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Role of Nlrp6 and Nlrp12 in the maintenance of intestinal homeostasis

dc.contributor.authorChen, Grace Y.en_US
dc.date.accessioned2014-02-11T17:56:50Z
dc.date.available2015-04-01T19:59:06Zen_US
dc.date.issued2014-02en_US
dc.identifier.citationChen, Grace Y. (2014). "Role of Nlrp6 and Nlrp12 in the maintenance of intestinal homeostasis." European Journal of Immunology 44(2): 321-327.en_US
dc.identifier.issn0014-2980en_US
dc.identifier.issn1521-4141en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/102624
dc.publisherWiley Periodicals, Inc.en_US
dc.subject.otherImmune Regulationen_US
dc.subject.otherImmune Responsesen_US
dc.subject.otherCanceren_US
dc.subject.otherInnate Immunityen_US
dc.subject.otherInflammationen_US
dc.titleRole of Nlrp6 and Nlrp12 in the maintenance of intestinal homeostasisen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/102624/1/eji2871.pdf
dc.identifier.doi10.1002/eji.201344135en_US
dc.identifier.sourceEuropean Journal of Immunologyen_US
dc.identifier.citedreferenceSun, Y., Zhang, M., Chen, C. C., Gillilland, M., 3rd, Sun, X., El‐Zaatari, M., Huffnagle, G. B. et al., Stress‐induced corticotropin‐releasing hormone‐mediated NLRP6 inflammasome inhibition and transmissible enteritis in mice. Gastroenterology 2013. 144: 1478 – 1487.en_US
dc.identifier.citedreferenceLamkanfi, M., Kanneganti, T. D., Van Damme, P., Vanden Berghe, T., Vanoverberghe, I., Vandekerckhove, J., Vandenabeele, P. et al., Targeted peptidecentric proteomics reveals caspase‐7 as a substrate of the caspase‐1 inflammasomes. Mol. Cell. Proteomics 2008. 7: 2350 – 2363.en_US
dc.identifier.citedreferenceFernandes‐Alnemri, T. and Alnemri, E. S., Assembly, purification, and assay of the activity of the ASC pyroptosome. Methods Enzymol. 2008. 442: 251 – 270.en_US
dc.identifier.citedreferenceVladimer, G. I., Weng, D., Paquette, S. W., Vanaja, S. K., Rathinam, V. A., Aune, M. H., Conlon, J. E. et al., The NLRP12 inflammasome recognizes Yersinia pestis. Immunity 2012. 37: 96 – 107.en_US
dc.identifier.citedreferenceAnand, P. K., Malireddi, R. K., Lukens, J. R., Vogel, P., Bertin, J., Lamkanfi, M. and Kanneganti, T. D., NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens. Nature 2012. 488: 389 – 393.en_US
dc.identifier.citedreferenceWilliams, K. L., Lich, J. D., Duncan, J. A., Reed, W., Rallabhandi, P., Moore, C., Kurtz, S. et al. The CATERPILLER protein monarch‐1 is an antagonist of toll‐like receptor‐, tumor necrosis factor alpha‐, and Mycobacterium tuberculosis‐induced pro‐inflammatory signals. J. Biol. Chem. 2005. 280: 39914 – 39924.en_US
dc.identifier.citedreferenceLich, J. D., Williams, K. L., Moore, C. B., Arthur, J. C., Davis, B. K., Taxman, D. J. and Ting, J. P., Monarch‐1 suppresses non‐canonical NF‐kappaB activation and p52‐dependent chemokine expression in monocytes. J. Immunol. 2007. 178: 1256 – 1260.en_US
dc.identifier.citedreferenceAllen, I. C., McElvania‐TeKippe, E., Wilson, J. E., Lich, J. D., Arthur, J. C., Sullivan, J. T., Braunstein, M. et al., Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis. PLoS One 2013. 8: e60842.en_US
dc.identifier.citedreferenceGarrett, W. S., Gallini, C. A., Yatsunenko, T., Michaud, M., DuBois, A., Delaney, M. L., Punit, S. et al., Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Cell Host Microbe 2010. 8: 292 – 300.en_US
dc.identifier.citedreferenceHu, B., Elinav, E., Huber, S., Strowig, T., Hao, L., Hafemann, A., Jin, C. et al., Microbiota‐induced activation of epithelial IL‐6 signaling links inflammasome‐driven inflammation with transmissible cancer. Proc. Natl. Acad. Sci. USA 2013. 110: 9862 – 9867.en_US
