TY  - JOUR
ID  - 106243570
T1  - A capital approach: Tobacco treatment and cessation within Nova Scotia's Capital Health District.
AU  - Jolemore S
AU  - Steeves D
Y1  - 2006/09//
N1  - Accession Number: 106243570. Language: English. Entry Date: 20070302. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Canada; Editorial Board Reviewed; Expert Peer Reviewed; Health Services Administration; Peer Reviewed. Special Interest: Psychiatry/Psychology; Public Health. NLM UID: 101208192. 
KW  - Smoking Cessation
KW  - Smoking -- Prevention and Control -- Nova Scotia
KW  - Tobacco
KW  - Nova Scotia
SP  - 66
EP  - 70 5p
JO  - Healthcare Quarterly
JF  - Healthcare Quarterly
JA  - HEALTHC Q
VL  - 9
IS  - 3
CY  - Toronto, Ontario
PB  - Longwoods Publishing
AB  - Inspired by Nova Scotia's comprehensive Tobacco Control Strategy and in an effort to support Capital Health's 100% smoke-free policy, the Addiction Prevention and Treatment Services (APTS) branch of Capital District Health Authority researched, designed and implemented an innovative tobacco intervention program. The success of the Capital approach, combining peer support, adult education concepts, addictions treatment knowledge, and free pharmacological aids, has sparked interest and dialogue among Canadian and American addictions professionals. The following article describes the rationale, guiding principles, key components and future directions of APTS's 'To Be Tobacco Free' program.
SN  - 1710-2774
AD  - Capital Health Addiction Prevention & Treatment Services, Dartmouth, Nova Scotia.
U2  - PMID: 16826769.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106243570&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109680863
T1  - A culturally competent education program to increase understanding about medicines among ethnic minorities.
AU  - Cantarero-Arévalo, Lourdes
AU  - Kassem, Dumoue
AU  - Traulsen, Janine Marie
Y1  - 2014/10//
N1  - Accession Number: 109680863. Language: English. Entry Date: 20150605. Revision Date: 20151001. Publication Type: journal article. Journal Subset: Biomedical; Continental Europe; Europe. NLM UID: 101554912. 
SP  - 922
EP  - 932 11p
JO  - International Journal of Clinical Pharmacy
JF  - International Journal of Clinical Pharmacy
JA  - INT J CLIN PHARM
VL  - 36
IS  - 5
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
AB  - Background: It has been previously suggested that the risk of medicine-related problems-i.e., negative clinical outcomes, adverse drug reactions or adverse drug events resulting from the use (or lack of use) of medicines, and human error including that caused by healthcare personnel-is higher among specific ethnic minority groups compared to the majority population.Objective: The focus of this study was on reducing medicine-related problems among Arabic-speaking ethnic minorities living in Denmark. The aim was twofold: (1) to explore the perceptions, barriers and needs of Arabic-speaking ethnic minorities regarding medicine use, and (2) to use an education program to enhance the knowledge and competencies of the ethnic minorities about the appropriate use of medicines.Settings: Healthcare in Denmark is a tax-financed public service that provides free access to hospitals and general practitioners. In contrast to the USA or the UK, serving ethnically diverse populations is still a relatively new phenomenon for the Danish healthcare system. Ethnic minorities with a non-Western background comprised a total of 6.9 % of the Danish population.Methods: Data were collected through qualitative research. Four focus group interviews were conducted before and four after the education program. Thirty Arabic-speaking participants were recruited from language and job centers in Copenhagen. Participants received teaching sessions in Arabic on appropriate medicine use. The education program was evaluated by two methods: a written quiz for knowledge evaluation and focus group interviews for process evaluation. It took place during the first semenester of 2012. Results The majority of the participants were dissatisfied with the knowledge about medicines inherited from their parents. They also expressed their frustrations due to communication problems with Danish doctors. According to the impressions and quiz results of participants, the program was relevant, rich in information and effective. The program helped bridge the gap between participants and doctors. The commonality of the culture, language and gender shared by the researcher pharmacist and participants enhanced the success of the program.Conclusion: The education program may potentially reduce medicine-related problems by providing participants with knowledge and competencies about appropriate medicine use. We recommend implementing education programs for ethnic minorities using the cultural competence approach to the appropriate use of medicines. Ideally, programs should be implemented in places that are frequented by ethnic minorities, and taught by health professionals with the same ethnic background as participants.
SN  - 2210-7703
U2  - PMID: 25193266.
DO  - 10.1007/s11096-014-0009-8
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106793769
T1  - A depression management programme reduced depression in frequent users of healthcare but did not reduce healthcare visits.
AU  - Peveler R
Y1  - 2001/08//
N1  - Accession Number: 106793769. Language: English. Entry Date: 20030103. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary; tables/charts. Original Study: Katzelnick DJ, Simon GE, Pearson SD, et al. Randomized trial of a depression management program in high utilizers of medical care. Arch Fam Med 2000 Apr; 9: 345-51. Journal Subset: Biomedical; Europe; UK & Ireland. NLM UID: 100883413. 
KW  - Depression -- Rehabilitation
KW  - Cost Benefit Analysis
KW  - Treatment Outcomes
KW  - Health Maintenance Organizations
SP  - 78
EP  - 79 2p
JO  - Evidence Based Mental Health
JF  - Evidence Based Mental Health
JA  - EVID BASED MENT HEALTH
PB  - BMJ Publishing Group
AB  - QUESTION: Does a programme to identify and treat depression in frequent users of medical care improve clinical outcomes and reduce total healthcare use?DesignCluster randomised {allocation concealment*}** blinded (telephone assessment)*, controlled trial with 1 year of follow up.SettingPrimary care clinics of 3 health management organisations (HMOs) in the US (Wisconsin, Washington, and Massachusetts).Patients407 patients who were 25-63 years of age (mean age 45 y, 77% women) with continuous health plan enrolment for >/=2 years, were frequent healthcare users (ambulatory visits per year above the 85th percentile for previous 2 years), and screened positive for current major depression or major depression in partial remission with a score >/= 15 on the Hamilton Depression Rating Scale (HDRS). 47% had >/= 1 chronic medical disorder. Exclusion criteria included recent treatment for substance abuse, previous treatment for schizophrenia or bipolar disorder, life threatening medical illness, or active mental health specialty treatment for depression. 93% of patients completed the blinded telephone assessment at 12 months.Intervention82 physician practices were allocated to the depression management programme (DMP) (n = 218), and 81 were allocated to usual care (n=189). DMP consisted of physician education (2 hour training session and provision of psychiatrists as consultants at each HMO), patient education (a booklet entitled Depression isn't just a medical problem and videotaped educational materials), antidepressant treatment (pharmacotherapy algorithm adjusted for individual clinical need), and treatment coordination.Main outcome measuresChange in HDRS scores and number of healthcare visits.Main resultsAnalysis was by intention to treat Patients in the DMP group had greater improvements in depression score at 6 weeks (p=0.04), 3 months (p=0.02), 6 months (p < 0.001), and 12 months (p < 0.001) than patients in the usual care group (table). Patients in the DMP group had more healthcare visits (mean increase 1.6 visits) during 12 months of follow up relative to the previous year whereas patients in the usual care group had a decrease in healthcare visits (mean decrease 2.0 visits) (p = 0.02 for the difference between groups).ConclusionIn depressed patients who are frequent users of general medical care, a depression management programme led to greater clinical improvement but did not decrease healthcare visits.*See glossary.**Information provided by author.
SN  - 1362-0347
AD  - University of Southampton and Royal South Hants Hospital, Southampton,UK
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104338209
T1  - A Guided Interview Process to Improve Student Pharmacists' Identification of Drug Therapy Problems.
AU  - Rovers, John
AU  - Miller, Michael J.
AU  - Koenigsfeld, Carrie
AU  - Haack, Sally
AU  - Hegge, Karly
AU  - McCleeary, Erin
Y1  - 2011/01//
N1  - Accession Number: 104338209. Language: English. Entry Date: 20130301. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; USA. 
SP  - 1
EP  - 6 6p
JO  - American Journal of Pharmaceutical Education
JF  - American Journal of Pharmaceutical Education
JA  - AM J PHARMACEUTICAL EDUC
VL  - 75
IS  - 1
CY  - Alexandria, Virginia
PB  - American Association of Colleges of Pharmacy
SN  - 0002-9459
AD  - Drake University College of Pharmacy and Health Sciences
AD  - University of Oklahoma College of Pharmacy
AD  - South Dakota State University College of Pharmacy
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107202174
T1  - A pilot project: continuing education for pharmacists on substance abuse prevention.
AU  - Graham A
AU  - Pfeifer J
AU  - Trumble J
AU  - Nelson ED
Y1  - 1999/03//
N1  - Accession Number: 107202174. Language: English. Entry Date: 19990801. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Grant Information: Supported in part by Contract 277-93-1029 from the Center for Substance Abuse Prevention. NLM UID: 8808537. 
KW  - Substance Abuse -- Prevention and Control
KW  - Education, Pharmacy
KW  - Pilot Studies
KW  - Convenience Sample
KW  - Interviews
KW  - Education, Continuing
KW  - Health Education
KW  - Male
KW  - Female
KW  - Funding Source
KW  - Human
SP  - 33
EP  - 43 11p
JO  - Substance Abuse
JF  - Substance Abuse
JA  - SUBST ABUSE
VL  - 20
IS  - 1
PB  - Taylor & Francis Ltd
AB  - The American Association of Colleges of Pharmacy advocates that pharmacists can have a significant impact on substance abuse prevention provided they receive adequate training. Continuing education programs are needed to enable practicing pharmacists to augment their limited education. This paper examines the process the Society of Teachers of Family Medicine (STFM) used to develop a pilot continuing education program for pharmacists. With limited literature and a small number of pharmacy teaching about substance abuse, input on topics and training methods was obtained from a convenience sample of practicing pharmacists to enhance the information from the pharmacist faculty regarded as content experts. Results of this pilot study revealed lack of agreement between faculty and practicing pharmacists regarding the prioritizing of content and educational methods. Consequently, input must be obtained from targeted audiences instead of relying solely on the advice of identified academic content experts when designing continuing educational programs. Other professions should consider this process when designing continuing education programs. Pharmacists are poised to play an important role in the prevention of substance abuse problems, but they need continuing education about substance abuse.
SN  - 0889-7077
AD  - Department of Family Medicine, Case Western Reserve University, 10900 Euclid Ave., Cleveland, Ohio 44106-4950
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107787115
T1  - A Primer on Prescription Drug Abuse and the Role of the Pharmacy Director.
AU  - Haruin, Andre
AU  - Weber, Robert J.
Y1  - 2015/05//
N1  - Accession Number: 107787115. Language: English. Entry Date: 20150601. Revision Date: 20150712. Publication Type: Journal Article; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0043175. 
KW  - Substance Abuse -- Mortality
KW  - Physician Executives
KW  - Prescribing Patterns
KW  - Pharmacy and Pharmacology
KW  - United States
KW  - Pharmacists -- Education
KW  - Government Agencies
KW  - Centers for Disease Control and Prevention (U.S.)
KW  - Economics
KW  - Substance Abuse -- Risk Factors
KW  - Pain -- Therapy
KW  - Legal Procedure
KW  - Government Regulations
SP  - 423
EP  - 428 6p
JO  - Hospital Pharmacy
JF  - Hospital Pharmacy
JA  - HOSP PHARM
VL  - 50
IS  - 5
CY  - St. Louis, Missouri
PB  - Thomas Land Publishers Incorporated
SN  - 0018-5787
AD  - Senior Pharmacy Resident, Ohio State University Wexner Medical Center and College of Pharmacy, Columbus, Ohio
AD  - Administrator, Pharmacy Services, Ohio State University Wexner Medical Center and College of Pharmacy, Columbus, Ohio
DO  - 10.1310/hpj5005-423
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107787115&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103993789
T1  - A randomized clinical trial of a financial education intervention with nicotine replacement therapy ( NRT) for low socio-economic status Australian smokers: a study protocol.
AU  - Courtney, Ryan J.
AU  - Bradford, Deborah
AU  - Martire, Kristy A.
AU  - Bonevski, Billie
AU  - Borland, Ron
AU  - Doran, Christopher
AU  - Hall, Wayne
AU  - Farrell, Michael
AU  - Siahpush, Mohammad
AU  - Sanson-Fisher, Rob
AU  - West, Robert
AU  - Mattick, Richard P.
Y1  - 2014/10//
N1  - Accession Number: 103993789. Language: English. Entry Date: 20140829. Revision Date: 20151001. Publication Type: Journal Article; research; tables/charts; randomized controlled trial. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology. Grant Information: This research is funded by a grant from the National Health and Medical Research Council (NHMRC) of Australia a (grant number APP1021862).. NLM UID: 9304118. 
KW  - Smoking -- Prevention and Control -- Australia
KW  - Smoking Cessation
KW  - Socioeconomic Factors
KW  - Social Class
KW  - Nicotine Replacement Therapy
KW  - Financial Management -- Education
KW  - Research Protocols
KW  - Australia
KW  - Human
KW  - Interviews
KW  - Random Assignment
KW  - Experimental Studies
KW  - Funding Source
SP  - 1602
EP  - 1611 10p
JO  - Addiction
JF  - Addiction
JA  - ADDICTION
VL  - 109
IS  - 10
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Background and Aims Reducing smoking prevalence among smokers from low socio-economic status ( SES) is a preventative health priority. Financial stress (e.g. shortage of money or inability to pay bills) may be a major barrier to quitting smoking. This study evaluates the efficacy of a financial education and support programme coupled with pharmacotherapy at improving cessation rates at 8-month follow-up among Australian low SES smokers (people receiving a government pension or allowance). Design A two-group parallel block randomized (ratio 1 : 1) open-label clinical trial ( RCT) with allocation concealment will be conducted. Allocation will be concealed to interviewers at data collection-points. Setting The study will be conducted primarily by telephone with baseline, follow-up interviews and telephone-based support sessions. Nicotine replacement therapy ( NRT) delivery will be mail-based. Participants Daily smokers who are interested in quitting smoking and are currently in receipt of government benefits ( n = 1046) will be recruited through study advertisements placed in newspapers, posters placed in government social assistance agencies and Quitline telephone-based cessation support services. After completion of a baseline computer-assisted telephone interview, participants will be allocated randomly to control or intervention group using a permuted block approach. Intervention and Comparator Participants in both groups will receive 8 weeks of free combination NRT plus Quitline support. Participants in the intervention group will also receive four telephone-delivered financial education and support sessions. Measurements The primary outcome measure will be prolonged abstinence (at 8-month follow-up) assessed using Russell Standard criteria and biochemically verified (urine cotinine). Comments This is the first intervention study to evaluate the potential of co-managing financial stress as a means of enhancing smokers' capacity to quit smoking. Such an intervention may provide a scalable intervention to help low SES smokers to quit.
SN  - 0965-2140
AD  - National Drug and Alcohol Research Centre, Medicine, University of New South Wales (UNSW)
AD  - National Drug and Alcohol Research Centre, Medicine, University of New South Wales (UNSW); School of Psychology, UNSW
AD  - School of Medicine and Public Health, University of Newcastle
AD  - Centre for Behavioural Research in Cancer, Cancer Council Victoria
AD  - UQ Centre for Clinical Research, University of Queensland
AD  - College of Public Health, University of Nebraska Medical Center
AD  - UCL Department of Epidemiology and Public Health, University College London
U2  - PMID: 25040447.
DO  - 10.1111/add.12669
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 114089923
T1  - A Reality Check:The Need for a Deeper Understanding of Opioid Abuse Treatment Options:A Policy Statement From the American College of Clinical Pharmacology.
AU  - Rusch, Lorraine M.
Y1  - 2016/01//
N1  - Accession Number: 114089923. Language: English. Entry Date: In Process. Revision Date: 20160331. Publication Type: Article. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0366372. 
SP  - 7
EP  - 10 4p
JO  - Journal of Clinical Pharmacology
JF  - Journal of Clinical Pharmacology
JA  - J CLIN PHARMACOL
VL  - 56
IS  - 1
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 0091-2700
AD  - American College of Clinical Pharmacology, PO Box 1758, Ashburn, VA 20146, USA.
DO  - 10.1002/jcph.645
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104986827
T1  - A retrospective study of drug-related problems in Australian aged care homes: medication reviews involving pharmacists and general practitioners.
AU  - Nishtala PS
AU  - McLachlan AJ
AU  - Bell JS
AU  - Chen TF
Y1  - 2011/02//
N1  - Accession Number: 104986827. Language: English. Entry Date: 20110203. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; Public Health; UK & Ireland. Special Interest: Gerontologic Care; Public Health. NLM UID: 9609066. 
KW  - Adverse Drug Event -- Epidemiology -- In Old Age
KW  - Residential Facilities -- In Old Age
KW  - Pharmacists
KW  - Physicians, Family
KW  - Adverse Drug Event -- Prevention and Control -- In Old Age
KW  - Human
KW  - Retrospective Design
KW  - New South Wales
KW  - Aged
KW  - Health Facility Administration
KW  - Interprofessional Relations
KW  - Random Sample
KW  - Record Review
KW  - Practice Patterns
KW  - Data Analysis Software
KW  - Descriptive Statistics
KW  - Interrater Reliability
KW  - Kappa Statistic
KW  - Chi Square Test
KW  - Aged, 80 and Over
KW  - Confidence Intervals
SP  - 97
EP  - 103 7p
JO  - Journal of Evaluation in Clinical Practice
JF  - Journal of Evaluation in Clinical Practice
JA  - J EVAL CLIN PRACT
VL  - 17
IS  - 1
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Drug-related problems (DRPs) in Australian aged care homes have been studied previously. However, little is known about the acceptance and implementation of pharmacists' recommendations by general practitioners (GPs) to resolve DRPs. The primary objective of this study was to investigate the number and nature of DRPs identified by accredited clinical pharmacists. The secondary objective was to study the GP acceptance and implementation of pharmacist recommendations to resolve DRPs. This was a retrospective study of 500 randomly selected, de-identified medication reviews performed by 10 accredited clinical pharmacists over 6 months across 62 aged care homes. The DRPs identified by pharmacists were subsequently classified by the drugs involved, types of problem (indication, effectiveness and safety) and medical diagnoses of the patient. GP written feedback on the medication review reports determined implementation of pharmacists' recommendations to resolve the DRPs. A total of 1433 DRPs were identified in 480 of the 500 residents. Potential DRPs were frequently classified as risk of adverse drug reactions, need for additional monitoring and inappropriate choice of a drug. Alimentary, cardiovascular, central nervous system and respiratory drugs were most frequently implicated, accounting for more than 75% of the DRPs. GPs' acceptance and implementation of pharmacists recommendations were 72.5% (95% CI; 70.2, 74.8) and 58.1% (95% CI; 55.5, 60.6), respectively. Over 96% of the residents had potential DRPs identified by pharmacists. GP acceptance of pharmacists' recommendations was independent of the drug category, but not independent of the disease category.
SN  - 1356-1294
AD  - Researcher,
U2  - PMID: 20825538.
DO  - 10.1111/j.1365-2753.2010.01374.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109762625
T1  - A Review of OROS Methylphenidate (Concerta((R))) in the Treatment of Attention-Deficit/Hyperactivity Disorder.
AU  - Katzman, Martin A
AU  - Sternat, Tia
Y1  - 2014/11//
N1  - Accession Number: 109762625. Language: English. Entry Date: 20150717. Revision Date: 20150923. Publication Type: Journal Article; review. Journal Subset: Australia & New Zealand; Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed. NLM UID: 9431220. 
KW  - Attention Deficit Hyperactivity Disorder -- Drug Therapy
KW  - Central Nervous System Stimulants -- Therapeutic Use
KW  - Drug Delivery Systems
KW  - Methylphenidate -- Therapeutic Use
KW  - Administration, Oral
KW  - Central Nervous System Stimulants -- Administration and Dosage
KW  - Clinical Trials
KW  - Delayed-Action Preparations
KW  - Drug Administration Schedule
KW  - Methylphenidate -- Administration and Dosage
KW  - Treatment Outcomes
SP  - 1005
EP  - 1033 29p
JO  - CNS Drugs
JF  - CNS Drugs
JA  - CNS DRUGS
VL  - 28
IS  - 11
PB  - Springer Science & Business Media B.V.
AB  - Attention-deficit/hyperactivity disorder (ADHD) is a common neurobehavioural disorder with onset during childhood. It affects a child's development, both at home and at school, and impacts on social, emotional and cognitive functioning, in both the home and the school environment. Untreated ADHD is very often associated with poor academic achievement, low occupational status, increased risk of substance abuse and delinquency. Current practice guidelines recommend a multimodal approach in the treatment of ADHD, which includes educational, behavioural and mental health interventions, and pharmacological management. Stimulant medications, including methylphenidate (MPH) and amphetamine products, are recommended as first-line pharmacotherapy in the treatment of ADHD. The choice of stimulant is influenced by several factors; the most influential factor is the duration of action. Long-acting medication provides benefits long after school and work. It also increases the likelihood of once-daily dosing, thereby eliminating the need for mid-day dosing, making the treatment more private, avoiding stigma and improving adherence to medication. MPH is the most widely used psychotropic medication in child psychiatry. It was first developed for use in children as an oral, immediate-release formulation and more recently as various extended-release formulations. These latter formulations include the 12 h preparation Concerta((R)) (osmotic-release oral system [OROS] MPH), which utilizes an osmotic pump system, designed to overcome the difficulties of multiple daily dosing. Since it received approval from the US Food and Drug Administration in August 2000, OROS MPH has been quickly and widely accepted as one of the preferred treatments for ADHD because of its once-daily dosing. This paper reviews the data in support of long-acting OROS MPH in children, adolescents and adults, both in ADHD and in association with its comorbidities.
SN  - 1172-7047
AD  - START Clinic for Mood and Anxiety Disorders, 32 Park Road, Toronto, ON, M4W 2N4, Canada, mkatzman@startclinic.ca.
U2  - PMID: 25120227.
DO  - 10.1007/s40263-014-0175-1
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106416312
T1  - A review of pharmacological and educational approaches for tobacco cessation.
AU  - Monson AL
AU  - Romas JA
Y1  - 2005/07//2005 Jul
N1  - Accession Number: 106416312. Language: English. Entry Date: 20060331. Revision Date: 20150818. Publication Type: Journal Article. Journal Subset: Allied Health; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. 
KW  - Psychoeducation
KW  - Smoking Cessation
KW  - Smoking -- Drug Therapy
KW  - Transtheoretical Stages of Change Model
KW  - Behavior, Addictive -- Complications
KW  - Chronic Disease -- Etiology
KW  - Female
KW  - Fetus
KW  - Health Personnel
KW  - Life Style Changes
KW  - Nicotine Replacement Therapy
KW  - Nicotine -- Adverse Effects
KW  - Pregnancy
KW  - Smoking -- Complications
KW  - Smoking -- Complications -- In Utero
KW  - Smoking -- Mortality
KW  - Smoking -- Therapy
KW  - Substance Dependence -- Etiology
SP  - 13p
EP  - 13p 1p
JO  - Internet Journal of Allied Health Sciences & Practice
JF  - Internet Journal of Allied Health Sciences & Practice
JA  - INTERNET J ALLIED HEALTH SCI PRACT
VL  - 3
IS  - 3
CY  - Fort Lauderdale, Florida
PB  - Nova Southeastern University, College of Allied Health
AB  - Assisting patients to quit smoking continues to be critical for all health care providers as the Surgeon General's report in 2004 reported a significant increase in the number of diseases caused by smoking. Awareness of the extreme addictiveness of nicotine may help health care providers increase empathy for patients attempting to quit. Health care providers can identify the patient's stage of change, according to the Transtheoretical Model, and incorporate appropriate pharmacological and educational methods to aid in the quit attempt.
SN  - 1540-580X
AD  - Assistant Professor, Department of Dental Hygiene, Minnesota State University, Mankato, 3 Morris Hall, Mankato, MN 56001; angela.monson@mnsu.edu
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106844146
T1  - A review of the chemistry, biological action, and clinical applications of anabolic-androgenic steroids.
AU  - Shahidi NT
Y1  - 2001/09//2001 Sep
N1  - Accession Number: 106844146. Language: English. Entry Date: 20030627. Revision Date: 20150711. Publication Type: Journal Article; pictorial; review; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7706726. 
KW  - Anabolic Steroids -- Pharmacodynamics
KW  - Anabolic Steroids -- Therapeutic Use
KW  - Anabolic Steroids -- Adverse Effects
KW  - Anabolic Steroids -- Metabolism
KW  - Blood Proteins -- Drug Effects
KW  - Bone and Bones -- Drug Effects
KW  - Bone Marrow -- Drug Effects
KW  - Chemistry, Pharmaceutical
KW  - Clinical Trials
KW  - Edema -- Drug Therapy
KW  - Erythrocytes -- Drug Effects
KW  - Erythropoietin -- Drug Effects
KW  - Hepatitis -- Etiology
KW  - Jaundice -- Etiology
KW  - Kidney Failure, Chronic -- Drug Therapy
KW  - Lipids -- Drug Effects
KW  - Liver Neoplasms -- Etiology
KW  - Muscular Atrophy -- Drug Therapy
KW  - Myocardium -- Drug Effects
SP  - 1355
EP  - 1390 36p
JO  - Clinical Therapeutics
JF  - Clinical Therapeutics
JA  - CLIN THER
VL  - 23
IS  - 9
CY  - Philadelphia, Pennsylvania
PB  - Elsevier Inc.
AB  - BACKGROUND: Since its discovery in 1935, numerous derivatives of testosterone have been synthesized, with the goals of prolonging its biological activity in vivo, producing orally active androgens, and developing products, commonly referred to as anabolic-androgenic steroids (AAS), that are more anabolic and less androgenic than the parent molecule. OBJECTIVE: This article reviews the structure, biotransformation, and mechanism of action of testosterone and some of the most commonly used AAS. Clinical applications of the AAS are discussed, and guidelines and therapeutic maneuvers for minimizing their side effects are outlined. METHODS: Literature for inclusion in this review was identified using the libraries of the University of Wisconsin Medical School and School of Pharmacy, the author's files, and searches of MEDLINE, Science Citation Index, Biological Abstracts, and Chemical Abstracts. RESULTS: The myotrophic action of testosterone and its derivatives and their stimulatory effects on the brain have led to widespread use of AAS by athletes and 'recreational' drug users. Consequently, all AAS were classified as class III controlled substances in 1991. Nonetheless, AAS have shown benefit in a variety of human disorders, including HIV-related muscle wasting and other catabolic conditions such as chronic obstructive pulmonary disease, severe burn injuries, and alcoholic hepatitis. Because of their diverse biological actions, AAS have been used to treat a variety of other conditions, including bone marrow failure syndromes, constitutional growth retardation in children, and hereditary angioedema. AAS therapy is associated with various side effects that are generally dose related; therefore, illicit use of megadoses of AAS for the purpose of bodybuilding and enhancement of athletic performance can lead to serious and irreversible organ damage. The most common side effects of AAS are some degree of masculinization in women and children, behavioral changes (eg, aggression), hepatotoxicity, and alteration of blood lipid levels and coagulation factors. CONCLUSIONS: To minimize or avoid serious toxicities with AAS therapy, close medical supervision and periodic monitoring are important, with dose adjustment as appropriate to achieve the minimum effective dose. Given the biological effects and potential adverse effects of AAS, administration of these agents should be avoided in pregnant women, women with breast cancer or hypercalcemia, men with carcinoma of the prostate or breast, and patients with nephrotic syndromes or significant liver dysfunction.
SN  - 0149-2918
AD  - Professor Emeritus, Dept of Pediatric Hematology and Oncology, University of Wisconsin, 600 Highland Ave, Madison, WI 53792-4672
U2  - PMID: 11589254.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107483415
T1  - A systematic approach to educating elderly patients about their medications.
AU  - Opdycke RAC
AU  - Ascione FJ
AU  - Shimp LA
AU  - Rosen RI
Y1  - 1992/02//1992 Feb
N1  - Accession Number: 107483415. Language: English. Entry Date: 19920401. Revision Date: 20150712. Publication Type: Journal Article; questionnaire/scale; research; tables/charts. Journal Subset: Core Nursing; Europe; Health Promotion/Education; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 8406280. 
KW  - Patient Education -- In Old Age
KW  - Pharmacists
KW  - Self Administration -- Education -- In Old Age
KW  - Patient Satisfaction -- In Old Age
KW  - Patient History Taking
KW  - Patient Compliance -- In Old Age
KW  - Education Research
KW  - Aged
KW  - Male
KW  - Female
KW  - Human
SP  - 43
EP  - 60 18p
JO  - Patient Education & Counseling
JF  - Patient Education & Counseling
JA  - PATIENT EDUC COUNS
VL  - 19
IS  - 1
PB  - Elsevier Science
AB  - The purpose of this study was to evaluate a pharmacist-initiated, total package, patient education program based on the concepts described in the PRECEDE model. This program was directed towards 94 therapeutically complex elderly patients and consisted of a medication history, therapeutic evaluation, patient education needs assessment, patient education needs assessment, patient education session, and a patient feedback/satisfaction telephone inteview. Pharmacists identifed on average 5.6 medication-related problems and provided an average of 6.2 recommendations. Problems commonly identified involved inadequate drug knowledge (25.5%), noncompliance (22.7%), and inappropriate drug use (17.4%). Typical recommendations included altering drug use (35.9%), improving compliance behavior (18.1%), and improving communication with health professionals (18.1%). Patient satisfaction with the education session was overwhelmingly positive. Based on the findings of this study, it is apparent that a patient education program based on the PRECEDE model can be used successfully by pharmacists to prepare education plans that would benefit the therapeutically complex elderly patient.
SN  - 0738-3991
AD  - Coll Pharmacy Univ Michigan, Ann Arbor, MI 48109-1065
U2  - PMID: 1298948.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105444143
T1  - Abstracts Thirty-eighth annual meeting American College of Clinical Pharmacology September 13-15, 2009 San Antonio, Texas.
Y1  - 2009/09//
N1  - Accession Number: 105444143. Language: English. Entry Date: 20091009. Revision Date: 20150711. Publication Type: Journal Article; abstract. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Public Health. NLM UID: 0366372. 
KW  - Antioxidants
KW  - Drug Interactions
KW  - Drugs -- Pharmacodynamics
KW  - Drugs -- Pharmacokinetics
KW  - Smoking -- Complications
KW  - Adverse Drug Event
SP  - 1091
EP  - 1130 40p
JO  - Journal of Clinical Pharmacology
JF  - Journal of Clinical Pharmacology
JA  - J CLIN PHARMACOL
VL  - 49
IS  - 9
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 0091-2700
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109749400
T1  - Academic Detailing Interventions Improve Tobacco Use Treatment among Physicians Working in Underserved Communities.
AU  - Leone, Frank T
AU  - Evers-Casey, Sarah
AU  - Graden, Sarah
AU  - Schnoll, Robert
AU  - Mallya, Giridhar
Y1  - 2015/06//
N1  - Accession Number: 109749400. Language: English. Entry Date: 20150923. Revision Date: 20160326. Publication Type: journal article. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Critical Care. Grant Information: P30 CA016520/CA/NCI NIH HHS/United States. NLM UID: 101600811. 
SP  - 854
EP  - 858 5p
JO  - Annals of the American Thoracic Society
JF  - Annals of the American Thoracic Society
JA  - ANN AM THORAC SOC
VL  - 12
IS  - 6
CY  - New York, New York
PB  - American Thoracic Society
AB  - Rationale: Tobacco use disproportionately affects the poor, who are, in turn, least likely to receive cessation treatment from providers. Providers caring for low-income populations perform simple components of tobacco use treatment (e.g., assessing tobacco use) with reasonable frequency. However, performance of complex treatment behaviors, such as pharmacologic prescription and follow-up arrangement, remains suboptimal.Objectives: Evaluate the influence of academic detailing (AD), a university-based, noncommercial, educational outreach intervention, on primary care physicians' complex treatment practice behaviors within an urban care setting.Methods: Trained academic detailers made in-person visits to targeted primary care practices, delivering verbal and written instruction emphasizing three key messages related to tobacco treatment. Physicians' self-reported frequency of simple and complex treatment behaviors were assessed using a seven-item questionnaire, before and 2 months after AD.Results: Between May 2011 and March 2012, baseline AD visits were made to 217 physicians, 109 (50%) of whom also received follow-up AD. Mean frequency scores for complex behaviors increased significantly, from 2.63 to 2.92, corresponding to a clinically significant 30% increase in the number of respondents who endorsed "almost always" or "always" (P < 0.001). Improvement in mean simple behavior frequency scores was also noted (3.98 vs. 4.13; P = 0.035). Sex and practice type appear to influence reported complex behavior frequency at baseline, whereas only practice type influenced improvement in complex behavior scores at follow up.Conclusions: This study demonstrates the feasibility and potential effectiveness of a low-cost and highly disseminable intervention to improve clinician behavior in the context of treating nicotine dependence in underserved communities.
SN  - 2325-6621
U2  - PMID: 25867533.
DO  - 10.1513/AnnalsATS.201410-466BC
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104824940
T1  - Acute effects of marijuana smoking on negative and positive affect.
AU  - Metrik, Jane
AU  - Kahler, Christopher W
AU  - McGeary, John E
AU  - Monti, Peter M
AU  - Rohsenow, Damaris J
Y1  - 2011///Spring2011
N1  - Accession Number: 104824940. Language: English. Entry Date: 20110422. Revision Date: 20150818. Publication Type: Journal Article; clinical trial; research; tables/charts. Journal Subset: Biomedical; Double Blind Peer Reviewed; Peer Reviewed; USA. Special Interest: Psychiatry/Psychology. Instrumentation: Profile of Mood States (POMS); Marijuana Effect Expectancy Questionnaire (MEEQ) (Schafer and Brown); Time-Line Follow-Back (TLFB) (Dennis et al); Marijuana History and Smoking Questionnaire (Metrik et al); Structured Clinical Interview for DSM-IV Nonpatient Edition (SCID-IV) (First et al); ARCI-Marijuana Scale (ARCI) (Chait et al); Marijuana Withdrawal Checklist. Grant Information: Supported by a grant R01 DA021403 from the National Institute on Drug Abuse, a Research Career Development Award from the Medical Research Service of the Department of Veteran Affairs, and Senior Research Career Scientist awards. NLM UID: 8806397. 
KW  - Affect -- Drug Effects
KW  - Cannabis
KW  - Smoking -- Psychosocial Factors
KW  - Adolescence
KW  - Adult
KW  - Analysis of Covariance
KW  - Analysis of Variance
KW  - Arousal -- Physiology
KW  - Carbon Monoxide -- Analysis
KW  - Checklists
KW  - Chi Square Test
KW  - Clinical Trials
KW  - Descriptive Statistics
KW  - Female
KW  - Funding Source
KW  - Heart Rate -- Physiology
KW  - Human
KW  - Interview Guides
KW  - Male
KW  - Multiple Regression
KW  - Psychological Tests
KW  - Questionnaires
KW  - Repeated Measures
KW  - Scales
KW  - Self Report
SP  - 31
EP  - 46 16p
JO  - Journal of Cognitive Psychotherapy
JF  - Journal of Cognitive Psychotherapy
JA  - J COGNIT PSYCHOTHER
VL  - 25
IS  - 1
CY  - New York, New York
PB  - Springer Publishing Company, Inc.
AB  - Human studies and animal experiments present a complex and often contradictory picture of the acute impact of marijuana on emotions. The few human studies specifically examining changes in negative affect find either increases or reductions following delta-9-tetrahydrocannabinol (THC) administration. In a 2 3 2, instructional set (told THC vs. told no THC) by drug administration (smoked marijuana with 2.8% THC vs. placebo) between-subjects design, we examined the pharmacologic effect of marijuana on physiological and subjective stimulation, subjective intoxication, and self-reported negative and positive affect with 114 weekly marijuana smokers. Individuals were first tested under a baseline/no smoking condition and again under experimental condition. Relative to placebo, THC significantly increased arousal and confusion/bewilderment. However, the direction of effect on anxiety varied depending on instructional set: Anxiety increased after THC for those told placebo but decreased among other participants. Furthermore, marijuana users who expected more impairment from marijuana displayed more anxiety after smoking active marijuana, whereas those who did not expect the impairment became less anxious after marijuana. Both pharmacologic and stimulus expectancy main effects significantly increased positive affect. Frequent marijuana users were less anxious after smoking as compared to less frequent smokers. These findings show that expectancy instructions and pharmacology play independent roles in effects of marijuana on negative affect. Further studies examining how other individual difference factors impact marijuana's effects on mood are needed.
SN  - 0889-8391
AD  - Center for Alcohol and Addiction Studies, Brown University, Providence VA Medical Center
DO  - 10.1891/0889-8391.25.1.31
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105916021
T1  - Acute risk of drug-related death among newly released prisoners in England and Wales.
AU  - Farrell M
AU  - Marsden J
Y1  - 2008/02//
N1  - Accession Number: 105916021. Language: English. Entry Date: 20080516. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Commentary: Darke S. Commentary. From the can to the coffin: deaths among recently released prisoners. (ADDICTION) Feb2008; 103 (2): 256-257. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology. NLM UID: 9304118. 
KW  - Overdose -- Mortality
KW  - Overdose -- Risk Factors
KW  - Prisoners -- Psychosocial Factors
KW  - Substance Abuse -- Mortality
KW  - Adolescence
KW  - Adult
KW  - Coding
KW  - Confidence Intervals
KW  - Data Analysis Software
KW  - Descriptive Statistics
KW  - England
KW  - Female
KW  - International Classification of Diseases
KW  - Male
KW  - Narcotics -- Adverse Effects
KW  - Odds Ratio
KW  - Record Review
KW  - Sex Factors
KW  - Wales
KW  - Human
SP  - 251
EP  - 255 5p
JO  - Addiction
JF  - Addiction
JA  - ADDICTION
VL  - 103
IS  - 2
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - AIMS: To investigate drug-related deaths among newly released prisoners in England and Wales. DESIGN: Database linkage study. PARTICIPANTS: National sample of 48,771 male and female sentenced prisoners released during 1998-2000 with all recorded deaths included to November 2003. FINDINGS: There were 442 recorded deaths, of which 261 (59%) were drug-related. In the year following index release, the drug-related mortality rate was 5.2 per 1000 among men and 5.9 per 1000 among women. All-cause mortality in the first and second weeks following release for men was 37 and 26 deaths per 1000 per annum, respectively (95% of which were drug-related). There were 47 and 38 deaths per 1000 per annum, respectively, among women, all of which were drug-related. In the first year after prison release, there were 342 male deaths (45.8 were expected in the general population) and there were 100 female deaths (8.3 expected in the general population). Drug-related deaths were attributed mainly to substance use disorders and drug overdose. Coronial records cited the involvement of opioids in 95% of deaths, benzodiazepines in 20%, cocaine in 14% and tricyclic antidepressants in 10%. Drug-related deaths among men were more likely to involve heroin and deaths among women were more likely to involve benzodiazepines, cocaine and tricyclic antidepressants. CONCLUSIONS: Newly released male and female prisoners are at acute risk of drug-related death. Appropriate prevention measures include overdose awareness education, opioid maintenance pharmacotherapy, planned referral to community-based treatment services and a community overdose-response using opioid antagonists.
SN  - 0965-2140
AD  - National Addiction Centre, Division of Psychological Medicine and Psychiatry Institute of Psychiatry, King's College London, UK
U2  - PMID: 18199304.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107178004
T1  - Addressing nicotine addiction in women: role of the midwife.
AU  - Ward S
Y1  - 1999/01//1999 Jan-Feb
N1  - Accession Number: 107178004. Language: English. Entry Date: 19990401. Revision Date: 20150818. Publication Type: Journal Article; tables/charts. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. NLM UID: 0365647. 
KW  - Smoking
KW  - Substance Dependence
KW  - Nicotine Replacement Therapy
KW  - United States
KW  - Neoplasms -- Mortality -- United States
KW  - Smoking -- Complications
KW  - Breast Feeding
KW  - Substance Dependence -- Diagnosis
KW  - Smoking Cessation
KW  - Smoking -- In Pregnancy
KW  - Bupropion -- Administration and Dosage
KW  - Nurse Midwifery
KW  - Administration, Inhalation
KW  - Chewing Gum
KW  - Nicotine Patch
KW  - Nicotine Replacement Therapy -- Adverse Effects
KW  - Nicotine Replacement Therapy -- Contraindications
KW  - Information Resources
KW  - Pregnancy
KW  - Female
SP  - 3
EP  - 18 16p
JO  - Journal of Nurse-Midwifery
JF  - Journal of Nurse-Midwifery
JA  - J NURSE MIDWIFERY
VL  - 44
IS  - 1
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Smoking is the leading preventable cause of cancer, cardiovascular disease, and other premature deaths among women in the United States. Tobacco use accounts for 10% of perinatal mortality and is 100% preventable. Smoking is now more common among adolescent girls than among boys. Women's health care providers are in an excellent position to intervene in this growing epidemic. This article addresses the health consequences of smoking as well as the social, economic, and emotional toll of cigarette smoking on the woman and her family. The reasons women begin and continue smoking in spite of known risks are examined. The role of the midwife in treating nicotine addiction in women throughout the life span is examined. A theoretical model based on the woman's stage of change is presented as a framework for intervention. Behavioral and pharmacologic treatment recommendations are included. Opportunities for professional activities for community education and advocacy for a tobacco-free society are presented.
SN  - 0091-2182
AD  - Department of Obstetrics and Gynecology, University of Louisville School of Medicine, Louisville, KY 40292
U2  - PMID: 10063220.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104072232
T1  - Adult hippocampal neurogenesis in the pathogenesis of addiction and dual diagnosis disorders.
AU  - Chambers, R Andrew
Y1  - 2013/06//
N1  - Accession Number: 104072232. Language: English. Entry Date: 20140214. Revision Date: 20150710. Publication Type: Journal Article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology. NLM UID: 7513587. 
KW  - Behavior, Addictive -- Diagnosis
KW  - Hippocampus -- Pathology
KW  - Mental Disorders -- Diagnosis
KW  - Cell Differentiation -- Physiology
KW  - Substance Use Disorders -- Diagnosis
KW  - Adult
KW  - Age Factors
KW  - Animals
KW  - Behavior, Addictive -- Epidemiology
KW  - Diagnosis, Dual (Psychiatry)
KW  - Mental Disorders -- Epidemiology
KW  - Neuronal Plasticity -- Physiology
KW  - Substance Use Disorders -- Epidemiology
SP  - 1
EP  - 12 12p
JO  - Drug & Alcohol Dependence
JF  - Drug & Alcohol Dependence
JA  - DRUG ALCOHOL DEPENDENCE
VL  - 130
IS  - 1-3
PB  - Elsevier Science
AB  - BACKGROUND: As knowledge deepens about how new neurons are born, differentiate, and wire into the adult mammalian brain, growing evidence depicts hippocampal neurogenesis as a special form of neuroplasticity that may be impaired across psychiatric disorders. This review provides an integrated-evidence based framework describing a neurogenic basis for addictions and addiction vulnerability in mental illness. METHODS: Basic studies conducted over the last decade examining the effects of addictive drugs on adult neurogenesis and the impact of neurogenic activity on addictive behavior were compiled and integrated with relevant neurocomputational and human studies. RESULTS: While suppression of hippocampal neurogenic proliferation appears to be a universal property of addictive drugs, the pathophysiology of addictions involves neuroadaptative processes within frontal-cortical-striatal motivation circuits that the neurogenic hippocampus regulates via direct projections. States of suppressed neurogenic activity may simultaneously underlie psychiatric and cognitive symptoms, but also confer or signify hippocampal dysfunction that heightens addiction vulnerability in mental illness as a basis for dual diagnosis disorders. CONCLUSIONS: Research on pharmacological, behavioral and experiential strategies that enhance adaptive regulation of hippocampal neurogenesis holds potential in advancing preventative and integrative treatment strategies for addictions and dual diagnosis disorders.
SN  - 0376-8716
AD  - Laboratory for Translational Neuroscience of Dual Diagnosis & Development, Department of Psychiatry, Indiana University School of Medicine, 791 Union Drive, Indianapolis, IN 46202, United States. Electronic address: robchamb@iupui.edu.
U2  - PMID: 23279925.
DO  - 10.1016/j.drugalcdep.2012.12.005
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103906857
T1  - Advancing the pharmacy practice model in a community teaching hospital by expanding student rotations.
AU  - Delgado, Osmel
AU  - Kernan, William P.
AU  - Knoer, Scott J.
Y1  - 2014/11//11/1/2014
N1  - Accession Number: 103906857. Language: English. Entry Date: 20141021. Revision Date: 20150710. Publication Type: Journal Article; research. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Students, Pharmacy
KW  - Student Placement
KW  - Education, Pharmacy
KW  - Human
KW  - Program Implementation
KW  - Descriptive Statistics
KW  - Ohio
KW  - Quality of Health Care
KW  - Medication History
KW  - Patient Discharge Education
KW  - Professional Role
SP  - 1871
EP  - 1876 6p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 71
IS  - 21
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
AB  - Purpose. The implementation, benefits, and outcomes of a layered learner model (LLM) using pharmacy students as pharmacist extenders are described. Summary. In 2011, Cleveland Clinic Florida (CCF) implemented a pharmacy practice model change with the goal of providing all inpatients quality pharmaceutical care while still providing key specialty clinical pharmacy services. An LLM was initiated in which pharmacists supervise pharmacy residents and students in a team format in which students are used as pharmacist extenders. CCF partnered with local and regional colleges of pharmacy to increase the number of advanced pharmacy practice experience student rotations at CCF. Students are given accountability for a specific number of patient beds based on their rotation. They are required to perform medication histories, education on drug indication and adverse effects, discharge counseling, targeted disease counseling, and profile review for drug-related problems for their patients. After the implementation of this model, improvements were observed in Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) scores (58% versus 70%, respectively), pharmacy interventions per patient per day (0.9 versus 1.4, respectively), and bedside medication delivery capture rate (48% versus 65%, respectively). Conclusion. The implementation of an LLM and partnering with local colleges of pharmacy have improved pharmacy practice at CCF by allowing pharmacy students to work as pharmacist extenders in providing comprehensive pharmacy services to many patients who would not otherwise be reached. This approach has improved HCAHPS scores within the “communication of medication” domain, increased overall patient interventions, and allowed expansion of CCF’s discharge prescription program.
SN  - 1079-2082
AD  - Chief Operating Officer, Cleveland Clinic Florida, Weston, FL
AD  - Assistant Director of Pharmacy, Cleveland Clinic Florida, Weston, FL
AD  - Chief Pharmacy Officer, Cleveland Clinic, Cleveland, OH
U2  - PMID: 25320137.
DO  - 10.2146/ajhp130624
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106200286
T1  - Adverse drug reactions (ADRs): a patient perspective on assessment and prevention in primary care.
AU  - Kieve M
Y1  - 2007/08//
N1  - Accession Number: 106200286. Language: English. Entry Date: 20071130. Revision Date: 20150820. Publication Type: Journal Article. Journal Subset: Editorial Board Reviewed; Europe; Expert Peer Reviewed; Health Services Administration; Nursing; Peer Reviewed; UK & Ireland. Special Interest: Patient Safety; Public Health; Quality Assurance. NLM UID: 101182136. 
KW  - Adverse Drug Event
KW  - Primary Health Care -- United Kingdom
KW  - Adverse Drug Event -- In Pregnancy
KW  - Adverse Drug Event -- Prevention and Control
KW  - Depression -- Chemically Induced
KW  - Education, Medical
KW  - Family Practice
KW  - Female
KW  - Fluoxetine -- Adverse Effects
KW  - Iatrogenic Disease
KW  - Isotretinoin -- Adverse Effects
KW  - Nursing Role
KW  - Pharmacy and Pharmacology -- Education
KW  - Pregnancy
KW  - Proton Pump Inhibitors -- Adverse Effects
KW  - Rhabdomyolysis -- Chemically Induced
KW  - Substance Withdrawal, Controlled
KW  - Suicide -- Chemically Induced
KW  - United Kingdom
KW  - Voluntary Reporting
SP  - 221
EP  - 227 7p
JO  - Quality in Primary Care
JF  - Quality in Primary Care
JA  - QUAL PRIM CARE
VL  - 15
IS  - 4
PB  - Radcliffe Publishing
AB  - A British Medical Association (BMA) report Reporting Adverse Drug Reactions, May 2006, estimated that 250 000 people a year are admitted to hospital suffering harmful effects of prescription drugs at a cost to the NHS of about £466 million a year. This is based on a 2004 study of hospital admissions. The BMA report draws attention to a crisis in public health that is largely being ignored and considers how medical education is failing both patients and doctors. The number of patients suffering and deaths due to adverse drug reactions (ADRs), addiction and withdrawal problems is underestimated, often unrecognised and not well reported. Ignoring the problem is costly in financial and human terms. The following paper describes the importance of the patient experience and recommends the need for systematic changes in practice and education of both the profession and the public in the recognition of ADRs. The paper includes recommendations for primary care trusts to be proactive in encouraging professional and patient Yellow Card ADR reporting, and to remind doctors of their moral duty to inform coroners of possible ADRs that may have preceded sudden death, suicide or fatal accidents. The paper concludes by emphasising the need for good practice in monitoring the sideeffects of medicines, in order that patients gain the maximum benefits from their medicines.
SN  - 1479-1072
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105088816
T1  - Adverse drug reactions in older people.
AU  - Tangiisuran B
AU  - Gozzoli MP
AU  - Davies JG
AU  - Rajkumar C
Y1  - 2010/08//
N1  - Accession Number: 105088816. Language: English. Entry Date: 20101005. Revision Date: 20150711. Publication Type: Journal Article; review; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Gerontologic Care. NLM UID: 9114340. 
KW  - Adverse Drug Event -- In Old Age
KW  - Adverse Drug Event -- Classification
KW  - Medication Errors
KW  - Adverse Drug Event -- Risk Factors
KW  - Adverse Drug Event -- Economics
KW  - Aging -- Physiology
KW  - Polypharmacy -- Adverse Effects
KW  - Adverse Drug Event -- Prevention and Control
KW  - Drug Therapy, Computer Assisted
KW  - Pharmacists
KW  - Voluntary Reporting
KW  - Aged
KW  - Adverse Drug Event -- Epidemiology
SP  - 246
EP  - 259 14p
JO  - Reviews in Clinical Gerontology
JF  - Reviews in Clinical Gerontology
JA  - REV CLIN GERONTOL
VL  - 20
IS  - 3
PB  - Cambridge University Press
AB  - Adverse drug reactions (ADR) pose significant health-related problems for the older person. Many studies from around the world report a significant incidence of ADR in general and in elderly people in particular, resulting in an increase in drug-related morbidity and mortality. Older people appear to be particularly at risk of experiencing an ADR due to a range of factors, which include polypharmacy, altered drug pharmacokinetic profiles and pharmacodynamic responses, drug interactions and cognitive problems that increase the risk in this patient group. Certain drug classes, such as hypoglycaemic agents and cardiovascular active medicines, have been identified as common causes of ADR. Many studies suggest that the majority of ADR are preventable, so that several different approaches have been tried in an attempt to limit this problem, such as the use of computerized systems to communicate routine issues of patient care, interventions made by pharmacists, spontaneous reporting and continuous education of health care professionals. Whilst all have been shown to reduce drug-related events, identifying individuals at high risk of developing ADR at the point of prescribing by using a risk stratification model could improve the identification and prevention of ADR. This article discusses the clinical impact of ADR in older people and the relative merits of the various approaches tested to date before suggesting areas that require further research.
SN  - 0959-2598
AD  - Department of Medicine, Brighton and Sussex Medical School, University of Sussex, Falmer, UK
DO  - 10.1017/S0959259810000171
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105088816&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104614477
T1  - Alcohol attitudes and behaviors among faculty at U.S. schools and colleges of pharmacy.
AU  - Schlesselman, Lauren S.
AU  - Nobre, Carmen
AU  - English, Clayton D.
Y1  - 2011/10//
N1  - Accession Number: 104614477. Language: English. Entry Date: 20120223. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. Instrumentation: Alcohol Use Disorders Identification Test (AUDIT). 
KW  - Faculty, Health Occupations
KW  - Faculty Attitudes -- Evaluation
KW  - Alcohol Drinking -- Evaluation
KW  - Education, Pharmacy
KW  - Faculty-Student Relations
KW  - Human
KW  - Survey Research
KW  - Clinical Assessment Tools
KW  - Alcohol Abuse -- Prevention and Control
KW  - Students, Pharmacy
KW  - Questionnaires
KW  - United States
KW  - Chi Square Test
KW  - Adult
KW  - Middle Age
KW  - Aged
KW  - Male
KW  - Female
KW  - Organizational Policies
KW  - Social Behavior
SP  - 236
EP  - 241 6p
JO  - Pharmacy Practice (18863655)
JF  - Pharmacy Practice (18863655)
JA  - PHARM PRACT
VL  - 9
IS  - 4
PB  - Centro de Investigaciones y Publicaciones Farmaceuticas S.L.
SN  - 1886-3655
AD  - Assistant Clinical Professor & Director, Office of Assessment & Accreditation, School of Pharmacy, University of Connecticut, Storrs, CT (United States).
AD  - School of Pharmacy, University of Connecticut. Storrs, CT (United States).
AD  - Assistant Professor. Albany College of Pharmacy & Health Sciences. Colchester, VT (United States).
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104614477&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104218439
T1  - Alcohol education and training in pre-registration nursing: A national survey to determine curriculum content in the United Kingdom (UK)
AU  - Holloway, Aisha S.
AU  - Webster, Brian J.
Y1  - 2013/09//
N1  - Accession Number: 104218439. Language: English. Entry Date: 20131011. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Core Nursing; Europe; Nursing; Peer Reviewed; UK & Ireland. Special Interest: Nursing Education. NLM UID: 8511379. 
KW  - Alcohol Abuse -- Education -- United Kingdom
KW  - Education, Nursing -- United Kingdom
KW  - Human
KW  - United Kingdom
KW  - Descriptive Research
KW  - Descriptive Statistics
KW  - Convenience Sample
KW  - Questionnaires
KW  - Colleges and Universities
KW  - Student Attitudes -- Evaluation
KW  - Curriculum
SP  - 992
EP  - 997 6p
JO  - Nurse Education Today
JF  - Nurse Education Today
JA  - NURSE EDUC TODAY
VL  - 33
IS  - 9
CY  - New York, New York
PB  - Elsevier Science
AB  - Summary: Background: Alcohol-related harm impacts significantly on the health of the population. Nurses are often among the first health professionals that many patients with alcohol-related problems come into contact with and have been identified as playing a key role but may be ill-prepared to respond. Future nurses need to have the skills, knowledge and clinical confidence to respond to patients suffering from alcohol-related harm. A pre-registration curriculum that ensures a nursing workforce fit for practice in responding to alcohol-related harm is necessary. Objectives: To determine the level of alcohol education and training content in the pre-registration curriculum for nursing in the United Kingdom (UK). To establish whether there are variations in the pre-registration curriculum content across the UK. Design: A descriptive study. Setting: All 68 UK Higher Education Institutions offering a total of 111 pre-registration courses for nurses were invited to participate in the study. Participants: Twenty nine completed questionnaires were returned, a response rate of 26%. The largest number of identified responders were from England (n=15), with 3 from Scotland and 1 each from Wales and Northern Ireland. Nine Universities chose not to identify themselves. Methods: An online semi-structured questionnaire survey was used to collect the study data. Results: Teaching of alcohol and alcohol related harm was mainly delivered during the second year of a pre-registration nursing programme provided mainly to adult and mental health students. Overall, the majority of alcohol related content that is provided within the responding pre-registration nursing courses relates to biophysiology, aetiology, and pharmacological and non-pharmacological interventions. Conclusion: This study highlights the need for a greater and more relevant focus of alcohol education to pre-registration nursing students of all fields of practice incorporating an integrated approach across all years of study.
SN  - 0260-6917
AD  - School of Health in Social Sciences, The University of Edinburgh, The Medical School, Teviot Place, Edinburgh EH8 9AG, UK
AD  - School of Nursing & Midwifery, Faculty of Health & Social Care, Robert Gordon University, Garthdee Campus, Garthdee Road, Aberdeen AB10 7QG, Scotland, UK
U2  - PMID: 23154151.
DO  - 10.1016/j.nedt.2012.10.011
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104218439&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104038351
T1  - Alcohol intoxication alters cognitive skills mediated by frontal and temporal brain regions.
AU  - Magrys, S A
AU  - Olmstead, M C
Y1  - 2014/03//
N1  - Accession Number: 104038351. Language: English. Entry Date: 20141114. Revision Date: 20150710. Publication Type: Journal Article; research. Journal Subset: Biomedical; Double Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 8218014. 
KW  - Alcoholic Intoxication -- Psychosocial Factors
KW  - Attention -- Drug Effects
KW  - Cognition -- Drug Effects
KW  - Ethanol
KW  - Behavior
KW  - Memory -- Drug Effects
KW  - Adult
KW  - Female
KW  - Frontal Lobe -- Drug Effects
KW  - Human
KW  - Male
KW  - Sex Factors
KW  - Temporal Lobe -- Drug Effects
KW  - Young Adult
SP  - 271
EP  - 276 6p
JO  - Brain & Cognition
JF  - Brain & Cognition
JA  - BRAIN COGNIT
VL  - 85
CY  - Burlington, Massachusetts
PB  - Academic Press Inc.
AB  - Alcohol intoxication affects frontal and temporal brain areas and may functionally impair cognitive processes mediated by these regions. This study examined this hypothesis by testing the effects of alcohol on sustained attention, impulsivity, and verbal memory. Sober and placebo control groups were used to distinguish pharmacological from expectancy effects of alcohol. One hundred nine university students were assigned to an alcohol (low, medium, or high dose), placebo or sober group. Moderate and high doses of alcohol impaired all cognitive measures. A gender effect was revealed in that alcohol impaired sustained attention in males, but not females. Both sustained attention and verbal memory exhibited a U-shaped pattern, in that the medium-dose alcohol group showed the greatest impairment. This study adds to knowledge about the effects of alcohol intoxication on frontally- and temporally-mediated cognitive function. These findings have specific relevance for heavy-drinking undergraduate populations, particularly in light of the fact that repeated alcohol administration produces persistent changes in brain neurocircuitry.
SN  - 0278-2626
AD  - Department of Psychology, Queen's University, 62 Arch Street, Kingston, ON K7L 3N6, Canada. Electronic address: 7sm47@queensu.ca.
AD  - Department of Psychology, Queen's University, 62 Arch Street, Kingston, ON K7L 3N6, Canada. Electronic address: olmstead@queensu.ca.
U2  - PMID: 24487348.
DO  - 10.1016/j.bandc.2013.12.010
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104038351&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105161255
T1  - ALO-01 (morphine sulfate and naltrexone hydrochloride) extended-release capsules in the treatment of chronic pain of osteoarthritis of the hip or knee: pharmacokinetics, efficacy, and safety.
AU  - Katz N
AU  - Sun S
AU  - Johnson F
AU  - Stauffer J
Y1  - 2010/04//
N1  - Accession Number: 105161255. Language: English. Entry Date: 20100716. Revision Date: 20150711. Publication Type: Journal Article; clinical trial; research. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Pain and Pain Management. NLM UID: 100898657. 
KW  - Analgesics, Opioid -- Administration and Dosage
KW  - Morphine -- Administration and Dosage
KW  - Naltrexone -- Administration and Dosage
KW  - Osteoarthritis, Hip -- Drug Therapy
KW  - Osteoarthritis, Knee -- Drug Therapy
KW  - Adult
KW  - Aged
KW  - Aged, 80 and Over
KW  - Analgesics, Opioid -- Adverse Effects
KW  - Analgesics, Opioid -- Pharmacokinetics
KW  - Chronic Disease -- Drug Therapy
KW  - Crossover Design
KW  - Double-Blind Studies
KW  - Drug Combinations
KW  - Female
KW  - Human
KW  - Male
KW  - Middle Age
KW  - Morphine -- Adverse Effects
KW  - Morphine -- Pharmacokinetics
KW  - Substance Use Disorders -- Drug Therapy
KW  - Substance Use Disorders -- Prevention and Control
KW  - Naltrexone -- Adverse Effects
KW  - Naltrexone -- Pharmacokinetics
KW  - Narcotic Antagonists -- Administration and Dosage
KW  - Narcotic Antagonists -- Adverse Effects
KW  - Narcotic Antagonists -- Pharmacokinetics
KW  - Osteoarthritis, Hip -- Physiopathology
KW  - Osteoarthritis, Knee -- Physiopathology
KW  - Pain Measurement
KW  - Street Drugs -- Pharmacokinetics
KW  - Treatment Outcomes
SP  - 303
EP  - 311 9p
JO  - Journal of Pain
JF  - Journal of Pain
JA  - J PAIN
VL  - 11
IS  - 4
PB  - Churchill Livingstone, Inc.
AB  - ALO-01 (EMBEDA [morphine sulfate and naltrexone hydrochloride] extended-release capsules [King Pharmaceuticals, Inc, Bridgewater, NJ]), indicated for chronic moderate-to-severe pain, is designed to release naltrexone upon tampering (eg, by crushing), reducing morphine-induced subjective effects. This multicenter, randomized, double-blind, crossover study assessed pharmacokinetics, efficacy, and safety of ALO-01 and compared them with extended-release morphine sulfate (ERMS, KADIAN [morphine sulfate extended-release] capsules [Actavis US, Morristown, NJ]) in adults (N = 113) with osteoarthritis pain. Study periods included washout until pain flare (intensity > or =5, 0 to 10; 0 = no pain, 10 = worst pain); dose titration with ERMS (20 to 160mg BID); and randomization to 2 (crossover) 14-day treatment periods with ERMS or ALO-01, separated by 7 days of open-label ERMS. Assessments included pharmacokinetics (morphine, naltrexone), pain scores (0 to 10), Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index; Patient Global Assessment of Medication (1 to 5; poor to excellent). Mean score at pain flare was 7.1. Morphine exposure from both formulations at steady state was similar. Plasma naltrexone concentrations were below limit-of-quantification for most patients and, when present, did not impact pain scores. During treatment, mean pain intensity (day 14: ERMS, 2.4; ALO-01, 2.3, P = .31), WOMAC change-from-baseline (mean pain, physical function, composite scores), and adverse event frequency were similar. ALO-01 and ERMS provided similar relief of osteoarthritis pain. PERSPECTIVE: We present data demonstrating that ALO-01 has steady-state morphine exposure, efficacy, and safety similar to marketed ERMS capsules. Results highlight the potential for morphine in ALO-01 to manage moderate-to-severe osteoarthritis pain, while the sequestered naltrexone does not interfere with efficacy.
SN  - 1526-5900
AD  - Tufts University School of Medicine, Boston, Massachusetts; Analgesic Research, Needham, MA 02494, USA. nkatz@analgesicresearch.com
U2  - PMID: 19944650.
DO  - 10.1016/j.jpain.2009.07.017
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105161255&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105894970
T1  - Alprazolam (Xanax(R)) Use among Southern Youth: Beliefs and Social Norms Concerning Dangerous Rides on 'Handlebars'.
AU  - Peters RJ
AU  - Meshack AF
AU  - Kelder SH
AU  - Webb P
AU  - Smith D
AU  - Garner K
Y1  - 2007/12//
N1  - Accession Number: 105894970. Language: English. Entry Date: 20080418. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Health Promotion/Education; Peer Reviewed; USA. NLM UID: 1300031. 
KW  - Alprazolam
KW  - Attitude to Health
KW  - Social Environment
KW  - Substance Use Disorders -- Epidemiology
KW  - Adolescence
KW  - Adolescent Behavior
KW  - Female
KW  - Male
KW  - Pilot Studies
KW  - Qualitative Studies
KW  - Substance Use Disorders -- Psychosocial Factors
KW  - United States
KW  - Human
SP  - 417
EP  - 428 12p
JO  - Journal of Drug Education
JF  - Journal of Drug Education
JA  - J DRUG EDUC
VL  - 37
IS  - 4
CY  - Thousand Oaks, California
PB  - Sage Publications Inc.
AB  - While the epidemiologic trends concerning alprazolam (Xanax(R)) are unknown, the use of benzodiazepines, in general, has increased in popularity among youth within recent years. To shed light on the drug problem, the current pilot study used a qualitative approach to investigate relevant beliefs, norms, and perceived addiction associated with alprazolam initiation among 46 youth who were attending an inpatient drug treatment program during the spring of 2004. Overwhelmingly, most participants stated that addiction to alprazolam occurs as early as initial consumption. Most youth in the study stated that their friends felt it was normal to use alprazolam. In addition, their control beliefs revealed that if someone wanted to stop it would be difficult because of the widespread use in their communities and family social reinforcement involved with its use. In this study, a majority of students stated that medical professionals such as doctors and pharmacists were the greatest facilitator of alprazolam acquisition. Implications for these results are discussed.
SN  - 0047-2379
AD  - The University of Texas Health Science Center, Houston
U2  - PMID: 18351180.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105894970&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105525991
T1  - An intervention to develop repeat prescribing in community pharmacy.
AU  - Saastamoinen LK
AU  - Klaukka TJ
AU  - Ilomäki J
AU  - Enlund H
Y1  - 2009/06//
N1  - Accession Number: 105525991. Language: English. Entry Date: 20090703. Revision Date: 20150711. Publication Type: Journal Article; clinical trial; research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Grant Information: Association of Finnish Pharmacies. NLM UID: 8704308. 
KW  - Pharmacists
KW  - Pharmacy, Retail
KW  - Prescriptive Authority
KW  - Chi Square Test
KW  - Clinical Trials
KW  - Continuity of Patient Care
KW  - Data Analysis Software
KW  - Female
KW  - Finland
KW  - Fisher's Exact Test
KW  - Funding Source
KW  - Interviews
KW  - Kappa Statistic
KW  - Male
KW  - Physicians
KW  - Random Assignment
KW  - Human
SP  - 261
EP  - 265 5p
JO  - Journal of Clinical Pharmacy & Therapeutics
JF  - Journal of Clinical Pharmacy & Therapeutics
JA  - J CLIN PHARM THER
VL  - 34
IS  - 3
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Background: Lack of review of patients' medications in repeat prescribing is common. This and other problems in repeat prescribing need to be addressed. Community pharmacists could be more proactive in the review of chronic medications. Objective: The purpose of this study was to test the feasibility and effects of pharmacists' interventions in repeat prescribing. Methods: The normal repeat prescribing process used at Kuopio University Pharmacy and in Kuopio Health Services was developed by an intervention which included a pharmacist's interview and the annual medication data of the patient that were both transferred to the prescribing physician. Results: Physicians in the intervention group identified and solved patients' drug-related problems better than was the case in the comparison group with normal repeat prescribing. Over half the patients receiving repeat prescriptions had at least one drug-related problem. The physicians used more information sources to support repeat prescribing in the intervention system. Conclusions: Community pharmacists are able to improve the quality of physician's repeat prescribing by providing vital information.
SN  - 0269-4727
AD  - The Social Insurance Institution, Helsinki, Finland
U2  - PMID: 19646075.
DO  - 10.1111/j.1365-2710.2008.01003.x
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105525991&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 112692484
T1  - Analysis of drug-related problems in three departments of a German University hospital.
AU  - Lenssen, Rebekka
AU  - Heidenreich, Axel
AU  - Schulz, Jörg
AU  - Trautwein, Christian
AU  - Fitzner, Christina
AU  - Jaehde, Ulrich
AU  - Eisert, Albrecht
Y1  - 2016/02//
N1  - Accession Number: 112692484. Language: English. Entry Date: In Process. Revision Date: 20160209. Publication Type: journal article. Journal Subset: Biomedical; Continental Europe; Europe. NLM UID: 101554912. 
SP  - 119
EP  - 126 8p
JO  - International Journal of Clinical Pharmacy
JF  - International Journal of Clinical Pharmacy
JA  - INT J CLIN PHARM
VL  - 38
IS  - 1
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
AB  - Background: During the last decades, pharmaceutical care services have been developed and implemented to optimize drug therapies and ensure medication safety. To investigate the need for pharmaceutical care services, drug-related problems can be measured.Objective: Thus, the aim of this study was to analyse number, type and occurrence of drug-related problems in different clinical departments.Setting: A pharmaceutical care service was established on general wards in Urology, Neurology and Gastroenterology at the University Hospital RWTH Aachen, Germany.Method: For each of a total of 306 patients, a pharmacist conducted an extended medication history, performed medication reconciliation, conducted medication safety checks and if drug-related problems were discovered, gave valid recommendations to the attending healthcare team. Drug-related problems were classified using the APS-Doc system. For statistical analyses, SAS(®) 9.1.3, SAS Institute, Cary NC, USA was applied. The project was approved by the local ethics committee.Main Outcome Measure: Type, occurrence and frequency of DRP in different medical departments.Results: On average, 2.3 drug-related problems per patient were documented for all three departments. Drug-related problems were found in each category of the APS-Doc system. The most pronounced drug-related problems found were drug-drug interactions (34.6 %). 37 % of the identified drug-related problems occurred before hospital admission, 27 % during transitional care, and 36 % on the ward. Subgroup analysis revealed specific drug-related problem patterns for each clinical department. The number of drug-related problems was found to be associated with the number of drugs and age.Conclusion: Drug-related problems frequently occur in all investigated clinical departments. A holistic pharmaceutical care service could be an option to address this issue. In case of limited resources, individual drug-related problem patterns can be used as a basis for a tailored pharmaceutical care service. As number of drugs and age have been shown to be significant risk factors, it is crucial that the healthcare team including the pharmacist pays special attention to elderly patients and those with polymedication.
SN  - 2210-7703
AD  - Department of Urology, University Hospital RWTH Aachen, Pauwelsstr. 30 52074 Aachen Germany
AD  - Department of Neurology, University Hospital RWTH Aachen, Pauwelsstr. 30 52074 Aachen Germany
AD  - Department of Internal Medicine III, Gastroenterology, Metabolic Disorders and Internal Intensive Medicine, University Hospital RWTH Aachen, Pauwelsstr. 30 52074 Aachen Germany
AD  - Department of Medical Statistics, RWTH Aachen University, Pauwelsstr. 30 52074 Aachen Germany
AD  - Institute of Pharmacy, Clinical Pharmacy, University of Bonn, An der Immenburg 4 53121 Bonn Germany
AD  - Hospital Pharmacy, University Hospital RWTH Aachen, Steinbergweg 20 52074 Aachen Germany
U2  - PMID: 26511945.
DO  - 10.1007/s11096-015-0213-1
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=112692484&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105051499
T1  - APhA2010 House of Delegates: Paving the way for the profession's best practices.
AU  - Thomas RA
AU  - Voytilla R
AU  - Knutson AR
Y1  - 2010/07//Jul/Aug2010
N1  - Accession Number: 105051499. Language: English. Entry Date: 20101126. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 101176252. 
KW  - Pharmacists -- Ethical Issues
KW  - Pharmacists -- Legislation and Jurisprudence
KW  - Professional Practice -- Standards
KW  - Professional Role
KW  - Professional Organizations
KW  - Advertising
KW  - Biological Products -- Economics
KW  - Privacy and Confidentiality -- Ethical Issues
KW  - Education, Pharmacy
KW  - Education, Pharmacy -- Standards
KW  - Prescriptions, Drug -- Standards
KW  - Government Regulations
KW  - Health Promotion -- Methods
KW  - Medical Records, Personal
KW  - Medicine
KW  - Genetics -- Methods
KW  - Professional Practice -- Trends
KW  - Substance Use Disorders
KW  - Industry -- Economics
KW  - Industry -- Ethical Issues
KW  - United States
SP  - 450
EP  - 458 9p
JO  - Journal of the American Pharmacists Association: JAPhA
JF  - Journal of the American Pharmacists Association: JAPhA
JA  - J AM PHARM ASSOC
VL  - 50
IS  - 4
CY  - Washington, District of Columbia
PB  - American Pharmacists Association
SN  - 1544-3191
U2  - PMID: 20621859.
DO  - 10.1331/JAPhA.2010.10522
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105051499&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104547275
T1  - Applicability of an adapted medication appropriateness index for detection of drug-related problems in geriatric inpatients.
AU  - Somers A
AU  - Mallet L
AU  - van der Cammen T
AU  - Robays H
AU  - Petrovic M
Y1  - 2012/04//
N1  - Accession Number: 104547275. Language: English. Entry Date: 20120810. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Gerontologic Care. Instrumentation: Medication Appropriateness Index (MAI). NLM UID: 101190325. 
KW  - Drugs, Prescription -- Therapeutic Use
KW  - Hospitalization -- Statistics and Numerical Data
KW  - Inpatients
KW  - Aged
KW  - Aged, 80 and Over
KW  - Clinical Assessment Tools
KW  - Drug Interactions
KW  - Drugs, Prescription -- Administration and Dosage
KW  - Drugs, Prescription -- Adverse Effects
KW  - Female
KW  - Geriatrics
KW  - Human
KW  - Male
KW  - Observer Bias
KW  - Patient Admission
KW  - Pharmacists -- Administration
KW  - Reproducibility of Results
KW  - Retrospective Design
SP  - 101
EP  - 109 9p
JO  - American Journal of Geriatric Pharmacotherapy
JF  - American Journal of Geriatric Pharmacotherapy
JA  - AM J GERIATR PHARMACOTHER
VL  - 10
IS  - 2
CY  - New York, New York
PB  - Elsevier Science
AB  - BACKGROUND: High drug consumption by older patients and the presence of many drug-related problems require careful assessment of drug therapy, for which a structured approach is recommended. OBJECTIVE: The purpose of our study was to evaluate the applicability of an adapted version of the Medication Appropriateness Index (MAI) in 50 geriatric inpatients at the time of admission. METHODS: We reviewed, for 432 prescribed drugs, indication, right choice, dosage, directions, drug-disease interactions, drug-drug interactions, and duration of therapy. In addition, adverse drug reactions were evaluated, resulting in 8 questions per drug. MAI scores were attributed independently by a geriatrician and by a clinical pharmacist, and differences between them were assessed. Furthermore, the relationship between MAI score and drug-related hospital admission was explored. RESULTS: Mean summed MAI scores of 13.7 according to the geriatrician and 13.6 according to the pharmacist were obtained. The highest scores were found for drugs for the central nervous and the urinary tract system; the highest scores per question were detected for right choice, adverse drug reactions, and drug-drug interactions. A good agreement between the scores of the geriatrician and the pharmacist was found: intraclass correlation coefficient was 0.91 and overall [kappa] value was 0.71. A significantly higher MAI score was found for drug-related hospital admissions (P = 0.04 for the geriatrician and P = 0.03 for the pharmacist). CONCLUSIONS: This adapted MAI score seems useful for detection of drug-related problems in geriatric inpatients and reliable with a low inter-rater variability and positive correlation between high score and drug-related hospital admission. We consider further application of the adapted MAI for teaching and training of clinical pharmacists, and as a systematic approach for detection of drug-related problems by the clinical pharmacists in our hospital.
SN  - 1543-5946
AD  - Department of Pharmacy, Ghent University Hospital, Gent, Belgium.
U2  - PMID: 22304791.
DO  - 10.1016/j.amjopharm.2012.01.003
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104547275&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105572814
T1  - Appropriateness of prescribing among elderly patients in a Dutch residential home: observational study of outcomes after a pharmacist-led medication review.
AU  - Stuijt CCM
AU  - Franssen EJF
AU  - Egberts ACG
AU  - Hudson SA
Y1  - 2008/08//
N1  - Accession Number: 105572814. Language: English. Entry Date: 20090220. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Australia & New Zealand; Biomedical; Peer Reviewed. Special Interest: Gerontologic Care. NLM UID: 9102074. 
KW  - Drug Utilization -- Methods
KW  - Pharmacists
KW  - Prescriptions, Drug -- Standards
KW  - Residential Facilities -- Statistics and Numerical Data
KW  - Aged
KW  - Aged, 80 and Over
KW  - Confidence Intervals
KW  - Data Analysis Software
KW  - Data Analysis, Statistical
KW  - Drug Interactions
KW  - Female
KW  - Health Personnel
KW  - Interrater Reliability
KW  - Male
KW  - Netherlands
KW  - Paired T-Tests
KW  - Pharmacy, Retail
KW  - Physicians, Family
KW  - Residential Facilities
KW  - Residential Facilities -- Manpower
KW  - Human
SP  - 947
EP  - 954 8p
JO  - Drugs & Aging
JF  - Drugs & Aging
JA  - DRUGS AGING
VL  - 25
IS  - 11
PB  - Springer Science & Business Media B.V.
AB  - BACKGROUND: Clinically significant pharmacokinetic and pharmacodynamic changes occurring with age make older patients more prone to the consequences of inappropriate prescribing. The combination of higher use of medicines resulting from a higher disease burden with suboptimal treatment monitoring results in a higher risk of unwanted drug effects from sometimes inappropriate choice of drugs, doses and durations of treatment. Pharmacy services are increasingly being targeted to minimize the overall number of unnecessary and potential harmful medicines. OBJECTIVE: To investigate the impact of a pharmacist-led medication review on quality of prescribing by a healthcare professional team consisting of a general practitioner (GP), care home staff and a pharmacist. METHODS: This observational study compared outcome measurements before and after a pharmacist-led review of medications for patients under the care of a healthcare professional team consisting of a GP, care home staff and pharmacist. The procedure for conducting and recording the medication review consisted of the preparation of a patient medication profile, which combined the patient's medical records with his or her complete prescription record (current and previous [last 3 years] medication history) and pharmaceutical record (electronic journal entries for the patient over the same period). Laboratory values were evaluated in clinical context. Recommendations for the pharmaceutical plan were discussed at a conference involving the clinical pharmacist and other healthcare team members. Patients were recruited for medication review over the 12-month period 1 April 2003 to 1 April 2004. Medication appropriateness was assessed by an independent panel of clinical pharmacists using the Medication Appropriateness Index (MAI). RESULTS: A total of 54 patients were eligible according to the inclusion criteria, of whom 24 were subsequently excluded for various reasons; thus, 30 patients were eligible for assessment on the MAI. There was a statistically significant difference between overall pre- and post-intervention summed MAI scores (p = 0.013). The pharmacist identified 115 drug-related problems, and the total number of accepted recommendations was 78 (67.8%). Use of a medication review as an intervention by a clinical pharmacist was associated with an improvement in appropriateness of prescribing. CONCLUSION: This study provides evidence supporting the formal integration of a clinical pharmacist into the healthcare team with the aim of improving prescribing appropriateness for institutionalized elderly Dutch patients. Overall MAI scores for all long-term medications used by a group of elderly patients improved significantly after a pharmacist-led medication review. This is an important finding because quality of prescribing is assuming increasing importance as a means of preventing avoidable medication-related harm.
SN  - 1170-229X
AD  - Department of Pharmacy, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands.
U2  - PMID: 18947262.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105572814&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105787298
T1  - Are nurses prepared to curb the tobacco epidemic in China? A questionnaire survey of schools of nursing.
AU  - Chan SS
AU  - Sarna L
AU  - Danao LL
Y1  - 2008/05//
N1  - Accession Number: 105787298. Language: English. Entry Date: 20080815. Revision Date: 20150820. Publication Type: Journal Article; pictorial; research; tables/charts. Journal Subset: Core Nursing; Europe; Nursing; Peer Reviewed; UK & Ireland. Special Interest: Nursing Education. NLM UID: 0400675. 
KW  - Education, Nursing, Baccalaureate -- China
KW  - Smoking Cessation -- Education -- China
KW  - Smoking -- Prevention and Control -- China
KW  - China
KW  - Convenience Sample
KW  - Cross Sectional Studies
KW  - Curriculum
KW  - Descriptive Research
KW  - Descriptive Statistics
KW  - Hong Kong
KW  - Mail
KW  - Maps
KW  - Questionnaires
KW  - Schools, Nursing
KW  - Smoking -- Epidemiology
KW  - Students, Nursing, Baccalaureate
KW  - Survey Research
KW  - Human
SP  - 706
EP  - 713 8p
JO  - International Journal of Nursing Studies
JF  - International Journal of Nursing Studies
JA  - INT J NURS STUD
VL  - 45
IS  - 5
CY  - Philadelphia, Pennsylvania
PB  - Elsevier Inc.
AB  - BACKGROUND: Smoking prevalence among Chinese males is the highest in the world and its morbidity and mortality is growing. Previous studies suggested nurses are inadequately prepared to treat tobacco use and dependence. OBJECTIVES: To examine the inclusion and organization of tobacco control content in the undergraduate nursing curriculum of Hong Kong and Mainland China; and the smoking status of faculty and students. DESIGN: Cross-sectional survey. METHODS: Deans of 32 nursing schools in Hong Kong and China with an undergraduate programme (representing over 12000 students) completed a self-administered questionnaire. RESULTS: Most schools included the health hazards of tobacco (56.3-100%), but few covered tobacco cessation theory (31.3-62.5%), or behavioural (9.4-56.3%) and pharmacological (3.1-34.4%) interventions in the curriculum. Most curricula covered less than 1h of tobacco content per year of study. Nearly all schools (93.1%) reported smoking among faculty but only half reported access to smoking cessation programmes. CONCLUSIONS: This is the first known study to examine the extent of tobacco control education in the nursing curriculum in China. Results suggested deficiencies in the coverage and clinical practice in smoking and smoking cessation, and recommendations were made to strengthen the curriculum.
SN  - 0020-7489
AD  - Department of Nursing Studies, The University of Hong Kong, Hong Kong SAR, China.
U2  - PMID: 17336307.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105787298&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 112721483
T1  - Are the last grade medical students aware of the danger of synthetic cannabinoids?
AU  - Beyhun, Nazim Ercument
AU  - Can, Gamze
AU  - Topbas, Murat
AU  - Cankaya, Sertac
AU  - Ketenci, Huseyin Cetin
Y1  - 2016/02//
N1  - Accession Number: 112721483. Language: English. Entry Date: In Process. Revision Date: 20160209. Publication Type: journal article. Journal Subset: Biomedical; Europe; UK & Ireland. NLM UID: 101300022. 
SP  - 1
EP  - 5 5p
JO  - Journal of Forensic & Legal Medicine
JF  - Journal of Forensic & Legal Medicine
JA  - J FORENSIC LEGAL MED
VL  - 38
CY  - New York, New York
PB  - Elsevier Science
AB  - Synthetic cannabinoids are drugs which are increasingly used by especially adolescents and young people. In recent years hospital admissions even concluding with deaths have been observed. Therefore, the awareness of medical students, who will be in challenge with this new drug abuse, is an important issue. The aim of this study is to figure out the awareness of the last grade medical students and its correlates. This is a questionnaire based descriptive study with the participation of 148 students at Karadeniz Technical University Medical Faculty, Turkey. An awareness score was produced to measure awareness (cronbach alpha = 0.67). The 17.6% (26/148) of students who reported not knowing what synthetic cannabinoids were and hearing the name for the first time in this study. The 16.4% of students assumed that synthetic cannabinoid use was legal, and 16.2% assumed that synthetic cannabinoids are not drugs. The internet (including social media) (48.6%) and pharmacology lectures (40.5%) were identified as the most stated sources of information. The students who have synthetic cannabinoid user friends and social media account have significantly higher awareness scores (p < 0.05 for both). Last grade medical students have a lack of awareness towards synthetic cannabinoids which is an increasing threat that they have to challenge.
SN  - 1752-928X
AD  - Karadeniz Technical University Medical Faculty, Dep. of Public Health, 61080 Trabzon, Turkey
AD  - Trabzon Branch of The Council of Forensic Medicine, Trabzon, Turkey
U2  - PMID: 26694870.
DO  - 10.1016/j.jflm.2015.11.014
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=112721483&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 114503190
T1  - ASHP professional policy recommendations--Invitation to comment.
Y1  - 2016/04/15/
N1  - Accession Number: 114503190. Language: English. Entry Date: 20160415. Revision Date: 20160415. Publication Type: Article. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Reports
KW  - Policy Making
KW  - Professional Organizations
KW  - Pharmacy and Pharmacology
KW  - Governing Board
KW  - Pharmaceutical Companies
KW  - Drugs, Off-Label
KW  - Drug Approval
KW  - Licensure
KW  - Health Services Accessibility -- Evaluation
KW  - Patient Care
KW  - Home Health Care
KW  - Administration, Intravenous
KW  - United States Food and Drug Administration
KW  - Substance Abuse -- Prevention and Control
KW  - Antipsychotic Agents -- Administration and Dosage
KW  - Safety
KW  - Analgesia, Epidural
KW  - Steroids -- Administration and Dosage
KW  - Injections
KW  - Renal Replacement Therapy -- Methods
KW  - Dosage Calculation
KW  - Education
KW  - Workforce
KW  - Pharmacy Technicians -- Education
KW  - Certification
KW  - Leadership
KW  - Drug and Narcotic Control
KW  - Drug Packaging
KW  - Hazardous Materials
KW  - Medication Systems -- Evaluation
KW  - Automation
KW  - Technology
KW  - Information Technology
KW  - Drug Monitoring -- Methods
KW  - Drug Contamination -- Prevention and Control
SP  - e108
EP  - e112 5p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 73
IS  - 8
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
SN  - 1079-2082
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=114503190&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104015991
T1  - ASHP Statement on the Pharmacist's Role in Substance Abuse Prevention, Education, and Assistance.
Y1  - 2014/02//2/1/2014
N1  - Accession Number: 104015991. Language: English. Entry Date: 20140131. Revision Date: 20150710. Publication Type: Journal Article. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Pharmacists
KW  - Professional Role
KW  - Substance Abuse -- Prevention and Control
KW  - Pharmacy Service -- Organizations
KW  - Accountability
KW  - Education
SP  - 243
EP  - 246 4p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 71
IS  - 3
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
SN  - 1079-2082
U2  - PMID: 24429020.
DO  - 10.2146/sp140002
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104015991&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103906322
T1  - ASHP Statement on the Pharmacist's Role in Substance Abuse Prevention, Education, and Assistance.
Y1  - 2014/01//2014/2015
N1  - Accession Number: 103906322. Language: English. Entry Date: 20141028. Revision Date: 20150710. Publication Type: Journal Article. Journal Subset: Biomedical; USA. NLM UID: 101244593. 
KW  - Pharmacists
KW  - Professional Role -- Evaluation
KW  - Substance Abuse -- Prevention and Control
KW  - Allied Health Organizations -- Standards
KW  - Substance Abuse -- Education
KW  - Patient Education
KW  - Collaboration
KW  - Support, Psychosocial
SP  - 305
EP  - 308 4p
JO  - Best Practices for Hospital & Health-System Pharmacy
JF  - Best Practices for Hospital & Health-System Pharmacy
JA  - BEST PRACT HOSP HEALTH SYST PHARM
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
SN  - 1555-8975
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103906322&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103906210
T1  - ASHP Statement on the Pharmacist's Role in Substance Abuse Prevention, Education, and Assistance.
Y1  - 2013/01//2013/2014
N1  - Accession Number: 103906210. Language: English. Entry Date: 20141028. Revision Date: 20150710. Publication Type: Journal Article. Journal Subset: Biomedical; USA. NLM UID: 101244593. 
