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Depression and parental bonding: Cause, consequence, or genetic covariance?

dc.contributor.authorNeale, Michael C.en_US
dc.contributor.authorWalters, Ellenen_US
dc.contributor.authorHeath, Andrew C.en_US
dc.contributor.authorKessler, Ronald C.en_US
dc.contributor.authorPérusse, Danielen_US
dc.contributor.authorEaves, Lindon J.en_US
dc.contributor.authorKendler, Kenneth S.en_US
dc.date.accessioned2013-12-04T18:57:12Z
dc.date.available2013-12-04T18:57:12Z
dc.date.issued1994en_US
dc.identifier.citationNeale, Michael C.; Walters, Ellen; Heath, Andrew C.; Kessler, Ronald C.; Pérusse, Daniel ; Eaves, Lindon J.; Kendler, Kenneth S. (1994). "Depression and parental bonding: Cause, consequence, or genetic covariance?." Genetic Epidemiology 11(6): 503-522. <http://hdl.handle.net/2027.42/101796>en_US
dc.identifier.issn0741-0395en_US
dc.identifier.issn1098-2272en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/101796
dc.description.abstractIt is shown how information on the direction of causation between variables may be obtained from a cross‐sectional study of pairs of relatives. This method is applied to the study of the relationship between ratings of parents' rearing style and depression in their offspring. Adult female twins ascertained from a population‐based registry in Virginia completed the Center for Epidemiological Studies ‐ Depression Scale (CESD) and a 7‐item short form of the Parental Bonding Instrument (PBI) about each of their parents. Two dimensions of parental behavior, overprotectiveness and coldness, were analyzed jointly with depression data in both genetic factor and directional genetic models. Models that specify ratings of parents as a cause of depression in the offspring fit the data significantly better than models that specify depression as a cause of ratings of parents. A still better fit is obtained with models that specify common genetic variance to depression and ratings, though causal models with error variance perform almost as well. In general, ratings of fathers show more genetic and less shared environmental variance than ratings of mothers, which might arise from more consistent treatment of offspring by mothers than by fathers. No effect of children eliciting parental rearing style was detected with these data. The relative merits of instrumental variable, longitudinal, and family approaches to testing causal models are discussed. © 1994 Wiley‐Liss, Inc.en_US
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherLongitudinalen_US
dc.subject.otherInstrumental Variableen_US
dc.subject.otherDesignen_US
dc.subject.otherMethodologyen_US
dc.subject.otherStructural Equation Modelingen_US
dc.subject.otherMxen_US
dc.subject.otherParentsen_US
dc.subject.otherDepressionen_US
dc.subject.otherCESDen_US
dc.subject.otherPsychiatryen_US
dc.subject.otherGenesen_US
dc.subject.otherEnvironmenten_US
dc.subject.otherTwinsen_US
dc.subject.otherOverprotectivenessen_US
dc.subject.otherBondingen_US
dc.subject.otherColdnessen_US
dc.subject.otherParkeren_US
dc.subject.otherRatingsen_US
dc.subject.otherCausationen_US
dc.titleDepression and parental bonding: Cause, consequence, or genetic covariance?en_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbsecondlevelGeneticsen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumInstitute for Social Research, University of Michigan, Ann Arboren_US
dc.contributor.affiliationotherDepartment of Human Genetics, Medical College of Virginia, Richmonden_US
dc.contributor.affiliationotherDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Missourien_US
dc.contributor.affiliationotherDepartment of Psychiatry, Medical College of Virginia, Richmonden_US
dc.identifier.pmid7713392en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/101796/1/1370110607_ftp.pdf
dc.identifier.doi10.1002/gepi.1370110607en_US
dc.identifier.sourceGenetic Epidemiologyen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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