dc.identifier.citedreferenceHirota, S. A., Ng, J., Lueng, A., Khajah, M., Parhar, K., Li, Y., Lam, V. et al., NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis. Inflamm. Bowel. Dis. 2011. 17: 1359 – 1372.en_US
dc.identifier.citedreferenceUbeda, C., Lipuma, L., Gobourne, A., Viale, A., Leiner, I., Equinda, M., Khanin, R. et al., Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR‐deficient mice. J. Exp. Med. 2012. 209: 1445 – 1456.en_US
dc.identifier.citedreferenceSalcedo, R., Worschech, A., Cardone, M., Jones, Y., Gyulai, Z., Dai, R. M., Wang, E. et al., MyD88‐mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18. J. Exp. Med. 2010. 207: 1625 – 1636.en_US
dc.identifier.citedreferenceHuber, S., Gagliani, N., Zenewicz, L. A., Huber, F. J., Bosurgi, L., Hu, B., Hedl, M. et al., IL‐22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature 2012. 491: 259 – 263.en_US
dc.identifier.citedreferencePickert, G., Neufert, C., Leppkes, M., Zheng, Y., Wittkopf, N., Warntjen, M., Lehr, H. A. et al., STAT3 links IL‐22 signaling in intestinal epithelial cells to mucosal wound healing. J. Exp. Med. 2009. 206: 1465 – 1472.en_US
dc.identifier.citedreferenceWitte, E., Witte, K., Warszawska, K., Sabat, R. and Wolk, K., Interleukin‐22: a cytokine produced by T, NK and NKT cell subsets, with importance in the innate immune defense and tissue protection. Cytokine. Growth Factor Rev. 2010. 21: 365 – 379.en_US
dc.identifier.citedreferenceKempster, S. L., Belteki, G., Forhead, A. J., Fowden, A. L., Catalano, R. D., Lam, B. Y., McFarlane, I. et al., Developmental control of the Nlrp6 inflammasome and a substrate, IL‐18, in mammalian intestine. Am. J. Physiol. Gastrointest. Liver Physiol. 2011. 300: G253 – 263.en_US
dc.identifier.citedreferenceDhawan, P. and Richmond, A., A novel NF‐kappa B‐inducing kinase‐MAPK signaling pathway up‐regulates NF‐kappa B activity in melanoma cells. J. Biol. Chem. 2002. 277: 7920 – 7928.en_US
dc.identifier.citedreferenceAdli, M., Merkhofer, E., Cogswell, P. and Baldwin, A. S., IKKalpha and IKKbeta each function to regulate NF‐kappaB activation in the TNF‐induced/canonical pathway. PLoS One 2010. 5: e9428.en_US
dc.identifier.citedreferenceZarnegar, B., Yamazaki, S., He, J. Q. and Cheng, G., Control of canonical NF‐kappaB activation through the NIK‐IKK complex pathway. Proc. Natl. Acad. Sci. USA 2008. 105: 3503 – 3508.en_US
dc.identifier.citedreferenceRakoff‐Nahoum, S., Paglino, J., Eslami‐Varzaneh, F., Edberg, S. and Medzhitov, R., Recognition of commensal microflora by toll‐like receptors is required for intestinal homeostasis. Cell 2004. 118: 229 – 241.en_US
dc.identifier.citedreferenceChen, G. Y., Shaw, M. H., Redondo, G. and Nunez, G., The innate immune receptor Nod1 protects the intestine from inflammation‐induced tumorigenesis. Cancer Res. 2008. 68: 10060 – 10067.en_US
dc.identifier.citedreferenceCouturier‐Maillard, A., Secher, T., Rehman, A., Normand, S., De Arcangelis, A., Haesler, R., Huot, L. et al., NOD2‐mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer. J. Clin. Invest. 2013 123: 700 – 711.en_US
dc.identifier.citedreferenceZaki, M. H., Boyd, K. L., Vogel, P., Kastan, M. B., Lamkanfi, M. and Kanneganti, T. D., The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity 2010. 32: 379 – 391.en_US
dc.identifier.citedreferenceZaki, M. H., Vogel, P., Body‐Malapel, M., Lamkanfi, M. and Kanneganti, T. D., IL‐18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation. J. Immunol. 2010. 185: 4912 – 4920.en_US
dc.identifier.citedreferenceAllen, I. C., TeKippe, E. M., Woodford, R. M., Uronis, J. M., Holl, E. K., Rogers, A. B., Herfarth, H. H. et al., The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis‐associated cancer. J. Exp. Med. 2010. 207: 1045 – 1056.en_US
