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Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
dc.contributor.authorTanabe, Tsuyoshien_US
dc.contributor.authorChamaillard, Mathiasen_US
dc.contributor.authorOgura, Yasunorien_US
dc.contributor.authorZhu, Lien_US
dc.contributor.authorQiu, Suen_US
dc.contributor.authorMasumoto, Junyaen_US
dc.contributor.authorGhosh, Parthoen_US
dc.contributor.authorMoran, Anthonyen_US
dc.contributor.authorPredergast, Martina Men_US
dc.contributor.authorTromp, Gerarden_US
dc.contributor.authorWilliams, Charlene Jen_US
dc.contributor.authorInohara, Naohiroen_US
dc.contributor.authorNúñez, Gabrielen_US
dc.date.accessioned2014-01-08T20:34:42Z
dc.date.available2014-01-08T20:34:42Z
dc.date.issued2004-04-07en_US
dc.identifier.citationTanabe, Tsuyoshi; Chamaillard, Mathias; Ogura, Yasunori; Zhu, Li; Qiu, Su; Masumoto, Junya; Ghosh, Partho; Moran, Anthony; Predergast, Martina M; Tromp, Gerard; Williams, Charlene J; Inohara, Naohiro; Núñez, Gabriel (2004). "Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition." The EMBO Journal 23(7): 1587-1597. <http://hdl.handle.net/2027.42/102126>en_US
dc.identifier.issn0261-4189en_US
dc.identifier.issn1460-2075en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/102126
dc.publisherJohn Wiley & Sons, Ltden_US
dc.titleRegulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognitionen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.identifier.pmid15044951en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/102126/1/emboj7600175.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/102126/2/emboj7600175-sup-0004.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/102126/3/emboj7600175-sup-0001.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/102126/4/emboj7600175-sup-0002.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/102126/5/emboj7600175-sup-0003.pdf
dc.identifier.doi10.1038/sj.emboj.7600175en_US
dc.identifier.sourceThe EMBO Journalen_US
dc.identifier.citedreferenceMiceli‐Richard C, Lesage S, Rybojad M, Prieur AM, Manouvrier‐Hanu S, Hafner R, Chamaillard M, Zouali H, Thomas G, Hugot JP ( 2001 ) CARD15 mutations in Blau syndrome. Nat Genet 29: 19 – 20en_US
dc.identifier.citedreferenceHull KM, Shoham N, Chae JJ, Aksentijevich I, Kastner DL ( 2003 ) The expanding spectrum of systemic autoinflammatory disorders and their rheumatic manifestations. Curr Opin Rheumatol 15: 61 – 69en_US
dc.identifier.citedreferenceHwang CF, Bhakta AV, Truesdell GM, Pudlo WM, Williamson VM ( 2000 ) Evidence for a role of the N terminus and leucine‐rich repeat region of the Mi gene product in regulation of localized cell death. Plant Cell 12: 1319 – 1329en_US
dc.identifier.citedreferenceHwang CF, Williamson VM ( 2003 ) Leucine‐rich repeat‐mediated intramolecular interactions in nematode recognition and cell death signaling by the tomato resistance protein Mi. Plant J 34: 585 – 593en_US
dc.identifier.citedreferenceInohara N, Koseki T, del Peso L, Hu Y, Yee C, Chen S, Carrio R, Merino J, Liu D, Ni J, Nunez G ( 1999 ) Nod1, an Apaf‐1‐like activator of caspase‐9 and nuclear factor‐kappaB. J Biol Chem 274: 14560 – 14567en_US
dc.identifier.citedreferenceInohara N, Nunez G ( 2003 ) NODs: intracellular proteins involved in inflammation and apoptosis. Nat Rev Immunol 3: 371 – 382en_US
dc.identifier.citedreferenceInohara N, Ogura Y, Chen FF, Muto A, Nunez G ( 2001 ) Human Nod1 confers responsiveness to bacterial lipopolysaccharides. J Biol Chem 276: 2551 – 2554en_US
dc.identifier.citedreferenceInohara N, Ogura Y, Fontalba A, Gutierrez O, Pons F, Crespo J, Fukase K, Inamura S, Kusumoto S, Hashimoto M, Foster SJ, Moran AP, Fernandez‐Luna JL, Nunez G ( 2003 ) Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem 278: 5509 – 5512en_US
