View Item 

Show simple item record

Novel TCF‐binding sites specify transcriptional repression by Wnt signalling
dc.contributor.authorBlauwkamp, Timothy Aen_US
dc.contributor.authorChang, Mikyung Ven_US
dc.contributor.authorCadigan, Ken Men_US
dc.date.accessioned2014-01-08T20:34:35Z
dc.date.available2014-01-08T20:34:35Z
dc.date.issued2008-05-21en_US
dc.identifier.citationBlauwkamp, Timothy A; Chang, Mikyung V; Cadigan, Ken M (2008). "Novel TCF‐binding sites specify transcriptional repression by Wnt signalling." The EMBO Journal 27(10): 1436-1446. <http://hdl.handle.net/2027.42/102103>en_US
dc.identifier.issn0261-4189en_US
dc.identifier.issn1460-2075en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/102103
dc.publisherJohn Wiley & Sons, Ltden_US
dc.subject.otherTCFen_US
dc.subject.otherWinglessen_US
dc.subject.otherβ‐Cateninen_US
dc.subject.otherArmadilloen_US
dc.subject.otherAllostericen_US
dc.titleNovel TCF‐binding sites specify transcriptional repression by Wnt signallingen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.identifier.pmid18418383en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/102103/1/emboj200880-sup-0001.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/102103/2/emboj200880.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/102103/3/emboj200880-sup-0002.pdf
dc.identifier.doi10.1038/emboj.2008.80en_US
dc.identifier.sourceThe EMBO Journalen_US
dc.identifier.citedreferencePiepenburg O, Vorbruggen G, Jackle H ( 2000 ) Drosophila segment borders result from unilateral repression of hedgehog activity by wingless signaling. Mol Cell 6: 203 – 209en_US
dc.identifier.citedreferencePai LM, Orsulic S, Bejsovec A, Peifer M ( 1997 ) Negative regulation of Armadillo, a Wingless effector in Drosophila. Development 124: 2255 – 2266en_US
dc.identifier.citedreferenceParker DS, Blauwkamp T, Cadigan KM ( 2007 ) Wnt/β‐catenin‐mediated transcriptional regulation. In Wnt Signaling in Embryonic Development, Sokol S (ed), Advances in Developmental Biology, Wassarman PM (ed), Vol. 17, pp. 1 – 61. San Diego: Elsevieren_US
dc.identifier.citedreferencePayre F, Vincent A, Carreno S ( 1999 ) ovo/svb integrates Wingless and DER pathways to control epidermis differentiation. Nature 400: 271 – 275en_US
dc.identifier.citedreferencePyrowolakis G, Hartmann B, Muller B, Basler K, Affolter M ( 2004 ) A simple molecular complex mediates widespread BMP‐induced repression during Drosophila development. Dev Cell 7: 229 – 240en_US
dc.identifier.citedreferenceRiggleman B, Schedl P, Wieschaus E ( 1990 ) Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless. Cell 63: 549 – 560en_US
dc.identifier.citedreferenceSaatcioglu F, Deng T, Karin M ( 1993 ) A novel cis element mediating ligand‐independent activation by c‐ErbA: implications for hormonal regulation. Cell 75: 1095 – 1105en_US
dc.identifier.citedreferenceScherfer C, Karlsson C, Loseva O, Bidla G, Goto A, Havemann J, Dushay MS, Theopold U ( 2004 ) Isolation and characterization of hemolymph clotting factors in Drosophila melanogaster by a pullout method. Curr Biol 14: 625 – 629en_US
dc.identifier.citedreferenceScully KM, Jacobson EM, Jepsen K, Lunyak V, Viadiu H, Carriere C, Rose DW, Hooshmand F, Aggarwal AK, Rosenfeld MG ( 2000 ) Allosteric effects of Pit‐1 DNA sites on long‐term repression in cell type specification. Science 290: 1127 – 1131en_US
dc.identifier.citedreferenceStadeli R, Basler K ( 2005 ) Dissecting nuclear Wingless signalling: recruitment of the transcriptional co‐activator Pygopus by a chain of adaptor proteins. Mech Dev 122: 1171 – 1182en_US
