of a relative CSF lymphocytosis in excluding bacterial meningitis and the usefulness of standard CSF testing prompted the authors to reevaluate these standard criteria. The type of operation, the presence of a foreign body, use of steroids, postoperative day on which symptoms developed, altered mental status, neck stiffness, headache, and nausea were not helpful in the differential diagnosis. High fever, new neurological deficits, an active CSF leak, and elevated leukocyte counts in the CSF and peripheral blood favored a bacterial etiology. The CSF glucose level and the differential leukocyte count were less helpful. No criterion or combination of criteria was sensitive and specific enough to reliably differentiate aseptic from bacterial meningitis in the majority of patients. The possibility of improving diagnostic accuracy with newer tests, such as CSF lactate, ferritin, total amino acids, C-reactive protein, and amyloid-A, should be assessed. AD - Department of Neurological Surgery, School of Medicine, University of California, San Francisco. AN - 3183729 AU - Ross, D. AU - Rosegay, H. AU - Pons, V. DA - Nov DO - 10.3171/jns.1988.69.5.0669 DP - NLM ET - 1988/11/01 IS - 5 KW - *Bacterial Infections/diagnosis/pathology Central Nervous System/*surgery Cerebrospinal Fluid/cytology Diagnosis, Differential Humans Leukocyte Count Meningitis/*diagnosis/*etiology Meningitis, Aseptic/*diagnosis/pathology Neutrophils/pathology *Postoperative Complications LA - eng N1 - Ross, D Rosegay, H Pons, V Journal Article United States J Neurosurg. 1988 Nov;69(5):669-74. doi: 10.3171/jns.1988.69.5.0669. PY - 1988 SN - 0022-3085 (Print) 0022-3085 SP - 669-74 ST - Differentiation of aseptic and bacterial meningitis in postoperative neurosurgical patients T2 - J Neurosurg TI - Differentiation of aseptic and bacterial meningitis in postoperative neurosurgical patients VL - 69 ID - 16 ER - TY - JOUR AB - Monocytes adherent to implanted biomaterials differentiate into macrophages while synthesizing large amounts of degradative enzymes, including cholesterol esterase (CE), which previously has been shown to degrade poly(urethane)s. Human peripheral blood monocytes were cultured on tissue culture grade polystyrene (PS), and two model poly(urethane)s were synthesized from (1) polycaprolactone (PCL) and (2) polytetramethylene oxide (PTMO), both with 2,4-toluene diisocyanate (TDI) and ethylene diamine (ED). The increase in CE and total protein per cell were measured on days 8 and 28 in culture and normalized to the DNA content per cell. At day 8 there consistently were fewer cells remaining on the PTMO-based polymer than on the PCL-based polymer or the PS (p < 0.05). When comparing day 28 to day 8, there was more CE activity and protein per cell on all materials. However, there was a disproportionate synthesis of CE per mg of total protein on PS and TDI/PCL/ED whereas on PTMO there was not. Significantly, there was more protein and CE per cell on PTMO than on PS or TDI/PCL/ED (p < 0.05). This in vitro model system of the chronic phase of inflammation has shown that it is possible to culture monocytes for a month and assess the material surface itself as a potent activator of the differentiation into macrophages without secondary stimulation. Since CE has been shown to degrade poly(ether and ester)-based poly(urethane)s, the differential production of this enzyme relative to the total protein on different surfaces may impact on the potential long-term biostability of an implanted material. Monocytes adherent to implanted biomaterials differentiate into macrophages while synthesizing large amounts of degradative enzymes, including cholesterol esterase (CE), which previously has been shown to degrade poly(urethane)s. Human peripheral blood monocytes were cultured on tissue culture grade polystyrene (PS), and two model poly(urethane)s were synthesized from (1) polycaprolactone (PCL) and (2) polytetramethylene oxide (PTMO), both with 2,4-toluene diisocyanate (TDI) and ethylene diamine (ED). The increase in CE and total protein per cell were measured on days 8 and 28 in culture and normalized to the DNA content per cell. At day 8 there consistently were fewer cells remaining on the PTMO-based polymer than on the PCL-based polymer or the PS (p<0.05). When comparing day 28 to day 8, there was more CE activity and protein per cell on all materials. However, there was a disproportionate synthesis of CE per mg of total protein on PS and TDI/PCL/ED whereas on PTMO there was not. Significantly, there was more protein and CE per cell on PTMO than on PS or TDI/PCL/ED (p<0.05). This in vitro model system of the chronic phase of inflammation has shown that it is possible to culture monocytes for a month and assess the material surface itself as a potent activator of the differentiation into macrophages without secondary stimulation. Since CE has been shown to degrade poly(ether and ester)based poly(urethane)s, the differential production of this enzyme relative to the total protein on different surfaces may impact on the potential long-term biostability of an implanted material. AD - Department of Surgery, University of Ottawa Heart Institute, 1053 Carling Avenue, Ottawa, Ont. K1Y 4E9, Canada Faculty of Dentistry, University of Toronto, Toronto, Ont., Canada AU - Labow, R. S. AU - Meek, E. AU - Santerre, J. P. DB - Scopus DO - 10.1002/(SICI)1097-4636(19980305)39:3<469::AID-JBM18>3.0.CO;2-5 IS - 3 KW - Biodegradation Biostability Cholesterol esterase Monocyte-derived macrophages Poly(urethane)s M3 - Article N1 - Cited By :51 Export Date: 10 November 2020 PY - 1998 SP - 469-477 ST - Differential synthesis of cholesterol esterase by monocyte-derived macrophages cultured on poly(ether or ester)-based poly(urethane)s T2 - Journal of Biomedical Materials Research TI - Differential synthesis of cholesterol esterase by monocyte-derived macrophages cultured on poly(ether or ester)-based poly(urethane)s UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032485208&doi=10.1002%2f%28SICI%291097-4636%2819980305%2939%3a3%3c469%3a%3aAID-JBM18%3e3.0.CO%3b2-5&partnerID=40&md5=e9b4fb7dc98e736954b70f69971ba5cc VL - 39 ID - 1697 ER - TY - JOUR AB - This study investigated the effect of nursing experience on attention allocation and task performance during surgery. The prevention of cases of retained foreign bodies after surgery typically depends on scrub nurses, who are responsible for performing multiple tasks that impose heavy demands on the nurses' cognitive resources. However, the relationship between the level of experiences and attention allocation strategies has not been extensively studied. Eye movement data were collected from 10 novice and 10 experienced scrub nurses in the operating theater for caesarean section surgeries. Visual scanning data, analyzed by dividing the workstation into four main areas and the surgery into four stages, were compared to the optimum expected value estimated by SEEV (Salience, Effort, Expectancy, and Value) model. Both experienced and novice nurses showed significant correlations to the optimal percentage dwell time values, and significant differences were found in attention allocation optimality between experienced and novice nurses, with experienced nurses adhering significantly more to the optimal in the stages of high workload. Experienced nurses spent less time on the final count and encountered fewer interruptions during the count than novices indicating better performance in task management, whereas novice nurses switched attention between areas of interest more than experienced nurses. The results provide empirical evidence of a relationship between the application of optimal visual attention management strategies and performance, opening up possibilities to the development of visual attention and interruption training for better performance. AD - Center of Human Factors and Ergonomics, Systems and Engineering Management Division, School of Mechanical and Aerospace Engineering, Nanyang Technological University. AN - 21942313 AU - Koh, R. Y. AU - Park, T. AU - Wickens, C. D. AU - Ong, L. T. AU - Chia, S. N. DA - Sep DO - 10.1037/a0025171 DP - NLM ET - 2011/09/29 IS - 3 KW - Adult *Attention Clinical Competence Eye Movements Humans *Nursing Staff, Hospital *Operating Rooms *Task Performance and Analysis Workload LA - eng N1 - 1939-2192 Koh, Ranieri Y I Park, Taezoon Wickens, Christopher D Ong, Lay Teng Chia, Soon Noi Journal Article Research Support, Non-U.S. Gov't United States J Exp Psychol Appl. 2011 Sep;17(3):233-46. doi: 10.1037/a0025171. PY - 2011 SN - 1076-898x SP - 233-46 ST - Differences in attentional strategies by novice and experienced operating theatre scrub nurses T2 - J Exp Psychol Appl TI - Differences in attentional strategies by novice and experienced operating theatre scrub nurses VL - 17 ID - 115 ER - TY - JOUR AD - Clinical associate professor, University of Texas Health Science Center, San Antonio, TX AN - 105201447. Language: English. Entry Date: 20100702. Revision Date: 20200708. Publication Type: Journal Article AU - Girard, N. J. DB - ccm DO - 10.1016/j.aorn.2010.02.010 DP - EBSCOhost IS - 5 KW - Endocarditis Health Care Errors Retained Instruments -- Complications Surgical Count Procedure Surgical Sponges Aged Candidiasis Contrast Media -- Therapeutic Use Male Patient Rounds Retained Instruments -- Diagnosis N1 - case study. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PMID: NLM20451008. PY - 2010 SN - 0001-2092 SP - 644-583 ST - Did we forget something? T2 - AORN Journal TI - Did we forget something? UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105201447&site=ehost-live&scope=site VL - 91 ID - 836 ER - TY - JOUR AB - The symptoms of starch peritonitis, a granulomatous reaction to surgical glove powder, may be difficult to distinguish from a complicating bacterial infection and have often led to unnecessary reoperation. This report describes nine suspected cases of starch peritonitis in which the diagnosis was supported by examination of ascitic fluid obtained by paracentesis. Ascitic fluid from these patients was abundant, sterile, and contained mononuclear leucocytes. Starch granules were demonstrated either by iodine staining or by polarised-light microscopy in seven of nine uncentrifuged specimens. Control specimens from ten other postoperative patients contained smaller numbers of mononuclear leucocytes and no starch granules. None of the nine patients with starch peritonitis was re-explored; in each case the peritoneal reaction subsided without complication and did not recur. Although a late postoperative infection must not be lightly dismissed, generally the symptom complex of starch peritonitis is consistent enough to be recognised easily. Examination of ascitic fluid provides a rapid, simple method of confirming the diagnosis and avoiding unnecessary reoperation. © 1972. AD - General Surgical Services, Massachusetts General Hospital, Department of Surgery, Boston, MA, United States AU - Warshaw, AndrewL DB - Scopus DO - 10.1016/S0140-6736(72)92338-0 IS - 7786 M3 - Article N1 - Cited By :20 Export Date: 10 November 2020 PY - 1972 SP - 1054-1056 ST - DIAGNOSIS OF STARCH PERITONITIS BY PARACENTESIS T2 - The Lancet TI - DIAGNOSIS OF STARCH PERITONITIS BY PARACENTESIS UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015515191&doi=10.1016%2fS0140-6736%2872%2992338-0&partnerID=40&md5=5a6899c318d3991d36394183591c2249 VL - 300 ID - 1786 ER - TY - JOUR AB - This study describes the clinical presentation of ruminal and reticular foreign body syndrome (RRFBS), and evaluates the effect of mineral deficiency on its occurrence in dromedary camels. Thirty dromedary camels were divided into two groups. Group 1 (control) included 10 apparently healthy she-camels. Group 2 consisted of twenty dromedary camels diagnosed with RRFBS on the basis of clinical, ultrasonographic, hematological, and biochemical examinations. Clinical findings showed decreased appetite and milk yield, tympany, and gradual body weight loss. Ultrasonographic examinations revealed the presence of hyperechoic material with variable degrees of shadowing. Hematological evaluation showed a significant (P<0.05) decrease of the total erythrocyte and lymphocyte count and a significant increase of neutrophils in the camels with RRFBS compared to the controls. Biochemical tests showed a significant elevation in the activity of serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT), creatine kinase (CK), glucose, creatinine, and blood urea nitrogen and a significant decrease of sodium, chloride, potassium, cobalt, iron, and selenium in the camels with RRFBS compared to the controls. Rumenotomy was performed on the 20 camels as a surgical intervention for treating the RRFBS. By the 6th month postoperatively, all surgically treated camels had completely recovered except for one with tympany and slight swelling in situ. In conclusion, trace element deficiency might play an important role in the occurrence of foreign body ingestion syndrome in dromedary camels. Moreover, clinical, ultrasonographic, hematological, and biochemical examinations are considered as tools assisting in the accurate diagnosis, prognosis, and treatment stratagem for RRFBS in camels. AD - Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Qassim University, Qassim, P.O. Box 51452, Saudi Arabia. Department of Surgery, Anesthesiology and Radiology, Faculty of Veterinary Medicine, South Valley University, Qena 83523, Egypt. Department of Surgery, Anesthesiology and Radiology, Faculty of Veterinary Medicine, Mansoura University, Mansoura 35516, Egypt. AN - 32507784 AU - Sadan, M. AU - El-Shafaey, E. S. AU - Al-Sobayil, F. C2 - PMC7468058 DA - Aug 19 DO - 10.1292/jvms.19-0621 DP - NLM ET - 2020/06/09 IS - 8 KW - camel foreign body mineral deficiency rumenotomy ultrasonography LA - eng N1 - 1347-7439 Sadan, Madeh El-Shafaey, El-Sayed Al-Sobayil, Fahd Journal Article J Vet Med Sci. 2020 Aug 19;82(8):1097-1103. doi: 10.1292/jvms.19-0621. Epub 2020 Jun 8. PY - 2020 SN - 0916-7250 (Print) 0916-7250 SP - 1097-1103 ST - Diagnosis and treatment of foreign bodies swallowing syndrome in camels (Camelus dromedarius) with special reference to the role of mineral deficiency T2 - J Vet Med Sci TI - Diagnosis and treatment of foreign bodies swallowing syndrome in camels (Camelus dromedarius) with special reference to the role of mineral deficiency VL - 82 ID - 251 ER - TY - JOUR AB - Objectives/Hypothesis: Aortoesophageal fistula is a rare but life-threatening complication of foreign body ingestion. In spite of several strategies for treatment, there is little consensus regarding the optimal management of the entity. In this article, we present our experience in the diagnosis and treatment of patients with aortoesophageal fistula. Study Design: Retrospective study. Methods: A total of 3,209 admissions due to esophageal foreign body impaction were recorded in Second Xiangya Hospital between 1963 and 2010. Of these, 32 cases were complicated with aortoesophageal fistula. In these 32 patients, 19 were treated by open surgery and 13 were managed with nonsurgical measures. We compared different treatments of the patients and their clinical outcomes. Results: Foreign body and aortoesophageal fistula were found in all of these 32 cases in imaging examination and/or surgery. Three patients were completely cured and 16 patients died of fatal hemorrhage from the group of patients with surgical management. All 13 nonsurgically treated cases died. Conclusions: Early diagnosis and an aggressive surgical treatment without delay is the only form of effective therapy for the condition of aortoesophageal fistula. Imaging examination is helpful in diagnosis. In particular, three-dimensional computerized tomography is a safe, simple, and noninvasive examination method that has high sensitivity and specificity for the early diagnosis of aortoesophageal fistula. © 2011 The American Laryngological, Rhinological, and Otological Society, Inc. AD - Department of Otolaryngology-Head and Neck Surgery, Second Xiangya Hospital, Central South University, No.139 Middle Ren-Min Road, Changsha Hunan, 410011, China Department of Cardiothoracic Surgery, Second Xiangya Hospital, Central South University, China AU - Zhang, X. AU - Liu, J. AU - Li, J. AU - Hu, J. AU - Yu, F. AU - Li, S. AU - Yang, X. DB - Scopus DO - 10.1002/lary.21366 IS - 2 KW - aortic disease aortoesophageal fistula Esophageal foreign body Level of Evidence: 4 M3 - Article N1 - Cited By :23 Export Date: 10 November 2020 PY - 2011 SP - 267-272 ST - Diagnosis and treatment of 32 cases with aortoesophageal fistula due to esophageal foreign body T2 - Laryngoscope TI - Diagnosis and treatment of 32 cases with aortoesophageal fistula due to esophageal foreign body UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79251555654&doi=10.1002%2flary.21366&partnerID=40&md5=ea563defa7d2a5eb038b560f080745ac VL - 121 ID - 1427 ER - TY - JOUR AB - We reviewed 27 patients who underwent revision for an adverse local tissue reaction (ALTR) secondary to corrosion at the head-neck junction with MoP bearings. Serum cobalt and chromium levels were elevated in all cases, with a mean cobalt of 11.2 ppb and chromium of 2.2 ppb. Patients underwent modular bearing exchange, including a ceramic head with a titanium sleeve in 23 of 27 cases with only one recurrence of ALTR in one of the four patients not treated with a ceramic head. The diagnosis of ALTR secondary to corrosion is associated with cobalt levels of >1 ppb with cobalt levels elevated above chromium. Retention of a well-fixed stem and modular exchange to a ceramic head leads to resolution of symptoms and decreases in metal levels. © 2016 Elsevier Inc. AD - Department of Orthopaedic Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, United States Orthopaedic Surgery, Midwest Orthopaedics at Rush, Chicago, IL, United States AU - Plummer, D. R. AU - Berger, R. A. AU - Paprosky, W. G. AU - Sporer, S. M. AU - Jacobs, J. J. AU - Della Valle, C. J. DB - Scopus DO - 10.1016/j.arth.2015.07.039 IS - 1 KW - Adverse local tissue reaction Bearing surfaces Modular taper corrosion Revision total hip arthroplasty Total hip arthroplasty M3 - Article N1 - Cited By :99 Export Date: 10 November 2020 PY - 2016 SP - 264-268 ST - Diagnosis and Management of Adverse Local Tissue Reactions Secondary to Corrosion at the Head-Neck Junction in Patients With Metal on Polyethylene Bearings T2 - Journal of Arthroplasty TI - Diagnosis and Management of Adverse Local Tissue Reactions Secondary to Corrosion at the Head-Neck Junction in Patients With Metal on Polyethylene Bearings UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84940062247&doi=10.1016%2fj.arth.2015.07.039&partnerID=40&md5=309edbbb7bfc6c268e649710824767b0 VL - 31 ID - 1210 ER - TY - JOUR AB - Background: A small percentage of patients with foreign body ingestion develop complications, which have a variety of clinical presentations. Less than 1% of cases require surgical intervention. We present a patient with an abdominal wall abscess resulting from a fish bone that pierced the cecum. The patient was treated laparoscopically. Case presentation: A 55-year-old Japanese man presented to our hospital with a complaint of right lower abdominal pain. A physical examination revealed tenderness, swelling, and redness at the right iliac fossa. Computed tomography showed a low-density area with rim enhancement in his right internal oblique muscle and a hyperdense 20 mm-long pointed object in the wall of the adjacent cecum. Based on the findings we suspected an abdominal wall abscess resulting from a migrating ingested fish bone. He was administered antibiotics as conservative treatment, and the abscess was not seen on subsequent computed tomography. Two months after the initial treatment, he presented with the same symptoms, and a computed tomography scan showed the foreign body in the same location as before with the same low-density area. We diagnosed the low-density area as recurrence of the abdominal wall abscess. He underwent laparoscopic surgery to remove the foreign body. His appendix, and part of his cecum and the parietal peritoneum that included the foreign body, were resected. He had an uneventful postoperative course, and at 1 year after the surgery, the abdominal wall abscess had not recurred. Conclusions: An abdominal wall abscess developed in association with the migration of an ingested fish bone. We suggest that a laparoscopic surgical resection of the portion of the bowel that includes the foreign body is a useful option for selected cases. © 2019 The Author(s). AD - Department of Surgery, Yachiyo Hospital, 2-2-7, Sumiyoshi-cho, Anjo-shi Aichi, 446-8510, Japan Department of Pathology, Yachiyo Hospital, 2-2-7, Sumiyoshi-cho, Anjo-shi Aichi, 446-8510, Japan AU - Kuwahara, K. AU - Mokuno, Y. AU - Matsubara, H. AU - Kaneko, H. AU - Shamoto, M. AU - Iyomasa, S. C7 - 369 DB - Scopus DO - 10.1186/s13256-019-2301-7 IS - 1 KW - Abdominal wall abscess Fish bone Foreign body ingestion Laparoscopic surgery M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2019 ST - Development of an abdominal wall abscess caused by fish bone ingestion: A case report T2 - Journal of Medical Case Reports TI - Development of an abdominal wall abscess caused by fish bone ingestion: A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076546923&doi=10.1186%2fs13256-019-2301-7&partnerID=40&md5=1e2b12cba6f4ae78d2b2781b66c1754f VL - 13 ID - 988 ER - TY - JOUR AB - Background. Retention of surgical sponges in patients is a relatively frequent medical malpractice. To prevent it, the surgical sites are scanned using X-ray. However, using radiography in the operation room induces X-ray exposure for both patients and staff. To prevent such issues, a novel sponge counting system was developed. Each surgical sponge used in common hospitals is composed of single radiopaque fibers. Methods. The proposed system scans surgical sponges to estimate their fiber length (EFL) and returns the number of it. In this study, an optimal image acquisition protocol was determined that allows an accurate count of sponges. X-ray doses and multi-angle image procedures were tested. Results. Measurement trials were performed and compared for both dry and blood-soaked sponges. As a result, the X-ray dose of 50 kV and 600 μA and the acquisition of 180 images per sample yielded an accurate EFL. The 180-image protocol achieved good performance in this study and allowed counting of one package of 10 sponges in 226 seconds. For these settings, a significant correlation was found between the actual number of sponges and the estimated fiber lengths. Additionally, the performance of the system was similar for either dry or blood-soaked items. Conclusion. The proposed system could accurately count surgical sponges and is a promising option in preventing the accidental retention of surgical sponges. AD - K. Yamashita, Faculty of Health Sciences, Ryotokuji University, Chiba, Japan AU - Kusuda, K. AU - Yamashita, K. AU - Tanaka, S. AU - Tanaka, K. AU - Ohta, Y. DB - Embase Medline DO - 10.1177/1553350620943349 KW - adult article controlled study human operating room radiography surgical sponge LA - English M3 - Article in Press N1 - L2005721125 PY - 2020 SN - 1553-3514 1553-3506 ST - Development of a Surgical Sponge Counting System Using Radiographic Images T2 - Surgical Innovation TI - Development of a Surgical Sponge Counting System Using Radiographic Images UR - https://www.embase.com/search/results?subaction=viewrecord&id=L2005721125&from=export http://dx.doi.org/10.1177/1553350620943349 ID - 295 ER - TY - JOUR AB - BACKGROUND: Surgical infections cause substantial morbidity and mortality in low-and middle-income countries (LMICs). To improve adherence to critical perioperative infection prevention standards, we developed Clean Cut, a checklist-based quality improvement program to improve compliance with best practices. We hypothesized that process mapping infection prevention activities can help clinicians identify strategies for improving surgical safety. STUDY DESIGN: We introduced Clean Cut at a tertiary hospital in Ethiopia. Infection prevention standards included skin antisepsis, ensuring a sterile field, instrument decontamination/sterilization, prophylactic antibiotic administration, routine swab/gauze counting, and use of a surgical safety checklist. Processes were mapped by a visiting surgical fellow and local operating theater staff to facilitate the development of contextually relevant solutions; processes were reassessed for improvements. RESULTS: Process mapping helped identify barriers to using alcohol-based hand solution due to skin irritation, inconsistent administration of prophylactic antibiotics due to variable delivery outside of the operating theater, inefficiencies in assuring sterility of surgical instruments through lack of confirmatory measures, and occurrences of retained surgical items through inappropriate guidelines, staffing, and training in proper routine gauze counting. Compliance with most processes improved significantly following organizational changes to align tasks with specific process goals. CONCLUSIONS: Enumerating the steps involved in surgical infection prevention using a process mapping technique helped identify opportunities for improving adherence and plotting contextually relevant solutions, resulting in superior compliance with antiseptic standards. Simplifying these process maps into an adaptable tool could be a powerful strategy for improving safe surgery delivery in LMICs. AD - Department of Surgery, Stanford University, Stanford, CA; Lifebox Foundation, Ariadne Labs, Brigham. Electronic address: jaredf2@stanford.edu. Lifebox Foundation, Ariadne Labs, Brigham. Department of Obstetrics and Gynecology, School of Medicine, College of Health Sciences, Jimma University, Jimma, Ethiopia. Lifebox Foundation, Ariadne Labs, Brigham; Women's Hospital and the Harvard TH Chan School of Public Health, Boston, MA; Department of Surgery, Massachusetts General Hospital, Boston, MA. Lifebox Foundation, Ariadne Labs, Brigham; Women's Hospital and the Harvard TH Chan School of Public Health, Boston, MA. Department of Surgery, School of Medicine, College of Health Sciences, Jimma University, Jimma, Ethiopia. Department of Health Economics, Management, and Policy, Jimma University Medical Center, Jimma, Ethiopia. Department of Surgery, Stanford University, Stanford, CA; Lifebox Foundation, Ariadne Labs, Brigham; Department of Clinical Surgery, Royal Infirmary of Edinburgh, University of Edinburgh, Edinburgh, UK. AN - 29574175 AU - Forrester, J. A. AU - Koritsanszky, L. A. AU - Amenu, D. AU - Haynes, A. B. AU - Berry, W. R. AU - Alemu, S. AU - Jiru, F. AU - Weiser, T. G. DA - Jun DO - 10.1016/j.jamcollsurg.2018.03.020 DP - NLM ET - 2018/03/27 IS - 6 KW - Anti-Infective Agents, Local/therapeutic use Antibiotic Prophylaxis Checklist Ethiopia *Health Resources Hospitals, Teaching Humans *Process Assessment, Health Care Prospective Studies Protective Clothing *Quality Improvement Sterilization/standards Surgical Wound Infection/*prevention & control LA - eng N1 - 1879-1190 Forrester, Jared A Koritsanszky, Luca A Amenu, Demisew Haynes, Alex B Berry, William R Alemu, Seifu Jiru, Fekadu Weiser, Thomas G Journal Article Research Support, Non-U.S. Gov't United States J Am Coll Surg. 2018 Jun;226(6):1103-1116.e3. doi: 10.1016/j.jamcollsurg.2018.03.020. Epub 2018 Mar 21. PY - 2018 SN - 1072-7515 SP - 1103-1116.e3 ST - Developing Process Maps as a Tool for a Surgical Infection Prevention Quality Improvement Initiative in Resource-Constrained Settings T2 - J Am Coll Surg TI - Developing Process Maps as a Tool for a Surgical Infection Prevention Quality Improvement Initiative in Resource-Constrained Settings VL - 226 ID - 210 ER - TY - JOUR AB - BACKGROUND: While the true incidence of retained foreign bodies after surgery is unknown, it has been approximated at 1:5,500 operations overall, with substantially less frequency in hand and upper extremity procedures. Despite the rarity of foreign body retention in hand and upper extremity surgery, universal radiofrequency scanning for electronically-tagged sponges and automatic radiographic evaluation for incorrect sponge counts are employed for all surgical procedures at our institution. We demonstrate the infeasibility of retaining an operative sponge of a standard size in commonly performed hand and upper extremity procedures with incision sizes of two centimeters or less, and establish that visual detection of sponges in these cases is adequate. METHODS: Eighteen trigger finger releases, five carpal tunnel releases, three trigger thumb releases, and three de Quervain's tenosynovitis releases were successfully performed upon five cadaveric specimens by residents under supervision of fellowship-trained hand surgeons for a total of 29 two-centimeter or smaller incisions. Randomized surgical sponge placement was evaluated by a blinded observer at two distances and incision sizes were quantified. Kappa values were calculated to determine the acuity of visual detection versus the actual presence of a sponge. RESULTS: The maximum length of the standard surgical sponge that could be contained within an incision was three centimeters. When compared with the gold standard (whether the sponge had been placed or not by the operating resident), the placement of a standard surgical sponge could be detected correctly in 100% of cases at both "across the room" and "at the table" distances, for kappa values of 1.0 and 1.0 respectively. This did not vary with incision size or surgical procedure. CONCLUSIONS: The added cost and time from radiofrequency detection of retained sponges and radiographic evaluation in the event of incorrect sponge counts can be safely eliminated if sponges can be reliably visually detected. CLINICAL RELEVANCE: This cadaveric study informs patient safety practices by demonstrating that visual detection of surgical sponges is adequate for certain upper extremity procedures. AD - University of Iowa Hospitals and Clinics Department of Orthopaedics and Rehabilitation. AN - 28852356 AU - Tofte, J. N. AU - Caldwell, L. S. C2 - PMC5508279 DP - NLM ET - 2017/08/31 KW - Foreign Bodies/*diagnosis Humans Orthopedic Procedures/*adverse effects *Surgical Sponges Upper Extremity/*surgery *hand *patient safety *quality improvement *radiofrequency *retained foreign body *retained foreign object *upper extremity LA - eng N1 - 1555-1377 Tofte, Josef N Caldwell, Lindsey S Journal Article Iowa Orthop J. 2017;37:189-192. PY - 2017 SN - 1541-5457 (Print) 1541-5457 SP - 189-192 ST - Detection of Retained Foreign Objects in Upper Extremity Surgical Procedures With Incisions of Two Centimeters or Smaller T2 - Iowa Orthop J TI - Detection of Retained Foreign Objects in Upper Extremity Surgical Procedures With Incisions of Two Centimeters or Smaller VL - 37 ID - 198 ER - TY - JOUR AB - BACKGROUND: The Agency for Healthcare Research and Quality (AHRQ) developed patient safety indicator (PSI) 5, "Foreign body left during procedure," to flag accidental foreign bodies in surgical and medical procedures. This study examined how well this indicator identifies true foreign body events in the Veterans Health Administration (VA). STUDY DESIGN: This was a retrospective study within 28 selected VA hospitals from fiscal year 2003 to 2007. Trained abstractors reviewed medical charts flagged by PSI 5 and determined true foreign body cases. We calculated the positive predictive value (PPV) of this indicator and performed descriptive analyses of true positive and false positive cases. RESULTS: Of the 652,093 eligible cases, 93 were flagged by PSI 5 (0.14 per 1,000). Forty-two were true positives, yielding a PPV of 45% (95% CI 35% to 56%). False positives were due to a foreign body that was present on admission (57%) or coding errors (43%). True foreign bodies were associated with surgical (n = 23) and medical (n = 19) procedures. The most common type of surgical foreign body was a sponge (52%). Overall, approximately 40% of foreign bodies were related to a device failure or malfunction (30% surgical vs 53% medical foreign bodies). Postoperative complications included pain (24%), infection (12%), adhesions (5%), and bowel obstruction (5%). CONCLUSIONS: The reported rate of foreign body events as detected by PSI 5 is low in the VA, but occurs in both surgical and medical procedures. Despite widespread implementation of surgical counts, quality improvement efforts should focus on novel ways to eliminate this "never event" from operations. Future studies are needed to better understand the preventability of medical procedure-associated foreign bodies and particularly, device failure-related foreign bodies. AD - Center for Organization, Leadership, and Management Research (COLMR), Boston, MA, USA. AN - 21489830 AU - Chen, Q. AU - Rosen, A. K. AU - Cevasco, M. AU - Shin, M. AU - Itani, K. M. AU - Borzecki, A. M. DA - Jun DO - 10.1016/j.jamcollsurg.2011.02.003 DP - NLM ET - 2011/04/15 IS - 6 KW - Aged Clinical Coding/standards Confounding Factors, Epidemiologic Cross-Sectional Studies False Positive Reactions Female Foreign Bodies/complications/diagnosis/*epidemiology/etiology/prevention & control Health Services Research Hospitals, Veterans/*statistics & numerical data Humans Inpatients Male Medical Errors/prevention & control/statistics & numerical data Medical Records Systems, Computerized Middle Aged Postoperative Complications/diagnosis/*epidemiology/prevention & control Predictive Value of Tests Quality Indicators, Health Care/*standards/trends Reproducibility of Results Research Design Retrospective Studies Risk Factors Safety Management/*standards Treatment Outcome United States/epidemiology LA - eng N1 - 1879-1190 Chen, Qi Rosen, Amy K Cevasco, Marisa Shin, Marlena Itani, Kamal M F Borzecki, Ann M Evaluation Study Journal Article Multicenter Study Research Support, U.S. Gov't, Non-P.H.S. United States J Am Coll Surg. 2011 Jun;212(6):977-83. doi: 10.1016/j.jamcollsurg.2011.02.003. Epub 2011 Apr 13. PY - 2011 SN - 1072-7515 SP - 977-83 ST - Detecting patient safety indicators: How valid is "foreign body left during procedure" in the Veterans Health Administration? T2 - J Am Coll Surg TI - Detecting patient safety indicators: How valid is "foreign body left during procedure" in the Veterans Health Administration? VL - 212 ID - 107 ER - TY - JOUR AB - The use of spinal cord stimulation (SCS) devices to treat chronic, refractory neuropathic pain continues to expand in application. While device-related complications have been well described, inflammatory reactions to the components of these devices remain underreported. In contrast, hypersensitivity reactions associated with other implanted therapies, such as endovascular and cardiac rhythm devices, have been detailed. The purpose of this case series is to describe the clinical presentation and course of inflammatory reactions as well as the histology of these reactions. All patients required removal of the entire device after developing inflammatory reactions over a time course of 1-3 months. Two patients developed a foreign body reaction in the lead insertion wound as well as at the implantable pulse generator site, with histology positive for giant cells. One patient developed an inflammatory dermatitis on the flank and abdomen that resolved with topical hydrocortisone. "In vivo" testing with a lead extension fragment placed in the buttock resulted in a negative reaction followed by successful reimplantation of an SCS device. Inflammatory reactions to SCS devices can manifest as contact dermatitis, granuloma formation, or foreign body reactions with giant cell formation. Tissue diagnosis is essential, and is helpful to differentiate an inflammatory reaction from infection. The role of skin patch testing for 96 hours may not be suited to detect inflammatory giant cell reactions that manifest several weeks post implantation. © 2013 Chaudhry et al, publisher and licensee Dove Medical Press Ltd. AD - Department of Diagnostic and Interventional Neuroradiology, Massachusetts General Hospital/ Harvard Medical School, Boston, MA, United States Department of Neurology, Robert C Byrd Health Sciences Center of West Virginia University, Morgantown, WV, United States Boston Headache Institute, Waltham, MA, United States Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States Department of Medicine, Allergy and Immunology, Brookline, MA, United States Department of Anesthesia, Beth Israel Deaconess Medical Center, Brookline, MA, United States AU - Chaudhry, Z. A. AU - Najib, U. AU - Bajwa, Z. H. AU - Jacobs, W. C. AU - Sheikh, J. AU - Simopoulos, T. T. DB - Scopus DO - 10.2147/JPR.S44676 KW - Contact dermatitis Delayed inflammatory responses Foreign body giant cell reactions Spinal cord stimulation M3 - Article N1 - Cited By :11 Export Date: 10 November 2020 PY - 2013 SP - 617-623 ST - Detailed analysis of allergic cutaneous reactions to spinal cord stimulator devices T2 - Journal of Pain Research TI - Detailed analysis of allergic cutaneous reactions to spinal cord stimulator devices UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84881262111&doi=10.2147%2fJPR.S44676&partnerID=40&md5=5955df768fc6eac72772e31b91c49542 VL - 6 ID - 1311 ER - TY - JOUR AB - A retained surgical sponge is a sentinel event that can result in serious negative outcomes for the patient. Current standards rely on manual counting, the accuracy of which may be suspect, yet little is known about why counting fails to prevent retained sponges. The objectives of this project were to describe perioperative processes to prevent retained sponges after elective abdominal surgery; to identify potential failures; and to rate the causes, probability, and severity of these failures. A total of 57 potential failures were identified, associated with room preparation, the initial count, adding sponges, removing sponges, the first closing count, and the final closing count. The most frequently identified causes of failures included distraction, multitasking, not following procedure, and time pressure. Most of the failures are not likely to be affected by an educational intervention, so additional technological controls should be considered in efforts to improve safety. AD - Center for Comprehensive Access & Delivery Research, VA Iowa City Health Care System, Iowa City, USA. AN - 21802540 AU - Steelman, V. M. AU - Cullen, J. J. DA - Aug DO - 10.1016/j.aorn.2010.09.034 DP - NLM ET - 2011/08/02 IS - 2 KW - Hospitals, Veterans Humans Illinois Iowa *Safety Management Sentinel Surveillance *Surgical Sponges LA - eng N1 - 1878-0369 Steelman, Victoria M Cullen, Joseph J I01 BX001318/BX/BLRD VA/United States Journal Article Research Support, Non-U.S. Gov't United States AORN J. 2011 Aug;94(2):132-41. doi: 10.1016/j.aorn.2010.09.034. PY - 2011 SN - 0001-2092 SP - 132-41 ST - Designing a safer process to prevent retained surgical sponges: a healthcare failure mode and effect analysis T2 - Aorn j TI - Designing a safer process to prevent retained surgical sponges: a healthcare failure mode and effect analysis VL - 94 ID - 110 ER - TY - JOUR AB - Mis-swallowing of a foreign body in the esophagus coexisting with sliding hernia might be misdiagnosed as esophageal perforation with mediastinal abscess. We report an 89-year-old woman, bedridden for a long period in a nursing home after a previous cerebrovascular accident, who was sent to our emergency department in a state of sepsis because she had swallowed a radio-opaque partial denture. The retention of the denture as an esophageal foreign body was complicated with mediastinitis and bilateral pleural effusion. The inability of the patient to give a reliable clinical history delayed the diagnosis. This report highlights the difficulty in precisely locating a partial denture because of conflicting radiologic findings and the coexistence of esophageal sliding hernia, all of which led to a misdiagnosis of possible esophageal perforation. A right posterolateral thoracotomy with gastrostomy was performed to remove the lower esophageal foreign body after esophagoscopy failed. The surgical finding of a coincidental sliding esophageal hiatal hernia correlated well with the clinical presentation. Managing such a complicated esophageal foreign body in this elderly patient was challenging. 2©008 Elsevier & Formosan Medical Association. AD - Division of Thoracic Surgery, Department of Surgery, Tri-Service General Hospital, 325, Section 2, Cheng-Kung Road, Neihu 114 Taipei, Taiwan Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, 325, Section 2, Cheng-Kung Road, Neihu 114 Taipei, Taiwan AU - Chen, C. Y. AU - Lee, S. C. AU - Chen, C. W. AU - Chen, J. C. DB - Scopus DO - 10.1016/S0929-6646(08)60185-0 IS - 8 KW - Esophageal foreign body Partial denture Sliding esophageal hiatal hernia M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2008 SP - 663-666 ST - Denture mis-swallowing in the sliding esophageal hiatal hernia mimics esophageal perforation T2 - Journal of the Formosan Medical Association TI - Denture mis-swallowing in the sliding esophageal hiatal hernia mimics esophageal perforation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-52949126910&doi=10.1016%2fS0929-6646%2808%2960185-0&partnerID=40&md5=091770429087187db2b53b94593c3f61 VL - 107 ID - 1539 ER - TY - JOUR AB - Small-bowel obstruction due to foreign bodies is unusual in adults. Intestinal obstruction is occasionally caused by pits, bezoars, endoscopy capsules, and gastrostomy tube buttons. We report a rare case of distal small-bowel obstruction due to dental impression material. Avoidance of this potentially life-threatening complication may be achieved by increased vigilance in accounting for all impression material when dental impression trays are removed. Early detection of swallowed dental material may afford endoscopic removal from the stomach, thus preventing intestinal obstruction. AD - Department of Surgery, Meharry Medical College, Nashville, TN, United States AU - Dent, L. AU - Peterson, A. AU - Pruett, D. AU - Beech, D. DB - Scopus DO - 10.1016/S0027-9684(15)31143-3 IS - 12 KW - Intestines Obstruction M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2009 SP - 1295-1296 ST - Dental impression material: A rare cause of small-bowel obstruction T2 - Journal of the National Medical Association TI - Dental impression material: A rare cause of small-bowel obstruction UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-75149160963&doi=10.1016%2fS0027-9684%2815%2931143-3&partnerID=40&md5=0bbdb824fa4d1e4e88f28dbbcf0e653d VL - 101 ID - 1503 ER - TY - JOUR AD - Department of Cardiology, Sun Yat-Sen University, Guangzhou 510120, China AU - Yang, L. AU - Wang, J. F. AU - Wu, W. DB - Scopus DO - 10.1097/00029330-200703010-00019 IS - 5 KW - Echocardiography Endocarditis Foreign body M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2007 SP - 437-440 ST - Delayed Serratia marcescens endocarditis associated with intracardiac foreign body T2 - Chinese Medical Journal TI - Delayed Serratia marcescens endocarditis associated with intracardiac foreign body UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33947702207&doi=10.1097%2f00029330-200703010-00019&partnerID=40&md5=750dd622bfb0af8e8692cf11e023bd9f VL - 120 ID - 1567 ER - TY - JOUR AB - Impalement injuries from falls are rarely seen in emergency unit because many patients die at the scene of the accident. These injuries result in high energy transfer between the impaled foreign object and the patient and demonstrate characteristics of both blunt and penetrating trauma. We present an unusual case of delayed presentation of sigmoid colon fistula and psoas. AD - Department of Surgery, University Hospital, Lausanne, Switzerland Service de Chirurgie, CHUV, 1011 Lausanne, Switzerland AU - Vuilleumier, H. AU - Saucy, F. AU - Halkic, N. DB - Scopus IS - 4 KW - Abdominal injury Colon perforation Fistula Impalement Psoas abscess M3 - Article N1 - Export Date: 10 November 2020 PY - 2006 SP - 297-298 ST - Delayed presentation of sigmoid colon fistula 2 years after impalement injury T2 - Chirurgia TI - Delayed presentation of sigmoid colon fistula 2 years after impalement injury UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33846593416&partnerID=40&md5=cd956937b08e95e38676cd8f54300d45 VL - 19 ID - 1580 ER - TY - JOUR AB - Postoperative reaction and infection after anterior cruciate ligament (ACL) reconstruction is a rare complication. We report two cases of bioabsorbable screw extrusion and Pseudomonas aeruginosa tibial tunnel infection in 17/18-year-old men, 2 and 4 years after ACL reconstruction, respectively. They underwent tibial tunnel debridement, removal of the still intact poly-L-D-lactic acid bioabsorbable screw and subsequent wound closure. Physical examination findings confirmed patency of the hamstring graft. Culture guided antibiotics were completed, and wounds healed unremarkably. Both returned to previous level of activity. Successful treatment is achieved through a logical sequence of management, as well as a multidisciplinary approach to prevent unnecessary secondary procedures and morbidity. © 2019 BMJ Publishing Group Limited. No commercial re-use. See rights and permissions. Published by BMJ. AD - Department of Orthopedics, University of the Philippines Manila, Ermita, Manila, Metro Manila, Philippines Department of Internal Medicine, Infectious Disease Service, Philippine General Hospital, University of the Philippines, Manila City, Philippines AU - Dumlao, P. E. AU - Paner, N. AU - Bathan, L. AU - Lim, B. A. C7 - e229927 DB - Scopus DO - 10.1136/bcr-2019-229927 IS - 9 KW - bone and joint infections orthopaedics unwanted effects/adverse reactions M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 ST - Delayed onset bioabsorbable screw reaction, intact screw extrusion and Pseudomonas aeruginosa tibial tunnel osteomyelitis years after arthroscopic anterior cruciate ligament reconstruction using hamstring graft T2 - BMJ Case Reports TI - Delayed onset bioabsorbable screw reaction, intact screw extrusion and Pseudomonas aeruginosa tibial tunnel osteomyelitis years after arthroscopic anterior cruciate ligament reconstruction using hamstring graft UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85072381267&doi=10.1136%2fbcr-2019-229927&partnerID=40&md5=8a4664fb480c8a49028e728d4656761c VL - 12 ID - 1000 ER - TY - JOUR AN - 106258573. Language: English. Entry Date: 20070330. Revision Date: 20150818. Publication Type: Journal Article AU - Burlingame, B. L. DB - ccm DO - 10.1016/S0001-2092(07)60025-8 DP - EBSCOhost IS - 1 KW - Bulletin Boards Surgical Count Procedure Uniforms Venous Thrombosis -- Prevention and Control AORN Communication Compression Garments Documentation Medical Records Nursing Role Operating Rooms N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2007 SN - 0001-2092 SP - 189-192 ST - Deep vein thrombosis; cloth hats; corkboards in the OR; count sheets in charts T2 - AORN Journal TI - Deep vein thrombosis; cloth hats; corkboards in the OR; count sheets in charts UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106258573&site=ehost-live&scope=site VL - 85 ID - 799 ER - TY - JOUR AB - Objectives/Hypothesis To characterize deep neck infections (DNI) in adult intravenous drug users (IDUs) who injected illicit substances to their neck, in comparison to DNI in non-IDUs. Study Design Retrospective, cohort study. Methods Data were retrieved from medical charts of adult DNI patients in a secondary hospital during 2000-2013. Clinical, radiologic, and microbial data were extracted and tabulated following categorization into 2 patient groups: IDUs and non-IDUs. Results Of the 136 patients identified with DNI, 20 (15%) were IDUs; of them 80% were males. IDUs were significantly younger than non-IDUs (mean age, 35-‰±-‰10 vs. 44-‰±-‰16 years, P-‰=-‰.01). All IDUs had multiple comorbidities. IDUs presented for medical examination and hospitalization later in the course of their disease, and the most common involved neck spaces were consistent with areas where cervical injections are commonly performed. Abscess formation was more common in IDUs than non-IDUs (16 [80%] vs. 79 [68%], respectively, P-‰=-‰.04). Despite later presentation of IDUs and their higher rate of comorbidities, laboratory data, microbiology cultures, and disease course were similar to non-IDUs. Conclusions Although IDU and non-IDU differ in DNI presentation, both groups had good outcomes. DNI in IDUs frequently evolved into abscesses, and most were found in the anterior triangle deep to sternocleidomastoid (SCM), posterior triangle, and anterior triangle superficial to SCM, in concordance with the injection sites. © 2014 The American Laryngological, Rhinological and Otological Society, Inc. AD - Department of Otolaryngology-Head and Neck Surgery, Edith Wolfson Medical Center, Tel Aviv University Sackler School of Medicine, P.O. Box 5, Holon, 58100, Israel AU - Tamir, S. O. AU - Marom, T. AU - Len, A. AU - Gluck, O. AU - Goldfarb, A. AU - Roth, Y. DB - Scopus DO - 10.1002/lary.25015 IS - 6 KW - complication Deep neck infection foreign body hepatitis C virus intravenous drugs users M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2015 SP - 1336-1339 ST - Deep neck infections in cervical injection drug users T2 - Laryngoscope TI - Deep neck infections in cervical injection drug users UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84929692425&doi=10.1002%2flary.25015&partnerID=40&md5=51aa164f428282a67731f697a053f755 VL - 125 ID - 1252 ER - TY - JOUR AB - The study aims to present our experience of the clinical course and management of deep neck infection and try to determine if the characteristics of this kind of infection were similar between the children and adults in southern China. Patients diagnosed with deep neck infection in the Division of Otolaryngology in the First Affiliated Hospital of Sun Yat-sen University between January 2002 and December 2011 were screened retrospectively for demographic characteristics, presenting symptoms, antibiotic therapy before admission, the history of antibiotics abuse, leucocyte count, etiology, bacteriology, disease comorbidity, imaging, treatment, complications, and outcomes. One hundred thirty patients were included and 44 (33.8%) were younger than 18 years old (the children group), 86 patients (66.2%) were older than 18 years old (the adults group). Fever, trismus, neck pain, and odynophagia were the most common symptoms in both groups. Forty children (90.9%) and 49 adults (57.0%) had been treated with broad-spectrum antibiotic therapy before admission. Thirty one children (70.5%) and 24 adults (27.9%) had a history of antibiotics abuse. In children group, the site most commonly involved was the parapharyngeal space (18 patients, 40.9%). In adults group, the site most commonly involved was multispace (30 patients, 34.9%). In children group, the most common cause was branchial cleft cyst (5 patients, 11.4%) and the cause remained unknown in 31 patients (70.5%). In adults group, the most common cause was pharyngeal infection (19 patients, 22.2%). All of the 27 patients with associated disease comorbidity were adults and 17 were diabetes mellitus (DM). Streptococcus viridans was the most common pathogen in both children and adults groups. Eighty six (66.2%) underwent surgical drainage and complications were found in 31 patients (4 children, 27 adults). Deep neck infection in adults is easier to have multispace involvement and lead to complications and appears to be more serious than that in children. Understanding the different characteristics between the children and adults with deep neck infection may be helpful in accurate evaluation and proper management. © 2015 Wolters Kluwer Health, Inc. AD - Otorhinolaryngology Hospital, Otorhinolaryngology Institute, Sun Yat-sen University, Guangzhou, Guangdong Province, 510080, China Otolaryngological Department, Peking University Shenzhen Hospital, Shenzhen, Guangdon, China Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China Division of Otorhinolaryngology, First People's Hospital of Foshan, Foshan, China Division of Rheumatology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China AU - Yang, W. AU - Hu, L. AU - Wang, Z. AU - Nie, G. AU - Li, X. AU - Lin, D. AU - Luo, J. AU - Qin, H. AU - Wu, J. AU - Wen, W. AU - Lei, W. DB - Scopus DO - 10.1097/MD.0000000000000994 IS - 27 M3 - Article N1 - Cited By :20 Export Date: 10 November 2020 PY - 2015 SP - e994 ST - Deep neck infection: A review of 130 cases in southern China T2 - Medicine (United States) TI - Deep neck infection: A review of 130 cases in southern China UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84941043712&doi=10.1097%2fMD.0000000000000994&partnerID=40&md5=299ecfc17d0af723c99182dc434d17a6 VL - 94 ID - 1253 ER - TY - JOUR AB - Background: Case Report: Conclusions: key words: A fsh bone lodged in the oral cavity is in most cases removed simply; but, if it migrates, surgical intervention is necessary. We report a case of deep neck infection caused by the migration of a fsh bone which was not removed initially, as well as a case of a huge fsh bone migration found by chance along with complaints about mild symptoms. As there was no specifc fnding in simple X-ray examination and endoscopy, both of the 2 cases were diagnosed with neck CT. The fsh bones were removed with surgical exploration through lateral neck incision and the patients were discharged without any signifcant sequela. For patients swallowing a fsh bone, even though there is no abnormality in physical examination, simple X-ray and endoscopy, diagnosis should be made early through neck CT by considering the possibility of fsh bone migration. A surgical approach is needed to avoid any damage to the major structures. © The American Journal of Case Reports. AD - Departments of Otolaryngology - Head and Neck Surgery, College of Medicine, Chosun University, Gwangju, South Korea AU - Park, J. AU - Kim, B. AU - Jung, S. AU - Do, N. C7 - 882135 DB - Scopus DO - 10.12659/AJCR.882135 KW - Deep neck infections Fish bone Migrations M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2011 SP - 186-188 ST - Deep neck infection caused by fish bone migration and huge fish bone migration observed by chance: Two unusual cases of fish bone migration T2 - American Journal of Case Reports TI - Deep neck infection caused by fish bone migration and huge fish bone migration observed by chance: Two unusual cases of fish bone migration UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84855376950&doi=10.12659%2fAJCR.882135&partnerID=40&md5=a26764143fc766bbcd20fe13d73b164b VL - 12 ID - 1439 ER - TY - JOUR AB - PURPOSE: To compare the effectiveness of deep lamellar keratoplasty (DLK) with that of penetrating keratoplasty (PKP) in cases of corneal lesions not involving the endothelium. METHODS: Forty-eight eyes with leukomatous corneal opacity (n = 33), keratoconus with apical scarring (n = 6), granular corneal dystrophy (n = 5), lattice corneal dystrophy (n = 2), and multiple corneal foreign bodies (n = 2) in an age group varying from 16 to 53 years underwent DLK (n = 24) and PKP (n = 24) by utilizing B and (B+ and A) grade M-K preserved donor tissue, respectively. The patients were followed up closely, and the graft clarity, visual achievement, astigmatism and endothelial cell count were evaluated at repeated occasions up to 1 year. RESULTS: Astigmatism of <3 diopters (D) and > or = 5D was obtained in 19 eyes and one eye, respectively, after DLK at 6 months, whereas six eyes of the PKP group had astigmatism <3D, and 12 eyes had > or = 5D at the end of 6 months. The same at 1 year was observed in 20 and one eye in the DLK and eight and five eyes of the PKP group. Astigmatism of > or = 5D at the end of 6 months in both the groups showed highly significant changes (p < 0.001). Best corrected visual acuity of 6/18 or more was achieved in 18 and 12 eyes at 6 months after DLK and PKP, respectively, which were statistically highly significant (p < 0.001), whereas at 1 year, it was seen in 17 and 15 eyes of the DLK and PKP groups, respectively, which was nonsignificant. The mean endothelial cell count was 2,233.3+/-64.453 cells/mm2 and 2,219.6+/-102.48 cells/mm2 at 6 months and I year, respectively, after DLK, which was nonsignificant. The mean cell count of the donor eyes used for PKP was 2,191+/-52.164 cells/mm2, 1,902.8+/-70.346 cells/mm2 at 6 months, and 1,579.0+/-80.24 cells/mm2 at 1 year. All the values showed highly significant changes (p < 0.001). Further, the graft clarity of > or = 3+ was achieved in 20 and 18 eyes at 6 months postoperatively in the DLK and PKP groups, whereas the same was observed in 19 and 13 eyes of both the groups, respectively, at 1-year follow-up. CONCLUSION: DLK is a promising procedure and should be practiced more frequently for corneal pathology not involving the endothelium. AD - Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi. anitap@medinst.ernet.in AN - 10090362 AU - Panda, A. AU - Bageshwar, L. M. AU - Ray, M. AU - Singh, J. P. AU - Kumar, A. DA - Mar DO - 10.1097/00003226-199903000-00005 DP - NLM ET - 1999/03/25 IS - 2 KW - Adolescent Adult Cell Count Corneal Diseases/physiopathology/*surgery *Corneal Transplantation/methods Endothelium, Corneal/cytology Female Follow-Up Studies Graft Survival Humans *Keratoplasty, Penetrating/methods Male Middle Aged Postoperative Complications Visual Acuity LA - eng N1 - Panda, A Bageshwar, L M Ray, M Singh, J P Kumar, A Clinical Trial Comparative Study Journal Article United States Cornea. 1999 Mar;18(2):172-5. doi: 10.1097/00003226-199903000-00005. PY - 1999 SN - 0277-3740 (Print) 0277-3740 SP - 172-5 ST - Deep lamellar keratoplasty versus penetrating keratoplasty for corneal lesions T2 - Cornea TI - Deep lamellar keratoplasty versus penetrating keratoplasty for corneal lesions VL - 18 ID - 29 ER - TY - JOUR AB - Objectives: To determine TCR excision circle (TREC) levels, a marker of recent thymic emigrants, in the peripheral lymphocyte pool of rheumatoid factor-negative (RFØ) polyarticular juvenile idiopathic arthritis (JIA) children. Materials and methods: We studied TREC levels in peripheral blood mononuclear cells (PBMC) in 30 RFØ polyarticular JIA children with active disease and in 30 age- and gender-matched healthy controls. Signal-joint TREC concentration was determined by real-time quantitative-PCR as the number of TREC copies/μg PBMC DNA gauged by a standard curve with known number of TREC-containing plasmids. Results: TREC levels in PBMC were significantly lower in JIA (4.90±3.86 × 104 TRECs/μg DNA) as compared to controls (10.45±8.45 × 104 TRECs/μg DNA, p=0.001). There was an inverse correlation between age and TREC levels in healthy children (r=-0.438, p=0.016) but not in JIA. No clinical association was observed between TREC levels and disease activity and use of oral steroids and methotrexate. Conclusions: The finding of decreased PBMC TREC levels in RFØ polyarticular JIA children is consistent with a low proportion of recent thymus emigrants. This may interfere with the equilibrium between populations of polyclonal and naïve T cells versus oligoclonal memory auto-reactive T cells and, therefore, may hinder the maintenance of immune tolerance in this disease. © Copyright Clinical and Experimental Rheumatology 2010. AD - Rheumatology Division, Universidade Federal de São Paulo, São Paulo, Brazil Children's Institute, Division of Rheumatology, University of São Paulo, São Paulo, Brazil Pediatrics Department, Universidade Federal de São Paulo, São Paulo, Brazil AU - Horvath, D. AU - Kayser, C. AU - Silva, C. A. A. AU - Terreri, M. T. AU - Hilário, M. O. E. AU - Andrade, L. E. C. DB - Scopus IS - 3 KW - Juvenile idiopathic arthritis Recent thymus emigrants T lymphocyte Thymus TREC M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2010 SP - 348-353 ST - Decreased recent thymus emigrant number in rheumatoid factor-negative polyarticular juvenile idiopathic arthritis T2 - Clinical and Experimental Rheumatology TI - Decreased recent thymus emigrant number in rheumatoid factor-negative polyarticular juvenile idiopathic arthritis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77957004814&partnerID=40&md5=7daa7ad3a2e4d3ec7efdaf1d2fa3b90a VL - 28 ID - 1445 ER - TY - JOUR AB - BACKGROUND: Reducing granulomatous reaction for stent implantation is important for the treatment of tracheobronchomalacia because formation of granuloma leads to refractory complication causing further respiratory distress. The purpose of this study was to clarify granulomatous reaction of newly innovated coated stents compared to non-coated metal stents. METHODS: Materials and animal experiments were performed using the newly invented metallic stent (laser-cut stainless steel with a coating of polyurethane). In the materials experiment, the correlation between the holding force and deformity was tested by a compressor. In the animal examination, coated stents were orally implanted into the trachea in five rabbits, while non-coated stents were implanted in another five rabbits. After 3 weeks' observation, the inner diameter was measured by 3-D computed tomography, and the number of granulation tissues was counted by bronchofiberscope. Histological investigation followed in both groups. RESULTS: In the materials experiment, new stents demonstrated a holding force similar to stainless steel stents. In the animal experiment, no difference was found in the inner diameter of the coated and non-coated stent groups (5.70 ± 0.17 vs 5.60 ± 0.27, P = 0.07). However, the number of granulation tissues was higher in non-coated stents than in coated stents (1.60 ± 0.55 vs 0.40 ± 0.55, P < 0.01). Histological investigation showed direct attachment of metal to the tracheal wall around the non-coated stents where epithelial structure was destroyed, while tracheal epithelia were preserved in the group of coated stents. CONCLUSIONS: The new polyurethane-coated metallic stent maintains enough holding force, and reduces histobiological reaction to foreign bodies in this experiment. AD - Intensive Care Unit, Nagano Children's Hospital, Nagano, Japan. Department of Neonatology, Nagano Children's Hospital, Nagano, Japan. Department of Neonatology, Tokyo Women's Medical University Medical Centre East, Tokyo, Japan. Department of Pathology, Nagano Children's Hospital, Nagano, Japan. AN - 24750563 AU - Matsui, H. AU - Hiroma, T. AU - Hasegawa, H. AU - Ogiso, Y. DA - Dec DO - 10.1111/ped.12360 DP - NLM ET - 2014/04/23 IS - 6 KW - Animals Coated Materials, Biocompatible/adverse effects Equipment Design Granuloma, Foreign-Body/*etiology/*pathology/prevention & control Humans Materials Testing *Polyurethanes Rabbits Self Expandable Metallic Stents/*adverse effects Trachea/*pathology/*surgery airway collapse granulation tissue stent implantation tracheobronchomalacia LA - eng N1 - 1442-200x Matsui, Hikoro Hiroma, Takehiko Hasegawa, Hisaya Ogiso, Yoshifumi Journal Article Australia Pediatr Int. 2014 Dec;56(6):817-821. doi: 10.1111/ped.12360. Epub 2014 Oct 15. PY - 2014 SN - 1328-8067 SP - 817-821 ST - Decreased granulomatous reaction by polyurethane-coated stent in the trachea T2 - Pediatr Int TI - Decreased granulomatous reaction by polyurethane-coated stent in the trachea VL - 56 ID - 150 ER - TY - JOUR AB - There may be variability in the susceptibility of different individuals to osteolysis from wear debris, and it is not clear whether some individuals may have a genetic predisposition for a more marked osteolytic response. The purpose of this study in mice was to determine whether genetically determined obesity can alter the response to particulate debris. Polyethylene particles were implanted onto the calvaria of seven wild-type mice and seven obese mice (ob/ob). Calvaria from unimplanted wild-type and obese mice served as controls. Calvaria were harvested after 7 days, stained with toluidine blue and for tartrate-specific alkaline phosphatase, and analyzed by histomorphometry. The osteoclast number per mm total bone perimeter was 8.000±3.464 in wild-type animals with particles and 2.857±1.676 in ob/ob animals with particles (p=0.0002; Fisher's PLSD). Bone resorption was 1.895±0.713mm/ mm2 in wild-type animals with particles and 1.265±0.494mm/ mm2 in ob/ob animals with particles (p=0.0438; Fisher's PLSD). Particles induced a diminished osteolytic response in genetically determined obese mice, suggesting that obesity may have a protective role against particle-induced bone resorption - similar to obesity and osteoporosis. These important new findings may help to stimulate clinical studies which may define criteria to better identify patients at risk to develop particle-induced osteolysis. © 2004 Elsevier Ltd. All rights reserved. AD - Department of Orthopaedics, Mayo Clinic Rochester, 200 First Street SW, Rochester, MN 55905, United States Department of Orthopaedic Surgery, Orthopaedic University Hospital, University of Duisburg-Essen, Pattbergstrasse 1-3, 45239 Essen, Germany AU - Von Knoch, M. AU - Jewison, D. E. AU - Sibonga, J. D. AU - Turner, R. T. AU - Morrey, B. F. AU - Loer, F. AU - Berry, D. J. AU - Scully, S. P. DB - Scopus DO - 10.1016/j.biomaterials.2004.02.069 IS - 19 KW - Osteoclast Osteolysis Particulates Polyethylene Wear debris M3 - Article N1 - Cited By :22 Export Date: 10 November 2020 PY - 2004 SP - 4675-4681 ST - Decrease in particle-induced osteolysis in obese (ob/ob) mice T2 - Biomaterials TI - Decrease in particle-induced osteolysis in obese (ob/ob) mice UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-2342439389&doi=10.1016%2fj.biomaterials.2004.02.069&partnerID=40&md5=e3a6645204b167504b884ec437156db8 VL - 25 ID - 1626 ER - TY - JOUR AB - Objective: Unusual clinical course Background: Peritoneal loose bodies, also known as peritoneal mice, are rare findings and they present either with nonspe-cific symptoms or are found incidentally during exploration and autopsy. Usually, they have no clinical significance and require no specific treatment. We report a case of a giant peritoneal loose body found incidentally in the abdominal cavity of a patient who presented with abdominal pain and hematuria. Case Report: Our patient was a 58-year-old man who presented with abdominal pain and hematuria. Abdominal non-con-trast computed tomography (CT) and subsequent CT abdomen and pelvis with intravenous and oral rectal contrast were performed preoperatively, showing a well-circumscribed and calcified lesion of undetermined etiology in the abdominal cavity. The lesion was removed laparoscopically with no complications. Histopathologically, the lesion was reported as calcified tissue with fat necrosis, most likely an infarcted appendix epiploicae. Conclusions: Loose peritoneal bodies can present a challenging diagnostic problem to the surgeon, with confusing findings that can point towards malignancy. It often requires a number of investigations; however even with these investigations, operative exploration, either open or laparoscopic, can be the ultimate diagnostic and therapeutic modality, and the mobility of these calcified lesions may give a preoperative clue to the etiology. It is important to distinguish peritoneal loose bodies from neoplastic or metastatic lesions and to consider it in the differential diagnosis of a calcified mobile pelvic mass. Laparoscopic surgery is safe and effective in the retrieval of symptomatic peritoneal loose bodies. © Am J Case Rep, 2018. AD - Department of General Surgery, Hamad Medical Corporation, Doha, Qatar AU - Obaid, M. AU - Gehani, S. C7 - 908614 DB - Scopus DO - 10.12659/AJCR.908614 KW - Appendices epiploicae Boiled egg Hematuria Laparoscopic surgery Peritoneal loose body M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2018 SP - 854-857 ST - Deciding to remove or leave a peritoneal loose body: A case report and review of literature T2 - American Journal of Case Reports TI - Deciding to remove or leave a peritoneal loose body: A case report and review of literature UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054481969&doi=10.12659%2fAJCR.908614&partnerID=40&md5=bdeeb739263c04c63622453fd0fb4b5d VL - 19 ID - 1069 ER - TY - JOUR AB - For many years, blepharitis and dry eye disease have been thought to be two distinct diseases, and evaporative dry eye distinct from aqueous insufficiency. In this treatise, we propose a new way of looking at dry eye, both evaporative and insufficiency, as the natural sequelae of decades of chronic blepharitis. Dry eye is simply the late form and late manifestation of one disease, blepharitis. We suggest the use of a new term in describing this one chronic disease, namely dry eye blepharitis syndrome (DEBS). Bacteria colonize the lid margin within a structure known as a biofilm. The biofilm allows for population densities that initiate quorum-sensing gene activation. These newly activated gene products consist of inflammatory virulence factors, such as exotoxins, cytolytic toxins, and super-antigens, which are then present for the rest of the patient’s life. The biofilm never goes away; it only thickens with age, producing increasing quantities of bacterial virulence factors, and thus, increasing inflammation. These virulence factors are likely the culprits that first cause follicular inflammation, then meibomian gland dysfunction, aqueous insufficiency, and finally, after many decades, lid destruction. We suggest that there are four stages of DEBS which correlate with the clinical manifestations of folliculitis, meibomitis, lacrimalitis, and finally lid structure damage evidenced by entropion, ectropion, and floppy eyelid syndrome. When one fully understands the structure and location of the glands within the lid, it becomes easy to understand this staged disease process. The longer a gland can resist the relentless encroachment of the invading biofilm, the longer it can maintain normal function. The stages depend purely on anatomy and years of biofilm presence. Dry eye now becomes a very easy disease to understand. We feel that dry eye should be treated and prevented by early and routine biofilm removal through electromechanical lid margin debridement. © 2016 Rynerson and Perry. AD - BlephEx, LLC, Alvaton, KY, United States Department of Ophthalmology, Nassau University Medical Center, Hofstra University School of Medicine, East Meadow, NY, United States AU - Rynerson, J. M. AU - Perry, H. D. DB - Scopus DO - 10.2147/OPTH.S114674 KW - Aqueous insufficiency Biofilm Demodex Meibomian gland disease MGD Quorum-sensing gene activation M3 - Article N1 - Cited By :23 Export Date: 10 November 2020 PY - 2016 SP - 2455-2467 ST - DEBS - a unification theory for dry eye and blepharitis T2 - Clinical Ophthalmology TI - DEBS - a unification theory for dry eye and blepharitis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85010916992&doi=10.2147%2fOPTH.S114674&partnerID=40&md5=7181fdc51f33970f5f01f3546e5b2c62 VL - 10 ID - 1163 ER - TY - JOUR AB - Debridement of contaminated wounds is an essential component of uncomplicated wound healing. Efficient techniques should be capable of removing bacteria as well as foreign matter because of the well-known ability of foreign bodies to potentiate infection. We have compared the ability of current debridement techniques with the relatively new ultrasound debridement to clean wounds contaminated with bacteria and particulate matter. In part I, we prepared dorsal wounds on 15 Sprague-Dawley rats, and 20 mg of Montmorillonite clay soil fraction, a well-known infection-potentiating factor, was placed in each wound. Animals were randomly assigned to one of three treatment groups: ultrasound debridement, soaking, and irrigation. The amount of clay removed from each wound was measured. In part II, 48 Sprague- Dawley rats were given a standard wound and inoculated with a subinfective dose of Staphylococcus aureus bacteria and 10 mg of Montmorillonite clay particles. Each rat was randomly assigned to a debridement technique-soaking, scrubbing, high-pressure irrigation, and ultrasound-and was examined after 7 days for inflammatory responses. Results of part I demonstrated that ultrasound debridement and irrigation remove statistically equal amounts of clay (p < 0.05). In part II, we found that high-pressure irrigation and ultrasound debridement effectively treat contaminated wounds (gross infection, p < 0.05; wound induration, p < 0.0001; bacteria counts, p < 0.002). This study presents ultrasound debridement as effective treatment of contaminated wounds. AD - L.S. Nichter, 1140 W La Veta Ave, Orange, CA 92668-4202, United States AU - McDonald, W. S. AU - Nichter, L. S. DB - Embase Medline DO - 10.1097/00000637-199408000-00004 IS - 2 KW - animal experiment animal model animal tissue article bacterium contamination clay debridement foreign body human inflammation particulate matter priority journal rat surgical technique wound closure wound drainage wound healing wound infection wound irrigation LA - English M3 - Article N1 - L24262095 1994-09-05 PY - 1994 SN - 0148-7043 SP - 142-147 ST - Debridement of bacterial and particulate-contaminated wounds T2 - Annals of Plastic Surgery TI - Debridement of bacterial and particulate-contaminated wounds UR - https://www.embase.com/search/results?subaction=viewrecord&id=L24262095&from=export http://dx.doi.org/10.1097/00000637-199408000-00004 VL - 33 ID - 669 ER - TY - JOUR AB - Debridement is defined as the removal of nonviable material, foreign bodies, and poorly healing tissue from a wound. Although surgeons recognize the importance of debridement, few data have been generated in randomized trials to support its use. Debridement provides for removal of tissue with the highest bacterial count, reliable cultures, and identification of osteomyelitis. The most direct form of debridement is surgical excision. For patients who are poor candidates for surgical debridement or have limited access to a surgeon, other forms of debridement (including mechanical, autolytic, enzymatic, and biologic) can be used. Although operative debridement is best performed by those with surgical training, the other forms of debridement can be accomplished by other allied health care professionals. Debridement remains an important adjunct to good wound care, but questions of what type, how much, and how often it should be performed remain unresolved. AD - Department of Surgery, A1011 UPMC Presbyterian, 200 Lothrop Street, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA. steeddl@msx.upmc.edu AN - 15147995 AU - Steed, D. L. DA - May DO - 10.1016/s0002-9610(03)00307-6 DP - NLM ET - 2004/05/19 IS - 5a KW - Debridement/*methods Humans Wounds and Injuries/*therapy LA - eng N1 - Steed, David L Journal Article Review United States Am J Surg. 2004 May;187(5A):71S-74S. doi: 10.1016/S0002-9610(03)00307-6. PY - 2004 SN - 0002-9610 (Print) 0002-9610 SP - 71s-74s ST - Debridement T2 - Am J Surg TI - Debridement VL - 187 ID - 47 ER - TY - JOUR AB - Benefits of belatacept-based immunosuppressive regimens in human immunodeficiency virus (HIV)–positive renal transplant recipients include avoidance of drug interactions between calcineurin inhibitors and highly active antiretroviral agents and decreased likelihood or severity of nonimmune toxicities such as new-onset diabetes after transplant, hyperlipidemia and hypertension. We report a successful case of de novo belatacept at >18 mo from transplant in an HIV-positive black man aged 50 years who received his first transplant from a living related kidney donor. To our knowledge, this case is the first reported of belatacept use in an HIV-positive renal transplant recipient. © Copyright 2016 The American Society of Transplantation and the American Society of Transplant Surgeons AD - Department of Pharmacy Services, Yale-New Haven Hospital, New Haven, CT, United States Department of Surgery, Yale University, New Haven, CT, United States AU - Cohen, E. A. AU - Mulligan, D. AU - Kulkarni, S. AU - Tichy, E. M. DB - Scopus DO - 10.1111/ajt.13852 IS - 9 KW - clinical research/practice fusion proteins and monoclonal antibodies: belatacept immunosuppressant immunosuppression/immune modulation infection and infectious agents kidney transplantation/nephrology viral: human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2016 SP - 2753-2757 ST - De Novo Belatacept in a Human Immunodeficiency Virus–Positive Kidney Transplant Recipient T2 - American Journal of Transplantation TI - De Novo Belatacept in a Human Immunodeficiency Virus–Positive Kidney Transplant Recipient UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84984600724&doi=10.1111%2fajt.13852&partnerID=40&md5=0ec275329fc1cbee7a59bcbe9b924647 VL - 16 ID - 1173 ER - TY - JOUR AB - LEARNING OBJECTIVE 1: Recognize that a positive blood culture of coagulase-negative staphylococci may not always be a contaminant LEARNING OBJECTIVE 2: Recognize the clinical signs and symptoms of endocarditis caused by Staphylococcus lugdunensis CASE: A 70 year-old Japanese woman with a past medical history of cerebral palsy presents with 1-month's history of decrease in appetite and weight. She also reports generalized body weakness while denying fevers, chills, chest pain, palpitations, shortness of breath, cough, urinary changes, and rashes. Her significant physical findings include temperature of 35.3°Celsius, blood pressure of 85/48 mmHg, heart rate of 87 beats/minute, respiratory rate of 30 breaths/minute, and oxygen saturation of 100% on 10 liters of oxygen. She is lethargic and disoriented to time, place, and person; she also has poor oral hygiene with saprodontia. She has no heart murmurs, costovertebral angle tenderness, back pain, or skin lesions. The remainder of her examination is unremarkable. In addition, significant laboratory findings consist of white blood cell count (WBC) of 23,240/μL (4% bands, 93% segmented neutrophils), hemoglobin of 7.9 g/dL, platelets of 65,000/ μL, blood urea nitrogen of 68 g/dL, and creatinine of 1.2 mg/dL. Urinalysis shows 2+ protein , 3+ heme, >100 red blood cells/high power field (HPF), >100 WBC /HPF, and 3+ bacteria. A computed tomographic scan of the chest, abdomen, and pelvis reveals bilateral pleural effusions and bladder masses with hydronephrosis. Given her septic shock from presumed urinary tract infection, she has been empirically started on meropenem. Her encephalopathy, however, does not improve, and she even develops right-sided hemiparesis; a magnetic resonance imaging of the brain shows multiple areas of embolic cerebral infarcts. She also develops a renal infarction, splenic abscess, and iliopsoas abscess for which their drainage shows no bacteria. Her antimicrobial regimen has thus been changed to ceftriaxone and vancomycin for suspicion of infectious endocarditis; a transesophageal echocardiogram shows a vegetation on the mitral valve with regurgitation. During this time, all 3 sets of blood cultures have grown coagulase-negative staphylococcus (CNS), Staphylococcus lugdunensis in particular. Despite aggressive medicalmanagement and scheduledmitral valve replacement, the patient dies after 18 days of admission. DISCUSSION: As part of the normal skin flora, CNS has often been identified as a blood culture contaminant but has become increasingly recognized as a clinically significant pathogen even in cases of native valve endocarditis (NVE). In particular, S. lugdunensis can cause severe infections frequently attributable to Staphylococcus aureus. While both of these species produce a bound coagulase, S. lugdunensis, however, does not produce a free coagulase. Patients with immunosuppression and foreign bodies such as prosthetic devices and intravascular catheters are at a higher risk of infection with S. lugdunensis. The clinical presentation of NVE caused by CNS is indistinguishable from Streptococcus viridans and includes fever, generalized weakness, weight loss, and anorexia; about 25-33% of patients exhibit Osler's nodes, Janeway lesions, and splinter hemorrhages. While this case may have clinical signs and symptoms similar to S. viridans, one must not discount blood culture results initially showing CNS as just a blood culture contaminant. AD - D. Morikawa, Medical Center, Sapporo, Japan AU - Morikawa, D. AU - Keijinkai, T. DB - Embase KW - coagulase oxygen vancomycin creatinine synapsin II heme meropenem antiinfective agent ceftriaxone hemoglobin sheep clothing case report endocarditis Staphylococcus lugdunensis society internal medicine wolf human blood culture patient physical disease by body function infection coagulase negative Staphylococcus fever bacterium weakness central nervous system thorax pain skin defect weight heart murmur examination laboratory leukocyte count appetite oxygen saturation cerebral palsy breathing rate heart rate computer assisted tomography blood pressure pleura effusion urinary tract infection mouth hygiene brain backache kidney infarction spleen abscess neutrophil blood medical history female urinalysis temperature risk prosthesis body weight loss thorax abdomen pelvis bladder hydronephrosis septic shock rash brain disease hemiparesis nuclear magnetic resonance imaging urea nitrogen blood level brain infarction thrombocyte coughing abscess Staphylococcus aureus bacterial endocarditis echocardiography dyspnea pathogenesis skin flora heart valve replacement mitral valve species vegetation immunosuppressive treatment foreign body intravascular catheter alpha hemolytic Streptococcus anorexia bleeding heart palpitation Japanese (people) LA - English M3 - Conference Abstract N1 - L71297455 2014-01-24 PY - 2012 SN - 0884-8734 SP - S508 ST - “A dangerous wolf in sheep's clothing: ” A case report of destructive endocarditis caused by staphylococcus lugdunensis T2 - Journal of General Internal Medicine TI - “A dangerous wolf in sheep's clothing: ” A case report of destructive endocarditis caused by staphylococcus lugdunensis UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71297455&from=export VL - 27 ID - 512 ER - TY - JOUR AB - Eight years after a penetrating steel foreign body had been removed from the eye of a 26-year-old male a glaucoma developed. A cataract and a large iris cyst was discovered. Following intracapsular lens extraction and secondary removal of the iris cyst by keratome-scissors incision, the eye remained comfortable with unconnected vision of finger-counting at three feet. AD - Memphis Society of Ophthalmology and Otolaryngology AU - Lewis, P. M. DB - Embase Classic IS - 3 KW - steel cataract cyst extraction eye foreign body glaucoma incision iris iris atrophy lens male LA - English M3 - Article N1 - L280401520 1947-12-01 PY - 1947 SN - 0002-9394 SP - 334 ST - Cyst of the iris T2 - American Journal of Ophthalmology TI - Cyst of the iris UR - https://www.embase.com/search/results?subaction=viewrecord&id=L280401520&from=export VL - 30 ID - 697 ER - TY - JOUR AB - In order to understand events and mechanisms present in the pathophysiology of tilapia's chronic inflammation and based on the immunomodulatory activity attributed to cyclophosphamide which is widely used to suppress immune responses in human medicine, the present study investigated the effects of cyclophosphamide (CYP) treatment on the modulation of foreign body inflammatory reaction in Nile tilapia (Oreochromis niloticus) with round glass coverslip implanted in the subcutaneous tissue (9 mm of diameter). Forty tilapia (151 ± 10,2 g) were randomly distributed in 5 aquariums (n = 8) with a capacity of 250 L of water each, to compose two treatments (sampled 3 and 6 days post-implantation): implanted/untreated (control) and implanted/treated with 200 mg of CYP kg(-1) of b.w., through i.p. route. A fifth group (n = 8) was sampled without any stimulus (naive) to obtain reference values. CYP-treated tilapia showed decrease in macrophage accumulation, giant cell formation and Langhans cells on the glass coverslip when compared to control fish. The treatment with CYP resulted in decrease of leukocyte and thrombocyte counts. Decrease in alpha-2-macroglobulin, ceruloplasmin, albumin and transferrin levels, as well as increase in haptoglobin, complement C3 and apolipoprotein A1 were observed in tilapias during foreign body inflammation. Blood levels of complement C3, alpha-2-macroglobulin, ceruloplasmin and transferrin were modulated by treatment with CYP. Therefore, the treatment with 200 mg of CYP kg(-1) of b.w. in tilapia resulted in an anti-inflammatory effect by suppressing the dynamics between leukocytes in the bloodstream and macrophage accumulation with giant cell formation in the inflamed focus, as well as by modulating APPs during foreign body reaction. AD - Department of Pharmacology, Institute of Biomedical Science, University of São Paulo (USP), São Paulo, SP, Brazil. Department of Preventive Veterinary Medicine, São Paulo State University (UNESP), Jaboticabal, SP, Brazil. Veterinary College, Federal University of Rondonia (UNIR), Rolim de Moura, RO, Brazil. Department of Graduate Program in Health Sciences, Federal University of Roraima (UFRR), Boa Vista, RR, Brazil. Laboratório de Bioquímica de Peptídeos, UNIFESP, São José dos Campos, SP, Brazil. Department of Preventive Veterinary Medicine, São Paulo State University (UNESP), Jaboticabal, SP, Brazil; Laboratory of Animal Pharmacology and Toxicology, Brasil University, Descalvado, SP, Brazil. Electronic address: maabelo@hotmail.com. AN - 33039531 AU - Charlie-Silva, I. AU - Conde, G. AU - Mendonça Gomes, J. M. AU - Johnny da Rosa Prado, E. AU - Fernandes, D. C. AU - Cristina de Moraes, A. AU - Eto, S. F. AU - Conceição, K. AU - Antonio de Andrade Belo, M. DA - Oct 9 DO - 10.1016/j.fsi.2020.09.039 DP - NLM ET - 2020/10/12 IS - Pt A KW - Acute phase proteins Alkylating agents Chronic inflammation Cichlids Giant cells Innate immunity Langhans cells Macrophages LA - eng N1 - 1095-9947 Charlie-Silva, Ives Conde, Gabriel Mendonça Gomes, Juliana Moreira Johnny da Rosa Prado, Ed Fernandes, Dayanne Carla Cristina de Moraes, Alessandra Eto, Silas Fernandes Conceição, Katia Antonio de Andrade Belo, Marco Journal Article England Fish Shellfish Immunol. 