harakiri , a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival‐promoting proteins Bcl‐2 and Bcl‐X L
dc.contributor.author | Inohara, Naohiro | en_US |
dc.contributor.author | Ding, Liyun | en_US |
dc.contributor.author | Chen, Shu | en_US |
dc.contributor.author | Núñez, Gabriel | en_US |
dc.date.accessioned | 2014-01-08T20:34:41Z | |
dc.date.available | 2014-01-08T20:34:41Z | |
dc.date.issued | 1997-04-01 | en_US |
dc.identifier.citation | Inohara, Naohiro; Ding, Liyun; Chen, Shu; Núñez, Gabriel (1997). " harakiri , a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survivalâ promoting proteins Bclâ 2 and Bclâ X L ." The EMBO Journal 16(7): 1686-1694. <http://hdl.handle.net/2027.42/102121> | en_US |
dc.identifier.issn | 0261-4189 | en_US |
dc.identifier.issn | 1460-2075 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/102121 | |
dc.publisher | John Wiley & Sons, Ltd | en_US |
dc.subject.other | Hrk | en_US |
dc.subject.other | Bcl‐2 Family | en_US |
dc.subject.other | Apoptosis | en_US |
dc.subject.other | Programmed Cell Death | en_US |
dc.title | harakiri , a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival‐promoting proteins Bcl‐2 and Bcl‐X L | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.identifier.pmid | 9130713 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/102121/1/emboj7590158.pdf | |
dc.identifier.doi | 10.1093/emboj/16.7.1686 | en_US |
dc.identifier.source | The EMBO Journal | en_US |
dc.identifier.citedreference | Swaroop A and Xu J ( 1993 ) cDNA libraries from human tissues and cell lines. Cytogenet Cell Genet, 64, 292 – 294. | en_US |
dc.identifier.citedreference | Merino R, Grillot DA, Simonian PL, Muthukkumar S, Fanslow WC, Bondada S and Núñez G ( 1995 ) Modulation of anti‐IgM‐induced B cell apoptosis by Bcl‐X L and CD40 in WEHI‐231 cells: dissociation from cell cycle arrest and dependence of the antibody–IgM receptor interaction. J Immunol, 155, 3830 – 3838. | en_US |
dc.identifier.citedreference | Motoyama N et al. ( 1995 ) Massive cell death of immature hematopoietic cells and neurons in Bcl‐x‐deficient mice. Science, 267, 1506 – 1510. | en_US |
dc.identifier.citedreference | Muchmore SW et al. ( 1996 ) X‐ray and NMR structure of human Bcl‐xL, an inhibitor of programmed cell death. Nature, 381, 335 – 341. | en_US |
dc.identifier.citedreference | Núñez G, London L, Hockenbery D, Alexander M, McKearn JP and Korsmeyer SJ ( 1990 ) Deregulated Bcl‐2 gene expression selectively prolongs survival of growth factor‐deprived hemopoietic cell lines. J Immunol, 144, 3602 – 3610. | en_US |
dc.identifier.citedreference | Oltvai ZN and Korsmeyer SJ ( 1994 ) Checkpoints of dueling dimers foil death wishes. Cell, 79, 189 – 192. | en_US |
dc.identifier.citedreference | Oltvai ZN, Milliman CL and Korsmeyer SJ ( 1993 ) Bcl‐2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell, 74, 609 – 619. | en_US |
dc.identifier.citedreference | Sato T et al. ( 1994 ) Interactions among members of the Bcl‐2 family analyzed with a yeast two‐hybrid system. Proc Natl Acad Sci USA, 91, 9283 – 9242. | en_US |
dc.identifier.citedreference | Shaw G and Kamen R ( 1986 ) A conserved AU sequence from the 3′ untranslated region of GM‐CSF mRNA mediates selective mRNA degradation. Cell, 46, 659 – 667. | en_US |
dc.identifier.citedreference | Simonian PL, Grillot DAM, Merino R and Núñez G ( 1996 ) Bax can antagonize Bcl‐X L during etoposide and cisplatin‐induced cell death independently of its heterodimerization with Bcl‐X L. J Biol Chem, 271, 22764 – 22772. | en_US |