KW  - Professional Organizations
KW  - Practice Guidelines
KW  - Pharmacists -- Evaluation
KW  - Substance Abuse -- Prevention and Control
KW  - Education
KW  - Patient Care
KW  - Pharmacy and Pharmacology
KW  - Patient Assessment -- Methods
KW  - Patient Education
KW  - Prescribing Patterns
KW  - Collaboration
SP  - 294
EP  - 297 4p
JO  - Best Practices for Hospital & Health-System Pharmacy
JF  - Best Practices for Hospital & Health-System Pharmacy
JA  - BEST PRACT HOSP HEALTH SYST PHARM
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
SN  - 1555-8975
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103906210&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105972264
T1  - ASHP statement on the pharmacist's role in substance abuse prevention, education, and assistance.
Y1  - 1998/08/15/1998 Aug 15
N1  - Accession Number: 105972264. Language: English. Entry Date: 20080215. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Health Education -- Trends
KW  - Pharmacists
KW  - Substance Use Disorders -- Prevention and Control
KW  - Professional Organizations
KW  - United States
SP  - 1721
EP  - 1724 4p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 55
IS  - 16
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
SN  - 1079-2082
U2  - PMID: 9740911.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105972264&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106543745
T1  - ASHP statement on the pharmacist's role in substance abuse prevention, education, and assistance.
Y1  - 2003/10//10/1/2003
N1  - Accession Number: 106543745. Corporate Author: American Society of Health-Systems Pharmacists. Language: English. Entry Date: 20081219. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Pharmacists
KW  - Substance Abuse -- Prevention and Control
KW  - Professional Role
SP  - 1995
EP  - 1998 4p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 60
IS  - 19
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
SN  - 1079-2082
U2  - PMID: 14531247.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106543745&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104051872
T1  - Assessing Student Pharmacists' Ability to Identify Drug-Related Problems in Patients Within a Patient-Centered Medical Home.
AU  - Armor, Becky L.
AU  - Bulkley, Christina F.
AU  - Truong, Teresa
AU  - Carter, Sandra M.
Y1  - 2014/01//
N1  - Accession Number: 104051872. Language: English. Entry Date: 20140328. Revision Date: 20150710. Publication Type: Journal Article. Journal Subset: Biomedical; USA. 
SP  - 1
EP  - 6 6p
JO  - American Journal of Pharmaceutical Education
JF  - American Journal of Pharmaceutical Education
JA  - AM J PHARMACEUTICAL EDUC
VL  - 78
IS  - 1
CY  - Alexandria, Virginia
PB  - American Association of Colleges of Pharmacy
SN  - 0002-9459
AD  - University of Oklahoma College of Pharmacy, Oklahoma City, Oklahoma
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104051872&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107316855
T1  - Assessing substance abuse among health care students and the efficacy of educational interventions.
AU  - Coleman EA
AU  - Honeycutt G
AU  - Ogden B
AU  - McMillan DE
AU  - O'Sullivan PS
AU  - Light K
AU  - Wingfield W
Y1  - 1997/01//1997 Jan-Feb
N1  - Accession Number: 107316855. Language: English. Entry Date: 19970401. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Nursing; Peer Reviewed; USA. Instrumentation: Standardized Substance Abuse Attitude Survey (SSAAS). Grant Information: US Department of Education, FIPSE Drug Prevention Programs Award No. P183A90290. NLM UID: 8511298. 
KW  - Substance Abuse -- Education
KW  - Students, Health Occupations
KW  - Substance Abuse -- Prevention and Control
KW  - Attitude Measures
KW  - Convenience Sample
KW  - Students, Nursing
KW  - Students, Pharmacy
KW  - Colleges and Universities -- Arkansas
KW  - Arkansas
KW  - Surveys
KW  - Curriculum
KW  - Student Attitudes -- Evaluation
KW  - Summated Rating Scaling
KW  - Descriptive Statistics
KW  - Chi Square Test
KW  - Descriptive Research
KW  - Prospective Studies
KW  - Funding Source
KW  - Human
SP  - 28
EP  - 37 10p
JO  - Journal of Professional Nursing
JF  - Journal of Professional Nursing
JA  - J PROF NURS
VL  - 13
IS  - 1
CY  - Philadelphia, Pennsylvania
PB  - W B Saunders
AB  - Approximately 10 per cent of nurses are chemically dependent, and, for many, substance abuse begins while attending nursing school. Faculty must be able to assess the extent of the problem, understand the contributing factors, recognize signs and symptoms, and use educational interventions in identifying and preventing chemical dependency in nurses. Beginning in 1989, the authors sampled all entering students in four colleges on a health science campus using the Standardized Substance Abuse Attitude Survey and obtained resurvey data from two of the colleges' 1989 entering classes in fall 1991. Each college developed educational interventions. Some clear differences between nursing and pharmacy students emerged and indicated that a greater emphasis on drug and alcohol education can pay dividends. Establishing a data base over a period of more than 2 years provides a foundation to evaluate further interventions. Copyright (c) 1997 by W.B. Saunders Company
SN  - 8755-7223
AD  - College of Nursing, University of Arkansas for Medical Sciences, 4301 W Markham St, Slot 529, Little Rock, AR 77205
U2  - PMID: 9183110.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107316855&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107218095
T1  - Assessment of drug-related problems in clinical nutrition patients.
AU  - Cerulli J
AU  - Malone M
Y1  - 1999/07//
N1  - Accession Number: 107218095. Language: English. Entry Date: 19991001. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Allied Health; Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7804134. 
KW  - Drug Interactions
KW  - Enteral Nutrition
KW  - Parenteral Nutrition
KW  - Drugs -- Adverse Effects
KW  - Human
SP  - 218
EP  - 221 4p
JO  - JPEN Journal of Parenteral & Enteral Nutrition
JF  - JPEN Journal of Parenteral & Enteral Nutrition
JA  - JPEN J PARENTER ENTERAL NUTR
VL  - 23
IS  - 4
CY  - Thousand Oaks, California
PB  - Sage Publications Inc.
AB  - BACKGROUND: Medication use in clinical nutrition patients is affected by concomitant disease states and alterations in medication administration and delivery. The purpose of this evaluation was to document the number and type of drug-related problems that occurred and to evaluate the effect pharmacists had on the care of nutrition patients. METHODS: Patients were evaluated by a pharmacist who was part of the clinical nutrition team. Drug-related problems were identified and recommendations were made to resolve them. Acceptance of the recommendations and patient outcomes were documented. RESULTS: After the evaluation of 440 patients, 220 pharmacist interventions were made. Interventions included 35 drug information requests and 185 recommendations made to solve identified drug-related problems in 126 patients. The most frequent drug-related problems were drug interactions (33/185) and untreated indications (24/185). Of 185 recommendations, 166 were accepted, and 19 were accepted with a modification. A total of 132 of 155 recommendations that were accepted or accepted with modification had a positive outcome: 45 patients responded, and 87 patients developed no complications. Six patients did not respond to the recommendation, and in 17 patients the outcome was unknown. Fifty-eight recommendations avoided potential adverse drug events. CONCLUSIONS: Pharmacist intervention identified drug-related problems in almost 30% of clinical nutrition patients. The identification and resolution of the problems had a positive effect on patient care, as indicated by patient outcome and the avoidance of adverse drug events. The drug-related problem approach identified areas in which pharmacists can educate the health care team and ensure proper medication use in this patient population.
SN  - 0148-6071
AD  - Division of Pharmacy Practice, Albany College of Pharmacy, 106 New Scotland Avenue, Albany, NY 12208-3492
U2  - PMID: 10421391.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107218095&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104797891
T1  - Associations between work stress, alcohol consumption and sickness absence.
AU  - Vasse, R M
AU  - Nijhuis, F J
AU  - Kok, G
Y1  - 1998/02//
N1  - Accession Number: 104797891. Language: English. Entry Date: 20110610. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9304118. 
KW  - Absenteeism
KW  - Alcohol Drinking
KW  - Occupational Diseases -- Psychosocial Factors
KW  - Stress, Psychological -- Etiology
KW  - Adult
KW  - Alcohol Drinking -- Epidemiology
KW  - Cross Sectional Studies
KW  - Female
KW  - Health Status
KW  - Human
KW  - Male
KW  - Middle Age
KW  - Netherlands
KW  - Occupational Diseases -- Epidemiology
KW  - Prevalence
KW  - Sick Leave
KW  - Smoking -- Epidemiology
KW  - Stress, Psychological -- Epidemiology
SP  - 231
EP  - 241 11p
JO  - Addiction
JF  - Addiction
JA  - ADDICTION
VL  - 93
IS  - 2
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - To test an interactional model on the associations between work stressors, perceived stress, alcohol consumption and sickness absence. Cross-sectional survey. The study was part of a Worksite Health Project including an Employee Assistance Programme and a Health Promotion Programme in the Netherlands. Participants were blue-collar workers from two Municipal Garbage Collecting Departments and white-collar workers from a Pharmaceutical Company (N = 471). Measurements included socio-demographic characteristics (gender, age, education, marital status), work stressors, perceived stress, alcohol consumption and sickness absence. Type of work-site (blue- or white-collar) and smoking behaviour were used as covariates. Regression analyses resulted in three major findings. First, in the presence of stress, abstinence increased the risk of sickness absence compared with moderate drinking. We failed to find a significant relationship between excessive drinking and sickness absence. Secondly, stress mediated the associations between stressor and alcohol consumption, and between stressor and sickness absence, although stressors also directly predicted sickness absence. The association between abstinence and sickness absence could reflect medical problems of abstainers or a lack of skills for coping with stress. The failure to find a significant detrimental effect of excessive drinking may have been due to use of a low threshold for excessive drinking and/or low power. Prospective studies are needed to gain insight in causal relationships between the variables concerned.
SN  - 0965-2140
AD  - Department of Health Education and Promotion, University of Maastricht, The Netherlands. r.vasse@gvo.unimaas.nl
U2  - PMID: 9624724.
DO  - 10.1046/j.1360-0443.1998.9322317.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106682277
T1  - Attention-deficit/hyperactivity disorder and the substance use disorders: the nature of the relationship, who is at risk, and treatment issues.
AU  - Wilens TE
Y1  - 2004/07//2004 Jul
N1  - Accession Number: 106682277. Language: English. Entry Date: 20040827. Revision Date: 20150711. Publication Type: Journal Article; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9602353. 
KW  - Attention Deficit Hyperactivity Disorder -- Therapy
KW  - Substance Abuse -- Risk Factors
KW  - Comorbidity
KW  - Methylphenidate -- Therapeutic Use
KW  - Patient Education
KW  - Psychotherapy
SP  - 63
EP  - 70 8p
JO  - Primary Psychiatry
JF  - Primary Psychiatry
JA  - PRIM PSYCHIATRY
VL  - 11
IS  - 7
CY  - New York, New York
PB  - MBL Communications
AB  - There is much interest in the overlap between attention-deficit/hyperactivity disorder (ADHD) and substance use disorders (SUD). Various studies have shown that ADHD is a risk factor for the development of SUD in adulthood and that approximately one fifth of adults with SUD have ADHD. The reason for this association is unclear. One suggestion is that stimulant therapy for ADHD may at least contribute to the increased risk of SUD in individuals with ADHD. This belief has, however, been disproved in a meta-analysis of five prospective longitudinal studies and one retrospective study of subjects with ADHD, which found that the risk of SUD was significantly reduced in subjects receiving stimulant therapy compared to unmedicated subjects. Management of adults with ADHD and comorbid SUD should be multimodal, involving education, psychosocial therapy, and pharmacotherapy. While education and psychosocial therapy can reduce craving and help patients live with the symptoms of ADHD, pharmacotherapy is required to bring the core symptoms of ADHD under control. The use of long-acting stimulants, such as OROS methylphenidate (MPH), is particularly appropriate in such patients since their long duration of action means that medication can be kept at home, thus reducing opportunities for diversion. In addition, attempts at intranasal abuse of OROS MPH have been reported to fail, suggesting that the formulation of MPH in the tablet is not accessible for abuse. Nonstimulants, such as bupropion, venlafaxine, and atomoxetine, are alternative anti-ADHD therapies for patients who do not respond to stimulants; they may also reduce craving.
SN  - 1082-6319
AD  - ACC 725, Pediatric Psychopharmacology Research Unit, Massachusetts General Hospital, Harvard Medical School, 15 Parkman St, Boston, MA 02114; TWilens@partners.org
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106682277&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105450242
T1  - Attention-deficit/hyperactivity disorder in children and adolescents: closing diagnostic, communication, and treatment gaps.
AU  - Vierhile A
AU  - Robb A
AU  - Ryan-Krause P
Y1  - 2009/01/02/Jan2009 Supplement
N1  - Accession Number: 105450242. Language: English. Entry Date: 20090417. Revision Date: 20150819. Publication Type: Journal Article; algorithm; CEU; tables/charts. Supplement Title: Jan2009 Supplement. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Special Interest: Advanced Nursing Practice; Pediatric Care. NLM UID: 8709735. 
KW  - Attention Deficit Hyperactivity Disorder -- Diagnosis
KW  - Attention Deficit Hyperactivity Disorder -- Therapy
KW  - Academic Performance
KW  - Adolescence
KW  - Amphetamines -- Adverse Effects
KW  - Amphetamines -- Therapeutic Use
KW  - Atomoxetine -- Therapeutic Use
KW  - Attention Deficit Hyperactivity Disorder -- Drug Therapy
KW  - Attention Deficit Hyperactivity Disorder -- Economics
KW  - Attention Deficit Hyperactivity Disorder -- Education
KW  - Attention Deficit Hyperactivity Disorder -- Epidemiology -- United States
KW  - Attention Deficit Hyperactivity Disorder -- Ethnology
KW  - Attention Deficit Hyperactivity Disorder -- Nursing
KW  - Attention Deficit Hyperactivity Disorder -- Prevention and Control
KW  - Attention Deficit Hyperactivity Disorder -- Symptoms
KW  - Behavior Rating Scales
KW  - Behavior Therapy
KW  - Bupropion -- Therapeutic Use
KW  - Child
KW  - Child, Preschool
KW  - Combined Modality Therapy
KW  - Communication
KW  - Education, Continuing (Credit)
KW  - Ethnic Groups
KW  - Female
KW  - Health Screening
KW  - Interviews
KW  - Male
KW  - Medication Compliance
KW  - Methylphenidate -- Therapeutic Use
KW  - Parents -- Education
KW  - Patient History Taking
KW  - Pediatric Nurse Practitioners
KW  - Substance Abuse -- Risk Factors
KW  - United States
SP  - S5
EP  - 23 1p
JO  - Journal of Pediatric Healthcare
JF  - Journal of Pediatric Healthcare
JA  - J PEDIATR HEALTH CARE
VL  - 23
IS  - 1
CY  - New York, New York
PB  - Elsevier Science
AB  - Nurses and nurse practitioners often play a key role in the management of children with attention-deficit/hyperactivity disorder (ADHD), a disorder that often persists into adolescence and adulthood. The diagnosis of ADHD requires careful history taking, use of standardized rating scales, and close attention to the patient's behavior and informants' reports. Stimulants appear to be most effective for patients with this diagnosis, but pharmacotherapy for ADHD should be combined with educational and behavioral interventions and careful follow-up to optimize treatment outcomes. Nurses and nurse practitioners must advocate to assist patients and families achieve goals at home and at school.
SN  - 0891-5245
AD  - University of Rochester, Pediatric Nursing, 601 Elmwood Ave, Rochester, NY 14642, amy_vierhile@urmc.rochester.edu
U2  - PMID: 19084757.
DO  - 10.1016/j.pedhc.2008.10.009
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105450242&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105819408
T1  - Automated system for identifying potential dosage problems at a large university hospital.
AU  - McMullin ST
AU  - Reichley RM
AU  - Kahn MG
AU  - Dunagan WC
AU  - Bailey TC
Y1  - 1997/03//1997 Mar 1
N1  - Accession Number: 105819408. Language: English. Entry Date: 20080307. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Clinical Pharmacy Information Systems
KW  - Drug Therapy, Computer Assisted -- Standards
KW  - Medication Errors
KW  - Adolescence
KW  - Adult
KW  - Aged
KW  - Aged, 80 and Over
KW  - Chemistry, Pharmaceutical
KW  - Kidney Diseases -- Metabolism
KW  - Kidney -- Metabolism
KW  - Middle Age
KW  - Pharmacy Service -- Administration
KW  - Prescriptions, Drug
KW  - Software
SP  - 545
EP  - 549 5p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 54
IS  - 5
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
AB  - A hospital's experience with an automated system for screening drug orders for potential dosage problems is described. DoseChecker was developed by the hospital pharmacy department in collaboration with a local university. Pharmacy, laboratory, and patient demographic data are transferred nightly from the hospital's mainframe system to a database server; DoseChecker uses these data and user-defined rules to (1) identify patients receiving any of 35 targeted medications, (2) evaluate the appropriateness of current dosages, and (3) generate alerts for patients potentially needing dosage adjustments. The alert reports are distributed to satellite pharmacists, who evaluate each patient's condition and make recommendations to physicians as needed. One of the system's primary purposes is to calculate creatinine clearance and verify that dosages are properly adjusted for renal function. Between May and October 1995, the system electronically screened 28,528 drug orders and detected potential dosage problems in 2859 (10%). The system recommended a lower daily dose in 1992 cases (70%) and a higher daily dose in 867 (30%). Pharmacists contacted physicians concerning 1163 (41%) of the 2859 alerts; in 868 cases (75%), the physicians agreed to adjust the dosage. The most common dosage problem identified was failure to adjust dosages on the basis of declining renal function. An automated system provided an efficient method of identifying inappropriate dosages at a large university hospital.
SN  - 1079-2082
AD  - Department of Pharmacy, Barnes-Jewish Hospital, St. Louis, MO 63110, USA.
U2  - PMID: 9066863.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105819408&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104593929
T1  - Behavioral Pharmacogenetic Analysis on the Role of the α4 GABAA Receptor Subunit in the Ethanol-Mediated Impairment of Hippocampus-Dependent Contextual Learning.
AU  - Cushman, Jesse D.
AU  - Moore, Melissa D.
AU  - Jacobs, Nate S.
AU  - Olsen, Richard W.
AU  - Fanselow, Michael S.
Y1  - 2011/11//
N1  - Accession Number: 104593929. Language: English. Entry Date: 20111211. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Psychiatry/Psychology. Grant Information: Support: NIH grants: AA07680 and NS35985; Training grants: 5T32MH019384-14 and T32 MH019384-14.. NLM UID: 7707242. 
KW  - Ethanol -- Adverse Effects
KW  - Hippocampus -- Drug Effects
KW  - Learning -- Drug Effects
KW  - Cognition -- Drug Effects
KW  - Research Methodology
KW  - Receptors, Cell Surface -- Drug Effects
KW  - High-Throughput Screening Assays
KW  - Ethanol -- Administration and Dosage
KW  - Steroids -- Administration and Dosage
KW  - Mice
KW  - Animal Studies
KW  - Videorecording
KW  - Locomotion -- Evaluation
KW  - Data Analysis Software
KW  - Analysis of Variance
KW  - Post Hoc Analysis
KW  - Repeated Measures
KW  - Two-Way Analysis of Variance
KW  - Task Performance and Analysis
KW  - Conditioning (Psychology)
KW  - Fear
KW  - Funding Source
SP  - 1948
EP  - 1959 12p
JO  - Alcoholism: Clinical & Experimental Research
JF  - Alcoholism: Clinical & Experimental Research
JA  - ALCOHOLISM
VL  - 35
IS  - 11
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 0145-6008
AD  - From the Department of Psychology and Brain Research Institute (JDC, NSJ, MSF), University of California, Los Angeles, California; and Department of Molecular and Medical Pharmacology (MDM, RWO), Geffen School of Medicine, University of California, Los Angeles, California.
DO  - 10.1111/j.1530-0277.2011.01546.x
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104593929&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104317269
T1  - Behavioral, biological, and chemical perspectives on targeting CRF(1) receptor antagonists to treat alcoholism.
AU  - Zorrilla, Eric P
AU  - Heilig, Markus
AU  - de Wit, Harriet
AU  - Shaham, Yavin
Y1  - 2013/03//
N1  - Accession Number: 104317269. Language: English. Entry Date: 20130816. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology. NLM UID: 7513587. 
KW  - Alcoholism -- Drug Therapy
KW  - Anxiety -- Chemically Induced
KW  - Depression -- Chemically Induced
KW  - Ethanol -- Adverse Effects
KW  - Receptors, Cell Surface -- Antagonists and Inhibitors
KW  - Substance Withdrawal Syndrome -- Drug Therapy
KW  - Clinical Trials
KW  - Drug Discovery
KW  - Models, Biological
KW  - Receptors, Cell Surface
KW  - Receptors, Cell Surface -- Metabolism
SP  - 175
EP  - 186 12p
JO  - Drug & Alcohol Dependence
JF  - Drug & Alcohol Dependence
JA  - DRUG ALCOHOL DEPENDENCE
VL  - 128
IS  - 3
PB  - Elsevier Science
AB  - BACKGROUND: Alcohol use disorders are chronic disabling conditions for which existing pharmacotherapies have only modest efficacy. In the present review, derived from the 2012 Behavior, Biology and Chemistry 'Translational Research in Addiction' symposium, we summarize the anti-relapse potential of corticotropin-releasing factor type 1 (CRF(1)) receptor antagonists to reduce negative emotional symptoms of acute and protracted alcohol withdrawal and stress-induced relapse to alcohol seeking. METHODS: We review the biology of CRF(1) systems, the activity of CRF(1) receptor antagonists in animal models of anxiolytic and antidepressant activity, and experimental findings in alcohol addiction models. We also update the clinical trial status of CRF(1) receptor antagonists, including pexacerfont (BMS-562086), emicerfont (GW876008), verucerfont (GSK561679), CP316311, SSR125543A, R121919/NBI30775, R317573/19567470/CRA5626, and ONO-2333Ms. Finally, we discuss the potential heterogeneity and pharmacogenomics of CRF(1) receptor pharmacotherapy for alcohol dependence. RESULTS: The evidence suggests that brain penetrant-CRF(1) receptor antagonists have therapeutic potential for alcohol dependence. Lead compounds with clinically desirable pharmacokinetic properties now exist, and longer receptor residence rates (i.e., slow dissociation) may predict greater CRF(1) receptor antagonist efficacy. Functional variants in genes that encode CRF system molecules, including polymorphisms in Crhr1 (rs110402, rs1876831, rs242938) and Crhbp genes (rs10055255, rs3811939) may promote alcohol seeking and consumption by altering basal or stress-induced CRF system activation. CONCLUSIONS: Ongoing clinical trials with pexacerfont and verucerfont in moderately to highly severe dependent anxious alcoholics may yield insight as to the role of CRF(1) receptor antagonists in a personalized medicine approach to treat drug or alcohol dependence.
SN  - 0376-8716
AD  - Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: ezorrilla@scripps.edu.
U2  - PMID: 23294766.
DO  - 10.1016/j.drugalcdep.2012.12.017
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104317269&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106511008
T1  - Bipolar disorder in school-age children.
AU  - Olson PM
AU  - Pacheco MR
Y1  - 2005/06//
N1  - Accession Number: 106511008. Language: English. Entry Date: 20050909. Revision Date: 20150820. Publication Type: Journal Article; review; tables/charts. Journal Subset: Nursing; Peer Reviewed; USA. NLM UID: 9206498. 
KW  - Bipolar Disorder -- In Infancy and Childhood
KW  - Bipolar Disorder -- Nursing -- In Infancy and Childhood
KW  - Child Psychology
KW  - School Health Nursing
KW  - Adolescence
KW  - Adult
KW  - Anticonvulsants -- Therapeutic Use
KW  - Antipsychotic Agents -- Therapeutic Use
KW  - Attention Deficit Hyperactivity Disorder
KW  - Bipolar Disorder -- Diagnosis
KW  - Bipolar Disorder -- Drug Therapy
KW  - Bipolar Disorder -- Epidemiology -- United States
KW  - Bipolar Disorder -- Etiology
KW  - Bipolar Disorder -- Physiopathology
KW  - Bipolar Disorder -- Symptoms
KW  - Brain -- Physiopathology
KW  - Child
KW  - Clinical Assessment Tools
KW  - Diagnosis, Differential
KW  - Lithium -- Adverse Effects
KW  - Lithium -- Therapeutic Use
KW  - Lorazepam -- Therapeutic Use
KW  - Neurotransmitters
KW  - Nursing Assessment
KW  - Psychotherapy
KW  - School Health Services
KW  - United States
SP  - 152
EP  - 157 6p
JO  - Journal of School Nursing (Allen Press Publishing Services Inc.)
JF  - Journal of School Nursing (Allen Press Publishing Services Inc.)
JA  - J SCH NURS (ALLEN PRESS)
VL  - 21
IS  - 3
CY  - Lawrence, Kansas
PB  - Allen Press Publishing Services Inc.
AB  - This article examines the individual components of bipolar disorder in children and the behaviors that can escalate as a result of misdiagnosis and treatment. The brain/behavior relationship in bipolar disorders can be affected by genetics, developmental failure, or environmental influences, which can cause an onset of dramatic mood swings and dysfunctional behavior. School is often the site where mental health disorders are observed when comparing behaviors with other children. Assessing the emotional, academic, and health needs of a student with a bipolar disorder is a critical step in designing effective interventions and school accommodations. Without appropriate medical, psychological, pharmaceutical, and academic interventions, a child is at risk for uncontrolled mania, depression, substance abuse, or suicide. The school nurse is part of the multidisciplinary team and plays a key role in facilitating case management to potentially reverse this possible negative trajectory. Successful case management provides children with bipolar disorder the opportunity to reach their academic potential.
SN  - 1059-8405
AD  - Area Nurse Consultant, Jefferson County School District, Arvada, CO
U2  - PMID: 15898850.
DO  - 10.1177/10598405050210030501
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106511008&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105468952
T1  - Brief intervention for anxiety in primary care patients.
AU  - Roy-Byrne P
AU  - Veitengruber JP
AU  - Bystritsky A
AU  - Edlund MJ
AU  - Sullivan G
AU  - Craske MG
AU  - Welch SS
AU  - Rose R
AU  - Stein MB
Y1  - 2009/03//2009 Mar-Apr
N1  - Accession Number: 105468952. Language: English. Entry Date: 20091002. Revision Date: 20150711. Publication Type: Journal Article; review; tables/charts. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Evidence-Based Practice; Psychiatry/Psychology. NLM UID: 101256526. 
KW  - Anxiety -- Therapy
KW  - Primary Health Care
KW  - Psychotherapy -- Methods
KW  - Antianxiety Agents -- Therapeutic Use
KW  - Anxiety -- Complications
KW  - Anxiety -- Diagnosis
KW  - Anxiety -- Drug Therapy
KW  - Anxiety -- Epidemiology
KW  - Anxiety -- Physiopathology
KW  - Behavior Modification
KW  - Cognitive Therapy
KW  - Decision Making, Clinical
KW  - Diazepam -- Therapeutic Use
KW  - Drug Resistance
KW  - Drug Therapy, Combination
KW  - Medical Practice, Evidence-Based
KW  - Psychotherapy -- Education
KW  - Quality of Health Care
KW  - Serotonin Uptake Inhibitors -- Therapeutic Use
SP  - 175
EP  - 186 12p
JO  - Journal of the American Board of Family Medicine
JF  - Journal of the American Board of Family Medicine
JA  - J AM BOARD FAM MED
VL  - 22
IS  - 2
CY  - Lexington, Kentucky
PB  - American Board of Family Medicine
AB  - To address the difficulty of assessing and managing multiple anxiety disorders in the primary care setting, this article provides a simple, easy-to-learn, unified approach to the diagnosis, care management, and pharmacotherapy of the 4 most common anxiety disorders found in primary care: panic, generalized anxiety disorders, social anxiety disorders, and posttraumatic stress disorder. This evidence-based approach was developed for an ongoing National Institute of Mental Health-funded study designed to improve the delivery of evidence-based medication and psychotherapy treatment to primary care patients with these anxiety disorders. We present a simple, validated method to screen for the 4 major disorders that emphasizes identifying other medical or psychiatric comorbidities that can complicate treatment; an approach for initial education of the patient and discussion about treatment, including provision of some simple cognitive behavioral therapy skills, based on motivational interviewing/brief intervention approaches previously used for substance use disorders; a validated method for monitoring treatment outcome; and an algorithmic approach for the selection of initial medication treatment, the selection of alternative or adjunctive treatments when the initial approach has not produced optimal results, and indications for mental health referral.
SN  - 1557-2625
AD  - Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Harborview Center for Healthcare Improvement for Addictions, Mental Illness and Medically Vulnerable Populations, Seattle.
U2  - PMID: 19264941.
DO  - 10.3122/jabfm.2009.02.080078
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105468952&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104169433
T1  - Buprenorphine for Chronic Pain.
AU  - Calderon, Raul
AU  - Copenhaver, David
Y1  - 2013/12//
N1  - Accession Number: 104169433. Language: English. Entry Date: 20131209. Revision Date: 20150711. Publication Type: Journal Article; questions and answers. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Pain and Pain Management; Palliative Care/Hospice. NLM UID: 101125608. 
KW  - Chronic Pain -- Drug Therapy
KW  - Buprenorphine -- Administration and Dosage
KW  - Transdermal Patches, Drugs
KW  - Morphine
KW  - Buprenorphine -- Pharmacokinetics
KW  - Buprenorphine -- Metabolism
KW  - Respiration Disorders -- Risk Factors
KW  - Drug Tolerance
KW  - Hyperalgesia
KW  - Dosage Calculation
KW  - Substance Withdrawal Syndrome -- Prevention and Control
SP  - 402
EP  - 405 4p
JO  - Journal of Pain & Palliative Care Pharmacotherapy
JF  - Journal of Pain & Palliative Care Pharmacotherapy
JA  - J PAIN PALLIAT CARE PHARMACOTHER
VL  - 27
IS  - 4
PB  - Taylor & Francis Ltd
AB  - Questions from patients about pain conditions, analgesic pharmacotherapy and responses from authors are presented to help educate patients and make them more effective self-advocates. The use of transdermal buprenorphine for chronic pain management is discussed. A brief history of the medication is provided. The use of the medication in opioid maintenance, and withdrawal and other concerns are discussed. Possible side effects are described.
SN  - 1536-0288
U2  - PMID: 24245573.
DO  - 10.3109/15360288.2013.847522
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104169433&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104487580
T1  - Canadian Pharmacists Association Conference, Whistler, BC.
Y1  - 2012/07//
N1  - Accession Number: 104487580. Language: English. Entry Date: 20120806. Revision Date: 20150711. Publication Type: Journal Article; abstract; pictorial; proceedings; tables/charts. Journal Subset: Biomedical; Canada; Peer Reviewed. NLM UID: 101257110. 
KW  - Pharmacists -- Canada
KW  - Congresses and Conferences -- Canada
KW  - Canada
KW  - Diabetes Mellitus, Type 2
KW  - Blood Glucose Self-Monitoring
KW  - Physician Attitudes -- Canada
KW  - Patient Safety
KW  - Pharmacy, Retail -- Canada
KW  - Medication Compliance
KW  - Health Screening
KW  - Pneumococcal Vaccine
KW  - Family Planning
KW  - Body Weights and Measures -- Scotland
KW  - Prescriptive Authority
KW  - Heart Failure
KW  - Patient Education
KW  - Cardiovascular Diseases -- Prevention and Control
KW  - Primary Health Care -- Canada
KW  - Glycemic Control
KW  - Posters
KW  - Pharmacists -- Education -- Canada
KW  - Student Attitudes
KW  - Immunization -- Quebec
KW  - Quebec
KW  - Influenza Vaccine -- Alberta
KW  - Alberta
KW  - Chronic Pain
KW  - Narcotics
KW  - Osteoarthritis -- Drug Therapy
KW  - Certification
KW  - Personality
KW  - Research, Medical
KW  - Professional Development
KW  - Kidney Diseases
KW  - Diabetes Mellitus
KW  - Professional Practice
KW  - Listserv
KW  - Computerized Literature Searching
KW  - Quality Assurance
KW  - Quality Improvement
KW  - Adverse Drug Event
KW  - Drug Therapy -- In Old Age
KW  - Aged
KW  - Aged, 80 and Over
KW  - Pediatrics
KW  - Chemotherapy, Cancer
KW  - Diabetes Mellitus -- Drug Therapy
KW  - Asthma -- Drug Therapy
KW  - Pulmonary Disease, Chronic Obstructive -- Drug Therapy
KW  - Cardiovascular Risk Factors
KW  - Hypertension -- Diagnosis
KW  - Blood Pressure -- Evaluation
KW  - Medicine, Chinese Traditional
KW  - Alternative Therapies
KW  - Patient Compliance
KW  - Professional Role
KW  - Scotland
KW  - Drug Therapy -- In Pregnancy
KW  - Pregnancy
KW  - Female
KW  - Pharmacy Technicians -- Canada
KW  - Health Knowledge
KW  - Substance Abuse, Intravenous
KW  - Harm Reduction
KW  - Mandatory Reporting
SP  - S1
EP  - S53 1p
JO  - Canadian Pharmacists Journal (Allen Press Publishing Services Inc.)
JF  - Canadian Pharmacists Journal (Allen Press Publishing Services Inc.)
JA  - CAN PHARM J
VL  - 145
IS  - 4
CY  - Lawrence, Kansas
PB  - Allen Press Publishing Services Inc.
SN  - 1715-1635
DO  - 10.3821/145.4.cpjS1
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104487580&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106437709
T1  - Characteristics of medication errors made by students during the administration phase: a descriptive study.
AU  - Wolf ZR
AU  - Hicks R
AU  - Serembus JF
Y1  - 2006/01//
N1  - Accession Number: 106437709. Language: English. Entry Date: 20060512. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 8511298. 
KW  - Medication Errors
KW  - Students, Nursing
KW  - Convenience Sample
KW  - Databases
KW  - Descriptive Research
KW  - Descriptive Statistics
KW  - Drug Administration -- Education
KW  - Drugs, Prescription -- Classification
KW  - Incident Reports
KW  - Medication Errors -- Classification
KW  - Medication Errors -- Etiology
KW  - Retrospective Design
KW  - Secondary Analysis
KW  - Voluntary Reporting
KW  - Human
SP  - 39
EP  - 51 13p
JO  - Journal of Professional Nursing
JF  - Journal of Professional Nursing
JA  - J PROF NURS
VL  - 22
IS  - 1
CY  - Philadelphia, Pennsylvania
PB  - W B Saunders
AB  - Faculty concentrate on teaching nursing students about safe medication administration practices and on challenging them to develop skills for calculating drug dose and intravenous flow rate problems. In spite of these efforts, students make medication errors and little is known about the attributes of these errors. Therefore, this descriptive, retrospective, secondary analysis study examined the characteristics of medication errors made by nursing students during the administration phase of the medication use process as reported to the MEDMARX, a database operated by the United States Pharmacopeia through the Patient Safety Program. Fewer than 3% of 1,305 student-made medication errors occurring in the administration process resulted in patient harm. Most were omission errors, followed by errors of giving the wrong dose (amount) of a drug. The most prevalent cause of the errors was students' performance deficits, whereas inexperience and distractions were leading contributing factors. The antimicrobial therapeutic class of drugs and the 10 subcategories within this class were the most commonly reported medications involved. Insulin was the highest-frequency single medication reported. Overall, this study shows that students' administration errors may be more frequent than suspected. Faculty might consider curriculum revisions that incorporate medication use safety throughout each course in nursing major courses. Copyright © 2006 by Elsevier Science (USA).
SN  - 8755-7223
AD  - Dean/Professor, La Salle University School of Nursing, 1900 West Olney Ave., Philadelphia, PA 19141
U2  - PMID: 16459288.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106437709&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106056514
T1  - Clinical Efficacy of Bupropion in the Management of Smoking Cessation.
AU  - Jorenby D
Y1  - 2002/07/02/2002 Supplement 2
N1  - Accession Number: 106056514. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article. Supplement Title: 2002 Supplement 2. Journal Subset: Australia & New Zealand; Biomedical; Peer Reviewed. NLM UID: 7600076. 
SP  - 25
EP  - 35 11p
JO  - Drugs
JF  - Drugs
JA  - DRUGS
VL  - 62
IS  - 11
PB  - Springer Science & Business Media B.V.
AB  - Nicotine addiction is a chronic relapsing condition that can be difficult to treat. Until recently, pharmacological options for the treatment of tobacco dependence were primarily limited to nicotine replacement therapy (NRT). Sustained-release bupropion (bupropion SR) is the first non-nicotine pharmacological treatment approved for smoking cessation. Bupropion SR is recommended for first-line pharmacotherapy alongside NRT in the updated US Clinical Practice Guidelines and the UK Health Education Authority Guidelines. The UK National Institute of Clinical Excellence recommends NRT and bupropion SR for smokers who have expressed a desire to quit smoking. This review presents evidence that bupropion SR is an effective first-line therapy for smoking cessation in a wide range of patient populations. It is associated with significantly higher smoking cessation rates compared with placebo in patients with or without a history of prior bupropion SR or NRT use, and its effect is independent of gender. Bupropion SR treatment is effective in the prevention of relapse to smoking in those patients who have successfully quit, and re-treatment is effective in smokers who recommence smoking after a previous course of bupropion SR. Bupropion SR treatment relieves the symptoms of craving and nicotine withdrawal, and attenuates the weight gain that often occurs after smoking cessation. Data collected from motivational support programmes and employer-based studies provide strong evidence of the effectiveness of bupropion SR as an aid to smoking cessation in 'real life' situations, and confirm the efficacy seen in clinical trials.
SN  - 0012-6667
U2  - PMID: 12109933.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107137145
T1  - Cocaine misuse treatment in England.
AU  - Seivewright N
AU  - Donmall M
AU  - Douglas J
AU  - Draycott T
AU  - Millar T
Y1  - 2000/06//2000 Jun 1
N1  - Accession Number: 107137145. Language: English. Entry Date: 20001001. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Instrumentation: Opiate Treatment Index (Darke et al). NLM UID: 9014759. 
KW  - Substance Abuse -- Epidemiology -- England
KW  - Cocaine
KW  - Substance Abuse -- Therapy -- England
KW  - England
KW  - Surveys
KW  - Outcome Assessment
KW  - Questionnaires
KW  - Telephone
KW  - Semi-Structured Interview
KW  - Prospective Studies
KW  - Research Instruments
KW  - Research Subject Recruitment
KW  - Descriptive Statistics
KW  - Counseling
KW  - Combined Modality Therapy
KW  - Substance Abuse -- Drug Therapy -- England
KW  - Male
KW  - Female
KW  - Adult
KW  - Whites
KW  - Blacks
KW  - P-Value
KW  - Wilcoxon Rank Sum Test
KW  - Two-Tailed Test
KW  - Human
SP  - 203
EP  - 215 13p
JO  - International Journal of Drug Policy
JF  - International Journal of Drug Policy
JA  - INT J DRUG POLICY
VL  - 11
IS  - 3
CY  - New York, New York
PB  - Elsevier Science
AB  - Three methods were used to identify the treatments given to cocaine misusers in England, and to make a preliminary assessment of effectiveness. First, a postal survey of all known drug misuse treatment services ascertained approximate numbers of cocaine misusers presenting and receiving a specified range of treatments. Secondly, staff at selected services were interviewed regarding treatment policies, and asked to subjectively rate short-term and long-term effectiveness. Thirdly, a cohort of individuals in treatment were studied prospectively to assess changes in drug usage and associated problems. Fifty percent of services responded to the survey, but there was known to be significant duplication in service listings and it is considered that a representative pattern of clinical activity has been detected. Approximately half those services had recently treated cocaine misusers, mainly using counselling, residential rehabilitation, and pharmacological treatments, in which 32 different medications were identified. Acupuncture was prominent in a minority of services. Staff interviews suggested several principles in managing cocaine misusers, while all treatments were rated as being more effective in short-term relief of withdrawal features than in enabling longer-term abstinence. The treatment cohort were mostly in residential rehabilitation, and marked reductions in drug use and related clinical and social problems were demonstrated. © 2000 Elsevier Science B.V. All rights reserved.
SN  - 0955-3959
AD  - Substance Misuse Service, Community Health Sheffield NHS Trust, Norfolk House, 4 Norfolk St., Sheffield S1 2JB, UK
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106611488
T1  - Cocaine Rapid Efficacy Screening Trial (CREST): a paradigm for the controlled evaluation of candidate medications for cocaine dependence.
AU  - Leiderman DB
AU  - Shoptaw S
AU  - Montgomery A
AU  - Bloch DA
AU  - Elkashef A
AU  - LoCastro J
AU  - Vocci F
Y1  - 2005/03/02/Mar2005 Supplement 1
N1  - Accession Number: 106611488. Language: English. Entry Date: 20050422. Revision Date: 20150711. Publication Type: Journal Article; clinical trial; research; tables/charts. Supplement Title: Mar2005 Supplement 1. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Instrumentation: Addiction Severity Index (ASI) (McLellan et al); Hamilton Rating Scale for Depression (HRSD); Brief Substance Craving Scale (BSCS); Clinical Global Impression Scores (Tracy et al); Structured Clinical Inventory for the DSM-IV (SCID) (Spitzer et al); Hamilton Anxiety Rating Scale; Risk Assessment Battery (RAB) (Navaline et al). Grant Information: Funded by the National Institute on Drug Abuse (NIDA) through Interagency Agreement Y01 DA 50038-05. NLM UID: 9304118. 
KW  - Cocaine
KW  - Substance Dependence -- Drug Therapy
KW  - Clinical Trials
KW  - Counseling
KW  - Female
KW  - Fisher's Exact Test
KW  - Funding Source
KW  - Hamilton Rating Scale for Depression
KW  - Interview Guides
KW  - Male
KW  - Mann-Whitney U Test
KW  - Outpatients
KW  - Post Hoc Analysis
KW  - Random Assignment
KW  - Research Instruments
KW  - Reserpine -- Therapeutic Use
KW  - Scales
KW  - Self Report
KW  - Summated Rating Scaling
KW  - T-Tests
KW  - Treatment Outcomes
KW  - Two-Tailed Test
KW  - Type I Error
KW  - United States
KW  - Human
SP  - 1
EP  - 11 11p
JO  - Addiction
JF  - Addiction
JA  - ADDICTION
VL  - 100
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Aim Development of effective medications for the treatment of cocaine dependence remains a major priority for the National Institute on Drug Abuse (NIDA) at the National Institutes of Health. The Cocaine Rapid Efficacy Screening Trial (CREST) paradigm was developed by the Division of Treatment Research and Development (DT R&D) at NIDA with the goal of enhancing pilot clinical trial validity when systematically assessing a range of medications and drug classes for potential utility in treatment of cocaine dependence.Design CREST utilizes a randomized, controlled, parallel group, blinded methodology for comparing one or more marketed medications against a standard, pharmaceutical grade placebo. The trial design is comprised of a flexible 2 4-week screening/baseline period followed by randomization to an 8-week treatment period.Measures Standard measures of outcomes for the CREST included urinary benzoylecgonine (primary metabolite of cocaine), retention, cocaine craving, depression, clinical global impression and HIV-risk behaviors. In order to facilitate comparisons of data from the CREST studies across sites, drug classes and time, standardized procedures, measures and psychosocial counseling were used.Results A total of 19 medications were evaluated in out-patient treatment research clinics in Boston, Cincinnati, Los Angeles, New York and Philadelphia.Conclusions Findings supported decisions to move forward three medications (cabergoline, reserpine, tiagabine) using full-scale, adequately powered, randomized placebo-controlled trial designs. Lessons learned from the CREST experience continue to shape cocaine pharmacotherapy trial design and execution.
SN  - 0965-2140
AD  - Director, Food Substance Staff, Center for Drug Evaluation and Research, Food and Drug Administration, Rockville, MD 20852; leidermand@cder.fda.gov
U2  - PMID: 15773068.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105381912
T1  - College student receptiveness to various alcohol treatment options.
AU  - Epler AJ
AU  - Sher KJ
AU  - Loomis TB
AU  - O'Malley SS
Y1  - 2009/07//Jul/Aug2009
N1  - Accession Number: 105381912. Language: English. Entry Date: 20090821. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 7503059. 
KW  - Alcohol Rehabilitation Programs -- Methods
KW  - Attitude to Health
KW  - Students, College
KW  - Adult
KW  - Computer Assisted Instruction
KW  - Correlational Studies
KW  - Counseling
KW  - Descriptive Statistics
KW  - DSM
KW  - Female
KW  - Health Education
KW  - Male
KW  - Naltrexone -- Administration and Dosage
KW  - Prospective Studies
KW  - Psychotherapy, Group
KW  - Scales
KW  - Self Directed Learning
KW  - Support Groups
KW  - Human
SP  - 26
EP  - 32 7p
JO  - Journal of American College Health
JF  - Journal of American College Health
JA  - J AM COLL HEALTH
VL  - 58
IS  - 1
PB  - Taylor & Francis Ltd
AB  - Objective: Heavy episodic drinking remains a significant problem on college campuses. Although most interventions for college students are behavioral, pharmacological treatments, such as naltrexone, could provide additional options. Participants: The authors evaluated receptivity to various alcohol treatment options in a general population of college student drinkers (N = 2,084), assessed in 2005. Methods: The authors asked participants to indicate which of 8 treatment options (ie, self-help book, self-help computer program, self-help group, group therapy, individual therapy, monthly injection, targeted oral medication, or daily oral medication) they would be willing to consider if they were going to cut down on or stop drinking. Results: Over 50% of drinkers expressed receptiveness to self-help options or psychotherapy options, and over 25% of drinkers expressed receptiveness to medication options. Conclusions: Increasing treatment options for students interested in reducing or stopping drinking by offering pharmacological interventions such as naltrexone could provide an important unmet need among college students.
SN  - 0744-8481
AD  - Department of Psychological Sciences, University of Missouri, Midwest Alcoholism Research Center, Columbia, MO.
U2  - PMID: 19592350.
DO  - 10.3200/JACH.58.1.26-32
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105687771
T1  - Combining exposure and pharmacotherapy in the treatment of social anxiety disorder: a preliminary study of state dependent learning.
AU  - Morissette S
AU  - Spiegel D
AU  - Barlow D
Y1  - 2008/09//
N1  - Accession Number: 105687771. Language: English. Entry Date: 20081114. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; USA. Special Interest: Psychiatry/Psychology. Instrumentation: Subjective Units of Distress Scale (SUDS); Anxiety Disorders Interview Schedule-IV: Lifetime Version (ADIS-IV-L) (DiNardo et al); Positive and Negative Affect Schedule (PANAS)(Watson et al). NLM UID: 8608482. 
KW  - Antianxiety Agents, Benzodiazepine -- Therapeutic Use
KW  - Learning
KW  - Social Anxiety Disorders -- Drug Therapy
KW  - Substance Dependence -- Therapy
KW  - Social Anxiety Disorders
KW  - Adult
KW  - Antianxiety Agents, Benzodiazepine -- Administration and Dosage
KW  - Behavior Therapy
KW  - Coefficient Alpha
KW  - Combined Modality Therapy
KW  - Comparative Studies
KW  - Experimental Studies
KW  - Female
KW  - Internal Consistency
KW  - Interviews
KW  - Male
KW  - Massachusetts
KW  - Questionnaires
KW  - Random Assignment
KW  - Sample Size
KW  - Scales
KW  - Self Report
KW  - Test-Retest Reliability
KW  - Treatment Outcomes
KW  - Videorecording
KW  - Human
SP  - 211
EP  - 219 9p
JO  - Journal of Psychopathology & Behavioral Assessment
JF  - Journal of Psychopathology & Behavioral Assessment
JA  - J PSYCHOPATHOL BEHAV ASSESS
VL  - 30
IS  - 3
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
SN  - 0882-2689
AD  - Center for Anxiety and Related Disorders, Boston University, Boston, MA
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107420161
T1  - Commentary on Nursing knowledge: acute postoperative pain management in the elderly [original article by Brockopp DY et al appears in J GERONTOL NURS 1993;19(11):31-7].
AU  - Tanabe P
Y1  - 1994/05//1994 May-Jun
N1  - Accession Number: 107420161. Language: English. Entry Date: 19950901. Revision Date: 20150711. Publication Type: Journal Article; abstract; brief item; commentary. Journal Subset: Nursing; Peer Reviewed; USA. NLM UID: 9207215. 
KW  - Postoperative Pain -- Drug Therapy -- In Old Age
KW  - Nursing Knowledge -- Evaluation
KW  - Students, Nursing
KW  - Medical-Surgical Nursing
KW  - Questionnaires
KW  - Content Validity
KW  - Comparative Studies
KW  - Adult
KW  - Middle Age
KW  - Aged
KW  - Aged, 80 and Over
SP  - 21
EP  - 21 1p
JO  - ENA'S Nursing Scan in Emergency Care
JF  - ENA'S Nursing Scan in Emergency Care
JA  - ENAS NURS SCAN EMERG CARE
VL  - 4
IS  - 3
CY  - Philadephia, Pennsylvania
PB  - Nursecom Inc.
AB  - The literature has demonstrated extensively the problem of inadequate pain management, but there has been insufficient research among the elderly population. The authors developed and administered the Acute Postoperative Pain Inventory: Elderly Patients to investigate the baseline pain-management knowledge of 65 staff nurses, RNs with 2 or more years of acute care experience, and 70 student nurses. The tool measures basic pharmacologic concepts, potential for addiction, and the goals of pain medication as applied to the elderly population. Staff nurses scored significantly higher than student nurses. However, both groups scored very low on the questionnaire indicating a significant (p<O.OOl) deficit in nursing knowledge of pain-management concepts in the elderly. [Original article accession number: 1994176559 (research, tables/charts)]
SN  - 1056-7062
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106366573
T1  - Community outreach with weekly delivery of anti-retroviral drugs compared to cognitive-behavioural health care team-based approach to improve adherence among indigent women newly starting HAART.
AU  - Visnegarwala F
AU  - Rodriguez-Barradass MC
AU  - Graviss EA
AU  - Caprio M
AU  - Nykyforchyn M
AU  - Laufman L
Y1  - 2006/05//
N1  - Accession Number: 106366573. Language: English. Entry Date: 20061124. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology. Instrumentation: Interpersonal Support Evaluation List (ISEL); Hamilton Rating Scale for Depression (HRSD); Zung Depression Scale; Short Form 12 Health Survey (SF-12). Grant Information: Grant, Center for AIDS Research at Baylor College of Medicine: NIH Grant # AI36211; grant, Bristol Myers Squibb Foundation. NLM UID: 8915313. 
KW  - Antiretroviral Therapy, Highly Active
KW  - Cognitive Therapy -- Methods
KW  - HIV Infections -- Therapy
KW  - Adult
KW  - Chi Square Test
KW  - Community Health Services
KW  - Comparative Studies
KW  - Confidence Intervals
KW  - Female
KW  - Fisher's Exact Test
KW  - Funding Source
KW  - Hamilton Rating Scale for Depression
KW  - Medication Compliance
KW  - Odds Ratio
KW  - P-Value
KW  - Pilot Studies
KW  - Prospective Studies
KW  - Psychological Tests
KW  - Scales
KW  - Self Report
KW  - T-Tests
KW  - Texas
KW  - Treatment Outcomes
KW  - Human
SP  - 332
EP  - 338 7p
JO  - AIDS Care
JF  - AIDS Care
JA  - AIDS CARE
VL  - 18
IS  - 4
CY  - Oxfordshire, <Blank>
PB  - Routledge
AB  - Sustained virological suppression requires adherence to >95% of doses of therapy. Overall there is paucity of data on adherence interventions among women and post-intervention outcomes. In this pilot study, we evaluated a novel strategy of weekly delivery of medications (Directly Delivered Therapy: DDT) for six months using an outreach worker (ORW), among ARV naïve indigent women starting HAART and compared the 'during intervention' and 'post-intervention' outcomes to the health care team (a nurse educator, a case worker, a pharmacist and social worker/drug addictions counsellor) based approach termed Adherence Coordination Services (ACS) and the Standard of Care (SoC) historical referent group. The baseline characteristics of the three groups were comparable. The proportion of women who achieved sustained virologic suppression in 4-8 month period for DDT; ACS and SoC groups were 86% (18/21); 54% (6/11); and 36% (8/22) ( P < 0.004); and in the 10-14 month period were 80% (12/15); 54% (6/11) and 45%(10/22) (P=0.036 for DDT vs. SoC). Retention rate in the DDT was 87%, and 92% of 307 ORW visits were kept, and post-intervention satisfaction was high. Short-term weekly delivery of medications using a community based liaison is a feasible, acceptable and a cost-effective strategy for improving both short-term and perhaps long-term adherence among women initiating their first HAART regimen.
SN  - 0954-0121
AD  - Baylor College of Medicine, Department of Medicine, Section of Infectious Diseases, One Baylor Plaza, Room # 465 EC, Houston, TX 77030; fehmidav@bcm.tmc.edu
U2  - PMID: 16809110.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106366573&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106082231
T1  - Community pharmacist perspectives on HIV/AIDS and interventions for injection drug users in Canada.
AU  - Myers T
AU  - Cockerill R
AU  - Worthington C
AU  - Millson M
AU  - Rankin J
Y1  - 1998/12//
N1  - Accession Number: 106082231. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 8915313. 
KW  - Attitude to Health
KW  - HIV Infections -- Prevention and Control
KW  - Pharmacy, Retail
KW  - Substance Abuse, Intravenous -- Rehabilitation
KW  - Canada
KW  - Female
KW  - Health Care Delivery
KW  - HIV Infections -- Psychosocial Factors
KW  - Male
KW  - Needle Exchange Programs
KW  - Substance Abuse, Intravenous -- Psychosocial Factors
KW  - Syringes -- Supply and Distribution
SP  - 689
EP  - 700 12p
JO  - AIDS Care
JF  - AIDS Care
JA  - AIDS CARE
VL  - 10
IS  - 6
CY  - Oxfordshire, <Blank>
PB  - Routledge
AB  - In several countries, community pharmacies play a major role in the provision of HIV prevention services to injection drug users (IDUs). In this study, results from a national Canadian Survey of Community Pharmacies and HIV/AIDS Prevention are used to describe pharmacists' perspectives on HIV/AIDS and services to IDUs, and explore the relationship between personal and organizational characteristics and the level of support for HIV/AIDS prevention initiatives. A mailed questionnaire was directed to a random sample of 2,017 pharmacist owner-managers. The response rate was 84.6%. Results suggest that current services to IDUs primarily are limited to discretionary needle and syringe sales to non-diabetics, with almost three-quarters supportive. Staff safety was an important consideration in the provision of this service (77%), while remuneration was the lowest (27%). Community pharmacists were most comfortable with the provision of counselling, advice and literature (X = 2.6) and environmental and technological interventions (X = 2.4) and least supportive of provision of services as part of a programme (X = 1.6) and legalization of drugs or prescription of methodone (X = 1.9). Female pharmacists were more likely to support preventive measures such as the provision of counselling or advice, and males were more likely to promote legislative change. Pharmacists appear generally willing to expand their services in the fight against HIV/AIDS. However, it is not feasible to expect uniform programmes to be immediately introduced. While organizational, educational and policy changes may facilitate programme development, individual pharmacy and pharmacist discretion remains important.
SN  - 0954-0121
U2  - PMID: 9924524.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104726447
T1  - Community pharmacists' experience of over-the-counter medicine misuse in Scotland.
AU  - MacFadyen, L
AU  - Eadie, D
AU  - McGowan, T
Y1  - 2001/09//2001 Sep
N1  - Accession Number: 104726447. Language: English. Entry Date: 20110610. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Europe; Health Promotion/Education; Peer Reviewed; Public Health; UK & Ireland. NLM UID: 101499616. 
KW  - Ethics, Professional
KW  - Drugs, Non-Prescription -- Standards
KW  - Pharmacists
KW  - Self Medication -- Standards
KW  - Substance Use Disorders
KW  - Evaluation Research
KW  - Human
KW  - Drugs, Non-Prescription -- Adverse Effects
KW  - Professional Role
KW  - Public Health
KW  - Scotland
KW  - Self Medication -- Adverse Effects
SP  - 185
EP  - 192 8p
JO  - Journal of the Royal Society for the Promotion of Health
JF  - Journal of the Royal Society for the Promotion of Health
JA  - J R SOC PROMOT HEALTH
VL  - 121
IS  - 3
PB  - Sage Publications, Ltd.
AB  - Over the last decade Britain has observed a trend towards the re-regulation of 'prescription only medicines' in favour of pharmacy status drugs. This move towards self-treatment to reduce pressures on general practitioner drug budgets and workloads has focused attention on the need for community pharmacists to extend their patient education and screening roles. In response to these changes, this study was conducted to explore: the type of over-the-counter (OTC) medicine being misused in Scotland; pharmacists' professional attitudes and management of OTC misuse; and the training and support needs of pharmacists. A postal questionnaire was designed. This was informed by an earlier stage of qualitative research and the available literature. It was then piloted and administered to all 110 pharmacies in the study area. A 79% response rate was achieved. The research found that OTC misuse, particularly of certain analgesics, sleeping prescriptions, products containing codeine or pseudoephedrine, caffeine, cough mixtures, and laxatives was common. The estimated mean number of patients suspected of misusing medicines in a typical week was 5.63. Pharmacies in urban areas were more likely than those in rural areas to report suspected misuse. The research identified a number of intervention strategies relating to: patient/pharmacist interaction; information provision; removal of products from the point of sale; sharing of information with other local pharmacists; and referral to other members of the primary care team. Pharmacists expressed a need for support in managing OTC misuse and in organising 'early warning systems' to share information locally.
SN  - 1466-4240
AD  - Centre for Social Marketing, University of Strathclyde, 173 Cathedral Street, Glasgow G4 0RQ, Scotland. l.macfadyen@csm.market.strath.ac.uk
U2  - PMID: 11688306.
DO  - 10.1177/146642400112100316
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107166483
T1  - Community pharmacy in Wales: 1995 data on HIV prevention and drug misuse services.
AU  - Sheridan J
AU  - Strang J
Y1  - 1998/04//
N1  - Accession Number: 107166483. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Double Blind Peer Reviewed; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9212352. 
KW  - Pharmacy Service -- Wales
KW  - Pharmacy Service -- England
KW  - Needle Exchange Programs
KW  - HIV Infections -- Prevention and Control -- Wales
KW  - Substance Abuse -- Drug Therapy -- Wales
KW  - Wales
KW  - Questionnaires
KW  - Mail
KW  - Descriptive Statistics
KW  - Simple Random Sample
KW  - Data Analysis, Statistical
KW  - Comparative Studies
KW  - England
KW  - Sharps Disposal
KW  - Attitude of Health Personnel -- Evaluation
KW  - Education, Pharmacy
KW  - Human
SP  - 203
EP  - 210 8p
JO  - Journal of Mental Health
JF  - Journal of Mental Health
JA  - J MENT HEALTH
VL  - 7
IS  - 2
CY  - Oxfordshire, <Blank>
PB  - Routledge
AB  - Using a postal questionnaire mailed to a random one in four sample of community pharmacies in Wales, information on service provision for drug misusers, attitude towards services, and participation in training was obtained. After four mailshots, the final response was 137/178 pharmacies (77%). Forty-one percent of respondents were dispensing controlled drugs for the treatment of addiction, 34% were selling injecting equipment, and 31% were operating a needle exchange scheme--all substantial increases since 1988. Four-fifths believed the community pharmacist had a role to play in HIV prevention and two-thirds indicated a need for service-specific training. Two-fifths of respondents were in favour of a role for community pharmacists supervising the consumption of methadone in the pharmacy. The results also indicate further scope for increasing participation in service provision and for an expanded role for the community pharmacist, with suitable training and support.
SN  - 0963-8237
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109803494
T1  - Comprehensive Review of Medicinal Marijuana, Cannabinoids, and Therapeutic Implications in Medicine and Headache: What a Long Strange Trip It's Been ...
AU  - Baron, Eric P.
Y1  - 2015/06//
N1  - Accession Number: 109803494. Language: English. Entry Date: 20150826. Revision Date: 20150923. Publication Type: Journal Article; review; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Pain and Pain Management. NLM UID: 2985091R. 
KW  - Medical Marijuana -- History
KW  - Phytochemicals -- Pharmacodynamics
KW  - Endocrine System -- Physiology
KW  - Headache -- Drug Therapy
KW  - Pain -- Drug Therapy
KW  - Phytochemicals -- Pharmacokinetics
KW  - Cannabis -- Adverse Effects
KW  - Central Nervous System -- Drug Effects
KW  - Cardiovascular System -- Drug Effects
KW  - Respiratory System -- Drug Effects
KW  - Gastrointestinal System -- Drug Effects
KW  - Immune System -- Drug Effects
KW  - Reproduction -- Drug Effects
KW  - Cannabis -- Contraindications
KW  - Phytochemicals -- Contraindications
SP  - 885
EP  - 916 32p
JO  - Headache: The Journal of Head & Face Pain
JF  - Headache: The Journal of Head & Face Pain
JA  - HEADACHE
VL  - 55
IS  - 6
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Background The use of cannabis, or marijuana, for medicinal purposes is deeply rooted though history, dating back to ancient times. It once held a prominent position in the history of medicine, recommended by many eminent physicians for numerous diseases, particularly headache and migraine. Through the decades, this plant has taken a fascinating journey from a legal and frequently prescribed status to illegal, driven by political and social factors rather than by science. However, with an abundance of growing support for its multitude of medicinal uses, the misguided stigma of cannabis is fading, and there has been a dramatic push for legalizing medicinal cannabis and research. Almost half of the United States has now legalized medicinal cannabis, several states have legalized recreational use, and others have legalized cannabidiol-only use, which is one of many therapeutic cannabinoids extracted from cannabis. Physicians need to be educated on the history, pharmacology, clinical indications, and proper clinical use of cannabis, as patients will inevitably inquire about it for many diseases, including chronic pain and headache disorders for which there is some intriguing supportive evidence. Objective To review the history of medicinal cannabis use, discuss the pharmacology and physiology of the endocannabinoid system and cannabis-derived cannabinoids, perform a comprehensive literature review of the clinical uses of medicinal cannabis and cannabinoids with a focus on migraine and other headache disorders, and outline general clinical practice guidelines. Conclusion The literature suggests that the medicinal use of cannabis may have a therapeutic role for a multitude of diseases, particularly chronic pain disorders including headache. Supporting literature suggests a role for medicinal cannabis and cannabinoids in several types of headache disorders including migraine and cluster headache, although it is primarily limited to case based, anecdotal, or laboratory-based scientific research. Cannabis contains an extensive number of pharmacological and biochemical compounds, of which only a minority are understood, so many potential therapeutic uses likely remain undiscovered. Cannabinoids appear to modulate and interact at many pathways inherent to migraine, triptan mechanisms ofaction, and opiate pathways, suggesting potential synergistic or similar benefits. Modulation of the endocannabinoid system through agonism or antagonism of its receptors, targeting its metabolic pathways, or combining cannabinoids with other analgesics for synergistic effects, may provide the foundation for many new classes of medications. Despite the limited evidence and research suggesting a role for cannabis and cannabinoids in some headache disorders, randomized clinical trials are lacking and necessary for confirmation and further evaluation.
SN  - 0017-8748
AD  - Department of Neurology, Headache Center, Cleveland Clinic Neurological Institute
U2  - PMID: 26015168.
DO  - 10.1111/head.12570
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104470002
T1  - Computerized physician order entry system combined with on-ward pharmacist: analysis of pharmacists' interventions.
AU  - Bedouch, Pierrick
AU  - Tessier, Alexandre
AU  - Baudrant, Magalie
AU  - Labarere, José
AU  - Foroni, Luc
AU  - Calop, Jean
AU  - Bosson, Jean-Luc
AU  - Allenet, Benoît
Y1  - 2012/08//
N1  - Accession Number: 104470002. Language: English. Entry Date: 20120801. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; Public Health; UK & Ireland. Special Interest: Public Health. NLM UID: 9609066. 
KW  - Adverse Drug Event -- Prevention and Control
KW  - Pharmacists
KW  - Electronic Order Entry
KW  - Pharmacy Service
KW  - Interprofessional Relations
KW  - Patient Safety -- Methods
KW  - Academic Medical Centers
KW  - France
KW  - Human
KW  - Prospective Studies
KW  - Multiple Regression
KW  - Logistic Regression
KW  - Descriptive Statistics
KW  - Guideline Adherence
KW  - Drug Interactions
KW  - Drug Monitoring
KW  - Drug Administration
KW  - Odds Ratio
KW  - Confidence Intervals
KW  - Physician Attitudes
KW  - Communication -- Methods
KW  - Interns and Residents
KW  - Outcome Assessment -- Methods
KW  - Quality Assessment -- Methods
KW  - Kappa Statistic
KW  - Chi Square Test
KW  - Fisher's Exact Test
KW  - Goodness of Fit Chi Square Test
KW  - Data Analysis Software
KW  - Male
KW  - Female
KW  - Aged
KW  - Adolescence
KW  - Adult
KW  - Aged, 80 and Over
KW  - Middle Age
KW  - Young Adult
SP  - 911
EP  - 918 8p
JO  - Journal of Evaluation in Clinical Practice
JF  - Journal of Evaluation in Clinical Practice
JA  - J EVAL CLIN PRACT
VL  - 18
IS  - 4
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Rationale, aims and objectives To analyse pharmacists' interventions in a setting where a computerized physician order entry system (CPOE) is in use and a pharmacist works on the ward. Method A prospective cohort study was conducted in seven wards of a French teaching hospital using CPOE along with the presence of a full-time on-ward pharmacy resident. We documented the characteristics of pharmacists' interventions communicated to physicians during the medication order validation process whenever a drug-related problem was identified. Independent predictors of the physician's acceptance of the pharmacist's intervention were assessed using multiple logistic regression analysis. Results The 448 pharmacists' interventions concerned: non-conformity to guidelines or contraindications (22%), too high doses (19%), drug interactions (15%) and improper administration (15%). The interventions consisted of changes in drug choice (41%), dose adjustment (23%), drug monitoring (19%) and optimization of administration (17%). Interventions were communicated via the CPOE in 57% of cases and 43% orally. The rate of physicians' acceptance was 79.2%. In multivariate analysis, acceptance was significantly associated with the physician's status [higher for residents vs. seniors: OR = 7.23, CI 95 (2.37-22.10), P < 0.01], method of communication [higher for oral vs. computer communication: OR = 12.5, CI 95 (4.16-37.57), P < 0.01] and type of recommendation [higher for drug monitoring vs. drug choice recommendations: OR = 10.32, CI 95 (3.20-33.29), P < 0.01]. Conclusions When a clinical pharmacist is present on a ward in which a CPOE is in use, the pharmacists' interventions are well accepted by physicians. Specific predictors of the acceptance by physicians emerge, but further research as to the impact of CPOE on pharmacist-physician communication is needed.
SN  - 1356-1294
AD  - Pharmacist, Pharmacy Department, Grenoble University Hospital, Grenoble, France and Associate Researcher, UJF-Grenoble 1/CNRS/TIMC-IMAG UMR 5525/Themas, Grenoble, France
AD  - Pharmacist, Pharmacy Department, Grenoble University Hospital, Grenoble, France
AD  - Associate Professor in Public Health Sciences, Quality of Care Unit, Grenoble University Hospital, Grenoble, France and UJF-Grenoble 1/CNRS/TIMC-IMAG UMR 5525/Themas, Grenoble, France
AD  - Professor in Clinical Pharmacy
AD  - Professor in Biostatistics and Medical Informatics, Clinical Research Centre, Grenoble University Hospital, Grenoble, France and UJF-Grenoble 1/CNRS/TIMC-IMAG UMR 5525/Themas, Grenoble, France
AD  - Associate Professor in Clinical Pharmacy, Pharmacy Department, Grenoble University Hospital, Grenoble, France and UJF-Grenoble 1/CNRS/TIMC-IMAG UMR 5525/Themas, Grenoble, France
U2  - PMID: 21689216.
DO  - 10.1111/j.1365-2753.2011.01704.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108249204
T1  - Considerations for the upcoming FDA REMS proposal.
AU  - Peppin JF
AU  - Coleman JJ
AU  - Kirsh KL
Y1  - 2011/05//2011 May-Jun
N1  - Accession Number: 108249204. Language: English. Entry Date: 20110902. Revision Date: 20150712. Publication Type: Journal Article; editorial. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 101234523. 
KW  - Analgesics, Opioid
KW  - Prescriptions, Drug -- Standards
KW  - Substance Use Disorders -- Epidemiology
KW  - Risk Assessment -- Legislation and Jurisprudence
KW  - Risk Assessment -- Standards
KW  - United States Food and Drug Administration
KW  - Delayed-Action Preparations
KW  - Witness, Legal
KW  - Substance Use Disorders -- Prevention and Control
KW  - Pain -- Drug Therapy
KW  - Palliative Care
KW  - Patient Education
KW  - Pharmacy and Pharmacology -- Education
KW  - Nomenclature
KW  - United States
SP  - 173
EP  - 176 4p
JO  - Journal of Opioid Management
JF  - Journal of Opioid Management
JA  - J OPIOID MANAGE
VL  - 7
IS  - 3
CY  - Weston, Massachusetts
PB  - Weston Medical Publishing, LLC
SN  - 1551-7489
U2  - PMID: 21823548.
DO  - 10.5055/jom.2011.0060
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105375328
T1  - Contemporary clinical opioid use: opportunities and challenges.
AU  - Lanier WL
AU  - Kharasch ED
Y1  - 2009/07//
N1  - Accession Number: 105375328. Language: English. Entry Date: 20090807. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 0405543. 
KW  - Analgesics, Opioid -- Administration and Dosage
KW  - Analgesics, Opioid -- Adverse Effects
KW  - Pain -- Drug Therapy
KW  - Pain -- Epidemiology
KW  - Pharmacy and Pharmacology -- Education
KW  - Substance Use Disorders -- Epidemiology
KW  - Attitude of Health Personnel
SP  - 572
EP  - 575 4p
JO  - Mayo Clinic Proceedings
JF  - Mayo Clinic Proceedings
JA  - MAYO CLIN PROC
VL  - 84
IS  - 7
CY  - Philadelphia, Pennsylvania
PB  - Elsevier Inc.
SN  - 0025-6196
AD  - Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA. lanier.william@mayo.edu
U2  - PMID: 19567709.
DO  - 10.4065/84.7.572
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104752341
T1  - Continuing education for general practice and the role of the pharmaceutical industry.
AU  - Hayes, T M
AU  - Allery, L A
AU  - Harding, K G
AU  - Owen, P A
Y1  - 1990/12//1990 Dec
N1  - Accession Number: 104752341. Language: English. Entry Date: 20110610. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Europe; UK & Ireland. NLM UID: 9005323. 
KW  - Industry
KW  - Education, Medical, Continuing
KW  - Family Practice -- Education
KW  - Drug Therapy
KW  - Female
KW  - Great Britain
KW  - Male
SP  - 510
EP  - 512 3p
JO  - British Journal of General Practice
JF  - British Journal of General Practice
JA  - BR J GEN PRACT
VL  - 40
IS  - 341
PB  - Royal College of General Practitioners
AB  - A survey of the involvement in and attitudes towards continuing medical education of 101 general practitioners achieved a 95% response rate. Ninety per cent of the 96 doctors worked in practices which held meetings the content of which was organized by representatives of pharmaceutical companies but only 46% worked in practices which organized their own educational meetings. Seventy six per cent attended meetings away from their practice which were organized by drug companies and 75% had attended at some time continuing medical education activities organized by a local postgraduate centre. The promotional aspects of the drug company organized meetings were disliked by a majority of respondents (58%); more of the trainers (62%) and more of those who had entered general practice within the last seven years (71%) disliked this aspect. Nonetheless the educational content of both meetings held in the practice and those held elsewhere was the aspect most liked by over half of the respondents (59% and 53% respectively). Only 16% of all respondents thought that visits by representatives from pharmaceutical companies were educationally valuable and 37% thought that educational events organized by these companies were of value. Surprisingly 60% of those who worked in practices which held meetings organized by drug company representatives thought them to be of little or no educational value. There is clearly a need for practice based continuing medical education but the current level of dependence on drug companies for organizing these meetings must be questioned. Alternative strategies for the provision of independent non-sponsored educational activities should be sought.
SN  - 0960-1643
AD  - Department of Postgraduate Studies, University of Wales College of Medicine, Cardiff.
U2  - PMID: 2282231.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107228821
T1  - Current status of professional training in the addictions.
AU  - Keller DS
AU  - Dermatis H
Y1  - 1999/09//
N1  - Accession Number: 107228821. Language: English. Entry Date: 19991201. Revision Date: 20150711. Publication Type: Journal Article; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 8808537. 
KW  - Substance Abuse -- Education
KW  - Substance Abuse -- Rehabilitation
KW  - Multidisciplinary Care Team -- Education
KW  - Certification
KW  - Psychologists
KW  - Social Workers
KW  - Physicians, Family
KW  - Psychiatry
SP  - 123
EP  - 140 18p
JO  - Substance Abuse
JF  - Substance Abuse
JA  - SUBST ABUSE
VL  - 20
IS  - 3
PB  - Taylor & Francis Ltd
AB  - Addictions training curricula within traditional graduate and postgraduate programs of professional disciplines lag behind those devoted to other disorders. After presenting a brief historical overview of addictions training in the United States, this paper focuses on current addictions training practices for each of the major health care professions, highlighting both recent advancements as well as shortcomings, particularly with respect to the ability to disseminate recent empirically tested addiction treatments. New psychosocial and pharmacotherapies for addictive disorders are then discussed which would be better disseminated within training programs with enhanced addictions training components. The paper concludes with a discussion of and recommendations for enhancing substance abuse training and knowledge dissemination.
SN  - 0889-7077
AD  - Department of Psychiatry, New York University School of Medicine, 550 First Avenue, New York, NY 10016
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108068495
T1  - Cysteinyl Leukotriene 1 Receptor Expression Associated With Bronchial Inflammation in Severe Exacerbations of COPD.
AU  - Zhu J
AU  - Bandi V
AU  - Qiu S
AU  - Figueroa DJ
AU  - Evans JF
AU  - Barnes N
AU  - Guntupalli KK
AU  - Jeffery PK
Y1  - 2012/08//
N1  - Accession Number: 108068495. Language: English. Entry Date: 20130111. Revision Date: 20150712. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Critical Care. NLM UID: 0231335. 
KW  - Bronchi -- Pathology
KW  - Pulmonary Disease, Chronic Obstructive -- Metabolism
KW  - Pulmonary Disease, Chronic Obstructive -- Pathology
KW  - RNA -- Metabolism
KW  - Receptors, Cell Surface
KW  - Receptors, Cell Surface -- Metabolism
KW  - Adult
KW  - Aged
KW  - Bronchi -- Metabolism
KW  - Case Control Studies
KW  - Prospective Studies
KW  - Female
KW  - Human
KW  - Male
KW  - Middle Age
KW  - Pulmonary Disease, Chronic Obstructive -- Etiology
KW  - Respiratory Mucosa -- Metabolism
KW  - Respiratory Mucosa -- Pathology
KW  - Smoking
KW  - Smoking -- Metabolism
SP  - 347
EP  - 357 11p
JO  - CHEST
JF  - CHEST
JA  - CHEST
VL  - 142
IS  - 2
CY  - Glenview, Illinois
PB  - American College of Chest Physicians
AB  - BACKGROUND: Cysteinyl leukotriene 1 (CysLT1) receptor expression is known to be increased in the airway mucosa of patients with asthma, especially during exacerbations; however, nothing is known of its expression in COPD. METHODS: We applied immunohistochemistry and in situ hybridization to endobronchial biopsies to determine inflammatory cell CysLT1 receptor protein and mRNA expression in the following: (1) 15 nonsmoker control subjects (NSC), (2) 16 smokers with moderate to severe COPD in its stable phase (S-COPD), and (3) 15 smokers with COPD hospitalized for a severe exacerbation (SE-COPD). RESULTS: The total number of bronchial mucosal inflammatory cells (CD45+) and those expressing CysLT1 receptor protein were significantly greater in SE-COPD (CysLT1 receptor protein: median [range] = 139 [31-634]) as compared with S-COPD (32 [6-114]) or NSC (16 [4-66]) (P .001 for both). CysLT1 receptor gene expression showed similar differences. A greater proportion of CD451 cells expressed CysLT1 receptor protein in SE-COPD (median [range] = 22% [8-81]) compared with S-COPD (10% [4-32]) (P .03) or NSC (7% [1-19]) (P .002). In SE-COPD, the relative frequencies of CysLT1 receptor-expressing cells were as follows: tryptase1 mast cells CD681 monocytes/macrophage neutrophils CD201 B lymphocytes = EG21 eosinophils. Moreover, there were positive correlations between the numbers of cells expressing CysLT1 receptor protein and the numbers of CD451 cells (r = 0.78; P .003) and tryptase1 mast cells (r = 0.62; P .02). CONCLUSIONS: Bronchial mucosal CysLT1 receptor-positive inflammatory cells are present in the bronchial mucosa in COPD in greatest number in those experiencing a severe exacerbation.From the Lung Pathology Unit, Department of Respiratory Medicine (Drs Zhu, Qiu, and Jeffery), Imperial College London, London, England; Department of Medicine (Drs Bandi and Guntupalli), Baylor College of Medicine, Ben Taub General Hospital, Houston, TX; Department of Pharmacology (Drs Figueroa and Evans), Merck & Co Inc, West Point, PA; and Department of Respiratory Medicine (Dr Barnes), Barts and The London Hospital, London, England.Correspondence to: Peter K. Jeffery, DSc, Lung Pathology, Imperial College London, Royal Brompton Hospital, Sydney St, London, SW3 6NP, England; e-mail: p.jeffery@imperial.ac.ukAuthor contributions:Dr Zhu: contributed to designing and performing the double immunostaining and in situ hybridizations, counting, data analyses, and drafting and revising the manuscript.Dr Bandi: contributed to subject recruitment, performing the bronchial biopsy, collecting relevant clinical data, and approving the manuscript.Dr Qiu: contributed to performing the immunohistochemical staining, preparing figures, and approving the manuscript.Dr Figueroa: contributed to supplying the CysLT1 receptor cDNA probe and antisera, study design, data interpretation, and approving the manuscript.Dr Evans: contributed to study design, data interpretation, and revising and approving the manuscript.Dr Barnes: contributed as co-principal investigator and approving the manuscript.Dr Guntupalli: contribute to recruiting subjects, performing the bronchial biopsy, collecting relevant clinical data and approving the manuscript.Dr Jeffery: initiated and served as the principal investigator for the study, oversaw data analysis, and revised the manuscript.Financial/nonfinancial disclosures: The authors have reported to CHEST the following conflicts of interest: Dr Figueroa was previously employed by Merck & Co Inc and is currently employed by GlaxoSmithKline. Dr Barnes has acted on Merck & Co Inc and GlaxoSmithKline advisory boards and lectured at Merck & Co Inc-sponsored symposia for which he has received remuneration. Dr Jeffery has been reimbursed by GlaxoSmithKline, AstraZeneca, and Merck & Co Inc for attending international conferences, participated as a paid speaker, and has served as a paid consultant to GlaxoSmithKline, AstraZeneca, and Argenta, and received research grants from GlaxoSmithKline, Argenta, AstraZeneca, and Merck & Co Inc, including a grant to conduct the analyses of the study presented herein. Drs Zhu, Bandi, Qiu, Evans, and Guntupalli have reported that no potential conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.Role of sponsors: The sponsors had no role in the design of the study, the collection and analysis of the data, or in the preparation of the manuscript.Other contributions: We thank Martin Spitaler, PhD, and Stephen M. Rothery, MSc (FILM, Imperial College London, London, England) for assistance with confocal microscopy.Additional information: The e-Appendix and e-Tables can be found in the 'Supplemental Materials' area of the online article.Funding/Support: This work was supported by research grants from the National Institutes of Health [Grant NO1 AI065298], Merck Sharp & Dohme Limited UK, and by departmental funds.Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.
SN  - 0012-3692
U2  - PMID: 22871757.
DO  - 10.1378/chest.11-1581
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 110526583
T1  - Demonstrating the clinical pharmacist's activity: validation of an intervention oriented classification system.
AU  - Maes, Karen
AU  - Tremp, Regina
AU  - Hersberger, Kurt
AU  - Lampert, Markus
AU  - Maes, Karen A
AU  - Tremp, Regina M
AU  - GSASA Working group on clinical pharmacy
AU  - Hersberger, Kurt E
AU  - Lampert, Markus L
Y1  - 2015/12//
N1  - Accession Number: 110526583. Language: English. Entry Date: In Process. Revision Date: 20160123. Publication Type: journal article. Journal Subset: Biomedical; Continental Europe; Europe. NLM UID: 101554912. 
SP  - 1162
EP  - 1171 10p
JO  - International Journal of Clinical Pharmacy
JF  - International Journal of Clinical Pharmacy
JA  - INT J CLIN PHARM
VL  - 37
IS  - 6
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
AB  - Background: Clinical pharmacists are increasingly involved in detecting and solving drug-related problems. To document their performance, a convenient tool to code pharmaceutical interventions in daily practice is desirable. The Swiss Society of Public Health Administration and Hospital Pharmacists (GSASA) proposed to implement a new classification system for pharmaceutical interventions.Objectives: To develop and validate a classification system for pharmaceutical interventions and to compare it with the well-established Pharmaceutical Care Network Europe (PCNE) system.Setting: Rehabilitation clinic, geriatric and orthopaedic wards of a 427-bed teaching hospital.Methods: Development of the GSASA classification started with expert panel discussions and the validation of the first version (GSASA V1). To assess appropriateness, interpretability, and validity, clinical pharmacists documented during a 6-week period all interventions using GSASA V1 and PCNE version 6.2 (V6.2). Acceptability and feasibility were tested by an 8-item questionnaire with 5-point Likert scale (1 = strongly disagree, 5 = strongly agree), and inter-rater reliability (Fleiss-Kappa coefficients κ) was determined. After revision, the second version (V2) was assessed again for reliability.Mean Outcome Measures: User's agreement/satisfaction, comprehensiveness/reliability of the classification system.Results: The GSASA V1 includes 4 categories and 35 subcategories. Of 115 interventions classified with GSASA V1, 93 (80.9 %) could be completely classified in all categories. This explains that 3 of 6 users could be not satisfied with the comprehensiveness of GSASA V1 (mean user agreement 2.7 ± 0.8). The questionnaire showed that all users could find GSASA V1 (4.0 ± 0.0) easier to use than PCNE V6.2 (3.0 ± 0.9). Users were generally satisfied with the GSASA V1 (3.5 ± 0.8), especially with the adequate time expenditure (4.0 ± 0.7). Inter-rater reliability and acceptability of GSASA V1 were comparable to those of the PCNE V6.2. The agreement among the GSASA V1 users was substantial for the categories 'problem' (κ = 0.66), 'intervention' (κ = 0.74), and 'outcome' (κ = 0.63), while moderate agreement for the category 'cause' was obtained (κ = 0.53). The final system GSASA V2 includes 5 categories (addition of 'type of problem') and 41 subcategories. Total inter-rater reliability was moderate (κ = 0.52).Conclusion: The GSASA classification system appeared to be reliable and promising for documentation of pharmaceutical interventions in daily practice (practical and less time-consuming). The system is validated in terms of appropriateness, interpretability, validity, acceptability, feasibility, and reliability.
SN  - 2210-7703
AD  - Pharmaceutical Care Research Group, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50 4056 Basel Switzerland
AD  - Pharmaceutical Care Research Group, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland
AD  - Department of Clinical Pharmacy, Kantonsspital Baselland, 4101, Bruderholz, Switzerland
U2  - PMID: 26290379.
DO  - 10.1007/s11096-015-0179-z
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107231058
T1  - Dental care of patients with substance abuse.
AU  - Bullock K
Y1  - 1999/07//1999 Jul
N1  - Accession Number: 107231058. Language: English. Entry Date: 19991201. Revision Date: 20150711. Publication Type: Journal Article; questionnaire/scale. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: CAGE Questions Adapted to Include Drugs (CAGEAID); CAGE Questionnaire. NLM UID: 0217440. 
KW  - Dental Care
KW  - Substance Abusers
KW  - Alcohol Abuse
KW  - Substance Abuse
KW  - Questionnaires
KW  - Psychological Tests
KW  - Alcohols
KW  - Cocaine
KW  - Narcotics
KW  - Hypnotics and Sedatives
KW  - Cannabis
KW  - Dentists
SP  - 513
EP  - 526 14p
JO  - Dental Clinics of North America
JF  - Dental Clinics of North America
JA  - DENT CLIN NORTH AM
VL  - 43
IS  - 3
CY  - Philadelphia, Pennsylvania
PB  - W B Saunders
AB  - Patients who abuse alcohol, crack, heroin or prescription drugs, are likely to interact with the dental professional. The dentist should therefore be able to identify problems of abuse and provide informed care and referral. Substance abuse should be a consideration in all patients who present with dental trauma and those who present with frequent vague complaints, multiple pain medication allergies, and regimens with multiple narcotic medications. Polydrug use, either prescription or illicit, is also a possibility, and effective treatment requires prompt recognition. Dentists should be alert to drug-seeking behavior within the context of pain management, and because pain severity is an objective experience, each patient must be treated carefully and sensitively. Unrelieved or unremitting pain can be a relapse trigger and therefore adequate pain control is a necessity in the recovering chemically dependent patient. New modalities, such as coanalgesia with low-dose ketamine in the opioid addicted have been shown to work effectively. In the post-dental surgical patient with chemical dependency, agents with less psychoactive activity than their drugs of abuse, such as extended-release morphine (MS Contin) have been tried with variable success. An informed treatment plan includes recognition of substance abuse, appropriate intervention, and referral. This plan may include universal screening, followed by brief interventional therapy for positive patients and in some cases, pharmacological pain control. On discharge from the office, instructions concerning referral to a substance abuse program or, in the case of the patient who may require more immediate treatment, to the emergency department are important. Copyright (c) 1999 by W.B. Saunders Company
SN  - 0011-8532
AD  - Assistant Chairperson, Providence Hospital Emergency Department, 1150 Varnum St NE, Washington, DC 20017
U2  - PMID: 10516924.
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 105794529
T1  - Depressed inpatients: treatment with psychotherapy plus pharmacotherapy superior to standard treatment.
AU  - Schwannauer M
Y1  - 2008/05//
N1  - Accession Number: 105794529. Language: English. Entry Date: 20080822. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Original Study: Schramm E, van Calker D, Dykierek P, Lieb K, Kech S, Zobel I, et al. An intensive treatment program of interpersonal psychotherapy plus pharmacotherapy for depressed inpatients: acute and long-term results. (AM J PSYCHIATRY) May2007; 164 (5): 768-777. Journal Subset: Biomedical; Europe; UK & Ireland. Special Interest: Evidence-Based Practice; Psychiatry/Psychology. NLM UID: 100883413. 