2020 Oct 9;107(Pt A):230-237. doi: 10.1016/j.fsi.2020.09.039. PY - 2020 SN - 1050-4648 SP - 230-237 ST - Cyclophosphamide modulated the foreign body inflammatory reaction in tilapia (Oreochromis niloticus) T2 - Fish Shellfish Immunol TI - Cyclophosphamide modulated the foreign body inflammatory reaction in tilapia (Oreochromis niloticus) VL - 107 ID - 265 ER - TY - JOUR AB - A 66-year-old woman presented with an asymptomatic yellow nodule on her left cheek that rapidly progressed to encroach on her eyelid. She had undergone a biopsy 5 months earlier from a similar infraorbital lesion, which suggested a diagnosis of necrobiotic xanthogranuloma (NXG). She required multiple re-excisions, but was systemically well with no evidence of underlying malignancy at the time. On examination, there was a xanthomatous indurated plaque extending from her left zygoma up to her medial canthus with associated superficial telangiectasia. Her blood results and paraprotein screen were initially unremarkable apart from a persistently raised alkaline phosphatase. Her full blood count initially had been normal, but following her recurrence she developed mild neutropenia. She underwent further biopsies from the left side of her nose, zygoma, medial canthus and cheek. All four lesions demonstrated a lymphohistiocytic cellular infiltrate, multinucleated giant cells of foreign body and Touton types, and areas of fibrinoid necrosis containing cholesterol crystals consistent with NXG. There was an infiltrate of mature lymphocytes, morphologically consistent with chronic lymphocytic leukaemia (CLL). Immunohistochemistry confirmed CD20-positive B cells, with coexpression of CD23 and CD5. Bone marrow trephine biopsy confirmed classical CLL. At first her haemato-oncologist was reluctant to treat her CLL as it was not severe enough, but chemotherapy was commenced because of the aggressive nature of the NXB. There was an excellent response following completion of four cycles of chlorambucil and obinutuzumab, an anti-CD20 monoclonal antibody, with complete remission of the NXG, which has remained in remission after 12 months with no need for further chemotherapy. NXG is a rare non-Langerhans cell histiocytosis involving skin and extracutaneous tissues, with approximately 100 reported cases. Cutaneous manifestations are progressive and destructive, with infiltrating plaques predominantly affecting the periorbital region. NXG is often associated with paraproteinaemia; 80% of patients have a serum monoclonal gammopathy, 10% develop multiple myeloma and it is infrequently linked to CLL. The pathogenesis of NXG remains unclear. Data on therapeutic options are limited with currently no consensus on first-line treatment. Several treatments have been described with variable results, including topical or systemic corticosteroids, thalidomide, intravenous immunoglobulin, alkylating agents, rituximab, melphalan, infliximab, interferon-alpha, laser therapy, radiotherapy, surgery, psoralen-ultraviolet A and plasmapheresis. A systematic review suggested that several case reports have demonstrated good response with chlorambucil, as seen in our case, which has prompted the authors to design an algorithm with chlorambucil as the first-line treatment. There are no reported cases on the effect of obinutuzumab on NXG. AD - L. Asfour, Royal Marsden NHS Foundation Trust, London, United Kingdom AU - Asfour, L. AU - Mortimer, P. DB - Embase DO - 10.1111/bjd.15525 KW - alkaline phosphatase alpha interferon CD20 antigen CD23 antigen CD5 antigen chlorambucil cholesterol corticosteroid endogenous compound human immunoglobulin infliximab melphalan obinutuzumab paraprotein psoralen rituximab thalidomide unclassified drug aged blood cell count bone marrow biopsy cell infiltration cheek chemotherapy chronic lymphatic leukemia consensus diagnosis drug combination excision eyelid female gene expression giant cell histiocytosis human human tissue immunohistochemistry leukemia remission low level laser therapy monoclonal immunoglobulinemia multiple myeloma necrobiotic xanthogranuloma necrosis neutropenia nose oncologist plasmapheresis radiotherapy relapse skin surgery systematic review telangiectasia topical drug administration ultraviolet A radiation xanthomatosis zygoma LA - English M3 - Conference Abstract N1 - L617313372 2017-07-18 PY - 2017 SN - 1365-2133 SP - 152-153 ST - Cutaneous necrobiotic xanthogranuloma due to B-cell chronic lymphocytic leukaemia with full remission from treatment with chlorambucil and obinutuzumab T2 - British Journal of Dermatology TI - Cutaneous necrobiotic xanthogranuloma due to B-cell chronic lymphocytic leukaemia with full remission from treatment with chlorambucil and obinutuzumab UR - https://www.embase.com/search/results?subaction=viewrecord&id=L617313372&from=export http://dx.doi.org/10.1111/bjd.15525 VL - 177 ID - 369 ER - TY - JOUR AB - A 55-year-old man was admitted to our hospital with infectious nodules on the right medial orbital area which he had noticed since about a month before. Laboratory tests showed mild liver dysfunction but WBC count, CRP, angiotensin converting enzyme (ACE) and CD4/8 ratio were all within normal limits. Serologic titers for anti-nuclear autoantibodies were negative. The tuberculin reaction was negative, and neither Mycobacterium tuberculosis nor other atypical Mycobacterium sp. were detected from the lesional tissue biopsy specimen. The magnetic resonance imaging suggested an existence of a foreign material in the right orbita. So he was underwent an operation and we found a wood piece which was about 5mm in diameter and about 35mm long. We propose that we should also pay attention to an existence of a foreign body if inflammatory granulomatous lesions are hardly healed by conservative medical treatments. © 2001, Meeting of Osaka Dermatological Association. All rights reserved. AD - Department of Dermatology, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan Furukawa Dermatology Office, 1-1-6 Nagaremachi, Hirano-ku, Osaka 547-0032, Japan Tanii Dermatology Office, 2-4-5 Tokui-cho, Chuo-ku, Osaka 540-0025, Japan AU - Ueoku, S. AU - Maekawa, N. AU - Ishii, M. AU - Furukawa, M. AU - Tanii, T. DB - Scopus DO - 10.11340/skinresearch1959.43.163 IS - 3 KW - foreign body implantation dermatosis wood piece M3 - Article N1 - Export Date: 10 November 2020 PY - 2001 SP - 163-166 ST - Cutaneous Inflammatory Reaction to a Wood Piece; A Peculiar Case of Implantation Dermatoses T2 - Skin Research TI - Cutaneous Inflammatory Reaction to a Wood Piece; A Peculiar Case of Implantation Dermatoses UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85024463113&doi=10.11340%2fskinresearch1959.43.163&partnerID=40&md5=72aeeeb626e2edbfdcb8e3985b21fe97 VL - 43 ID - 1673 ER - TY - JOUR AB - BACKGROUND: Marking of surgical instruments is essential to ensure their proper identification after sterile processing. The National Quality Forum defines unintentionally retained foreign objects in a surgical patient as a serious reportable event also called "never event." PRESENTATION OF THE HYPOTHESIS: We hypothesize that established practices of surgical instrument identification using unkempt tape labels and plastic tags may expose patients to "never events" from retained disintegrating labels. TESTING OF THE HYPOTHESIS: We demonstrate the near miss of a "never event" during a surgical case in which the breakage of an instrument label remained initially unwitnessed. A fragment of the plastic label was accidentally found in the wound upon closing. Further clinical testing of the occurrence of this "never event" appears not feasible. As the name implies a patient should never be exposed to the risk of fragmenting labels. IMPLICATION OF THE HYPOTHESIS: Current practice does not mandate verifying intact instrument markers as part of the instrument count. The clinical confirmation of our hypothesis mandates a change in perioperative practice: Mechanical labels need to undergo routine inspection and maintenance. The perioperative count must not only verify the quantity of surgical instruments but also the intactness of labels to ensure that no part of an instrument is left behind. Proactive maintenance of taped and dipped labels should be performed routinely. The implementation of newer labeling technologies - such as laser engraved codes - appears to eliminate risks seen in traditional mechanical labels.This article reviews current instrument marking technologies, highlights shortcomings and recommends safe instrument handling and marking practices implementing newer available technologies. AD - Department of Orthopaedic Surgery, Denver Health Medical Center, 777 Bannock Street, Denver, CO 80204, USA. Kyros.ipaktchi@dhha.org. AN - 24079615 AU - Ipaktchi, K. AU - Kolnik, A. AU - Messina, M. AU - Banegas, R. AU - Livermore, M. AU - Price, C. C2 - PMC3849939 DA - Sep 30 DO - 10.1186/1754-9493-7-31 DP - NLM ET - 2013/10/02 IS - 1 LA - eng N1 - 1754-9493 Ipaktchi, Kyros Kolnik, Adam Messina, Michael Banegas, Rodrigo Livermore, Meryl Price, Connie Journal Article Patient Saf Surg. 2013 Sep 30;7(1):31. doi: 10.1186/1754-9493-7-31. PY - 2013 SN - 1754-9493 (Print) 1754-9493 SP - 31 ST - Current surgical instrument labeling techniques may increase the risk of unintentionally retained foreign objects: a hypothesis T2 - Patient Saf Surg TI - Current surgical instrument labeling techniques may increase the risk of unintentionally retained foreign objects: a hypothesis VL - 7 ID - 143 ER - TY - JOUR AB - Deep sternal wound infection (DSWI), also known as mediastinitis, is a serious and potentially fatal condition. The diagnosis and treatment of DSWI are challenging. In this current narrative review, the epidemiology, risk factors, diagnosis, and surgical and antimicrobial management of DSWI are discussed. Ideally, the management of DSWI requires early and sufficient surgical debridement and appropriate antibiotic therapy. When foreign material is present, biofilm-active antibiotic therapy is also needed. Because DSWI is often complex, the management requires the involvement of a multidisciplinary team consisting of cardiothoracic surgeons, plastic surgeons, intensivists, infectious disease specialists, and clinical microbiologists. © 2018 Yusuf et al. AD - Department of Medical Microbiology, Antwerp University Hospital (UZA), University of Antwerp, Antwerp, Belgium Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore Charité Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Center for Musculoskeletal Surgery (CMSC), Berlin, Germany AU - Yusuf, E. AU - Chan, M. AU - Renz, N. AU - Trampuz, A. DB - Scopus DO - 10.2147/IDR.S130172 KW - Antibiotic Deep sternal wound infection Diagnosis Surgical treatment M3 - Review N1 - Cited By :12 Export Date: 10 November 2020 PY - 2018 SP - 961-968 ST - Current perspectives on diagnosis and management of sternal wound infections T2 - Infection and Drug Resistance TI - Current perspectives on diagnosis and management of sternal wound infections UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85057626593&doi=10.2147%2fIDR.S130172&partnerID=40&md5=4c7ef3f04b1cb15f1c0f20e439625add VL - 11 ID - 1097 ER - TY - JOUR AB - Introduction: The aim of this study was to evaluate the current indications for and clinical factors influencing the use of transnasal esophagoscopy (TNE). Methods: An online survey was sent to American Broncho-Esophagological Association members, including questions on demographics, indications, and factors influencing the use of TNE. Results: Sixty of 251 members (24%) completed the survey. Ninety-three percent of respondents reported academic practices, while 98% practice in medium to large urban settings. Thirty-five (58%) completed laryngology fellowships. Mean monthly TNE procedure count was 7.15 (range, <1-35). The most common indications were dysphagia (82%), biopsy (50%), and laryngopharyngeal reflux (47%). Chronic cough, head and neck cancer screening, gastroesophageal reflux (GER), and tracheoesophageal puncture were also commonly reported indications (44% each). For laryngopharyngeal reflux and GER, most respondents perform TNE for recalcitrant disease following a medical trial of at least 3 months. Long-standing GER symptoms, documentation of GER on pH and impedance testing, and abnormal findings on previous esophagoscopy lead to greater TNE use. Specific dysphagia indications included abnormal esophagographic findings (70%), history or examination localizing to the esophagus (60%), solid dysphagia only (53%), and solid and/or liquid dysphagia (40%). The primary sites most likely to prompt TNE use for head and neck cancer surveillance were the esophagus (92.3%) and hypopharynx (84.6%). Balloon dilation was the most common indication for which respondents do not currently perform TNE but would like to (n = 8). Conclusions: TNE indications have not been well established. According to respondents from the American Broncho-Esophagological Association, TNE is most commonly used for dysphagia and laryngopharyngeal reflux and slightly less so for GER and head and neck cancer screening and surveillance. Several clinical indicators were identified that influence the decision to perform TNE. © The Author(s) 2018. AD - Department of Otolaryngology–Head and Neck Surgery, Indiana University, Indianapolis, IN, United States Department of Speech, Language, and Hearing Sciences, Purdue University, Lafayette, IN, United States Department of Speech and Hearing Sciences, Indiana University, Bloomington, IN, United States The Voice Clinic of Indiana, Carmel, IN, United States AU - Best, A. R. AU - Halum, S. L. AU - Parker, N. P. DB - Scopus DO - 10.1177/0003489418800840 IS - 12 KW - dysphagia esophagoscopy globus office-based reflux transnasal M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2018 SP - 926-930 ST - Current Indications for Transnasal Esophagoscopy: An American Broncho-Esophagological Association Survey T2 - Annals of Otology, Rhinology and Laryngology TI - Current Indications for Transnasal Esophagoscopy: An American Broncho-Esophagological Association Survey UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85055914229&doi=10.1177%2f0003489418800840&partnerID=40&md5=6d36579187e32f55df225f69b40fe149 VL - 127 ID - 1053 ER - TY - JOUR AB - Significant changes have taken place in the epidemiology, microbiology and antibiotic therapy of bone and joint infections. Gram-negative bacilli have become an increasingly common cause, particularly in immunocompromised patients; anaerobes have been implicated in osteomyelitis associated with metallic foreign bodies; and there is increasing use of oral antibiotic regimens following an initial period of parenteral treatment. Gram-negative bacilli and anaerobes are found in polymicrobial non-haematogenous osteomyelitis (e.g. post-traumatic, post-surgical), but Staphylococcus aureus remains the most common cause of acute haematogenous osteomyelitis, with streptococci and Haemophilus influenzae responsible for most of the remainder. A precise microbiological diagnosis is essential. Diagnosis is based on Gram stain and culture of bone biopsies or aspirated pus, or on blood cultures. Specimens should be obtained before starting therapy. Any suspected primary foci of infection should be cultured. Parenteral antibiotics are given as soon as specimens are obtained, and continued for at least 3 weeks. The common causative organisms in septic arthritis are the same as in osteomyelitis, with the addition of Neisseria gonorrhoeae in young, sexually active adults. As in osteomyelitis, a precise microbiological diagnosis is of paramount importance, ideally by joint aspiration for cell count, Gram stain, biochemical analysis and culture, or by blood cultures. Optimum therapy is with antibiotics, repeated therapeutic aspirations, and resting the joint. Parenteral antibiotics should be started as soon as specimens are obtained and continued for 4 to 6 weeks. Gonococcal arthritis, however, can be treated successfully with 1 week of antibiotics. When treatment of either osteomyelitis or septic arthritis is continued with oral antibiotics, serum antibiotic concentrations or serum bactericidal levels are mandatory to ensure adequate absorption. AN - 3792229 AU - Dickie, A. S. DA - Nov DO - 10.2165/00003495-198632050-00004 DP - NLM ET - 1986/11/01 IS - 5 KW - Administration, Oral Anti-Bacterial Agents/*therapeutic use Arthritis, Infectious/diagnosis/*drug therapy/etiology/microbiology Humans Osteomyelitis/diagnosis/*drug therapy/etiology/microbiology LA - eng N1 - Dickie, A S Journal Article New Zealand Drugs. 1986 Nov;32(5):458-75. doi: 10.2165/00003495-198632050-00004. PY - 1986 SN - 0012-6667 (Print) 0012-6667 SP - 458-75 ST - Current concepts in the management of infections in bones and joints T2 - Drugs TI - Current concepts in the management of infections in bones and joints VL - 32 ID - 14 ER - TY - JOUR AB - INTRODUCTION: Sharp objects impacted in the esophagus require prompt endoscopic removal. Removal of sharp foreign bodies can be technically challenging and care should be taken to avoid inducing esophageal trauma during retrieval. CASE DESCRIPTION/METHODS: A 69-year-old female presented with sudden onset dysphagia and sharp chest pain for 1 day. While eating cake one day prior to arrival, she reported sudden, sharp, central chest pain followed by a sensation of food being stuck in her esophagus. Her physical examination was unremarkable with no abdominal tenderness. Her laboratory tests revealed normal complete blood count and chemistry. Chest x-ray revealed no acute abnormality. Upper endoscopy showed a sharp star-shaped foreign body (FB) approximately 2 cm in diameter (Figure 1). The FB was lodged in the distal esophagus, causing mucosal trauma. Due to the large size of the FB, insertion of an overtube was not considered to facilitate removal. An attempt was first made to extract the FB with rat-tooth forceps, but it could not be retrieved through the upper esophageal sphincter. Mucosal trauma was seen in the mid and proximal esophagus following this attempt. The FB was then advanced to the gastric antrum using a Roth net. Attempts to break the FB using argon plasma coagulation (APC) and a snare were unsuccessful due to the rigid nature of the FB. Subsequently, a 2T dual channel therapeutic gastroscope was inserted, and a Dormia stone retrieval basket was used to grasp the foreign body. Using the crushing power of the basket, the FB was successfully crushed and pulled inside the large therapeutic channel of the scope. The scope was withdrawn without additional mucosal trauma. The FB consisted of a star-shaped cake decoration with sharp edges (Figure 2). Following the procedure, the patient reported immediate improvement in her chest pain. DISCUSSION: This is a unique case wherein after the failure of conventional foreign body extraction devices, a Dormia stone retrieval basket was used to crush the object within the stomach allowing for safe retrieval. Gastroenterologists should consider this approach when retrieving irregularly-shaped, sharp, but pliable FBs. For the general public, care should be taken when eating food with non-edible decorations and toppers to avoid inadvertently swallowing or aspirating these objects. (Figure Presented). AD - S. Kilakkathi, Emory University, School of Medicine, Atlanta, GA, United States AU - Kilakkathi, S. AU - Shah, R. AU - Mulki, R. AU - Qayed, E. DB - Embase DO - 10.14309/01.ajg.0000597132.38406.65 KW - abdominal tenderness aged animal experiment argon plasma coagulation blood cell count conference abstract dysphagia eating endoscopy esophagus foreign body female forceps gastroenterologist gastroscope human laboratory test nonhuman physical examination rat sensation stomach antrum stone retrieval basket thorax pain thorax radiography tooth treatment failure upper esophagus sphincter LA - English M3 - Conference Abstract N1 - L630838820 2020-02-12 PY - 2019 SN - 1572-0241 SP - S1063 ST - Crushing the star: Esophageal foreign body extraction using dormia basket T2 - American Journal of Gastroenterology TI - Crushing the star: Esophageal foreign body extraction using dormia basket UR - https://www.embase.com/search/results?subaction=viewrecord&id=L630838820&from=export http://dx.doi.org/10.14309/01.ajg.0000597132.38406.65 VL - 114 ID - 304 ER - TY - JOUR AB - The authors present a patient with a presumed diagnosis of Crohn's disease for 6 years turning out to be an unusual inflammatory mass caused by ileal perforation due to a foreign body. When surgical intervention became necessary for admissions with recurrent obstruction, laparoscopy revealed an inflammatory mass in the terminal ileum, exposing two pieces of plastic bearing the word 'Heinz'. Resection of the inflammatory mass led to the complete resolution of symptoms. Histology from the operative specimen showed no features of Crohn's disease. There were no granulomas and no fissuring ulcers. This case highlights that an inflammatory mass in the small intestine caused by the perforation of ingested foreign body can mimic Crohn's disease. To our knowledge, this is the first report of a synthetic plastic packaging causing ileo-caecal junctional perforation mimicking Crohn's disease. Copyright 2013 BMJ Publishing Group. All rights reserved. AD - General Surgery Department, Heatherwood and Wexham Park Hospital, Slough, United Kingdom AU - Visagan, R. AU - Grossman, R. AU - Dimitriadis, P. A. AU - Desai, A. DB - Scopus DO - 10.1136/bcr-2013-009603 M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2013 ST - 'Crohn'z meanz Heinz': Foreign body inflammatory mass mimicking Crohn's disease T2 - BMJ Case Reports TI - 'Crohn'z meanz Heinz': Foreign body inflammatory mass mimicking Crohn's disease UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879849561&doi=10.1136%2fbcr-2013-009603&partnerID=40&md5=7e8590e7f6ce84720447eb3a39fddbe4 ID - 1316 ER - TY - JOUR AB - Purpose: A 48-year-old man with ulcerative pancolitis diagnosed 6 years prior to admission was transferred to our institution with sharp non-radiating right lower quadrant pain. There was no history of fever, chills, nausea, vomiting, or diarrhea. The patient had been in remission on azathioprine 100 mg and mesalamine 2,000 mg per day after a single course of prednisione at the time of diagnosis. Physical exam was significant for tenderness to palpation in the right lower quadrant. The white blood cell count and hemoglobin were normal. A computed tomography scan of the abdomen with oral and intravenous contrast demonstrated an inflammatory process at the cecal apex with associated 5 cm phlegmon. The appendix was not visualized. Mild lymphadenopathy was present. The small bowel and colon appeared normal with the exception of possible narrowing and hypertrophy of the terminal ileum at the ileocecal valve. The patient was diagnosed with appendicitis and managed conservatively with intravenous antibiotics and bowel rest. His diet was slowly advanced and he was discharged home on a 2-week course of ciprofloxacin 500 mg twice daily and metronidazole 500 mg three times daily. Subsequent colonoscopy revealed a 4 cm non-obstructing mass in the cecum. The colon distal to the cecum was normal without mucosal breaks or friability. Biopsies of the cecal mass revealed normal colonic mucosa with mild inflammation and mild architectural change. Diagnostic laparoscopy demonstrated an abnormal appearing inflamed appendix. A laparoscopic appendectomy was performed. The surgical specimen measured 5.6 x 4.5 x 3.0 cm and contained no masses. Architectural distortion, transmural acute and chronic inflammation, and epithelioid cell aggregates with giant cell reaction were present. The patient's diagnosis was changed to Crohn's colitis with appendiceal involvement. Crohn's disease (CD) involves the appendix in up to 50% of patients with colonic CD. CD isolated to the appendix is rare and has been described in fewer than 160 cases. We believe that this is the first report of a patient diagnosed with UC to have his diagnosis changed due to symptomatic appendiceal CD. Symptoms of granulomatous disease of the appendix are similar to acute appendicitis and include fever, right lower quadrant pain, nausea, and anorexia. Other causes of appendiceal granulomatous disease include infection (e.g., Yersinia, Mycobacterium tuberculosis, Campylobacter), foreign body reaction, appendiceal or cecal diverticulitis, chronic beryllium poisoning, and sarcoidosis. Our patient did well post-operatively. Azathioprine and mesalamine were continued. AD - L. McLean, University of Maryland, School of Medicine, Baltimore, United States AU - McLean, L. AU - Chun, J. AU - Cross, R. DB - Embase DO - 10.1038/ajg.2013.267 KW - azathioprine mesalazine antibiotic agent ciprofloxacin hemoglobin metronidazole appendicitis college gastroenterology Crohn disease human patient diagnosis inflammation nausea pain fever cecum granulomatosis diet intestine ileocecal valve berylliosis ileum hypertrophy lymphadenopathy Mycobacterium tuberculosis phlegmon computer assisted tomography acute appendicitis anorexia abdomen Campylobacter diverticulitis small intestine remission colitis leukocyte count diarrhea pancolitis palpation appendectomy laparoscopy colon mucosa biopsy chronic inflammation epithelioid cell cell aggregation giant cell vomiting colonoscopy infection Yersinia foreign body reaction sarcoidosis male LA - English M3 - Conference Abstract N1 - L71221735 2013-11-15 PY - 2013 SN - 0002-9270 SP - S426 ST - Crohn's disease: An uncommon cause of appendicitis T2 - American Journal of Gastroenterology TI - Crohn's disease: An uncommon cause of appendicitis UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71221735&from=export http://dx.doi.org/10.1038/ajg.2013.267 VL - 108 ID - 474 ER - TY - JOUR AB - Sensors able to record large bowel physiology and biochemistry in situ in awake rodents are lacking. Microdialysis is a mini-invasive technique that may be utilized to continuously deliver or recover low-molecular substances from various tissues. In this experiment we evaluated the feasibility of in vivo microdialysis to monitor extracellular fluid chemistry in the descending colon submucosa of conscious, freely moving rodents. Following surgical implantation of a microdialysis probe, male Wistar rats were housed in metabolic cages where they were analgized and clinically followed for four days with free access to standard diet and water. To assess local microcirculation and probe function, glucose, lactate, glucose-to-lactate ratio and urea clearance were determined in the dialysates from the three postoperative days with focus on the final 24-h period. In an attempt to mitigate the expected tissue inflammatory response, one group of animals had the catheters perfused with 5-ami-nosalicylic acid-enriched medium with final concentration 1 ?mol/L. For verification of probe position and the assessment of the surrounding foreign body reaction, standard histological and immunohistochemical methods were employed. Microdialysis of rat gut is associated with considerable technical challenges that may lead to the loss of probe function and high drop-out rate. In this setting, limited data did not allow to draw any firm conclusion regarding local anti-inflammatory effectiveness of 5-aminosalicylic acid perfusion. Although intestinal microdialysis may be suitable for larger anesthetized animals, low reproducibility of the presented method compromises its routine experimental use in awake and freely moving small-sized rodents. © 2018 Cibicek et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. AD - Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic Department of Histology and Embryology, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic Department of Clinical Biochemistry, University Hospital, Olomouc, Czech Republic Department of Pharmacology, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic AU - Cibicek, N. AU - Ehrmann, J. AU - Proskova, J. AU - Vecera, R. C7 - e0191041 DB - Scopus DO - 10.1371/journal.pone.0191041 IS - 1 M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2018 ST - Critical evaluation of colon submucosal microdialysis in awake, mobile rats T2 - PLoS ONE TI - Critical evaluation of colon submucosal microdialysis in awake, mobile rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85040369843&doi=10.1371%2fjournal.pone.0191041&partnerID=40&md5=a8a269f4a8e7222ad57370ac7c41a33a VL - 13 ID - 1104 ER - TY - JOUR AB - A right-sided ventriculoperitoneal (VP) shunt was placed in patient with congenital hydrocephalous in the first month of life. Three-month review visit showed no improvement and after evaluation and computerised tomogram (CT) scan brain, another VP shunt was placed on the left side without handling the previous right sided VP shunt. Patient did not improve and again presented with fever and fits. CT scan brain with and without contrast was repeated, which showed bilateral subdural empyema and right-sided cranially migrated VP shunt. Cerebrospinal fluid (CSF) analysis demonstrated infection. Bilateral burr hole drainage of subdural empyema with subsequent removal of right-sided migrated VP shunt was done. Cranial end of left-sided VP shunt was converted into external ventricular drain (EVD) and its abdominal end removed. Patient was placed on intravenous as well as intraventricular antibiotics through the EVD. Later, right-sided VP shunt was placed after clearance of infection. Regular follow-up showed that the patient is doing well. © 2015 College of Physicians & Surgeons Pakistan. AD - Department of Neurosurgery, Valley Medical Complex, Abbottabad, Pakistan AU - Rafiq, M. F. A. DB - Scopus DO - 10.29271/jcpsp.2018.07.572 IS - 7 KW - Congenital hydrocephalus Infection Subdural empyema Ventriculoperitoneal shunt migration M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 SP - 572-573 ST - Cranially migrated ventriculoperitoneal shunt in patient with bilateral subdural empyema T2 - Journal of the College of Physicians and Surgeons Pakistan TI - Cranially migrated ventriculoperitoneal shunt in patient with bilateral subdural empyema UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049168972&doi=10.29271%2fjcpsp.2018.07.572&partnerID=40&md5=99a3b9498441bcdcb1e1da706181214f VL - 28 ID - 1070 ER - TY - JOUR AB - Peri-prosthetic infection (PPI) poses a serious threat to the continued health of any patients implanted with foreign material. Tethering anti-microbials to the surface of implanted materials for the prevention of PPI might ultimately prove to be the safest and most cost-effective strategy. PPIs can be the result of infection by either gram-positive bacteria (GPB) or gram-negative bacteria (GNB), or both. Thus, broad spectrum coverage will be ultimately required. Previous work has shown the efficacy of anti-microbial tethered surfaces. This study sought to show that antibiotics effective against both GPB and GNB could be tethered in combination to morselized bone. Vancomycin (Vanc) and tetracycline (Tet) were covalently bound to demineralized, morselized rat bone. Immunohistochemistry showed that both antibiotics were attached to allograft individually as well as in combination. To test the hypothesis that covalently attached Vanc and Tet will prevent bacterial colonization by either type of bacteria, surfaces were challenged by both S. aureus and E. coli. The antibacterial properties and efficacy were determined using confocal microscopy and colony counting. Vanc tethered bone prevented colonization by S. aureus, and Tet tethered bone prevented colonization by E. coli. A combination of both antibiotics prevented colonization by both species. These results indicate that covalent attachment of combinations of broad spectrum antibiotics to bone allograft could potentially prevent PPIs. AD - N. Swisher, Anatomy, Philadelphia College of Osteopathic Medicine, Philadelphia, PA, United States AU - Swisher, N. AU - Adams, C. AU - Dattilo, V. AU - Saunders, R. DB - Embase IS - 1 KW - antibiotic agent tetracycline vancomycin bone allograft bone Escherichia coli prosthesis infection human allograft foreign body prevention infection patient Gram negative bacterium rat immunohistochemistry confocal microscopy hypothesis bacterial colonization bacterium Gram positive bacterium health antibacterial activity species L1 - internal-pdf://0719885386/922.19.abstract.txt LA - English M3 - Conference Abstract N1 - L71418639 2014-04-23 PY - 2014 SN - 1530-6860 ST - Covalent attachment of antibiotics to bone allograft T2 - FASEB Journal TI - Covalent attachment of antibiotics to bone allograft UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71418639&from=export VL - 28 ID - 449 ER - TY - JOUR AN - 21090541 DA - Aug DP - NLM ET - 2010/11/26 IS - 3 KW - Appendectomy Cesarean Section Female Foreign-Body Reaction/etiology Homicide/*legislation & jurisprudence Humans Infant, Newborn Kentucky Malpractice/*legislation & jurisprudence Obstetric Labor, Premature/*etiology Operating Room Nursing/*legislation & jurisprudence Pregnancy Surgical Sponges/*adverse effects LA - eng N1 - Journal Article Legal Case United States Nurs Law Regan Rep. 2010 Aug;51(3):1. PY - 2010 SN - 1528-848X (Print) 1528-848x SP - 1 ST - Courts rejected RIL: did nurses botch sponge count? Baxter v. Ash Samaritan Hospital, LLC, 2008-CA-000541-MR KYCA (1/15/2010)-KY T2 - Nurs Law Regan Rep TI - Courts rejected RIL: did nurses botch sponge count? Baxter v. Ash Samaritan Hospital, LLC, 2008-CA-000541-MR KYCA (1/15/2010)-KY VL - 51 ID - 104 ER - TY - JOUR AN - 105008866. Language: English. Entry Date: 20101025. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 3 KW - Surgical Sponges Childbirth, Premature Infant Mortality Courts -- Legislation and Jurisprudence -- Kentucky Malpractice -- Legislation and Jurisprudence -- Kentucky Surgical Count Procedure Childbirth Appendectomy Jury Nursing Role Female Pregnancy Kentucky N1 - legal case. Journal Subset: Blind Peer Reviewed; Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Legal Case: Baxter v. Ash Samaritan Hospital, LLC, 2008-CA-000541-MR KYCA [2010 KY]. NLM UID: 100936959. PMID: NLM21090541. PY - 2010 SN - 1528-848X SP - 1-1 ST - Courts Rejected RIL: Did Nurses Botch Sponge Count? T2 - Nursing Law's Regan Report TI - Courts Rejected RIL: Did Nurses Botch Sponge Count? UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105008866&site=ehost-live&scope=site VL - 51 ID - 933 ER - TY - JOUR AN - 106701677. Language: English. Entry Date: 20040213. Revision Date: 20150820. Publication Type: Journal Article. Journal Subset: Australia & New Zealand AU - Berryman, R. DB - ccm DP - EBSCOhost IS - 1 KW - Perioperative Nursing -- Standards -- New South Wales Surgical Count Procedure -- Standards -- New South Wales Australian College of Operating Room Nurses -- Standards Liability, Legal -- United States New South Wales Surgical Instruments Surgical Sponges Treatment Errors United States N1 - Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. PY - 2003 SN - 1448-7535 SP - 16-21 ST - Counting standards in NSW operating theatres T2 - ACORN: The Journal of Perioperative Nursing in Australia TI - Counting standards in NSW operating theatres UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106701677&site=ehost-live&scope=site VL - 16 ID - 870 ER - TY - JOUR AB - BACKGROUND: Retained surgical items (RSIs), such as a sponge, instrument, or needle, after a surgery or invasive procedure is an uncommon but potentially serious event associated with significant morbidity and mortality. A 27-year-old woman was discovered to have a retained vaginal sponge a week after she underwent the repair of a vaginal tear following normal vaginal delivery. The retained sponge was removed with no further complications. ROOT CAUSE ANALYSIS: The fundamental error involved the obstetric team's failure to perform the standard protocol of counting sponges before, as well as after, the procedure. This was attributed to a lack of reminders to perform the count, relatively recent implementation of the sponge-count policy, and a breakdown in teamwork and communication between physicians and nurses. CORRECTIVE ACTIONS: The corrective actions focused on systems improvement, as opposed to the human error of the memory lapse. The sponge-counting process was reinforced by incorporating a sign-out at the end of obstetric procedures to ensure that the counts have been done and any discrepancies addressed. A specialized delivery note with mandatory field to document sponge count was implemented in the electronic health record as an additional reminder. All staff participated in a teamwork and communication training program. TRACKING COMPLIANCE: Since the incident's occurrence in 2010, the staff has demonstrated 100% compliance with the corrective actions, and a retained surgical item complication has not recurred. CONCLUSION: Individual accountability must be balanced with systems improvement, given that most medical errors are a result of fallible humans working in chaotic, unpredictable, and complex clinical environment. AD - Kings County Hospital Center, USA. agrawal.abha@gmail.com AN - 23240265 AU - Agrawal, A. DA - Dec DO - 10.1016/s1553-7250(12)38074-4 DP - NLM ET - 2012/12/18 IS - 12 KW - Adult *Delivery, Obstetric Female Foreign Bodies/*etiology Humans Medical Errors/*adverse effects Root Cause Analysis *Surgical Sponges Tertiary Care Centers LA - eng N1 - Agrawal, Abha Case Reports Journal Article Netherlands Jt Comm J Qual Patient Saf. 2012 Dec;38(12):566-74. doi: 10.1016/s1553-7250(12)38074-4. PY - 2012 SN - 1553-7250 (Print) 1553-7250 SP - 566-74 ST - Counting matters: lessons from the root cause analysis of a retained surgical item T2 - Jt Comm J Qual Patient Saf TI - Counting matters: lessons from the root cause analysis of a retained surgical item VL - 38 ID - 131 ER - TY - JOUR AB - Patients in whom a sponge or instruments is left after surgery may suffer complications including pain, infection, abscess, or intestinal obstruction. Consequences or retained items for surgical team members may include malpractice lawsuits and adverse actions from the National Practitioner Data Bank and state licensing board. Adherence to AORN recommended practices for counting and facility counting policies can protect both patients and practitioners. AD - Harry S. Truman Medical Center, Comlumbia, MO, USA. AN - 18323022 AU - Jackson, S. AU - Brady, S. DA - Feb DO - 10.1016/j.aorn.2007.07.023 DP - NLM ET - 2008/03/08 IS - 2 KW - Foreign Bodies/etiology/*prevention & control Health Facility Administration Humans Medical Errors/legislation & jurisprudence/*prevention & control Patient Care Team/legislation & jurisprudence Surgical Instruments/*adverse effects Surgical Sponges/*adverse effects United States LA - eng N1 - Jackson, Sarah Brady, Sharon Case Reports Journal Article Review United States AORN J. 2008 Feb;87(2):315-21. doi: 10.1016/j.aorn.2007.07.023. PY - 2008 SN - 0001-2092 (Print) 0001-2092 SP - 315-21 ST - Counting difficulties: retained instruments, sponges, and needles T2 - Aorn j TI - Counting difficulties: retained instruments, sponges, and needles VL - 87 ID - 74 ER - TY - JOUR AB - Perioperative nurses have developed specific expert nursing care practices. 'Counting as caring' is certainly an approach in keeping with the perioperative nurse's guiding principle of beneficence (to do no harm). This article takes a retrospective look, from the first half of the last century through into the late 1960s, at the practice of counting and the influences that have changed it. AD - Clinical Practice Leader, and practicing as an RNFA, at both Kingston General Hospital and Hotel Dieu Hospital, in Kingston, Ontario AN - 106190948. Language: English. Entry Date: 20071116. Revision Date: 20150820. Publication Type: Journal Article. Journal Subset: Blind Peer Reviewed AU - Downey, C. DB - ccm DP - EBSCOhost IS - 3 KW - Caring Perioperative Nursing Surgical Count Procedure -- History Canada Insurance, Health, Reimbursement Power N1 - Canada; Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. NLM UID: 8406632. PMID: NLM17958054. PY - 2007 SN - 0712-6778 SP - 6-13 ST - Counting as caring T2 - Canadian Operating Room Nursing Journal TI - Counting as caring UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106190948&site=ehost-live&scope=site VL - 25 ID - 796 ER - TY - JOUR AN - 106746023. Language: English. Entry Date: 20040618. Revision Date: 20200708. Publication Type: Journal Article AU - Girard, N. J. DB - ccm DO - 10.1016/S0001-2092(06)60897-1 DP - EBSCOhost IS - 3 KW - Retained Instruments -- Prevention and Control Surgical Count Procedure -- Standards AORN -- Standards N1 - editorial. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PMID: NLM15074515. PY - 2004 SN - 0001-2092 SP - 575-576 ST - The countdown to safety T2 - AORN Journal TI - The countdown to safety UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106746023&site=ehost-live&scope=site VL - 79 ID - 915 ER - TY - JOUR AD - Department of Neurosurgery, University of Illinois College of Medicine at Peoria, Illinois Neurological Institute, Peoria, Illinois, USA. Electronic address: tobiasmattei@yahoo.com. Neurosurgical League, Instituto de Neurologia de Curitiba, Curitiba, Brazil. AN - 23247023 AU - Mattei, T. A. AU - Goulart, C. R. DA - Jul-Aug DO - 10.1016/j.wneu.2012.12.023 DP - NLM ET - 2012/12/19 IS - 1-2 KW - Female Humans Lumbosacral Region/*surgery Male Neurosurgical Procedures/*adverse effects Postoperative Complications/*etiology Spine/*surgery Surgical Sponges/*adverse effects LA - eng N1 - 1878-8769 Mattei, Tobias A Goulart, Carlos R Comment Letter United States World Neurosurg. 2014 Jul-Aug;82(1-2):e378-84. doi: 10.1016/j.wneu.2012.12.023. Epub 2012 Dec 14. PY - 2014 SN - 1878-8750 SP - e378-84 ST - "Count on me!": urgent public health and safety policies to avoid complications associated with foreign body retention in neurosurgical procedures, with special attention to "miscellaneous small items" T2 - World Neurosurg TI - "Count on me!": urgent public health and safety policies to avoid complications associated with foreign body retention in neurosurgical procedures, with special attention to "miscellaneous small items" VL - 82 ID - 132 ER - TY - JOUR AB - Mediastinitis is an infrequent complication after coronary artery bypass graft (CABG) that is associated with prolonged intensive care unit and hospital stay, and increased early and late morbidity and mortality. Patients with mediastinitis have an osteoporotic, fragile, and broken sternum. All foreign bodies as well as infected tissue should be removed. Osteomyelitis of sternum often perseveres after debridement for mediastinitis. In this report, we describe an unusual case of costochondritis caused by aspergillosis following off pump CABG surgery in a male patient in Yazd-Iran. © 2013 Tehran University of Medical Sciences. All rights reserved. AD - Department of Cardiovascular Surgery, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran Yazd Cardiovascular Researches Center, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Department of Cardiovascular Surgery, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran AU - Mirhosseini, S. J. AU - Salehi, M. AU - Ali-Hassan-Sayegh, S. AU - Forouzannia, S. K. AU - Karimi-Bondarabadi, A. A. DB - Scopus IS - 10 KW - Aspergillus flavus Cardiac surgery Costochondritis M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2013 SP - 733-735 ST - Costochondritis caused by Aspergillus flavus following cardiac surgery T2 - Acta Medica Iranica TI - Costochondritis caused by Aspergillus flavus following cardiac surgery UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84900323436&partnerID=40&md5=dc10119ba8f23e70b868d2b7e4512fc1 VL - 51 ID - 1343 ER - TY - JOUR AN - 126778523. Language: English. Entry Date: 20171219. Revision Date: 20171220. Publication Type: Article DB - ccm DP - EBSCOhost IS - 327 KW - Surgical Instruments -- Statistics and Numerical Data -- United Kingdom Surgical Count Procedure -- Economics United Kingdom Cost Benefit Analysis N1 - pictorial. Journal Subset: Allied Health; Blind Peer Reviewed; Europe; Nursing; Peer Reviewed; UK & Ireland. PY - 2017 SN - 1747-728X SP - 9-9 ST - The "Cost" of Missing Medical Instruments T2 - Operating Theatre Journal TI - The "Cost" of Missing Medical Instruments UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=126778523&site=ehost-live&scope=site ID - 771 ER - TY - JOUR AB - BACKGROUND: Emergency surgery increases the risk of a retained surgical sponge (RSS) by 9-fold. In most cases, surgical counts are falsely reported as correct. We hypothesized that the institutional costs resulting from a RSS would make routine intraoperative radiography (IOR) more cost-effective than surgical counts in preventing RSS after emergent open cavity cases. METHODS: A cost-effectiveness analysis was performed to compare routine IOR with surgical counts after emergent open cavity operations. Parameter estimates were obtained from the literature, expert opinion via a standardized survey, and existing institutional data. RESULTS: Routine IOR was the preferred strategy ($705 vs $1155 per patient) under the assumptions of the base case. The surgical count strategy was dominated by the institutional costs incurred after a RSS. Routine IOR was preferential as long as the sensitivity of surgical counts was less than 98% and the legal fees were more than $44,000 per case of RSS. CONCLUSIONS: Routine IOR is a simple, cost-effective option to reduce the occurrence of this preventable medical error. Institutional costs and legal fees associated with RSS dominate the cost of the surgical count strategy, making routine IOR a more cost-effective strategy than surgical counts given the best available parameter estimates. AD - Department of Surgery, Division of Trauma and Surgical Critical Care, Vanderbilt University Medical Center, Nashville, TN, USA. lesly.dossett@vanderbilt.edu AN - 18656641 AU - Dossett, L. A. AU - Dittus, R. S. AU - Speroff, T. AU - May, A. K. AU - Cotton, B. A. DA - Aug DO - 10.1016/j.surg.2008.03.012 DP - NLM ET - 2008/07/29 IS - 2 KW - Abdomen/surgery Cost-Benefit Analysis Decision Support Techniques Emergencies Foreign Bodies/*diagnostic imaging/economics Hospital Costs Humans Intraoperative Period Medical Errors/economics/*prevention & control Radiography/*economics Sensitivity and Specificity *Surgical Sponges Thoracic Surgical Procedures LA - eng N1 - 1532-7361 Dossett, Lesly A Dittus, Robert S Speroff, Theodore May, Addison K Cotton, Bryan A T32 HS 013833/HS/AHRQ HHS/United States Journal Article Research Support, U.S. Gov't, P.H.S. United States Surgery. 2008 Aug;144(2):317-21. doi: 10.1016/j.surg.2008.03.012. Epub 2008 Jun 5. PY - 2008 SN - 0039-6060 SP - 317-21 ST - Cost-effectiveness of routine radiographs after emergent open cavity operations T2 - Surgery TI - Cost-effectiveness of routine radiographs after emergent open cavity operations VL - 144 ID - 80 ER - TY - JOUR AB - BACKGROUND: Integra, a dermal replacement template consisting of bovine collagen, chondroitin-6-sulfate, and a silastic sheet is a postexcisional treatment for deep partial to full thickness burns where autograft is limited. This study correlates Integra histology and quantitative microbiology cultures with clinical outcomes after autografting. METHODS: Charts of 29 burn patients who underwent Integra treatment and neodermis biopsy at the time of ultra thin autografting were reviewed. We analyzed microbial contamination, inflammatory reaction, and autograft take. RESULTS: The mean burn size and age were 43% total body surface area and 39 years old, respectively. In quantitative neodermis cultures, 90% of samples had bacterial growth; nine samples (31%) had > 10(5) colony forming units per gram. The most common organism was Staphylococcus aureus (31%). Patients with quantitative bacterial counts >10(5) CFU/g received targeted systemic antibiotics. Integra take (83%) and autograft take (92%) were acceptable even in patients with high bacterial counts (78% Integra take; 86% autograft take). More than 50% of biopsies had dermal regeneration similar to normal dermis; foreign body reactions were unusual. Histologic evidence of inflammation, especially polymorphonuclear cells, was increased in biopsies with high bacterial counts. CONCLUSION: Integra and autograft take can be acceptable even with high bacterial counts if wounds are treated with appropriate targeted topical and systemic antibiotics in the presence of microbial contamination. Neodermis biopsies showed fibrous in-growth congruent with existing Integra fibers with minimal foreign body reaction. These data support Integra use as a safe and effective treatment modality in patients with major burns. AD - University of Washington Burn Center, Department of Surgery, University of Washington, Seattle, Washington 98104, USA. AN - 17099531 AU - Muangman, P. AU - Deubner, H. AU - Honari, S. AU - Heimbach, D. M. AU - Engrav, L. H. AU - Klein, M. B. AU - Gibran, N. S. DA - Nov DO - 10.1097/01.ta.0000195982.71400.84 DP - NLM ET - 2006/11/14 IS - 5 KW - Administration, Topical Adult Bacitracin/therapeutic use Biocompatible Materials/*therapeutic use Burns/*therapy *Chondroitin Sulfates *Collagen Colony Count, Microbial Drug Combinations Female Humans Male Neomycin/therapeutic use Polymyxin B/therapeutic use Retrospective Studies Skin Transplantation Skin, Artificial/*microbiology Surgical Wound Infection/*microbiology/prevention & control Treatment Outcome LA - eng N1 - Muangman, Pornprom Deubner, Heike Honari, Shari Heimbach, David M Engrav, Loren H Klein, Matthew B Gibran, Nicole S Journal Article United States J Trauma. 2006 Nov;61(5):1212-7. doi: 10.1097/01.ta.0000195982.71400.84. PY - 2006 SN - 0022-5282 (Print) 0022-5282 SP - 1212-7 ST - Correlation of clinical outcome of integra application with microbiologic and pathological biopsies T2 - J Trauma TI - Correlation of clinical outcome of integra application with microbiologic and pathological biopsies VL - 61 ID - 62 ER - TY - JOUR AB - Cochlear implantation is an effective, established procedure for patients with profound deafness. Although implant electrodes have been considered as biocompatible prostheses, surgical insertion of the electrode induces various changes within the cochlea. Immediate changes include insertional trauma to the cochlea. Delayed changes include a tissue response consisting of inflammation, fibrosis and neo-osteogenesis induced by trauma and an immunologic reaction to a foreign body. The goal of this study was to evaluate the effect of these delayed changes on the word recognition scores achieved post-operatively. Seventeen temporal bones from patients who in life had undergone cochlear implantation were prepared for light microscopy. We digitally calculated the volume of fibrous tissue and new bone within the cochlea using Amira(®) three-dimensional reconstruction software and assessed the correlations of various clinical and histologic factors. The postoperative CNC word score was positively correlated with total spiral ganglion cell count. Fibrous tissue and new bone were found within the cochlea of all seventeen specimens. The postoperative CNC word score was negatively correlated with the % volume of new bone within the scala tympani, scala media/vestibuli and the cochlea, but not with the % volume of fibrous tissue. The % volume of new bone in the scala media/vestibuli was positively correlated with the degree of intracochlear insertional trauma, especially trauma to the basilar membrane. Our results revealed that the % volume of new bone as well as residual total spiral ganglion cell count are important factors influencing post-implant hearing performance. New bone formation may be reduced by limiting insertional trauma and increasing the biocompatibility of the electrodes. AD - Human Otopathology Laboratory, Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA; Department of Otolaryngology, Harvard Medical School, Boston, MA, USA. Human Otopathology Laboratory, Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA; Department of Otolaryngology, Harvard Medical School, Boston, MA, USA. Electronic address: joseph_nadol@meei.harvard.edu. AN - 27371868 AU - Kamakura, T. AU - Nadol, J. B., Jr. C2 - PMC5018452 C6 - NIHMS805471 DA - Sep DO - 10.1016/j.heares.2016.06.015 DP - NLM ET - 2016/07/03 KW - Aged Aged, 80 and over Basilar Membrane/*pathology Cochlea/*pathology Cochlear Implantation *Cochlear Implants Deafness/pathology Electrodes Electrodes, Implanted Female Hearing Humans Image Processing, Computer-Assisted Imaging, Three-Dimensional Male Middle Aged Scala Tympani/*surgery Scala Vestibuli *Speech Discrimination Tests Spiral Ganglion/pathology Temporal Bone/*pathology *Cochlear implant *Fibrous tissue *Human inner ear *Insertional trauma *New bone *Word recognition score LA - eng N1 - 1878-5891 Kamakura, Takefumi Nadol, Joseph B Jr R01 DC000152/DC/NIDCD NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Hear Res. 2016 Sep;339:132-41. doi: 10.1016/j.heares.2016.06.015. Epub 2016 Jun 29. PY - 2016 SN - 0378-5955 (Print) 0378-5955 SP - 132-41 ST - Correlation between word recognition score and intracochlear new bone and fibrous tissue after cochlear implantation in the human T2 - Hear Res TI - Correlation between word recognition score and intracochlear new bone and fibrous tissue after cochlear implantation in the human VL - 339 ID - 180 ER - TY - JOUR AD - R.E. Miller AU - Miller, R. E. DB - Medline IS - 4 KW - human methodology note peroperative care postoperative complication statistics surgical sponge LA - English M3 - Note N1 - L127256256 1997-05-18 PY - 1997 SN - 0003-4932 SP - 442 ST - Correct surgical sponge count T2 - Annals of surgery TI - Correct surgical sponge count UR - https://www.embase.com/search/results?subaction=viewrecord&id=L127256256&from=export VL - 225 ID - 662 ER - TY - JOUR AB - Implantation of a Molteno drainage shunt has been shown to be effective in advanced glaucoma. Foreign substances within the anterior chamber have been known to cause progressive endothelial cell loss. We undertook a study to evaluate the endothelial effects of an indwelling Molteno drainage shunt. Nineteen patients who underwent uneventful implantation of a Molteno drainage shunt for advanced aphakic or pseudophakic glaucoma were followed up. Serial endothelial cell counts were obtained in a masked fashion. During follow-up periods ranging from 5.4 to 25.7 months, endothelial cell loss averaged two cells per square millimeter per postoperative month with a 95% confidence interval of positive seven cells to negative ten cells per square millimeter per postoperative month. No clinically significant progressive trend in endothelial cell loss was seen in patients undergoing uncomplicated Molteno drainage procedures. Larger sample sizes with longer follow-up will be necessary to establish whether a Molteno drainage shunt causes clinically remarkable endothelial cell loss. AD - Department of Ophthalmology, Kresge Eye Institute, Wayne State Univ. School of Medicine, 4717 St. Antoine, Detroit, MI 48201, United States AU - McDermott, M. L. AU - Swendris, R. P. AU - Shin, D. H. AU - Juzych, M. S. AU - Cowden, J. W. DB - Scopus DO - 10.1016/S0002-9394(14)73530-5 IS - 1 M3 - Article N1 - Cited By :60 Export Date: 10 November 2020 PY - 1993 SP - 93-96 ST - Corneal endothelial cell counts after Molteno implantation T2 - American Journal of Ophthalmology TI - Corneal endothelial cell counts after Molteno implantation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027534383&doi=10.1016%2fS0002-9394%2814%2973530-5&partnerID=40&md5=a71f921ae9c449ba4d80ba19ef662684 VL - 115 ID - 1730 ER - TY - JOUR AN - 104129226. Language: English. Entry Date: 20131227. Revision Date: 20200708. Publication Type: Journal Article AU - Ogg, Mary J. DB - ccm DO - 10.1016/j.aorn.2013.10.007 DP - EBSCOhost IS - 1 KW - Sutures Needles Needlestick Injuries -- Prevention and Control Occupational Exposure -- Prevention and Control Surgical Count Procedure Protective Clothing Education, Continuing (Credit) Occupational Safety United States Occupational Safety and Health Administration Bloodborne Pathogens Professional Compliance Perioperative Nursing Surgeons Equipment Safety Staff Development Registered Nurses Cesarean Section Hospital Policies Patient Safety Asepsis Surgical Wound Infection -- Prevention and Control Retained Instruments -- Prevention and Control Protective Devices -- Utilization N1 - questions and answers; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Patient Safety; Perioperative Care. NLM UID: 0372403. PY - 2014 SN - 0001-2092 SP - 166-175 ST - CONTINUING EDUCATION CLINICAL ISSUES T2 - AORN Journal TI - CONTINUING EDUCATION CLINICAL ISSUES UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104129226&site=ehost-live&scope=site VL - 99 ID - 731 ER - TY - JOUR DB - Scopus IS - 10 M3 - Article N1 - Export Date: 10 November 2020 PY - 2009 SP - 1836-1843 ST - Consultation section. Cataract surgical problem T2 - Journal of cataract and refractive surgery TI - Consultation section. Cataract surgical problem UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-70350434347&partnerID=40&md5=a3df0c4cc43805f592a90f85db007be7 VL - 35 ID - 1485 ER - TY - JOUR AD - Nurse. Master in Nursing. Quality manager of Hospital São Benedito. Cuiabá, MT, Brazil Nurse. PhD in Nursing. Professor of Nursing at Universidade Federal do Mato Grosso. Cuiabá, MT, Brazil AN - 121400572. Language: English. Entry Date: 20180430. Revision Date: 20190212. Publication Type: Article AU - Lopes Souza, Gisele Silva AU - Rosa Ribeiro, Mara Regina DB - ccm DO - 10.5380/ce.v22i1.46435 DP - EBSCOhost KW - Instrument Construction Policy and Procedure Manuals Checklists Patient Safety Learning Educational Technology Operating Rooms Education, Continuing Semi-Structured Interview Professional Knowledge Thematic Analysis Handwashing Patient Identification Surgical Count Procedure N1 - research. Journal Subset: Mexico & Central/South America; Nursing; Peer Reviewed. NLM UID: 9713482. PY - 2017 SN - 1414-8536 SP - 01-05 ST - CONSTRUCTION OF A SURGICAL SAFETY MANUAL FOR HEALTH PROFESSIONALS T2 - Cogitare Enfermagem TI - CONSTRUCTION OF A SURGICAL SAFETY MANUAL FOR HEALTH PROFESSIONALS UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=121400572&site=ehost-live&scope=site ID - 714 ER - TY - JOUR AB - We reviewed the clinical benefits of hospitalization, esophagogastroduodenoscopy, and surgical intervention for ingested foreign bodies in adults. Patients with esophageal foreign bodies were not included in the study group. A 10-year experience is reported. Each patient's physical examination findings at presentation, white blood cell count, length of hospital stay, number and types of foreign bodies ingested, endoscopic interventions, surgical interventions, and complications were reviewed. There were 75 separate hospitalizations, all occurring in 22 male prison inmates. A total of 256 foreign bodies were ingested. Patients incurred 281 hospitalization days (average 3.7 days per admission). One patient had signs of peritonitis. White blood cell count was less than 10 K/microL in 85%. Sixty-four endoscopies were performed with removal of 79 of 163 foreign bodies (48% success rate). Five patients required general anesthesia because of a lack of cooperation. Complications occurred in four of them, one requiring laparotomy. Eight additional laparotomies were performed. One was performed for an acute abdomen on admission and one for the development of an acute abdomen after conservative management. Two were performed to remove metal bezoars. Four additional laparotomies were performed because of surgeon preference. Among the 23 patients admitted and managed conservatively, 77 (97%) of 79 foreign bodies passed spontaneously. One patient required laparotomy. Of the 256 ingested foreign bodies, 79 were removed endoscopically, 71 were removed surgically, and 106 passed spontaneously. The size, shape, and number were not predictive of the ability to transit the gastrointestinal tract. Foreign body ingestion is problematic in prison inmates. With conservative management, most foreign bodies will pass spontaneously. Endoscopy has a high failure rate and is associated with significant complications. Surgical intervention should be reserved for those who have acute conditions in the abdomen or large bezoars. AD - Department of Surgery, University of Wisconsin Hospital, Madison, Wisconsin 53792, USA. AN - 12023005 AU - Weiland, S. T. AU - Schurr, M. J. DA - May-Jun DO - 10.1016/s1091-255x(01)00027-0 DP - NLM ET - 2002/05/23 IS - 3 KW - Adult *Endoscopy, Gastrointestinal Foreign Bodies/surgery/*therapy Humans Length of Stay Male Middle Aged Prisoners Treatment Outcome LA - eng N1 - Weiland, Steven T Schurr, Michael J Journal Article United States J Gastrointest Surg. 2002 May-Jun;6(3):496-500. doi: 10.1016/s1091-255x(01)00027-0. PY - 2002 SN - 1091-255X (Print) 1091-255x SP - 496-500 ST - Conservative management of ingested foreign bodies T2 - J Gastrointest Surg TI - Conservative management of ingested foreign bodies VL - 6 ID - 37 ER - TY - JOUR AB - Objective: To describe the conjunctival scrape cytology findings in patients with chronic graft-versus-host disease (GVHD). Study Design: Conjunctival scrape cytology was performed to find the cause of conjunctivitis in 20 patients with chronic conjunctival GVHD. All patients had chronic ocular symptoms such as foreign body sensation, burning, tearing and red eye. Twenty age-matched bone marrow transplant recipients without GVHD were included as a control group. Results: Scraping yielded a sufficient number of cells. Cytologic findings included atypical epithelial cells; loss of goblet cells; epithelial cells with vacuolated or coarse, granular cytoplasm; squamous metaplasia; and a prominent inflammatory background. Conclusion: Conjunctival scrape cytology yields a sufficient number of cells in conjunctival GVHD. This method is useful for the diagnosis of complications associated with conjunctival GVHD and may be helpful in evaluating the response to treatment options. © The International Academy of Cytology. AD - Department of Ophthalmology, Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Department of Pathology, Cancer Research Institute, Shiraz University of Medical Sciences, Shiraz, Iran Department of Hematology and Hematology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran AU - Hosseini, H. AU - Kumar, P. V. AU - Geramizadeh, B. AU - Nowroozizadeh, B. AU - Ramzi, M. DB - Scopus DO - 10.1159/000325034 IS - 3 KW - Bone marrow transplantation Conjunctival disease Graft-versus-host disease Scrape cytology M3 - Article N1 - Cited By :9 Export Date: 10 November 2020 PY - 2010 SP - 272-276 ST - Conjunctival scrape cytology findings in patients with chronic graft-versus-host disease following allogeneic bone marrow transplantation T2 - Acta Cytologica TI - Conjunctival scrape cytology findings in patients with chronic graft-versus-host disease following allogeneic bone marrow transplantation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77953218092&doi=10.1159%2f000325034&partnerID=40&md5=a51489ee4df9b7501c6e37a78d831083 VL - 54 ID - 1477 ER - TY - JOUR AB - PURPOSE: To evaluate the cytologic features of conjunctival epithelium in anophthalmic sockets with an ocular prosthesis, using an impression cytology technique and to determine the clinical factors associated with these changes. METHODS: In a prospective case-controlled study, 40 consecutive unilateral anophthalmic patients who wore an ocular prosthesis were recruited. A questionnaire on the care of the prosthesis included total wearing period, frequency of cleaning, frequency of polishing, cleaning solution, and eye drop use. The degree of inflammation of the anophthalmic conjunctival socket was evaluated. Impression cytology specimens were taken from the upper tarsal conjunctiva, the bulbar conjunctiva, and the lower tarsal conjunctiva of each socket, and from the contralateral eye (to serve as an internal matched control). The goblet cell density and the nucleus-to-cytoplasm ratio of the epithelial cells were measured. The relevance of these conjunctival cytologic features to the various factors of prosthesis care or conjunctival inflammation was analyzed. RESULTS: In the anophthalmic sockets, the conjunctiva showed squamous metaplasia at all 3 areas sampled. The goblet cell density was significantly decreased and the nucleus-to-cytoplasm ratio of the epithelial cells was significantly increased compared with the control eyes (p < 0.05, on all 3 areas sampled, Wilcoxon signed rank test). These conjunctival cytologic changes were not significantly associated with total wearing time, frequency of polishing, cleaning solution, or eye drops use (p > 0.05, Spearman's correlation test). CONCLUSIONS: Squamous metaplasia with decreased goblet cell density and increased nucleus-to-cytoplasm ratio occurred in anophthalmic conjunctival sockets but was not associated with particular aspects of prosthesis care. © 2008 The American Society of Opthalmic Plastic and Reconstructive Surgery, Inc. AD - S-Eye Center, Ansan, South Korea Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, South Korea Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Boramae Hospital, Seoul, South Korea Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea Department of Ophthalmology, Dongguk University College of Medicine, Dongguk University International Hospital, Ilsan, South Korea AU - Kim, J. H. AU - Lee, M. J. AU - Choung, H. K. AU - Kim, N. J. AU - Hwang, S. W. AU - Sung, M. S. AU - Khwarg, S. I. DB - Scopus DO - 10.1097/IOP.0b013e3181788dff IS - 4 M3 - Article N1 - Cited By :24 Export Date: 10 November 2020 PY - 2008 SP - 290-295 ST - Conjunctival cytologic features in anophthalmic patients wearing an ocular prosthesis T2 - Ophthalmic Plastic and Reconstructive Surgery TI - Conjunctival cytologic features in anophthalmic patients wearing an ocular prosthesis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-48849102069&doi=10.1097%2fIOP.0b013e3181788dff&partnerID=40&md5=e29c37fa49f33675c457152cafd6c72f VL - 24 ID - 1525 ER - TY - JOUR AB - SESSION TITLE: Tuesday Medical Student/Resident Case Report Posters SESSION TYPE: Med Student/Res Case Rep Postr PRESENTED ON: 10/22/2019 01:00 PM - 02:00 PM INTRODUCTION: Congenital Bronchial Atresia (CBA) is a rare developmental anomaly, results from focal interruption of bronchus along with the formation of mucocele (mucus filled bronchus). It often presents in adulthood, as an incidental finding on radiography or recurrent pneumonia. Computed tomography (CT) angiogram of the chest remains the investigation of choice in the diagnosis of CBA while bronchoscopy should be done to rule out other etiologies of hyperinflation. Management of CBA is conservative for asymptomatic individuals while surgery is reserved for individuals who have the recurrent infection and severe symptoms. CASE PRESENTATION: 19-year-old male with no known past medical history presented to the ED for evaluation of dry cough and subjective fever for 5 days. Patient denied any shortness of breath, hemoptysis, chest pain, night sweats, weight loss or change in appetite. Patient was not taking any medication at home. Past surgical and family history was not significant. Patient denied smoking, alcohol use and any illicit drug abuse. On admission, he was afebrile, hemodynamically stable and saturating 99% on room air. In terms of labs, white cell count was elevated initially and then trended down; rest of the labs including molecular flu, pro-calcitonin, legionella antigen, mycoplasma antigen, respiratory syncytial virus PCR and blood culture were negative. Chest x-ray showed hyperlucency and decreased vascularity in the left upper lung zone along with consolidation in the left lower lobe. Patient was started on antibiotics and treated for community-acquired pneumonia. CT angiogram of the chest (1) showed round soft tissue density suggestive of mucoid impaction of the left bronchus likely mucocele along with hyperlucent left upper lobe and hypoplastic vasculature consistent with bronchial atresia (Figure 1 and 2). Bronchoscopy was normal which was done to rule out other etiologies like foreign body, bronchial adenoma, and lung cancer. V/Q scan showed no ventilation and perfusion to the majority of left upper lobe (figure 3). Patient showed signs of clinical improvement and discharged on oral antibiotics with outpatient follow up. DISCUSSION: CBA is a benign and rare entity with characteristic imaging finding resembling other serious underlying disease. Management can range from conservative measure to the surgery of an involved segment of the lung. Therefore, it is imperative to understand the nature of the disease and counsel the patient accordingly. CONCLUSIONS: Although benign entity, CBA should be kept in the differential especially in young patients who present with hyperinflation of one or more segment of lung which might cause compression atelectasis and/or pneumonia of the other adjacent segments as it presented in our case. CTA of the chest is usually the modality to diagnose with bronchoscopy and V/Q scan to guide further management. Reference #1: Psathakis K, Eleftheriou D, Boulas P, Mermigkis C, Tsintiris K. Congenital bronchial atresia presenting as a cavitary lesion on chest radiography: a case report. Cases J. 2009;2(1):17. Published 2009 Jan 7. Reference #2: Mahajan AK, Rahimi R, Vanderlaan P, Folch E, Gangadharan S, et al. (2017) Unique Approach to Diagnosing and Treating Congenital Bronchial Atresia (CBA): A Case Series. J Pulm Respir Med 7:402. DISCLOSURES: No relevant relationships by Anas Al-khateeb, source=Web Response No relevant relationships by mohammed halabiya, source=Web Response No relevant relationships by Muhammad Hussain, source=Web Response No relevant relationships by Muqueet Kadri, source=Web Response No relevant relationships by Richard Miller, source=Web Response No relevant relationships by Hari Sharma, source=Web Response AU - Hussain, M. AU - Halabiya, M. AU - Kadri, M. AU - Al-khateeb, A. AU - Sharma, H. AU - Miller, R. DB - Embase DO - 10.1016/j.chest.2019.08.1345 IS - 4 KW - antibiotic agent antigen calcitonin endogenous compound illicit drug adult alcohol consumption ambient air appetite atelectasis atresia blood culture body weight loss bronchoscopy cancer patient cancer surgery case report case study clinical article community acquired pneumonia compression computer assisted tomography conference abstract congenital disorder coughing diagnosis drug abuse drug therapy duck dyspnea family history fever follow up foreign body hemoptysis human Human respiratory syncytial virus hyperinflation influenza Legionella leukocyte count lung adenoma lung cancer male mucocele Mycoplasma night sweat nonhuman outpatient perfusion polymerase chain reaction recurrent infection smoking soft tissue thorax pain thorax radiography vascularization young adult LA - English M3 - Conference Abstract N1 - L2002983795 2019-10-02 PY - 2019 SN - 1931-3543 0012-3692 SP - A1522 ST - CONGENITAL BRONCHIAL ATRESIA: A RARE ENTITY T2 - Chest TI - CONGENITAL BRONCHIAL ATRESIA: A RARE ENTITY UR - https://www.embase.com/search/results?subaction=viewrecord&id=L2002983795&from=export http://dx.doi.org/10.1016/j.chest.2019.08.1345 VL - 156 ID - 303 ER - TY - JOUR AB - Objective: Evaluation of corneal morphology by confocal microscopy after vitreoretinal surgery complicated by passage of silicone oil into the anterior chamber. Design: Case series (case control study). Methods: Eight patients (eight eyes) who had undergone vitreoretinal surgery and had silicone oil in the anterior chamber but no clinically evident corneal abnormalities made up the patient group. The control group consisted of eight patients (eight eyes) who had undergone vitreoretinal surgery with application of silicone oil tamponade but who had no silicone oil clinically observable in the anterior chamber. In vivo examination of the cornea using a ConfoScan 3 (Nidek Technologies) confocal microscope equipped with the standard 40 immersion lens was performed. Central, upper, and lower parts of the cornea were assessed separately. High-magnification evaluation of the status of corneal layers and endothelial cell density in upper parts of the cornea directly in contact with silicone oil in the anterior chamber and in parts of the cornea not in direct contact with silicone oil was carried out. Results: Alterations in corneal morphology, especially in endothelium and posterior and medium stroma, were observed. In all cases, changes were more advanced in the upper part of the cornea. Endothelial cell density was significantly decreased in upper parts of the cornea. Conclusions: In patients with silicone oil in the anterior chamber, confocal microscopy imaging reveals early morphological alterations of the cornea before their clinical manifestation. © Springer-Verlag 2006. AD - Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland Al. Wojska Polskiego 39, 05-520 Konstancin-Jeziorna, Poland AU - Szaflik, J. P. AU - Kmera-Muszyńska, M. DB - Scopus DO - 10.1007/s00417-006-0433-0 IS - 2 KW - Confocal microscopy Cornea Corneal endothelium Silicone oil Vitreoretinal surgery M3 - Article N1 - Cited By :9 Export Date: 10 November 2020 PY - 2007 SP - 210-214 ST - Confocal microscopy imaging of the cornea in patients with silicone oil in the anterior chamber after vitreoretinal surgery T2 - Graefe's Archive for Clinical and Experimental Ophthalmology TI - Confocal microscopy imaging of the cornea in patients with silicone oil in the anterior chamber after vitreoretinal surgery UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33847116587&doi=10.1007%2fs00417-006-0433-0&partnerID=40&md5=a1c35a4b2373e178e07c9c6d5f9de8c5 VL - 245 ID - 1568 ER - TY - JOUR AB - PURPOSE: To assess the efficacy, safety, and predictability of conductive keratoplasty for the treatment of corneal trauma/incision-induced hyperopic or compound astigmatism. METHODS: Thirteen eyes with corneal trauma/incision- induced astigmatism underwent conductive keratoplasty in this prospective study. The main outcome measures included distance uncorrected visual acuity (UCVA), near UCVA, best spectacle-corrected visual acuity (BSCVA), manifest refraction cylinder, keratometric astigmatism, manifest refraction spherical equivalent (MRSE), contrast sensitivity, glare sensitivity, intraocular pressure, tear break-up time, endothelial cell count, and pachymetry. Patients were followed 1 week and 1, 3, and 6 months postoperatively. RESULTS: Mean logMAR scores for distance UCVA, near UCVA, and BSCVA significantly improved from 0.87±0.31, 1.32±0.41, and 0.18±0.18, respectively, to 0.32±0.21, 0.59±0.21, and 0.08±0.11 (P≤.05), respectively, 6 months after conductive keratoplasty. Mean manifest refraction cylinder, keratometric astigmatism, and MRSE significantly reduced from 4.12±2.86 diopters (D), 4.15±2.40 D, and 0.73±2.56 D, respectively, to 1.46±1.35 D, 1.66±1.44 D, and -0.52±0.99 D (P≤.05), respectively, at 6 months postoperatively. Contrast sensitivity and glare sensitivity showed significant improvement at spatial frequencies of 1, 1.6, 2.5, 4, and 6.3 cycles per degree (P≤.05). Surgically induced astigmatism calculated by vector analysis highly correlated to target induced astigmatism (P≤.05). No severe complications occurred postoperatively. CONCLUSIONS: This study suggests that conductive keratoplasty is an effective and safe treatment for hyperopic or compound astigmatism after corneal trauma or incision. Copyright ©SLACK Incorporated. AD - W. Xu, Eye Center, Second Affiliated Hospital, Zhejiang University, No. 88 Jiefang Rd, Hangzhou 310009, China AU - Xu, W. AU - Ye, P. AU - Yao, K. AU - Ma, J. AU - Xu, H. DB - Embase Medline DO - 10.3928/1081597X-20101215-05 IS - 1 KW - adult aged article astigmatism blurred vision cell count clinical article contrast contrast enhancement cornea injury endothelium cell eye discomfort female foreign body human intraocular pressure keratometry keratoplasty male outcome assessment postoperative complication postoperative period priority journal prospective study refraction error scoring system spatial frequency discrimination surgical patient visual acuity LA - English M3 - Article N1 - L358167164 2010-02-04 2010-03-01 PY - 2010 SN - 1081-597X SP - 33-42 ST - Conductive keratoplasty for the treatment of astigmatism induced by corneal trauma or incision T2 - Journal of Refractive Surgery TI - Conductive keratoplasty for the treatment of astigmatism induced by corneal trauma or incision UR - https://www.embase.com/search/results?subaction=viewrecord&id=L358167164&from=export http://dx.doi.org/10.3928/1081597X-20101215-05 http://www.journalofrefractivesurgery.com/showPdf.asp?thing=60026 VL - 26 ID - 572 ER - TY - JOUR AD - The Townsville Hospital, 100 Angus Smith Drive, Townsville, Queensland 4810, Australia AU - Zubair, O. N. AU - Carroll, D. AU - Goodall, K. DB - Scopus DO - 10.1016/j.epsc.2017.09.034 KW - Appendicitis Partial small bowel obstruction Play-dough M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 SP - 69-70 ST - Concurrent partial small bowel obstruction and acute appendicitis secondary to play-dough ingestion T2 - Journal of Pediatric Surgery Case Reports TI - Concurrent partial small bowel obstruction and acute appendicitis secondary to play-dough ingestion UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85034989782&doi=10.1016%2fj.epsc.2017.09.034&partnerID=40&md5=873aee357315751c9322623f0f149a98 VL - 29 ID - 1091 ER - TY - JOUR AB - A 35-year-old white male sustained head injuries in a motor vehicle accident. He underwent neurosurgical repair of a frontotemporal skull fracture and lacerated left frontal lobe; regenerated oxidized cellulose (Surgicel) was placed into the anterior cranial fossa for hemostasis. Forty-eight hours after surgery he suffered rapid deterioration of vision to no light perception from optic nerve compression. Radiologic and echographic evaluation demonstrated a subperiosteal soft tissue density in the orbital apex consistent with hematoma. At surgery for optic canal decompression, the cellulose hemostat was found in the apex of the left orbit, having migrated through orbital roof fractures, and had apparently caused the compressive optic neuropathy. Decompression resulted in return of vision to the level of counting fingers. AD - Dep. Ophthalmol., Univ. Iowa Hosp. Clin., Iowa City, IA 52242, United States AU - Dutton, J. J. AU - Tse, D. T. AU - Anderson, R. L. DB - Scopus IS - 6 M3 - Article N1 - Cited By :19 Export Date: 10 November 2020 PY - 1983 SP - 487-490 ST - Compressive optic neuropathy following use of intracranial oxidized cellulose hemostat T2 - Ophthalmic Surgery TI - Compressive optic neuropathy following use of intracranial oxidized cellulose hemostat UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0020956623&partnerID=40&md5=5a78ae70653d05d9c81340f03482c695 VL - 14 ID - 1758 ER - TY - JOUR AB - OBJECTIVE: Complications of penetrating craniocerebral injuries in war can be early (during the first week after wounding) or late (after that period). Postoperative hematomas, infections, seizures, and cerebrospinal fluid fistulas (CSFFs) are counted among the early complications, whereas foreign bodies migrating intracranially, seizures, infections, and posttraumatic hydrocephalus represent late complications. A total of 176 patients with well-defined head injuries from missiles, sustained during the Croatian Homeland War (1991-1995), developed a total of 61 (34.5%) complications. METHODS: A retrospective