dc.identifier.citedreferenceKajava AV, Kobe B ( 2002 ) Assessment of the ability to model proteins with leucine‐rich repeats in light of the latest structural information. Protein Sci 11: 1082 – 1090en_US
dc.identifier.citedreferenceKobayashi K, Inohara N, Hernandez LD, Galan JE, Nunez G, Janeway CA, Medzhitov R, Flavell RA ( 2002 ) RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature 416: 194 – 199en_US
dc.identifier.citedreferenceKobe B, Deisenhofer J ( 1995 ) A structural basis of the interactions between leucine‐rich repeats and protein ligands. Nature 374: 183 – 186en_US
dc.identifier.citedreferenceLesage S, Zouali H, Cezard JP, Colombel JF, Belaiche J, Almer S, Tysk C, O'Morain C, Gassull M, Binder V, Finkel Y, Modigliani R, Gower‐Rousseau C, Macry J, Merlin F, Chamaillard M, Jannot AS, Thomas G, Hugot JP ( 2002 ) CARD15/NOD2 mutational analysis and genotype–phenotype correlation in 612 patients with inflammatory bowel disease. Am J Hum Genet 70: 845 – 857en_US
dc.identifier.citedreferenceMeyers BC, Kozik A, Griego A, Kuang H, Michelmore RW ( 2003 ) Genome‐wide analysis of NBS‐LRR‐encoding genes in Arabidopsis. Plant Cell 15: 809 – 834en_US
dc.identifier.citedreferenceMoffett P, Farnham G, Peart J, Baulcombe DC ( 2002 ) Interaction between domains of a plant NBS‐LRR protein in disease resistance‐related cell death. EMBO J 21: 4511 – 4519en_US
dc.identifier.citedreferenceOgura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R, Britton H, Moran T, Karaliuskas R, Duerr RH, Achkar JP, Brant SR, Bayless TM, Kirschner BS, Hanauer SB, Nunez G, Cho JH ( 2001a ) A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411: 603 – 606en_US
dc.identifier.citedreferenceOgura Y, Inohara N, Benito A, Chen FF, Yamaoka S, Nunez G ( 2001b ) Nod2, a Nod1/Apaf‐1 family member that is restricted to monocytes and activates NF‐kappaB. J Biol Chem 276: 4812 – 4818en_US
dc.identifier.citedreferenceOgura Y, Saab L, Chen FF, Benito A, Inohara N, Nunez G ( 2003 ) Genetic variation and activity of mouse Nod2, a susceptibility gene for Crohn's disease small star, filled. Genomics 81: 369 – 377en_US
dc.identifier.citedreferencePapageorgiou AC, Shapiro R, Acharya KR ( 1997 ) Molecular recognition of human angiogenin by placental ribonuclease inhibitor—an X‐ray crystallographic study at 2.0 Å resolution. EMBO J 16: 5162 – 5177en_US
dc.identifier.citedreferencePrice SR, Evans PR, Nagai K ( 1998 ) Crystal structure of the spliceosomal U2B′–U2A′ protein complex bound to a fragment of U2 small nuclear RNA. Nature 394: 645 – 650en_US
dc.identifier.citedreferenceRasmussen SA, Friedman JM ( 2000 ) NF1 gene and neurofibromatosis 1. Am J Epidemiol 151: 33 – 40en_US
dc.identifier.citedreferenceShafikhani S, Siegel RA, Ferrari E, Schellenberger V ( 1997 ) Generation of large libraries of random mutants in Bacillus subtilis by PCR‐based plasmid multimerization. Biotechniques 23: 304 – 310en_US
dc.identifier.citedreferenceShirano Y, Kachroo P, Shah J, Klessig DF ( 2002 ) A gain‐of‐function mutation in an Arabidopsis Toll Interleukin1 receptor‐nucleotide binding site‐leucine‐rich repeat type R gene triggers defense responses and results in enhanced disease resistance. Plant Cell 14: 3149 – 3162en_US
dc.identifier.citedreferencevan der Biezen EA, Jones JD ( 1998 ) The NB‐ARC domain: a novel signalling motif shared by plant resistance gene products and regulators of cell death in animals. Curr Biol 8: R226 – R227en_US
dc.identifier.citedreferenceWalker JE, Saraste M, Runswick MJ, Gay NJ ( 1982 ) Distantly related sequences in the alpha‐ and beta‐subunits of ATP synthase, myosin, kinases and other ATP‐requiring enzymes and a common nucleotide binding fold. EMBO J 1: 945 – 951en_US
dc.identifier.citedreferenceZhang Y, Goritschnig S, Dong X, Li X ( 2003 ) A gain‐of‐function mutation in a plant disease resistance gene leads to constitutive activation of downstream signal transduction pathways in suppressor of npr1‐1, constitutive 1. Plant Cell 15: 2636 – 2646en_US