KW  - Combined Modality Therapy
KW  - Depression -- Therapy
KW  - Psychotherapy, Brief
KW  - Single-Blind Studies
SP  - 46
EP  - 46 1p
JO  - Evidence Based Mental Health
JF  - Evidence Based Mental Health
JA  - EVID BASED MENT HEALTH
VL  - 11
IS  - 2
PB  - BMJ Publishing Group
AB  - Question:Is psychotherapy better than usual clinical management for inpatients with depression who are also being treated with pharmacotherapy?Patients:130 people aged 18-65 years old with DSM-IV major depressive disorder referred for psychiatric hospitalisation, who had a score of >/= 16 on the 17-item Hamilton Depression Rating Scale (HAM-D). Exclusion criteria: bipolar I disorder, substance abuse or dependency, other primary axis I disorders, organic mental disorder, psychotic symptoms, severe cognitive impairment, active suicide ideation.Setting:Acute psychiatric hospital; enrolment November 2000 to August 2003.Intervention:Interpersonal psychotherapy (IPT) or clinical management (usual care). IPT had been adapted for an inpatient setting and included 15 individual sessions (each about 50 minutes three times weekly over 5 weeks), 8 IPT group sessions, some of which included significant others in some of the sessions. Clinical management was defined as 'psychoeducative, supportive and empathic' and involved three weekly sessions of 20-25 minutes each delivered by psychiatric residents. Both groups received pharmacotherapy (first-line treatment: sertraline; second-line treatment: amitriptyline or amitriptyline-N-oxide).Outcomes:Depressive symptoms (HAM-D) response (reduction in symptom severity of >/= 50% on HAM-D), remission (score of 7 on the HAM-D).Patient follow-up:75% completed follow-up and 95% were included in last observation carried forward analyses.METHODSDesign: Randomised controlled trial.Allocation: Concealed.Blinding: Single blind (assessors blinded).Follow-up period: Follow-up at 5 weeks with further follow-up of completers at 3 months and 12 months after treatment began.MAIN RESULTSBoth groups showed significant improvements in depression after 5 weeks (HAM-D, p<0.001), but this improvement was significantly greater in the interpersonal psychotherapy (IPT) group compared with the clinical management (CM) group (p<0.001). IPT significantly increased the proportion of people who responded by 5 weeks (70% with IPT vs 51% with CM; p = 0.043). Interpersonal psychotherapy also significantly increased the proportion of people who maintained their response at 3 and 12 months (% sustaining response at 3 months: 73% with IPT vs 47% with CM; p = 0.012; at 12 months: 69% with IPT vs 36% with CM; p = 0.002). There was no significant difference in rates of remission either at 5 weeks, or at 3 and 12 month follow up (remission by 5 weeks: 49% with IPT vs 34% with CM; p = 0.105;% sustaining remission at 3 months: 36% vs 24% with CM; at 12 months: 35% vs 20% with CM; p values reported as not significant).CONCLUSIONSBrief intensive psychotherapy plus pharmacotherapy is better than standard treatment (clinical management plus pharmacotherapy) for inpatients with depression.
SN  - 1362-0347
AD  - University of Edinburgh, Edinburgh, UK.
U2  - PMID: 18441135.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105794529&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105485250
T1  - Developing and evaluating training for community pharmacists to deliver interventions on alcohol issues.
AU  - Fitzgerald N
AU  - Watson H
AU  - McCaig D
AU  - Stewart D
Y1  - 2009/04//
N1  - Accession Number: 105485250. Language: English. Entry Date: 20090814. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Continental Europe; Europe. NLM UID: 9307352. 
KW  - Alcohol-Related Disorders -- Therapy
KW  - Education, Pharmacy
KW  - Psychotherapy, Brief -- Education
KW  - Attitude of Health Personnel
KW  - Attitude to Health
KW  - Education, Competency-Based
KW  - Pharmacy, Retail
KW  - Professional Competence
KW  - Questionnaires
KW  - Human
SP  - 149
EP  - 153 5p
JO  - Pharmacy World & Science
JF  - Pharmacy World & Science
JA  - PHARM WORLD SCI
VL  - 31
IS  - 2
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
SN  - 0928-1231
AD  - Director, Create Consultancy, Glasgow, G51 3BA, Scotland/Senior Research Fellow, School of Pharmacy, The Robert Gordon University, Schoolhill, Aberdeen, AB10 1FR, Scotland, UK.
U2  - PMID: 19199073.
DO  - 10.1007/s11096-009-9284-1
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105485250&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106765437
T1  - Development and implementation of a cross-border HIV prevention interventiion for injection drug users in Ning Ming County (Guangxi Province), China and Lang Son Province, Vietnam.
AU  - Hammett TM
AU  - Des Jarlais DC
AU  - Liu W
AU  - Ngu D
AU  - Tung ND
AU  - Hoang TV
AU  - Van LK
AU  - Donghua M
Y1  - 2003/12//
N1  - Accession Number: 106765437. Language: English. Entry Date: 20040813. Revision Date: 20150711. Publication Type: Journal Article; pictorial; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9014759. 
KW  - HIV Infections -- Prevention and Control
KW  - Needle Exchange Programs -- Methods
KW  - Program Development -- Methods
KW  - Substance Abuse, Intravenous -- Complications
KW  - Syringes -- Economics
KW  - China
KW  - Pharmacy, Retail
KW  - Vietnam
SP  - 389
EP  - 398 10p
JO  - International Journal of Drug Policy
JF  - International Journal of Drug Policy
JA  - INT J DRUG POLICY
VL  - 14
IS  - 5/6
CY  - New York, New York
PB  - Elsevier Science
AB  - This paper describes the background and early implementation of a peer-based HIV prevention intervention involving social marketing of sterile needles and syringes for injection drug users (IDUs) in a border region of northern Vietnam and southern China. Peer educators collect and safely dispose of used needles and syringes and provide IDUs with a choice of new needles/syringes or vouchers redeemable in pharmacies and clinics for new needles/syringes. The project arose from a pattern of changing drug use and increasing HIV infection in the region but its development took 4 years and faced many challenges. Implementation of the intervention posed a new set of challenges for the participating health departments, police, peer educators, pharmacists, injection drug users, and the communities at large. Early implementation of the project has revealed successful multi-sectoral collaboration, and broad acceptance by IDUs of pharmacy vouchers and distribution of new needles/syringes. However, IDUs' persistent fear of the police, particularly in Vietnam, has required reliance on separate collection by peer educators of used needles/syringes and distribution of pharmacy vouchers and new needles. In China, new needles/syringes and vouchers are largely being provided through exchange. Understanding the development and implementation challenges and the strategies that were successful in overcoming them (including the importance of being flexible and adaptable to contextual factors) may be useful to those interested in launching similar, much-needed interventions in other parts of the world.
SN  - 0955-3959
AD  - Abt Associates Inc., 55 Wheeler Street, Cambridge, MA 02138-1168; ted_hammettt@abtassoc.com
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106761377
T1  - Development and implementation of a tobacco cessation training program for students in the health professions.
AU  - Hudmon KS
AU  - Corelli RL
AU  - Chung E
AU  - Gundersen B
AU  - Kroon LA
AU  - Sakamoto LM
AU  - Hemberger KK
AU  - Fenlon C
AU  - Prokhorov AV
Y1  - 2003///2003 Fall
N1  - Accession Number: 106761377. Language: English. Entry Date: 20040730. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Health Promotion/Education; Peer Reviewed; USA. Grant Information: California Dept of Health Tobacco Control Section (grant 94-20949-02), the University of California Tobacco-Related Disease Research Program (grants 10ST-0339 and 8BT-2301) and the University of California Instructional Improvement Grants Program (grant cycle 2000-2001). NLM UID: 8610343. 
KW  - Counseling -- Education
KW  - Curriculum
KW  - Education, Pharmacy
KW  - Smoking Cessation -- Education
KW  - Students, Pharmacy
KW  - Adult
KW  - Age Factors
KW  - Asians
KW  - Behavior Modification
KW  - Blacks
KW  - California
KW  - Coefficient Alpha
KW  - Colleges and Universities
KW  - Competency Assessment
KW  - Course Evaluation
KW  - Descriptive Statistics
KW  - Education Research
KW  - Evaluation Research
KW  - Factor Analysis
KW  - Female
KW  - Hispanics
KW  - Internal Consistency
KW  - Lecture
KW  - Male
KW  - Middle Age
KW  - Practice Guidelines
KW  - Pretest-Posttest Design
KW  - Prospective Studies
KW  - Race Factors
KW  - Scales
KW  - Seminars and Workshops
KW  - Sex Factors
KW  - Summated Rating Scaling
KW  - Surveys
KW  - T-Tests
KW  - Teaching Materials
KW  - Teaching Methods
KW  - Whites
KW  - Funding Source
KW  - Human
SP  - 142
EP  - 149 8p
JO  - Journal of Cancer Education
JF  - Journal of Cancer Education
JA  - J CANCER EDUC
VL  - 18
IS  - 3
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
AB  - BACKGROUND: A comprehensive tobacco cessation training program, Rx for Change, was developed and implemented as required coursework at all California schools of pharmacy and at the University of California San Francisco Schools of Medicine and Dentistry. RESULTS: Post-training evaluations administered to pharmacy students (n = 544; 89% participation) show a positive impact of the training on students' self-reported abilities for providing tobacco cessation counseling to patients. CONCLUSION: Designed as a vehicle for nationwide dissemination of the U.S. Public Health Service Clinical Practice Guideline for Treating Tobacco Use and Dependence, Rx for Change equips students with skills to intervene with all tobacco users, including patients who are not yet considering quitting.
SN  - 0885-8195
AD  - School of Pharmacy, University of California San Francisco, 3333 California St, Suite 420, San Francisco, CA 94118; khudmon@itsa.ucsf.edu
U2  - PMID: 14512261.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106761377&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109735847
T1  - Development of clinical pharmacy key performance indicators for hospital pharmacists using a modified Delphi approach.
AU  - Fernandes, Olavo
AU  - Gorman, Sean K
AU  - Slavik, Richard S
AU  - Semchuk, William M
AU  - Shalansky, Steve
AU  - Bussières, Jean-François
AU  - Doucette, Douglas
AU  - Bannerman, Heather
AU  - Lo, Jennifer
AU  - Shukla, Simone
AU  - Chan, Winnie W Y
AU  - Benninger, Natalie
AU  - MacKinnon, Neil J
AU  - Bell, Chaim M
AU  - Slobodan, Jeremy
AU  - Lyder, Catherine
AU  - Zed, Peter J
AU  - Toombs, Kent
Y1  - 2015/06//
N1  - Accession Number: 109735847. Language: English. Entry Date: 20150923. Revision Date: 20151105. Publication Type: journal article. Journal Subset: Biomedical; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9203131. 
SP  - 656
EP  - 669 14p
JO  - Annals of Pharmacotherapy
JF  - Annals of Pharmacotherapy
JA  - ANN PHARMACOTHER
VL  - 49
IS  - 6
CY  - Thousand Oaks, California
PB  - Sage Publications Inc.
AB  - Background: Key performance indicators (KPIs) are quantifiable measures of quality. There are no published, systematically derived clinical pharmacy KPIs (cpKPIs).Objective: A group of hospital pharmacists aimed to develop national cpKPIs to advance clinical pharmacy practice and improve patient care.Methods: A cpKPI working group established a cpKPI definition, 8 evidence-derived cpKPI critical activity areas, 26 candidate cpKPIs, and 11 cpKPI ideal attributes in addition to 1 overall consensus criterion. Twenty-six clinical pharmacists and hospital pharmacy leaders participated in an internet-based 3-round modified Delphi survey. Panelists rated 26 candidate cpKPIs using 11 cpKPI ideal attributes and 1 overall consensus criterion on a 9-point Likert scale. A meeting was facilitated between rounds 2 and 3 to debate the merits and wording of candidate cpKPIs. Consensus was reached if 75% or more of panelists assigned a score of 7 to 9 on the consensus criterion during the third Delphi round.Results: All panelists completed the 3 Delphi rounds, and 25/26 (96%) attended the meeting. Eight candidate cpKPIs met the consensus definition: (1) performing admission medication reconciliation (including best-possible medication history), (2) participating in interprofessional patient care rounds, (3) completing pharmaceutical care plans, (4) resolving drug therapy problems, (5) providing in-person disease and medication education to patients, (6) providing discharge patient medication education, (7) performing discharge medication reconciliation, and (8) providing bundled, proactive direct patient care activities.Conclusions: A Delphi panel of hospital pharmacists was successful in determining 8 consensus cpKPIs. Measurement and assessment of these cpKPIs will serve to advance clinical pharmacy practice and improve patient care.
SN  - 1060-0280
U2  - PMID: 25780250.
DO  - 10.1177/1060028015577445
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105822619
T1  - Development of innovative teaching materials: clinical pharmacology problem-solving (CPPS) units: comparison with patient-oriented problem-solving units and problem-based learning--a 10-year review.
AU  - Lathers CM
AU  - Smith CM
Y1  - 2002/05//
N1  - Accession Number: 105822619. Language: English. Entry Date: 20080307. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0366372. 
KW  - Pharmacy and Pharmacology -- Education
KW  - Problem-Based Learning
KW  - Teaching
KW  - Anticonvulsants
KW  - Education, Medical
KW  - Education, Pharmacy
KW  - Eye Diseases
KW  - Geriatrics -- Education
KW  - Glaucoma
KW  - Netherlands
KW  - Osteopathy -- Education
KW  - Patients
KW  - Program Evaluation
KW  - United States
SP  - 477
EP  - 491 15p
JO  - Journal of Clinical Pharmacology
JF  - Journal of Clinical Pharmacology
JA  - J CLIN PHARMACOL
VL  - 42
IS  - 5
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - The First Teaching Clinic in Clinical Pharmacology, sponsored by the American College of Clinical Pharmacology in September 1992, was designed for the preparation and development of new clinical pharmacology problem-solving (CPPS) units. CPPS units are case histories that illustrate pertinent principles in clinical pharmacology. Each unit consists of the following sections: introduction, learning objectives, pretest, four clinical pharmacology scenarios, posttest, answers to pre- and posttest questions, and selected references. The clinical pharmacology content of the CPPS units place greater emphasis on clinical information, drug selection, and risk/benefit analyses, and thus they complement the basic pharmacology presented in the patient-oriented problem-solving (POPS) units. In general, the CPPS units are intended for use by students more advanced in clinical pharmacology than first- and second-year medical students. The CPPS unit 'Clinical Pharmacology of Antiepileptic Drug Use: Clinical Pearls about the Perils of Patty' was developed for use by third- and fourth-year medical students doing rotations in neurology or clinical pharmacology; advanced pharmacy students; residents in neurology, pediatrics, internal medicine, and family practice; fellows in clinical pharmacology, and those taking the board examination in clinical pharmacology. The CPPS unit titled 'Geriatric Clinical Psychopharmacology' was written for third- and fourth-year medical students; residents in psychiatry, family practice, and internal medicine;fellows in clinical pharmacology; and those studying for boards in clinical pharmacology. The CPPS unit 'Anisocoria and Glaucoma' was written for more advanced students of clinical pharmacology. The CPPS unit titled 'Antiepileptic Drugs' was intended for second-year medical students. The second teaching clinic was held in November 1993 and focused on the development and editing of the CPPS units and their evaluations by faculty and students from academic centers. Evaluations by faculty and students have been overwhelmingly positive. Requests to use the CPPS units in various clinical pharmacology teaching programs were received from numerous schools within the United States and from abroad. The third teaching clinic in September 1995 included a follow-up focused on the uses of drug information databases in case problem exercises. These examples are presented to demonstrate the variety of educational activities the American College of Clinical Pharmacology is sponsoring to fulfill its strategic initiative dedicated to offer innovative teaching programs and to develop new teaching materials in clinical pharmacology. Collectively, all of the teaching clinics, symposia, and workshop efforts, sponsored by the various academic professional societies alone or together over the past decade, are necessary if new and innovative teaching materials in the field of basic science and in the fields of pharmacology and clinical pharmacology are to be continuously developed to keep pace with the new, rapidly changing developments in medicine to provide the best treatment for patients in the 21st century.
SN  - 0091-2700
AD  - U.S. Food and Drug Administration, Office of New Animal Drug Evaluation, Center for Veterinary Medicine, Rockville, Maryland 20855, USA.
U2  - PMID: 12017342.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108008880
T1  - Dextromethorphan Abuse: A Literature Review.
AU  - Jennifer A Gershman
AU  - Andrea D Fass
Y1  - 2013/03//2014 Aug
N1  - Accession Number: 108008880. Language: English. Entry Date: 20140926. Revision Date: 20150712. Publication Type: Journal Article; review. Journal Subset: Biomedical; Blind Peer Reviewed; Double Blind Peer Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Public Health. NLM UID: 8504643. 
KW  - Antitussive Agents
KW  - Dextromethorphan
KW  - Dose-Response Relationship
KW  - Patient Education
KW  - Substance Abuse -- Symptoms
KW  - Costs and Cost Analysis
KW  - Pharmacists
KW  - Professional Role
SP  - 66
EP  - 71 6p
JO  - Journal of Pharmacy Technology
JF  - Journal of Pharmacy Technology
JA  - J PHARM TECHNOL
VL  - 30
IS  - 4
CY  - Thousand Oaks, California
PB  - Sage Publications Inc.
AB  - Objective: To review dextromethorphan abuse patterns from 2002-2012 and emphasize the pharmacist's role in prevention, education, and sales surveillance. Data Sources: A literature search was conducted through PubMed (2002-November 2012), EMBASE (2002- November 2012), and International Pharmaceutical Abstracts (2002-November 2012), using the search term dextromethorphan abuse. The Drug Enforcement Administration and National Association of Boards of Pharmacy websites were searched for dextromethorphan abuse and legislative updates. The search was limited to a 10-year period to identify the most current case reports and studies. Study Selection and Data Extraction: The limits used were studies/case reports evaluating humans and published in the English language. Only studies and case reports that assessed dextromethorphan abuse were included in the review. Eight studies and 9 case reports met the inclusion criteria. Data Synthesis: Case reports and studies demonstrate that there are patterns associated with dextromethor phan abuse. A study using data reported to the National Poison Data System identified Coricidin as the most (65.5%) commonly abused dextromethorphan product until 2006; its abuse has decreased since that time (p < 0.0001). The most common abuse effects and toxicities cited in studies and case reports include agitation, confusion, central nervous system depression, tachycardia, hypertension, lethargy, psychosis, hallucinations, mydriasis, dizziness, and cardiotoxicity. One study identified that 96% of samples tested positive for other substances in addition to dextromethorphan. Coingestion of other substances is also common among dextromethorphan abusers. CONCLUSIONS: Case reports and studies demonstrate that there are patterns associated with dextromethorphan abuse. It is difficult to identify dextromethorphan as the causative agent of abuse effects because of coingestion of other substances. Studies should examine the pharmacist's role and the association between dextromethorphan sales restrictions and abuse patterns.
SN  - 8755-1225
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106731227
T1  - Diagnosis and management of post-traumatic stress disorder...adapted with permission from American Psychiatric Association. Diagnostic and statistical manual of mental disorders, fourth edition, text revision. Washington, D.C.: American Psychiatric Association, 2000:467-8. Copyright 2000
AU  - Grinage BD
Y1  - 2003/12/15/
N1  - Accession Number: 106731227. Language: English. Entry Date: 20040507. Revision Date: 20150711. Publication Type: Journal Article; algorithm; CEU; consumer/patient teaching materials; exam questions; tables/charts. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 1272646. 
KW  - Stress Disorders, Post-Traumatic -- Diagnosis
KW  - Stress Disorders, Post-Traumatic -- Therapy
KW  - Adult
KW  - Comorbidity
KW  - Diagnosis, Psychosocial
KW  - Education, Continuing (Credit)
KW  - Female
KW  - Male
KW  - Mental Disorders
KW  - Middle Age
KW  - Patient Education
KW  - Psychotherapy
KW  - Stress Disorders, Post-Traumatic -- Drug Therapy
KW  - Stress Disorders, Post-Traumatic -- Etiology
KW  - Stress Disorders, Post-Traumatic -- Psychosocial Factors
KW  - Stress Disorders, Post-Traumatic -- Risk Factors
KW  - Trauma -- Psychosocial Factors
KW  - United States
SP  - 2401
EP  - 2460 13p
JO  - American Family Physician
JF  - American Family Physician
JA  - AM FAM PHYSICIAN
VL  - 68
IS  - 12
CY  - Skokie, Illinois
PB  - American Academy of Family Physicians
AB  - Although post-traumatic stress disorder (PTSD) is a debilitating anxiety disorder that may cause significant distress and increased use of health resources, the condition often goes undiagnosed. The lifetime prevalence of PTSD in the United States is 8 to 9 percent, and approximately 25 to 30 percent of victims of significant trauma develop PTSD. The emotional and physical symptoms of PTSD occur in three clusters: re-experiencing the trauma, marked avoidance of usual activities, and increased symptoms of arousal. Before a diagnosis of PTSD can be made, the patient's symptoms must significantly disrupt normal activities and last for more than one month. Approximately 80 percent of patients with PTSD have at least one comorbid psychiatric disorder. The most common comorbid disorders include depression, alcohol and drug abuse, and other anxiety disorders. Treatment relies on a multidimensional approach, including supportive patient education, cognitive behavior therapy, and psychopharmacology. Selective serotonin reuptake inhibitors are the mainstay of pharmacologic treatment.
SN  - 0002-838X
AD  - University of Kansas School of Medicine-Wichita, Department of Psychiatry and Behavioral Sciences, 1010 N Kansas, Wichita, KS 67214-3199; bgrinage@kumc.edu
U2  - PMID: 14705759.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106731227&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105765141
T1  - Diagnosis and treatment of insomnia.
AU  - Passarella S
AU  - Duong MT
Y1  - 2008/05/15/
N1  - Accession Number: 105765141. Language: English. Entry Date: 20080711. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Insomnia -- Diagnosis
KW  - Insomnia -- Therapy
KW  - Antianxiety Agents, Benzodiazepine -- Therapeutic Use
KW  - Cognitive Therapy
KW  - Hypnotics and Sedatives -- Therapeutic Use
KW  - Insomnia -- Drug Therapy
KW  - Psychotropic Drugs -- Therapeutic Use
KW  - Receptors, Cell Surface
SP  - 927
EP  - 934 8p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 65
IS  - 10
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
AB  - PURPOSE: The diagnostic criteria and treatment of insomnia are reviewed. SUMMARY: Insomnia is most often described as a subjective complaint of poor sleep quality or quantity despite adequate time for sleep, resulting in daytime fatigue, irritability, and decreased concentration. Insomnia is classified as idiopathic or comorbid. Comorbid insomnias are associated with psychiatric disorders, medical disorders, substance abuse, and specific sleep disorders. Idiopathic insomnia is essentially a diagnosis of exclusion. A wide array of terminology exists for defining the duration of insomnia symptoms, which may add to the confusion regarding insomnia classification. Acute insomnia refers to sleep problems lasting from one night to a few weeks, whereas chronic insomnia refers to sleep problems lasting at least three nights weekly for at least one month. Diagnostic tools for identifying insomnia are multifactorial. Nonpharmacologic interventions for insomnia include sleep-hygiene education, stimulus-control therapy, relaxation therapy, and sleep-restriction therapy. The most effective pharmacologic therapies for insomnia are benzodiazepines, benzodiazepine-receptor agonists, melatonin-receptor agonists, and antidepressants. Choice of a specific agent should be based on patient-specific factors, including age, proposed length of treatment, primary sleep complaint, history of drug or alcohol abuse, and cost. CONCLUSION: Many treatment options are available for patients with insomnia. Behavioral therapies should be initiated as first-line treatment in most patients. For patients who require the addition of pharmacologic therapy, the drugs with the most evidence for benefit include benzodiazepines, benzodiazepine-receptor agonists, melatonin-receptor agonists, and antidepressants. Selection of a specific agent must take into account numerous patient-specific factors.
SN  - 1079-2082
AD  - Pharmacy Department, Tampa General Hospital, Tampa, FL 33601, USA. spassarella@tgh.org
U2  - PMID: 18463341.
DO  - 10.2146/ajhp060640
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106793065
T1  - Disease management opportunities for chronic obstructive pulmonary disease: gaps between guidelines and current practice.
AU  - Feifer RA
AU  - Aubert R
AU  - Verbrugge RR
AU  - Khalid M
Y1  - 2002/09//
N1  - Accession Number: 106793065. Language: English. Entry Date: 20030103. Revision Date: 20150820. Publication Type: Journal Article; research; tables/charts. Journal Subset: Health Services Administration; Peer Reviewed; USA. Instrumentation: AQ30 Instrument for Assessing Respiratory QOL; St. George's Respiratory Questionnaire (SGRQ). NLM UID: 9802539. 
KW  - Pulmonary Disease, Chronic Obstructive
KW  - Disease Management
KW  - Questionnaires
KW  - Self Report
KW  - Quality of Life
KW  - Chi Square Test
KW  - Drug Utilization
KW  - Health Resource Utilization
KW  - Data Analysis, Statistical
KW  - Data Analysis Software
KW  - Descriptive Statistics
KW  - P-Value
KW  - Productivity
KW  - Smoking -- Epidemiology
KW  - Immunization -- Trends
KW  - Pulmonary Disease, Chronic Obstructive -- Education
KW  - Patient Education
KW  - Middle Age
KW  - Aged
KW  - Aged, 80 and Over
KW  - Male
KW  - Female
KW  - Human
SP  - 143
EP  - 156 14p
JO  - Disease Management
JF  - Disease Management
JA  - DIS MANAGE
VL  - 5
IS  - 3
CY  - New Rochelle, New York
PB  - Mary Ann Liebert, Inc.
AB  - Chronic obstructive pulmonary disease (COPD) is a highly prevalent condition with broad economic impacts. It presents a major opportunity for healthcare cost reduction and improved functional status. This study measures the gaps between current treatment practices and recently issued guidelines, and identifies the primary opportunities for COPD disease management. COPD patients (n = 1,036) were initially identified using pharmacy claims data on outpatient respiratory medication use. Through a health assessment survey, they confirmed their diagnosis and reported on their medical resource use, vaccinations, smoking, and healthrelated quality of life (QOL). Drug utilization was measured using a 12-month retrospective review of prescription claims. Patients were stratified by severity level based on QOL scores. A large subset of patients (25.7%) did not use inhaled bronchodilators, the preferred first-line therapy in COPD guidelines; instead, these patients used oral bronchodilators (8.1%) or no bronchodilator at all (17.6%). Inhaled corticosteroids (ICSs) were used by 54.8% of patients. Many patients had not received an influenza vaccination during the previous year (20.7%) or a pneumococcal vaccination during their lifetime (28.3%). Some patients continue to smoke on a regular basis (11.8%). A majority of patients reported that they do not feel knowledgeable about their disease (52.2%) or therapy (53.2%). In summary, significant gaps exist between COPD treatment guidelines and clinical practice, including underuse of inhaled bronchodilators, extensive use of ICSs, and underuse of vaccinations. To reduce the condition's clinical and economic impacts, COPD disease management programs need to target four key areas: pharmacotherapy, vaccination rates, smoking cessation, and patient education.
SN  - 1093-507X
AD  - Department of Medical Affairs, Medco Health, 100 Parsons Pond Drive, F2-2, Franklin Lakes, NJ 07417; richard_feifer@medcohealth.com
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106793065&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109623546
T1  - Diversion of opioid maintenance treatment medications and predictors for diversion among Finnish maintenance treatment patients.
AU  - Launonen, Essiina
AU  - Alho, Hannu
AU  - Kotovirta, Elina
AU  - Wallace, Isla
AU  - Simojoki, Kaarlo
Y1  - 2015/09//
N1  - Accession Number: 109623546. Language: English. Entry Date: 20150923. Revision Date: 20151028. Publication Type: journal article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9014759. 
SP  - 875
EP  - 882 8p
JO  - International Journal of Drug Policy
JF  - International Journal of Drug Policy
JA  - INT J DRUG POLICY
VL  - 26
IS  - 9
CY  - New York, New York
PB  - Elsevier Science
AB  - Background: Diversion (i.e. selling or giving away) of opioid maintenance treatment (OMT) medications is a challenge that concerns many units providing OMT worldwide and tools for prevention are needed. The object of this study was to examine the prevalence and predictors for diversion of the OMT medications buprenorphine-naloxone (BNX) and methadone (MET) among Finnish OMT patients.Methods: A cross-sectional study was conducted among all Finnish OMT patients of whom 60% (n=1508) participated. The data were collected by anonymous questionnaires distributed through all OMT units in Finland. To evaluate predictors for diversion, we used binominal regression analysis with unadjusted and adjusted ORs. Selling and/or giving away of OMT medication was used as a dependent variable and explanatory variables were gender, age, duration of OMT, type of OMT medication and dose, dispensation method of OMT medication, place of residence and intravenous use of any intoxicating drugs during the past six months.Results: Of all 1508 respondents, 7% (n=100) had sold and 12% (n=169) had given their OMT medication to others, 57% for money and 23% in exchange for other drugs. In multivariate analysis, predictors associated with diversion were BNX as OMT medication (OR 2.76, 95% CI 1.76-4.33), low (<9.0mg/day) BNX dose (OR 1.74, 95% CI 1.01-2.98), intravenous use of intoxicating drugs during the past six months (OR 4.48, 95% CI 3.13-6.43) and increasing length of OMT (OR 1.01, 95% CI 1.01-1.02). Age, place of residence or unsupervised pharmacy distribution of BNX were not associated with diversion.Conclusions: In order to reduce diversion, more interventions are needed to support patients to stop concurrent substance abuse. Increasing control measures, for example, increased supervision, are unlikely to prevent diversion. Given that sub-optimal dosing of BNX increases the risk of diversion, more attention should be paid to providing patients with an optimal medical dose.
SN  - 0955-3959
U2  - PMID: 25934054.
DO  - 10.1016/j.drugpo.2015.03.007
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106883221
T1  - Does knowledge count? Attitudes toward smoking among medical, nursing, and pharmacy students in Hungary.
AU  - Piko BF
Y1  - 2002/08//
N1  - Accession Number: 106883221. Language: English. Entry Date: 20031107. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; Public Health; USA. NLM UID: 7600747. 
KW  - Smoking -- Psychosocial Factors
KW  - Student Attitudes
KW  - Students, Medical
KW  - Students, Nursing
KW  - Students, Pharmacy
KW  - Adolescence
KW  - Adult
KW  - Chi Square Test
KW  - Data Analysis Software
KW  - Health Beliefs
KW  - Hungary
KW  - Kappa Statistic
KW  - Questionnaires
KW  - Test-Retest Reliability
KW  - Human
SP  - 269
EP  - 276 8p
JO  - Journal of Community Health
JF  - Journal of Community Health
JA  - J COMMUNITY HEALTH
VL  - 27
IS  - 4
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
AB  - Despite the fact that cigarette smoking in East Europe is a major health problem, no effective health policy responses have been developed thus far. Health care professionals represent a valuable resource for tobacco control. Therefore, we wanted to obtain information about the acceptance of smoking among medical, nursing and pharmacy students (n = 270) in Szeged, Hungary. The self-administered questionnaire contained items on smoking behavior, beliefs and attitudes related to smoking. Chi2-test were used to determine differences in the attitudes among students. Smoking was the most frequent among nursing students, followed by medical students. Pharmacy students not only reported smoking the least but they also showed the most acceptable attitudes toward smoking. The high frequency of smoking among students suggests that they themselves are unable to cope with avoiding the dangers of smoking. Moreover, responses reflect a generally poor appreciation of responsibility that health care professionals have in prevention. There is a need for an increasing emphasis on smoking-related attitude formation among medical and nursing students.
SN  - 0094-5145
AD  - Associate Professor of Medical Sociology and Community Medicine, Department of Psychiatry, Group of Behavioral Sciences, University of Szeged, 5 Szentháromság Street, Szeged, Hungary 6722; pikobettina@yahoo.com
U2  - PMID: 12190055.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104163362
T1  - Does recovery-oriented treatment prompt heroin users prematurely into detoxification and abstinence programmes? Qualitative study.
AU  - Neale J
AU  - Nettleton S
AU  - Pickering L
Y1  - 2013/01//
N1  - Accession Number: 104163362. Language: English. Entry Date: 20131220. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology. NLM UID: 7513587. 
KW  - Substance Use Disorders -- Epidemiology
KW  - Substance Use Disorders -- Therapy
KW  - Recovery
KW  - Substance Use Rehabilitation Programs -- Standards
KW  - Adult
KW  - Female
KW  - Prospective Studies
KW  - Substance Use Disorders -- Psychosocial Factors
KW  - Human
KW  - Male
KW  - Middle Age
KW  - Substance Use Rehabilitation Programs -- Methods
KW  - Treatment Outcomes
KW  - Young Adult
SP  - 163
EP  - 169 7p
JO  - Drug & Alcohol Dependence
JF  - Drug & Alcohol Dependence
JA  - DRUG ALCOHOL DEPENDENCE
VL  - 127
IS  - 1-3
PB  - Elsevier Science
AB  - AIMS: (i) To consider whether or not recovery-oriented treatment might be prompting heroin users prematurely into detoxification and abstinence programmes; (ii) to explore the findings with reference to Foucauldian theory. METHODS: Longitudinal qualitative data comprising 57 audio-recorded interviews, which captured heroin users' views and experiences of treatment duration. Participants included 30 heroin users (15 men; 15 women) starting a new episode of treatment, of whom 27 (14 men; 13 women) were re-interviewed after 3 months. Recruitment occurred in community drug services, pharmacies and residential treatment settings in Southern England, UK. Transcribed data were systematically coded and analysed inductively. FINDINGS: All participants wanted to be free from heroin and prescribed substitute drugs. Individuals were often impatient with the detoxing process and some reduced dosages of substitute medication faster than prescribers recommended, occasioning cross addiction and relapse. Previously unsuccessful rapid detoxifications induced slower recovery attempts. Participation in residential rehabilitation facilitated client realisation that recovery required time and effort. CONCLUSIONS: Recovery-oriented treatment can prompt heroin users prematurely into detoxification and abstinence programmes with negative consequences. The desire to detoxify quickly can be interpreted through Foucault's concepts of 'self-governance' and 'resistance;' heroin users' participation in decision-making processes reflects notions of 'agency;' and clients' willingness to adopt longer approaches to recovery following past negative detoxification experiences and exposure to residential rehabilitation confirms their commitment to be 'well.' The experiential knowledge of heroin users who have personally attempted recovery is a crucial resource for both those contemplating their own recovery and those advocating recovery-oriented services.
SN  - 0376-8716
AD  - Faculty of Health & Life Sciences, Oxford Brookes University, Jack Straw's Lane, Marston, Oxford OX3 0FL UK; National Centre in HIV Social Research, Faculty of Arts and Social Sciences, Level 3 John Goodsell Building, University of New South Wales, Sydney, NSW 2052 Australia. Electronic address: jneale@brookes.ac.uk.
U2  - PMID: 22809895.
DO  - 10.1016/j.drugalcdep.2012.06.030
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106409630
T1  - Does smoking affect blood pressure and heart rate?
AU  - Al-Safi SA
Y1  - 2005/12//
N1  - Accession Number: 106409630. Language: English. Entry Date: 20060317. Revision Date: 20150820. Publication Type: Journal Article; research; tables/charts. Journal Subset: Continental Europe; Europe; Nursing; Peer Reviewed. NLM UID: 101128793. 
KW  - Blood Pressure
KW  - Heart Rate
KW  - Smoking
KW  - Adult
KW  - Correlational Studies
KW  - Cross Sectional Studies
KW  - Descriptive Statistics
KW  - Dose-Response Relationship
KW  - Female
KW  - Interviews
KW  - Jordan
KW  - Male
KW  - Middle Age
KW  - Unpaired T-Tests
KW  - Human
SP  - 286
EP  - 289 4p
JO  - European Journal of Cardiovascular Nursing
JF  - European Journal of Cardiovascular Nursing
JA  - EUR J CARDIOVASC NURS
VL  - 4
IS  - 4
PB  - Sage Publications, Ltd.
AB  - BACKGROUND: Smoking is a risk factor for cardiovascular, coronary artery and thromboembolic disorders. There is overwhelming evidence supporting the association of cigarette smoking and the development of cardiovascular and thromboembolic events particularly in high risk populations. AIM: The aim of this investigation was to explore the correlation of smoking habit with blood pressure and heart rate values through a randomized cross-sectional epidemiological study in Jordan. SETTINGS AND DESIGN: This study was performed during the period of February-June 2004. The sample of this investigation included healthy adult males and females from various regions of Jordan. Most of the selected sample included Jordanian university students. Patients with hypertension or cardiovascular disorders were excluded. METHODS: Selected individuals of the sample were interviewed by well-trained senior pharmacy students. They were asked initially if they have hypertension or other cardiovascular disorders and if the answer was negative, further questions were asked followed by measurement of the blood pressure and heart rate. Demographic data such as age, sex, nationality, place of residence, occupation and level of education were also recorded. Smokers (for > or =6 months) were asked to report how many cigarettes per day they smoke. For each individual of the sample, the systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate were measured three times with 10-15 min intervals in the sitting position and at the resting state. The arterial blood pressure (ABP) was calculated from the measured SBP and DBP. The mean values were distributed according to sex and smoking habit. STATISTICAL ANALYSIS: The student unpaired t-test was used for statistical analysis. Results were considered statistically significant when the p value was less than 0.05. RESULTS AND CONCLUSION: A total of 14,310 adult males (7400) and females (6910) were selected in various regions of Jordan. The frequencies of smokers and non-smokers in the sample were 3832 (26.8%) and 10478 (73.2%), respectively. Smoker males and females had significantly higher SBP, DBP, ABP values than non-smokers. However, smoking had statistically non-significant effects on heart rate in females while heart rate values were significantly higher in male smokers than in non-smokers. Smoker or non-smoker adults with a positive family history of hypertension had significantly higher blood pressure and heart rate values than those with a negative family history of hypertension. In conclusion, smokers have higher blood pressure than non-smokers.
SN  - 1474-5151
AD  - Dept of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, PO Box 3030, Irbid 22110, Jordan; alsafi52@yahoo.com
U2  - PMID: 16332506.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106409630&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104132813
T1  - Does training in motivational interviewing for community pharmacists improve outcomes for methadone patients? A cluster randomised controlled trial.
AU  - Jaffray, Mariesha
AU  - Matheson, Catriona
AU  - Bond, Christine M.
AU  - Lee, Amanda J.
AU  - McLernon, David J.
AU  - Johnstone, Allan
AU  - Skea, Lucy
AU  - Davidson, Bruce
Y1  - 2014/02//
N1  - Accession Number: 104132813. Language: English. Entry Date: 20140116. Revision Date: 20150710. Publication Type: Journal Article; clinical trial; research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice. 
KW  - Communities
KW  - Pharmacists -- Education
KW  - Motivational Interviewing -- Methods
KW  - Methadone -- Administration and Dosage
KW  - Patient Care
KW  - Pharmacy and Pharmacology
KW  - Human
KW  - Clinical Trials
KW  - Outcomes (Health Care)
KW  - Scotland
KW  - Research Subject Recruitment
KW  - Heroin -- Administration and Dosage
KW  - Street Drugs
KW  - Adult
KW  - Male
KW  - Female
KW  - Employment
KW  - Heroin -- Adverse Effects
KW  - Substance Abuse -- Therapy
KW  - After Care
KW  - Substance Abusers
SP  - 4
EP  - 12 9p
JO  - International Journal of Pharmacy Practice
JF  - International Journal of Pharmacy Practice
JA  - INT J PHARM PRACT
VL  - 22
IS  - 1
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 0961-7671
AD  - Division of Applied Medicine (Psychiatry), University of Aberdeen
AD  - Centre of Academic Primary Care, University of Aberdeen
AD  - Medical Statistics Team, Division of Applied Health Sciences, University of Aberdeen
AD  - Advantage Training Consultancy
AD  - Substance Misuse, NHS Grampian
DO  - 10.1111/ijpp.12049
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105819470
T1  - Doping control in sports--a perspective from the 1996 Olympic Games.
AU  - Ambrose PJ
Y1  - 1997/05//1997 May 1
N1  - Accession Number: 105819470. Language: English. Entry Date: 20080307. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Doping in Sports -- Prevention and Control
KW  - Mandatory Testing -- Administration
KW  - Sports Medicine
KW  - Sports
KW  - Substance Abuse Detection
KW  - Georgia
SP  - 1053
EP  - 1057 5p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 54
IS  - 9
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
AB  - Doping-control (DC) procedures, particularly as used at the 1996 Olympic Games, are described, and the role of pharmacists in DC is discussed. DC procedures must be strict and precisely followed to avoid contamination of samples, the appearance of bias, and breaches in security and confidentiality. The process of selecting athletes for testing can be random, nonrandom, or a combination of the two. Escorts are used to notify athletes of their selection, verify their identity, and accompany them to the DC station. When urine specimens are obtained for DC, the voiding process must be directly observed. The specimen is checked for pH and specific gravity and then processed for shipping to a laboratory to be analyzed for banned substances. Medication histories are also obtained, giving athletes the opportunity to declare any substance that has been taken for legitimate medical purposes. Laboratory analysis involves screening and confirmation phases. During the Atlanta Games, roughly 50 pharmacists participated in the DC program as escorts or technical officers. It is logical to involve pharmacists in DC programs because they can develop and conduct drug-testing protocols; educate athletes, coaches, and trainers about drug use and abuse; and help ensure the safe and effective use of medications. Sophisticated doping-control procedures have been developed for athletic competitions, and pharmacists have much to offer DC programs.
SN  - 1079-2082
AD  - Pharmacokinetics Service, Long Beach Memorial Medical Center, CA 90801-1428, USA.
U2  - PMID: 9143653.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105819470&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108099178
T1  - Drug Abuse Liability Assessment: A Review.
AU  - Balhara, Yatan Pal Singh
Y1  - 2012/09//
N1  - Accession Number: 108099178. Language: English. Entry Date: 20121130. Revision Date: 20150712. Publication Type: Journal Article; review. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Psychiatry/Psychology. NLM UID: 101148822. 
KW  - Drugs -- Adverse Effects
KW  - Liability, Legal -- Evaluation
KW  - Risk Assessment
KW  - Substance Abuse -- Prevention and Control
KW  - Substance Abuse -- Risk Factors
KW  - Animal Studies
KW  - Clinical Assessment Tools
KW  - Consent
KW  - Research Methodology
KW  - Study Design
SP  - 123
EP  - 135 13p
JO  - Addictive Disorders & Their Treatment
JF  - Addictive Disorders & Their Treatment
JA  - ADDICT DISORD THEIR TREAT
VL  - 11
IS  - 3
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - Assessment of abuse liability of drugs is an important area of biomedical research. It has important implications ranging from physician education to regulatory control of different pharmacological compounds. One needs to be aware of the recommended paradigms while indulging in such research. Selection of appropriate methodology and study design would help answer the question definitively. There are different recommendations to carry out such research. The choice of the methodology should be driven by recommendations and need of the particular paradigm.
SN  - 1531-5754
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104719015
T1  - Drug anticipation and drug addiction. The 1998 H. David Archibald Lecture.
AU  - Siegel, S
Y1  - 1999/08//
N1  - Accession Number: 104719015. Language: English. Entry Date: 20110610. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9304118. 
KW  - Conditioning (Psychology)
KW  - Cues
KW  - Substance Use Disorders
KW  - Drug Tolerance
KW  - Substance Withdrawal Syndrome
SP  - 1113
EP  - 1124 12p
JO  - Addiction
JF  - Addiction
JA  - ADDICTION
VL  - 94
IS  - 8
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Environmental cues associated with drug use become capable of eliciting withdrawal symptoms, craving and relapse to drug self-administration. The phenomenon, although noted almost 150 years ago, has repeatedly been confirmed in epidemiological and experimental studies. Drug tolerance, which is closely correlated with withdrawal symptoms and craving, is also modulated by drug-associated environmental cues. The contribution of predrug cues to withdrawal and tolerance is emphasized in a Pavlovian conditioning analysis of drug administration. Drug-induced disturbances are modulated by homeostatic responses elicited by pharmacological stimulation. According to the conditioning analysis, we learn to anticipate the drug effect; corrective response (conditional compensatory responses) occur in the presence of situations and events that have been associated with the drug in the past. These conditional responses, seen in anticipation of drugs, importantly contribute to drug tolerance, failures of tolerance (enigmatic overdoses), and withdrawal symptoms. I review evidence indicating that a complete analysis of drug withdrawal and tolerance requires an appreciation of the contribution of Pavlovian conditioning.
SN  - 0965-2140
AD  - Department of Psychology, McMaster University, Ontario, Canada. siegel@mcmaster.ca
U2  - PMID: 10615727.
DO  - 10.1046/j.1360-0443.1999.94811132.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104952047
T1  - Drug-drug interactions that reduce the formation of pharmacologically active metabolites: a poorly understood problem in clinical practice.
AU  - Mannheimer B
AU  - Eliasson E
Y1  - 2010/12//
N1  - Accession Number: 104952047. Language: English. Entry Date: 20110128. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 8904841. 
KW  - Biotransformation -- Drug Effects
KW  - Drug Interactions
KW  - Analgesics, Opioid -- Metabolism
KW  - Analgesics, Opioid -- Pharmacodynamics
KW  - Angiotensin II Type I Receptor Blockers -- Metabolism
KW  - Angiotensin II Type I Receptor Blockers -- Pharmacodynamics
KW  - Antineoplastic Agents, Hormonal -- Metabolism
KW  - Antineoplastic Agents, Hormonal -- Pharmacodynamics
KW  - Codeine -- Metabolism
KW  - Codeine -- Pharmacodynamics
KW  - Losartan -- Metabolism
KW  - Losartan -- Pharmacodynamics
KW  - Platelet Aggregation Inhibitors -- Metabolism
KW  - Platelet Aggregation Inhibitors -- Pharmacodynamics
KW  - Tamoxifen -- Metabolism
KW  - Tamoxifen -- Pharmacodynamics
KW  - Ticlopidine
KW  - Ticlopidine -- Metabolism
KW  - Ticlopidine -- Pharmacodynamics
SP  - 540
EP  - 548 9p
JO  - Journal of Internal Medicine
JF  - Journal of Internal Medicine
JA  - J INTERN MED
VL  - 268
IS  - 6
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Abstract. Mannheimer B, Eliasson E (Karolinska Institutet, Stockholm; Karolinska University Hospital Huddinge, Stockholm, Sweden) Drug-drug interactions that reduce the formation of pharmacologically active metabolites: a poorly understood problem in clinical practice (Review-Symposium). J Intern Med 2010; 268: 540-548. Drug-drug interactions can lead to reduced efficacy of medical treatment. Therapeutic failure may for instance result from combined treatment with an inhibitor of the specific pathway that is responsible for the generation of pharmacologically active drug metabolites. This problem may be overlooked in clinical practice. Several examples of drugs will be discussed -clopidogrel, losartan, tamoxifen and codeine - to illustrate differences in the potential impact on drug treatment in clinical practice. We conclude that the combined use of cytochrome P450-blocking serotonin reuptake inhibitors and tamoxifen or codeine should be avoided, whereas the situation is much more complex regarding the use of proton pump inhibitors together with clopidogrel, and the evidence regarding cytochrome P450 inhibitor-dependent activation of losartan is inconclusive.
SN  - 0954-6820
AD  - From the Karolinska Institutet Department of Clinical Science and Education at Södersjukhuset Department of Laboratory Medicine, Division of Clinical Pharmacology at Karolinska University Hospital Huddinge, Stockholm, Sweden.
U2  - PMID: 21091806.
DO  - 10.1111/j.1365-2796.2010.02303.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - THES
ID  - 109876273
T1  - Effect of pain education of postoperative pain management.
AU  - Watkins GR
Y1  - 2001/01//
N1  - Accession Number: 109876273. Language: English. Entry Date: 20030509. Revision Date: 20150923. Publication Type: Doctoral Dissertation; research. 
KW  - Postoperative Pain -- Prevention and Control
KW  - Postoperative Pain -- Education
KW  - Patient Discharge Education
KW  - Orem Self-Care Model
KW  - Conceptual Framework
KW  - Pretest-Posttest Design
KW  - Outpatients
KW  - Two-Way Analysis of Variance
KW  - Repeated Measures
KW  - Interviews
KW  - Experimental Studies
KW  - Health Knowledge
KW  - Ambulatory Surgery
KW  - Human
SP  - 195 p
EP  - 195 p 1p
JO  - Effect of Pain Education of Postoperative Pain Management
JF  - Effect of Pain Education of Postoperative Pain Management
PB  - University of Illinois at Chicago, Health Sciences Center
AB  - This study, guided by Orem's self-care model of nursing, compared the effect of two education interventions on post-discharge knowledge, pain management (use of pain relieving interventions), and pain intensity using a 2-group pretest-posttest study design with random assignment to control or experimental group. The sample included adult surgical outpatients discharged less than 24 hours following an open or laparoscopic abdominal or inguinal outpatient surgical procedure performed under general anesthesia. The control group received only minimal general information related to taking pain medication 'as needed' (routine pain education); the experimental group received specific information about patient-related barriers to pain management and the effective use of both pharmacological and non-pharmacological pain relieving interventions (routine pain education plus booklet). Pretest data collection occurred before surgery; posttest data collection occurred by telephone on postoperative days one, four, and seven.Two-way repeated measures ANOVA were used to evaluate differences between education group, time, and interaction between group and tine. Results were reported for two sets of subjects: the 120 who completed the first two interviews (pretest and postoperative day one) and the 79 who completed all four interviews.At pretest, control and experimental groups were similar on all variables. From pretest to postoperative day one, the experimental group experienced a greater increase in pain management knowledge (total score and addiction subscale) than the control group with the increase in knowledge for both groups remaining stable through postoperative day seven. However, there was no significant difference between control and experimental groups on postoperative days one, four, or seven in the use of pain relieving interventions (pharmacological and non-pharmacological), pain intensity, or pain interference with daily activities.Pain management education facilitated an increase in knowledge, but did not result in an increase in the use of pain relieving interventions. Education alone may be insufficient to change behavior; development of more powerful interventions to facilitate an increase in the use of pain relieving interventions by surgical outpatients are needed. Implications for clinical practice and future research are discussed.
SN  - 9780493456522
AV  - UMI Order AAI3033425
M1  - Ph.D.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109876273&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104528604
T1  - Effective Delivery of Pharmaceutical Palliative Care: Challenges in the Community Pharmacy Setting.
AU  - Akram, Gazala
AU  - Bennie, Marion
AU  - McKellar, Susan
AU  - Michels, Susanna
AU  - Hudson, Stephen
AU  - Trundle, Janet
Y1  - 2012/03//
N1  - Accession Number: 104528604. Language: English. Entry Date: 20120410. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Palliative Care/Hospice. NLM UID: 9808462. 
KW  - Palliative Care
KW  - Pharmacy, Retail
KW  - Professional Role
KW  - Health Care Delivery
KW  - Human
KW  - Qualitative Studies
KW  - Focus Groups
KW  - Interviews
KW  - Scotland
KW  - Pharmacists
KW  - Audiorecording
KW  - Thematic Analysis
KW  - Drugs, Prescription -- Supply and Distribution
KW  - Communication
KW  - Interprofessional Relations
KW  - Multidisciplinary Care Team
SP  - 317
EP  - 321 5p
JO  - Journal of Palliative Medicine
JF  - Journal of Palliative Medicine
JA  - J PALLIAT MED
VL  - 15
IS  - 3
CY  - New Rochelle, New York
PB  - Mary Ann Liebert, Inc.
AB  - Background: Medication, particularly analgesia, is an important component of palliative care. However, timely access to medication, particularly opioids, can become problematic for patients receiving palliative care in the community setting. In Scotland in 2009, NHS Greater Glasgow & Clyde Health Board (NHS GG&C), in partnership with Macmillan Cancer Support, established a programme to improve the local provision of pharmaceutical palliative care services with the appointment of Macmillan Pharmacist Facilitators. Researchers at the University of Strathclyde were commissioned to support the development and evaluation of this new service. We report the findings of this initial investigation into the provision of current palliative care services and outline an evidence-based action plan to support service improvement. Methods and results: Qualitative data were gathered using focus group interviews. Three key themes were identified: medication supply, communication, and education and training. Conclusions: The study findings have been used to develop an evidence-based action plan for the Macmillan Pharmacist Facilitators. This program of work is due for completion by December 2012.
SN  - 1096-6218
AD  - , Glasgow, .
AD  - Retired.
AD  - Undergraduate Erasmus student, , Glasgow, .
AD  - , Glasgow, (deceased).
U2  - PMID: 22339286.
DO  - 10.1089/jpm.2011.0262
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104186025
T1  - Effectiveness of education in health in the nonmedication treatment of arterial hypertension.
AU  - Lopes Oliveira, Thatiane
AU  - de Paula Miranda, Leonardo
AU  - de Sousa Fernandes, Patrícia
AU  - Prates Caldeira, Antônio
Y1  - 2013/03//
N1  - Accession Number: 104186025. Language: English. Entry Date: 20130703. Revision Date: 20150820. Publication Type: Journal Article; research; tables/charts. Journal Subset: Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Mexico & Central/South America; Nursing; Peer Reviewed. Special Interest: Public Health. Instrumentation: International Physical Activity Questionnaire (IPAQ). NLM UID: 9203117. 
KW  - Hypertension -- Therapy
KW  - Patient Education
KW  - Patient Compliance
KW  - Health Behavior
KW  - Life Style Changes
KW  - Family Services
KW  - Brazil
KW  - Behavioral Changes
KW  - Food Habits
KW  - Physical Activity
KW  - Smoking
KW  - Alcoholism
KW  - Blood Pressure
KW  - Body Mass Index
KW  - Waist Circumference
KW  - Outpatients
KW  - Prospective Studies
KW  - Confidence Intervals
KW  - Power Analysis
KW  - Questionnaires
KW  - DASH Diet
KW  - Hypertension -- Diet Therapy
KW  - Hypertension -- Classification
KW  - Chi Square Test
KW  - McNemar's Test
KW  - Data Analysis Software
KW  - Male
KW  - Female
KW  - Adult
KW  - Middle Age
KW  - Aged
KW  - Aged, 80 and Over
KW  - Marital Status
KW  - Educational Status
KW  - Human
KW  - Descriptive Statistics
SP  - 179
EP  - 184 6p
JO  - Acta Paulista de Enfermagem
JF  - Acta Paulista de Enfermagem
JA  - ACTA PAUL ENFERMAGEM
VL  - 26
IS  - 2
PB  - Universidade Federal de Sao Paulo, Escola Paulista de Enfermagem
AB  - Objective: To verify the efficacy of health education on the adherence to non-pharmacological treatment inarterial hypertension. Methods: Habits related to nutrition, physical activity and use of tobacco and alcohol were analyzed, as well as assessment of anthropometric and blood pressure levels, before and after the performance of group health education in 216 hypertensive patients. Results: There was a statistically significant change in the consumption of legumes, in the adherence to physical activity, in the reduction of body mass index and abdominal circumference, and in the control of arterial pressure, after the health education groups. Conclusion: The proposed health education was effective in incentivizing the adherence to non-pharmacological treatment in arterial hypertension, evidenced by the relevance of the adoption of these educational strategies for health professionals.
SN  - 0103-2100
AD  - Universidade Estadual de Montes Claros, Montes Carlos, MG, Brazil
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 113551971
T1  - Effectiveness of the clinical pharmacist in reducing mortality in hospitalized cardiac patients: a propensity score-matched analysis.
AU  - Xiao-bo Zhai
AU  - Zhi-chun Gu
AU  - Xiao-yan Liu
AU  - Zhai, Xiao-Bo
AU  - Gu, Zhi-Chun
AU  - Liu, Xiao-Yan
Y1  - 2016/02//
N1  - Accession Number: 113551971. Language: English. Entry Date: In Process. Revision Date: 20160315. Publication Type: journal article. Journal Subset: Europe; Health Services Administration; UK & Ireland. NLM UID: 101253281. 
SP  - 241
EP  - 250 10p
JO  - Therapeutics & Clinical Risk Management
JF  - Therapeutics & Clinical Risk Management
JA  - THER CLIN RISK MANAGE
VL  - 12
CY  - Auckland, <Blank>
PB  - Dove Medical Press Ltd
AB  - Background: Pharmacist-led medication review services have been assessed in the meta-analyses in hospital. Of the 135 relevant articles located, 21 studies met the inclusion criteria; however, there was no statistically significant difference found between pharmacists' interventions and usual care for mortality (odds ratio 1.50, 95% confidence interval 0.65, 3.46, P=0.34). These analyses may not have found a statistically significant effect because they did not adequately control the wide variation in the delivery of care and patient selection parameters. Additionally, the investigators did not conduct research on the cases of death specifically and did not identify all possible drug-related problems (DRPs) that could cause or contribute to mortality and then convince physicians to correct. So there will be a condition to use a more precise approach to evaluate the effect of clinical pharmacist interventions on the mortality rates of hospitalized cardiac patients. Objective: To evaluate the impact of the clinical pharmacist as a direct patient-care team member on the mortality of all patients admitted to the cardiology unit. Methods: A comparative study was conducted in a cardiology unit of a university-affiliated hospital. The clinical pharmacists did not perform any intervention associated with improper use of medications during Phase I (preintervention) and consulted with the physicians to address the DRPs during Phase II (postintervention). The two phases were compared to evaluate the outcome, and propensity score (PS) matching was applied to enhance the comparability. The primary endpoint of the study was the composite of all-cause mortality during Phase I and Phase II. Results: Pharmacists were consulted by the physicians to correct any drug-related issues that they suspected may cause or contribute to a fatal outcome in the cardiology ward. A total of 1,541 interventions were suggested by the clinical pharmacist in the study group; 1,416 (92.0%) of them were accepted by the cardiology team, and violation of incompatibilities had the highest percentage of acceptance by the cardiology team. All-cause mortality was 1.5% during Phase I (preintervention) and was reduced to 0.9% during Phase II (postintervention), and the difference was statistically significant (P=0.0005). After PS matching, all-cause mortality changed from 1.7% during Phase I down to 1.0% during Phase II, and the difference was also statistically significant (P=0.0074). Conclusion: DRPs that were suspected to cause or contribute to a possibly fatal outcome were determined by clinical pharmacist service in patients hospitalized in a cardiology ward. Correction of these DRPs by physicians after pharmacist's advice caused a significant decrease in mortality as analyzed by PS matching. The significant reduction in the mortality rate in this patient population observed in this study is "hypothesis generating" for future randomized studies.
SN  - 1176-6336
AD  - Department of Pharmacy, Shanghai East Hospital, Affiliated to Tongji University School of Medicine
AD  - Department of Pharmacy, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China
AD  - Department of Pharmacy, Shanghai East Hospital, Affiliated to Tongji University School of Medicine, Shanghai, People's Republic of China
U2  - PMID: 26937196.
DO  - 10.2147/TCRM.S98300
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106473663
T1  - Effects on sick leave of an inpatient rehabilitation programme for asthmatics in a randomized trial.
AU  - Nathell L
Y1  - 2005/01//
N1  - Accession Number: 106473663. Language: English. Entry Date: 20050624. Revision Date: 20150711. Publication Type: Journal Article; clinical trial; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; Public Health; UK & Ireland. Grant Information: Funded by the research department of AFA, Stockholm, Sweden. NLM UID: 100883503. 
KW  - Asthma -- Rehabilitation
KW  - Hospital Programs -- Evaluation
KW  - Rehabilitation -- Methods
KW  - Sick Leave -- Utilization
KW  - Asthma -- Diagnosis
KW  - Asthma -- Drug Therapy
KW  - Chi Square Test
KW  - Clinical Trials
KW  - Coping
KW  - Data Analysis Software
KW  - Descriptive Statistics
KW  - Evaluation Research
KW  - Female
KW  - Funding Source
KW  - Inpatients
KW  - Male
KW  - Mann-Whitney U Test
KW  - McNemar's Test
KW  - Patient Education
KW  - Physical Therapy
KW  - Program Evaluation
KW  - Prospective Studies
KW  - Questionnaires
KW  - Random Sample
KW  - Rehabilitation Centers
KW  - Smoking Cessation
KW  - Smoking -- Complications
KW  - Statistical Significance
KW  - Structured Interview
KW  - Two-Tailed Test
KW  - Human
SP  - 57
EP  - 64 8p
JO  - Scandinavian Journal of Public Health
JF  - Scandinavian Journal of Public Health
JA  - SCAND J PUBLIC HEALTH
VL  - 33
IS  - 1
PB  - Sage Publications, Ltd.
AB  - AIM: Among adult asthmatics a major proportion of the cost of illness is attributed to productivity losses and societal costs in connection with sick leave compensation. The aim of the study was to evaluate an extensive structured four-week inpatient rehabilitation programme for asthmatics. METHODS: A diagnosis of asthma was made in a structured way among people on sick leave due to a respiratory disorder. In total, 197 persons were randomized to either a rehabilitation programme, or to usual care. The main components of the rehabilitation programme were education, pharmacological optimization, physical training, and coping skill acquisition. RESULTS: At the three-year follow-up, the median number of sick leave days in the rehabilitation group was 104, and in the usual care group 167 (p = 0.12). An analysis of a subgroup consisting of persons not currently smoking with a previous diagnosis of asthma by a physician (n = 57) showed a significant effect on sick leave at three years (median number of days 63 in the rehabilitation group vs 361 in the control group, p = 0.02). All analyses were based on intention to treat. CONCLUSIONS: The long-term effects on sick leave of an extensive inpatient asthma rehabilitation programme are most evident for non-smokers and ex-smokers with a previous asthma diagnosis. It is therefore recommended that persons with asthma who are current smokers should be offered participation in smoking cessation programmes instead of asthma rehabilitation programmes.
SN  - 1403-4948
AD  - Section of Personal Injury Prevention, Department of Clinical Neuroscience, Karolinska Institutet, P.O. Box 12718, SE-112 94 Stockholm, Sweden; lennart.nathell@home.se
U2  - PMID: 15764242.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104436758
T1  - Epidemiology and potential associated risk factors of drug-related problems in hospitalised children in the United Kingdom and Saudi Arabia.
AU  - Rashed, Asia
AU  - Neubert, Antje
AU  - Tomlin, Stephen
AU  - Jackman, John
AU  - Alhamdan, Hani
AU  - AlShaikh, Adnan
AU  - Attar, Ahmed
AU  - Aseeri, Mohammed
AU  - Wilton, Lynda
AU  - Wong, Ian
Y1  - 2012/12//
N1  - Accession Number: 104436758. Language: English. Entry Date: 20121120. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. Grant Information: The study in the UK was funded by the Neonatal and Paediatric Pharmacists Group (NPPG) Man-Med award 2009.. NLM UID: 1256165. 
KW  - Adverse Drug Event -- Epidemiology -- United Kingdom
KW  - Adverse Drug Event -- Epidemiology -- Saudi Arabia
KW  - Adverse Drug Event -- Risk Factors
KW  - Child, Hospitalized
KW  - Adolescent, Hospitalized
KW  - United Kingdom
KW  - Saudi Arabia
KW  - Prospective Studies
KW  - Child, Preschool
KW  - Child
KW  - Infant
KW  - Adolescence
KW  - Infant, Newborn
KW  - Male
KW  - Female
KW  - Incidence
KW  - Confidence Intervals
KW  - Academic Medical Centers
KW  - Nonexperimental Studies
KW  - Multicenter Studies
KW  - Record Review
KW  - Data Analysis Software
KW  - Adverse Drug Event -- Classification
KW  - Kruskal-Wallis Test
KW  - Wilcoxon Rank Sum Test
KW  - Mann-Whitney U Test
KW  - Odds Ratio
KW  - Funding Source
SP  - 1657
EP  - 1666 10p
JO  - European Journal of Clinical Pharmacology
JF  - European Journal of Clinical Pharmacology
JA  - EUR J CLIN PHARMACOL
VL  - 68
IS  - 12
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
AB  - Aim: Drug-related problems (DRP) are 'an event or circumstance involving drug therapy that actually or potentially interferes with the desired health outcome'. The extent and characteristics of DRPs in children in the UK and the Kingdom of Saudi Arabia (KSA) are unknown. Our aim was to determine the epidemiology of and identify risk factors for DRPs in hospitalised children. Methods: A prospective cohort study was carried out in children aged 0-18 years, admitted to the medical ward, paediatric intensive care unit (PICU) and neonatal intensive care unit (NICU) during a 3-month period in two hospitals. Patients' charts, medical records and laboratory data were reviewed daily to identify DRPs; their preventability and severity were assessed. Logistic regression was used to analyse the potential risk factors associated with DRP incidence. Results: Seven hundred and thirty-seven children (median age 2.3 years, interquartile range 6 months to 8 years, 58.1% male) were included. Three hundred and thirty-three patients suffered from 478 DRPs. Overall DRP incidence was 45.2% (95% CI, 41.5-48.8); KSA (51.1%; 95% CI, 45.8-56.3), UK (39.4%; 95% CI, 34.4-44.6). Incidence was highest in the PICU (59.7%; 95% CI, 47.0-71.5). Dosing problems were the most frequently reported DRPs ( n = 258, 54%). 80.3% of DRP ( n = 384) cases were preventable; 72.2% ( n = 345) of DRPs were assessed as minor; 27% ( n = 129) as moderate. Number of prescriptions and type of admission (transferred) were potential risk factors for DRP occurrence in children. Conclusions: Drug-related problems were common in the hospitalised children in this study; the most frequent were dosing problems and drug choice problems; the majority of them were preventable. Polypharmacy and transferred admission (another hospital or ward) were potential risk factors. To improve prescribing practices and minimise the risk of DRPs in hospitalised children, paediatric pharmacology and pharmacotherapy are important in medical education.
SN  - 0031-6970
AD  - Centre for Paediatric Pharmacy Research, UCL School of Pharmacy, 29-39 Brunswick Square London WC1N 1AX UK
AD  - Evelina Children's Hospital, Guy's & St. Thomas' NHS Foundation Trust, London SE1 7EH UK
AD  - National Guard Health Affairs, Kind Abdul-Aziz Medical City-Jeddah, Jeddah 21432 Saudi Arabia
U2  - PMID: 22644343.
DO  - 10.1007/s00228-012-1302-x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106165990
T1  - Ethical and practical issues with opioids in life-limiting illness.
AU  - Fine RL
Y1  - 2007/01//
N1  - Accession Number: 106165990. Language: English. Entry Date: 20071005. Revision Date: 20150711. Publication Type: Journal Article; case study; pictorial; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Pain and Pain Management; Palliative Care/Hospice. NLM UID: 9302033. 
KW  - Narcotics -- Pharmacodynamics
KW  - Narcotics -- Therapeutic Use
KW  - Pain -- Drug Therapy
KW  - Substance Dependence
KW  - Terminal Care
KW  - Terminally Ill Patients
KW  - Aged
KW  - Female
SP  - 5
EP  - 12 8p
JO  - Baylor University Medical Center Proceedings
JF  - Baylor University Medical Center Proceedings
JA  - BAYLOR UNIV MED CENT PROC
VL  - 20
IS  - 1
CY  - Dallas, Texas
PB  - Baylor University Medical Center
AB  - Effective pain relief, especially at the end of life, is a primary ethical obligation based upon the principles of beneficence, nonmaleficence, patient autonomy, and particularly the concept of double effect. The pragmatic foundation of pain management begins with a complete assessment, which incorporates 'WILDA' (words, intensity, location, duration, aggravating/alleviating factors) and considers the components of total pain: physical, emotional, social, and spiritual pain. Opioids are the pharmacologic sine qua non of pain management in life-limiting illness and should be prescribed based on the severity of pain, considering the functional and psychological significance of that severity. Numerous misunderstandings present a barrier to effective pain management. These misconceptions include the idea that opioids are highly addictive, that dependence or tolerance are forms of addiction, that respiratory depression is common with opioids, that opioids have a narrow therapeutic range, and that opioids are ineffective by mouth and cause too much nausea. In reality, opioids are the safest and most effective pain medicine for most moderate to severe pain in most patients. Aspects of basic opioid pharmacology, such as dosage, route of administration, rotation of drugs, and the avoidance of toxicity and complications, should be considered when initiating and maintaining therapy. Failure to pay attention to the basic rules can lead to errors in opioid management.
SN  - 0899-8280
AD  - Office of Clinical Ethics, Baylor Health Care System, and Palliative Care Consultation Service, Baylor University Medical Center, Dallas, Texas.
U2  - PMID: 17256034.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104381163
T1  - Evaluation of online training for the provision of opioid substitution treatment by community pharmacists in New Zealand.
AU  - Walters C
AU  - Raymont A
AU  - Galea S
AU  - Wheeler A
Y1  - 2012/11//
N1  - Accession Number: 104381163. Language: English. Entry Date: 20130517. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9015440. 
KW  - Education, Pharmacy
KW  - Pharmacists -- Administration
KW  - Pharmacy, Retail -- Administration
KW  - Substance Use Disorders -- Drug Therapy
KW  - Adult
KW  - Attitude of Health Personnel
KW  - Attitude to Health
KW  - Clinical Competence
KW  - Female
KW  - Human
KW  - Internet
KW  - Male
KW  - Middle Age
KW  - New Zealand
KW  - Pharmacists -- Standards
KW  - Pharmacy, Retail -- Standards
KW  - Pilot Studies
KW  - Questionnaires
KW  - Substance Use Disorders -- Rehabilitation
KW  - Young Adult
SP  - 903
EP  - 910 8p
JO  - Drug & Alcohol Review
JF  - Drug & Alcohol Review
JA  - DRUG ALCOHOL REV
VL  - 31
IS  - 7
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 0959-5236
AD  - Community Alcohol and Drug Services (CADS), Waitemata District Health Board, Auckland, New Zealand Clinical Research and Resource Centre, Waitemata District Health Board, Auckland, New Zealand Griffith Health Institute, Griffith University, Brisbane, Australia Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
U2  - PMID: 22519647.
DO  - 10.1111/j.1465-3362.2012.00459.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109989621
T1  - Evaluation of outpatient medication reconciliation involving student pharmacists at a comprehensive cancer center.
AU  - Ashjian, Emily
AU  - Salamin, Louise B.
AU  - Eschenburg, Katie
AU  - Kraft, Shawna
AU  - Mackler, Emily
Y1  - 2015/09//Sep/Oct2015
N1  - Accession Number: 109989621. Language: English. Entry Date: 20160406. Revision Date: 20160406. Publication Type: journal article. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Learning and Study Strategies Inventory (LASSI). NLM UID: 101176252. 
KW  - Ambulatory Care
KW  - Medication Reconciliation
KW  - Patient Satisfaction
KW  - Students, Pharmacy
KW  - Cancer Care Facilities -- Manpower
KW  - Neoplasms -- Drug Therapy
KW  - Middle Age
KW  - Female
KW  - Male
KW  - Program Evaluation
KW  - Health Services Needs and Demand
KW  - Michigan
SP  - 540
EP  - 545 6p
JO  - Journal of the American Pharmacists Association: JAPhA
JF  - Journal of the American Pharmacists Association: JAPhA
JA  - J AM PHARM ASSOC
VL  - 55
IS  - 5
CY  - Washington, District of Columbia
PB  - American Pharmacists Association
AB  - Objective: To determine the number of discrepancies and medication-related problems found as a result of pharmacy-led medication reconciliation involving introductory pharmacy practice experience (IPPE) students at a comprehensive cancer center.Setting: Outpatient infusion center of a National Cancer Institute (NCI)-designated and National Comprehensive Cancer Network (NCCN) cancer center.Practice Description and Innovation: Third-year IPPE students contacted and completed medication reconciliation for 510 hematology/oncology patients scheduled for infusion center appointments without a coupled provider visit. IPPE students discussed the findings of the medication reconciliations with their pharmacist preceptors, who updated the medication histories in the electronic medical record (EMR) and communicated with prescribers directly about identified medication-related problems. All medication reconciliation was documented using a standardized note template in the EMR.Main Outcome Measures: Number of medication discrepancies found, including medication additions, medication deletions, dose changes, and herbal product additions; medication-related problems-including drug-drug interactions, untreated indications (e.g., nausea, vomiting, pain, need for prophylactic medications), failure of patients to receive prescribed medications, and adverse drug reactions-were also documented.Results: Medication reconciliation was completed for 510 patients through the student pharmacist/pharmacist preceptor-led intervention during a 1-year period between January 1, 2013, and December 31, 2013. A total of 88% of patients had at least one discrepancy identified in their medication history and corrected in the EMR. In addition, 11.4% of patients had a medication-related problem identified.Conclusions: Pharmacy-led medication reconciliation identified a large number of discrepancies among our hematology/oncology patients. This intervention allowed for correction of discrepancies in the EMR leading to improved accuracy of patient medication lists. In addition, it provided a valuable learning experience for student pharmacists.
SN  - 1544-3191
AD  - Clinical Assistant Professor, Department of Pharmacy Practice, Oregon State University/ Oregon Health & Science University College of Pharmacy, Portland, OR
AD  - Clinical Nurse Manager (Retired), University of Michigan Comprehensive Cancer Center, Ann Arbor, Ml
AD  - Pharmacist Generalist, Cancer Center Infusion, Department of Pharmacy Services, University of Michigan Health System, Ann Arbor, Ml
AD  - Clinical Assistant Professor, University of Michigan Comprehensive Cancer Center, Ann Arbor, Ml
AD  - Oncology Clinical Pharmacist, Michigan Oncology Quality Consortium, University of Michigan Comprehensive Cancer Center, Ann Arbor, Ml
U2  - PMID: 26359964.
DO  - 10.1331/JAPhA.2015.14214
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108105435
T1  - Evolution in Pharmacy Education: Developing Effective Patient Care Practitioners.
AU  - Chernushkin, Kseniya
AU  - Loewen, Peter
AU  - de Lemos, Jane
AU  - Aulakh, Amneet
AU  - Jung, Joanne
AU  - Dahri, Karen
Y1  - 2012/07//2012 Jul-Aug
N1  - Accession Number: 108105435. Language: English. Entry Date: 20121214. Revision Date: 20150712. Publication Type: Journal Article; editorial. Journal Subset: Biomedical; Canada. NLM UID: 0215645. 
KW  - Pharmacy and Pharmacology
KW  - Medical Practice
KW  - Pharmacists
KW  - Serial Publications
SP  - 258
EP  - 264 7p
JO  - Canadian Journal of Hospital Pharmacy
JF  - Canadian Journal of Hospital Pharmacy
JA  - CAN J HOSP PHARM
VL  - 65
IS  - 4
CY  - Milton, Ontario
PB  - Multimed Inc.
AB  - Background: Hospital pharmacists participate in activities that may be considered diagnostic. Two reasoning approaches to diagnosis have been described: non-analytic and analytic. Of the 6 analytic traditions, the probabilistic tradition has been shown to improve diagnostic accuracy and reduce unnecessary testing. To the authors' knowledge, pharmacists' attitudes toward having a diagnostic role and their diagnostic knowledge and skills have never been studied. Objectives: To describe pharmacists' attitudes toward the role of diagnosis in pharmacotherapeutic problem-solving and to characterize the extent of pharmacists' knowledge and skills related to diagnostic literacy. Methods: Pharmacists working within Lower Mainland Pharmacy Services (British Columbia) who spent at least 33% of their time in direct patient care were invited to participate in a prospective observational survey. The survey sought information about demographic characteristics and attitudes toward diagnosis. Diagnostic knowledge and skills were tested by means of 3 case scenarios. The analysis included simple descriptive statistics and inferential statistics to evaluate relationships between responses and experience and training. Results: Of 266 pharmacists invited to participate, 94 responded. The attitudes section of the survey was completed by 90 pharmacists; of these, 80 (89%) agreed with the definition of 'diagnosis' proposed in the survey, and 83 (92%) agreed that it is important for pharmacists to have diagnosis-related skills. Respondents preferred an analytic to a nonanalytic approach to diagnostic decision-making. The probabilistic tradition was not the preferred method in any of the 3 cases. In evaluating 5 clinical scenarios that might require diagnostic skills, on average 84% of respondents agreed that they should be involved in assessing such problems. Respondents' knowledge of and ability to apply probabilistic diagnostic tools were highest for test sensitivity (average of 61% of respondents with the correct answers) and lower for test specificity (average of 48% with correct answers) and likelihood ratios (average of 39% with correct answers). Conclusions: Respondents to this survey strongly believed that diagnostic skills were important for solving drug related problems, but they demonstrated low levels of knowledge and ability to apply concepts of probabilistic diagnostic reasoning. Opportunities to expand pharmacists' knowledge of diagnostic reasoning exist, and the findings reported here indicate that pharmacists would consider such professional development valuable.
SN  - 0008-4123
U2  - PMID: 22919101.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108105435&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105531873
T1  - Expanding access to sterile syringes through pharmacies: Assessment of New York's Expanded Syringe Access Program.
AU  - Tesoriero JM
AU  - Battles HB
AU  - Klein SJ
AU  - Kaufman E
AU  - Birkhead GS
Y1  - 2009/05//May/Jun2009
N1  - Accession Number: 105531873. Language: English. Entry Date: 20090724. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 101176252. 
KW  - Health Services Accessibility -- Administration
KW  - Needle Exchange Programs -- Administration
KW  - Pharmacists -- Administration
KW  - Pharmacy Service -- Administration
KW  - Attitude of Health Personnel
KW  - Data Collection
KW  - Education, Pharmacy
KW  - Harm Reduction
KW  - New York
KW  - Prospective Studies
KW  - Refuse Disposal
KW  - Substance Abuse, Intravenous -- Complications
KW  - Syringes -- Supply and Distribution
KW  - Time Factors
KW  - Human
SP  - 407
EP  - 416 10p
JO  - Journal of the American Pharmacists Association: JAPhA
JF  - Journal of the American Pharmacists Association: JAPhA
JA  - J AM PHARM ASSOC
VL  - 49
IS  - 3
CY  - Washington, District of Columbia
PB  - American Pharmacists Association
SN  - 1544-3191
AD  - New York State Department of Health, AIDS Institute, Menands, NY.
U2  - PMID: 19443321.
DO  - 10.1331/JAPhA.2009.07127
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105531873&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104485155
T1  - Experience With a Drug Screening Program at a School of Pharmacy.
AU  - Cates, Marshall E.
AU  - Hogue, Michael D.
Y1  - 2012/08//Aug/Sep2012
N1  - Accession Number: 104485155. Language: English. Entry Date: 20120822. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 7503059. 
KW  - Substance Abuse Detection
KW  - Students, Pharmacy
KW  - Program Implementation
KW  - Student Placement
KW  - Pharmacy, Retail
KW  - Mandatory Reporting
KW  - Contracts
KW  - Urinalysis
KW  - Student Discipline
KW  - Clinical Laboratories
KW  - School Policies
SP  - 476
EP  - 480 5p
JO  - Journal of American College Health
JF  - Journal of American College Health
JA  - J AM COLL HEALTH
VL  - 60
IS  - 6
PB  - Taylor & Francis Ltd
AB  - Substance use and abuse among pharmacy students is a concern of pharmacy schools, boards of pharmacy, and training sites alike. Pharmacy students must complete approximately 30% of their academic coursework in experiential settings such as community pharmacies, hospitals, and other health systems as part of any accredited pharmacy school's curriculum, and these training sites are starting to require drug testing of pharmacy students as part of their contractual agreements with schools of pharmacy. The authors describe the implementation of a mandatory random urine drug screening program at their school as well as the changes that occurred owing to assessment of the program. The authors report the basic results to date of the drug screening program. The authors also speculate on secondary benefits of the drug screening program. Finally, the authors describe current and future evaluations that they are undertaking regarding this program.
SN  - 0744-8481
AD  - Department of Pharmacy Practice, McWhorter School of Pharmacy, Samford University, Birmingham, Alabama
U2  - PMID: 22857140.
DO  - 10.1080/07448481.2012.688780
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104485155&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109716733
T1  - Factors associated with provision of addiction treatment information by community pharmacists.
AU  - Hagemeier, Nicholas E
AU  - Alamian, Arsham
AU  - Murawski, Matthew M
AU  - Pack, Robert P
Y1  - 2015/05//
N1  - Accession Number: 109716733. Language: English. Entry Date: 20150923. Revision Date: 20151223. Publication Type: journal article. Journal Subset: Biomedical; USA. NLM UID: 8500909. 
SP  - 67
EP  - 72 6p
JO  - Journal of Substance Abuse Treatment
JF  - Journal of Substance Abuse Treatment
JA  - J SUBST ABUSE TREAT
VL  - 52
PB  - Pergamon Press - An Imprint of Elsevier Science
AB  - Community pharmacists in the United States have significant opportunity to engage in community-level prescription substance abuse prevention and treatment efforts, including dissemination of information specific to available addiction treatment options. Our cross-sectional study of Tennessee community pharmacists noted that 26% had previously provided addiction treatment facility information to one or more patients in the past. The purpose of this study was to employ multivariate modeling techniques to investigate associations between community pharmacist and community pharmacy factors and past provision of addiction treatment information to pharmacy patients. Multivariate logistic regression indicated having addiction treatment facility information in a pharmacy setting (aOR=8.19; 95% CI=4.36-15.37), having high confidence in ability to discuss treatment facility options (aOR=4.16; 95% CI=2.65-6.52), having participated in prescription opioid abuse-specific continuing education (aOR=2.90; 95% CI=1.70-4.97), being male (aOR=2.23; 95% CI=1.38-3.59), and increased hours per week in the practice setting (aOR=1.02; 95% CI=1.004-1.05) were all significantly associated with provision of information about addiction treatment. Dissemination of addiction treatment information, improvements in communicative self-efficacy beliefs, and dissemination of prescription opioid abuse-specific continuing education are modifiable factors significantly associated with increased provision of addiction treatment information by community pharmacists.
SN  - 0740-5472
U2  - PMID: 25491734.
DO  - 10.1016/j.jsat.2014.11.006
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109716733&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104143482
T1  - Factors responsible for noncompliance to drug therapy in the elderly and the impact of patient education on improving compliance.
AU  - Shah, Rima
AU  - Desai, Sagun
AU  - Gajjar, Bharat
AU  - Shah, Amit
Y1  - 2013/11//
N1  - Accession Number: 104143482. Language: English. Entry Date: 20131023. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Gerontologic Care. NLM UID: 9308798. 
KW  - Medication Compliance -- Education -- In Old Age
KW  - Patient Education
KW  - Human
KW  - India
KW  - Random Sample
KW  - Descriptive Statistics
KW  - Polypharmacy
KW  - Socioeconomic Factors
KW  - Prospective Studies
KW  - Confidence Intervals
KW  - Aged
KW  - Questionnaires
KW  - Interviews
KW  - Chi Square Test
KW  - Data Analysis Software
KW  - Aged, 80 and Over
KW  - Male
KW  - Female
SP  - 360
EP  - 366 7p
JO  - Drugs & Therapy Perspectives
JF  - Drugs & Therapy Perspectives
JA  - DRUGS THER PERSPECT
VL  - 29
IS  - 11
PB  - Springer Science & Business Media B.V.
AB  - Background: Noncompliance to drug therapy, a common problem in geriatric patients, adversely affects disease outcomes. In India, data addressing noncompliance in elderly patients, the factors responsible for it and possible solutions for the problem are very limited. Objective: To evaluate the prevalence of drug noncompliance among Indian geriatric patients, explore factors affecting it and examine the impact of educating patients about importance of adhering to drug therapy. Study design: A total of 200 geriatric patients from various outpatient departments were randomly recruited. Baseline information related to diseases and drug therapy were recorded using a structured case-record form that included a questionnaire for evaluation of drug compliance. Patients were randomly divided in two groups of 100 individuals; the interventional group received education about the importance of drug compliance and related issues, and the control group did not. Changes in compliance were evaluated at a follow-up visit 7-14 days later. Results: Noncompliance to drug therapy was reported in 77.5 % of patients, and was significantly associated with socioeconomic status, prescription-related factors (number of medicines prescribed, purchasing drugs from same pharmacy, patients' particularity in taking medicines on time, instructions given by doctors); and drug-related factors (frequency and duration of administration, skewed instructions for use, physical difficulties in taking drugs, price of drug as perceived by patient, cost of therapy, risk of adverse drug reactions as perceived by patient). At follow-up, compliance had significantly improved in the group who had received education relative to the group who did not. Conclusion: Educating geriatric patients about their disease and drug therapy, and the importance of compliance to therapy may improve their short-term compliance behaviour.
SN  - 1172-0360
AD  - Department of Pharmacology, GMERS Medical College, Gandhinagar India
AD  - Department of Pharmacology, SBKS Medical Institute and Research Centre, Piparia Vadodara India
AD  - Department of Pharmacology, Pramukh Swami Medical College, Karamsad India
DO  - 10.1007/s40267-013-0075-3
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104143482&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104099910
T1  - First insights into community pharmacy based buprenorphine-naloxone dispensing in Finland.
AU  - Uosukainen, Hanna
AU  - Bell, J Simon
AU  - Laitinen, Kirsti
AU  - Tacke, Ulrich
AU  - Ilomäki, Jenni
AU  - Turunen, Juha H O
Y1  - 2013/09//
N1  - Accession Number: 104099910. Language: English. Entry Date: 20140516. Revision Date: 20150710. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9014759. 
KW  - Attitude of Health Personnel
KW  - Pharmacy, Retail -- Administration
KW  - Substance Dependence -- Drug Therapy
KW  - Buprenorphine -- Therapeutic Use
KW  - Finland
KW  - Human
KW  - Naloxone -- Therapeutic Use
KW  - Substance Use Disorders -- Drug Therapy
SP  - 492
EP  - 497 6p
JO  - International Journal of Drug Policy
JF  - International Journal of Drug Policy
JA  - INT J DRUG POLICY
VL  - 24
IS  - 5
CY  - New York, New York
PB  - Elsevier Science
AB  - BACKGROUND: Finnish community pharmacies have been permitted to dispense buprenorphine-naloxone since February 2008. This study explored the dispensing practices, service experiences, problems encountered and opportunities for future development. METHODS: In August 2011, a questionnaire was mailed to all Finnish community pharmacies dispensing buprenorphine-naloxone (n=69). RESULTS: Sixty-four pharmacies responded (93%), of which 54 had dispensed buprenorphine-naloxone to 155 clients since 2008. Forty-eight pharmacies had 108 current clients (10% of all buprenorphine-naloxone clients in Finland). Overall satisfaction with buprenorphine-naloxone dispensing was high, with all respondents indicating dispensing had gone 'well' or 'very well'. Fourteen pharmacies (26%) had experienced one or more problems, predominately in relation timing or non-collection of doses. Problems were more common in pharmacies with more than one buprenorphine-naloxone client (odds ratio 1.39, 95% confidence interval 1.05-1.86). Most pharmacies (n=43, 80%) identified opportunities for improvement, including the need for more education and financial remuneration. Forty-six pharmacies (85%) were willing to dispense buprenorphine-naloxone to more clients; however, 43 pharmacies (80%) perceived that supervision of buprenorphine-naloxone dosing is not a suitable task for pharmacists in Finland. CONCLUSION: Provision of buprenorphine-naloxone in Finnish community pharmacies has remained relatively small-scale. As experiences have been generally positive and problems rare, it may be possible to expand these services.
SN  - 0955-3959
AD  - School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland. Electronic address: hanna.uosukainen@uef.fi.
U2  - PMID: 23567099.
DO  - 10.1016/j.drugpo.2013.02.004
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104099910&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105893875
T1  - From the literature.
Y1  - 2006/07//2006 Jul-Aug
N1  - Accession Number: 105893875. Language: English. Entry Date: 20080425. Revision Date: 20150711. Publication Type: Journal Article; abstract. Journal Subset: Biomedical; Blind Peer Reviewed; Double Blind Peer Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Public Health. NLM UID: 8504643. 
KW  - Pharmacy and Pharmacology -- Education
KW  - Influenza -- Prevention and Control
KW  - Smoking -- Drug Therapy
SP  - 234
EP  - 235 2p
JO  - Journal of Pharmacy Technology
JF  - Journal of Pharmacy Technology
JA  - J PHARM TECHNOL
VL  - 22
IS  - 4
CY  - Thousand Oaks, California
PB  - Sage Publications Inc.