statistical analysis of the medical records of the patients in our series was performed to determine the risk factors for the onset of complications, which have unfavorable effects on outcomes. RESULTS: There were a total of 28 (15.9%) infections (deep or superficial), 21 (11.9%) cases of CSFFs, 9 (5.11%) cases of early epilepsy, and 3 cases of post-traumatic hydrocephalus. A total of 47.6% of patients with CSFFs developed intracranial infections. Of eight patients with meningoencephalitis, five had CSFFs and four had intracranially retained foreign bodies. Only one patient developed a cerebral abscess. Two patients died because of infectious complications (13.3%). Post-traumatic hydrocephalus (1.7%) required shunt placement. For 60% of patients with deep-seated intracranial infectious complications and 76% of patients with CSFFs, reoperations had to be performed, whereas this was the case for only 8% of patients without infections (chi2 = 43.6, p = 0.00001). CONCLUSIONS: Intracranially retained foreign bodies, wound age, wound site, and operations performed outside the neurosurgical services were the main risk factors for the development of complications. Complications themselves exerted a very unfavorable influence on outcomes. The development of complications reflects very reliably the neurosurgical technique applied. AD - Department of Neurosurgery, Clinical Hospital Split, Vjekoslava Spinéića 1, 21000 Split, Croatia. AN - 15974211 AU - Tudor, M. AU - Tudor, L. AU - Tudor, K. I. DA - May DO - 10.7205/milmed.170.5.422 DP - NLM ET - 2005/06/25 IS - 5 KW - Adult Cerebrospinal Fluid Croatia Debridement Epilepsy, Post-Traumatic/epidemiology Female Fistula/epidemiology Foreign Bodies/epidemiology Head Injuries, Penetrating/*complications/epidemiology/etiology Humans Hydrocephalus/epidemiology Male Meningoencephalitis/epidemiology Postoperative Complications/epidemiology Reoperation Retrospective Studies Risk Factors Time Factors Warfare Wound Infection/epidemiology LA - eng N1 - Tudor, Mario Tudor, Lorainne Tudor, Katarina Ivana Journal Article England Mil Med. 2005 May;170(5):422-6. doi: 10.7205/milmed.170.5.422. PY - 2005 SN - 0026-4075 (Print) 0026-4075 SP - 422-6 ST - Complications of missile craniocerebral injuries during the Croatian Homeland War T2 - Mil Med TI - Complications of missile craniocerebral injuries during the Croatian Homeland War VL - 170 ID - 54 ER - TY - JOUR AB - Major complications of foreign bodies in the esophagus carry significant morbidity and mortality risks. A retrospective case control study was performed to assess the factors associated with major complications. In total, 273 patients seen within a 7-year period were divided into 2 groups; 253 had no or minor complications, and 20 had major complications. Age, sex, duration of the foreign body, total white cell count (TWC), and nature and site of the foreign body were analyzed in the 2 groups. The major complication rate was 7.3%. Duration of the foreign body and TWC were the only statistically significant factors associated with major complications. Six patients required open neck exploration, 1 had an open thoracotomy, and 13 were treated by endoscopic removal. There were 2 deaths. Given the significant morbidity and mortality risks, we conclude that patients with a prolonged history of a foreign body in the esophagus and a raised TWC should be treated urgently. AD - Department of Otolaryngology, National University Hospital, Singapore. AN - 11077351 AU - Loh, K. S. AU - Tan, L. K. AU - Smith, J. D. AU - Yeoh, K. H. AU - Dong, F. DA - Nov DO - 10.1067/mhn.2000.110616 DP - NLM ET - 2000/11/15 IS - 5 KW - Adult Aged Aged, 80 and over Case-Control Studies Child, Preschool *Esophagus Female Foreign Bodies/*complications/surgery Humans Male Middle Aged Regression Analysis Risk Factors Time Factors LA - eng N1 - Loh, K S Tan, L K Smith, J D Yeoh, K H Dong, F Journal Article England Otolaryngol Head Neck Surg. 2000 Nov;123(5):613-6. doi: 10.1067/mhn.2000.110616. PY - 2000 SN - 0194-5998 (Print) 0194-5998 SP - 613-6 ST - Complications of foreign bodies in the esophagus T2 - Otolaryngol Head Neck Surg TI - Complications of foreign bodies in the esophagus VL - 123 ID - 33 ER - TY - JOUR AB - Endovascular treatment for aortic disease has emerged as an alternative mode of treatment that is particularly attractive for patients with severe comorbidities who would not be ideal candidates for open surgery. Although endoluminal interventions are minimally invasive, they are associated with complications, as are all surgical methods. The aim of this paper is to give an overview on thoracic aortic stent-graft complications with focus on failure modes and potential improvements. Procedure-Related Problems Successful thoracic aneurysm repair could be attained today in 98% to 100% of cases. Adverse events will occur after stent-graft placement in a minority of cases, and many of these complications can be diagnosed and managed with minimally invasive techniques. Access Vessel Issues Access related issues comprise a major reason for failure or conversion to open repair and can contribute to a significant amount of morbidity and mortality. Iliac artery trauma may occur when a stentgraft is forced through a small or tortuous iliac artery. Vascular trauma is especially likely in cases involving small, heavily or circumferentially calcified iliac arteries. Most iliac artery traumas may be treated with stents or stent-grafts, although surgical endarterectomy or bypass may also be required. Preoperative imaging is paramount to the success of endovascular procedures. Occasionally, challenging iliac or femoral anatomy may preclude access through these vessels and may need to gain direct access through the aorta or via the carotid or subclavian artery. Stent-Graft Misplacement Stent-graft misplacement may occur when: (a) the blood pressure is too high during deployment or balloon dilation of the stent-graft and caused a “wind sock” effect, particularly when proximal fixation is at or near the aortic arch. To avoid this problem, blood pressure must be lowered with vasodilator or beta-blocker drugs, or (b) the stent-graft is positioned across an angulated arterial segment, which may cause the introducer sheath to kink. Stent-graft misplacement can be prevented by using a more flexible stent-graft and by covering a longer segment in an angulated anatomic structure. Whenever insufficient lesion coverage results from stent-graft misplacement, a stent-graft extension should be put in place to adequately cover the landing zone. Accidental coverage of a branch vessel with the stentgraft is more difficult to manage. However, treatment may consist of positioning a bare stent so that it protrudes from within the origin of the covered vessel, thereby displacing the covering stent-graft membrane and restoring blood flow to the branch vessel. Aortic Perforation Aortic perforation may occur during stent-graft insertion and is easily recognized as a rapidly enlarging hematoma or hemothorax. Rapid covering of the perforation with a stent-graft is the first treatment option. Aortic perforation may also occur after stent-graft insertion due to erosion of the aortic wall by stent-graft struts. These perforations may be asymptomatic or may lead to aortic rupture or fistula formation. Endoleaks Type 1 endoleaks result from incomplete sealing of the stent-graft at the proximal or distal attachment site. They occur more frequently when: (a) the stent-graft landing zones are short, irregular, or ulcerated, (b) a suboptimal stent-graft diameter has been selected, or (c) the stent-graft is positioned across an angulated neck or in a narrow aortic arch and does not conform to the curved aortic contour. To maximize the neck length, we can use the distance between the origins of the left common carotid artery and left subclavian artery, occluding the LSA when necessary. In our experience, overstenting the left subclavian artery has not led so far to any particular complications. However, prior to doing so, we make sure that there is no right vertebral artery stenosis or absent vertebral collateral pathway. Secondary to obstruction of the LSA, if there is reduced perfusion of the left arm, surgical bypass can be performed electively in a second proce ure. Type 2 endoleaks result from persistent circulation in the aneurysm from a tributary to the aortic lumen excluded by the stent-graft. These endoleaks are less common in the region of the thoracic aorta than in the abdominal aortic region. In case of aortic diameter increase, selective embolisation by the collaterals or injection of thrombin by a direct puncture of the aorta can be proposed. Type 3 endoleaks arise from a defect of the stent-graft membrane itself or from the separation of components in modular stent-grafts. These endoleaks often result from stent-graft disconnection, which is more likely to occur when multiple stent-grafts with short overlapping areas are used. Type 1 and type 3 endoleaks may be treated with insertion of another stent-graft. Retrograde Dissection The most alarming complication is the retrograde type A dissection after implantation of the stent-graft. Bare springs of the stent-graft could perforate the medial layer of the aortic wall during the implantation in a very kinked arch but cases of secondary dissection were also described with other devices. For these reasons, some prefer not to use stent-grafts that are too rigid or with bare-springs. Also, ballooning for stent-graft apposition is one of the possible etiologic factors of intimal tear. In a recent European Registry on EVAR Complications, it was demonstrated that incidence of retrograde dissection was low (1.33%) and was associated with significant mortality (42%) (H. Eggebrecht et al., Circulation, 2009). Patients undergoing TEVAR for (acute) type B dissection appeared to be most prone for the occurrence of this complication which occurred during the index hospital ization as well as after discharge and during mid-term follow-up. Recently, many authors reported the late formation of new intimal tear resulting in pseudoaneurysm or dissection at the margin of the stent-graft. Many articles suggested that the causes of intimal tears were mechanical injury secondary to sharp stent tip, inflexibility of the stent-graft and the pulsatile forces in the aorta normally at curved portion of aorta where stent-graft and intima meet at an angle. If found, additional stent-graft placement must be performed for the management of these patients. To avoid these complications, many authors suggest covering longer portions of the descending aorta until it fits the parallel portion of the aortic wall or intima and the development of stent-grafts with smoother edges and more flexible bodies. Mortality Mortality is the most important criterion in appraising the results of TAA treatment. Conventional intervention carries a mortality rate that ranges between 3 and 26%, up to 75% for emergency repair. In a recent meta-analysis of thoracic stent grafts (Walsh S et al. JVS 2008), the thirty-day mortality was 5.57% in elective situation versus 16% in emergency. Post Implantation Syndrome The incidence of transient post-implantation syndrome (fever, leukocytosis and elevated C-reactive protein) is known to be 20 to 60%. The syndrome is suggested to be a nonspecific systemic inflammatory reaction rather than a true infection. Patients usually recover with conservative treatments in 2 to 10 days. Pleural effusion and platelet count drop are frequent but mysterious complications of stent-graft in aortic dissection. It could originate from foreign body irritation to the adjacent pleura. It usually resolves spontaneously within 3 months after the intervention. The platelet count drop is observed in 1/3 of cases 1 to 3 days after stent-graft insertion. It returned to initial base line values in 5 to 10 days without transfusion or any other treatment. Because all cases of platelet count drop occurred in patients whose former patent false lumen had been obliterated by thrombus formation, consumptive coagulopathy is suggested to be the cause of this transient complication. Paraplegia and Cerebrovascular Accidents Although no randomized trials have been conducted comparing stent-graft placement with surgery for thoracic aortic disease, paraplegia seems less likely with stent-graft placement than with surgery. Paraplegia is crucially influenced by the duration of aortic clamping in the open thoracic aortic operation. Despite many improvements in the technique, the rates of paralysis in conventional open surgery range from 1.5 to 19% in high-volume centers. Absence of thoracotomy and cross-clamping of the aorta are the main advantages of endovascular repair. However, since a large number of intercostal arteries are acutely occluded, especially when long stent-grafts are implanted, paralysis can still occur. In the largest meta-analysis of endovascular TAA repairs reported, the rate of paraplegia is 5.4% (Walsh S et al. JVS 2008). This complication seems to be significantly more frequent in patients undergoing concurrent AAA repair or who had undergone AAA repair earlier. Successful treatment of stent-graft-induced paralysis with drainage of cerebrospinal fluid has been reported. The neurological complications are less frequent in case of dissection (0.8% of paraplegia and 1.9% of stroke in the meta-analysis of H. Eggebrecht et al., Eur Heart J 2006) Strokes are caused by the manipulation of wires and catheters in an atherosclerotic aortic arch. The incidence of this complication is actually now lower with the new endografts. To keep the embolic risk low, the tip of the delivery system should be as short and flexible as possible, no manipulation on artificial aortic valves should be done where clots could be present and good anticoagulation is mandatory. AD - H. Rousseau, Dept. of Radiology, CHU Rangueil, Toulouse, France AU - Rousseau, H. AU - Chabbert, V. AU - Marcheix, B. DB - Embase DO - 10.1007/s00270-010-9954-3 KW - vasodilator agent beta adrenergic receptor blocking agent thrombin C reactive protein Europe prevention society stent dissection mortality patient aorta paraplegia perforation surgery implantation iliac artery platelet count lacrimal fluid paralysis aortic wall subclavian artery aortic arch meta analysis cerebrovascular accident intima membrane neck aortic disease artery injury emergency blood pressure aneurysm anticoagulation morbidity endarterectomy minimally invasive procedure carotid artery blood flow hematoma hematothorax imaging fistula common carotid artery vertebral artery stenosis obstruction perfusion arm thoracic aorta artificial embolization injection puncture devices etiology register hospital aortic rupture false aneurysm injury descending aorta fever leukocytosis inflammation infection conservative treatment pleura effusion aortic dissection foreign body pleura transfusion patent blood clotting disseminated intravascular clotting aortic clamping thoracotomy artery cerebrospinal fluid follow up neurological complication heart catheter risk aortic valve blood vessel injury LA - English M3 - Conference Abstract N1 - L70288723 2010-11-02 PY - 2010 SN - 0174-1551 SP - 85-87 ST - Complications of endografting: Prevention and management T2 - CardioVascular and Interventional Radiology TI - Complications of endografting: Prevention and management UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70288723&from=export http://dx.doi.org/10.1007/s00270-010-9954-3 VL - 33 ID - 560 ER - TY - JOUR AB - A symptom of prolonged conflict is the destruction of infrastructure and healthcare systems. While the need for acute trauma services is obvious in conflict zones, patients with chronic diseases also require care. This report describes the clinical course of a young teenage girl with a large mid pelvic tumour originating from the left ovary and reaching the umbilicus. She presented with acute abdominal pain and underwent surgery in a healthcare facility within a conflict zone. She was then transferred to a neighbouring country for continuing care. The tumour is malignant. After further surgery, she required chemotherapy and will need ongoing surveillance. She has since returned to her home country. It is doubtful that she will be able to access all the care she needs. We describe her healthcare needs and discuss the disastrous effects of conflict on meeting the health needs of civilian populations in war zones. © 2017 BMJ Publishing Group. All rights reserved. AD - Ziv Medical Center, Tzfat, Israel Faculty of Medicine in the Galilee, Bar Ilan University, Israel AU - Hayari, L. AU - On, E. S. AU - Fedorenko, A. AU - Sergio, S. AU - Zidan, J. AU - Solomonov, E. C7 - bcr-2016-217787 DB - Scopus DO - 10.1136/bcr-2016-217787 M3 - Article N1 - Export Date: 10 November 2020 PY - 2017 ST - Complications of dysgerminoma: Meeting the health needs of patients in conflict zones T2 - BMJ Case Reports TI - Complications of dysgerminoma: Meeting the health needs of patients in conflict zones UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011017779&doi=10.1136%2fbcr-2016-217787&partnerID=40&md5=9697a28c4edc5f66960c6713174f88e1 VL - 2017 ID - 1158 ER - TY - JOUR AB - PURPOSE: To describe the clinical and histopathologic features of intractable secondary glaucoma induced by AlphaCor keratoprosthesis. METHODS: An elderly woman with pseudoexfoliation glaucoma and pseudophakic bullous keratopathy in the right eye had graft failures after penetrating keratoplasty. Her best-corrected visual acuity at presentation was counting fingers in the right eye and 20/30 in the left eye. Examination showed severe corneal neovascularization. Chirila keratoprosthesis type II was implanted in 2 stages. Ten months later, the patient developed dense retrocorneal membrane, 360 degrees occlusion of angles, intractable glaucoma, no light perception, and nasal stromal melting associated with partial extrusion of the keratoprosthesis. RESULTS: Histopathology revealed invasion of the porous material of the keratoprosthesis by reactive fibroblasts and multinucleated foreign-body giant cells. In the area of dehiscence, we noted thinning and lysis of the collagen fibers, infiltration of lymphocytes, and plasma cells with a sheet of fibroinflammatory tissue extending into the anterior chamber. CONCLUSIONS: Corneal stromal melting and retrocorneal prosthetic membrane formation after AlphaCor keratoprosthesis implantation led to intractable glaucoma and extrusion of the implant. AD - Department of Ophthalmology, University of Florida College of Medicine, Jacksonville, FL 32209, USA. kvchalam@jax.ufl.edu AN - 18043186 AU - Chalam, K. V. AU - Chokshi, A. AU - Agarwal, S. AU - Edward, D. P. DA - Dec DO - 10.1097/ICO.0b013e31813e0bd8 DP - NLM ET - 2007/11/29 IS - 10 KW - Aged, 80 and over Artificial Organs/*adverse effects *Cornea Corneal Diseases/*etiology Corneal Stroma/pathology Device Removal Female Fibroblasts/pathology Foreign-Body Migration/etiology Foreign-Body Reaction/pathology Giant Cells/pathology Glaucoma/*etiology Humans Intraocular Pressure Prostheses and Implants/*adverse effects Visual Acuity LA - eng N1 - Chalam, Kakarla V Chokshi, Amit Agarwal, Swati Edward, Deepak P Case Reports Journal Article United States Cornea. 2007 Dec;26(10):1258-60. doi: 10.1097/ICO.0b013e31813e0bd8. PY - 2007 SN - 0277-3740 (Print) 0277-3740 SP - 1258-60 ST - Complications of AlphaCor keratoprosthesis: a clinicopathologic report T2 - Cornea TI - Complications of AlphaCor keratoprosthesis: a clinicopathologic report VL - 26 ID - 71 ER - TY - JOUR AB - We determined the incidence of acute, major complications in a population of 28,395 patients who underwent lumbar laminectomy for discogenic radiculopathy in the United States in 1980. This population was drawn from a broad cross-section of community hospitals and represented 31% of all patients who underwent laminectomy that year for this condition. Our cohort excluded patients with a) operations exceeding two disc levels, b) fusion, c) previous lumbar laminectomy, or d) coexistent discitis, spondylosis, spinal stenosis, myelopathy, or arachnoiditis. The incidence of death was 5.9 per 10,000. The causes of death were septicemia, myocardial infarction, and pulmonary emobolus. The incidence of at least one major complication was 157 per 10,000. The incidences of specific complications were as follows: infection requiring intravenously administered antibiotics, 30.7; major neurological deficit, 29.8; pulmonary embolus, 10.7; and myocardial infarction, 5.6. We studied four additional categories of complication. Patients were counted only when a second operation was required to treat the complication. The categories and incidence per 10,000 were as follows: incisional hematoma, 8.7; cerebrospinal fluid fistula, 10.5; ventral perforation, 1.6; and retention of a foreign body, 0.7. Among the patients whose hospitalizations were otherwise normal, 6.7% received a blood transfusion; of the patients whose hospitalizations were complicated, 24% required transfusion. The demographic characteristics of transfusion. The demographic characteristics of patients with a normal hospitalization were tabulated separately from those whose hospitalizations were complicated. Neurosurgeons performed 60% of the operations, and orthopedic surgeons performed 40%. The speciality of the surgeon was not a factor in determining the risk involved in surgery. Spinal anesthesia was used in 7% of the cases, and no pattern of complications emerged that was uniquely related to that technique. AD - Department of Neurosurgery, University of Wisconsin, Madison. AN - 2770987 AU - Ramirez, L. F. AU - Thisted, R. DA - Aug DO - 10.1097/00006123-198908000-00012 DP - NLM ET - 1989/08/01 IS - 2 KW - Demography Hospitals, Community Humans Intervertebral Disc/*surgery Intraoperative Complications/epidemiology/mortality Lumbosacral Region Postoperative Complications/epidemiology/mortality United States LA - eng N1 - Ramirez, L F Thisted, R Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. United States Neurosurgery. 1989 Aug;25(2):226-30; discussion 230-1. doi: 10.1097/00006123-198908000-00012. PY - 1989 SN - 0148-396X (Print) 0148-396x SP - 226-30; discussion 230-1 ST - Complications and demographic characteristics of patients undergoing lumbar discectomy in community hospitals T2 - Neurosurgery TI - Complications and demographic characteristics of patients undergoing lumbar discectomy in community hospitals VL - 25 ID - 18 ER - TY - JOUR AB - Background: Inadequately reprocessed reusable surgical instruments (RSIs) may harbour infectious agents which may then be transferred to a suitable site for replication. Aim: To determine the cumulative effect of 20 cycles of contamination, cleaning (manual or manual followed by automated) and steam sterilization on high-complex-design RSIs used for orthopaedic surgery. Methods: New flexible medullary reamers and depth gauges were contaminated by soaking in tryptone soya broth, containing 5% sheep blood and 109 cfu/mL of Staphylococcus aureus (ATCC 25923), for 5 min. To mimic a worse-case scenario, RSIs were dried 7 h and subjected to either (a) rinsing in distilled water, (b) manual cleaning or (c) manual plus automated cleaning (reference standard), and steam sterilization. The contamination, cleaning, and sterilization cycle was repeated 20 times. Adenosine triphosphate (ATP) was measured after cleaning procedures; microbial load and residual protein were measured following the 10th and 20th reprocessing, in triplicate. Scanning electron microscopy (SEM) was used to confirm soil and biofilm presence on the RSIs after the 20th reprocessing. Findings: Manual and manual plus automated cleaning significantly reduced the amount of ATP and protein residues for all RSIs. Viable bacteria were not detected following sterilization. However, SEM detected soil after automated cleaning, and soil, including biofilms, after manual cleaning. Conclusion: Soil and/or biofilms were evident on complex-design RSIs following 20 cycles of contamination and reprocessing, even using the reference standard method of cleaning. Although the depth gauges could be disassembled, biological residues and biofilm accumulated in its lumen. The current design of these RSIs prevents removal of all biological soil and this may have an adverse effect on patient outcome. © 2018 The Healthcare Infection Society AD - Faculty of Nursing, Federal University of Goiás, Goiânia, Brazil Surgical Infection Research Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil Macquarie University Hospital, Macquarie University, Sydney, Australia AU - Lopes, L. K. O. AU - Costa, D. M. AU - Tipple, A. F. V. AU - Watanabe, E. AU - Castillo, R. B. AU - Hu, H. AU - Deva, A. K. AU - Vickery, K. DB - Scopus DO - 10.1016/j.jhin.2018.11.001 IS - 1 KW - Biofilm Cleaning Colony count Microbial Sterilization Surgical instrument M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2019 SP - e53-e60 ST - Complex design of surgical instruments as barrier for cleaning effectiveness, favouring biofilm formation T2 - Journal of Hospital Infection TI - Complex design of surgical instruments as barrier for cleaning effectiveness, favouring biofilm formation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85057734096&doi=10.1016%2fj.jhin.2018.11.001&partnerID=40&md5=daa542e3987d22f3e66dfa0bd01ffb91 VL - 103 ID - 1001 ER - TY - JOUR AB - Rationale: Intraluminal migration of a retained surgical sponge causing intestinal obstruction and fistula is extremely rare occurrence. Patient concerns: A case of a 35-year-old male, who complaining a diffuse abdominal pain beginning three days earlier. He also complained of occasional vomiting, nonspecific abdominal pain, and an unintentional 15 kg weight loss during the past 2 years. However, there were no clear findings in previous laboratory work. He had received an open appendectomy approximately 4 years earlier. Diagnoses: Retained surgical sponge. Interventions: A contrast-enhanced CT of the abdomen showed a clear invagination of the small intestine. However, intraoperatively, we could not find an intestinal segment with intussusception. After the adhesive intestine was detached, a jejunal-ileal cross-linked fistula was found. More surprisingly, a retained surgical sponge was found inside the ileal fistula when the cross-linked fistula was detached. Outcomes: The patient was discharged 7 days after surgery. Lessons: This is the first report showing an atypical image of a complete transmural migration of a retained surgical sponge mimicking intussusception. © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. AD - Department of General Surgery, Suzhou Municipal Hospital, Suzhou, 225001, China Department of Gastrointestinal Surgery, Clinical Medical College of Yangzhou University, Northern Jiangsu People's Hospital, Yangzhou, China Medical Research Center, Clinical Medical College of Yangzhou University, Northern Jiangsu People's Hospital, Yangzhou, Jiangsu Province, China AU - Zhou, Y. AU - Chen, P. AU - Qiao, T. AU - Chen, Y. F. AU - Zong, L. C7 - e8246 DB - Scopus DO - 10.1097/MD.0000000000008246 IS - 42 KW - abdomen intussusception retained surgical sponge transmural migration M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2017 ST - Complete transmural migration of a retained surgical sponge: An atypical case in image mimicking intussusception T2 - Medicine (United States) TI - Complete transmural migration of a retained surgical sponge: An atypical case in image mimicking intussusception UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85032491603&doi=10.1097%2fMD.0000000000008246&partnerID=40&md5=c55f90ac8e38b0e3cb8807eec9d9ef86 VL - 96 ID - 1118 ER - TY - JOUR AB - Background: Retained foreign bodies after surgery constitute an occasional misadventure in modern surgery and cause returns to the operating room. Approximately, two-thirds of retained objects are sponges. Methods: We report on a 10-year-old boy presenting with a retained surgical sponge that had migrated completely into the lumen of the ileum. Removal was performed by laparotomy and ileotomy. Radiological and intraoperative findings are discussed, and a review of the recent relevant literature is provided. Results: Laparotomy revealed an intraluminal 30 cm long lap sponge (25 cm in the ileum and 5 cm in the cecum) which had completely migrated into the interior of the intestine. Complications, i.e., adhesion bands and fistulae, were treated subsequently. Conclusions: The case highlights the importance of a careful count of sponges before and after surgery and thorough exploration of all quadrants of the abdomen at the termination of surgical cases. © Springer-Verlag 2005. AD - S. Assari, No 9/a. Maasoomi st., Tehran, Iran AU - Moosavi Naeeni, S. M. AU - Panahi, F. AU - Assari, S. DB - Embase DO - 10.1007/s10353-005-0177-9 IS - 5 KW - abdomen adhesion appendectomy article case report cecum fistula foreign body human ileum intestine laparotomy male radiodiagnosis school child LA - English M3 - Article N1 - L41711999 2006-01-03 PY - 2005 SN - 1682-1769 SP - 321-324 ST - Complete intraluminal migration of a retained surgical lap sponge 4 years after appendicectomy: A case report T2 - European Surgery - Acta Chirurgica Austriaca TI - Complete intraluminal migration of a retained surgical lap sponge 4 years after appendicectomy: A case report UR - https://www.embase.com/search/results?subaction=viewrecord&id=L41711999&from=export http://dx.doi.org/10.1007/s10353-005-0177-9 VL - 37 ID - 625 ER - TY - JOUR AB - Three methods are currently available to reconstitute hair follicles in mice. Direct comparisons have yet to be made to determine which method is most efficient. In this study, mouse epithelial cells (MECs) and mouse dermal cells (MDCs) were grafted onto the dorsal skin of nude mice using the chamber, flap or patch assays. Comparisons were made based on gross, scanning electron microscopic and histological observations. MDCs alone induced hair follicle reconstitution with the production of hairs yielding false-positive results caused by contamination by hair follicle remnants. Neither primary MECs nor cultured MDCs alone formed hair follicles but did result in hair follicle formation when mixed together. Frozen MECs or MDCs resulted in decreased hair follicle-inductive activity but could still regenerate hairs. The hair patch assay was the quickest model (20±3days) to determine whether cell mixtures would reconstitute hair follicles that produce hairs; however, the hair follicles were randomly orientated and often associated with foreign body granulomas. The flap assay took the longest time (29±2days) to produce follicles and hairs to develop with a clinically natural appearance, but an epidermal sheet was needed. The chamber assay was the most labour-intensive and cell number-dependent procedure but follicles developed in a dense, clinically normal manner. © 2011 John Wiley & Sons A/S. AD - The Jackson Laboratory, Bar Harbor, ME, United States AU - Liang, Y. AU - Silva, K. A. AU - Kennedy, V. AU - Sundberg, J. P. DB - Scopus DO - 10.1111/j.1600-0625.2011.01366.x IS - 12 KW - Chamber Flap Hair follicle Patch Reconstitution M3 - Article N1 - Cited By :17 Export Date: 10 November 2020 PY - 2011 SP - 1011-1015 ST - Comparisons of mouse models for hair follicle reconstitution T2 - Experimental Dermatology TI - Comparisons of mouse models for hair follicle reconstitution UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-81455158744&doi=10.1111%2fj.1600-0625.2011.01366.x&partnerID=40&md5=1f1a57e1f07497ef831b28fdfbf9aab5 VL - 20 ID - 1401 ER - TY - JOUR AB - Aim: This study compared, histometrically, the alveolar bone healing after grafting rats extraction socket with particles of organic or inorganic bovine bone. Method: The volume fraction of grafted materials and bone trabeculae was estimated in histologic images at the end of the 2nd and 9th weeks post-operatively by a differential point-counting method. Results: Particles of both materials were observed partially filling the cervical alveolar third and the volume fraction of inorganic graft was larger than that of organic graft 2 and 9 weeks following implantation. Although evoking neither a foreign body reaction nor a persisting inflammatory response, both materials delayed bone healing. By the 2nd week, the delay was more pronounced in the animals grafted with inorganic than in those grafted with organic bone, but only in the animals whose inorganic graft occupied more than 50% of the cervical third. By the 9th week, despite the greater volume fraction of inorganic graft the percent of bone healing was similar to that observed in the animals grafted with organic bone. Conclusion: The degree of impairment of bone healing resulted from combination of factors such as type of material, its relative amount and the phase of the reparational process. AD - Department of Morphology Stomatology and Physiology, University of São Paulo, Av. do Café S/N, 14040-904 Ribeirão Preto SP, Brazil Dental School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil AU - Calixto, R. F. E. AU - Teófilo, J. M. AU - Brentegani, L. G. AU - Lamano, T. DB - Scopus IS - 24 KW - Alveolar healing Inorganic bovine bone graft Organic bovine bone graft M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2008 SP - 1512-1519 ST - Comparison of rat bone healing following intra-alveolar grafting with organic or inorganic bovine bone particles T2 - Brazilian Journal of Oral Sciences TI - Comparison of rat bone healing following intra-alveolar grafting with organic or inorganic bovine bone particles UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-48249130864&partnerID=40&md5=a8b3f7197c97e736405c226897d62c58 VL - 7 ID - 1544 ER - TY - JOUR AB - INTRODUCTION: Clinically, vaginal packing provides the benefit of hemostasis and is designed to prevent the formation of postoperative hematomas. Despite the common use of vaginal packing in pelvic surgery, there is limited data to indicate which material has the ideal characteristics for vaginal packing. MATERIALS AND METHODS: Three packing materials were used: DeRoyal® Fluftex™ (DeRoyal Industries, Inc., Powell, Tennessee), NHP Surgi-Pak™ vaginal packing (NHP Industries, Inc., City of Industry, California), and Curad® Plain Packing Strips (Medline Industries, Inc., Northfield, Illinois). A fluid with similar viscosity to human blood, defibrinated sheep's blood (Remel Laboratories, Nenexa Kansas) was used to saturate the materials. The primary outcome was the amount of fluid absorbance of each product in both the handpacked and unpacked state. The number of drops used to saturate each material were counted and converted to mL/g. Each product was tested three times and the results were measured by counting the number of drops needed to saturate the material in each experiment. Experiment: Three materials were obtained and conducted into two different experiments to test absorbance. The packed trial consisted of 0.1g of material and was compacted in a 146mm standard Pasteur pipette (Sigma-Aldrich Corp., St. Louis, Missouri). Droplets of sheep's blood were dispensed until each material had reached its capacity, which was determined by counting the last sequential drop received onto the respective material before the first of the fluid fell from the material into the collecting container. Trials were conducted three times per material and an average of the three trials was calculated. The second experiment tested 1g of each material unpacked and folded into eight layers. Droplets of blood were placed onto the material until each material leaked, which was defined again as the first fluid to fall from the material into the collecting container that it was suspended above. The number of drops needed to produce this effect was recorded. All droplets were counted and converted to mL/g. Standard deviation was calculated for each material in both experiments and an analysis of variance (ANOVA) single factor test was done. RESULTS: Three trials were conducted per material and there was a difference in absorbance between each packing material (p=0.02 packed, p=0.001 unpacked). Additionally, the plain packing strip absorbed the least amount of blood product in the packed and unpacked state compared to DeRoyal® Fluftex™ and NHP Surgi-Pak™ vaginal packing. The average absorbance of the packed materials was 7.7mL/g for DeRoyal® Fluftex™, 9.8mL/g for NHP Surgi-Pak™ vaginal packing, and 7.5mL/g for the Curad® Plain Packing Strips. There was a standard deviation of 2.08 drops for DeRoyal® Fluftex™, 3.51 drops for NHP Surgi-Pak™ vaginal packing, and 1.73 drops for Curad® Plain Packing Strips. Absorbance for DeRoyal® Fluftex™ unpacked was 8.2mL/g, NHP Surgi-Pak™ vaginal packing unpacked was 7.00mL/g, and Curad® Plain Packing Strips was 4.8mL/g. The standard deviation for the unpacked experiment was 29.02 drops for DeRoyal® Fluftex™, 13.61 drops for NHP Surgi-Pak™ vaginal packing, and 15.59 drops for Curad® Plain Packing Strips. A p-value of less than .05 in a confidence interval of 95% was determined. CONCLUSION: Even though there are studies showing the clinical benefits of vaginal packing after a variety of gynecological surgeries, there is less known about the characteristics of the ideal material. Minimal foreign body reaction, decreased adherence to surgical scars, X-ray visualization, low cost, and easy availability are among the ideal characteristics of the presumed ideal material used for vaginal packing. In this study, we compared the absorbance between three commonly used materials and did not find any statistical differences. Further studies are needed to show the clinical benefits and mechanical characteristics of material used for vaginal packing. Due to the lack of a statistically significant difference in absorbance between the materials, evaluation of mechanical characteristics may be beneficial in determining an ideal vaginal packing product. AD - University of Arizona, Phoenix, Arizona, Star Urogynecology, Peoria, Arizona. Arizona State University, Tempe, Arizona. Department of Minimally Invasive Surgery, The Marchand Institute for Minimally Invasive Surgery, Mesa, Arizona. Department of Obstetrics and Gynecology,UCLA School of Medicine, Los Angeles, California. AN - 32243561 AU - Azadi, A. AU - Pinhasov, K. AU - Ware, K. AU - Marchand, G. J. AU - Ostergard, D. R. DA - May 28 DP - NLM ET - 2020/04/04 KW - Animals Bandages California Female Humans Sheep *Vagina LA - eng N1 - Azadi, Ali Pinhasov, Karin Ware, Kelly Marchand, Greg J Ostergard, Donald R Comparative Study Journal Article United States Surg Technol Int. 2020 May 28;36:186-190. PY - 2020 SN - 1090-3941 (Print) 1090-3941 SP - 186-190 ST - Comparison of Mechanical Characteristics of Commonly Used Vaginal Packing Materials T2 - Surg Technol Int TI - Comparison of Mechanical Characteristics of Commonly Used Vaginal Packing Materials VL - 36 ID - 246 ER - TY - JOUR AD - Department of Plastic Surgery, Ga-Rankuwa Hospital, Pretoria, South Africa AU - van Heerden, J. DB - Scopus IS - 12 I M3 - Article N1 - Cited By :11 Export Date: 10 November 2020 PY - 2005 SP - 972-974 ST - Comparison of inflammatory response to polyglytone 6211 and polyglecaprone 25 in a rat model T2 - South African Medical Journal TI - Comparison of inflammatory response to polyglytone 6211 and polyglecaprone 25 in a rat model UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-29644448143&partnerID=40&md5=8dd8ab739b122f770a4e027a274b2bc1 VL - 95 ID - 1594 ER - TY - JOUR AB - Mechanical stapling of the vaginal cuff during hysterectomy has been proposed as a way to minimize bacterial contamination, thereby reducing infectious morbidity and hospital stay. Twenty-four pathogen-free New Zealand white rabbits underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy using either chromic suture or copolymer staple to close the vaginal cuff. Aerobic and anaerobic cultures were obtained from the peritoneal cavity upon entering, and from the vaginal cuff during the initial operation and on postoperative day 3 or 8. When compared with chromic suture, stapling of the vaginal cuff during hysterectomy did not result in significant reduction of postoperative bacteria isolated from the vaginal cuff or peritoneal cavity. In addition, copolymer staples were associated with histologic evidence of more extensive necrosis and cellular exudate while significantly increasing adhesion formation between the vaginal apex and surrounding viscera. Stapling the vaginal cuff does not significantly reduce bacterial count after hysterectomy, significantly increases adhesion formation, and may interfere with normal wound healing in an animal model. AD - From the Departments of Obstetrics and Gynecology and Pathology, The University of Michigan, Ann Arbor, Michigan. Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor AN - 114771485. Language: English. Entry Date: 20190825. Revision Date: 20190825. Publication Type: journal article AU - McNeeley Jr, S. Gene AU - Elkins, Thomas E. AU - Portz, Douglas M. AU - Warren, Jeffrey AU - Delancey, John O. L. AU - McNeeley, S. G., Jr. AU - Elkins, T. E. AU - Portz, D. M. AU - Warren, J. AU - DeLancey, J. O. DB - ccm DP - EBSCOhost IS - 6 KW - Surgical Instruments -- Adverse Effects Sutures -- Adverse Effects Hysterectomy Peritoneum -- Pathology Peritoneum -- Microbiology Vagina -- Pathology Rabbits Animal Studies Vagina -- Surgery Wound Healing Vagina -- Microbiology Female Adhesions Bacteria Validation Studies Comparative Studies Evaluation Research Multicenter Studies N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0401101. PMID: NLM3186094. PY - 1988 SN - 0029-7844 SP - 862-865 ST - Comparison of copolymer staple versus chromic suture during hysterectomy: gross, histologic, and microbiologic findings T2 - Obstetrics & Gynecology TI - Comparison of copolymer staple versus chromic suture during hysterectomy: gross, histologic, and microbiologic findings UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=114771485&site=ehost-live&scope=site VL - 72 ID - 907 ER - TY - JOUR AB - Purpose: Comparison of the inflammatory reaction promoted by textured silicone implants and that caused by the implant bonded with e-ptfe. Methods: One-hundred and fifty rats were divided into three equal groups (control, silicone, and bonded e-ptfe). These groups were subdivided into five groups, according to the second operation, i.e., 7,30,60,90 and 180 days. Histology of the peri-implant tissue was analyzed by morphometry with blood count (neutrophilos, lymphocytes, macrophages, fibroblasts and capillaries). Results: Comparison of subgroups 7,30,60,90, 180 days: - neutrophils: silicone: > in subgroup 7 days; bonded e-ptfe: > in subgroups 7 and 30 days; - lymphocytes: silicone: > in subgroup 7 and 180 days; bonded e-ptfe: > in subgroup 180 days; - macrophages: silicone: > in subgroup 7 and 60 days; bonded e-ptfe: > in subgroup 7,30 and 60 days; - fibroblasts: silicone: > in subgroup 30 and 60 days;- vascular volume: silicone: in subgroup 7, 60 and 90 days; bonded e-ptfe: > in subgroup 7 days. Comparison of groups: neutrophils : 7 days: > in silicone and bonded e-ptfe; 30 days: > in bonded e-ptfe; - lymphocytes:- 7,30,90 and 180 days: in the control; macrophages:- 7,30 and 60 days: > in silicone & bonded e-ptfe; 180 days > in silicone; fibroblasts: - 7,30 and 90 days: > in silicone and bonded e-ptfe; 180 days: > in bonded e-ptfe; vascular volume - 7,60,90 and 180 days: > in silicone and bonded e-ptfe; 30 days: > in bonded e-ptfe. Conclusions: The acute stage of the inflammatory response was more severe and irregular in the silicone implant; both the silicone implant and the silicone bonded with e-ptfe promoted chronic inflammatory reaction and weak foreign body inflammatory response. These reactions were greater in the silicone implant group. AD - Division of Plastic Surgery, UNISA, São Paulo, Brazil Division of Pathology, School of Medicine of ABC, Santo André, Brazil Division of Plastic Surgery, Department of Surgery, USP, Brazil Rua Bom Pastor, 1238, 04203-001 São Paulo - SP, Brazil AU - Haddad Filho, D. AU - Zveibel, D. K. AU - Alonso, N. AU - Gemperli, R. DB - Scopus DO - 10.1590/s0102-86502007000300006 IS - 3 KW - Polytetrafluoroethylene Rats, wistar Silicone elastomers Silicone gels M3 - Article N1 - Cited By :8 Export Date: 10 November 2020 PY - 2007 SP - 187-194 ST - Comparison between textured silicone implants and those bonded with expanded polytetrafluoroethylene in rats T2 - Acta Cirurgica Brasileira TI - Comparison between textured silicone implants and those bonded with expanded polytetrafluoroethylene in rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-34250222079&doi=10.1590%2fs0102-86502007000300006&partnerID=40&md5=ad473ccbcb45d0f665907990df0d3d84 VL - 22 ID - 1571 ER - TY - JOUR AB - OBJECTIVE: To investigate and compare the attitudes of operating room nurses and doctors regarding patient safety, performance of surgical time-out and recognition of count error. METHODS: This cross-sectional study recruited operating room nurses, surgeons and anaesthesiologists between 1 August 2015 and 5 February 2016. A Safety Attitude Questionnaire was used to analyse the three elements in both groups of operating room staff (nurses and doctors). RESULTS: The study analysed the questionnaires from 171 participants; 95 nurses (55.6%) and 76 doctors (44.4%). Differences exist between doctors and nurses regarding teamwork climate, working conditions, perception of management and the recognition of stress. On the performance of surgical time-out, nurses showed higher scores on way of counting, while doctors showed higher scores on the time-out procedure itself. Also, doctors believed they actively cooperated with the nurses, while nurses believed they did not receive cooperation. Scores for the recognition of count error were higher in nurses than in doctors. More experienced operating room staff showed higher scores than younger less experienced staff. CONCLUSIONS: Perceptual differences among doctors and nurses need to be minimized for the safety of the patient in the operating room. AD - Department of Nursing, Seoul National University Cancer Hospital, Seoul, Republic of Korea. Korea University Graduate School of Public Health, Seoul, Republic of Korea. Department of Process Innovation Team, Seoul National University Hospital, Seoul, Republic of Korea. Department of Nursing, Operating Room of Seoul National University Hospital, Seoul, Republic of Korea. Department of Nursing, Operating Room of Seoul National University Children's Hospital, Seoul, Republic of Korea. AN - 31880182 AU - Kwon, E. AU - Kim, Y. W. AU - Kim, S. W. AU - Jeon, S. AU - Lee, E. AU - Kang, H. Y. AU - Nam, S. AU - Kim, M. DA - Apr DO - 10.1177/0300060519884501 DP - NLM ET - 2019/12/28 IS - 4 KW - Surgical safety nurse operating rooms retained surgical items surgical time-out LA - eng N1 - 1473-2300 Kwon, Eunok Orcid: 0000-0003-3449-3395 Kim, Young Woo Kim, Seo Won Jeon, Sujeong Lee, Eunsook Kang, Hye-Young Nam, Seungnam Kim, Mihyeong Journal Article England J Int Med Res. 2020 Apr;48(4):300060519884501. doi: 10.1177/0300060519884501. Epub 2019 Dec 27. PY - 2020 SN - 0300-0605 SP - 300060519884501 ST - A comparative study on patient safety attitude between nurses and doctors in operating rooms T2 - J Int Med Res TI - A comparative study on patient safety attitude between nurses and doctors in operating rooms VL - 48 ID - 237 ER - TY - JOUR AB - Purpose: In this manuscript, the authors describe an animal study comparing shrinkage, inflammatory response and fibroplasia in heavyweight (HW-PP) and lightweight polypropylene (LW-PP) meshes. Methods: Both meshes were fixed on abdominal fascia of 25 Wistar rats (epifascial onlay placement). They were killed at 7, 28 and 90 days to measure the prostheses. Histological analysis was performed with hematoxylin-eosin for cellular counting and immunohistochemistry to measure collagen types I and III. Results: The authors found that the LW-PP mesh presented greater median shrinkage than HW-PP mesh at 7 (P =.036), 28 (P =.674) and 90 days (P =.038) postoperatively. There were more neutrophils on LW-PP mesh (P =.008) at 7 days, gradually diminishing in both prostheses. Lymphocytes were similar between the implants at 7 days, diminishing about 50 % on LW-PP mesh (P <.001) at 90 days. Macrophages and giant cells diminished on LW-PP and increased on HW-PP meshes (P <.001). Collagen I/III ratio presented a progressive, almost fivefold rise at 90 days, on both mesh types (P <.001). The collagen I/III ratio was similar between LW-PP and HW-PP meshes at the three times studied. Conclusions: It is concluded that LW-PP showed more shrinkage than HW-PP mesh at 7 and 90 days, despite the fact that HW-PP presented more lately foreign body reaction. The collagen I/III ratio was similar between the prostheses and increased during the postimplant period. © 2013 Springer-Verlag France. AD - Programa de Pós-Graduação em Cirurgia, Universidade Federal Do Rio Grande Do sul (UFRGS), Ramiro Barcelos Street 2400, 90035-003 Porto Alegre, RS, Brazil Faculdade de Medicina (FAMED), Universidade Federal Do Rio Grande (FURG), Rio Grande, RS, Brazil AU - Zogbi, L. AU - Trindade, E. N. AU - Trindade, M. R. M. DB - Scopus DO - 10.1007/s10029-013-1046-2 IS - 6 KW - Abdominal wall Animal experimentation Collagen Hernia Shrinkage Surgical mesh M3 - Article N1 - Cited By :24 Export Date: 10 November 2020 PY - 2013 SP - 765-772 ST - Comparative study of shrinkage, inflammatory response and fibroplasia in heavyweight and lightweight meshes T2 - Hernia TI - Comparative study of shrinkage, inflammatory response and fibroplasia in heavyweight and lightweight meshes UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84890568867&doi=10.1007%2fs10029-013-1046-2&partnerID=40&md5=55114ad714a6281ea84dbbbd8f63ee3e VL - 17 ID - 1304 ER - TY - JOUR AB - Hemostatic agents are broadly utilized across the surgical specialties. While specific characteristics desirable for individual applications may vary, these agents generally are expected to aid the patient's coagulation system in the rapid development of an occlusive clot. Six commonly utilized hemostatic agents were quantitatively compared in terms of their ability to mediate platelet aggregation, deposition and activation, and initiate gross clot formation in a series of in vitro tests. Three types of collagen sponges (Actifoam, Helistat, Instat), microfibrillar collagen (Avitene), a gelatin sponge (Gelfoam), and oxidized regenerated cellulose (Surgicel) were studied. Platelet aggregation: Citrated platelet rich plasma (PRP) was contacted with hemostatic agents both with and without thrombin in a stirred cuvette and the platelet count was measured over 5 min. Platelet deposition: To approximate arterial wounds, PRP was perfused in a controlled manner through hemostatic agents, and the effluent platelet count was measured over time. Platelet activation: ATP secretion from PRP contacted with hemostatic agents in a stirred cuvette was measured at 1 and 5 min. Clot formation: The clotting time of nonanticoagulated whole blood contacted with the hemostatic agents was measured. Materials which depleted platelets most rapidly and effectively in the perfusion system (Avitene, Helistat, and Actifoam) were also the most effective inducers of platelet aggregation and secretion. Clot formation (likely to be platelet dependent) was also more rapid in this group. An overall activity ranking combined the relative performance of each hemostatic agent on the various tests: Actifoam ~ Avitene > Helistat >> Gelfoam > Instat > Surgicel. The activity ranking generally reflects the materials used in these agents (collagen > gelatin > oxidized regenerated cellulose), as well as their processing (chemical crosslinking in collagen sponges may lower activity). Such in vitro assessment of the relative platelet and coagulation activities of hemostatic agents might serve as a useful screening tool before investigating properties which require more expensive animal or clinical testing. AD - W.R. Wagner, Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, United States AU - Wagner, W. R. AU - Pachence, J. M. AU - Ristich, J. AU - Johnson, P. C. C1 - actifoam(Medchem International Pharmaceuticals,United States) avitene(Medchem International Pharmaceuticals,United States) gelfoam(Upjohn,United States) helistat(Life Science,United States) instat(Johnson and Johnson,United States) surgicel(Johnson and Johnson,United States) C2 - Johnson and Johnson(United States) Life Science(United States) Medchem International Pharmaceuticals(United States) Upjohn(United States) DB - Embase Medline DO - 10.1006/jsre.1996.0379 IS - 2 KW - actifoam adenosine triphosphate collagen gelatin gelfoam hemostatic sponge hemostatic agent instat microcrystalline collagen oxidized regenerated cellulose thrombin unclassified drug article blood clotting controlled study hemostasis human human tissue priority journal sponge thrombocyte activation thrombocyte aggregation platelet count thrombocyte function topical drug administration avitene helistat surgicel LA - English M3 - Article N1 - L27081878 1997-03-03 PY - 1996 SN - 0022-4804 SP - 100-108 ST - Comparative in vitro analysis of topical hemostatic agents T2 - Journal of Surgical Research TI - Comparative in vitro analysis of topical hemostatic agents UR - https://www.embase.com/search/results?subaction=viewrecord&id=L27081878&from=export http://dx.doi.org/10.1006/jsre.1996.0379 VL - 66 ID - 664 ER - TY - JOUR AB - Shaving with razors is often problematic in sensitive skin, especially skin of African Americans. This method of shaving often leads to erythema and irritation. Moreover, African American men are prone to pseudofolliculitis barbae (PFB), a common and distressing disorder in which growing hair shaft curve back into the skin, producing a foreign body inflammatory reaction. Depilatory creams chemically remove hair from the skin surface. The active ingredients of depilatory creams are chemicals that dissolve the keratin of hair. This controlled, single-center, split-faced, randomized trial was undertaken to compare shaving with two different depilatory products (product A, containing calcium hydroxide, guanidine carbonate, and calcium thioglycolate; and product B, containing calcium hydroxide, lithium hydroxide, and thioglycolic acid) to shaving with a razor on 45 African Americans male volunteers, 18 years of age or older, with skin prone to razors bumps. They were all current or previous users of depilatory cream. The volunteers underwent a sensitivity test and only qualified volunteers were enrolled into the study. The volunteers were required to shave at home with their normal method 2 days before the first visit. At the first visit, a dermatologist performed a preshave evaluation to assess irritation, skin roughness, and lesion count. Volunteers were asked to shave one half of the face with the provided razor and shaving cream and the other side with one of the depilatory creams (according to randomization). Immediately after shaving, a dermatologist performed the postshave evaluation by reassessing for irritation and efficacy, photographing both sides of the face, and counting lesions. The participant returned 2 and 4 days later and repeated the shaving technique. At each visit, a dermatologist repeated evaluation as described at the first visit. Volunteers completed a self-assessment questionnaire at each study visit. In this short study, the results indicate that there were fewer papules that developed on the depilatory-treated side compared to the razor shaved side in most subjects who used either of two products. While both depilatory products produced more irritation immediately after use and to a greater extent than the razor, the irritation was transient, and more often subjective than objective. The result of using either depilatory product was that the skin looked and felt smoother than shaving with a razor. Product A generated more irritant contact dermatitis than product B. All cases of irritant contact dermatitis resolved in 2 to 5 days without scarring or dyspigmentation. AD - C. Oresajo, L'Oréal Recherché, Clark, NJ, United States AU - Oresajo, C. AU - Kindred, C. AU - Yatskayer, M. AU - Halder, R. DB - Embase DO - 10.1016/j.jaad.2008.11.443 IS - 3 KW - thioglycolic acid calcium hydroxide guanidine carbonic acid calcium lithium keratin dermatology volunteer skin hair African American irritant dermatitis randomization self evaluation questionnaire papule inflammation skin surface scar formation foreign body male erythema LA - English M3 - Conference Abstract N1 - L70142116 2010-05-25 PY - 2009 SN - 0190-9622 SP - AB99 ST - Comparative evaluation of men's depilatory products versus razor T2 - Journal of the American Academy of Dermatology TI - Comparative evaluation of men's depilatory products versus razor UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70142116&from=export http://dx.doi.org/10.1016/j.jaad.2008.11.443 VL - 60 ID - 587 ER - TY - JOUR AB - BACKGROUND: The objective was to systematically review comparative economic analyses of patient safety improvements in the acute care setting. METHODS: A systematic review of 15 patient safety target conditions and six improvement strategies was conducted. The authors searched the published literature through Medline (2000-November 2011) using the following search terms for costs: 'costs and cost analysis', 'cost-effectiveness', 'cost' and 'financial management, hospital'. The methodological quality of potentially relevant studies was appraised using Cochrane rules of evidence for clinical effectiveness in quality improvement, and standard economic methods. RESULTS: The authors screened 2151 abstracts, reviewed 212 potentially eligible studies, and identified five comparative economic analyses that reported a total of seven comparisons based on at least one clinical effectiveness study of adequate methodological quality. Pharmacist-led medication reconciliation to prevent potential adverse drug events dominated (lower costs, better safety) a strategy of no reconciliation. Chlorhexidine for vascular catheter site care to prevent catheter-related bloodstream infections dominated a strategy of povidone-iodine for catheter site care. The Keystone ICU initiative to prevent central line-associated bloodstream infections was economically dominant over usual care. Detecting surgical foreign bodies using standard counting compared with a strategy of no counting had an incremental cost of US$1500 (CAN$1676) for each surgical foreign body detected. Several safety improvement strategies were less economically attractive, such as bar-coded sponges for reducing retained surgical sponges compared with standard surgical counting, and giving erythropoietin to reduce transfusion requirements in critically ill patients to avoid one transfusion-related adverse event. CONCLUSIONS: Five comparative economic analyses were found that reported a total of seven comparisons based on at least one effectiveness study of adequate methodological quality. On the basis of these limited studies, pharmacist-led medication reconciliation, the Keystone ICU intervention for central line-associated bloodstream infections, chlorhexidine for vascular catheter site care, and standard surgical sponge counts were economically attractive strategies for improving patient safety. More comparative economic analyses of such strategies are needed. AD - University of Toronto Centre for Patient Safety, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. edward.etchells@sunnybrook.ca AN - 22523319 AU - Etchells, E. AU - Koo, M. AU - Daneman, N. AU - McDonald, A. AU - Baker, M. AU - Matlow, A. AU - Krahn, M. AU - Mittmann, N. DA - Jun DO - 10.1136/bmjqs-2011-000585 DP - NLM ET - 2012/04/24 IS - 6 KW - Costs and Cost Analysis/methods Cross Infection/prevention & control Emergency Service, Hospital/*economics Humans Medication Errors/prevention & control Patient Safety/*economics LA - eng N1 - 2044-5423 Etchells, Edward Koo, Marika Daneman, Nick McDonald, Andrew Baker, Michael Matlow, Anne Krahn, Murray Mittmann, Nicole Journal Article Research Support, Non-U.S. Gov't Review Systematic Review England BMJ Qual Saf. 2012 Jun;21(6):448-56. doi: 10.1136/bmjqs-2011-000585. Epub 2012 Apr 22. PY - 2012 SN - 2044-5415 SP - 448-56 ST - Comparative economic analyses of patient safety improvement strategies in acute care: a systematic review T2 - BMJ Qual Saf TI - Comparative economic analyses of patient safety improvement strategies in acute care: a systematic review VL - 21 ID - 125 ER - TY - JOUR AB - OBJECTIVES: Implant-associated methicillin-resistant Staphylococcus aureus (MRSA) infections are challenging to treat. We compared antimicrobial activities in a rat model of chronic osteomyelitis in the context of retention of the foreign body without débridement. METHODS: MRSA was inoculated into the proximal tibia and a wire implanted. Four weeks after infection, treatment with vancomycin 50 mg/kg every 12 h, tigecycline 14 mg/kg every 12 h, rifampin 25 mg/kg every 12 h, or the combination of vancomycin or tigecycline plus rifampin was administered intraperitoneally for 21 days. RESULTS: MRSA was cultured from all tibias in the control group (median, 6.06 log10 CFU/g bone). Median bacterial counts (log10 CFU/g) at 48 h post-treatment were 6.16 for vancomycin (p = 0.753), 2.29 for vancomycin plus rifampin (p < 0.001), 5.90 for tigecycline (p = 0.270), 0.10 for tigecycline plus rifampin (p < 0.001), and 0.91 for rifampin (p = 0.044) treatment. Three deaths were observed in the tigecycline plus rifampin group. Median bacterial counts (log10 CFU/g) at two weeks post-treatment were 5.65 for vancomycin (p = 0.6), 4.05 for vancomycin plus rifampin (p = 0.105), 5.68 for tigecycline (p = 0.401), 4.05 for tigecycline plus rifampin (p = 0.028), and 5.98 for rifampin (p = 0.297) treatment. CONCLUSIONS: Tigecycline plus rifampin resulted in a significant bacterial count decrease, an effect more prominent at 48 h than two weeks after treatment completion. Tigecycline was not well tolerated at the dose studied. AD - Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, United States. Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, United States. Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, MN 55905, United States. Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, United States; Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, MN 55905, United States. Electronic address: patel.robin@mayo.edu. AN - 25576292 AU - Vergidis, P. AU - Schmidt-Malan, S. M. AU - Mandrekar, J. N. AU - Steckelberg, J. M. AU - Patel, R. DA - Jun DO - 10.1016/j.jinf.2014.12.016 DP - NLM ET - 2015/01/13 IS - 6 KW - Animals Anti-Bacterial Agents/*pharmacology Disease Models, Animal Humans Male Methicillin/pharmacology Methicillin Resistance Methicillin-Resistant Staphylococcus aureus/*drug effects Minocycline/analogs & derivatives/pharmacology Osteomyelitis/*drug therapy/microbiology Rats Rats, Wistar Rifampin/pharmacology Staphylococcal Infections/*drug therapy/microbiology Tigecycline Vancomycin/pharmacology Osteomyelitis Rifampin Staphylococcus aureus Vancomycin LA - eng N1 - 1532-2742 Vergidis, Paschalis Schmidt-Malan, Suzannah M Mandrekar, Jayawant N Steckelberg, James M Patel, Robin Comparative Study Journal Article Research Support, Non-U.S. Gov't England J Infect. 2015 Jun;70(6):609-15. doi: 10.1016/j.jinf.2014.12.016. Epub 2015 Jan 7. PY - 2015 SN - 0163-4453 SP - 609-15 ST - Comparative activities of vancomycin, tigecycline and rifampin in a rat model of methicillin-resistant Staphylococcus aureus osteomyelitis T2 - J Infect TI - Comparative activities of vancomycin, tigecycline and rifampin in a rat model of methicillin-resistant Staphylococcus aureus osteomyelitis VL - 70 ID - 156 ER - TY - JOUR AB - Basidiobolomycosis is a rare fungal disease caused by Basidiobolus ranarum, which is endemic in tropical and subtropical regions of Africa, Asia, and Latin America. Gastrointestinal basidiobolomycosis poses diagnostic difficulties due to the non-specific clinical presentation and absence of predisposing factors. Eight pediatric cases of the disease have been reported recently from Iran, but none of these, or most of the other cases reported in the literature, has been proven by culture, which is the gold standard method for diagnosis. We present a case of culture-proven colonic basidiobolomycosis that occurred in a 3-year-old boy. The outcome was successful following surgical excision and antifungal therapy with posaconazole. © 2014 The Authors. AD - Department of Pathology, Dr Sheikh Children Hospital, Mashhad University of Medical Sciences, Mashhad, Iran Department of Parasitology and Mycology, Imam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Department of Radiology, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran Pediatric Surgery Department, Dr Sheikh Children Hospital, Mashhad University of Medical Sciences, Mashhad, Iran Department of Pediatrics and the Infection Control and Hand Hygiene Research Center, Imam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran AU - Zabolinejad, N. AU - Naseri, A. AU - Davoudi, Y. AU - Joudi, M. AU - Aelami, M. H. DB - Scopus DO - 10.1016/j.ijid.2013.11.016 KW - Basidiobolomycosis Child Gastrointestinal Posaconazole M3 - Article N1 - Cited By :10 Export Date: 10 November 2020 PY - 2014 SP - 41-43 ST - Colonic basidiobolomycosis in a child: Report of a culture-proven case T2 - International Journal of Infectious Diseases TI - Colonic basidiobolomycosis in a child: Report of a culture-proven case UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84897031497&doi=10.1016%2fj.ijid.2013.11.016&partnerID=40&md5=68d5c0dde2dc4f580bf61ff4ead2ebb8 VL - 22 ID - 1291 ER - TY - JOUR AB - Background: Colon stenosis and acute appendicitis are rare diseases among premature babies. To the best of our knowledge, no study has identified both the conditions in preterm babies. Case presentation: Here we report a case of a preterm Japanese male baby who developed ascending colon stenosis and appendicitis. During his neonatal intensive care unit stay, he developed increasing apnea and vomiting with rapidly worsening abdominal distention. Contrast radiographs indicated colon stenosis. Emergent exploratory laparotomy revealed ascending colon stenosis with appendix adhesion; both the lesions were surgically resected. The pathological findings suggested that he had appendicitis several weeks prior to the surgery; the onset of colon lesion seemed later than that of appendix. The perforated appendix was covered by the ascending colon, and inflammatory reactions led to the narrowing of the intestinal lumen. Conclusions: Neonatal appendicitis and colon stenosis are both challenging for the diagnosis, and early laparotomy is necessary when these conditions are suspected. © 2019 The Author(s). AD - Department of Neonatology, Osaka Red Cross Hospital, 5-30, Fudegasakicho, Tennoji Ward, Osaka, Japan Department of Pediatrics, Osaka Red Cross Hospital, 5-30, Fudegasakicho, Tennoji Ward, Osaka, Japan Department of Pediatric Surgery, Osaka Red Cross Hospital, 5-30, Fudegasakicho, Tennoji Ward, Osaka, Japan Department of Pathology, Osaka Red Cross Hospital, 5-30, Fudegasakicho, Tennoji Ward, Osaka, Japan AU - Naito, T. AU - Teramen, H. AU - Hayashi, H. AU - Takegawa, M. AU - Sakamoto, H. AU - Shimada, T. AU - Ohno, K. AU - Yoshii, M. C7 - s12887-019-1873-0 DB - Scopus DO - 10.1186/s12887-019-1873-0 IS - 1 KW - Colon stenosis Neonatal appendicitis Preterm M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2019 ST - Colon stenosis due to acute neonatal appendicitis in a preterm baby: a case report T2 - BMC Pediatrics TI - Colon stenosis due to acute neonatal appendicitis in a preterm baby: a case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076459298&doi=10.1186%2fs12887-019-1873-0&partnerID=40&md5=e5402e8efc2cc7f7b4101ca30d854ee7 VL - 19 ID - 989 ER - TY - JOUR AB - This prospective study was conducted to compare inflammatory responses between patients receiving coated and uncoated vascular prostheses, and to examine their effect on length of stay and cost of patients undergoing abdominal aortic aneurysmectomy. Patients undergoing elective vascular reconstruction of an abdominal aortic aneurysm were assigned randomly to coated-graft or uncoated-graft groups (n = 20, for each group). Interleukin (IL)-6, granulocyte elastase, white blood cell count, C-reactive protein (CRP), and body temperature (BT) were prospectively recorded preoperatively and on postoperative days (PODs) 1, 3, 7, and 14. In-hospital stay and hospitalized costs were also analyzed. IL-6 and CRP concentrations in the coated-graft group were higher than those in the uncoated-graft group (P = 0.01 and 0.05). BT was more frequently elevated >37°C at POD 14 in the coated-graft group than in the uncoated-graft group (P =0.03). Discharge was delayed, and overall hospitalization cost was higher in the coated-graft group than in the uncoated group (17.6 vs. 13.5 days, and 2 010 000 vs. 1 780 000 yen, P = 0.006 and P = 0.002, respectively). Coated vascular prosthesis demonstrated more profound inflammatory reaction than noncoated prosthesis, postoperatively. © 2007, Copyright the Authors. AD - Second Department of Surgery, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo-city, Yamanashi 409-3898, Japan Second Department of Surgery, University of Yamanashi, Chuo-city, Yamanashi, Japan AU - Shindo, S. AU - Motohashi, S. AU - Katsu, M. AU - Kaga, S. AU - Inoue, H. AU - Matsumoto, M. DB - Scopus DO - 10.1111/j.1525-1594.2007.00521.x IS - 3 KW - Aortic surgery Coated graft Gelatin Hospitalization cost Inflammation Vascular prosthesis M3 - Article N1 - Cited By :8 Export Date: 10 November 2020 PY - 2008 SP - 183-187 ST - Coated prostheses are associated with prolonged inflammation in aortic surgery: A cost analysis T2 - Artificial Organs TI - Coated prostheses are associated with prolonged inflammation in aortic surgery: A cost analysis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-40149088177&doi=10.1111%2fj.1525-1594.2007.00521.x&partnerID=40&md5=f1616b7d194cb770995813fd3132a3c1 VL - 32 ID - 1534 ER - TY - JOUR AB - Textiloma is a term used for retained cottonoid or surgical sponge in the operation field. Although they occur mostly after thoracic or abdominal operation, they can also be encountered after surgery of extremities or the spine. There are few reports of spinal cases in which MR and CT imaging findings of textilomas have been described. In this report, two additional cases with MR, CT and pathological features of paraspinal textilomas are described. CT image demonstrated a paraspinal mass simulating a malignant tumour. While T1-weighted MR images showed the masses with low signal intensity, T2-weighted MR images showed heterogeneous masses with low and high signal intensities. AD - Haydarpaşa Numune Teaching and Research Hospital, Department of Neurosurgery, Üsküdar, Istanbul, Turkey Trakya University, School of Medicine, Edirne, Turkey Department of Pathology, Haydarpaşa Numune Teaching and Research Hospital, Istanbul, Turkey AU - Hakan, T. AU - Aydoseli, A. AU - Demir, K. AU - Aker, F. DB - Scopus IS - 5 KW - Foreign body Gauzoma Gossypiboma Textiloma M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2009 SP - 475-478 ST - Clinical, pathological and radiological features of paraspinal textiloma: Report of two cases and review of the literature T2 - Neurologia i Neurochirurgia Polska TI - Clinical, pathological and radiological features of paraspinal textiloma: Report of two cases and review of the literature UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-70449635527&partnerID=40&md5=e2f22ee2a71a4785be9c01c6a71410f4 VL - 43 ID - 1483 ER - TY - JOUR AB - Perineal injury sustained during childbirth, and more particularly third and fourth degree tears, can have substantial effects on future continence, sexual function and the choice of method of childbirthin the future. The aim of our audit was to see if the use of clinical risk management methods couldhelp improve documentation and clincial outcomes for women who sustained an obstetric anal sphincter injury. A proforma for the management of obstetric anal sphincter injury was introduced to the labour ward. We found that after the introduction of the proforma documentation improvedsignificantly for classification of the type of injury (P , .01), counts of swabs, instruments and sharps(P , .01) and future pregnancy information (P , .05). This audit demonstrates how simple clinical risk management strategies can help ensure the best standards of care are implemented. AD - Rotunda Hospital, Parnell Square, Dublin 1 AN - 104457314. Language: English. Entry Date: 20120706. Revision Date: 20200708. Publication Type: Journal Article AU - Burke, N. AU - Corcoran, S. AU - Ryan, H. AU - Barrett, N. AU - Geary, M. DB - ccm DO - 10.1258/cr.2011.011042 DP - EBSCOhost IS - 1 KW - Obstetrics Risk Management Anus -- Injuries -- In Pregnancy Tears and Lacerations -- Prevention and Control Pregnancy Female Audit Documentation Human Descriptive Statistics Chi Square Test Fisher's Exact Test Surgery, Operative -- Methods Surgical Count Procedure Antibiotics -- Therapeutic Use Physical Therapy Incidence Practice Guidelines Analgesics -- Therapeutic Use N1 - research; tables/charts. Journal Subset: Editorial Board Reviewed; Europe; Expert Peer Reviewed; Health Services Administration; Peer Reviewed; UK & Ireland. Special Interest: Obstetric Care; Women's Health. NLM UID: 9512518. PY - 2012 SN - 1356-2622 SP - 19-22 ST - Clinical risk management of obstetric anal sphincter injury T2 - Clinical Risk TI - Clinical risk management of obstetric anal sphincter injury UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104457314&site=ehost-live&scope=site VL - 18 ID - 753 ER - TY - JOUR AB - Purpose: To describe the clinical presentations and treatment modalities of a series of BB gun-related perforating ocular injuries. Methods: Clinical records of all consecutive cases of perforating BB gun injuries to the globe seen between September 2004 and September 2008 were reviewed retrospectively. At the time of the trauma and after final treatment, all patients underwent a complete ocular examination, including visual acuity, applanation tonometry for intraocular pressure, slit lamp biomicroscopy, indirect ophthalmoscopy and fundus photography, if possible. In all cases, primary globe repair was performed in the first session, and then appropriate surgery took place based on the individual situation. Results: In this study, 13 patients (11 males and 2 females) with a mean age of 20.8 years (range 9-50 years) were enrolled. The mean follow-up period was 7.2 ± 4.3 months (range 1-25 months). Initial visual acuity (VA) ranged from no-light perception (NLP) to finger counting (CF). Vitreous haemorrhage and retinal detachment were present in all involved eyes. Hyphema (30.76%), uveal and retinal prolapse (30.8%), retinal incarceration (30.8%) and retinal haemorrhage (53.8%) were other ocular findings. VA remained stable in 46.2% of the patients (6 cases). The best achieved final VA was CF at 2 m in one case after 6 months follow-up. After several surgical procedures, enucleation was necessary in only 2/13 (15.4%) cases. Conclusion: Despite several surgical procedures which decreased the number of enucleations, BB gun-perforating ocular injuries still lead to a grim visual outcome. This implies the importance of political strategies targeting on education of parents and restriction for children to access to these guns. © 2010 Elsevier Ltd. All rights reserved. AD - A. Kord Valeshabad, P.O. Box 13185-1678, Tehran, Iran AU - Nili Ahmadabadi, M. AU - Karkhaneh, R. AU - Kord Valeshabad, A. AU - Tabatabai, A. AU - Jager, M. J. AU - Nili Ahmadabadi, E. DB - Embase Medline DO - 10.1016/j.injury.2010.11.006 IS - 5 KW - adolescent adult article ball bearing gun child clinical article computer assisted tomography eye examination eye fundus eye injury eye photography female firearm follow up foreign body human hyphema intraocular pressure male oculoplethysmography ophthalmoscopy penetrating trauma priority journal retina detachment retrospective study school child slit lamp tissue injury vision visual acuity vitreous hemorrhage LA - English M3 - Article N1 - L51181871 2010-12-10 2011-04-14 PY - 2011 SN - 0020-1383 SP - 492-495 ST - Clinical presentation and outcome of perforating ocular injuries due to BB guns: A case series T2 - Injury TI - Clinical presentation and outcome of perforating ocular injuries due to BB guns: A case series UR - https://www.embase.com/search/results?subaction=viewrecord&id=L51181871&from=export http://dx.doi.org/10.1016/j.injury.2010.11.006 VL - 42 ID - 541 ER - TY - JOUR AB - The objective of this study was to investigate the therapeutic effects of bronchoscopy alveolar lavage (BAL) combined with thoracoscopy in the treatment of empyema in children.Retrospectively analyzed 174 cases of pediatric empyema treated with thoracoscopy combined with BAL from January 2010 to December 2016 in our hospital. All the cases, according to admission order, were randomly divided into 2 groups, the control group (group A), which contained 89 cases, was treated with thoracoscopy; and the experimental group (group B), which contained 85 cases, was treated with BAL combined with thoracoscopy. The results of BAL treatment, the inflammatory indexes including body temperature, total leukocyte count in peripheral blood and CRP, and the therapeutic effect and prognosis including the days of antibiotic use, hospital stay, the incidence of thoracotomy and lobectomy were compared between the 2 groups.1.There was no significant difference in inflammatory indexes between the 2 groups: body temperature (oC), (39.06±0.047 and 39.08±0.050), P>.855; routine leukocyte count (10^9/L), (25.93±1.035 and 24.76±1.019), P>.425); C-reactive protein (mg/L), (128.7±6.653 and 138.6±7.53), P>.328.2.The results of BAL: hyperemia and edema was detected in trachea intima of all cases, including 32 cases of purulent secretion and ulcer, 21 cases of lumen deformation and 5 cases of foreign body.3.There were statistical significances in the curative effects of the control group and the experimental group: the duration of antibiotic use (days), (21.07±0.342 and 17.07±0.288), P<.0001); the average hospital stay (days), (22.91±0.347 and 18.79±0.287), P<.0001; secondary surgery (thoracotomy), 15 cases in the control group, 5 cases in the experimental group, P<.023; lung lobectomy (disability rate), 13 cases in the control group and 3 cases in the experimental group, P<.011.There was statistical difference in all the therapeutic indexes (P<.05).Bronchoscopy alveolar lavage combined with thoracoscopy has a higher success rate in the treatment of pediatric empyema, and is more comprehensive, safe and effective in controlling inflammation. AD - F. Yue, Pediatric Thoracic Surgery, Children Hospitial of Hebei Province, No.133, Jianhua Road, Yuhua District, Shijiazhuang, China AU - Yue, F. AU - Yang, Z. AU - Yang, F. AU - Liu, Y. AU - Zhao, L. AU - Chen, Z. AU - Gao, F. DB - Embase Medline DO - 10.1097/MD.0000000000018528 IS - 52 KW - article bronchoalveolar lavage fluid bronchoscopy child clinical observation controlled study edema female foreign body human hyperemia intima length of stay lung lobectomy major clinical study male pleura empyema preschool child priority journal retrospective study suppuration therapeutic index thoracoscopy thoracotomy trachea ulcer LA - English M3 - Article N1 - L630548976 2020-01-14 2020-01-21 PY - 2019 SN - 1536-5964 0025-7974 ST - Clinical observation of bronchoscopy alveolar lavage combined with thoracoscopy in the treatment of empyema in children T2 - Medicine (United States) TI - Clinical observation of bronchoscopy alveolar lavage combined with thoracoscopy in the treatment of empyema in children UR - https://www.embase.com/search/results?subaction=viewrecord&id=L630548976&from=export http://dx.doi.org/10.1097/MD.0000000000018528 VL - 98 ID - 302 ER - TY - JOUR AN - 106659046. Language: English. Entry Date: 20050712. Revision Date: 20150818. Publication Type: Journal Article AU - Petersen, C. DB - ccm DO - 10.1016/S0001-2092(06)60571-1 DP - EBSCOhost IS - 2 KW - Operating Rooms -- Administration Perioperative Nursing AORN -- Standards Asepsis Gloves -- Utilization Insects Plants Protective Clothing -- Utilization Retained Instruments Sterilization and Disinfection Surgery Schedule Surgical Count Procedure Time Factors N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2004 SN - 0001-2092 SP - 321-324 ST - Clinical issues. Time for unused sterile setups; maintaining instrument count sheets; gowning off back tables; plants in the OR; count discrepancies T2 - AORN Journal TI - Clinical issues. Time for unused sterile setups; maintaining instrument count sheets; gowning off back tables; plants in the OR; count discrepancies UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106659046&site=ehost-live&scope=site VL - 80 ID - 800 ER - TY - JOUR AN - 106870356. Language: English. Entry Date: 20030926. Revision Date: 20150818. Publication Type: Journal Article AU - Petersen, C. DB - ccm DO - 10.1016/S0001-2092(06)61352-5 DP - EBSCOhost IS - 1 KW - Operating Rooms -- Administration Perioperative Nursing Air Conditioning Fever -- Prevention and Control Operating Rooms Surgical Count Procedure Surgical Draping Surgical Sponges Warming Techniques Wounds and Injuries Wounds and Injuries -- Classification N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2003 SN - 0001-2092 SP - 123-131 ST - Clinical issues. Table overhang; hypothermia; separating sponges; skin lacerations when scrubbing; wound classification; forced air warming T2 - AORN Journal TI - Clinical issues. Table overhang; hypothermia; separating sponges; skin lacerations when scrubbing; wound classification; forced air warming UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106870356&site=ehost-live&scope=site VL - 78 ID - 865 ER - TY - JOUR AN - 106994673. Language: English. Entry Date: 20010202. Revision Date: 20150818. Publication Type: Journal Article AU - Petersen, C. DB - ccm DO - 10.1016/S0001-2092(06)61913-3 DP - EBSCOhost IS - 6 KW - Perioperative Nursing Operating Rooms -- Administration Bone Transplantation Sterilization and Disinfection Joint Commission Surgicenters -- Administration RN First Assistants Credentialing Surgical Sponges Surgical Count Procedure N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PMID: NLM11141707. PY - 2000 SN - 0001-2092 SP - 1064-1066 ST - Clinical issues. Sterilizing bone grafts; accreditation; private scrub people and first assistants; including towels in counts T2 - AORN Journal TI - Clinical issues. Sterilizing bone grafts; accreditation; private scrub people and first assistants; including towels in counts UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106994673&site=ehost-live&scope=site VL - 72 ID - 920 ER - TY - JOUR AN - 106720263. Language: English. Entry Date: 20040409. Revision Date: 20150818. Publication Type: Journal Article AU - Conner, R. DB - ccm DO - 10.1016/S0001-2092(06)61157-5 DP - EBSCOhost IS - 1 KW - Operating Rooms -- Administration Perioperative Nursing Medical Orders Joint Commission -- Standards Hospital Policies Sterilization and Disinfection Automation Endoscopes Reagent Strips Operating Room Information Systems Nursing Records Time Factors Central Service Department -- Administration Surgical Count Procedure N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2004 SN - 0001-2092 SP - 230-234 ST - Clinical issues. Standing orders; automated endoscopic reprocessors; documentation; central service department attire; counting ligaclips T2 - AORN Journal TI - Clinical issues. Standing orders; automated endoscopic reprocessors; documentation; central service department attire; counting ligaclips UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106720263&site=ehost-live&scope=site VL - 79 ID - 864 ER - TY - JOUR AD - Perioperative Nursing Specialist, AORN Center for Nursing Practice AN - 106640089. Language: English. Entry Date: 20050603. Revision Date: 20150818. Publication Type: Journal Article AU - Petersen, C. AU - Burlingame, B. L. DB - ccm DO - 10.1016/S0001-2092(06)60364-5 DP - EBSCOhost IS - 4 KW - Operating Rooms -- Administration Perioperative Nursing Asepsis Clothing Disposable Equipment -- Utilization Equipment Safety Physicians Prostheses and Implants Sterilization and Disinfection Eye Surgery Surgical Count Procedure Surgical Equipment and Supplies Surgical Instruments Uniforms United States Occupational Safety and Health Administration N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2005 SN - 0001-2092 SP - 851-855 ST - Clinical issues. Safety scalpels; turnover time; personal clothing; implant sterilization; using suture packets to rectify counts T2 - AORN Journal TI - Clinical issues. Safety scalpels; turnover time; personal clothing; implant sterilization; using suture packets to rectify counts UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106640089&site=ehost-live&scope=site VL - 81 ID - 803 ER - TY - JOUR AN - 106976456. Language: English. Entry Date: 20021108. Revision Date: 20150818. Publication Type: Journal Article AU - Petersen, C. DB - ccm DO - 10.1016/S0001-2092(06)61667-0 DP - EBSCOhost IS - 3 KW - Operating Rooms -- Administration Perioperative Nursing Surgical Count Procedure Needles Surgery, Operative Electric Stimulation Electrosurgery -- Adverse Effects Gloves -- Utilization Equipment Reuse Sterilization and Disinfection -- Standards N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2002 SN - 0001-2092 SP - 510-515 ST - Clinical issues. Rectifying counts; neurostimulators; double gloving; reprocessing single-use devices; simultaneous counting T2 - AORN Journal TI - Clinical issues. Rectifying counts; neurostimulators; double gloving; reprocessing single-use devices; simultaneous counting UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106976456&site=ehost-live&scope=site VL - 76 ID - 873 ER - TY - JOUR AD - Perioperative Nursing Specialist, AORN Center for Nursing Practice AN - 105939057. Language: English. Entry Date: 20080125. Revision Date: 20150818. Publication Type: Journal Article AU - Denholm, B. DB - ccm DP - EBSCOhost IS - 5 KW - Surgical Count Procedure -- In Infancy and Childhood Hospital Policies Infant Inpatients Outpatients N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2007 SN - 0001-2092 SP - 853-855 ST - Clinical issues. Pediatric instrument counts T2 - AORN Journal TI - Clinical issues. Pediatric instrument counts UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105939057&site=ehost-live&scope=site VL - 86 ID - 853 ER - TY - JOUR AN - 106746036. Language: English. Entry Date: 20040618. Revision Date: 20150818. Publication Type: Journal Article AU - Fogg, D. DB - ccm DO - 10.1016/S0001-2092(06)60917-4 DP - EBSCOhost IS - 3 KW - Operating Rooms -- Administration Perioperative Nursing Beds and Mattresses Sterilization and Disinfection Surgicenters -- Administration Infection Control Handwashing Antiinfective Agents Latex Hypersensitivity -- Prevention and Control Environmental Exposure -- Prevention and Control Patient Safety Skin Preparation, Surgical Surgical Count Procedure Documentation Wound Care N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2004 SN - 0001-2092 SP - 645-652 ST - Clinical issues. Mattress disinfection; hand hygiene; latex safety; abdominal-perineal preps; hand rub characteristics; radiopaque packing T2 - AORN Journal TI - Clinical issues. Mattress disinfection; hand hygiene; latex safety; abdominal-perineal preps; hand rub characteristics; radiopaque packing UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106746036&site=ehost-live&scope=site VL - 79 ID - 863 ER - TY - JOUR AN - 106272688. Language: English. Entry Date: 20070427. Revision Date: 20150818. Publication Type: Journal Article AU - Denholm, B. DB - ccm DO - 10.1016/S0001-2092(07)60051-9 DP - EBSCOhost IS - 2 KW - Malignant Hyperthermia Perioperative Nursing Sterilization and Disinfection -- Evaluation Surgical Count Procedure Hospitals Malignant Hyperthermia -- Drug Therapy Malignant Hyperthermia -- Risk Factors Malignant Hyperthermia -- Symptoms Surgicenters Sutures N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2007 SN - 0001-2092 SP - 403-413 ST - Clinical issues. Malignant hyperthermia; sterilization monitoring; sterilization indicators; multipack needle counts T2 - AORN Journal TI - Clinical issues. Malignant hyperthermia; sterilization monitoring; sterilization indicators; multipack needle counts UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106272688&site=ehost-live&scope=site VL - 85 ID - 798 ER - TY - JOUR AN - 106799378. Language: English. Entry Date: 20030124. Revision Date: 20150818. Publication Type: Journal Article AU - Fogg, D. DB - ccm DO - 10.1016/S0001-2092(06)61046-6 DP - EBSCOhost IS - 5 KW - Operating Rooms -- Administration Perioperative Nursing Antiinfective Agents Handwashing Fires Surgical Count Procedure Surgical Draping Music Skin Preparation, Surgical N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2002 SN - 0001-2092 SP - 889-892 ST - Clinical issues. Flammable hand scrubs; people who should count; draping; OR music; inserting central venous catheters T2 - AORN Journal TI - Clinical issues. Flammable hand scrubs; people who should count; draping; OR music; inserting central venous catheters UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106799378&site=ehost-live&scope=site VL - 76 ID - 872 ER - TY - JOUR AN - 106944049. Language: English. Entry Date: 20020802. Revision Date: 20150818. Publication Type: Journal Article AU - Petersen, C. DB - ccm DO - 10.1016/S0001-2092(06)61620-7 DP - EBSCOhost IS - 6 KW - Operating Rooms -- Administration Perioperative Nursing Air Conditioning Fire Safety Nails Plants Surgical Count Procedure Surgical Fires -- Prevention and Control Surgicenters -- Administration N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2002 SN - 0001-2092 SP - 1175-1178 ST - Clinical issues. Fire safety; instrument counts; plants in OR areas; portable humidity and air-conditioning units; artificial nails T2 - AORN Journal TI - Clinical issues. Fire safety; instrument counts; plants in OR areas; portable humidity and air-conditioning units; artificial nails UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106944049&site=ehost-live&scope=site VL - 75 ID - 874 ER - TY - JOUR AN - 106894743. Language: English. Entry Date: 20020125. Revision Date: 20150818. Publication Type: Journal Article AU - Fogg, D. M. DB - ccm DO - 10.1016/S0001-2092(06)61774-2 DP - EBSCOhost IS - 5 KW - Operating Rooms -- Administration Perioperative Nursing Creutzfeldt-Jakob Syndrome -- Prevention and Control Sterilization and Disinfection Disposable Equipment Product Labeling Hair Removal Skin Preparation, Surgical Surgical Count Procedure N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2001 SN - 0001-2092 SP - 726-729 ST - Clinical issues. Creutzfeldt-Jakob disease; single use devices; third party reprocessors; hair removal; instrument counts...Creutzfeldt T2 - AORN Journal TI - Clinical issues. Creutzfeldt-Jakob disease; single use devices; third party reprocessors; hair removal; instrument counts...Creutzfeldt UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106894743&site=ehost-live&scope=site VL - 74 ID - 875 ER - TY - JOUR AN - 105729058. Language: English. Entry Date: 20080530. Revision Date: 20150818. Publication Type: Journal Article AU - Downing, D. DB - ccm DP - EBSCOhost IS - 4 KW - Radio Frequency Identification Surgical Count Procedure -- Methods Surgical Equipment and Supplies Patient Safety Practice Guidelines N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2008 SN - 0001-2092 SP - 823-826 ST - Clinical issues. Counting sterile towels T2 - AORN Journal TI - Clinical issues. Counting sterile towels UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105729058&site=ehost-live&scope=site VL - 87 ID - 817 ER - TY - JOUR AN - 106431257. Language: English. Entry Date: 20121130. Revision Date: 20150818. Publication Type: Journal Article AU - Denholm, B. DB - ccm DO - 10.1016/S0001-2092(06)60244-5 DP - EBSCOhost IS - 1 KW - Operating Rooms -- Administration Perioperative Nursing Influenza Vaccine Influenza -- Complications Occupational Health Organ Procurement Sterilization and Disinfection Surgical Count Procedure N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2006 SN - 0001-2092 SP - 231-239 ST - Clinical issues. Counting miscellaneous items; counting during organ procurement; counting for sequential procedures; influenza vaccine; reprocessing T2 - AORN Journal TI - Clinical issues. Counting miscellaneous items; counting during organ procurement; counting for sequential procedures; influenza vaccine; reprocessing UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106431257&site=ehost-live&scope=site VL - 83 ID - 802 ER - TY - JOUR AN - 107066861. Language: English. Entry Date: 20011109. Revision Date: 20150818. Publication Type: Journal Article AU - Petersen, C. DB - ccm DO - 10.1016/S0001-2092(06)61796-1 DP - EBSCOhost IS - 3 KW - Perioperative Nursing Operating Rooms -- Administration Surgical Count Procedure Foreign Bodies Operating Room Personnel Infection Control Methicillin Resistance Staphylococcal Infections Patient Isolation N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2001 SN - 0001-2092 SP - 393-396 ST - Clinical issues. Count processes; counting towels; intraoperative sneezes; sponge disposal; contact precautions T2 - AORN Journal TI - Clinical issues. Count processes; counting towels; intraoperative sneezes; sponge disposal; contact precautions UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107066861&site=ehost-live&scope=site VL - 74 ID - 860 ER - TY - JOUR AN - 106926539. Language: English. Entry Date: 20020531. Revision Date: 20150818. Publication Type: Journal Article AU - Conner, R. DB - ccm DO - 10.1016/S0001-2092(06)61647-5 DP - EBSCOhost IS - 4 KW - Operating Rooms -- Administration Perioperative Nursing Asepsis Materials Management Skin Preparation, Surgical Sterilization and Disinfection Surgical Count Procedure N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2002 SN - 0001-2092 SP - 861-863 ST - Clinical issues. Brooms/dust mops; damp dusting; counting endo bags; scrub person sitting; sterile storage; navel prep T2 - AORN Journal TI - Clinical issues. Brooms/dust mops; damp dusting; counting endo bags; scrub person sitting; sterile storage; navel prep UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106926539&site=ehost-live&scope=site VL - 75 ID - 890 ER - TY - JOUR AB - THIS MONTH: Surgical counts during a partial cystectomy Key words: partial cystectomy, retained surgical item (RSI), counts, bladder, guidewire. Preparing the OR for patients who require both airborne and contact precautions Key words: airborne precautions, contact precautions, contamination, Coronavirus Disease 2019 (COVID‐19), negative pressure. Preoperative transport of patients who require both airborne and contact precautions Key words: preoperative patient transport, hand hygiene, personal protective equipment (PPE), N95 respirator, Coronavirus Disease 2019 (COVID‐19). Postoperative transport of patients who require both airborne and contact precautions Key words: postoperative patient transport, hand hygiene, personal protective equipment (PPE), N95 respirator, Coronavirus Disease 2019 (COVID‐19). AN - 145364109. Language: English. Entry Date: 20200903. Revision Date: 20200903. Publication Type: Article AU - Jones, Emily AU - Wood, Amber DB - ccm DO - 10.1002/aorn.13165 DP - EBSCOhost IS - 3 KW - Perioperative Nursing Patient Safety Cystectomy Education, Continuing (Credit) Surgical Count Procedure Operating Rooms Transportation of Patients Preoperative Care Postoperative Care Infection Control AORN N1 - CEU; exam questions; pictorial; questions and answers. Note: For CE see http://www.aornj​ournal. org/conte​nt/cme.. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2020 SN - 0001-2092 SP - 291-300 ST - Clinical Issues—September 2020 T2 - AORN Journal TI - Clinical Issues—September 2020 UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=145364109&site=ehost-live&scope=site VL - 112 ID - 703 ER - TY - JOUR AB - THIS MONTH: Using adhesive tape for patient positioning Key words: adhesive tape, surgical tape, patient positioning, pressure injury, contamination. Border sterility of open sterile wrappers Key words: wrapped sterile item, unsterile border, wrapper flap, contaminated, aseptic technique. Cost per minute of OR time Key words: cost comparison, direct costs, cost savings, perioperative efficiency, product evaluation. Packages containing an incorrect number of suture needles Key words: multipack, retained surgical item (RSI), counting, needle, package. AN - 146677446. Language: English. Entry Date: 20201107. Revision Date: 20201107. Publication Type: Article AU - Seeman, Kristyn DB - ccm DO - 10.1002/aorn.13238 DP - EBSCOhost IS - 5 KW - Practice Guidelines Patient Positioning Surgical Equipment and Supplies Health Care Costs Sterilization and Disinfection Surgical Count Procedure Product Packaging Preceptorship Education, Continuing (Credit) Patient Safety Nursing Practice, Evidence-Based Perioperative Nursing Surgery, Operative Equipment Contamination Shared Governance, Nursing Operating Rooms Information Resources N1 - exam questions; pictorial; questions and answers. Note: For CE go to http://www.aornjournal.org/content/cme. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2020 SN - 0001-2092 SP - 568-574 ST - Clinical Issues—November 2020 T2 - AORN Journal TI - Clinical Issues—November 2020 UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=146677446&site=ehost-live&scope=site VL - 112 ID - 704 ER - TY - JOUR AN - 130399823. Language: English. Entry Date: 20180702. Revision Date: 20200324. Publication Type: Article AU - Cahn, Julie AU - Burlingame, Byron L. DB - ccm DO - 10.1002/aorn.12296 DP - EBSCOhost IS - 1 KW - Perioperative Care Operating Rooms Education, Continuing (Credit) Formaldehyde Occupational Safety -- Standards Occupational Exposure -- Prevention and Control Materials Management Protective Devices Surgical Sponges Surgical Count Procedure Retained Instruments Infection Control GI Laboratories Security Measures Health Facility Environment N1 - CEU; exam questions; pictorial; questions and answers; tables/charts. Note: For CE test see http://www.aornjournal.org/content/cme. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2018 SN - 0001-2092 SP - 86-94 ST - Clinical Issues—July 2018 T2 - AORN Journal TI - Clinical Issues—July 2018 UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=130399823&site=ehost-live&scope=site VL - 108 ID - 734 ER - TY - JOUR AB - This Month Operation of fluoroscopy equipment Key words: fluoroscopy, mini C-arm, scope of practice, radiologic device. Patient education after radionuclide implantation Key words: radionuclides, brachytherapy, prostate cancer, radiation safety. Personal protective equipment Key words: clean, decontamination, instruments, PPE, tray assembly. Safe staffing patterns Key words: on-call staffing, schedules, safe staffing levels. Counting instruments when laparoscopy procedures convert to open procedures Key words: counts, instrument, laparoscopy, retained surgical items. AN - 123814368. Language: English. Entry Date: 20170630. Revision Date: 20200324. Publication Type: Article. Journal Subset: Core Nursing AU - Ogg, Mary J. AU - Johnstone, Esther M. DB - ccm DO - 10.1016/j.aorn.2017.05.006 DP - EBSCOhost IS - 1 KW - Fluoroscopy Patient Education Brachytherapy Protective Devices Surgical Count Procedure Personnel Staffing and Scheduling N1 - Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2017 SN - 0001-2092 SP - 69-76 ST - Clinical Issues—July 2017 T2 - AORN Journal TI - Clinical Issues—July 2017 UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=123814368&site=ehost-live&scope=site VL - 106 ID - 745 ER - TY - JOUR AB - This Month Wearing ring dosimeters Key words: dosimeter, ring dosimeters, finger dosimeters. Reporting a retained surgical item (RSI) Key words: reportable event, retained surgical item, RSI, retained foreign object, counts. Definition of an implant Key words: implant, implant documentation . Determining whether RN first assistants (RNFAs) must maintain CNOR certification to practice Key words: CNOR, CRNFA, RNFA, first assistant, RN first assistant. Definition of personal protective equipment (PPE) Key words: personal protective equipment, PPE, surgical attire, removing PPE. AN - 116404438. Language: English. Entry Date: 20160728. Revision Date: 20200324. Publication Type: Article. Journal Subset: Core Nursing AU - Burlingame, Byron L. DB - ccm DO - 10.1016/j.aorn.2016.05.007 DP - EBSCOhost IS - 1 KW - Dosimetry Retained Instruments Prostheses and Implants RN First Assistants Perioperative Nursing Protective Clothing Documentation N1 - Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2016 SN - 0001-2092 SP - 71-78 ST - Clinical Issues—July 2016 T2 - AORN Journal TI - Clinical Issues—July 2016 UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=116404438&site=ehost-live&scope=site VL - 104 ID - 767 ER - TY - JOUR AB - This Month Use of count boards Key words: count, retained surgical item, RSI, count board, whiteboard, dry erase board . Subtracting items from the count Key words: count, retained surgical item, RSI, subtract, remove . Counting miscellaneous items for gynecological procedures Key words: count, retained surgical item, RSI, bulb syringe, cervical cup, vagina . RN first assistants (RNFAs) performing initial count Key words: count, retained surgical item, RSI, RNFA, first assistant . AD - Nursing Department at AORN, Inc, Denver, CO. AN - 112345534. Language: English. Entry Date: 20160121. Revision Date: 20160121. Publication Type: Article. Note: For CE see website. Journal Subset: Core Nursing AU - Wood, Amber DB - ccm DO - 10.1016/j.aorn.2015.10.020 DP - EBSCOhost IS - 1 KW - Surgical Count Procedure RN First Assistants Education, Continuing (Credit) AORN Surgical Sponges Surgery, Gynecologic Minimally Invasive Procedures N1 - Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2016 SN - 0001-2092 SP - 117-123 ST - Clinical Issues—January 2016 T2 - AORN Journal TI - Clinical Issues—January 2016 UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=112345534&site=ehost-live&scope=site VL - 103 ID - 768 ER - TY - JOUR AN - 128032344. Language: English. Entry Date: 20180223. Revision Date: 20191107. Publication Type: Article AU - Cahn, Julie AU - Wood, Amber DB - ccm DO - 10.1002/aorn.12061 DP - EBSCOhost IS - 2 KW - Fecal Microbiota Transplantation Zika Virus Infections Surgical Flaps Surgical Count Procedure Skin Preparation, Surgical Education, Continuing (Credit) Documentation Zika Virus Infections -- Prevention and Control Cross Infection -- Prevention and Control Perioperative Nursing Tissue Banks Retained Instruments -- Prevention and Control AORN Practice Guidelines Drug Hypersensitivity Iodine -- Adverse Effects Sutures Skull Antiinfective Agents, Local N1 - CEU; pictorial; questions and answers. Note: For CE see website. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2018 SN - 0001-2092 SP - 259-267 ST - Clinical Issues—February 2018 T2 - AORN Journal TI - Clinical Issues—February 2018 UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=128032344&site=ehost-live&scope=site VL - 107 ID - 743 ER - TY - JOUR AN - 133235633. Language: English. Entry Date: 20181130. Revision Date: 20181130. Publication Type: Article AU - Cahn, Julie DB - ccm DO - 10.1002/aorn.12438 DP - EBSCOhost IS - 6 KW - AORN Education, Nursing, Continuing Perioperative Nursing -- Standards Patient Safety -- Standards Education, Continuing (Credit) Nursing Practice, Evidence-Based Turnaround Time Cross Infection -- Prevention and Control Tattooing Health Personnel Hygiene Disabled -- Psychosocial Factors Wheelchairs Hospital Policies Organ Procurement -- Psychosocial Factors Surgical Count Procedure Equipment Contamination -- Prevention and Control Sterilization and Disinfection Infection Preventionists N1 - CEU; exam questions; pictorial; questions and answers. Note: For CE see http://www.aornjournal.org/content/cme. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Evidence-Based Practice. NLM UID: 0372403. PY - 2018 SN - 0001-2092 SP - 686-694 ST - Clinical Issues—December 2018 T2 - AORN Journal TI - Clinical Issues—December 2018 UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=133235633&site=ehost-live&scope=site VL - 108 ID - 720 ER - TY - JOUR AB - This Year Head coverings Key words: head cover, bouffant, skull cap, hair, scalp. Skin preps Key words: skin preps, antiseptics, cesarean delivery, surgical site infections, abdomen. Pediatric surgical counts Key words: pediatrics, counts, surgical, retained surgical items, policy. Sterile set up Key words: sterile table, sterile set up, covering, monitoring, contamination. Surgical hand antisepsis Key words: surgical hand rub, application, surgical scrub, scrubbed areas. AN - 119772317. Language: English. Entry Date: 20161130. Revision Date: 20161130. Publication Type: Article AU - Spruce, Lisa AU - Wood, Amber DB - ccm DO - 10.1016/j.aorn.2016.10.008 DP - EBSCOhost IS - 6 KW - Head Protective Devices Skin Preparation, Surgical Surgical Count Procedure -- In Infancy and Childhood Surgical Scrubbing Perioperative Nursing Education, Continuing (Credit) Child N1 - CEU. Note: For CE see website. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2016 SN - 0001-2092 SP - 593-600 ST - Clinical Issues—December 2016 T2 - AORN Journal TI - Clinical Issues—December 2016 UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=119772317&site=ehost-live&scope=site VL - 104 ID - 763 ER - TY - JOUR AN - 131051986. Language: English. Entry Date: 20180807. Revision Date: 20180807. Publication Type: Article AU - Ogg, Mary J. DB - ccm DO - 10.1002/aorn.12312 DP - EBSCOhost IS - 2 KW - Perioperative Nursing Nursing Practice Surgical Count Procedure Accidental Falls -- Prevention and Control Risk Assessment Physical Mobility -- Evaluation Functional Assessment Education, Continuing (Credit) Surgical Technologists Nursing Role Surgical Patients Nursing Assessment Accidental Falls -- Risk Factors Clinical Assessment Tools Practice Guidelines N1 - CEU; exam questions; pictorial; questions and answers. Note: For CE online Learner Evaluation see http://www.aornjournal.org/content/cme.. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Patient Safety. NLM UID: 0372403. PY - 2018 SN - 0001-2092 SP - 195-203 ST - Clinical Issues—August 2018 T2 - AORN Journal TI - Clinical Issues—August 2018 UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131051986&site=ehost-live&scope=site VL - 108 ID - 733 ER - TY - JOUR AN - 128766750. Language: English. Entry Date: 20180403. Revision Date: 20180403. Publication Type: Article AU - Johnstone, Esther M. DB - ccm DO - 10.1002/aorn.12113 DP - EBSCOhost IS - 4 KW - Skin Preparation, Surgical Infant Formula Product Evaluation Perioperative Nursing Surgical Count Procedure Education, Continuing (Credit) AORN Practice Guidelines N1 - CEU; exam questions; pictorial. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2018 SN - 0001-2092 SP - 510-516 ST - Clinical Issues—April 2018 T2 - AORN Journal TI - Clinical Issues—April 2018 UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=128766750&site=ehost-live&scope=site VL - 107 ID - 738 ER - TY - JOUR AB - Surgical counts during a partial cystectomy Key words: partial cystectomy, retained surgical item (RSI), counts, bladder, guidewire. Preparing the OR for patients who require both airborne and contact precautions Key words: airborne precautions, contact precautions, contamination, Coronavirus Disease 2019 (COVID-19), negative pressure. Preoperative transport of patients who require both airborne and contact precautions Key words: preoperative patient transport, hand hygiene, personal protective equipment (PPE), N95 respirator, Coronavirus Disease 2019 (COVID-19). Postoperative transport of patients who require both airborne and contact precautions Key words: postoperative patient transport, hand hygiene, personal protective equipment (PPE), N95 respirator, Coronavirus Disease 2019 (COVID-19). AN - 32857388 AU - Jones, E. AU - Wood, A. DA - Sep DO - 10.1002/aorn.13165 DP - NLM ET - 2020/08/29 IS - 3 LA - eng N1 - 1878-0369 Jones, Emily Wood, Amber Journal Article United States AORN J. 2020 Sep;112(3):291-300. doi: 10.1002/aorn.13165. PY - 2020 SN - 0001-2092 SP - 291-300 ST - Clinical Issues-September 2020 T2 - Aorn j TI - Clinical Issues-September 2020 VL - 112 ID - 259 ER - TY - JOUR AB - Using adhesive tape for patient positioning Key words: adhesive tape, surgical tape, patient positioning, pressure injury, contamination. Border sterility of open sterile wrappers Key words: wrapped sterile item, unsterile border, wrapper flap, contaminated, aseptic technique. Cost per minute of OR time Key words: cost comparison, direct costs, cost savings, perioperative efficiency, product evaluation. Packages containing an incorrect number of suture needles Key words: multipack, retained surgical item (RSI), counting, needle, package. AN - 33113195 AU - Seeman, K. DA - Nov DO - 10.1002/aorn.13238 DP - NLM ET - 2020/10/29 IS - 5 LA - eng N1 - 1878-0369 Seeman, Kristyn Journal Article United States AORN J. 2020 Nov;112(5):568-574. doi: 10.1002/aorn.13238. PY - 2020 SN - 0001-2092 SP - 568-574 ST - Clinical Issues-November 2020 T2 - Aorn j TI - Clinical Issues-November 2020 VL - 112 ID - 266 ER - TY - JOUR AB - Operation of fluoroscopy equipment Key words: fluoroscopy, mini C-arm, scope of practice, radiologic device. Patient education after radionuclide implantation Key words: radionuclides, brachytherapy, prostate cancer, radiation safety. Personal protective equipment Key words: clean, decontamination, instruments, PPE, tray assembly. Safe staffing patterns Key words: on-call staffing, schedules, safe staffing levels. Counting instruments when laparoscopy procedures convert to open procedures Key words: counts, instrument, laparoscopy, retained surgical items. AN - 28662788 AU - Ogg, M. J. AU - Johnstone, E. M. DA - Jul DO - 10.1016/j.aorn.2017.05.006 DP - NLM ET - 2017/07/01 IS - 1 LA - eng N1 - 1878-0369 Ogg, Mary J Johnstone, Esther M Journal Article United States AORN J. 2017 Jul;106(1):69-76. doi: 10.1016/j.aorn.2017.05.006. PY - 2017 SN - 0001-2092 SP - 69-76 ST - Clinical Issues-July 2017 T2 - Aorn j TI - Clinical Issues-July 2017 VL - 106 ID - 195 ER - TY - JOUR AB - Wearing ring dosimeters Key words: dosimeter, ring dosimeters, finger dosimeters. Reporting a retained surgical item (RSI) Key words: reportable event, retained surgical item, RSI, retained foreign object, counts. Definition of an implant Key words: implant, implant documentation. Determining whether RN first assistants (RNFAs) must maintain CNOR certification to practice Key words: CNOR, CRNFA, RNFA, first assistant, RN first assistant. Definition of personal protective equipment (PPE) Key words: personal protective equipment, PPE, surgical attire, removing PPE. AN - 27350357 AU - Burlingame, B. L. DA - Jul DO - 10.1016/j.aorn.2016.05.007 DP - NLM ET - 2016/06/29 IS - 1 LA - eng N1 - 1878-0369 Burlingame, Byron L Journal Article United States AORN J. 2016 Jul;104(1):71-8. doi: 10.1016/j.aorn.2016.05.007. PY - 2016 SN - 0001-2092 SP - 71-8 ST - Clinical Issues-July 2016 T2 - Aorn j TI - Clinical Issues-July 2016 VL - 104 ID - 179 ER - TY - JOUR AB - Head coverings Key words: head cover, bouffant, skull cap, hair, scalp. Skin preps Key words: skin preps, antiseptics, cesarean delivery, surgical site infections, abdomen. Pediatric surgical counts Key words: pediatrics, counts, surgical, retained surgical items, policy. Sterile set up Key words: sterile table, sterile set up, covering, monitoring, contamination. Surgical hand antisepsis Key words: surgical hand rub, application, surgical scrub, scrubbed areas. AN - 27890067 AU - Spruce, L. AU - Wood, A. DA - Dec DO - 10.1016/j.aorn.2016.10.008 DP - NLM ET - 2016/11/29 IS - 6 LA - eng N1 - 1878-0369 Spruce, Lisa Wood, Amber Journal Article United States AORN J. 2016 Dec;104(6):593-600. doi: 10.1016/j.aorn.2016.10.008. PY - 2016 SN - 0001-2092 SP - 593-600 ST - Clinical Issues-December 2016 T2 - Aorn j TI - Clinical Issues-December 2016 VL - 104 ID - 185 ER - TY - JOUR AN - 105201472. Language: English. Entry Date: 20100702. Revision Date: 20200708. Publication Type: Journal Article AU - Mitchell, S. DB - ccm DO - 10.1016/j.aorn.2010.02.008 DP - EBSCOhost IS - 5 KW - Casts Intraoperative Care Sterilization and Disinfection Surgical Count Procedure Education, Continuing (Credit) N1 - CEU; exam questions; questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2010 SN - 0001-2092 SP - 627-631 ST - Clinical issues T2 - AORN Journal TI - Clinical issues UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105201472&site=ehost-live&scope=site VL - 91 ID - 778 ER - TY - JOUR AN - 105406823. Language: English. Entry Date: 20091009. Revision Date: 20150818. Publication Type: Journal Article AU - Mitchell, S. DB - ccm DP - EBSCOhost IS - 2 KW - Documentation Sterilization and Disinfection -- Standards Surgical Count Procedure Surgical Instruments N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PY - 2009 SN - 0001-2092 SP - 279-282 ST - Clinical issues T2 - AORN Journal TI - Clinical issues UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105406823&site=ehost-live&scope=site VL - 90 ID - 789 ER - TY - JOUR AD - PERIOPERATIVE NURSING SPECIALIST, AORN NURSING DEPARTMENT AN - 104187820. Language: English. Entry Date: 20130702. Revision Date: 20200708. Publication Type: Journal Article AU - Denholm, Bonnie DB - ccm DO - 10.1016/j.aorn.2013.05.002 DP - EBSCOhost IS - 1 KW - Perioperative Care Perioperative Nursing -- Standards Patient Safety Nursing Role Medical Waste Disposal Environment Drugs Surgical Equipment and Supplies Sterilization and Disinfection Asepsis Documentation Checklists Wrong Site Surgery Health Care Errors Surgical Count Procedure Education, Continuing (Credit) N1 - CEU; exam questions; questions and answers; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 0372403. PMID: NLM23806598. PY - 2013 SN - 0001-2092 SP - 81-90 ST - Clinical Issues T2 - AORN Journal TI - Clinical Issues UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104187820&site=ehost-live&scope=site VL - 98 ID - 740 ER - TY - JOUR AD - Clinical Manager, OR, Doylestown Hospital, Doylestown, PA AN - 107045923. Language: English. Entry Date: 20010824. Revision Date: 20150818. Publication Type: Journal Article AU - Barrow, C. J. DB - ccm DO - 10.1016/S0001-2092(06)61120-4 DP - EBSCOhost IS - 1 KW - Surgical Count Procedure Radiography Needles Hospital Policies Data Collection N1 - diagnostic images. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PMID: NLM11460785. PY - 2001 SN - 0001-2092 SP - 80-81 ST - Clinical innovations. Use of x-ray in the presence of an incorrect needle count T2 - AORN Journal TI - Clinical innovations. Use of x-ray in the presence of an incorrect needle count UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107045923&site=ehost-live&scope=site VL - 74 ID - 919 ER - TY - JOUR AB - Triplex (Terumo Co., Tokyo, Japan), a newly developed large diameter vascular graft sealed with a non-biodegradable material, is expected to reduce inflammatory reaction. We confirmed its safe implantation and assessed inflammatory reaction after thoracic aortic surgery. Between January 2009 and February 2010, 101 consecutive patients underwent thoracic aortic replacement. Triplex grafts were implanted in 40 patients, and bovine-collagen coated grafts (Hemashield, Boston Scientific, Boston, MA, USA) were implanted in 61 patients. During the postoperative course, body temperature and laboratory findings including inflammatory markers were examined. The mean operation time and amount of bleeding during operation were equivalent in the two groups. The mean body temperature and Creactive protein in patients implanted with Triplex were significantly lower than those in patients implanted with Hemashield grafts. The mean white blood cell count tended to be at lower levels in patients implanted with Triplex grafts. No patients in both groups suffered postoperative complications associated with the prosthetic grafts. Triplex was confirmed to be safely applied for thoracic aortic surgery as well as the conventional vascular grafts and to reduce postoperative inflammatory reaction. © 2011 Published by European Association for Cardio-Thoracic Surgery. All rights reserved. AD - Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma, Omiya-ku, Saitama City, Saitama 330-8503, Japan AU - Tamura, A. AU - Yamaguchi, A. AU - Yuri, K. AU - Noguchi, K. AU - Naito, K. AU - Nagano, H. AU - Takahashi, M. AU - Adachi, H. DB - Scopus DO - 10.1510/icvts.2010.262022 IS - 5 KW - Inflammatory reaction Non-biodegradable material Triplex graft M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2011 SP - 758-761 ST - Clinical experience with a new vascular graft free from biodegradable material T2 - Interactive Cardiovascular and Thoracic Surgery TI - Clinical experience with a new vascular graft free from biodegradable material UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79956198094&doi=10.1510%2ficvts.2010.262022&partnerID=40&md5=fee04ca4424d3ac6a832d026a96454ec VL - 12 ID - 1422 ER - TY - JOUR AB - Introduction & Objective: To analyze the safety and efficacy of pipe extractor of improved collar style and traditional foreign body forceps in the extubation of the double-J stent. Materials and Methods: A total of 120 cases, who underwent extubated the double-J stent by urethral cystoscopy from September 2013 to August 2014, were randomly divided into two groups, 60 of which underwent pipe extractor of improved collar style and the other 60 patients underwent traditional foreign body forceps. The difference of operation time, the numeric rating scale (NRS) of operation, the numeric rating scale (NRS) of the 10 minutes after operation, the number of patients of gross hematuria after operation between the two groups were compared and analyzed. Results: The numeric rating scale (NRS) of operation, the numeric rating scale (NRS) of the 10 minutes after operation, the number of patients of gross hematuria, red blood cell count after operation of pipe extractor of improved collar style and traditional foreign body forceps were (4.9 ± 1.6) scores and (6.9 ± 0.9) scores, (1.7 ± 1.0) scores and (3.1 ± 0.7) scores, (41/60) (68.3%) and (51/60) (85.0%), (38.9 ± 13.7)/μl and (89.5 ± 26.6)/μl, respectively. There were statistical significance between the two groups (P < 0.05). The operation time was (65.1 ± 12.1) s and (63.6 ± 17.8) s, there was not statistical significance between the two groups (P > 0.05). Conclusions: Relative to the traditional foreign body forceps, the self-designed pipe extractor of improved collar style in the extubation of the double-J stent is simple and little injury, which is worth to recommand its clinical use. (Figure presented). AU - Gu, J. AU - Zhang, Y. AU - Li, J. AU - Zhao, Q. DB - Embase DO - 10.1089/end.2016.29020.abstracts KW - controlled clinical trial controlled study cystoscopy double J stent erythrocyte count extubation forceps foreign body hematuria human major clinical study operation duration randomized controlled trial rating scale statistical significance urethra LA - English M3 - Conference Abstract N1 - L613823989 2016-12-27 PY - 2016 SN - 1557-900X SP - A153-A154 ST - Clinical curative effect comparison of pipe extractor of improved collar style and traditional foreign body forceps in the extubation of the double-J stent T2 - Journal of Endourology TI - Clinical curative effect comparison of pipe extractor of improved collar style and traditional foreign body forceps in the extubation of the double-J stent UR - https://www.embase.com/search/results?subaction=viewrecord&id=L613823989&from=export http://dx.doi.org/10.1089/end.2016.29020.abstracts VL - 30 ID - 419 ER - TY - JOUR AB - Introduction: Staphylococci is the most commonly isolated bacteria in blood cultures (BC), and is mostly regarded as contamination. However, the clinical relevance and characteristics of CNS other than Staphylococcus epidermidis (Non-SE-CNS) is still unknown. Methods: For the purpose of clarifying the epidemiology and clinical significance of Non-Se-CNS infections, we retrospectively evaluated BC isolates of Non-Se-CNS at our institute from May 2013 to March 2017. Infections were defined as true bacteremia if (1) two or more positive BCs of the same species were present (or detection of the same species in another clinically relevant sample), (2) the patient had clinical symptoms as outlined in the Centers for Disease Control and Prevention's definition of primary blood stream infection8 and the symptoms or markers of inflammation (e.g., fever, symptoms, white cell counts, C-reactive protein, or procalcitonin) were improved after pathogen-directed therapy (e.g. either antibiotic therapy and/or removal of the foreign body in the case of catheter-related blood stream infections suspected) and (3) without any other infection. Results: During the period, 279 patients with BC positive for Non Se–CNS were identified. 44 patients were excluded, either due to missing data or multiple pathogens in the same BC. Among the remaining 235 patients, 67 (29%) were categorized as true bacteremia (n = 43) or possible infections (n = 24). Resistance rate to methicillin among Non-SE-CNS is about 60%, which is lower than those among S. epidermidis of 78%. Conclusion: About 30% of Non-Se-CNS isolates were clinically relevant in our study. Antibiotic susceptibility of Non-SE-CNS is quite different than those of S. epidermidis. AD - H. Mikamo, Department of Clinical Infectious Diseases, Aichi Medical University School of Medicine, 1-1 Yazakokarimata, Nagakute, Aichi, Japan AU - Asai, N. AU - Sakanashi, D. AU - Suematsu, H. AU - Kato, H. AU - Hagihara, M. AU - Watanabe, H. AU - Shiota, A. AU - Koizumi, Y. AU - Yamagishi, Y. AU - Mikamo, H. DB - Embase Medline DO - 10.1016/j.jmii.2020.03.001 KW - adult adverse device effect antibiotic sensitivity antibiotic therapy article bacteremia blood culture catheter infection central nervous system infection clinical feature coagulase negative Staphylococcus contamination controlled study disease control female fever foreign body human infectious agent leukocyte count major clinical study male nonhuman prevention retrospective study surgery C reactive protein endogenous compound meticillin procalcitonin LA - English M3 - Article in Press N1 - L2005565436 2020-04-20 PY - 2020 SN - 1995-9133 1684-1182 ST - Clinical characteristics and relevance of coagulase-negative Staphylococci other than S. epidermidis by positive blood culture T2 - Journal of Microbiology, Immunology and Infection TI - Clinical characteristics and relevance of coagulase-negative Staphylococci other than S. epidermidis by positive blood culture UR - https://www.embase.com/search/results?subaction=viewrecord&id=L2005565436&from=export http://dx.doi.org/10.1016/j.jmii.2020.03.001 ID - 293 ER - TY - JOUR AB - BACKGROUND: A study was performed to investigate histological changes in capsules formed around silicone breast implants and their correlation with the clinical classification of capsular contracture defined by the Baker score. For histological classification, the authors used the classification introduced by Wilflingseder, which identifies four grades of contracture. METHODS: The study included 24 female patients (average age, 40 ± 12 years) with capsular contracture after bilateral cosmetic breast augmentation with smooth silicone gel implants (Mentor, Santa Barbara, Calif.). The Baker score was determined preoperatively for each patient. Samples of capsular tissue were obtained from all patients for histologic and immunohistochemical analyses. Capsular thickness, age of the collagen fibers, presence of synovia-like metaplasia on the inner surface of the capsule, number of histiocytes, giant cells, and other inflammatory cells, amount of silicone, foreign body granulomas, and capsule calcification were evaluated. RESULTS: There was a positive correlation between capsular thickness (p < 0.05) and Baker score. Silicone-containing deposits were found in all four histological capsule types. A trend toward greater capsular thickness was documented in patients with severe inflammatory reaction. These patients also had more clinical symptoms. Greater capsular thickness was associated with a higher number of silicone particles and silicone-loaded macrophages in the peri-implant capsule. CONCLUSIONS: The authors demonstrated a positive correlation (p < 0.05) between the clinical classification (Baker score I to IV) and the histological classification introduced by Wilflingseder (Wilflingseder score I to IV). An exact histological classification is needed to describe precisely the morphological changes in capsular contracture. ©2007American Society of Plastic Surgeons. AD - Department of Plastic Surgery, University Hospital Regensburg, Regensburg, Germany Department of Plastic Surgery, University of Regensburg, Franz-Josef-Strauß-Allee 11, G-93042 Regensburg, Germany AU - Prantl, L. AU - Schreml, S. AU - Fichtner-Feigl, S. AU - Pöppl, N. AU - Eisenmann-Klein, M. AU - Schwarze, H. AU - Füchtmeier, B. DB - Scopus DO - 10.1097/01.prs.0000264398.85652.9a IS - 1 M3 - Article N1 - Cited By :102 Export Date: 10 November 2020 PY - 2007 SP - 275-284 ST - Clinical and morphological conditions in capsular contracture formed around silicone breast implants T2 - Plastic and Reconstructive Surgery TI - Clinical and morphological conditions in capsular contracture formed around silicone breast implants UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-34250696592&doi=10.1097%2f01.prs.0000264398.85652.9a&partnerID=40&md5=a0276ff4b69ec98802ec201cec5c138c VL - 120 ID - 1562 ER - TY - JOUR AB - Denture impacted in the esophagus of adults has been a complex foreign body for otolaryngologists. We reviewed clinical characteristics, diagnosis, and treatment of these patients and evaluated computed tomography (CT) scans to identify a better method of dealing with such tricky situations. Twenty-nine patients who underwent rigid esophagoscopy were included in this retrospective study conducted at the University hospital. The patients underwent preoperative tests and examinations, including complete blood count, blood type and coagulation, electrocardiogram, and CT. The commonest symptoms were retrosternal pain, dysphagia, and odynophagia. Duration of the foreign body impacted within 24 h was 65.5%. CT findings revealed that 4 of 24 cases had complications in the upper esophagus, with 3 of the 4 cases in the mid-esophagus and 1 in the lower esophagus. Complications were related to the duration and location of the obstruction (P < 0.05). The location and complications based on CT findings were coherent with rigid esophagoscopy findings. Denture impaction in the esophagus can be fatal. Early intervention is crucial for prognosis. CT is used for diagnosing and guiding doctors in managing. The commonest location of impacted dentures was the upper esophagus with a lower incidence of complications. The incidence of an impacted denture in the mid-esophagus was low but with a high risk of complications. The incidence of an impacted denture in the lower esophagus was rare. Surgery and proper treatment ensure a good prognosis. AD - Department of Otorhinolaryngology, The First Hospital of China Medical University, 155, Nanjing North Street, Heping District, Shenyang, Liaoning Province, China. Department of Otorhinolaryngology, The First Hospital of China Medical University, 155, Nanjing North Street, Heping District, Shenyang, Liaoning Province, China. 37727704@qq.com. AN - 31463803 AU - Wang, F. AU - Yang, N. AU - Wang, Z. AU - Guo, X. AU - Hui, L. DA - Jun DO - 10.1007/s00455-019-10048-3 DP - NLM ET - 2019/08/30 IS - 3 KW - *Computed tomography (CT) *Deglutition *Deglutition disorders *Dentures *Foreign body *Rigid esophagoscopy LA - eng N1 - 1432-0460 Wang, Fei Yang, Ning Wang, Zheng Guo, Xing Hui, Lian Journal Article United States Dysphagia. 2020 Jun;35(3):455-459. doi: 10.1007/s00455-019-10048-3. Epub 2019 Aug 28. PY - 2020 SN - 0179-051x SP - 455-459 ST - Clinical Analysis of Denture Impaction in the Esophagus of Adults T2 - Dysphagia TI - Clinical Analysis of Denture Impaction in the Esophagus of Adults VL - 35 ID - 234 ER - TY - JOUR AB - Nursing surveillance, an essential component of perioperative practice, includes the detection of and recovery from errors. However, error recovery is considered routine during nursing care and may go under-recognized. This study assessed the types of errors or potential errors that were detected and recovered by the circulating nurse during care of patients undergoing coronary artery or valve surgery. From June to September 2010, perioperative nurses observed 18 surgical procedures. An average of 11.11 errors or incidents occurred per procedure; however, 77% of all incidents were intercepted and the other 23% were either mitigated or ameliorated so no adverse outcomes occurred. This study demonstrates that nurses play an important role in ensuring patient safety and reinforces the necessity of vigilance in the OR, especially in regard to aseptic technique and surgical prepping. AN - 104462278. Language: English. Entry Date: 20120720. Revision Date: 20200708. Publication Type: Journal Article AU - Yang, Y. Tony AU - Henry, Linda AU - Dellinger, Mary AU - Yonish, Kersten AU - Emerson, Brett AU - Seifert, Patricia C. DB - ccm DO - 10.1016/j.aorn.2011.09.022 DP - EBSCOhost IS - 6 KW - Heart Surgery Nursing Role Perioperative Nursing Treatment Errors -- Prevention and Control Funding Source Human Information Resources Nurses Observational Methods Patient Safety Skin Preparation, Surgical Surgical Count Procedure Virginia World Wide Web N1 - research; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Perioperative Care. Grant Information: This study was funded by a research grant partnership between Inova Health Systems and George Mason University and partially supported by an Inova Health Systems Nursing Research Fellowship Grant.. NLM UID: 0372403. PMID: NLM22633382. PY - 2012 SN - 0001-2092 SP - 755-762 ST - The Circulating Nurse's Role in Error Recovery in the Cardiovascular OR T2 - AORN Journal TI - The Circulating Nurse's Role in Error Recovery in the Cardiovascular OR UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104462278&site=ehost-live&scope=site VL - 95 ID - 752 ER - TY - JOUR AB - Purpose: Background: Chylous ascites has been associated with AIDS however only in a rare report of Mycobacterium avium complex (MAC) infection. Case Report: A 37-year-old male presented with abdominal pain and distension over one week. Past medical history was significant for AIDS and disseminated MAC diagnosed two years prior. He denied a history of liver disease, alcohol or drug use. He recently started Highly Active Anti-Retroviral Therapy (HAART) and over the last nine months increased his CD4 count from 11 ccm to 230 ccm. On admission he was hemodynamically-stable however was noted to be tachypneic. Physical exam was significant for shift ing dullness suggesting ascites and inguinal lymphadenopathy bilaterally. Initial blood work was normal, but CT of the abdomen showed a soft -tissue mass at the base of the small bowel mesentery with areas of central low attenuation. This lymph node conglomeration measured approximately 7.0 × 4.6 cm and encased several vessels exerting moderate masseffect. Also, jejunal wall thickening surrounded the mass which can be a nonspecific finding for MAC. Abdominal paracentesis was performed revealing a milky ascitic fluid with a white blood cell count of 1078/uL, triglyceride level of 245 mg/dL, total protein of 2.4 g/dL, lactate dehydrogenase of 257 U/L and glucose of 86 mg/dL. While initial fluid culture returned negative for MAC, biopsy of the mesenteric lymph nodes found granulomatous inflammation with epithelioid cells, histiocytes and foreign body giant cells. These changes have been reported as pathognomonic for MAC. As no adenopathy or splenomegaly was found by imaging, lymphoma was of low suspicion and Immune Reconstitution Inflammatory Syndrome (IRIS) associated with known history of MAC was substantiated. Thus, treatment for suspected MAC infection with azithromycin was started which resulted in an improvement of his abdominal pain and distention. Conclusion: IRIS is commonly seen in AIDS patients after HAART therapy is started. As the immune system recovers, it may cause an overwhelming inflammatory response to prior infections. Thus, recognition of IRIS in an AIDS patient presenting with new onset ascites may facilitate early diagnosis and treatment of opportunistic infections. (Figure presented). AD - D. Beyda, Beth Israel Medical Center, Manhattan, NY, United States AU - Beyda, D. AU - Korman, A. AU - Hudesman, D. AU - Favila, K. AU - Horowitz, M. AU - Bernstein, B. DB - Embase DO - 10.1038/ajg.2010.320-7 KW - CD4 antigen glucose protein triacylglycerol azithromycin lactate dehydrogenase AIDS patient human chylous ascites atypical mycobacteriosis college gastroenterology acquired immune deficiency syndrome infection lymphadenopathy therapy abdominal pain ascites paracentesis lymph node attenuation male mesentery small intestine histiocyte lymphoma immune reconstitution inflammatory syndrome ascites fluid leukocyte count drug use soft tissue mesentery lymph node abdomen alcohol liver disease biopsy liquid granulomatous inflammation epithelioid cell blood giant cell splenomegaly imaging immune system inflammation early diagnosis opportunistic infection medical history case report highly active antiretroviral therapy LA - English M3 - Conference Abstract N1 - L70825457 2012-08-10 PY - 2010 SN - 0002-9270 SP - S230 ST - Chylous ascites in an AIDS patient with a history of mycobacterium avium complex infection T2 - American Journal of Gastroenterology TI - Chylous ascites in an AIDS patient with a history of mycobacterium avium complex infection UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70825457&from=export http://dx.doi.org/10.1038/ajg.2010.320-7 VL - 105 ID - 555 ER - TY - JOUR AB - We report on a patient who underwent total vaginal hysterectomy for urinary incontinence 8 years previously with a sling operation using transobturator tape (TOT). She was admitted to our hospital after complaints of vaginal discharge, foul odor, and bleeding, left thigh pain, and edema. Magnetic resonance imaging (MRI) and computed tomography (CT) revealed a fistula tract fromthe vagina or urethra with remnant sling tape. We removed the remnant tape using intraoperative ultrasonography. This case exemplifies the rare occurrence of a vaginal fistula extending to the obturator, adductor, and pectineus muscles combined with myositis after TOT placement. It is important that urogynecologists recognize that TOT procedures may result in complications accompanied by common recurrent vaginal symptoms, such as vaginal odor and spotting, which can be identified by MRI or CT. © The International Urogynecological Association 2013. AD - Department of Obstetrics and Gynecology, Soonchunhyang University College of Medicine, Bucheon 420-767, South Korea Department of Urology, Soonchunhyang University College of Medicine, Bucheon 420-767, South Korea Department of Urology, Soonchunhyang University Bucheon Hospital, 170 Jomaru-ro, Wonmi-gu, Bucheon-si, Gyunggi-do 420-767, South Korea AU - Kim, T. H. AU - Lee, H. H. AU - Kim, J. M. DB - Scopus DO - 10.1007/s00192-013-2232-6 IS - 5 KW - Mesh exposure Transobturator tape Vagina fistula M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2014 SP - 695-697 ST - Chronic vaginal discharge and left leg edema after a transobturator tape procedure T2 - International Urogynecology Journal and Pelvic Floor Dysfunction TI - Chronic vaginal discharge and left leg edema after a transobturator tape procedure UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84905512023&doi=10.1007%2fs00192-013-2232-6&partnerID=40&md5=eadb0f2218a9bc2e1999254238a6a2b0 VL - 25 ID - 1297 ER - TY - JOUR AN - 107930690. Language: English. Entry Date: 20131008. Revision Date: 20150820. Publication Type: Journal Article DB - ccm DO - 10.1097/01.NURSE.0000434318.83194.41 DP - EBSCOhost IS - 10 KW - Operating Rooms Treatment Errors -- Prevention and Control Risk Management Checklists Surgical Equipment and Supplies Surgical Count Procedure N1 - brief item; pictorial. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Special Interest: Patient Safety; Perioperative Care; Quality Assurance. NLM UID: 7600137. PY - 2013 SN - 0360-4039 SP - 17-17 ST - Checklists reduce errors by nearly 50% T2 - Nursing TI - Checklists reduce errors by nearly 50% UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107930690&site=ehost-live&scope=site VL - 43 ID - 900 ER - TY - JOUR AB - Objectives: The macrophage is typically the predominant cell type in the foreign body response. In a recent study, T cells were almost as prevalent as mac-rophages in the cellular infiltrate surrounding polypropylene mesh fibers in a nonhuman primate model. It is well documented that T lymphocytes play a prominent role in the progression of pathologic tissue fibrosis. We aimed to further characterize the T cell response to vaginal mesh in the context of the overall foreign body response. Methods: Patients scheduled to undergo surgical excision of a mid-urethral sling for the complaint of pain vs. exposure were offered enrollment. 25 mesh-vaginal tissue complexes (exposure, n= 14; pain n= 11) were compared to 8 full thickness vaginal biopsies taken at the time of mesh excision from an uninvolved area on the anterior vaginal wall (control). Identification of T lymphocyte subsets was performed with immunofluorescent labeling. Tissue sections were quadruple-labeled for CD4+ (T helper), CD8 (cytotoxic T), Foxp3 (regulatory T cells) and nuclear marker DAPI. Six 200x images were taken from control tissue and two representative areas of mesh-tissue interface using a Nikon Eclipse 90i Imaging Microscope. Total numbers of cells were counted along with the number of cells that co-labeled with CD4, CD8 and Foxp3. A one-way ANOVA was performed with Tukey post hoc testing for multivariate analysis. Results: Demographics including age, BMI, parity, smoking history, meno-pausal status, hormone use and average time of mesh implantation did not differ between groups. Mesh-tissue complexes demonstrated a marked, but highly localized foreign body response similar to what has been described. We consistently observed a teardrop shaped fibroma encapsulating mesh fibers in both pain and exposure groups, with the T cells localized within the “cap”of this configuration away from the mesh-tissue interface. This is in contrast to the localization pattern of macrophages, which is limited to the area immediately surrounding mesh fibers. We found significantly more CD4+ (T helper) cells in both mesh groups (pain, p= 0.03; and exposure, p= 0.04) compared to controls. We also found more Foxp3+ (Tregs)in the exposure group comparedto controls (p= 0.02) but not in the pain group compared to controls (0.36). We did not find significant differences between the numbers of CD8+ (cytotoxic T) cells in either the pain (p= 0.86) or exposure group (p= 0.88) vs controls. When comparing the pain and exposure groups, we did not find significant differences between any of the T cell subtypes. On paired analysis there were significantly greater CD4+, CD8+, Foxp3+ and total number of cells in the mesh-tissue complexes compared to their controls (p=.0005, p=.01, p=.001 and p=.002, respectively.) Conclusions: T cells are present within a highly specific distribution area around vaginal mesh fibers explanted from women with complications. The complexity of the T cell response as it relates to mesh complications is not well understood but may be a central pathway with differing clinical presentations. Further research examining how T lymphocytes influence human response to vaginal mesh will broaden our understanding of mesh biology and clinical outcomes. AD - L. Tennyson, Department of Urology, UPMC, Pittsburgh, PA, United States AU - Tennyson, L. AU - Palcsey, S. AU - Abramowitch, S. D. AU - Moalli, P. A. DB - Embase DO - 10.1097/SPV.0000000000000477 IS - 5 KW - CD4 antigen CD8 antigen endogenous compound hormone transcription factor FOXP3 adult analysis of variance biology biopsy body mass cell population clinical article clinical outcome complication controlled study cytotoxic T lymphocyte excision female fiber fibroma foreign body helper cell human human cell human tissue immunofluorescence implantation macrophage multivariate analysis outcome assessment pain parity regulatory T lymphocyte smoking suburethral sling T lymphocyte subpopulation thickness tissue section vagina tissue LA - English M3 - Conference Abstract N1 - L618367242 2017-09-26 PY - 2017 SN - 2154-4212 SP - S36 ST - Characterization of the T cell population in vaginal mesh removed from women with complications T2 - Female Pelvic Medicine and Reconstructive Surgery TI - Characterization of the T cell population in vaginal mesh removed from women with complications UR - https://www.embase.com/search/results?subaction=viewrecord&id=L618367242&from=export http://dx.doi.org/10.1097/SPV.0000000000000477 VL - 23 ID - 367 ER - TY - JOUR AB - Photopolymerizable poly(ethylene glycol) (PEG)-based hydrogels have great potential as in vivo cell delivery vehicles for tissue engineering. However, their success in vivo will be dependent on the host response. The objectives for this study were to explore the in vivo host response and in vitro macrophage response to commonly used PEG-based hydrogels, PEG and PEG containing RGD. Acellular hydrogels were implanted subcutaneously into c57bl/6 mice and the foreign body response (FBR) was compared to medical grade silicone. Our findings demonstrated PEG-RGD hydrogels resulted in a FBR similar to silicone, while PEG-only hydrogels resulted in a robust inflammatory reaction characterized by a thick layer of macrophages at the material surface with evidence of gel degradation. In vitro, bone marrow-derived primary macrophages adhered well and similarly to PEG-based hydrogels, silicone, and tissue culture polystyrene when cultured for 4 days. Significantly higher gene expressions of the proinflammatory cytokines, TNF-a and Il-1b, were found in macrophages seeded onto PEG compared to PEG-RGD and silicone at 1 and 2 days. PEG hydrogels were also shown to be susceptible to oxidative biodegradation. Our findings indicate that PEG-only hydrogels are proinflammatory while RGD attenuates this negative reaction leading to a moderate FBR. © 2009 Wiley Periodicals, Inc. AD - Department of Chemical and Biological Engineering, University of Colorado, Boulder, CO 80309-0424, United States Department of Pathology, Yale University School of Medicine, New Haven, CT 066536-0812, United States AU - Lynn, A. D. AU - Kyriakides, T. R. AU - Bryant, S. J. DB - Scopus DO - 10.1002/jbm.a.32595 IS - 3 KW - In vivo Inflammation Macrophage Murine Poly(ethylene glycol) M3 - Article N1 - Cited By :97 Export Date: 10 November 2020 PY - 2010 SP - 941-953 ST - Characterization of the in vitro macrophage response and in vivo host response to poly(ethylene glycol)-based hydrogels T2 - Journal of Biomedical Materials Research - Part A TI - Characterization of the in vitro macrophage response and in vivo host response to poly(ethylene glycol)-based hydrogels UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77950675704&doi=10.1002%2fjbm.a.32595&partnerID=40&md5=b85bd74b69fe4588af0470b73d4aa805 VL - 93 ID - 1457 ER - TY - JOUR AB - Purpose : According to the United States Eye Injury Registry, gunshot wounds (GSW) to the eye account for approximately 6.5% of ocular trauma injuries. While studies have been conducted on gun-related eye injuries, none have concentrated on gunshot-related open globes in a civilian setting. Our aim is to describe the characteristics and outcomes of open globes secondary to GSW. Methods : A retrospective chart review was performed on patients with open globe injuries secondary to GSW at Memorial Hermann Hospital-Texas Medical Center between January 2010 and March 2015. Patient demographics, cause of GSW, gunshot injury characteristics, ocular signs and concurrent injuries, location of injury, evisceration/enucleation performed, and final visual acuity (VA) were recorded. Results : Of 480 open globes, 16 were due to GSW (3.3%). The majority were sustained by males (12 [75%]) and adults (≥18 years; 12 [75%]), with mean age 28.4 years (±17.1, range 1-74). Causes of gun trauma were accidental (6 [38%]), assault (5 [31%]), self-inflicted (4 [25%]), and unknown (1 [6%]). All except 1 were zone 3 injuries. The majority sustained other ocular injuries, including orbital wall fractures (63%), lid lacerations (50%), and hyphema (63%). Four patients (25%) sustained canalicular lacerations. Nine (56%) and 5 (31%) eyes had orbital and intraocular foreign bodies, respectively. Six of the 10 (60%) patients with GSWs who were able to participate in VA testing at initial consultation had no light perception vision. Of the rest, 2 were hand motion, 1 was light perception, and 1 was 20/200. Ten (63%) open globes underwent surgical repair within 24 hours, 3 (19%) in 24 - 48 hours, and 3 (19%) after 48 hours. Eleven (69%) eyes required an enucleation/evisceration. After surgical repair, 12 (79%) eyes had a final VA of NLP, 1 (6%) eye was HM and 3 (19%) eyes had final VA better than counting fingers. These 3 were all shotgun injuries, of which 2 were accidental and 1 from assault. Conclusions : The great majority of open globe injuries secondary to GSW have a poor visual outcome with most suffering unsalvageable damage resulting in evisceration or enucleation. The poor visual prognosis may be explained by the majority sustaining zone 3 injuries, which by nature are typically irreversible. Larger studies are needed to better understand these injuries and prevent their occurrence. AD - H.M. Castro, Ruiz Department of Ophthalmology and Visual Science, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, United States AU - Castro, H. M. AU - Gross, A. AU - Chuang, A. AU - Mankiewicz, K. A. AU - Richani, K. AU - Crowell, E. L. DB - Embase IS - 7 KW - adult assault case report clinical article conference abstract consultation demography emergency health service evisceration eye injury finger fracture gunshot injury human hyphema intraocular foreign body laceration male medical record review motion prognosis retrospective study Texas vision visual acuity LA - English M3 - Conference Abstract N1 - L632695292 2020-09-02 PY - 2020 SN - 1552-5783 ST - Characteristics of open globes secondary to gunshot wounds presenting at a level 1 trauma center T2 - Investigative Ophthalmology and Visual Science TI - Characteristics of open globes secondary to gunshot wounds presenting at a level 1 trauma center UR - https://www.embase.com/search/results?subaction=viewrecord&id=L632695292&from=export VL - 61 ID - 300 ER - TY - JOUR AB - Purpose To describe the demographics, outcomes, and posterior segment (PS) complications in eyes with PS intraocular foreign bodies (IOFBs) that presented to University Hospital in Newark, NJ between 2004 and March 2013. Methods Retrospective chart review. Results Of the 65 eyes identified with IOFBs, 30 had IOFBs in the PS only, 4 had IOFBs in both segments. The average age of patients was 37.8 years (range 20-63). Thirty-one IOFBs (91%) were metal, 2 glass (6%), and 1 plastic (3%). The size of IOFBs ranged from <1 to 24mm, with 21(62%) being 1-5 mm. Diagnosis was made by clinical exam, B-scan, and/or CT scans. Pre-operative visual acuity (VA) ranged from count fingers (CF) to 20/20, an average of 20/462. Final VA ranged from CF to 20/25, an average of 20/204. Twenty-six IOFBs (77%) were removed through surgical sclerotomies. All 34 eyes underwent open globe repair (OGR) within 24 hours of presentation; 30 underwent concurrent pars plana vitrectomy (PPV). The mean duration between time of injury and OGR was 2.35 days. IOFBs were removed from 32 (97%) eyes at the primary repair; in two cases, the PS IOFBs were not seen initially but noted on follow up B scan and CT scan, respectively. Five of 34 eyes received intravitreal antibiotics, Vancomycin and Ceftazidime, at OGR. All patients were given IV antibiotics for an average of 3.90 days. Twenty-four (71%) eyes presented with cataracts, 22 were left aphakic after pars plana lensectomy (PPL) with OGR. At presentation, 26 of 34 (77%) eyes had vitreous hemorrhage, 19 (56%) retinal detachment (RD), 1 (3%) hemorrhagic choroidals and 2 (6%) with endophthalmitis. Eleven eyes were noted to have retinal tears (without RD) intra-operatively. Eighteen of 19 eyes (95%) with RD underwent RD repair (RDR) at presentation (1 eye had RDR one week later). Six of 19(32%) underwent silicone oil tamponade, 14 (41%) endolaser photocoagulation, 9 (47%) gas tamponade, and 3 (9%) scleral buckle procedure. Two eyes were lost to follow-up. Anatomic success of after one RDR was 33% (6/17). Eleven of 17 (65%) eyes had recurrent RD with proliferative vitreoretinopathy (PVR). The overall anatomic success was 94% (16/17). Conclusions Posterior segment IOFBs are associated with vitreous hemorrhage, retinal tears and RDs. Overall anatomic success of retinal reattachment in patients was 94% in our series. AD - P. Misra, Institute of Ophthalmology and Visual Science, Newark, NJ, United States AU - Misra, P. AU - Abbassi, S. M. AU - Bauza, A. AU - Zarbin, M. AU - Bhagat, N. DB - Embase IS - 13 KW - ceftazidime silicone oil vancomycin adult B scan cataract choroid clinical article diagnosis endolaser endophthalmitis female finger follow up human intraocular foreign body laser coagulation lensectomy male pars plana vitrectomy retina detachment surgery retina tear scleral buckle sclerotomy surgery visual acuity vitreoretinopathy vitreous hemorrhage x-ray computed tomography LA - English M3 - Conference Abstract N1 - L616122663 2017-05-16 PY - 2014 SN - 0146-0404 SP - 5475 ST - Characteristics and demographics of patients with posterior segment intraocular foreign bodies T2 - Investigative Ophthalmology and Visual Science TI - Characteristics and demographics of patients with posterior segment intraocular foreign bodies UR - https://www.embase.com/search/results?subaction=viewrecord&id=L616122663&from=export VL - 55 ID - 448 ER - TY - JOUR AB - Infections related to implanted medical devices have become a significant health care issue in recent decades. Increasing numbers of medical devices are in use, often in an aging population, and these devices are implanted against a background of increasing antibiotic-resistant bacterial populations. Progressively more antibiotic resistant infections, requiring ever more refined treatment options, are therefore predicted to emerge with greater frequency in the coming decades. Improvements in the prevention, diagnosis and treatment of these deviceassociated infections will remain priority targets both for clinicians and the translational research community charged with addressing these challenges. Preclinical strategies, predictive of ultimate clinical efficacy, should serve as a control point for effective translation of new technologies to clinical applications. The development of new anti-infective medical devices requires a validated preclinical testing protocol; however, reliable validation of experimental and preclinical antimicrobial methodologies currently suffers from a variety of technical limitations. These include the lack of agreement or standardisation of experimental protocols, a general lack of correlation between in vitro and in vivo preclinical results and lack of validation between in vivo preclinical implant infection models and clinical (human) results. Device-associated infections pose additional challenges to practicing clinicians concerning diagnosis and treatment, both of which are complicated by the biofilms formed on the medical device. The critical challenges facing both preclinical research and clinical laboratories in improving both diagnosis and treatment of medical device-associated infections are the focus of this review. © 2014 AO Research Institute. All rights reserved. AD - AO Research Institute Davos, AO Foundation, Davos, Switzerland Departments of Pharmaceutics and Pharmaceutical Chemistry, Bioengineering University of Utah, Salt Lake City, UT 84112, United States AU - Moriarty, T. F. AU - Grainger, D. W. AU - Richards, R. G. DB - Scopus DO - 10.22203/eCM.v028a09 KW - Antibiotic resistance Clinical translational research In vitro-in vivo correlations Infection strategy Medical implants M3 - Article N1 - Cited By :29 Export Date: 10 November 2020 PY - 2014 SP - 112-128 ST - Challenges in linking preclinical anti-microbial research strategies with clinical outcomes for device-associated infections T2 - European Cells and Materials TI - Challenges in linking preclinical anti-microbial research strategies with clinical outcomes for device-associated infections UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84907816559&doi=10.22203%2feCM.v028a09&partnerID=40&md5=fa739679e3482bf42e3b612a4308f82d VL - 28 ID - 1301 ER - TY - JOUR AB - Background and Objective(s): Estimated life expectancy in persons with cerebral palsy (CP) is dependent on several factors, including the severity of gross motor functional limitations and the need for gastrostomy feeding. The objectives of our study were to describe mortality trends and disparities and identify preventable causes of death in persons with CP listed as the underlying cause of mortality. Study Design: Retrospective Cohort Study. Study Participants and Settings: The CDC WONDER Underlying Cause of Death database contains mortality and population counts for all U.S. counties. Data are based on death certificates for U.S. residents. Each death certificate contains a single underlying cause of death (UCOD), up to twenty additional contributing causes, and demographic data. This public health information is de-identified and collected into the CDC WONDER database which can be queried for public health statistical reporting and analysis. Materials and Methods: Using the CDC WONDER database for all US deaths, mortality trends with the UCOD of CP were examined based on age, gender and race for the years 1968-2016. To describe changes over time in the age at death in individuals with CP as the UCOD, the percentage of deaths in each age group (<10, 10-19, 20-34, 35-64, >65y) and rates (per 100 000) was compared over time, overall and stratified by race and gender. The CDC's Multiple Cause of Death database, available for the period 1999-2016, was used to describe the frequency of other contributing causes of death where CP was listed as an UCOD. Results: The predominant age at death in individuals with CP shifted over time from <10 years of age during the period 1968-1995 to the 35-64 year age group during the period 1996-2016. During the period 1999-2015, age-adjusted mortality with CP as an UCOD was higher for males (0.55) than females (0.42) and for black (0.65) relative to white (0.47) individuals. In analyses stratified by age group, the excess mortality with CP as an UCOD for black individuals was present only for the age range of birth through 54 years; for ages 55 years and older, CP-related mortality was higher for white relative to black individuals. Overall, the leading contributing causes of persons with CP as an UCOD, included several preventable causes; namely, pneumonia, pneumonitis due to food and vomit, and foreign body in the respiratory tract. Conclusions or Significance: The shift over time in the age at death with CP as an UCOD, from infancy and childhood to older ages, is consistent with improvements in the care and survival of infants and young children with CP. At the same time, racial disparities persist and many of the leading contributing causes of death in individuals with CP in recent years are preventable, pointing to the need for public health strategies to improve outcomes for individuals with CP. These findings point to potential strategies and public health interventions needed to further improve the life-expectancy and quality of life of all people with CP. AD - L. Lins, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States AU - Lins, L. AU - Remington, P. AU - Durkin, M. DB - Embase DO - 10.1111/dmcn.14353 KW - adult cause of death cerebral palsy child child death cohort analysis conference abstract controlled study death certificate demography female foreign body gender human infancy infant life expectancy male pneumonia public health quality of life race resident respiratory system retrospective study United States LA - English M3 - Conference Abstract N1 - L631671060 2020-05-11 PY - 2019 SN - 1469-8749 SP - 76 ST - Cerebral palsy-related mortality trends and disparities in the United States, 1968-2016 T2 - Developmental Medicine and Child Neurology TI - Cerebral palsy-related mortality trends and disparities in the United States, 1968-2016 UR - https://www.embase.com/search/results?subaction=viewrecord&id=L631671060&from=export http://dx.doi.org/10.1111/dmcn.14353 VL - 61 ID - 306 ER - TY - JOUR AB - PURPOSE: To assess the cellular reaction on the anterior surface of poly(methyl methacrylate) (PMMA) intraocular lenses (IOLs) implanted by phacoemulsification with continuous curvilinear capsulorhexis (CCC) or by extracapsular cataract extraction (ECCE) with a linear capsulotomy. SETTING: Cataract and Refractive Surgery Research Unit. Department of Ophthalmology, St. Thomas' Hospital, London, United Kingdom. METHODS: To document morphology, topography, and severity of the cellular reaction, specular microscopy of the anterior IOL surface was performed at 1 day, 1 week, and 1 and 3 months postoperatively in two parallel groups of 31 consecutive cataractous eyes operated on by phacoemulsification with CCC or by ECCE with a linear capsulotomy. RESULTS: The local tissue response consisted of a nonspecific foreign-body reaction to the IOL and a lens epithelial cell reaction. The foreign-body reaction was significantly less severe in the phacoemulsification group than in the ECCE group, and the number of IOLs without inflammatory cells was significantly higher. CONCLUSION: The foreign-body reaction to PMMA IOLs is significantly reduced when the lens is implanted by phacoemulsification with CCC. This could be of clinical benefit in high-risk eyes prone to the inflammatory complications of cataract surgery. AD - Eye Department, St. Thomas Hospital, United Kingdom AU - Pande, M. V. AU - Spalton, D. J. AU - Kerr-Muir, M. G. AU - Marshall, J. DB - Scopus DO - 10.1016/S0886-3350(96)80167-2 M3 - Article N1 - Cited By :26 Export Date: 10 November 2020 PY - 1996 SP - 811-817 ST - Cellular reaction on the anterior surface of poly(methyl methacrylate) intraocular lenses T2 - Journal of cataract and refractive surgery TI - Cellular reaction on the anterior surface of poly(methyl methacrylate) intraocular lenses UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030322917&doi=10.1016%2fS0886-3350%2896%2980167-2&partnerID=40&md5=7a3546cc23adaa6b6cf3a439fbb1b8a4 VL - 22 Suppl 1 ID - 1717 ER - TY - JOUR AB - Purpose: To assess the cellular reaction on the anterior surface of 4 types of foldable intraocular lenses (IOLs). Setting: Department of Ophthalmology, University Hospital of Vienna, Vienna, Austria. Methods: One hundred eyes scheduled for cataract surgery were prospectively randomized into 4 groups of 25 eyes each using random number tables. Group 1 received a Hydroview™ IOL (Bausch & Lomb), Group 2 an AcrySof® IOL (Alcon), Group 3 a MemoryLens® IOL (CRC), and Group 4 a CeeOn® 920 IOL (Pharmacia). Patients were examined 1, 3, 7, 30, 90, and 180 days postoperatively. Postoperative biomicroscopic examinations were done with a slitlamp, and a specular microscope was used to document the presence of cell deposits and identify areas with the highest density of cells. Results: The local tissue response revealed 2 patterns: a nonspecific foreign-body reaction to the IOL (small round, fibroblast-like, epithelioid, and giant cells) and a lens epithelial cell (LEC) reaction. The highest incidence of LECs was in the Hydroview group, in which LECs were present on 81.8% of lenses 180 days postoperatively. During the first postoperative days, small round and fibroblast-like cells were found on all IOLs. From 7 days on, the incidence and density of these cells were less severe in the Hydroview and CeeOn 920 groups. After several weeks, epithelioid cells and foreign-body giant cells were seen on some IOLs. These cells appeared more often on AcrySof, MemoryLens, and CeeOn IOLs. Conclusion: This study found ICL-related differences in cellular reaction after cataract surgery. The incidence of a nonspecific foreign-body reaction to 4 IOLs is consistent with the results of previous studies. The incidence of LECs was highest in the Hydroview group and lowest in the AcrySof group. The CeeOn 920 group had the lowest incidence of all types of cells. AD - Department of Ophthalmology, University Hospital of Vienna, Vienna, Austria Inst. of Tum. Biol. and Cancer Res., Dept. of Epidemiol., Univ. of Vienna, Vienna, Austria AU - Müllner-Eidenböck, A. AU - Amon, M. AU - Schauersberger, J. AU - Kruger, A. AU - Abela, C. AU - Petternel, V. AU - Zidek, T. DB - Scopus DO - 10.1016/S0886-3350(01)00846-X IS - 5 M3 - Article N1 - Cited By :54 Export Date: 10 November 2020 PY - 2001 SP - 734-740 ST - Cellular reaction on the anterior surface of 4 types of intraocular lenses T2 - Journal of Cataract and Refractive Surgery TI - Cellular reaction on the anterior surface of 4 types of intraocular lenses UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-17544396212&doi=10.1016%2fS0886-3350%2801%2900846-X&partnerID=40&md5=05249de004ed390b898f37714b39ed32 VL - 27 ID - 1670 ER - TY - JOUR AB - Objectives: The purpose of this study was to assess local inflammatory changes associated with the implantation of three different porcine collagen membranes having potential use in periodontal regeneration. Methods: Materials were implanted subcutaneously into prepared sites along the dorsal skin surface of 60 female Wistar rats. Saline and turpentine were used as negative and positive controls, respectively. Animals were killed and biopsies obtained after 3 d, and at 1, 2, 4, 6, and 8 weeks after membrane implantation. A panel of six monoclonal antibodies was used to identify circulating monocytes (ED1), resident tissue macrophages (ED2), lymphoid macrophages (ED3), Ia-antigen expression (OX6), T-lymphocytes (OX19), and B-lymphocytes (OX33). Cells identified by each antibody were subjected to quantitative immunocytochemistry to compare any differences present among groups. Sera obtained 8 weeks after grafting were used in immunoblotting assays to detect the presence of systemic antiporcine antibodies. Results: We found that the mononuclear cell subsets associated with implantation of porcine collagen membranes were similar to those obtained with saline administration. On the other hand, the use of turpentine resulted in an inflammatory infiltrate characterized by significantly higher numbers of all six monoclonal cell subsets at all time periods evaluated, compared to either saline or any of the membranes (P < 0.001). Conclusions: The collagen membranes do not appear to be associated with a significant local inflammatory response, nor a systemic immune response, and thus appear to be well tolerated, rendering them useful in periodontal regeneration. AD - Dept. of Periodont. and Endodontics, School of Dental Medicine, Buffalo, NY, United States Dept. of Oral Diagnostic Sciences, School of Dental Medicine, Buffalo, NY, United States Department of Microbiology, Sch. of Med. and Biomedical Sciences, State Univ. of New York at Buffalo, Buffalo, NY, United States School of Dental Medicine, SUNY at Buffalo, 250 Squire Hall, Buffalo, NY 14214, United States AU - Patino, M. G. AU - Neiders, M. E. AU - Andreana, S. AU - Noble, B. AU - Cohen, R. E. DB - Scopus DO - 10.1034/j.1600-0765.2003.00017.x IS - 5 KW - Barrier Collagen Inflammation Macrophages Membranes M3 - Article N1 - Cited By :25 Export Date: 10 November 2020 PY - 2003 SP - 458-464 ST - Cellular inflammatory response to porcine collagen membranes T2 - Journal of Periodontal Research TI - Cellular inflammatory response to porcine collagen membranes UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0344441915&doi=10.1034%2fj.1600-0765.2003.00017.x&partnerID=40&md5=a7929050a1b2cd968abd8ec3012bb1b0 VL - 38 ID - 1641 ER - TY - JOUR AB - Purpose: To develop a hydrophobic acrylic IOL with a hydrophilic, anti-cell adhesive surface characteristic. Setting: Department of Ophthalmology, Wakayama Medical University, Wakayama, Japan. Design: Experimental study. Methods: Hydrophobic acrylic IOLs were coated with hydrophilic 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer and implanted in rabbit eyes following lens extraction. Cell adhesion on the IOL surface was histologically compared with that on an