dc.identifier.citedreference | Takayama S, Sato T, Krajewski S, Kochel K, Irie S, Millan JA and Reed JC ( 1995 ) Cloning and functional analysis of BAG‐1: a novel Bcl‐2‐binding protein with anti‐cell death activity. Cell, 80, 279 – 284. | en_US |
dc.identifier.citedreference | Thompson CB ( 1995 ) Apoptosis in the pathogenesis and treatment of disease. Science, 267, 1456 – 1462. | en_US |
dc.identifier.citedreference | Vaux DL, Cory S and Adams JM ( 1988 ) Bcl‐2 gene promotes haemopoietic cell survival and cooperates with c‐myc to immortalize pre‐B cells. Nature, 335, 440 – 442. | en_US |
dc.identifier.citedreference | Veis DJ, Sorenson CM, Shutter JR and Korsmeyer SJ ( 1993 ) Bcl‐2‐deficient mice demonstrate fulminant lymphoid apoptosis, polycystic disease, and hypopigmented hair. Cell, 75, 229 – 240. | en_US |
dc.identifier.citedreference | Wang HG, Takayama S, Rapp UR and Reed JC ( 1996 ) Bcl‐2 interacting protein, BAG‐1, binds to and activates the kinase Raf‐1. Proc Natl Acad Sci USA, 93, 7063 – 7068. | en_US |
dc.identifier.citedreference | White E ( 1996 ) Life, death and the pursuit of apoptosis. Genes Dev, 10, 1 – 15. | en_US |
dc.identifier.citedreference | White E, Cipriani R, Sabbatini P and Denton A ( 1991 ) Adenovirus E1B 19‐kilodalton protein overcomes the cytotoxicity of E1A proteins. J Virol, 65, 2968 – 2978. | en_US |
dc.identifier.citedreference | Yamagata K, Sanders LK, Kaufmann WE, Yee Y, Barnes CA, Nathans D and Worley PF ( 1994 ) RheB, a growth factor‐ and synaptic activity‐regulated gene, encodes a novel Ras‐related protein. J Biol Chem, 269, 16333 – 16339. | en_US |
dc.identifier.citedreference | Yang E, Zha J, Jockel J, Boise LH, Thompson CB and Korsmeyer SJ ( 1995 ) Bacl, a heterodimeric partner for Bcl‐xL and Bcl‐2, displaces Bax and promotes cell death. Cell, 80, 285 – 291. | en_US |
dc.identifier.citedreference | Zha H, Aimé‐Sempé C, Sato T and Reed JC ( 1996 ) Proapoptotic protein Bax heterodimerizes with Bcl‐2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2. J Biol Chem, 271, 7440 – 7444. | en_US |
dc.identifier.citedreference | Askew D, Ashmun R, Simmons B and Cleveland J ( 1991 ) Constitutive c‐ myc expression in an IL‐3‐dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis. Oncogene, 6, 1915 – 1922. | en_US |
dc.identifier.citedreference | Boise LH, González‐García M, Postema CE, Ding L, Lindsten T, Turka LA, Mao X, Núñez G and Thompson CB ( 1993 ) bcl‐x, a bcl‐2 related gene that functions as a dominant regulator of apoptotic cell death. Cell, 74, 597 – 608. | en_US |
dc.identifier.citedreference | Boise LH, Minn AJ, Noel PJ, June CH, Accavitti MA, Lindsten T and Thompson CB ( 1995 ) CD28 costimulation can promote T cell survival by enhancing the expression of Bcl‐X L. Immunity, 3, 87 – 98. | en_US |
dc.identifier.citedreference | Boyd JM, Malstrom S, Subramanian T, Venkatesh LK, Schaeper U, Elangovan B, D'Sa‐Eipper C and Chinnadural G ( 1994 ) Adenovirus E1B and 19 kDa and Bcl‐2 proteins interact with a common set of cellular proteins. Cell, 79, 341 – 351. | en_US |
dc.identifier.citedreference | Boyd JM et al. ( 1995 ) Bik, a novel death‐inducing protein shares a distinct sequence motif with Bcl‐2 family proteins and interacts with viral and cellular survival‐promoting proteins. Oncogene, 11, 1921 – 1928. | en_US |