SN  - 8755-1225
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105893875&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105554505
T1  - Gender bias in medical textbooks: examples from coronary heart disease, depression, alcohol abuse and pharmacology.
AU  - Dijkstra AF
AU  - Verdonk P
AU  - Lagro-Janssen ALM
Y1  - 2008/10//
N1  - Accession Number: 105554505. Language: English. Entry Date: 20090410. Revision Date: 20150711. Publication Type: Journal Article; research; systematic review; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice. Grant Information: Netherlands Organisation for Health Research and Development (ZonMW). NLM UID: 7605655. 
KW  - Education, Medical -- Evaluation
KW  - Sexism
KW  - Textbooks -- Evaluation
KW  - Alcohol Abuse
KW  - Cardiovascular Diseases
KW  - Depression
KW  - Female
KW  - Funding Source
KW  - Male
KW  - Netherlands
KW  - Pharmacy and Pharmacology
KW  - Human
SP  - 1021
EP  - 1028 8p
JO  - Medical Education
JF  - Medical Education
JA  - MED EDUC
VL  - 42
IS  - 10
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - OBJECTIVES This study aimed to review the availability and accessibility of gender-specific knowledge in current medical textbooks used in Dutch medical schools. Medicine has been criticised as being gender- biased by assuming male and female bodies to be generally the same. The authors wondered whether current nationally and internationally accepted medical textbooks reflect the state of the art on gender-specific knowledge. METHODS The authors selected medical textbooks recommended by at least two medical schools in the Netherlands in the academic years 2004DS05 and 2005-06. Investigated disciplines were internal medicine /cardiology, psychiatry and pharmacology. The textbooks were screened on the following topics: coronary heart disease; depressive disorders; alcohol abuse, and pharmacology. We defined evidencebased, gender-specific aspects of each of the topics on which information should be accessible in current textbooks for medical students. RESULTS Eleven textbooks were screened, including four on internal medicine/cardiology, four on pharmacology and three on psychiatry. Results show that gender-specific information is scarce or absent, and hardly accessible via index or layout. The scarce gender-specific information mainly applies to epidemiological data and reproductive items. CONCLUSIONS Current medical textbooks are still gender-biased. They lack somatic and psychosocial information relevant to good medical practice. As a consequence, future doctors will be unaware of relevant differences between men and women in the presentation, diagnosis and treatment of illnesses.
SN  - 0308-0110
AD  - Department of Family Medicine/Women's Studies in Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
U2  - PMID: 18761614.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105554505&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106326199
T1  - Generic medicines: perceptions of community pharmacists in Melbourne, Australia.
AU  - Hassali MA
AU  - Kong DCM
AU  - Stewart K
Y1  - 2005/09//
N1  - Accession Number: 106326199. Language: English. Entry Date: 20060901. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 101137601. 
KW  - Drugs, Generic
KW  - Pharmacist Attitudes
KW  - Adult
KW  - Aged
KW  - Audiorecording
KW  - Content Analysis
KW  - Convenience Sample
KW  - Data Analysis Software
KW  - Decision Making, Clinical
KW  - Drug Labeling
KW  - Female
KW  - Interview Guides
KW  - Male
KW  - Middle Age
KW  - Patient Education
KW  - Patient Safety
KW  - Qualitative Studies
KW  - Semi-Structured Interview
KW  - Thematic Analysis
KW  - Victoria
KW  - Human
SP  - 27
EP  - 45 19p
JO  - Journal of Pharmaceutical Finance, Economics & Policy
JF  - Journal of Pharmaceutical Finance, Economics & Policy
JA  - J PHARMACEUTICAL FINANC ECON POLICY
VL  - 14
IS  - 3
PB  - Taylor & Francis Ltd
AB  - Objective: The objective of this study was to investigate generic medicine dispensing trends and substitution practices from the perspective of community pharmacists in Melbourne, Australia. Method: A qualitative approach was used. A convenience sample of community pharmacists practicing in Melbourne were interviewed using a semi-structured interview guide. Key Findings: A total of 11 pharmacists were interviewed. Thematic content analysis of the interviews identified five major themes: generic medicines substitution trends, knowledge of and confidence with generic medicines, generic medicines marketing strategy, safety aspects of generic medicines labelling, and pharmacists' role in educating patients with respect to generic substitution. The results from this study indicate that, in general, community pharmacists are comfortable in offering generic substitution to their patients and they view generic medicine as being safe and effective in most situations. While views were mostly positive, there were a few concerns especially regarding substituting some specific drugs and problems associated with a patient's cognitive ability. The findings also suggested that pharmacists do not have a clear idea on the bioequivalence tests that are conducted for generic medicines by the medicine regulatory body, the Therapeutic Goods Administration (TGA) and they need more information pertaining to this. Issues pertaining to marketing of 'pseudo-generics' and the need for appropriate labelling of medicines to safeguard patients were also highlighted by some pharmacists interviewed. The pharmacist's role in advising patients on generic substitution was also seen as an important step to increase the uptake of generic medicines. Conclusion: This study suggested that despite pharmacists' positive attitudes to generic substitution, they need more education and information, especially on the methods required by the government authority to determine the bioequivalence of generic medicines.
SN  - 1538-5698
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106326199&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107354020
T1  - Geriatrics: unmasking 'polypharmacy' problems and adverse drug effects.
AU  - Duxbury AS
Y1  - 1996/04//
N1  - Accession Number: 107354020. Language: English. Entry Date: 19971201. Revision Date: 20150711. Publication Type: Journal Article; case study; tables/charts. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 750110. 
KW  - Polypharmacy -- Adverse Effects -- In Old Age
KW  - Iatrogenic Disease -- Chemically Induced -- In Old Age
KW  - Drug Therapy -- Adverse Effects -- In Old Age
KW  - Gerontologic Care
KW  - Pharmacokinetics -- In Old Age
KW  - Drug Interactions -- In Old Age
KW  - Patient Compliance -- In Old Age
KW  - Patient Education
KW  - Confusion -- Chemically Induced -- In Old Age
KW  - Accidental Falls -- In Old Age
KW  - Nutrition Disorders -- Chemically Induced -- In Old Age
KW  - Urinary Incontinence -- Chemically Induced -- In Old Age
KW  - Aged
KW  - Aged, 80 and Over
KW  - Female
KW  - Male
SP  - 762
EP  - 776 7p
JO  - Consultant (00107069)
JF  - Consultant (00107069)
JA  - CONSULTANT
VL  - 36
IS  - 4
CY  - Framingham, Massachusetts
PB  - United Business Media
AB  - Patients older than 65 years take an average of seven medications daily; more than 10% of geriatric admissions to general medical services are for medication reactions. Practical ways to reduce the danger of drug-induced disease and adverse drug reactions include frequent medication review and simplification of the medical regimen. Give both oral and written instructions, and check periodically to make sure instructions are being followed. Automatic prescription refilling and use of multiple physicians or pharmacies set the stage for polypharmacies set the stage for polypharmacy. Three investments in time and effort can greatly improve clinical outcomes and patient satisfaction: learning the adverse effects and interactions, treating the whole patient (not a disease), and explaining to patients that drugs are not the only way to manage a disease.
SN  - 0010-7069
AD  - University of California, Davis, School of Medicine
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107354020&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105927293
T1  - Health care providers' perceptions of the problems and causes of irrational use of drugs in two Middle East countries.
AU  - Otoom SA
AU  - Sequeira RP
Y1  - 2006/05//
N1  - Accession Number: 105927293. Language: English. Entry Date: 20080118. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Grant Information: Supported by WHO/EMRO. NLM UID: 9712381. 
KW  - Drug Utilization
KW  - Drugs, Prescription
KW  - Antibiotics -- Therapeutic Use
KW  - Antidiarrheals -- Therapeutic Use
KW  - Antiinflammatory Agents, Non-Steroidal -- Therapeutic Use
KW  - Data Analysis Software
KW  - Developing Countries
KW  - Drugs, Prescription -- Standards
KW  - Funding Source
KW  - Health Facilities
KW  - Jordan
KW  - Mann-Whitney U Test
KW  - Medical Records
KW  - Patient Education
KW  - Pharmacists
KW  - Physicians
KW  - Prescribing Patterns
KW  - Questionnaires
KW  - Self Medication
KW  - Syria
KW  - Human
SP  - 565
EP  - 570 6p
JO  - International Journal of Clinical Practice
JF  - International Journal of Clinical Practice
JA  - INT J CLIN PRACT
VL  - 60
IS  - 5
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - It is now evident that both developed and developing countries are experiencing many aspects of inappropriate use of drugs in their health care facilities. This is the first study in the region performed to examine the most common problems of irrational use of drugs and their causes in two Middle East countries - Jordan and Syria. Ninety senior participants from Jordan (50-15 physicians and 35 pharmacists) and Syria (40-12 physicians and 28 pharmacists) were enrolled in this study. The participants were asked to fill two questionnaires that deal with the problems and causes of irrational use of drugs in their country. Additionally, the participants were asked to perform a prescription analysis using WHO prescribing indicators on 40 prescriptions taken randomly from a comprehensive health centre in their country. The main drug use problems identified in the two countries were almost the same, but they vary in the percentage of occurrence and include excessive use of antibiotics and antidiarrhoeals, overprescribing of nonsteroidal anti-inflammatory drugs, prescribing by tradename, excessive use of antibiotics to treat minor upper respiratory infections and self-medication by the public. The main causes of irrational use of drugs were poor medical records, lack of patient education about illnesses and drugs, no family doctor system, lack of standard treatment guidelines and lack of continuing medical education for doctors and pharmacists. The results of this study are important for decision-makers to utilise when putting policies and strategies to improve the use of drugs in both countries.
SN  - 1368-5031
AD  - Department of Pharmacology and Therapeutics, Faculty of Medicine, Arabian Gulf University, Manama, Bahrain. sotoom@rcsi-mub.com
U2  - PMID: 16700856.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105927293&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107225865
T1  - HIV prevention among injecting drug users: responses in developing and transitional countries.
AU  - Ball AL
AU  - Rana S
AU  - Dehne KL
Y1  - 1998/06/02/1998 Jun Suppl 1
N1  - Accession Number: 107225865. Language: English. Entry Date: 19991101. Revision Date: 20150711. Publication Type: Journal Article; review; tables/charts. Supplement Title: 1998 Jun Suppl 1. Journal Subset: Biomedical; Peer Reviewed; Public Health; USA. NLM UID: 9716844. 
KW  - HIV Infections -- Prevention and Control -- Developing Countries
KW  - Substance Abuse, Intravenous -- Developing Countries
KW  - HIV Infections -- Epidemiology -- Developing Countries
KW  - Developing Countries
KW  - Literature Review
KW  - Acquired Immunodeficiency Syndrome -- Prevention and Control
KW  - Europe, Eastern
KW  - HIV Infections -- Transmission
KW  - Prevalence
KW  - Risk Taking Behavior -- Prevention and Control
KW  - Peer Counseling
KW  - Public Health
SP  - 170
EP  - 181 12p
JO  - Public Health Reports
JF  - Public Health Reports
JA  - PUBLIC HEALTH REP
VL  - 113
CY  - Washington, District of Columbia
PB  - Association of Schools & Programs of Public Health
AB  - Objectives. Human immunodeficiency virus (HIV) infection associated with injecting drug use has been reported in at least 98 countries and territories worldwide. There is evidence that new epidemics are emerging in different regions, including Eastern Europe, Latin America, and the eastern Mediterranean. The authors provide a global overview of the situation of HIV infection associated with injecting drug use and responses that have been implemented in various developing and transitional countries. Methods. Although there has been extensive documentation of the extent and nature of HIV infection associated with injecting drug use in many developed countries and the various interventions implemented in those countries, there is very limited information on the situation in developing and transitional countries. This chapter brings together information from a broad range of sources, including published literature; 'grey' or 'fugitive' literature; data collected by the World Health Organization (WHO), the joint United Nations Programme on HIV/AIDS (UNAIDS) and the United Nations International Drug Control Programme (UNDCP); personal communications; and direct observation by the authors. The authors have traveled extensively to a wide range of developing and transitional countries and have accessed information not readily available to the international research community. Results. A wide range of HIV prevention strategies targeting injecting drug users (IDUs) has been implemented in developing countries and countries in transition. Interventions include opioid substitution pharmacotherapy, needle syringe exchange and distribution, condom and bleach distribution, outreach to IDUs, peer education programs, and social network interventions. In some communities, completely new models of intervention and service delivery have developed in response to specific local needs and limitations. Conclusions. Although empirical data may currently be lacking to demonstrate the effectiveness of many HIV prevention programs targeting IDUs in developing and transitional countries, there is evidence that innovative HIV prevention initiatives are being implemented and sustained in a wide range of sociocultural settings.
SN  - 0033-3549
AD  - Programme on Substance Abuse, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland; email balla@who.ch
U2  - PMID: 9722822.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107225865&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104797478
T1  - HIV prevention and drug treatment services for drug misusers: a national study of community pharmacists' attitudes and their involvement in service specific training.
AU  - Sheridan, J
AU  - Strang, J
AU  - Taylor, C
AU  - Barber, N
Y1  - 1997/12//
N1  - Accession Number: 104797478. Language: English. Entry Date: 20110610. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9304118. 
KW  - Attitude of Health Personnel
KW  - HIV Infections -- Prevention and Control
KW  - Pharmacy, Retail
KW  - Professional Practice
KW  - Substance Use Disorders
KW  - Health Care Delivery
KW  - Education, Pharmacy
KW  - England
KW  - Wales
SP  - 1737
EP  - 1748 12p
JO  - Addiction
JF  - Addiction
JA  - ADDICTION
VL  - 92
IS  - 12
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - To investigate the attitudes of community pharmacists towards HIV prevention services for drug misusers and the relationship between these and their involvement in service provision. Postal survey of a one in four random sample of community pharmacies (N = 2654) in England and Wales, stratified by Family Health Service Authority, in 1995, using up to four mailshots. Community pharmacies in England and Wales. The community pharmacist in charge of the dispensary at the random sample of community pharmacies. Information on attitudes and behaviour were collected through self-completion and postal return of structured questionnaires using questions with both category responses and Likert scales. A 74.8% response rate was achieved. Community pharmacists were positive about their role in HIV prevention and the provision of clean injecting equipment to injecting drug users--positive attitudes that were more evident among those pharmacists already providing these services. However, they had concerns over the effect drug misusers may have on business and indicated a need for more training and for more role support. Only a minority had taken part in training on drug misuse and HIV prevention (34.7% and 21.3%, respectively). Many community pharmacists supported the proposal that there should be extensions of their involvement, to include services such as supervising the consumption of methadone in the pharmacy (38.6%) and collecting used prescribed ampoules from patients (33.8%). Positive relationships were identified between training and attitude, and between attitude and service provision. Changes in attitude responses between this 1995 survey and the earlier 1988 survey are also presented. Recommendations are made for further training and greater communication between prescriber/carer and the community pharmacists, for involvement of community pharmacies in new possible forms of service provision, and for there to be greater attention to the value of role support.
SN  - 0965-2140
AD  - National Addiction Centre, London, UK.
U2  - PMID: 9581006.
DO  - 10.1111/j.1360-0443.1997.tb02894.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107904365
T1  - How does use of a prescription monitoring program change pharmacy practice?
AU  - Green, Traci C
AU  - Mann, Marita R
AU  - Bowman, Sarah E
AU  - Zaller, Nickolas
AU  - Soto, Xaviel
AU  - Gadea, John
AU  - Cordy, Catherine
AU  - Kelly, Patrick
AU  - Friedmann, Peter D
Y1  - 2013/05//May/Jun2013
N1  - Accession Number: 107904365. Language: English. Entry Date: 20140425. Revision Date: 20150712. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 101176252. 
KW  - Analgesics, Opioid -- Administration and Dosage
KW  - Pharmacy Service -- Administration
KW  - Pharmacists -- Administration
KW  - Drug Therapy
KW  - Adult
KW  - Analgesics, Opioid -- Adverse Effects
KW  - Connecticut
KW  - Education, Pharmacy
KW  - Female
KW  - Surveys
KW  - Human
KW  - Male
KW  - Middle Age
KW  - Substance Use Disorders -- Prevention and Control
KW  - Patient Attitudes
KW  - Practice Patterns
KW  - Rhode Island
SP  - 273
EP  - 281 9p
JO  - Journal of the American Pharmacists Association: JAPhA
JF  - Journal of the American Pharmacists Association: JAPhA
JA  - J AM PHARM ASSOC
VL  - 53
IS  - 3
CY  - Washington, District of Columbia
PB  - American Pharmacists Association
SN  - 1544-3191
AD  - Rhode Island Hospital, 55 Claverick St., 2nd floor, Providence, RI 02903, USA. traci.c.green@gmail.com
U2  - PMID: 23699676.
DO  - 10.1331/JAPhA.2013.12094
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109759534
T1  - Impact of a clinical pharmacist-led guidance team on cancer pain therapy in china: a prospective multicenter cohort study.
AU  - Chen, Jian
AU  - Lu, Xiao-Yang
AU  - Wang, Wei-Jia
AU  - Shen, Bin
AU  - Ye, Yun
AU  - Jiang, Hong
AU  - Wang, Qi-Sheng
AU  - Cheng, Bin
Y1  - 2014/10//
N1  - Accession Number: 109759534. Language: English. Entry Date: 20150814. Revision Date: 20150923. Publication Type: Journal Article; clinical trial; research. Commentary: Waldfogel Julie M, Dy Sydney M. Multidisciplinary Management of Cancer Pain: Commentary on Chen et al. (J PAIN SYMPTOM MANAGE) Oct2014; 48 (4): 497-498. Journal Subset: Biomedical; Core Nursing; Nursing; Peer Reviewed; USA. Special Interest: Evidence-Based Practice; Pain and Pain Management; Palliative Care/Hospice. NLM UID: 8605836. 
KW  - Analgesics, Opioid -- Therapeutic Use
KW  - Neoplasms -- Epidemiology
KW  - Substance Use Disorders -- Epidemiology
KW  - Pain -- Drug Therapy
KW  - Pain -- Epidemiology
KW  - Multidisciplinary Care Team -- Statistics and Numerical Data
KW  - Pharmacists -- Statistics and Numerical Data
KW  - Causal Attribution
KW  - China
KW  - Prospective Studies
KW  - Comorbidity
KW  - Female
KW  - Human
KW  - Male
KW  - Neoplasms -- Nursing
KW  - Substance Use Disorders -- Prevention and Control
KW  - Pain -- Diagnosis
KW  - Pain Measurement -- Statistics and Numerical Data
KW  - Palliative Care -- Statistics and Numerical Data
KW  - Multidisciplinary Care Team -- Administration
KW  - Pharmacists -- Administration
KW  - Prevalence
KW  - Treatment Outcomes
KW  - Clinical Trials
SP  - 500
EP  - 509 10p
JO  - Journal of Pain & Symptom Management
JF  - Journal of Pain & Symptom Management
JA  - J PAIN SYMPTOM MANAGE
VL  - 48
IS  - 4
CY  - New York, New York
PB  - Elsevier Science
AB  - CONTEXT: Cancer treatment capacity in China is severely limited relative to the enormous size of the population; and many aspects of treatment, such as opioid protocols for pain control, are not standardized. To improve the quality of drug treatment, clinical pharmacists are taking a more active role in patient care. OBJECTIVES: This study compared the effectiveness of opioid treatment between cancer patients receiving interventions from Clinical Pharmacist-Led Guidance Teams (CPGTs) and a comparable control group. METHODS: This was a prospective, multicenter, double-arm, controlled study conducted in China. Multidisciplinary guidance teams were established and led by clinical pharmacists with expertise in cancer pain therapy. The CPGTs provided pre-therapy consultation and drug education to physicians, monitored prescriptions during treatment, and conducted patient follow-up. The process and outcome parameters of therapy were collected and analyzed with overall statistics and logistic regression. RESULTS: A total of 542 patients were enrolled, 269 in the CPGT intervention group (CPGT group) and 273 controls. Standardization of opioid administration was improved significantly in the CPGT group, including more frequent pain evaluation (P<0.001), more standardized dosing titration (P<0.001), and less frequent meperidine prescriptions (P<0.001). The pain scores in the CPGT group were significantly improved compared with the control group (P<0.05). The incidences of gastrointestinal adverse events were significantly lower in the CPGT group (constipation: P=0.041; nausea: P=0.028; vomiting: P=0.035), and overall quality of life was improved (P=0.032). No opioid addiction was encountered in the CPGT group. Risk analysis revealed that patient follow-up by pharmacists and the controlled dosing of opioids were the major factors in improving treatment efficacy. CONCLUSION: The CPGTs significantly improved standardization, efficiency, and efficacy of cancer pain therapy in China. In a country where clinical pharmacy is still developing, this is a valuable service model that may enhance cancer treatment capacity and efficacy while promoting recognition of the clinical pharmacy profession.
SN  - 0885-3924
AD  - Department of Pharmacy, The First Affiliated Hospital, College of Medicine, Zhejiang University, People's Republic of China.
AD  - Department of Pharmacy, The First Affiliated Hospital, College of Medicine, Zhejiang University, People's Republic of China. Electronic address: luxiaoyangzju@126.com.
AD  - Department of Pharmacy, Hangzhou Cancer Hospital, Hangzhou, People's Republic of China.
AD  - Department of Pharmacy, The First Hospital of Jiaxing, Jiaxing, People's Republic of China.
AD  - Department of Pharmacy, Beilun People's Hospital, Ningbo, People's Republic of China.
AD  - Department of Pharmacy, Shangyu People's Hospital, People's Republic of China.
AD  - Department of Pharmacy, People's Hospital of Xinchang County, Shaoxing, People's Republic of China.
AD  - Department of Pharmacy, Zhengjiang Cancer Hospital, Hangzhou, Zhejiang, People's Republic of China.
U2  - PMID: 24726204.
DO  - 10.1016/j.jpainsymman.2013.10.015
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109596416
T1  - Impact of a transition-of-care pharmacist during hospital discharge.
AU  - Balling, Lauren
AU  - Erstad, Brian L
AU  - Weibel, Kurt
Y1  - 2015/07//Jul/Aug2015
N1  - Accession Number: 109596416. Language: English. Entry Date: 20150923. Revision Date: 20160317. Publication Type: journal article; research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 101176252. 
SP  - 443
EP  - 448 6p
JO  - Journal of the American Pharmacists Association: JAPhA
JF  - Journal of the American Pharmacists Association: JAPhA
JA  - J AM PHARM ASSOC
VL  - 55
IS  - 4
CY  - Washington, District of Columbia
PB  - American Pharmacists Association
AB  - Objective: To assess the impact of a transition-of-care pharmacist during hospital discharge.Setting: An academic medical center in southern Arizona.Practice Description: One pharmacist coordinated patient discharges in two inpatient units from August 2012 through July 2013. The pharmacist attended interdisciplinary discharge coordination meetings, ensured appropriate discharge orders, facilitated the filling of medications, and educated patients on discharge medications.Practice Innovation: The implementation of a transition-of-care pharmacist to provide discharge medication reconciliation and education.Main Outcome Measures: Readmission rates and medication interventions made by the pharmacist at discharge.Results: The pharmacist was involved in the education of 1,011 patients and performed 452 interventions. There were more readmissions per month in the control year versus the year of pharmacist involvement (median 27.5 vs. 25, P = 0.0369). Interventions made by the pharmacist to improve discharge management included starting an omitted medication (23.5%), preventing multiple discharge problems (16.4%), avoiding duplication of therapy (15.7%), correcting insurance issues related to medication coverage (12.2%), changing an improper medication dose or quantity (11.3%), changing an inappropriate prescription for a medication (5.1%), preventing a drug interaction (3.3%), and resolving other problems (12.6%). The most common medication classes involved were antimicrobial agents (9.1%), anticoagulants (8%), antihyperglycemic agents (3.8%), other drug classes (24%), and multiple drug classes (35%).Conclusion: A transition-of-care pharmacist is in a unique position to educate patients on hospital discharge, to intercept a substantial number of medication errors, and to resolve insurance issues that may lead to adherence problems. These improvements in care may result in reduced hospital readmission rates.
SN  - 1544-3191
U2  - PMID: 26161488.
DO  - 10.1331/JAPhA.2015.14087
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106287028
T1  - Impact of commercial support on continuing pharmacy education.
AU  - Smith JL
AU  - Cervero RM
AU  - Valentine T
Y1  - 2006///Fall2006
N1  - Accession Number: 106287028. Language: English. Entry Date: 20070518. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Canada; Editorial Board Reviewed; Expert Peer Reviewed; Health Promotion/Education; Peer Reviewed. NLM UID: 8805847. 
KW  - Education, Continuing
KW  - Education, Pharmacy
KW  - Pharmaceutical Companies
KW  - Conflict of Interest
KW  - Evaluation Research
KW  - Program Evaluation
KW  - Questionnaires
KW  - Surveys
KW  - United States
KW  - Human
SP  - 302
EP  - 312 11p
JO  - Journal of Continuing Education in the Health Professions
JF  - Journal of Continuing Education in the Health Professions
JA  - J CONTIN EDUC HEALTH PROF
VL  - 26
IS  - 4
CY  - Hoboken, New Jersey
PB  - John Wiley & Sons, Inc.
AB  - Introduction: There is a serious debate over the involvement of the pharmaceutical industry in continuing education. Policies that govern the planning of continuing education for pharmacists center on the potential conflict of interest when there is commercial support for programs. The purpose of this study was to investigate the impact of commercial support on the provision and perceived outcomes of continuing pharmacy education.Methods: A survey was administered online to a national sample of accredited providers of continuing pharmacy education, resulting in 134 responses. The 64-item survey was developed to measure the planning practices of these providers and their perceptions of the educational and noneducational consequences of commercial support for continuing education.Results: One hundred thirty-four usable questionnaires (34%) were received from 386 leaders in pharmacy education. Approximately 86% of providers and 43% of programs received commercial support. Although the Accreditation Council for Pharmacy Education requires that providers review instructional content and materials for commercially supported programs before delivery, only 43% always did so. Commercial support was perceived to have consequences for provider organizations, pharmacists, and patients, such as increased cost and use of drugs and financial dependency of providers and participants on industry support.Discussion: The results of our study lead to the conclusions that commercial support of continuing education is widespread, affects continuing education programs, and is perceived to have significant educational and noneducational consequences. The profession should ensure that continuing education guidelines are unambiguous related to specific practices that are allowable and unallowable when receiving commercial support. Future research should study the consequences of commercial support behaviorally by examining the effects on pharmacy professionals' practice and pharmaceutical care.
SN  - 0894-1912
AD  - Office of Faculty Affairs, University of Georgia, Athens.
U2  - PMID: 17163494.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106535846
T1  - Impact of counterfeit drugs on the formulary decision-making process.
AU  - Redwanski J
AU  - Seamon MJ
Y1  - 2004/12//
N1  - Accession Number: 106535846. Language: English. Entry Date: 20051104. Revision Date: 20150711. Publication Type: Journal Article; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9513311. 
KW  - Counterfeit Drugs
KW  - Decision Making
KW  - Formularies -- Standards
KW  - Safety -- Standards
KW  - Formularies -- Legislation and Jurisprudence
KW  - Professional Role
KW  - Safety -- Legislation and Jurisprudence
KW  - United States Food and Drug Administration
SP  - 577
EP  - 583 4p
JO  - Formulary
JF  - Formulary
JA  - FORMULARY
VL  - 39
IS  - 12
CY  - North Olmsted, Ohio
PB  - Advanstar Communications Inc.
AB  - As initiatives to legalize the importation of prescription drugs draw more attention, the concern over counterfeit drugs is growing. The possibility of receiving counterfeit drugs has created an emerging dilemma for health-care professionals. FDA is relying on pharmacists to help ensure the integrity of drug products before they reach health-care consumers. Pharmacy and therapeutics committees can play a key role in achieving this goal by reviewing policies for medication acquisition and ensuring that necessary controls are in place to help prevent the acquisition of counterfeit drugs. FDA is also taking steps to help alleviate counterfeiting by mandating bar codes on all hospital drug packaging and implementing electronic pedigree papers to track distribution. FDA leaders project that by 2007, all prescription drugs will be tracked electronically to help ensure their authenticity. Formulary decision-makers, pharmacy directors, and clinicians must continue to be educated about the problem to help pre-vent counterfeit drugs from polluting the drug supply.
SN  - 1082-801X
AD  - Drug Information Specialist, Drug Information Center, Hampton University, Hampton, VA; john.redwanski2@hamptonu.edu
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106080803
T1  - Impact of pharmacist-conducted home visits on the outcomes of lipid-lowering drug therapy.
AU  - Peterson GM
AU  - Fitzmaurice KD
AU  - Naunton M
AU  - Vial JH
AU  - Stewart K
AU  - Krum H
Y1  - 2004/02//
N1  - Accession Number: 106080803. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article; clinical trial; research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 8704308. 
KW  - Antilipemic Agents -- Therapeutic Use
KW  - Cardiovascular Diseases -- Drug Therapy
KW  - Home Visits
KW  - Pharmacists
KW  - Aged
KW  - Cholesterol -- Blood
KW  - Clinical Trials
KW  - Female
KW  - Health Behavior
KW  - Male
KW  - Middle Age
KW  - Patient Compliance
KW  - Patient Education -- Methods
KW  - Prospective Studies
KW  - Treatment Outcomes
KW  - Human
SP  - 23
EP  - 30 8p
JO  - Journal of Clinical Pharmacy & Therapeutics
JF  - Journal of Clinical Pharmacy & Therapeutics
JA  - J CLIN PHARM THER
VL  - 29
IS  - 1
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - To evaluate a pharmacist-conducted educational and monitoring programme, designed to promote dietary and lifestyle modification and compliance with lipid-lowering drug therapy, for patients with dyslipidaemia. This was a prospective, randomized, controlled study. The participants were 94 adults, with 81 completing the study (intervention group: 39; control group: 42), with a cardiovascular-related diagnosis and discharged from hospital, between April and October 2001, on lipid-lowering drug therapy. Patients in the intervention group were visited at home monthly by a pharmacist, who educated the patients on the goals of lipid-lowering treatment and the importance of lifestyle issues in dyslipidaemia and compliance with therapy, assessed patients for drug-related problems, and measured total blood cholesterol levels using point-of-care testing. Patients in the control group received standard medical care. The main outcome measure was total blood cholesterol levels after 6 months, and an evaluation of patient and general practitioner satisfaction with the programme. There was no significant difference in baseline total blood cholesterol levels between the two groups. The reduction over the course of the study in cholesterol levels within the intervention group was statistically significant (4·9 ±0·7 to 4·4 ± 0·6, P < 0·005), whereas there was no change within the control group ( P = 0·26). At follow-up, 44% of the intervention group patients and 24% of the control group patients had cholesterol levels below 4·0 mmol/L ( P = 0·06). The reduction in total cholesterol in the intervention group should translate to an expected 21% reduction in cardiovascular mortality risk and a 16% reduction in total mortality risk - more than twice the risk reduction achieved in the control group. In addition, the programme was very well received by the patients and their general practitioners, by satisfaction questionnaire. A pharmacist-conducted educational and monitoring intervention improved the outcomes of lipid-lowering drug therapy.
SN  - 0269-4727
U2  - PMID: 14748894.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103910671
T1  - Impact of the Pharmacist Medication Review Services on Drug-Related Problems and Potentially Inappropriate Prescribing of Renally Cleared Medications in Residents of Aged Care Facilities.
AU  - Gheewala, Pankti
AU  - Peterson, Gregory
AU  - Curtain, Colin
AU  - Nishtala, Prasad
AU  - Hannan, Paul
AU  - Castelino, Ronald
Y1  - 2014/11//
N1  - Accession Number: 103910671. Language: English. Entry Date: 20141029. Revision Date: 20150710. Publication Type: Journal Article; research; tables/charts. Journal Subset: Australia & New Zealand; Biomedical; Peer Reviewed. Special Interest: Gerontologic Care. NLM UID: 9102074. 
KW  - Inappropriate Prescribing -- Evaluation
KW  - Human
KW  - Aged
KW  - Residential Care
KW  - Pharmacists
KW  - Kidney Function Tests -- Evaluation
KW  - Australia
KW  - Descriptive Statistics
KW  - Interrater Reliability
SP  - 825
EP  - 835 11p
JO  - Drugs & Aging
JF  - Drugs & Aging
JA  - DRUGS AGING
VL  - 31
IS  - 11
PB  - Springer Science & Business Media B.V.
AB  - Background: Drug-related problems (DRPs) are common in aged care facilities and few studies have been conducted to determine the impact of the pharmacist-conducted medication review services. Studies determining the prevalence of chronic kidney disease (CKD) and data regarding inappropriate prescribing of renally cleared medications in aged care facilities in Australia are also lacking. Objectives: To investigate the number and nature of DRPs identified and recommendations made by pharmacists in residents of aged care facilities. To determine the prevalence of CKD and estimate the magnitude of inappropriate prescribing of renally cleared medications in residents of aged care facilities. Methods: DRPs identified and recommendations made by pharmacists were classified using the adapted version of the DOCUMENT classification system. The modification of diet in renal disease formula was used to estimate the prevalence of CKD, and the Cockcroft-Gault formula was used to estimate the magnitude of inappropriate prescribing of renally cleared medications. Results: Over 98 % of residents of aged care facilities had at least one DRP. Most (83.8 %) recommendations made by accredited pharmacists to resolve DRPs were accepted by general practitioners. CKD was prevalent in 48 % of residents, and inappropriate prescribing of renally cleared medications was identified in 28 (16 %) residents with CKD. Conclusions: DRPs are common in aged care facilities and the impact of medication review services appears to be high. CKD is also common among residents of aged care facilities, and inappropriate prescribing of renally cleared medications was also prevalent, warranting attention to regular renal function monitoring and appropriate drug and dose selection in residents of aged care facilities.
SN  - 1170-229X
AD  - School of Medicine, University of Tasmania, Private Bag 26 Hobart 7001 Australia
AD  - School of Pharmacy, University of Otago, Dunedin New Zealand
AD  - Meditrax, Sydney Australia
U2  - PMID: 25187228.
DO  - 10.1007/s40266-014-0208-y
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104117342
T1  - Implementation of a pharmacist-driven pain management consultation service for hospitalised adults with a history of substance abuse.
AU  - Andrews, L B
AU  - Bridgeman, M B
AU  - Dalal, K S
AU  - Abazia, D
AU  - Lau, C
AU  - Goldsmith, D F
AU  - John, D St
Y1  - 2013/12//
N1  - Accession Number: 104117342. Language: English. Entry Date: 20140718. Revision Date: 20150710. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9712381. 
KW  - Analgesics, Opioid -- Supply and Distribution
KW  - Pain -- Prevention and Control
KW  - Pharmacy Service -- Utilization
KW  - Substance Use Disorders -- Complications
KW  - Adult
KW  - Analgesics, Opioid -- Therapeutic Use
KW  - Health Care Delivery
KW  - Hospitalization -- Statistics and Numerical Data
KW  - Academic Medical Centers -- Statistics and Numerical Data
KW  - Human
KW  - New Jersey
KW  - Multidisciplinary Care Team -- Statistics and Numerical Data
KW  - Physician-Patient Relations
KW  - Pilot Studies
KW  - Urban Health
SP  - 1342
EP  - 1349 8p
JO  - International Journal of Clinical Practice
JF  - International Journal of Clinical Practice
JA  - INT J CLIN PRACT
VL  - 67
IS  - 12
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - BACKGROUND: Pain management in adult patients with concomitant substance use disorders (SUDs) presents a clinical challenge in the absence of objective assessment criteria. Effective pain management is dependent on the clinician's ability to differentiate true pain symptoms from manipulative behaviours. Successful strategies for achieving effective pain control in these patients include implementing a multidisciplinary team approach, use of non-opioid and non-pharmacologic alternatives, and judicious use of opioid analgesics. OBJECTIVE: To describe the implementation of a pharmacist-driven pain management service for patients with concomitant SUDs. METHODS: In an urban teaching hospital located in Trenton, New Jersey, United States, a clinical pharmacist-led pain management service evolved to provide formal consultation. Standardised assessment and treatment approaches were developed to assure consistency. Multidisciplinary education was provided to the medical staff. MAIN OUTCOME MEASURE: The study describes a variety of patterns associated with the program from its pilot period through the first 6 years of service, including opioid utilisation, volume and source of consultations, and multidisciplinary perceptions regarding the program's impact. RESULTS: The establishment of a pharmacist-led pain management consult service successfully addressed patient's needs while modifying drug-seeking behaviours. A significant decrease in opioid usage was noted during the program's pilot period and sustained over time. The program's success has extended the pharmacist's role beyond the program's initial scope to address general pain management needs and to address educational needs of the medical staff. Today, clinical pharmacists are utilised most often for refractory cases for which the most appropriate method of pain management may not be clear.
SN  - 1368-5031
AD  - Department of Pharmacy Practice and Administration, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, New Jersey.
U2  - PMID: 24246213.
DO  - 10.1111/ijcp.12311
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 104496631
T1  - Implementation of a substance abuse awareness program for high school students and parents.
AU  - Gershman, Jennifer A.
Y1  - 2012/09//9/1/2012
N1  - Accession Number: 104496631. Language: English. Entry Date: 20120823. Revision Date: 20150711. Publication Type: Journal Article; letter. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Substance Abuse -- Prevention and Control
KW  - Students, High School
KW  - Parental Role
KW  - Drugs, Prescription -- Adverse Effects
KW  - Health Promotion -- Education
KW  - Analgesics
KW  - Pharmacists
KW  - Students, Pharmacy
KW  - Teachers
KW  - Program Implementation -- Methods
KW  - Curriculum Development
KW  - Website Development
KW  - Parent-Child Relations
KW  - Interprofessional Relations
SP  - 1464
EP  - 1466 3p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 69
IS  - 17
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
SN  - 1079-2082
AD  - Assistant Professor, Department of Pharmacy Practice, College of Pharmacy, Nova Southeastern University, Fort Lauderdale, FL
U2  - PMID: 22899740.
DO  - 10.2146/ajhp120092
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ER  - 

TY  - JOUR
ID  - 108205756
T1  - Improving drug labeling and counseling for limited english proficient adults.
AU  - Bailey, Stacy Cooper
AU  - Agarwal, Nisha
AU  - Sleath, Betsy
AU  - Gumusoglu, Serena
AU  - Wolf, Michael S
Y1  - 2011/11//
N1  - Accession Number: 108205756. Language: English. Entry Date: 20120106. Revision Date: 20150712. Publication Type: Journal Article; review. Journal Subset: Health Services Administration; Peer Reviewed; Public Health; USA. Special Interest: Public Health. NLM UID: 9103800. 
KW  - Counseling
KW  - Drug Labeling
KW  - Drug Therapy
KW  - Drugs, Prescription
KW  - English as a Second Language
KW  - Civil Rights
KW  - Communication Barriers
KW  - Health Policy
KW  - Health Services Accessibility
KW  - Information Literacy
KW  - Interpreter Services
KW  - Patient Education
KW  - Pharmacists
KW  - Physicians
KW  - Primary Health Care
SP  - 1131
EP  - 1143 13p
JO  - Journal of Health Care for the Poor & Underserved
JF  - Journal of Health Care for the Poor & Underserved
JA  - J HEALTH CARE POOR UNDERSERV
VL  - 22
IS  - 4
CY  - Baltimore, Maryland
PB  - Johns Hopkins University Press
AB  - Abstract:Language barriers between patients and providers adversely affect quality of care and a patient's ability to obtain, understand, and act on health information. Health care organizations are mandated by law to provide language concordant services. While health systems have taken steps to promote language access, minimal effort has been made to improve pharmacy practice. This is problematic, as patient misunderstanding of prescription drug instructions is a root cause of many adverse drug events occurring annually in outpatient settings. Enhanced, language concordant prescription labeling and counseling is needed to promote safe use of prescription medications among limited English proficient patients.
SN  - 1049-2089
U2  - PMID: 22080698.
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ER  - 

TY  - JOUR
ID  - 106779629
T1  - Improving patient care. The quality of pharmacologic care for vulnerable older patients.
AU  - Higashi T
AU  - Shekelle PG
AU  - Solomon DH
AU  - Knight EL
AU  - Roth C
AU  - Chang JT
AU  - Kamberg CJ
AU  - MacLean CH
AU  - Young RT
AU  - Adams J
AU  - Reuben DB
AU  - Avorn J
AU  - Wenger NS
Y1  - 2004/05/04/
N1  - Accession Number: 106779629. Language: English. Entry Date: 20040924. Revision Date: 20150711. Publication Type: Journal Article; consumer/patient teaching materials; research; tables/charts. Journal Subset: Biomedical; Expert Peer Reviewed; Peer Reviewed; USA. Grant Information: Pfizer Inc, a National Research Service Award (PE-19001) and the University of California, Los Angeles, Specialty Training and Advanced Research (STAR) Program. NLM UID: 0372351. 
KW  - Drug Therapy -- Standards -- In Old Age
KW  - Clinical Indicators
KW  - Drugs, Prescription -- Standards
KW  - Patient Education
KW  - Continuity of Patient Care
KW  - Managed Care Programs
KW  - Prospective Studies
KW  - Random Sample
KW  - Chi Square Test
KW  - Confidence Intervals
KW  - Aged
KW  - Funding Source
KW  - Human
SP  - 714
EP  - I52 8p
JO  - Annals of Internal Medicine
JF  - Annals of Internal Medicine
JA  - ANN INTERN MED
VL  - 140
IS  - 9
CY  - Philadelphia, Pennsylvania
PB  - American College of Physicians
AB  - BACKGROUND: Although pharmacotherapy is critical to the medical care of older patients, medications can have considerable toxicity in this age group. To date, research has focused on inappropriate prescribing and policy efforts have aimed at access, but no comprehensive measurement of the quality of pharmacologic management using explicit criteria has been performed. OBJECTIVE: To evaluate the broad range of pharmacologic care processes for vulnerable older patients. DESIGN: Observational cohort study. SETTING: 2 managed care organizations enrolling older persons. PATIENTS: Community-dwelling high-risk patients 65 years of age or older continuously enrolled in the managed care organizations from 1 July 1998 to 31 July 1999. MEASUREMENTS: Patients' receipt of care as specified in 43 quality indicators covering 4 domains of pharmacologic care: 1) prescribing indicated medications; 2) avoiding inappropriate medications; 3) education, continuity, and documentation; and 4) medication monitoring. RESULTS: Of 475 vulnerable older patients, 372 (78%) consented to participate and had medical records that could be abstracted. The percentage of appropriate pharmacologic management ranged from 10% for documentation of risks of nonsteroidal anti-inflammatory drugs to 100% for avoiding short-acting calcium-channel blockers in patients with heart failure and avoiding beta-blockers in patients with asthma. Pass rates for quality indicators in the 'avoiding inappropriate medications' domain (97% [95% CI, 96% to 98%]) were significantly higher than pass rates for 'prescribing indicated medications' (50% [CI, 45% to 55%]); 'education, continuity, and documentation' (81% [CI, 79% to 84%]); and 'medication monitoring' (64% [CI, 60% to 68%]). LIMITATIONS: Fewer than 10 patients were eligible for many of the quality indicators measured, and the generalizability of these findings in 2 managed care organizations to the general geriatric population is uncertain. CONCLUSIONS: Failures to prescribe indicated medications, monitor medications appropriately, document necessary information, educate patients, and maintain continuity are more common prescribing problems than use of inappropriate drugs in older patients.
SN  - 0003-4819
AD  - Division of General Internal Medicine, University of California, Los Angeles, 911 Broxton Plaza, Los Angeles, CA 90095
U2  - PMID: 15126255.
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 103759322
T1  - Improving Population Management through Pharmacist-Primary Care Integration: A Pilot Study.
AU  - Kennedy, Amanda G.
AU  - Chen, Harry
AU  - Corriveau, Michele
AU  - MacLean, Charles D.
Y1  - 2015/02//
N1  - Accession Number: 103759322. Language: English. Entry Date: 20150217. Revision Date: 20160201. Publication Type: Journal Article; research; tables/charts. Journal Subset: Health Services Administration; Peer Reviewed; USA. Special Interest: Case Management. Grant Information: Vermont Department of Health.. NLM UID: 101481266. 
KW  - Primary Health Care -- Vermont
KW  - Pharmacists -- Utilization
KW  - Health Care Delivery, Integrated -- Vermont
KW  - Quality Improvement
KW  - Human
KW  - Pilot Studies -- Vermont
KW  - Vermont
KW  - Funding Source
KW  - Patient Centered Care
KW  - Staff Development
KW  - Consultants
KW  - Cost Savings
KW  - Adverse Drug Event -- Prevention and Control
KW  - Multicenter Studies
KW  - Job Characteristics
KW  - Descriptive Statistics
KW  - Computerized Patient Record -- Utilization
SP  - 23
EP  - 29 7p
JO  - Population Health Management
JF  - Population Health Management
JA  - POPUL HEALTH MANAGE
VL  - 18
IS  - 1
CY  - New Rochelle, New York
PB  - Mary Ann Liebert, Inc.
AB  - Pharmacists have unique skills that may benefit primary care practices. The objective of this demonstration project was to determine the impact of integrating pharmacists into patient-centered medical homes, with a focus on population management. Pharmacists were partnered into 5 primary care practices in Vermont 1 day per week to provide direct patient care, population-based medication management, and prescriber education. The main measures included a description of drug therapy problems identified and cost avoidance models. The pharmacists identified 708 drug therapy problems through direct patient care (336/708; 47.5%), population-based strategies (276/708; 38.9%), and education (96/708; 13.6%). Common population-based strategies included adjusting doses and discontinuing unnecessary medications. Pharmacists' recommendations to correct drug therapy problems were accepted by prescribers 86% of the time, when data about acceptance were known. Of the 49 recommendations not accepted, 47/49 (96%) were population-based and 2/49 (4%) were related to direct patient care. The cost avoidance model suggests $2.11 in cost was avoided for every $1.00 spent on a pharmacist ($373,092/$176,690). There was clear value in integrating pharmacists into primary care teams. Their inclusion prevented adverse drug events, avoided costs, and improved patient outcomes. Primary care providers should consider pharmacists well suited to offer direct patient care, population-based management, and prescriber education to their practices. To be successful, pharmacists must have full permission to document findings in the primary care practices' electronic health records. Given that many pharmacist services do not involve billable activities, sustainability requires identifying alternative funding mechanisms that do not rely on a traditional fee-for-service approach. ( Population Health Management 2015;18:23-29)
SN  - 1942-7891
AD  - Division of General Internal Medicine, University of Vermont College of Medicine, Burlington, Vermont.
AD  - Vermont Department of Health, Burlington, Vermont.
AD  - Department of Pharmacy, Fletcher Allen Health Care, Burlington, Vermont.
U2  - PMID: 25029631.
DO  - 10.1089/pop.2014.0043
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105439661
T1  - In brief.
Y1  - 2009/08//
N1  - Accession Number: 105439661. Language: English. Entry Date: 20091030. Revision Date: 20150711. Publication Type: Journal Article; brief item. Journal Subset: Biomedical; Continental Europe; Europe. 
KW  - Antiviral Agents
KW  - Awards and Honors
KW  - Business
KW  - Ephedrine -- Legislation and Jurisprudence
KW  - Pharmacy, Retail -- Legislation and Jurisprudence
KW  - Prescriptive Authority
KW  - Students, Pharmacy
KW  - Substance Abuse
SP  - 4
EP  - 6 2p
JO  - Pharmacy News
JF  - Pharmacy News
JA  - PHARM NEWS
PB  - Cirrus Media
SN  - 1448-207X
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 107296347
T1  - In my experience. Insulin as an anabolic aid? A danger for strength athletes.
AU  - Willey JW II
Y1  - 1997/10//
N1  - Accession Number: 107296347. Language: English. Entry Date: 19981101. Revision Date: 20150820. Publication Type: Journal Article; CEU; exam questions; tables/charts. Journal Subset: Allied Health; Peer Reviewed; USA. NLM UID: 0427461. 
KW  - Doping in Sports
KW  - Insulin
KW  - Athletes
KW  - Substance Abuse
KW  - Insulin -- Adverse Effects
KW  - Hypoglycemia
KW  - Education, Continuing (Credit)
SP  - 103
EP  - 138 5p
JO  - Physician & Sportsmedicine
JF  - Physician & Sportsmedicine
JA  - PHYSICIAN SPORTSMED
VL  - 25
IS  - 10
CY  - Philadelphia, Pennsylvania
PB  - Taylor & Francis Ltd
AB  - A young, nondiabetic weight lifter became pale, diaphoretic, and markedly distressed while dining out; intuition and quick action may have saved his life. His case illustrates the perils of taking insulin for anabolic purposes. Physicians must learn to question patients about nutritional and pharmacologic supplement use to help them avoid the dangers not typically addressed in the popular fitness and alternative medicine literature.
SN  - 0091-3847
AD  - Mayo Clinic, Scottsdale, Arizona
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ER  - 

TY  - JOUR
ID  - 109688119
T1  - In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile.
AU  - Kuo, A
AU  - Wyse, B D
AU  - Meutermans, W
AU  - Smith, M T
Y1  - 2015/01/15/
N1  - Accession Number: 109688119. Language: English. Entry Date: 20150923. Revision Date: 20160115. Publication Type: journal article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 7502536. 
SP  - 532
EP  - 548 17p
JO  - British Journal of Pharmacology
JF  - British Journal of Pharmacology
JA  - BR J PHARMACOL
VL  - 172
IS  - 2
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Background and Purpose: For patients experiencing inadequate analgesia and intolerable opioid-related side effects on one strong opioid analgesic, pain relief with acceptable tolerability is often achieved by rotation to a second strong opioid. These observations suggest subtle pharmacodynamic differences between opioids in vivo. This study in rats was designed to assess differences between opioids in their in vivo profiles.Experimental Approach: Male Sprague Dawley rats were given single i.c.v. bolus doses of morphine, morphine-6-glucuronide (M6G), fentanyl, oxycodone, buprenorphine, DPDPE ([D-penicillamine(2,5) ]-enkephalin) or U69,593. Antinociception, constipation and respiratory depression were assessed using the warm water tail-flick test, the castor oil-induced diarrhoea test and whole body plethysmography respectively.Key Results: These opioid agonists produced dose-dependent antinociception, constipation and respiratory depression. For antinociception, morphine, fentanyl and oxycodone were full agonists, buprenorphine and M6G were partial agonists, whereas DPDPE and U69,593 had low potency. For constipation, M6G, fentanyl and buprenorphine were full agonists, oxycodone was a partial agonist, morphine produced a bell-shaped dose-response curve, whereas DPDPE and U69,593 were inactive. For respiratory depression, morphine, M6G, fentanyl and buprenorphine were full agonists, oxycodone was a partial agonist, whereas DPDPE and U69,593 were inactive. The respiratory depressant effects of fentanyl and oxycodone were of short duration, whereas morphine, M6G and buprenorphine evoked prolonged respiratory depression.Conclusion and Implications: For the seven opioids we assessed, no two had the same profile for evoking antinociception, constipation and respiratory depression, suggesting that these effects are differentially regulated. Our findings may explain the clinical success of 'opioid rotation'.Linked Articles: This article is part of a themed section on Opioids: New Pathways to Functional Selectivity. To view the other articles in this section visit http://dx.doi.org/10.1111/bph.2015.172.issue-2.
SN  - 0007-1188
U2  - PMID: 24641546.
DO  - 10.1111/bph.12696
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ER  - 

TY  - JOUR
ID  - 105893781
T1  - Individual differences in adoption of treatment for smoking cessation: Demographic and smoking history characteristics.
AU  - Shiffman S
AU  - Brockwell SE
AU  - Pillitteri JL
AU  - Gitchell JG
Y1  - 2008/01/11/
N1  - Accession Number: 105893781. Language: English. Entry Date: 20080418. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology. NLM UID: 7513587. 
KW  - Attitude to Health
KW  - Health Behavior
KW  - Patient Attitudes
KW  - Smoking Cessation
KW  - Smoking -- Epidemiology
KW  - Smoking -- Therapy
KW  - Adolescence
KW  - Adult
KW  - Cognitive Therapy
KW  - Demography
KW  - Drug Therapy -- Statistics and Numerical Data
KW  - Female
KW  - Incidence
KW  - Male
KW  - Middle Age
KW  - Prevalence
KW  - Questionnaires
KW  - Human
SP  - 121
EP  - 131 11p
JO  - Drug & Alcohol Dependence
JF  - Drug & Alcohol Dependence
JA  - DRUG ALCOHOL DEPENDENCE
VL  - 93
IS  - 1/2
PB  - Elsevier Science
AB  - BACKGROUND: Behavioral and pharmacological treatments have been shown to improve smoking cessation rates, but treatments are under-utilized. AIMS: To examine the demographic and smoking history characteristics associated with adoption of treatment for cessation. DESIGN: Analysis of the 2003 tobacco use special cessation supplement to the current population survey. PARTICIPANTS: Representative sample of 12,027 U.S. daily smokers ages 18 and older who made a quit attempt in the past year. MEASUREMENTS: Use of behavioral, pharmacological or alternative treatments for cessation; demographic variables (age, gender, ethnicity, education and income) and measures of nicotine dependence. RESULTS: Females, Whites, older, more educated and wealthier smokers were more likely to adopt treatment in a quit attempt, as were more nicotine dependent smokers. Females were more likely than males to use behavioral treatments. Females and more educated smokers were more likely to combine behavioral and pharmacological treatment. Among those who used only one treatment, males, older and more nicotine dependent smokers were more likely to adopt pharmacological treatments. CONCLUSIONS: The majority of smokers make quit attempts without the benefit of proven behavioral or pharmacological treatments. Efforts are needed to increase use of smoking cessation treatments among all smokers, particularly combination treatment.
SN  - 0376-8716
U2  - PMID: 17996399.
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DB  - ccm
ER  - 

TY  - JOUR
ID  - 105572555
T1  - Individuals appreciate having their medication record on the web: a survey of attitudes to a national pharmacy register.
AU  - Montelius E
AU  - Astrand B
AU  - Hovstadius B
AU  - Petersson G
Y1  - 2008/10//
N1  - Accession Number: 105572555. Language: English. Entry Date: 20090529. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Canada; Computer/Information Science; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed. Special Interest: Informatics. NLM UID: 100959882. 
KW  - Attitude to Computers
KW  - Automation
KW  - Drug Therapy
KW  - Electronics -- Standards
KW  - Internet
KW  - Medical Informatics -- Standards
KW  - Medication Systems -- Standards
KW  - Data Collection
KW  - Power
KW  - Risk Assessment
KW  - Human
SP  - e35
EP  - e35 1p
JO  - Journal of Medical Internet Research
JF  - Journal of Medical Internet Research
JA  - J MED INTERNET RES
VL  - 10
IS  - 4
CY  - Toronto, Ontario
PB  - JMIR Publications Inc.
AB  - BACKGROUND: Many patients receive health care in different settings. Thus, a limitation of clinical care may be inaccurate medication lists, since data exchange between settings is often lacking and patients do not regularly self-report on changes in their medication. Health care professionals and patients are both interested in utilizing electronic health information. However, opinion is divided as to who should take responsibility for maintaining personal health records. In Sweden, the government has passed a law to enforce and fund a national register of dispensed medications. The register comprises all individuals with dispensed medications (6.4 million individuals, September 2006) and can be accessed by the individual online via 'My dispensed medications'. The individual has the right to restrict the accessibility of the information in health care settings. OBJECTIVE: The aim of the present study was to evaluate the users' attitudes towards their access to 'My dispensed medications' as part of a new interactive Internet service on prescribed medications. METHOD: A password-protected Web survey was conducted among a first group of users of 'My dispensed medications'. Data was anonymously collected and analyzed with regard to the usefulness and design of the Web site, the respondents' willingness to discuss their 'My dispensed medications' with others, their reasons for access, and their source of information about the service. RESULTS: During the study period (January-March, 2007), all 7860 unique site visitors were invited to answer the survey. Invitations were accepted by 2663 individuals, and 1716 responded to the online survey yielding a view rate of 21.8% (1716/7860) and a completion rate of 64.4% (1716/2663). The completeness rate for each question was in the range of 94.9% (1629/1716) to 99.5% (1707/1716). In general, the respondents' expectations of the usefulness of 'My dispensed medications' were high (total median grade 5; Inter Quartile Range [IQR] 3, on a scale 1-6). They were also positive about the design of the Web site (total median grade 5; IQR 1, on a scale 1-6). The high grades were not dependent on age or number of drugs. A majority of the respondents, 60.4% (1037/1716), had learned about 'My dispensed medications' from pharmacies. 70.4% (1208/1716) of all respondents said they visited 'My dispensed medications' to get control or an overview of their drugs. Getting control was a more common (P < .001) answer for the elderly (age 75 or above), whereas curiosity was more common (P < .001) for the younger age group (18-44 years). CONCLUSION: We found that users of the provider-based personal medication record 'My dispensed medications' appreciated the access to their record. Since we found that the respondents liked the design of the Web site and perceived that the information was easy to understand, the study provided no reason for system changes. However, a need for more information about the register, and to extend its use, was recognized.
SN  - 1438-8871
AD  - E-Health Institute, University of Kalmar, Kalmar, Sweden. emelie.montelius@hik.se
U2  - PMID: 19000978.
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ER  - 

TY  - JOUR
ID  - 106765447
T1  - Injecting behaviour of injecting drug users at needle and syringe programmes and pharmacies in Australia.
AU  - Thein H
AU  - Denoe M
AU  - van Beek I
AU  - Dore G
AU  - MacDonald M
Y1  - 2003/12//
N1  - Accession Number: 106765447. Language: English. Entry Date: 20040813. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9014759. 
KW  - Needle Exchange Programs
KW  - Pharmacy, Retail
KW  - Substance Abuse, Intravenous -- Evaluation -- Australia
KW  - Syringes -- Economics
KW  - Adolescence
KW  - Adult
KW  - Australia
KW  - Comparative Studies
KW  - Data Analysis, Statistical
KW  - Female
KW  - Male
KW  - Middle Age
KW  - Questionnaires
KW  - Risk Taking Behavior
KW  - Human
SP  - 425
EP  - 430 6p
JO  - International Journal of Drug Policy
JF  - International Journal of Drug Policy
JA  - INT J DRUG POLICY
VL  - 14
IS  - 5/6
CY  - New York, New York
PB  - Elsevier Science
AB  - Objective: To compare demographic and injecting characteristics of clients collecting needle syringes from needle syringe programmes (NSPs) and pharmacies. Methods: Clients obtaining needle syringes from three NSPs and one pharmacy in the same geographic area during one and four weeks, respectively were asked to complete a self-administered questionnaire. Results: Approximately half the 336 NSP (56%) and 63 pharmacy (49%) respondents reported using both NSPs and pharmacies in the past month. NSP and pharmacy respondents were similar on many characteristics: male gender (60 and 62%, respectively); median age (30 years for both groups); median age at first injection (18 years both groups); history of methadone treatment (62 and 53%); and heroin as the last drug injected (60 and 59%). NSP respondents were more likely than pharmacy respondents to report imprisonment in the previous year (20% versus 8%, P=0.05), daily injection (67% versus 56%, P=0.09) and re-use of more than one other person's needle syringe in the previous month (27% versus 7% of 52 and 15 reporting needle syringe re-use). Pharmacy respondents were more likely than NSP respondents to report amphetamine use (32% versus 10%, P<0.001), shared use of tourniquets (24% versus 12%, P=0.01), spoons (43% versus 32%, P=0.09), filters (22% versus 15%, P=0.1), or drug mix (16% versus 9%, P=0.1), and difficulty finding a vein (73% versus 26%, P<0.001). Conclusion: The risk profile of IDUs (Injecting Drug Users) recruited at various sites provides important information for behavioural surveillance and health promotion efforts. Increased convenience of needle syringe access enhances HIV prevention efforts, however, appropriate education is required for people obtaining needle syringes at pharmacies to reduce sharing of injecting equipment other than needle syringes.
SN  - 0955-3959
AD  - National Centre in HIV Epidemiology and Clinical Research Level 2, 376 Victoria Street, Darlinghurst, NSW 2010, Australia; rthein@nchecr.unsw.edu.au
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ER  - 

TY  - JOUR
ID  - 104391315
T1  - Innovative Teaching Strategy for Pharmacology in Psychiatric-Mental Health Nursing: Moving from Content to Concepts.
AU  - Joy F. Bonnivier
AU  - April L. Magoteaux
Y1  - 2012/12//
N1  - Accession Number: 104391315. Language: English. Entry Date: 20130118. Revision Date: 20150818. Publication Type: Journal Article; CEU; pictorial; tables/charts. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Special Interest: Psychiatry/Psychology. NLM UID: 8200911. 
KW  - Mental Disorders -- Drug Therapy
KW  - Pharmacy and Pharmacology -- Education
KW  - Psychiatric Nursing -- Education
KW  - Psychotropic Drugs -- Therapeutic Use
KW  - Teaching Methods
KW  - Antianxiety Agents -- Adverse Effects
KW  - Antianxiety Agents -- Therapeutic Use
KW  - Antianxiety Agents, Benzodiazepine -- Adverse Effects
KW  - Antianxiety Agents, Benzodiazepine -- Therapeutic Use
KW  - Anticonvulsants -- Adverse Effects
KW  - Anticonvulsants -- Therapeutic Use
KW  - Antidepressive Agents -- Adverse Effects
KW  - Antidepressive Agents -- Therapeutic Use
KW  - Antipsychotic Agents -- Adverse Effects
KW  - Antipsychotic Agents -- Therapeutic Use
KW  - Anxiety Disorders
KW  - Attention Deficit Hyperactivity Disorder -- Drug Therapy
KW  - Central Nervous System Stimulants -- Adverse Effects
KW  - Central Nervous System Stimulants -- Therapeutic Use
KW  - Course Content
KW  - Curriculum
KW  - Depression -- Drug Therapy
KW  - Education, Continuing (Credit)
KW  - Narcotic Antagonists -- Adverse Effects
KW  - Narcotic Antagonists -- Therapeutic Use
KW  - Outcomes of Education
KW  - Psychotic Disorders -- Drug Therapy
KW  - Psychotropic Drugs -- Adverse Effects
KW  - Students, Undergraduate
KW  - Substance Use Disorders -- Drug Therapy
SP  - 22
EP  - 29 8p
JO  - Journal of Psychosocial Nursing & Mental Health Services
JF  - Journal of Psychosocial Nursing & Mental Health Services
JA  - J PSYCHOSOC NURS MENT HEALTH SERV
VL  - 50
IS  - 12
CY  - Thorofare, New Jersey
PB  - SLACK Incorporated
AB  - Faculty teaching an undergraduate psychiatric-mental health nursing course noted that the vast content related to psychotropic medication interventions needed to be conceptualized creatively to help students develop expertise. In this article, an innovative pedagogical approach is presented for teaching nursing students psychopharmacology by moving from content to concepts
SN  - 0279-3695
AD  - 3452 Fishinger Mill Drive, Hilliard, OH 43026; e-mail: cobjfb@columbus.rr.com.
U2  - PMID: 23457714.
DO  - 10.3928/02793695-20121107-03
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104391315&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103926689
T1  - Inside Maine’s Medicine Cabinet: Findings From the Drug Enforcement Administration’s Medication Take-Back Events.
AU  - Stewart, Heather
AU  - Malinowski, Alexandra
AU  - Ochs, Leslie
AU  - Jaramillo, Jeanie
AU  - McCall III, Kenneth
AU  - Sullivan, Meghan
Y1  - 2015/01//
N1  - Accession Number: 103926689. Language: English. Entry Date: 20141219. Revision Date: 20150710. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Core Nursing; Double Blind Peer Reviewed; Nursing; Peer Reviewed; Public Health; USA. Special Interest: Public Health. NLM UID: 1254074. 
KW  - Drug Enforcement Administration
KW  - Substance Abuse
KW  - Collection Development
KW  - Human
KW  - Maine
KW  - Multicenter Studies
KW  - Outcomes Research
KW  - Drugs -- Classification
SP  - e65
EP  - 71 1p
JO  - American Journal of Public Health
JF  - American Journal of Public Health
JA  - AM J PUBLIC HEALTH
VL  - 105
IS  - 1
CY  - Washington, District of Columbia
PB  - American Public Health Association
AB  - Objectives. We evaluated the quantity and type of medications obtained in unused-medications return programs and the proportion of medication waste. Methods. We analyzed data collected in 11 Maine cities in 2011 to 2013 during 6 Drug Enforcement Administration (DEA) national medication take-back events. Pharmacy doctoral student volunteers collected data under the supervision of law enforcement, independent of the DEA. Data entry into the Pharmaceutical Collection Monitoring System, through its interface with Micromedex, allowed for analysis of medication classification, controlled substance category, therapeutic class, and percentage of medication waste (units returned/units dispensed). Results. Medication take-back events resulted in return of 13 599 individual medications from 1049 participants. We cataloged 553 019 units (capsules, tablets, milliliters, patches, or grams), representing 69.7% medication waste. Noncontrolled prescription medications accounted for 56.4% of returns, followed by over-the- counter medications (31.4%) and controlled prescription medications (9.1%). Conclusions. The significant quantities of medications, including controlled substances, returned and high degree of medication waste emphasize the need for medication collection programs to further public health research and improve health in our communities.
SN  - 0090-0036
AD  - Department of Pharmacy Practice, College of Pharmacy, University of New England, Portland, ME
AD  - Medication Cleanout, Texas Panhandle Poison Center, Amarillo
DO  - 10.2105/AJPH.2014.302207
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103926689&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106920406
T1  - Integrating pharmacotherapy and psychosocial interventions in the treatment of individuals with alcohol problems...Summit on Social Work and the Neurobiology of Addictions hosted by the School of Social Work at the University of Texas at Austin on June 11-13, 2000
AU  - Zweben A
Y1  - 2001/09//
N1  - Accession Number: 106920406. Language: English. Entry Date: 20020503. Revision Date: 20150819. Publication Type: Journal Article; clinical trial; research; tables/charts. Journal Subset: Allied Health; Peer Reviewed; USA. NLM UID: 100898201. 
KW  - Alcoholism -- Therapy
KW  - Alcoholism -- Drug Therapy
KW  - Psychotherapy -- Methods
KW  - Combined Modality Therapy
KW  - Treatment Outcomes
KW  - Clinical Trials
KW  - Motivation
KW  - Self-Efficacy
KW  - Patient Compliance
KW  - Cognitive Therapy
KW  - Counseling
KW  - Wisconsin
KW  - Colleges and Universities -- Wisconsin
KW  - Social Work
KW  - Human
SP  - 65
EP  - 80 16p
JO  - Journal of Social Work Practice in the Addictions
JF  - Journal of Social Work Practice in the Addictions
JA  - J SOC WORK PRACT ADDICT
VL  - 1
IS  - 3
PB  - Taylor & Francis Ltd
AB  - Both research and clinical experiences suggest that there are separate and overlapping benefits of medications and psychosocial treatments for alcohol problems. Evidence has shown that medication(s) combined with a moderate intensity psychosocial therapy can produce outcomes beyond what each of these approaches can produce alone. Taking medication can be helpful in facilitating longer periods of abstinence that in turn affords practitioners a greater opportunity to enhance patients' individual and social coping resources and to increase their motivation to change. Combining effective pharmacological and psychosocial interventions may provide the impetus to integrate alcoholism treatment into the general health care delivery system, thereby helping to increase the accessibility of care and well-being for individuals seeking or needing help with alcohol problems.
SN  - 1533-256X
AD  - Professor and Director, Center for Addiction and Behavioral Health Research, School of Social Welfare, University of Wisconsin-Milwaukee, P.O. Box 786, Milwaukee, WI 53201
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 113883518
T1  - Integrating smoking cessation into routine care in hospitals--a randomized controlled trial.
AU  - Thomas, D.
AU  - Abramson, M. J.
AU  - Bonevski, B.
AU  - Taylor, S.
AU  - Poole, S. G.
AU  - Paul, E.
AU  - Weeks, G. R.
AU  - Dooley, M. J.
AU  - George, J.
Y1  - 2016/04//
N1  - Accession Number: 113883518. Language: English. Entry Date: 20160331. Revision Date: 20160331. Publication Type: Article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Instrumentation: Self-Efficacy Scale (SES); Short Form 8 Health Survey (SF-8); Charlson Comorbidity Index (CCI); Heaviness of Smoking Index (HSI); Patient Health Questionnaire (PHQ). Grant Information: Support provided by a Cancer Institute NSW Career Development Fellowship. This work was supported by the Australian Research Council through the Linkage Scheme (LP110200724) with The Alfred, Austin Health and Barwon Health as partner organizations, and an investigator-initiated research (IIR) grant from Pfizer.. NLM UID: 9304118. 
KW  - Smoking Cessation
KW  - Inpatients
KW  - Smoking -- Drug Therapy
KW  - Hospital Programs
KW  - Pharmacists -- Manpower
KW  - Randomized Controlled Trials
KW  - Hospitals, Public -- Australia
KW  - Multicenter Studies
KW  - Australia
KW  - Human
KW  - Female
KW  - Male
KW  - Adult
KW  - Middle Age
KW  - Descriptive Statistics
KW  - Data Analysis Software
KW  - P-Value
KW  - Confidence Intervals
KW  - Odds Ratio
KW  - Single-Blind Studies
KW  - Scales
KW  - Smoking Cessation -- Education
KW  - Pharmacists -- Education
KW  - Patient Education
KW  - Drug Therapy -- Education
KW  - Support, Psychosocial
KW  - Self-Efficacy
KW  - Questionnaires
KW  - Logistic Regression
KW  - Aged
KW  - Socioeconomic Factors
KW  - Carbon Monoxide -- Blood
KW  - Pretest-Posttest Design
KW  - Funding Source
SP  - 714
EP  - 723 10p
JO  - Addiction
JF  - Addiction
JA  - ADDICTION
VL  - 111
IS  - 4
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 0965-2140
AD  - Centre for Medicine Use and Safety, Monash University, Melbourne, Victoria Australia
AD  - Department of Epidemiology and Preventive Medicine, Monash University, Alfred, Melbourne, Victoria Australia
AD  - School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales Australia
AD  - Pharmacy Department, Austin Health, Melbourne, Victoria Australia
AD  - Pharmacy Department, Alfred Health, Melbourne, Victoria Australia
AD  - Clinical Haematology Department, Alfred, Melbourne, Victoria Australia
AD  - Pharmacy Department, Barwon Health, Geelong, Victoria Australia
DO  - 10.1111/add.13239
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106346308
T1  - Intensive community pharmacy intervention had little impact on triptan consumption: a randomized controlled trial.
AU  - Søndergaard J
AU  - Foged A
AU  - Kragstrup J
AU  - Gaist D
AU  - Gram LF
AU  - Sindrup SH
AU  - De Muckadell HUS
AU  - Larsen BO
AU  - Herborg H
AU  - Andersen M
Y1  - 2006/03//
N1  - Accession Number: 106346308. Language: English. Entry Date: 20061013. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts; randomized controlled trial. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. Grant Information: Danish Pharmacy Foundation. NLM UID: 8510679. 
KW  - Headache -- Drug Therapy
KW  - Serotonin Agonists -- Administration and Dosage
KW  - Sumatriptan -- Administration and Dosage
KW  - Vasoconstrictor Agents -- Administration and Dosage
KW  - Adult
KW  - Randomized Controlled Trials
KW  - Confidence Intervals
KW  - Data Analysis Software
KW  - Data Analysis, Statistical
KW  - Denmark
KW  - Descriptive Statistics
KW  - Education, Pharmacy
KW  - Female
KW  - Funding Source
KW  - Male
KW  - Medication Compliance
KW  - Middle Age
KW  - Migraine -- Drug Therapy
KW  - P-Value
KW  - Patient Education
KW  - Pharmacists
KW  - Pharmacy, Retail
KW  - Professional-Patient Relations
KW  - Questionnaires
KW  - Regression
KW  - Serotonin Agonists -- Adverse Effects
KW  - Sumatriptan -- Adverse Effects
KW  - Vasoconstrictor Agents -- Adverse Effects
KW  - Human
SP  - 16
EP  - 21 6p
JO  - Scandinavian Journal of Primary Health Care
JF  - Scandinavian Journal of Primary Health Care
JA  - SCAND J PRIM HEALTH CARE
VL  - 24
IS  - 1
CY  - Philadelphia, Pennsylvania
PB  - Taylor & Francis Ltd
AB  - OBJECTIVE: To evaluate the impact of an intensive pharmaceutical care campaign targeting inappropriate use of triptans. DESIGN: Randomized controlled trial. SETTING: 22 community pharmacies in the County of Funen, Denmark. SUBJECTS: A total of 1123 triptan users at intervention pharmacies and 1340 at control pharmacies. INTERVENTION: Intervention pharmacy staff received information on migraine and other types of headache, detection of inappropriate triptan use and other drug-related problems, and techniques for establishing a dialogue with patients. Intervention consisted of a folder and a structured dialogue with the pharmacy staff. The folder included questions aimed at detecting overuse and inappropriate triptan use. MAIN OUTCOME MEASURES: Change in average triptan consumption in doses per month measured by means of a prescription database with information on all purchases of reimbursed drugs at the level of the individual patient. RESULTS: Overall, intervention had no statistically significant short-term impact on patients' consumption of triptans either among incident users (intervention/control ratio 1.02; 95% confidence interval 0.95 to 1.12), or among prevalent users (1.02; 0.97 to 1.08). No effects were observed after 6 and 9 months, apart from a possible borderline effect after 9 months among prevalent users with intermediate triptan consumption (0.93; 0.87 to 1.00). CONCLUSION: The pharmaceutical care campaign did not reduce the use of triptans.
SN  - 0281-3432
AD  - Research Unit for General Practice, University of Aarhus, Aarhus
U2  - PMID: 16464810.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106538541
T1  - Interdisciplinary medication education in a church environment.
AU  - Schommer JC
AU  - Byers SR
AU  - Pape LL
AU  - Cable GL
AU  - Worley MM
AU  - Sherrin T
Y1  - 2002/03//3/1/2002
N1  - Accession Number: 106538541. Language: English. Entry Date: 20081219. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. Grant Information: ASHP Research and Education Foundation and Pfizer Corporation. NLM UID: 9503023. 
KW  - Patient Education -- Methods
KW  - Drug Therapy -- Education
KW  - Learning Environment
KW  - Churches
KW  - Ohio
KW  - Pharmacists
KW  - Interns and Residents
KW  - Nurses
KW  - Exit Interviews
KW  - Patient Attitudes -- Evaluation
KW  - Prospective Studies
KW  - Statistical Significance
KW  - Collaboration
KW  - Program Implementation
KW  - Program Evaluation
KW  - Descriptive Statistics
KW  - Parish Nursing
KW  - Coding
KW  - Chi Square Test
KW  - Paired T-Tests
KW  - Adult
KW  - Middle Age
KW  - Aged
KW  - Aged, 80 and Over
KW  - Male
KW  - Female
KW  - Funding Source
KW  - Human
SP  - 423
EP  - 428 6p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 59
IS  - 5
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
AB  - A medication education program for ambulatory care patients implemented in a church setting was studied. The program at each of 20 churches in Ohio consisted of a one-hour orientation for pharmacists/interns, a 20-minute presentation on medications and health, a question-and-answer session led by a pharmacist and a nurse, a one-on-one session with a pharmacist, and an exit interview with a nurse. Before the program, patients completed a form to assess their current experiences with medications and their interactions with health care professionals in the preceding six months. During an exit interview at the end of the program, patients were asked whether the program has been understandable and beneficial and whether taking medications affected their lifestyle. A follow-up interview was conducted six months later. A total of 187 patients completed both the exit and follow-up interviews. Almost all reported that the church setting was a good place for the program and that the program was beneficial. During the six months after the program, the patients took significantly fewer drugs each day than during the six months before the program and had fewer drug-related problems. Significantly more patients sought drug information after completing the program than before it. High rates of medication misuse were identified, leading to 359 pharmacist recommendations. An interdisciplinary program in a church setting successfully provided medication education.
SN  - 1079-2082
AD  - College of Pharmacy, University of Minnesota, 308 Harvard Street, S.E., Minneapolis, MN 55455; schom010@tc.umn.edu
U2  - PMID: 11887408.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103901390
T1  - Interprofessional socialization as a way to introduce collaborative competencies to first-year health science students.
AU  - DiVall, Margarita V
AU  - Kolbig, Leslie
AU  - Carney, Mary
AU  - Kirwin, Jennifer
AU  - Letzeiser, Christine
AU  - Mohammed, Shan
Y1  - 2014/11//
N1  - Accession Number: 103901390. Language: English. Entry Date: 20141015. Revision Date: 20150710. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Core Nursing; Double Blind Peer Reviewed; Europe; Nursing; Peer Reviewed; UK & Ireland. Instrumentation: Readiness for Interprofessional Learning Scale (RIPLS). NLM UID: 9205811. 
KW  - Collaboration
KW  - Learning Methods
KW  - Students, Medical -- Massachusetts
KW  - Substance Abuse
KW  - Alcohol Drinking
KW  - Congresses and Conferences -- Massachusetts
KW  - Interprofessional Relations
KW  - Socialization
KW  - Curriculum
KW  - Massachusetts
KW  - Professional Role
KW  - Students, Nursing -- Massachusetts
KW  - Wilcoxon Rank Sum Test
KW  - Students, Pharmacy
KW  - Students, Speech-Language Pathology
KW  - Students, Audiology
KW  - Psychological Tests
SP  - 576
EP  - 578 3p
JO  - Journal of Interprofessional Care
JF  - Journal of Interprofessional Care
JA  - J INTERPROF CARE
VL  - 28
IS  - 6
CY  - Philadelphia, Pennsylvania
PB  - Taylor & Francis Ltd
AB  - Interprofessional education (IPE) is the cornerstone of preparing future health care providers but remains to be a challenge for many health science programs. We aimed to develop and evaluate an interprofessional conference for first-year health science students with goals to provide students with interprofessional socialization opportunity and introduce IPE principles. A half-day conference was based upon core competencies for health professionals and involved 277 first-year health sciences, nursing, pharmacy, physical therapy, and speech language pathology and audiology students. Alcohol and substance misuse was chosen as a topic for its relevance to college students and health professionals. Results from program evaluation revealed that the conference was successful in exposing students to core interprofessional competencies and provided useful information about alcohol and substance misuse. This study advocates for early inclusion of IPE in the health professions curricula in the form of interprofessional socialization.
SN  - 1356-1820
U2  - PMID: 24828617.
DO  - 10.3109/13561820.2014.917403
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105480416
T1  - Interventions for preventing weight gain after smoking cessation.
AU  - Farley AC
AU  - Hajek P
AU  - Lycett D
AU  - Aveyard P
Y1  - 2012/01//
N1  - Accession Number: 105480416. Language: English. Entry Date: 20091023. Revision Date: 20150711. Publication Type: Journal Article; research; systematic review. Journal Subset: Europe; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice. NLM UID: 100909747. Cochrane AN: CD006219. 
KW  - Smoking Cessation
KW  - Weight Gain -- Prevention and Control
KW  - Behavior Therapy
KW  - Bupropion
KW  - Clinical Trials
KW  - Exercise
KW  - Fluoxetine
KW  - Naltrexone
KW  - Nicotine Replacement Therapy
KW  - Outcomes (Health Care)
KW  - Phenylpropanolamine
KW  - Relative Risk
KW  - Human
SP  - N.PAG
EP  - N.PAG 1p
JO  - Cochrane Database of Systematic Reviews
JF  - Cochrane Database of Systematic Reviews
JA  - COCHRANE DATABASE SYST REV
IS  - 1
CY  - , <Blank>
PB  - John Wiley & Sons, Inc.
AB  - Most people who stop smoking gain weight. There are some interventions that have been designed to reduce weight gain when stopping smoking. Some smoking cessation interventions may also limit weight gain although their effect on weight has not been reviewed. To systematically review the effect of: (1) Interventions targeting post-cessation weight gain on weight change and smoking cessation.(2) Interventions designed to aid smoking cessation that may also plausibly affect weight on post-cessation weight change. Part 1 - We searched the Cochrane Tobacco Addiction Group's Specialized Register and CENTRAL in September 2011.Part 2 - In addition we searched the included studies in the following 'parent' Cochrane reviews: nicotine replacement therapy (NRT), antidepressants, nicotine receptor partial agonists, cannabinoid type 1 receptor antagonists and exercise interventions for smoking cessation published in Issue 9, 2011 of the Cochrane Library. Part 1 - We included trials of interventions that were targeted at post-cessation weight gain and had measured weight at any follow up point and/or smoking cessation six or more months after quit day.Part 2 - We included trials that had been included in the selected parent Cochrane reviews if they had reported weight gain at any time point. We extracted data on baseline characteristics of the study population, intervention, outcome and study quality. Change in weight was expressed as difference in weight change from baseline to follow up between trial arms and was reported in abstinent smokers only. Abstinence from smoking was expressed as a risk ratio (RR). We used the most rigorous definition of abstinence available in each trial. Where appropriate, we performed meta-analysis using the inverse variance method for weight and Mantel-Haenszel method for smoking using a fixed-effect model. Part 1: Some pharmacological interventions tested for limiting post cessation weight gain (PCWG) resulted in a significant reduction in WG at the end of treatment (dexfenfluramine (Mean difference (MD) -2.50âkg, 95% confidence interval (CI) -2.98 to -2.02, 1 study), phenylpropanolamine (MD -0.50âkg, 95% CIâ-0.80 to -0.20, N=3), naltrexone (MD -0.78âkg, 95% CIâ -1.52 to -0.05, N=2). There was no evidence that treatment reduced weight at 6 or 12 months (m). No pharmacological intervention significantly affected smoking cessation rates.Weight management education only was associated with no reduction in PCWG at end of treatment (6 or 12m). However these interventions significantly reduced abstinence at 12m (Risk ratio (RR) 0.66, 95% CI 0.48 to 0.90, N=2). Personalised weight management support reduced PCWG at 12m (MD -2.58âkg, 95% CI -5.11 toâ-0.05, N=2) and was not associated with a significant reduction of abstinence at 12m (RR 0.74, 95% CI 0.39 to 1.43, N=2). A very low calorie diet (VLCD) significantly reduced PCWG at end of treatment (MD -3.70âkg, 95% CIâ-4.82 toâ-2.58, N=1), but not significantly so at 12m (MD -1.30âkg, 95% CIâ-3.49 to 0.89, N=1). The VLCD increased chances of abstinence at 12m (RR 1.73, 95% CI 1.10 to 2.73, N=1). There was no evidence that cognitive behavioural therapy to allay concern about weight gain (CBT) reduced PCWG, but there was some evidence of increased PCWG at 6m (MD 0.74, 95% CI 0.24 to 1.24). It was associated with improved abstinence at 6m (RR 1.83, 95% CI 1.07 to 3.13, N=2) but not at 12m (RR 1.25, 95% CI 0.83 to 1.86, N=2). However, there was significant statistical heterogeneity.Part 2: We found no evidence that exercise interventions significantly reduced PCWG at end of treatment (MD -0.25âkg, 95% CIâ-0.78 to 0.29, N=4) however a significant reduction was found at 12m (MD -2.07âkg, 95% CIâ-3.78 toâ-0.36, N=3).Both bupropion and fluoxetine limited PCWG at the end of treatment (bupropion MD -1.12âkg, 95% CIâ-1.47 toâ-0.77, N=7) (fluoxetine MD -0.99âkg, 95% CIâ-1.36 toâ-0.61, N=2). There was no evidence that the effect persisted at 6m (bupropion MD -0.58â kg, 95% CIâ-2.16 to 1.00, N=4), (fluoxetine MD -0.01âkg, 95% CIâ-1.11 to 1.10, N=2) or 12m (bupropion MD -0.38âkg, 95% CIâ-2.00 to 1.24, N=4). There were no data on WG at 12m for fluoxetine.Overall, treatment with NRT attenuated PCWG at the end of treatment (MD -0.69âkg, 95% CIâ-0.88 toâ-0.51, N=19), with no strong evidence that the effect differed for the different forms of NRT. There was evidence of significant statistical heterogeneity caused by one study which reported a 4.3âkg reduction in PCWG due to NRT. With this study removed, the difference in weight change at end of treatment was -0.45â kg (95% CIâ-0.66 toâ-0.27, N=18). There was no evidence of an effect on PCWG at 12m (MD -0.42âkg, 95% CIâ-0.92 to 0.08, N=15).We found evidence that varenicline significantly reduced PCWG at end of treatment (MD -0.41âkg, 95% CIâ-0.63 toâ-0.19, N=11), but this effect was not maintained at 6 or 12m. Three studies compared the effect of bupropion to varenicline. Participants taking bupropion gained significantly less weight at the end of treatment (-0.51âkg (95% CIâ-0.93 toâ-0.09âkg), N=3). Direct comparison showed no significant difference in PCWG between varenicline and NRT. Although some pharmacotherapies tested to limit PCWG show evidence of short-term success, other problems with them and the lack of data on long-term efficacy limits their use. Weight management education only, is not effective and may reduce abstinence. Personalised weight management support may be effective and not reduce abstinence, but there are too few data to be sure. One study showed a VLCD increased abstinence but did not prevent WG in the longer term. CBT to accept WG did not limit PCWG and may not promote abstinence in the long term. Exercise interventions significantly reduced weight in the long term, but not the short term. More studies are needed to clarify whether this is an effect of treatment or a chance finding. Bupropion, fluoxetine, NRT and varenicline reduce PCWG while using the medication. Although this effect was not maintained one year after stopping smoking, the evidence is insufficient to exclude a modest long-term effect. The data are not sufficient to make strong clinical recommendations for effective programmes to prevent weight gain after cessation.[CINAHL Note: The Cochrane Collaboration systematic reviews contain interactive software that allows various calculations in the MetaView.]
SN  - 1469-493X
U2  - PMID: 22258966.
DO  - 10.1002/14651858.CD006219.pub2
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106702846
T1  - Investigation into the reasons for preventable drug related admissions to a medical admissions unit: observational study.
AU  - Howard RL
AU  - Avery AJ
AU  - Howard PD
AU  - Partridge M
Y1  - 2003/08//
N1  - Accession Number: 106702846. Language: English. Entry Date: 20040213. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Blind Peer Reviewed; Europe; Expert Peer Reviewed; Health Services Administration; Peer Reviewed; UK & Ireland. Grant Information: Partially funded by Wyeth Laboratories and NHS R&D. NLM UID: 101136980. 
KW  - Hospitalization
KW  - Medication Compliance
KW  - Medication Errors
KW  - Morbidity -- Etiology
KW  - Chi Square Test
KW  - Correlation Coefficient
KW  - Data Analysis Software
KW  - Descriptive Statistics
KW  - Female
KW  - Interrater Reliability
KW  - Interviews
KW  - Kappa Statistic
KW  - Male
KW  - Nonexperimental Studies
KW  - Pilot Studies
KW  - United Kingdom
KW  - Funding Source
KW  - Human
SP  - 280
EP  - 285 6p
JO  - Quality & Safety in Health Care
JF  - Quality & Safety in Health Care
JA  - QUAL SAF HEALTH CARE
PB  - BMJ Publishing Group
AB  - OBJECTIVE: To describe the drugs and types of medicine management problems most frequently associated with preventable drug related admissions to an acute medical admissions unit. DESIGN: Observation study. SETTING: Medical admissions unit in a teaching hospital in Nottingham, UK. PARTICIPANTS: 4093 patients seen by pharmacists on the medical admissions unit between 1 January and 30 June 2001. MAIN OUTCOME MEASURES: Proportion of admissions that were drug related and preventable, classification of the underlying causes of preventable drug related admissions, and identification of drugs most commonly associated with preventable drug related admissions. RESULTS: Of the admissions seen by pharmacists, 265 (6.5%) were judged to be drug related and 178 (67%) of these were judged to be preventable. Preventable admissions were mainly due to problems with prescribing (63 cases (35%)), monitoring (46 cases (26%)), and adherence to medication (53 cases (30%)). The drugs most commonly implicated were NSAIDs, antiplatelets, antiepileptics, hypoglycaemics, diuretics, inhaled corticosteroids, cardiac glycosides, and beta-blockers. CONCLUSIONS: Potentially preventable drug related morbidity was associated with 4.3% of admissions to a medical admissions unit. In 91% of cases these admissions were related to problems with either prescribing, monitoring, or adherence.
