VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P 2 in yeast and mouse
dc.contributor.author | Jin, Natsuko | en_US |
dc.contributor.author | Chow, Clement Y. | en_US |
dc.contributor.author | Liu, Li | en_US |
dc.contributor.author | Zolov, Sergey N. | en_US |
dc.contributor.author | Bronson, Roderick | en_US |
dc.contributor.author | Davisson, Muriel | en_US |
dc.contributor.author | Petersen, Jason L. | en_US |
dc.contributor.author | Zhang, Yanling | en_US |
dc.contributor.author | Park, Sujin | en_US |
dc.contributor.author | Duex, Jason E. | en_US |
dc.contributor.author | Goldowitz, Daniel | en_US |
dc.contributor.author | Meisler, Miriam H. | en_US |
dc.contributor.author | Weisman, Lois S. | en_US |
dc.date.accessioned | 2014-01-08T20:34:20Z | |
dc.date.available | 2014-01-08T20:34:20Z | |
dc.date.issued | 2008-12-17 | en_US |
dc.identifier.citation | Jin, Natsuko; Chow, Clement Y; Liu, Li; Zolov, Sergey N; Bronson, Roderick; Davisson, Muriel; Petersen, Jason L; Zhang, Yanling; Park, Sujin; Duex, Jason E; Goldowitz, Daniel; Meisler, Miriam H; Weisman, Lois S (2008). "VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P 2 in yeast and mouse." The EMBO Journal 27(24): 3221-3234. <http://hdl.handle.net/2027.42/102059> | en_US |
dc.identifier.issn | 0261-4189 | en_US |
dc.identifier.issn | 1460-2075 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/102059 | |
dc.publisher | John Wiley & Sons, Ltd | en_US |
dc.subject.other | Saccharomyces Cerevisiae | en_US |
dc.subject.other | PIKfyve | en_US |
dc.subject.other | Phosphatidylinositol 3,5‐Bisphosphate | en_US |
dc.subject.other | Pale Tremor | en_US |
dc.title | VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P 2 in yeast and mouse | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.identifier.pmid | 19037259 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/102059/1/emboj2008248.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/102059/2/emboj2008248-sup-0002.pdf | |
dc.identifier.doi | 10.1038/emboj.2008.248 | en_US |
dc.identifier.source | The EMBO Journal | en_US |
dc.identifier.citedreference | Liu L, Geisert EE, Frankfurter A, Spano AJ, Jiang CX, Yue J, Dragatsis I, Goldowitz D ( 2007 ) A transgenic mouse class‐III beta tubulin reporter using yellow fluorescent protein. Genesis 45: 560 – 569 | en_US |
dc.identifier.citedreference | Bonangelino CJ, Nau JJ, Duex JE, Brinkman M, Wurmser AE, Gary JD, Emr SD, Weisman LS ( 2002 ) Osmotic stress‐induced increase of phosphatidylinositol 3,5‐bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p. J Cell Biol 156: 1015 – 1028 | en_US |
dc.identifier.citedreference | Botelho RJ, Efe JA, Teis D, Emr SD ( 2008 ) Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase. Mol Biol Cell 10: 4273 – 4286 | en_US |
dc.identifier.citedreference | Bronson R, Perides G, Sweet H, Ward‐Bailey PF, Davisson M ( 2003 ) Infantile gliosis (ingls) a new spontaneous mutation in the mouse. MGI Direct Data Submission http://mousemutant.jax.org/gliosis_paper.html | en_US |
dc.identifier.citedreference | Chook YM, Blobel G ( 1999 ) Structure of the nuclear transport complex karyopherin‐[beta]2‐Ran[dot]GppNHp. Nature 399: 230 – 237 | en_US |
dc.identifier.citedreference | Chow CY, Zhang Y, Dowling JJ, Jin N, Adamska M, Shiga K, Szigeti K, Shy ME, Li J, Zhang X, Lupski JR, Weisman LS, Meisler MH ( 2007 ) Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J. Nature 448: 68 – 72 | en_US |
dc.identifier.citedreference | Cingolani G, Petosa C, Weis K, Muller CW ( 1999 ) Structure of importin‐[beta] bound to the IBB domain of importin‐[alpha]. Nature 399: 221 – 229 | en_US |
dc.identifier.citedreference | Di Paolo G, De Camilli P ( 2006 ) Phosphoinositides in cell regulation and membrane dynamics. Nature 443: 651 – 657 | en_US |
dc.identifier.citedreference | Dove SK, McEwen RK, Mayes A, Hughes DC, Beggs JD, Michell RH ( 2002 ) Vac14 controls PtdIns(3,5)P(2) synthesis and Fab1‐dependent protein trafficking to the multivesicular body. Curr Biol 12: 885 – 893 | en_US |
dc.identifier.citedreference | Dove SK, Piper RC, McEwen RK, Yu JW, King MC, Hughes DC, Thuring J, Holmes AB, Cooke FT, Michell RH, Parker PJ, Lemmon MA ( 2004 ) Svp1p defines a family of phosphatidylinositol 3,5‐bisphosphate effectors. EMBO J 23: 1922 – 1933 | en_US |
dc.identifier.citedreference | Duex JE, Nau JJ, Kauffman EJ, Weisman LS ( 2006a ) Phosphoinositide 5‐phosphatase Fig 4p is required for both acute rise and subsequent fall in stress‐induced phosphatidylinositol 3,5‐bisphosphate levels. Eukaryot Cell 5: 723 – 731 | en_US |
dc.identifier.citedreference | Duex JE, Tang F, Weisman LS ( 2006b ) The Vac14p–Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnover. J Cell Biol 172: 693 – 704 | en_US |