dc.identifier.citedreferenceElinav, E., Strowig, T., Kau, A. L., Henao‐Mejia, J., Thaiss, C. A., Booth, C. J., Peaper, D. R. et al., NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 2011. 145: 745 – 757.en_US
dc.identifier.citedreferenceChen, G. Y., Liu, M., Wang, F., Bertin, J. and Nunez, G., A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. J. Immunol. 2011. 186: 7187 – 7194.en_US
dc.identifier.citedreferenceNormand, S., Delanoye‐Crespin, A., Bressenot, A., Huot, L., Grandjean, T., Peyrin‐Biroulet, L., Lemoine, Y. et al., Nod‐like receptor pyrin domain‐containing protein 6 (NLRP6) controls epithelial self‐renewal and colorectal carcinogenesis upon injury. Proc. Natl. Acad Sci. USA 2011. 108: 9601 – 9606.en_US
dc.identifier.citedreferenceFranchi, L., Amer, A., Body‐Malapel, M., Kanneganti, T. D., Ozoren, N., Jagirdar, R., Inohara, N. et al., Cytosolic flagellin requires Ipaf for activation of caspase‐1 and interleukin 1beta in salmonella‐infected macrophages. Nat. Immunol. 2006. 7: 576 – 582.en_US
dc.identifier.citedreferenceInohara, N., Ogura, Y., Fontalba, A., Gutierrez, O., Pons, F., Crespo, J., Fukase, K. et al., Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J. Biol. Chem. 2003. 278: 5509 – 5512.en_US
dc.identifier.citedreferenceChen, G. Y. and Nunez, G., Sterile inflammation: sensing and reacting to damage. Nat. Rev. Immunol. 2010. 10: 826 – 837.en_US
dc.identifier.citedreferenceInohara, N., Koseki, T., Lin, J., del Peso, L., Lucas, P. C., Chen, F. F., Ogura, Y. et al., An induced proximity model for NF‐kappa B activation in the Nod1/RICK and RIP signaling pathways. J. Biol. Chem. 2000. 275: 27823 – 27831.en_US
dc.identifier.citedreferenceTing, J. P., Lovering, R. C., Alnemri, E. S., Bertin, J., Boss, J. M., Davis, B. K., Flavell, R. A. et al., The NLR gene family: a standard nomenclature. Immunity 2008. 28: 285 – 287.en_US
dc.identifier.citedreferenceAllen, I. C., Wilson, J. E., Schneider, M., Lich, J. D., Roberts, R. A., Arthur, J. C., Woodford, R. M. et al., NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF‐kappaB signaling. Immunity 2012. 36: 742 – 754.en_US
dc.identifier.citedreferenceZaki, M. H., Vogel, P., Malireddi, R. K., Body‐Malapel, M., Anand, P. K., Bertin, J., Green, D. R., et al., The NOD‐like receptor NLRP12 attenuates colon inflammation and tumorigenesis. Cancer Cell 2011. 20: 649 – 660.en_US
dc.identifier.citedreferenceCouturier‐Maillard, A., Secher, T., Rehman, A., Normand, S., De Arcangelis, A., Haesler, R., Huot, L. et al., NOD2‐mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer. J. Clin. Invest. 2013. 123: 700 – 711.en_US
dc.identifier.citedreferenceHu, B., Elinav, E., Huber, S., Booth, C. J., Strowig, T., Jin, C., Eisenbarth, S. C. et al., Inflammation‐induced tumorigenesis in the colon is regulated by caspase‐1 and NLRC4. Proc. Natl. Acad Sci. USA 2010. 107: 21635 – 21640.en_US
dc.identifier.citedreferenceWang, L., Manji, G. A., Grenier, J. M., Al‐Garawi, A., Merriam, S., Lora, J. M., Geddes, B. J. et al., PYPAF7, a novel PYRIN‐containing Apaf1‐like protein that regulates activation of NF‐kappa B and caspase‐1‐dependent cytokine processing. J. Biol. Chem. 2002. 277: 29874 – 29880.en_US
dc.identifier.citedreferenceGrenier, J. M., Wang, L., Manji, G. A., Huang, W. J., Al‐Garawi, A., Kelly, R., Carlson, A. et al., Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF‐kappaB and caspase‐1. FEBS. Lett. 2002. 530: 73 – 78.en_US
dc.identifier.citedreferenceSrinivasula, S. M., Poyet, J. L., Razmara, M., Datta, P., Zhang, Z. and Alnemri, E. S., The PYRIN‐CARD protein ASC is an activating adaptor for caspase‐1. J. Biol. Chem. 2002. 277: 21119 – 21122.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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