SN  - 1475-3898
AD  - Division of Primary Care, School of Community Health Sciences, University Hospital, Nottingham NG7 2UH, UK; Rachel.howard@@broxtowehucknall-pct.nhs.uk
U2  - PMID: 12897361.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106702846&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106011320
T1  - Is attributing smoking to genetic causes associated with a reduced probability of quit attempt success? A cohort study.
AU  - Wright AJ
AU  - Aveyard P
AU  - Guo B
AU  - Murphy M
AU  - Brown K
AU  - Marteau TM
Y1  - 2007/10//
N1  - Accession Number: 106011320. Language: English. Entry Date: 20080229. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology. NLM UID: 9304118. 
KW  - Disease Susceptibility -- Classification
KW  - Smoking
KW  - Smoking Cessation
KW  - Adult
KW  - Female
KW  - Great Britain
KW  - Health Promotion
KW  - Male
KW  - Prospective Studies
KW  - Smoking -- Epidemiology
KW  - Human
SP  - 1657
EP  - 1664 8p
JO  - Addiction
JF  - Addiction
JA  - ADDICTION
VL  - 102
IS  - 10
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - AIMS: Pharmacogenetic smoking cessation interventions would involve smokers being given information about the influence of genes on their behaviour. However, attributing smoking to genetic causes may reduce perceived control over smoking, reducing quit attempt success. This study examines whether attributing smoking to genetic influences is associated with reduced quitting and whether this effect is mediated by perceived control over smoking. DESIGN: Cohort study. PARTICIPANTS: A total of 792 smokers, participating in a trial of nicotine replacement therapy (NRT)-assisted smoking cessation. Participants were informed that the trial investigated relationships between genetic markers and smoking behaviour, but personalized genetic feedback was not provided. SETTING: Primary care in Oxfordshire and Buckinghamshire, UK. MEASUREMENTS: Perceived control over smoking and perceived importance of genetic factors in causing smoking assessed pre-quit; abstinence 4, 12, 26 and 52 weeks after the start of treatment. FINDINGS: A total of 515 smokers (65.0%) viewed genetic factors as playing some role in causing their smoking. They had lower perceived control over smoking than smokers who viewed genetic factors as having no role in causing their smoking. Attributing smoking to genetic causes was not associated significantly with a lower probability of quit attempt success. CONCLUSIONS: Attributing smoking to genetic factors was associated with lower levels of perceived control over smoking but not lower quit rates. This suggests that learning of one's genetic predisposition to smoking during a pharmacogenetically tailored smoking cessation intervention may not deter quitting. Further research should examine whether the lack of impact of genetic attributions on quit attempt success is also found in smokers provided with personalized genetic feedback.
SN  - 0965-2140
U2  - PMID: 17854342.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106011320&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 113666783
T1  - Is treatment for alcohol use disorder associated with reductions in criminal offending? A national data linkage cohort study in England.
AU  - Willey, Helen
AU  - Eastwood, Brian
AU  - Gee, Ivan L.
AU  - Marsden, John
Y1  - 2016/04//
N1  - Accession Number: 113666783. Language: English. Entry Date: In Process. Revision Date: 20160317. Publication Type: journal article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 7513587. 
SP  - 67
EP  - 76 10p
JO  - Drug & Alcohol Dependence
JF  - Drug & Alcohol Dependence
JA  - DRUG ALCOHOL DEPENDENCE
VL  - 161
PB  - Elsevier Science
AB  - Background: This is the first English national study of change in criminal offending following treatment for alcohol use disorder (AUD).Methods: All adults treated for AUD by all publicly funded treatment services during April 2008-March 2009 (n=53,017), with data linked to the Police National Computer (April 2006-November 2011). Pre-treatment offender sub-populations were identified by Latent Profile Analysis. The outcome measure was the count of recordable criminal offences during two-year follow-up after admission. A mixed-effects, Poisson regression modelled outcome, adjusting for demographics and clinical information, the latent classes, and treatment exposure covariates.Results: Twenty-two percent of the cohort committed one or more offences in the two years pre-treatment (n=11,742; crude rate, 221.5 offenders per 1000). During follow-up, the number of offenders and offences fell by 23.5% and 24.0%, respectively (crude rate, 69.4 offenders per 1000). During follow-up, a lower number of offences was associated with: completing treatment (adjusted incident rate ratio [IRR] 0.82; 95% confidence interval [CI] 0.79-0.85); receiving inpatient detoxification (IRR 0.84; CI 0.80-0.89); or community pharmacological therapy (IRR 0.89; CI 0.84-0.96). Reconviction was reduced in the sub-population characterised by driving offences (n=1,140; 11.7%), but was relatively high amongst acquisitive (n=768; 58.3% reconvicted) and violent offending sub-populations (n=602; 77.6% reconvicted).Conclusions: Reduced offending was associated with successful completion of AUD treatment and receiving inpatient and pharmacological therapy, but not enrolment in psychological and residential interventions. Treatment services (particularly those providing psychological therapy and residential care) should be alert to offending, especially violent and acquisitive crime, and enhance crime reduction interventions.
SN  - 0376-8716
AD  - Alcohol, Drug and Tobacco Division, Health and Wellbeing Directorate, Public Health England, United Kingdom
AD  - Institute of Psychiatry, Psychology and Neuroscience, King’s College London,United Kingdom
AD  - Centre for Public Health, Liverpool John Moores University, United Kingdom
U2  - PMID: 26861884.
DO  - 10.1016/j.drugalcdep.2016.01.020
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=113666783&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106842001
T1  - Lack of pharmacokinetic interaction between valproic acid and a traditional Chinese medicine, Paeoniae Radix, in healthy volunteers.
AU  - Chen LC
AU  - Chou MH
AU  - Lin MF
AU  - Yang LL
Y1  - 2000/12//
N1  - Accession Number: 106842001. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article; clinical trial; research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Grant Information: Supported by research grant VGH88-238 from Veterans General Hospital-Taipei. NLM UID: 8704308. 
KW  - Drug Interactions
KW  - Medicine, Chinese Traditional -- Adverse Effects
KW  - Valproic Acid -- Pharmacokinetics
KW  - Adult
KW  - Biological Availability
KW  - Clinical Trials
KW  - Crossover Design
KW  - Descriptive Statistics
KW  - Epilepsy -- Blood
KW  - Epilepsy -- Drug Therapy
KW  - Epilepsy -- Urine
KW  - Female
KW  - Immunoassay
KW  - Linear Regression
KW  - Male
KW  - Paired T-Tests
KW  - Random Assignment
KW  - Taiwan
KW  - Valproic Acid -- Blood
KW  - Funding Source
KW  - Human
SP  - 453
EP  - 459 7p
JO  - Journal of Clinical Pharmacy & Therapeutics
JF  - Journal of Clinical Pharmacy & Therapeutics
JA  - J CLIN PHARM THER
VL  - 25
IS  - 6
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - BACKGROUND AND OBJECTIVE: In addition to the standard antiepileptic drugs, traditional Chinese medicines (TCMs) are used for the treatment of epilepsy in oriental countries. The interactions between antiepileptic drugs and TCMs represent a potential problem in clinical application. Because valproic acid (VPA), one of the most widely prescribed antiepileptic drugs, may be administered concomitantly with Paeoniae Radix (PR), one of the famous TCMs, in some epileptic patients, the present study was conducted to evaluate the influences of PR on the pharmacokinetics of VPA. METHOD: The pharmacokinetics of VPA were investigated in a randomized, open-label, two-way crossover study. Six healthy volunteers received the following treatments in a crossover design: (i) 1.2 g extract powder of Paeoniae Radix once daily for 7 days and one 200 mg VPA gastro-resistant tablet on day 7 and (ii) one 200 mg VPA gastro-resistant tablet alone on day 7. Serial plasma samples were obtained on day 7. Total and free (unbound) VPA plasma concentrations were determined by fluorescence polarization immunoassay (FPIA). Safety measures included laboratory tests (haematology, serum chemistry and urinalysis) and adverse event monitoring. Statistical comparisons of pharmacokinetic parameters were performed with the Student paired t-test. RESULTS: Overall clinical safety was satisfactory. The mean maximum plasma concentration of VPA was attained at within 6 h after oral administration of VPA alone and 3-4 h after oral administration of VPA in combination with PR. The plasma level of VPA declined with a half-life of 11.71 and 11.91 h, respectively. No statistically significant difference was obtained in any of the pharmacokinetic parameters (Tmax, Cmax, AUC, t1/2, MRT, CL/F and Vd/F) of VPA between the two treatments. Also, there was no significant difference in the protein binding rates of VPA. CONCLUSION: PR did not significantly affect the absorption, distribution, metabolism and elimination of VPA in healthy volunteers.
SN  - 0269-4727
AD  - Department of Pharmacognosy, Graduate Institute of Pharmaceutical Sciences, Taipei Medical College
U2  - PMID: 11123499.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106842001&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106753919
T1  - Learning the language of abstinence in addiction treatment: some similarities between relapse-prevention with disulfiram, naltrexone, and other pharmacological antagonists and intensive 'immersion' methods of foreign language teaching.
AU  - Brewer C
AU  - Streel E
Y1  - 2003/09//
N1  - Accession Number: 106753919. Language: English. Entry Date: 20040709. Revision Date: 20150711. Publication Type: Journal Article; review; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 8808537. 
KW  - Disulfiram -- Therapeutic Use
KW  - Naltrexone -- Therapeutic Use
KW  - Recurrence -- Prevention and Control
KW  - Substance Abuse -- Therapy
KW  - Teaching Methods -- Utilization
KW  - Clinical Trials
KW  - Treatment Duration
SP  - 157
EP  - 173 17p
JO  - Substance Abuse
JF  - Substance Abuse
JA  - SUBST ABUSE
VL  - 24
IS  - 3
PB  - Taylor & Francis Ltd
AB  - Relapse-prevention (RP) is an educational process. Learning to abstain from alcohol or opiates after years of dependence involves selectively suppressing old, maladaptive habits of thought and behavior and establishing new, adaptive ones. This process resembles foreign language (FL) learning. Effective FL teaching techniques are relevant to RP. 'Immersion,' the most effective FL teaching method, discourages students from using their first language ab initio, requiring them to use the FL instead, however inexpertly. It resembles exposure and response-prevention for phobic or compulsive disorders. Supervised disulfiram aids RP by discouraging alcoholics from responding to real-life drinking cues in the 'language' of excessive drinking, requiring them, ab initio, to practice new, alcohol-free responses. Supervised or depot naltrexone acts similarly in opiate dependence. We discuss the concept of antagonist-assisted abstinence.
SN  - 0889-7077
AD  - Stepleford Centre, 25a Eccleston St, London SW1W 9NP, UK; cbrewer@doctors.net.uk
U2  - PMID: 12913365.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106753919&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104043445
T1  - Life context of pharmacological academic performance enhancement among university students - a qualitative approach.
AU  - Hildt, Elisabeth
AU  - Lieb, Klaus
AU  - Franke, Andreas Günter
Y1  - 2014/01//
N1  - Accession Number: 104043445. Language: English. Entry Date: 20141114. Revision Date: 20150710. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; UK & Ireland. NLM UID: 101088680. 
KW  - Amphetamines -- Administration and Dosage
KW  - Central Nervous System Stimulants -- Administration and Dosage
KW  - Methylphenidate -- Administration and Dosage
KW  - Nootropic Agents -- Administration and Dosage
KW  - Students -- Psychosocial Factors
KW  - Substance Use Disorders -- Epidemiology
KW  - Colleges and Universities
KW  - Adult
KW  - Cognition -- Drug Effects
KW  - Educational Status
KW  - Female
KW  - Human
KW  - Male
KW  - Motivation
KW  - Qualitative Studies
KW  - Substance Use Disorders -- Psychosocial Factors
SP  - 23
EP  - 23 1p
JO  - BMC Medical Ethics
JF  - BMC Medical Ethics
JA  - BMC MED ETHICS
VL  - 15
IS  - 1
PB  - BioMed Central
SN  - 1472-6939
AD  - Department of Philosophy, Johannes Gutenberg University of Mainz, Jakob Welder-Weg 18, D - 55099 Mainz, Germany. hildt@uni-mainz.de.
U2  - PMID: 24606831.
DO  - 10.1186/1472-6939-15-23
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104043445&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105351201
T1  - Long-term effects of a multifaceted intervention to encourage the choice of the oral route for proton pump inhibitors: an interrupted time-series analysis.
AU  - Colombet I
AU  - Sabatier B
AU  - Gillaizeau F
AU  - Prognon P
AU  - Begué D
AU  - Durieux P
Y1  - 2009/06//
N1  - Accession Number: 105351201. Language: English. Entry Date: 20090710. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Blind Peer Reviewed; Europe; Expert Peer Reviewed; Health Services Administration; Peer Reviewed; UK & Ireland. Special Interest: Patient Safety; Quality Assurance. NLM UID: 101136980. 
KW  - Administration, Oral
KW  - Prescribing Patterns -- Trends
KW  - Proton Pump Inhibitors -- Administration and Dosage
KW  - Treatment Outcomes
KW  - Academic Medical Centers -- France
KW  - Administration, Intravenous -- Economics
KW  - Audit
KW  - Confidence Intervals
KW  - Cost Savings
KW  - Feedback
KW  - France
KW  - Inpatients
KW  - Linear Regression
KW  - Multidisciplinary Care Team -- Education
KW  - Practice Guidelines -- Education
KW  - Time Series
KW  - Human
SP  - 232
EP  - 235 4p
JO  - Quality & Safety in Health Care
JF  - Quality & Safety in Health Care
JA  - QUAL SAF HEALTH CARE
VL  - 18
IS  - 3
PB  - BMJ Publishing Group
AB  - PROBLEM: Drugs are often given intravenously even when the patient is able to swallow and when an oral form would be more cost-effective. DESIGN: Evaluation of the impact of a multifaceted intervention on the early switch from intravenous to oral administration of proton pump inhibitors (PPI) in a hospital setting. The interrupted time series of intravenous PPI consumption was analysed. BACKGROUND AND SETTING: At a French University Hospital, the Drug Committee, composed of multidisciplinary pharmacy and medical staff, addressed the issue of increasing consumption of intravenous PPI drugs (May 2003). Strategy for change: Letters to department heads, academic analyses from members of the Drug Committee, paper reminders at the point of care and audit-feedbacks by pharmacists. Monitoring of consumption and repeated reminder letters were planned. EFFECT OF CHANGE: The consumption of PPI was stable before the first intervention (mean level: 954 units/month). An immediate decrease occurred after the first Drug Committee letter (30% relative reduction, 95% CI -16% to -46%; p<0.001) with a significant trend change during the first multifaceted intervention (-24 units/month, 95% CI -42 to -7; p = 0.007). After the end of the outreach visits (July 2004), the consumptions increased (+32 units/month, 95% CI: 14 to 50, p<0.001). The second intervention had no significant impact. LESSONS LEARNT: A complex intervention (audit, feedbacks, outreach visits) had an effect on practice. It was not sustained even after a less resource-intensive intervention. Other types of interventions are needed that could be continuously implemented to improve ordering practices long term.
SN  - 1475-3898
AD  - INSERM, UMR_S 872, Paris, France. isabelle.colombet@egp.aphp.fr
U2  - PMID: 19468008.
DO  - 10.1136/qshc.2007.023887
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105351201&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106191752
T1  - Long-term issues in the treatment of sleep disorders.
AU  - Roth T
AU  - Krystal AD
AU  - Lieberman JA III
A2  - Ginsberg DL
Y1  - 2007/07/02/2007 Jul Suppl 10
N1  - Accession Number: 106191752. Language: English. Entry Date: 20071116. Revision Date: 20150711. Publication Type: Journal Article; abstract; diagnostic images; questions and answers; tables/charts. Supplement Title: 2007 Jul Suppl 10. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Psychiatry/Psychology. NLM UID: 9702877. 
KW  - Insomnia -- Therapy
KW  - Antianxiety Agents, Benzodiazepine -- Pharmacokinetics
KW  - Antianxiety Agents, Benzodiazepine -- Therapeutic Use
KW  - Antidepressive Agents -- Therapeutic Use
KW  - Arousal
KW  - Behavior Therapy
KW  - Cognitive Therapy
KW  - Depression
KW  - Functional Assessment
KW  - Hypnotics and Sedatives -- Administration and Dosage
KW  - Hypnotics and Sedatives -- Therapeutic Use
KW  - Insomnia -- Complications
KW  - Insomnia -- Diagnosis
KW  - Insomnia -- Drug Therapy
KW  - Insomnia -- Epidemiology
KW  - Insomnia -- Etiology
KW  - Insomnia -- Risk Factors
KW  - Pain
KW  - Quality of Life
KW  - Sleep -- Methods
KW  - Treatment Duration
SP  - 1
EP  - 15 15p
JO  - CNS Spectrums: The International Journal of Neuropsychiatric Medicine
JF  - CNS Spectrums: The International Journal of Neuropsychiatric Medicine
JA  - CNS SPECTRUMS
VL  - 12
IS  - 7
CY  - New York, New York
PB  - MBL Communications
AB  - Insomnia is a disorder characterized by chronic sleep disturbance associated with daytime disability or distress, such as memory impairment and fatigue, that occurs despite adequate opportunity for sleep. Insomnia may present as difficulty falling/staying asleep or as sleep that is nonrestorative. Studies show a strong correlation between insomnia and impaired quality of life. Pain conditions and depression are commonly associated with insomnia, either as secondary or comorbid conditions. In addition, a greater incidence of anxiety, alcohol and drug dependence, and cardiovascular disease is found in people with insomnia. Data indicate insomnia results from over-engaged arousal systems. Insomnia patients experience increased metabolic rate, body temperature, and heart rate, and elevated levels of norepinephrine and catecholamines. Pharmacologic options for the treatment of insomnia include benzodiazepine hypnotics, a selective melatonin receptor agonist, and sedating antidepressants. However, insomnia may be best treated with cognitive-behavioral therapy and instruction in good sleep hygiene, either alone or in concert with pharmacologic agents. Studies on the effects of insomnia treatment use variable methodologies or do not publish negative results, and there are currently no studies of treatment focusing on morbidity. Further research is necessary to better understand the effects of insomnia therapies on medical and psychiatric disorders. In this Clinical Information Supplement, Thomas Roth, PhD, describes the nature of insomnia and its pathophysiology. Next, Andrew D. Krystal, MD, MS, reviews morbidities associated with insomnia. Finally, Joseph A. Lieberman III, MD, MPH, provides an overview of therapeutics utilized in patients with insomnia, including behavioral therapies and pharmacologic options.
SN  - 1092-8529
AD  - Director, Sleep Disorders and Research Center, Henry Ford Health System, Detroit
U2  - PMID: 17603408.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106191752&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105933175
T1  - Long-term issues in the treatment of sleep disorders.
AU  - Roth T
AU  - Krystal AD
AU  - Lieberman JA III
A2  - Ginsberg DL
Y1  - 2007/07//2007 Jul
N1  - Accession Number: 105933175. Language: English. Entry Date: 20080118. Revision Date: 20150711. Publication Type: Journal Article; diagnostic images; forms; questions and answers; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Psychiatry/Psychology. Grant Information: Takeda Pharmaceuticals North American. NLM UID: 9602353. 
KW  - Insomnia -- Therapy
KW  - Aged
KW  - Aged, 80 and Over
KW  - Antianxiety Agents, Benzodiazepine -- Administration and Dosage
KW  - Antianxiety Agents, Benzodiazepine -- Pharmacokinetics
KW  - Antidepressive Agents -- Therapeutic Use
KW  - Arousal
KW  - Behavior Therapy
KW  - Cardiovascular Risk Factors
KW  - Comorbidity
KW  - Female
KW  - Funding Source
KW  - Hypnotics and Sedatives -- Administration and Dosage
KW  - Hypnotics and Sedatives -- Pharmacokinetics
KW  - Insomnia -- Complications
KW  - Insomnia -- Diagnosis
KW  - Insomnia -- Epidemiology
KW  - Insomnia -- Etiology
KW  - Insomnia -- Physiopathology
KW  - Insomnia -- Psychosocial Factors
KW  - Insomnia -- Risk Factors
KW  - Male
KW  - Mental Health
KW  - Middle Age
KW  - Pain
KW  - Quality of Life
KW  - Sleep -- Standards
KW  - Treatment Duration
SP  - 14p
EP  - 14p 1p
JO  - Primary Psychiatry
JF  - Primary Psychiatry
JA  - PRIM PSYCHIATRY
VL  - 14
IS  - 7
CY  - New York, New York
PB  - MBL Communications
AB  - Insomnia is a disorder characterized by chronic sleep disturbance associated with daytime disability or distress, such as memory impairment and fatigue, that occurs despite adequate opportunity for sleep. Insomnia may present as difficulty falling/staying asleep or as sleep that is nonrestorative. Studies show a strong correlation between insomnia and impaired quality of life. Pain conditions and depression are commonly associated with insomnia, either as secondary or comorbid conditions. In addition, a greater incidence of anxiety, alcohol and drug dependence, and cardiovascular disease is found in people with insomnia. Data indicate insomnia results from over-engaged arousal systems. Insomnia patients experience increased metabolic rate, body temperature, and heart rate, and elevated levels of norepinephrine and catecholamines. Pharmacologic options for the treatment of insomnia include benzodiazepine hypnotics, a selective melatonin receptor agonist, and sedating antidepressants. However, insomnia may be best treated with cognitive-behavioral therapy and instruction in good sleep hygiene, either alone or in concert with pharmacologic agents. Studies on the effects of insomnia treatment use variable methodologies or do not publish negative results, and there are currently no studies of treatment focusing on morbidity. Further research is necessary to better understand the effects of insomnia therapies on medical and psychiatric disorders.In this Clinical Information Supplement, Thomas Roth, PhD, describes the nature of insomnia and its pathophysiology. Next, Andrew D. Krystal, MD, MS, reviews morbidities associated with insomnia. Finally, Joseph A. Lieberman Ill, MD, MPH, provides an overview of therapeutics utilized in patients with insomnia, including behavioral therapies and pharmacologic options.
SN  - 1082-6319
AD  - Director, Sleep Disorders and Research Center, Henry Ford Health System, Detroit
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105933175&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104029958
T1  - Main challenges facing the pharmaceutical sector in Buchanan County, Virginia: a pilot study.
AU  - Gavaza, P.
AU  - Yan, W.
AU  - Campbell, J.
Y1  - 2012/10//Oct-Dec2012
N1  - Accession Number: 104029958. Language: English. Entry Date: 20140220. Revision Date: 20150710. Publication Type: Journal Article; research; tables/charts. Journal Subset: Australia & New Zealand; Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed. Special Interest: Consumer Health; Quality Assurance. NLM UID: 101174860. 
KW  - Pharmacy and Pharmacology -- Evaluation -- Virginia
KW  - Pharmacist Attitudes
KW  - Substance Abuse
KW  - Quality Improvement -- Methods
KW  - Human
KW  - Virginia
KW  - Pilot Studies
KW  - Cross Sectional Studies
KW  - Questionnaires
KW  - Delphi Technique
KW  - Convenience Sample
KW  - Self Report
KW  - Health Personnel
KW  - Descriptive Statistics
KW  - Patient Education
KW  - Quality Assessment
KW  - Data Analysis Software
KW  - Male
KW  - Female
SP  - 1
EP  - 6 6p
JO  - Rural & Remote Health
JF  - Rural & Remote Health
JA  - RURAL REMOTE HEALTH
VL  - 12
IS  - 4
PB  - James Cook University, Rural Health Research Unit
AB  - Introduction: Little is known about the challenges facing the pharmaceutical sector in rural counties in the USA. The aim of this pilot study is to determine the main challenges facing the pharmaceutical sector and suggestions for improving the sector in Buchanan County, a poor and marginalized county in Central Appalachia, Virginia. Methods: This cross-sectional study used the drop-by survey based on the first step of the modified Delphi Interview Technique. A convenience sample of healthcare professionals in Buchanan County were asked to complete a self-administered survey instrument between May and August 2011. Results: A total of 16 healthcare professionals including six pharmacists completed the survey. The respondents had worked for an average of 13.4 (SD=10.7) years in the County (range: 1-33 years). The main challenges facing the pharmaceutical sector were drug abuse (n=11), doctor shopping by patients (n=9), early refills (n=7) and drug shortage (n=6). Respondents suggested increased patient education by pharmacists (n=6) and better coordination and communication between pharmacy and doctor (n=6) to improve the pharmaceutical sector in the County. Conclusions: Drug abuse, doctor shopping, early refills and drug shortage are the main challenges facing the pharmaceutical sector in Buchanan County. Concerted efforts are required to solve these problems. More research is required to confirm these findings.
SN  - 1445-6354
AD  - Appalachian College of Pharmacy, Oakwood, Virginia, USA
U2  - PMID: 23140593.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106699618
T1  - Major risk factors for aneurysmal subarachnoid hemorrhage in the young are modifiable.
AU  - Broderick JP
AU  - Viscoli CM
AU  - Brott T
AU  - Kernan WN
AU  - Brass LM
AU  - Feldmann E
AU  - Morgenstern LB
AU  - Wilterdink JL
AU  - Horwitz RI
Y1  - 2003/06//2003 Jun
N1  - Accession Number: 106699618. Corporate Author: Hemorrhagic Stroke Project Investigators. Language: English. Entry Date: 20040206. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Allied Health; Biomedical; Peer Reviewed; USA. Grant Information: Supported by grants from Novartis Consumer Health, Inc (formerly Ciba Consumer Pharmaceuticals), Thompson Medical Company, Inc, and Chattem, Inc. NLM UID: 0235266. 
KW  - Subarachnoid Hemorrhage -- Epidemiology
KW  - Subarachnoid Hemorrhage -- Risk Factors
KW  - Smoking -- Epidemiology
KW  - Body Mass Index
KW  - Matched Case Control
KW  - Structured Questionnaires
KW  - Data Analysis Software
KW  - Odds Ratio
KW  - Confidence Intervals
KW  - Adult
KW  - Middle Age
KW  - Female
KW  - Male
KW  - Funding Source
KW  - Human
SP  - 1375
EP  - 1381 7p
JO  - Stroke (00392499)
JF  - Stroke (00392499)
JA  - STROKE
VL  - 34
IS  - 6
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - BACKGROUND AND PURPOSE: To identify risk factors for subarachnoid hemorrhage (SAH) and intracerebral hemorrhage, we designed a case-control study of men and women 18 to 49 years of age (the Hemorrhagic Stroke Project [HSP]). This report focuses on SAH. METHODS: Patients were recruited from 44 hospitals in the United States. Cases with SAH must have had a ruptured aneurysm documented by angiography or surgery. Two controls, identified by random digit dialing and matched to each patient for age, sex, race, and telephone exchange, were sought for each case subject. RESULTS: Between 1994 and 1999, 425 patients with SAH were enrolled in HSP, and 312 cases met the criteria for aneurysmal SAH. The present analyses also included 618 matched controls. Of the 312 cases, 66% were current cigarette smokers compared with 30% of controls (adjusted odds ratio [OR], 3.73; 95% CI, 2.67 to 5.21). Cocaine use within the previous 3-day period was reported by 3% of cases and no controls (bivariate exact OR, 24.97; 95% exact CI, 3.95 to infinity; adjusted estimate not calculable). Other independent risk factors in the multivariable model included hypertension (adjusted OR, 2.21; 95% CI, 1.48 to 3.29), low body mass index (OR, 1.59; 95% CI, 1.08 to 2.35), primary family history of hemorrhagic stroke (OR, 3.83; 95% CI, 1.73 to 8.46), caffeine in pharmaceutical products (OR, 2.48; 95% CI, 1.19 to 5.20), lower educational achievement (OR, 2.36; 95% CI, 1.44 to 3.87), and nicotine in pharmaceutical products (adjusted estimate not calculable). CONCLUSIONS: Aneurysmal SAH may be largely a preventable disease among the young and middle-aged because several prevalent risk factors can be modified by medication (eg, hypertension) or behavioral change (eg, cigarette smoking, cocaine use). The association of caffeine and nicotine in pharmaceutical products and aneurysmal SAH warrants further study.
SN  - 0039-2499
AD  - Department of Neurology, University of Cincinnati, College of Medicine, 231 Bethesda Ave, Cincinnati, OH 45267; joseph.Broderick@uc.edu
U2  - PMID: 12764233.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106699618&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107192205
T1  - Medical student knowledge of morphine for the management of cancer pain.
AU  - Sloan PA
AU  - Montgomery C
AU  - Musick D
Y1  - 1998/06//1998 Jun
N1  - Accession Number: 107192205. Language: English. Entry Date: 19990601. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Core Nursing; Nursing; Peer Reviewed; USA. NLM UID: 8605836. 
KW  - Students, Medical -- Psychosocial Factors
KW  - Cancer Pain -- Psychosocial Factors
KW  - Morphine -- Therapeutic Use
KW  - Cancer Pain -- Drug Therapy
KW  - Health Knowledge
KW  - Education, Medical -- Trends
KW  - Cancer Pain -- Education
KW  - Pretest-Posttest Design
KW  - Descriptive Statistics
KW  - Morphine -- Adverse Effects
KW  - Human
SP  - 359
EP  - 364 6p
JO  - Journal of Pain & Symptom Management
JF  - Journal of Pain & Symptom Management
JA  - J PAIN SYMPTOM MANAGE
VL  - 15
IS  - 6
CY  - New York, New York
PB  - Elsevier Science
AB  - Inadequate training of physicians contributes to the undertreatment of cancer pain. To address these concerns, the University of Kentucky has introduced a 4-week course for final-year medical students that teaches the principles of clinical pharmacology and pain management. The purposes of this study are to assess the knowledge deficits of final-year medical students about the use of morphine for cancer pain and to assess the efficacy of a short course on cancer pain management. Eighty-six final-year medical students completed a 22-item questionnaire assessing their knowledge and attitudes toward the use of morphine for cancer pain. Students indicated their agreement with each statement on a four-point scale (one, strongly disagree; four, strongly agree). All students then completed a compulsory short course on pain management. The course content included a 1-hr lecture on chronic nonmalignant pain, a 1-hr lecture on acute pain management, and a 1-hr lecture on cancer pain management. In addition, students completed small-group, problem-based learning modules on several aspects of pain management. After the course, all students completed the same 22-item survey. The alpha reliability score of the pretest instrument was 0.55, and the posttest reliability was 0.86. Upon course completion, students agreed most strongly (mean +/- SEM) that morphine should be given on a regular schedule for cancer pain (3.41 +/- 0.08), that cancer pain management frequently requires co-analgesics (3.36 +/- 0.06), and that patients with good pain relief function better than those with continuing pain (3.39 +/- 0.08). A comparison of pretest and posttest means on specific items suggested that the greatest amount of learning took place in the following content areas: morphine is a good oral analgesic; increases in cancer pain should be treated by increasing the morphine dose; respiratory depression is not a concern for cancer pain patients; and morphine can be used over a wide range of doses. The regular use of morphine was recognized as the treatment drug of choice for cancer pain. The students showed improved knowledge scores on ten of the 22 items on the posttest survey. A significant increase in learning occurred on six knowledge and attitude items. On only one item (nausea as a side effect of morphine) did the knowledge scores decrease on the posttest. A significant minority (40%) of senior medical students had deficits in knowledge about the use of morphine for cancer pain. The risk of addiction, respiratory depression, and tolerance were misunderstood by a significant minority (25%) of students. (c) U.S. Cancer Pain Relief Committee, 1999 Published by Elsevier, New York, New York
SN  - 0885-3924
AD  - Department of Anesthesiology, University of Kentucky Hospital, 800 Rose St., Lexington, KY 40536
U2  - PMID: 9670636.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107192205&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104627258
T1  - Medication Therapy and Patient Care.
Y1  - 2011/01//2011/2012
N1  - Accession Number: 104627258. Language: English. Entry Date: 20120201. Revision Date: 20150711. Publication Type: Journal Article; practice guidelines. Journal Subset: Biomedical; USA. NLM UID: 101244593. 
KW  - Health Care Delivery
KW  - Organizational Policies
KW  - Pharmacy Service -- Administration
KW  - Collaboration
KW  - Critical Path -- Methods
KW  - Cultural Competence
KW  - Dietary Supplements
KW  - Disaster Planning
KW  - Documentation
KW  - Drug Monitoring
KW  - Emergency Service
KW  - Health Services Accessibility
KW  - HIV Infections
KW  - Immunization
KW  - Infection Control
KW  - Interprofessional Relations
KW  - Patient Education
KW  - Pediatric Care
KW  - Pharmacists -- Organizations -- United States
KW  - United States
KW  - Primary Health Care
KW  - Privacy and Confidentiality
KW  - Professional Role
KW  - Professional Practice -- Standards
KW  - Pharmacists
KW  - Public Health
KW  - Scope of Practice
KW  - Substance Abuse -- Prevention and Control
KW  - Palliative Care
KW  - Quality of Health Care
KW  - Hospitalists
KW  - Patient Care
KW  - Counseling
KW  - Hospice Care
KW  - Anesthesiology
KW  - Surgery, Elective
KW  - Pharmacy Technicians
KW  - Education, Pharmacy
KW  - Medical Records
KW  - Drug Therapy
KW  - Pain -- Therapy
KW  - Doping in Sports
KW  - Healthcare Disparities
KW  - Institute of Medicine (U.S.)
KW  - Patient Rounds
KW  - Medication Systems
KW  - Administrative Personnel
KW  - Drug Information Services
KW  - Drug and Narcotic Control
SP  - 231
EP  - 334 104p
JO  - Best Practices for Hospital & Health-System Pharmacy
JF  - Best Practices for Hospital & Health-System Pharmacy
JA  - BEST PRACT HOSP HEALTH SYST PHARM
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
SN  - 1555-8975
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104627258&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106188077
T1  - Mental health nursing students' relationships with the pharmaceutical industry.
AU  - Ashmore R
AU  - Carver N
AU  - Banks D
Y1  - 2007/08//
N1  - Accession Number: 106188077. Language: English. Entry Date: 20071109. Revision Date: 20150819. Publication Type: Journal Article; research; tables/charts. Journal Subset: Core Nursing; Europe; Nursing; Peer Reviewed; UK & Ireland. Special Interest: Nursing Education. NLM UID: 8511379. 
KW  - Community Mental Health Nursing -- Education -- United Kingdom
KW  - Interprofessional Relations -- Ethical Issues
KW  - Marketing -- Ethical Issues
KW  - Pharmaceutical Companies -- United Kingdom
KW  - Student Attitudes -- Evaluation -- United Kingdom
KW  - Students, Nursing
KW  - Advertising
KW  - Content Analysis
KW  - Convenience Sample
KW  - Descriptive Research
KW  - Descriptive Statistics
KW  - Questionnaires
KW  - Survey Research
KW  - United Kingdom
KW  - Human
SP  - 551
EP  - 560 10p
JO  - Nurse Education Today
JF  - Nurse Education Today
JA  - NURSE EDUC TODAY
VL  - 27
IS  - 6
CY  - New York, New York
PB  - Elsevier Science
AB  - INTRODUCTION: The medical profession's relationship with the pharmaceutical industry (PI) has come under increased scrutiny in recent years, however little is known on the subject in mental health nursing. AIMS: The study sought to investigate: (1) the frequency of contact between mental health nursing students and PI employees; (2) students' attitudes and beliefs about their relationship with the PI; (3) the range of 'gifts', promotional items and hospitality accepted or seen in clinical environments by students in a one year period; and (4) students' attitudes to 'gifts', promotional items and hospitality offered by the industry. METHOD: Employing a survey design, a 35-item questionnaire was distributed to 472 students at two universities in the UK. Data were analysed from 347 respondents by means of descriptive statistics and simple content analysis. RESULTS: The findings suggest that students have significant contact with the industry through one-to-one meetings with pharmaceutical representatives (PRs) and by attending events giving information on specific drugs or general mental health issues. Students also identified a number of benefits (e.g. receiving 'up-to-date' information on new drugs) and problems (e.g. the potential influence exerted on practitioners to use their drugs) arising out of this contact. Most students (79.8%) had accepted some form of 'gift' from the industry but few (11.5%) believed it was unacceptable to do so. The presence of promotional items in the clinical environment was seen as advertising (84.4%) but few students (19.3%) believed clinical environment should be free of these items. Over half (57.1%) of the students believed that PRs did not always give unbiased information but thought that they and mental health nurses in general would be able to detect any bias. CONCLUSIONS: In parallel with medicine, the study has shown that the pharmaceutical industry has at least the potential to influence mental health nursing students. Within medicine this realisation has triggered a vigorous debate on how medical schools should respond to the promotional activities of the PI. We suggest this study goes some way to demonstrating there is a need for these issues to be debated in the education of mental health nurses.
SN  - 0260-6917
AD  - Sheffield Hallam University, Faculty of Health and Wellbeing, Mundella House, Collegiate Crescent, S1 1WB, United Kingdom
U2  - PMID: 17113686.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106188077&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106355228
T1  - Methamphetamine: putting the brakes on speed.
AU  - Gettig JP
AU  - Grady SE
AU  - Nowosadzka I
Y1  - 2006/04//
N1  - Accession Number: 106355228. Language: English. Entry Date: 20061103. Revision Date: 20150820. Publication Type: Journal Article; pictorial; review; tables/charts. Journal Subset: Nursing; Peer Reviewed; USA. NLM UID: 9206498. 
KW  - Methamphetamine -- Adverse Effects
KW  - Substance Abuse
KW  - Adolescence
KW  - Child
KW  - Child Welfare
KW  - Clinical Assessment Tools
KW  - Drug and Narcotic Control -- Legislation and Jurisprudence -- United States
KW  - Drug Rehabilitation Programs
KW  - Information Resources
KW  - Methamphetamine -- History
KW  - Methamphetamine -- Legislation and Jurisprudence -- United States
KW  - Methamphetamine -- Pharmacodynamics
KW  - Methamphetamine -- Pharmacokinetics
KW  - School Health Nursing
KW  - Street Drugs
KW  - Substance Abuse -- Diagnosis
KW  - Substance Abuse -- Epidemiology
KW  - Substance Abuse -- Risk Factors
KW  - Substance Abuse -- Symptoms
KW  - Substance Abuse -- Therapy
KW  - United States
KW  - World Wide Web
SP  - 66
EP  - 73 8p
JO  - Journal of School Nursing (Allen Press Publishing Services Inc.)
JF  - Journal of School Nursing (Allen Press Publishing Services Inc.)
JA  - J SCH NURS (ALLEN PRESS)
VL  - 22
IS  - 2
CY  - Lawrence, Kansas
PB  - Allen Press Publishing Services Inc.
AB  - In only recent history, illicit use of methamphetamine, once isolated to urban areas on the West Coast, has spread into rural areas of the Midwest and southern United States. Although past and current methamphetamine legislation has increased penalties for methamphetamine manufacturers and tightened restrictions on sales of known precursors, the problem still persists. In fact, a 2004 survey indicates that an alarming 6.2% of high school seniors have tried methamphetamine. A number of biological, genetic, and environmental factors influence children's and adolescents' paths to substance abuse. Nurses should recognize the symptoms of methamphetamine abuse, which include agitation; aggressive behavior; rapid mood swings; hypertension; tachycardia; and eventually lesion-marked skin, clinical depression, and paranoid psychosis. Treatment for methamphetamine addiction includes behavioral therapy. Research on pharmacologic therapy is lacking. Educating youth on methamphetamine prevention appears to be the best approach to curb the spreading use of this addictive and deadly drug.
SN  - 1059-8405
AD  - Assistant Professor, Pharmacy Practice, Midwestern University Chicago College of Pharmacy in Downers Grove, IL
U2  - PMID: 16563028.
DO  - 10.1177/105984050602200202
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106355228&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105663833
T1  - Methodology of an ongoing, randomized controlled trial to prevent falls through enhanced pharmaceutical care.
AU  - Ferreri S
AU  - Roth MT
AU  - Casteel C
AU  - Demby KB
AU  - Blalock SJ
Y1  - 2008/06//
N1  - Accession Number: 105663833. Language: English. Entry Date: 20081010. Revision Date: 20150711. Publication Type: Journal Article; research; randomized controlled trial. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Gerontologic Care. NLM UID: 101190325. 
KW  - Accidental Falls -- Prevention and Control
KW  - Clinical Trials -- Methods
KW  - Pharmacy, Retail
KW  - Aged
KW  - Aged, 80 and Over
KW  - Algorithms
KW  - Female
KW  - Human
KW  - Male
KW  - Multicenter Studies
KW  - Prospective Studies
KW  - Randomized Controlled Trials
KW  - Study Design
SP  - 61
EP  - 81 21p
JO  - American Journal of Geriatric Pharmacotherapy
JF  - American Journal of Geriatric Pharmacotherapy
JA  - AM J GERIATR PHARMACOTHER
VL  - 6
IS  - 2
CY  - New York, New York
PB  - Elsevier Science
AB  - Background: Falls are the leading cause of both fatal and nonfatal injuries among adults aged >/=65 years in the United States. Past research suggests that individuals taking multiple medications are at increased risk of falls. Central nervous system-active drugs in particular have been associated with increased risk. Objective: The goal of this research was to describe the design of a study evaluating the effectiveness of a community pharmacy-based falls prevention program. Also presented are the algorithms used to identify high-risk patients based on their prescription profile records and to deliver the experimental intervention. Methods: The study is a randomized controlled trial. The target population was community-dwelling older adults (aged >/=65 years) at high risk for future falls because: (1) they had experienced >/=1 fall within the 12-month period preceding study enrollment; (2) they were currently using >/=4 chronic prescription medications; and (3) they were taking >/=1 of the high-risk medications targeted by the intervention. Participants were recruited using pharmacy prescription profile records. Individuals in the intervention group received a face-to-face medication consultation provided by a community pharmacy resident. Identification of drug therapy problems and therapeutic recommendations was guided by a series of algorithms developed for this study. All participants were followed up for 24 months. The primary study end points were: (1) time to first fall; and (2) proportion of participants who experienced >/=1 fall during the first year of follow-up. Results: Participant enrollment began in September 2005 and was completed in August 2007. A total of 186 individuals were enrolled in the study (mean [SD] age, 74.8 [6.9] years; 132 women, 54 men), and 67 have completed the first year of follow-up. Conclusions: The study is using a rigorous randomized controlled research design, which will enhance the internal validity of its findings. Results of the study, which will be reported after the completion of follow-up data collection activities, will enable us to assess the effects of the intervention on both medication use and the incidence of falls. If the intervention is found to be effective, it will provide a resource for community pharmacists working with older adults at high risk of medication-related falls.
SN  - 1543-5946
AD  - Division of Pharmacy Practice and Experiential Education, School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
U2  - PMID: 18675765.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105663833&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105741692
T1  - Model for medication therapy management in a university clinic.
AU  - Kliethermes MA
AU  - Schullo-Feulner AM
AU  - Tilton J
AU  - Kim S
AU  - Pellegrino AN
Y1  - 2008/05//5/1/2008
N1  - Accession Number: 105741692. Language: English. Entry Date: 20080613. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Drug Therapy
KW  - Management
KW  - Nursing Care Plans
KW  - Academic Medical Centers
KW  - Continuity of Patient Care -- Trends
KW  - Outpatients
KW  - Pharmacists
KW  - Pharmacy Service
KW  - Referral and Consultation
SP  - 844
EP  - 856 13p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 65
IS  - 9
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
AB  - PURPOSE: Experience with a referral-based medication therapy management (MTM) clinic in a university medical center is described. SUMMARY: The MTM clinic's mission is to assist patients who take multiple medications due to multiple chronic conditions with the management of their drug therapy to improve or maintain their health and prevent or minimize drug-related problems. The clinical services provided at the clinic have evolved into a comprehensive program providing five distinct service areas: access, adherence, coordination of care, medication therapy review, and education. During initial visits, patient information is collected, patients are interviewed, medications are reconciled, and the pharmacist identifies and attempts to solve any immediate drug-related problems and concerns. Routine visits are scheduled monthly to coincide with a patient's medication refills. On a typical day, a minimum of two MTM pharmacists and one pharmacy technician staff the clinic. On two days of the week, three MTM pharmacists are available in the clinic. The clinic averages 9-13 scheduled patient visits per day. The MTM clinic functions as a subset of the outpatient pharmacy and is merged financially in the general operational budget of the ambulatory care pharmacy. This model of MTM patient care is intensive and comprehensive and is significantly different from the majority of MTM models currently provided by Medicare Part D plans. CONCLUSION: A referral-based MTM clinic managed by pharmacists at a university medical center outpatient pharmacy provides care to patients with the goal of improving medication access, medication adherence, continuity of care, medication therapy management, and patient education.
SN  - 1079-2082
AD  - Department of Pharmacy Practice, Chicago College of Pharmacy, Midwestern University, Downers Grove, IL 60515, USA. mkliet@midwestern.edu
U2  - PMID: 18436731.
DO  - 10.2146/ajhp070338
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104125995
T1  - Modeling the Impact of Simulated Educational Interventions on the Use and Abuse of Pharmaceutical Opioids in the United States: A Report on Initial Efforts.
AU  - Wakeland, Wayne
AU  - Nielsen, Alexandra
AU  - Schmidt, Teresa D.
AU  - McCarty, Dennis
AU  - Webster, Lynn R.
AU  - Fitzgerald, John
AU  - Haddox, J. David
Y1  - 2013/10/02/Oct2013 Supplement
N1  - Accession Number: 104125995. Language: English. Entry Date: 20131230. Revision Date: 20150710. Publication Type: Journal Article; research; tables/charts. Supplement Title: Oct2013 Supplement. Journal Subset: Health Promotion/Education; Peer Reviewed; USA. Special Interest: Psychiatry/Psychology. Grant Information: Wayne Wakeland, Teresa D. Schmidt, Dennis McCarty, Alexandra Nielsen, and Lynn R. Webster were compensated through a research grant to Portland State University funded by Purdue Pharma, L.P.. NLM UID: 9704962. 
KW  - Substance Abuse -- Education -- United States
KW  - Narcotics
KW  - Health Education -- United States
KW  - Simulations
KW  - Substance Dependence -- Education -- United States
KW  - Human
KW  - United States
KW  - Secondary Analysis
KW  - Prospective Studies
KW  - Overdose -- Mortality
KW  - Substance Abuse -- Complications
KW  - Overdose -- Prevention and Control
KW  - Narcotics -- Adverse Effects
KW  - Models, Statistical
KW  - Drug Utilization
KW  - Drugs, Prescription
KW  - Street Drugs
KW  - Prescribing Patterns
KW  - Funding Source
SP  - 74S
EP  - 86S 1p
JO  - Health Education & Behavior
JF  - Health Education & Behavior
JA  - HEALTH EDUC BEHAV
VL  - 40
IS  - 1
CY  - Thousand Oaks, California
PB  - Sage Publications Inc.
SN  - 1090-1981
AD  - Portland State University, Portland, OR, USA
AD  - Oregon Health and Science University, Portland, OR, USA
AD  - CRI Lifetree Clinical Research, Salt Lake City, UT, USA
AD  - Purdue Pharma LP, Stamford, CT, USA
AD  - Purdue Pharma LP, Stamford, CT, USA, Tufts University, Boston, MA, USA
U2  - PMID: 24084403.
DO  - 10.1177/1090198113492767
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104125995&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106689830
T1  - Multidisciplinary medication review in nursing home residents: what are the most significant drug-related problems? The Bergen District Nursing Home (BEDNURS) study.
AU  - Ruths S
AU  - Straand J
AU  - Nygaard HA
Y1  - 2003/06//
N1  - Accession Number: 106689830. Language: English. Entry Date: 20040109. Revision Date: 20150711. Publication Type: Journal Article; pictorial; research; tables/charts. Journal Subset: Blind Peer Reviewed; Europe; Expert Peer Reviewed; Health Services Administration; Peer Reviewed; UK & Ireland. NLM UID: 101136980. 
KW  - Drug Therapy -- Adverse Effects
KW  - Drug Utilization
KW  - Nursing Homes -- Administration -- Norway
KW  - Utilization Review
KW  - Aged
KW  - Aged, 80 and Over
KW  - Chi Square Test
KW  - Cross Sectional Studies
KW  - Descriptive Statistics
KW  - Female
KW  - Health Services Misuse
KW  - Male
KW  - Medication Errors
KW  - Multidisciplinary Care Team
KW  - Norway
KW  - Psychotropic Drugs -- Therapeutic Use
KW  - Record Review
KW  - Spearman's Rank Correlation Coefficient
KW  - Statistical Significance
KW  - T-Tests
KW  - Human
SP  - 176
EP  - 180 5p
JO  - Quality & Safety in Health Care
JF  - Quality & Safety in Health Care
JA  - QUAL SAF HEALTH CARE
VL  - 12
IS  - 3
PB  - BMJ Publishing Group
AB  - AIM: Based on a multidisciplinary review of drug use in nursing home residents, this study aimed to identify the most frequent clinically relevant medication problems and to analyse them according to the drugs involved and types of problems. METHODS: Cross sectional study auditing drug use by 1354 residents in 23 nursing homes in Bergen, Norway. Data were collected in 1997. A physician/pharmacist panel performed a comprehensive medication review with regard to indications for drug use and active medical conditions. The drug related problems were subsequently classified according to the drugs involved and types of problems (indication, effectiveness, and safety issues). RESULTS: 2445 potential medication problems were identified in 1036 (76%) residents. Psychoactive drugs accounted for 38% of all problems; antipsychotics were the class most often involved. Multiple psychoactive drug use was considered particularly problematic. Potential medication problems were most frequently classified as risk of adverse drug reactions (26%), inappropriate drug choice for indication (20%), and underuse of beneficial treatment (13%). CONCLUSIONS: Three of four nursing home residents had clinically relevant medication problems, most of which were accounted for by psychoactive drugs. The most frequent concerns were related to adverse drug reactions, drug choice, and probable undertreatment.
SN  - 1475-3898
AD  - Section for Geriatric Medicine, Department of Public health and Primary Health Care, University of Bergen, Ulriksdal 8c, N-5009, Bergen, Norway; sabine.ruths@isf.uib.no
U2  - PMID: 12792006.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105329683
T1  - New constructs and assessments for relapse and continued use potential in the ASAM Patient Placement Criteria.
AU  - Gastfriend DR
AU  - Rubin A
AU  - Sharon E
AU  - Turner WM
AU  - Anton RF
AU  - Donovan DM
AU  - Gorski T
AU  - Marlatt GA
AU  - Maisto S
AU  - Schultz TK
AU  - Shulman GD
Y1  - 2003/03/02/2003 Supplement 1
N1  - Accession Number: 105329683. Language: English. Entry Date: 20091113. Revision Date: 20150711. Publication Type: Journal Article; review. Supplement Title: 2003 Supplement 1. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9107051. 
KW  - Patient Selection
KW  - Substance Use Disorders -- Diagnosis
KW  - Substance Use Disorders -- Rehabilitation
KW  - Substance Use Rehabilitation Programs -- Utilization
KW  - Adaptation, Psychological
KW  - Aggression
KW  - DSM
KW  - Questionnaires
KW  - Recurrence
KW  - Reinforcement (Psychology)
SP  - 95
EP  - 111 17p
JO  - Journal of Addictive Diseases
JF  - Journal of Addictive Diseases
JA  - J ADDICT DIS
VL  - 22
PB  - Taylor & Francis Ltd
AB  - One area of intensive study in recent years in addiction research is the characterization and prediction of relapse risk. Given the growing list of findings and assessment tools in this area, in preparation for the second edition, revised volume of the Patient Placement Criteria (PPC) of the American Society of Addiction Medicine (ASAM), a workgroup of the Coalition for National Criteria was assigned the task of creating a revised conceptual organization for Dimension 5: Relapse/ Continued Use Potential. The workgroup conducted a review of the previous Dimension 5 constructs and criteria, including a decision analysis of the previous Dimension 5 decision rules. Following that analysis, field data from the ASAM Criteria Validity Study at Massachusetts General Hospital and Harvard Medical School were analyzed from a large cohort of public and indigent patients in eastern Massachusetts. After determining the concurrent validity of the Dimension 5 decision rules and their limitations, the decision rules were rewritten to gain improved validity. This exercise revealed techniques that can and should be used to improve the discrimination of levels of care among all Dimensions. Finally, the workgroup expanded and refined the constructs that should comprise a revised Dimension 5. This revised list of constructs is sequential and hierarchical. It offers face validity on several levels of current basic and clinical research knowledge: behavioral pharmacology, behavioral psychology, learning theory and psychopathology. While the Second Edition-Revised volume of the ASAM PPC (PPC-2R) does not go so far as to propose final decision rules for Dimension 5 based on these new constructs, it does recommend pilot adoption of several new assessment tools for this dimension and provides the framework incorporating those constructs and assessments in the next complete PPC edition.
SN  - 1055-0887
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105329683&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104105315
T1  - New technologies for examining the role of neuronal ensembles in drug addiction and fear.
AU  - Cruz, Fabio C
AU  - Koya, Eisuke
AU  - Guez-Barber, Danielle H
AU  - Bossert, Jennifer M
AU  - Lupica, Carl R
AU  - Shaham, Yavin
AU  - Hope, Bruce T
Y1  - 2013/11//
N1  - Accession Number: 104105315. Language: English. Entry Date: 20150522. Revision Date: 20160302. Publication Type: journal article; review. Journal Subset: Biomedical; Europe; UK & Ireland. Grant Information: ZIA DA000467-06//Intramural NIH HHS/United States. NLM UID: 100962781. 
KW  - Fear
KW  - Neurons -- Pathology
KW  - Substance Use Disorders
KW  - Animals
KW  - Brain
KW  - Brain -- Physiology
KW  - Conditioning (Psychology)
KW  - Dopamine -- Physiology
KW  - Genes
KW  - Limbic System -- Physiology
KW  - Mice
KW  - Rats
KW  - Reward
SP  - 743
EP  - 754 12p
JO  - Nature Reviews Neuroscience
JF  - Nature Reviews Neuroscience
JA  - NATURE REV NEUROSCI
VL  - 14
IS  - 11
CY  - London, <Blank>
PB  - Nature Publishing Group
AB  - Correlational data suggest that learned associations are encoded within neuronal ensembles. However, it has been difficult to prove that neuronal ensembles mediate learned behaviours because traditional pharmacological and lesion methods, and even newer cell type-specific methods, affect both activated and non-activated neurons. In addition, previous studies on synaptic and molecular alterations induced by learning did not distinguish between behaviourally activated and non-activated neurons. Here, we describe three new approaches--Daun02 inactivation, FACS sorting of activated neurons and Fos-GFP transgenic rats--that have been used to selectively target and study activated neuronal ensembles in models of conditioned drug effects and relapse. We also describe two new tools--Fos-tTA transgenic mice and inactivation of CREB-overexpressing neurons--that have been used to study the role of neuronal ensembles in conditioned fear.
SN  - 1471-003X
AD  - Intramural Research Program, National Institute on Drug Abuse-National Institutes of Health, 251 Bayview Boulevard, Baltimore, Maryland 21224, USA.
U2  - PMID: 24088811.
DO  - 10.1038/nrn3597
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104105315&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104468462
T1  - New Zealand pharmacists' experiences, practices and views regarding antibiotic use without prescription.
AU  - Dameh, Majd
AU  - Norris, Pauline
AU  - Green, James
Y1  - 2012/06//
N1  - Accession Number: 104468462. Language: English. Entry Date: 20120817. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Australia & New Zealand; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; Public Health. Special Interest: Public Health. Grant Information: The authors wish to thank NZ's National School of Pharmacy, University of Otago for their funding of this research.. NLM UID: 101524060. 
KW  - Antibiotics -- Administration and Dosage
KW  - Drug Administration -- Psychosocial Factors
KW  - Pharmacists -- Psychosocial Factors
KW  - Substance Abuse -- Psychosocial Factors
KW  - Adult
KW  - Aged
KW  - Audiorecording
KW  - Descriptive Statistics
KW  - Drug Administration -- Ethical Issues
KW  - Employer-Employee Relations
KW  - Female
KW  - Field Notes
KW  - Funding Source
KW  - Human
KW  - Male
KW  - Middle Age
KW  - New Zealand
KW  - Purposive Sample
KW  - Qualitative Studies
KW  - Self Report
KW  - Semi-Structured Interview
SP  - 131
EP  - 140 10p
JO  - Journal of Primary Health Care
JF  - Journal of Primary Health Care
JA  - J PRIM HEALTH CARE
VL  - 4
IS  - 2
CY  - Clayton, VIC, <Blank>
PB  - CSIRO Publishing
AB  - INTRODUCTION: Very few studies have investigated pharmacists' views, experiences and practices regarding the use of antibiotics without prescription. This study aimed to explore through self-report and hypothetical scenarios what factors determine New Zealand pharmacists' behaviour and attitudes towards non-prescription use of antibiotics. METHODS: A purposeful sample of 35 registered community pharmacists of differing ethnic backgrounds was selected from a mixture of pharmacies that predominantly either serve New Zealand European customers or customers of other ethnicities. Semi-structured interviews including general background questions and six hypothetical scenarios were used for the investigation. Pharmacists' ethnicity, education, years of experience, and customers' ethnicity may influence their views, experiences and practices regarding the use of antibiotics without prescription. Customer demand or expectation, business orientation and competitiveness within community pharmacies, standards and practice of fellow pharmacists, ethics and professionalism, legislation, enforcement of the legislation, and apprehension of the consequences of such practice were hypothesised to have an effect on antibiotic use or supply without prescription by pharmacists. FINDINGS : The supply of antibiotics without prescription is not common practice in New Zealand. However, personal use of antibiotics without prescription by pharmacists may have been underestimated. Pharmacists were aware of legalities surrounding selling and using antibiotics and practised accordingly, yet many used antibiotics without prescription to treat themselves and/or spouses or partners. Many pharmacists also reported that under certain legislative, and regulatory and situational conditions they would sell antibiotics without a prescription. CONCLUSION: Views and practices regarding antibiotic use without prescription by community pharmacists require further exploration.
SN  - 1172-6164
AD  - School of Pharmacy, University of Otago, PO Box 56, Dunedin, New Zealand. drmajddameh@gmail.com.
U2  - PMID: 22675697.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104468462&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109771116
T1  - Nod and wave: An Internet study of the codeine intoxication phenomenon.
AU  - Van Hout, Marie Claire
Y1  - 2015/01//
N1  - Accession Number: 109771116. Language: English. Entry Date: 20150918. Revision Date: 20150923. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9014759. 
KW  - Codeine -- Administration and Dosage
KW  - Internet
KW  - Substance Use Disorders -- Epidemiology
KW  - Substance Withdrawal Syndrome -- Epidemiology
KW  - Codeine -- Adverse Effects
KW  - Overdose -- Epidemiology
KW  - Harm Reduction
KW  - Human
KW  - Pain -- Drug Therapy
KW  - Public Health
KW  - Risk Management -- Methods
SP  - 67
EP  - 77 11p
JO  - International Journal of Drug Policy
JF  - International Journal of Drug Policy
JA  - INT J DRUG POLICY
VL  - 26
IS  - 1
CY  - New York, New York
PB  - Elsevier Science
AB  - BACKGROUND: The non-medical use of pharmaceutical opioids such as codeine is of increasing public health concern. The aim of the study was to describe codeine intoxication experiences amongst recreational drug users, as posted on public Internet forums. METHODS: Internet searches were carried out by using the specific key word 'codeine' and in combination with 'experience', 'report', 'trip' and 'forum'. 96 Trip reports and 156 thread discussions relating to the sole use of codeine were analysed using the empirical phenomenological psychological (EPP) method. Nine themes and 72 categories emerged. RESULTS: Narratives illustrated transitions between medical and non-medical use of codeine for dulling of emotional and/or physical pain, opiate withdrawal management and for intoxication. Codeine's appeal centred on access via family medicine cabinets, prescribers and pharmacies. Discussion and dissemination of indigenous harm reduction tactics included the learning to appreciate codeine's effect via moderated use in optimal settings, avoidance of tolerance by use of informed dosing schedules, cold water extraction of codeine, and using codeine as an alternative to stronger opioids. Oral and rectal routes were favoured, with awareness on forums of the harms of intravenous and subcutaneous injection. 250mg was recommended to optimise recreational outcomes. Forum users describe potentiating practices and using over-the-counter medications to improve intoxication experiences and reduce unpleasant side effects. Dissociative effects, ability to ignore physical and emotional pain, codeine induced synaesthesia and altered states of consciousness were described. Overdose was characterised by anaesthesia, severe chest and stomach pain, respiratory depression, panic and fear of death. CONCLUSION: Efforts to ensure legitimate codeine use for pain and reduction of aberrant behaviours centre on evidence based screening, risk minimisation, prescription monitoring and specific treatment protocols. This study shows that internet drug forums drive communal knowhow and indigenous harm reduction strategies, and warrant consideration as viable public health mechanisms for informing users.
SN  - 0955-3959
U2  - PMID: 25052240.
DO  - 10.1016/j.drugpo.2014.06.016
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109771116&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103980218
T1  - Nondiscriminatory, Multidisciplinary Care for Neonatal Abstinence Syndrome.
AU  - Asher, Sheila
AU  - Williams, Kecia
AU  - Richardson, Rela
Y1  - 2014/06/02/
N1  - Accession Number: 103980218. Language: English. Entry Date: 20140917. Revision Date: 20150710. Publication Type: Journal Article; abstract. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Special Interest: Obstetric Care; Pediatric Care; Women's Health. NLM UID: 8503123. 
KW  - Neonatal Abstinence Syndrome
KW  - Substance Abuse, Perinatal
KW  - Ohio
KW  - Needs Assessment
KW  - Family Centered Care
SP  - S35
EP  - S35 1p
JO  - JOGNN: Journal of Obstetric, Gynecologic & Neonatal Nursing
JF  - JOGNN: Journal of Obstetric, Gynecologic & Neonatal Nursing
JA  - JOGNN
VL  - 43
IS  - Supp 1
CY  - Philadelphia, Pennsylvania
PB  - Elsevier Inc.
AB  - Purpose for the Program The State of Ohio has recommended that all labor and delivery hospitals drug test women in labor to better detect infants with neonatal abstinence syndrome (NAS). A multidisciplinary approach to caring for infants diagnosed with NAS is essential to optimizing outcomes. An innovative education session was developed for all disciplines to promote nondiscriminatory evidence-based care. Proposed Change Based upon the recommendations from the State of Ohio, needs assessment of the perinatal staff, and an increase in maternal drug and substance abuse in the Greater Cincinnati Area, a community-based Level II Family Birth Center examined and developed an innovative multidisciplinary education program about the plan of care for infants diagnosed with NAS that provided nondiscriminatory family-centered care and improved inter-rater reliability with the Finnegan Scoring Tool. Implementation, Outcomes, and Evaluation In response to the increase in maternal drug abuse, the NAS education program was implemented in collaboration with nurses, physicians, social workers, pharmacists, and spiritual care. Together the team created a multidisciplinary education program that covered incidence and general discussion of NAS; identification of fetal, maternal, and neonatal effects of commonly abused perinatal drug exposure; the role of diversity and compassionate care in relation to perinatal drug exposure; social service involvement in relation to perinatal maternal drug abuse and NAS; types of drug-testing techniques, pharmacologic protocol, and treatment for NAS; nonpharmacologic treatment for newborns with NAS; and scoring the signs and symptoms of NAS using the Finnegan Scoring Tool. As a result, the NAS education program fostered interdisciplinary communication, identified standards of care, and promoted nondiscriminatory care. Implications for Nursing Practice With the application of the content covered in the NAS education program, nurses are able to facilitate nondiscriminatory family-centered care with an infant diagnosed with NAS. With the increase of NAS at the Level II facility, the education program improved delivery of care, enhanced multidisciplinary communication, and improved inter-rater reliability for the Finnegan Scoring Tool.
SN  - 0884-2175
AD  - Mercy Health-Fairfield Hospital, Cincinnati, OH
DO  - 10.1111/1552-6909.12413
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103980218&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104928463
T1  - Nonmedical Prescription Stimulant Use Among College Students: Why We Need to Do Something and What We Need to Do.
AU  - Arria AM
AU  - DuPont RL
Y1  - 2010/10//Oct-Dec2010
N1  - Accession Number: 104928463. Language: English. Entry Date: 20101229. Revision Date: 20150711. Publication Type: Journal Article; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Psychiatry/Psychology. NLM UID: 9107051. 
KW  - Central Nervous System Stimulants
KW  - Drugs, Prescription
KW  - Students, College
KW  - Physicians
KW  - Pharmaceutical Companies
KW  - Health Personnel
SP  - 417
EP  - 426 10p
JO  - Journal of Addictive Diseases
JF  - Journal of Addictive Diseases
JA  - J ADDICT DIS
VL  - 29
IS  - 4
PB  - Taylor & Francis Ltd
AB  - This article summarizes recent research findings on nonmedical use of prescription stimulants and outlines a multi-pronged strategic approach for responding to this unique problem among college students. Students, health professionals, parents, the pharmaceutical industry, and institutions of higher education all play roles in this response. Moreover, the academic community should view the translation of research findings as an important responsibility that can help dispel the myths often perpetuated in the media. The nonmedical use of prescription stimulants is a complex behavior and should be viewed in the larger context of alcohol and drug involvement among young adults. Strategies to reduce nonmedical use of prescription stimulants might have direct application to the abuse of other prescription drugs, including opiates.
SN  - 1055-0887
AD  - Department of Family Science, Center on Young Adult Health and Development, University of Maryland School of Public Health, College Park, MD
U2  - PMID: 20924877.
DO  - 10.1080/10550887.2010.509273
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104928463&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105376547
T1  - Nonmedical use of prescription opioids and stimulants among student pharmacists.
AU  - Lord S
AU  - Downs G
AU  - Furtaw P
AU  - Chaudhuri A
AU  - Silverstein A
AU  - Gammaitoni A
AU  - Budman S
Y1  - 2009/07//Jul/Aug2009
N1  - Accession Number: 105376547. Language: English. Entry Date: 20090807. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 101176252. 
KW  - Analgesics, Opioid
KW  - Central Nervous System Stimulants
KW  - Drugs, Prescription
KW  - Schools, Health Occupations -- Statistics and Numerical Data
KW  - Students, Pharmacy -- Statistics and Numerical Data
KW  - Substance Use Disorders -- Epidemiology
KW  - Adolescence
KW  - Adult
KW  - Alcohol Drinking -- Epidemiology
KW  - Attention -- Drug Effects
KW  - Cross Sectional Studies
KW  - Educational Status
KW  - Female
KW  - Male
KW  - Pain -- Drug Therapy
KW  - Peer Group
KW  - Prevalence
KW  - Questionnaires
KW  - Recreation
KW  - Risk Factors
KW  - Sex Factors
KW  - Smoking -- Epidemiology
KW  - Substance Use Disorders -- Ethnology
KW  - Surveys
KW  - United States
KW  - Whites -- Statistics and Numerical Data
KW  - Human
SP  - 519
EP  - 528 10p
JO  - Journal of the American Pharmacists Association: JAPhA
JF  - Journal of the American Pharmacists Association: JAPhA
JA  - J AM PHARM ASSOC
VL  - 49
IS  - 4
CY  - Washington, District of Columbia
PB  - American Pharmacists Association
SN  - 1544-3191
AD  - National Development and Research Institutes, Inc, New York, USA. lord@ndri.org
U2  - PMID: 19589764.
DO  - 10.1331/JAPhA.2009.08027
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105376547&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105007049
T1  - Nursing role in the pharmaceutical life cycle.
AU  - Becker J
AU  - Méndez-Quigley T
AU  - Phillips M
Y1  - 2010/10//2010 Oct-Dec
N1  - Accession Number: 105007049. Language: English. Entry Date: 20101203. Revision Date: 20150818. Publication Type: Journal Article. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Special Interest: Nursing Administration. NLM UID: 7703976. 
KW  - Drugs, Prescription
KW  - Environmental Pollution
KW  - Medical Waste Disposal
KW  - Nursing Role
KW  - Drug Approval
KW  - Drug Design
KW  - United States Food and Drug Administration
KW  - Water Supply
SP  - 297
EP  - 305 9p
JO  - Nursing Administration Quarterly
JF  - Nursing Administration Quarterly
JA  - NURS ADM Q
VL  - 34
IS  - 4
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - Biologically active, nontherapeutic levels of pharmaceuticals have been detected in waterways and effluent. Although the vast majority of releases stem from human or animal excretion and production effluent, some come from disposal practices. Studies have demonstrated numerous links between environmental exposures from pharmaceutical compounds and their impact upon aquatic life. Nurses need to be aware of this issue since their roles in health care are expanding and considered among the most trusted. Throughout the life cycle of pharmaceuticals (design, approval/regulation, production, use, and discharge/disposal), nursing can play pivotal roles in reducing and eliminating pharmaceutical waste as well as improving public safety through decreasing poisoning and drug abuse. This article discusses the environmental impact of the pharmaceutical life cycle and what roles nurses have as clinicians, educators, advocates, and researchers.
SN  - 0363-9568
AD  - Women's Health & Environmental Network, Philadelphia, Pennsylvania 19130, USA. becker.julie@gmail.com
U2  - PMID: 20838174.
DO  - 10.1097/NAQ.0b013e3181f5640a
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105007049&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105763201
T1  - Online CME: an effective alternative to face-to-face delivery.
AU  - Ryan G
AU  - Lyon P
AU  - Kumar K
AU  - Bell J
AU  - Barnet S
AU  - Shaw T
Y1  - 2007/10//
N1  - Accession Number: 105763201. Language: English. Entry Date: 20080711. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Blind Peer Reviewed; Europe; Peer Reviewed; UK & Ireland. NLM UID: 7909593. 
KW  - Accreditation -- Methods
KW  - Education, Medical, Continuing
KW  - Pharmacy and Pharmacology -- Education
KW  - Educational Measurement
KW  - Narcotics
KW  - Outcomes of Education
KW  - Pretest-Posttest Design
KW  - Student Satisfaction
KW  - Substance Dependence -- Drug Therapy
KW  - Teaching Methods
KW  - Human
SP  - e251
EP  - 7 1p
JO  - Medical Teacher
JF  - Medical Teacher
JA  - MED TEACH
VL  - 29
IS  - 8
CY  - Philadelphia, Pennsylvania
PB  - Taylor & Francis Ltd
AB  - Background: The Pharmacotherapies Accreditation Course (PAC) is a continuing medical education (CME) course designed to prepare practitioners for accreditation as pharmacotherapies prescribers for opioid dependence. The course incorporates a preparation stage, a workshop stage and a clinical placement component. The PAC continues to be successfully delivered in face-to-face mode since 2001. From 2003 onwards, an online alternative of the PAC was also implemented. Aims: The aim of this study was to evaluate the effectiveness of an online alternative to an existing face-to-face CME workshop in preparing practitioners for accreditation as a pharmacotherapies prescriber for opioid dependence. Methods: Participants were 62 practitioners who undertook the PAC between 2003 and 2006. A pretest/posttest-control group design was used, with outcome measures across the domains of knowledge, skill, and attitudes, together with a course feedback survey for both the online and face-to-face modes of the course. Results: Results demonstrate that the online CME mode was equally as effective as the face-to face mode in preparing participants for their role in the treatment and management of opioid dependence, and was also rated highly by participants. Conclusions: The findings have implications for the effective design and delivery of e-learning environments for professional practice, in terms of equipping participants with requisite clinical knowledge and skills and facilitating the development of attitudes congruent with professional practice.
SN  - 0142-159X
AD  - Faculty of Pharmacy, University of Sydney, NSW, Australia.
U2  - PMID: 18236269.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105763201&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104401795
T1  - Opinions and experiences of Indiana pharmacists and student pharmacists: The need for addiction and substance abuse education in the United States.
AU  - Wenthur CJ
AU  - Cross BS
AU  - Vernon VP
AU  - Shelly JL
AU  - Harth BN
AU  - Lienhoop AD
AU  - Madison NR
AU  - Murawski MM
Y1  - 2013/01//
N1  - Accession Number: 104401795. Language: English. Entry Date: 20130531. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 101231974. 
KW  - Education, Pharmacy -- Administration
KW  - Pharmacists -- Psychosocial Factors
KW  - Students, Pharmacy -- Psychosocial Factors
KW  - Substance Use Disorders
KW  - Attitude of Health Personnel
KW  - Curriculum
KW  - Human
KW  - Indiana
KW  - Pharmacists -- Administration
KW  - Professional Role
KW  - Questionnaires
KW  - United States
SP  - 90
EP  - 100 11p
JO  - Research in Social & Administrative Pharmacy
JF  - Research in Social & Administrative Pharmacy
JA  - RES SOCIAL ADM PHARM
VL  - 9
IS  - 1
CY  - New York, New York
PB  - Elsevier Science
SN  - 1551-7411
AD  - Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, USA.
U2  - PMID: 22695219.
DO  - 10.1016/j.sapharm.2012.03.003
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104401795&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107287656
T1  - Optimizing smoking cessation strategies.
AU  - Andrews J
Y1  - 1998/08//1998 Aug
N1  - Accession Number: 107287656. Language: English. Entry Date: 19981001. Revision Date: 20150819. Publication Type: Journal Article; algorithm; consumer/patient teaching materials; questionnaire/scale; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 7603663. 
KW  - Smoking Cessation
KW  - Preventive Health Care
KW  - Smoking -- Complications
KW  - Smoking -- Psychosocial Factors
KW  - Smoking -- Drug Therapy
KW  - Drug Interactions
KW  - Clinical Assessment Tools
KW  - Substance Dependence -- Diagnosis
KW  - Patient Education
SP  - 47
EP  - 58 6p
JO  - Nurse Practitioner
JF  - Nurse Practitioner
JA  - NURSE PRACT
VL  - 23
IS  - 8
CY  - Philadelphia, Pennsylvania
PB  - Springhouse Corporation
AB  - Smoking cigarettes remains the leading cause of preventable illnesses and premature deaths in the United States. Although approximately half of living Americans who have ever smoked have quit, recent studies show that more than 70% of current smokers would like to stop smoking. Health care providers can enhance smoking cessation in their clients by performing assessments of both the physical and psychologic addictive aspects of smoking as well as past and current cessation barriers. Based on the assessment, the clinician should formulate a treatment plan by individualizing appropriate education, counseling, motivation, and pharmacologic support. This article reviews the prevalence and hazards of smoking and supplies health care providers with interventions to assist clients in becoming and remaining nonsmokers.
SN  - 0361-1817
AD  - Primary Care Nurse Practitioner, Department of Veterans Affairs, Augusta, Ga
U2  - PMID: 9718601.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107287656&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105080840
T1  - Outcomes associated with transdermal nicotine replacement therapy in a neurosurgery intensive care unit.
AU  - Panos NG
AU  - Tesoro EP
AU  - Kim KS
AU  - Mucksavage JJ
Y1  - 2010/08/15/
N1  - Accession Number: 105080840. Language: English. Entry Date: 20100903. Revision Date: 20150711. Publication Type: Journal Article; clinical trial; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Administration, Topical
KW  - Neurosurgery
KW  - Nicotine -- Administration and Dosage
KW  - Adult
KW  - Chi Square Test
KW  - Clinical Trials
KW  - Descriptive Statistics
KW  - Female
KW  - Hemorrhage
KW  - Human
KW  - Intensive Care Units
KW  - Length of Stay
KW  - Male
KW  - Middle Age
KW  - Mortality
KW  - Pearson's Correlation Coefficient
KW  - Post Hoc Analysis
KW  - Record Review
KW  - Retrospective Design
KW  - Smoking
KW  - Stroke
KW  - T-Tests
KW  - Treatment Outcomes
SP  - 1357
EP  - 1361 5p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 67
IS  - 16
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
AB  - PURPOSE: The outcomes associated with transdermal nicotine replacement therapy (NRT) in a neurosurgery intensive care unit (ICU) were studied. METHODS: Data from pharmacy records, neurosurgery ICU admission logs, and computerized patient charts at the University of Illinois Medical Center at Chicago from January 2001 through August 2008 were reviewed for patients older than 18 years who were admitted to the neurosurgery ICU for neurologic insults. Patients were categorized into three groups: smokers who received transdermal NRT (n = 114), smokers who did not receive transdermal NRT (n = 113), and nonsmokers (n = 113). The primary outcome of this study was unfavorable disposition at discharge from the hospital. Secondary outcomes measured included overall mortality; lengths of hospital and neurosurgery ICU stays; and rates of subarachnoid hemorrhage (SAH) rebleeding, angiographic vasospasm, intracerebral hemorrhage rebleeding, and ischemic stroke. RESULTS: Overall, there was no difference in unfavorable discharge disposition among the three groups (p = 0.17). However, the group who received NRT had higher admission rates of SAH, smoked more cigarettes for a longer period of time, and had longer stays in the neurosurgery ICU and hospital compared with the other groups. All patients who received NRT had prolonged hospital (p = 0.014) and neurosurgery ICU (p = 0.006) stays compared with those who did not receive NRT. There were no differences in other secondary outcomes among the groups. CONCLUSION: There was no significant difference in unfavorable discharge disposition among neurosurgery ICU patients who were smokers treated with NRT, smokers not treated with NRT, and nonsmokers not treated with NRT.
SN  - 1079-2082
AD  - Department of Pharmacy Services, Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA. npanos@lumc.edu
U2  - PMID: 20689126.
DO  - 10.2146/ajhp090402
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105940004
T1  - Outpatient treatment programs: a review article on substances of abuse outpatients treatment outcomes in the United States.
AU  - Nsimba SED
Y1  - 2007/09//2007 Sep
N1  - Accession Number: 105940004. Language: English. Entry Date: 20080125. Revision Date: 20150711. Publication Type: Journal Article; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Psychiatry/Psychology. NLM UID: 101148822. 
KW  - Outpatients
KW  - Substance Abuse -- Therapy
KW  - Health Care Costs
KW  - Substance Abuse -- Drug Therapy
KW  - Treatment Duration
KW  - Treatment Outcomes
KW  - United States
SP  - 91
EP  - 99 9p
JO  - Addictive Disorders & Their Treatment
JF  - Addictive Disorders & Their Treatment
JA  - ADDICT DISORD THEIR TREAT
VL  - 6
IS  - 3
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - A number of treatment approaches and techniques have been developed and used for management of drug abuse and alcoholism during the last 50 years in the United States. These treatment methods have been categorized based on the treatment settings (outpatient, short-term residential, long-term residential) or based on treatment techniques [pharmacological or nonpharmacological (behavioral, psychosocial)]. The relative effectiveness and appropriateness of these treatments has always been an issue of concern to health policy, and decision makers, treatment providers and the users. For example, naltrexone, a long acting orally effective opioid antagonist, has been tried in patients of opioid or alcohol dependence. In controlled clinical studies, the drug has shown positive effects when added to counseling. It is reported to significantly reduce heavy drinking in patients who are willing to take the drug as prescribed. However, the beneficial effects of naltrexone are limited due to the serious problem of noncompliance or lack of willingness of patients to continue it for sufficient duration. Buprenorphine is an opioid agonist-antagonist effective for the treatment of opiate abuse besides its analgesic indication in patients with advanced painful cancer. Three national studies evaluating drug abuse treatment programs have been carried out to evaluate the suitability of the different outpatient treatment programs. However, methodological differences used in these programs have been a limitation to arrive at solid conclusions. Furthermore, the treatment modalities also varied as they evolved across time and change in their components. The client characteristics changed across last 3 decades particularly regarding the drug of abuse. The admission to specific treatment modalities depended on client criteria based on admission guidelines in force from time to time. These variations may limit the comparability of treatment outcome across these studies and across different treatment modalities, though adequate measures have been taken during analysis to minimize these limitations. Despite these limitations, some generalizations about the effectiveness of outpatient treatment can be made from the findings that have been consistent across studies. Outpatient drug-free treatment program is effective in reducing drug abuse and in improving other parameters like criminality and employment. Furthermore, it is effective as methadone maintenance; however, it is less effective than long-term residential treatment program. The program is effective primarily if patients receive treatment for 3 months or longer.
SN  - 1531-5754
AD  - Department of Clinical Pharmacology, Muhimbili University College of Health Sciences (MUCHS), PO Box 65010, Dar-es-Salaam, Tanzania, East Africa; nsimbastephen@yahoo.co.uk.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105940004&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105372306
T1  - Overcoming barriers to osteoporosis care in vulnerable elderly patients with hip fractures.
AU  - Switzer JA
AU  - Jaglal S
AU  - Bogoch ER
Y1  - 2009/07//2009 Jul
N1  - Accession Number: 105372306. Language: English. Entry Date: 20090918. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Allied Health; Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Evidence-Based Practice; Physical Therapy. NLM UID: 8807705. 
KW  - Geriatric Assessment -- Methods
KW  - Hip Fractures -- Diagnosis
KW  - Hip Fractures -- Therapy
KW  - Medical Practice, Evidence-Based
KW  - Osteoporosis -- Diagnosis
KW  - Osteoporosis -- Therapy
KW  - Aged
KW  - Aged, 80 and Over
KW  - Female
KW  - Hip Fractures -- Complications
KW  - Male
KW  - Osteoporosis -- Complications
KW  - Risk Assessment
SP  - 454
EP  - 459 6p
JO  - Journal of Orthopaedic Trauma
JF  - Journal of Orthopaedic Trauma
JA  - J ORTHOP TRAUMA
VL  - 23
IS  - 6
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - Indications for and benefits of providing osteoporosis (OP) care for hip fracture patients have become widely understood. The hip fracture patient is frequently over age 80 years, minimally ambulatory, has multiple medical comorbidities, and has cognitive impairment. Patient barriers to initiation of effective OP treatment include: age, dementia, medical comorbidities, polypharmacy, lack of adherence with treatment, alcohol abuse, postoperative delirium, language barriers, inadequate social support, and socioeconomic status. In a large teaching hospital, 244 patients presented with hip fracture over 2 years: 72% were female and 64% were over age 80. Forty percent had been diagnosed with dementia; another 29% had other severe medical comorbidities.Opportunities for OP diagnosis and treatment are numerous. In acute care hospitals, coordinator facilitated programs are effective for identification, education, assessment, referral, and treatment of underlying OP in fracture patients. System modifications may include an automated care path or automatic specialist referral for hip fracture patients. In the rehabilitation hospital, the patients are in a more stable condition, there is a focus on the recent fracture, and there are opportunities to initiate OP treatment and to promote adherence. In long-term care, dietary intake including calcium and vitamin D supplementation and persistence with pharmacotherapy can be monitored. Patient education and referral to the family physician for osteoporosis investigation and treatment have improved patient knowledge and diagnosis, but the reported impact on treatment has been limited.Effective OP care for the vulnerable hip fracture patient should be initiated early but may be complex and require coordination. In addition to calcium and vitamin D supplementation, most patients in this category have an indication for aminobisphosphonate therapy. Liaison between the orthopaedic team and the discharge destination caregivers, an established discharge diagnosis of osteoporosis, and ensuring patients are discharged on supplements and medication will promote patient, caregiver, and primary care physician awareness of the patient's OP care needs. Education programs may provide benefits at later stages, to improve adherence with treatment.
SN  - 0890-5339
AD  - Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN 55101, USA. julie.a.switzer@healthpartners.com
U2  - PMID: 19550234.
DO  - 10.1097/BOT.0b013e31815e92d2
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105372306&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105039127
T1  - Pain management and the U.S. Department of Justice.
AU  - Garrison K
AU  - Mitty E
Y1  - 2010/05//May/Jun2010
N1  - Accession Number: 105039127. Language: English. Entry Date: 20100813. Revision Date: 20150818. Publication Type: Journal Article. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Special Interest: Gerontologic Care; Pain and Pain Management. NLM UID: 8309633. 
KW  - Drug and Narcotic Control -- Legislation and Jurisprudence -- United States
KW  - Drug Enforcement Administration
KW  - Long Term Care
KW  - Pain -- Drug Therapy
KW  - Substance Abuse -- Prevention and Control
KW  - Analgesics, Opioid -- Classification
KW  - Legislation
KW  - Pharmacy, Retail
KW  - Prescriptions, Drug
KW  - United States
SP  - 214
EP  - 219 6p
JO  - Geriatric Nursing
JF  - Geriatric Nursing
JA  - GERIATR NURS
VL  - 31
IS  - 3
CY  - New York, New York
PB  - Elsevier Science
AB  - The Drug Enforcement Agency (DEA) may be restricting the ability of RNs and LPNs in assisted living communities (ALCs) in some states to provide pain relief for residents. The DEAs enforcement of the requirements of the Controlled Substances Act (CSA) to reduce diversion of controlled substances (particularly Schedule II meds) for criminal or nefarious reasons, has generated a variety of responses by pharmacies, ALCs, and practitioners. Residents are at risk for--and some residents have already experienced--inadequate pain management. The argument seems to turn on whether an ALC (or nursing home or home health nurse) is an 'agent' of the physician. The term 'agent' is poorly defined in section 1300 of the CSA. It neither confirms that an ALC/long-term care (LTC) nurse/medical aide may function as an agent of the provider nor does the definition preclude the ALC/LTC nurse/medical aide as the agent of the provider. This article is an alert to ALCs to examine their controlled drug procurement and pain management procedures and is also a call to advocacy by ALC nurses.
SN  - 0197-4572
AD  - Elite Elder Care, Portland, OR
U2  - PMID: 20525527.
DO  - 10.1016/j.gerinurse.2010.04.004
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105039127&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103794070
T1  - Palliative Care in Latin America from the Professional Perspective: A SWOT Analysis.
AU  - Pastrana, Tania
AU  - Centeno, Carlos
AU  - De Lima, Liliana
Y1  - 2015/05//
N1  - Accession Number: 103794070. Language: English. Entry Date: 20150430. Revision Date: 20150710. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Palliative Care/Hospice. Grant Information: This work was funded by the Open Society Foundations and in cooperation with the International Association for Hospice and Palliative Care (IAHPC), the European Association for Palliative Care (EAPC), the Sociedad Espanola de Cuidados Paliativos (SECPAL), and the ATLANTES Research Program of the Institute for Culture and Society (ICS) at the Universidad de Navarra.. NLM UID: 9808462. 
KW  - Palliative Care -- Statistics and Numerical Data -- Latin America
KW  - Attitude of Health Personnel -- Evaluation
KW  - Latin America
KW  - Human
KW  - Content Analysis
KW  - Expert Clinicians
KW  - Survey Research
KW  - Descriptive Statistics
KW  - Data Analysis Software
KW  - Correlational Studies
KW  - Semi-Structured Interview
KW  - Funding Source
SP  - 429
EP  - 437 9p
JO  - Journal of Palliative Medicine
JF  - Journal of Palliative Medicine
JA  - J PALLIAT MED
VL  - 18
IS  - 5
CY  - New Rochelle, New York
PB  - Mary Ann Liebert, Inc.
