Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization
dc.contributor.author | Moeller, Marcus J | en_US |
dc.contributor.author | Soofi, Abdulsalam | en_US |
dc.contributor.author | Braun, Gerald S | en_US |
dc.contributor.author | Li, Xiaodong | en_US |
dc.contributor.author | Watzl, Carsten | en_US |
dc.contributor.author | Kriz, Wilhelm | en_US |
dc.contributor.author | Holzman, Lawrence B | en_US |
dc.date.accessioned | 2014-01-08T20:34:20Z | |
dc.date.available | 2014-01-08T20:34:20Z | |
dc.date.issued | 2004-09-29 | en_US |
dc.identifier.citation | Moeller, Marcus J; Soofi, Abdulsalam; Braun, Gerald S; Li, Xiaodong; Watzl, Carsten; Kriz, Wilhelm; Holzman, Lawrence B (2004). "Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization." The EMBO Journal 23(19): 3769-3779. <http://hdl.handle.net/2027.42/102060> | en_US |
dc.identifier.issn | 0261-4189 | en_US |
dc.identifier.issn | 1460-2075 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/102060 | |
dc.publisher | John Wiley & Sons, Ltd | en_US |
dc.subject.other | Actin Dynamics | en_US |
dc.subject.other | FAT1 | en_US |
dc.subject.other | Planar Cell Polarity | en_US |
dc.subject.other | VASP | en_US |
dc.subject.other | Cellular Migration | en_US |
dc.title | Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.identifier.pmid | 15343270 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/102060/1/emboj7600380.pdf | |
dc.identifier.doi | 10.1038/sj.emboj.7600380 | en_US |
dc.identifier.source | The EMBO Journal | en_US |
dc.identifier.citedreference | Rawls AS, Guinto JB, Wolff T ( 2002 ) The cadherins fat and dachsous regulate dorsal/ventral signaling in the Drosophila eye. Curr Biol 12: 1021 – 1026 | en_US |
dc.identifier.citedreference | Hinz B, Alt W, Johnen C, Herzog V, Kaiser HW ( 1999 ) Quantifying lamella dynamics of cultured cells by SACED, a new computer‐assisted motion analysis. Exp Cell Res 251: 234 – 243 | en_US |
dc.identifier.citedreference | Inoue T, Yaoita E, Kurihara H, Shimizu F, Sakai T, Kobayashi T, Ohshiro K, Kawachi H, Okada H, Suzuki H, Kihara I, Yamamoto T ( 2001 ) FAT is a component of glomerular slit diaphragms. Kidney Int 59: 1003 – 1012 | en_US |
dc.identifier.citedreference | Kaltschmidt JA, Lawrence N, Morel V, Balayo T, Fernandez BG, Pelissier A, Jacinto A, Martinez Arias A ( 2002 ) Planar polarity and actin dynamics in the epidermis of Drosophila. Nat Cell Biol 4: 937 – 944 | en_US |
dc.identifier.citedreference | Kamberov E, Makarova O, Roh M, Liu A, Karnak D, Straight S, Margolis B ( 2000 ) Molecular cloning and characterization of Pals, proteins associated with mLin‐7. J Biol Chem 275: 11425 – 11431 | en_US |
dc.identifier.citedreference | Ma D, Yang CH, McNeill H, Simon MA, Axelrod JD ( 2003 ) Fidelity in planar cell polarity signalling. Nature 421: 543 – 547 | en_US |
dc.identifier.citedreference | Mahoney PA, Weber U, Onofrechuk P, Biessmann H, Bryantand PJ, Goodman CS ( 1991 ) The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily. Cell 67: 853 – 868 | en_US |
dc.identifier.citedreference | Makarova O, Kamberov E, Margolis B ( 2000 ) Generation of deletion and point mutations with one primer in a single cloning step. Biotechniques 29: 970 – 972 | en_US |
dc.identifier.citedreference | Mitsui K, Nakajima D, Ohara O, Nakayama M ( 2002 ) Mammalian fat3: a large protein that contains multiple cadherin and EGF‐like motifs. Biochem Biophys Res Commun 290: 1260 – 1266 | en_US |
dc.identifier.citedreference | Moeller MJ, Sanden SK, Soofi A, Wiggins RC, Holzman LB ( 2002 ) Two gene fragments that direct podocyte‐specific expression in transgenic mice. J Am Soc Nephrol 13: 1561 – 1567 | en_US |
dc.identifier.citedreference | Niebuhr K, Ebel F, Frank R, Reinhard M, Domann E, Carl UD, Walter U, Gertler FB, Wehland J, Chakraborty T ( 1997 ) A novel proline‐rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family. EMBO J 16: 5433 – 5544 | en_US |
dc.identifier.citedreference | Nihalani D, Meyer D, Pajni S, Holzman LB ( 2001 ) Mixed lineage kinase‐dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module components. EMBO J 20: 3447 – 3458 | en_US |