dc.identifier.citedreference | Efe JA, Botelho RJ, Emr SD ( 2007 ) Atg18 regulates organelle morphology and Fab1 kinase activity independent of its membrane recruitment by phosphatidylinositol 3,5‐bisphosphate. Mol Biol Cell 11: 4232 – 4244 | en_US |
dc.identifier.citedreference | Flanigan K, Gardner K, Alderson K, Galster B, Otterud B, Leppert MF, Kaplan C, Ptacek LJ ( 1996 ) Autosomal dominant spinocerebellar ataxia with sensory axonal neuropathy (SCA4): clinical description and genetic localization to chromosome 16q22.1. Am J Hum Genet 59: 392 – 399 | en_US |
dc.identifier.citedreference | Gary JD, Sato TK, Stefan CJ, Bonangelino CJ, Weisman LS, Emr SD ( 2002 ) Regulation of Fab1 phosphatidylinositol 3‐phosphate 5‐kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member. Mol Biol Cell 13: 1238 – 1251 | en_US |
dc.identifier.citedreference | Gary JD, Wurmser AE, Bonangelino CJ, Weisman LS, Emr SD ( 1998 ) Fab1p is essential for PtdIns(3)P 5‐kinase activity and the maintenance of vacuolar size and membrane homeostasis. J Cell Biol 143: 65 – 79 | en_US |
dc.identifier.citedreference | Groves MR, Hanlon N, Turowski P, Hemmings BA, Barford D ( 1999 ) The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs. Cell 96: 99 – 110 | en_US |
dc.identifier.citedreference | Ikonomov OC, Sbrissa D, Shisheva A ( 2006 ) Localized PtdIns 3,5‐P2 synthesis to regulate early endosome dynamics and fusion. Am J Physiol Cell Physiol 291: C393 – C404 | en_US |
dc.identifier.citedreference | James P, Halladay J, Craig EA ( 1996 ) Genomic libraries and a host strain designed for highly efficient two‐hybrid selection in yeast. Genetics 144: 1425 – 1436 | en_US |
dc.identifier.citedreference | Matteis MAD, Godi A ( 2004 ) PI‐loting membrane traffic. Nat Cell Biol 6: 487 – 492 | en_US |
dc.identifier.citedreference | Perry J, Kleckner N ( 2003 ) The ATRs, ATMs, and TORs are giant HEAT repeat proteins. Cell 112: 151 – 155 | en_US |
dc.identifier.citedreference | Rudge SA, Anderson DM, Emr SD ( 2004 ) Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole‐associated Vac14‐Fig4 complex, a PtdIns(3,5)P2‐specific phosphatase. Mol Biol Cell 15: 24 – 36 | en_US |
dc.identifier.citedreference | Rutherford AC, Traer C, Wassmer T, Pattni K, Bujny MV, Carlton JG, Stenmark H, Cullen PJ ( 2006 ) The mammalian phosphatidylinositol 3‐phosphate 5‐kinase (PIKfyve) regulates endosome‐to‐TGN retrograde transport. J Cell Sci 119: 3944 – 3957 | en_US |
dc.identifier.citedreference | Sbrissa D, Ikonomov OC, Fu Z, Ijuin T, Gruenberg J, Takenawa T, Shisheva A ( 2007 ) Core protein machinery for mammalian phosphatidylinositol 3,5‐bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve‐PIKfyve complex. J Biol Chem 282: 23878 – 23891 | en_US |
dc.identifier.citedreference | Volpicelli‐Daley L, De Camilli P ( 2007 ) Phosphoinositides’ link to neurodegeneration. Nat Med 13: 784 – 786 | en_US |
dc.identifier.citedreference | Xing Y, Xu Y, Chen Y, Jeffrey PD, Chao Y, Lin Z, Li Z, Strack S, Stock JB, Shi Y ( 2006 ) Structure of protein phosphatase 2A core enzyme bound to tumor‐inducing toxins. Cell 127: 341 – 353 | en_US |
dc.identifier.citedreference | Yamamoto A, DeWald DB, Boronenkov IV, Anderson RA, Emr SD, Koshland D ( 1995 ) Novel PI(4)P 5‐kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast. Mol Biol Cell 6: 525 – 539 | en_US |
dc.identifier.citedreference | Zhang X, Chow CY, Sahenk Z, Shy ME, Meisler MH, Li J ( 2008 ) Mutation of FIG4 causes a rapidly progressive, asymmetric neuronal degeneration. Brain 131: 1990 – 2001 | en_US |
dc.identifier.citedreference | Zhang Y, Zolov SN, Chow CY, Slutsky SG, Richardson SC, Piper RC, Yang B, Nau JJ, Westrick RJ, Morrison SJ, Meisler MH, Weisman LS ( 2007 ) Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5‐bisphosphate, results in neurodegeneration in mice. Proc Natl Acad Sci USA 104: 17518 – 17523 | en_US |
dc.identifier.citedreference | Andrade MA, Ponting CP, Gibson TJ, Bork P ( 2000 ) Homology‐based method for identification of protein repeats using statistical significance estimates. J Mol Biol 298: 521 – 537 | en_US |
dc.identifier.citedreference | Behnia R, Munro S ( 2005 ) Organelle identity and the signposts for membrane traffic. Nature 438: 597 – 604 | en_US |
dc.identifier.citedreference | Bolis A, Zordan P, Coviello S, Bolino A ( 2007 ) Myotubularin‐related (MTMR) phospholipid phosphatase proteins in the peripheral nervous system. Mol Neurobiol 35: 308 – 316 | en_US |
dc.identifier.citedreference | Bonangelino CJ, Catlett NL, Weisman LS ( 1997 ) Vac7p, a novel vacuolar protein, is required for normal vacuole inheritance and morphology. Mol Cell Biol 17: 6847 – 6858 | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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