dc.identifier.citedreference | Chinnaiyan AM, Orth K, O'Rourke K, Duan H, Poirier GG and Dixit VM ( 1996 ) Molecular ordering of the cell death pathway: Bcl‐2 and Bcl‐X L function upstream of the CED‐3‐like apoptotic proteases. J Biol Chem, 271, 4573 – 4576. | en_US |
dc.identifier.citedreference | Chittenden T, Harrington EA, O'Connor R, Flemington C, Lutz RJ, Evan GI and Guild BC ( 1995a ) Induction of apoptosis by the Bcl‐2 homologue Bak. Nature, 374, 733 – 736. | en_US |
dc.identifier.citedreference | Chittenden T, Flemington C, Houghton AB, Ebb GE, Gallo GJ, Elangovan B, Chinnadurai G and Lutz RJ ( 1995b ) A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions. EMBO J, 14, 5589 – 5596. | en_US |
dc.identifier.citedreference | Clarke MF et al. ( 1995 ) A recombinant bcl‐x s adenovirus selectively induces apoptosis in cancer cells, but not normal bone marrow cells. Proc Natl Acad Sci USA, 92, 11024 – 11028. | en_US |
dc.identifier.citedreference | Duke RC and Cohen JJ ( 1994 ) Morphological and biochemical assays of apoptosis. In Coligan,J.E., Kruisbeek,A.M., Margulies,D.H., Shevach,E.M. and Strober,W. (eds), Current Protocols in Immunology Current Protocols, NY, pp. 3.17.1 – 3.17.3. | en_US |
dc.identifier.citedreference | Evan GI, Wyllie AH, Gilbert CS, Littlewood TD, Land H, Brooks M, Waters CM, Penn LZ and Hancock DC ( 1992 ) Induction of apoptosis in fibroblasts by c‐myc protein. Cell, 69, 119 – 128. | en_US |
dc.identifier.citedreference | Farrow SN, White JH, Martinou I, Raven T, Pun KT, Grinham CJ, Martinou JC and Brown R ( 1995 ) Cloning of a bcl‐2 homologue by interaction with adenovirus E1B 19K. Nature, 374, 731 – 733. | en_US |
dc.identifier.citedreference | Feilotter HE, Hannon GJ, Ruddell CJ and Beach D ( 1994 ) Construction of an improved host strain for two hybrid screening. Nucleic Acids Res, 22, 1502 – 1503. | en_US |
dc.identifier.citedreference | Fernandez‐Sarabia MJ and Bischoff JR ( 1993 ) Bcl‐2 associates with the ras‐related protein R‐ras p23. Nature, 366, 274 – 275. | en_US |
dc.identifier.citedreference | González‐García M, Pérez‐Ballestero R, Ding L, Duan L, Boise LH, Thompson CB and Núñez G ( 1994 ) bcl‐x L is the major bcl‐x mRNA form expressed during murine development and its product localizes to mitochondria. Development, 120, 3033 – 3042. | en_US |
dc.identifier.citedreference | Han J, Sabbatini P, Perez D, Rao L, Modha D and White E ( 1996a ) The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53‐inducible and death‐promoting Bax protein. Genes Dev, 10, 461 – 477. | en_US |
dc.identifier.citedreference | Han J, Sabbatini P and White E ( 1996b ) Induction of apoptosis by human Nbk/Bik, a BH3‐containing protein that interacts with E1B 19K. Mol Cell Biol, 16, 5857 – 5864. | en_US |
dc.identifier.citedreference | Hannon GJ, Demetrick D and Beach D ( 1993 ) Isolation of the Rb‐related p130 through its interaction with CDK2 and cyclins. Genes Dev, 7, 2378 – 2391. | en_US |
dc.identifier.citedreference | Hockenbery D, Núñez G, Milliman C, Scheiber RD and Korsmeyer SJ ( 1991 ) Bcl‐2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature, 348, 334 – 336. | en_US |
dc.identifier.citedreference | Krajewski S, Tanaka S, Takeyama S, Schibler MJ, Fenton W and Reed JC ( 1993 ) Investigation of the subcellular distribution of the bcl‐2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes. Cancer Res, 53, 4701 – 4714. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.