dc.identifier.citedreferenceStadeli R, Hoffmans R, Basler K ( 2006 ) Transcription under the control of nuclear Arm/beta‐catenin. Curr Biol 16: R378 – R385en_US
dc.identifier.citedreferenceTheisen H, Syed A, Nguyen BT, Lukacsovich T, Purcell J, Srivastava GP, Iron D, Gaudenz K, Nie Q, Wan FY, Waterman ML, Marsh JL ( 2007 ) Wingless directly represses DPP morphogen expression via an armadillo/TCF/Brinker complex. PLoS ONE 2007: e142en_US
dc.identifier.citedreferenceTomancak P, Beaton A, Weiszmann R, Kwan E, Shu S, Lewis SE, Richards S, Ashburner M, Hartenstein V, Celniker SE, Rubin GM ( 2002 ) Systematic determination of patterns of gene expression during Drosophila embryogenesis. Genome Biol 3: RESEARCH0088en_US
dc.identifier.citedreferencevan de Wetering M, Cavallo R, Dooijes D, van Beest M, van Es J, Loureiro J, Ypma A, Hursh D, Jones T, Bejsovec A, Peifer M, Mortin M, Clevers H ( 1997 ) Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF. Cell 88: 789 – 799en_US
dc.identifier.citedreferencevan de Wetering M, Sancho E, Verweij C, de Lau W, Oving I, Hurlstone A, van der Horn K, Batlle E, Coudreuse D, Haramis AP, Tjon‐Pon‐Fong M, Moerer P, van den Born M, Soete G, Pals S, Eilers M, Medema R, Clevers H ( 2002 ) The beta‐catenin/TCF‐4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 111: 241 – 250en_US
dc.identifier.citedreferenceWebster NJ, Green S, Jin JR, Chambon P ( 1988 ) The hormone‐binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function. Cell 54: 199 – 207en_US
dc.identifier.citedreferenceWillert J, Epping M, Pollack JR, Brown PO, Nusse R ( 2002 ) A transcriptional response to Wnt protein in human embryonic carcinoma cells. BMC Dev Biol 2: 8en_US
dc.identifier.citedreferenceYindeeyoungyeon W, Schell MA ( 2000 ) Footprinting with an automated capillary DNA sequencer. Biotechniques 29: 1034 – 1038en_US
dc.identifier.citedreferenceZachariou A, Tenev T, Goyal L, Agapite J, Steller H, Meier P ( 2003 ) IAP‐antagonists exhibit non‐redundant modes of action through differential DIAP1 binding. EMBO J 22: 6642 – 6652en_US
dc.identifier.citedreferenceZettervall CJ, Anderl I, Williams MJ, Palmer R, Kurucz E, Ando I, Hultmark D ( 2004 ) A directed screen for genes involved in Drosophila blood cell activation. Proc Natl Acad Sci USA 101: 14192 – 14197en_US
dc.identifier.citedreferenceAtcha FA, Syed A, Wu B, Hoverter NP, Yokoyama NN, Ting JH, Munguia JE, Mangalam HJ, Marsh JL, Waterman ML ( 2007 ) A unique DNA binding domain converts T‐cell factors into strong Wnt effectors. Mol Cell Biol 27: 8352 – 8363en_US
dc.identifier.citedreferenceAlfonso TB, Jones BW ( 2002 ) gcm2 promotes glial cell differentiation and is required with glial cells missing for macrophage development in Drosophila. Dev Biol 248: 369 – 383en_US
dc.identifier.citedreferenceBarolo S ( 2006 ) Transgenic Wnt/TCF pathway reporters: all you need is Lef? Oncogene 25: 7505 – 7511en_US
dc.identifier.citedreferenceBarolo S, Posakony JW ( 2002 ) Three habits of highly effective signaling pathways: principles of transcriptional control by developmental cell signaling. Genes Dev 16: 1167 – 1181en_US
dc.identifier.citedreferenceBrand AH, Perrimon N ( 1993 ) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401 – 415en_US
dc.identifier.citedreferenceCadigan KM ( 2002 ) Regulating morphogen gradients in the Drosophila wing. Semin Cell Dev Biol 13: 83 – 90en_US
dc.identifier.citedreferenceCadigan KM, Fish MP, Rulifson EJ, Nusse R ( 1998 ) Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing. Cell 93: 767 – 777en_US