dc.identifier.citedreferenceBendahmane A, Farnham G, Moffett P, Baulcombe DC ( 2002 ) Constitutive gain‐of‐function mutants in a nucleotide binding site‐leucine rich repeat protein encoded at the Rx locus of potato. Plant J 32: 195 – 204en_US
dc.identifier.citedreferenceBertin J, Nir WJ, Fischer CM, Tayber OV, Errada PR, Grant JR, Keilty JJ, Gosselin ML, Robison KE, Wong GH, Glucksmann MA, DiStefano PS ( 1999 ) Human CARD4 protein is a novel CED‐4/Apaf‐1 cell death family member that activates NF‐kappaB. J Biol Chem 274: 12955 – 12958en_US
dc.identifier.citedreferenceBonen DK, Ogura Y, Nicolae DL, Inohara N, Saab L, Tanabe T, Chen FF, Foster SJ, Duerr RH, Brant SR, Cho JH, Nunez G ( 2003 ) Crohn's disease‐associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan. Gastroenterology 124: 140 – 146en_US
dc.identifier.citedreferenceBrunger AT, Adams PD, Clore GM, DeLano WL, Gros P, Grosse‐Kunstleve RW, Jiang JS, Kuszewski J, Nilges M, Pannu NS, Read RJ, Rice LM, Simonson T, Warren GL ( 1998 ) Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr D 54 (Part 5): 905 – 921en_US
dc.identifier.citedreferenceChamaillard M, Girardin SE, Viala J, Philpott DJ ( 2003a ) Nods, Nalps and Naip: intracellular regulators of bacterial‐induced inflammation. Cell Microbiol 5: 581 – 592en_US
dc.identifier.citedreferenceChamaillard M, Hashimoto M, Horie Y, Masumoto J, Qiu S, Saab L, Ogura Y, Kawasaki A, Fukase K, Kusumoto S, Valvano MA, Foster SJ, Mak TW, Nunez G, Inohara N ( 2003b ) An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat Immunol 4: 702 – 707en_US
dc.identifier.citedreferenceChamaillard M, Philpott D, Girardin SE, Zouali H, Lesage S, Chareyre F, Bui TH, Giovannini M, Zaehringer U, Penard‐Lacronique V, Sansonetti PJ, Hugot JP, Thomas G ( 2003c ) Gene–environment interaction modulated by allelic heterogeneity in inflammatory diseases. Proc Natl Acad Sci USA 100: 3455 – 3460en_US
dc.identifier.citedreferenceDangl JL, Jones JD ( 2001 ) Plant pathogens and integrated defence responses to infection. Nature 411: 826 – 833en_US
dc.identifier.citedreferenceDodds PN, Lawrence GJ, Ellis JG ( 2001 ) Six amino acid changes confined to the leucine‐rich repeat beta‐strand/beta‐turn motif determine the difference between the P and P2 rust resistance specificities in flax. Plant Cell 13: 163 – 178en_US
dc.identifier.citedreferenceGirardin SE, Boneca IG, Viala J, Chamaillard M, Labigne A, Thomas G, Philpott DJ, Sansonetti PJ ( 2003a ) Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem 278: 8869 – 8872en_US
dc.identifier.citedreferenceGirardin SE, Sansonetti PJ, Philpott DJ ( 2002 ) Intracellular vs extracellular recognition of pathogens—common concepts in mammals and flies. Trends Microbiol 10: 193 – 199en_US
dc.identifier.citedreferenceGirardin SE, Travassos LH, Herve M, Blanot D, Boneca IG, Philpott DJ, Sansonetti PJ, Mengin‐Lecreulx D ( 2003b ) Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2. J Biol Chem 278: 41702 – 41708en_US
dc.identifier.citedreferenceHampe J, Cuthbert A, Croucher PJ, Mirza MM, Mascheretti S, Fisher S, Frenzel H, King K, Hasselmeyer A, MacPherson AJ, Bridger S, van Deventer S, Forbes A, Nikolaus S, Lennard‐Jones JE, Foelsch UR, Krawczak M, Lewis C, Schreiber S, Mathew CG ( 2001 ) Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet 357: 1925 – 1928en_US
dc.identifier.citedreferenceHugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J, Almer S, Tysk C, O'Morain CA, Gassull M, Binder V, Finkel Y, Cortot A, Modigliani R, Laurent‐Puig P, Gower‐Rousseau C, Macry J, Colombel JF, Sahbatou M, Thomas G ( 2001 ) Association of NOD2 leucine‐rich repeat variants with susceptibility to Crohn's disease. Nature 411: 599 – 603en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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