uncoated IOL under light microscopy. Specimens were also observed under scanning electron microscopy to examine the effects of MPC coating on cell morphology. Results: Hydrophilic MPC coating reduced cell adhesion on acrylic IOLs at 1 month postoperatively. Conclusion: Coating an acrylic IOL with a hydrophilic polymer inhibited cell adhesion on the IOL surface. © 2011 ASCRS and ESCRS. AD - Department of Ophthalmology, Wakayama Medical University, 811-1 Kimiidera, Wakayama 641-0012, Japan AU - Ishikawa, N. AU - Miyamoto, T. AU - Okada, Y. AU - Saika, S. DB - Scopus DO - 10.1016/j.jcrs.2011.04.002 IS - 7 M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2011 SP - 1339-1342 ST - Cell adhesion on explanted intraocular lenses: Part 2: Experimental study of a surface-modified IOL in rabbits T2 - Journal of Cataract and Refractive Surgery TI - Cell adhesion on explanted intraocular lenses: Part 2: Experimental study of a surface-modified IOL in rabbits UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79959558285&doi=10.1016%2fj.jcrs.2011.04.002&partnerID=40&md5=80deb889c00aa8e764c2cb6ce2a90f73 VL - 37 ID - 1416 ER - TY - JOUR AB - Purpose: To determine whether cell adhesion on an intraocular lens (IOL) in Japanese patients is affected by the optic material. Setting: Department of Ophthalmology, Wakayama Medical University, Wakayama, Japan. Design: Experimental study. Methods: Intraocular lenses of various materials explanted from Japanese patients were histologically examined under light microscopy. Specimens included 271 poly(methyl methacrylate) (PMMA) IOLs, 117 hydrophobic soft acrylic IOLs, and 48 silicone IOLs. The mean cell adhesion on the central area of the anterior surface of each IOL material (referred to as cell number) was evaluated. Results: The cell number in the PMMA group was significantly higher than that in the silicone group in the periods of 1 to 5, 6 to 11, and more than 24 months. Although the cell number in the silicone group was less than one-third and one-twentieth the cell number in the hydrophobic soft acrylic group in the periods 1 to 5 months and 6 to 11 months, respectively, the difference was not statistically significant. Conclusion: In Japanese patients, the cell adhesion on silicone IOLs was less than that on PMMA IOLs. © 2011 ASCRS and ESCRS. AD - Department of Ophthalmology, Wakayama Medical University, 811-1 Kimiidera, Wakayama 641-0012, Japan AU - Ishikawa, N. AU - Miyamoto, T. AU - Okada, Y. AU - Saika, S. DB - Scopus DO - 10.1016/j.jcrs.2011.04.001 IS - 7 M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2011 SP - 1333-1338 ST - Cell adhesion on explanted intraocular lenses: Part 1: Analysis of explanted IOLs T2 - Journal of Cataract and Refractive Surgery TI - Cell adhesion on explanted intraocular lenses: Part 1: Analysis of explanted IOLs UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79959556536&doi=10.1016%2fj.jcrs.2011.04.001&partnerID=40&md5=b0d39eb33fb2e8ce4fa7360fe7e3d0b3 VL - 37 ID - 1414 ER - TY - JOUR AN - 106643987. Language: English. Entry Date: 20050610. Revision Date: 20150820. Publication Type: Journal Article AU - Davies, M. DB - ccm DP - EBSCOhost IS - 1 KW - Arthroplasty, Replacement, Hip Gauze Dressings Surgical Count Procedure N1 - letter. Journal Subset: Australia & New Zealand; Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. PY - 2005 SN - 1448-7535 SP - 9-9 ST - A cautionary tale...editor's response T2 - ACORN: The Journal of Perioperative Nursing in Australia TI - A cautionary tale...editor's response UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106643987&site=ehost-live&scope=site VL - 18 ID - 940 ER - TY - JOUR AB - Purpose: To introduce cases of the use, as patch grafts, of stromal lenticules obtained by small incision lenticule extraction (SMILE) surgery. Observations: Case 1 was a 79-year-old man who presented with Ahmed-valve-tube exposure in his left eye. His uncorrected visual acuity (UCVA) was 20/40, best-corrected visual acuity (BCVA) 20/32, and intraocular pressure (IOP) 11 mmHg. He was treated with stromal lenticule patch that had been extracted by SMILE surgery. The patch was positioned underneath of the conjunctiva and sutured to it. At postoperative 8 months, the graft site was well maintained without Ahmed valve-tube exposure, the UCVA was 20/32, BCVA 20/20, and IOP 12 mmHg. Case 2 was a 60-year-old man who presented with Ahmed-valve-tube exposure in his right eye. His UCVA was finger-count (FC) 30 cm, his BCVA 20/125, and his IOP 14 mmHg. He was treated with stromal lenticule patch by the same method as employed in case 1. At postoperative 10 days, tube re-exposure and displacement of the Ahmed valve external plate toward the limbus area occurred due to loosening of the anchoring suture. So, we removed the Ahmed valve device, which had been implanted in the supero-temporal area, and performed new Ahmed valve implantation, with a stromal lenticule flap instead of a partial scleral flap, in the supero-nasal area. As of 6 months post-reoperation, the patient was stable, with UCVA 20/200, BCVA 20/40 and IOP 13 mmHg. Case 3 was a 74-year-old man who presented with bullous keratopathy in his right eye, which was blind. Due to severe adhesions, his conjunctiva could not cover the entire cornea. Therefore, we performed a stromal lenticule patch graft with conjunctival advance flap. At postoperative 3 months, the patient's right eye was stable, without displacement or melting of the lenticule graft. Conclusions & importance: It is suggested that the stromal lenticule, with its biocompatibility, sufficient strength, ease of handling and low cost, is a useful patch graft for various therapeutic purposes in the ophthalmic field. AD - G.J. Yoon, Happy Eye21 Hospital, 950, Mujin-daero, Seo-gu, Gwangju, South Korea AU - Song, Y. J. AU - Kim, S. AU - Yoon, G. J. DB - Embase DO - 10.1016/j.ajoc.2018.09.009 KW - Ahmed valve contact lens suture adult aged article best corrected visual acuity blindness case report cataract extraction clinical article disease severity eye pain eye tissue foreign body glaucoma human intraocular pressure keratopathy male middle aged postoperative period pressure measurement reoperation retina detachment slit lamp microscopy small incision lenticule extraction tissue flap tissue graft vitrectomy LA - English M3 - Article N1 - L2001153528 2018-10-09 2018-10-11 PY - 2018 SN - 2451-9936 SP - 79-82 ST - Case series: Use of stromal lenticule as patch graft T2 - American Journal of Ophthalmology Case Reports TI - Case series: Use of stromal lenticule as patch graft UR - https://www.embase.com/search/results?subaction=viewrecord&id=L2001153528&from=export http://dx.doi.org/10.1016/j.ajoc.2018.09.009 VL - 12 ID - 329 ER - TY - JOUR AB - Necrotizing Fasciitis (NF) is a highly aggressive infectious process that affects soft tissues, with a high risk of rapid progression through superficial and deep levels of fascia, to the muscle layers. Some forms originate from odontogenous centres with the possibility of rapid evolution into forms of mediastinitis with high mortality rates. Systemic conditions that compromise the immune system of an organism can very easily induce the fatal development of these infectious processes. Prognosis is dependant upon the isolation of the germs that may be responsible in order to start a timely and specific therapeutic treatment; if the isolation is not supported by enough laboratory data to identify the range of action of the pathogens responsible, a wide ranging antibiotic treatment, and possibly surgical drains or treatment in a hyperbaric chamber, should be started. The clinical case that we shall describe is typical and rather complex. AD - University of Palermo, Department of Clinical Medicine and Emerging Diseases, Clinic of Internal Medicine, Italy University of Palermo, Faculty of Medicine and Surgery, GEN.UR.TO Department, Italy XI Mobile Section, Palermo, Italy University of Palermo, Faculty of Medicine and Surgery, Department of Orthopaedics and Traumatology, Italy AU - Pepe, I. AU - Agrusa, A. AU - Cusumano, G. AU - Rinella, M. R. AU - Fertitta, E. AU - Scozzari, F. AU - Adragna, F. AU - Gaglio, E. C. AU - Gulotta, P. AU - Foraci, A. C. AU - Martorana, U. AU - Gulotta, G. DB - Scopus IS - 3 KW - Complications Infections Necrotizing fasciitis M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2008 SP - 125-130 ST - Case report: Necrotizing fasciitis of odontogenic origin in a subject affected by uncompensated type 2 diabetes mellitus T2 - Acta Medica Mediterranea TI - Case report: Necrotizing fasciitis of odontogenic origin in a subject affected by uncompensated type 2 diabetes mellitus UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77953320108&partnerID=40&md5=6202600ba949033cdd64cb74a1e97d84 VL - 24 ID - 1543 ER - TY - JOUR AB - Context: Man-made vitreous fibers (MMVFs) are noncrystalline inorganic fibrous material used for thermal and acoustical insulation (e.g., rock wool, glass wool, glass microfibers, and refractory ceramic fibers). Neither epidemiologic studies of human exposure nor animal studies have shown a noticeable hazardous effect of glass wools on health. However, MMVFs have been anecdotally associated with granulomatous lung disease in several case reports. Case presentation: Here, we describe the case of a patient with multiple bilateral nodular opacities who was exposed to glass wool fibers and coating materials for 7 years. Bronchoalveolar lavage fluid revealed an increased total cell count (predominantly macrophages) with numerous cytoplasmic particles. Lung biopsy showed peribronchiolar infiltration of lymphoid cells and many foreign-body- type granulomas. Alveolar macrophages had numerous round and elongated platelike particles inside the cytoplasm. X-ray microanalysis of these particles detected mainly oxygen/aluminum/silicon and oxygen/magnesium/silicon, compatible with kaolinite and talc, respectively. No elemental evidence for glass fibers was found in lung biopsy. Discussion: The contribution of analytical electron microscopy applied in the lung biopsy was imperative to confirm the diagnosis of pneumoconiosis associated with a complex occupational exposure that included both MMVFs and coating materials. Relevance to clinical or professional practice: This case study points out the possible participation of other components (coating materials), beyond MMVFs, in the etiology of pneumoconiosis. AD - Departamento de Medicina Clínica, Hospital Universitário Antônio Pedro, Universidade Federal Fluminense, Niterói, Rio de Janeiro, Brasil AN - 105310400. Language: English. Entry Date: 20100409. Revision Date: 20200708. Publication Type: Journal Article AU - Ferreira, A. S. AU - Moreira, V. B. AU - Castro, M. C. S. AU - Soares, P. J. AU - Algranti, E. AU - Andrade, L. R. DB - ccm DO - 10.1289/ehp.0901110 DP - EBSCOhost IS - 2 KW - Granuloma -- Diagnosis Industry Lung Diseases -- Pathology Occupational Exposure Pneumoconiosis -- Diagnosis Adult Biopsy Male Microscopy, Electron N1 - case study; pictorial; tables/charts. Journal Subset: Blind Peer Reviewed; Editorial Board Reviewed; Peer Reviewed; Public Health; USA. NLM UID: 0330411. PMID: NLM20123612. PY - 2010 SN - 0091-6765 SP - 249-252 ST - Case report: analytical electron microscopy of lung granulomas associated with exposure to coating materials carried by glass wool fibers T2 - Environmental Health Perspectives TI - Case report: analytical electron microscopy of lung granulomas associated with exposure to coating materials carried by glass wool fibers UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105310400&site=ehost-live&scope=site VL - 118 ID - 749 ER - TY - JOUR AB - A 30years of old hypothyroid lady, presented with foul smelling excessive whitish per vaginal discharge, associated with itching in vulva & pain in the lower abdomen following caesarean section 3 months back. Her uterus was palpably enlarged and firm. USG revealed bulky uterus with wall echo shadow sign. A CT scan of whole abdomen was done that revealed intra-uterine textiloma. During laparotomy huge amount of pus came out through wound and a mob was found within uterine cavity. Textiloma is a rare problem of surgery arising from retained gauze during operation. Careful counting of surgical gauze before closure and identification by newer techniques is required to prevent this iatrogenic complication. AD - R. Begum, Department of Obstetrics and Gynecology, BIRDEM, Bangladesh AU - Begum, R. AU - Khanum, S. DB - Embase DO - 10.3329/bjog.v26i2.13791 IS - 2 KW - adult article benign uterus tumor body mass case report cesarean section colposcopy computer assisted tomography cytology endometrium female human human tissue hypothyroidism laparotomy obesity omentum patient assessment pelvis uterine cervicitis uterine cervix uterine cervix dysplasia uterus biopsy uterus textiloma vagina discharge vagina pain LA - English M3 - Article N1 - L365881939 2012-10-29 2012-10-31 PY - 2011 SN - 1018-4287 SP - 100-102 ST - Case report on textiloma of uterus T2 - Bangladesh Journal of Obstetrics and Gynecology TI - Case report on textiloma of uterus UR - https://www.embase.com/search/results?subaction=viewrecord&id=L365881939&from=export http://dx.doi.org/10.3329/bjog.v26i2.13791 VL - 26 ID - 549 ER - TY - JOUR AB - Rapunzel syndrome is very rare gastric foreign bodies that occur in children. It is a severe condition of a gastric trichobezoar with a long tail that passes into the small intestine. Here, we present the case of an 8-year-old girl with Rapunzel syndrome due to a very large (7 × 7 × 30cm) gastric trichobezoar. The patient had trichotillomania and trichophagia for 1 year prior to presentation. Ideally, small bezoars are removed through a minimally invasive method, such as endoscopic fragmentation. However, large trichobezoars, including those in Rapunzel syndrome, can only be managed with open surgical extraction, despite the large scars that may result. We report a case of Rapunzel syndrome with a large bezoar that was surgically removed after it was endoscopically cauterized with argon plasma. Endoscopic precutting was used to effectively reduce the size of the bezoar. © 2016 Wolters Kluwer Health, Inc. AD - Department of Pediatrics, Chonbuk National University Hospital, Jeonju, South Korea Department of Internal Medicine, Chonbuk National University Medical School and Hospital, Research Institute of Clinical Medicine, Jeonju, South Korea AU - Kim, S. C. AU - Kim, S. H. AU - Kim, S. J. C7 - e3745 DB - Scopus DO - 10.1097/MD.0000000000003745 IS - 22 M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2016 ST - A case report T2 - Medicine (United States) TI - A case report UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84975256391&doi=10.1097%2fMD.0000000000003745&partnerID=40&md5=f05568dd998f40ddf628631621e2896c VL - 95 ID - 1184 ER - TY - JOUR AB - Food bone perforation of the bowel is a relatively rare diagnosis. Its presentation is non-specific and often misdiagnosed. We present a case where a food bone perforation in both the large and small bowel was diagnosed on CT scan. A successful outcome was achieved with surgical treatment. © 2016 BMJ Publishing Group. All rights reserved. AD - Glasgow Royal Infirmary, Glasgow, United Kingdom Victoria Infirmary, Glasgow, United Kingdom AU - Coyte, A. AU - Aïssa, J. T. AU - Koh, H. C. AU - Mackay, G. C7 - 213767 DB - Scopus DO - 10.1136/bcr-2015-213767 M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2016 ST - Case of unrecognised food bone ingestion with dual site intestinal perforations T2 - BMJ Case Reports TI - Case of unrecognised food bone ingestion with dual site intestinal perforations UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84970003963&doi=10.1136%2fbcr-2015-213767&partnerID=40&md5=3c8539b3daba8a9c8ba9f64592d2c5dc VL - 2016 ID - 1180 ER - TY - JOUR AB - We report the case of a 52-year-old patient who was initially admitted to the District Hospital’s Surgery Ward with strong abdominal pain. The patient’s medical history before the hospitalization was unremarkable. The man did not recall any worrisome situations before the onset of pain. During the hospital stay, he underwent an ultrasound scan, computed tomography and magnetic resonance imaging evaluations, and laboratory tests suggesting that para-duodenal abscess or gastrointestinal stromal tumor should be considered. The patient was referred to the provincial hospital in order to undergo endoscopic ultrasonography. This was when a retroperitoneal foreign body, a toothpick, was found and removed. © Polish Ultrasound Society. AD - Gastroenterology Ward, L. Rydygier Provincial Hospital, Suwałki, Poland E. Rittler District Hospital, Sejny, Poland AU - Tynecki, W. AU - Tynecki, A. AU - Grobelna, A. AU - Baranowski, T. AU - Siemiaszko, G. AU - Łapiński, T. AU - Wilczek, J. DB - Scopus DO - 10.15557/JoU.2020.0024 IS - 81 KW - Foreign body ingestion Gastric perforation Toothpick M3 - Article N1 - Export Date: 10 November 2020 PY - 2020 SP - e151-e153 ST - A case of ultrasound diagnosis of retroperitoneal lesion caused by unnoticed foreign body ingestion T2 - Journal of Ultrasonography TI - A case of ultrasound diagnosis of retroperitoneal lesion caused by unnoticed foreign body ingestion UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85086675990&doi=10.15557%2fJoU.2020.0024&partnerID=40&md5=ca697c3dc9edfcb0fec1500e9cbc8ef8 VL - 20 ID - 964 ER - TY - JOUR AB - Introduction The gossypibomas is an inflammatory granuloma centered by textile fibers forgotten during surgery. Renal gossypibomas is a rare post-operative complication. The authors report a case of gossypibomas simulating kidney tumor pathological discovery. Observation The patient A. G. 53 years old, with a history of left nephrolithotomy by lumbotomy 5 years earlier was admitted for left lumbar pain lasting for 4 months. The uro-scan was consistent with an upper polar cyst Bosniack III. Macroscopic examination of the nephrectomy piece noted, a cystic cavity 7x6 cm containing gauze surrounded by a gelatinous substance. The histological sections showed a thickened wall, including calcification foci and granulomatous reaction to foreign bodies. The diagnosis of a pseudo-tumor gossypibomas left kidney was retained. Conclusion The textile fibers may trigger an acute inflammatory reaction with formation of a perirenal abcess if aseptic resulting in the formation of fibrotic foci, encystment and calcification. Renal gossypibomas pose diagnostic difficulties in the absence of pathognomonic clinical and radiological signs. The presence of a renal mass associated with a history of kidney surgery on the same side should suggest first a gossypibomas. The treatment is surgical. Partial nephrectomy is the treatment of choice. The best treatment remains prevention by careful gauze counts, and surgical drapes in the beginning and end of intervention. AD - K. Doh, Pathologiste, Hôpital Aristide Le Dantec, Pavillon BICHAT, Avenue Pasteur, BP : 3001 DAKAR, Senegal AU - Doh, K. AU - Thiam, I. AU - Takin, R. C. A. AU - Bissirou, I. AU - Gaye, G. W. DB - Embase DO - 10.1016/j.afju.2016.12.002 IS - 4 KW - adult article calcification case report clinical article computer assisted tomography cyst disease duration foreign body granulomatosis histopathology hospital admission human human tissue kidney disease kidney tumor low back pain lumbotomy medical history middle aged nephrolithotomy postoperative complication pseudotumor pseudotumor gossypibomas left kidney surgical technique LA - English French M3 - Article N1 - L614328691 2017-02-10 2018-01-19 PY - 2017 SN - 1110-5704 SP - 364-367 ST - A case of renal gossypibomas mimicking tumor pathological discovery T2 - African Journal of Urology TI - A case of renal gossypibomas mimicking tumor pathological discovery UR - https://www.embase.com/search/results?subaction=viewrecord&id=L614328691&from=export http://dx.doi.org/10.1016/j.afju.2016.12.002 VL - 23 ID - 359 ER - TY - JOUR AB - Three days after extraction of a foreign body from the centre of the right cornea a 15-year-old boy showed an acute ring abscess with a greenish hypopyon. The strain was sensitive to streptomycin (1:500). Treatment was (after a short trial of penicillin) with intramuscular streptomycin (three-hourly) instillation, subconjunctival injection and introduction into anterior chamber (1.0 Gm streptomycin in all). Corneal Saemisch's section was performed. Healing resulted. After iridectomy ab externo finger counting was possible. AU - Maschler, J. DB - Embase Classic IS - 7 KW - penicillin G streptomycin abscess anterior eye chamber boy cornea extraction foreign body healing hypopyon iridectomy subconjunctival drug administration LA - English M3 - Article N1 - L280453246 1948-12-01 PY - 1948 SN - 0007-1161 SP - 426-428 ST - A case of pyocyaneus ring abscess of the cornea treated with streptomycin T2 - British Journal of Ophthalmology TI - A case of pyocyaneus ring abscess of the cornea treated with streptomycin UR - https://www.embase.com/search/results?subaction=viewrecord&id=L280453246&from=export VL - 32 ID - 696 ER - TY - JOUR AB - Introduction and Background: Implantable ventricular assist devices (VADs) might be a key tool to counter organ scarcity. Despite technological improvements VADs are still related to complications e.g. bleeding, driveline infection, thrombosis or stroke causing an increasing number of patients receiving HTX from device. Due to numerous tissue adhesions HTX is getting technically more challenging. The time-consuming approach often leads to an incomplete removal of driveline and outflow graft material. Methods: We report about a 49 years old male pat. with ischemic cardiomyopathy who received a VAD in 2013 and HTX in 2014. 1 year later the pat. was admitted to hospital with left sided chest pain. Apart from swelling local findings didn't reveal further signs of inflammation. Inflammatory markers were slightly increased, blood culture sets remained negative. Thoracic CT revealed signs of osteomyelitis in the ventral parts of the left 4th rib. After operative removal osteoid material was sent for microbiol. testing which revealed colonization with Candida and Staph. epidermidis. An anti-infective therapy was initiated. Due to persistent pain despite opioids we reevaluated the thoracic images and a 15 cm long piece of remaining driveline located in the 4th to 5th intercostal space was identified. Indication for driveline removal was set. Afterward a sudden pain relief and decrease of WBC count and CRP was seen and the pat. was discharged. Results and Conclusions: In long-term VAD support driveline infections are still a key problem. Whether this also affects remaining driveline after HTX is still not known. Due to obligatory immunosuppression after HTX the general risk for infection is increased and the complete VAD excision including the removal of all foreign material seems to be the most appropriate approach. In the described case remaining driveline caused persistent pain and several readmissions to hospital accompanied by social isolation, reduced quality of life, disability to work and a great financial burden for public health system. AD - E. Harmel, University Heart Center Hamburg, Cardiac Surgery, Hamburg, Germany AU - Harmel, E. AU - Barten, M. J. AU - Philipp, S. AU - Rybczynski, M. AU - Reichenspurner, H. AU - Sill, B. DB - Embase DO - 10.1111/tri.12829 KW - adult adverse device effect analgesia anti-infective therapy blood culture Candida case report disability driveline infection excision foreign body heart transplantation hospital readmission human immunosuppressive treatment ischemic cardiomyopathy leukocyte count male middle aged nonhuman osteoid osteomyelitis public health quality of life rib social isolation swelling thorax pain LA - English M3 - Conference Abstract N1 - L617989755 2017-08-30 PY - 2016 SN - 1432-2277 SP - 34 ST - A case of osteomyelitis in patient with remaining assist device driveline after heart transplantation-a case report T2 - Transplant International TI - A case of osteomyelitis in patient with remaining assist device driveline after heart transplantation-a case report UR - https://www.embase.com/search/results?subaction=viewrecord&id=L617989755&from=export http://dx.doi.org/10.1111/tri.12829 VL - 29 ID - 396 ER - TY - JOUR AD - Department of General Surgery, Singapore General Hospital, Singapore Gleneagles Hospital, Singapore Department of General Surgery, Singapore General Hospital, Outram Road, 169608 Singapore, Singapore AU - Goh, B. K. P. AU - Jeyaraj, P. R. AU - Chan, H. S. AU - Ong, H. S. AU - Agasthian, T. AU - Chang, K. T. E. AU - Wong, W. K. DB - Scopus DO - 10.1007/s10620-004-9595-y IS - 11-12 KW - Fish bone Pancreas Pancreatic carcinoma Pancreatic mass Perforation M3 - Article N1 - Cited By :34 Export Date: 10 November 2020 PY - 2004 SP - 1935-1937 ST - A case of fish bone perforation of the stomach mimicking a locally advanced pancreatic carcinoma T2 - Digestive Diseases and Sciences TI - A case of fish bone perforation of the stomach mimicking a locally advanced pancreatic carcinoma UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-13644251565&doi=10.1007%2fs10620-004-9595-y&partnerID=40&md5=16d7c85751270370690b5a8e3f244313 VL - 49 ID - 1620 ER - TY - JOUR AB - Visceral injuries are not uncommon in nonaccidental trauma and often require emergent operative intervention. However, sometimes it can be difficult to assess the extent of injury. In this report, we present a case of child physical abuse resulting in bladder and rectal perforations, which was initially referred to our hospital as acute abdomen with intraperitoneal free fluid on ultrasonography. An exploratory laparotomy revealed the perforations and surgical repair was performed. The patient was evaluated by the Hospital Child Protective team and it was revealed that bladder and rectum perforations were due to insertion of rolling pin into the rectum by the stepmother. The child was discharged home uneventfully with a temporary colostomy. We believe that this is the first reported case in the English literature of inflicted perforation of the rectum and bladder through insertion of a rolling pin. © 2018 Wolters Kluwer Health, Inc. All rights reserved. AD - Departments of Pediatrics, Social Pediatrics Unit, Erciyes University Faculty of Medicine, Kayseri, 38039, Turkey Pediatric Radiology, United States Pediatric Surgery, Turkey Forensic Medicine, Turkey Child Psychiatry, Erciyes University Faculty of Medicine, Kayseri, Turkey AU - Kondolot, M. AU - Doganay, S. AU - Turan, C. AU - Asil, H. AU - Oztop, D. B. AU - Ozdemir, C. DB - Scopus DO - 10.1097/PEC.0000000000000883 IS - 3 KW - acute abdomen bladder perforation child abuse rectal injury rolling pin M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 SP - e44-e46 ST - A Case of Child Physical Abuse with a Rolling Pin Insertion, Resulting in Bladder and Rectal Perforation T2 - Pediatric Emergency Care TI - A Case of Child Physical Abuse with a Rolling Pin Insertion, Resulting in Bladder and Rectal Perforation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84991479861&doi=10.1097%2fPEC.0000000000000883&partnerID=40&md5=585d7f85531d22fccb5bc8b9ddc9ef21 VL - 34 ID - 1087 ER - TY - JOUR AB - CONTEXT: We describe a case of acute retinal toxicity caused by an intraocular foreign body composed of a cobalt alloy. CASE PRESENTATION: A 36-year-old man presented to an outside clinic with a traumatic cataract and corneal laceration of his left eye, which had occurred while grinding a shelf. The lacerated cornea was closed primarily and the traumatic cataract was phacoemulsified. He was transferred to our hospital due to identification of a metallic intraocular foreign body in the vitreous. On arrival at our institution, the intraocular foreign body was removed as soon as possible after vitrectomy. On the first postoperative day, vasculitis and serous retinal detachment were observed on the retina at the previous site of the foreign body. Two months after surgery, atrophy of nearly half of the inferior retina was noted on funduscopy, and visual acuity was such that the patient could only count fingers at 30 cm. Analysis of the foreign body revealed that it was composed of 84.99% tungsten carbide, 15% cobalt and had traces of titanium and alumina. DISCUSSION: Cobalt containing metallic foreign bodies should be immediately removed, as they have the potential to cause permanent visual disturbance. AD - Department of Ophthalmology, College of Medicine, Kosin University , Busan , South Korea . AN - 23826809 AU - Kang, J. Y. AU - Lee, S. U. AU - Nam, K. Y. AU - Kim, T. W. AU - Lee, S. J. DA - Jun DO - 10.3109/15569527.2013.808655 DP - NLM ET - 2013/07/06 IS - 2 KW - Adult Alloys/*toxicity Atrophy/chemically induced/pathology Cobalt/*toxicity *Eye Foreign Bodies Humans Male Retina/pathology Retinal Diseases/*chemically induced/pathology Cobalt penetrating injury retina trauma LA - eng N1 - 1556-9535 Kang, Jung Youb Lee, Seung Uk Nam, Ki Yup Kim, Tae Won Lee, Sang Joon Case Reports Journal Article England Cutan Ocul Toxicol. 2014 Jun;33(2):91-3. doi: 10.3109/15569527.2013.808655. Epub 2013 Jul 5. PY - 2014 SN - 1556-9527 SP - 91-3 ST - A case of acute retinal toxicity caused by an intraocular foreign body composed of cobalt alloy T2 - Cutan Ocul Toxicol TI - A case of acute retinal toxicity caused by an intraocular foreign body composed of cobalt alloy VL - 33 ID - 139 ER - TY - JOUR AB - Pleural effusions are commonly drained with Seldinger intercostal drains. One uncommon but serious risk of drain insertion is that of a foreign body being retained in the pleural cavity following removal. We report a case in which the tip of the drain was retained in the pleural space following difficult insertion of a Seldinger intercostal drain in a district general hospital. Prompt recognition and clear patient communication are important at the occurrence of an unusual complication. Surgical removal of the foreign body was performed following transfer. We report this case to raise awareness that insertion and withdrawal of drains over the guidewire during insertion may damage the drain and highlight the need for doctors who insert chest drains to perform a count of instruments during ward or clinic-based procedures as well as those performed in theatres. We now include removable parts of chest drains in our theatre instrument count. AD - Department of Thoracic Surgery, Heart of England NHS Foundation Trust, Bordesley Green East, Birmingham, UK nicola.oswald@doctors.org.uk. Department of Thoracic Surgery, Heart of England NHS Foundation Trust, Bordesley Green East, Birmingham, UK. AN - 27076623 AU - Oswald, N. K. AU - Abdelaziz, M. AU - Rajesh, P. B. AU - Steyn, R. S. C2 - PMC4830459 DA - Apr 13 DO - 10.1093/jscr/rjw055 DP - NLM ET - 2016/04/15 IS - 4 LA - eng N1 - 2042-8812 Oswald, Nicola K Abdelaziz, Mahmoud Rajesh, Pala B Steyn, Richard S Case Reports J Surg Case Rep. 2016 Apr 13;2016(4):rjw055. doi: 10.1093/jscr/rjw055. PY - 2016 SN - 2042-8812 (Print) 2042-8812 ST - A case of a retained drain tip following intercostal drain insertion: avoiding a 'never event' T2 - J Surg Case Rep TI - A case of a retained drain tip following intercostal drain insertion: avoiding a 'never event' VL - 2016 ID - 175 ER - TY - JOUR AD - Department of Neuroradiology, Massachusetts General Hospital, Harvard Medical School, Boston, United States Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, United States Department of Ophthalmology, Massachusetts Eye and Ear Institute, Harvard Medical School, Boston, United States Department of Radiology, Harvard Medical School, Boston, United States Department of Ophthalmology, Harvard Medical School, Boston, United States AU - Gupta, R. AU - Vavvas, D. AU - Asaad, W. F. DB - Scopus DO - 10.1056/NEJMcpc1310007 IS - 20 M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2015 SP - 1945-1952 ST - Case 15-2015: A 27-year-old man with a nail in the eye T2 - New England Journal of Medicine TI - Case 15-2015: A 27-year-old man with a nail in the eye UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84929378825&doi=10.1056%2fNEJMcpc1310007&partnerID=40&md5=ff4d760059dde00cb6443f65a8f65216 VL - 372 ID - 1228 ER - TY - JOUR AB - We describe a case of carotid-esophageal fistula due to retention of an ingested foreign body in a 65-year-old woman. Late diagnosis resulted in severe hemorrhage and postoperative cerebrovascular accident because of the impossibility of repairing the carotid artery due to severe local inflammation. © The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav. AD - Imam Reza Hospital, Tabriz University of Medical Sciences, Golgasht St., Tabriz, Iran AU - Behesthirouy, S. AU - Kakaei, F. DB - Scopus DO - 10.1177/0218492313502210 IS - 8 KW - Carotid artery injuries Esophageal fistula Foreign bodies Hematemesis Hemorrhage Stroke M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2014 SP - 984-986 ST - Carotid-esophageal fistula due to a retained foreign body T2 - Asian Cardiovascular and Thoracic Annals TI - Carotid-esophageal fistula due to a retained foreign body UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84910067508&doi=10.1177%2f0218492313502210&partnerID=40&md5=da0e28d9a02e9d31e69947c70026b2b5 VL - 22 ID - 1267 ER - TY - JOUR AB - Rice body formation in a joint or bursa is a rare condition, and is usually associated with rheumatoid arthritis or tuberculous arthritis. Here we describe a case of multiple rice body formation in a shoulder joint and in adjacent bursae, which was confirmed to be due to septic arthritis by Candida species. To the best of our knowledge, rice body formation in Candida septic arthritis in an immune-competent patient has not been previously reported. AD - Departments of Radiology, Gachon University, Gil Hospital, Incheon 405-760, South Korea Departments of Pathology, Gachon University, Gil Hospital, Incheon 405-760, South Korea Departments of Orthopedic Surgery, Gachon University, Gil Hospital, Incheon 405-760, South Korea AU - Jeong, Y. M. AU - Cho, H. Y. AU - Lee, S. W. AU - Hwang, Y. M. AU - Kim, Y. K. DB - Scopus DO - 10.3348/kjr.2013.14.3.465 IS - 3 KW - Arthritis Candida MRI Rice bodies M3 - Article N1 - Cited By :12 Export Date: 10 November 2020 PY - 2013 SP - 465-469 ST - Candida septic arthritis with rice body formation: A case report and review of literature T2 - Korean Journal of Radiology TI - Candida septic arthritis with rice body formation: A case report and review of literature UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84877966587&doi=10.3348%2fkjr.2013.14.3.465&partnerID=40&md5=e849de5ab43165d55790e6374b387fb9 VL - 14 ID - 1321 ER - TY - JOUR AN - 105164647. Language: English. Entry Date: 20100507. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 10 KW - Chronic Pain Courts -- Legislation and Jurisprudence -- Texas Malpractice -- Legislation and Jurisprudence -- Texas Surgical Sponges -- Adverse Effects Time Factors Abdominal Pain Health Status Surgical Count Procedure Texas N1 - legal case. Journal Subset: Blind Peer Reviewed; Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Legal Case: Walters v. Cleveland Regional Medical Center [2010 TX]. NLM UID: 100936959. PMID: NLM20499619. PY - 2010 SN - 1528-848X SP - 2-2 ST - Can suit succeed after expiration of limitations? T2 - Nursing Law's Regan Report TI - Can suit succeed after expiration of limitations? UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105164647&site=ehost-live&scope=site VL - 50 ID - 935 ER - TY - JOUR AN - 107512415. Language: English. Entry Date: 19900201. Revision Date: 20150712. Publication Type: Journal Article. Journal Subset: Core Nursing DB - ccm DP - EBSCOhost IS - 6 KW - Malpractice -- Legislation and Jurisprudence -- Alabama Liability, Legal -- Alabama Medical-Surgical Nursing -- Legislation and Jurisprudence -- Alabama Alabama Jurisprudence -- Alabama Surgery, Obstetrical -- Adverse Effects Surgical Sponges -- Adverse Effects Inpatients Female N1 - Nursing; Peer Reviewed; USA. NLM UID: 0352140. PY - 1989 SN - 0034-3196 SP - 2-2 ST - Can doctor rely on your sponge count? T2 - Regan Report on Nursing Law TI - Can doctor rely on your sponge count? UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107512415&site=ehost-live&scope=site VL - 30 ID - 947 ER - TY - JOUR AD - Cornea, Cataract and Refractive Surgery, Dr. Shroff's Charity Eye Hospital, 5027, Kedarnath Marg, New Delhi, Daryaganj 110002, India AU - Farooqui, J. H. AU - Kapur, N. AU - Jha, U. P. AU - Patel, N. V. AU - Mathur, U. DB - Scopus DO - 10.1016/j.jfo.2019.06.020 IS - 1 M3 - Article N1 - Export Date: 10 November 2020 PY - 2020 SP - 97-100 ST - Un lenticul de DSAEK détaché peut-il encore fonctionner ? T2 - Journal Francais d'Ophtalmologie TI - Can a detached DSAEK donor lenticule still work? UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076490761&doi=10.1016%2fj.jfo.2019.06.020&partnerID=40&md5=846fed490df7238cbd17985c83a4a725 VL - 43 ID - 979 ER - TY - JOUR AB - Meckel's diverticulum is the most common congenital anomaly of the gastrointestinal tract. It is relatively uncommon, however, for patients to become symptomatic and rarer still for foreign bodies to become lodged within a Meckel's diverticulum. Here we present one such case in which a button battery was lodged in a Meckel's diverticulum, along with the patient's subsequent interdisciplinary management and review of the relevant literature. © 2018 AD - Division of Pediatric Surgery, Department of Surgery, Albert Einstein College of Medicine/The Children's Hospital at Montefiore, United States Department of Pediatrics, Albert Einstein College of Medicine/The Children's Hospital at Montefiore, United States Division of Pediatric Gastroenterology, Hepatology, and Nutrition, The Children's Hospital at Montefiore, United States AU - Farber, B. A. AU - Shaul, E. AU - LaQuaglia, M. J. AU - Janofsky, E. AU - Statter, M. B. AU - Jan, D. M. AU - Borenstein, S. H. AU - Rudolph, B. DB - Scopus DO - 10.1016/j.epsc.2018.04.003 KW - Button battery Foreign body ingestion Meckel's diverticulum M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 SP - 52-54 ST - Button battery lodged in Meckel's diverticulum T2 - Journal of Pediatric Surgery Case Reports TI - Button battery lodged in Meckel's diverticulum UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85044950176&doi=10.1016%2fj.epsc.2018.04.003&partnerID=40&md5=16cd580c6f7c55246ad2afa5bbd020ce VL - 33 ID - 1075 ER - TY - JOUR AB - Buried bumper syndrome (BBS) is a relatively rare complication of percutaneous endoscopic gastrostomy (PEG) feeding. In this paper, we report the case of a 74-year-old man who attended the emergency department with bleeding from the PEG tube site that was later confirmed by endoscopy to be BBS. The treatment consisted of a PEG tube replacement with a 10-day course of antibiotics. Furthermore, this report discusses possible signs, symptoms and physical examination signs suggesting BBS. It can cause serious complications that might sometimes be fatal. Therefore, the diagnosis needs to be done swiftly and the patient treatment to start without delay. BBS should always top the differentials of physicians once suspected. © 2018 BMJ Publishing Group Limited. AD - Gastroenterology Department, Dubai Health Authority, Dubai, United Arab Emirates Internal Medicine, Dubai Health Authority, Dubai, United Arab Emirates AU - Bamakhrama, K. AU - Aldaham, T. A. AU - Alassaf, O. C7 - e225876 DB - Scopus DO - 10.1136/bcr-2018-225876 IS - 1 KW - endoscopy gastrointestinal system parenteral/enteral feeding M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2018 ST - Buried bumper syndrome presenting with bleeding T2 - BMJ Case Reports TI - Buried bumper syndrome presenting with bleeding UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85058555800&doi=10.1136%2fbcr-2018-225876&partnerID=40&md5=c1fe496575deab66b408496f6c17855b VL - 11 ID - 1051 ER - TY - JOUR AB - Introduction & Objective: The foreign bodies within the ureter are extremely rare and they include iatrogenic bodies as fragmented ureteral stents, angio-embolization coils, traumatic sharpnel or bullet and foreign bodies introduced per urethra. In this case, a patient with buckshot centered nucleous-matrix ureterolithiasis due to gunshot injury was presented. Methods: Case Presentation: Fifty-five year old man who referred for left flank pain for 3 months. The patient underwent laparotomy caused by gunshot injury to abdominal area 6 months ago. During this time there was no history of hematuria, febrile urinary tract infection and abdominal pain. The physical examination was unremarkable. Complete blood count was normal and urine culture was negative. Creatinin rate was 1.1 mg/dl. Left side hydroureteronephrosis, upper third ureteric calculi and ureteric foreign body seen on abdominal computed tomography. Results: We decided to perform left ureteroscopy to the patient. A holmium laser lithotripter was used to break the stone during ureteroscopy. It was observed that the bullet inside the stone matrix was the core. After the stone was completely shredded, we removed the buckshot core with endoscopic forceps. Conclusions: Ureteral trauma is uncommon, accounting for less than %1 of all urologic traumas. Penetrating ureteral injuries are more common than blunt uretral injuries in adults Upper third of the ureter is more often injured than the midlle and lower thirds. Complications of ureteric injury are; infected urinomas, ureteric fistulas, ureteric stenosis, and retroperitoneal abscesses. The reason we have presented this case is there is no complication of urinary system due to intra ureteric foreign body within 6 months. AD - M. Sönmez, Necmettin Erbakan University, Meram Medical Faculty, Department of Urology, Turkey AU - Sönmez, M. AU - Kilinç, M. AU - Atici, A. AU - Ö ztürk, A. AU - Göger, Y. E. DB - Embase DO - 10.1089/end.2018.29043.abstracts KW - creatinine abdominal pain adult blood cell count case report clinical article complication computer assisted tomography conference abstract fistula flank forceps foreign body gunshot injury hematuria holmium laser human hydroureter laparotomy lithotripter male middle aged physical examination retroperitoneal abscess stenosis ureter injury ureter stone ureteroscopy urinary tract infection urine culture urinoma LA - English M3 - Conference Abstract N1 - L626876116 2019-03-27 PY - 2018 SN - 1557-900X SP - A497-A498 ST - Buckshot centered nucleous-matrix ureterolithiasis due to gunshot injury T2 - Journal of Endourology TI - Buckshot centered nucleous-matrix ureterolithiasis due to gunshot injury UR - https://www.embase.com/search/results?subaction=viewrecord&id=L626876116&from=export http://dx.doi.org/10.1089/end.2018.29043.abstracts VL - 32 ID - 336 ER - TY - JOUR AB - Bronchiolitis obliterans (BO) was defined as a nonreversible obstructive lung disease in which the bronchioles are always compressed and narrowed by fibrosis or inflammation. In the severe event of lung collapse after BO, surgical intervention is often recommended, and conservative therapy is thought to be ineffective. Here, we report the case of a 9-year old girl clinically diagnosed as having bronchiolitis obliterans with abrupt occlusion of the right B4b bronchus. After a lamotrigine-induced Stevens-Johnson syndrome (SJS) occurred, she presented with total collapse of the right lung on admission, which was subsequently complicated by a pneumothorax during conservative treatment, but with the re-expansion of the right upper lobe after intervention. The case indicates the possibility of reversing pulmonary atelectasis in BO. Thus, surgery may not be necessary. © 2012. AD - Department of Thoracic Surgery, Tangdou Hospital, The Fourth Military Medical University, Xi'an, Shannxi, China Department of Imaging, Tangdou Hospital, The Fourth Military Medical University, Xi'an, Shannxi, China AU - Wang, W. P. AU - Ni, Y. F. AU - Wei, Y. N. AU - Li, X. F. AU - Cheng, Q. S. AU - Lu, Q. DB - Scopus DO - 10.1016/j.jfma.2012.02.026 IS - 3 KW - Bronchiolitis obliterans Lamotrigine Stevens-Johnson syndrome M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2015 SP - 285-289 ST - Bronchiolitis obliterans complicating a pneumothorax after Stevens-Johnson syndrome induced by lamotrigine T2 - Journal of the Formosan Medical Association TI - Bronchiolitis obliterans complicating a pneumothorax after Stevens-Johnson syndrome induced by lamotrigine UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84930384257&doi=10.1016%2fj.jfma.2012.02.026&partnerID=40&md5=38e3bf6c19a57ad82432f35b2c9589fc VL - 114 ID - 1248 ER - TY - JOUR AB - Background: Bronchiectasis, with was once thought to be an orphan disease, is now being recognized with increasing frequency around the world. Patients with bronchiectasis have chronic cough and sputum production, and bacterial infections develop in that result in the loss of lung function. Bronchiectasis occurs in patients across the spectrum of age and gender, but the highest prevalence is in older women. The diagnosis of bronchiectasis is made by high-resolution CT scans. Bronchiectasis, which can be focal or diffuse, may occur without antecedent disease but is often a complication of previous lung infection or injury or is due to underlying systemic illnesses. Patients with bronchiectasis may have predisposing congenital disease, immune disorders, or inflammatory disease. The treatment of bronchiectasis is multimodality, and includes therapy with antibiotics, anti-inflammatory agents, and airway clearance. Resectional surgery and lung transplantation are rarely required. The prognosis for patients with bronchiectasis is variable given the heterogeneous nature of the disease. A tailored, patient-focused approach is needed to optimally evaluate and treat in individuals with bronchiectasis. Bronchiectasis is destruction and widening of the large airways. If the condition is present at birth, it is called congenital bronchiectasis. Causes: Bronchiectasis is often caused by recurrent inflammation or infection of the airways. Sometimes it begins in childhood after a more severe lung infection or inhaling a foreign object. Cystic fibrosis causes about a third of all bronchiectasis cases in the United States. Certain genetic conditions can also cause bronchiectasis, including primary ciliary dyskinesia and immunodeficiency syndromes. The condition can also be caused by routinely breathing in food particles while eating. Symptoms: Symptoms often develop gradually, and may occur months or years after the event that causes the bronchiectasis. The may include: (I) bluish skin color; (II) breath odor; (III) chronic cough with large amounts of foul-smelling sputum; (IV) clubbing of fingers; (V) coughing up blood; (VI) fatigue; (VII) paleness; (VIII) shortness of breath that gets worse with exercise; (IX) weigh loss and (X) wheezing. Exams and tests: When listening to the chest with a stethoscope, the doctor may hear small clicking, bubbling, wheezing, rattling, or other sounds, usually in the lower lobes of the lungs. Test may include: (I) aspergillosis precipitin test; (II) aipha-1; (III) antitrypsin blood test; (IV) chest X-ray; (V) chest CT; (VI) sputum culture; (VII) complete blood count; (VIII) genetic testing, including sweat test for cystic fibrosis; (IX) PPD skin test to check for a prior tuberculosis infection and (X) serum immunoglobulin electrophoresis. Treatment: Treatment is aimed at controlling infections and bronchial secretions, relieving airway obstruction, and preventing complications. Regular, daily drainage to remove bronchial secretions is a routing part of treatment. A respiratory therapist can show the patient coughing exercises that will help. Antibiotics, bronchodilators, and expectorants are often prescribed for infections, Surgery to resect the lung may be needed if medicine does not work or if the patient has, massive bleeding. Prognosis: The outlook depends on the specific causes of the disease. With treatment, most people can lead normal lives without major disability. Possible complications: (I) coughing up blood; (II) low oxygen levels; (III) recurrent pneumonia. Prevention: The risk may be reduced if lung infections are promptly treated. Childhood vaccinations and a yearly flu vaccine help reduce the change of some infections. Avoiding upper respiratory infections, smoking, and pollution may also reduce your risk or infection. AD - I. Organtzis, University Pulmonary Department, G.Papanikolaou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece AU - Organtzis, I. AU - Papakosta, D. AU - Foyka, E. AU - Lampaki, S. AU - Lagoudi, K. AU - Moumtzi, D. AU - Kostanta, S. AU - Sourla, E. AU - Papadaki, E. DB - Embase DO - 10.3978/j.issn.20721439.2015.AB035 KW - alpha 1 antitrypsin antiinflammatory agent bronchodilating agent endogenous compound expectorant agent influenza vaccine macrolide oxygen airway obstruction aspergillosis bleeding blood cell count bronchus secretion child childhood chronic cough clinical study complication cystic fibrosis destruction diagnosis digital clubbing disability drug therapy dyspnea eating electrophoresis fatigue female food gender genetic screening hemoptysis high resolution computer tomography human human tissue immune deficiency immunoglobulin blood level injury Kartagener syndrome lung clearance lung infection lung transplantation male medicine odor pallor pneumonia prevalence prognosis rare disease respiratory therapist serodiagnosis skin color skin test smoking sound spirometry sputum culture stethoscope surgery sweat test symptom thinking thorax radiography tuberculosis United States upper respiratory tract infection vaccination wheezing LA - English M3 - Conference Abstract N1 - L615258114 2017-04-13 PY - 2015 SN - 2077-6624 ST - Bronchiectasis diagnosis and treatment T2 - Journal of Thoracic Disease TI - Bronchiectasis diagnosis and treatment UR - https://www.embase.com/search/results?subaction=viewrecord&id=L615258114&from=export http://dx.doi.org/10.3978/j.issn.20721439.2015.AB035 VL - 7 ID - 437 ER - TY - JOUR AB - Purpose To evaluate the efficacy and ocular safety of bromfenac ophthalmic solution 0.07% (Prolensa) dosed once daily for the treatment of ocular inflammation and pain in subjects who underwent cataract surgery with posterior chamber intraocular lens implantation. Design Two phase 3, randomized, double-masked, placebo-controlled, multicenter clinical trials. Participants Four hundred forty subjects (440 study eyes: 222 in the bromfenac group and 218 in the placebo group). Methods Two phase 3, prospective, randomized, double-masked, placebo-controlled clinical trials were conducted at 39 ophthalmology clinics in the United States. Subjects 18 years of age or older were randomized to receive either bromfenac 0.07% or placebo dosed once daily beginning 1 day before cataract surgery, on the day of surgery, and continuing for 14 days after surgery (for a total of 16 days). Subjects were evaluated on days 1, 3, 8, 15, and 22 after surgery. The primary efficacy end point was cleared ocular inflammation, as measured by the summed ocular inflammation score of zero (anterior chamber cell count = 0 and absence of flare) by day 15. Secondary end points included cleared ocular inflammation at day 15 and the number of subjects who were pain free at day 1. The data from the 2 clinical trials were integrated for analyses. Main Outcome Measures Summed ocular inflammation score and ocular pain. Results A significantly higher proportion of subjects treated with bromfenac 0.07% achieved complete clearance of ocular inflammation by day 15 and at day 15 compared with placebo (P < 0.0001). A statistically significantly higher proportion of subjects in the bromfenac 0.07% group were pain free at all study visits compared with those in the placebo group (P < 0.0001). Fewer subjects in the bromfenac group (3.2%) discontinued investigational product early because of a lack of efficacy than in the placebo group (23.9%; P < 0.0001). The incidence of adverse events was significantly lower in the bromfenac 0.07% group compared with the placebo group (P = 0.0041). Conclusions Bromfenac ophthalmic solution 0.07% dosed once daily was clinically safe and effective compared with placebo for the treatment of ocular inflammation and pain in subjects who had undergone cataract surgery and may be a beneficial addition to the current standard of care, which commonly includes ophthalmic antibiotics and corticosteroids. © 2014 by the American Academy of Ophthalmology. AD - J.A. Gow, Bausch and Lomb, Inc, 50 Technology Drive, Irvine, CA 92618-2301, United States AU - Walters, T. R. AU - Goldberg, D. F. AU - Peace, J. H. AU - Gow, J. A. C1 - prolensa DB - Embase Medline DO - 10.1016/j.ophtha.2013.07.006 IS - 1 KW - bromfenac eye drops nonsteroid antiinflammatory agent placebo prednisolone acetate aged anterior eye chamber article blurred vision cataract extraction cell count conjunctival hyperemia controlled study cornea edema drug efficacy drug safety eye inflammation eye pain female foreign body human implant incidence intention to treat analysis intraocular pressure abnormality lens implantation major clinical study male multicenter study ocular pruritus patient compliance phase 3 clinical trial photophobia posterior chamber lens priority journal prospective study randomized controlled trial prolensa LA - English M3 - Article N1 - L52768119 2013-09-12 2014-01-14 PY - 2014 SN - 0161-6420 1549-4713 SP - 25-33 ST - Bromfenac ophthalmic solution 0.07% dosed once daily for cataract surgery: Results of 2 randomized controlled trials T2 - Ophthalmology TI - Bromfenac ophthalmic solution 0.07% dosed once daily for cataract surgery: Results of 2 randomized controlled trials UR - https://www.embase.com/search/results?subaction=viewrecord&id=L52768119&from=export http://dx.doi.org/10.1016/j.ophtha.2013.07.006 VL - 121 ID - 460 ER - TY - JOUR AB - BACKGROUND: Capsular contracture is one of the most common complications associated with breast implants. While the cause of this process has not yet been elucidated, subclinical infection is a likely culprit. OBJECTIVES: The authors assess the hypothesis that a probable source of contamination is endogenous breast bacteria, likely originating in the ducts themselves and most concentrated near the nipple. METHODS: Twenty-five healthy patients presenting for routine reduction mammaplasty were recruited as study participants. Tissue samples were taken intraoperatively from the periareolar, inframammary, and axillary regions of each sampled breast. Specimens were then processed in the microbiology laboratory, and quantitative bacterial counts were obtained. RESULTS: Of the 50 breasts sampled, 19 yielded positive culture results, for a rate of 38%. There was a significant difference in the positive culture rate among all three sites, with increasing quantitative bacterial counts in the axillary, inframammary, and periareolar regions, respectively. The most commonly-identified organisms in this study included various species of Staphylococcus and Propionibacterium acnes, with S. epidermidis being the most common. CONCLUSIONS: The breast harbors significant endogenous bacteria that can become the source of spontaneous or postoperative infection. Positive intraoperative cultures with high quantitative counts suggest that breast tissue harbors more bacteria than normal skin flora. Routine perioperative antibiotic prophylaxis may be suboptimal for the prevention of foreign body seeding in this setting. Furthermore, bacterial concentrations are highest in areas with the most ductal tissue, namely the periareolar region. These findings may be helpful when considering which incision site to select for augmentation mammaplasty. AD - Division of Plastic Surgery, New York Presbyterian Hospital, Columbia University Medical Center, 161 Fort Washington Avenue, New York, NY 10032, USA. AN - 21908811 AU - Bartsich, S. AU - Ascherman, J. A. AU - Whittier, S. AU - Yao, C. A. AU - Rohde, C. DA - Sep DO - 10.1177/1090820x11417428 DP - NLM ET - 2011/09/13 IS - 7 KW - Breast/*microbiology Female Humans Implant Capsular Contracture/etiology Mammaplasty/adverse effects/*methods Nipples/*microbiology Propionibacterium/isolation & purification Staphylococcus/isolation & purification LA - eng N1 - 1527-330x Bartsich, Sophie Ascherman, Jeffrey A Whittier, Susan Yao, Caroline A Rohde, Christine Journal Article England Aesthet Surg J. 2011 Sep;31(7):802-6. doi: 10.1177/1090820X11417428. PY - 2011 SN - 1090-820x SP - 802-6 ST - The breast: a clean-contaminated surgical site T2 - Aesthet Surg J TI - The breast: a clean-contaminated surgical site VL - 31 ID - 113 ER - TY - JOUR AB - Toxic shock syndrome (TSS) is a severe, acute, toxin-mediated disease process characterized by fever, diffuse erythroderma, hypotension, multisystem organ dysfunction and desquamation of skin. TSS represents the most severe form of disease caused by exotoxin-producing strains of Streptococcus pyogenes and Staphylococcus aureus. Menstrual and non-menstrual TSS become significant causes of morbidity and mortality. As a result of public awareness and various campaigns, the majority of TSS cases tend to be non-menstrual related. The clinical course is fulminant and can result in abrupt decompensation and death. Management within the emergency department (ED) includes removal of the potential foreign body, fluid resuscitation, appropriate antibiotics, potential vasopressor support and possible surgical intervention. We present the unique case of a 16-year-old female competitive swimmer who presented to the ED twice, demonstrating the fulminant course of TSS. She initially presented with non-specific symptoms with an unremarkable evaluation. She returned within hours of discharge with an abrupt onset of diffuse macular erythroderma, placed on norepinephrine and was diagnosed with TSS secondary to a breast abscess. © 2019 The Author(s) 2019. Published by Oxford University Press. AD - Beaumont Hospital, Teaching Hospital of Michigan State University, Departments of Emergency Medicine and Infectious Disease, Farmington Hills, MI, United States Indiana University Health Ball Memorial Hospital, Department of Emergency Medicine, Muncie, IN, United States AU - Taylor, G. M. AU - Vieder, S. J. AU - Cooley, C. N. AU - Fan, W. C. AU - Alper, M. E. DB - Scopus DO - 10.1093/omcr/omz054 IS - 6 M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2019 SP - 288-291 ST - Breast abscess in a competitive high school swimmer: A case of toxic shock syndrome T2 - Oxford Medical Case Reports TI - Breast abscess in a competitive high school swimmer: A case of toxic shock syndrome UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85084312332&doi=10.1093%2fomcr%2fomz054&partnerID=40&md5=81e6e6087594e0c410ba3f3930e8255c VL - 2019 ID - 1009 ER - TY - JOUR AB - The influence of tethering silicon microelectrode arrays on the cortical brain tissue reaction was compared with that of untethered implants placed in the same location by identical means using immunoflourescent methods and cell type specific markers over indwelling periods of 1-4 weeks. Compared with untethered, freely floating implants, tethered microelectrodes elicited significantly greater reactivity to antibodies against ED1 and GFAP over time. Regardless of implantation method or indwelling time, retrieved microelectrodes contained a layer of attached macrophages identified by positive immunoreactivity against ED1. In the tethered condition and in cases where the tissue surrounding untethered implants had the highest levels of ED1+ and GFAP+ immunoreactivity, the neuronal markers for neurofilament 160 and NeuN were reduced. Although the precise mechanisms are unclear, the present study indicates that simply tethering silicon microelectrode arrays to the skull increases the cortical brain tissue response in the recording zone immediately surrounding the microelectrode array, which signals the importance of identifying this important variable when evaluating the tissue response of different device designs, and suggests that untethered or wireless devices may elicit less of a foreign body response. © 2007 Wiley Periodicals, Inc. AD - Keck Center for Tissue Engineering, Department of Bioengineering, University of Utah, Salt Lake City, UT 84112, United States Macromolecular Science and Engineering Center, Department of Materials Science and Engineering, University of Michigan, Ann Arbor, MI 48109, United States AU - Biran, R. AU - Martin, D. C. AU - Tresco, P. A. DB - Scopus DO - 10.1002/jbm.a.31138 IS - 1 KW - Foreign body response Implant Neuroprosthetic Silicon electrode Tissue response M3 - Article N1 - Cited By :224 Export Date: 10 November 2020 PY - 2007 SP - 169-178 ST - The brain tissue response to implanted silicon microelectrode arrays is increased when the device is tethered to the skull T2 - Journal of Biomedical Materials Research - Part A TI - The brain tissue response to implanted silicon microelectrode arrays is increased when the device is tethered to the skull UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-34250177246&doi=10.1002%2fjbm.a.31138&partnerID=40&md5=b2cb3fb7406f85eb3d793dc5448f1855 VL - 82 ID - 1561 ER - TY - JOUR AB - Bouveret's syndrome is a rare condition usually caused by a single large stone impacted in the duodenum. This is a cause of gastric outlet. Even if endoscopy is the mainstay of diagnosis, the radiographic examinations are also important too. Generally, the stones are too large to be removed endoscopically. Conservative endoscopic treatment should be attempted initially, and if it fails, surgical approach should be performed. AD - Unità di Gastroenterologia ed Endoscopia Digestiva, Ospedale Sandro Pertini, Via dei Monti Tiburtini, 00157, Rome, Italy Unit of Surgery, Sandro Pertini Hospital, Rome, Italy Unit of Radiology, Sandro Pertini Hospital, Rome, Italy AU - Zippi, M. AU - Di Stefano, P. AU - Manetti, G. AU - Febbraro, I. AU - Traversa, G. AU - Mazzone, A. M. AU - De Felici, I. AU - Mattei, E. AU - Occhigrossi, G. DB - Scopus IS - 5 KW - Bouveret's syndrome Endoscopy M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2009 SP - 367-369 ST - Bouveret' syndrome: Description of a case T2 - Clinica Terapeutica TI - Bouveret' syndrome: Description of a case UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-72049091743&partnerID=40&md5=b2055e0091e2831b4369f84230a27720 VL - 160 ID - 1490 ER - TY - JOUR AB - Gastrointestinal complications secondary to fish bone ingestion are rare, however important to recognize in timely manner to prevent morbidity and mortality. Diagnosis is often challenging in setting of non-specific and variable symptoms and lack of history of fish bone ingestion. Diagnostic imaging particularly computed tomography is crucial for diagnosis. However, emphasis should be given on identifying underlying cause of abdominal complications because fish bone is often missed unless specifically looked for. Identification of fish bone is essential for extraction of the inciting nidus. Emergency physician should be aware of this entity to identify it and triage the patients in timely manner. We describe here cases of sub-capsular liver abscess and acute cholecystitis caused by fish bone ingestion. The fish bone as a cause of these complication was initially missed in emergency. © 2019 Elsevier Inc. AD - Department of Radiology, St. Vincent's Medical Center, Bridgeport, CT, United States The Frank H. Netter MD School of Medicine at Quinnipiac University, North Haven, CT, United States Department of Medicine, St. Vincent's Medical Center, Bridgeport, CT, United States AU - Goyal, P. AU - Gupta, S. AU - Sapire, J. DB - Scopus DO - 10.1016/j.jemermed.2019.06.013 IS - 3 KW - acute cholecystitis fish bone liver abscess M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - e95-e97 ST - Bone Causing Abdominal Groans T2 - Journal of Emergency Medicine TI - Bone Causing Abdominal Groans UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069965046&doi=10.1016%2fj.jemermed.2019.06.013&partnerID=40&md5=076071fdb685e3b44c024ca2276ebbef VL - 57 ID - 998 ER - TY - JOUR AN - 105324343. Language: English. Entry Date: 20091113. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 4 KW - Knee Surgery -- Adverse Effects Retained Instruments Surgical Count Procedure Accountability Equipment Failure Evidence, Legal Malpractice Perioperative Nursing N1 - legal case. Journal Subset: Blind Peer Reviewed; Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Legal Case: Ripley v. Lanzer, WA-61952-7-1 (9/14/2009). NLM UID: 100936959. PMID: NLM19877407. PY - 2009 SN - 1528-848X SP - 1p-1p ST - Blade left in pt.: why didn't nurses notice bladeless scalpel? T2 - Nursing Law's Regan Report TI - Blade left in pt.: why didn't nurses notice bladeless scalpel? UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105324343&site=ehost-live&scope=site VL - 50 ID - 943 ER - TY - JOUR AB - Urinary tract calculi are fairly common, though bladder calculi are less common, accounting for only 5% of urinary tract calculi. Bladder calculi, particularly large bladder calculi, are usually associated with pathology in the urinary tract. Such pathologies include urethral strictures, bladder neck contractures, benign prostatic hypertrophy, neurogenic bladder and foreign bodies in the bladder. Bladder calculi are more common in men than in women. Bladder calculi causing bowel obstruction have been documented in the literature before but they remain very rare. © 2019 Author. This work is licensed under the Creative Commons Attribution 4.0 International License. AD - Klerksdorp Tshepong Hospital Complex, University of Witwatersrand, Benji Oliphant Street, Klerksdorp, North, West 2570, South Africa AU - Bellomo, A. AU - Kwati, M. AU - Monzon, J. AU - Ogunrombi, B. DB - Scopus DO - 10.4314/aas.v16i2.9 IS - 2 KW - Bladder calculus Large bowel obstruction M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 82-83 ST - Bladder calculus causing large bowel obstruction T2 - Annals of African Surgery TI - Bladder calculus causing large bowel obstruction UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071438968&doi=10.4314%2faas.v16i2.9&partnerID=40&md5=233bcb25e5f94c4ef083807b1bcbbc54 VL - 16 ID - 1042 ER - TY - JOUR AB - In spite of careful intraoperative precautions and gauze counts, mistakes can still occur during surgery. In the case reported, a retained gauze leaved during a surgical approach for removing a solid-cystic papillary tumor localized in the pancreatic tail, caused both persistent abdominal discomfort and the presence of an abdominal cystic lesion at imaging techniques. When a previous operative history is present, a foreign body should be taken into account in the differential diagnosis of a patient with an intra-abdominal cystic mass. Finally, radio-opaque marker should be routinely used by surgeons in order to reach a correct diagnosis in operated patients having retained gauze. AD - Department of Digestive Diseases and Internal Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna. Bologna, Italy. AN - 20818122 AU - Zucchini, G. AU - Pezzilli, R. AU - Ricci, C. AU - Casadei, R. AU - Santini, D. AU - Calculli, L. AU - Corinaldesi, R. DA - Sep 6 DP - NLM ET - 2010/09/08 IS - 5 KW - Abdomen/surgery Abdominal Cavity/diagnostic imaging/*pathology Adenocarcinoma, Papillary/surgery Adult Cysts/*diagnostic imaging/surgery Diagnosis, Differential Female Foreign Bodies/diagnosis/surgery Humans Pancreatic Neoplasms/surgery Postoperative Complications/etiology Radiography, Abdominal LA - eng N1 - 1590-8577 Zucchini, Giorgia Pezzilli, Raffaele Ricci, Claudio Casadei, Riccardo Santini, Donatella Calculli, Lucia Corinaldesi, Roberto Case Reports Journal Article Italy JOP. 2010 Sep 6;11(5):480-1. PY - 2010 SN - 1590-8577 SP - 480-1 ST - A bizarre abdominal cystic lesion T2 - Jop TI - A bizarre abdominal cystic lesion VL - 11 ID - 101 ER - TY - JOUR AB - OBJECTIVE:: The aim of this study was to investigate biomechanical and immunogenic properties of spider silk meshes implanted as fascia replacement in a rat in vivo model. BACKGROUND:: Meshes for hernia repair require optimal characteristics with regard to strength, elasticity, and cytocompatibility. Spider silk as a biomaterial with outstanding mechanical properties is potentially suitable for this application. METHODS:: Commercially available meshes used for hernia repair (Surgisis and Ultrapro) were compared with handwoven meshes manufactured from native dragline silk of Nephila spp. All meshes were tied onto the paravertebral fascia, whereas sham-operated rats were sutured without mesh implantation. After 4 or 14 days, 4 weeks, and 4 or 8 months, tissue samples were analyzed concerning inflammation and biointegration both by histological and biochemical methods and by biomechanical stability tests. RESULTS:: Histological sections revealed rapid cell migration into the spider silk meshes with increased numbers of giant cells compared with controls with initial decomposition of silk fibers after 4 weeks. Four months postoperatively, spider silk was completely degraded with the formation of a stable scar verified by constant tensile strength values. Surgisis elicited excessive stability loss from day 4 to day 14 (P < 0.001), with distinct inflammatory reaction demonstrated by lymphocyte and neutrophil invasion. Ultrapro also showed decreasing strength and poor elongation behavior, whereas spider silk samples had the highest relative elongation (P < 0.05). CONCLUSIONS:: Hand-manufactured spider silk meshes with good biocompatibility and beneficial mechanical properties seem superior to standard biological and synthetic meshes, implying an innovative alternative to currently used meshes for hernia repair. © 2013 by Lippincott Williams & Wilkins. AD - Department of Plastic, Hand and Reconstructive Surgery, Medical School Hannover, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany Department of Plastic, Reconstructive and Aesthetic Surgery, Klinikum Bremen-Mitte, University of Göttingen, Bremen, Germany AU - Schäfer-Nolte, F. AU - Hennecke, K. AU - Reimers, K. AU - Schnabel, R. AU - Allmeling, C. AU - Vogt, P. M. AU - Kuhbier, J. W. AU - Mirastschijski, U. DB - Scopus DO - 10.1097/SLA.0b013e3182917677 IS - 4 KW - Biomaterial degradation hernia mesh immune response spider silk M3 - Article N1 - Cited By :21 Export Date: 10 November 2020 PY - 2014 SP - 781-792 ST - Biomechanics and biocompatibility of woven spider silk meshes during remodeling in a rodent fascia replacement model T2 - Annals of Surgery TI - Biomechanics and biocompatibility of woven spider silk meshes during remodeling in a rodent fascia replacement model UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84895930977&doi=10.1097%2fSLA.0b013e3182917677&partnerID=40&md5=3fa1f496d567052783d8162ef503d070 VL - 259 ID - 1298 ER - TY - JOUR AB - INTRODUCTION: Basicervical femoral neck fractures are challenging fractures in geriatric populations. The goal of this study was to determine whether compression hip screw (CHS) constructs are superior to cephalomedullary constructs for the treatment of basicervical femoral neck fractures. METHODS: Thirty cadaver femurs were osteotomized and received a CHS with derotation screw, a long cephalomedullary nail (long Gamma nail), or a short cephalomedullary nail (short Gamma nail). All constructs were loaded dynamically in compression until dynamic failure. RESULTS: All failed CHS constructs demonstrated superior femoral head cutout. In the long Gamma nail and short Gamma nail groups, constructs failed by nail cutout through the medial wall of the trochanter or rotationally. Normalized fluoroscopic distance was found to increase markedly with an increasing cycle count when considering all treatment groups. CONCLUSIONS: Given our results and those of previous studies, we could not determine superiority of one implant and recommend that surgeons select fixation constructs based on the individual patient's anatomy and the surgeon's comfort with the implant. AU - Johnson, J. AU - Deren, M. AU - Chambers, A. AU - Cassidy, D. AU - Koruprolu, S. AU - Born, C. DB - Medline DO - 10.5435/JAAOS-D-17-00155 IS - 1 KW - aged biomechanics bone density bone nail bone screw cadaver compressive strength device failure analysis devices diagnostic imaging female femoral neck fracture fluoroscopy foreign body human intramedullary nailing procedures very elderly LA - English M3 - Article N1 - L625619677 2018-12-28 2019-02-12 PY - 2019 SN - 1940-5480 SP - e41-e48 ST - Biomechanical Analysis of Fixation Devices for Basicervical Femoral Neck Fractures T2 - The Journal of the American Academy of Orthopaedic Surgeons TI - Biomechanical Analysis of Fixation Devices for Basicervical Femoral Neck Fractures UR - https://www.embase.com/search/results?subaction=viewrecord&id=L625619677&from=export http://dx.doi.org/10.5435/JAAOS-D-17-00155 VL - 27 ID - 324 ER - TY - JOUR AB - The cellular and tissue responses to 3 dental cements were studied by 2 methodologies, the connective tissue implantation technique (CTI), recommended by the ADA, and the peritoneal cavity implantation technique (PCI), which has emerged as a method to quantitatively study the cellular response to implanted materials. A mixed inflammatory cell response consisting of neutrophils and macrophages occurred at most of the time periods for all the cements examined in the CTI study. Similar cell populations, including lymphocytes, were observed with the PCI study using differential staining techniques. The histopathological observations from both procedures were similar. Each cement elicited a chronic foreign body reaction containing few chronic cells and mature fibroblastic activity. The intensity of the observed tissue reactions for each cement, as determined by capsule thickness in the CTI study and the overall cell counts in the PCI study, did not differ significantly with increasing time. The cellular and connective tissue reactions to the zinc hexyl vanillate (ZHV) cement approximated those of zinc oxide-eugenol (ZOE) and zinc phosphate (ZP) cements for both methodologies utilized in this work. While similar histopathological results were obtained for the implantation of cements using both methodologies, the PCI technique offers a more thorough investigation of cellular and tissue responses to implanted materials. In addition to histopathological evaluations, the PCI techniques allows quantitative investigation of the specific cells responding to the implants, and provides a mechanism, using chemical analysis techniques, to quantify the concentration of specific degradative products within the retrieved cells and host tissue. Finally, the results from these 2 methodologies demonstrated the acceptable biological performance of ZHV cement compared with the clinically acceptable ZP and ZOE cement formulations. © 1988 Munksgaard International Publishers Ltd. AD - Department of Materials Science, Medical University of South Carolina, Charleston, SC, United States Dental and Medical Materials, National Bureau of Standards, Gaithersburg, MD, United States AU - Keller, J. C. AU - Hammond, B. D. AU - Kowalyk, K. K. AU - Brauer, G. M. DB - Scopus DO - 10.1016/S0109-5641(88)80047-2 IS - 6 KW - dental cement zinc hexyl vanillate zinc oxide-eugenol zinc phosphate M3 - Article N1 - Export Date: 10 November 2020 PY - 1988 SP - 341-350 ST - Biological evaluations of zinc hexyl vanillate cement using two in vivo test methods T2 - Dental Materials TI - Biological evaluations of zinc hexyl vanillate cement using two in vivo test methods UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024147457&doi=10.1016%2fS0109-5641%2888%2980047-2&partnerID=40&md5=67a84b7a103a84e374587d6685a0a4c5 VL - 4 ID - 1745 ER - TY - JOUR AB - Biologic reactivity to suture materials can have an effect on patient outcomes. The goal of this study was to determine the histologic response to 8 commonly used orthopedic sutures-Ethibond (Ethicon, Somerville, New Jersey), Ticron (Tyco, Waltham, Massachusetts), HiFi (Linvatec, Largo, Florida), Ultrabraid (Smith & Nephew, Memphis, Tennessee), MaxBraid (Biomet, Warsaw, Indiana), Orthocord (Mitek, Raynham, Massachusetts), MagnumWire (Opus Medical, San Juan Capistrano, California), and FiberWire (Arthrex, Naples, Florida)-using a rabbit model. The suture granuloms were evaluated at 30, 60, and 120 days with measurement of the fibrous capsule, the number of giant cells in and near the capsule, and the overall inflammatory grade: 1 (mild), 2 (moderate), and 3 (severe). MagnumWire and Ticron sutures initiated a more intense inflammatory reaction when compared to the other sutures. By 120 days, MagnumWire (P=.0297) and Ticron (P=.1855) had fewer giant cells at the soft tissue-suture interface, fewer giant cells within the capsule (P=.0074 and P=.0377, respectively), and the greatest capsular thickness of all suture types (P<.0001 and P=.1378, respectively). Differences exist between the biologic reactivity of commonly used orthopedic sutures that may be attributable to their material composition and/or braid characteristics. In comparison to other high-strength sutures, MagnumWire and Ticron stimulated a more intense foreign body inflammatory response. Copyright © 2009 SLACK Incorporated. All rights reserved. AD - William Beaumont Army Medical Center, El Paso, TX, United States AU - Carr, B. J. AU - Ochoa, L. AU - Rankin, D. AU - Owens, B. D. DB - Scopus DO - 10.3928/01477447-20090922-11 IS - 11 M3 - Article N1 - Cited By :31 Export Date: 10 November 2020 PY - 2009 ST - Biologic response to orthopedic sutures: A histologic study in a rabbit model T2 - Orthopedics TI - Biologic response to orthopedic sutures: A histologic study in a rabbit model UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-70450200589&doi=10.3928%2f01477447-20090922-11&partnerID=40&md5=b10bc4450f7d2266937cd6a5cd713987 VL - 32 ID - 1484 ER - TY - JOUR AB - Background: The biocompatibility of chitosan in common tissues has already been proved. However, there are few reports on the biocompatible features of it in brain tissues. Objective: To explore the biocompatibility of chitosan in brain tissues in order to provide slow released macromolecule carrier for clinically used chemotherapy. Design: Randomized controlled study. Setting and participants: Experiment site: Operation room of experiment centre, Wuhan University. Thirty-two SD rats were chosen and divided into experimental group and control group by simple random method. Methods: Chitosan and gelfoam were implanted into rats' skull by operation. Then observed the behavior changes and local histologic reaction in the 3rd, 7th, 14th and 30th day (haematoxylin-eosin dye). Main outcome measures: Inflammatory cells counting of different materials in different stages. Results: There was no obvious behavior change of all rats. The histological reactions in the 3rd, 7th, 14th, 30th day were similar with the foreign body reaction caused by gelfoam. There was significant difference on counting of neutrophilic granulocyte and lymphocyte between experimental group and control group within the 3 mm area of implanted materials in the 7th day(t = 6.98, 3.311, P = 0.001, 0.019). There was also significance difference on those cell counting between two groups in the 14th day (t = 6.454, 4.899, P = 0.001, 0.003). In the 30th day, there was difference on counting of lymphocyte and fibrocyte between two groups (t = 3.767, 5.019, P = 0.010, 0.006). Conclusion: There is very good biocompatibility of chitosan with brain tissue. It can be degraded safely. AD - Department of General Surgery, Wuhan Gen. Hosp. of Guangzhou Comm., Wuhan 430070 Hubei Province, China Department of Neurosurgery, People's Hosp. of Wuhan University, Wuhan 430060 Hubei Province, China AU - Zhou, T. AU - Zhou, B. AU - Huang, S. L. DB - Scopus IS - 22 M3 - Article N1 - Export Date: 10 November 2020 PY - 2004 SP - 4640-4641 ST - Biocompatible features of chitosan in brain tissues T2 - Chinese Journal of Clinical Rehabilitation TI - Biocompatible features of chitosan in brain tissues UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-4944252404&partnerID=40&md5=b451c16bb4b2db5c2b2de8b4f03f9e2b VL - 8 ID - 1625 ER - TY - JOUR AB - The biocompatibility of a 3 mm band made of polyethylene terephthalate (Trevira® hochfest) has been tested in an experimental study within right knee joints of 60 sheep. After transsecting the anterior cruciate ligament (ACL), two randomized groups were formed. In group I, the ACL was repaired according to the Marshall technique whilst in group II an additional 3 mm polyethylene terephthalate (PET) augmentation band was implanted using the through-the-condyle (TTC) procedure. To assess the biocompatibility of the augmentation device the knee joints of both groups were punctured and the synovial fluids were analyzed before, as well as 2, 6, 16, 26, and 52 weeks after the operation. In addition, the histologic appearance of excised suprapatellar pouches and ipsilateral inguinal and popliteal lymphatic noduli were examined. Comparing both groups no significant differences were found neither before nor after the augmented and non-augmented ACL repair. No pathological increase in the total protein concentration occurred after operation and no significant differences versus the preoperative analysis were found. No synovitis signalling a decrease in the glucose concentration was observed. The cytological examination revealed no increase of the leukocyte cell count results. Within the synovial specimen neither free nor phagocytosed PET wearparticles could be detected. In groups I and II the histological appearance of excised popliteal and inguinal lymphatic noduli showed a normal result. In 25% of the PET augmented ACL repairs, a slight concentration of PET wearparticles and solitary, multinuclear giant foreign body cells could be seen in the histological preparations of suprapatellar pouches. The biocompatibility of a 3 mm band made of polyethylene terephthalate (Trevira hochfest) has been tested in an experimental study within right knee joints of 60 sheep. After transsecting the anterior cruciate ligament (ACL), two randomized groups were formed. In group I, the ACL was repaired according to the Marshall technique whilst in group II an additional 3 mm polyethylene terephthalate (PET) augmentation band was implanted using the through-the-condyle (TTC) procedure. To assess the biocompatibility of the augmentation device the knee joints of both groups were punctured and the synovial fluids were analyzed before, as well as 2, 6, 16, 26, and 52 weeks after the operation. In addition, the histologic appearance of excised suprapatellar pouches and ipsilateral inguinal and popliteal lymphatic noduli were examined. Comparing both groups no significant differences were found neither before nor after the augmented and non-augmented ACL repair. No pathological increase in the total protein concentration occurred after operation and no significant differences versus the preoperative analysis were found. No synovitis signalling a decrease in the glucose concentration was observed. The cytological examination revealed no increase of the leukocyte cell count results. Within the synovial specimen neither free nor phagocytosed PET wearparticles could be detected. In groups I and II the histological appearance of excised popliteal and inguinal lymphatic noduli showed a normal result. In 25% of the PET augmented ACL repairs, a slight concentration of PET wearparticles and solitary, multinuclear giant foreign body cells could be seen in the histological preparations of suprapatellar pouches. AD - Department of Traumatology, Vienna Univ. School of Medicine, Waehringer Guertel 18-20, A-1090 Vienna, Austria Department of Biomedical Research, Vienna Univ. School of Medicine, Waehringer Guertel 18-20, A-1090 Vienna, Austria AU - Seitz, H. AU - Marlovits, S. AU - Schwendenwein, I. AU - Müller, E. AU - Vécsei, V. DB - Scopus DO - 10.1016/S0142-9612(97)00201-9 IS - 1-3 KW - Anterior cruciate ligament repair Leukocytes Polyethylene terephthalate augmentation device Synovial fluid M3 - Article N1 - Cited By :40 Export Date: 10 November 2020 PY - 1998 SP - 189-196 ST - Biocompatibility of polyethylene terephthalate (Trevira® hochfest) augmentation device in repair of the anterior cruciate ligament T2 - Biomaterials TI - Biocompatibility of polyethylene terephthalate (Trevira® hochfest) augmentation device in repair of the anterior cruciate ligament UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031841064&doi=10.1016%2fS0142-9612%2897%2900201-9&partnerID=40&md5=17a4179daaf03a45e146a12a05085949 VL - 19 ID - 1701 ER - TY - JOUR AB - PURPOSE: To determine the foreign-body response to three intraocular lens (IOL) biomaterials (poly[methyl methacrylate] [PMMA], silicone, and AcrySof) and use this as an indicator of their comparative biocompatibility postoperatively within the eye. SETTING: A British teaching hospital eye department. METHODS: Ninety eyes were prospectively randomized to receive a PMMA, silicone, or AcrySof IOL. All lenses had 6.0 mm optics with PMMA haptics. A standardized surgical protocol was performed by a single surgeon using an extracapsular technique with capsulorhexis; eyes that experienced a surgical complication were excluded. All patients had standardized postoperative medication and follow-up. Specular microscopy of the anterior IOL surface was carried out after pupil dilation on days 1, 7, 30, 90, 180, 360, and 720 to assess small cell and giant cell reactions. RESULTS: All three IOL types produced a mild degree of nonspecific foreign-body response, which resolved over the study period without detrimental effect. The silicone group had significantly higher small cell counts than the PMMA and AcrySof groups (P = .02); the AcrySof group had significantly lower giant cell counts than the other two groups (P = .003). CONCLUSION: The three IOL types were sufficiently biocompatible to function in normal eyes with age-related cataracts. However, AcrySof IOLs were associated with lower giant cell counts than PMMA and silicone IOLs and might produce better results in eyes with pre-existing blood-aqueous barrier damage. AD - Department of Ophthalmology, St. Thomas' Hospital, London, United Kingdom. AN - 9559472 AU - Hollick, E. J. AU - Spalton, D. J. AU - Ursell, P. G. AU - Pande, M. V. DA - Mar DO - 10.1016/s0886-3350(98)80324-6 DP - NLM ET - 1998/04/29 IS - 3 KW - Acrylates/*adverse effects Aged Aged, 80 and over Biocompatible Materials/*adverse effects Capsulorhexis Cell Count Female Follow-Up Studies Foreign-Body Reaction/*etiology/pathology Giant Cells, Foreign-Body/pathology Humans *Lenses, Intraocular/adverse effects Macrophages/pathology Male Middle Aged Polymethyl Methacrylate/*adverse effects Prospective Studies Silicone Elastomers/*adverse effects LA - eng N1 - Hollick, E J Spalton, D J Ursell, P G Pande, M V Clinical Trial Comparative Study Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't United States J Cataract Refract Surg. 1998 Mar;24(3):361-6. doi: 10.1016/s0886-3350(98)80324-6. PY - 1998 SN - 0886-3350 (Print) 0886-3350 SP - 361-6 ST - Biocompatibility of poly(methyl methacrylate), silicone, and AcrySof intraocular lenses: randomized comparison of the cellular reaction on the anterior lens surface T2 - J Cataract Refract Surg TI - Biocompatibility of poly(methyl methacrylate), silicone, and AcrySof intraocular lenses: randomized comparison of the cellular reaction on the anterior lens surface VL - 24 ID - 26 ER - TY - JOUR AB - PURPOSE: We investigated the biocompatibility of n-butyl-2-cyanoacrylate (NBCA) in the cervical deep tissues of rats to assess its biocompatibility. METHODS: A total of 30 Sprague-Dawley rats were injected with NBCA. After 30, 90, 180, and 360 days, cubes of tissue (1 cm × 1 cm × 1 cm) surrounding the NBCA and normal tissue from the other side of the neck were excised from each rat. The adhesion of NBCA to adjacent structures was examined histologically. Cells were counted per high-power field (HPF), and fibrosis was graded with the measurement of fibrotic thickening. RESULTS: All animals displayed normal behavior without any symptoms of distress throughout the study. There was no recognizable inflammatory reaction, foreign body reaction, or fibrosis in the 30 control samples. The analyses of experimental samples showed significantly decreased inflammatory cell counts over time (lymphoplasma cell count decreased from 100 (range, 70-100) to 30 (range, 30-50) per HPF, P = 0.010; neutrophil count decreased from 2 (range, 2-30) to 0 (range, 0-2) per HPF, P = 0.017). However, there was no significant difference in the number of multinuclear giant cells throughout the study period (a decrease from 22 [range, 16-34] to 16 [range, 12-22] per HPF, P = 0.287). The level of fibrosis was Common Toxicity Criteria ver. 4.0 Grade 1 without further thickening (P = 0.600). However, maturation of fibrosis progressed gradually. CONCLUSION: NBCA was biologically tolerable in the cervical deep tissues of rats. However, precautions are needed with respect to preventing a sustained foreign body reaction and fibrosis. AD - Department of Surgery, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea. Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Korea. Department of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea. Department of Pathology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea. Department of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea. AN - 30941319 AU - Suh, Y. J. AU - Yu, H. W. AU - Kim, S. J. AU - Choe, J. Y. AU - Park, H. J. AU - Choi, J. Y. AU - Lee, K. E. C2 - PMC6444043 DA - Apr DO - 10.4174/astr.2019.96.4.162 DP - NLM ET - 2019/04/04 IS - 4 KW - Biocompatible materials Chyle Cyanoacrylate Neck dissection was reported. LA - eng N1 - 2288-6796 Suh, Yong Joon Yu, Hyeong Won Kim, Su-JIn Choe, Ji-Young Park, Hyo Jin Choi, June Young Orcid: 0000-0001-9990-607x Lee, Kyu Eun Journal Article Ann Surg Treat Res. 2019 Apr;96(4):162-168. doi: 10.4174/astr.2019.96.4.162. Epub 2019 Mar 28. PY - 2019 SN - 2288-6575 (Print) 2288-6575 SP - 162-168 ST - Biocompatibility of n-butyl-2-cyanoacrylate (Histoacryl) in cervical structures of rats: prospective in vivo study T2 - Ann Surg Treat Res TI - Biocompatibility of n-butyl-2-cyanoacrylate (Histoacryl) in cervical structures of rats: prospective in vivo study VL - 96 ID - 226 ER - TY - JOUR AB - Adipose tissue engineering is considered as a promising treatment for repairing soft tissue defects. The decellularized extracellular matrix (ECM) is becoming the research focus in tissue engineering for its tissue specificity. In this study, the human adipose tissue liposucted from healthy people were decellularized by a series of mechanical, chemical, and enzymatic methods. The components of cell and lipid were effectively removed, whereas the collagens and other ingredients in adipose tissue were retained in the human decellularized adipose tissue (hDAT). Then the extracted hDAT was further fabricated into injectable hydrogel, which could be self-assembled to form gel under certain condition. The hDAT hydrogel was nontoxic to human adipose-derived stem cells (ADSCs) and could spontaneously induce adipogenic differentiation in vitro. It was highly biocompatible and could not cause inflammation and rejection after being implanted subcutaneously. The hDAT hydrogel developed in this study will be one of the available choices for soft tissue enlargement and cosmetic fillers because of its noninvasive in collection and implantation process. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 107B: 1684–1694, 2019. © 2018 Wiley Periodicals, Inc. AD - Department of Plastic Surgery, Shengjing Hospital, Affiliated Hospital of China Medical University, Shenyang, Liaoning 110004, China Department of Tissue Engineering, School of Fundamental Science, China Medical University, Shenyang, Liaoning 110122, China AU - Zhao, Y. AU - Fan, J. AU - Bai, S. DB - Scopus DO - 10.1002/jbm.b.34261 IS - 5 KW - decellularized adipose tissue extracellular matrix hydrogel scaffolds tissue engineering M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2019 SP - 1684-1694 ST - Biocompatibility of injectable hydrogel from decellularized human adipose tissue in vitro and in vivo T2 - Journal of Biomedical Materials Research - Part B Applied Biomaterials TI - Biocompatibility of injectable hydrogel from decellularized human adipose tissue in vitro and in vivo UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85055539196&doi=10.1002%2fjbm.b.34261&partnerID=40&md5=f05646d1daccddd4ed0583b851cfb872 VL - 107 ID - 1006 ER - TY - JOUR AB - Background: The aim of this study was to evaluate the mid-term biocompatibility of a new x-shaped implant made of zirconium in an animal model of glaucoma surgery. Methods: Preoperatively, ultrasound biomicroscopy (UBM), intraocular pressure (IOP) and outflow facility (OF) data were acquired. Upon surgery, one eye was chosen randomly to receive an implant, while the other received none. Ten rabbits went through a 1-, 2-, 3-, 4- and 6-month follow-up. IOP was measured regularly, UBM performed at 1, 3 and 6 months after surgery. At the end of the follow-up, OF was again measured. Histology sections were analyzed. Results: For both groups IOP control was satisfactory, while OF initially increased at month 1 to resume preoperative values thereafter. Eyes with implants had larger filtration blebs which decreased faster than in eyes without the implant. Drainage vessel density, inflammatory cell number and fibrosis were higher in tissues near the implant. Conclusions: The zirconium implant initially promoted the positive effects of the surgery (IOP control, OF increase). Nevertheless, after several months, foreign body reactions and fibrosis had occurred on some implants that restrained the early benefit of such a procedure. Modifications of the zirconium implant geometry could enhance the overall success rate. © Springer-Verlag 2008. AD - Glaucoma Unit, Jules Gonin Eye Hospital, University of Lausanne, Avenue de France 15, CH-1004 Lausanne, Switzerland AU - Basso, A. AU - Roy, S. AU - Mermoud, A. DB - Scopus DO - 10.1007/s00417-008-0782-y IS - 6 KW - Aqueous humour Drainage device Filtering surgery Glaucoma Tonometry Ultrasonography M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2008 SP - 849-855 ST - Biocompatibility of an x-shaped zirconium implant in deep sclerectomy in rabbits T2 - Graefe's Archive for Clinical and Experimental Ophthalmology TI - Biocompatibility of an x-shaped zirconium implant in deep sclerectomy in rabbits UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-43249105930&doi=10.1007%2fs00417-008-0782-y&partnerID=40&md5=1631eb95a94ebae4c729a5f050a11633 VL - 246 ID - 1526 ER - TY - JOUR AB - A novel poly(butyl succinate) (PBS) and polylactic acid (PLA) blend with the favorable mechanical and degradable properties may be applied in the field of biomedicine. The purpose of this study was to investigate the in vitro and in vivo biocompatibilities of the PBS/PLA blend for future application. For in vitro analysis, the L929 fibroblasts and bone marrow stem cells (BMSCs) had been chosen to assess the cytocompatibility. The extract of PBS/PLA blend did not show any cytotoxicity to the L929 and BMSCs by Cell Counting Kit-8 and lactate dehydrogenase assays. Meanwhile, the results of the cytocompatibility showed no difference between the PBA/PLA blend and pure PLA and PBS. Subsequently, they were implanted into rats subcutaneously for in vivo study. It was found that similar with pure PLA and PBS, PBS/PLA blend caused the mild inflammation and foreign body reaction in rats during the consecutive 9 month implantation. However, the status of fibrosis surrounding PBS/PLA blend was superior to the pure PLA and PBS. In all, it was demonstrated that the novel PBS/PLA blend had excellent biocompatibilities in vitro and in vivo. Copyright © 2012 by the American Society for Artificial Internal. AD - Department of Surgery, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, China Clinical Laboratory, Shijitan Hospital, Capital Medical University, Beijing, China AU - Kun, H. AU - Wei, Z. AU - Xuan, L. AU - Xiubin, Y. DB - Scopus DO - 10.1097/MAT.0b013e31824709ee IS - 3 M3 - Article N1 - Cited By :7 Export Date: 10 November 2020 PY - 2012 SP - 262-267 ST - Biocompatibility of a novel poly(butyl succinate) and polylactic acid blend T2 - ASAIO Journal TI - Biocompatibility of a novel poly(butyl succinate) and polylactic acid blend UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84860743243&doi=10.1097%2fMAT.0b013e31824709ee&partnerID=40&md5=7fdfc34190de38976da3af1bd1744e2f VL - 58 ID - 1371 ER - TY - JOUR AB - The failure of facial prostheses is caused by limitations in the properties of existing materials, especially the biocompatibility. This study aimed to evaluate the biocompatibility of maxillofacial silicones in subcutaneous tissue of rats. Thirty Wistar rats received subcutaneous implants of 3 maxillofacial silicone elastomers (LIM 6050, MDX 4-4210, and industrial Silastic 732 RTV). A histomorphometric evaluation was conducted to analyze the biocompatibility of the implants. Eight areas of 60.11 mm from the surgical pieces were analyzed. Mesenchymal cells, eosinophils, and foreign-body giant cells were counted. Data were submitted to analysis of variance and Tukey test. Initially, all implanted materials exhibited an acceptable tissue inflammatory response, with tissue reactions varying from light to moderate. Afterward, a fibrous capsule around the silicone was observed. The silicones used in the current study presented biocompatibility and can be used for implantation in both medical and dental areas. Their prosthetic indication is conditioned to their physical properties. Solid silicone is easier to adapt and does not suffer apparent modifications inside the tissues. Copyright © 2011 by Mutaz B. Habal, MD. AD - Department of Pediatric Dentistry, Araçatuba Dental School-Univ Estadual Paulista, Araçatuba, Brazil Department of Pathology and Clinical Propaedeutics, Araçatuba Dental School-Univ Estadual Paulista, Araçatuba, Brazil Institute of Health Research, Araçatuba Dental School-Univ Estadual Paulista, Araçatuba, São Paulo, Brazil Department of Dental Materials and Prosthodontics, Araçatuba Dental School-Univ Estadual Paulista, Araçatuba, São Paulo, Brazil Araçatuba Dental School-Univ Estadual Paulista-UNESP, Rua Jose Bonifacio, 1193, Vila Mendonca, Araçatuba, São Paulo, CEP 16015-050, Brazil AU - França, D. C. C. AU - De Castro, A. L. AU - Soubhia, A. M. P. AU - Tucci, R. AU - De Aguiar, S. M. H. C. A. AU - Goiato, M. C. DB - Scopus DO - 10.1097/SCS.0b013e31820f367b IS - 3 KW - biocompatibility connective tissue Facial silicone inflammation M3 - Article N1 - Cited By :9 Export Date: 10 November 2020 PY - 2011 SP - 837-840 ST - Biocompatibility evaluation of 3 facial silicone elastomers T2 - Journal of Craniofacial Surgery TI - Biocompatibility evaluation of 3 facial silicone elastomers UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79958000707&doi=10.1097%2fSCS.0b013e31820f367b&partnerID=40&md5=635638df56a2cf89c1324f371dc5cfde VL - 22 ID - 1423 ER - TY - JOUR AB - Filler materials for medical use present limits, such as the induction of chronic inflammation and fibrosis. In the search for synthetic materials with improved biocompatible properties, a new polyacrylamide hydrogel, Aquamid (Contura SA, Montreux, Switzerland), has been investigated in preclinical systems. In cell cultures (endothelial cells and fibroblast), no or only transient biological effects were associated with 10% Aquamid exposure. The Aquamid-host interactions were examined in mice (10 mice per group) implanted subcutaneously or in the mammary fat pad with a very large volume (1.5 ml) of the material. Blood analysis, performed after 15 and 94 days (five mice per time for each group) to detect acute or late manifestations of toxicity, did not reveal relevant abnormalities in either group of Aquamid-bearing mice compared with control mice, except for a transient thrombocytopenia and a mild leukocytosis. Histological analysis of the pellet showed the presence of a thin, poorly vascularized cyst wall in implants. Only mild mesenchymal reparative and inflammatory processes were observed, even at longer observation times (more than 400 days). No alterations in any organ were detected. Despite the large volume implanted (approximately 5 percent of mouse body weight), the Aquamid pellet maintained its original size and shape without spreading or sticking to surrounding tissues. In conclusion, the study indicated a good tolerability of the new biopolymer in preclinical systems. The clinical utility of this new compound, if confirmed by clinical randomized trials showing its atoxic properties, could be in the field of aesthetic plastic surgery as a filler material for body contouring and in reconstructive surgery and above all in cancer patients to restore surgical defects. AD - Ist. per lo Naz. Stud./Cura Tumori, Univ.' Statale degli Studi di Milano, Italy Istituto Nazionale Tumori, Via Venezian 1, 20133 Milan, Italy AU - Zarini, E. AU - Supino, R. AU - Pratesi, G. AU - Laccabue, D. AU - Tortoreto, M. AU - Scanziani, E. AU - Ghisleni, G. AU - Paltrinieri, S. AU - Tunesi, G. AU - Nava, M. DB - Scopus DO - 10.1097/01.PRS.0000133425.22598.D0 IS - 4 M3 - Article N1 - Cited By :58 Export Date: 10 November 2020 PY - 2004 SP - 934-942 ST - Biocompatibility and tissue interactions of a new filler material for medical use T2 - Plastic and Reconstructive Surgery TI - Biocompatibility and tissue interactions of a new filler material for medical use UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-20144381461&doi=10.1097%2f01.PRS.0000133425.22598.D0&partnerID=40&md5=58f9adf77b7f5a2ece896b63722ec48c VL - 114 ID - 1621 ER - TY - JOUR AB - The aim of this study was to evaluate the safety and tissue compatibility of an injectable biodegradable poly(ester-anhydride) copolymer of ricinoleic acid (RA) and sebacic acid (SA) in rats. The absorbable biomaterial containing 70% w/w of RA and 30% w/w of SA [P(SA-RA) 3:7] was implanted in rats in two separate studies: (1) at high doses subcutaneously (SC) and intramuscularly (IM) simultaneously into the same animal and (2) intracranially (IC). The safety was established in the highdose administration experiment. No systemic tissue damage, polymer-related lesions, or abnormalities could be detected in the animals. The histopathological evaluation of the SC and IM P(SA-RA) 3:7 implanted sites suggested a typical foreign body reaction (FBR) to biomaterials, and was characterized by excellent tissue repair and good tissue tolerance. In the second experiment, no neurological deficits or behavior changes suggestive of systemic or localized toxicity were observed in the animals implanted IC with the polymer. Only minimal, well-demarcated inflammatory response was observed on days 14 and 21 and consisted of glia cells. No abnormalities were noted in the brain tissue parenchyma located further from the edges of the implant. These results demonstrated that the P(SA-RA) 3:7 copolymer was tolerated well by the animals and compatible with rat subcutaneous, muscle and brain tissues. The biodegradable polymeric system described here could be used as a scaffold for varied applications in localized and sustained delivery of therapeutic agents. © 2009 Wiley Periodicals, Inc. AD - Department of Medicinal Chemistry and Natural Products, School of Pharmacy-Faculty of Medicine, Hebrew University of Jerusalem, 91120 Jerusalem, Israel Department of Pharmacology, School of Pharmacy-Faculty of Medicine, Hebrew University of Jerusalem, 91120 Jerusalem, Israel Haharuv 18, P.O. Box 184, Timrat, 23840, Israel Department of Pathology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel David R. Bloom Center for Pharmacy, Alex Grass Center for Drug Design and Synthesis of Novel Therapeutics, Hebrew University, Jerusalem, Israel AU - Vaisman, B. AU - Motiei, M. AU - Nyska, A. AU - Domb, A. J. DB - Scopus DO - 10.1002/jbm.a.32342 IS - 2 KW - Biocompatibility Biodegradable polymer Implant Injectable drug-delivery scaffold Poly(ester-anhydride) copolymer Ricinoleic acid-based polymer M3 - Article N1 - Cited By :23 Export Date: 10 November 2020 PY - 2010 SP - 419-431 ST - Biocompatibility and safety evaluation of a ricinoleic acid-based poly(ester-anhydride) copolymer after implantation in rats T2 - Journal of Biomedical Materials Research - Part A TI - Biocompatibility and safety evaluation of a ricinoleic acid-based poly(ester-anhydride) copolymer after implantation in rats UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-75149188602&doi=10.1002%2fjbm.a.32342&partnerID=40&md5=bedb9426c26faa2b75f472a18b82f256 VL - 92 ID - 1469 ER - TY - JOUR AB - The aim of this study was to decellularize a 30cm long segment of porcine small intestine, determine its in vivo behaviour and assess the type of immunological reaction it induces in a quantitative manner. A segment of porcine ileum up to 30cm long, together with its attached vasculature, was decellularized via its mesenteric arcade as a single entity. The quality of the acellular scaffold was assessed histologically and using molecular tools. The host response to the scaffold was evaluated in a rodent model. Stereological techniques were incorporated into quantitative analysis of the phenotype of the macrophages infiltrating the scaffold in vivo. Lengths of ileal scaffold, together with its attached vasculature, were successfully decellularized, with no evidence of intact cells and DNA or collagen and GAGs overdegradation. Analysis of explants harvested over 2months postimplantation revealed full-thickness recellularization and no signs of foreign body or immune reactions. Macrophage profiling proved that between weeks 4 and 8 in vivo there was a switch from an M1 (pro-inflammatory) to an M2 (pro-remodelling) type of response. We show here that the decellularization process results in a biocompatible and non-toxic matrix that upon implantation triggers cellular infiltration and angiogenesis, primarily characterized by a pro-remodelling type of mononuclear response, without inducing foreign body reaction or fibrosis. © 2016 John Wiley & Sons, Ltd. AD - Department of Surgical Research, NPIMR, Harrow, United Kingdom St Mark's Hospital, Harrow, United Kingdom AU - Nowocin, A. K. AU - Southgate, A. AU - Gabe, S. M. AU - Ansari, T. DB - Scopus DO - 10.1002/term.1750 IS - 1 KW - Bicompatibility Decellularization ECM scaffold Host response Macrophage responses Subcutaneous implantation Tissue remodelling M3 - Article N1 - Cited By :16 Export Date: 10 November 2020 PY - 2016 SP - E23-E33 ST - Biocompatibility and potential of decellularized porcine small intestine to support cellular attachment and growth T2 - Journal of Tissue Engineering and Regenerative Medicine TI - Biocompatibility and potential of decellularized porcine small intestine to support cellular attachment and growth UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84954370959&doi=10.1002%2fterm.1750&partnerID=40&md5=be0b233bfb2f1115de1c4bdf8c5f6668 VL - 10 ID - 1208 ER - TY - JOUR AB - Kafirin, the sorghum prolamin protein, like its maize homologue zein, can be made into microparticles and films and potentially used as a biomaterial. Zein has good bio- and cyto-compatibility. Kafirin could be advantageous as it is more hydrophobic, more crosslinked, more slowly digested by mammalian proteases than zein and is non-allergenic. The safety and biocompatibility of kafirin implants in two forms was determined in rodent models. One week post subcutaneous injection of kafirin microparticles (size 5-μm diameter) in mice, chronic inflammation, abnormal red blood cells, and gross fibrin formation were observed. This chronic inflammatory response was possibly caused by the release of hydrolysis products such as glutamate during the degradation of the kafirin microparticles. In contrast, films made from kafirin microparticles (50-μm thick, folded into 1 cm3) implanted in rats showed no abnormal inflammatory reactions and were only partially degraded by day 28. The slower degradation of the kafirin films was probably due to their far smaller surface area when compared to kafirin microparticles. Thus, kafirin films appear to have potential as a biomaterial. This study also raises awareness that the form of prolamin based biomaterials, (kafirin and zein) should be considered when assessing the safety of such materials. © 2014 Wiley Periodicals, Inc. AD - Institute for Food, Nutrition and Well-Being, Department of Food Science, University of Pretoria, Private Bag X20, Hatfield, 0028, South Africa Department of Dairy and Food Science and Technology, Egerton University, Nakuru, Kenya Department of Immunology, Institute for Cellular and Molecular Medicine, University of Pretoria, Pretoria, South Africa Biomedical Research Centre, Faculty of Veterinary Science, University of Pretoria, Pretoria, South Africa Department of Dairy and Food Science and Technology, Egerton University, Kenya AU - Taylor, J. AU - Anyango, J. O. AU - Potgieter, M. AU - Kallmeyer, K. AU - Naidoo, V. AU - Pepper, M. S. AU - Taylor, J. R. N. DB - Scopus DO - 10.1002/jbm.a.35394 IS - 8 KW - biocompatibility film histology kafirin microparticle M3 - Article N1 - Cited By :9 Export Date: 10 November 2020 PY - 2015 SP - 2582-2590 ST - Biocompatibility and biodegradation of protein microparticle and film scaffolds made from kafirin (sorghum prolamin protein) subcutaneously implanted in rodent models T2 - Journal of Biomedical Materials Research - Part A TI - Biocompatibility and biodegradation of protein microparticle and film scaffolds made from kafirin (sorghum prolamin protein) subcutaneously implanted in rodent models UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84933678037&doi=10.1002%2fjbm.a.35394&partnerID=40&md5=77c2e5d7f9234b29f20c120b8833fbc9 VL - 103 ID - 1224 ER - TY - JOUR AB - Chest-wall invading malignancies usually necessitate the resection of the respective part of the thoracic wall. Gore-Tex® is the material of choice that is traditionally used to repair thoracic defects. This material is well accepted by the recipient; however, though not rejected, it is an inert material and behaves like a 'foreign body' within the thoracic wall. By contrast, there are materials that have the potential to physiologically integrate into the host, and these materials are currently under in vitro and also in vivo investigation. These materials offer a gradual but complete biodegradation over time, and severe adverse inflammatory responses can be avoided. Here, we present a novel material that is a biodegradable nanocomposite based on poly-lactic-co-glycolic acid and amorphous calcium phosphate nanoparticles in comparison to the traditionally employed Gore-Tex® being the standard for chest-wall replacement. On a mouse model of thoracic wall resection, that resembles the technique and localization applied in humans, poly-lactic-co-glycolic acid and amorphous calcium phosphate nanoparticles and Gore-Tex® were implanted subcutaneously and additionally tested in a separate series as a chest-wall graft. After 1, 2, 4 and 8 weeks cell infiltration into the respective materials, inflammatory reactions as well as neo-vascularization (endothelial cells) were determined in six different zones. While Gore-Tex® allowed for cell infiltration only at the outer surface, electrospun poly-lactic-co-glycolic acid and amorphous calcium phosphate nanoparticles were completely penetrated by infiltrating cells. These cells were composed mainly by macrophages, with only 4% of giant cells and lymphocytes. Total macrophage count increased by time while the number of IL1-β-expressing macrophages decreased, indicating a protective state towards the graft. As such, poly-lactic-co-glycolic acid and amorphous calcium phosphate nanoparticles seem to develop ideal characteristics as a material for chest-wall replacement by (a) having the advantage of full biodegradation, (b) displaying stable chest-wall structures and (c) adapting a physiological and integrating graft compared to Gore-Tex®. AD - Division of Thoracic Surgery, University Hospital Zurich, Switzerland. Department of Chemistry and Applied Biosciences, Institute for Chemical and Bioengineering, ETH Zurich, Zurich, Switzerland. Division of Clinical Pathology, University Hospital Zurich, Switzerland. Division of Plastic and Hand Surgery, University Hospital Zurich, Switzerland johanna.buschmann@usz.ch. AN - 24293248 AU - Jungraithmayr, W. AU - Laube, I. AU - Hild, N. AU - Stark, W. J. AU - Mihic-Probst, D. AU - Weder, W. AU - Buschmann, J. DA - Jul DO - 10.1177/0885328213513621 DP - NLM ET - 2013/12/03 IS - 1 KW - Absorbable Implants Animals *Biocompatible Materials Calcium Phosphates Humans Lactic Acid Male Materials Testing Mice Mice, Inbred C57BL *Nanocomposites Neovascularization, Physiologic Polyglycolic Acid Polylactic Acid-Polyglycolic Acid Copolymer Polytetrafluoroethylene Thoracic Wall/metabolism/pathology/*surgery Tissue Scaffolds *Chest-wall replacement *Gore-Tex® *PLGA/a-CaP *amorphous calcium phosphate nanoparticle *degradation kinetics *electrospinning LA - eng N1 - 1530-8022 Jungraithmayr, Wolfgang Laube, Isabelle Hild, Nora Stark, Wendelin J Mihic-Probst, Daniela Weder, Walter Buschmann, Johanna Journal Article England J Biomater Appl. 2014 Jul;29(1):36-45. doi: 10.1177/0885328213513621. Epub 2013 Nov 28. PY - 2014 SN - 0885-3282 SP - 36-45 ST - Bioactive nanocomposite for chest-wall replacement: Cellular response in a murine model T2 - J Biomater Appl TI - Bioactive nanocomposite for chest-wall replacement: Cellular response in a murine model VL - 29 ID - 146 ER - TY - JOUR AB - Biliary fascioliasis is a rare infection of the hepatobiliary system. In human, it is known to present with two main phases; acute phase (hepatic phase) presenting with abdominal pain or abnormal liver biochemistry then chronic phase (biliary phase) presenting with biliary obstruction or cholangitis. Optimal treatment of biliary fascioliasis consists of endoscopic retrograde cholangiography with removal of the parasite and single oral dose of triclabendazole. We report a rare case of biliary fascioliasis in chronic calcified pancreatitis who presented with ascending cholangitis and biliary stricture. A 63-years-old Thai man was referred to our hospital for treatment of clinical symptoms severe cholangitis. Magnetic resonance cholangiopancreatography showed evidence of distal common bile duct stricture associated with chronic calcific pancreatitis. ERCP was performed, that found a few amorphous filling defects in the common bile duct and distal biliary stricture. After removal of the foreign body of what seems to be a fluke parasite followed with single oral dose triclabendazole thereafter, the clinical symptom was improved dramatically. © 2019 S. Karger AG. All rights reserved. AD - NKC Institute of Gastroenterology and Hepatology, Songklanagarind Hospital, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand Internal Medicine, Shanghai Medical College, Fudan University, Shanghai, China AU - Pattarapuntakul, T. AU - Ovartlarnporn, B. AU - Rojsanga, W. AU - Yungyoo, T. DB - Scopus DO - 10.1159/000503277 IS - 3 M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 438-444 ST - Biliary Fascioliasis in Chronic Calcific Pancreatitis Presenting with Ascending Cholangitis and Biliary Stricture T2 - Case Reports in Gastroenterology TI - Biliary Fascioliasis in Chronic Calcific Pancreatitis Presenting with Ascending Cholangitis and Biliary Stricture UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85073606676&doi=10.1159%2f000503277&partnerID=40&md5=10855d8179f72c464deba0331bec265d VL - 13 ID - 1039 ER - TY - JOUR AB - We report a rare case of bile duct stone formation around an ingested fish bone as a nidus after pancreatoduodenectomy. A 78-year-old woman was admitted to our department for fever and epigastric pain. Abdominal computed tomography revealed an elongated bile duct stone containing a linearly shaped foreign body of bone density. Enteroscopic lithotomy was performed using single balloon enteroscopy to safely remove the stone and foreign body from the bile duct. The foreign body was determined to be a fish bone by pathological examination and component analysis. © 2018 The Author(s). Published by S. Karger AG, Basel. AD - Gastroenterology Division, Japanese Red Cross Society Kyoto Daiichi Hospital, 15-749 Honmachi, Higashiyama-ku, Kyoto City, Kyoto, 605-0981, Japan AU - Sakakida, T. AU - Sato, H. AU - Doi, T. AU - Kawakami, T. AU - Nakatsugawa, Y. AU - Nishimura, K. AU - Yamada, S. AU - Fujii, H. AU - Tomatsuri, N. AU - Okuyama, Y. AU - Kimura, H. AU - Yoshida, N. DB - Scopus DO - 10.1159/000486191 IS - 1 KW - Bile duct stone Fish bone Foreign body Pancreatoduodenectomy M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2018 SP - 69-75 ST - A Bile Duct Stone Formation around a Fish Bone as a Nidus after Pancreatoduodenectomy T2 - Case Reports in Gastroenterology TI - A Bile Duct Stone Formation around a Fish Bone as a Nidus after Pancreatoduodenectomy UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85042110826&doi=10.1159%2f000486191&partnerID=40&md5=4df86da956c4732172498df17a45be01 VL - 12 ID - 1080 ER - TY - JOUR AN - 105413870. Language: English. Entry Date: 20091002. Revision Date: 20150711. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 2 KW - Retained Instruments -- Prevention and Control Risk Management -- Methods Surgical Count Procedure -- Methods Bar Coding Communication Barriers Distraction Human Error Incident Reports -- Pennsylvania Pennsylvania Personnel Turnover Practice Guidelines Retained Instruments -- Risk Factors N1 - questionnaire/scale; review. Journal Subset: Health Promotion/Education; USA. PY - 2009 SN - 1941-7144 SP - 39-45 ST - Beyond the count: preventing the retention of foreign objects T2 - Pennsylvania Patient Safety Advisory TI - Beyond the count: preventing the retention of foreign objects UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105413870&site=ehost-live&scope=site VL - 6 ID - 909 ER - TY - JOUR AB - Background: Surgical staplers currently all rely on the same staple form—the “B” which necessitates a high delivery profile (12 mm). A novel “D” shape staple allows for an extremely low profile of the applicator. The acute and long-term efficacy of a D-shaped staple (Cardica, Redwood City, CA, USA) was compared to conventional B-form staples (Covidien, Norwalk, CN, USA) in an animal model for intestinal transections and anastomoses. Methods: Jejunojejunal anastomoses (JJ) were performed via mini-laparotomy in a swine model. White & blue D- and B-shaped staples were studied in three groups (planned survival 14–84 days). Intraoperative assessment included completeness of staple line, hemostasis, and need for intervention. Postoperatively, animals were evaluated for complications. At the time of sacrifice, gross pathological and histological assessments were performed. Results: Twenty-three animals had 40 anastomoses (23 “D” and 17 “B” staple anastomoses) with no intraoperative mortalities. One “D” staple application required a manual extension of the cut. Acute hemostasis was 100 %. Group 1 (n = 5) compared white staples in JJs (D staple n = 5; B staple n = 5; 14-day survival = 100 %). Group 2 (n = 12) compared white staples in JJs (D staple n = 12; B staple n = 6; 34-day survival = 92 %). One animal died on day 4 for a non-staple related cause. Group 3 (n = 6) compared blue staples in JJs (D staple n = 6; B staple n = 6; 84 day survival = 84 %). One animal died on day 18 due to an obstruction at the B staple JJ caused by stricture. There were no other bleeding, leaks or strictures in any of the groups. Gross pathology and histology were unremarkable in all JJs. Conclusions: This study showed no difference in intraoperative performance and the chronic healing response in JJs between D- and B-shaped staples. Based on these findings, the D-shaped staple elicits a normal healing response in jejunostomies and offers the possibility of clinical use of this advance in staple design. © 2015, The Author(s). AD - Cardiocentro Ticino & University of Bern, Lugano, Switzerland Experimental Surgery Institute, University of Bern, Bern, Switzerland VDx Veterinary Diagnostics, Davis, CA, United States Cardica Inc, Redwood City, CA, United States The Oregon Clinic, Portland, OR, United States AU - Demertzis, S. AU - Beslac, O. AU - Mettler, D. AU - Zalokar, D. AU - Spangler, T. AU - Hausen, B. AU - Swanstrom, L. DB - Scopus DO - 10.1007/s00464-015-4125-x IS - 12 KW - Anastomosis Laparoscopy Staples Surgical staplers M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2015 SP - 3674-3684 ST - Beyond the “B”: a new concept of the surgical staple enabling miniature staplers T2 - Surgical Endoscopy TI - Beyond the “B”: a new concept of the surgical staple enabling miniature staplers UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84947485256&doi=10.1007%2fs00464-015-4125-x&partnerID=40&md5=e8864f5cc14f8ae97ebb4114da5a5a1c VL - 29 ID - 1213 ER - TY - JOUR AN - 18156917 AU - Greenberg, C. C. AU - Gawande, A. A. DA - Jan DO - 10.1097/SLA.0b013e318160c194 DP - NLM ET - 2007/12/25 IS - 1 KW - Foreign Bodies/*diagnostic imaging/*prevention & control Humans Medical Errors/*prevention & control Needles Operating Rooms Radiography Sensitivity and Specificity *Surgical Instruments LA - eng N1 - Greenberg, Caprice C Gawande, Atul A Comment Editorial United States Ann Surg. 2008 Jan;247(1):19-20. doi: 10.1097/SLA.0b013e318160c194. PY - 2008 SN - 0003-4932 (Print) 0003-4932 SP - 19-20 ST - Beyond counting: current evidence on the problem of retaining foreign bodies in surgery? T2 - Ann Surg TI - Beyond counting: current evidence on the problem of retaining foreign bodies in surgery? VL - 247 ID - 73 ER - TY - JOUR AD - P. Cole, Houston, TX, United States AU - Cole, P. AU - Hollier, L. DB - Embase DO - 10.1097/SCS.0b013e31816ae491 IS - 3 KW - clinical practice foreign body morbidity needle note priority journal surgery surgical equipment LA - English M3 - Note N1 - L351786521 2008-07-18 PY - 2008 SN - 1049-2275 SP - 833 ST - Beyond counting: Current evidence on the problem of retaining foreign bodies in surgery? T2 - Journal of Craniofacial Surgery TI - Beyond counting: Current evidence on the problem of retaining foreign bodies in surgery? UR - https://www.embase.com/search/results?subaction=viewrecord&id=L351786521&from=export http://dx.doi.org/10.1097/SCS.0b013e31816ae491 VL - 19 ID - 599 ER - TY - JOUR AB - Introduction: Rectal foreign bodies often cause a serious challenge on the clinician. Objects can be inserted for diagnostic or therapeutic purposes, or self-treatment of anorectal disease, by criminal assault and accident but most commonly, for sexual purposes. We aimed to evaluate patients with foreign bodies in rectum and review the management strategy of these patients in this paper. Materials and methods: The data of all the patients who were treated in Tepecik Education and Research Hospital and Atatürk Education and Research Hospital, General Surgery Departments during a 7 years period between 2006 and 2013 were retrospectively analysed. Results: A total of 36 patients, 33 men and 3 women, were admitted with retained rectal foreign body or associated complications. The age range was from 14 to 71 years. The time to presentation and extraction of the foreign body is a range of 4 hours to 15 days. 8 of 36 patients underwent surgery. Discussion: Colorectal foreign bodies are usually inserted for sexual activity. Physical and rectal examination, rectosigmoidoscopy and plain radiograms should be routinezed for diagnosis and localisation. The first principle in treatment is simplicity. At least 24 hours of observation while eliminating perforation with repeated physical examinations and plain abdominal x rays is necessary for cases whom the extraction of the object achieved via anus. AD - Tepecik Education and Research Hospital, Department of General Surgery, 35040 Yenişehir, Izmir, Turkey Atatürk Education and Research Hospital, Department of General Surgery, 35360 Basin Sitesi Izmir, Turkey AU - Ünver, M. AU - Öztürk, S. AU - Ölmez, M. AU - Kumkumoǧlu, Y. AU - Zalluhoǧlu, N. AU - Bozbiyik, O. AU - Kebapçi, E. AU - Erol, V. AU - Doǧan, S. M. AU - Uǧurlu, L. AU - Turgut, E. AU - Karaca, C. AU - Haciyanli, M. AU - Aydin, C. AU - Akbulut, G. DB - Scopus IS - 3 KW - Colorectal Foreign body Simplicity M3 - Article N1 - Export Date: 10 November 2020 PY - 2014 SP - 737-741 ST - The best treatment option in colorectal foreign bodies; simplicity: Experience of two centers T2 - Acta Medica Mediterranea TI - The best treatment option in colorectal foreign bodies; simplicity: Experience of two centers UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84902991755&partnerID=40&md5=e56cb892db678aab33f6406ac907a0b7 VL - 30 ID - 1272 ER - TY - JOUR AN - 106360290. Language: English. Entry Date: 20081121. Revision Date: 20200708. Publication Type: Journal Article DB - ccm DO - 10.1016/S0001-2092(06)60083-5 DP - EBSCOhost KW - Patient Safety Retained Instruments -- Prevention and Control Surgical Count Procedure AORN Education, Continuing (Credit) Perioperative Nursing Surgical Count Procedure -- Standards Surgical Sponges N1 - case study; CEU; exam questions. Supplement Title: Jul2006 Supplement. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 0372403. PMID: NLM16892940. PY - 2006 SN - 0001-2092 SP - S30-60 ST - Best practices for preventing a retained foreign body T2 - AORN Journal TI - Best practices for preventing a retained foreign body UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106360290&site=ehost-live&scope=site VL - 84 ID - 871 ER - TY - JOUR AB - The article reports on best practices, including counting all medical items used in surgery, careful observation of the packaging of medical devices used in surgery and careful separation of all counted surgical items, which can be used by health care facilities to avoid foreign object retainment following surgery. AD - Partner Kaufman Borgeest & Ryan New York, NY Associate Kaufman Borgeest & Ryan New York, NY Director of Risk and Claims Management The New York Hospital Medical Center of Queens Flushing, NY AN - 76912515. Language: English. Entry Date: 20121016. Revision Date: 20190620. Publication Type: Article. Journal Subset: Biomedical AU - Rubin, Jonathan D. AU - Brown, Sandra L. AU - Safran, Alvin DB - ccm DP - EBSCOhost IS - 7 KW - Retained Instruments -- Prevention and Control Surgical Count Procedure -- Standards Operating Rooms -- Administration Surgical Sponges Operating Room Personnel N1 - Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2012 SN - 0190-5066 SP - 75-76 ST - Best practices avoid retained sponges T2 - Same-Day Surgery TI - Best practices avoid retained sponges UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=76912515&site=ehost-live&scope=site VL - 36 ID - 827 ER - TY - JOUR AB - INTRODUCTION: The occurrence of cyst around total hip arthroplasty (THA) is rare. There are several well-described causes of mass following THA, including polyethylene and metal wear debris, infection, expanding hematoma, and synovial cysts. However, formation of benign xanthogranulomatous cyst of the hip following THR has never been reported before, to the best of our knowledge. CASE REPORT: We report a case of a 68-year-old gentleman, with underlying end stage renal failure, had bilateral THA done 10 years ago. He presented with progressively increasing size of painless right hip swelling for one-year duration. He had no fever or constitutional symptom. The mass sized 15 × 8cm over the anterolateral aspect of the hip joint. It was fluctuant with smooth surface. There was an ulcer discharging clear yellowish fluid over the mass. Plain radiograph showed increased soft tissue shadow over the lateral aspect of the right hip and proximal femur (figure 1). No periprosthetic radiolucency to suggest loosening or osteolysis. ESR and CRP were raised, while total white count within the normal range. With suspicion of infection, patient was planned for debridement surgery. Intra-operative finding was a large cyst which contained about 1.5 liter of clear fluid, lower viscosity in comparison with synovial fluid. The cyst wall enveloped the hip joint from anterior to posterior, connecting with lining of the acetabulum. Posteriorly, the cyst wall covered the gluteus maximus muscle and overlying the sciatic nerve. Laterally, the cyst wall extended and wrapped the proximal femur almost 80 percent of the circumferential perimeter (figure 2). The cyst wall was excised. The prosthesis was found to be stable. Patient was covered with short term antibiotic. One-year post surgery, patient was asymptomatic and no implant loosening to date. (Figure Parsented) Histopathological examination of the cyst showed two different morphologies. One is massive collection of foamy macrophages, foreign body giant cells surrounding by numerous cholesterol cleft which occupies the entire dermis up to subcutis with chronic inflammatory cells where eosinophils seen throughout the lesion and thickened fibrous wall This represents the xanthogranulomatous changes secondary to lipid base foreign body. DISCUSSIONS: It was thought that wear debris may function as a foreign body and phagocytosed by macrophages, resulting in a granulomatous reaction. These cysts also believed to be subclinical infections which currently known as granulomatous pseudotumours. However, in our case, we didn't observe any implant loosening. Microscopic wear from the polyethylene is a possible cause. CONCLUSION: Benign xanthogranulomatous cyst around the THA in this case did not associate with visible prosthesis problem, and was treated with excision and short term antibiotic. This is a rare clinical scenario, and long term follow up of the patient will better show the natural history of the disease. AD - Y. Sahran, Orthopaedic Department, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia AU - Sahran, Y. AU - Nadiah, N. H. AU - Din, M. H. AU - Faisham, W. I. AU - Othman, H. AU - Najmiyah, W. A. B. DB - Embase KW - antibiotic agent cholesterol polyethylene acetabulum aged asymptomatic infection case report clinical article conference abstract cyst debridement dermis end stage renal disease eosinophil fever follow up giant cell gluteus maximus muscle granulomatous inflammation histopathology history human human cell infection inflammatory cell macrophage male osteolysis perimeter proximal femur pseudotumor sciatic nerve soft tissue subcutaneous tissue surgery surgical patient swelling synovial fluid thinking total hip prosthesis ulcer viscosity X ray film LA - English M3 - Conference Abstract N1 - L623051657 2018-07-20 PY - 2017 SN - 1985-2533 ST - Benign xanthogranulomatous cyst of the hip following total hip arthroplasty: A case report T2 - Malaysian Orthopaedic Journal TI - Benign xanthogranulomatous cyst of the hip following total hip arthroplasty: A case report UR - https://www.embase.com/search/results?subaction=viewrecord&id=L623051657&from=export VL - 11 ID - 385 ER - TY - JOUR AB - Objective. Before peripheral nerve electrodes can be used for the restoration of sensory and motor functions in patients with neurological disorders, the behavioral and histological consequences of these devices must be investigated. These indices of biocompatibility can be defined in terms of desired functional outcomes; for example, a device may be considered for use as a therapeutic intervention if the implanted subject retains functional neurons post-implantation even in the presence of a foreign body response. The consequences of an indwelling device may remain localized to cellular responses at the device-tissue interface, such as fibrotic encapsulation of the device, or they may affect the animal more globally, such as impacting behavioral or sensorimotor functions. The objective of this study was to investigate the overall consequences of implantation of high-electrode count intrafascicular peripheral nerve arrays, High Density Utah Slanted Electrode Arrays (HD-USEAs; 25 electrodes mm-2). Approach. HD-USEAs were implanted in rat sciatic nerves for one and two month periods. We monitored wheel running, noxious sensory paw withdrawal reflexes, footprints, nerve morphology and macrophage presence at the tissue-device interface. In addition, we used a novel approach to contain the arrays in actively behaving animals that consisted of an organic nerve wrap. A total of 500 electrodes were implanted across all ten animals. Main results. The results demonstrated that chronic implantation (≤8 weeks) of HD-USEAs into peripheral nerves can evoke behavioral deficits that recover over time. Morphology of the nerve distal to the implantation site showed variable signs of nerve fiber degeneration and regeneration. Cytology adjacent to the device-tissue interface also showed a variable response, with some electrodes having many macrophages surrounding the electrodes, while other electrodes had few or no macrophages present. This variability was also seen along the length of the electrodes. Axons remained within the proximity of the electrode tips at the distances required for theoretically effective stimulation and recording (≤100 μm). Significance. We conclude from these studies that HD-USEAs do not cause overall global effects on the animals, at least up to the two-month period investigated here. These results demonstrate for the first time that the consequences of high-electrode count intrafascicular arrays compare with other peripheral nerve electrodes currently available for clinical or investigational neuromodulation. © 2014 IOP Publishing Ltd. AD - Department of Bioengineering, University of Utah, Salt Lake City, UT, United States Biomedical Engineering Research Group, CIBER BBN, Universidad de Miguel Hernández, Elche, Alicante, Spain AU - Wark, H. A. C. AU - Mathews, K. S. AU - Normann, R. A. AU - Fernandez, E. C7 - 046027 DB - Scopus DO - 10.1088/1741-2560/11/4/046027 IS - 4 KW - biocompatibility microelectrodes nerve electrodes neural prosthesis peripheral nerve M3 - Article N1 - Cited By :28 Export Date: 10 November 2020 PY - 2014 ST - Behavioral and cellular consequences of high-electrode count Utah Arrays chronically implanted in rat sciatic nerve T2 - Journal of Neural Engineering TI - Behavioral and cellular consequences of high-electrode count Utah Arrays chronically implanted in rat sciatic nerve UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84904630301&doi=10.1088%2f1741-2560%2f11%2f4%2f046027&partnerID=40&md5=5108cf3a1301c837481f9934f23bec07 VL - 11 ID - 1258 ER - TY - JOUR AB - The main aim of this work was to study the usefulness of human β-defensins 2 (BD-2) and 3 (BD-3), which are part of the innate immune system, in the treatment of infected ischemic skin flaps. We investigated the effect of transducing rat ischemic skin flaps with lentiviral vectors encoding human BD-2, BD-3, or both BD-2 and BD-3, to increase flap survival in the context of a P. aeruginosa infection associated with a foreign body. The secondary endpoints assessed were: bacterial counts, and biofilm formation on the surface of the foreign body. A local ischemic environment was created by producing arterialized venous flaps in the left epigastric region of rats. Flaps were intentionally infected by placing underneath them two catheters with 10(5) CFU of P. aeruginosa before the surgical wounds were hermetically closed. Flap biopsies were performed 3 and 7 days post-operatively, and the specimens submitted to immunohistochemical analysis for BD-2 and BD-3, as well as to bacterial quantification. Subsequently, the catheter segments were analyzed with scanning electron microscopy (SEM). Flaps transduced with BD-2 and BD-3 showed expression of these defensins and presented increased flap survival. Rats transduced with BD-3 presented a net reduction in the number of P. aeruginosa on the surface of the foreign body and lesser biofilm formation. AD - Anatomy Department, NOVA Medical School, Universidade NOVA de Lisboa, Lisbon, Portugal. diogo_bogalhao@yahoo.co.uk. Plastic and Reconstructive Surgery Department and Burn Unit, Centro Hospitalar de Lisboa Central - Hospital de São José, Lisbon, Portugal. diogo_bogalhao@yahoo.co.uk. UCIBIO, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, Lisbon, Caparica, Portugal. diogo_bogalhao@yahoo.co.uk. CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Lisbon, Portugal. diogo_bogalhao@yahoo.co.uk. UCIBIO, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, Lisbon, Caparica, Portugal. CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Lisbon, Portugal. Molecular Microbiology and Biotechnology Unit, iMed, ULisboa, Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal. INESC MN - Microsystems and Nanotechnologies, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal. Pathology Department, Centro Hospitalar de Lisboa Central - Hospital de São José, Lisbon, Portugal. LIBPhys, Physics Department, Faculdade de Ciências e Tecnologias, Universidade NOVA de Lisboa, Lisbon, Caparica, Portugal. Anatomy Department, NOVA Medical School, Universidade NOVA de Lisboa, Lisbon, Portugal. UCIBIO, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, Lisbon, Caparica, Portugal. p.videira@fct.unl.pt. CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Lisbon, Portugal. p.videira@fct.unl.pt. CDG & Allies- Professional and Patient Association International Network (PPAIN), Lisbon, Caparica, Portugal. p.videira@fct.unl.pt. AN - 31133641 AU - Casal, D. AU - Iria, I. AU - Ramalho, J. S. AU - Alves, S. AU - Mota-Silva, E. AU - Mascarenhas-Lemos, L. AU - Pontinha, C. AU - Guadalupe-Cabral, M. AU - Ferreira-Silva, J. AU - Ferraz-Oliveira, M. AU - Vassilenko, V. AU - Goyri-O'Neill, J. AU - Pais, D. AU - Videira, P. A. C2 - PMC6536547 DA - May 27 DO - 10.1038/s41598-019-44153-y DP - NLM ET - 2019/05/28 IS - 1 KW - Animals Anti-Bacterial Agents/metabolism/therapeutic use Disease Models, Animal Genetic Therapy Genetic Vectors/genetics/*therapeutic use Graft Survival Humans Ischemia/*complications Male Pseudomonas Infections/*complications/*therapy Pseudomonas aeruginosa/drug effects Rats Rats, Wistar Skin Transplantation/adverse effects Surgical Flaps/adverse effects/*microbiology Transduction, Genetic beta-Defensins/genetics/*therapeutic use LA - eng N1 - 2045-2322 Casal, Diogo Orcid: 0000-0002-5537-9340 Iria, Inês Ramalho, José S Alves, Sara Mota-Silva, Eduarda Mascarenhas-Lemos, Luís Pontinha, Carlos Orcid: 0000-0002-1265-949x Guadalupe-Cabral, Maria Ferreira-Silva, José Ferraz-Oliveira, Mário Vassilenko, Valentina Orcid: 0000-0002-7913-7047 Goyri-O'Neill, João Pais, Diogo Videira, Paula A Orcid: 0000-0001-5987-2485 Journal Article Sci Rep. 2019 May 27;9(1):7854. doi: 10.1038/s41598-019-44153-y. PY - 2019 SN - 2045-2322 SP - 7854 ST - BD-2 and BD-3 increase skin flap survival in a model of ischemia and Pseudomonas aeruginosa infection T2 - Sci Rep TI - BD-2 and BD-3 increase skin flap survival in a model of ischemia and Pseudomonas aeruginosa infection VL - 9 ID - 231 ER - TY - JOUR AB - OBJECTIVE: A randomized, controlled trial was performed to evaluate a computer-assisted method for counting sponges using a bar-code system. BACKGROUND: Retained sponges are a rare and preventable problem but persist in surgery despite standardized protocols for counting. Technology that improves detection of counting errors could reduce risk to surgical patients. METHODS: We performed a randomized controlled trial comparing a bar-coded sponge system with a traditional counting protocol in 300 general surgery operations. Observers monitored sponge and instrument counts and recorded all incidents of miscounted or misplaced sponges. Surgeons and operating room staff completed postoperative and end-of-study surveys evaluating the bar-code system. RESULTS: The bar-code system detected significantly more counting discrepancies than the traditional protocol (32 vs.13 discrepancies, P = 0.007). These discrepancies involved both misplaced sponges (21 vs. 12 sponges, P = 0.17) and miscounted sponges (11 vs. 1 sponge, P = 0.007). The system introduced new technical difficulties (2.04 per 1000 sponges) and increased the time spent counting sponges (5.3 vs. 2.4 minutes, P < 0.0001). In postoperative surveys, there was no difference in surgical teams' confidence that all sponges were accounted for, but they rated the counting process and team performance lower in operations randomized to the bar-code arm. By the end of the study, however, most providers found the system easy to use, felt confident in its ability to track sponges, and reported a positive effect on the counting process. CONCLUSIONS: Use of automated counting using bar-coded surgical sponges improved detection of miscounted and misplaced sponges and was well tolerated by surgical staff members. AD - Center for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA 02115, USA. AN - 18362623 AU - Greenberg, C. C. AU - Diaz-Flores, R. AU - Lipsitz, S. R. AU - Regenbogen, S. E. AU - Mulholland, L. AU - Mearn, F. AU - Rao, S. AU - Toidze, T. AU - Gawande, A. A. DA - Apr DO - 10.1097/SLA.0b013e3181656cd5 DP - NLM ET - 2008/03/26 IS - 4 KW - *Electronic Data Processing Female Foreign Bodies/*prevention & control Humans Male Medical Errors/*prevention & control Middle Aged Safety *Surgical Sponges/adverse effects/statistics & numerical data LA - eng N1 - Greenberg, Caprice C Diaz-Flores, Rafael Lipsitz, Stuart R Regenbogen, Scott E Mulholland, Lynn Mearn, Francine Rao, Shilpa Toidze, Tamara Gawande, Atul A Comparative Study Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't United States Ann Surg. 2008 Apr;247(4):612-6. doi: 10.1097/SLA.0b013e3181656cd5. PY - 2008 SN - 0003-4932 (Print) 0003-4932 SP - 612-6 ST - Bar-coding surgical sponges to improve safety: a randomized controlled trial T2 - Ann Surg TI - Bar-coding surgical sponges to improve safety: a randomized controlled trial VL - 247 ID - 77 ER - TY - JOUR AD - Department of Internal Medicine (Gastroenterology), Hiroshima Kyoritsu Hospital, Hiroshima City, Japan AU - Toh Yoon, E. W. AU - Nishihara, K. DB - Scopus DO - 10.1016/j.cgh.2017.01.003 IS - 8 M3 - Article N1 - Export Date: 10 November 2020 PY - 2017 SP - e133-e134 ST - Ball Valve Syndrome Caused by the Migration of Gastrostomy Catheter Tip T2 - Clinical Gastroenterology and Hepatology TI - Ball Valve Syndrome Caused by the Migration of Gastrostomy Catheter Tip UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019046464&doi=10.1016%2fj.cgh.2017.01.003&partnerID=40&md5=25556a8e2a91c372583116ccdceb7222 VL - 15 ID - 1126 ER - TY - JOUR AB - Purpose: To report a case of bacterial endophthalmitis associated with a retained smallgauge vitrectomy trocar. Methods: Retrospective case report of a 66-year-old woman who underwent 25-gauge vitrectomy surgery for an epiretinal membrane who presented with postoperative bacterial endophthalmitis and hand motions vision 3 weeks later. Results: Aqueous and vitreous biopsy revealed Corynebacterium species sensitive to vancomycin. The patient was initially treated with intravitreal and subconjunctival injections of vancomycin, ceftazidime, and dexamethasone. Surgical exploration during a subsequent vitrectomy surgery revealed a retained, transscleral 25-gauge cannula beneath a subconjunctival abscess. The cannula was removed, and the patient was treated with vitrectomy, debridement and closure of the transscleral wound, and injection of intravitreal antibiotics. Fifteen months of follow-up revealed no recurrence of infection and improvement of vision to 20/150. Conclusion: Although rare, retained small-gauge vitrectomy cannulas may lead to vision threatening ocular infection. Care should be taken to inspect both the wound and the removed trocar system to ensure complete removal of this surgical device. Detailed counts of all surgical equipment should be routinely performed at the conclusion of vitrectomy surgery. © 2015 by Ophthalmic Communications Society, Inc. AD - R.W. Wong, Austin Retina Assoc., 801 West 38th Street, Austin, TX, United States AU - Wong, R. W. DB - Embase Medline DO - 10.1097/ICB.0000000000000153 IS - 3 KW - cannula trocar vitrectomy cannula ceftazidime dexamethasone vancomycin abscess aged article bacterial endophthalmitis bacterium detection case report Corynebacterium debridement device removal diabetic retinopathy endophthalmitis epiretinal membrane eye examination female foreign body human human tissue laser coagulation nonhuman retrospective study visual acuity vitrectomy vitreous biopsy LA - English M3 - Article N1 - L604749484 2015-06-11 2015-06-16 PY - 2015 SN - 1937-1578 1935-1089 SP - 256-258 ST - Bacterial endophthalmitis associated with a broken and retained small-gauge vitrectomy cannula T2 - Retinal Cases and Brief Reports TI - Bacterial endophthalmitis associated with a broken and retained small-gauge vitrectomy cannula UR - https://www.embase.com/search/results?subaction=viewrecord&id=L604749484&from=export http://dx.doi.org/10.1097/ICB.0000000000000153 VL - 9 ID - 428 ER - TY - JOUR AB - BACKGROUND: Electrophysiological cardiac devices are increasingly used. The frequency of subclinical infection is unknown. We investigated all explanted devices using sonication, a method for detection of microbial biofilms on foreign bodies. METHODS AND RESULTS: Consecutive patients in whom cardiac pacemakers and implantable cardioverter/defibrillators were removed at our institution between October 2007 and December 2008 were prospectively included. Devices (generator and/or leads) were aseptically removed and sonicated, and the resulting sonication fluid was cultured. In parallel, conventional swabs of the generator pouch were performed. A total of 121 removed devices (68 pacemakers, 53 implantable cardioverter/defibrillators) were included. The reasons for removal were insufficient battery charge (n=102), device upgrading (n=9), device dysfunction (n=4), or infection (n=6). In 115 episodes (95%) without clinical evidence of infection, 44 (38%) grew bacteria in sonication fluid, including Propionibacterium acnes (n=27), coagulase-negative staphylococci (n=11), Gram-positive anaerobe cocci (n=3), Gram-positive anaerobe rods (n=1), Gram-negative rods (n=1), and mixed bacteria (n=1). In 21 of 44 sonication-positive episodes, bacterial counts were significant (>or=10 colony-forming units/mL of sonication fluid). In 26 sterilized controls, sonication cultures remained negative in 25 cases (96%). In 112 cases without clinical infection, conventional swab cultures were performed: 30 cultures (27%) were positive, and 18 (60%) were concordant with sonication fluid cultures. Six devices and leads were removed because of infection, growing Staphylococcus aureus, Streptococcus mitis, and coagulase-negative staphylococci in 6 sonication fluid cultures and 4 conventional swab cultures. CONCLUSIONS: Bacteria can colonize cardiac electrophysiological devices without clinical signs of infection. AD - Department of Internal Medicine, Luzerner Kantonsspital, Luzern. martin.rohacek@gmail.com AN - 20368521 AU - Rohacek, M. AU - Weisser, M. AU - Kobza, R. AU - Schoenenberger, A. W. AU - Pfyffer, G. E. AU - Frei, R. AU - Erne, P. AU - Trampuz, A. DA - Apr 20 DO - 10.1161/circulationaha.109.906461 DP - NLM ET - 2010/04/07 IS - 15 KW - Adult Aged Aged, 80 and over *Biofilms Defibrillators, Implantable/adverse effects/*microbiology Female Follow-Up Studies Gram-Negative Bacteria/isolation & purification Gram-Negative Bacterial Infections/diagnosis/microbiology Gram-Positive Bacteria/isolation & purification Gram-Positive Bacterial Infections/diagnosis/microbiology Humans Male Microbiological Techniques Middle Aged Pacemaker, Artificial/adverse effects/*microbiology Prospective Studies Prosthesis-Related Infections/*diagnosis/*microbiology Sonication LA - eng N1 - 1524-4539 Rohacek, Martin Weisser, Maja Kobza, Richard Schoenenberger, Andreas W Pfyffer, Gaby E Frei, Reno Erne, Paul Trampuz, Andrej Journal Article United States Circulation. 2010 Apr 20;121(15):1691-7. doi: 10.1161/CIRCULATIONAHA.109.906461. Epub 2010 Apr 5. PY - 2010 SN - 0009-7322 SP - 1691-7 ST - Bacterial colonization and infection of electrophysiological cardiac devices detected with sonication and swab culture T2 - Circulation TI - Bacterial colonization and infection of electrophysiological cardiac devices detected with sonication and swab culture VL - 121 ID - 98 ER - TY - JOUR AB - Retained surgical items (RSIs) pose serious consequences for patients and are a significant threat to patient safety. Perioperative team members are morally and ethically responsible for the prevention of RSIs and should understand how to reduce the risk of occurrence. The prevention of RSIs does not rest in the hands of one individual. It is a multidisciplinary endeavor that aims to reduce the risk of RSIs, and team members should hold each other accountable. This Back to Basics article focuses on the process of counting soft surgical goods, which are the most common RSIs. AN - 26924368 AU - Spruce, L. DA - Mar DO - 10.1016/j.aorn.2015.12.021 DP - NLM ET - 2016/03/01 IS - 3 KW - Education, Continuing Foreign Bodies/*prevention & control Humans Medical Errors/*prevention & control Operating Rooms Patient Safety Societies, Nursing *Surgical Sponges Workforce counting retained surgical items surgical sponge LA - eng N1 - 1878-0369 Spruce, Lisa Journal Article United States AORN J. 2016 Mar;103(3):298-301; quiz 302-3. doi: 10.1016/j.aorn.2015.12.021. PY - 2016 SN - 0001-2092 SP - 298-301; quiz 302-3 ST - Back to Basics: Counting Soft Surgical Goods T2 - Aorn j TI - Back to Basics: Counting Soft Surgical Goods VL - 103 ID - 172 ER - TY - JOUR AN - 108094611. Language: English. Entry Date: 20130315. Revision Date: 20200706. Publication Type: Journal Article AU - Jun, Kyung AU - Blaha, Jennifer DB - ccm DO - 10.1097/01.orn.0000421979.59820.a1 DP - EBSCOhost IS - 6 KW - Perioperative Nursing Retained Instruments -- Prevention and Control Surgical Count Procedure Accountability Insurance, Health, Reimbursement Intraoperative Care Questionnaires N1 - pictorial; questionnaire/scale. Journal Subset: Double Blind Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Perioperative Care. Instrumentation: Or Survey: Retained Foreign Objects. NLM UID: 101308226. PY - 2012 SN - 1933-3145 SP - 34-40 ST - Avoiding retained foreign objects T2 - OR Nurse TI - Avoiding retained foreign objects UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108094611&site=ehost-live&scope=site VL - 6 ID - 837 ER - TY - JOUR AB - BACKGROUND AND OBJECTIVE: Inadvertent retained surgical gauzes are an infrequent medical error but can have devastating consequences in the patient health and in the surgeon professional reputation. This problem seems easily preventable implementing standardized protocols for counting but due to human errors it still persists in surgery. The omnipresence of gauzes, their small size, and their similar appearance with tissues when they are soaked in blood make this error eradication really complex. In order to reduce the risk of accidental retention of surgical sponges in laparoscopy operations, in this paper we present an image processing system that tracks the gauzes on the video captured by the endoscope. METHODS: The proposed image processing application detects the presence of gauzes in the video images using texture analysis techniques. The process starts dividing the video frames into square blocks and each of these blocks is analyzed to determine whether it is similar to the gauze pattern. The video processing algorithm has been tested in a laparoscopic simulator under different conditions: with clean, slightly stained and soaked in blood gauzes as well as against different biological background tissues. Several methods, including different Local Binary Patterns (LBP) techniques and a convolutional neural network (CNN), have been analyzed in order to achieve a reliable detection in real time. RESULTS: The proposed LBP algorithm classifies the individual blocks in the image with 98% precision and 94% sensitivity which is sufficient to make a robust detection of any gauze that appears in the endoscopic video even if it is stained or soaked in blood. The results provided by the CNN are superior with 100% precision and 97% sensitivity, but due to the high computational demand, real-time video processing is not attainable in this case with standard hardware. CONCLUSIONS: The algorithm presented in this paper is a valuable tool to avoid the retention of surgical gauzes not only because of its reliability but also because it processes the video transparently and unattended, without the need for additional manipulation of special equipment in the operating room. AD - ITAP (Instituto de Tecnologías Avanzadas de la Producción), University of Valladolid, School of Industrial Engineering, Paseo del Cauce, 59, 47011 Valladolid, Spain. Electronic address: efuente@eii.uva.es. ITAP (Instituto de Tecnologías Avanzadas de la Producción), University of Valladolid, School of Industrial Engineering, Paseo del Cauce, 59, 47011 Valladolid, Spain. Electronic address: alvaro.munoz.garcia@alumnos.uva.es. ITAP (Instituto de Tecnologías Avanzadas de la Producción), University of Valladolid, School of Industrial Engineering, Paseo del Cauce, 59, 47011 Valladolid, Spain. Electronic address: lidia.santos@uva.es. ITAP (Instituto de Tecnologías Avanzadas de la Producción), University of Valladolid, School of Industrial Engineering, Paseo del Cauce, 59, 47011 Valladolid, Spain. Electronic address: jcfraile@eii.uva.es. ITAP (Instituto de Tecnologías Avanzadas de la Producción), University of Valladolid, School of Industrial Engineering, Paseo del Cauce, 59, 47011 Valladolid, Spain. Electronic address: turiel@eii.uva.es. AN - 32045796 AU - de la Fuente López, E. AU - Muñoz García, Á AU - Santos Del Blanco, L. AU - Fraile Marinero, J. C. AU - Pérez Turiel, J. DA - Jul DO - 10.1016/j.cmpb.2020.105378 DP - NLM ET - 2020/02/12 KW - Computer-aided-surgery Convolutional Neural Networks Gossypiboma Image Texture Analysis Local Binary Patterns (LBP) Minimally Invasive Surgery interest. LA - eng N1 - 1872-7565 de la Fuente López, Eusebio Muñoz García, Álvaro Santos Del Blanco, Lidia Fraile Marinero, Juan Carlos Pérez Turiel, Javier Journal Article Ireland Comput Methods Programs Biomed. 2020 Jul;190:105378. doi: 10.1016/j.cmpb.2020.105378. Epub 2020 Feb 4. PY - 2020 SN - 0169-2607 SP - 105378 ST - Automatic gauze tracking in laparoscopic surgery using image texture analysis T2 - Comput Methods Programs Biomed TI - Automatic gauze tracking in laparoscopic surgery using image texture analysis VL - 190 ID - 241 ER - TY - JOUR AB - Objective: To determine the cellular effects of providing a fascial interface around subcutaneously-placed silicone implants, in terms of capsule thickness, myofibroblast/fibroblast cell count and inflammatory cell count. Study Design: Interventional, comparative study. Place and Duration of Study: Istanbul University Cerrahpasa Medical Faculty, Laboratory of Experimental Animals, Istanbul, Turkey, from May to September 2008. Methodology: A total of 16 adult New Zealand male rabbits with mean weight of 2508 ± 360 g were used in the study. Animals were divided into two groups as experiment and control groups with equal number of rabbits in each. Fascia injection was applied on silicone implant in the experiment group and compared with the control group in terms of capsule thickness, myofibroblast/fibroblast cell count and inflammatory cell count. At the end of the experiment, tissue samples were examined macroscopically and microscopically for the above. Statistical analysis of data was performed using student's t-test. Results: A statistically significant difference was found between experiment group and control group in terms of mean capsule thickness, mean myofibroblast and fibroblast cell counts and cell density (p < 0.05, each). Conclusion: Fascia tissue barrier prevent silicone rod reaction and foreign body reaction developing against silicone prosthesis in the studied animal model. AD - Department of Plastic and Reconstructive Surgery, Haydarpasa Numune Research and Teaching Hospital, Istanbul, Turkey Department of Biophysics, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey Department of Paediatric Genetic Laboratory, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey Department of Pathology, Haydarpasa Numune Research and Teaching Hospital, Istanbul, Turkey AU - Tuncel, N. AU - Tuncel, H. AU - Bayrak, I. AU - Gunes, P. AU - Uzunismail, M. A. DB - Scopus IS - 11 KW - Fascia. Silicone implant. Rabbit. Silicone rod reaction. Foreign body reaction M3 - Article N1 - Export Date: 10 November 2020 PY - 2012 SP - 707-710 ST - Autologous fascia graft as a biological barrier to silicone application in rabbits T2 - Journal of the College of Physicians and Surgeons Pakistan TI - Autologous fascia graft as a biological barrier to silicone application in rabbits UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84871993068&partnerID=40&md5=4ac4b869e2bbb828e80568871b82d56f VL - 22 ID - 1354 ER - TY - JOUR AB - PURPOSE: Autogenous bone has been used with success as implants in intrabony defects, because of its biological advantages and osteogenic potential. The objective of this study was to evaluate histological and histometrically the bony repair in intrabony defects after dental extractions in rats with graft of a combination of the enamel matrix protein (EMP) (Emdogain, Strauman USA, LLC, Andover, MA. Headquarters in Basel, Switzerland) and autogenous bone. MATERIALS AND METHODS: Male rats (Rattus norvegicus, Wistar variety) weighing from 250 to 300 g were anesthetized and submitted to the extraction of the superior incisive and divided in (a) group with autogenous bone (fragment of bone of the alveolar ridge was grafted inside the alveolus) and (b) group with autogenous bone associated with EMP. The animals were killed on the 7th, 21st, and 42nd day after the extraction. The maxillae were processed to obtain fine sections (5 μm) stained with hematoxylin-eosin. The percentual volume of bone tissue in contiguous areas of the graft was calculated through a counting point system of image. RESULTS: The results showed that the bone fragments grafted in the cervical third of the alveolus developed a progressive osseointegration without foreign-body reaction. The quantification of the bony repair in the areas adjacent to the graft showed that the autogenous bone associated with EMP produced a greater amount of bone (10%-15% by analysis of variance, P = 0.05) in all the studied periods. CONCLUSIONS: It was concluded that the autogenous bone associated with EMP grafted in bony defects, immediately after the dental extraction in rats, demonstrated biocompatibility and accelerated the repair of bone defect. © 2007 Lippincott Williams & Wilkins, Inc. AD - Department of Morphology, Stomatology and Physiology, Dentistry School, University of São Paulo-USP, Ribeirão Preto, Sao Paulo, Brazil Department of Morphology, Stomatology and Physiology, Dentistry School, University of São Paulo-USP, Ribeirão Preto, Avenida do Café s/n, 14040-904, Ribeirão Preto, Sao Paulo, Brazil AU - Prata, C. A. AU - Lacerda, S. A. AU - Brentegani, L. G. DB - Scopus DO - 10.1097/ID.0b013e31815705a5 IS - 4 KW - Autogenous bone Bony repair Enamel matrix protein M3 - Article N1 - Cited By :8 Export Date: 10 November 2020 PY - 2007 SP - 413-420 ST - Autogenous bone graft associated with enamel matrix proteins in bone repair T2 - Implant Dentistry TI - Autogenous bone graft associated with enamel matrix proteins in bone repair UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-37349075362&doi=10.1097%2fID.0b013e31815705a5&partnerID=40&md5=0ec093ebe6934a74472fa10cdced7ca3 VL - 16 ID - 1545 ER - TY - JOUR AD - Clarian Health Partners, Indianapolis, USA. AU - Farrell, V. AU - Higbie, V. AU - Cleveland, S. DB - Scopus IS - 3 M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2003 SP - 13-14 ST - Auditing and improving the sponge count process T2 - OR manager TI - Auditing and improving the sponge count process UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037360024&partnerID=40&md5=cd88c0ae386758d073c264f85c9909e9 VL - 19 ID - 1651 ER - TY - JOUR AB - Objectives: Correlation between operative site skin bacterial counts in neurosurgical procedures and the development of surgical site infections (SSI) has not been proven. We evaluated the association of bacterial Colony Forming Units(CFU), type of procedure and development of SSI in a prospective pilot study Methods: Skin swab cultures were obtained within 1 cm from the incision; pre-, post-preparation and preclosure samples were obtained. Bacterial counts were enumerated and the most prevalent organisms were recorded. Procedures were classified as clean, clean with foreign body, clean contaminated, contaminated and dirty Results: 83 procedures (42.1% clean, 21.7% clean-contaminated, 18% clean with foreign body, 14.5% contaminated and 4.8% dirty) in 70 patients(70% male) were evaluated prospectively. Trauma was the most common reason for surgery (31.8%). 93 sample sets were cultured. 88.2% preprep, 28% postprep and 43.5% of the preclosure samples tested positive. Coagulase-negative staphylococci (CoNS) were the most frequently isolated organisms irrespectively of sampling time (62.4%, 18.3% and 29.3% for samples 1, 2 and 3 respectively) and independently of procedure classification. The median cfu count log for CoNS were 3 log(range 2-6.3), 2.6(range 2-3.7) and 2.4(range 2-4) respectively for each sampling. P. acnes was the second most frequent pathogen isolated. The median cfu count log for P. acnes were 3.9 log (range 2.2-6.6), 3.2 (range 2-3.8) and 4.3 (range 2-5.4) respectively for each sampling. There was a significant difference in the P. acnes counts isolated from head versus other sites. Procedure classification or prolonged surgery duration were not associated with microbial counts irrespectively of sampling time. SSI development was not associated with bacterial CFU at any sampling, therefore there was a trend for association with CoNS pre-preparation CFU. Conclusion: CoNS was the most frequent bacterial pathogen cultured irrespectively of sampling. The pathogen cfu log did not significantly differ among the samples. P. acnes was significantly more isolated from head specimens. Procedure classification was not associated with microbial skin counts at any sampling but CoNS prepreparation CFU carried a trend for statistical association with SSI development in this pilot study. AD - I. Kourbeti, Heraklion, Athens, Chalkida, Greece AU - Maraki, S. AU - Karabetsos, D. AU - Tsiodras, S. AU - Kourbeti, I. AU - Ioannou, A. AU - Neophytou, C. AU - Filippou, M. AU - Vakis, A. DB - Embase DO - 10.1111/j.1469-0691.2009.02858.x KW - classification infection neurosurgery microbiology sampling Propionibacterium acnes colony forming unit pathogenesis skin pilot study foreign body bacterial count bacterium colony incision patient male injury surgery coagulase negative Staphylococcus operation duration LA - English M3 - Conference Abstract N1 - L70071893 2010-03-08 PY - 2009 SN - 1198-743X SP - S554 ST - Associations between operative site microbial counts and procedure classification in neurosurgery T2 - Clinical Microbiology and Infection TI - Associations between operative site microbial counts and procedure classification in neurosurgery UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70071893&from=export http://dx.doi.org/10.1111/j.1469-0691.2009.02858.x VL - 15 ID - 582 ER - TY - JOUR AB - Objective: Correlation between operative site skin bacterial counts in neurosurgical procedures and the development of surgical site infections (SSI) has not been proven. We evaluated the association of bacterial Colony Forming Units (CFU), type of procedure and development of SSI in a prospective pilot study. Methods: Skin swab cultures were obtained within 1 cm from the incision;pre-,post-preparation and preclosure samples were obtained. Bacterial counts were enumerated and the most prevalent organisms were recorded. Procedures were classified as clean, clean with a foreign body, clean contaminated, contaminated and dirty. Results: 157 procedures (43.9% clean, 19.1% clean-contaminated, 26.1% clean with foreign body, 7.6% contaminated and 3.2% dirty) in 118 patients (62.4% male) were evaluated prospectively. 38.9%patients were hospitalized in the ICU. Oncology and trauma were the most common reasons for surgery (28% and 26.8% respectively). 157 sample sets were cultured. 