AB  - Background: The development of palliative care (PC) in Latin America (LA) has been slow compared to other regions. A Strengths, Weaknesses, Opportunities, and Threats (SWOT) analysis may contribute to the identification of barriers and successful strategies. Objective: The study's objective was to conduct a SWOT analysis of the development of PC in LA from the PC professional perspective. Methods: Experts from 19 countries of the region were selected in collaboration with national associations. Specific questions were included in the Latin American Association for Palliative Care (ALCP) Atlas of Palliative Care cross-survey 2012. Content analysis was conducted categorizing responses in a SWOT framework. Descriptive and correlation analyses were performed. Results: A total of 577 statements were provided. Among the Strengths were integration into health systems and increasing number of professionals with PC training. Among weaknesses were lack of national PC programs, limited connection between policymakers and professionals, and barriers in the availability of opioids. Opportunities were increased awareness of policymakers and higher interest of students and professionals. Threats were competing funding for other services and medications, limited interest of the pharmaceutical industry in producing affordable opioid medications, and emphasis by the media on opioid diversion and abuse. Comments were categorized under (1) health policy, (2) education and research, (3) service provision, (4) opioid availability, and (5) advocacy. A moderately positive correlation was found (R=0.4 in both) between the ALCP development index7 and the number of positive/negative factors mentioned by country. Conclusions: A SWOT framework is applicable in a situational analysis and helps to identify common aspects among the countries and key elements in the development of PC in Latin America.
SN  - 1096-6218
AD  - Department of Palliative Medicine, RWTH Aachen University, Aachen, Germany.
AD  - ATLANTES Research Program, Institute for Culture and Society, University of Navarra, Pamplona (Navarra), Spain.
AD  - International Association for Hospice and Palliative Care, Houston, Texas.
U2  - PMID: 25658701.
DO  - 10.1089/jpm.2014.0120
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107289869
T1  - Patient consultation in a managed care setting: guiding pharmacy into the future.
AU  - Foster SL
AU  - Smith EB
Y1  - 1998/07//1998 Jul
N1  - Accession Number: 107289869. Language: English. Entry Date: 19981001. Revision Date: 20150711. Publication Type: Journal Article; CEU; exam questions; tables/charts. Journal Subset: Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Health Services Administration; Peer Reviewed; USA. NLM UID: 9613960. 
KW  - Managed Care Programs -- Trends
KW  - Pharmacy and Pharmacology -- Trends
KW  - Patient Education -- Trends
KW  - Strategic Planning
KW  - Education, Continuing (Credit)
KW  - Patient Compliance
KW  - Drug Therapy -- Adverse Effects
KW  - Patient Selection
KW  - Documentation
SP  - 1039
EP  - 1048 10p
JO  - American Journal of Managed Care
JF  - American Journal of Managed Care
JA  - AM J MANAGE CARE
VL  - 4
IS  - 7
CY  - Plainsboro, New Jersey
PB  - Intellisphere, LLC
AB  - Managed care organizations are excellent environments for pharmaceutical care programs to demonstrate their impact on patient care outcomes and to decrease costs. Patient consultation is the cornerstone in implementing pharmaceutical care because it increases patient contact with the pharmacists while improving patient compliance with drug therapy (adherence). Implementation of a patient consultation program that verifies patients' understanding of their disease and therapy gives the pharmacist information necessary to monitor drug therapy. Use of strategic planning to overcome barriers, followed by the development of local standards of practice, will refocus the practice philosophy to one of improving patient outcomes. Pharmacy managers must demonstrate and document the value that patient consultation brings to the patient and the healthcare system. Then, they must integrate their counseling effort with other health education efforts of the managed care system. Pharmacists will gain the support of other disciplines by reinforcing their efforts. Together they can work to decrease the problems that are inherent with drug therapy. These goals can be accomplished with minimal expense and have the potential to produce significant savings in healthcare costs.
SN  - 1088-0224
AD  - Department of Pharmacy Practice and Pharmacoeconomics, University of Tennessee College of Pharmacy, 847 Monroe Avenue, Memphis, TN 38163
U2  - PMID: 10181993.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107289869&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105610763
T1  - Patient education and self-advocacy: queries and responses on pain management.
AU  - Farahmand N
AU  - Drennan D
Y1  - 2008/12//
N1  - Accession Number: 105610763. Language: English. Entry Date: 20090320. Revision Date: 20150711. Publication Type: Journal Article; questions and answers. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Pain and Pain Management; Palliative Care/Hospice. NLM UID: 101125608. 
KW  - Caffeine -- Adverse Effects
KW  - Chronic Pain -- Drug Therapy
KW  - Headache -- Etiology
KW  - Methadone -- Adverse Effects
KW  - Beverages -- Analysis
KW  - Caffeine -- Analysis
KW  - Patient Education
KW  - Substance Withdrawal Syndrome
SP  - 312
EP  - 314 3p
JO  - Journal of Pain & Palliative Care Pharmacotherapy
JF  - Journal of Pain & Palliative Care Pharmacotherapy
JA  - J PAIN PALLIAT CARE PHARMACOTHER
VL  - 22
IS  - 4
PB  - Taylor & Francis Ltd
AB  - Questions from patients about analgesic pharmacotherapy and responses from the authors are presented to help educate patient sand make them more effective self-advocates. The topics addressed in this issue are headaches and their relation to caffeine intake, methadone-associated sleep and breathing disorders, and risks and benefits of chronic pain treatment.
SN  - 1536-0288
AD  - Anesthesiology Pain Management Fellows at the University Health Care Pain Management Center, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 112859290
T1  - Patient-Centered Pharmacy Services: A Descriptive Report.
AU  - McKain, Melanie
AU  - O'Neil, Christine K
Y1  - 2015/11//
N1  - Accession Number: 112859290. Language: English. Entry Date: In Process. Revision Date: 20160210. Publication Type: journal article. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9013983. 
SP  - 664
EP  - 670 7p
JO  - Consultant Pharmacist
JF  - Consultant Pharmacist
JA  - CONSULTANT PHARMACIST
VL  - 30
IS  - 11
CY  - Alexandria, Virginia
PB  - American Society of Consultant Pharmacists
AB  - This paper describes a proactive, patient-centered, interprofessional approach to medication review in a long-term care facility. Clinical pharmacy services were provided to residents in multiple high-risk areas including transition of care; medication reconciliation; monitoring of infectious disease, pain, anticoagulation, psychotropic drugs, and falls; and requested consults for any change in condition. Process outcomes were evaluated, specifically the number of patients reviewed, number and type of recommendations made, and acceptance rate of recommendations by physicians; 1,333 medication regimen reviews were conducted. A total of 274 recommendations were made, and 56 recommendations were excluded as "lost to follow-up" because the recommendation was not acknowledged by the physician. Of the 218 acknowledged recommendations, 157 (72%) were accepted. Collective workload statistics suggest that the service identified and eliminated potential drugrelated problems such as inappropriate medications, drug interactions, and discrepancies during medication reconciliation. The large number of reviews conducted in a short time period show that there is a need for regular pharmacist review.
SN  - 0888-5109
AD  - Duquesne University-Mylan School of Pharmacy, Pittsburgh, Pennsylvania, USA
U2  - PMID: 26629802.
DO  - 10.4140/TCP.n.2015.664
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106625747
T1  - Patients with chronic asthma found medicine information to be unclear or confusing, did not receive complete information on medicine use and side effects, and found leaflets to be unhelpful.
AU  - Hartig MT
Y1  - 2005/01//
N1  - Accession Number: 106625747. Language: English. Entry Date: 20050506. Revision Date: 20150820. Publication Type: Journal Article; abstract; commentary. Original Study: Raynor DK, Savage I, Knapp P, Henley J. We are the experts: people with asthma talk about their medicine information needs. (PATIENT EDUC COUNS) May2004; 53 (2): 167-174. Journal Subset: Core Nursing; Europe; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 9815947. 
KW  - Asthma -- Drug Therapy
KW  - Asthma -- Education
KW  - Information Needs
KW  - Patient Attitudes
KW  - Patient Education
KW  - Adolescence
KW  - Adult
KW  - Aged
KW  - Aged, 80 and Over
KW  - Drug Information
KW  - Drug Therapy -- Education
KW  - Female
KW  - Focus Groups
KW  - Male
KW  - Middle Age
KW  - Qualitative Studies
KW  - Teaching Materials
KW  - Thematic Analysis
KW  - United Kingdom
SP  - 28
EP  - 28 1p
JO  - Evidence Based Nursing
JF  - Evidence Based Nursing
JA  - EVID BASED NURS
VL  - 8
IS  - 1
PB  - BMJ Publishing Group
AB  - What are the medication related experiences and perceptions of patients with chronic asthma? What are their views on mandatory leaflets provided by drug manufacturers?DESIGNQualitative study.SETTING6 community pharmacies in Leeds, UK.PATIENTS23 patients (age range 13--82 y, 52% women) with asthma (duration 3 to >40 y).METHODSPatients participated in 1 of four 90 minute focus groups. After describing their medication related experiences, patients were asked to comment on 5 leaflets about asthma medicine (reliever and preventer inhalers, generic and branded broad spectrum antibiotics, and a generic oral steroid). Audiotapes were transcribed verbatim, and themes and categories were generated.MAIN FINDINGS10 themes were identified. (1) Information experiences. Almost half of the patients felt that the information they received met their needs and helped them to feel in control of their symptoms. The remainder felt that the information given was unclear or confusing or that information was wanted but not given. Patients identified 5 information needs: name and purpose of treatment; when, how, and how long to take it; side effects and what to do about them; problems with other drugs; and how to tell if the medicine is not working. (2) Although most patients knew the name and purpose of their medicine, some were not told, or did not understand, what their medicines were. (3) When and how to take it. Most participants received good information on how to use inhalers from nurses. About 1/3 received no information from their healthcare provider on inhaler use when they were first diagnosed. During acute attacks, patients noted the differences between 'ideal' inhaler techniques and what they actually did without previous guidance. (4) Side effects and what to do about them. Patients obtained information on short term side effects from self observation or family and friends but obtained information on long term side effects from magazines, books, manufacturers' leaflets, and nurses and GPs. Most patients felt that information on side effects was not freely provided. (5) Information on problems with other medicines was obtained from community pharmacists, and experiences were mainly positive. Some tension existed between official advice on contraindications and patients' experiences. (6) Is this the right medicine for me? Most patients knew about the many asthma medicines available but were unsure about their physicians' awareness of new treatments. Many were unclear about how physicians decided to use a particular medicine and why a medicine was the right one for them. (7) What people do to get information. Primary care providers were patients' main information source. Physicians provided information on initiating treatment; nurses provided more detailed and customised instructions on inhaler use and peak flow monitoring; and pharmacists provided information on medication interactions. (8) The place of written information. Written information was rarely mentioned without prompting. Patients preferred one to one information giving because information could be individualised to their needs and abilities. Patients often threw away leaflets because they looked unimportant, there was too much to read, the appearance was boring with small type, and they thought that inhaler technique was not best learnt by reading about it. (9) Patients believed that they should be involved in developing leaflets. Some patients viewed personal experience as more important than manufacturers' leaflets and believed that leaflets should be tested on patients. (10) Manufacturers: trust and priorities. Patients felt that the primary purpose of leaflets was to provide insurance for manufacturers against potential problems and to help sell products.CONCLUSIONSPatients' unsatisfactory experiences with information about asthma medicine included unclear or confusing information and no individualised, personally relevant information. They preferred personal contacts rather than written sources. Most felt that nurses and physicians did not freely provide information on side effects, and they did not find manufacturers' leaflets useful.
SN  - 1367-6539
AD  - University of Tennessee Health Science Center, College of Nursing, Memphis, TN
U2  - PMID: 15688502.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108301498
T1  - Pattern of drug therapy problems and interventions in ambulatory patients receiving antiretroviral therapy in Nigeria.
AU  - OJEH, Victor B.
AU  - NAIMA, Nasir
AU  - ABAH, Isaac O.
AU  - FALANG, Kakjing D.
AU  - LUCY, Ogwuche
AU  - LONDON, Ibrahim
AU  - DADY, Christiana
AU  - AGABA, Patricia
AU  - AGBAJI, Oche
Y1  - 2015/04//Apr-Jun2015
N1  - Accession Number: 108301498. Language: English. Entry Date: In Process. Revision Date: 20150812. Publication Type: Article. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. 
SP  - 1
EP  - 6 6p
JO  - Pharmacy Practice (18863655)
JF  - Pharmacy Practice (18863655)
JA  - PHARM PRACT
VL  - 13
IS  - 2
PB  - Centro de Investigaciones y Publicaciones Farmaceuticas S.L.
AB  - Objectives: We describe the frequency and types of drug therapy problems (DTPs), and interventions carried out to resolve them, among a cohort of HIV- infected patients on ART in Jos, Nigeria. Methods: A prospective pharmacists' intervention study was conducted between January and August 2012 at the outpatient HIV clinic of the Jos University Teaching Hospital (JUTH). Pharmacists identified DTPs and made recommendations to resolve them. The main outcome measures were number of DTPs encountered, interventions proposed and acceptance rate of recommendations. Results: A total of 42,416 prescriptions were dispensed to 9339 patients during the eight months study. A total of 420 interventions (Intervention rate of 1 per 100 prescriptions) were made to resolve DTPs in 401 (4.3%) patients with a mean age of 41 (SD=10) years, and made up of 73% females. DTPs encountered were drug omission (n=89, 21.2%), unnecessary drug (n=55, 13.1%) and wrong drug indication (n=55, 13.1%). Recommendations offered included; Addition of another drug to the therapy (n=87, 20.7%), rectification of incomplete prescriptions (n=85, 20.2%), change of drug or dosage (n=67, 16.0%), and discontinuation of the offending drug (n=59, 14.0%). A total of 389 (93%) out of 420 of the recommendations were accepted. In all, 50.4% (212) of the problematic prescriptions were changed and dispensed, 22.2% (89) were clarified and dispensed, while wrong identities were corrected in 11.7% (49). However, 7.5% (30) prescriptions were dispensed as prescribed, 5.2% (21) were not dispensed, and 3% (12) were unresolved. Conclusion: Our findings suggest that pharmacistsinitiated interventions can ameliorate DTPs in patients receiving ART given the high intervention acceptance rate recorded. The implication of this finding is that pharmacists with requisite training in HIV pharmacotherapy are an excellent resource in detecting and minimizing the effect of antiretroviral drug-related errors.
AB  - Objetivos: Describimos la frecuencia y los tipos de problemas relacionados con medicamentos (DTP) y las intervenciones realizadas para resolverlos en una cohorte de pacientes infectados con HIV a tratamiento con antirretrovirales (ART). Métodos: Se realizó un estudio prospectivo de intervención farmacéutica entre enero y agosto de 2012 en la consulta ambulatoria de HIV del Hospital Universitario de Jos (JUTH). Los farmacéuticos identificaban DTP e hicieron las recomendaciones para resolverlos. Los outcomes principales fueron el número de DTP encontrados, las intervenciones propuestas y la tasa de aceptación de las recomendaciones. Resultados: Se dispensó un total de 42.416 recetas a 9.339 pacientes durante los 8 meses del estudio. Se realizaron un total de 420 intervenciones (tasa de intervención de 1 por 100 recetas) para resolver los DTP de 401 (4,3%) pacientes con una media de edad de 41 (DE=10) años, de los que el 73% eran mujeres. Los DTP encontrados fueron omisión de medicamento (n=89; 21,2%), seguido de medicamento innecesario (n=55; 13,1%) e indicación terapéutica errónea (n=55; 13,1%). Las recomendaciones ofrecidas incluyeron: Adición de otro medicamento al tratamiento (n=87; 20,7%), rectificación de receta incompleta (n=85; 20,2%), cambio de medicamento o dosis (n=67; 16,0%), y discontinuación de medicamento problemático (n=59; 14,0%). Un total e 389 (93%) de las 420recomendacioens fueron aceptadas. En total, el 50,4% (212) de los medicamentos problemáticos fueron cambiados y dispensados, el 22,2% (89) fueron aclarados y dispensados, mientras que se corrigieron identidades erróneas en el 11,7% (49). Sin embargo, el 7,5% de las recetas fueron dispensadas como fueron prescritas, el 5,2% (21) no fue dispensada, y el 3% (12) quedó sin resolver. Conclusión: Nuestro resultados sugieren que las intervenciones farmacéuticas pueden mejorar los DTP en pacientes que reciben ART, dada la alta aceptación registrada. La implicación de este hallazgo es que los farmacéuticos con entrenamiento en terapéutica para HIV son un recurso excelente para detectar y minimizar el efecto de los errores de los antirretrovirales.
SN  - 1886-3655
AD  - Principal Pharmacist. APIN Centre/Pharmacy Department, Jos University Teaching Hospital. Jos, Nigeria
AD  - Pharmacist. APIN Centre/Pharmacy Department, Jos University Teaching Hospital. Jos, Nigeria
AD  - Assistant Director of Pharmaceutical Services. APIN Centre/Pharmacy Department, Jos University Teaching Hospital. Jos, Nigeria
AD  - Senior Lecturer. Department of Pharmacology, University of Jos. Jos, Nigeria
AD  - Consultant Family Physician. Department of Family Medicine, University of Jos. Jos, Nigeria
AD  - Consultant Nephrologist. Nephrology Unit, Department of Internal Medicine, University of Jos. Jos, Nigeria
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106313867
T1  - Patterns of HIV prevalence and HIV risk behaviors among injection drug users prior to and 24 months following implementation of cross-border HIV prevention interventions in northern Vietnam and southern China.
AU  - Hammett TM
AU  - Kling R
AU  - Johnston P
AU  - Liu W
AU  - Ngu D
AU  - Friedmann P
AU  - Binh KT
AU  - Dong HV
AU  - Van LK
AU  - Donghua M
AU  - Chen Y
AU  - Des Jarlais DC
Y1  - 2006/04//
N1  - Accession Number: 106313867. Language: English. Entry Date: 20060811. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Health Promotion/Education; Peer Reviewed; USA. NLM UID: 9002873. 
KW  - HIV Infections -- Epidemiology
KW  - Preventive Health Care -- Methods
KW  - Substance Abuse, Intravenous -- Epidemiology
KW  - Adult
KW  - Business
KW  - Causal Attribution
KW  - China
KW  - Comorbidity
KW  - Comparative Studies
KW  - Cross Sectional Studies
KW  - Descriptive Statistics
KW  - Emigration and Immigration
KW  - Ethnic Groups
KW  - Female
KW  - Interviews
KW  - Logistic Regression
KW  - Male
KW  - Marital Status
KW  - Prevalence
KW  - Risk Taking Behavior
KW  - Snowball Sample
KW  - Surveys
KW  - Vietnam
KW  - Human
SP  - 97
EP  - 115 19p
JO  - AIDS Education & Prevention
JF  - AIDS Education & Prevention
JA  - AIDS EDUC PREV
VL  - 18
IS  - 2
CY  - New York, New York
PB  - Guilford Publications Inc.
AB  - In 2002, we implemented a 4-year HIV prevention intervention for injection drug users (IDUs) in Lang Son Province, Vietnam, and Ning Ming County, Guangxi Province, China, a cross-border region seriously affected by inter-twined epidemics of heroin injection and HIV infection. The interventions involve peer education on HIV risk reduction and provision of new needles/syringes through direct distribution and pharmacy vouchers. We consider this to be a structural intervention in which risk reduction information and sterile injection equipment are diffused through the IDU populations and not limited to those who actually interact with peer educators. The evaluation of structural interventions poses complex methodological challenges. The evaluation of our interventions relies primarily on cross-sectional surveys (interviews and HIV testing) of samples of IDUs selected using a combination of targeted cluster and snowball methods. We consider this to be an appropriate, albeit imperfect, design given the study context. This paper presents analyses of data from the IDU surveys conducted just prior to implementation of the interventions and 24 months thereafter. The cross-border interventions have reached large proportions of the IDUs in the project sites, drug-related HIV risk behaviors have declined in frequency, and HIV prevalence among IDUs has been stable in China and declined in Vietnam over the 24 months since the interventions were implemented. Attribution of these positive trends to the interventions must be qualified in light of possible sampling biases and the absence of control groups. However, we believe that the structural interventions implemented by the cross-border project have played a role in stabilizing HIV prevalence among IDUs two years after they were initiated. Evidence of further diffusion of the interventions among IDUs and continued stability or decline of HIV prevalence would strengthen this case.
SN  - 0899-9546
AD  - Abt Associates Inc., Cambridge, MA 02138, USA. red_hammett@abtassoc.com
U2  - PMID: 16649956.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106467555
T1  - Patterns of use and harm reduction practices of ecstasy users in Australia.
AU  - Allott K
AU  - Redman J
Y1  - 2006/04/28/
N1  - Accession Number: 106467555. Language: English. Entry Date: 20060707. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology. NLM UID: 7513587. 
KW  - Harm Reduction
KW  - Methylenedioxymethamphetamine
KW  - Substance Abusers
KW  - Adult
KW  - Age Factors
KW  - Australia
KW  - Chi Square Test
KW  - Convenience Sample
KW  - Data Analysis Software
KW  - Descriptive Statistics
KW  - Exploratory Research
KW  - Female
KW  - Male
KW  - Prevalence
KW  - Questionnaires
KW  - Sex Factors
KW  - Snowball Sample
KW  - Substance Abuse -- Epidemiology
KW  - T-Tests
KW  - Human
SP  - 168
EP  - 176 9p
JO  - Drug & Alcohol Dependence
JF  - Drug & Alcohol Dependence
JA  - DRUG ALCOHOL DEPENDENCE
VL  - 82
IS  - 2
PB  - Elsevier Science
AB  - Harm reduction refers to the use of strategies to prevent or reduce harmful consequences associated with illicit drug use. There is a paucity of research concerning the harm reduction practices employed by ecstasy users. This study aimed to explore the prevalence, nature and factors associated with harm reduction practices employed by ecstasy users in Australia, with a specific focus on the practice of preloading and postloading-the use of pharmaceuticals and natural products prior and subsequent to ecstasy use. One hundred and sixteen Australian residents aged 18 years and over who had used ecstasy at least once in their lifetime were recruited via convenience sampling, 'snowballing' and via web-based advertisements and completed an anonymous questionnaire. Participants reported using a wide range of strategies for minimising ecstasy-associated harm. The most common strategies used for reducing negative side effects, 'comedown' or neurotoxicity were drinking water, limiting or reducing ecstasy use, taking breaks and taking vitamins or other natural substances. Forty percent of the sample had tested their ecstasy pills for the presence of MDMA. Forty-one percent and 47% of participants had engaged in pre- and postloading, respectively, with the most common pre- and postloading substances being multivitamins, 5-HTP, magnesium and fruit or fruit juice. Younger mean age and 'high' total occasions of ecstasy use was significantly associated with preloading, and 'high' total use and frequency of use was associated with postloading. The results indicate that ecstasy users are aware of the potential for harm associated with ecstasy use and attempt to minimise harm by actively employing strategies. By exploring the pattern of harm reduction practices among ecstasy users, this study has highlighted the need for further research into the efficacy and potential clinical drug interactions associated with such practices, as well as the need for investigation of how such practices may affect patterns of ecstasy use.
SN  - 0376-8716
AD  - Department of Psychology, Monash University, Vic. 3800, Australia.
U2  - PMID: 16226850.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105889202
T1  - PDA-based documentation of medication interventions in an ambulatory care setting.
AU  - Fit KE
AU  - Burkiewicz JS
AU  - Sweeney BL
Y1  - 2007/01//2007 Jan-Feb
N1  - Accession Number: 105889202. Language: English. Entry Date: 20080418. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Double Blind Peer Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Public Health. NLM UID: 8504643. 
KW  - Computerized Patient Record
KW  - Computers, Hand-Held
KW  - Outpatients
KW  - Aged
KW  - Data Analysis Software
KW  - Descriptive Statistics
KW  - Female
KW  - Logistic Regression
KW  - Male
KW  - Medication Errors -- Prevention and Control
KW  - Middle Age
KW  - Multivariate Analysis
KW  - Physician Attitudes
KW  - Prescribing Patterns
KW  - Human
SP  - 9
EP  - 15 7p
JO  - Journal of Pharmacy Technology
JF  - Journal of Pharmacy Technology
JA  - J PHARM TECHNOL
VL  - 23
IS  - 1
CY  - Thousand Oaks, California
PB  - Sage Publications Inc.
AB  - BACKGROUND: Although personal digital assistant (PDA)-based documentation systems are available for documentation of clinical pharmacy services, none is specific to documentation of drug-related problems (DRPs) in the ambulatory care setting.OBJECTIVE: To describe types of medication interventions performed by pharmacists in an urban ambulatory care clinic within a teaching hospital, determine predictors of preselected DRPs, and describe physician acceptance rates.METHODS: Following development of a PDA-based documentation system, this 6 month prospective study documented interventions performed by a clinical pharmacy team. Descriptive statistics were employed to describe the type and frequency of interventions and physician acceptance rates. Multivariate logistic regression analysis was used to determine significant predictors for preselected DRPs.RESULTS: Over a 6 month period, 965 interventions were documented. The patients' mean +/- SD age was 61.8 +/- 15.51 years, 72.3% of patients were female, and the mean number of medications was 7.1 +/- 3.95 per intervention. The most common interventions were laboratory monitoring (56.2%), patient education (14.5%), and changes in drug therapy (12.4%). The use of antihypertensive agents was a predictor for the DRPs 'dose too high' and 'dose too low' (p = 0.001 and p = 0.003, respectively). Of the applicable interventions, 89.8% (246/274) were accepted by the physician.CONCLUSIONS: Pharmacists in this urban ambulatory care clinic offered a variety of recommendations that were well received by physicians.
SN  - 8755-1225
AD  - Assistant Professor, Chicago College of Pharmacy, Midwestern University, Downers Grove, IL
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105328278
T1  - Perceptions of nurses in nursing homes on the usage of benzodiazepines.
AU  - Anthierens S
AU  - Grypdonck M
AU  - De Pauw L
AU  - Christiaens T
Y1  - 2009/11/15/
N1  - Accession Number: 105328278. Language: English. Entry Date: 20091211. Revision Date: 20150819. Publication Type: Journal Article; research. Journal Subset: Core Nursing; Europe; Nursing; Peer Reviewed; UK & Ireland. Special Interest: Gerontologic Care. NLM UID: 9207302. 
KW  - Antianxiety Agents, Benzodiazepine -- Administration and Dosage -- In Old Age
KW  - Decision Making, Clinical
KW  - Nurse Attitudes
KW  - Nursing Home Personnel
KW  - Nursing Role
KW  - Aged
KW  - Data Analysis Software
KW  - Descriptive Research
KW  - Female
KW  - Focus Groups
KW  - Gerontologic Nursing
KW  - Male
KW  - Nurse-Physician Relations
KW  - Nursing Homes
KW  - Nursing Knowledge
KW  - Organizational Culture
KW  - Purposive Sample
KW  - Qualitative Studies
KW  - Registered Nurses
KW  - Semi-Structured Interview
KW  - Thematic Analysis
KW  - Human
SP  - 3098
EP  - 3106 9p
JO  - Journal of Clinical Nursing
JF  - Journal of Clinical Nursing
JA  - J CLIN NURS
VL  - 18
IS  - 22
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - AIM: This paper reports the findings of a qualitative study on how nurses perceive their own role in the use of benzodiazepines in nursing homes and to identify the factors that have an impact on the nurses' role in the use of benzodiazepines. BACKGROUND: The use of benzodiazepines in nursing homes is of particular concern, as nursing-home residents receive considerably more benzodiazepines than non-institutionalised older persons. Evidence of their long-term effectiveness is lacking. Nurses are important partners in the decision-making process of starting and discontinuation of benzodiazepines. DESIGN: Qualitative descriptive. METHOD: Three focus group interviews and 10 additional semi-structured interviews were used with 33 registered nurses. The interviews were thematically analysed. FINDINGS: Nurses' main concern is to work towards the comfort of the patient. Benzodiazepines are an easy option with not too many side effects and administration of benzodiazepines is experienced as a routine action. When prescribed they will almost automatically lead to chronic usage as there is no evaluation of their effect. There are three aspects that have an impact on nurse's perceptions of their role in benzodiazepine usage: their own individual attitude and perceptions, their knowledge and organisational factors. CONCLUSION: Nurses do not see benzodiazepines as a problem drug and once a prescription is initiated it will almost automatically lead to chronic usage. Nurses should work towards a pro-active promotion of addressing sleeping problems and they can play a key role in non-pharmacological interventions. RELEVANCE TO CLINICAL PRACTICE: Nurses can play a key role in suggesting non-pharmacological alternatives. Education to provide more insight into the problems of insomnia and anxiety may positively influence their attitudes and behaviour. All caregivers in nursing homes should be informed about the relevance of this issue.
SN  - 0962-1067
AD  - Department of General Practice and Primary Health Care, Ghent University, De Pintelaan 185, Ghent, Belgium; sibyl.anthierens@ugent.be
U2  - PMID: 19538562.
DO  - 10.1111/j.1365-2702.2008.02758.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106649648
T1  - Personal digital assistant-based drug information sources: potential to improve medication safety.
AU  - Galt KA
AU  - Rule AM
AU  - Houghton B
AU  - Young DO
AU  - Remington G
Y1  - 2005/04//
N1  - Accession Number: 106649648. Language: English. Entry Date: 20050624. Revision Date: 20150820. Publication Type: Journal Article; research; tables/charts. Journal Subset: Computer/Information Science; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Grant Information: Agency for Healthcare Research and Quality, grant number 1-R18HS11808-01. NLM UID: 101132728. 
KW  - Computers, Hand-Held
KW  - Drug Information Services -- Evaluation
KW  - Medication Errors -- Prevention and Control
KW  - Analysis of Variance
KW  - Checklists
KW  - Information Needs
KW  - Interrater Reliability
KW  - Intrarater Reliability
KW  - Kruskal-Wallis Test
KW  - Patient Safety
KW  - Pharmacists
KW  - Physicians
KW  - Questionnaires
KW  - Reference Tools -- Evaluation
KW  - Scales
KW  - Funding Source
KW  - Human
SP  - 229
EP  - 236 8p
JO  - Journal of the Medical Library Association
JF  - Journal of the Medical Library Association
JA  - J MED LIBR ASSOC
VL  - 93
IS  - 2
CY  - Carol Stream, Illinois
PB  - Medical Library Association
AB  - OBJECTIVES: This study compared the potential for personal digital assistant (PDA)-based drug information sources to minimize potential medication errors dependent on accurate and complete drug information at the point of care. METHODS: A quality and safety framework for drug information resources was developed to evaluate 11 PDA-based drug information sources. Three drug information sources met the criteria of the framework: Eprocrates Rx Pro, Lexi-Drugs, and mobileMICROMEDEX. Medication error types related to drug information at the point of care were then determined. Forty-seven questions were developed to test the potential of the sources to prevent these error types. Pharmacists and physician experts from Creighton University created these questions based on the most common types of questions asked by primary care providers. Three physicians evaluated the drug information sources, rating the source for each question: 1=no information available, 2=some information available, or 3 = adequate amount of information available. RESULTS: The mean ratings for the drug information sources were: 2.0 (Eprocrates Rx Pro), 2.5 (Lexi-Drugs), and 2.03 (mobileMICROMEDEX). Lexi-Drugs was significantly better (mobileMICROMEDEX t test; P=0.05; Eprocrates Rx Pro t test; P=0.01). CONCLUSION: Lexi-Drugs was found to be the most specific and complete PDA resource available to optimize medication safety by reducing potential errors associated with drug information. No resource was sufficient to address the patient safety information needs for all cases.
SN  - 1536-5050
AD  - Professor of Pharmacy Practice, Dept of Pharmacy Practice, Creighton University, 2500 California Plaza, Omaha, NE kgalt@creighton.edu
U2  - PMID: 15858626.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104502044
T1  - Pharmaceutical care issues encountered by post-menopausal osteoporotic women prescribed bisphosphonates.
AU  - Lai, P. S. M.
AU  - Chua, S. S.
AU  - Chan, S. P.
Y1  - 2012/10//
N1  - Accession Number: 104502044. Language: English. Entry Date: 20120910. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts; randomized controlled trial. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Women's Health. Grant Information: This project was funded by the Postgraduate Research Fund P0110/2006B and the Endocrine Research fund, University of Malaya.. NLM UID: 8704308. 
KW  - Osteoporosis -- Drug Therapy
KW  - Diphosphonates -- Therapeutic Use
KW  - Postmenopause
KW  - Human
KW  - Female
KW  - Randomized Controlled Trials
KW  - Random Assignment
KW  - Malaysia
KW  - Medication Compliance
KW  - Quality of Life
KW  - Health Knowledge
KW  - Patient Satisfaction
KW  - Interviews
KW  - Descriptive Statistics
KW  - Diphosphonates -- Adverse Effects
KW  - Adverse Drug Event
KW  - Data Analysis Software
KW  - Adult
KW  - Middle Age
KW  - Aged
KW  - Aged, 80 and Over
KW  - Treatment Outcomes
KW  - Gastrointestinal Diseases -- Etiology
KW  - Pain -- Etiology
KW  - Funding Source
SP  - 536
EP  - 543 8p
JO  - Journal of Clinical Pharmacy & Therapeutics
JF  - Journal of Clinical Pharmacy & Therapeutics
JA  - J CLIN PHARM THER
VL  - 37
IS  - 5
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - What is known and Objective: Pharmacists have been involved in providing comprehensive interventions to osteoporosis patients, but pharmaceutical care issues (PCIs) encountered during such interventions have not been well documented. Therefore, the aim of this study was to document PCIs encountered by post-menopausal osteoporotic women prescribed bisphosphonates. Methods: A randomized controlled study was conducted from September 2005-February 2009 in the University Malaya Medical Centre, Malaysia. This main intervention study measured the effects of pharmaceutical care on medication adherence, persistence, quality of life, knowledge and patient satisfaction. However, this manuscript is part of the main intervention study and focuses only on the PCIs encountered. Inclusion criteria: post-menopausal women diagnosed with osteoporosis (T-score≤−2·5/low-trauma fracture) and prescribed weekly alendronate/risedronate. Exclusion criteria: those with metabolic bone disease and could not communicate in English. The PCIs identified were collected via personal interviews or telephone calls, and each participant was followed-up for a period of 2 years. All PCIs were discussed with and confirmed by a physician. Results and Discussion: Of the 198 participants recruited, 64 (32·3%) experienced adverse effects because of bisphosphonates whereas one participant (0·5%) refused to start bisphosphonates because of fear of adverse effects. Most adverse effects [50 (74·6%)] were reported during the first 3 months of therapy with gastrointestinal problems being the main issue [23 (11·6%)]. Of the nine participants (4·5%) who discontinued bisphosphonates, only three agreed to take another medication. From the 97 PCIs identified, 77 issues could be classified as drug-related problems [according to the Pharmaceutical Care Network Europe Classification v6·2]. There were 87 causes, 178 interventions and 77 outcomes. The main problem and cause of the PCIs encountered were adverse drug events (83·1% and 74·7% respectively), whereas the main intervention provided was patient counselling (41·0%). All problems were solved (98·5%) except for one because of the lack of cooperation of a patient. After 2 years, 36 participants (20%) were no longer persistent with therapy, 19 (10·6%) did not have clinic follow-up and 53 (26·8%) did not have a bone mineral density scan. What is new and Conclusion: The main PCIs identified were related to the use of bisphosphonates and its adverse effects. The study showed that the presence of a clinical pharmacist has enabled patients to voice their medication-related issues and to allow appropriate recommendations and actions to be taken to resolve these issues.
SN  - 0269-4727
AD  - Department of Primary Care Medicine, Faculty of Medicine, University of Malaya; Department of Pharmacy, Faculty of Medicine, University of Malaya
AD  - Department of Pharmacy, Faculty of Medicine, University of Malaya
AD  - Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
U2  - PMID: 22380577.
DO  - 10.1111/j.1365-2710.2012.01335.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106538832
T1  - Pharmacist involvement in a multidisciplinary inpatient medication education program.
AU  - Calabrese AT
AU  - Cholka K
AU  - Lenhart SE
AU  - McCarty B
AU  - Zewe G
AU  - Sunseri D
AU  - Roberts M
AU  - Kapoor W
Y1  - 2003/05/15/
N1  - Accession Number: 106538832. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article; algorithm; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Drug Therapy -- Economics
KW  - Patient Education
KW  - Pharmacists
KW  - Academic Medical Centers
KW  - Inpatients
KW  - Multidisciplinary Care Team
KW  - Nurses
KW  - Pennsylvania
KW  - Professional Role
KW  - Program Development
KW  - Program Evaluation
KW  - Program Implementation
SP  - 1012
EP  - 1018 7p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 60
IS  - 10
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
AB  - The development of a multidisciplinary inpatient medication education program is described. A multidisciplinary group designed and implemented a medication education program with defined roles for both nurses and pharmacists. Nurses provided medication education to patients during each medication administration using specially designed assessment and teaching tools. The nursing staff submitted requests for pharmacist consultations for patients with complex medication regimens, who were admitted because of a drug-related problem or who required additional teaching as determined through the medication education assessment form. A complex medication regimen was defined as the administration of oral medication more than five different times per day, the start of at least 5 new medications that would be continued at discharge, or the prescribing of at least 10 medications to be taken daily that would be continued at discharge. Pharmacists provided education for 19% of admitted patients during a six-month period. As a result of pharmacists' interactions with prescribers and nurses, the number of medications was reduced in 12% of these patients, and the number of medication administrations each day was reduced in 19% of patients. In addition, for 33% of patients, pharmacists contacted the prescriber to make recommendations beyond the scope of the medication education program that optimized and simplified the patient's drug regimen. The development of a structured medication education program allowed patients to receive medication education throughout their hospitalization from both nurses and pharmacists. Pharmacists provided education for patients at highest risk for noncompliance or poor outcomes. Full implementation of a medication education program involving staff pharmacists is planned.
SN  - 1079-2082
AD  - Assistant Professor, Pharmacy and Therapeutics, University of Pittsburgh Medical Center Health System, 302 Scaife Hall, 200 Lothrop Street, Pittsburgh, PA 15213; calabresea@msx.upmc.edu
U2  - PMID: 12789872.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104583764
T1  - Pharmacist web-based training program on medication use in chronic kidney disease patients: Impact on knowledge, skills, and satisfaction.
AU  - Legris, Marie-éve
AU  - Séguin, Noémie Charbonneau
AU  - Desforges, Katherine
AU  - Sauvé, Patricia
AU  - Lord, Anne
AU  - Bell, Robert
AU  - Berbiche, Djamal
AU  - Desrochers, Jean-François
AU  - Lemieux, Jean-Philippe
AU  - Morin-Bélanger, Claudia
AU  - Ste-Marie Paradis, François
AU  - Lalonde, Lyne
Y1  - 2011///Summer2011
N1  - Accession Number: 104583764. Language: English. Entry Date: 20111208. Revision Date: 20150711. Publication Type: Journal Article; pictorial; research; tables/charts; randomized controlled trial. Journal Subset: Canada; Editorial Board Reviewed; Expert Peer Reviewed; Health Promotion/Education; Peer Reviewed. Grant Information: This study was funded by a research grant from the Cercle du Doyen of the Faculty of Pharmacy of the Universite de Montreal and an unrestricted grant from Amgen Canada Inc.. NLM UID: 8805847. 
KW  - Kidney Failure, Chronic -- Drug Therapy
KW  - Pharmacists -- Education
KW  - World Wide Web
KW  - Education, Medical, Continuing -- Evaluation
KW  - Program Evaluation
KW  - Human
KW  - Outcomes of Education
KW  - Questionnaires
KW  - Vignettes
KW  - Semi-Structured Interview
KW  - Randomized Controlled Trials
KW  - Adverse Drug Event -- Education
KW  - Pretest-Posttest Design
KW  - Professional Knowledge -- Evaluation
KW  - Summated Rating Scaling
KW  - Audiorecording
KW  - Descriptive Statistics
KW  - Confidence Intervals
KW  - Linear Regression
KW  - Secondary Analysis
KW  - Attitude of Health Personnel -- Evaluation
KW  - Funding Source
SP  - 140
EP  - 150 11p
JO  - Journal of Continuing Education in the Health Professions
JF  - Journal of Continuing Education in the Health Professions
JA  - J CONTIN EDUC HEALTH PROF
VL  - 31
IS  - 3
CY  - Hoboken, New Jersey
PB  - John Wiley & Sons, Inc.
AB  - Introduction: Chronic kidney disease (CKD) patients are multimorbid elderly at high risk of drug-related problems. A Web-based training program was developed based on a list of significant drug-related problems in CKD patients requiring a pharmaceutical intervention. The objectives were to evaluate the impact of the program on community pharmacists' knowledge and skills and their satisfaction with the training. Methods: Pharmacists were randomized to the training program or the control group. Training comprised a 60-minute Web-based interactive session supported by a clinical guide. Pharmacists completed a questionnaire on knowledge (10 multiple-choice questions) and skills (2 clinical vignettes) at baseline and a second time within 1 month. Trained pharmacists completed a written satisfaction questionnaire. Semidirected telephone interviews were conducted with 8 trained pharmacists. Changes in knowledge and skills scores were compared between the groups. Results: Seventy pharmacists (training: 52; control: 18) were recruited; the majority were women with <15 years' experience. Compared with the control group, an adjusted incremental increase in the knowledge score (22%; 95% confidence interval [CI]: 16%-27%) and skills score (24%; 95% CI: 16%-33%) was observed in the training group. Most pharmacists (87%-100%) rated each aspect of the program 'excellent'' or 'very good.' Additional training and adding a discussion forum were suggested to complement the program. Discussion: Pharmacists like the Web-based continuing education program. Over a short time span, the program improved their knowledge and skills. Its impact on their clinical practices and quality of medication use in CKD patients remains to be assessed.
SN  - 0894-1912
AD  - Université de Montréal; Hôpital Maisonneuve-Rosemont
AD  - Faculty of Pharmacy, Université de Montréal; Hôpital Maisonneuve-Rosemont
AD  - Faculty of Pharmacy, Université de Montréal; Centre de santé et de services sociaux de Laval
AD  - Centre de santé et de services sociaux de Laval
AD  - Hôpital Maisonneuve-Rosemont
AD  - Équipe de recherche en soins de première ligne, Centre de santé et de services sociaux de Laval
AD  - Faculty of Pharmacy, Université de Montréal; Équipe de recherche en soins de première ligne, Centre de santé et de services sociaux de Laval; Sanofi Aventis Endowment Research Chair in Ambulatory Pharmaceutical Care, Faculty of Pharmacy, Université de Montréal
U2  - PMID: 21953653.
DO  - 10.1002/chp.20119
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104337836
T1  - Pharmacists' and Pharmacy Students' Ability to Identify Drug-related Problems Using TIMER (Tool to Improve Medications in the Elderly via Review)
AU  - Lee, Sarah Snyder
AU  - Schwemm, Ann K.
AU  - Reist, Jeffrey
AU  - Cantrell, Matthew
AU  - Andreski, Michael
AU  - Doucette, William R.
AU  - Chrischilles, Elizabeth A.
AU  - Farris, Karen B.
Y1  - 2009/08//
N1  - Accession Number: 104337836. Language: English. Entry Date: 20130301. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; USA. 
SP  - 1
EP  - 10 10p
JO  - American Journal of Pharmaceutical Education
JF  - American Journal of Pharmaceutical Education
JA  - AM J PHARMACEUTICAL EDUC
VL  - 73
IS  - 3
CY  - Alexandria, Virginia
PB  - American Association of Colleges of Pharmacy
SN  - 0002-9459
AD  - Kansas University Medical Center.
AD  - University of Michigan Health System.
AD  - University of Iowa College of Pharmacy.; University of Iowa Hospitals and Clinics.
AD  - University of Iowa College of Pharmacy.; Veterans Affairs Medical Center, Iowa City.
AD  - University of Iowa College of Pharmacy.
AD  - University of Iowa College of Public Health.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105819499
T1  - Pharmacists on a primary care team at a Veterans Affairs medical center.
AU  - Chandler C
AU  - Barriuso P
AU  - Rozenberg-Ben-Dror K
AU  - Schmitt B
Y1  - 1997/06//1997 Jun 1
N1  - Accession Number: 105819499. Language: English. Entry Date: 20080307. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Family Practice
KW  - Multidisciplinary Care Team -- Administration
KW  - Pharmacists
KW  - Female
KW  - Illinois
KW  - Interprofessional Relations
KW  - Male
KW  - Pharmacy Service
KW  - Quality of Health Care
KW  - Role
KW  - United States Department of Veterans Affairs
KW  - United States
SP  - 1280
EP  - 1287 8p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 54
IS  - 11
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
AB  - The role of pharmacists on a primary care team in the VA Chicago Health Care System--Lakeside Division is described. In 1990 the Veterans Affairs Lakeside Medical Center (now called the VA Chicago Health Care System--Lakeside Division) implemented the 'Firm' system to improve the quality of patient care. This system split the original primary care clinics into three identical but smaller groups, or Firms. Each Firm provides three types of care: longitudinal care (ongoing care with a primary care physician), interim care (frequent care and close patient monitoring between primary physician visits), and un-scheduled care (acute care for complaints that may require immediate attention). Each Firm has a care team composed of physicians, a pharmacist, nurses, and other health care personnel. The pharmacist assists with interim care and, in conjunction with Firm physicians, is involved in follow-up and monitoring of drug therapy and identification of new problems. Originally it was expected that pharmacists would care for 30-40% of interim care patients, but Firm pharmacists have assisted in providing care to over 50% of these patients (plus 4% of un-scheduled care patients). The pharmacists have received high ratings from the internal medicine resident staff. Pharmacists on multidisciplinary care teams provided primary care to more than half of outpatient veterans in need of health care between regularly scheduled appointments.
SN  - 1079-2082
U2  - PMID: 9179348.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109594162
T1  - Pharmacists' role in handling problems with prescriptions for antithrombotic medication in Belgian community pharmacies.
AU  - Desmaele, S
AU  - De Wulf, I
AU  - Dupont, A G
AU  - Steurbaut, S
Y1  - 2015/08//
N1  - Accession Number: 109594162. Language: English. Entry Date: 20150923. Revision Date: 20160412. Publication Type: journal article. Journal Subset: Biomedical; Continental Europe; Europe. NLM UID: 101554912. 
SP  - 656
EP  - 668 13p
JO  - International Journal of Clinical Pharmacy
JF  - International Journal of Clinical Pharmacy
JA  - INT J CLIN PHARM
VL  - 37
IS  - 4
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
AB  - Background: Community pharmacists have an important task in the follow-up of patients treated with antithrombotics. When delivering these medicines, pharmacists can encounter drug-related problems (DRPs) with substantial clinical and economic impact.Objective: To investigate the amount and type of antithrombotic related DRPs as well as how community pharmacists handled these DRPs.Setting: Belgian community pharmacies.Methods: MSc pharmacy students of six Belgian universities collected data about all DRPs encountered by a pharmacist during ten half days of their pharmacy internship. Data were registered about DRPs detected at delivery and in an a posteriori setting, when consulting the medical history of the patient. Classification of the DRP, cause of the DRP, intervention and result of the intervention were registered.Main Outcome Measure: Amount and type of antotrombitocs related DRPs occurring in community pharmacies, as well as how community pharmacists handled these DRPs.Results: 3.1 % of the 15,952 registered DRPs concerned antithrombotics. 79.3 % of these DRPs were detected at delivery and 20.7 % were detected a posteriori. Most antithrombotic-related DRPs concerned problems with the choice of the drug (mainly because of drug-drug interactions) or concerned logistic problems. Almost 80 % of the antithrombotic-related DRPs were followed by an intervention of the pharmacist, mainly at the patient's level, resulting in 90.1 % of these DRPs partially or totally solved.Conclusion: Different DRPs with antithrombotic medication occurred in Belgian community pharmacies. About 20 % was detected in an a posteriori setting, showing the benefit of medication review. Many of the encountered DRPs were of technical nature (60.7 %). These DRPs were time-consuming for the pharmacist to resolve and should be prevented. Most of the DRPs could be solved, demonstrating the added value of the community pharmacist as first line healthcare provider.
SN  - 2210-7703
U2  - PMID: 25822042.
DO  - 10.1007/s11096-015-0106-3
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109656363
T1  - Pharmacist's Role in Improving Medication Safety for Patients in an Allogeneic Hematopoietic Cell Transplant Ambulatory Clinic.
AU  - Ho, Lina
AU  - Akada, Keith
AU  - Messner, Hans
AU  - Kuruvilla, John
AU  - Wright, Janice
AU  - Seki, Jack T
Y1  - 2013/03//2013 Mar
N1  - Accession Number: 109656363. Language: English. Entry Date: 20150923. Revision Date: 20150923. Publication Type: Journal Article. Journal Subset: Biomedical; Canada. NLM UID: 0215645. 
SP  - 110
EP  - 117 8p
JO  - Canadian Journal of Hospital Pharmacy
JF  - Canadian Journal of Hospital Pharmacy
JA  - CAN J HOSP PHARM
VL  - 66
IS  - 2
CY  - Milton, Ontario
PB  - Multimed Inc.
AB  - BACKGROUND: Patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT), supported by complex drug regimens, are vulnerable to drug therapy problems (DTPs) at interfaces of care after discharge from hospital and may benefit from timely pharmacy interventions and education. OBJECTIVE: To determine the effect on medication safety of, as well as potential barriers to, incorporating a pharmacist in the multidisciplinary team of an allo-HCT clinic. METHODS: Two pharmacists rotated to attend the allo-HCT clinic of a tertiary care, university-affiliated cancer centre between January and June 2010 (coverage for 1 of 3 clinic days per week). For every patient who was seen by a pharmacist, all discharge medications were reconciled from the inpatient ward to the clinic. The pharmacists' primary task was to perform medication reconciliation and to identify and resolve DTPs. The pharmacists also provided medication education to patients and pharmacy consultations to clinic staff. Working with the outpatient pharmacy, the pharmacists helped to clarify prescriptions and drug coverage issues. Medication discrepancies identified and interventions performed by the pharmacists were recorded and were later graded for clinical significance by a panel of clinicians. Patient and staff satisfaction surveys were conducted at random during the study period. Barriers to the flow of patient care and other operational issues were documented. RESULTS: The 2 pharmacists saw a total of 35 patients over 100 visits. They identified a total of 50 medication discrepancies involving 17 (49%) of the patients and 70 DTPs involving 23 (66%) of the patients. Thirty-one of the 70 DTPs resulted directly from a medication discrepancy. Twenty (95%) of the 21 unintentional medication discrepancies and 7 (70%) of the 10 undocumented intentional medication discrepancies were graded as clinically significant or moderately significant. Satisfaction surveys completed by patients and clinic staff yielded positive responses supporting pharmacists' participation. CONCLUSIONS: Pharmacists working as part of the multidisciplinary team identified and resolved medication discrepancies, thereby improving medication safety at the allo-HCT clinic.
SN  - 0008-4123
AD  - , BScPhm, ACPR, is with the Department of Pharmacy, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario.
U2  - PMID: 23616675.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107793560
T1  - Pharmacists' training, perceived roles, and actions associated with dispensing controlled substance prescriptions.
AU  - Fleming, Marc L
AU  - Barner, Jamie C
AU  - Brown, Carolyn M
AU  - Shepherd, Marv D
AU  - Strassels, Scott A
AU  - Novak, Suzanne
Y1  - 2014/05//May/Jun2014
N1  - Accession Number: 107793560. Language: English. Entry Date: 20150417. Revision Date: 20150712. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 101176252. 
KW  - Attitude of Health Personnel
KW  - Drugs, Prescription -- Administration and Dosage
KW  - Drug Monitoring
KW  - Prescriptions, Drug
KW  - Education, Pharmacy
KW  - Pharmacists -- Psychosocial Factors
KW  - Analgesics, Opioid -- Administration and Dosage
KW  - Analgesics, Opioid -- Adverse Effects
KW  - Pharmacy, Retail
KW  - Drugs, Prescription -- Adverse Effects
KW  - Cross Sectional Studies
KW  - Data Collection
KW  - Female
KW  - Human
KW  - Male
KW  - Middle Age
KW  - Substance Use Disorders -- Prevention and Control
KW  - Texas
SP  - 241
EP  - 250 10p
JO  - Journal of the American Pharmacists Association: JAPhA
JF  - Journal of the American Pharmacists Association: JAPhA
JA  - J AM PHARM ASSOC
VL  - 54
IS  - 3
CY  - Washington, District of Columbia
PB  - American Pharmacists Association
SN  - 1544-3191
U2  - PMID: 24816350.
DO  - 10.1331/JAPhA.2014.13168
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106198401
T1  - Pharmacokinetics, pharmacodynamics, and pharmacogenomics of opioids.
AU  - Paice JA
Y1  - 2007/09/02/Sep2007 Supplement 1
N1  - Accession Number: 106198401. Language: English. Entry Date: 20071130. Revision Date: 20150820. Publication Type: Journal Article; tables/charts. Supplement Title: Sep2007 Supplement 1. Journal Subset: Blind Peer Reviewed; Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Pain and Pain Management. NLM UID: 100890606. 
KW  - Analgesics, Opioid -- Pharmacodynamics
KW  - Analgesics, Opioid -- Pharmacokinetics
SP  - S2
EP  - 5 1p
JO  - Pain Management Nursing
JF  - Pain Management Nursing
JA  - PAIN MANAGE NURS
VL  - 8
IS  - 3
CY  - Philadelphia, Pennsylvania
PB  - W B Saunders
AB  - Of late, the realization that unrelieved pain continues to be a prevalent problem despite the availability of effective analgesic agents has encouraged a movement toward establishing a balance between the prevention of drug misuse, abuse, and diversion, and the provision of adequate pain control. In this and other publications, opioids have been acknowledged as essential medications that are necessary for the relief of chronic, pain-inducing conditions. Yet, it is still important to integrate risk management into programs of care and for clinicians to develop skills to minimize risks of misuse, abuse, and diversion of medications. Despite opioids' historical longevity and established place in the armamentarium of analgesics for control of both acute and chronic pain, recent advancements in the field war-rant reconsideration of the available data on opioids. For example, developments in pharmacogenomics research have demonstrated that the intrinsic analgesic mechanisms, pharmacokinetics, and metabolism of opioids are dictated by an individual's genetics. This has important clinical ramifications. Because each patient has a unique genetic background, analgesic regimens need to be individualized for each patient to maximize analgesic opioid effects and minimize side effects. Moreover, opioid rotation should be considered when analgesia to a particular pharmacotherapy is inadequate or induces significant adverse effects. © 2007 by the American Society for Pain Management Nursing
SN  - 1524-9042
AD  - Cancer Pain Program, Division of Hematology-Oncology, Feinberg School of Medicine, Northwestern University, 676 North St. Clair Street, Suite 850, Chicago, IL 60611; j-paice@northwestern.edu
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106198401&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107956194
T1  - Pharmacologic Abuse: A National Epidemic...Reprinted with permission from the Illinois Nurses Association
AU  - Patrick, Dee-Dee
Y1  - 2013/07//
N1  - Accession Number: 107956194. Language: English. Entry Date: 20130711. Revision Date: 20151015. Publication Type: Journal Article. Note: Reprint from Illinois Nurses Association ft omitted due to copyright. Journal Subset: Nursing; Peer Reviewed; USA. NLM UID: 0061156. 
KW  - Substance Abuse
KW  - Substance Abuse -- Education
KW  - Substance Abuse -- Epidemiology
KW  - Substance Abuse -- Etiology
KW  - Substance Abuse -- Prevention and Control
SP  - 14
EP  - 15 2p
JO  - Nursing News
JF  - Nursing News
JA  - NURS NEWS (NEW HAMPSHIRE)
VL  - 37
IS  - 3
CY  - Concord, New Hampshire
PB  - New Hampshire Nurses' Association
SN  - 0029-6538
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107956194&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105696604
T1  - Pharmacological treatment of behavioral and psychological symptoms of dementia (BPSD) in nursing homes: development of practice recommendations in a Swiss canton.
AU  - Locca J
AU  - Büla CJ
AU  - Zumbach S
AU  - Bugnon O
Y1  - 2008/07//
N1  - Accession Number: 105696604. Language: English. Entry Date: 20081121. Revision Date: 20150711. Publication Type: Journal Article; algorithm; research; systematic review; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Evidence-Based Practice; Gerontologic Care. NLM UID: 100893243. 
KW  - Agitation -- Drug Therapy -- In Old Age
KW  - Dementia -- Complications -- In Old Age
KW  - Depression -- Drug Therapy -- In Old Age
KW  - Gerontologic Care
KW  - Insomnia -- Drug Therapy -- In Old Age
KW  - Long Term Care
KW  - Aged
KW  - Aged, 80 and Over
KW  - Angiotensin-Converting Enzyme Inhibitors -- Therapeutic Use
KW  - Anticonvulsants -- Therapeutic Use
KW  - Cochrane Library
KW  - Descriptive Statistics
KW  - Female
KW  - Inpatients
KW  - Male
KW  - Medline
KW  - Melatonin -- Therapeutic Use
KW  - Meta Analysis
KW  - Nursing Home Patients
KW  - Nursing Homes
KW  - Psychotropic Drugs -- Therapeutic Use
KW  - PubMed
KW  - Switzerland
KW  - Human
SP  - 439
EP  - 448 10p
JO  - Journal of the American Medical Directors Association
JF  - Journal of the American Medical Directors Association
JA  - J AM MED DIR ASSOC
VL  - 9
IS  - 6
CY  - New York, New York
PB  - Elsevier Science
AB  - OBJECTIVES: In 2002, the canton of Fribourg, Switzerland, implemented a coordinated pharmaceutical care service in nursing homes to promote rational drug use. In the context of this service, a project was conducted to develop recommendations for the pharmacological management of behavioral and psychological symptoms of dementia (BPSD) in nursing home residents. DESIGN AND METHODS: Selected evidence-based guidelines and meta-analysis sources related to the management of depression, insomnia, and agitation in dementia patients were systematically searched and evaluated. Evidence and controversies regarding the pharmacological treatment of the most common BPSD symptoms were reviewed, and treatment algorithms were developed. RESULTS: Ten evidence-based guidelines and meta-analyses for BPSD management were identified, with none specifically addressing issues related to nursing home residents. Based on this literature, recommendations were developed for the practice of pharmacological management of depression, sleep disturbances, and agitation in nursing home residents. For depression, SSRIs are considered the first choice if an antidepressant is required. No clear evidence has been found for sleep disturbances; the underlying conditions need to be investigated closely before the introduction of any drug therapy. Many drugs have been investigated for the treatment of agitation, and if necessary, antipsychotics could be used, although they have significant side effects. Several areas of uncertainty were identified, such as the current controversy about typical and atypical antipsychotic use or the appropriateness of cholinesterase inhibitors for controlling agitation. Treatment algorithms were presented to general practitioners, pharmacists, and medical directors of nursing homes in the canton of Fribourg, and will now be implemented progressively, using educational sessions, pharmaceutical counseling, and monitoring. CONCLUSION: Based on existing evidence-based studies, recommendations were developed for the practice of pharmacological management of depression, sleep disturbances, and agitation in nursing home residents. It should be further studied whether these algorithms implemented through pharmaceutical care services will improve psychotropic drug prescriptions and prevent drug-related problems in nursing home residents.
SN  - 1525-8610
AD  - Universities of Lausanne and Geneva, Community Pharmacy Practice Research Unit, Pharmacie de la PMU, Lausanne, Switzerland.
U2  - PMID: 18585647.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104317900
T1  - Pharmacology Continuing Education Posttest.
AU  - Woo, Teri Moser
AU  - Hanley, James R.
Y1  - 2013/03//
N1  - Accession Number: 104317900. Language: English. Entry Date: 20130225. Revision Date: 20150711. Publication Type: Journal Article; CEU; exam questions. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Special Interest: Advanced Nursing Practice; Pediatric Care. NLM UID: 8709735. 
KW  - Substance Abuse -- Prevention and Control -- In Adolescence
KW  - Substance Abuse -- Diagnosis -- In Adolescence
KW  - Education, Continuing (Credit)
KW  - Adolescence
SP  - 145
EP  - 147 3p
JO  - Journal of Pediatric Healthcare
JF  - Journal of Pediatric Healthcare
JA  - J PEDIATR HEALTH CARE
VL  - 27
IS  - 2
CY  - New York, New York
PB  - Elsevier Science
SN  - 0891-5245
DO  - 10.1016/j.pedhc.2012.12.003
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104462230
T1  - Pharmacology update. Pharmacologic approaches to smoking cessation.
AU  - Bailey, Abby M
AU  - Macaulay, Tracy
Y1  - 2012/06//
N1  - Accession Number: 104462230. Language: English. Entry Date: 20120824. Revision Date: 20150711. Publication Type: Journal Article; pictorial; tables/charts. Journal Subset: Allied Health; Biomedical; Peer Reviewed; USA. Special Interest: Perioperative Care; Physical Therapy. NLM UID: 7806107. 
KW  - Orthopedic Surgery
KW  - Smoking Cessation
KW  - Smoking -- Complications
KW  - Smoking -- Drug Therapy
KW  - Administration, Intranasal
KW  - Adolescence
KW  - Bupropion -- Therapeutic Use
KW  - Chewing Gum
KW  - Child
KW  - Depression
KW  - Female
KW  - Male
KW  - Nebulizers and Vaporizers
KW  - Nicotine Replacement Therapy
KW  - Nicotine -- Administration and Dosage
KW  - Receptors, Cell Surface -- Antagonists and Inhibitors
KW  - Schizophrenia
KW  - Sex Factors
KW  - Substance Abuse
KW  - Substance Dependence
KW  - Transdermal Patches, Drugs
KW  - Treatment Outcomes
SP  - 505
EP  - 511 7p
JO  - Orthopedics
JF  - Orthopedics
JA  - ORTHOPEDICS
VL  - 35
IS  - 6
CY  - Thorofare, New Jersey
PB  - SLACK Incorporated
AB  - Cigarette smokers experience greater rates of morbidity and mortality. Despite the known health risks, use of tobacco products remains high throughout the United States (approximately 19.3% of adults). Tobacco use is associated with higher rates of cardiovascular illness, cardiovascular risk factors (ie, hypertension and atherosclerosis), chronic obstructive pulmonary disease, emphysema, and various types of cancer. Pharmacologic smoking cessation therapies have been used to facilitate abstinence from smoking. This article provides clinicians with instructions for the use of pharmacologic agents for smoking cessation, including considerations for special populations.
SN  - 0147-7447
U2  - PMID: 22691640.
DO  - 10.3928/01477447-20120525-07
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108126514
T1  - Pharmacotherapy for adolescent alcohol use disorder.
AU  - Clark DB
Y1  - 2012/07//
N1  - Accession Number: 108126514. Language: English. Entry Date: 20121102. Revision Date: 20150712. Publication Type: Journal Article. Journal Subset: Australia & New Zealand; Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed. NLM UID: 9431220. 
KW  - Alcohol-Related Disorders -- Drug Therapy
KW  - Substance Withdrawal Syndrome -- Drug Therapy
KW  - Adolescence
KW  - Antidepressive Agents -- Therapeutic Use
KW  - Attention Deficit Hyperactivity Disorder -- Drug Therapy
KW  - Antianxiety Agents, Benzodiazepine -- Therapeutic Use
KW  - Central Nervous System Stimulants -- Therapeutic Use
KW  - Comorbidity
KW  - DSM
KW  - Disulfiram -- Therapeutic Use
KW  - Naltrexone -- Therapeutic Use
KW  - Substance Use Disorders -- Drug Therapy
KW  - Alkanes
KW  - Alkanes -- Therapeutic Use
SP  - 559
EP  - 569 11p
JO  - CNS Drugs
JF  - CNS Drugs
JA  - CNS DRUGS
VL  - 26
IS  - 7
PB  - Springer Science & Business Media B.V.
AB  - Alcohol use disorder (AUD) occurs in few young adolescents, but is as common as in adults by the late teens. To address problems with the current American Psychiatric Association DSM-IV criteria, the anticipated DSM-V will eliminate the distinction between substance abuse and dependence in favour of a single category. For adolescents, pharmacotherapy for AUD may target alcohol withdrawal symptoms, alcohol consumption reinforcement properties, craving or co-morbid mental disorders. While uncommon among adolescents, severe alcohol withdrawal may require the closely monitored application of benzodiazepines. Disulfiram alters alcohol metabolism and has been shown to increase abstinence in adolescents with AUD, but sufficient motivation to maintain abstinence is needed for this approach to be appropriate. Medications to reduce alcohol craving, including naltrexone and acamprosate, may also assist some adolescents in maintaining abstinence. Adolescents with AUD typically also have co-morbid mental disorders and problems with other substances. Co-morbid mental disorders, such as major depressive disorder and attention-deficit hyperactivity disorder, may be addressed by pharmacotherapy. The potential for interactions between prescribed medications and alcohol or illicit substances necessitates patient education and monitoring. While there is a paucity of empirical information on the applicability of these pharmacotherapy approaches in adolescents, cautious application of these medications in selected cases in the context of systematic psychosocial interventions is warranted to promote abstinence and address associated problems.
SN  - 1172-7047
AD  - Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
U2  - PMID: 22676261.
DO  - 10.2165/11634330-000000000-00000
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108126514&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106406571
T1  - Pharmacotherapy strategies for alcoholism treatment.
AU  - McCaul ME
Y1  - 2004/04//2004 Apr
N1  - Accession Number: 106406571. Language: English. Entry Date: 20060310. Revision Date: 20150818. Publication Type: Journal Article; CEU; exam questions; review; tables/charts. Journal Subset: Nursing; USA. 
KW  - Alcoholism -- Drug Therapy
KW  - Alcohol Deterrents -- Therapeutic Use
KW  - Diagnosis, Dual (Psychiatry)
KW  - Education, Continuing (Credit)
KW  - Naltrexone -- Therapeutic Use
SP  - 54
EP  - 69 9p
JO  - Johns Hopkins Advanced Studies in Nursing
JF  - Johns Hopkins Advanced Studies in Nursing
JA  - JOHNS HOPKINS ADV STUD NURS
VL  - 2
IS  - 2
CY  - Somerville, New Jersey
PB  - Galen Publishing, LLC
AB  - This paper reviews various pharmacologic strategies for the treatment of alcohol dependence based on what has been learned of the neurobiology of this condition. Aspects of treatment are twofold, focusing initially on acute withdrawal management followed by abstinence maintenance treatments. Specific strategies discussed include deterrence, reward, reduction, and treatment of comorbid psychiatric disorders. The benefits and side effects of disulfiram, naltrexone, acamprosate, and selective serotonin reuptake inhibitors (SSRIs) are considered, as these are the most commonly prescribed agents. Focal points to guide future therapeutic directions include increased attention to behavioral strategies underpinning medication use, increased attention to combinations of medications versus monotherapy, and increased attention to individual differences among patients.
SN  - 1558-0172
AD  - Johns Hopkins University School of Medicine, 911 N Broadway, Baltimore, MD 21205. E-mail: betsymc@jhmi.edu
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106406571&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106126087
T1  - Pharmacotherapy: integrating new tools into practice: an introduction from AP's editor to the NAADAC Lifelong Learning Series.
Y1  - 2007/01//2007 Jan-Feb
N1  - Accession Number: 106126087. Language: English. Entry Date: 20070727. Revision Date: 20150711. Publication Type: Journal Article; brief item; CEU; exam questions; pictorial. Journal Subset: Biomedical; USA. Special Interest: Psychiatry/Psychology. NLM UID: 101176508. 
KW  - Alcoholism -- Therapy
KW  - Combined Modality Therapy
KW  - Drug Therapy
KW  - Education, Continuing (Credit)
KW  - Support, Psychosocial -- Methods
SP  - 32
EP  - 45 3p
JO  - Addiction Professional
JF  - Addiction Professional
JA  - ADDICT PROF
VL  - 5
IS  - 1
CY  - New York, New York
PB  - Vendome Group LLC
AB  - NAADAC, The Association for Addiction Professionals and Fusion Medical Education launch a yearlong series of articles designed to present the latest information on use of medications in alcohol dependence treatment. The first article in this series explores how medication can interact with the process of change in alcohol-dependent patients.
SN  - 1542-8435
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106126087&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107225760
T1  - Pharmacy access to syringes among injecting drug users: follow-up findings from Hartford, Connecticut.
AU  - Singer M
AU  - Baer HA
AU  - Scott G
AU  - Horowitz S
AU  - Weinstein B
Y1  - 1998/06/02/1998 Jun Suppl 1
N1  - Accession Number: 107225760. Language: English. Entry Date: 19991101. Revision Date: 20150711. Publication Type: Journal Article; research; statistics; tables/charts. Supplement Title: 1998 Jun Suppl 1. Journal Subset: Biomedical; Peer Reviewed; Public Health; USA. Grant Information: This study was supported by National Institute on Drug Abuse Grant No. R01 DA09224 with assistance from the Connecticut Department of Public Health AIDS Program. NLM UID: 9716844. 
KW  - Needle Sharing -- Prevention and Control
KW  - Syringes -- Legislation and Jurisprudence -- Connecticut
KW  - Substance Abuse, Intravenous
KW  - HIV Infections -- Prevention and Control
KW  - Evaluation Research
KW  - Interviews
KW  - Surveys
KW  - Telephone
KW  - Descriptive Statistics
KW  - Pharmacy Service
KW  - Substance Abusers
KW  - Racism
KW  - Connecticut
KW  - Male
KW  - Female
KW  - Funding Source
KW  - Human
SP  - 81
EP  - 89 9p
JO  - Public Health Reports
JF  - Public Health Reports
JA  - PUBLIC HEALTH REP
VL  - 113
CY  - Washington, District of Columbia
PB  - Association of Schools & Programs of Public Health
AB  - Objective. To break the link between drug use and the human immunodeficiency virus (HIV), in 1992 the state of Connecticut rescinded a 14-year ban on pharmacy sales of syringes without a physician's prescription. In 1993, the Centers for Disease Control and Prevention (CDC) evaluated the impact of the new legislation on access to syringes among injecting drug users (IDUs) and found an initial pattern of expanded access. However, it also found that some pharmacies, after negative experiences with IDU customers, reverted to requiring a prescription. This chapter reports findings from a four-year follow-up study of current IDU access to over-the-counter (OTC) pharmacy syringes in Hartford, Connecticut. Methods. Through structured interviews, brief telephone interviews, and mailed surveys, data on nonprescription syringe sale practices were collected on 27 pharmacies, including 18 of the 21 pharmacies in Hartford and nine from pharmacies in contiguous towns, during June and July 1997. Interview data on pharmacy syringe purchase from two samples of IDUs, a group of out-of-treatment injectors recruited through street outreach, and a sample of users of the Hartford Needle Exchange Program, also are reported. Results. The study found that, while market trends as well as negative experiences have further limited pharmacy availability of nonprescription syringes, pharmacies remain an important source of sterile syringes for IDUs. However, the distribution of access is not even; in some areas of the city it is much easier to purchase nonprescription syringes than in others. All of the seven pharmacies located on the north end of Hartford reported that they had a policy of selling OTC syringes, whereas only six (54.5%) of the 11 pharmacies located on the south end have such a policy. Overt racial discrimination was not found to be a barrier to OTC access to syringes. Conclusions. To further decrease acquired immunodeficiency syndrome (AIDS) risk among IDUs, there is a need for public education to counter empirically unsupported stereotypes about IDUs that diminish their access to health care and AIDS prevention resources and services. In states or cities where pharmacy sale of nonprescription syringes is illegal, policy makers should examine the benefits of removing existing barriers to sterile syringe acquisition. In cases in which pharmacy sale of nonprescription syringes is legal, local health departments should implement educational programs to inform pharmacy staff and management about the critically important role low-cost (or cost-free), sterile syringe access can play in HIV prevention.
SN  - 0033-3549
AD  - Hispanic Health Council, 175 Main St, Hartford, CT 06106; email anthro8566@aol.com
U2  - PMID: 9722813.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107225760&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104355730
T1  - Pharmacy residents and students as an adjunct to current smoking cessation education.
AU  - Franks, Andrea S.
AU  - Givens, Carrie B.
AU  - Barger-Stevens, Amy
Y1  - 2012/04//Apr-Jun2012
N1  - Accession Number: 104355730. Language: English. Entry Date: 20130109. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. Special Interest: Public Health. 
KW  - Smoking Cessation -- Education
KW  - Students, Pharmacy -- Utilization
KW  - Pharmacists -- Utilization
KW  - Academic Medical Centers
KW  - Human
KW  - Odds Ratio
KW  - Confidence Intervals
KW  - United States
KW  - Smoking -- Complications
KW  - Joint Commission
KW  - Prospective Studies
KW  - T-Tests
KW  - Mann-Whitney U Test
KW  - Chi Square Test
KW  - Fisher's Exact Test
KW  - Male
KW  - Female
KW  - Patient Attitudes
KW  - Adult
KW  - Middle Age
KW  - Aged
SP  - 92
EP  - 96 5p
JO  - Pharmacy Practice (18863655)
JF  - Pharmacy Practice (18863655)
JA  - PHARM PRACT
VL  - 10
IS  - 2
PB  - Centro de Investigaciones y Publicaciones Farmaceuticas S.L.
SN  - 1886-3655
AD  - Associate Professor, Department of Clinical Pharmacy, College of Pharmacy; and Department of Family Medicine, Graduate School of Medicine, University of Tennessee. Knoxville, TN (United States)
AD  - Clinical Staff Pharmacist, Department of Pharmacy, University of Tennessee Medical Center. Knoxville, TN (United States)
AD  - Associate Professor, Department of Family Medicine, Graduate School of Medicine, University of Tennessee, Knoxville, TN (United States)
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104355730&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104702876
T1  - Pharmacy student perceptions of public health service roles and responsibilities.
AU  - Wilbur, Kerry
Y1  - 2011/06//
N1  - Accession Number: 104702876. Language: English. Entry Date: 20111106. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. 
KW  - Students, Pharmacy
KW  - Student Attitudes -- Evaluation
KW  - Health Promotion
KW  - Professional Role
KW  - Public Health
KW  - Disease -- Prevention and Control
KW  - Human
KW  - Accountability
KW  - Qatar
KW  - Questionnaires
KW  - Breast Neoplasms -- Prevention and Control
KW  - Diabetes Mellitus -- Prevention and Control
KW  - Smoking -- Prevention and Control
KW  - Alcohol Abuse -- Prevention and Control
KW  - Asthma -- Prevention and Control
KW  - Cardiovascular Diseases -- Prevention and Control
SP  - 179
EP  - 184 6p
JO  - International Journal of Pharmacy Practice
JF  - International Journal of Pharmacy Practice
JA  - INT J PHARM PRACT
VL  - 19
IS  - 3
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 0961-7671
AD  - College of Pharmacy, Qatar University, Doha, Qatar
DO  - 10.1111/j.2042-7174.2011.00115.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104057137
T1  - Pharmacy Students' Attitudes About Treating Patients With Alcohol Addiction After Attending a Required Mutual Support Group.
AU  - Neville, Michael W.
Y1  - 2014/04//
N1  - Accession Number: 104057137. Language: English. Entry Date: 20140404. Revision Date: 20150710. Publication Type: Journal Article. Journal Subset: Biomedical; USA. 
SP  - 1
EP  - 5 5p
JO  - American Journal of Pharmaceutical Education
JF  - American Journal of Pharmaceutical Education
JA  - AM J PHARMACEUTICAL EDUC
VL  - 78
IS  - 2
CY  - Alexandria, Virginia
PB  - American Association of Colleges of Pharmacy
SN  - 0002-9459
AD  - College of Pharmacy, University of Georgia, Athens, Georgia
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104057137&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106405903
T1  - Physicians' attitude and practices in sickle cell disease pain management.
AU  - Labbé E
AU  - Herbert D
AU  - Haynes J
Y1  - 2005///2005 Winter
N1  - Accession Number: 106405903. Language: English. Entry Date: 20060310. Revision Date: 20150820. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Canada; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed. Instrumentation: Physician Attitudes Survey (Von Roenn et al) [adapted]. NLM UID: 8610345. 
KW  - Anemia, Sickle Cell -- Psychosocial Factors
KW  - Pain -- Psychosocial Factors
KW  - Physician Attitudes
KW  - Data Analysis Software
KW  - Data Analysis, Statistical
KW  - Descriptive Statistics
KW  - Female
KW  - Male
KW  - P-Value
KW  - Pain Measurement -- Psychosocial Factors
KW  - Pearson's Correlation Coefficient
KW  - Research Instruments
KW  - Spearman's Rank Correlation Coefficient
KW  - Substance Abuse -- Psychosocial Factors
KW  - Substance Dependence -- Psychosocial Factors
KW  - Survey Research
KW  - Human
SP  - 246
EP  - 251 6p
JO  - Journal of Palliative Care
JF  - Journal of Palliative Care
JA  - J PALLIAT CARE
VL  - 21
IS  - 4
CY  - Montreal, Quebec
PB  - Centre for Bioethics/Clinical Research
AB  - Many physicians believe that patients with sickle cell disease (SCD) are more likely to become addicted to pain medication than are other patient populations. This study hypothesizes that physicians' attitudes towards addiction in patients with SCD affects pain management practices. The Physician Attitudes Survey was sent to 286 physicians at seven National Institutes of Health-funded university-based comprehensive sickle cell centres. The survey assessed demographic information; and physician's attitudes toward and knowledge of pain, pain treatment, and drug addiction and abuse. Significant Pearson product-moment correlations were found between attitudes towards pain and beliefs regarding addiction to prescribed opioids. Physicians reported ,varied pain management strategies, however, many believe that attitudes toward addiction and to patients in pain crises may result in undertreatment of pain. These results indicate that physicians might benefit from additional education regarding sickle cell disease, addiction to pain medication, the pharmacology of opioids, and the assessment and treatment of pain.
SN  - 0825-8597
AD  - Dept of Psychology, University of South Alabama, Comprehensive Sickle Cell Center, Mobile, AL
U2  - PMID: 16483093.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106405903&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104365538
T1  - Physicians' beliefs about faith-based treatments for alcoholism.
AU  - Lawrence RE
AU  - Rasinski KA
AU  - Yoon JD
AU  - Koenig HG
AU  - Meador KG
AU  - Curlin FA
Y1  - 2012/06//
N1  - Accession Number: 104365538. Language: English. Entry Date: 20130111. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Psychiatry/Psychology. NLM UID: 9502838. 
KW  - Alcoholics Anonymous
KW  - Alcoholism -- Therapy
KW  - Attitude of Health Personnel
KW  - Physicians -- Psychosocial Factors
KW  - Religion and Religions
KW  - Adult
KW  - Aged
KW  - Drug Therapy
KW  - Female
KW  - Human
KW  - Male
KW  - Middle Age
KW  - Physicians, Family -- Psychosocial Factors
KW  - Psychiatry
KW  - Questionnaires
KW  - Socioenvironmental Therapy
KW  - Spirituality
SP  - 597
EP  - 604 8p
JO  - Psychiatric Services
JF  - Psychiatric Services
JA  - PSYCHIATR SERV
VL  - 63
IS  - 6
CY  - Arlington, Virginia
PB  - American Psychiatric Publishing, Inc.
AB  - OBJECTIVE: The study examined physicians' beliefs about faith-based alcohol treatments vis-à-vis Alcoholics Anonymous, pharmacologic treatment, and residential treatment. METHODS: A survey was mailed to a national sample of U.S. primary care physicians and psychiatrists. It included a brief vignette of a nominally religious 47-year-old man hospitalized for acute alcohol poisoning who requested addiction treatment. Physicians rated the likely effectiveness of three treatment methods: Alcoholics Anonymous, pharmacological therapy by an addiction specialist, and a residential program. Physicians were asked whether they would refer the patient to a faith-based program (beyond Alcoholics Anonymous) and whether an emphasis on spirituality is critical to 12-step program success. RESULTS: The response rate was 896 of 1,427 (63%) for primary care physicians and 312 of 487 (64%) for psychiatrists. Psychiatrists were more likely to rate Alcoholics Anonymous as very effective (64% versus 57% of primary care physicians), more likely to rate residential treatment as very effective (47% versus 38% of primary care physicians), and more likely to rate pharmacologic therapy as very effective (31% versus 22% of primary care physicians). Psychiatrists and primary care physicians were equally likely to consider referring the patient to a faith-based program (71% and 79%) and equally likely to believe that 'an emphasis on spirituality is critical to the success of 12-step programs' (81% and 85%). CONCLUSIONS: Psychiatrists were more optimistic than primary care physicians about all three treatments. Physicians in both specialties would refer even nominally religious patients to explicitly faith-based programs (beyond Alcoholics Anonymous). Physicians' enthusiasm for faith-based treatments highlights the need for scientific study of these treatments to determine which elements are most helpful for patients seeking recovery.
SN  - 1075-2730
AD  - Department of Psychiatry, Columbia University Medical Center, 1051 Riverside Dr., Box 103, New York, NY 10032, USA. rlawrence@uchicago.edu
U2  - PMID: 22476161.
DO  - 10.1176/appi.ps.201100315
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105531705
T1  - Plasticity of addiction: a mesolimbic dopamine short-circuit?
AU  - Niehaus JL
AU  - Cruz-Bermudez ND
AU  - Kauer JA
Y1  - 2009/07//
N1  - Accession Number: 105531705. Language: English. Entry Date: 20091002. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Psychiatry/Psychology. NLM UID: 9208821. 
KW  - Dopamine -- Metabolism
KW  - Nervous System -- Metabolism
KW  - Neuronal Plasticity -- Physiology
KW  - Substance Use Disorders -- Metabolism
KW  - Basal Ganglia -- Metabolism
KW  - Health Status
KW  - Learning
KW  - Memory
KW  - Nicotine -- Pharmacokinetics
KW  - Nicotinic Agonists -- Pharmacokinetics
KW  - Receptors, Cell Surface -- Metabolism
KW  - Recurrence
KW  - Reward
SP  - 259
EP  - 271 13p
JO  - American Journal on Addictions
JF  - American Journal on Addictions
JA  - AM J ADDICT
VL  - 18
IS  - 4
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - The development of drug addiction progresses along a continuum from acute drug use to compulsive use and drug seeking behavior. Many researchers have focused on identifying the physiological mechanisms involved in drug addiction in order to develop effective pharmacotherapies. Neuroplasticity, the putative mechanism underlying learning and memory, is modified by drugs of abuse and may contribute to the development of the eventual addicted state. Innovative treatments directly targeting these drug-induced changes in brain reward components and circuits may be efficacious in reducing drug use and relapse.
SN  - 1055-0496
AD  - Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, Rhode Island 02912, USA.
U2  - PMID: 19444729.
DO  - 10.1080/10550490902925946
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105531705&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109866135
T1  - Poisoning with illicit substances: toxicology for the anaesthetist.
AU  - Wong, G. T. C.
AU  - Irwin, M. G.
Y1  - 2013/02/02/
N1  - Accession Number: 109866135. Language: English. Entry Date: 20150623. Revision Date: 20150923. Publication Type: Journal Article; review. Journal Subset: Biomedical; Europe; UK & Ireland. 
KW  - Poisoning -- Therapy
KW  - Toxicology -- Education
KW  - Anesthetists -- Education
KW  - Fat Emulsions, Intravenous -- Therapeutic Use
KW  - Poisoning -- Diagnosis
KW  - Street Drugs -- Adverse Effects
KW  - Substance Abuse -- Complications
KW  - Imidazoles -- Therapeutic Use
KW  - Poisoning -- Drug Therapy
KW  - Adrenergic Agonists -- Therapeutic Use
SP  - 117
EP  - 124 8p
JO  - Anaesthesia Supplement
JF  - Anaesthesia Supplement
JA  - ANAESTHESIA SUPPL
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 1461-6904
AD  - Clinical Assistant Professor
AD  - Professor & Head, Department of Anaesthesiology, University of Hong Kong, Hong Kong; Chief of Service, Department of Anaesthesiology, Queen Mary Hospital, HKU-Shenzhen Hospital, Hong Kong
DO  - 10.1111/anae.12053
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105225116
T1  - Preparing pharmacy students and pharmacists to provide tobacco cessation counselling.
AU  - Williams DM
Y1  - 2009/09//
N1  - Accession Number: 105225116. Language: English. Entry Date: 20100604. Revision Date: 20150711. Publication Type: Journal Article; case study. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9015440. 
KW  - Counseling -- Education
KW  - Pharmacists -- Psychosocial Factors
KW  - Students, Pharmacy -- Psychosocial Factors
KW  - Smoking Cessation
KW  - Substance Use Disorders -- Psychosocial Factors
KW  - Adult
KW  - Counseling -- Methods
KW  - Female
KW  - Patient Education -- Methods
KW  - Professional-Patient Relations
KW  - Substance Use Disorders -- Diagnosis
KW  - Substance Use Disorders -- Therapy
SP  - 533
EP  - 540 8p
JO  - Drug & Alcohol Review
JF  - Drug & Alcohol Review
JA  - DRUG ALCOHOL REV
VL  - 28
IS  - 5
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 0959-5236
AD  - Division of Pharmacotherapy and Experimental Therapeutics, University of North Carolina Eshelman School of Pharmacy, Chapel Hill, NC 27599, USA. dwilliams@unc.edu
U2  - PMID: 19737211.
DO  - 10.1111/j.1465-3362.2009.00109.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106624996
T1  - Prescription for change: perspectives on prescribing authority for addiction nurses in the United Kingdom.
AU  - Rassool GH
Y1  - 2004/12//
N1  - Accession Number: 106624996. Language: English. Entry Date: 20050425. Revision Date: 20150820. Publication Type: Journal Article. Journal Subset: Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 9616159. 
KW  - Addictions Nursing
KW  - Clinical Competence
KW  - Nursing Role
KW  - Prescriptive Authority
KW  - Psychopharmacology -- Education
KW  - Addictions Nursing -- Education
KW  - Clinical Supervision
KW  - Education, Nursing, Continuing
KW  - Nursing Knowledge
KW  - Professional Development
KW  - Psychotropic Drugs -- Administration and Dosage
KW  - Scope of Nursing Practice
KW  - United Kingdom
SP  - 193
EP  - 197 5p
JO  - Journal of Addictions Nursing (Taylor & Francis Ltd)
JF  - Journal of Addictions Nursing (Taylor & Francis Ltd)
JA  - J ADDICT NURS (TAYLOR & FRANCIS LTD)
VL  - 15
IS  - 4
CY  - Philadelphia, Pennsylvania
PB  - Taylor & Francis Ltd
AB  - Nurses, pharmacists or other health professionals in England are now able to prescribe 'prescription only medicines' (POMs). This prescribing initiative has been extended to controlled drugs. Nurse prescribing has advantages for nurses and patients, including enhanced career development opportunities, nurse led-services and better quality of patient care. Future prescribing directions for addiction nurses would include prescribing for minor injuries, pain, nutritional supplements, antibiotics, emergency contraceptives, medications for detoxifications and psychotropic substances. Nurse prescribing, such as methadone for opiate dependence would significantly reduce the waiting time for service-users to gain access to appropriate services. However, there are issues of concerns such as the relationship between nurse prescribers and non-prescribers, and the relationship between nurse prescribers and medical supervisors, clinical supervision and ongoing professional support for nurse prescribers. This paper examines some perspectives on aspects of nurse prescribing with reference to addiction nursing in the UK, with selected literature reviews on nurse prescribing.