dc.identifier.citedreference | Nobes CD, Hall A ( 1999 ) Rho GTPases control polarity, protrusion, and adhesion during cell movement. J Cell Biol 144: 1235 – 1244 | en_US |
dc.identifier.citedreference | Paul CP, Good PD, Winer I, Engelke DR ( 2002 ) Effective expression of small interfering RNA in human cells. Nat Biotechnol 20: 505 – 508 | en_US |
dc.identifier.citedreference | Pistor S, Chakraborty T, Niebuhr K, Domann E, Wehland J ( 1994 ) The ActA protein of Listeria monocytogenes acts as a nucleator inducing reorganization of the actin cytoskeleton. EMBO J 13: 758 – 763 | en_US |
dc.identifier.citedreference | Ponassi M, Jacques TS, Ciani L, ffrench Constant C ( 1999 ) Expression of the rat homologue of the Drosophila fat tumour suppressor gene. Mech Dev 80: 207 – 212 | en_US |
dc.identifier.citedreference | Rottner K, Behrendt B, Small JV, Wehland J ( 1999 ) VASP dynamics during lamellipodia protrusion. Nat Cell Biol 1: 321 – 322 | en_US |
dc.identifier.citedreference | Rubinson DA, Dillon CP, Kwiatkowski AV, Sievers C, Yang L, Kopinja J, Rooney DL, Ihrig MM, McManus MT, Gertler FB, Scott ML, Van Parijs L ( 2003 ) A lentivirus‐based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet 33: 401 – 406 | en_US |
dc.identifier.citedreference | Samarin S, Romero S, Kocks C, Didry D, Pantaloni D, Carlier MF ( 2003 ) How VASP enhances actin‐based motility. J Cell Biol 163: 131 – 142 | en_US |
dc.identifier.citedreference | Tanoue T, Takeichi M ( 2004 ) Mammalian Fat1 cadherin regulates actin dynamics and cell–cell contact. J Cell Biol 165: 517 – 528 | en_US |
dc.identifier.citedreference | Vasioukhin V, Bauer C, Yin M, Fuchs E ( 2000 ) Directed actin polymerization is the driving force for epithelial cell–cell adhesion. Cell 100: 209 – 219 | en_US |
dc.identifier.citedreference | Welch MD, DePace AH, Verma S, Iwamatsu A, Mitchison TJ ( 1997 ) The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly. J Cell Biol 138: 375 – 384 | en_US |
dc.identifier.citedreference | Wu Q, Maniatis T ( 2000 ) Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes. Proc Natl Acad Sci USA 97: 3124 – 3129 | en_US |
dc.identifier.citedreference | Yang CH, Axelrod JD, Simon MA ( 2002 ) Regulation of Frizzled by fat‐like cadherins during planar polarity signaling in the Drosophila compound eye. Cell 108: 675 – 688 | en_US |
dc.identifier.citedreference | Bear JE, Svitkina TM, Krause M, Schafer DA, Loureiro JJ, Strasser GA, Maly IV, Chaga OY, Cooper JA, Borisy GG, Gertler FB ( 2002 ) Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility. Cell 109: 509 – 521 | en_US |
dc.identifier.citedreference | Bershadsky AD, Futerman AH ( 1994 ) Disruption of the Golgi apparatus by brefeldin A blocks cell polarization and inhibits directed cell migration. Proc Natl Acad Sci USA 91: 5686 – 5689 | en_US |
dc.identifier.citedreference | Ciani L, Patel A, Allen ND, ffrench‐Constant C ( 2003 ) Mice lacking the giant protocadherin mFAT1 exhibit renal slit junction abnormalities and a partially penetrant cyclopia and anophthalmia phenotype. Mol Cell Biol 23: 3575 – 3582 | en_US |
dc.identifier.citedreference | Cox B, Hadjantonakis AK, Collins JE, Megee AI ( 2000 ) Cloning and expression throughout mouse development of mfat1, a homologue of the Drosophila tumour suppressor gene fat. Dev Dyn 217: 233 – 240 | en_US |
dc.identifier.citedreference | Dunne J, Hanby AM, Poulsom R, Jones TA, Sheer D, Chin WG, Da SM, Zhao Q, Beverley PC, Owen MJ ( 1995 ) Molecular cloning and tissue expression of FAT, the human homologue of the Drosophila fat gene that is located on chromosome 4q34–q35 and encodes a putative adhesion molecule. Genomics 30: 207 – 223 | en_US |
dc.identifier.citedreference | Fradelizi J, Noireaux V, Plastino J, Menichi B, Louvard D, Sykes C, Golsteyn RM, Friederich E ( 2001 ) ActA and human zyxin harbour Arp2/3‐independent actin‐polymerization activity. Nat Cell Biol 3: 699 – 707 | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.