85.4% pre-prep,27% post-prep and 43.9% of the preclosure samples tested positive. Coagulase-negativestaphylococci (CoNS) were the most frequently isolated organisms irrespectively of sampling time (65%, 17.8% and 27.4% for samples 1, 2 and 3 respectively) and independently of procedure classification followed by P. acnes. The median cfu count log for CoNS were 2.97log (IQR 2.47- 3.73), 2.48 (range 2-2.76) and 2.47 (IQR 2-2.69) respectively for each sampling.P. acnes was the second most frequentpathogen isolated. The median cfu count log for P. acnes were 4.25log (IQR 3-4.58), 2.87 (IQR 2.48-3.43) and 4.3 (IQR 3.35-4.69)respectively for each sampling. There was a significant difference in rates of pathogens in preprep samples for the head compared to other sites (OR 2.9,p= 0.028). The same was true for the P. acnes isolated from head versus other sites for preprep and postprep samples (OR 5.2, p = 0.01 and OR 1.16, p = 0.024 repectively). Procedure classification or prolonged surgery duration were not associated with microbial counts irrespectively of sampling time. SSI development was not associated with bacterial CFU at any sampling but with ICU stay (p<0.001). Conclusion: CoNS and P. acnes were the most frequent bacterial pathogen cultured irrespectively of sampling. The pathogen cfu log did not significantly differ among the samples. P. acnes isolation correlated with head specimens. Procedure classification was not associated with microbial skin counts at any sampling. SSI was associated with ICU stay. AD - I. Kourbeti, Athens, Greece AU - Kourbeti, I. AU - Tsiodras, S. AU - Maraki, S. AU - Karabetsos, D. AU - Neophytou, C. AU - Filippou, M. AU - Ioannou, A. AU - Vakis, A. DB - Embase DO - 10.1111/j.1469-0691.2011.03558.x KW - coagulase classification neurosurgery sampling Propionibacterium acnes skin pathogenesis human patient foreign body bacterial count colony forming unit infection operation duration bacterium colony incision male oncology pilot study surgery acne injury LA - English M3 - Conference Abstract N1 - L70600303 2011-12-08 PY - 2011 SN - 1198-743X SP - S470 ST - Associations between operative site microbial counts and procedure classification in neurosurgery T2 - Clinical Microbiology and Infection TI - Associations between operative site microbial counts and procedure classification in neurosurgery UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70600303&from=export http://dx.doi.org/10.1111/j.1469-0691.2011.03558.x VL - 17 ID - 544 ER - TY - JOUR AB - HYPOTHESIS: Retained surgical sponges are serious medical errors that result in negative patient outcomes. A radiofrequency (RF) mat for the operating room bed has recently been introduced to detect the presence of a retained surgical sponge. The study objectives were to evaluate the sensitivity and specificity of the RF mat for the detection of surgical sponges through the torso of individuals with varying body habitus and to compare the sensitivity of the RF mat with that of the RF wand. We hypothesized that the sensitivity and specificity of the RF technology would be comparable to published findings of the manual sponge count by operating room personnel. DESIGN: A prospective, crossover, double-blinded study design was used. Participants served as their own controls. SETTING Large Midwestern academic medical center. PARTICIPANTS: In total, the first phase of the study enrolled 203 participants, including 129 (63.5%) with morbid obesity. One hundred seventeen of 203 participants were also enrolled in the second phase of the study. MAIN OUTCOME MEASURES: The study participants reclined in a supine position on top of an RF mat. Four surgical sponges were sequentially placed on top of the torso in locations approximating the abdominal quadrants. The torso was scanned for sponges. In a subset of participants, 4 surgical sponges were sequentially placed underneath the torso, and an RF wand was passed over the abdomen. RESULTS: Overall, 812 readings were obtained with the RF mat, and 468 readings were obtained with the RF wand. Twelve false-negative readings were obtained with the RF mat, exclusively in participants with super morbid obesity (body mass index [calculated as weight in kilograms divided by height in meters squared] >50.0). Overall, the sensitivity of the RF mat was 98.1%, and the specificity of the RF mat was 100.0%. In the subset of 117 participants in whom the RF wand was also used, the sensitivity and specificity of the wand were each 100.0%. CONCLUSIONS: The sensitivity and specificity of RF device technology are much higher than those of surgical sponge counts or published findings on the use of intraoperative radiographs to identify retained surgical sponges. The RF wand is more sensitive than the RF mat in individuals with morbid obesity. AD - College of Nursing, The University of Iowa, IowaCity, IA, USA. victoria-steelman@uiowa.edu AN - 23070411 AU - Steelman, V. M. AU - Alasagheirin, M. H. DA - Oct DO - 10.1001/archsurg.2012.1556 DP - NLM ET - 2012/10/17 IS - 10 KW - Adolescent Adult Aged Cross-Over Studies Double-Blind Method Equipment Design False Negative Reactions Female Foreign Bodies/*diagnosis/*etiology Humans Male Medical Errors/*adverse effects Middle Aged Monitoring, Intraoperative/instrumentation/methods Obesity, Morbid/*surgery Postoperative Complications/diagnosis/etiology/*prevention & control Predictive Value of Tests Prospective Studies *Radio Waves Sensitivity and Specificity *Surgical Sponges/adverse effects Young Adult LA - eng N1 - 1538-3644 Steelman, Victoria M Alasagheirin, Mohammad H Comparative Study Evaluation Study Journal Article Research Support, Non-U.S. Gov't United States Arch Surg. 2012 Oct;147(10):955-60. doi: 10.1001/archsurg.2012.1556. PY - 2012 SN - 0004-0010 SP - 955-60 ST - Assessment of radiofrequency device sensitivity for the detection of retained surgical sponges in patients with morbid obesity T2 - Arch Surg TI - Assessment of radiofrequency device sensitivity for the detection of retained surgical sponges in patients with morbid obesity VL - 147 ID - 129 ER - TY - JOUR AB - Introduction: Foreign body aspiration (FBA) is still an important cause of mortality and morbidity in all over the world which is preventable. in this study, the analyse of our clinical data of the patients who underwent bronchoscopy for FBA and review of the literature was done. Objectives: The aim of the study is to analyse the epidemiological and clinical data of the patients who underwent bronchoscopy for FBA from November 2006 - August 2012 at Gazi University Faculty of Medicine Pediatric Surgery Department, retrospectively and to compare the findings with the literature to determine preventing strategies. Material/Patients and Methods: The patients' genders, ages, symptoms, physical findings, witnessed choking crisis, the activity during event, time elapsed from aspiration to presentation, radiological findings, type of the bronchoscopy, presentation of foreign body (FB), negative bronchoscopy rate, type of the FB, localization of the FB, complications, hospital stay, white blood cell counts, existance of siblings, diagnosis and treatment for upper respiratory tract infections before bronchoscopy, the medications applied before and after bronchoscopy were recorded after an archive scanning. Results: 35,82% of the patients were girls, 64,18% were boys. the median age was 31,1 months. FBA mostly seen in 1-3 age group (71,64%). a FB was found in 79,1% of patients, the negative bronchoscopy rate was 20,9%. 87,74% of FBs were organic and 12,26% were inorganic. Most common organic FBs were hazelnut, seed and walnut (respectively 18%, 16% and 14%). the FBs were found 49,53% in the right and 41,69% in the left bronchial tree. But in the group of 1-3 age the left and right bronchial tree localizations were found equal (43,84%). 26,87% of patients were presented with a history of aspiration at the same day and 14,93% with a history of more than 2 weeks. Adult presentation during the aspiration was 77%. Most common sypmtoms were wheezing (30,1%) and coughing (29,77%). Most common oscultation findings were unilateral loss of breath sounds (33,33%) and wheezing (20,11%). Most common radiological finding was unilateral air trapping with 66% the radiological examination were normal in 35,82% of the patients. Steroids, ventolin and antibiotics were given 39,55%, 55% and 93% respectively. 52,9% of the patients had siblings. 42,54% were diagnosed and treated for upper respiratory tract infections before bronchoscopy. Mean hospital stay was 1,9 days the complication rate was 8,9% and the mortality rate was 0%. Conclusion: FBA is a worldwide public health problem in pediatric population the numbers of cases can be reduced by determining proper preventions for the children under risk. It is needed to define regulatory standards for baby and child products manufacture and appropriate labelling practices like developed countries; public education campaigns and enhancing the public awareness about FBA. AD - B. Can, Gazi University, Faculty of Medicine, Pediatric Surgery Department, Turkey AU - Can, B. AU - Şen, M. C. AU - BaŞaklar, A. C. AU - Sönmez, K. AU - Türkyilmaz, Z. AU - Karabulut, R. DB - Embase DO - 10.1159/000351978 KW - steroid salbutamol antibiotic agent foreign body aspiration human childhood society surgery physical examination bronchoscopy patient aspiration upper respiratory tract infection wheezing tracheobronchial tree mortality hospitalization child sibling clinical study drug therapy diagnosis male abnormal respiratory sound public health problem leukocyte count coughing female adult foreign body morbidity walnut plant seed hazelnut gender groups by age boy radiodiagnosis pediatric surgery baby girl risk population prevention information center university developed country education LA - English M3 - Conference Abstract N1 - L71094662 2013-06-28 PY - 2013 SN - 0014-312X SP - 68 ST - The assessment of history, physical examination, radiological findings and bronchoscopic findings of childhood tracheobronchial foreign body aspirations T2 - European Surgical Research TI - The assessment of history, physical examination, radiological findings and bronchoscopic findings of childhood tracheobronchial foreign body aspirations UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71094662&from=export http://dx.doi.org/10.1159/000351978 VL - 50 ID - 483 ER - TY - JOUR AB - Introduction: Hypersensitivity pneumonitis is a type IV hypersensitivity reaction of the lung to inhaled antigens. Typically organic materials serve as the antigenic stimulus for this reaction. Acute, subacute and chronic manifestations of this condition have been described. Case description: We present a case of a 37 year old white male who is referred to Pulmonary Clinic for evaluation of cough and hypoxia. His medical history was significant for laparoscopic gastric banding for obesity, depression and chronic back pain. Two months prior to presentation he was in his normal state of health when he developed an acute flu-like illness. At that time, he complained of cough, fever and dyspnea that progressed until he ultimately required hospitalization. On admission he was hypoxemic and a CT scan of his chest revealed multi-focal ground glass opacities in his upper lobes along with innumerable centrilobular nodules bilaterally. He did have a peripheral leukocytosis, but all cultures including blood, sputum and bronchoalveolar lavage were negative. Symptoms gradually improved and he was discharged home on 2 liters of continuous oxygen. Over the next two months he developed similar symptoms requiring two subsequent hospitalizations. No infectious etiology was identified to explain his clinical symptoms and pulmonary infiltrates. He was then sent for second opinion. Complete blood count, chemistry, liver function, auto-immune serologies and hypersensitivity pneumonitis panel were all unremarkable. Bronchoscopy revealed slightly inflamed airways but no exudate. Upon removal of the bronchoscope, he coughed up a partially digested pill fragment. Trans-bronchial lung biopsy was negative for infection but did reveal a granulomatous inflammation associated with birefringent rod-like foreign particles. The morphology and histochemical features were consistent with microcrystalline cellulose which is a common tablet filler. He was started on systemic corticosteroids and quickly improved clinically and radiographically. Ultimately, he required revision of his gastric banding to prevent further aspiration events. Discussion: The presence of microcrystalline cellulose in the lungs commonly results from intravenous injection of dissolved oral tablets. This substance along with other tablet excipients like talc, elicit a foreign body granulomatous reaction within the pulmonary vasculature when injected. Rarely, aspiration of pill contents can produce a similar inflammatory response. This patient had recently undergone laparoscopic gastric banding which, although rare, can predispose to aspiration events. The clinical and radiographic syndrome he developed was similar to hypersensitivity pneumonitis. Systemic steroids and antigen removal led to prompt recovery. AD - T.B. Anderson, Ohio State University Medical Center, Columbus, OH, United States AU - Anderson, T. B. AU - Parsons, J. P. DB - Embase KW - microcrystalline cellulose antigen oxygen steroid glass talc corticosteroid excipient allergic pneumonitis American society aspiration tablet gastric banding foreign body hospitalization human granulomatous inflammation coughing lung pill influenza health male backache serology exudate lung infiltrate obesity etiology stimulus sputum blood medical history leukocytosis lung blood vessel lung lavage thorax computer assisted tomography blood cell count liver function hypoxia bronchoscopy airway bronchoscope intravenous drug administration morphology dyspnea infection lung biopsy fever diseases inflammation patient hospital allergic reaction LA - English M3 - Conference Abstract N1 - L71981781 2015-09-08 PY - 2013 SN - 1073-449X ST - Aspiration of microcrystalline cellulose leading to hypersensitivity pneumonitis-like reaction T2 - American Journal of Respiratory and Critical Care Medicine TI - Aspiration of microcrystalline cellulose leading to hypersensitivity pneumonitis-like reaction UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71981781&from=export http://www.atsjournals.org/doi/pdf/10.1164/ajrccm-conference.2013.187.1_MeetingAbstracts.A6144 VL - 187 ID - 479 ER - TY - JOUR AB - INTRODUCTION: Foreign body aspirations, although more common amongst children and the elderly, can lead to severe infections. CASE PRESENTATION: A 33 year old male with no known past medical history presented with a 3 month history of fatigue, episodic fevers, and cough with productive sputum. Patient was seen in a walk in clinic at the onset of symptoms and was told that he had a bronchitis and he was prescribed a 5 day course of azithromycin which did not resolve his symptoms. He denied any weight loss or other constitutional symptoms. Also he denied having any recent sick contacts. Furthermore he had a recent HIV test which was negative. On admission, the patient was febrile to 39.2â°C, BP 90/56, HR 120, RR 26, 91% on 2L NC. Exam was significant for tachycardia, decreased breath sounds on the right lung base as compared to the left, and diaphoresis. Labs was significant for a wbc count of 39 K/mcL. Otherwise unrevealing. An XR of the chest revealed foreign body aspiration in the right intermediate bronchus with superimposed pneumonia. Upon further questioning, it was illicited that the patient was involved in an altercation where he presumably lost his imitation gold teeth cover. The patient was started on broad spectrum Vancomycin and Zosyn. He continued to remain hypotensive and febrile despite broad antibiotic coverage. Interventional pulmonology was consulted. A bronchoscopy was performed with retrieval of the foreign object. The retrieval of the object was complicated by formation of granulation teeth; however it was finally able to be retrieved. Given the extent of granulation tissue, the patient underwent a significant amount of laser ablation of lung tissue. Over the next few days, the patient deferversed and improved clinically. DISCUSSION: Foreign body in the bronchus can present with variable symptoms depending on the severity. These can range from nonspecific respiratory complaints to long-term irreversible damage. Prompt recognition of the aspiration of the foreign body is important to identify as inflammatory granulation can develop as occurred with our patient. CONCLUSIONS: Foreign body aspiration can lead to severe infections. Prompt recognition is essential to prevent the sequelae of inflammatory granulation. AD - A. Patel, Emory University, School of Medicine, Atlanta, GA, United States AU - Patel, A. AU - Nunnery, E. AU - Adhyaru, B. DB - Embase DO - 10.1378/chest.1390925 IS - 4 KW - gold antihypertensive agent vancomycin azithromycin piperacillin plus tazobactam antibiotic agent aspiration tooth pneumonia granulation tissue human patient foreign body aspiration foreign body infection bronchus thorax bronchitis hospital pulmonology bronchoscopy lung parenchyma body weight loss imitation child sputum leukocyte count coughing diaphoresis fever fatigue lung abnormal respiratory sound tachycardia medical history HIV test laser surgery male aged Human immunodeficiency virus LA - English M3 - Conference Abstract N1 - L71072363 2013-06-06 PY - 2012 SN - 0012-3692 ST - Aspiration of fake gold teeth leading to severe pneumonia and granulation tissue formation T2 - Chest TI - Aspiration of fake gold teeth leading to severe pneumonia and granulation tissue formation UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71072363&from=export http://dx.doi.org/10.1378/chest.1390925 http://journal.publications.chestnet.org/article.aspx?articleid=1376939 VL - 142 ID - 506 ER - TY - JOUR AN - 104601500. Language: English. Entry Date: 20120120. Revision Date: 20200708. Publication Type: journal article DB - ccm DO - 10.2345/0899-8205-45.6.425 DP - EBSCOhost IS - 6 KW - Computer Communication Networks -- Standards Critical Care Equipment Maintenance Inventories Warming Techniques -- Equipment and Supplies Equipment and Supplies Risk Assessment Surgical Count Procedure N1 - questions and answers. Journal Subset: Allied Health; Biomedical; Peer Reviewed; USA. NLM UID: 8905560. PMID: NLM22107461. PY - 2011 SN - 0899-8205 SP - 425-425 ST - Ask George T2 - Biomedical Instrumentation & Technology TI - Ask George UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104601500&site=ehost-live&scope=site VL - 45 ID - 911 ER - TY - JOUR AB - Carotid endarterectomy plays an important role in the prevention of ischemic stroke; patching could reduce the risk of intra- and postoperative complications and late restenosis among primary closure. Materials actually available for the patch tailoring are synthetic or biological: which is the best is still debated. We present the case of a polyurethane (PU) carotid patch rejection three years after its implant, with no evident arterial discontinuity and no sign of infection. Histopathological analysis on hematoxylin-eosin stained sections of the regenerated arterial wall tissue removed revealed plasma cell infiltration and clusters of foreign body giant cells. PU patch rejection has been seldom described in literature. This is an unusual late complication that should be considered at long-term follow-up evaluation of these patients. AD - Vascular Surgery, San Raffaele Scientific Institute, Vita-Salute University, Milan, Italy Department of Pathology, San Raffaele Scientific Institute, Vita-Salute University, Milan, Italy AU - Tshomba, Y. AU - De Dominicis, D. AU - Marone, E. M. AU - Mascia, D. AU - Sanvito, F. AU - Chiesa, R. DB - Scopus IS - 6 KW - Endarterectomy, carotid Rejection Stroke M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2011 SP - 859-861 ST - Aseptic polyurethane carotid patch rejection: Complication, allergy or miraculous healing? T2 - Journal of Cardiovascular Surgery TI - Aseptic polyurethane carotid patch rejection: Complication, allergy or miraculous healing? UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84055222486&partnerID=40&md5=f828f97ef4e17f0b287e69660cab2d06 VL - 52 ID - 1402 ER - TY - JOUR AB - Background Failed metal-on-metal (MoM) bearings are being increasingly encountered with little information to guide evaluation for aseptic lymphocytic-dominated vasculitis-associated lesions (ALVAL). It is often assumed that elevated metal ion levels correlate with the occurrence of ALVAL. Our purpose was to determine the utility of the erythrocyte sedimentation rate, C-reactive protein, synovial white blood cell count, differential (%PMN), and serum metal ion levels in diagnosing ALVAL. Methods We identified 80-failed MoM total hip arthroplasties. Tissue was examined under light microscopy and graded on a scale of ALVAL severity. Mean laboratory values were compared between groups and receiver operating curves generated with an area under the curve to determine test performance and optimal cutoffs. Results ALVAL scores were graded as low in 30 (37.5%), moderate in 39 (49%), and severe in 8 (10%), with 3 being unreadable. No clear cutoff values for erythrocyte sedimentation rate, C-reactive protein, or synovial white blood cell count could be determined to reliably diagnose moderate or severe ALVAL. Furthermore, serum metal levels had no correlation with ALVAL score. The best test to diagnose ALVAL was the synovial fluid monocyte percentage with an optimal cutoff value of 39% and area under the curve of 69% (moderate testing performance). Conclusion The diagnosis of ALVAL remains challenging, with most of the screening tests being unreliable. Although serum metal ion levels are typically elevated in failed MoM bearings, higher levels do not appear to correlate with ALVAL grade. Elevated synovial fluid monocytes may provide diagnostic utility for ALVAL, suggesting a possible delayed-type hypersensitivity reaction. © 2016 Elsevier Inc. AD - Department of Orthopaedic Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, California, United States Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, United States AU - Plummer, D. R. AU - Yi, P. H. AU - Jacobs, J. J. AU - Urban, R. M. AU - Moric, M. M. AU - Della Valle, C. J. DB - Scopus DO - 10.1016/j.arth.2016.11.020 IS - 4 KW - adverse local tissue reaction ALVAL aseptic lymphocytic-dominated vasculitis-associated lesions failed metal-on-metal bearing metal ion levels M3 - Article N1 - Cited By :4 Export Date: 10 November 2020 PY - 2017 SP - 1340-1343 ST - Aseptic Lymphocytic-Dominated Vasculitis-Associated Lesions Scores Do Not Correlate With Metal Ion Levels or Unreadable Synovial Fluid White Blood Cell Counts T2 - Journal of Arthroplasty TI - Aseptic Lymphocytic-Dominated Vasculitis-Associated Lesions Scores Do Not Correlate With Metal Ion Levels or Unreadable Synovial Fluid White Blood Cell Counts UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85008870881&doi=10.1016%2fj.arth.2016.11.020&partnerID=40&md5=98a3357e06f32a142abb01dd10a5889e VL - 32 ID - 1139 ER - TY - JOUR AB - PURPOSE: To evaluate the efficacy, predictability, and safety of the Artisan iris claw phakic intraocular lens for the correction of high primary and secondary hyperopia. METHODS: Fifty-seven eyes were divided into two groups: 29 eyes had primary hyperopia (mean refraction 6.06 ± 1.26 D, and 28 eyes had secondary hyperopia, (mean refraction 5.88 ± 1.88 D) induced or residual following a previous corneal refractive procedure. Consecutive implantation of the Artisan iris claw phakic intraocular lens was performed. Main outcome measures recorded were BSCVA, UCVA, refraction, and astigmatic change, intraocular inflammation, and endothelial cell loss. RESULTS: Primary hyperopic group: Preoperatively, mean UCVA was 0.4 ± 0.7 and mean BSCVA was 0.2 ± 0.6. After implantation, mean UCVA was 0.3 ± 0.6 and BSCVA was 0.1 ± 0.6. Mean cycloplegic residual spherical refractive error after surgery was 0.10 ± 0.57 D (range -1 to +2 D). Mean surgically induced astigmatism was 1.48 ± 0.89 D. Safety index was 1.11. Efficacy index was 0.83. Secondary hyperopic group: Preoperatively, mean UCVA was 0.5 ± 0.7 and mean BSCVA was 0.2 ± 0.6. Postoperatively, mean UCVA was 0.4 ± 0.7 and mean BSCVA was 0.2 ± 0.6. Mean cycloplegic residual spherical refractive error was 0.55 ± 1.49 D. Mean surgically induced astigmatism was 1.85 ± 1.19 D. Safety index was 1.05. Efficacy index was 0.7. Postoperative iridocyclitis was observed in one eye (3.4%) in the primary group and in three eyes (10.7%) in the secondary group. Overall corneal endothelial cell loss at 1 year of follow-up was 9.4%. CONCLUSION: The Artisan iris claw phakic intraocular lens was reasonably safe and predictable for correcting high hyperopia. AD - Inst. Oftalimologico de Alicante, Department of Ophthalmology, Miguel Hernández University, Avda. Denia, III, 03015 Alicante, Spain Department of Ophthalmology, Cairo University, Medical School, Cairo, Egypt AU - Alió, J. L. AU - Mulet, M. E. AU - Shalaby, A. M. M. DB - Scopus IS - 6 M3 - Article N1 - Cited By :58 Export Date: 10 November 2020 PY - 2002 SP - 697-707 ST - Artisan phakic iris claw intraocular lens for high primary and secondary hyperopia T2 - Journal of Refractive Surgery TI - Artisan phakic iris claw intraocular lens for high primary and secondary hyperopia UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036859745&partnerID=40&md5=74d6e3318e82cfe3ecdc1237e7b42535 VL - 18 ID - 1656 ER - TY - JOUR AB - The principles for management of infectious complications in cancer patients are continuing to evolve. The critical element includes the prompt institution of broad-spectrum antibiotic(s) empirically when granulocytopenic patients become febrile and continuation and modification of the regimen in patients with persistent fever and granulocytopenia. The view is presented that antibiotics provide systemic prophylaxis as well as therapy in persistently granulocytopenic patients and that they should be continued until all signs of infection have cleared or the granulocyte count has recovered. Such aggressive therapy, supplemented by continued evaluation and monitoring of the patient, can significantly reduce infection-relation morbidity and mortality. © 1984. AU - Pizzo, P. A. AU - Commers, J. AU - Cotton, D. AU - Gress, J. AU - Hathorn, J. AU - Hiemenz, J. AU - Longo, D. AU - Marshall, D. AU - Robichaud, K. J. DB - Scopus DO - 10.1016/0002-9343(84)90663-6 IS - 3 M3 - Article N1 - Cited By :91 Export Date: 10 November 2020 PY - 1984 SP - 436-449 ST - Approaching the controversies in antibacterial management of cancer patients T2 - The American Journal of Medicine TI - Approaching the controversies in antibacterial management of cancer patients UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021367136&doi=10.1016%2f0002-9343%2884%2990663-6&partnerID=40&md5=650ed07109678c3ccef4be90f3e2f898 VL - 76 ID - 1757 ER - TY - JOUR AB - OBJECTIVE: The aim of this study was to assess the risk factors and preventive measures for gossypibomas and their medico-legal implications in forensic medicine in the Turkish legal system. MATERIAL AND METHODS: This study involved a retrospective analysis of the records of 39 patients with gossypiboma. Records were available from the Istanbul Forensic Medicine Institution and were surveyed for faulty treatment between 2008 and 2012. Parameters such as distribution of the cases according to specializations, elective and emergency procedures, surgical procedures, radio-opaque sponge and fluoroscopy availability, routine sponge and instrument counting, number of nurses for counting, and control of the operative field by a second surgeon were investigated. RESULTS: All cases were evaluated by the Istanbul Forensic Medicine Institute 3rd Expertise Committee. This committee comprised of specialists from the departments of forensic medicine, orthopedics and traumatology, general surgery, neurology, internal medicine, pediatrics, chest disease, and infectious diseases. All cases were considered as poor medical practice (malpractice) and surgeons were found to be responsible. In 16 of these 39 cases (41%) emergency procedures were performed. No unexpected event was reported in any procedure. In 16 cases (41%), sponge count was performed and was reported to be complete. Operation notes were available in 16 (41%) cases. Control of the operative field was performed by 1 surgeon, and sponge and instrument count was performed by 1 scrub nurse. Radio-opaque sponge and fluoroscopy were available in 9 (23%) centers in these cases. CONCLUSION: Gossypiboma can be prevented not only with surgeons' care but also with adequate support of medical device and material. However, it is considered as a poor medical practice. Presence of only 1 general surgeon in the expertise committee and ignorance of the working conditions by the surgeons should be questioned. AD - Department of Forensic Medicine Instution, İstanbul, Turkey. Clinic of Gastroentorology Surgery, Ministry Health Training and Research Hospital, Diyarbakır, Turkey. Department of General Surgery, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey. Clinic of General Surgery, Kartal Dr. Lütfi Kırdar Training and Research Hospital, İstanbul, Turkey. AN - 26170754 AU - Karakaya, M. A. AU - Koç, O. AU - Ekiz, F. AU - Ağaçhan, A. F. C2 - PMC4485816 DO - 10.5152/ucd.2015.2728 DP - NLM ET - 2015/07/15 IS - 2 KW - Gossypiboma complication forensic medicine surgery LA - eng N1 - 1308-8521 Karakaya, M Arif Koç, Okay Ekiz, Feza Ağaçhan, A Feran Journal Article Ulus Cerrahi Derg. 2015 Jun 1;31(2):78-80. doi: 10.5152/UCD.2015.2728. eCollection 2015. PY - 2015 SN - 1300-0705 (Print) 1300-0705 SP - 78-80 ST - Approach of forensic medicine to gossypiboma T2 - Ulus Cerrahi Derg TI - Approach of forensic medicine to gossypiboma VL - 31 ID - 164 ER - TY - JOUR AB - Despite innumerable attempts to eliminate the postoperative retention of surgical sponges, the medical error persists in operating rooms worldwide and places significant burden on patient safety, quality of care, financial resources, and hospital/physician reputation. The failure of countless solutions, from new sponge counting methods to radio labeled sponges, to truly eliminate the event in the operating room requires that the emerging field of health-care delivery science find innovative ways to approach the problem. Accordingly, the VA National Center for Patient Safety formed a unique collaboration with a team at the Thayer School of Engineering at Dartmouth College to evaluate the retention of surgical sponges after surgery and find a solution. The team used an engineering problem solving methodology to develop the best solution. To make the operating room a safe environment for patients, the team identified a need to make the sponge itself safe for use as opposed to resolving the relatively innocuous counting methods. In evaluation of this case study, the need for systematic engineering evaluation to resolve problems in health-care delivery becomes clear. AD - VA National Center for Patient Safety, White River Junction, Vermont, USA. AN - 23965835 AU - Anderson, D. E. AU - Watts, B. V. DA - Sep DO - 10.1097/PTS.0b013e3182831d9a DP - NLM ET - 2013/08/24 IS - 3 KW - Biomedical Engineering/*methods *Foreign Bodies Humans Medical Errors/*prevention & control Patient Safety/*standards Postoperative Complications/prevention & control *Surgical Sponges LA - eng N1 - 1549-8425 Anderson, Devon E Watts, Bradley V Journal Article Research Support, U.S. Gov't, Non-P.H.S. United States J Patient Saf. 2013 Sep;9(3):134-9. doi: 10.1097/PTS.0b013e3182831d9a. PY - 2013 SN - 1549-8417 SP - 134-9 ST - Application of an engineering problem-solving methodology to address persistent problems in patient safety: a case study on retained surgical sponges after surgery T2 - J Patient Saf TI - Application of an engineering problem-solving methodology to address persistent problems in patient safety: a case study on retained surgical sponges after surgery VL - 9 ID - 141 ER - TY - JOUR AB - Despite innumerable attempts to eliminate the postoperative retention of surgical sponges, the medical error persists in operating rooms worldwide and places significant burden on patient safety, quality of care, financial resources, and hospital/physician reputation. The failure of countless solutions, from new sponge counting methods to radio labeled sponges, to truly eliminate the event in the operating room requires that the emerging field of health-care delivery science find innovative ways to approach the problem. Accordingly, the VA National Center for Patient Safety formed a unique collaboration with a team at the Thayer School of Engineering at Dartmouth College to evaluate the retention of surgical sponges after surgery and find a solution. The team used an engineering problem solving methodology to develop the best solution. To make the operating room a safe environment for patients, the team identified a need to make the sponge itself safe for use as opposed to resolving the relatively innocuous counting methods. In evaluation of this case study, the need for systematic engineering evaluation to resolve problems in health-care delivery becomes clear. AD - From the ∗VA National Center for Patient Safety, White River Junction, Vermont; †Thayer School of Engineering at Dartmouth College; and ‡Dartmouth Medical School, Department of Psychiatry, Hanover, New Hamphsire. AN - 113435605. Language: English. Entry Date: 20170321. Revision Date: 20170321. Publication Type: Article AU - Anderson, Devon E. AU - Watts, Bradley V. DB - ccm DO - 10.1097/PTS.0b013e3182831d9a DP - EBSCOhost IS - 3 KW - Problem Solving Retained Instruments Biomedical Engineering Surgical Count Procedure Patient Safety Human N1 - research; tables/charts. Journal Subset: Health Services Administration; Peer Reviewed; USA. NLM UID: 101233393. PY - 2013 SN - 1549-8417 SP - 134-139 ST - Application of an Engineering Problem-Solving Methodology to Address Persistent Problems in Patient Safety T2 - Journal of Patient Safety TI - Application of an Engineering Problem-Solving Methodology to Address Persistent Problems in Patient Safety UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=113435605&site=ehost-live&scope=site VL - 9 ID - 822 ER - TY - JOUR AB - Rationale for this case report: Many children are hospitalized because of foreign body ingestion. In such circumstances, the gastroenterologist must consider the timing of ingestion; the size, type, and location of the object ingested; and the patient's symptoms. But appendiceal foreign body in infant is very rare. Patient concerns: A 12-month-old boy visited because of swallowing small objects 2 weeks ago. Three small beads were found in the right lower quadrant on abdominal radiography. A 7-year-old boy was admitted for treatment of appendiceal foreign body, which was detected by accident 3 months ago. Diagnoses, interventions, and outcomes: A 7-year-old boy had abdominal pain and underwent immediate appendectomy. However, the 12-month-old child was asymptomatic, which led to deliberation in regard to wait time for an appendectomy in younger children with asymptomatic appendiceal foreign body. He underwent prophylactic appendectomy after 2 months. Main lessons: An appendiceal foreign body is very rare in infant and there are currently no treatment guidelines. We report 2 cases of appendiceal foreign body including infant who gave us difficult decisions. Copyright © 2017 the Author(s). AD - Department of Pediatrics, Chonbuk National University Medical School and Hospital, Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital, 20 Geonji-ro, Jeonju, 54907, South Korea AU - Lee, M. AU - Kim, S. C. C7 - e6717 DB - Scopus DO - 10.1097/MD.0000000000006717 IS - 17 KW - Appendectomy Appendicitis Foreign body M3 - Article N1 - Cited By :3 Export Date: 10 November 2020 PY - 2017 ST - Appendiceal foreign body in an infant T2 - Medicine (United States) TI - Appendiceal foreign body in an infant UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019198879&doi=10.1097%2fMD.0000000000006717&partnerID=40&md5=f8a740a3c1af9d85ed03823c5d60f484 VL - 96 ID - 1137 ER - TY - JOUR AB - The article discusses revisions which have been made to the Association of periOperative Registered Nurses' recommended practices for the prevention of retained surgical items, including surgical sponges and needles. The importance of having surgical staff count and recount all surgical items is discussed. AN - 54561307. Language: English. Entry Date: 20101103. Revision Date: 20101111. Publication Type: Article DB - ccm DP - EBSCOhost KW - Retained Instruments -- Prevention and Control Surgical Count Procedure AORN -- Standards Practice Guidelines N1 - brief item; practice guidelines. Supplement Title: Nov2010 Supplement. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7810150. PY - 2010 SN - 0190-5066 SP - 2-2 ST - AORN: Entire team needs to be involved T2 - Same-Day Surgery TI - AORN: Entire team needs to be involved UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=54561307&site=ehost-live&scope=site ID - 914 ER - TY - JOUR AN - 103951909. Language: English. Entry Date: 20140602. Revision Date: 20200708. Publication Type: Journal Article AU - Retzlaff, Kimberly J. DB - ccm DO - 10.1016/j.aorn.2014.04.005 DP - EBSCOhost IS - 6 KW - AORN Congresses and Conferences Education, Nursing, Continuing Hospital Design and Construction Operating Rooms Ambulatory Surgery Nursing Informatics Medical Waste Surgical Count Procedure Patient Safety Sterilization and Disinfection Central Service Department Outcomes (Health Care) Pain -- Therapy Legal Procedure Witness, Legal N1 - pictorial. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Nursing Education; Perioperative Care. NLM UID: 0372403. PMID: NLM24875204. PY - 2014 SN - 0001-2092 SP - 685-698 ST - AORN Surgical Conference & Expo Education Sessions T2 - AORN Journal TI - AORN Surgical Conference & Expo Education Sessions UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103951909&site=ehost-live&scope=site VL - 99 ID - 730 ER - TY - JOUR AB - This study compared the effect of an antioxidant on the in vivo biodegradation of a poly(carbonate urethane) (PCU) and a poly (ether urethane) (PEU). Unstrained PEU and PCU films with and without Santowhite® were implanted subcutaneously into 3-month-old Sprague-Dawley rats for 3, 6, and 12 months. Characterization of unstabilized PEU and PCU with ATR-FTIR and SEM showed soft-segment and hard-segment degradation consistent with previous studies. In particular, evidence of chain scission and crosslinking of the surface was present in the ATR-FTIR spectra of explanted specimens. Addition of 2.2 wt % antioxidant inhibited the in vivo degradation of both PCU and PEU. Although the antioxidant probably improved polyurethane biostability by decreasing the susceptibility of the polymer to degradation, modulation of the cellular response to prevent the release of degradative agents was also possible. To differentiate the effects, the foreign-body response was investigated with the use of a standard cage implant protocol. Polyurethane films were implanted in wire mesh cages subcutaneously in rats for 4, 7, and 21 days. There were no statistical differences among materials in the inflammatory exudate cell counts, adherent cell densities, or percent fusion of macrophages into foreign-body giant cells (FBGCs). Therefore, it was concluded that the antioxidant inhibited degradation by capturing oxygen radicals that would otherwise cause polyurethane chain scission and crosslinking. © 2005 Wiley Periodicals, Inc. AD - Center for Applied Polymer Research, Case Western Reserve University, Cleveland, OH 44106, United States Department of Macromolecular Science, Case Western Reserve University, Cleveland, OH 44106, United States Department of Biomedical Engineering, Institute of Pathology, Case Western Reserve University, Cleveland, OH 44106, United States AU - Christenson, E. M. AU - Anderson, J. M. AU - Hiltner, A. DB - Scopus DO - 10.1002/jbm.a.30506 IS - 3 KW - Antioxidant Biodegradation Foreign-body response In vivo Poly(carbonate urethane) Poly(ether urethane) M3 - Article N1 - Cited By :51 Export Date: 10 November 2020 PY - 2006 SP - 480-490 ST - Antioxidant inhibition of poly(carbonate urethane) in vivo biodegradation T2 - Journal of Biomedical Materials Research - Part A TI - Antioxidant inhibition of poly(carbonate urethane) in vivo biodegradation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-33645288879&doi=10.1002%2fjbm.a.30506&partnerID=40&md5=2d735a6a2b450052e4661409ddf747ec VL - 76 ID - 1586 ER - TY - JOUR AD - Dept. Obstet. Gynecol., Hahnemann Med. Coll. Hosp., Philadelphia, Pa. 19102, United States AU - Davis, R. H. AU - Kotwal, H. B. AU - Balin, H. DB - Scopus IS - 1 M3 - Article N1 - Export Date: 10 November 2020 PY - 1975 SP - 29 ST - Antifertility and uterine response to polyethylene intrauterine devices in rabbits T2 - IRCS MED.SCI.BIOMED.TECH. TI - Antifertility and uterine response to polyethylene intrauterine devices in rabbits UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0016408714&partnerID=40&md5=902cea33d72819d3e6b71d6d2b12412f VL - 3 ID - 1774 ER - TY - JOUR AB - Background: The purpose of this single case report was to report the use of anterior segment optical coherence tomography for the diagnosis and management of a retained vegetal intraocular foreign body. Results: A 23-year-old otherwise healthy male presented with a progressive vision loss in the right eye (RE). He reported a mild ocular trauma with a tree leaf 1 year ago followed by recurrent episodes of redness and pain in the RE that partially resolved after a self-medication with topical steroids. Visual acuity of the RE was limited to light perception. Slit-lamp examination of the RE showed an iris granuloma with overlying exudate and associated anterior chamber inflammatory reaction. Film X-rays, contact B-scan ultrasonography, and CT scan showed no abnormalities. Anterior segment optical coherence tomography revealed an enclaved iris foreign body. The foreign body was removed after a short course of local antibio-corticosteroid therapy. This was followed 2 months later by cataract surgery with intraocular lens implantation, with subsequent improvement of visual acuity to 20/40. Conclusions: A missed intraocular foreign body can lead to sight-threatening complications. Anterior segment optical coherence tomography may be useful for detecting non-clinically evident intraocular foreign body involving the anterior segment masquerading as chronic anterior uveitis. © 2017, The Author(s). AD - Department of Ophthalmology, Taher Sfar University Hospital, Faculty of Medicine, University of Monastir, Monastir, Tunisia Department of Ophthalmology, Fattouma Bourguiba University Hospital, Faculty of Medicine, University of Monastir, Monastir, 5019, Tunisia AU - Mahmoud, A. AU - Messaoud, R. AU - Abid, F. AU - Ksiaa, I. AU - Bouzayene, M. AU - Khairallah, M. C7 - 13 DB - Scopus DO - 10.1186/s12348-017-0130-7 IS - 1 KW - Anterior segment optical coherence tomography Masquerade syndrome Vegetal intraocular foreign body M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2017 ST - Anterior segment optical coherence tomography and retained vegetal intraocular foreign body masquerading as chronic anterior uveitis T2 - Journal of Ophthalmic Inflammation and Infection TI - Anterior segment optical coherence tomography and retained vegetal intraocular foreign body masquerading as chronic anterior uveitis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019768010&doi=10.1186%2fs12348-017-0130-7&partnerID=40&md5=ddb5d6a3be0eb982a333852098bf06f6 VL - 7 ID - 1109 ER - TY - JOUR AN - 106961311. Language: English. Entry Date: 20020920. Revision Date: 20150820. Publication Type: Journal Article. Journal Subset: Core Nursing AU - Beesley, J. DB - ccm DP - EBSCOhost IS - 7 KW - Surgical Count Procedure Perioperative Nursing -- Organizations United Kingdom Practice Guidelines N1 - Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 100935999. PMID: NLM12226951. PY - 2002 SN - 1467-1026 SP - 238-239 ST - Answers supplied...swab instrument and needle count T2 - British Journal of Perioperative Nursing TI - Answers supplied...swab instrument and needle count UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106961311&site=ehost-live&scope=site VL - 12 ID - 916 ER - TY - JOUR AN - 106928729. Language: English. Entry Date: 20020607. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Core Nursing AU - Beesley, J. DB - ccm DP - EBSCOhost IS - 2 KW - Surgical Count Procedure United Kingdom N1 - Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 100935999. PY - 2002 SN - 1467-1026 SP - 54-55 ST - Answers supplied...counting of the swabs T2 - British Journal of Perioperative Nursing TI - Answers supplied...counting of the swabs UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106928729&site=ehost-live&scope=site VL - 12 ID - 917 ER - TY - JOUR AN - 106432912. Language: English. Entry Date: 20060428. Revision Date: 20200316. Publication Type: Journal Article AU - Pirie, S. DB - ccm DO - 10.1177/175045890601600101 DP - EBSCOhost IS - 1 KW - Documentation Medical Records Perioperative Nursing Surgical Count Procedure Nursing Organizations Perioperative Nursing -- Standards United Kingdom N1 - questions and answers. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 10127103. PY - 2006 SN - 1750-4589 SP - 13-15 ST - Answers supplied: the need for accurate records T2 - Journal of Perioperative Practice TI - Answers supplied: the need for accurate records UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106432912&site=ehost-live&scope=site VL - 16 ID - 886 ER - TY - JOUR AB - Foreign bodies are commonly ingested and usually pass through the gastrointestinal tract, but in less than 1% complications can be seen. We aimed to report a very rare case of multiple hepatic abscesses caused by perforation of the sigmoid colon due to a chicken bone. An 82-year-old man presented with a 5-day history of abdominal pain, fever, and coffee ground vomiting. He was febrile and tachycardic and had a mild localized abdominal tenderness in the left lower quadrant. Laboratory findings revealed a lymphocyte dominant leukocytosis with an elevated erythrocyte sedimentation rate. Multiple abscesses were shown in the right lobe of the liver in abdominal computed tomography. Colonoscopy showed a chicken bone perforating both walls of the sigmoid colon. He received broad-spectrum antibiotics and underwent surgery for a complete recovery. Chronic lymphocytic leukemia was diagnosed by flow cytometry phenotyping. Mortality and morbidity of hepatic sepsis caused by foreign body-induced colon perforation depend on a rapid diagnosis. We presented a very rare condition that should always be kept in mind when dealing with a case of liver abscess and even while confronting septic shock with an unknown origin. © 2018 Tehran University of Medical Sciences. All rights reserved. AD - Department of Gastroenterology, Gastroenterology and Hepatology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran Department of Surgery, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran Department of Gastroenterology and Hepatology, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran AU - Sivandzadeh, G. AU - Banazadeh, A. AU - Anushiravani, A. DB - Scopus IS - 2 KW - Chicken bone Liver abscess Perforation M3 - Article N1 - Export Date: 10 November 2020 PY - 2018 SP - 127-131 ST - Angry bird's revenge: Hepatic abscesses secondary to colonic perforation T2 - Acta Medica Iranica TI - Angry bird's revenge: Hepatic abscesses secondary to colonic perforation UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85042158788&partnerID=40&md5=2f5bb8c7f39cf576dce8544110837b34 VL - 56 ID - 1098 ER - TY - JOUR AB - Implants of commercially pure titanium and polytetrafluoroethylene (PTFE) were inserted in the rat abdominal wall for 1, 6 or 12 wk. The foreign-body reaction was evaluated by immunohistochemical quantification of monocytes/macrophages and by the thickness of the foreign-body capsule. At all time intervals, the majority of interfacial cells were ED1-positive while ED2-positive cells were localized deeper in the tissue. Neither titanium nor PTFE displayed a significant change in capsule thickness over time. The total cell numbers decreased over time for both types of material. At 12 wk the PTFE implants, compared to titanium, were surrounded by a significantly thicker reactive capsule with larger total cell numbers. No significant differences were seen in the macrophage subset response between the two types of implants. Thus, the present study showed differences between titanium and PTFE at 12 wk but not at earlier time points. Implants of commercially pure titanium and polytetrafluoroethylene (PTFE) were inserted in the rat abdominal wall for 1, 6 or 12 wk. The foreign-body reaction was evaluated by immunohistochemical quantification of monocytes/macrophages and by the thickness of the foreign-body capsule. At all time intervals, the majority of interfacial cells were ED1-positive while ED2-positive cells were localized deeper in the tissue. Neither titanium nor PTFE displayed a significant change in capsule thickness over time. The total cell numbers decreased over time for both types of material. At 12 wk the PTFE implants, compared to titanium, were surrounded by a significantly thicker reactive capsule with larger total cell numbers. No significant differences were seen in the macrophage subset response between the two types of implants. Thus, the present study showed differences between titanium and PTFE at 12 wk but not at earlier time points. AD - Department of Experimental Research, University Hospital MAS, S-205 02 Malmö, Sweden Dept. of Physiology and Neuroscience, Neuroendocrine Cell Biology, Lund University Hospital, S-221 85 Lund, Sweden AU - Rosengren, A. AU - Bjursten, L. M. AU - Danielsen, N. DB - Scopus DO - 10.1023/A:1013239731256 IS - 7 M3 - Article N1 - Cited By :16 Export Date: 10 November 2020 PY - 1998 SP - 415-420 ST - Analysis of the inflammatory response to titanium and PTFE implants in soft tissue by macrophage phenotype quantification T2 - Journal of Materials Science: Materials in Medicine TI - Analysis of the inflammatory response to titanium and PTFE implants in soft tissue by macrophage phenotype quantification UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032128109&doi=10.1023%2fA%3a1013239731256&partnerID=40&md5=999609db8eb371aa019e2a0746a7307b VL - 9 ID - 1694 ER - TY - JOUR AB - Purpose: Although relatively uncommon, esophageal peforations still carry high morbidity and mortality. There are controversies about the management, especially concerning the thoracic esophagus, which have a higher mortality. We reviewed our experience in treating intrathoracic esophageal perforations and evaluated etiology, management, outcome and the factors associated with a poor outcome. Methods: Between 2004 and 2008, 30 patients were treated in our deparment with perforations of the intrathoracic esophagus. Etiology, time interval between clinical presentation and treatment, therapeutic management and outcome were analyzed as wells as heart rate, systolic blood pressure, albumin, leukocyte count upon arrival and need for blood transfusion or thoracothomy. Results: The most frequent cause was postdilatation corrosive stricture perforation (46.6%), followed by removal of foreign body (20.2%). Esophagectomy was the treatment of choice in 26 patients (86.8%), 65.4% of those through a transhiatal approach. Three patients underwent suture of the esophagus (10%), and one of the three received combined esophagostomy. One patient (3.3%) was submitted to an endoscopic clip placement. There was a 33% mortality rate. A high leukocytes count was statistically associated with complications. Conclusion: Our series had a survival rate similar to other publications. Esophagectomy was performed in the majority of cases due to a high incidence of underlying esophageal diseases. Besides the diagnostic interval linked to mortality we also found an association with high leukocytes count. AD - M. Chiera di Vasco Freitas, Santa Casa Medical, School of Sao Paulo, Brazil AU - Chiera di Vasco Freitas, M. AU - Gustavo Parreira, J. AU - Cesar Assef, J. AU - Gagliardi, D. AU - Castro Pochini, C. AU - Campos Padovese, C. DB - Embase DO - 10.1111/j.1442-2050.2010.01101.x KW - albumin esophagus esophagus perforation society human mortality patient leukocyte esophagus resection perforation etiology suture esophagostomy survival rate esophagus disease diagnosis morbidity heart rate systolic blood pressure leukocyte count blood transfusion foreign body clip LA - English M3 - Conference Abstract N1 - L70561147 2011-10-24 PY - 2010 SN - 1120-8694 SP - 131A ST - Analysis of intrathoracic esophageal perforations in a tertiary center T2 - Diseases of the Esophagus TI - Analysis of intrathoracic esophageal perforations in a tertiary center UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70561147&from=export http://dx.doi.org/10.1111/j.1442-2050.2010.01101.x VL - 23 ID - 562 ER - TY - JOUR AB - Of 100 consecutive operations on the knee 90 were for meniscal lesions, 69 of them affecting the medial cartilage. Five normal menisci were removed and in three of these cases relief was obtained. In the other two the lateral menisci were found to be torn and were removed afterwards. One case had both menisci torn and both were removed; another had 'discoid' medial cartilages removed from both knees at one sitting. An arthrography was used once and enabled a diagnosis of a bucket-handle tear of the lateral meniscus to be made. Five cysts of the menisci, one medial and four lateral, were removed. Once a pedunculated xanthoma was removed from the intercondyloid notch. This was examined and stated to be a benign histiocytoma. A Michel clip was removed from the knee joint in one case whose primary operation had been performed in another hospital. It is interesting that this author too uses clips, and now they are counted in the same way as abdominal swabs. AD - C.M. Marsden, Surgical Division, Q. A. Military Hosp. Horley, Surrey, United Kingdom AU - Marsden, C. M. DB - Embase Classic IS - 1 KW - furosemide arthrography cartilage clip cyst diagnosis foreign body histiocytoma hospital knee knee meniscus knee meniscus rupture lacrimal fluid sitting xanthoma LA - English M3 - Article N1 - L280505294 1947-12-01 PY - 1947 SN - 0035-8665 SP - 29-37 ST - An analysis of 100 consecutive operations on the knee and a report on a xanthoma of the knee-joint T2 - Journal of the Royal Army Medical Corps TI - An analysis of 100 consecutive operations on the knee and a report on a xanthoma of the knee-joint UR - https://www.embase.com/search/results?subaction=viewrecord&id=L280505294&from=export VL - 89 ID - 698 ER - TY - JOUR AB - A 36 year old female with cerebellar ataxia and severe lumbothoracic scoliosis presented with uncontrolled hypertension, epistaxis and difficult venous access at 26 week gestation. She had a HELLP syndrome with raised ALT, low platlets count (32) and required stabilization and urgent caesarean section. She had modified RSI with propofol and rocuronium and given a transversus abdominus plane block. She showed significant weakness on emergence, although respiratory function was adequate. The baby weight was 425gm and required further management in SCBU. There was a persistence of raised ALT in postoperative period although platelet count improved to normal levels following surgery. Discussion: 1. The complex spinal surgery excluded any neuraxial block 2. The presence of Cerebellar ataxia, muscular hypotonia and severe preeclampsia lead to a careful choice of anaesthetic and neuromuscular block. In her case, we were able to safely perform RSI without suxamethonium. 3. Attenuation of the hypertensive response to intubation must be achieved in cases of severe pre-eclampsia. The BP control was achieved with MgSO4, labetalol intravenously and remifentanil infusion. 4. She also had a difficult venous access. The venous access was gained using ultrasound and then a central line was inserted. 5. The severe thrombocytopenia at her operation raised concerns with increased bleeding tendency. Also performance of TAP block was risky as any concealed bleeding could manifest later on in recovery. She had a normal clotting screen. The surgical team confirmed adequate clotting at her operation and TAP block was performed safely at end of her operation. AD - A. Kapoor, Anaesthetics, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom AU - Kapoor, A. AU - Jones, S. AU - Wight, W. DB - Embase DO - 10.1097/AAP.0b013e31826a8366 IS - 5 KW - anesthetic agent rocuronium propofol labetalol remifentanil suxamethonium human cerebellar ataxia HELLP syndrome spine surgery intrauterine growth retardation preeclampsia scoliosis patient society regional anesthesia female hypertension cesarean section intubation attenuation thrombocytopenia bleeding tendency bleeding weakness pregnancy epistaxis neuromuscular blocking muscle hypotonia surgery platelet count postoperative period weight baby infusion ultrasound respiratory function LA - English M3 - Conference Abstract N1 - L70881020 2012-10-01 PY - 2012 SN - 1098-7339 SP - E247-E248 ST - Anaesthetic management of a patient with cerebellar ataxia, scoliosis and spinal surgery (Harrington Rods) complicated by severe preeclampsia (Hellp Syndrome) with fetal growth retardation T2 - Regional Anesthesia and Pain Medicine TI - Anaesthetic management of a patient with cerebellar ataxia, scoliosis and spinal surgery (Harrington Rods) complicated by severe preeclampsia (Hellp Syndrome) with fetal growth retardation UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70881020&from=export http://dx.doi.org/10.1097/AAP.0b013e31826a8366 VL - 37 ID - 509 ER - TY - JOUR AB - An underlying tenet of design in the biologic realm is that the optimal design of the prosthetic device reproduces exactly the healthy, intact biologic situation in every case (geometric, kinetic). Because the optimal solution is unobtainable, however, because of the limited resources available, compromises must be made. Every compromise inevitably produces complications because of the interdependent nature of biologic systems. The goal then becomes to minimize the detrimental effects of the implant system through the best possible use of the technologies available. It is the author's experience that whenever this fundamental tenet is forgotten in the design of an implant, either the system is affected adversely, or unforeseen complications arise in an associated system. An example can be seen in the evolution of solutions to the problem of loosening of the femoral component of hip prostheses. This loosening is caused, in part, by improper load transmission to the femur. Until recently, most hip implants transferred stress to the femur distally through the stem of the implant. Because of the lack of physiologic stress levels in the proximal femur bone, resorption was common, which often led to loosening of the implant. Many current designs are able to provide proximal loading of the femur through well-designed, proximal press fits. Although this seems to be a better solution, these prostheses fall short of the biologic situation in that they impose hoop stress to bone cells that naturally experience primarily axial stresses. The subsequent remodeling of bone because of the change in the load direction may not provide adequate stability for the implant in the long-term. In the same way, a best effort must be made in the present design to maintain near-physiologic load transfer and motion. Therefore, considerable effort was invested in the design stage of this project to consider the solutions available today to duplicate the stiffness (flexibility) of the lumbar disc in its principal plane of motion. This philosophy of restoration of function was also applied in specifying the geometry and the constraints to motion imposed by the prosthesis. The long life span required of an artificial spinal disc poses a significant challenge to the design effort. Plastics available today cannot be counted on to last for 40 years and 100 million cycles. The proposition of 40 years of metal-on-metal, however, was somewhat alarming. Therefore, quantitative wear-simulation testing has accompanied this development project since the second year of the project. Likewise, other factors, such as fatigue stress and corrosion resistance, become increasingly important because of the extended life span of the device. Therefore, as part of this project, standard material fatigue experiments (such as rotating bend tests) have been performed on the hot isostatatically pressed cobalt-chromium and titanium couples. The loads in the quadruped lumbar spine are largely in shear, which is in contrast to the more upright human lumbar spine, in which the loads are mainly in compression. The fact that bone ingrowth occurred in these animals under the worst-case scenario (shear loads) is most encouraging. There was no foreign body reaction in regional tissues and lymph nodes other than a mild fibrous tissue later over the implant. No soft tissue ingrowth was seen histologically in the springs. Although small numbers of animals were analyzed, the results were encouraging and would suggest that human implementation is feasible with little or no likelihood of mechanical failure, loosening, or disaster. A categoric list of design criteria relevant to the development of an articulating spinal disc implant has been presented. Each of these criteria and many of the questions posed are relevant in the synthesis of any new implant system. Constraints imposed by an implant have been discussed at length. A method of constraint analysis that simplifies specification of motion constraints has been described. Specifications of the preclinical trial design of an interver ebral disc prosthesis have been listed and evaluated on the basis of some of the pretrial experimental data. This design is the product of the detailed prospective design technique that has been the focus of this article. It is a design that will undergo future revisions based on clinical trial data, yet the implant's limitations and its in vitro performance has been assessed thoroughly during the past years to minimize the number of revisions necessary because of unsatisfactory results in clinical trials. AD - J.P. Kostuik, Department of Orthopaedic Surgery, Johns Hopkins University, 601 North Caroline Street, Baltimore, MD 21287-0882, United States AU - Kostuik, J. P. DB - Embase Medline DO - 10.1016/S0030-5898(05)70042-0 IS - 4 KW - biocompatibility biomechanics bone prosthesis geometry human intervertebral disk intervertebral disk hernia discectomy ischialgia priority journal review spine fusion surgical technique LA - English M3 - Review N1 - L28501133 1998-11-26 PY - 1998 SN - 0030-5898 SP - 701-715 ST - Alternatives to spinal fusion T2 - Orthopedic Clinics of North America TI - Alternatives to spinal fusion UR - https://www.embase.com/search/results?subaction=viewrecord&id=L28501133&from=export http://dx.doi.org/10.1016/S0030-5898(05)70042-0 VL - 29 ID - 658 ER - TY - JOUR AB - Allergy to Prolene suture is exceedingly rare with only 5 cases reported in the literature. There have been no such cases associated with neurosurgical procedures. Diagnosis is nearly always delayed in spite of persistent symptomatology. A 27-year-old girl with suspected Ehlers-Danlos, connective tissue disorder, underwent posterior fossa decompression for Chiari Type 1 malformation. One year later, the patient presented with urticarial rash from the neck to chest. Cerebrospinal fluid and blood testing, magnetic resonance imaging, and intraoperative exploration did not suggest allergic reaction. Eventually skin testing proved specific Prolene allergy. After suture material was removed, the patient no longer complained of pruritus or rash. This single case highlights the important entity of allergic reaction to suture material, namely, Prolene, which can present in a delayed basis. Symptomatology can be vague but has typical allergic characteristics. Multidisciplinary approach is helpful with confirmatory skin testing as a vital part of the workup. © 2015 Iahn Cajigas et al. AD - Department of Neurological Surgery and the Miami Project to Cure Paralysis, University of Miami, Miller School of Medicine, Miami, FL 33136, United States Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, University of Miami, Miller School of Medicine, Miami, FL 33136, United States Division of Gastroenterology, University of Miami, Miller School of Medicine, Miami, FL 33136, United States AU - Cajigas, I. AU - Burks, S. S. AU - Gernsback, J. AU - Fine, L. AU - Moshiree, B. AU - Levi, A. D. C7 - 583570 DB - Scopus DO - 10.1155/2015/583570 M3 - Article N1 - Cited By :2 Export Date: 10 November 2020 PY - 2015 ST - Allergy to prolene sutures in a dural graft for chiari decompression T2 - Case Reports in Medicine TI - Allergy to prolene sutures in a dural graft for chiari decompression UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85032618220&doi=10.1155%2f2015%2f583570&partnerID=40&md5=d5ab3c181899c60beedbbc131074aa17 VL - 2015 ID - 1245 ER - TY - JOUR AB - Introduction: Sarcoidosis is the great mimic. It has so many presentations that it becomes easy to label everything as Sarcoid. This is one such case where appearances were deceiving on many levels. HPI: This is a case of a previously health 33 y/o African American male who presented to the pulmonary service because of Tachycardia, and Hypoxia with an SaO2 of 90% on room air. Past History: No previous medical history of significance; no surgical history; denied drug, alcohol and tobacco abuse. He used to work in the demolition of houses, including burnt and old houses. A Chest X-Ray was ordered and showed classical bilateral hilar lymphadenopathy. A CTA of the chest was ordered at the time to rule out a pulmonary embolism as well. There was no PE, however Adenopathy was confirmed. Diagnoses including Sarcoidosis, Lymphoma, and Fungal Disease were entertained at that time. To this end, various labs were ordered of which the significant ones were as follows: Fungal serologies negative; CBC normal except for differential showing a eosinophil count of 10.7%; LDH 223; Negative autoimmune workup; Serum ACE level at 119 (normal 8.0 - 52.0); Protein Electrophoresis showing elevated levels of IgG, Kappa chains, and Lambda chains; All tumor markers were negative. Bronchoscopy done which showed a lymphocyte count of 74% with all cultures negative, including negative fungal smear. Transbronchial biopsies taken came back showing no evidence for malignancy but positive for foreign body granulomas. Suspicion for Sarcoidosis was strong until that point but with this new evidence it seemed possible that he was abusing IV drugs either in addition to Sarcoid or separately. The patient however denied this despite several different physicians trying several approaches. His wife confirmed that he never had done drugs. Electron microscopy and spectroscopy of the foreign bodies was then done which showed them to be consistent with Talc silicates. At this point it was felt that the likelihood was occupational exposure to silicates/talc during his years in demolition. Discussion: African American, Hilar Adenopathy, Elevated ACE levels, Granulomas, and no significant medical history. Although this is classical for Sarcoidosis we should always be aware of reliability of the various tests we order even when all point in the same direction. Specifically we should be aware of inhalational Talcosis without necessarily being exposed to IV drugs is an entity which can and does mimic sarcoidosis, despite our classical association of Talc with IV drugs. AD - J. Taji, University of Toledo Medical Center, Toledo, OH, United States AU - Taji, J. AU - Goyal, R. AU - Mattar, Z. AU - Assaly, R. DB - Embase IS - 1 KW - talc alcohol tumor marker immunoglobulin kappa chain silicate lactate dehydrogenase sarcoidosis society human lymphadenopathy African American medical history lung embolism lymphocyte count transbronchial biopsy ambient air male thorax protein electrophoresis hypoxia thorax radiography eosinophil count granuloma serum tachycardia serology bronchoscopy mycosis smear foreign body granuloma patient lymphoma physician tobacco dependence foreign body spectroscopy diagnosis electron microscopy occupational exposure health reliability inhalational drug administration LA - English M3 - Conference Abstract N1 - L70841949 2012-08-27 PY - 2010 SN - 1073-449X ST - All that's hilar is not sarcoid T2 - American Journal of Respiratory and Critical Care Medicine TI - All that's hilar is not sarcoid UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70841949&from=export http://ajrccm.atsjournals.org/cgi/reprint/181/1_MeetingAbstracts/A4499?sid=3bc2b9c9-3093-4521-a7ed-d2a0457f612a VL - 181 ID - 567 ER - TY - JOUR AN - 105916589. Language: English. Entry Date: 20080104. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Blind Peer Reviewed DB - ccm DP - EBSCOhost IS - 1 KW - Hospitals Patient Safety Computers, Hand-Held Drug Information Electronic Order Entry Organizational Culture Personnel Staffing and Scheduling Pneumonia, Ventilator-Associated -- Prevention and Control Software Surgical Count Procedure N1 - Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 8913099. PY - 2007 SN - 1046-7394 SP - 25-25 ST - AHRQ issues patient safety tips for hospitals T2 - South Carolina Nurse TI - AHRQ issues patient safety tips for hospitals UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105916589&site=ehost-live&scope=site VL - 14 ID - 932 ER - TY - JOUR AB - The article focuses on the resolution of operating room (OR) discrepancies in the U.S. Topics discussed include the guidelines of the Association of periOperative Registered Nurses (AORN) for item retention, the provisions of the guidelines, and the significance of accounting the missing items in OR. AN - 113709219. Language: English. Entry Date: 20160316. Revision Date: 20160322. Publication Type: Article DB - ccm DP - EBSCOhost IS - 4 KW - Surgical Count Procedure -- Standards Operating Room Personnel Retained Instruments Hospital Policies N1 - brief item. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Perioperative Care. NLM UID: 7810150. PY - 2016 SN - 0190-5066 SP - 41-41 ST - Advice on resolving count discrepancies in the OR...second part of a two part series T2 - Same-Day Surgery TI - Advice on resolving count discrepancies in the OR...second part of a two part series UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=113709219&site=ehost-live&scope=site VL - 40 ID - 806 ER - TY - JOUR AN - 107037250. Language: English. Entry Date: 20050507. Revision Date: 20150711. Publication Type: Journal Article AU - Carolan, J. DB - ccm DP - EBSCOhost IS - 6 KW - Hospital Policies Perioperative Nursing Professional Compliance Surgical Count Procedure Surgical Sponges Medical Orders N1 - brief item; questions and answers. Journal Subset: Nursing; Peer Reviewed; USA. NLM UID: 20010080R. PY - 2001 SN - 0033-7021 SP - 73-73 ST - Advice of counsel. Heed hospital policy on sponge counts, not the surgeon T2 - RN TI - Advice of counsel. Heed hospital policy on sponge counts, not the surgeon UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107037250&site=ehost-live&scope=site VL - 64 ID - 889 ER - TY - JOUR AB - Adverse reaction to wear and corrosion debris is a cause for concern in total hip arthroplasty (THA). Modular junctions are a potential source of such wear products and are associated with secondary pseudotumour formation. We present a consecutive series of 17 patients treated at our unit for this complication following metal-on-highly cross-linked polyethylene (MoP) THA. We emphasise the risk of misdiagnosis as infection, and present the aggregate laboratory results and pathological findings in this series. The clinical presentation was pain, swelling or instability. Solid, cystic and mixed softtissue lesions were noted on imaging and confirmed intra-operatively. Corrosion at the head-neck junction was noted in all cases. No bacteria were isolated on multiple pre- and intra-operative samples yet the mean erythrocyte sedimentation rate was 49 (9 to 100) and C-reactive protein 32 (0.6 to 106) and stromal polymorphonuclear cell counts were noted in nine cases. Adverse soft-tissue reactions can occur in MoP THA owing to corrosion products released from the head-neck junction. The diagnosis should be carefully considered when investigating pain after THA. This may avoid the misdiagnosis of periprosthetic infection with an unidentified organism and mitigate the unnecessary management of these cases with complete single- or two-stage exchange. © 2015 The British Editorial Society of Bone & Joint Surgery. AD - Trauma and Orthopaedics, Musculoskeletal Research Unit, University of Bristol, Bristol, BS10 5NB, United Kingdom Kyushu University Hospital, 3-1-1, Maidashi, Higashi-ku, Fukuoka City, 812-8582, Japan Pathology and Laboratory Medicine, Anatomical Pathology Vancouver General Hospital, 855 W 12th Ave, Vancouver, V5Z 1M9, Canada University of British Columbia, 910 West 10th Avenue, Vancouver, BC V5Z 4E3, Canada AU - Whitehouse, M. R. AU - Endo, M. AU - Zachara, S. AU - Nielsen, T. O. AU - Greidanus, N. V. AU - Masri, B. A. AU - Garbuz, D. S. AU - Duncan, C. P. DB - Scopus DO - 10.1302/0301-620X.97B8.34682 IS - 8 M3 - Article N1 - Cited By :82 Export Date: 10 November 2020 PY - 2015 SP - 1024-1030 ST - Adverse local tissue reactions in metal-onpolyethylene total hip arthroplasty due to trunnion corrosion: The risk of misdiagnosis T2 - Bone and Joint Journal TI - Adverse local tissue reactions in metal-onpolyethylene total hip arthroplasty due to trunnion corrosion: The risk of misdiagnosis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84938386870&doi=10.1302%2f0301-620X.97B8.34682&partnerID=40&md5=4f127e9c3013e18e45ad5006272990ee VL - 97-B ID - 1223 ER - TY - JOUR AB - This article describes the process of root cause analysis (RCA), the theories of error that underlie the concept of systemic or latent factors that allow errors to occur or to be propagated without correction; the difference between the process in health care and those found in high-reliability organizations; and suggests some ways to augment the standard health care RCA into a more robust and helpful process. © 2012 Elsevier Inc. AD - Department of Surgery, University of South Florida, FL, United States Surgical Safety Institute, 4951 West Bay Drive, Tampa, FL 33629, United States AU - Karl, R. AU - Karl, M. C. DB - Scopus DO - 10.1016/j.suc.2011.12.003 IS - 1 KW - Latent factors Root cause analysis Systemic factors Theories of error M3 - Review N1 - Cited By :11 Export Date: 10 November 2020 PY - 2012 SP - 89-100 ST - Adverse Events: Root Causes and Latent Factors T2 - Surgical Clinics of North America TI - Adverse Events: Root Causes and Latent Factors UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84856156976&doi=10.1016%2fj.suc.2011.12.003&partnerID=40&md5=a529347628786c03b5dd988347e2a40d VL - 92 ID - 1384 ER - TY - JOUR AB - The adhesion of neutrophils onto different vascular grafts was studied in vivo in a pig model. In acute experiments autologous 111In-labelled neutrophils were reinfused after end-to-side implantation of 5cm, 6mm internal diameter grafts. The dynamic deposition on each graft was determined for 300min in vivo. Static measurements in vitro concluded the study. The adhesion was greater in Dacron and collagen coated Dacron grafts compared to expanded polytetrafluoroethylene (ePTFE) and to Dacron grafts coated with a polymer. The segmental activity along all the grafts increased towards the distal anastomosis. The results suggest different inflammatory response to various graft materials. © 1993 Grune & Stratton Ltd. AD - Department of Surgery, Lund University, Sweden AU - Pärsson, H. AU - Jundzill, W. AU - Jonung, T. AU - Thörne, J. AU - Norgren, L. DB - Scopus DO - 10.1016/S0950-821X(05)80006-4 IS - 3 KW - Inflammatory reaction Neutrophils Vascular grafts M3 - Article N1 - Cited By :17 Export Date: 10 November 2020 PY - 1993 SP - 257-262 ST - The adhesion of labelled neutrophils on synthetic vascular grafts. An experimental porcine study T2 - European Journal of Vascular Surgery TI - The adhesion of labelled neutrophils on synthetic vascular grafts. An experimental porcine study UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027221505&doi=10.1016%2fS0950-821X%2805%2980006-4&partnerID=40&md5=e816ca0e4a7199822a6a478f996d2980 VL - 7 ID - 1732 ER - TY - JOUR AB - Adenovirus (AdV) infections in transplant recipients may cause invasive disease. We present a case of granulomatous interstitial nephritis secondary to AdV infection in a renal transplant recipient that was initially interpreted as acute graft rejection on histopathology. Specific testing based on clinical suspicion, however, aided in making an accurate diagnosis. We present a retrospective review of all cases of AdV infection in renal transplant recipients to date, and analyze outcomes based on different treatment modalities for this disease. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd AD - Department of Internal Medicine, Allegheny General Hospital, Pittsburgh, PA, United States Division of Infectious Disease, Allegheny General Hospital, Pittsburgh, PA, United States AU - Veer, M. AU - Abdulmassih, R. AU - Como, J. AU - Min, Z. AU - Bhanot, N. C7 - e12716 DB - Scopus DO - 10.1111/tid.12716 IS - 4 KW - adenovirus nephritis rejection transplantation M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2017 ST - Adenoviral nephritis in a renal transplant recipient: Case report and literature review T2 - Transplant Infectious Disease TI - Adenoviral nephritis in a renal transplant recipient: Case report and literature review UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85024373445&doi=10.1111%2ftid.12716&partnerID=40&md5=73c393d5d972c8849b9ed5e44a077a9e VL - 19 ID - 1128 ER - TY - JOUR AB - Acute scrotal pain should be treated as a condition that requires immediate medical attention. Herein, we report the case of a 60-year-old male who sought emergency medical care for acute scrotal pain of 2-day duration. Results of an imaging examination revealed an abscess in the scrotum and the presence of foreign bodies in the urethra. The abscess was incised and drained, and the foreign bodies were removed from the urethra. Antibiotic therapy was initiated, and the patient was relieved of scrotal pain. He was discharged from hospital in a stable condition 10 days after the surgery. © 2013, Taiwan Surgical Association. AD - Division of Urology, Department of Surgery, Taiwan Landseed Hospital, Ping-jen City, Tao-Yuan County, Taiwan AU - Liao, W. S. AU - Shen, B. Y. AU - Wu, C. C. DB - Scopus DO - 10.1016/j.fjs.2013.03.002 IS - 3 KW - Acute scrotal pain Urethral foreign bodies M3 - Article N1 - Export Date: 10 November 2020 PY - 2013 SP - 97-99 ST - Acute scrotal pain associated with urethral foreign bodies T2 - Formosan Journal of Surgery TI - Acute scrotal pain associated with urethral foreign bodies UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84891343575&doi=10.1016%2fj.fjs.2013.03.002&partnerID=40&md5=467484742bfd9a19afe519735330a21f VL - 46 ID - 1338 ER - TY - JOUR AB - Background: Choledocholithiasis is an endemic condition in the world. Although rare, foreign body migration with biliary complications needs to be considered in the differential diagnosis for patients presenting with typical symptoms even many years after cholecystectomy, EPCP, war-wound, foreign body ingestion or any other particular history before. It is of great clinical value as the present review may offer some help when dealing with choledocholithiasis caused by foreign bodies. Case presentation: We reported a case of choledocholithiasis caused by fishbone from choledochoduodenal anastomosis regurgitation. Moreover, we showed up all the instances of choledocholithiasis caused by foreign bodies published until June 2018 and wrote the world's first literature review of foreign bodies in the bile duct of 144 cases. The findings from this case suggest that the migration of fishbone can cause various consequences, one of these, as we reported here, is as a core of gallstone and a cause of choledocholithiasis. Conclusion: The literature review declared the choledocholithiasis caused by foreign bodies prefer the wrinkly and mainly comes from three parts: Postoperative complications, foreign body ingestion, and post-war complications such as bullet injury and shrapnel wound. The Jonckheere-Terpstra test indicated the ERCP was currently the treatment of choice. It is a very singular case of choledocholithiasis caused by fishbone, and the present review is the first one concerning choledocholithiasis caused by foreign bodies all over the world. © 2019 The Author(s). AD - Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou,Guangdong, 510080, China Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, 510000, China Department of Internal Medicine, Peking Union Medical College Hospital, Beijing, 100730, China AU - Yu, M. AU - Huang, B. AU - Lin, Y. AU - Nie, Y. AU - Zhou, Z. AU - Liu, S. AU - Hou, B. C7 - 177 DB - Scopus DO - 10.1186/s12876-019-1088-8 IS - 1 KW - Choledocholithiasis Common bile duct Fishbone Foreign body M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2019 ST - Acute obstructive cholangitis due to fishbone in the common bile duct: A case report and review of the literature T2 - BMC Gastroenterology TI - Acute obstructive cholangitis due to fishbone in the common bile duct: A case report and review of the literature UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074693599&doi=10.1186%2fs12876-019-1088-8&partnerID=40&md5=f9199f7b55c5e88ca52d01df780bf8fa VL - 19 ID - 992 ER - TY - JOUR AB - Background: Coronary intervention is related to local vascular and systemic inflammation that leads to the stimulation of inflammatory reaction, caused by the rupture of the atherosclerotic plaque and the tunica media fallowing extension of the stent and insertion of a metallic foreign body. Arterial wall damage occurs in addition to the release of inflammatory and chemoattractant factors which stimulate an inflammatory response, leading to leukocyte and platelet activation. Bioresorbable vascular Scaffold (BVS) is considered the fourth revolution in interventional cardiology. It has introduced a novel technology in the treatment of coronary artery disease (CAD). Trimetazidine (TMZ) is an anti-ischemic agent which minimizes the myocardial damage induced by the percutaneous coronary intervention (PCI). Objective: To assess the effect of TMZ on the acute inflammatory response after BVS implantation in patients with CAD. Patients and Methods: A total of 40 diabetic patients with stable coronary artery disease were assigned into two groups: the control group and TMZ treated group. Both groups were admitted to AL-Najaf center for cardiac surgery and Tran’s catheter therapy. Thus, patients under went elective coronary scaffold implantation. Serum blood was collected from peripheral vein before implantation, 12 hrs and 24 hrs after implantation. Collected samples were used to measure IL-8, hs-CRP, cTn-I, MMP-9 and VCAM-1 levels by sand wichELISA method in addition to determine the WBC count. Results. Scaffold implantation produced significant changes in serum levelIL-8, hs-CRP, cTn-I, WBC and VCAM-1(p<0.05).However, no significant change in serum level MMP-9was found (p>0.05).On the other hand, TMZ treatment produced a significant decrease in cTn-I, hs-CRP levels and the WBC count (p<0.05).No significant changes in serum IL-8, MMP-9and VCAM-1were found (p>0.05). Conclusion: Trimetazidine reduced the systemic inflammatory response induced by implantation of Bioresorbable coronary scaffold. AD - N.R. Hadi, Department of Pharmacology & Therapeutics, Faculty of Medicine, University of Kufa, Iraq AU - Alsalkhi, H. A. AU - Rajeeb, A. N. AU - Ahmed, M. H. AU - Hadi, N. R. AU - Amber, K. I. AU - Muhammad-Baqir, B. M. DB - Embase DO - 10.31838/ijpr/2020.SP2.348 KW - adult article bioresorbable vascular stent catheter clinical article controlled study coronary artery disease diabetic patient drug therapy female gene expression heart muscle injury heart surgery human human tissue implantation inflammation leukocyte count male percutaneous coronary intervention peripheral vein protein expression surgery C reactive protein endogenous compound interleukin 8 trimetazidine vascular cell adhesion molecule 1 LA - English M3 - Article N1 - L2005220200 2020-10-26 PY - 2020 SN - 0975-2366 SP - 1966-1973 ST - Acute inflammatory response after bioresorbable coronary scaffold implantation and impact of trimetazidine T2 - International Journal of Pharmaceutical Research TI - Acute inflammatory response after bioresorbable coronary scaffold implantation and impact of trimetazidine UR - https://www.embase.com/search/results?subaction=viewrecord&id=L2005220200&from=export http://dx.doi.org/10.31838/ijpr/2020.SP2.348 VL - 12 ID - 273 ER - TY - JOUR AB - Purpose: Nonspecific inflammatory reactions characterized by local tenderness, fever, and flu-like discomfort have been seen in patients undergoing endoluminal graft placement in the abdominal aorta or the femoral arteries. We undertook a study to assess the clinical and laboratory parameters of this inflammation. Methods: Ten patients with femoropopliteal artery (n = 9) or aortic (n = 1) lesions were treated with EndoPro System 1 stent-grafts made of nitinol alloy and covered with a polyester (Dacron) fabric. Eleven patients implanted with a bare nitinol stent served as the control group. Results: In the stent-graft group, four patients showed clinical signs of acute inflammation manifested by fever and local tenderness. Three of these patients suffered thrombosis of the stent-grafts during the first month of follow-up. Plasma levels of interleukin-1β and interleukin-6 in all stent-graft patients were markedly increased 1 day after intervention (7.3 ± 2.8 versus 90.2 ± 34.1 pg/mL and 15.6 ± 5.8 versus 175.5 ± 66.3 pg/mL, respectively; p < 0.01). This was followed by an increase in fibrinogen (3.0 ± 0.2 versus 5.0 ± 0.2 g/L; p < 0.05) and C- reactive protein (14.6 ± 3.3 versus 77.5 ± 15.0 mg/L, p < 0.01) at 1 week. No direct correlation between the inflammatory markers and symptoms could be found. In vitro analysis showed that individual components of the stent- graft did not activate human neutrophils, whereas the intact stent-graft itself induced a marked neutrophil activation. Conclusions: The component of the self-expanding stent-graft responsible for the nonspecific inflammatory reaction was not identified in this study. It is likely that the stent-graft itself or some as yet unrecognized element of the device other than the Dacron fabric or metal alloy may be a potent in vivo inducer of cytokine reaction by neutrophils. AD - Division of Vascular Medicine, CHUV, 1011 Lausanne, Switzerland AU - Hayoz, D. AU - Do, D. D. AU - Mahler, F. AU - Triller, J. AU - Spertini, F. AU - Veith, F. J. DB - Scopus DO - 10.1583/1074-6218(1997)004<0354:AIRAWE>2.0.CO;2 IS - 4 KW - Cytokines Dacron graft material EndoPro System 1 Nitinol stents Stent-grafts M3 - Article N1 - Cited By :29 Export Date: 10 November 2020 PY - 1997 SP - 354-361 ST - Acute inflammatory reaction associated with endoluminal bypass grafts T2 - Journal of Endovascular Surgery TI - Acute inflammatory reaction associated with endoluminal bypass grafts UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031439230&doi=10.1583%2f1074-6218%281997%29004%3c0354%3aAIRAWE%3e2.0.CO%3b2&partnerID=40&md5=ff7772957cf868af8cddaea13fad19bf VL - 4 ID - 1703 ER - TY - JOUR AB - A case is presented of a rectosigmoid foreign body causing perforation of the rectosigmoid colon and ulcerating the base of the appendix that resulted in acute appendicitis in a 9-year-old boy, which was initially misdiagnosed. A preoperative diagnosis of acute appendicitis was made after clinical evaluation and abdominal ultrasound, suggestive of the same. An upright abdominal X-ray was also performed to rule out suspected perforation, which showed a radio-opaque shadow in the right iliac region, misdiagnosed as a fecalith. The abdomen was opened for appendectomy and the tip of a pen was immediately observed perforating the sigmoid colon, touching the base of the appendix and ulcerating it, resulting in appendicitis. Subsequently, the pen was removed from the perforation site. Sigmoid colon perforation was repaired and appendectomy was performed. There were no postoperative complications, and the patient was referred for psychiatric evaluation. Histopathology of the specimen confirmed acute appendicitis. © 2014. AD - Resident Pediatric Surgery, Department of Pediatric Surgery, SPMCHI, Sawai Man Singh Hospital, Jaipur, India Postgraduate Department of Surgery, Acharya Shri Chander College of Medical Sciences, Hospital Jammu (Jammu and oKashmir), Jammu, India Medical Officer, Jaipur, India AU - Gupta, R. AU - Mala, T. A. AU - Gupta, A. AU - Gupta, A. K. AU - Paul, R. DB - Scopus DO - 10.1016/j.fjs.2014.05.004 IS - 5 KW - Acute appendicitis Foreign body Pen Perforation Rectosigmoid M3 - Article N1 - Export Date: 10 November 2020 PY - 2014 SP - 204-206 ST - Acute appendicitis resulting from rectosigmoid foreign body T2 - Formosan Journal of Surgery TI - Acute appendicitis resulting from rectosigmoid foreign body UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028170924&doi=10.1016%2fj.fjs.2014.05.004&partnerID=40&md5=29c1317cdb8b91919911e8a24a33a6d3 VL - 47 ID - 1257 ER - TY - JOUR AB - Peritonitis is inflammation of the peritoneum and represents an important cause of surgical morbidity and mortality. It may be localized or generalized, and is thought to pass through three phases: firstly, a phase of rapid removal of contaminants from the peritoneal cavity into the systemic circulation; secondly, a phase of synergistic interactions between aerobes and anaerobes; and thirdly, an attempt by host defences to localize infection. Peritonitis is commonly caused by bacteria, but can be chemical (aseptic), biliary, tuberculous, chlamydial, drug-induced or induced by other, rarer causes. Bacterial peritonitis is subclassified into primary or secondary on the basis of whether or not the integrity of the gastrointestinal tract has been compromised. Typically, the patient with peritonitis complains of severe abdominal pain and may exhibit the characteristic Hippocratic facies. Abdominal palpation demonstrates tenderness, guarding and rebound tenderness. Initial laboratory investigations should include urea and electrolytes, full blood count and blood gases. An erect radiograph of the chest demonstrates pneumoperitoneum in about 70-80% of visceral perforations. CT often plays a role in confirming specific diagnoses (e.g. subphrenic abscess). Immediate management should include fluid resuscitation, high-flow oxygen, appropriate antibiotics (i.v.) and analgesia. Definitive management is surgical except for a small group of patients in whom conservative management with fluids (i.v.) and antibiotics (i.v.) is indicated. Surgical management can be via a laparotomy or, in some conditions, laparoscopy. Control of the primary site of sepsis is the main determinant of outcome. Most patients recover quickly. However, major generalized peritonitis is associated with organ dysfunction/failure, and mortality can up to 20-40% in the UK. © 2008 Elsevier Ltd. All rights reserved. AD - R.J.E. Skipworth, Edinburgh Royal Infirmary, Edinburgh, United Kingdom AU - Skipworth, R. J. E. AU - Fearon, K. C. H. DB - Embase DO - 10.1016/j.mpsur.2008.01.004 IS - 3 KW - amylase antibiotic agent antiemetic agent antifungal agent antineoplastic agent cephalosporin electrolyte isoniazid meropenem metronidazole opiate oxygen piperacillin plus tazobactam practolol urea abdominal abscess abdominal drainage abdominal pain abdominal tenderness acute abdomen adhesion amebiasis amylase blood level analgesia antibiotic therapy aspiration aspiration pneumonia bacterial peritonitis biliary peritonitis blood cell count blood gas analysis chlamydiasis clinical feature computer assisted tomography conservative treatment differential diagnosis disease classification disease severity drug withdrawal emergency surgery familial Mediterranean fever fluid resuscitation foreign body human hyperlipidemia intensive care laboratory test laparoscopic surgery laparotomy lead poisoning liver function test nasogastric tube oxygen therapy pancreas juice pathogenesis pathophysiology patient positioning peritonitis pneumoperitoneum porphyria priority journal prognosis review risk reduction scoring system sepsis septic shock Streptococcus pneumoniae thorax radiography treatment response tuberculous peritonitis urea blood level LA - English M3 - Review N1 - L351459375 2008-04-22 PY - 2008 SN - 0263-9319 SP - 98-101 ST - Acute abdomen: peritonitis T2 - Surgery TI - Acute abdomen: peritonitis UR - https://www.embase.com/search/results?subaction=viewrecord&id=L351459375&from=export http://dx.doi.org/10.1016/j.mpsur.2008.01.004 VL - 26 ID - 602 ER - TY - JOUR AB - Objective: We aimed to present a patient with acute abdominal pain secondary to small bowel perforation caused by fish bone penetration through the jejunal wall. Case: A 52-year-old man presented to the emergency department with a 3-day history of abdominal pain. He had no nausea, vomiting or diarrhea. The abdominal examination revealed diffuse tenderness and muscle guarding. The plain abdominal X ray showed free subdiaphragmatic air. His laboratory results revealed an elevated white blood cell count (11,700 with 78 % neutrophils) and normal serum amylase (43 U/L). The presumptive diagnosis was peptic ulcer perforation and the patient underwent diagnostic laparoscopy. Laparoscopy showed several inflamed, edematous jejunal loops with a foreign body causing through and through perforation of the jejunum and protruding from the two opposite wall on the anti-mesenteric side. It also caused impaction and obstruction at the same level and could not be removed. Intracorporeal resection and anastomosis with a laparoscopic linear stapler, which was inserted through two small enterotomies approximately 5 cm proximal and distal to the stricture site, was performed using a 15, a 10 and a 5 mm trocar. The segment of resected bowel was removed through the 15 mm trocar site. The postoperative period was uneventful, and the patient was discharged on the fourth day. Conclusion: Through and through perforation and obstruction of small bowel is a unique presentation of fish bone. In the current case it caused acute abdominal symptoms and free subdiaphragmatic air on the plain abdominal X ray and was managed laparoscopically. AD - A.C. Dural, Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey AU - Dural, A. C. AU - Yigitbas, H. AU - Dogan, M. AU - Kankaya, B. AU - Kones, O. AU - Celik, M. F. AU - Akarsu, C. AU - Dogan, Y. AU - Alis, H. DB - Embase DO - 10.1007/s00464-014-3484-z KW - small intestine intestine perforation fish bone surgery anastomosis endoscopic surgery acute abdomen human patient abdominal radiography perforation diagnosis trocar obstruction laparoscopy laboratory laryngeal mask muscle examination implantable cardioverter defibrillator leukocyte count intestine diarrhea stapler jejunum vomiting ulcer perforation nausea foreign body amylase blood level neutrophil postoperative period abdominal pain emergency ward male LA - English M3 - Conference Abstract N1 - L71478627 2014-06-04 PY - 2014 SN - 0930-2794 SP - S87 ST - Acute abdomen caused by through and through small bowel perforation due to clinically unsuspected fish bone: Laparoscopic resection and anastomosis T2 - Surgical Endoscopy and Other Interventional Techniques TI - Acute abdomen caused by through and through small bowel perforation due to clinically unsuspected fish bone: Laparoscopic resection and anastomosis UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71478627&from=export http://dx.doi.org/10.1007/s00464-014-3484-z VL - 28 ID - 450 ER - TY - JOUR AB - Background: Acupuncture and dry needling are increasingly popular treatment modalities used to treat pain around the world. This case report documents the clinical history of a patient who presented to an outpatient physical therapy clinic following surgical removal of two single-use filament needles that fractured in the patient's neck during acupuncture treatment. Case Description: The purpose of this case report was to highlight a rare adverse event following acupuncture treatment. The patient received the acupuncture treatment from a practitioner licensed in acupuncture, while on an international business trip. Following the acupuncture treatment, the practitioner realized that a needle had fractured and remained in the patient's neck. After failing to retrieve the needle, the patient was sent for imaging. Radiograph revealed that the patient had two needle fragments located in his cervical tissue. After determining that the needles did not pose an immediate threat, the patient boarded a flight home to the United States. Following his flight, the patient presented to an American hospital where it was discovered that the needle fragments had migrated during the flight, with one needle now located 2 mm from the patient's vertebral artery. Surgical intervention was required to retrieve the needles, resulting in the patient needing physical therapy to increase cervical range of motion and mediate pain relief. Outcomes: The patient suffered a setback in his treatment of chronic neck pain that resulted in decreased cervical range of motion and increased pain. Discussion: Clinicians utilizing single-use filiform needles in their practice, whether for acupuncture or dry needling, should be aware of the potential for this type of adverse event. Further, to minimize the risk of similar adverse events occurring in the future, clinicians should make sure that they are using high quality needles and make a habit of counting in and counting out the needles that they use to verify that all needles are accounted for. AD - a Youngstown State University , Youngstown , OH , USA. AN - 31023177 AU - Snyder, D. D. C2 - PMC6598534 DA - Jul DO - 10.1080/10669817.2019.1608010 DP - NLM ET - 2019/04/27 IS - 3 KW - *Acupuncture Therapy/adverse effects/instrumentation *Dry Needling/adverse effects Foreign Bodies/*surgery Humans Male Middle Aged Needles/*adverse effects Acupuncture acupuncturist adverse events chronic neck pain complications dry needling filiform needles physical therapy LA - eng N1 - 2042-6186 Snyder, Drew D Case Reports Journal Article J Man Manip Ther. 2019 Jul;27(3):180-184. doi: 10.1080/10669817.2019.1608010. Epub 2019 Apr 25. PY - 2019 SN - 1066-9817 (Print) 1066-9817 SP - 180-184 ST - Acupuncture gone awry: a case report of a patient who required surgical removal of two single-use filament needles following acupuncture treatment T2 - J Man Manip Ther TI - Acupuncture gone awry: a case report of a patient who required surgical removal of two single-use filament needles following acupuncture treatment VL - 27 ID - 230 ER - TY - JOUR AB - Fixed DC was compared to ceftriaxone, ceftriaxone with 200 μA fixed DC, or no treatment in a rat model of methicillin-susceptible Staphylococcus aureus foreign-body osteomyelitis. After 3 weeks, fewer bacteria were present in bones of the ceftriaxone group (5.71 log 10 cfu/g [P = 0.0004]) and the ceftriaxone/DC group (3.53 log 10 cfu/g [P = 0.0002]) than untreated controls (6.70 log 10 cfu/g). Fewer bacteria were present in the ceftriaxone/DC group than in the ceftriaxone-alone and DC-alone groups (P = 0.0012 and 0.0008, respectively). There were also fewer bacteria on the implanted wires in the groups treated with ceftriaxone (5.47 log 10 cfu/cm 2 ) or ceftriaxone/DC (2.82 log 10 cfu/cm 2 ) than in the untreated controls (6.44 log 10 cfu/cm 2 [P = 0.0003 and 0.0002, respectively]). There were fewer bacteria in the ceftriaxone/DC rats than in the ceftriaxone-alone– and fixed DC-alone–treated rats (P = 0.0017 and 0.0016, respectively). Fixed DC with an antibiotic may be useful for treating foreign-body infections caused by S. aureus. © 2018 Elsevier Inc. AD - Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, United States Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, United States Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, MN 55905, United States AU - Schmidt-Malan, S. M. AU - Brinkman, C. L. AU - Greenwood-Quaintance, K. E. AU - Karau, M. J. AU - Mandrekar, J. N. AU - Patel, R. DB - Scopus DO - 10.1016/j.diagmicrobio.2018.09.006 IS - 2 KW - Prosthetic joint infection Staphylococcus aureus Treatment M3 - Article N1 - Export Date: 10 November 2020 PY - 2019 SP - 92-95 ST - Activity of fixed direct electrical current in experimental Staphylococcus aureus foreign-body osteomyelitis T2 - Diagnostic Microbiology and Infectious Disease TI - Activity of fixed direct electrical current in experimental Staphylococcus aureus foreign-body osteomyelitis UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054352604&doi=10.1016%2fj.diagmicrobio.2018.09.006&partnerID=40&md5=20abc8ae27cfcc541c1005d2b3ad4a14 VL - 93 ID - 1023 ER - TY - JOUR AB - Prolyl hydroxylase activity in rat and rabbit sponge induced granulation tissue was studied as a function of time after implantation. The method of expression of such data was critical in determination of the shape of the curve. The method of data expression used in this paper was, cpm/μg of fibrocyte and fibroblast (F-DNA) or cpm per μg hydroxyproline. Use of other parameters such as extractable protein, wet weight or total DNA changed the shape of the curve and obscured the rapid increases in prolyl hydroxylase activity occurring during the first 48 hours. Giemsa and fast green staining was found to be a useful method for identification of fibroblasts in tissue sections. The use of this stain facilitated the large number of differential counts necessary for the calculation of F-DNA from total DNA values. Rats were treated with cyclophosphamide or antineutrophil serum to deplete them of neutrophils and monocytes. Such treatment failed to inhibit the usual increase in prolyl hydroxylase occurring in granulation tissue by the third day. In the rabbit an early 2-3 fold increase in prolyl hydroxylase activity in vivo was observed four hours after sponge implantation. This early increase in activity was blocked by inhibitors of RNA and protein synthesis and was considered to be dependent on new protein synthesis rather than on activation of a proenzyme. © 1977 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. AD - Department of Medicine, Research Laboratories Long Island Jewish-Hillside Medical Center, New Hyde Park, NY, 11040, United States Clinical Campus Stony Brook Medical School, SUNY, United States AU - Wiener, S. L. AU - Urivetzky, M. AU - Isenberg, H. D. AU - Belenko, M. AU - Talansky, A. AU - Havier, R. AU - Meilman, E. DB - Scopus DO - 10.3109/03008207709152236 IS - 2 M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 1977 SP - 97-108 ST - Activation of prolyl hydroxylase in sponge induced granulation tissue: The effect of antineutrophil serum and inhibitor drugs T2 - Connective Tissue Research TI - Activation of prolyl hydroxylase in sponge induced granulation tissue: The effect of antineutrophil serum and inhibitor drugs UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-0017713490&doi=10.3109%2f03008207709152236&partnerID=40&md5=0b02bff5c70001a2cffdf15298aed2d3 VL - 5 ID - 1770 ER - TY - JOUR AB - Introduction: Mechanical circulatory support using an implanted ventricular assist device (VAD) is an important means of enhancing or maintaining the quality of life for heart failure patients awaiting heart transplant (bridge to transplant), during the recovery of their own heart (bridge to recovery) or for long-term destination therapy (no transplant). The non-physiologic continuous blood flow of a VAD (CF-VAD) exposes blood and vasculature to abnormal shear stress and leads to a variety of hemostatic derangements that likely contribute to the development of bleeding complications, neurologic dysfunction and venous thromboembolism in these patients. Additionally, the implanted CF-VAD likely stimulates the body's natural innate immune response to a foreign object. We hypothesize that the continuous activation of platelets due to the non-physiologic blood flow and the foreign nature of the CF-VAD combine to stimulate an immune response. Previous studies have suggested thatanti- PF4/heparin antibodies [as targeted in a diagnosis of heparin-induced thrombocytopenia (HIT)] can develop in the absence of heparin. It is believed that these antibodies are not related to heparin per se but rather are generated as a physiological response by platelets, in their capacity to generate an innate immune response, reacting to non-self substances. This study evaluated the time course of anti- PF4/heparin titers in patients supported by CF-VADs. Methods: Blood samples were collected from 13 randomly selected patients prior to implantation of a HeartMate II CF-VAD and at routine clinic visits following implantation. Median follow-up was 183 days (range: 32-352 days). Anti-PF4/heparin antibody titers were determined by the PF4 Enhanced X-45 Assay (Immucor GTI Diagnostics, Waukesha, WI). Patients were treated with heparin at the time of implant; long-term anticoagulation was maintained with warfarin (INR 1.5-2.0) and low-dose aspirin. Results: Following CF-VAD implantation, there was an acute increase in median platelet count from 169,000 to 420,000/μl. With increasing time post-implant, the median platelet count returned to preimplant levels; no patients became thrombocytopenic. Pre-implant, 6 of 13 patients had 'positive' anti- PF4/heparin titers (OD >0.4 using the HIT criteria); the median OD for all patients was 0.433. There was a progressive increase in median titer with increasing time post-implant. At 1 month the median OD was 0.54. By 2 months all patients had an OD >0.4 with a median value of 0.82 (>0.750 is high clinical thrombosis risk using the HIT criteria). The median OD continued to rise through 8 months postimplant. At 5 months and later OD values >1.5 were common. OD values >1.5 were present in some patients as early as 1 month post-implant. Discussion: The mechanism(s) associated with CF-VAD pump thrombosis and other adverse events remains unclear. The above data shows that long-term implant of a CF-VAD leads to the development of anti-PF4/heparin antibodies. Such a response may result from shear-induced platelet activation and subsequent release of PF4. This response is similar to a previous report in which patients who underwent total knee or hip arthroplasty and subsequently received dynamic mechanical thromboprophylaxis demonstrated an anti-PF4/heparin immune response even in the absence of heparin (Bito et al, Blood 2016). CF-VAD-related infection may also contribute to the generation of anti-PF4/heparin antibodies as PF4 bound to bacteria has previously been shown to induce antibody formation (Krauel et al, Blood 2011). Data from our lab has shown that patients with implanted CFVADs are frequently in heightened states of inflammation (ASH 2016 abstract) with excessive levels of C-reactive protein in patients who develop pump thrombosis. CRP has been shown to activate platelets and accelerate thrombogenesis (Xu et al, BMC Immunology 2015). Thus, it is plausible that the development of anti-PF4/heparin antibodies may be an indicator of an early activation mechanism of adverse events in CF-VAD implanted patients hrough the cross-talk between the hemostatic and immune systems. Larger studies are required to determine whether the presence of such antibodies confers any risk to LVAD patients. The presence of anti-PF4/heparin antibodies may be of particular concern for LVAD patients undergoing a subsequent surgery for pump replacement or heart transplant. AD - W. Jeske AU - Jeske, W. AU - Walenga, J. M. AU - Torres, T. AU - Escalante, V. AU - Schwartz, J. AU - Bakhos, M. DB - Embase IS - 22 KW - acetylsalicylic acid antibody biological marker C reactive protein endogenous compound heparin thrombocyte factor 4 warfarin adverse device effect adverse drug reaction animal model antibody production antibody titer anticoagulation blood flow chemical binding clinical article clinical trial device infection diagnosis drug therapy follow up gene expression heart graft heparin induced thrombocytopenia hip arthroplasty hospital human human cell human tissue immunology implant inflammation innate immunity international normalized ratio knee left ventricular assist device low drug dose side effect surgery thrombocyte activation platelet count thrombosis LA - English M3 - Conference Abstract N1 - L614265880 2017-02-06 PY - 2016 SN - 1528-0020 ST - Activated immune response in ventricular assist device implanted patients identified through a platelet activation biomarker T2 - Blood TI - Activated immune response in ventricular assist device implanted patients identified through a platelet activation biomarker UR - https://www.embase.com/search/results?subaction=viewrecord&id=L614265880&from=export VL - 128 ID - 386 ER - TY - JOUR AN - 105677349. Language: English. Entry Date: 20081031. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Australia & New Zealand DA - 2008 Winter DB - ccm DP - EBSCOhost IS - 2 KW - Perioperative Nursing Australian College of Operating Room Nurses Cesarean Section Congresses and Conferences Female Obesity, Morbid -- In Pregnancy Perioperative Nursing -- Education Pregnancy Queensland Surgical Count Procedure Treatment Errors -- Prevention and Control Wrong Site Surgery -- Prevention and Control N1 - Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. PY - 2008 SN - 1448-7535 SP - 35-38 ST - ACORN 13th National Conference: Between the Flags, 21-24 May 2008, Gold Coast, QLD: abstracts T2 - ACORN: The Journal of Perioperative Nursing in Australia TI - ACORN 13th National Conference: Between the Flags, 21-24 May 2008, Gold Coast, QLD: abstracts UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105677349&site=ehost-live&scope=site VL - 21 ID - 884 ER - TY - JOUR AB - Clot formation within membrane oxygenators (MOs) remains a critical problem during extracorporeal membrane oxygenation (ECMO). The composition of the clots—in particular, the presence of von Willebrand factor (vWF)—may be an indicator for prevalent nonphysiological flow conditions, foreign body reactions, or coagulation abnormalities in critically ill patients. Mats of interwoven gas exchange fibers from randomly collected MOs (PLS, Maquet, Rastatt, Germany) of 21 patients were stained with antibodies (anti-vWF and anti-P-selectin) and counterstained with 4′,6-diamidino-2-phenylindole. The extent of vWF-loading was correlated with patient and technical data. While 12 MOs showed low vWF-loadings, 9 MOs showed high vWF-loading with highest accumulations close to crossing points of adjacent gas fibers. The presence and the extent of vWF-fibers/“cobwebs,” leukocytes, platelet–leukocyte aggregates (PLAs), and P-selectin-positive platelet aggregates were independent of the extent of vWF-loading. However, the highly loaded MOs were obtained from patients with a significantly elevated SOFA score, severe thrombocytopenia, and persistent liver dysfunction. The coagulation abnormalities of these critically ill patients may cause an accumulation of the highly thrombogenic and elongated high-molecular-weight vWF multimers in the plasma which will be trapped in the MOs during the ECMO therapy. © 2019 The Authors. Artificial Organs published by Wiley Periodicals, Inc. on behalf of International Center for Artificial Organ and Transplantation (ICAOT) AD - Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany Department of Internal Medicine II, University Medical Center Regensburg, Regensburg, Germany Department of Anesthesiology, University Medical Center Regensburg, Regensburg, Germany Regensburg Center of Biomedical Engineering, Ostbayerische Technische Hochschule, Regensburg, Germany AU - Steiger, T. AU - Foltan, M. AU - Philipp, A. AU - Mueller, T. AU - Gruber, M. AU - Bredthauer, A. AU - Krenkel, L. AU - Birkenmaier, C. AU - Lehle, K. DB - Scopus DO - 10.1111/aor.13513 IS - 11 KW - extracorporeal membrane oxygenation liver dysfunction shear stress SOFA score thrombogenesis von Willebrand factor M3 - Article N1 - Cited By :6 Export Date: 10 November 2020 PY - 2019 SP - 1065-1076 ST - Accumulations of von Willebrand factor within ECMO oxygenators: Potential indicator of coagulation abnormalities in critically ill patients? T2 - Artificial Organs TI - Accumulations of von Willebrand factor within ECMO oxygenators: Potential indicator of coagulation abnormalities in critically ill patients? UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074673840&doi=10.1111%2faor.13513&partnerID=40&md5=2a95ef09af6d3fad9ae59dd3d045640f VL - 43 ID - 993 ER - TY - JOUR AN - 107928524. Language: English. Entry Date: 20140110. Revision Date: 20150820. Publication Type: Journal Article DB - ccm DP - EBSCOhost IS - 1 KW - Surgical Count Procedure -- Standards Joint Commission -- Standards Sentinel Event -- Prevention and Control Retained Instruments -- Risk Factors Retained Instruments -- Prevention and Control Surgical Instruments Surgical Patients N1 - brief item. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Special Interest: Patient Safety; Perioperative Care. NLM UID: 7600137. PY - 2014 SN - 0360-4039 SP - 24-24 ST - Accounting for surgical items left behind T2 - Nursing TI - Accounting for surgical items left behind UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107928524&site=ehost-live&scope=site VL - 44 ID - 892 ER - TY - JOUR AB - Background: Agave species has previously been reported to cause both vesicopapular and purpuric dermatitis. Causative agents are believed to be steroidal saponins and calcium oxalate crystals in agave sap. Aseptic inflammatory arthritis has been reported from foreign bodies such as thorns or cactus needles after inadvertent arthrotomy; however, this has not been described from agave plants. Hypothesis: Agave sap irritants may cause an aseptic inflammatory arthritis mimicking a septic arthritis. Methods: This is a single patient chart review. A 27-year-old male presented with malaise, left knee pain, swelling, and inability to range his knee 2 hours after suffering an accidental stab wound to his left lateral knee by an agave plant spine. The patient had no history of intravenous drug use, sexually transmitted infections, or current genitourinary complaints. Workup included complete blood count, basic metabolic panel, ESR, CRP, lactate, blood cultures, gonorrhea/chlamydia testing, synovial fluid studies, and surgical washout. Results: The patient remained afebrile with normal vital signs.WBC was 14 (1000/mm3), ESR was 2 mm/h, CRP was 2.2 mg/dL, and lactate was 2.6 mmol/L. The remainder of his CBC and BMP was within normal limits. Synovial fluid WBC was 92,730 (1000/mm3) with 75% neutrophils and no crystals. Gram stain was negative. After repeating synovial fluid testing, orthopedics took the patient for a washout remarkable for turbid fluid and no foreign bodies. Synovial fluid and blood cultures remained without growth. Antibiotics were stopped on POD 1 and the patient was discharged from the orthopedic service. At 2 weeks follow-up, he is doing well. Conclusion: Agave sap toxicity may contribute to aseptic inflammatory arthritis seen acutely in the emergency department. AD - S.T. Ontiveros, University of California San Diego, San Diego, CA, United States AU - Ontiveros, S. T. AU - Minns, A. B. DB - Embase DO - 10.1007/s13181-020-00759-7 IS - 2 KW - antibiotic agent irritant agent lactic acid adult adverse drug reaction Agave arthrotomy bacterial arthritis bacterium culture blood cell count blood culture case report Chlamydia clinical article conference abstract drug therapy emergency ward follow up foreign body gonorrhea Gram staining hospital discharge human human cell knee pain malaise male medical record review monarthritis neutrophil nonhuman orthopedics plant spine side effect stab wound swelling synovial fluid vital sign LA - English M3 - Conference Abstract N1 - L631721540 2020-05-18 PY - 2020 SN - 1937-6995 SP - 161-162 ST - Accidental arthrotomy causing aseptic monoarthritis due to agave sap T2 - Journal of Medical Toxicology TI - Accidental arthrotomy causing aseptic monoarthritis due to agave sap UR - https://www.embase.com/search/results?subaction=viewrecord&id=L631721540&from=export http://dx.doi.org/10.1007/s13181-020-00759-7 VL - 16 ID - 299 ER - TY - JOUR AD - Director, Faculty Center for Excellence in Teaching (FaCET), University of Missouri-Kansas City; Associate Professor, School of Nursing, University of Missouri, Kansas City, MO AN - 104182925. Language: English. Entry Date: 20130624. Revision Date: 20200708. Publication Type: Journal Article AU - Ward-Smith, Peggy DB - ccm DO - 10.7257/1053-816X.2013.33.3.148 DP - EBSCOhost IS - 3 KW - Urologic Nursing Kidney Transplantation Living Donors Neoplasms Surgical Count Procedure Surgical Sponges Retained Instruments -- Risk Factors Disease Surveillance Urinary Catheterization Urinary Tract Infections Catheter-Related Infections Information Seeking Behavior Decision Making, Patient Prostatic Neoplasms -- Therapy Female Male N1 - abstract. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 8812256. PY - 2013 SN - 1053-816X SP - 148-150 ST - Abstracts T2 - Urologic Nursing TI - Abstracts UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104182925&site=ehost-live&scope=site VL - 33 ID - 769 ER - TY - JOUR AB - BACKGROUND: Surgical site infections following spinal surgery, including spinal abscesses, are rare but serious as they are major causes of morbidity, and even mortality. They are, however, rarely attributed to infected, retained surgical cottonoids or sponges (textiloma or gossypiboma) inadvertently left in an operative field. CASE DESCRIPTION: A 53-year-old female with a history of two prior spinal operations at the L4-S1 levels (11 and 2 years previously) presented over a few weeks with the acute onset of a cauda equina syndrome (e.g., paraparesis and acute urinary incontinence). The patient demonstrated a mildly elevated white blood cell count (12,600/mm(3)) and abnormally increased C-reactive protein level that correlated with the magnetic resonance imaging that showed a dorsal epidural abscess extending from the L4 to S1 levels. At surgery, an encapsulated posterior epidural abscess was drained. Surgical findings included a granulomatous lesion consistent with a retained surgical cottonoid and was removed from the antero-inferior portion of the abscess wall at S1. Culture of the thick fibrotic abscess wall grew Klebsiella oxytoca. After 2 months of ciprofloxacin, the patient's infection cleared but the motor deficit only partially resolved. CONCLUSION: Most spinal textilomas (gossypibomas) are aseptic and are found in paraspinal areas without neurological symptoms or sequelae. These lesions may remain silent for years and may only rarely cause neurologic or infectious symptoms/signs. Notably, textilomas following spinal surgery may be largely avoided if proper cottonoid and sponge counts are done prior to closing spinal wounds. AD - Department of Neurosurgery, Avicenne Military Hospital of Marrakech, Mohammed V University in Rabat, Rabat, Morocco. Department of Histopathology, Avicenne Military Hospital of Marrakech, Mohammed V University in Rabat, Rabat, Morocco. AN - 29721349 AU - Akhaddar, A. AU - Baallal, H. AU - Elktaibi, A. C2 - PMC5909092 DO - 10.4103/sni.sni_64_18 DP - NLM ET - 2018/05/04 KW - Cauda equina syndrome gossypiboma retained cottonoid spinal epidural abscess surgical complication surgical site infection textiloma LA - eng N1 - 2152-7806 Akhaddar, Ali Baallal, Hassan Elktaibi, Abderrahim Case Reports Surg Neurol Int. 2018 Apr 5;9:70. doi: 10.4103/sni.sni_64_18. eCollection 2018. PY - 2018 SN - 2229-5097 (Print) 2152-7806 SP - 70 ST - Abscess due to textiloma (gossypiboma: Retained surgical cottonoid) T2 - Surg Neurol Int TI - Abscess due to textiloma (gossypiboma: Retained surgical cottonoid) VL - 9 ID - 212 ER - TY - CASE A4 - Yang, Hyung-Seok A2 - Shin, Jae A2 - Yang, John A2 - Choi, Jae-Cheol A2 - Park, Tae A2 - Lee, Ja A2 - Kim, Hye A2 - Lee, Jeong A2 - Oh, Seung A2 - Shin, Jae Gyun A2 - Yang, John Jeongseok A2 - Park, Tae Sung A2 - Lee, Ja Young A2 - Kim, Hye Ran A2 - Lee, Jeong Nyeo A2 - Oh, Seung Hwan AB - The article presents a case study of a 30-year-old female who was taken to the hospital for surgery for foreign-body removal in the abdomen due to decline count of red blood cells. It mentions that patient has denied history of prior transfusion or transplantation, and states that genotype-phenotype discrepancy in the patient was unexplainable, possibilities of analytical errors. It also mentions that ABO discrepancies in cell typing due to the presence of mixed-field RBC agglutination. AD - Department of Laboratory Medicine, School of Medicine , Kyung Hee University , 23, Kyungheedae-ro, Dongdaemun-gu Seoul 02454 Republic of Korea Department of Laboratory Medicine , Inje University College of Medicine , 75, Bokji-ro, Busanjin-gu Busan 47392 Republic of Korea Department of Laboratory Medicine , Hanmaeum Hospital , 21 Woni-daero, 682 Beon-gil, Seongsan-gu Changwon 51497 Republic of Korea Department of Laboratory Medicine, Inje University College of Medicine, 75, Bokji-ro, Busanjin-gu, Busan, 47392, Republic of Korea Department of Laboratory Medicine, School of Medicine, Kyung Hee University, 23, Kyungheedae-ro, Dongdaemun-gu, Seoul, 02454, Republic of Korea DB - ccm DO - 10.1007/s00277-017-3048-0 DP - EBSCOhost J2 - Annals of Hematology KW - Electrophoresis Blood Grouping and Crossmatching Chimerism ABO Blood-Group System Phenotype Female Sequence Analysis Genotype Mutation Heterozygote Adult DNA N1 - Accession Number: 124395611. Language: English. Entry Date: 20170902. Revision Date: 20181116. Publication Type: case study; letter. Journal Subset: Biomedical; Continental Europe; Europe. NLM UID: 9107334. PMID: NLM28634615. NV -, PB - Springer Nature PY - 2017 SP - 1583-1585 ST - ABO genotype-phenotype discrepancy due to chimerism resolved by clonal separation TI - ABO genotype-phenotype discrepancy due to chimerism resolved by clonal separation UR - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=124395611&site=ehost-live&scope=site VL - 96 ID - 754 ER - TY - JOUR AB - Background: Abnormal uterine bleeding in adolescence is caused by multiple factors, being the most frequent anovulatory dysfunctional uterine bleeding (DUB), coagulopathies, pregnacy complications and infections. Pelvic infection due to Actinomices has been described in long term IUD users, or other foreign bodies, in which infection is ascendent. Less frequently it is secondary to an appendectomy. Common symptoms are abdominal pain, pelvic tumor, uterine bleeding or fever. These kind of infections are extremely rare in adolescence. Case: 12-year old girl, carrier of a mild Von Willebrand disease, presents with repeated metrorrhagia since menarche, up to 20 days. No history of abuse or sexual initiation was present. Due to poor response to tranexamic acid, oral contraceptives pills (OCP) were initiated. Patient presented with a new episode of bleeding during OCP use, with no response to tranexamic acid, OCP in high doses (up to 90 etinylestradiol mcg a day), and only temporary response to desmopresin. Disabling pelvic pain and purulent vaginal discharge without fever was added. Initial blood count showed 19000 leukocytes and 22 ERS. Vaginal culture: normal flora, Chlamydia and Gonococco NAATs were negative. Pelvic ultrasound (Figure 1) revealed a significant increase in uterine volume (11.5 x 5.3 cm length) and cavity occupied by an image resembling a clot, measuring 6 x 2.5 cm. An hysteroscopy was performed, showing fibrinolitic, purulent material. Curettage culture was positive for Actinomyces spp. (MALDI-TOF MS) and biopsy findings were compatible with the diagnosis. An MRI performed post curettage (Figure 2), showed no abdominal or pelvic collections, nor tumoral images. Patient is currently in her third month of antibiotic treatment and was cycled succesfully with progestagens. The bleeding had a total duration of 2 months, ceased 25 days after curettage and abdominal pain subsided after 2 months of antibiotic treatment, with progressive normalization of uterine volume. Comments: Causes for AUB in adolescence may be multiple and combined. This is how our patient presents a coagulopathy, anovulatory cycles and finally an infection was added. Chlamydial and gonococal endometritis might present with abnormal heavy bleeding, associated with pelvic pain in adolescents. Actinomices endometritis is not a common diagnosis, especially in the absence of a foreign body. In this case we hypothesize that an intracavitary organized clot might have acted as a foreign body, allowing Actinomices to ascend from a dilated cervix. Actinomices, an anaerobic bacteria, is hard to culture, and diagnosis is frecuently done with anatomopathological findings. Treatment with antibiotics is prolonged, 3 to 12 months, being Betalactams the first choice. This case emphasizes that every time a patient presents with non responsive AUB, rare causes should be ruled out. (Figure Presented). AD - M. Menéndez, División De Obstetricia y Ginecología, Pontificia Universidad Católica De Chile, Santiago, Chile AU - Menéndez, M. AU - Zajer, C. AU - Ralph, C. AU - Canessa, M. J. AU - Zuñiga, P. AU - Vizcaya, C. DB - Embase DO - 10.1016/j.jpag.2016.01.084 IS - 2 KW - tranexamic acid ethinylestradiol oral contraceptive agent antibiotic agent human adolescent gynecology endometritis uterus bleeding clinical research North American society female infection patient curettage foreign body adolescence diagnosis bleeding abdominal pain pelvic pain fever metrorrhagia antibiotic therapy uterus pelvis von Willebrand disease leukocyte girl blood cell count vagina discharge drug megadose pelvis tumor pelvic inflammatory disease appendectomy flora anaerobic bacterium anovulation abuse menarche blood clotting disorder biopsy Actinomyces hysteroscopy ultrasound Chlamydia pill nuclear magnetic resonance imaging intrauterine contraceptive device LA - English M3 - Conference Abstract N1 - L72228938 2016-04-13 PY - 2016 SN - 1083-3188 SP - 193-194 ST - Abnormal uterine bleeding asociated to actinomices endometritis in perimenarcheal adolescent T2 - Journal of Pediatric and Adolescent Gynecology TI - Abnormal uterine bleeding asociated to actinomices endometritis in perimenarcheal adolescent UR - https://www.embase.com/search/results?subaction=viewrecord&id=L72228938&from=export http://dx.doi.org/10.1016/j.jpag.2016.01.084 VL - 29 ID - 406 ER - TY - JOUR AB - RATIONALE: Foreign bodies are frequently ingested, but only approximately 1% of them cause perforation. Perforations in the lesser curvature of the stomach are exceedingly rare. Here, we report a case of gastric perforation in the lesser curvature caused by a foreign body. The patient presented to the clinic complaining of abdominal skin swelling and reddening with upper abdominal discomfort as the initial symptoms. PATIENT CONCERNS: An 83-year-old female presented with a mass in the middle of the epigastrium for 10 days. Physical examination found an apparent local tenderness and inflammatory mass in the upper abdominal wall. Her body temperature was normal (37.5°C) and the white blood cell count was elevated (8.12 × 10/L [reference value 3.5-9.5 × 10/L]). DIAGNOSES: The ultrasound examination of the abdomen revealed a 4 cm strip-like hyperechoic object entangled in the muscles of the abdominal wall. The computed tomography scan revealed a thin strip of bone-like hyperdense shadow. Intraoperative findings showed a sharp fishbone protruding from the lesser curvature of the stomach into the abdominal cavity, part of which remained in the gastric cavity. The postoperative pathological report revealed chronic suppurative inflammation with abscess and sinus canal formation. INTERVENTIONS & OUTCOMES: The patient underwent a gastric foreign body removal with partial gastrectomy. Anti-inflammatory treatment post-surgery rapidly relieved the patient's symptoms of discomfort in the upper abdomen. At the 1-month follow-up, the patient showed no discomfort in the upper abdomen and the inflammatory mass was no longer present. LESSONS: A foreign body had penetrated through the lesser curvature of the stomach, an area with a flat gastric wall, which occurs infrequently. In such cases, computed tomography is the gold standard for diagnosis of foreign bodies in the digestive tract. Ultrasound can also be used as a supplemental diagnostic technique. It is recommended that people who wear dentures should exercise caution while eating, especially when the food contains bones. AD - Department of Ultrasound Diagnosis, The First Hospital of Jilin University, China. AN - 33019459 AU - Zhang, L. AU - Liu, L. AU - Shao, J. AU - Sun, F. AU - Zhao, L. C2 - PMC7535683 authors have no conflicts of interest to disclose. DA - Oct 2 DO - 10.1097/md.0000000000022534 DP - NLM ET - 2020/10/07 IS - 40 KW - Abdominal Wall/*pathology Aftercare Aged, 80 and over Bone and Bones Eating Female Foreign Bodies/diagnostic imaging/*surgery Humans Inflammation/*etiology Seafood Skin/*pathology Spontaneous Perforation Stomach/microbiology/pathology/*surgery Tomography, X-Ray Computed/methods Treatment Outcome Ultrasonography/methods LA - eng N1 - 1536-5964 Zhang, Lili Liu, Lifang Shao, Jiangbo Sun, Fangfang Zhao, Lirong Case Reports Journal Article Medicine (Baltimore). 2020 Oct 2;99(40):e22534. doi: 10.1097/MD.0000000000022534. PY - 2020 SN - 0025-7974 (Print) 0025-7974 SP - e22534 ST - Abdominal skin inflammation as an initial symptom of a perforating gastric foreign body: A case report T2 - Medicine (Baltimore) TI - Abdominal skin inflammation as an initial symptom of a perforating gastric foreign body: A case report VL - 99 ID - 263 ER - TY - JOUR AB - A 75-year-old man with diabetic end-stage renal disease requiring hemodialysis presented with one week of progressive abdominal pain and fevers. Laboratory examination showed an alkaline phosphatase of 140 IU/L and white blood cell count of 15.7 x 109. Non-contrast abdominal computed tomography revealed a 2.9 x 3.3 cm air/fluid collection in the left hepatic lobe with a linear foreign body extending from the collection into the duodenum. An upper endoscopy was performed and was notable for two pustular lesions and edema in the second portion of the duodenum. He was referred to our center for further evaluation and management as an outpatient. On endoscopic ultrasound, a loculated fluid collection within the left hepatic lobe was seen. After transduodenal puncture and contrast injection, a linear foreign body could be seen radiographically within the cavity. A 0.025 inch by 450 cm long guidewire was passed into the cavity and a through-the-scope 6 mm balloon dilator was used to dilated the tract. A 4 cm by 10 mm fully covered self-expandable metal stent was placed into the cavity for abscess drainage and to allow a fistula to form in order to endoscopically retrieve the object. The patient was discharged to home from the procedure suite on oral antibiotics and returned 4 weeks later for repeat endoscopy. The indwelling stents were removed and the tract was dilated with a through-the-scope anastomotic balloon dilator up to 15 mm. The gastroscope was advanced into the cavity. Utilizing a grasping device, a segment of wood was gripped and retrieved. After removal, it was confirmed that the foreign object was a toothpick, but had not been removed intact so a snare was used to grasp the remaining portion of the object for complete retrieval. The patient remained outpatient without the need for hospitalization during our care as there were no procedure-related adverse events. Foreign bodies in the liver are rare and are typically related to surgery or trauma. This patient reported frequently chewing toothpicks, one of which likely was inadvertently ingested and lodged in the duodenum before eventually eroding into the liver. As with all infections, prompt recognition, administration of antibiotics and source control are critical for managing foreign bodies in the liver parenchyma. EUS-guided abscess drainage followed by endoscopic retrieval is a feasible non-surgical option in some cases of intrahepatic foreign bodies. AU - James, T. AU - Baron, T. H. DB - Embase DO - 10.1016/j.gie.2020.03.637 IS - 6 KW - alkaline phosphatase antibiotic agent endogenous compound abdominal pain abscess drainage aged balloon case report clinical article computer assisted tomography conference abstract diabetes mellitus duodenum edema end stage renal disease endoscopic ultrasonography endoscopy fever fistula foreign body gastroscope guide wire hemodialysis hospital discharge hospitalization human human tissue information retrieval laboratory test left liver lobe leukocyte count liver parenchyma male mastication outpatient puncture self expandable metallic stent LA - English M3 - Conference Abstract N1 - L2006054222 2020-06-05 PY - 2020 SN - 1097-6779 0016-5107 SP - AB87 ST - 976 YOU CAN'T ALWAYS PICK YOUR PATIENTS: EUS-GUIDED TRANSHEPATIC REMOVAL OF AN EMBEDDED TOOTHPICK T2 - Gastrointestinal Endoscopy TI - 976 YOU CAN'T ALWAYS PICK YOUR PATIENTS: EUS-GUIDED TRANSHEPATIC REMOVAL OF AN EMBEDDED TOOTHPICK UR - https://www.embase.com/search/results?subaction=viewrecord&id=L2006054222&from=export http://dx.doi.org/10.1016/j.gie.2020.03.637 VL - 91 ID - 276 ER - TY - JOUR AB - A 31-year-old woman underwent99mTc-labeled UBI scanning for diagnosis of possible prosthesis infection evaluation in our department. The scan showed an area of increased tracer uptake in the mid-lateral portion of the left thigh. This was proven to be due to a retained surgical gauze in her left thigh. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. AD - Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran AU - Ghahremani, S. AU - Sadeghi, R. AU - Kakhki, V. R. D. AU - Massoudi, T. AU - Aryana, K. DB - Scopus DO - 10.1097/RLU.0000000000001389 IS - 12 KW - Foreign body Hip Scintigraphy UBI Ubiquicidin M3 - Article N1 - Cited By :1 Export Date: 10 November 2020 PY - 2016 SP - 941-943 ST - 99mTc-Labeled ubiquicidin accumulation in a retained surgical gauze T2 - Clinical Nuclear Medicine TI - 99mTc-Labeled ubiquicidin accumulation in a retained surgical gauze UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021850012&doi=10.1097%2fRLU.0000000000001389&partnerID=40&md5=7a47fc2c47a4e012a4a326ebb2c860e5 VL - 41 ID - 1166 ER - TY - JOUR AB - A 61-year-old male, a company staff for 30 years and on leave for 2 years, presented to the pulmonary department with one week of moderate fever and nonproductive cough. The physical examination showed temperature of 37.5 °C, heart rate of 90 beats/minute, respiratory rate of 20 breaths/minute and BP if 150/90 mmHg. The findings of his cardiac examination were normal. Pulmonary examination revealed decreases tactile fremitus, dullness and decreased breath sound at right lower lobe. No rales could be heard throughout both lung fields. The results of remainder of the examinations were unremarkable. Admission laboratory results showed elevated WBC count (10400/ll) with a normal differential, an increased C reactive protein level (108 mg/l), partial arterial oxygen pressure (PO2) of 78 mmHg, the carbon dioxide pressure (POC2) of 32 mmHg, and PH 7.45. The forced vital capacity was 2.16 l (62.8% of predicted) and the forced expiratory volume in 1 second (FEV1) was 1.97 l (72.8% of predicted). A chest computerized tomography (CT) showed consolidation and atelectasis if the right lower lobe and obstruction of the right intermediate bronchus at the level of right pulmonary artery (Figure 1). Multiplanar and three-dimensional (3D) imaging of the central airway demonstrated a spherical foreign body in the right intermediate bronchus (Figure 2). In autofluorescence bronchoscopy, a mobile, pedunculated, and pinkish polypoid tumor protruding from the right lower lobe bronchus was observed. No invasion of bronchial wall was detected. As it was difficult to get through the bronchus, we performed an inferior bronchoscopy high-frequency electrosurgical snare resection. The pathological examination revealed that the specimen was a 15×25 mm ellipsoid covered by normal ciliated pseudostratified columnar epithelium and stratified squamous epithelium. The polyps consisted of fibrovascular stroma with scattered lymphocytes, plasma cells and vessels. Diagnosis: Fibroepithelial polyp of the bronchus. Tumors in the tracheobronchial tree are distinctly uncommon and account for 0.1-0.4% of malignant diseases. After the review of literature, we found the morbidity of this polyp was still uncertain. Ans over the past few decades, about 21 patients with tracheobronchial fibroepithelial polyp were reported. Only 10 case reports are available for analysis. To our knowledge, this is the first report in china population. Although the pathogenesis of fibroepithelial polyp is still unresolved, chronic inflammatory processes may play a key role. Several chronic inflammatory etiologic factors such as chronic smoke inhalation, chronic inflammation of asthma and COPD, repeated airway infections, foreign body aspiration, and prolonged mechanical ventilation may potentially be the cause. AD - M. Li, Department of Respiratory Medicine, People's Hospital of Shanghai, Shanghai, China AU - Li, M. DB - Embase DO - 10.1111/j.1400-1843.2011.02071.x KW - C reactive protein society human Asian male pneumonia bronchus polyp examination neoplasm bronchoscopy forced vital capacity forced expiratory volume thorax computer assisted tomography obstruction pulmonary artery imaging airway atelectasis autofluorescence surgery columnar epithelium squamous epithelium foreign body lymphocyte plasma cell stroma diagnosis tracheobronchial tree morbidity patient China pathogenesis inflammation etiology smoke case report inhalation chronic inflammation asthma respiratory tract infection foreign body aspiration population fever coughing physical examination temperature heart rate breathing rate abnormal respiratory sound lung laboratory leukocyte count arterial oxygen tension carbon dioxide tension pH artificial ventilation LA - English M3 - Conference Abstract N1 - L70576610 2011-11-16 PY - 2011 SN - 1323-7799 SP - 276 ST - A 61-year-old man with recurrent pneumonia T2 - Respirology TI - A 61-year-old man with recurrent pneumonia UR - https://www.embase.com/search/results?subaction=viewrecord&id=L70576610&from=export http://dx.doi.org/10.1111/j.1400-1843.2011.02071.x VL - 16 ID - 531 ER - TY - JOUR AB - Introduction:A case of aortoesophageal fistula from an undiagnosed coarctation of the aorta and mycotic aneurysm presenting with a massive upper gastronintestinal hemorrhage. Case Description:A 15 year old Caucasian male without significant past medical history presented with epigastric pain and hematemesis. He reported 3 weeks of intermittent fevers, malaise, and weight loss. One week prior to admission, he developed epigastric pain that radiated to his back and non-bloody emesis. On the day of admission, he vomited bright red blood with clots. His physical exam revealed an ill-appearing, pale male. His temperature was 38.4°C, and heart rate was 130 beats per minute. His blood pressure was 133/62. He had a systolic ejection murmur at the left sternal border. His upper and lower extremity pulses were normal, but he had delayed capillary refill and cool extremities. He had tenderness to palpation over the epigastrum without peritoneal signs. Labs revealed a hemoglobin of 6.1 g/dL, platelet count of 244,000, INR of 1.41, and prothrombin time of 23 seconds. Blood culture was positive for Streptococcus pneumoniae. He underwent an upper endoscopy, visceral arteriogram, and abdominal CT angiography without identification of bleeding source. Due to continued bleeding, a second visceral arteriogram was done and was extended to include thoracic aortography. This study showed coarcation of the aorta, presumed mycotic aneurysm distal to the coarctation, and an aortoesophageal fistula. He required excision of the infected tissue, repair of the aorta with an interposition graft, repair of esophageal perforation, diversion esophagostomy, gastrostomy tube placement, and prolonged antibiotic therapy. (Figure presented) Discussion: Aortoesophageal fistula represents a rare but often fatal cause of upper gastrointestinal bleeding. The leading causes are esophageal foreign body and congenital cardiac or vascular anomalies with prolonged nasogastric and/or endotracheal intubations. A protracted unrepaired aortic coarctation led to this patient's mycotic aneurysm and subsequent aortoesophageal fistula. Although it is unclear whether echocardiography would have clearly identified the coarctation or mycotic aneurysm, this quick, noninvasive test may have proven useful on two separate occasions. First, prior to his acute presentation, he likely had long-standing hypertension, which could have prompted work-up including evaluation for coarctation. Earlier diagnosis and treatment would have prevented this near-lethal complication. Second, echocardiography may have been a useful in this unstable patient after the initial radiographic studies revealed no source of bleeding. A high index of suspicion and early multidisciplinary intervention are essential for survival of patients with aortoesophageal fistula. AD - C.R. Okada, Children's Hospital Colorado, University of Colorado at Denver, Aurora, CO, United States AU - Okada, C. R. AU - Mourani, P. M. AU - Dobyns, E. L. AU - Grayck, E. N. AU - Ibrahim, J. E. DB - Embase KW - hemoglobin aorta American society male aortoesophageal fistula human mycotic aneurysm bleeding patient arteriography epigastric pain echocardiography blood vomiting computed tomographic angiography blood culture body weight loss platelet count prothrombin time Caucasian malaise palpation fever capillary congenital blood vessel malformation aortic coarctation diagnosis survival pulse rate Streptococcus pneumoniae endoscopy esophagus foreign body upper gastrointestinal bleeding leg aortography hematemesis systolic heart murmur stomach tube blood pressure esophagostomy esophagus perforation heart rate antibiotic therapy endotracheal intubation tissue repair excision hypertension temperature medical history international normalized ratio LA - English M3 - Conference Abstract N1 - L71981618 2015-09-08 PY - 2013 SN - 1073-449X ST - A 15 year old male with an unusual presentation of coartation of the aorta T2 - American Journal of Respiratory and Critical Care Medicine TI - A 15 year old male with an unusual presentation of coartation of the aorta UR - https://www.embase.com/search/results?subaction=viewrecord&id=L71981618&from=export http://www.atsjournals.org/doi/pdf/10.1164/ajrccm-conference.2013.187.1_MeetingAbstracts.A2249 VL - 187 ID - 478 ER - TY - JOUR AB - Introduction: Wheezing in infants is common, often unresponsive to bronchodilators, and usually improves over time. Therefore it can be challenging to determine when the benefits of an extensive diagnostic workup outweigh the risks. Unusual etiologies include anatomic anomalies, foreign body aspiration, endobronchial masses or external bronchial compression. Mediastinal masses in children are uncommon, and could have oncologic, infectious or embryologic origins. We report an 11 month-old with persistent wheeze unresponsive to therapy. Case Report: An 11 month previously health male infant was referred for evaluation of persistent wheeze for almost 2 months, unresponsive to inhaled bronchodilators and corticosteroids. There was no history suggestive of foreign body aspiration. There was a history of travel to Mexico, but no history of contact with tuberculosis. On physical examination, breath sounds seemed diminished on the left compared to the right, and there was an intermittent wheeze heard more loudly on the left. Previous chest x-rays were reported to be normal, but review suggested the left lung was more lucent than the right. CT and MRI suggested a middle mediastinal mass, 3 x 4 cm, with extension into the left main-stem bronchus. Blood counts, routine chemistry, ESR, CRP, quantitative immunoglobulins, fungal serology, and an interferon-gamma release assay for tuberculosis were all within normal limits. Mantoux was non-reactive. Blood cultures showed no growth. Flexible bronchoscopy confirmed an endobronchial mass, 1 cm in diameter, with > 90% occlusion of the left bronchus. With the assistance of Interventional Pulmonology, the mass was removed piecemeal with a biopsy forceps using a 4.0 mm OD flexible bronchoscope inserted through a laryngeal mask airway (LMA). Gram/Giemsa and AFB stains were non-conclusive. Histopathology reported necrotizing granuloma, etiology unknown. Subsequently, the mediastinal mass was removed by video-assisted thoracoscopic surgery. Smears/stains were negative, and histopathology confirmed necrotizing granulomas from which Mycobacterium avium complex was cultured. Subsequent history revealed the child often played in the soil/dirt on their family farm. Discussion: NTM presenting as a mediastinal mass with endobronchial occlusion has not been previously reported in infants less than 1 year of age. This case highlights the importance of close monitoring and evaluation of a young, otherwise healthy infant with persistent wheeze non-responsive to bronchodilators. Radiologic reports can be misleading. A detailed environmental history, even in very young children, can contribute to diagnosis. Interventional flexible bronchoscopic techniques can permit removal of endobronchial masses in young children without intubation and potential morbidities of rigid bronchoscopy. AD - D.A. Krich, Pediatric Pulmonology, New York Medical College, Valhalla, NY, United States AU - Krich, D. A. AU - Krishnan, S. AU - Harris, K. N. AU - Arlievsky, N. AU - Dozor, A. J. DB - Embase IS - MeetingAbstracts KW - bronchodilating agent corticosteroid endogenous compound immunoglobulin biopsy forceps blood cell count blood culture boy chemistry child conference abstract diagnosis fiberoptic bronchoscopy flexible bronchoscope foreign body aspiration granuloma histopathology human human cell human tissue in vitro study infant interferon gamma release assay intubation laryngeal mask left lung male mediastinum mass Mexico monitoring morbidity Mycobacterium avium complex nonhuman nuclear magnetic resonance imaging occlusion physical examination pulmonology serology soil stain thorax radiography travel tuberculosis video assisted thoracoscopic surgery wheezing LA - English M3 - Conference Abstract N1 - L622966171 2018-07-16 PY - 2018 SN - 1535-4970 ST - 11 month old infant with a mediastinal mass with endobronchial extension presenting as persistent wheeze T2 - American Journal of Respiratory and Critical Care Medicine TI - 11 month old infant with a mediastinal mass with endobronchial extension presenting as persistent wheeze UR - https://www.embase.com/search/results?subaction=viewrecord&id=L622966171&from=export VL - 197 ID - 356 ER - TY - JOUR AB - Purpose: To assess the epidemiological characteristics, types of injury, visual outcomes and complications in patients presenting with open globe injuries (OGIs). Methods: Retrospective chart review. Results: This study included 115 eyes of 114 patients (77% males, 23% females) with a mean age of 41.15 ± 23.0 years (range 1-98). Mean follow up was 10.00 ± 14.4 months. Injuries were penetrating (60.5%), rupture (36.7%) and perforating (2.8%) in nature, and of these, 14.6% were associated with intraocular foreign bodies. Ocular injuries were graded as zone 1 (53%), zone 2 (25%) and zone 3 (21%). Visual acuity (VA) at presentation ranged from: no light perception (NLP) (8%), light perception (LP) (27%), hand movements (HM)(12%), counting fingers (CF)(11%), 6/60-6/36 (4%) and better than 6/ 24 (19%). All but 7 cases underwent primary repair (94 eyes) or evisceration (14 eyes) within 24 hours of presentation. Final VA ranged from: NLP (9%), LP (9%), HM (2%), CF (9%), 6/60-6/36 (13%) and better than 6/24 (58%). Of patients with Final VA better than 6/24, zone 1 injuries made up (70%), zone 2 (20%) and zone 3 (10%). Pre-hospital intubation was required in 7.3% of patients and significant extraocular injuries were noted in 30% of patients. Nineteen eyes had post-operative complications, including wound leak (9), wound infection (4), endophthalmitis (3), raised IOP (2) and graft rejection (1). Conclusions: The Hunter-New England network encounters a broad range of OGIs, often associated with traumatic co-morbidities. Visual outcomes and complication rates are equivalent to previous studies. AD - H. Birrell, Department of Ophthalmology, John Hunter Hospital, Newcastle, NSW, Australia AU - Birrell, H. AU - Viswanathan, D. AU - Haider, A. AU - Singh, R. DB - Embase DO - 10.1111/ceo.12857 KW - adolescent adult aged child comorbidity controlled study endophthalmitis evisceration eye injury female finger follow up graft rejection hand movement human infant intraocular foreign body intraocular pressure intubation major clinical study male medical record review New South Wales perception rupture tertiary care center United States visual acuity wound infection LA - English M3 - Conference Abstract N1 - L613435129 2016-12-01 PY - 2016 SN - 1442-9071 SP - 113 ST - A 10-year review of traumatic open globe injuries at a tertiary referral hospital in New South Wales, Australia: Assessing the epidemiology, aetiology, complications and final visual outcomes of traumatic open globe injuries T2 - Clinical and Experimental Ophthalmology TI - A 10-year review of traumatic open globe injuries at a tertiary referral hospital in New South Wales, Australia: Assessing the epidemiology, aetiology, complications and final visual outcomes of traumatic open globe injuries UR - https://www.embase.com/search/results?subaction=viewrecord&id=L613435129&from=export http://dx.doi.org/10.1111/ceo.12857 VL - 44 ID - 390 ER - TY - JOUR AB - BACKGROUND CONTEXT: Poly-ether-ether-ketone (PEEK) has been the most commonly used biomaterial for spinal fusion for many years, primarily because it meets the necessary mechanical requirements to support the pressures to which the spinal column is subjected. However, the biologic response to PEEK has serious limitations including a persistent foreign body response, very modest osseointegration which can result in micromotion, pain, or worse, delamination requiring surgical reintervention. Recent advances in our understanding of immunobiology show that PEEK elicits a proinflammatory phenotype among cells of the innate immune system, including macrophages. Numerous studies have shown that macrophage phenotype can be predictive of clinical outcome. The host immune response to biomaterials used in spine surgery has been largely ignored in deference to mechanical and biomaterial properties such as peak load bearing, porosity and surface characteristics. Pro-inflammatory (M1-like) macrophages have been shown to release several mediators of cell behavior such as IL-6, IL-1b, and TNF-a, that are osteoclastogenic, while pro-healing (M2-like) macrophages are associated with the release of osteoblastogenic signaling molecules. The emergence of “immunomodulatory biomaterials” is directed toward the biologic consequences associated with permanent implants such as spinal fusion materials. Surface modification of such materials represents one approach for developing more host friendly, biocompatible materials while retaining the required mechanical properties. PURPOSE: The objective of the present study was to characterize and compare the macrophage phenotype elicited by the ZFuze polymer, PEEK, titanium-based alloys, or iterations of modified ZFuze polymer. The ability of these materials to promote differentiation of osteoblast-like cells in vitro was also determined. STUDY DESIGN/SETTING: Macrophage activation study: Primary bone marrow-derived derived macrophages were isolated from C57bl6/j mice and plated on one of the following test articles: ZFuzeTM, PEEK, rough surface titanium alloy, or iterations of modified ZFuze polymer. Gene and protein expression were determined through qPCR and immunolabeling, respectively. Osteoblast differentiation assay: Saos-2 cells were purchased from ATCC. 1*104 cells/cm2 were plated into 6 well tissue culture plates containing test articles composed of: ZFuzeTM, PEEK, rough surface titanium alloy, or iterations of modified ZFuze polymer. Gene and protein expression were determined through qPCR and ELISA, respectively. OUTCOME MEASURES: qPCR, immunolabeling, and ELISA. METHODS: Culture of bone marrow derived macrophages: Bone marrow was isolated from the femurs and tibias of C57bl/6 mice and subsequently cultured in complete growth media, including Dulbecco's modified Eagles medium, 10% fetal bovine serum (FBS), 10% L929 supernatant, 0.1% beta-mercaptoethanol, 100 U/mL penicillin, 100 μg/mL streptomycin, 10 mM nonessential amino acids, and 10 mM HEPES buffer, for 7 days with complete media changes every 48 hours until mature bone marrow-derived macrophages were obtained. Macrophage activation: Mature macrophages were exposed to the following treatments for 24 hours: complete media (M0 control), 20 ng/ml IFN-γ and 100 ng/mL lipopolysaccharide LPS (M1 control), 20 ng/mL interleukin IL-4 (M2 control), PEEK, ZFuze, rough-surface titanium alloy, or ZFuze surface modification iterations. For the cytokine challenge study, cells were exposed for 6 hours to 20 ng/ml IFN-γ and 100 ng/mL LPS, washed and then placed in 10% FBS 1% P/S DMEM for 24 hours. Macrophage immunolabeling: Fixed cells were washed with 1X PBS followed by incubation in a blocking solution composed of PBS, 0.1% Triton-X, 0.1% Tween-20, 4% goat serum, and 2% bovine serum albumin for 1 hour at room temperature. Cells were then incubated in a solution of one of the following primary antibodies: anti-F4/80 at 1:100 dilution as a pan-macrophage marker, anti-inducible nitric oxide synthase (iNOS) at 1:100 dilution as an M1-like marke , and anti-Fizz1 and anti-Arginase1 at 1:200 dilution, each as M2-like markers. Nuclei were counterstained with DAPI. Saos-2 culture: Saos-2 cells were purchased from ATCC. Cells were grown in culture medium comprised of EMEM supplemented with 10% heat-inactivated fetal bovine serum (FBS) and 1% penicillin/streptomycin. Medium was changed every 48 hours. 1*104 cells/cm2 were plated into 6 well tissue culture plates containing test articles composed of either ZFuze, PEEK, rough surface titanium, or iterations of modified ZFuze polymer. Upon reaching confluence, fresh medium was added for 24 hours, and subsequently collected for protein expression determination by ELISA, and then the cells were trypsinized for cell counting and subsequently lysed with TRIzol reagent for RNA isolation. Isolated RNA was then converted to cDNA and gene expression was assessed by qPCR: GAPDH, BMP2, and BMP4. Collected medium was assessed for relative levels of: osteocalcin, BMP2, BMP4, and BMP7. Relative gene and protein expression levels were normalized to cell number and quantified to make relative assessments of differentiation status as a function of test article. RESULTS: Macrophage gene and protein expression: Across three biological replicates, results of qPCR analyses show that ZFuze promoted an M2-like phenotype with expression of Fizz1, and decreased expression of IL-1b and TNF-a compared to PEEK and titanium, which elicited a more “M1-like” macrophage phenotype. Further, zeolite-loaded ZFuze promoted significantly greater expression of Fizz1 by both gene and protein expression than unloaded ZFuze or other test article comparators. Saos-2 osteoblast-like cell gene and protein expression: Aggregated biological replicates show that BMP4 gene expression was upregulated in a statistically significant manner in Saos-2 cells exposed to ZFuze, but not PEEK or rough surface titanium alloy. The expression of BMP2 was also significantly elevated at the translational level in ZFuze, but not PEEK or rough surface titanium, exposed Saos-2 cells. CONCLUSIONS: ZFuze and its iterations elicit a favorable and more biocompatible in vitro immune profile than PEEK or titanium. ZFuze also supports increased expression of osteoblastic differentiation markers’ differentiation of progenitor cells in vitro. FDA DEVICE/DRUG STATUS: ZFuze (Approved for this indication). AD - J. Bartolacci, McGowan Institute for Regenerative Medicine, Pittsburgh, PA, United States AU - Bartolacci, J. AU - Shridhar, A. AU - Badylak, S. F. DB - Embase DO - 10.1016/j.spinee.2020.05.111 IS - 9 KW - 4 (2 hydroxyethyl) 1 piperazineethanesulfonic acid alloy amino acid arginase 1 biomaterial bone morphogenetic protein 2 bone morphogenetic protein 4 bovine serum albumin cell protein complementary DNA endogenous compound gamma interferon glyceraldehyde 3 phosphate dehydrogenase inducible nitric oxide synthase interleukin 1beta interleukin 4 interleukin 6 lipopolysaccharide mercaptoethanol octoxinol osteocalcin osteogenic protein 1 penicillin derivative polyetheretherketone polysorbate 20 streptomycin titanium tumor necrosis factor zeolite animal cell animal experiment animal tissue antibody labeling bone marrow derived macrophage C57BL 6 mouse cell count cell counting cell function clinical outcome conference abstract controlled study culture medium dilution eagle enzyme linked immunosorbent assay femur fetal calf serum goat heat human immune response implant macrophage activation male mouse nonhuman osteoblast outcome assessment phenotype porosity protein expression level quantitative analysis RNA isolation room temperature SaOS-2 cell line signal transduction spine fusion stem cell supernatant tibia tissue culture LA - English M3 - Conference Abstract N1 - L2007747225 2020-09-15 PY - 2020 SN - 1878-1632 1529-9430 SP - S4-S5 ST - 8. Modifiable polymer promotes a pro-osteogenic, M2-like macrophage phenotype and osteoblastic differentiation of progenitor cells T2 - Spine Journal TI - 8. Modifiable polymer promotes a pro-osteogenic, M2-like macrophage phenotype and osteoblastic differentiation of progenitor cells UR - https://www.embase.com/search/results?subaction=viewrecord&id=L2007747225&from=export http://dx.doi.org/10.1016/j.spinee.2020.05.111 VL - 20 ID - 270 ER - TY - JOUR AD - Poison Control Center, Division of Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, United States Division of Pediatric General, Children's Hospital of Philadelphia, Thoracic and Fetal Surgery, Philadelphia, PA, United States Division of Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, United States AU - Osterhoudt, K. C. AU - Peranteau, W. H. AU - Shaw, K. N. AU - Flake, A. W. DB - Scopus DO - 10.1097/PEC.0b013e3182795f80 IS - 12 KW - foreign bodies intestinal perforation magnets M3 - Article N1 - Export Date: 10 November 2020 PY - 2012 SP - 1406-1408 ST - A 2-year-old girl with abdominal pain after an action sure to attract attention T2 - Pediatric Emergency Care TI - A 2-year-old girl with abdominal pain after an action sure to attract attention UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84871630584&doi=10.1097%2fPEC.0b013e3182795f80&partnerID=40&md5=3004f8f8f9b374b9ea1ae3c36a70c54c VL - 28 ID - 1348 ER - TY - JOUR AB - Background: Aseptic, sheet-like foreign bodies observed inside Tenckhoff(TK) catheter lumens (referred to as “black particles”) are, on gross morphology, hardly distinguishable from fungal colonization because these contaminants adhere tightly to the catheter. Detection of fungal cell wall components using (1→3)-β-d-glucan (BG) and galactomannan index (GMI) might be an alternative method for differentiating the particles. Methods: Foreign particles retrieved from TK catheters in 19 peritoneal dialysis patients were examined microscopically and cultured for fungi and bacteria. Simultaneously, a Fungitell test (Associates of Cape Cod, Falmouth, MA, USA) and a Platelia Aspergillus ELISA assay (Bio-Rad Laboratories, Marnes-La-Coquette, France) were used to test the spent dialysate for BG and GMI respectively. Results: Of the 19 patients, 9 had aseptic black particles and 10 had fungal particles in their tubing. The fungal particles looked grainy, were tightly bound to the catheter, and appeared more “colorful” than the black particles, which looked sheet-like and could easily be removed by milking the tubing. Compared with effluent from patients having aseptic particles, effluent from patients with fungal particles had significantly higher levels of BG (501 ± 70 pg/mL vs. 46 ± 10 pg/mL) and GMI (10.98 ± 2.17 vs. 0.25 ± 0.05). Most of the fungi that formed colonies inside the catheter lumen were molds not usually found in clinical practice, but likely from water or soil, suggesting environmental contamination. Interestingly, in all 10 patients with fungal colonization, visualization of black particles preceded a peritonitis episode and TK catheter removal by approximately 1-3 weeks; in patients with aseptic particles, a 17-week onset to peritonitis was observed. Conclusions: In all patients with particle-coated peritoneal dialysis tubing, spent dialysate should be screened for BG and GMI. Manipulation of the TK catheter by squeezing, hard flushing, or even brushing to dislodge black particles should be avoided. Replacement of the TK catheter should be suspended until a cause for the particles is determined. © 2016 International Society for Peritoneal Dialysis. AD - Departments of Microbiology and of Preventive and Social Medicine, Chulalongkorn University, Bangkok, Thailand Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States Sappasit Prasong Hospital, Ubon Ratchathani, Thailand Kidney and Metabolic Research Unit, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand Peritoneal Dialysis Excellent Center, King Chulalongkorn Memorial Hospital, Bangkok, Thailand Division of Nephrology, Department of Medicine, Faculty of Medicine Chulalongkorn University, Bangkok, Thailand AU - Leelahavanichkul, A. AU - Pongpirul, K. AU - Thongbor, N. AU - Worasilchai, N. AU - Petphuak, K. AU - Thongsawang, B. AU - Towannang, P. AU - Lorvinitnun, P. AU - Sukhontasing, K. AU - Katavetin, P. AU - Praditpornsilpa, K. AU - Eiam-Ong, S. AU - Chindamporn, A. AU - Kanjanabuch, T. DB - Scopus DO - 10.3747/pdi.2014.00235 IS - 4 KW - (1→3)-β-d-glucan Black particles CAPD Fungal colonization Fungal peritonitis Galactomannan M3 - Article N1 - Cited By :5 Export Date: 10 November 2020 PY - 2016 SP - 402-409 ST - (1→3)-β-D-glucan and galactomannan for differentiating chemical “Black particles” and fungal particles inside peritoneal dialysis tubing T2 - Peritoneal Dialysis International TI - (1→3)-β-D-glucan and galactomannan for differentiating chemical “Black particles” and fungal particles inside peritoneal dialysis tubing UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84977473070&doi=10.3747%2fpdi.2014.00235&partnerID=40&md5=3c3be13a31aace90f183f8b84aa25081 VL - 36 ID - 1178 ER - TY - JOUR AB - BACKGROUND: A retained foreign object (RFO) is a devastating surgical complication that typically results in additional surgeries, increased length of stay, and risk of infections and is potentially fatal. Memorial Sloan Kettering Cancer Center (MSKCC) convened a multidisciplinary task force to undertake an improvement initiative to reduce the frequency of RFO incidents. METHODS: A needs assessment was undertaken using focus group interviews, review of past RFOs, and operating room (OR) observations, and a comprehensive intervention plan was initiated. Items at risk of retention were reclassified and new tracking sheets were developed. A probabilistic risk model was developed based on aviation industry methodology, an RFO risk projection, and the retention risk classification of surgical items. Training initiatives were launched to shift organizational culture and staff behaviors toward greater awareness of RFO risk and proactive prevention. RESULTS: Since the implementation of our task force's recommendations on March 24, 2014, there have been no RFO incidents at our institution to this day. The last RFO occurred in August 2013-more than 1,300 days ago (as of March 28, 2017). The RFO incident frequency was reduced from 1.69 per year to a risk model estimate of 1 in 22 years. Ongoing training maintains the staff's behavioral changes as well as the improved OR and organizational culture. CONCLUSION: Implementation of a multidisciplinary approach to preventing RFOs was successful at MSKCC. The use of an RFO risk model enabled the creation of a robust system for RFO prevention. Support from leadership, participation by all stakeholders, education, training, and cooperation from frontline staff are all important contributors to RFO prevention success. AN - 29759259 AU - Duggan, E. G. AU - Fernandez, J. AU - Saulan, M. M. AU - Mayers, D. L. AU - Nikolaj, M. AU - Strah, T. M. AU - Swift, L. M. AU - Temple, L. DA - May DO - 10.1016/j.jcjq.2017.11.006 DP - NLM ET - 2018/05/16 IS - 5 KW - Foreign Bodies/*prevention & control Hospital Administration/standards Humans Leadership Operating Rooms/*organization & administration/standards Organizational Culture Patient Safety/standards Program Development Program Evaluation Quality Improvement/*organization & administration/standards Risk Factors *Surgical Instruments LA - eng N1 - Duggan, Erika G Fernandez, Jimmy Saulan, Mary May Mayers, Dave L Nikolaj, Mira Strah, Tamara M Swift, Lystra M Temple, Larissa P30 CA008748/CA/NCI NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Netherlands Jt Comm J Qual Patient Saf. 2018 May;44(5):260-269. doi: 10.1016/j.jcjq.2017.11.006. PY - 2018 SN - 1553-7250 (Print) 1553-7250 SP - 260-269 ST - 1,300 Days and Counting: A Risk Model Approach to Preventing Retained Foreign Objects (RFOs) T2 - Jt Comm J Qual Patient Saf TI - 1,300 Days and Counting: A Risk Model Approach to Preventing Retained Foreign Objects (RFOs) VL - 44 ID - 214 ER -