dc.identifier.citedreferenceCadigan KM, Nusse R ( 1997 ) Wnt signaling: a common theme in animal development. Genes Dev 11: 3286 – 3305en_US
dc.identifier.citedreferenceCavallo RA, Cox RT, Moline MM, Roose J, Polevoy GA, Clevers H, Peifer M, Bejsovec A ( 1998 ) Drosophila Tcf and Groucho interact to repress Wingless signalling activity. Nature 395: 604 – 608en_US
dc.identifier.citedreferenceDaniels DL, Eklof Spink K, Weis WI ( 2001 ) Beta‐catenin: molecular plasticity and drug design. Trends Biochem Sci 26: 672 – 678en_US
dc.identifier.citedreferenceDaniels DL, Weis WI ( 2002 ) ICAT inhibits beta‐catenin binding to Tcf/Lef‐family transcription factors and the general coactivator p300 using independent structural modules. Mol Cell 10: 573 – 584en_US
dc.identifier.citedreferenceFang M, Li J, Blauwkamp T, Bhambhani C, Campbell N, Cadigan KM ( 2006 ) C‐Terminal‐binding protein directly activates and represses Wnt transcriptional targets in Drosophila. EMBO J 25: 2735 – 2745en_US
dc.identifier.citedreferenceFogerty FJ, Fessler LI, Bunch TA, Yaron Y, Parker CG, Nelson RE, Brower DL, Gullberg D, Fessler JH ( 1994 ) Tiggrin, a novel Drosophila extracellular matrix protein that functions as a ligand for Drosophila alpha PS2 beta PS integrins. Development 120: 1747 – 1758en_US
dc.identifier.citedreferenceGiese K, Amsterdam A, Grosschedl R ( 1991 ) DNA‐binding properties of the HMG domain of the lymphoid‐specific transcriptional regulator LEF‐1. Genes Dev 5: 2567 – 2578en_US
dc.identifier.citedreferenceGlass CK, Rosenfeld MG ( 2000 ) The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev 14: 121 – 141en_US
dc.identifier.citedreferenceGoto A, Kumagai T, Kumagai C, Hirose J, Narita H, Mori H, Kadowaki T, Beck K, Kitagawa Y ( 2001 ) A Drosophila haemocyte‐specific protein, hemolectin, similar to human von Willebrand factor. Biochem J 359: 99 – 108en_US
dc.identifier.citedreferenceHallikas O, Palin K, Sinjushina N, Rautiainen R, Partanen J, Ukkonen E, Taipale J ( 2006 ) Genome‐wide prediction of mammalian enhancers based on analysis of transcription‐factor binding affinity. Cell 124: 47 – 59en_US
dc.identifier.citedreferenceHoffmans R, Basler K ( 2004 ) Identification and in vivo role of the Armadillo–Legless interaction. Development 131: 4393 – 4400en_US
dc.identifier.citedreferenceHsu SC, Galceran J, Grosschedl R ( 1998 ) Modulation of transcriptional regulation by LEF‐1 in response to Wnt‐1 signaling and association with beta‐catenin. Mol Cell Biol 18: 4807 – 4818en_US
dc.identifier.citedreferenceIwaki T, Figuera M, Ploplis VA, Castellino FJ ( 2003 ) Rapid selection of Drosophila S2 cells with the puromycin resistance gene. Biotechniques 35: 482 – 484en_US
dc.identifier.citedreferenceJamora C, DasGupta R, Kocieniewski P, Fuchs E ( 2003 ) Links between signal transduction, transcription and adhesion in epithelial bud development. Nature 422: 317 – 322en_US
dc.identifier.citedreferenceJung HC, Kim K ( 2005 ) Identification of MYCBP as a beta‐catenin/LEF‐1 target using DNA microarray analysis. Life Sci 77: 1249 – 1262en_US
dc.identifier.citedreferenceKent WJ, Sugnet CW, Furey TS, Roskin KM, Pringle TH, Zahler AM, Haussler D ( 2002 ) The human genome browser at UCSC. Genome Res 12: 996 – 1006en_US
dc.identifier.citedreferenceKikuchi A, Kishida S, Yamamoto H ( 2006 ) Regulation of Wnt signaling by protein–protein interaction and post‐translational modifications. Exp Mol Med 38: 1 – 10en_US