SN  - 1088-4602
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104190241
T1  - Prescription Patterns of Pain Medicine Physicians.
AU  - Benzon, Honorio T.
AU  - Kendall, Mark C.
AU  - Katz, Jeffrey A.
AU  - Benzon, Hubert A.
AU  - Malik, Khalid
AU  - Cox, Paul
AU  - Dean, Kathryn
AU  - Avram, Michael J.
Y1  - 2013/07//
N1  - Accession Number: 104190241. Language: English. Entry Date: 20130713. Revision Date: 20150711. Publication Type: Journal Article; algorithm; research; tables/charts. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Special Interest: Pain and Pain Management. NLM UID: 101130835. 
KW  - Prescribing Patterns -- Evaluation
KW  - Pain -- Drug Therapy
KW  - Physician Attitudes -- Evaluation
KW  - Medical Practice -- Evaluation
KW  - Specialties, Medical
KW  - Medical Organizations
KW  - Questionnaires
KW  - Drugs, Prescription -- Classification
KW  - Human
SP  - 440
EP  - 450 11p
JO  - Pain Practice
JF  - Pain Practice
JA  - PAIN PRACTICE
VL  - 13
IS  - 6
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Objectives Our study surveyed physician members of 3 American pain societies to determine prescription patterns and whether these practices reflect current expert opinion. Methods We sent 3 mailings to 2938 physicians from January 2010 to January 2011. The questionnaire contained 49 questions on topics related to opioids, antidepressants, anticonvulsants, and preferences for the different pain syndromes. Results A total of 474 physicians responded, representing a 16% return. Seventy-two percent ask patients to sign an opioid agreement, 59% order random urine drug testing, 13% wait until the dose of methadone is between 100 and 150 mg before converting the drug to another opioid, and 85% do not think there is a maximum dose of opioids with respect to driving. Most responders prescribe codeine to Caucasians and Asians. While 42% stated that the maximum daily dose of acetaminophen is 3000 mg, 75% would decrease the dose in patients who are moderate or heavy drinkers. Fifty-four percent do not order an ECG at all when prescribing tricyclic antidepressants. Conclusions The responses pertaining to opioid agreements, urine drug testing, acetaminophen, and treatment for neuropathic pain are reassuring in that they prevent misuse and abuse of opioids, prevent acetaminophen-induced hepatotoxicity, and reflect evidence-based treatments. However, we identified gaps in knowledge, including the prescription of codeine in certain populations and the use of electrocardiogram in patients on antidepressants. Further education of physicians who treat chronic pain pharmacologically is warranted.
SN  - 1530-7085
AD  - Department of Anesthesiology, Northwestern University Feinberg School of Medicine
AD  - Department of Anesthesiology, Boston Children's Hospital
AD  - Temecula Valley Anesthesiologist
AD  - Transitional Year, Department of Medicine, North Shore Hospital, University of Chicago
U2  - PMID: 23228095.
DO  - 10.1111/papr.12011
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104190241&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109739478
T1  - Prevalence and experience of chronic pain in suburban drug injectors.
AU  - Heimer, Robert
AU  - Zhan, Weihai
AU  - Grau, Lauretta E
Y1  - 2015/06//
N1  - Accession Number: 109739478. Language: English. Entry Date: 20150923. Revision Date: 20160109. Publication Type: journal article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology. Grant Information: R01 DA030420/DA/NIDA NIH HHS/United States. NLM UID: 7513587. 
SP  - 92
EP  - 100 9p
JO  - Drug & Alcohol Dependence
JF  - Drug & Alcohol Dependence
JA  - DRUG ALCOHOL DEPENDENCE
VL  - 151
PB  - Elsevier Science
AB  - Aims: To explore the relationship between chronic pain and characteristics, behaviors, and psychological status of suburban Connecticut injection drug users.Methods: Cross-sectional study with quantitative interview and serological testing for HIV and hepatitis B and C in 456 individuals who injected drugs in the past month. Participants were dichotomized into those reporting current chronic pain of at least six months duration and all others. The interview covered (i) sociodemographics, (ii) injection drug use, (iii) interactions with drug treatment, criminal justice, and harm reduction, (iv) screening for alcohol use, chronic pain, anxiety, and depression, and (v) knowledge regarding HIV, hepatitis B (HBV) and C (HCV), and opioid overdose. Serological testing for HIV, HBV, and HCV was conducted.Results: One-third (n = 143) reported chronic pain. These individuals differed significantly from those not reporting chronic pain on characteristics that included older age, lower educational achievement, and injection of pharmaceutical opioids. They also reported experiencing more psychological and family problems on the ASI and higher levels of depression and anxiety. Four of five individuals with chronic pain (n = 117) reported non-medical opioid use prior to the onset of chronic pain.Conclusions: Chronic pain is common among drug injectors in our study population although it was unusual for chronic pain to have preceded non-medical opioid use. Psychological problems in injectors with co-occurring chronic pain are likely pose significant complications to successful treatment for substance abuse, pain, or infectious disease treatment.
SN  - 0376-8716
U2  - PMID: 25841984.
DO  - 10.1016/j.drugalcdep.2015.03.007
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109739478&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106464298
T1  - Prevalence and predictors of research participant eligibility criteria in alcohol treatment outcome studies, 1970-98.
AU  - Humphreys K
AU  - Weingardt KR
AU  - Horst D
AU  - Joshi AA
AU  - Finney JW
Y1  - 2005/09//
N1  - Accession Number: 106464298. Language: English. Entry Date: 20060630. Revision Date: 20150711. Publication Type: Journal Article; research; systematic review; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Grant Information: Funded by NIAA grants R-O1 AA13315 and R-O1 AA08689, and by the Department of Veterans Affairs Health Services Research and Development Service and Mental Health Strategic Healthcare Group. NLM UID: 9304118. 
KW  - Alcoholism -- Therapy
KW  - Eligibility Determination
KW  - Research Subjects
KW  - Funding Source
KW  - Health Status
KW  - Kruskal-Wallis Test
KW  - Regression
KW  - Human
SP  - 1249
EP  - 1257 9p
JO  - Addiction
JF  - Addiction
JA  - ADDICTION
VL  - 100
IS  - 9
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - AIMS: To describe the eligibility criteria (i.e. study participant inclusion and exclusion rules) employed in alcohol treatment outcome research and to identify predictors of their use. DESIGN: The eligibility criteria of 683 alcohol treatment outcome studies conducted between 1970 and 1998 were coded reliably into 14 general categories. Predictors of the use of eligibility criteria were then examined. FINDINGS: Patients were most often ruled ineligible for research studies because of their level of alcohol problems (39.1% of studies), comorbid psychiatric problems (37.8%), past or concurrent utilization of alcohol treatment (31.8%), co-occurring medical conditions (31.6%), and because they were deemed non-compliant and unmotivated (31.5%). The number of eligibility criteria employed in studies increased from the 1970s through the 1990s, and was positively associated with funding from the US National Institute of Alcohol Abuse and Alcoholism (NIAAA) and from the private sector, lack of an inpatient/residential treatment condition, presence of a pharmacotherapy, and use of a randomized, multiple-condition design. Principal investigators with doctoral degrees used more eligibility criteria than those with lower degrees. CONCLUSION: Participant eligibility criteria are extensively employed in alcohol treatment outcome research, and vary significantly across historical periods, funders and research designs. Researchers should report the details of subject eligibility criteria and excluded patients more fully, and, evaluate how eligibility criteria affect the cost, feasibility, and generalizability of treatment outcome research.
SN  - 0965-2140
AD  - Program Evaluation and Resource Center, Veterans Affairs PAHCS (152-MPD), 795 Willow Road, Menlo Park, CA 94025
U2  - PMID: 16128714.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106464298&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104049374
T1  - Prevalence of Self-Reported Nonmedical Use of Prescription Stimulants in North Carolina Doctor of Pharmacy Students.
AU  - Volger, Emily J.
AU  - McLendon, Amber N.
AU  - Fuller, Stephen H.
AU  - Herring, Charles T.
Y1  - 2014/04//
N1  - Accession Number: 104049374. Language: English. Entry Date: 20140326. Revision Date: 20150710. Publication Type: Journal Article; questionnaire/scale; research; tables/charts. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 8900945. 
KW  - Students, Pharmacy
KW  - Substance Abuse -- Epidemiology -- North Carolina
KW  - Self Report
KW  - Central Nervous System Stimulants
KW  - North Carolina
KW  - Prospective Studies
KW  - Cross Sectional Studies
KW  - Human
KW  - Male
KW  - Female
KW  - Descriptive Statistics
KW  - Chi Square Test
KW  - Univariate Statistics
KW  - Multiple Logistic Regression
KW  - Step-Wise Multiple Regression
KW  - Data Analysis Software
KW  - Confidence Intervals
KW  - Adult
KW  - Odds Ratio
SP  - 158
EP  - 168 11p
JO  - Journal of Pharmacy Practice
JF  - Journal of Pharmacy Practice
JA  - J PHARM PRACT
VL  - 27
IS  - 2
CY  - Thousand Oaks, California
PB  - Sage Publications Inc.
SN  - 0897-1900
AD  - Department of Pharmacy Practice, Shenandoah University, Bernard J. Dunn School of Pharmacy, Winchester, VA, USA evolger@su.edu
AD  - Department of Pharmacy Practice, Campbell University College of Pharmacy and Health Sciences, Buies Creek, NC, USA
U2  - PMID: 24310525.
DO  - 10.1177/0897190013508139
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105235559
T1  - Principles of laboratory assessment of drug abuse liability and implications for clinical development.
AU  - Carter LP
AU  - Griffiths RR
Y1  - 2009/12/02/Dec2009 Supplement 1
N1  - Accession Number: 105235559. Language: English. Entry Date: 20100129. Revision Date: 20150711. Publication Type: Journal Article. Supplement Title: Dec2009 Supplement 1. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology. NLM UID: 7513587. 
KW  - Behavioral Research -- Methods
KW  - Clinical Trials -- Methods
KW  - Drug Evaluation -- Methods
KW  - Substance Use Disorders -- Prevention and Control
KW  - Animals
KW  - Risk Assessment -- Methods
SP  - S14
EP  - 25 1p
JO  - Drug & Alcohol Dependence
JF  - Drug & Alcohol Dependence
JA  - DRUG ALCOHOL DEPENDENCE
VL  - 105
PB  - Elsevier Science
AB  - Abuse liability testing plays an important role in informing drug development, regulatory processes, and clinical practice. This paper describes the current 'gold standard' methodologies that are used for laboratory assessments of abuse liability in non-human and human subjects. Particular emphasis is given to procedures such as non-human drug discrimination, self-administration, and physical dependence testing, and human dose-effect abuse liability studies that are commonly used in regulatory submissions to governmental agencies. The potential benefits and risks associated with the inclusion of measures of abuse liability in industry-sponsored clinical trials is discussed. Lastly, it is noted that many factors contribute to patterns of drug abuse and dependence outside of the laboratory setting and positive or negative signals in abuse liability studies do not always translate to high or low levels of actual abuse or dependence. Well-designed patient and physician education, pharmacovigilance, and postmarketing surveillance can reduce the diversion and misuse of drugs with abuse liability and can effectively foster the protection and promotion of public health.
SN  - 0376-8716
AD  - Department of Psychiatry, University of Arkansas for Medical Sciences, Psychiatric Research Institute-Center for Addiction Research, Little Rock, AR 72205, United States.
U2  - PMID: 19443137.
DO  - 10.1016/j.drugalcdep.2009.04.003
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105852376
T1  - Process for preventing or identifying and resolving problems in drug therapy.
AU  - Robertson KE
Y1  - 1996/03/15/1996 Mar 15
N1  - Accession Number: 105852376. Language: English. Entry Date: 20080314. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. Instrumentation: Learning Style Inventory (LSI) (Kolb). NLM UID: 9503023. 
KW  - Drug Therapy -- Standards
KW  - Pharmacy Service -- Standards
KW  - Problem Solving
KW  - Process Assessment (Health Care)
KW  - Drug Therapy -- Economics
KW  - Education, Medical
KW  - Hospitals, Community
KW  - Indiana
KW  - Pharmacists
KW  - Quality Assurance
KW  - Staff Development
KW  - Study Design
KW  - Human
SP  - 639
EP  - 650 12p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 53
IS  - 6
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
AB  - A consistent process for preventing or identifying and resolving problems related to drug therapy is described. The process was originally developed to help pharmacy students focus on drug therapy issues during their clinical clerkship rotations. The first version of this approach to quality improvement consisted of lists of questions designed to prompt the student to prevent or identify and correct drug therapy problems. Because the learning style of some students is more visual, the questions were incorporated into flow charts. Students at a community hospital used the flow charts during their rotations through the critical care, medical-surgical, and psychiatric units, and the process appeared to result in improvements in the quality of care and in savings in the cost of care. As a result, a staff development and training project was begun to determine if staff pharmacists who use this process to evaluate drug therapy will begin to provide pharmaceutical care. This sort of transitional model of pharmaceutical care may expedite global implementation of the new practice philosophy. Flow charts encouraging a uniform approach to the prevention or identification and correction of drug therapy problems were developed for use by pharmacy students and generalist pharmacists.
SN  - 1079-2082
AD  - Ribordy Center for Community Pharmacy Practice, College of Pharmacy and Health Sciences, Butler University, Indianapolis, IN 46208, USA. robertson@butler.edu
U2  - PMID: 8800969.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105852376&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107052771
T1  - Professional issues. Hospital nurses' perceptions of pharmacist prescribing.
AU  - Child D
Y1  - 2001/01/11/
N1  - Accession Number: 107052771. Language: English. Entry Date: 20010921. Revision Date: 20150820. Publication Type: Journal Article; research; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 9212059. 
KW  - Nurse Attitudes
KW  - Pharmacists
KW  - Prescriptive Authority
KW  - Questionnaires
KW  - Mail
KW  - Pilot Studies
KW  - Descriptive Statistics
KW  - Academic Medical Centers
KW  - Qualitative Studies
KW  - United Kingdom
KW  - Human
SP  - 48
EP  - 54 7p
JO  - British Journal of Nursing
JF  - British Journal of Nursing
JA  - BR J NURS
VL  - 10
IS  - 1
PB  - MA Healthcare Limited
AB  - The final report from the Crown review team was published in March 1999. It proposed that new groups of healthcare professionals should be permitted to prescribe medicines. Most of the recent progress has centred on the extension of community nurse prescribing. However, changes have also been proposed to prescribing practices within the hospital setting to include nurses, pharmacists, and other healthcare professionals. This study is an initial piece of work examining hospital nurses' perceptions of pharmacist prescribing to identify if there are issues that warrant further investigation. Postal questionnaires, seeking responses to statements describing pharmacists writing prescriptions for drug treatment, were sent to 200 nurses at five NHS teaching hospitals in Birmingham. Completed questionnaires were received from 115 nurses (a response rate of 57.5%). Fifty-four respondents added comments to the questionnaire, giving some insight into their responses to the statements on pharmacist prescription-writing and prescribing. These comments indicated five key issues that may warrant further investigation: (1) pharmacists' knowledge of the patient (2) doctors losing the opportunity to review drug treatment (3) potential communication problems (4) pharmacists' workload, and (5) legal and professional accountability.
SN  - 0966-0461
AD  - Principal Pharmacist, Clinical Services, South Manchester University Hospitals NHS Trust
U2  - PMID: 12170485.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107052771&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106475582
T1  - Psychopathology is associated with completion of residential treatment in drug dependent women.
AU  - Haller DL
AU  - Miles DR
Y1  - 2004/03//
N1  - Accession Number: 106475582. Language: English. Entry Date: 20050701. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Millon Clinical Multiaxial Inventory-III (MCMI-III). Grant Information: Center for Substance Abuse Treatment (HS4 TI00555) and the National Institutes of Health, Building Research Careers in Women's Health (DA 14041). NLM UID: 9107051. 
KW  - Mental Disorders -- In Pregnancy
KW  - Psychopathology -- In Pregnancy
KW  - Substance Abuse, Perinatal -- Therapy
KW  - Substance Dependence -- Therapy -- In Pregnancy
KW  - Adolescence
KW  - Adult
KW  - Analysis of Variance
KW  - Cluster Analysis
KW  - Data Analysis Software
KW  - Female
KW  - Fisher's Exact Test
KW  - Kaplan-Meier Estimator
KW  - Log-Rank Test
KW  - Multivariate Analysis of Variance
KW  - Patient Compliance
KW  - Pregnancy
KW  - Psychological Tests
KW  - Questionnaires
KW  - Structured Interview
KW  - Substance Use Rehabilitation Programs
KW  - Funding Source
KW  - Human
SP  - 17
EP  - 28 12p
JO  - Journal of Addictive Diseases
JF  - Journal of Addictive Diseases
JA  - J ADDICT DIS
VL  - 23
IS  - 1
PB  - Taylor & Francis Ltd
AB  - This study characterized drug dependent women based on current psychopathology (MCMI-III) and then examined the relationship between psychopathology and treatment retention. Participants included 97 pregnant (88%), African-American (78%), single (90%) 30-year old women enrolled in a 6-month residential drug treatment program for women and children. Clustering on personality test scores using Ward's technique identified three subgroups with mild (24%), moderate (59%) and severe (18%) psychopathology. Treatment completion rates varied by group (66%, 45% and 29%), with half of the high severity group leaving against medical advice (AMA) within 60 days. Although the majority of low severity women completed the program as scheduled, they may also have done well in a less intensive treatment modality. Conversely, it appears that women with severe psychopathology may require a more flexible, psychiatrically-oriented approach than is found in most residential settings including greater emphasis on psychiatric issues, individual psychotherapy, and pharmacotherapy.
SN  - 1055-0887
AD  - Director of Research, Dept of Psychiatry, St Luke's Roosevelt Hospital Center, 1090 Amsterdam Ave, Suite 16F, New York, NY 10025; dhaller@chpnet.org
U2  - PMID: 15077837.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106475582&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106682272
T1  - Psychopharmacology of adults with attention-deficit/hyperactivity disorder.
AU  - Biederman J
AU  - Spencer TJ
Y1  - 2004/07//2004 Jul
N1  - Accession Number: 106682272. Language: English. Entry Date: 20040827. Revision Date: 20150711. Publication Type: Journal Article; CEU; exam questions; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9602353. 
KW  - Attention Deficit Hyperactivity Disorder -- Drug Therapy -- In Adulthood
KW  - Adult
KW  - Delayed-Action Preparations
KW  - Dextroamphetamine -- Therapeutic Use
KW  - Education, Continuing (Credit)
KW  - Methylphenidate -- Therapeutic Use
SP  - 57
EP  - 74 8p
JO  - Primary Psychiatry
JF  - Primary Psychiatry
JA  - PRIM PSYCHIATRY
VL  - 11
IS  - 7
CY  - New York, New York
PB  - MBL Communications
AB  - Although frequently unrecognized, as many as 4% of adults in the general population may have attention-deficit/hyperactivity disorder (ADHD). Increased public awareness is leading many adults to their family physician for treatment. While education about the disorder and specific counseling can be a great help, pharmacotherapy is the key to achieving control of the core symptoms of ADHD in most patients. This article reviews the available data for the pharmacologic treatment of adults with ADHD. Methylphenidate (MPH) is the most studied treatment for ADHD, with response rates exceeding 70% when dosed optimally. A similar response rate has been reported for dextroamphetamines. Both stimulants have a well-established safety profile from extensive experience in children, and are well tolerated in adults as well. The recently introduced extended-release stimulant formulations, OROS MPH and the mixed amphetamine salt Adderall XR, achieve symptom control for </=12 hours following administration of a single dose. Promising preliminary results suggest that these formulations would be the treatment of choice for adults. The nonstimulant atomoxetine has also demonstrated efficacy in adults with ADHD and may be an appropriate alternative in patients unresponsive to stimulant therapy, or in whom substance abuse or tics are of concern. However, atomoxetine requires twice/day dosing in most adults and has a less well-proven efficacy and safety profile.
SN  - 1082-6319
AD  - WACC 725, Pediatric Psychopharmacology Research Unit, Massachusetts General Hospital, Harvard Medical School, 15 Parkman St, Boston, MA 02114
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106682272&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107789482
T1  - Public and Policy Maker Support for Point-of-Sale Tobacco Policies in New York.
AU  - Schmitt, Carol L
AU  - Juster, Harlan R
AU  - Dench, Daniel
AU  - Willett, Jeffrey
AU  - Curry, Laurel E
Y1  - 2014/01//Jan/Feb2014
N1  - Accession Number: 107789482. Language: English. Entry Date: 20150508. Revision Date: 20150712. Publication Type: Journal Article; research. Journal Subset: Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Health Promotion/Education; Peer Reviewed; USA. NLM UID: 8701680. 
KW  - Administrative Personnel -- Statistics and Numerical Data
KW  - Public Opinion
KW  - Public Policy
KW  - Tobacco Products
KW  - Adult
KW  - Age Factors
KW  - Aged
KW  - Cross Sectional Studies
KW  - Female
KW  - Human
KW  - Male
KW  - Middle Age
KW  - New York
KW  - Sex Factors
KW  - Smoking -- Prevention and Control
KW  - Young Adult
SP  - 175
EP  - 180 6p
JO  - American Journal of Health Promotion
JF  - American Journal of Health Promotion
JA  - AM J HEALTH PROMOT
VL  - 28
IS  - 3
CY  - Thousand Oaks, California
PB  - Sage Publications Inc.
AB  - Abstract Purpose. To compare public and policy maker support for three point-of-sale tobacco policies. Design. Two cross-sectional surveys-one of the public from the New York Adult Tobacco Survey and one of policy makers from the Local Opinion Leader Survey; both collected and analyzed in 2011. Setting. Tobacco control programs focus on educating the public and policy makers about tobacco control policy solutions. Subjects. Six hundred seventy-six county-level legislators in New York's 62 counties and New York City's five boroughs (response rate: 59%); 7439 New York residents aged 18 or older. Landline response rates: 20.2% to 22%. Cell phone response rates: 9.2% to 11.1%. Measures. Gender, age, smoking status, presence of a child aged 18 years or younger in the household, county of residence, and policy maker and public support for three potential policy solutions to point-of-sale tobacco marketing. Analysis. t-tests to compare the demographic makeup for the two samples. Adjusted Wald tests to test for differences in policy support between samples. Results. The public was significantly more supportive of point-of-sale policy solutions than were policy makers: cap on retailers (48.0% vs. 19.2%, respectively); ban on sales at pharmacies (49.1% vs. 38.8%); and ban on retailers near schools (53.3% vs. 42.5%). Limitations: cross-sectional data, sociodemographic differences, and variations in item wording. Conclusions Tobacco control programs need to include information about implementation, enforcement, and potential effects on multiple constituencies (including businesses) in their efforts to educate policy makers about point-of-sale policy solutions.
SN  - 0890-1171
U2  - PMID: 23875981.
DO  - 10.4278/ajhp.121023-QUAN-514
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104434521
T1  - Public knowledge and awareness of cardiovascular disease and its risk factors: a cross-sectional study of 1000 Jordanians.
AU  - Mukattash, Tareq L.
AU  - Shara, Mohd
AU  - Jarab, Anan S.
AU  - Al-Azzam, Sayer I
AU  - Almaaytah, Ammar
AU  - Al Hamarneh, Yazid N.
Y1  - 2012/12//
N1  - Accession Number: 104434521. Language: English. Entry Date: 20121108. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. 
KW  - Patient Education
KW  - Health Knowledge -- Education
KW  - Heart Diseases -- Risk Factors
KW  - Pharmacy and Pharmacology
KW  - Cross Sectional Studies
KW  - Jordan
KW  - Cardiovascular Diseases -- Mortality
KW  - Cardiovascular Diseases -- Prevention and Control
KW  - Coronary Disease -- Diagnosis
KW  - Literature Review
KW  - Questionnaires
KW  - Demography
KW  - Male
KW  - Female
KW  - Education
KW  - Age Factors -- Evaluation
KW  - Smoking -- Evaluation
KW  - Cardiovascular Diseases -- Familial and Genetic
KW  - Obesity -- Evaluation
KW  - Life Style
KW  - Diet
KW  - Exercise
KW  - Cardiovascular Diseases -- Diagnosis
KW  - Pharmacists
KW  - Human
SP  - 367
EP  - 376 10p
JO  - International Journal of Pharmacy Practice
JF  - International Journal of Pharmacy Practice
JA  - INT J PHARM PRACT
VL  - 20
IS  - 6
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
SN  - 0961-7671
AD  - Department of Clinical Pharmacy, Faculty of Pharmacy
AD  - Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan
AD  - Department of Pharmaceutical Technology, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid
AD  - Epicore Centre, University of Alberta, Edmonton, Alberta, Canada
DO  - 10.1111/j.2042-7174.2012.00208.x
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104434521&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106270012
T1  - Recent trends in adolescent substance use, primary care screening, and updates in treatment options.
AU  - Fournier ME
AU  - Levy S
Y1  - 2006/08//
N1  - Accession Number: 106270012. Language: English. Entry Date: 20070420. Revision Date: 20150711. Publication Type: Journal Article; review. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Pediatric Care. NLM UID: 9000850. 
KW  - Primary Health Care -- Trends
KW  - Substance Abuse Detection -- Trends
KW  - Substance Use Disorders -- Diagnosis
KW  - Substance Use Disorders -- Therapy
KW  - Adolescence
KW  - Ambulatory Care -- Trends
KW  - Behavior, Addictive -- Diagnosis
KW  - Behavior, Addictive -- Epidemiology
KW  - Behavior, Addictive -- Etiology
KW  - Behavior, Addictive -- Therapy
KW  - Counseling -- Trends
KW  - Substance Use Disorders -- Epidemiology
KW  - Substance Use Disorders -- Etiology
KW  - Substance Use Rehabilitation Programs -- Trends
KW  - United States
SP  - 352
EP  - 358 7p
JO  - Current Opinion in Pediatrics
JF  - Current Opinion in Pediatrics
JA  - CURR OPIN PEDIATR
VL  - 18
IS  - 4
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - Purpose of review: To provide a brief overview on trends in common substances of abuse in adolescents, a summary of tools to evaluate adolescent substance abuse in an outpatient setting, and an update of outpatient and inpatient treatment options.Recent findings: Recent national data suggest an overall slight decline in the use of tobacco, crystal methamphetamine, heroin, and club drugs. No significant change was noted in the use of alcohol, marijuana, and cocaine. Yearly screening of all adolescents for substance use is recommended. This can be accomplished in an office setting using mnemonics, structured interview techniques, and brief screens for substance abuse. If a problem is identified, various outpatient and inpatient treatments are available. Individual, family, and group therapy methods are available. Other options include acute detoxification programs, partial hospitalization, acute residential treatment, residential treatment centers and wilderness programs. Pharmacological treatments are available for nicotine, alcohol, and opioid addiction.Summary: Tobacco, alcohol, marijuana, and other drugs remain a significant problem among adolescents in the United States. Pediatricians should screen and assess all adolescents on a yearly basis. If a problem is identified, there are many options for treatment, including pharmacologic treatment as well as individual, family, or group therapy in an inpatient or outpatient setting.
SN  - 1040-8703
AD  - Division of Adolescent/Young Adult Medicine, Children's Hospital Boston, 300 Longwood Avenue, Boston, MA 02115; Mary.Fournier@childrens.harvard.edu
U2  - PMID: 16914986.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106270012&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106654749
T1  - Recommendations for the treatment of nicotine dependency.
AU  - Montalto NJ
Y1  - 2002/06//2002 Jun
N1  - Accession Number: 106654749. Language: English. Entry Date: 20041022. Revision Date: 20150711. Publication Type: Journal Article; algorithm; CEU; exam questions; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 7503065. 
KW  - Nicotine
KW  - Substance Dependence -- Therapy
KW  - Education, Continuing (Credit)
KW  - Practice Guidelines
KW  - Information Resources
SP  - 342
EP  - 355 9p
JO  - JAOA: Journal of the American Osteopathic Association
JF  - JAOA: Journal of the American Osteopathic Association
JA  - JAOA J AM OSTEOPATH ASSOC
VL  - 102
IS  - 6
CY  - Chicago, IL 60611, Illinois
PB  - American Osteopathic Association
AB  - The US Public Health Service (PHS) Clinical Practice Guideline Treating Tobacco Use and Dependence, published in June 2000, is a clinician-targeted resource that encourages physicians to apply evidence-based interventions when treating tobacco-dependent patients. Issued by the PHS Surgeon General, the guideline recommends a new standard of care in treating tobacco dependency, the chief cause of preventable death and disease in the United States. It calls on clinicians to more consistently identify and evaluate tobacco-dependent patients and to provide treatment, motivation to quit, and referrals to smoking cessation specialists. The guideline also serves as a mandate for healthcare insurers to offer pharmacologic and behavioral treatment modalities as benefits to insured persons and to provide education and reimbursement for clinicians.
SN  - 0098-6151
AD  - Associate Professor of Family Medicine, West Virginia University/Charleston Division, Charleston, WV; norman.montalto@camc.org
U2  - PMID: 12090652.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106654749&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 108066266
T1  - Recovering substance-impaired pharmacists' views regarding occupational risks for addiction.
AU  - Merlo LJ
AU  - Cummings SM
AU  - Cottler LB
Y1  - 2012/07//Jul/Aug2012
N1  - Accession Number: 108066266. Language: English. Entry Date: 20130111. Revision Date: 20150712. Publication Type: Journal Article; research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 101176252. 
KW  - Attitude of Health Personnel
KW  - Behavior, Addictive -- Psychosocial Factors
KW  - Attitude to Health
KW  - Occupational Diseases -- Psychosocial Factors
KW  - Pharmacists
KW  - Substance Use Disorders -- Psychosocial Factors
KW  - Adult
KW  - Aged
KW  - Behavior, Addictive -- Etiology
KW  - Behavior, Addictive -- Prevention and Control
KW  - Cross Sectional Studies
KW  - Female
KW  - Human
KW  - Male
KW  - Middle Age
KW  - Occupational Diseases -- Etiology
KW  - Occupational Diseases -- Prevention and Control
KW  - Drugs, Prescription -- Adverse Effects
KW  - Risk Factors
KW  - Students, Pharmacy
KW  - Substance Use Disorders -- Etiology
KW  - Substance Use Disorders -- Prevention and Control
SP  - 480
EP  - 491 12p
JO  - Journal of the American Pharmacists Association: JAPhA
JF  - Journal of the American Pharmacists Association: JAPhA
JA  - J AM PHARM ASSOC
VL  - 52
IS  - 4
CY  - Washington, District of Columbia
PB  - American Pharmacists Association
SN  - 1544-3191
U2  - PMID: 22825228.
DO  - 10.1331/JAPhA.2012.10214
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=108066266&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106550305
T1  - Registered nurses' knowledge of pharmacological concepts related to the management of postoperative pain in adults.
AU  - Spencer R
Y1  - 1996/01//
N1  - Accession Number: 106550305. Language: English. Entry Date: 20051209. Revision Date: 20150711. Publication Type: Journal Article; abstract; research. Journal Subset: Australia & New Zealand; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed. 
KW  - Nursing Knowledge -- Evaluation
KW  - Pharmacy and Pharmacology
KW  - Postoperative Pain -- Drug Therapy
KW  - Content Validity
KW  - Face Validity
KW  - Questionnaires
KW  - Human
SP  - 2p
EP  - 2p 1p
JO  - Nursing Monograph
JF  - Nursing Monograph
JA  - NURS MONOGR
PB  - St. Vincent's Hospital Sydney, Australian Catholic University Nursing Research Institute
AB  - This study investigated registered nurses knowledge of pharmacological concepts related to the management of postoperative pain in adults. To measure this knowledge a valid and reliable research instrument was developed.The process of instrument development included conducting a survey to ascertain what experts in the field of acute pain management believed registered nurses should know about pharmacology in order to effectively manage postoperative pain. The information from the survey was used to formulate a questionnaire which assessed for face and content validity and a field test was undertaken. A pilot study was conducted and the data was used to assess the reliability of the questionnaire. The questionnaire was then applied to a sample of registered nurses to measure their knowledge of pharmacological concepts related to postoperative pain.Findings showed that registered nurses in the sample lacked knowledge of many pharmacological concepts deemed important by pain management experts. The most outstanding were concepts related to mechanisms and duration of action of drugs, pethidine toxicity and the daily dosage range of paracetamol. An encouraging result was that registered nurses' knowledge of addiction may be improving in the postoperative setting. The findings also demonstrated that neither years of experience in a postoperative setting nor attendance at pain management education sessions in the last five years had any significant bearing on registered nurses overall knowledge scores.The results indicate the need for further pain management education for registered nurses. In particular, basic pharmacological principles need to be addressed in both undergraduate and continuing nursing education. To improve pain management practices, registered nurses' knowledge of important pharmacological concepts need to be improved.
SN  - 1328-6137
AD  - Intensive Therapy Unit, St. Vincent's Hospital
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106550305&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107503292
T1  - Rehabilitation in brain disorders. Intervention strategies... part 3.
AU  - Cobble ND
AU  - Bontke CF
AU  - Brandstater ME
AU  - Horn LJ
Y1  - 1991/03/16/1991 Mar Study Guide Issue
N1  - Accession Number: 107503292. Language: English. Entry Date: 19910701. Revision Date: 20150712. Publication Type: Journal Article; teaching materials. Supplement Title: 1991 Mar Study Guide Issue. Journal Subset: Allied Health; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 2985158R. 
KW  - Brain Diseases -- Rehabilitation
SP  - S324
EP  - 31 1p
JO  - Archives of Physical Medicine & Rehabilitation
JF  - Archives of Physical Medicine & Rehabilitation
JA  - ARCH PHYS MED REHABIL
VL  - 72
IS  - 4-S
CY  - Philadelphia, Pennsylvania
PB  - W B Saunders
AB  - This self-directed learning module highlights advances in the principles of management of brain disorders. It is part of the chapter on rehabilitation in brain disorders for the Self-Directed Medical Knowledge Program Study Guide for practitioners and trainees in physical medicine and rehabilitation. The chapter is composed of four articles, and each builds on principles established in the others. This article covers rehabilitation philosophy, management of cognitive remediation, and behavioral management, with attention to communication disorders, social factors, vocational/educational/avocational issues, treatment of motor deficits, dysphagia, sensory dysfunction, sexual dysfunction, and substance abuse. Advances that are covered in this section include pharmacologic and rehabilitative interventions for acute, chronic, and progressive brain injuries and diseases. The learner is directed to articles 1, 2, and 4 in this chapter for supporting information.
SN  - 0003-9993
U2  - PMID: 2003765.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107503292&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105051503
T1  - Report of the 2010 APhA House of Delegates.
Y1  - 2010/07//Jul/Aug2010
N1  - Accession Number: 105051503. Language: English. Entry Date: 20101126. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 101176252. 
KW  - Pharmacists -- Ethical Issues
KW  - Pharmacists -- Legislation and Jurisprudence
KW  - Professional Practice -- Standards
KW  - Professional Role
KW  - Professional Organizations
KW  - Advertising
KW  - Education, Pharmacy
KW  - Education, Pharmacy -- Standards
KW  - Prescriptions, Drug -- Standards
KW  - Government Regulations
KW  - Health Promotion -- Methods
KW  - Medical Records, Personal
KW  - Medicine
KW  - Genetics -- Methods
KW  - Professional Practice -- Trends
KW  - Substance Use Disorders
KW  - Industry -- Economics
KW  - Industry -- Ethical Issues
KW  - United States
SP  - 471
EP  - 472 2p
JO  - Journal of the American Pharmacists Association: JAPhA
JF  - Journal of the American Pharmacists Association: JAPhA
JA  - J AM PHARM ASSOC
VL  - 50
IS  - 4
CY  - Washington, District of Columbia
PB  - American Pharmacists Association
SN  - 1544-3191
U2  - PMID: 20621862.
DO  - 10.1331/JAPhA.2010.10525
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105051503&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104338159
T1  - Report of the AACP Special Committee on Substance Abuse and Pharmacy Education.
AU  - Jungnickel, Paul W.
AU  - DeSimone, Edward M.
AU  - Kissack, Julie C.
AU  - Lawson, Lisa A.
AU  - Murawski, Matthew M.
AU  - Patterson, Brandon J.
AU  - Rospond, Raylene M.
AU  - Scott, David M.
AU  - Athay, Jennifer
Y1  - 2010/12/15/
N1  - Accession Number: 104338159. Language: English. Entry Date: 20130301. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; USA. 
SP  - 1
EP  - 4 4p
JO  - American Journal of Pharmaceutical Education
JF  - American Journal of Pharmaceutical Education
JA  - AM J PHARMACEUTICAL EDUC
VL  - 74
IS  - 10
CY  - Alexandria, Virginia
PB  - American Association of Colleges of Pharmacy
SN  - 0002-9459
AD  - Harrison School of Pharmacy, Auburn University
AD  - School of Pharmacy and Allied Health Professions, Creighton University
AD  - College of Pharmacy, Harding University
AD  - Philadelphia College of Pharmacy, University of the Sciences in Philadelphia
AD  - School of Pharmacy and Pharmaceutical Sciences, Purdue University
AD  - College of Pharmacy, The University of Iowa
AD  - College of Pharmacy and Health Sciences, Drake University
AD  - College of Pharmacy, Nursing and Allied Sciences, North Dakota State University
AD  - American Association of Colleges of Pharmacy
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104338159&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103784108
T1  - Retention in Care and Medication Adherence: Current Challenges to Antiretroviral Therapy Success.
AU  - Holtzman, Carol
AU  - Brady, Kathleen
AU  - Yehia, Baligh
Y1  - 2015/04//
N1  - Accession Number: 103784108. Language: English. Entry Date: 20150402. Revision Date: 20150928. Publication Type: Journal Article; tables/charts. Journal Subset: Australia & New Zealand; Biomedical; Peer Reviewed. Special Interest: Public Health. Grant Information: BRY was supported by the National Institutes of Health (K23-MH097647).. NLM UID: 7600076. 
KW  - Anti-Retroviral Agents
KW  - Patient Compliance
KW  - Behavior
KW  - Strategic Planning
KW  - Funding Source
SP  - 445
EP  - 454 10p
JO  - Drugs
JF  - Drugs
JA  - DRUGS
VL  - 75
IS  - 5
PB  - Springer Science & Business Media B.V.
AB  - Health behaviors such as retention in HIV medical care and adherence to antiretroviral therapy (ART) pose major challenges to reducing new HIV infections, addressing health disparities, and improving health outcomes. Andersen's Behavioral Model of Health Service Use provides a conceptual framework for understanding how patient and environmental factors affect health behaviors and outcomes, which can inform the design of intervention strategies. Factors affecting retention and adherence among persons with HIV include patient predisposing factors (e.g., mental illness, substance abuse), patient-enabling factors (e.g., social support, reminder strategies, medication characteristics, transportation, housing, insurance), and healthcare environment factors (e.g., pharmacy services, clinic experiences, provider characteristics). Evidence-based recommendations for improving retention and adherence include (1) systematic monitoring of clinic attendance and ART adherence; (2) use of peer or paraprofessional navigators to re-engage patients in care and help them remain in care; (3) optimization of ART regimens and pharmaceutical supply chain management systems; (4) provision of reminder devices and tools; (5) general education and counseling; (6) engagement of peer, family, and community support groups; (7) case management; and (8) targeting patients with substance abuse and mental illness. Further research is needed on effective monitoring strategies and interventions that focus on improving retention and adherence, with specific attention to the healthcare environment.
SN  - 0012-6667
AD  - ICAP, Columbia University Mailman School of Public Health, Maseru 100 Lesotho
U2  - PMID: 25792300.
DO  - 10.1007/s40265-015-0373-2
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103784108&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106216767
T1  - Review: existing evidence does not support behavioural or other specific interventions to prevent smoking relapse.
AU  - Mohide EA
Y1  - 2006/10//
N1  - Accession Number: 106216767. Language: English. Entry Date: 20070119. Revision Date: 20150820. Publication Type: Journal Article; abstract; commentary; tables/charts. Original Study: Lancaster T, Hajek P, Stead LF et al. Prevention of relapse after quitting smoking: a systematic review of trials. ARCH INTERN MED 2006; 166: 828-35. Journal Subset: Core Nursing; Europe; Nursing; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice. NLM UID: 9815947. 
KW  - Behavior Therapy
KW  - Recurrence -- Prevention and Control
KW  - Smoking Cessation
KW  - Smoking -- Prevention and Control
KW  - Clinical Trials
KW  - Systematic Review
KW  - Treatment Outcomes
SP  - 109
EP  - 109 1p
JO  - Evidence Based Nursing
JF  - Evidence Based Nursing
JA  - EVID BASED NURS
VL  - 9
IS  - 4
PB  - BMJ Publishing Group
AB  - Are smoking relapse prevention interventions effective in people who have recently quit smoking?METHODSData sources: Cochrane Tobacco Addiction Review Group register of trials, which included the results of searches of Medline, PsycINFO, and conference abstracts (all to Aug 2005).Study selection and assessment: randomised or quasi-randomised controlled trials of participants who had quit smoking on their own, were in enforced abstinence, or were in cessation programmes; had >/=6 months of follow up; and compared relapse prevention interventions with no intervention, a shorter intervention, or an intervention not oriented toward relapse prevention. 42 trials (n = 30 580) met the selection criteria. Relapse prevention interventions included behavioural strategies and pharmacotherapy. Intensive behavioural intervention involved repeated face to face contact aimed at teaching people to identify tempting situations and apply coping and cognitive strategies to resist relapse. Less intensive interventions included written materials and brief face to face or telephone contacts.Outcomes: smoking abstinence at follow up (>/=6 mo).MAIN RESULTSMost analyses showed no difference between relapse prevention interventions and control conditions for smoking abstinence (table).CONCLUSIONExisting evidence does not support the effectiveness of behavioural or other specific interventions for prevention of relapse in people who have successfully quit smoking.
SN  - 1367-6539
AD  - School of Nursing, McMaster University, Hamilton, Ontario, Canada
U2  - PMID: 17076011.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106216767&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105727331
T1  - Risk practices and other characteristics of injecting drug users who obtain injecting equipment from pharmacies and personal networks.
AU  - Bryant J
AU  - Treloar C
Y1  - 2006/09//
N1  - Accession Number: 105727331. Language: English. Entry Date: 20080530. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Public Health. Grant Information: NSW HIV/AIDS Health Promotion Demonstration Project Grant (NSW Health). NLM UID: 9014759. 
KW  - Risk Factors
KW  - Substance Abuse
KW  - Australia
KW  - Chi Square Test
KW  - Data Analysis Software
KW  - Funding Source
KW  - Harm Reduction
KW  - Logistic Regression
KW  - Odds Ratio
KW  - Pharmacy, Retail
KW  - Sex Factors
KW  - Human
SP  - 418
EP  - 424 7p
JO  - International Journal of Drug Policy
JF  - International Journal of Drug Policy
JA  - INT J DRUG POLICY
VL  - 17
IS  - 5
CY  - New York, New York
PB  - Elsevier Science
AB  - Most of what is known about injecting drug users in Australia is based on those who attend formal harm reduction services. Little is known about those who primarily use other sources to obtain injecting equipment. This paper examines key characteristics and risk practices amongst two groups of Australian injectors: (1) those that obtain sterile equipment primarily through pharmacies; and (2) the more 'hidden' group of those that obtain equipment from their personal networks. A convenience sample of 227 recent injectors who identified either pharmacies (n = 167) or personal networks (n = 60) as their regular source of sterile needles and syringes completed an interviewer-administered structured questionnaire. Results show that respondents who obtained equipment from their personal networks reported similar rates of reusing needles and syringes as pharmacy attenders (30.5% and 31.3%, respectively). Comparisons of demographic profile and drug use patterns show that respondents who obtained equipment from personal networks were more likely to identify as gay, lesbian or bisexual (28% versus 16%, [Chi square] = 4.18, 1 d.f., p = 0.04) and live in unstable housing (22% versus 8%, [Chi square] = 8.03, 1 d.f., p < 0.01) compared to those who obtained equipment from pharmacies. The finding that respondents who obtained sterile needles and syringes from personal networks were no more likely to reuse needles and syringes may suggest that there is informal 'outreach' of primary harm reduction services through 'network nannies' or, possibly, a hidden needle syringe economy. The findings also suggest the possibility for greater harm reduction efforts in pharmacy distribution programs and in more extensively resourced peer education initiatives.
SN  - 0955-3959
AD  - National Centre in HIV Social Research, Level 2, Robert Webster Building, The University of New South Wales, Sydney, NSW 2052, Australia; j.bryant@unsw.edu.au
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105727331&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107870969
T1  - Rules and Values: A Coordinated Regulatory and Educational Approach to the Public Health Crises of Chronic Pain and Addiction.
AU  - Katzman, Joanna G.
AU  - Comerci, George D.
AU  - Landen, Michael
AU  - Loring, Larry
AU  - Jenkusky, Steven M.
AU  - Arora, Sanjeev
AU  - Kalishman, Summers
AU  - Marr, Lisa
AU  - Camarata, Chris
AU  - Duhigg, Daniel
AU  - Dillow, Jennifer
AU  - Koshkin, Eugene
AU  - Taylor, Denise E.
AU  - Geppert, Cynthia M. A.
Y1  - 2014/08//
N1  - Accession Number: 107870969. Language: English. Entry Date: 20140808. Revision Date: 20150712. Publication Type: Journal Article; pictorial; research; statistics; tables/charts. Journal Subset: Biomedical; Core Nursing; Double Blind Peer Reviewed; Nursing; Peer Reviewed; Public Health; USA. Special Interest: Pain and Pain Management; Psychiatry/Psychology; Public Health. NLM UID: 1254074. 
KW  - Chronic Pain -- Education
KW  - Substance Abuse -- Education
KW  - Substance Use Disorders -- Drug Therapy
KW  - Education, Medical, Continuing
KW  - Chronic Pain -- Drug Therapy
KW  - Public Health
KW  - Drugs, Prescription
KW  - Overdose -- Mortality
KW  - Narcotics -- Adverse Effects
KW  - New Mexico
KW  - Legislation
KW  - Government Agencies
KW  - Health Knowledge
KW  - Physician Attitudes
KW  - Self-Efficacy
KW  - Surveys
KW  - Government Regulations
KW  - Drug Utilization
KW  - Prescribing Patterns
KW  - Antianxiety Agents, Benzodiazepine
KW  - Narcotics
KW  - Coalition
KW  - Human
SP  - 1356
EP  - 1362 7p
JO  - American Journal of Public Health
JF  - American Journal of Public Health
JA  - AM J PUBLIC HEALTH
VL  - 104
IS  - 8
CY  - Washington, District of Columbia
PB  - American Public Health Association
AB  - Chronic pain and opioid addiction are 2 pressing public health problems, and prescribing clinicians often lack the skills necessary to manage these conditions. Our study sought to address the benefits of a coalition of an academic medical center pain faculty and government agencies in addressing the high unintentional overdose death rates in New Mexico. New Mexico's 2012-2013 mandated chronic pain and addiction education programs studied more than 1000 clinicians. Positive changes were noted in precourse and post-course surveys of knowledge, self-efficacy, and attitudes. Controlled substance dispensing data from the New Mexico Board of Pharmacy also demonstrated safer prescribing. The total morphine and Valium milligram equivalents dispensed have decreased continually since 2011. There was also a concomitant decline in total drug overdose deaths.
SN  - 0090-0036
AD  - Taylor are with the University of New Mexico (UNM) Health Sciences Center, Albuquerque
AD  - New Mexico Department of Health, Santa Fe
AD  - New Mexico Board of Pharmacy, Albuquerque
AD  - New Mexico Medical Board, Santa Fe
U2  - PMID: 24922121.
DO  - 10.2105/AJPH.2014.301881
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107870969&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105381917
T1  - Rx for a party: a qualitative analysis of recreational pharmaceutical use in a collegiate setting.
AU  - Quintero G
Y1  - 2009/07//Jul/Aug2009
N1  - Accession Number: 105381917. Language: English. Entry Date: 20090821. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 7503059. 
KW  - Drugs, Prescription
KW  - Recreation
KW  - Social Behavior
KW  - Students, College
KW  - Substance Abuse
KW  - Adult
KW  - Analgesics, Opioid
KW  - Antianxiety Agents
KW  - Antidepressive Agents
KW  - Central Nervous System Stimulants
KW  - Descriptive Statistics
KW  - Drug Combinations
KW  - Exploratory Research
KW  - Female
KW  - Male
KW  - Peer Group
KW  - Qualitative Studies
KW  - Semi-Structured Interview
KW  - Snowball Sample
KW  - Thematic Analysis
KW  - Human
SP  - 64
EP  - 72 9p
JO  - Journal of American College Health
JF  - Journal of American College Health
JA  - J AM COLL HEALTH
VL  - 58
IS  - 1
PB  - Taylor & Francis Ltd
AB  - Objective: Using a qualitative methodology, the author examined the sociorecreational use of pharmaceuticals in a collegiate setting. Participants: In all, 91 college students from a public, 4-year institution for higher learning in the Southwest participated in this study. Methods: The author conducted semistructured interviews between May 2004 and December 2005; they then audio recorded, transcribed, and examined the interviews for themes related to the sociorecreational use of prescription drugs. Results: A variety of prescription drugs are used for a number of purposes, including to experience pleasure, manage the duration or intensity of another drug's effects, party or socialize with friends and peers in leisure settings, facilitate sociorecreational activities, and help structure free time. Conclusions: Pharmaceuticals appear to be well integrated into the recreational drug use practices of college students, and prescription drug misuse presents a significant prevention challenge.
SN  - 0744-8481
AD  - Department of Anthropology, University of Montana, Missoula.
U2  - PMID: 19592355.
DO  - 10.3200/JACH.58.1.64-72
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105381917&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 114187676
T1  - SafeMed: Using pharmacy technicians in a novel role as community health workers to improve transitions of care.
AU  - Bailey, James E.
AU  - Surbhi, Satya
AU  - Bell, Paula C.
AU  - Jones, Angel M.
AU  - Rashed, Sahar
AU  - Ugwueke, Michael O.
Y1  - 2016/01//
N1  - Accession Number: 114187676. Language: English. Entry Date: In Process. Revision Date: 20160411. Publication Type: Article. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 101176252. 
SP  - 73
EP  - 81 9p
JO  - Journal of the American Pharmacists Association: JAPhA
JF  - Journal of the American Pharmacists Association: JAPhA
JA  - J AM PHARM ASSOC
VL  - 56
IS  - 1
CY  - Washington, District of Columbia
PB  - American Pharmacists Association
AB  - Objectives: To describe the design, implementation, and early experience of the SafeMed program, which uses certified pharmacy technicians in a novel expanded role as community health workers (CPhT-CHWs) to improve transitions of care.Setting: A large nonprofit health care system serving the major medically underserved areas and geographic hotspots for readmissions in Memphis, TN.Practice Innovation: The SafeMed program is a care transitions program with an emphasis on medication management designed to use low-cost health workers to improve transitions of care from hospital to home for superutilizing patients with multiple chronic conditions and polypharmacy.Evaluation: CPhT-CHWs were given primary responsibility for patient outreach after hospital discharge with the use of home visits and telephone follow-up. SafeMed program CPhT-CHWs served as pharmacist extenders, obtaining medication histories, assisting in medication reconciliation and identification of potential drug therapy problems (DTPs), and reinforcing medication education previously provided by the pharmacist per protocol.Results: CPhT-CHW training included patient communication skills, motivational interviewing, medication history taking, teach-back techniques, drug disposal practices, and basic disease management. Some CPhT-CHWs experienced difficulties adjusting to an expanded scope of practice. Nonetheless, once the Tennessee Board of Pharmacy affirmed that envisioned SafeMed CPhT-CHW roles were consistent with Board rules, additional responsibilities were added for CPhT-CHWs to enhance their effectiveness. Patient outreach teams including CPhT-CHWs achieved increases in home visit and telephone follow-up rates and were successful in helping identify potential DTPs.Conclusion: The early experience of the SafeMed program demonstrates that CPhT-CHWs are well suited for novel expanded roles to improve care transitions for superutilizing populations. CPhT-CHWs can identify and report potential DTPs to the pharmacist to help target medication therapy management. Critical success factors include strong CPhT-CHW patient-centered communication skills and strong pharmacist champions. In collaboration with state pharmacy boards and pharmacist associations, the SafeMed CPhT-CHW model can be successfully scaled to serve superutilizing patients throughout the country.
SN  - 1544-3191
AD  - Professor, Departments of Medicine and Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN
AD  - Graduate Research Assistant, Institute for Health Outcomes and Policy, University of Tennessee Health Science Center, Memphis, TN
AD  - SafeMed Supervisor and Clinical Pharmacy Specialist, Methodist le Bonheur Healthcare, Memphis, TN
AD  - Clinical Pharmacy Specialist, Methodist le Bonheur Healthcare, Memphis, TN
AD  - Associate Professor, Department of Clinical Pharmacy, University of Tennessee Health Science Center, Memphis, TN
AD  - President and Chief Operating Officer, Methodist le Bonheur Healthcare, Memphis, TN
U2  - PMID: 26802925.
DO  - 10.1016/j.japh.2015.11.011
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=114187676&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106398246
T1  - Samples: to use or not to use?
AU  - Daugherty KK
Y1  - 2005/12//
N1  - Accession Number: 106398246. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article; editorial. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 8704308. 
KW  - Advertising
KW  - Ethics, Medical
KW  - Pharmaceutical Companies
KW  - United States
SP  - 505
EP  - 510 6p
JO  - Journal of Clinical Pharmacy & Therapeutics
JF  - Journal of Clinical Pharmacy & Therapeutics
JA  - J CLIN PHARM THER
VL  - 30
IS  - 6
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - The United States Prescription Drug Marketing Act makes people think that samples are simply advertisement for the drug companies. However, this is not the only reason that they are used. Samples make up a large part of most drug companies' budgets and are used by many clinics with very little control. We need to ensure that these products are being used appropriately. This is becoming a big issue as reports suggest that over 90% of family practise residency clinics allow personal use of drug samples and 60% of pharmaceutical representatives have either used samples for themselves or have given them to non-physicians. The other disturbing fact is that despite the high use of samples, fewer than 10% of family practise residencies in a Brotzman and Mark study reported having written policies regarding the use of samples. The purpose of this article was to review the literature concerning the reasons for use of drug samples, and the problems associated with such use, and then to discuss possible procedures that offices, especially those that train resident physicians, can implement to ensure good governance, if such use is permitted.
SN  - 0269-4727
U2  - PMID: 16336281.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106398246&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104536093
T1  - Separate and combined effects of the GABA reuptake inhibitor tiagabine and [Delta](9)-THC in humans discriminating [Delta](9)-THC.
AU  - Lile JA
AU  - Kelly TH
AU  - Hays LR
Y1  - 2012/04//
N1  - Accession Number: 104536093. Language: English. Entry Date: 20120803. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology. NLM UID: 7513587. 
KW  - Acids -- Pharmacodynamics
KW  - Hydrocarbons -- Pharmacodynamics
KW  - Neurotransmitter Uptake Inhibitors -- Pharmacodynamics
KW  - Adolescence
KW  - Adult
KW  - Female
KW  - Heart Rate -- Drug Effects
KW  - Human
KW  - Male
KW  - Psychomotor Performance -- Drug Effects
KW  - Questionnaires
SP  - 61
EP  - 69 9p
JO  - Drug & Alcohol Dependence
JF  - Drug & Alcohol Dependence
JA  - DRUG ALCOHOL DEPENDENCE
VL  - 122
IS  - 1/2
PB  - Elsevier Science
AB  - BACKGROUND: The involvement of non-cannabinoid neurotransmitter systems in the abuse-related behavioral effects of cannabis has not been well characterized in humans. GABAergic drugs have overlapping effects with cannabis and [Delta](9)-tetrahydrocannabinol ([Delta](9)-THC) on certain behavioral measures, but those measures lack the specificity to draw conclusions regarding the involvement of GABA in cannabinoid effects. The aim of this study was to assess the separate and combined effects of the GABA reuptake inhibitor tiagabine and [Delta](9)-THC using more pharmacologically specific drug-discrimination procedures. METHODS: Eight cannabis users learned to discriminate 30mg oral [Delta](9)-THC from placebo and then received tiagabine (6 and 12mg), [Delta](9)-THC (5, 15 and 30mg) and placebo, alone and in combination. Self-report, task performance and physiological measures were also collected. RESULTS: [Delta](9)-THC produced subjective effects typically associated with cannabinoids (e.g., High, Stoned, Like Drug), elevated heart rate and impaired rate and accuracy on psychomotor performance tasks. The higher tiagabine dose substituted for the [Delta](9)-THC discriminative stimulus and engendered subjective and performance-impairing effects that overlapped with those of [Delta](9)-THC when administered alone. In combination, tiagabine shifted the discriminative-stimulus effects of [Delta](9)-THC leftward/upward and enhanced [Delta](9)-THC effects on other outcomes. CONCLUSIONS: These results indicate that GABA is involved in the clinical effects of [Delta](9)-THC, and by extension, cannabis. Future studies should test selective GABAergic compounds to determine which receptor subtype(s) are responsible for the effects observed when combined with cannabinoids.
SN  - 0376-8716
AD  - Department of Behavioral Science, University of Kentucky College of Medicine, United States.
U2  - PMID: 21975195.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104536093&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104375823
T1  - Separate and combined effects of the GABA(B) agonist baclofen and [Delta](9)-THC in humans discriminating [Delta](9)-THC.
AU  - Lile JA
AU  - Kelly TH
AU  - Hays LR
Y1  - 2012/11//
N1  - Accession Number: 104375823. Language: English. Entry Date: 20130419. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology. NLM UID: 7513587. 
KW  - Baclofen -- Pharmacodynamics
KW  - Discrimination
KW  - GABA Agonists -- Therapeutic Use
KW  - Hallucinogens -- Pharmacodynamics
KW  - Receptors, Cell Surface -- Drug Effects
KW  - Hydrocarbons -- Pharmacodynamics
KW  - Adolescence
KW  - Adult
KW  - Blood Pressure -- Drug Effects
KW  - Body Temperature -- Drug Effects
KW  - Body Temperature Regulation -- Drug Effects
KW  - Demography
KW  - Drug Interactions
KW  - Female
KW  - Heart Rate -- Drug Effects
KW  - Human
KW  - Male
KW  - Substance Use Disorders -- Psychosocial Factors
KW  - Psychomotor Performance -- Drug Effects
KW  - Questionnaires
KW  - Socioeconomic Factors
KW  - Perception -- Drug Effects
KW  - Young Adult
SP  - 216
EP  - 223 8p
JO  - Drug & Alcohol Dependence
JF  - Drug & Alcohol Dependence
JA  - DRUG ALCOHOL DEPENDENCE
VL  - 126
IS  - 1/2
PB  - Elsevier Science
AB  - BACKGROUND: Our previous research with the GABA reuptake inhibitor tiagabine suggested the involvement GABA in the interoceptive effects of [Delta](9)-THC. The aim of the present study was to determine the potential involvement of the GABA(B) receptor subtype by assessing the separate and combined effects of the GABA(B)-selective agonist baclofen and [Delta](9)-THC using pharmacologically specific drug-discrimination procedures. METHODS: Eight cannabis users learned to discriminate 30mg oral [Delta](9)-THC from placebo and then received baclofen (25 and 50mg), [Delta](9)-THC (5, 15 and 30mg) and placebo, alone and in combination. Self-report, task performance and physiological measures were also collected. RESULTS: [Delta](9)-THC functioned as a discriminative stimulus, produced subjective effects typically associated with cannabinoids (e.g., High, Stoned, Like Drug), elevated heart rate and impaired rate and accuracy on a psychomotor performance task. Baclofen alone (50mg) substituted for the [Delta](9)-THC discriminative stimulus, and both baclofen doses shifted the discriminative-stimulus effects of [Delta](9)-THC leftward/upward. Similar results were observed on other cannabinoid-sensitive outcomes, although baclofen generally did not engender [Delta](9)-THC-like subjective responses when administered alone. CONCLUSIONS: These results suggest that the GABA(B) receptor subtype is involved in the abuse-related effects of [Delta](9)-THC, and that GABA(B) receptors were responsible, at least in part, for the effects of tiagabine-induced elevated GABA on cannabinoid-related behaviors in our previous study. Future research should test GABAergic compounds selective for other GABA receptor subtypes (i.e., GABA(A)) to determine the contribution of the different GABA receptors in the effects of [Delta](9)-THC, and by extension cannabis, in humans.
SN  - 0376-8716
AD  - Department of Behavioral Science, University of Kentucky, College of Medicine, Medical Behavioral Sciences Building, Lexington, KY 40536-0086, United States. Electronic address: jalile2@email.uky.edu.
U2  - PMID: 22699093.
DO  - 10.1016/j.drugalcdep.2012.05.023
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107778502
T1  - Sex Differences in Mental Health and Substance Use Disorders and Treatment Entry Among Justice-involved Veterans in the Veterans Health Administration.
AU  - Finlay, Andrea K
AU  - Binswanger, Ingrid A
AU  - Smelson, David
AU  - Sawh, Leon
AU  - McGuire, Jim
AU  - Rosenthal, Joel
AU  - Blue-Howells, Jessica
AU  - Timko, Christine
AU  - Blodgett, Janet C
AU  - Harris, Alex H S
AU  - Asch, Steven M
AU  - Frayne, Susan
Y1  - 2015/04/02/2015 Apr Suppl 1
N1  - Accession Number: 107778502. Language: English. Entry Date: 20150529. Revision Date: 20150712. Publication Type: Journal Article; research. Supplement Title: 2015 Apr Suppl 1. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0230027. 
KW  - Mental Disorders -- Epidemiology
KW  - Prisoners
KW  - Substance Use Disorders -- Epidemiology
KW  - United States Department of Veterans Affairs
KW  - Veterans
KW  - Women's Health
KW  - Adult
KW  - Female
KW  - Human
KW  - Male
KW  - Middle Age
KW  - Prevalence
KW  - Retrospective Design
KW  - Risk Factors
KW  - Sex Factors
KW  - United States
SP  - S105
EP  - 11 1p
JO  - Medical Care
JF  - Medical Care
JA  - MED CARE
VL  - 53
IS  - 4
CY  - Baltimore, Maryland
PB  - Lippincott Williams & Wilkins
AB  - BACKGROUND: Over half of veterans in the criminal justice system have mental health or substance use disorders. However, there is a critical lack of information about female veterans in the criminal justice system and how diagnosis prevalence and treatment entry differ by sex. OBJECTIVES: To document prevalence of mental health and substance use disorder diagnoses and treatment entry rates among female veterans compared with male veterans in the justice system. RESEARCH DESIGN: Retrospective cohort study using national Veterans Health Administration clinical/administrative data from veterans seen by Veterans Justice Outreach Specialists in fiscal years 2010-2012. SUBJECTS: A total of 1535 females and 30,478 male veterans were included. MEASURES: Demographic characteristics (eg, sex, age, residence, homeless status), mental health disorders (eg, depression, post-traumatic stress disorder), substance use disorders (eg, alcohol and opioid use disorders), and treatment entry (eg, outpatient, residential, pharmacotherapy). RESULTS: Among female veterans, prevalence of mental health and substance use disorders was 88% and 58%, respectively, compared with 76% and 72% among male veterans. Women had higher odds of being diagnosed with a mental health disorder [adjusted odds ratio (AOR)=1.98; 95% confidence interval (CI), 1.68-2.34] and lower odds of being diagnosed with a substance use disorder (AOR=0.50; 95% CI, 0.45-0.56) compared with men. Women had lower odds of entering mental health residential treatment (AOR=0.69; 95% CI, 0.57-0.83). CONCLUSIONS: Female veterans involved in the justice system have a high burden of mental health disorders (88%) and more than half have substance use disorders (58%). Entry to mental health residential treatment for women is an important quality improvement target.
SN  - 0025-7079
AD  - *Center for Innovation to Implementation (Ci2i), Substance Use Disorder Quality Research Enhancement Initiative, VA Palo Alto Health Care System, Menlo Park, CA tDivision of General Internal Medicine University of Colorado School of Medicine, Community Health Services, Denver Health Medical Center, Denver, CO tNational Center on Homelessness Among Veterans, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA §Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA School of Criminology and Justice Studies, University of Massachusetts, Lowell, Bedford, MA ¶Department of Veterans Affairs, Veterans Justice Programs #Center for Innovation to Implementation (Ci2i), VA Palo Alto Health Care System, Menlo Park, CA **Department of Psychiatry and Behavioral Sciences ttDivision of General Medical Disciplines, Stanford University School of Medicine, Menlo Park, CA.
U2  - PMID: 25767963.
DO  - 10.1097/MLR.0000000000000271
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105572706
T1  - Six-month multicomponent intervention improves postnatal depression in low-income settings.
AU  - Zayas LH
Y1  - 2008/08//
N1  - Accession Number: 105572706. Language: English. Entry Date: 20090102. Revision Date: 20150711. Publication Type: Journal Article; abstract; commentary. Original Study: Rojas G, Fritsch R, Solis J, et al. Treatment of postnatal depression in low-income mothers in primary-care clinics in Santiago, Chile: a randomised controlled trial. LANCET 2007; 370: 1629-37. Journal Subset: Biomedical; Europe; UK & Ireland. Special Interest: Evidence-Based Practice; Psychiatry/Psychology. NLM UID: 100883413. 
KW  - Antidepressive Agents -- Therapeutic Use
KW  - Depression, Postpartum -- Therapy
KW  - Psychoeducation
KW  - Treatment Outcomes
KW  - Single-Blind Studies
SP  - 80
EP  - 80 1p
JO  - Evidence Based Mental Health
JF  - Evidence Based Mental Health
JA  - EVID BASED MENT HEALTH
VL  - 11
IS  - 3
PB  - BMJ Publishing Group
AB  - Question: What is the optimum way to improve treatment and recognition of postnatal depression in low-income settings? Patients: 230 women who had given birth in the previous year, and who had unrecognised and untreated postnatal depression. 922 women were initially approached while they were waiting for health-related consultations and screened for depression using the Edinburgh postnatal depression scale (EPDS; maximum score 30, higher scores indicate more severe symptoms) on two separate occasions two weeks apart. Those with persistent depression (EPDS score >=10 on both occasions) were formally assessed and those with a clinical diagnosis of major depression (DSM-IV criteria assessed through Mini International Neuropsychiatry Interview) were included in the study. Exclusions: receiving treatment for depression, pregnancy, psychotic symptoms, suicide risk, or history of mania, alcohol or drug abuse. Setting: Three clinics in deprived urban areas of Santiago, Chile; recruitment 1 June 2004 to 31 August 2005. Intervention: Multicomponent intervention or usual care. The intervention included psychoeducational groups (weekly 50 minute sessions for 8 weeks), support for treatment adherence from a trained mental health worker, and antidepressants if needed. Doctors for women in the intervention group received 5 hours of training about using a structured antidepressant protocol, and an hour of supervision from a research psychiatrist each week. Women prescribed antidepressants were given fluoxetine (20-40 mg daily), or sertraline (50-100 mg daily) if they did not respond to fluoxetine or were breastfeeding. Usual care was the service usually available in the clinic and included antidepressants, medical consultations, psychotherapy and referral for specialist treatment as required. Outcomes: Depressive symptoms (EPDS score). Patient follow-up: 90%. METHODS Design: Randomised controlled trial. Allocation: Concealed. Blinding: Single-blind (assessor blinded). Follow-up period: Six months. MAIN RESULTS The multicomponent intervention reduced symptoms of depression compared with usual care at 3 months (mean EPDS score: 8.5 with intervention vs 12.8 with usual care; adjusted mean difference: -4.5, 95% CI -6.3 to -2.7; p<0.0001; result adjusted for baseline EPDS score). By 6 months the difference was reduced but the group x time interaction overall was significant (mean EPDS score: 10.9 with intervention vs 12.5 with usual care; overall adjusted mean difference: -2.3, 95% CI -0.8 to -3.8; p = 0.002). The proportion of women taking antidepressants decreased more in the intervention group than with usual care (decrease from 59% at 3 months to 36% at 6 months in the intervention group vs 17% at 3 months to 11% at 6 months in the usual care group). Similarly, medical consultations became less common in the intervention group (mean number of consultations: 1.2 in first 3 months and 0.2 in months 3DS6 in intervention group vs 0.5 in first 3 months and 0.4 in months 3-6 in usual care group). CONCLUSIONS A multicomponent intervention that includes psycho-education, support to encourage treatment adherence and pharmacotherapy as needed is effective for women with postnatal depression in low-income settings over six months. ABSTRACTED FROM Rojas G, Fritsch R, Solis J, et al. Treatment of postnatal depression in low-income mothers in primary-care clinics in Santiago, Chile: a randomised controlled trial. Lancet 2007;370:1629-37.
SN  - 1362-0347
AD  - Washington University in St Louis, St Louis, Missouri, USA.
U2  - PMID: 18669682.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105356422
T1  - Sleep in adolescence: a review of issues for nursing practice.
AU  - Vallido T
AU  - Peters K
AU  - O'Brien L
AU  - Jackson D
Y1  - 2009/07//
N1  - Accession Number: 105356422. Language: English. Entry Date: 20090918. Revision Date: 20150819. Publication Type: Journal Article; research; systematic review. Journal Subset: Core Nursing; Europe; Nursing; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice; Pediatric Care. NLM UID: 9207302. 
KW  - Sleep Disorders -- In Adolescence
KW  - Sleep -- In Adolescence
KW  - Academic Performance
KW  - Adolescence
KW  - CINAHL Database
KW  - Computerized Literature Searching
KW  - Medline
KW  - Mental Disorders
KW  - Nursing Practice
KW  - Psycinfo
KW  - PubMed
KW  - Reference Databases, Health
KW  - Sleep -- Physiology
KW  - Substance Abuse
KW  - Systematic Review
KW  - Human
SP  - 1819
EP  - 1826 8p
JO  - Journal of Clinical Nursing
JF  - Journal of Clinical Nursing
JA  - J CLIN NURS
VL  - 18
IS  - 13
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Aims and objectives. The aim of this review was to explore the literature to determine what is known about adolescent sleep, the causes and consequences of disturbed sleep in adolescence and the implications this has for nursing practice. Background. Sleep disorders are relatively common in young people. Disturbed sleep can be both a cause and a result of ill health and if recognised can indicate psychosocial, psychological or physical difficulties. Design. Literature review. Methods. Searching of key electronic databases. Results. Disturbed sleep in adolescents has several potential consequences, including daytime sleepiness, reduced academic performance and substance use/abuse. However, despite its significance and frequency, sleep disturbance is an area of adolescent health that is almost entirely unaddressed within the nursing literature. Conclusion. Nursing has a role to play in assisting adolescents and their families to recognise the importance of sleep to the general health and well-being of young people. Relevance to clinical practice. There is a need for nursing to develop tools to assess sleep in adolescent clients and non-pharmaceutical interventions to assist adolescents achieve optimum sleep and rest. Nurses may also contribute to educating adolescents and their families regarding the importance of good sleep hygiene.
SN  - 0962-1067
U2  - PMID: 19638045.
DO  - 10.1111/j.1365-2702.2009.02812.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107491432
T1  - Smoking, cessation and the diabetes health care team.
AU  - Haire-Joshu D
Y1  - 1992/06//1992 Jun
N1  - Accession Number: 107491432. Language: English. Entry Date: 19921001. Revision Date: 20150712. Publication Type: Journal Article; questionnaire/scale; review. Journal Subset: Biomedical; Canada; Peer Reviewed. NLM UID: 9426094. 
KW  - Smoking
KW  - Smoking Cessation
KW  - Diabetes Mellitus -- Education
KW  - Nicotine -- Adverse Effects
KW  - Multidisciplinary Care Team
KW  - Substance Withdrawal Syndrome
SP  - 43
EP  - 53 11p
JO  - Beta Release
JF  - Beta Release
JA  - BETA RELEASE
VL  - 16
IS  - 2
PB  - Canadian Diabetes Association
AB  - Cigarette smoking is a major risk factor in diabetes and contributes to the development of microvascular and macrovascular complications. Despite this, approximately one third of patients with diabetes smoke. Nicotine is physically and psychologically addictive, with multiple factors contributing to the initiation and continuation of the habit. Cessation is a process in which the smoker progresses through several stages of change, including precontemplation, contemplation, action, maintenance, and relapse. Knowledge of this process is needed for the diabetes health care team to effectively individualize smoking prevention and cessation strategies. This stepped care approach includes preventive, behavioral, and pharmacologic strategies as a component of routine diabetes education.
SN  - 0710-0248
AD  - Ctr Health Behavior Research, Washington Univ School Med, St Louis, MO
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106706901
T1  - Some lifestyle habits of female Belgrade University students with migraine and non-migraine primary headache.
AU  - Vlajinac H
AU  - Sipetic S
AU  - Dzoljic E
AU  - Maksimovic J
AU  - Marinkovic J
AU  - Kostic V
Y1  - 2003/08//
N1  - Accession Number: 106706901. Language: English. Entry Date: 20040227. Revision Date: 20150711. Publication Type: Journal Article; questionnaire/scale; research; tables/charts. Journal Subset: Biomedical; Continental Europe; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Instrumentation: Questionnaire for Migraine and Headache. Grant Information: Ministry of Science, Technology and Development of Serbia through contract no. 8774 (1996-2000). NLM UID: 100940562. 
KW  - Headache -- Etiology
KW  - Life Style
KW  - Migraine -- Epidemiology -- Yugoslavia
KW  - Migraine -- Etiology
KW  - Adolescence
KW  - Adult
KW  - Chi Square Test
KW  - Confidence Intervals
KW  - Epidemiological Research
KW  - Female
KW  - Food Habits
KW  - Funding Source
KW  - Logistic Regression
KW  - Menstrual Cycle
KW  - Odds Ratio
KW  - Premenstrual Syndrome
KW  - Prevalence
KW  - Questionnaires
KW  - Sleep Deprivation
KW  - Smoking -- Complications
KW  - Statistical Significance
KW  - Students, College
KW  - Yugoslavia
KW  - Human
SP  - 67
EP  - 71 5p
JO  - Journal of Headache & Pain
JF  - Journal of Headache & Pain
JA  - J HEADACHE PAIN
VL  - 4
IS  - 2
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
AB  - We performed a prevalence study to compare some lifestyle habits between subjects with migraine and those with nonmigraine primary headaches. We surveyed female students in randomly selected classes of the School of Medicine and the School of Pharmacy, Belgrade University. Among all observed students (1943 subjects), 245 had migraine and 1053 had non-migraine primary headache. According to multivariate logistic regression analysis, the following factors were associated with migraine: irregular eating (odds ratio (OR)=1.99; 95% confidence interval (95% CI), 1.69 to 2.34; p<0.01), sleep duration shorter than usual (OR=1.18; 95% CI 1.00 to 1.38; p=0.0449) and smoking >10 cigarettes per day (OR=1.18; 95% CI=1.00 to 1.39; p=0.0433). The results of the present study are in line with some other investigations suggesting that some lifestyle habits probably play a role as migraine precipitants.
SN  - 1129-2369
AD  - Institute of Epidemiology, School of Medicine, Belgrade University, Visegradska 26, 11000 Belgrade, Yugoslavia
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104689274
T1  - Strategies to Prevent Opioid Misuse, Abuse, and Diversion That May Also Reduce the Associated Costs.
AU  - Hahn, Kathryn L.
Y1  - 2011/03//
N1  - Accession Number: 104689274. Language: English. Entry Date: 20110927. Revision Date: 20150819. Publication Type: Journal Article; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Health Services Administration; Peer Reviewed; USA. 
KW  - Analgesics, Opioid -- Adverse Effects
KW  - Substance Abuse -- Prevention and Control
KW  - Health Care Costs
KW  - Substance Abuse -- Risk Factors
KW  - Pain -- Drug Therapy
KW  - Analgesics, Opioid -- Therapeutic Use
KW  - Health Resource Utilization -- Economics
KW  - United States
KW  - Substance Abuse Detection
KW  - Physician-Patient Relations
KW  - Substance Abuse -- Education
KW  - Patient Education
KW  - Prescribing Patterns
KW  - Contracts
KW  - Medication Compliance
KW  - Insurance, Health
KW  - Treatment Errors -- Prevention and Control
KW  - Narcotics -- Antagonists and Inhibitors
KW  - Dosage Forms
KW  - Naltrexone -- Therapeutic Use
SP  - 107
EP  - 113 7p
JO  - American Health & Drug Benefits
JF  - American Health & Drug Benefits
JA  - AM HEALTH DRUG BENEFITS
VL  - 4
IS  - 2
CY  - Cranbury, New Jersey
PB  - Engage Healthcare Communications, LLC
AB  - Background: The use of prescription opioid drugs has the potential to lead to patient abuse of these medications, addiction, and diversion. Such an abuse is associated with increased costs because of excessive healthcare utilization. Finding ways to minimize the risk for abuse and addiction can enhance patient outcomes and reduce costs to patients and to payers. Objective: To review current strategies that may reduce the risk for misuse and abuse of opioid medications, which in turn can enhance patient outcomes and lower costs to health insurers and patients. Discussion: Implementing approaches that will encourage the use of safe practices (universal precautions) in pain management by providers can reduce the risk for abuse and misuse associated with chronic pain medications, especially opioids. These approaches include, but are not limited to, extensive physician and patient education regarding these medications and their associated risks for abuse; the development of prescription monitoring programs to detect physician or pharmacy shopping; the detection of inappropriate prescribing and medical errors; the use of physician-patient contracts concerning opioid treatment; the requirement of presenting a photo identification to pick up an opioid prescription at the pharmacy; urine drug toxicology screening; provisions for safe disposal of unused opioids; referrals to pain and addiction specialists; and potentially encouraging the use of opioid formulations aimed at reducing abuse. Conclusion: Supporting such approaches by health insurers and educating providers and patients on the risks associated with chronic pain medications can help minimize the risk of prescription opioid abuse, addiction, and diversion; reduce health services utilization associated with opioid abuse; improve patient outcomes; and reduce overall costs.
SN  - 1942-2962
AD  - Affiliate Faculty, Oregon State University College of Pharmacy; Pharmacy Manager, Bi-Mart Corp, Springfield, OR
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - THES
ID  - 109870327
T1  - Stress, alcohol, and psychoactive drug use among nurses in Massachusetts.
AU  - Valentine NM
Y1  - 1991/01//
N1  - Accession Number: 109870327. Language: English. Entry Date: 19930301. Revision Date: 20150923. Publication Type: Doctoral Dissertation; research. 
KW  - Substance Abuse -- Evaluation
KW  - Impairment, Health Professional
KW  - Stress, Psychological
KW  - Registered Nurses
KW  - Risk Factors
KW  - Comparative Studies
KW  - Descriptive Research
KW  - Substance Abuse -- Prevention and Control
KW  - Physicians
KW  - Students, Medical
KW  - Human
SP  - 948 p
EP  - 948 p 1p
JO  - Stress, Alcohol & Psychoactive Drug Use Among Nurses in Massachusetts
JF  - Stress, Alcohol & Psychoactive Drug Use Among Nurses in Massachusetts
PB  - BRANDEIS U., THE F. HELLER GRAD. SCH. FOR ADV. STUD. IN SOC. WEL.
AB  - The investigation explored alcohol and psychoactive substance use among a normal population of nurses for the purposes of having a better understanding about the patterns of psychoactive substance use and the identification of risk factors which may contribute to impairment for some nurses. Particular attention was paid to the impact stress factors may have in substance use overall. The central question addressed by this study was: What are the patterns of stress, alcohol, and psychoactive drug use by a randomly selected group of normal, registered nurses, with particular emphasis on working nurses, and can these patterns be used to identify risk factors in order to more accurately estimate the extent of the problem among all practicing nurses? Detailed analysis was conducted for all nurses and working nurses on multiple dimensions of the questionnaire. Results were determined for the following: (1) Description of the Sample; (2) Patterns of Alcohol Use and Associated Stress Factors; (3) Patterns of Psychoactive Drug Use and Associated Stress Factors; (4) Patterns of Combined Alcohol and Drug Use and Associated Stress Factors; (5) General Description of Other Populations of Interest: Male Nurses and Impaired Nurses; (6) Comparative Analysis of Nurses, Physicians, Medical Students, Pharmacists, and Pharmacy Students. Nurses reported low use of alcohol overall, high use of psychoactive drugs for therapeutic purposes, and low incidence of current alcohol dependence. Use of alcohol and drugs by those nurses who became dependent was associated with history of family problems and smoking habit. Applying the at risk formula for impairment used by McAuliffe et al. in their work with physicians and medical students, nurses in this study were found to be at much higher risk for impairment, as compared with physicians and medical students. The large difference was related to nurses' use of therapeutic drugs, particularly those utilized by prescription. In conclusion, prevalence of impairment among this group of nurses was less than expected. However, health policy and economic recommendations emphasize the need for prevention, increased awareness of the problem, and the addressing of the complex productivity issues involved in impaired nursing practice. (Abstract shortened with permission of author.)
AV  - UMI Order PUZ9129529
M1  - PH.D.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109870327&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104447178
T1  - Student and school characteristics associated with use of nicotine replacement therapy: A multilevel analysis among Canadian youth.
AU  - Lane NE
AU  - Leatherdale ST
AU  - Dubin JA
AU  - Hammond D
Y1  - 2012/07//
N1  - Accession Number: 104447178. Language: English. Entry Date: 20120921. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. Special Interest: Psychiatry/Psychology. NLM UID: 7603486. 
KW  - Nicotine -- Administration and Dosage
KW  - Nicotinic Agonists -- Administration and Dosage
KW  - Smoking -- Prevention and Control
KW  - Smoking Cessation
KW  - Industry -- Utilization
KW  - Canada
KW  - Female
KW  - Human
KW  - Male
KW  - Statistics
KW  - Questionnaires
KW  - Residence Characteristics
KW  - Rural Health
KW  - Schools
KW  - Smoking -- Epidemiology
KW  - Students
KW  - Urban Health
SP  - 811
EP  - 816 6p
JO  - Addictive Behaviors
JF  - Addictive Behaviors
JA  - ADDICT BEHAV
VL  - 37
IS  - 7
PB  - Pergamon Press - An Imprint of Elsevier Science
AB  - BACKGROUND: Research indicates that it is common for youths to use nicotine replacement therapy (NRT) despite limited empirical evidence for its effectiveness within this population. Since very little is known about the characteristics associated with NRT use by youth, the current study examined the association between ever and current use of NRT as a function of student characteristics and the characteristics of the schools they attend. METHODS: This study used nationally representative student-level data from 29,296 grade 9 to 12 students who participated in the 2008-2009 Canadian Youth Smoking Survey (YSS). School-level data on the built environment surrounding schools were provided by DMTI-Spatial, and data on school location were provided by the Canadian Census. Two multilevel logistic regression models were used to predict ever use of NRT and current use of NRT as a function of student and school characteristics among current smokers. RESULTS: Overall, 21.1% of youth smokers in Canada had ever used NRT and 5.1% were currently using NRT. Odds of ever and current NRT use were highest among daily smokers and boys, while youths who had made multiple quit attempts or participated in a quit and win contest were more likely to be ever NRT users. Attending a school located within an urban area increased youths' odds of ever and current NRT use, whereas higher density of pharmacies surrounding a school was inversely associated with current NRT use. CONCLUSIONS: Characteristics of students and the schools they attend were associated with the likelihood of youth smokers using NRT. Significant between-school differences in NRT use exist, however further research is needed to identify which school characteristics account for these differences and understand how youth are accessing NRT.
SN  - 0306-4603
AD  - School of Public Health and Health Systems, University of Waterloo, 200 University Avenue West, ON, Canada N2L 3G1.
U2  - PMID: 22475584.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104447178&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104137623
T1  - STUDY ON IMPACT OF PHARMACOLOGY TEACHING ON KNOWLEDGE, ATTITUDE AND PRACTICE ON SELF-MEDICATION AMONG MEDICAL STUDENTS.
AU  - Patel, Pragna
AU  - Prajapati, Arpit
AU  - Ganguly, Barna
AU  - Gajjar, Bharat
Y1  - 2013/06//
N1  - Accession Number: 104137623. Language: English. Entry Date: 20140121. Revision Date: 20150710. Publication Type: Journal Article; research; tables/charts. Journal Subset: Asia; Biomedical; Public Health. Special Interest: Public Health. 
KW  - Self Medication
KW  - Students, Medical
KW  - Pharmacy and Pharmacology -- Education
KW  - Student Attitudes
KW  - Health Knowledge
KW  - Health Behavior
KW  - Human
KW  - Substance Abuse
KW  - Drugs, Non-Prescription -- Adverse Effects
KW  - Male
KW  - Female
KW  - Questionnaires
KW  - Pilot Studies
KW  - India
SP  - 181
EP  - 186 6p
JO  - International Journal of Medical Science & Public Health
JF  - International Journal of Medical Science & Public Health
JA  - INT J MED SCI PUBLIC HEALTH
VL  - 2
IS  - 2
PB  - International Journal of Medical Science & Public Health
SN  - 2277-338X
AD  - Cadila Pharmaceuticals Limited, Ahmedabad, Gujarat, India
AD  - Lambda Clinical Research, Ahmedabad, Gujarat, India
AD  - Department of Pharmacology, Pramukh Swami Medical College, Karamsad, Anand, Gujarat, India
DO  - 10.5455/ijmsph.2013.2.173-178
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104807363
T1  - Substance use attitudes and behaviors at three pharmacy colleges.
AU  - Baldwin JN
AU  - Scott DM
AU  - DeSimone II EM
AU  - Forrester JH
AU  - Fankhauser MP
Y1  - 2011/01//Jan-Mar2011
N1  - Accession Number: 104807363. Language: English. Entry Date: 20110314. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 8808537. 
KW  - Students, Pharmacy -- Psychosocial Factors
KW  - Student Attitudes
KW  - Substance Abuse -- Psychosocial Factors
KW  - Alcohol Abuse -- Psychosocial Factors
KW  - Risk Taking Behavior
KW  - Southwestern United States
KW  - Midwestern United States
KW  - Data Analysis Software
KW  - Chi Square Test
KW  - Questionnaires
KW  - Human
KW  - Male
KW  - Female
KW  - Substance Abuse -- Education
KW  - Smoking
KW  - Family History -- Psychosocial Factors
KW  - Education, Pharmacy
KW  - Self Report
KW  - Adult
SP  - 27
EP  - 35 9p
JO  - Substance Abuse
JF  - Substance Abuse
JA  - SUBST ABUSE
VL  - 32
IS  - 1
PB  - Taylor & Francis Ltd
AB  - The objective of this study was to profile and compare alcohol and other drug (AOD) use attitudes and behaviors in three pharmacy colleges. Student surveys of AOD use attitudes and behaviors were conducted at one southwestern and two midwestern pharmacy colleges. Response was 86.5% (566/654). Reported past-year use included alcohol 82.8%, tobacco 25.4%, and marijuana 6.9%. Past-year AOD-associated events included blackouts 18.2%, class or work under influence 7.8%, patient care under influence 1.4%, lowered grades or job evaluations 5.8%, legal charges 2.7%, and heavy drinking 29.0%. Family histories of alcohol or drug problems were reported by 35.5% and 13.1%, respectively. A number of significant differences in AOD use attitudes and behaviors between the three colleges were identified. Pharmacy students reported a number of risky drug-use attitudes and behaviors in this survey. Student AOD prevention, assistance, and education should be proactively addressed by pharmacy colleges.