dc.identifier.citedreferenceKnirr S, Frasch M ( 2001 ) Molecular integration of inductive and mesoderm‐intrinsic inputs governs even‐skipped enhancer activity in a subset of pericardial and dorsal muscle progenitors. Dev Biol 238: 13 – 26en_US
dc.identifier.citedreferenceLazar MA ( 2003 ) Thyroid hormone action: a binding contract. J Clin Invest 112: 497 – 499en_US
dc.identifier.citedreferenceLee HH, Frasch M ( 2000 ) Wingless effects mesoderm patterning and ectoderm segmentation events via induction of its downstream target sloppy paired. Development 127: 5497 – 5508en_US
dc.identifier.citedreferenceLefstin JA, Yamamoto KR ( 1998 ) Allosteric effects of DNA on transcriptional regulators. Nature 392: 885 – 888en_US
dc.identifier.citedreferenceLeung TH, Hoffmann A, Baltimore D ( 2004 ) One nucleotide in a kappaB site can determine cofactor specificity for NF‐kappaB dimers. Cell 118: 453 – 464en_US
dc.identifier.citedreferenceLi J, Sutter C, Parker DS, Blauwkamp T, Fang M, Cadigan KM ( 2007 ) CBP/p300 are bimodal regulators of Wnt signaling. EMBO J 26: 2284 – 2294en_US
dc.identifier.citedreferenceLin HV, Rogulja A, Cadigan KM ( 2004 ) Wingless eliminates ommatidia from the edge of the developing eye through activation of apoptosis. Development 131: 2409 – 2418en_US
dc.identifier.citedreferenceLogan CY, Nusse R ( 2004 ) The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 20: 781 – 810en_US
dc.identifier.citedreferenceLuecke HF, Yamamoto KR ( 2005 ) The glucocorticoid receptor blocks P‐TEFb recruitment by NFkappaB to effect promoter‐specific transcriptional repression. Genes Dev 19: 1116 – 1127en_US
dc.identifier.citedreferenceLuque T, O‧Reilly DR ( 2002 ) Functional and phylogenetic analyses of a putative Drosophila melanogaster UDP‐glycosyltransferase gene. Insect Biochem Mol Biol 32: 1597 – 1604en_US
dc.identifier.citedreferenceMosimann C, Hausmann G, Basler K ( 2006 ) Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta‐catenin/Armadillo. Cell 125: 327 – 341en_US
dc.identifier.citedreferenceNaishiro Y, Yamada T, Idogawa M, Honda K, Takada M, Kondo T, Imai K, Hirohashi S ( 2005 ) Morphological and transcriptional responses of untransformed intestinal epithelial cells to an oncogenic beta‐catenin protein. Oncogene 24: 3141 – 3153en_US
dc.identifier.citedreferenceNelson RE, Fessler LI, Takagi Y, Blumberg B, Keene DR, Olson PF, Parker CG, Fessler JH ( 1994 ) Peroxidasin: a novel enzyme‐matrix protein of Drosophila development. EMBO J 13: 3438 – 3447en_US
dc.identifier.citedreferenceNygard M, Becker N, Demeneix B, Pettersson K, Bondesson M ( 2006 ) Thyroid hormone‐mediated negative transcriptional regulation of Necdin expression. J Mol Endocrinol 36: 517 – 530en_US
dc.identifier.citedreferenceNygard M, Wahlstrom GM, Gustafsson MV, Tokumoto YM, Bondesson M ( 2003 ) Hormone‐dependent repression of the E2F‐1 gene by thyroid hormone receptors. Mol Endocrinol 17: 79 – 92en_US
dc.identifier.citedreferenceOgawa H, Ishiguro K, Gaubatz S, Livingston DM, Nakatani Y ( 2002 ) A complex with chromatin modifiers that occupies E2F‐ and Myc‐responsive genes in G0 cells. Science 296: 1132 – 1136en_US
dc.identifier.citedreferenceOlofsson B, Page DT ( 2005 ) Condensation of the central nervous system in embryonic Drosophila is inhibited by blocking hemocyte migration or neural activity. Dev Biol 279: 233 – 243en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Name:
emboj200880-sup-0001.pdf
Size:
44.63KB
Format:
PDF
View/Open
Name:
emboj200880.pdf
Size:
327.1KB
Format:
PDF
View/Open
Name:
emboj200880-sup-0002.pdf
Size:
87.04KB
Format:
PDF
View/Open

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.