SN  - 0889-7077
AD  - College of Pharmacy, The University of Nebraska Medical Center, Omaha, Nebraska, USA
U2  - PMID: 21302181.
DO  - 10.1080/08897077.2011.540470
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106547800
T1  - Substance use by pharmacy and nursing practitioners and students in a northeastern state.
AU  - Kenna GA
AU  - Wood MD
Y1  - 2004/05//5/1/2004
N1  - Accession Number: 106547800. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Alcohol Drinking
KW  - Nurses
KW  - Pharmacists
KW  - Smoking
KW  - Students, Nursing
KW  - Students, Pharmacy
KW  - Analysis of Variance
KW  - Bivariate Statistics
KW  - Cannabis
KW  - Chi Square Test
KW  - Colleges and Universities
KW  - Convenience Sample
KW  - Correlation Coefficient
KW  - Descriptive Research
KW  - Descriptive Statistics
KW  - Female
KW  - Logistic Regression
KW  - Mail
KW  - Male
KW  - Questionnaires
KW  - Random Sample
KW  - Rhode Island
KW  - Substance Abuse -- Risk Factors
KW  - Survey Research
KW  - T-Tests
KW  - Human
SP  - 921
EP  - 930 10p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 61
IS  - 9
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
AB  - PURPOSE: The prevalence and predictors of substance use among pharmacists and nurses and pharmacy and nursing students were studied. METHODS: During summer 2002, pharmacists and nurses in a northeastern state were mailed an anonymous survey to determine their use of alcohol, tobacco, and commonly abused drugs; to determine their ease of access to controlled substances; and to measure their family history of alcohol and drug problems. A similar but not identical survey was distributed to pharmacy and nursing students during spring 2000. RESULTS: A total of 262 usable questionnaires were received from pharmacists and nurses (response rate, 72.8%), and 138 usable questionnaires were received from students (35.3%). Large majorities of nursing students, pharmacy students, and nurses were women. A higher percentage of pharmacists reported having used an opioid or an anxiolytic at least once in their lives (24.8% and 14.3%, respectively) than nurses (14.5% and 7.8%). Higher percentages of nursing students and nurses reported having ever used an unprescribed drug (74.5% of nursing students and 63.6% of nurses). CONCLUSION: A survey of pharmacy and nursing practitioners and students in a northeastern state provided important information on alcohol, tobacco, and illicit drug use among these groups and highlighted the need for prevention and intervention.
SN  - 1079-2082
AD  - Postdoctoral Fellow in Substance Abuse Treatment Research, Department of Psychiatry and Human Behavior, Brown University Medical School, Providence, RI; george_kenna@brown.edu
U2  - PMID: 15156968.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106547800&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105514891
T1  - Subtypes of nonmedical prescription drug misuse.
AU  - McCabe SE
AU  - Boyd CJ
AU  - Teter CJ
Y1  - 2009/06//
N1  - Accession Number: 105514891. Language: English. Entry Date: 20090717. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology. NLM UID: 7513587. 
KW  - Drugs, Prescription
KW  - Substance Use Disorders -- Classification
KW  - Adolescence
KW  - Adult
KW  - Alcoholism -- Epidemiology
KW  - Alcoholism -- Psychosocial Factors
KW  - Analgesics, Opioid
KW  - Antianxiety Agents
KW  - Central Nervous System Stimulants
KW  - Data Analysis, Statistical
KW  - Ethnic Groups
KW  - Female
KW  - Hypnotics and Sedatives
KW  - Logistic Regression
KW  - Male
KW  - Motivation
KW  - Self Administration
KW  - Sex Factors
KW  - Students
KW  - Substance Use Disorders -- Epidemiology
KW  - Substance Use Disorders -- Psychosocial Factors
KW  - United States
KW  - Human
SP  - 63
EP  - 70 8p
JO  - Drug & Alcohol Dependence
JF  - Drug & Alcohol Dependence
JA  - DRUG ALCOHOL DEPENDENCE
VL  - 102
IS  - 1-3
PB  - Elsevier Science
AB  - This study used three characteristics (i.e., motive, route of administration, and co-ingestion with alcohol) of nonmedical prescription drug misuse across four separate classes (i.e., pain, sedative/anxiety, sleeping, and stimulant medications) to examine subtypes and drug related problems. A Web survey was self-administered by a randomly selected sample of 3639 undergraduate students attending a large midwestern 4-year U.S. university. Self-treatment subtypes were characterized by motives consistent with the prescription drug's pharmaceutical main indication, oral only routes of administration, and no co-ingestion with alcohol. Recreational subtypes were characterized by recreational motives, oral or non-oral routes, and co-ingestion. Mixed subtypes consisted of other combinations of motives, routes, and co-ingestion. Among those who reported nonmedical prescription drug misuse, approximately 13% were classified into the recreational subtype, while 39% were in the self-treatment subtype, and 48% were in the mixed subtype. There were significant differences in the subtypes in terms of gender, race and prescription drug class. Approximately 50% of those in subtypes other than self-treatment screened positive for drug abuse. The odds of substance use and abuse were generally lower among self-treatment subtypes than other subtypes. The findings indicate subtypes should be considered when examining nonmedical prescription drug misuse, especially for pain medication.
SN  - 0376-8716
AD  - University of Michigan Substance Abuse Research Center, 2025 Traverwood Dr., Suite C, Ann Arbor, MI 48105-2194, USA; University of Michigan Institute for Research on Women and Gender, 1136 Lane Hall, Ann Arbor, MI 48109-1290, USA.
U2  - PMID: 19278795.
DO  - 10.1016/j.drugalcdep.2009.01.007
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109545145
T1  - Survey of career satisfaction, lifestyle, and stress levels among pharmacy school faculty.
AU  - LINDFELT, TRISTAN A.
AU  - IP, ERIC J.
AU  - BARNETT, MITCHELL J.
Y1  - 2015/09/15/
N1  - Accession Number: 109545145. Language: English. Entry Date: 20150922. Revision Date: 20151007. Publication Type: Article. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. Instrumentation: Perceived Stress Scale (PSS) (Cohen et al). NLM UID: 9503023. 
KW  - Education, Pharmacy
KW  - Faculty -- Psychosocial Factors -- United States
KW  - Job Satisfaction
KW  - Life Style
KW  - Stress, Psychological
KW  - Work-Life Balance
KW  - Health Behavior
KW  - Mental Disorders
KW  - Substance Abuse
KW  - Human
KW  - United States
KW  - Questionnaires
KW  - Descriptive Statistics
KW  - Female
KW  - Male
KW  - Scales
KW  - Data Analysis Software
KW  - Adult
KW  - Middle Age
KW  - Young Adult
KW  - Aged
SP  - 1573
EP  - 1578 6p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 72
IS  - 18
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
SN  - 1079-2082
AD  - Assistant Professor of Pharmacy Practice and Residency Program Director, Touro University California College of Pharmacy, Vallejo
AD  - Associate Professor of Pharmacy Practice and Department Chair, Touro University California College of Pharmacy, Vallejo
AD  - Adjunct Associate Professor of Pharmacy Practice, Touro University California College of Pharmacy, Vallejo
U2  - PMID: 26346213.
DO  - 10.2146/ajhp140654
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104645703
T1  - Task allocation in cancer medication management - Integrating the pharmacist.
AU  - Döhler N
AU  - Krolop L
AU  - Ringsdorf S
AU  - Meier K
AU  - Ko YD
AU  - Kuhn W
AU  - Schwalbe O
AU  - Jaehde U
Y1  - 2011/06//
N1  - Accession Number: 104645703. Language: English. Entry Date: 20111028. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Core Nursing; Europe; Health Promotion/Education; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 8406280. 
KW  - Counseling
KW  - Drug Therapy
KW  - Multidisciplinary Care Team -- Administration
KW  - Pharmacists
KW  - Cooperative Behavior
KW  - Female
KW  - Focus Groups
KW  - Germany
KW  - Interprofessional Relations
KW  - Male
KW  - Neoplasms -- Drug Therapy
KW  - Nurses
KW  - Patient Education
KW  - Physicians
KW  - Questionnaires
SP  - 367
EP  - 374 8p
JO  - Patient Education & Counseling
JF  - Patient Education & Counseling
JA  - PATIENT EDUC COUNS
VL  - 83
IS  - 3
PB  - Elsevier Science
AB  - OBJECTIVE: This study was conducted to define the task allocation in multiprofessional cancer medication management (MCMM) with a special focus on the role of the pharmacist as well as patient education and counseling. The acceptance of the proposed task allocation and the perceptions on multiprofessional teamwork were explored on a national level. METHODS: We held local focus group meetings (University of Bonn with collaboration partners) to identify MCMM tasks. With the Delphi technique the tasks were allocated to physicians, pharmacists and nurses. Professionals (members of the German Cancer Society) were approached nationwide via an online questionnaire to evaluate the acceptance of the MCMM model and explore their perceptions on multiprofessional teamwork. RESULTS: The MCMM model comprised 38 tasks including 11 on patient education and counseling. It was rated to be reasonable (79%) and feasible (68%). Barriers and benefits of multiprofessional teamwork stated were patient-, team-, therapy-, structure-, and resources-related. CONCLUSIONS: The MCMM model integrates the pharmacist with responsibilities in patient education and counseling as well as prevention of drug-related problems. The approach was generally appreciated nationwide by the professions. PRACTICE IMPLICATIONS: The proposed model can serve as a tool to trigger changes in cancer medication management.
SN  - 0738-3991
AD  - Department of Clinical Pharmacy, University of Bonn, Bonn, Germany.
U2  - PMID: 21482061.
DO  - 10.1016/j.pec.2011.03.002
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 112376940
T1  - Teaching Medical Students to Help Patients Quit Smoking: Outcomes of a 10-School Randomized Controlled Trial.
AU  - Ockene, Judith
AU  - Hayes, Rashelle
AU  - Churchill, Linda
AU  - Crawford, Sybil
AU  - Jolicoeur, Denise
AU  - Murray, David
AU  - Shoben, Abigail
AU  - David, Sean
AU  - Ferguson, Kristi
AU  - Huggett, Kathryn
AU  - Adams, Michael
AU  - Okuliar, Catherine
AU  - Gross, Robin
AU  - Bass, Pat
AU  - Greenberg, Ruth
AU  - Leone, Frank
AU  - Okuyemi, Kola
AU  - Rudy, David
AU  - Waugh, Jonathan
AU  - Geller, Alan
Y1  - 2016/02//
N1  - Accession Number: 112376940. Language: English. Entry Date: In Process. Revision Date: 20160210. Publication Type: journal article. Journal Subset: Biomedical; Continental Europe; Europe. NLM UID: 8605834. 
SP  - 172
EP  - 181 10p
JO  - JGIM: Journal of General Internal Medicine
JF  - JGIM: Journal of General Internal Medicine
JA  - J GEN INTERN MED
VL  - 31
IS  - 2
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
AB  - Background: Early in medical education, physicians must develop competencies needed for tobacco dependence treatment.Objective: To assess the effect of a multi-modal tobacco dependence treatment curriculum on medical students' counseling skills.Design: A group-randomized controlled trial (2010-2014) included ten U.S. medical schools that were randomized to receive either multi-modal tobacco treatment education (MME) or traditional tobacco treatment education (TE).Setting/participants: Students from the classes of 2012 and 2014 at ten medical schools participated. Students from the class of 2012 (N = 1345) completed objective structured clinical examinations (OSCEs), and 50 % (N = 660) were randomly selected for pre-intervention evaluation. A total of 72.9 % of eligible students (N = 1096) from the class of 2014 completed an OSCE and 69.7 % (N = 1047) completed pre and post surveys.Interventions: The MME included a Web-based course, a role-play classroom demonstration, and a clerkship booster session. Clerkship preceptors in MME schools participated in an academic detailing module and were encouraged to be role models for third-year students.Measurements: The primary outcome was student tobacco treatment skills using the 5As measured by an objective structured clinical examination (OSCE) scored on a 33-item behavior checklist. Secondary outcomes were student self-reported skills for performing 5As and pharmacotherapy counseling.Results: Although the difference was not statistically significant, MME students completed more tobacco counseling behaviors on the OSCE checklist (mean 8.7 [SE 0.6] vs. mean 8.0 [SE 0.6], p = 0.52) than TE students. Several of the individual Assist and Arrange items were significantly more likely to have been completed by MME students, including suggesting behavioral strategies (11.8 % vs. 4.5 %, p < 0.001) and providing information regarding quitline (21.0 % vs. 3.8 %, p < 0.001). MME students reported higher self-efficacy for Assist, Arrange, and Pharmacotherapy counseling items (ps ≤0.05).Limitations: Inclusion of only ten schools limits generalizability.Conclusions: Subsequent interventions should incorporate lessons learned from this first randomized controlled trial of a multi-modal longitudinal tobacco treatment curriculum in multiple U.S. medical schools. NIH Trial Registry Number: NCT01905618.
SN  - 0884-8734
AD  - Division of Preventive and Behavioral Medicine, Department of Medicine, University of Massachusetts Medical School, 55 Lake Avenue North Worcester 01655 USA
AD  - Biostatistics and Bioinformatics Branch; Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda USA
AD  - Division of Biostatistics, College of Public Health, The Ohio State University, Columbus USA
AD  - Center for Education & Research in Family and Community Medicine, Division of General Medical Disciplines, Department of Medicine, Stanford University School of Medicine, Palo Alto USA
AD  - University of Iowa Carver College of Medicine, Iowa City USA
AD  - Department of Medicine, Creighton University School of Medicine, Omaha USA
AD  - Department of Medicine, Georgetown University Hospital, Washington USA
AD  - Louisiana State University Health Shreveport, Shreveport USA
AD  - University of Louisville School of Medicine, Louisville USA
AD  - Division of Pulmonary, Allergy and Critical Care Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia USA
AD  - Department of Family and Community Health, University of Minnesota School of Medicine, Minneapolis USA
AD  - University of Kentucky College of Medicine, Lexington USA
AD  - Clinical and Diagnostics Sciences Department, School of Health Professions, UAB Lung Health Center, University of Alabama at Birmingham, Birmingham USA
AD  - Department of Social and Behavioral Sciences, Harvard School of Public Health, Boston USA
U2  - PMID: 26391030.
DO  - 10.1007/s11606-015-3508-y
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=112376940&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 112828664
T1  - Text mining for pharmacovigilance: Using machine learning for drug name recognition and drug-drug interaction extraction and classification.
AU  - Ben Abacha, Asma
AU  - Chowdhury, Md. Faisal Mahbub
AU  - Karanasiou, Aikaterini
AU  - Mrabet, Yassine
AU  - Lavelli, Alberto
AU  - Zweigenbaum, Pierre
Y1  - 2015/12//
N1  - Accession Number: 112828664. Language: English. Entry Date: In Process. Revision Date: 20160409. Publication Type: journal article. Journal Subset: Biomedical; Computer/Information Science; Peer Reviewed; USA. NLM UID: 100970413. 
SP  - 122
EP  - 132 11p
JO  - Journal of Biomedical Informatics
JF  - Journal of Biomedical Informatics
JA  - J BIOMED INFORM
VL  - 58
CY  - Burlington, Massachusetts
PB  - Academic Press Inc.
AB  - Pharmacovigilance (PV) is defined by the World Health Organization as the science and activities related to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problem. An essential aspect in PV is to acquire knowledge about Drug-Drug Interactions (DDIs). The shared tasks on DDI-Extraction organized in 2011 and 2013 have pointed out the importance of this issue and provided benchmarks for: Drug Name Recognition, DDI extraction and DDI classification. In this paper, we present our text mining systems for these tasks and evaluate their results on the DDI-Extraction benchmarks. Our systems rely on machine learning techniques using both feature-based and kernel-based methods. The obtained results for drug name recognition are encouraging. For DDI-Extraction, our hybrid system combining a feature-based method and a kernel-based method was ranked second in the DDI-Extraction-2011 challenge, and our two-step system for DDI detection and classification was ranked first in the DDI-Extraction-2013 task at SemEval. We discuss our methods and results and give pointers to future work.
SN  - 1532-0464
AD  - Luxembourg Institute of Science and Technology, Luxembourg
AD  - IBM Research, NY, USA
AD  - HLT Research Unit, FBK, Trento, Italy
AD  - LIMSI-CNRS, Orsay, France
U2  - PMID: 26432353.
DO  - 10.1016/j.jbi.2015.09.015
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=112828664&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104514023
T1  - The diversion and misuse of pharmaceutical stimulants: what do we know and why should we care?
AU  - Kaye, Sharlene
AU  - Darke, Shane
Y1  - 2012/03//
N1  - Accession Number: 104514023. Language: English. Entry Date: 20120418. Revision Date: 20150711. Publication Type: Journal Article; review; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology; Public Health. NLM UID: 9304118. 
KW  - Attention Deficit Hyperactivity Disorder -- Drug Therapy
KW  - Prescriptions, Drug -- Trends
KW  - Self Medication -- Trends
KW  - Methylphenidate -- Pharmacodynamics
KW  - Amphetamine -- Pharmacodynamics
KW  - Substance Abuse -- Psychosocial Factors
KW  - Medline
KW  - Embase
KW  - PubMed
KW  - Adolescence
KW  - Young Adult
KW  - Risk Factors
KW  - Adverse Drug Event
KW  - Student Attitudes
KW  - Prescribing Patterns
SP  - 467
EP  - 477 11p
JO  - Addiction
JF  - Addiction
JA  - ADDICTION
VL  - 107
IS  - 3
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - ABSTRACT Aims To examine the literature pertaining to the diversion and misuse of pharmaceutical stimulants. Methods Relevant literature was identified through comprehensive MEDLINE, EMBASE and PubMed searches. Results The evidence to date suggests that the prevalence of diversion and misuse of pharmaceutical stimulants varies across adolescent and young adult student populations, but is higher than that among the general population, with the highest prevalence found among adults with attention deficit-hyperactive disorder (ADHD) and users of other illicit drugs. Concerns that these practices have become more prevalent as a result of increased prescribing are not supported by large-scale population surveys. Information on trends in misuse in countries where there have been recent increases in prescription and consumption rates, however, is limited. Little is known about the frequency and chronicity of misuse, or the extent of associated harms, particularly among those populations, i.e. adolescents, young adult student populations, those with ADHD and illicit drug users, where abuse may be more likely to occur. Conclusions Continued monitoring of the diversion and misuse of pharmaceutical stimulants is of major clinical importance. Despite recognition of the abuse liability of these medications, there is a paucity of data on the prevalence, patterns and harms of diversion and misuse among populations where problematic use and abuse may be most likely to occur (e.g. adolescents, young adults, illicit drug users). Comprehensive investigations of diversion and misuse among these populations should be a major research priority, as should the assessment of abuse and dependence criteria among those identified as regular users.
SN  - 0965-2140
AD  - National Drug and Alcohol Research Centre, University of New South Wales, NSW, Australia
U2  - PMID: 22313101.
DO  - 10.1111/j.1360-0443.2011.03720.x
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104514023&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106793243
T1  - The general public's perceptions and use of antimicrobials in Trinidad and Tobago.
AU  - Parimi N
AU  - Pinto Pereira LM
AU  - Prabhakar P
Y1  - 2002/07//2002 Jul
N1  - Accession Number: 106793243. Language: English. Entry Date: 20030103. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; Public Health; USA. NLM UID: 9705400. 
KW  - Caregivers -- Psychosocial Factors
KW  - Health Knowledge
KW  - Oral Rehydration Therapy
KW  - Dehydration -- Therapy -- In Infancy and Childhood
KW  - Diarrhea -- Complications -- In Infancy and Childhood
KW  - Attitude to Health -- Ethnology
KW  - Socioeconomic Factors
KW  - Odds Ratio
KW  - Interviews
KW  - Case Control Studies
KW  - Confidence Intervals
KW  - Descriptive Statistics
KW  - Observational Methods
KW  - P-Value
KW  - One-Way Analysis of Variance
KW  - Family
KW  - Convenience Sample
KW  - Jamaica
KW  - Infant
KW  - Child, Preschool
KW  - Adult
KW  - Human
SP  - 11
EP  - 18 8p
JO  - Revista Panamericana de Salud Publica
JF  - Revista Panamericana de Salud Publica
JA  - PAN AM J PUBLIC HEALTH
VL  - 12
IS  - 1
CY  - Washington, District of Columbia
PB  - Pan American Health Organization
AB  - OBJECTIVE: To determine the general public's perceptions and use of antibiotics in Trinidad and Tobago, a two-island republic in the Caribbean. METHODS: This prospective study surveyed 824 randomly selected households listed in the telephone directory, from November 1998 to January 1999. Through telephone interviews we determined knowledge about antibiotics and beliefs concerning their safety and efficacy. We studied the influence of age, gender, education, and having private health insurance on knowledge, self-medication, storing medication at home for emergency use ('hoarding'), and asking a private doctor to prescribe antibiotics ('demand prescribing'). RESULTS: For the 824 telephone calls that the interviewers completed, 753 of the households agreed to participate (91.4% response rate). Of those 753 participants, 699 of them (93%) knew the term 'antibiotic,' 29% (206/699) said it was a drug for bacterial infections, and 25% (170/690) had asked a doctor for an antibiotic prescription. Penicillin was correctly identified as an antibiotic across age, gender, and education categories, but 36% of respondents incorrectly said Benadryl (diphenhydramine), a common over-the-counter cough and cold formulation, was an antibiotic. Gender was not significantly associated with knowledge of antibiotic safety, with self-medication, or with hoarding antibiotics. On the other hand, completion of tertiary (university) education was significantly associated with correct knowledge of the safety of antibiotics and whether or not they could cure all infections. Of the various antimicrobials, beta-lactams were the ones that survey respondents had used most frequently in the preceding year, and 20% of antibiotics users had used multiple antibiotics in that period. In comparison to persons with private health insurance, more individuals without private health insurance said that antibiotics are safe and do not have side effects, and more of them also incorrectly called aspirin and Benadryl antibiotics. CONCLUSIONS: In Trinidad and Tobago, inappropriate use of antimicrobials results from self-medication, over-the-counter availability at the community pharmacy, prescribing on demand, and lack of regulatory control. In order to contain antibiotic abuse, both the Drug Inspectorate of the Ministry of Health and the Pharmacy Board should exert stricter control on the dispensing of antibiotics at private pharmacies. Further, education of the general public and of health care professionals on antibiotic misuse and appropriate use must be instituted, along with community-based surveillance of antimicrobial resistance trends.
SN  - 1020-4989
AD  - Bishop Anstey High School, Port-of-Spain, Trinidad and Tobago
U2  - PMID: 12202020.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106793243&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105894474
T1  - The implementation of buprenorphine/naloxone in college health practice.
AU  - DeMaria PA Jr.
AU  - Patkar AA
Y1  - 2008/01//Jan/Feb2008
N1  - Accession Number: 105894474. Language: English. Entry Date: 20080418. Revision Date: 20150711. Publication Type: Journal Article; case study. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 7503059. 
KW  - Buprenorphine -- Pharmacodynamics
KW  - Buprenorphine -- Therapeutic Use
KW  - Naloxone -- Pharmacodynamics
KW  - Naloxone -- Therapeutic Use
KW  - Student Health Services -- Administration
KW  - Substance Use Disorders -- Drug Therapy
KW  - Adult
KW  - Drug Combinations
KW  - Male
SP  - 391
EP  - 393 3p
JO  - Journal of American College Health
JF  - Journal of American College Health
JA  - J AM COLL HEALTH
VL  - 56
IS  - 4
PB  - Taylor & Francis Ltd
AB  - Opiate abuse and dependence have become important concerns for college healthcare providers. The passage of the Drug Addiction Treatment Act of 2000 and the approval of the combination buprenorphine/naloxone for office-based treatment of opiate dependence have increased the options available for college students and their healthcare providers. The authors review the pharmacology of buprenorphine/naloxone and discuss how it can be implemented in college health practice. They also present a case report.
SN  - 0744-8481
AD  - Temple University's Tuttleman Counseling Services in Philadelphia, PA
U2  - PMID: 18316282.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105894474&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 110659833
T1  - The importance of stress, self-efficacy, and self-medication for pharmacological neuroenhancement among employees and students.
AU  - Maier, Larissa J.
AU  - Haug, Severin
AU  - Schaub, Michael P.
Y1  - 2015/11//
N1  - Accession Number: 110659833. Language: English. Entry Date: In Process. Revision Date: 20160409. Publication Type: Article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 7513587. 
SP  - 221
EP  - 227 7p
JO  - Drug & Alcohol Dependence
JF  - Drug & Alcohol Dependence
JA  - DRUG ALCOHOL DEPENDENCE
VL  - 156
PB  - Elsevier Science
AB  - Objectives: This study examined the relationship between stress, self-efficacy, self-medication, and pharmacological neuroenhancement (PNE) in the Swiss general population.Methods: Using the largest Swiss Internet panel, a sample of 10,171 employees and students (unweighted N=10,084) aged 15-74 years was recruited and asked to complete a self-administered online survey. The data were weighted for age, sex, and language region to provide results that were representative of the Swiss population. Multinomial logistic regression models were conducted to identify predictors of pharmacological cognitive enhancement (PCE) and pharmacological mood enhancement (PME) over the past year. Two self-medication models and an overall model were determined.Results: Current medical treatment for a mental disorder was the best predictor of both PCE and PME use as serious self-medication. The overall model revealed that cannabis use, frequent stress, and long-term stress were predictors of both PCE and PME, whereas negative stressors and time pressure at work did not remain in the final model. Furthermore, past-year PCE with and without PME was associated with being male, being a student, and using illegal drugs other than cannabis, whereas being female and having low self-efficacy predicted past-year PME only.Conclusions: Consideration of the predictor variables identified in this study may help to identify the potential PCE and PME users for whom measures to prevent drug abuse and manage stress are most appropriate. More specifically, the use of PCE and PME as self-medication to enhance performance at work or while studying needs further consideration in the neuroenhancement debate.
SN  - 0376-8716
AD  - Swiss Research Institute for Public Health and Addiction (ISGF), Associated Institute at the University of Zurich and WHO Collaborating Centre, Zurich, Switzerland
U2  - PMID: 26455555.
DO  - 10.1016/j.drugalcdep.2015.09.012
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=110659833&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104645698
T1  - The medication experience: Preliminary evidence of its value for patient education and counseling on chronic medications.
AU  - Shoemaker SJ
AU  - Ramalho de Oliveira D
AU  - Alves M
AU  - Ekstrand M
Y1  - 2011/06//
N1  - Accession Number: 104645698. Language: English. Entry Date: 20111028. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Core Nursing; Europe; Health Promotion/Education; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 8406280. 
KW  - Counseling
KW  - Drug Therapy
KW  - Patient Education
KW  - Pharmacists
KW  - Disease Management
KW  - Female
KW  - Focus Groups
KW  - Male
KW  - Middle Age
KW  - Pharmacy, Retail -- Administration
KW  - Professional-Patient Relations
SP  - 443
EP  - 450 8p
JO  - Patient Education & Counseling
JF  - Patient Education & Counseling
JA  - PATIENT EDUC COUNS
VL  - 83
IS  - 3
PB  - Elsevier Science
AB  - OBJECTIVE: To describe medication therapy management (MTM) pharmacists' encounters with patients' medication experiences, to examine the utility of the medication experience in practice, and to explore the value of the medication experience in patient education and counseling on medications. METHODS: A focus group of 10 MTM pharmacists, and 1 pharmacist's 9-month practice diary were analyzed to reveal patients' medication experiences and the utility and value of the medication experience in practice. RESULTS: MTM pharmacists commonly encountered patients' medication experiences in their practices. The medication experience was often at the root of drug therapy problems (DTPs) the practitioners identified. The pharmacists identified several examples of drug therapy problems with an associated medication experience at the root. The medication experience was a meaningful construct to guide patient education and counseling on new chronic medications to ultimately prevent DTPs, and valuable for tailoring patient education and counseling on medications to resolve DTPs. CONCLUSION: Our study provides preliminary evidence of the value of the medication experience for patient education and counseling on chronic medications in practice. PRACTICE IMPLICATIONS: The medication experience is a valuable tool for practitioners to understand patients' needs, identify and resolve DTPs, and tailor patient education and counseling for chronic medications.
SN  - 0738-3991
AD  - Abt Associates Inc., Health Policy Practice, Cambridge, USA.
U2  - PMID: 21435815.
DO  - 10.1016/j.pec.2011.02.007
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104645698&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104337195
T1  - The Neuroscience Behind Drugs of Abuse: A PharmD Service-Learning Project.
AU  - Surratt, Christopher K.
AU  - Desselle, Shane P.
Y1  - 2004/11//
N1  - Accession Number: 104337195. Language: English. Entry Date: 20130301. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; USA. 
SP  - 1
EP  - 8 8p
JO  - American Journal of Pharmaceutical Education
JF  - American Journal of Pharmaceutical Education
JA  - AM J PHARMACEUTICAL EDUC
VL  - 68
IS  - 4
CY  - Alexandria, Virginia
PB  - American Association of Colleges of Pharmacy
SN  - 0002-9459
AD  - Mylan School of Pharmacy, Duquesne University
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104337195&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 103899065
T1  - The opioid abuse and misuse epidemic: Implications for pharmacists in hospitals and health systems.
AU  - Cobaugh, Daniel J.
AU  - Gainor, Carl
AU  - Gaston, Cynthia L.
AU  - Tai C. Kwong
AU  - Magnani, Barbarajean
AU  - Mcpherson, Mary Lynn
AU  - Painter, Jacob T.
AU  - Krenzelok, Edward P.
Y1  - 2014/09/15/
N1  - Accession Number: 103899065. Language: English. Entry Date: 20140930. Revision Date: 20150710. Publication Type: Journal Article; pictorial; practice guidelines; review; statistics; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. Special Interest: Pain and Pain Management. NLM UID: 9503023. 
KW  - Substance Abuse -- Epidemiology -- United States
KW  - Analgesics, Opioid -- Metabolism
KW  - Overdose -- Drug Therapy
KW  - Inappropriate Prescribing -- Prevention and Control
KW  - Pharmacists
KW  - Professional Role
KW  - Hospital Policies
KW  - Drug Monitoring
KW  - Drugs, Prescription
KW  - United States
SP  - 1539
EP  - 1554 16p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 71
IS  - 18
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
AB  - Purpose. The current epidemic of prescription opioid abuse and misuse in the United States is discussed, with an emphasis on the pharmacist’s role in ensuring safe and effective opioid use. Summary. U.S. sales of prescription opioids increased fourfold from 1999 to 2010, with an alarming rise in deaths and emergency department visits associated with the use of fentanyl, hydrocodone, oxycodone, and other opioid medications. Signs and symptoms of opioid toxicity may include altered mental status, hypoventilation, decreased bowel motility, central nervous system and respiratory depression, peripheral vasodilation, pulmonary edema, hypotension, bradycardia, and seizures. In patients receiving long-term opioid therapy for chronic pain, urine drug testing is an important tool for monitoring and assessment of therapy; knowledge of opioid metabolic pathways and assay limitations is essential for appropriate use and interpretation of screening and confirmatory tests. In recent years, there has been an increase in federal enforcement actions against pharmacies and prescription drug wholesalers involved in improper opioid distribution, as well as increased reliance on state-level prescription drug monitoring programs to track patterns of opioid use and improper sales. Pharmacies are urged to implement or promote appropriate guidelines on opioid therapy, including the use of pain management agreement plans; policies to ensure adequate oversight of opioid prescribing, dispensing, and waste disposal; and educational initiatives targeting patients as well as hospital and pharmacy staff. Conclusion. Pharmacists in hospitals and health systems can play a key role in recognizing the various forms of opioid toxicity and in preventing inappropriate prescribing and diversion of opioids.
SN  - 1079-2082
AD  - Vice President, ASHP Research and Education Foundation, Bethesda, MD.
AD  - Clinical Assistant Professor, Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA.
AD  - Medication Use Policy Analyst, UW Health, Madison, WI.
AD  - Professor, Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY.; Director, Hematology and Chemistry Labs, Strong Memorial Hospital, University of Rochester Medical Center, Rochester, NY.
AD  - Chair and Pathologist-in-Chief, Department of Pathology and Laboratory Medicine, Tufts Medical Center, Tufts University School of Medicine, Boston, MA.; Professor and Chair, Department of Anatomic and Clinical Pathology, Tufts University School of Medicine, Boston, MA.
AD  - Professor and Vice Chair, Department of Pharmacy Practice and Science, University of Maryland School of Pharmacy, Baltimore.
AD  - Assistant Professor, Pharmaceutical Evaluation and Policy, University of Arkansas for Medical Sciences, Little Rock.
AD  - Professor Emeritus, School of Pharmacy, University of Pittsburgh.
U2  - PMID: 25174015.
DO  - 10.2146/ajhp140157
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106216145
T1  - The other youth drug problem.
AU  - Reder A
Y1  - 2006/12//2006 Dec
N1  - Accession Number: 106216145. Language: English. Entry Date: 20070119. Revision Date: 20150711. Publication Type: Journal Article; pictorial. Journal Subset: Alternative/Complementary Therapies; Consumer Health; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Consumer Health; Pediatric Care; Psychiatry/Psychology. NLM UID: 9424597. 
KW  - Drug Utilization
KW  - Mental Disorders -- Drug Therapy -- In Infancy and Childhood
KW  - Psychotropic Drugs -- Therapeutic Use -- In Infancy and Childhood
KW  - Adolescence
KW  - Child
KW  - Information Resources
KW  - Marketing
KW  - Pharmaceutical Companies
SP  - 64
EP  - 90 6p
JO  - Alternative Medicine Magazine (1081-4000)
JF  - Alternative Medicine Magazine (1081-4000)
JA  - ALTERN MED
IS  - 92
CY  - Boulder, Colorado
PB  - PH Innovisions Magazine Operating LLC
AB  - Teaching our kids to 'just say no' may keep them off street drugs, but what do we do when the schools, government, and pharmaceutical companies partner to push another kind of dangerous drug?
SN  - 1081-4000
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106216145&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107182815
T1  - The role of Glasgow pharmacists in the management of drug misuse.
AU  - Roberts K
AU  - McNulty H
AU  - Gruer L
AU  - Scott R
AU  - Bryson S
Y1  - 1998/06//1998 Jun 1
N1  - Accession Number: 107182815. Language: English. Entry Date: 19990501. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9014759. 
KW  - Pharmacists -- Scotland
KW  - Methadone -- Administration and Dosage
KW  - Substance Abuse -- Scotland
KW  - Needle Exchange Programs -- Scotland
KW  - Professional Role
KW  - Scotland
SP  - 187
EP  - 194 8p
JO  - International Journal of Drug Policy
JF  - International Journal of Drug Policy
JA  - INT J DRUG POLICY
VL  - 9
IS  - 3
CY  - New York, New York
PB  - Elsevier Science
AB  - This paper outlines the evolution of the role played by pharmacists in Greater Glasgow, initially in sales of needles and syringes and then as free exchanges, but more recently in supervising the administration of methadone, monitoring health and giving feedback on the extent of the problem of unsupervised methadone. The introduction in 1994 of supervised self-administration of methadone by community pharmacists promoted full patient compliance with the methadone regimen and reduced seepage of the drug to the illicit market. Methadone clients in Glasgow are thereby ensured daily contact with a health professional who can provide informed advice on a wide range of relevant health related topics. Of the 213 Boards, 145 pharmacies are now supervising the consumption of methadone on their premises, 11 are providing free needle and syringe exchange and a further 27 sell injecting equipment. The total number of methadone doses issued is around 40000 per month and, of these, supervised doses account for around 30000 per month. Pharmacy needle exchanges account for the free supply of around 4000 needles and syringes per month together with sales of a further 8600 from community pharmacies. The Glasgow model has been commended by the English Department of Health, the Scottish Office and the Royal Pharmaceutical Society of Great Britain and is now being reproduced throughout the United Kingdom. This paper includes advice on factors to be considered when establishing a similar service elsewhere. Educational opportunities for pharmacists are described along with professional support mechanisms. (c) 1998 Elsevier Science B.V. All rights reserved.
SN  - 0955-3959
AD  - Greater Glasgow Community and Mental Health Services NHS Trust, Department of Public Health, Dalian House, PO Box 15327, 350 St. Vincent St., Glasgow G38YU, UK
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105128520
T1  - The role of pharmacists in smoking cessation in poland.
AU  - Goniewicz ML
AU  - Lingas EO
AU  - Czogala J
AU  - Koszowski B
AU  - Zielinska-Danch W
AU  - Sobczak A
Y1  - 2010/03//
N1  - Accession Number: 105128520. Language: English. Entry Date: 20101112. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Health Services Administration; Peer Reviewed; USA. Special Interest: Quality Assurance. NLM UID: 7805992. 
KW  - Pharmacy, Retail
KW  - Pharmacists
KW  - Professional Role
KW  - Smoking -- Prevention and Control
KW  - Smoking Cessation
KW  - Adult
KW  - Age Factors
KW  - Counseling
KW  - Female
KW  - Surveys
KW  - Attitude to Health
KW  - Human
KW  - Male
KW  - Patient Education
KW  - Poland
KW  - Sex Factors
KW  - Smoking -- Drug Therapy
KW  - Smoking -- Epidemiology
KW  - Students, Pharmacy
SP  - 81
EP  - 95 15p
JO  - Evaluation & the Health Professions
JF  - Evaluation & the Health Professions
JA  - EVAL HEALTH PROF
VL  - 33
IS  - 1
CY  - Thousand Oaks, California
PB  - Sage Publications Inc.
AB  - In Poland, 38.0% of men and 25.6% of women smoke daily. One method for expanding access to smoking cessation services is through community-based pharmacists. Surveys were administered in 2007-2008 to (a) current smokers, (b) members of a pharmacy association, and (c) pharmacy students in their final year of training. Pharmacists were the highest ranked health professionals to whom Polish smokers reported they would turn for information about pharmacological support for smoking cessation. Most pharmacists (79%) reported their knowledge allowed them to provide basic smoking cessation information to their patients. Pharmacy students reported being more able to provide information about the health consequences of tobacco smoking than to help patients quit smoking (85% vs. 61%). In Poland, community-based pharmacists are positioned to provide smoking cessation interventions to all segments of the population. To extend and promote smoking cessation efforts, comprehensive tobacco cessation training should be a required component of the pharmacy school curriculum.
SN  - 0163-2787
AD  - Medical University of Silesia, Katowice, Poland. mgoniewicz@wp.pl.
U2  - PMID: 20042417.
DO  - 10.1177/0163278709356190
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105128520&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105826281
T1  - The simulation of addiction: pharmacological and neurocomputational models of drug self-administration.
AU  - Ahmed SH
AU  - Bobashev G
AU  - Gutkin BS
Y1  - 2007/10/08/
N1  - Accession Number: 105826281. Language: English. Entry Date: 20080307. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology. NLM UID: 7513587. 
KW  - Decision Making
KW  - Models, Theoretical
KW  - Self Administration
KW  - Substance Use Disorders -- Epidemiology
SP  - 304
EP  - 311 8p
JO  - Drug & Alcohol Dependence
JF  - Drug & Alcohol Dependence
JA  - DRUG ALCOHOL DEPENDENCE
VL  - 90
IS  - 2/3
PB  - Elsevier Science
AB  - In an attempt to better understand the pharmacological and neurobiological determinants of drug addiction, researchers have begun to build mathematical and computational models of drug self-administration. Quantitative pharmacological models have been developed to describe the acquisition of drug self-administration behavior and the maintenance of drug use behavior. However, models that describe behavior acquisition are unable to explain behavior maintenance, and vice versa. Recently, computational modeling has been used to develop more neurobiologically realistic models with the potential to explain drug self-administration across all major behavioral stages (i.e., initiation, escalation and maintenance)and across a wide range of reinforcement contingencies. Intrigued by the apparent irrational behavior of drug addicts, researchers from a wide range of scientific disciplines have formulated a plethora of theoretical schemes over the years to understand addiction. However, most of these models are qualitative in nature and are formulated using terms that are often ill-defined. As a result, the empirical validity of these models has been difficult to test rigorously, which has served to generate more controversy than clarity. In this context, as in other scientific fields, mathematical and computational modeling may contribute to the development of more testable and rigorous models of addiction. Recently, several researchers have begun to simulate drug self-administration behavior in an attempt to better understand the pharmacological and neurobiological determinants of drug addiction. This article stems from a 2006 College on Problems of Drug Dependence (CPDD) workshop and includes a few examples of mathematical and computational models of drug self-administration in rodents that illustrate the contribution of mathematical modeling to our understanding of the pharmacological and neurobiological factors in drug self-administration.
SN  - 0376-8716
U2  - PMID: 17944023.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105826281&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104782126
T1  - The treatment of benzodiazepine dependence.
AU  - Ashton, H
Y1  - 1994/11//
N1  - Accession Number: 104782126. Language: English. Entry Date: 20110610. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9304118. 
KW  - Antianxiety Agents -- Administration and Dosage
KW  - Antianxiety Agents -- Adverse Effects
KW  - Substance Use Disorders -- Rehabilitation
KW  - Behavior Therapy
KW  - Antianxiety Agents, Benzodiazepine
KW  - Combined Modality Therapy
KW  - Dose-Response Relationship, Drug
KW  - Drug Administration Schedule
KW  - Prospective Studies
KW  - Human
KW  - Substance Withdrawal Syndrome -- Psychosocial Factors
KW  - Substance Withdrawal Syndrome -- Rehabilitation
KW  - Substance Use Disorders -- Psychosocial Factors
KW  - Treatment Outcomes
SP  - 1535
EP  - 1541 7p
JO  - Addiction
JF  - Addiction
JA  - ADDICTION
VL  - 89
IS  - 11
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Withdrawal of benzodiazepines is currently advised for long-term benzodiazepine users because of doubts about continued efficacy, risks of adverse effects, including dependence and neuropsychological impairment and socio-economic costs. About half a million people in the UK may need advice on withdrawal. Successful withdrawal strategies should combine gradual dosage reduction and psychological support. The benzodiazepine dosage should be tapered at an individually titrated rate which should usually be under the patient's control. The whole process may take weeks or months. Withdrawal from diazepam is convenient because of available dosage strengths, but can be carried out directly from other benzodiazepine. Adjuvant medication may occasionally be required (antidepressants, propranolol) but no drugs have been proved to be of general utility in alleviating withdrawal-related symptoms. Psychological support should be available both during dosage reduction and for some months after cessation of drug use. Such support should include the provision of information about benzodiazepines, general encouragement, and measures to reduce anxiety and promote the learning of non-pharmacological ways of coping with stress. For many patients the degree of support required is minimal; a minority may need counselling or formal psychological therapy. Unwilling patients should not be forced to withdraw. With these methods, success rates of withdrawal are high and are unaffected by duration of usage, dosage or type of benzodiazepine, rate of withdrawal, symptom severity, psychiatric history or personality disorder. Longer-term outcome is less clear; a considerable proportion of patients may temporarily take benzodiazepines again and some need other psychotropic medication. However, the outcome may be improved by careful pharmacological and psychological handling of withdrawal and post-withdrawal phases.
SN  - 0965-2140
AD  - Department of Pharmacological Sciences, University of Newcastle upon Tyne, UK.
U2  - PMID: 7841868.
DO  - 10.1111/j.1360-0443.1994.tb03755.x
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104782128
T1  - The treatment of stimulant dependence.
AU  - Schuckit, M A
Y1  - 1994/11//
N1  - Accession Number: 104782128. Language: English. Entry Date: 20110610. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9304118. 
KW  - Amphetamines -- Adverse Effects
KW  - Central Nervous System Stimulants -- Adverse Effects
KW  - Cocaine -- Adverse Effects
KW  - Substance Use Disorders -- Rehabilitation
KW  - Combined Modality Therapy
KW  - Recurrence
SP  - 1559
EP  - 1563 5p
JO  - Addiction
JF  - Addiction
JA  - ADDICTION
VL  - 89
IS  - 11
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Rehabilitation efforts offered to individuals with stimulant dependence incorporate a series of maneuvers to accomplish three major goals. Following active detoxification, most clinicians attempt to: (1) increase motivation for abstinence and maintain a high level of commitment to this goal; (2) help individuals to rebuild a stable life-style without substances; and (3) actively work toward ways of decreasing the probability of relapse (relapse prevention). While these activities incorporate education, counseling, outreach to families and exposure to self-help groups (e.g. Cocaine Anonymous), numerous pharmacological approaches have been tested. Each mode of drug therapy is based on a reasonable hypothesis, but appropriately controlled and structured clinical trials have not yet revealed any pharmacological approach for rehabilitation of stimulant-dependent individuals for which the risks have been shown to outweight the assets.
SN  - 0965-2140
AD  - Veterans Affairs Medical Center, San Diego, CA 92161.
U2  - PMID: 7841871.
DO  - 10.1111/j.1360-0443.1994.tb03758.x
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104782128&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106768928
T1  - The young adult with hip pain: diagnosis and medical treatment, circa 2004.
AU  - Troum OM
AU  - Crues JV III
Y1  - 2004/01//2004 Jan
N1  - Accession Number: 106768928. Language: English. Entry Date: 20040820. Revision Date: 20150711. Publication Type: Journal Article; diagnostic images; review; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0075674. 
KW  - Diagnosis, Differential -- In Adulthood
KW  - Hip -- Pathology -- In Adulthood
KW  - Pain -- Etiology -- In Adulthood
KW  - Pain -- Therapy -- In Adulthood
KW  - Acetaminophen -- Therapeutic Use
KW  - Adrenal Cortex Hormones -- Therapeutic Use
KW  - Adult
KW  - Alcoholism
KW  - Antibiotics -- Therapeutic Use
KW  - Antiinflammatory Agents, Non-Steroidal -- Therapeutic Use
KW  - Arthritis
KW  - Arthritis, Rheumatoid
KW  - Arthroplasty, Replacement, Hip
KW  - Athletic Injuries
KW  - Blood Chemical Analysis
KW  - Diagnostic Imaging
KW  - Hip Dislocation, Congenital
KW  - Hip Fractures
KW  - Hip -- Radiography
KW  - Infection -- Diagnosis
KW  - Inflammation -- Diagnosis
KW  - Magnetic Resonance Imaging
KW  - Narcotics -- Therapeutic Use
KW  - Necrosis
KW  - Osteoarthritis
KW  - Pain -- Drug Therapy
KW  - Patient Education
KW  - Physical Therapy
KW  - Reoperation
KW  - Rheumatic Diseases -- Diagnosis
KW  - Substance Abuse, Intravenous
KW  - Synovial Fluid -- Analysis
KW  - Trauma
KW  - Urinalysis
SP  - 9
EP  - 17 9p
JO  - Clinical Orthopaedics & Related Research
JF  - Clinical Orthopaedics & Related Research
JA  - CLIN ORTHOP RELATED RES
VL  - 418
CY  - , <Blank>
PB  - Springer Science & Business Media B.V.
AB  - Hip pain in young adults (18-35 years old) often is characterized by nonspecific symptoms, normal imaging studies, and vague findings from the history and physical examination. In younger patients, pain is more likely to be caused by congenital hip dysplasia, athletic injuries, trauma, spondyloarthropathy, and by conditions that first appear during this stage of life, such as rheumatoid arthritis, osteoarthritis, intravenous drug use, alcoholism, or corticosteroid use. The history and physical examination may narrow the diagnosis to intraarticular, extraarticular, or referred sources of pain. Plain radiography and magnetic resonance imaging are the preferred initial imaging procedures. Analyses of the blood, urine, and synovial fluid can be helpful in diagnosing inflammation, infection, and systematic rheumatic disease. Fractures, infection, and ischemic necrosis should be ruled out early because they require immediate treatment to prevent damage to the joint. Hip trauma at a young age increases the risk of osteoarthritis with advancing age, and, unlike most older adults, young adults receiving total hip replacement can expect revision surgery. Medical treatment often involves patient education, physical therapy, and pharmacotherapy. Acetaminophen, nonsteroidal anti-inflammatory drugs, and opioids for pain and antibiotics for infection are the most often prescribed drugs for this population.
SN  - 0009-921X
AD  - Division of Rheumatology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA; Otroum@yahoo.com
U2  - PMID: 15043086.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106768928&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105838621
T1  - Tobacco cessation interventions for young people.
AU  - Stanton A
AU  - Grimshaw G
Y1  - 2013/08//
N1  - Accession Number: 105838621. Language: English. Entry Date: 20101029. Revision Date: 20150711. Publication Type: Journal Article; research; systematic review. Journal Subset: Europe; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice. NLM UID: 100909747. Cochrane AN: CD003289. 
KW  - Smoking Cessation -- In Adolescence
KW  - Adolescence
KW  - Behavior Therapy
KW  - Bupropion -- Therapeutic Use
KW  - Clinical Trials
KW  - Confidence Intervals
KW  - Motivational Interviewing
KW  - Nicotine Replacement Therapy
KW  - Odds Ratio
KW  - Transtheoretical Stages of Change Model
KW  - Treatment Outcomes
KW  - Human
SP  - N.PAG
EP  - N.PAG 1p
JO  - Cochrane Database of Systematic Reviews
JF  - Cochrane Database of Systematic Reviews
JA  - COCHRANE DATABASE SYST REV
IS  - 8
CY  - , <Blank>
PB  - John Wiley & Sons, Inc.
AB  - Most tobacco control programmes for adolescents are based around prevention of uptake, but teenage smoking is still common. It is unclear if interventions that are effective for adults can also help adolescents to quit. This is the second update of a Cochrane review first published in 2006. To evaluate the effectiveness of strategies that help young people to stop smoking tobacco. We searched the Cochrane Tobacco Addiction Group's Specialized Register in February 2013. This includes reports for trials identified in the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE and PsyclNFO. We included randomized controlled trials, cluster-randomized controlled trials and other controlled trials recruiting young people, aged less than 20, who were regular tobacco smokers. We included any interventions; these could include pharmacotherapy, psycho-social interventions and complex programmes targeting families, schools or communities. We excluded programmes primarily aimed at prevention of uptake. The primary outcome was smoking status after at least six months follow-up among those who smoked at baseline. Both authors independently assessed the eligibility of candidate trials and extracted data. Included studies were evaluated for risk of bias using standard Cochrane methodology. Where meta-analysis was appropriate, we estimated pooled risk ratios using a Mantel-Haenszel fixed-effect method, based on the quit rates at longest follow-up. Twenty-eight trials involving approximately 6000 young people met our inclusion criteria (12 cluster-randomized controlled trials, 14 randomized controlled trials and 2 controlled trials). The majority of studies were judged to be at high or unclear risk of bias in at least one domain. Many studies combined components from various theoretical backgrounds to form complex interventions.The majority used some form of motivational enhancement combined with psychological support such as cognitive behavioural therapy (CBT) and some were tailored to stage of change using the transtheoretical model (TTM). Three trials based mainly on TTM interventions achieved moderate long-term success, with a pooled risk ratio (RR) of 1.56 at one year (95% confidence interval (CI) 1.21 to 2.01). The 12 trials that included some form of motivational enhancement gave an estimated RR of 1.60 (95% CI 1.28 to 2.01). None of the 13 individual trials of complex interventions that included cognitive behavioural therapy achieved statistically significant results, and results were not pooled due to clinical heterogeneity. There was a marginally significant effect of pooling six studies of the Not on Tobacco programme (RR of 1.31, 95% CI 1.01 to 1.71), although three of the trials used abstinence for as little as 24 hours at six months as the cessation outcome. A small trial testing nicotine replacement therapy did not detect a statistically significant effect. Two trials of bupropion, one testing two doses and one testing it as an adjunct to NRT, did not detect significant effects. Studies of pharmacotherapies reported some adverse events considered related to study treatment, though most were mild, whereas no adverse events were reported in studies of behavioural interventions. Complex approaches show promise, with some persistence of abstinence (30 days point prevalence abstinence or continuous abstinence at six months), especially those incorporating elements sensitive to stage of change and using motivational enhancement and CBT. Given the episodic nature of adolescent smoking, more data is needed on sustained quitting. There were few trials with evidence about pharmacological interventions (nicotine replacement and bupropion), and none demonstrated effectiveness for adolescent smokers. There is not yet sufficient evidence to recommend widespread implementation of any one model. There continues to be a need for well-designed adequately powered randomized controlled trials of interventions for this population of smokers.[CINAHL Note: The Cochrane Collaboration systematic reviews contain interactive software that allows various calculations in the MetaView.]
SN  - 1469-493X
U2  - PMID: 23975659.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104285431
T1  - Tobacco dependence diagnosis and treatment in Veterans Health Administration residential substance use disorder treatment programs.
AU  - Gifford, Elizabeth V.
AU  - Tavakoli, Sara
AU  - Wang, Ruey
AU  - Hagedorn, Hildi J.
AU  - Hamlett-Berry, Kim W.
Y1  - 2013/06//
N1  - Accession Number: 104285431. Language: English. Entry Date: 20130515. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Psychiatry/Psychology. Grant Information: This study was supported by the US Department of Veterans Affairs Office of Public Health, and by the Health Services Research and Development Service, Quality Enhancement Research Initiative.. NLM UID: 9304118. 
KW  - Substance Use Disorders -- Diagnosis
KW  - Smoking -- Drug Therapy
KW  - Substance Use Disorders -- Drug Therapy
KW  - Substance Use Rehabilitation Programs
KW  - Nicotine Replacement Therapy
KW  - Human
KW  - United States Department of Veterans Affairs
KW  - United States
KW  - Funding Source
KW  - Retrospective Design
KW  - Logistic Regression
KW  - Veterans
KW  - Data Analysis Software
KW  - Male
KW  - Female
KW  - Adult
KW  - Middle Age
KW  - Descriptive Statistics
KW  - Chi Square Test
SP  - 1127
EP  - 1135 9p
JO  - Addiction
JF  - Addiction
JA  - ADDICTION
VL  - 108
IS  - 6
CY  - Malden, Massachusetts
PB  - Wiley-Blackwell
AB  - Aims To explore tobacco dependence ( TD) diagnosis and treatment utilization, and identify predictors of nicotine replacement therapy ( NRT) among veterans with substance use disorders ( SUDs) enrolled in Veterans Health Administration ( VHA) SUD residential treatment programs ( SRTPs). Design Retrospective cohort study. Setting VHA SRTPs, which treat veterans with SUD and multiple severe psychosocial deficits, from 1 October 2009 to 31 September 2010. Participants Identified tobacco users among veterans with SUD treated in SRTPs during fiscal year 2010 ( FY10). Measurements Rates of documented TD diagnosis and pharmacotherapy were assessed nationally, regionally and by facility. Patient-level predictors of NRT were examined using a mixed-effects logistic regression model with facility as a random effect. Findings A total of 12 097 of the 15 320 veterans in SRTPs in FY10 (79%) were identified as probable tobacco users. Among these, 33% had a documented TD diagnosis, 34% were treated with pharmacotherapy and only 11% were both diagnosed and treated for TD while in SRTP. NRT was more common among patients with a current documented TD diagnosis, recent history of TD treatment, comorbid mental health disorder, age 55 years or younger and identified as white. Conclusions Most veterans in Veterans Health Administration substance use disorders residential treatment programs appear to use tobacco, yet only one in 10 receives a documented ICD-9 TD diagnosis and pharmacotherapy while in a substance use disorders residential treatment program.
SN  - 0965-2140
AD  - Center for Health Care Evaluation, VA Palo Alto Health Care System and Stanford University School of Medicine
AD  - Minneapolis VA Medical Center
AD  - Department of Veterans Affairs Clinical Public Health Group, Office of Public Health
U2  - PMID: 23297756.
DO  - 10.1111/add.12105
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106362573
T1  - Tobacco sales in pharmacies: time to quit.
AU  - Hudmon KS
AU  - Fenlon CM
AU  - Corelli RL
AU  - Prokhorov AV
AU  - Schroeder SA
Y1  - 2006/02//
N1  - Accession Number: 106362573. Language: English. Entry Date: 20061117. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; Public Health; UK & Ireland. NLM UID: 9209612. 
KW  - Business -- Methods
KW  - Pharmacists -- Psychosocial Factors
KW  - Pharmacy, Retail
KW  - Students, Pharmacy -- Psychosocial Factors
KW  - Tobacco
KW  - Adolescence
KW  - Adult
KW  - Aged
KW  - Aged, 80 and Over
KW  - Attitude of Health Personnel
KW  - Attitude to Health
KW  - California
KW  - Descriptive Statistics
KW  - Female
KW  - Funding Source
KW  - Interviews
KW  - Mail
KW  - Male
KW  - Middle Age
KW  - Pharmacists
KW  - Questionnaires
KW  - Smoking -- Psychosocial Factors
KW  - Social Behavior
KW  - Students, Pharmacy
KW  - Survey Research
KW  - T-Tests
KW  - Telephone
KW  - Human
SP  - 35
EP  - 38 4p
JO  - Tobacco Control
JF  - Tobacco Control
JA  - TOBACCO CONTROL
VL  - 15
IS  - 1
PB  - BMJ Publishing Group
AB  - OBJECTIVE: To assess the pharmacy profession's perceptions of tobacco sales in US pharmacies and explore whether a policy prohibiting sales of tobacco in pharmacies would alter adult consumer shopping behaviour. SUBJECTS AND DESIGN: In California, surveys were administered to 1168 licensed pharmacists and 1518 pharmacy students, and telephone interviews were conducted with 988 adult consumers. RESULTS: Most (58.1%) licensed pharmacists were strongly against sales of tobacco in pharmacies, 23.6% were against it, 16.7% were neutral, 1.2% were in favour of it, and 0.4% were strongly in favour of it. Pharmacists who were current tobacco users were more likely to be in favour of tobacco sales in pharmacies than were pharmacists who were current non-users (p < 0.005). Similar statistics were observed for pharmacy students. Most consumers (72.3%) disagreed with the statement, 'I am in favour of tobacco products being sold in drugstores'; 82.6% stated that if the drugstore where they most commonly shopped were to stop selling tobacco products, they would shop there just as often, 14.2% would shop there more often, and 3.2% would shop there less often. CONCLUSION: Little professional or public support exists for tobacco sales in pharmacies.
SN  - 0964-4563
AD  - Department of Epidemiology & Public Health, Yale University School of Medicine, New Haven, CT 06520; karen.hudmon@yale.edu
U2  - PMID: 16436403.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105406427
T1  - Tobacco treatment and prevention: what works and why.
AU  - Goodfellow LT
AU  - Waugh JB
Y1  - 2009/08//
N1  - Accession Number: 105406427. Language: English. Entry Date: 20091009. Revision Date: 20150819. Publication Type: Journal Article; tables/charts. Journal Subset: Allied Health; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 7510357. 
KW  - Lung Diseases, Obstructive
KW  - Smoking Cessation
KW  - Smoking -- Prevention and Control
KW  - Bupropion -- Administration and Dosage
KW  - Clonidine -- Administration and Dosage
KW  - Information Resources
KW  - Legislation
KW  - Nicotine Replacement Therapy
KW  - Professional Role
KW  - Respiratory Therapists
KW  - Smoking -- Drug Therapy
KW  - Smoking -- Legislation and Jurisprudence -- United States
KW  - United States
KW  - World Wide Web
SP  - 1082
EP  - 1090 9p
JO  - Respiratory Care
JF  - Respiratory Care
JA  - RESPIR CARE
VL  - 54
IS  - 8
CY  - Irving, Texas
PB  - Daedalus Enterprises, Inc.
AB  - Tobacco abuse is one of the main reasons that chronic obstructive pulmonary disease is the fourth leading cause of death in the United States. Many people kick the habit easily, while others struggle through a difficult cycle of addiction. Respiratory therapists often have contact with patients with chronic lung disease who want to quit smoking but do not know where to begin. Smoking bans and clean air laws are in place across the United States, but this is not enough for a complete tobacco treatment and prevention program. For any successful disease-management program, tobacco-control education and support must be included. Studies show that when pharmacologic interventions are used along with the appropriate counseling and other resources, the success of tobacco cessation increases. This must be understood, because if the regulatory efforts of our governing bodies are not enough and if patients do not receive the care that is essential for disease management and rehabilitation, then how will our role as respiratory therapist matter in any health-care system of the future? The respiratory therapist plays a key role in asking patients, especially newly diagnosed patients with chronic lung disease, if they are smokers and if they are interested in tobacco use interventions. This is a role that should not be taken lightly.
SN  - 0020-1324
AD  - Respiratory Care Program, Georgia State University, PO Box 4019, Atlanta, GA 30302. ltgoodfellow@gsu.edu.
U2  - PMID: 19650948.
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105388017
T1  - Tobacco use and cessation counselling: cross-country. Data from the Global Health Professions Student Survey (GHPSS), 2005-7.
AU  - Warren CW
AU  - Jones NR
AU  - Chauvin J
AU  - Peruga A
Y1  - 2008/08//
N1  - Accession Number: 105388017. Corporate Author: GTSS Collaborative Group. Language: English. Entry Date: 20090731. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Blind Peer Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; Public Health; UK & Ireland. Special Interest: Public Health. NLM UID: 9209612. 
KW  - Attitude of Health Personnel
KW  - Attitude to Health
KW  - Counseling
KW  - Smoking Cessation
KW  - Smoking -- Prevention and Control
KW  - Students, Health Occupations -- Psychosocial Factors
KW  - Adult
KW  - Female
KW  - Male
KW  - Professional Role
KW  - Human
SP  - 238
EP  - 247 10p
JO  - Tobacco Control
JF  - Tobacco Control
JA  - TOBACCO CONTROL
VL  - 17
IS  - 4
PB  - BMJ Publishing Group
AB  - BACKGROUND: Brief intervention by a health professional can substantially increase smoking cessation rates among patients. However, few studies have collected information on tobacco use and training to provide cessation counselling among health professional students. OBJECTIVE: To examine tobacco use prevalence and tobacco cessation training among students pursuing advanced degrees in health professions. METHODS: The Global Health Professions Student Survey (GHPSS) has been conducted among third-year students attending dental, medical, nursing and pharmacy schools. The GHPSS was conducted in schools during regular lectures and class sessions. GHPSS follows an anonymous, self-administered format for data collection. RESULTS: The GHPSS was completed by at least one of the four target disciplines in 31 countries between 2005 and 2007 for a total of 80 survey sites. In 47 of the 80 sites, over 20% of the students currently smoked cigarettes; and in 29 of 77 sites, over 10% of the students currently used other tobacco products. GHPSS data showed that the majority of health professional students recognised that they are role models in society, believed that they should receive training on counselling patients to quit using tobacco, but in 73 of 80 sites less than 40% of the students reported they received such training. CONCLUSIONS: Health professional schools, public health organisations and education officials should discourage tobacco use among health professionals and work together to design and implement programmes that train all health professionals in effective cessation counselling techniques. If the goal of the tobacco control community is to reduce substantially the use of tobacco products, then resources should be invested in improving the quality of education of health professionals with respect to tobacco control.
SN  - 0964-4563
AD  - Centers for Disease Control and Prevention, Office on Smoking and Health, 4770 Buford Hwy NE, MS-K50, Atlanta, GA 30341-3717, USA. wcw1@cdc.gov
U2  - PMID: 18474539.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105388017&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 99148564
T1  - Touro University.
AU  - Shah, Ravi
Y1  - 2014///Summer2014
N1  - Accession Number: 99148564. Language: English. Entry Date: 20141104. Revision Date: 20141104. Publication Type: Article. Journal Subset: Biomedical; USA. 
KW  - Colleges and Universities
KW  - Pharmacists -- Education
KW  - California
KW  - Serial Publications
KW  - Students, Pharmacy
KW  - Academic Medical Centers
KW  - Substance Abuse -- Prevention and Control
KW  - Membership
SP  - 56
EP  - 56 1/2p
JO  - California Pharmacist
JF  - California Pharmacist
JA  - CALIF PHARMACIST
VL  - 61
IS  - 3
CY  - Sacramento, California
PB  - California Pharmacists Association
SN  - 0739-0483
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107771454
T1  - Touro University.
AU  - Shah, Ravi
Y1  - 2014///Summer2014
N1  - Accession Number: 107771454. Language: English. Entry Date: 20141104. Revision Date: 20150712. Publication Type: Journal Article; pictorial. Journal Subset: Biomedical; USA. 
KW  - Colleges and Universities
KW  - Pharmacists -- Education
KW  - California
KW  - Serial Publications
KW  - Students, Pharmacy
KW  - Academic Medical Centers
KW  - Substance Abuse -- Prevention and Control
KW  - Membership
SP  - 56
EP  - 56 1p
JO  - California Pharmacist
JF  - California Pharmacist
JA  - CALIF PHARMACIST
VL  - 61
IS  - 3
CY  - Sacramento, California
PB  - California Pharmacists Association
SN  - 0739-0483
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107771454&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105222482
T1  - Treatment of alcohol dependence.
AU  - Hanwella R
AU  - de Silva V
Y1  - 2009/06//2009 Jun
N1  - Accession Number: 105222482. Language: English. Entry Date: 20101015. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Asia; Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed. NLM UID: 1264702. 
KW  - Alcoholism -- Drug Therapy
KW  - Alcohol Deterrents -- Therapeutic Use
KW  - Disulfiram -- Therapeutic Use
KW  - Fructose
KW  - Fructose -- Therapeutic Use
KW  - Naltrexone -- Therapeutic Use
KW  - Narcotic Antagonists -- Therapeutic Use
KW  - Neuroprotective Agents
KW  - Alkanes
KW  - Alkanes -- Therapeutic Use
KW  - Vitamins -- Therapeutic Use
SP  - 63
EP  - 65 3p
JO  - Ceylon Medical Journal
JF  - Ceylon Medical Journal
JA  - CEYLON MED J
VL  - 54
IS  - 2
PB  - Sri Lanka Medical Association
AB  - It is important to manage alcohol withdrawal properly. Mismanagement could lead to permanent brain damage or even death. The principles are simple and easily learnt. New pharmacological agents have come into use which helps in maintaining abstinence. Clinicians should update themselves on their use.
SN  - 0009-0875
AD  - Department of Psychological Medicine, Faculty of Medicine, Colombo, Sri Lanka. raveenhanwella@yahoo.co.uk
U2  - PMID: 19670554.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105222482&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106547632
T1  - Trends in child and teen nonprescription drug abuse reported to a regional poison control center.
AU  - Crouch BI
AU  - Caravati EM
AU  - Booth J
Y1  - 2004/06/15/
N1  - Accession Number: 106547632. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. 
KW  - Drugs, Non-Prescription
KW  - Substance Abuse -- Trends -- In Adolescence
KW  - Substance Abuse -- Trends -- In Infancy and Childhood
KW  - Adolescence
KW  - Antitussive Agents
KW  - Caffeine
KW  - Central Nervous System Stimulants
KW  - Child
KW  - Convenience Sample
KW  - Descriptive Research
KW  - Descriptive Statistics
KW  - Dextromethorphan
KW  - Female
KW  - Male
KW  - Medical Records
KW  - Parasympatholytics
KW  - Poison Control Centers
KW  - Record Review
KW  - Retrospective Design
KW  - Utah
KW  - Human
SP  - 1252
EP  - 1257 6p
JO  - American Journal of Health-System Pharmacy
JF  - American Journal of Health-System Pharmacy
JA  - AM J HEALTH SYST PHARM AJHP
VL  - 61
IS  - 12
CY  - Bethesda, Maryland
PB  - American Society of Health System Pharmacists
AB  - PURPOSE: Trends in child and teen nonprescription drug abuse reported to a regional poison control center over a 10-year period were examined. METHODS: Human exposures to toxic substances reported to the Utah Poison Control Center between January 1990 and December 1999 were reviewed. Cases were selected for analysis if the exposure involved a nonprescription drug, the patient was 6-19 years old, and the reason for exposure was intentional abuse. Frequencies and cross-tabulations were calculated to identify trends in nonprescription drug abuse. RESULTS: There were 2214 reports of intentional drug abuse among children and teenagers 6-19 years old. Of those, 844 (38.1%) involved nonprescription drugs. The percentage of exposures Involving nonprescription products varied every year and declined over time. Exposures were slightly more common In males (51.7%). The site of exposure was a residence in 65% of cases and a school in 10% of cases. The majority of patients with exposures (68.4%) were treated In a health care facility. The most common types of nonprescription medications abused were drugs with anticholinergic properties, caffeine, dextromethorphan, and nonprescription stimulants. CONCLUSION: Reports of the Intentional abuse of nonprescription drugs by children and teenagers were common at a regional poison control center. There was significant variation in the type of nonprescription medication most commonly abused. The knowledge of these trends may assist public health policymakers, physicians, pharmacists, and child educators in their attempts to curb nonprescription drug abuse.
SN  - 1079-2082
AD  - Associate Professor, College of Pharmacy, University of Utah (UU), Salt Lake City, UT; barbara.crouch@hsc.utah.edu
U2  - PMID: 15259755.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106547632&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 99148563
T1  - University of the Pacific.
AU  - (April) Nguyen, Tinh An
Y1  - 2014///Summer2014
N1  - Accession Number: 99148563. Language: English. Entry Date: 20141104. Revision Date: 20141104. Publication Type: Article. Journal Subset: Biomedical; USA. 
KW  - Colleges and Universities
KW  - Pharmacists -- Education
KW  - Pharmacy and Pharmacology
KW  - Serial Publications
KW  - Female
KW  - Leadership
KW  - Smoking -- Evaluation
SP  - 55
EP  - 55 1p
JO  - California Pharmacist
JF  - California Pharmacist
JA  - CALIF PHARMACIST
VL  - 61
IS  - 3
CY  - Sacramento, California
PB  - California Pharmacists Association
SN  - 0739-0483
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=99148563&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 107771453
T1  - University of the Pacific.
AU  - (April) Nguyen, Tinh An
Y1  - 2014///Summer2014
N1  - Accession Number: 107771453. Language: English. Entry Date: 20141104. Revision Date: 20150712. Publication Type: Journal Article; pictorial; tables/charts. Journal Subset: Biomedical; USA. 
KW  - Colleges and Universities
KW  - Pharmacists -- Education
KW  - Pharmacy and Pharmacology
KW  - Serial Publications
KW  - Female
KW  - Leadership
KW  - Smoking -- Evaluation
SP  - 55
EP  - 55 1p
JO  - California Pharmacist
JF  - California Pharmacist
JA  - CALIF PHARMACIST
VL  - 61
IS  - 3
CY  - Sacramento, California
PB  - California Pharmacists Association
SN  - 0739-0483
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=107771453&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109604469
T1  - Using a virtual patient system for the teaching of pharmaceutical care.
AU  - Menendez, Elisa
AU  - Balisa-Rocha, Blície
AU  - Jabbur-Lopes, Monique
AU  - Costa, Wanderson
AU  - Nascimento, José Rafael
AU  - Dósea, Marcos
AU  - Silva, Leila
AU  - Lyra Junior, Divaldo
Y1  - 2015/09//
N1  - Accession Number: 109604469. Language: English. Entry Date: 20150923. Revision Date: 20151007. Publication Type: journal article. Journal Subset: Biomedical; Computer/Information Science; Europe; Peer Reviewed; UK & Ireland. Special Interest: Informatics. NLM UID: 9711057. 
SP  - 640
EP  - 646 7p
JO  - International Journal of Medical Informatics
JF  - International Journal of Medical Informatics
JA  - INT J MED INFORM
VL  - 84
IS  - 9
CY  - New York, New York
PB  - Elsevier Science
AB  - Purpose: The communication skills of pharmacists are essential for the identification and reduction of patient́s drug related problems. Therefore, Pharmacy courses started the process of teaching Pharmaceutical Care to students in order to improve their communication skills. The use of virtual patients (VP) has been a widely used technique in health care courses, but many of the VP tools in Pharmacy field are in English and do not have clinical cases that are common in tropical countries, such as Brazil. The aim of this work is to describe the PharmaVP system, developed with the purpose of training Latin America students in Pharmaceutical Care. The main differential of PharmaVP is the availability in three languages (Portuguese, English and Spanish) and the possibility of clinical case evolution, simulating several visits made by the patient.Methods: The system was developed according to an incremental and interactive methodology, well suited for conducting multidisciplinary projects. Real clinical cases were collected from a Pharmaceutical Care program and added in PharmaVP to simulate the virtual patients. Then, 31 students of a Pharmacy course were trained and invited to participate of the evaluation study. They used the software and answered adapted instruments that assess the students' acceptance of, use of, learning of, and satisfaction with the system.Results: The results showed that the students found the cases realistic and learned significantly using the software. Another positive point is that the application process of PharmaVP did not consume much time.Discussion: We can conclude that the virtual patient tool contributed to the development of the skills required for the practice of Pharmaceutical Care, but should be used as complementary technique.
SN  - 1386-5056
AD  - Department of Computing (DCOMP), Federal University of Sergipe, Brazil.
AD  - Laboratory of Teaching and Research in Social Pharmacy (LEPFS), Faculty of Pharmacy, Federal University of Sergipe, Brazil.
AD  - Department of Computing (DCOMP), Federal University of Sergipe, Brazil. Electronic address: leila@ufs.br.
U2  - PMID: 26077512.
DO  - 10.1016/j.ijmedinf.2015.05.015
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 109657827
T1  - Validity Evidence for FASTHUG-MAIDENS, a Mnemonic for Identifying Drug-Related Problems in the Intensive Care Unit.
AU  - Masson, Sarah C
AU  - Mabasa, Vincent H
AU  - Malyuk, Douglas L
AU  - Perrott, Jerrold L
Y1  - 2013/05//2013 May
N1  - Accession Number: 109657827. Language: English. Entry Date: 20150923. Revision Date: 20150923. Publication Type: Journal Article. Journal Subset: Biomedical; Canada. NLM UID: 0215645. 
SP  - 157
EP  - 162 6p
JO  - Canadian Journal of Hospital Pharmacy
JF  - Canadian Journal of Hospital Pharmacy
JA  - CAN J HOSP PHARM
VL  - 66
IS  - 3
CY  - Milton, Ontario
PB  - Multimed Inc.
AB  - BACKGROUND: The mnemonic FASTHUG (Feeding, Analgesia, Sedation, Thromboembolic prophylaxis, Head of bed elevation, stress Ulcer prophylaxis, Glucose control) was developed by intensive care unit (ICU) physicians to ensure that key aspects of care are addressed during each patient encounter. Because this tool does not specifically target pharmacotherapy assessments, a modified version, FASTHUG-MAIDENS, was created, by changing the H to mean Hypoactive or Hyperactive delirium and adding M for Medication reconciliation; A for Antibiotics or Anti-infectives; I for Indications for medications; D for drug Dosing; E for Electrolytes, hematology, and other laboratory tests; N for No drug interactions, allergies, duplication, or side effects; and S for Stop dates. OBJECTIVE: To validate the use of FASTHUG-MAIDENS as a tool for identifying drug-related problems (DRPs) in the ICU. METHODS: This randomized, prospective validation study took place between January and May 2011 in the ICUs of 4 hospitals: 2 community-level ICUs and 2 tertiary referral ICUs. Each ICU had a dedicated ICU pharmacist and one or more pharmacy residents completing an ICU rotation as part of their pharmacy practice residency (total of 6 residents). The 6 pharmacy residents were randomly assigned to assess patients admitted to the ICU using FASTHUG-MAIDENS or standard monitoring practice. The mean proportion of DRPs per patient encounter identified by the residents (relative to DRPs identified by the ICU pharmacists) was the primary outcome, and the proportion of total DRPs identified in each group was assessed as a secondary end point. RESULTS: Pharmacy residents using the FASTHUG-MAIDENS mnemonic identified a significantly greater mean proportion of DRPs per patient encounter (73.2% versus 52.4%, p = 0.008) and a greater proportion of total DRPs (77.1% versus 52.5%, p < 0.001) than those assessing patients according to standard monitoring practice. CONCLUSION: In this sample, the mnemonic FASTHUG-MAIDENS was a useful tool to facilitate the capture of DRPs by pharmacy residents working in the ICU.
SN  - 0008-4123
AD  - , BScPharm, ACPR, is with the Abbotsford Regional Hospital, Abbotsford, British Columbia.
U2  - PMID: 23814282.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109657827&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 106004192
T1  - Views of Ontarians about health professionals' smoking cessation advice.
AU  - Brewster JM
AU  - Victor JC
AU  - Ashley MJ
Y1  - 2007/09//Sep/Oct2007
N1  - Accession Number: 106004192. Language: English. Entry Date: 20080229. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Biomedical; Canada; Double Blind Peer Reviewed; Expert Peer Reviewed; Peer Reviewed; Public Health. Special Interest: Public Health. NLM UID: 0372714. 
KW  - Attitude to Health
KW  - Counseling -- Standards
KW  - Patient Education -- Standards
KW  - Professional-Patient Relations
KW  - Smoking Cessation
KW  - Smoking -- Psychosocial Factors
KW  - Adolescence
KW  - Adult
KW  - Female
KW  - Friendship
KW  - Male
KW  - Middle Age
KW  - Ontario
KW  - Pharmacists -- Standards
KW  - Physicians -- Standards
KW  - Smoking -- Prevention and Control
KW  - Surveys
KW  - Human
SP  - 395
EP  - 399 5p
JO  - Canadian Journal of Public Health
JF  - Canadian Journal of Public Health
JA  - CAN J PUBLIC HEALTH
VL  - 98
IS  - 5
CY  - Ottawa, Ontario
PB  - Canadian Public Health Association
AB  - BACKGROUND: Health professionals have important roles in helping smokers quit. However, it is not known how the public, especially smokers, view smoking cessation advice from different health professionals. METHODS: We added questions regarding opinions and experiences with health professionals' smoking cessation advice to the 2002 CAMH Monitor, an annual random-digit-dialled survey of adult Ontarians. We report on how good a source of advice physicians, pharmacists, and dentists are perceived to be, how likely smokers are to consult each of these professionals, who smokers would ask for advice on the use of NRT, and advice received by smokers in the past year. RESULTS: About two thirds of respondents viewed physicians as a very good source of advice on quitting, compared to just over one third and about one quarter who thought this of pharmacists and dentists, respectively. Over half of current smokers would be very likely to ask a physician for quit advice, compared to about 20% and only 3% for a pharmacist or a dentist, respectively. Among smokers, over 40% would first ask a physician for advice on NRT; about 20% would first ask a pharmacist. About 42% and 8% of current smokers reported that they received advice in the past year from a physician and pharmacist, respectively. INTERPRETATION: Smokers are receptive to quit advice from physicians, but less likely to ask other health professionals. Few smokers received advice from pharmacists and dentists. Increasing the reach of quit advice requires both increased professional intervention and education of the public.
SN  - 0008-4263
U2  - PMID: 17985682.
UR  - http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106004192&site=ehost-live&scope=site
DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 105376269
T1  - Virtual reality skills training for health care professionals in alcohol screening and brief intervention.
AU  - Fleming M
AU  - Olsen D
AU  - Stathes H
AU  - Boteler L
AU  - Grossberg P
AU  - Pfeifer J
AU  - Schiro S
AU  - Banning J
AU  - Skochelak S
Y1  - 2009/07//2009 Jul-Aug
N1  - Accession Number: 105376269. Language: English. Entry Date: 20091023. Revision Date: 20150711. Publication Type: Journal Article; clinical trial; research. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 101256526. 
KW  - Alcoholism -- Diagnosis
KW  - Clinical Competence
KW  - Computer Simulation
KW  - Health Personnel
KW  - Health Screening -- Standards
KW  - User-Computer Interface
KW  - Adult
KW  - Clinical Trials
KW  - Female
KW  - Male
KW  - Middle Age
KW  - Wisconsin
KW  - Human
SP  - 387
EP  - 398 12p
JO  - Journal of the American Board of Family Medicine
JF  - Journal of the American Board of Family Medicine
JA  - J AM BOARD FAM MED
VL  - 22
IS  - 4
CY  - Lexington, Kentucky
PB  - American Board of Family Medicine
AB  - BACKGROUND: Educating physicians and other health care professionals about the identification and treatment of patients who drink more than recommended limits is an ongoing challenge. METHODS: An educational randomized controlled trial was conducted to test the ability of a stand-alone training simulation to improve the clinical skills of health care professionals in alcohol screening and intervention. The 'virtual reality simulation' combined video, voice recognition, and nonbranching logic to create an interactive environment that allowed trainees to encounter complex social cues and realistic interpersonal exchanges. The simulation included 707 questions and statements and 1207 simulated patient responses. RESULTS: A sample of 102 health care professionals (10 physicians; 30 physician assistants or nurse practitioners; 36 medical students; 26 pharmacy, physican assistant, or nurse practitioner students) were randomly assigned to a no training group (n = 51) or a computer-based virtual reality intervention (n = 51). Professionals in both groups had similar pretest standardized patient alcohol screening skill scores: 53.2 (experimental) vs 54.4 (controls), 52.2 vs 53.7 alcohol brief intervention skills, and 42.9 vs 43.5 alcohol referral skills. After repeated practice with the simulation there were significant increases in the scores of the experimental group at 6 months after randomization compared with the control group for the screening (67.7 vs 58.1; P < .001) and brief intervention (58.3 vs 51.6; P < .04) scenarios. CONCLUSIONS: The technology tested in this trial is the first virtual reality simulation to demonstrate an increase in the alcohol screening and brief intervention skills of health care professionals.
SN  - 1557-2625
AD  - Department of Family Medicine, University of Wisconsin, Madison, WI 53715, USA. mike.fleming@fammed.wisc.edu
U2  - PMID: 19587253.
DO  - 10.3122/jabfm.2009.04.080208
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 104622636
T1  - Willingness to use ADHD treatments: A mixed methods study of perceptions by adolescents, parents, health professionals and teachers.
AU  - Bussing, Regina
AU  - Koro-Ljungberg, Mirka
AU  - Noguchi, Kenji
AU  - Mason, Dana
AU  - Mayerson, Gillian
AU  - Garvan, Cynthia W.
Y1  - 2012/01//
N1  - Accession Number: 104622636. Language: English. Entry Date: 20120105. Revision Date: 20150711. Publication Type: Journal Article; research. Journal Subset: Allied Health; Biomedical; Continental Europe; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Special Interest: Pediatric Care; Social Work. NLM UID: 8303205. 
KW  - Attention Deficit Hyperactivity Disorder -- Drug Therapy -- In Adolescence
KW  - Parents -- Psychosocial Factors
KW  - Teachers -- Psychosocial Factors
KW  - Health Personnel -- Psychosocial Factors
KW  - Patients -- Psychosocial Factors
KW  - Human
KW  - Adolescence
KW  - Multimethod Studies
KW  - Multiple Regression
KW  - Male
KW  - Female
KW  - Socioeconomic Factors
KW  - Grounded Theory
KW  - Surveys
SP  - 92
EP  - 100 9p
JO  - Social Science & Medicine
JF  - Social Science & Medicine
JA  - SOC SCI MED
VL  - 74
IS  - 1
PB  - Pergamon Press - An Imprint of Elsevier Science
AB  - Abstract: Little is known about factors that influence willingness to engage in treatment for attention deficit/hyperactivity disorder (ADHD). From 2007 to 2008, in the context of a longitudinal study assessing ADHD detection and service use in the United States, we simultaneously elicited ADHD treatment perceptions from four stakeholder groups: adolescents, parents, health care professionals and teachers. We assessed their willingness to use ADHD interventions and views of potential undesirable effects of two pharmacological (short- and long-acting ADHD medications) and three psychosocial (ADHD education, behavior therapy, and counseling) treatments. In multiple regression analysis, willingness was found to be significantly related to respondent type (lower for adolescents than adults), feeling knowledgeable, and considering treatments acceptable and helpful, but not significantly associated with stigma/embarrassment, respondent race, gender and socioeconomic status. Because conceptual models of undesirable effects are underdeveloped, we used grounded theory method to analyze open-ended survey responses to the question: “What other undesirable effects are you concerned about?” We identified general negative treatment perceptions (dislike, burden, perceived ineffectiveness) and specific undesirable effect expectations (physiological and psychological side effects, stigma and future dependence on drugs or therapies) for pharmacological and psychosocial treatments. In summary, findings indicate significant discrepancies between teens’ and adults’ willingness to use common ADHD interventions, with low teen willingness for any treatments. Results highlight the need to develop better treatment engagement practices for adolescents with ADHD.
SN  - 0277-9536
AD  - Department of Psychiatry, University of Florida, Gainesville, FL, United States
AD  - School of Human Development and Organizational Studies in Education, University of Florida, Gainesville, FL, United States
AD  - Department of Psychology, University of Southern Mississippi Gulf Coast, Long Beach, MS, United States
U2  - PMID: 22133584.
DO  - 10.1016/j.socscimed.2011.10.009
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DP  - EBSCOhost
DB  - ccm
ER  - 

TY  - JOUR
ID  - 113758637
T1  - Woman focused smoking cessation programming: a qualitative study.
AU  - Minian, Nadia
AU  - Penner, Jessica
AU  - Voci, Sabrina
AU  - Selby, Peter
Y1  - 2016/03/12/
N1  - Accession Number: 113758637. Language: English. Entry Date: In Process. Revision Date: 20160321. Publication Type: Article. Journal Subset: Biomedical; Europe; UK & Ireland. NLM UID: 101088690. 
SP  - 1
EP  - 8 8p
JO  - BMC Women's Health
JF  - BMC Women's Health
JA  - BMC WOMENS HEALTH
VL  - 16
PB  - BioMed Central
AB  - Background: Several studies of smoking cessation programs in clinical settings have revealed poorer outcomes for women compared to men, including counselling alone or in combination with pharmacotherapy. The objective of the current study was to explore treatment and program structure needs and preferences among female clients in a specialized smoking cessation clinic in an academic mental health and addiction health science centre in order to inform program design so that it meets the needs of female clients.Methods: Four focus groups were conducted with current and former female clients (n = 23, mode age range = 50-59 years old, 56.5 % were still smoking and 43.5 % had quit) who had registered for outpatient smoking cessation treatment. Questions were designed to examine what aspects of the services were helpful and what changes they would like to see to better assist them and other women with quitting smoking. A thematic analysis of the raw data (audio recordings and notes taken during the focus groups) was conducted using a phenomenological theoretical framework.Results: Themes that emerged indicated that females trying to quit smoking are best supported if they have choice from a variety of services so that treatment can be individualized to meet their specific needs; psychosocial support is provided both one-one-one with health care professionals and by peers in support groups; free pharmacotherapy is available to eliminate financial barriers to use; women-specific educational topics and support groups are offered; the clinic is accessible with evening/weekend hours, options to attend a local clinic, and childcare availability; and communication about clinic services and operation are clear, readily available, and regularly updated.Conclusions: An ideal smoking cessation program for women includes a women's centred approach with sufficient variety and choice, free pharmacotherapy, non-judgmental support, accessible services and clear communication of program options and changes. Findings may suggest an actionable list of adaptations that can be adopted by other clinics providing smoking cessation services to women.
SN  - 1472-6874
AD  - Addictions Program, Centre for Addiction and Mental Health, 100 Stokes Street, Toronto, ON M6J 1H4, Canada
AD  - Department of Family and Community Medicine, University of Toronto, 500 University Avenue, Toronto, ON MG 17, Canada
AD  - Department of Psychiatry, University of Toronto, 250 College Street, 8 9 9 th floor, Toronto, ON MT 18, Canada
AD  - Dallas Lana School of Public Health, University of Toronto, 155 College Street, Toronto, ON MT 37, Canada
AD  - Ontario Tobacco Research Unit, 155 College Street, Toronto, ON MT 37, Canada
U2  - PMID: 26971306.
DO  - 10.1186/s12905-016-0298-2
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DP  - EBSCOhost
DB  - ccm
ER  -