Role of Nlrp6 and Nlrp12 in the maintenance of intestinal homeostasis
dc.contributor.author | Chen, Grace Y. | en_US |
dc.date.accessioned | 2014-02-11T17:56:50Z | |
dc.date.available | 2015-04-01T19:59:06Z | en_US |
dc.date.issued | 2014-02 | en_US |
dc.identifier.citation | Chen, Grace Y. (2014). "Role of Nlrp6 and Nlrp12 in the maintenance of intestinal homeostasis." European Journal of Immunology 44(2): 321-327. | en_US |
dc.identifier.issn | 0014-2980 | en_US |
dc.identifier.issn | 1521-4141 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/102624 | |
dc.publisher | Wiley Periodicals, Inc. | en_US |
dc.subject.other | Immune Regulation | en_US |
dc.subject.other | Immune Responses | en_US |
dc.subject.other | Cancer | en_US |
dc.subject.other | Innate Immunity | en_US |
dc.subject.other | Inflammation | en_US |
dc.title | Role of Nlrp6 and Nlrp12 in the maintenance of intestinal homeostasis | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/102624/1/eji2871.pdf | |
dc.identifier.doi | 10.1002/eji.201344135 | en_US |
dc.identifier.source | European Journal of Immunology | en_US |
dc.identifier.citedreference | Sun, Y., Zhang, M., Chen, C. C., Gillilland, M., 3rd, Sun, X., El‐Zaatari, M., Huffnagle, G. B. et al., Stress‐induced corticotropin‐releasing hormone‐mediated NLRP6 inflammasome inhibition and transmissible enteritis in mice. Gastroenterology 2013. 144: 1478 – 1487. | en_US |
dc.identifier.citedreference | Lamkanfi, M., Kanneganti, T. D., Van Damme, P., Vanden Berghe, T., Vanoverberghe, I., Vandekerckhove, J., Vandenabeele, P. et al., Targeted peptidecentric proteomics reveals caspase‐7 as a substrate of the caspase‐1 inflammasomes. Mol. Cell. Proteomics 2008. 7: 2350 – 2363. | en_US |
dc.identifier.citedreference | Fernandes‐Alnemri, T. and Alnemri, E. S., Assembly, purification, and assay of the activity of the ASC pyroptosome. Methods Enzymol. 2008. 442: 251 – 270. | en_US |
dc.identifier.citedreference | Vladimer, G. I., Weng, D., Paquette, S. W., Vanaja, S. K., Rathinam, V. A., Aune, M. H., Conlon, J. E. et al., The NLRP12 inflammasome recognizes Yersinia pestis. Immunity 2012. 37: 96 – 107. | en_US |
dc.identifier.citedreference | Anand, P. K., Malireddi, R. K., Lukens, J. R., Vogel, P., Bertin, J., Lamkanfi, M. and Kanneganti, T. D., NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens. Nature 2012. 488: 389 – 393. | en_US |
dc.identifier.citedreference | Williams, K. L., Lich, J. D., Duncan, J. A., Reed, W., Rallabhandi, P., Moore, C., Kurtz, S. et al. The CATERPILLER protein monarch‐1 is an antagonist of toll‐like receptor‐, tumor necrosis factor alpha‐, and Mycobacterium tuberculosis‐induced pro‐inflammatory signals. J. Biol. Chem. 2005. 280: 39914 – 39924. | en_US |
dc.identifier.citedreference | Lich, J. D., Williams, K. L., Moore, C. B., Arthur, J. C., Davis, B. K., Taxman, D. J. and Ting, J. P., Monarch‐1 suppresses non‐canonical NF‐kappaB activation and p52‐dependent chemokine expression in monocytes. J. Immunol. 2007. 178: 1256 – 1260. | en_US |
dc.identifier.citedreference | Allen, I. C., McElvania‐TeKippe, E., Wilson, J. E., Lich, J. D., Arthur, J. C., Sullivan, J. T., Braunstein, M. et al., Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis. PLoS One 2013. 8: e60842. | en_US |
dc.identifier.citedreference | Garrett, W. S., Gallini, C. A., Yatsunenko, T., Michaud, M., DuBois, A., Delaney, M. L., Punit, S. et al., Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Cell Host Microbe 2010. 8: 292 – 300. | en_US |
dc.identifier.citedreference | Hu, B., Elinav, E., Huber, S., Strowig, T., Hao, L., Hafemann, A., Jin, C. et al., Microbiota‐induced activation of epithelial IL‐6 signaling links inflammasome‐driven inflammation with transmissible cancer. Proc. Natl. Acad. Sci. USA 2013. 110: 9862 – 9867. | en_US |
dc.identifier.citedreference | Hirota, S. A., Ng, J., Lueng, A., Khajah, M., Parhar, K., Li, Y., Lam, V. et al., NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis. Inflamm. Bowel. Dis. 2011. 17: 1359 – 1372. | en_US |
dc.identifier.citedreference | Ubeda, C., Lipuma, L., Gobourne, A., Viale, A., Leiner, I., Equinda, M., Khanin, R. et al., Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR‐deficient mice. J. Exp. Med. 2012. 209: 1445 – 1456. | en_US |
dc.identifier.citedreference | Salcedo, R., Worschech, A., Cardone, M., Jones, Y., Gyulai, Z., Dai, R. M., Wang, E. et al., MyD88‐mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18. J. Exp. Med. 2010. 207: 1625 – 1636. | en_US |
dc.identifier.citedreference | Huber, S., Gagliani, N., Zenewicz, L. A., Huber, F. J., Bosurgi, L., Hu, B., Hedl, M. et al., IL‐22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature 2012. 491: 259 – 263. | en_US |
dc.identifier.citedreference | Pickert, G., Neufert, C., Leppkes, M., Zheng, Y., Wittkopf, N., Warntjen, M., Lehr, H. A. et al., STAT3 links IL‐22 signaling in intestinal epithelial cells to mucosal wound healing. J. Exp. Med. 2009. 206: 1465 – 1472. | en_US |
dc.identifier.citedreference | Witte, E., Witte, K., Warszawska, K., Sabat, R. and Wolk, K., Interleukin‐22: a cytokine produced by T, NK and NKT cell subsets, with importance in the innate immune defense and tissue protection. Cytokine. Growth Factor Rev. 2010. 21: 365 – 379. | en_US |
dc.identifier.citedreference | Kempster, S. L., Belteki, G., Forhead, A. J., Fowden, A. L., Catalano, R. D., Lam, B. Y., McFarlane, I. et al., Developmental control of the Nlrp6 inflammasome and a substrate, IL‐18, in mammalian intestine. Am. J. Physiol. Gastrointest. Liver Physiol. 2011. 300: G253 – 263. | en_US |
dc.identifier.citedreference | Dhawan, P. and Richmond, A., A novel NF‐kappa B‐inducing kinase‐MAPK signaling pathway up‐regulates NF‐kappa B activity in melanoma cells. J. Biol. Chem. 2002. 277: 7920 – 7928. | en_US |
dc.identifier.citedreference | Adli, M., Merkhofer, E., Cogswell, P. and Baldwin, A. S., IKKalpha and IKKbeta each function to regulate NF‐kappaB activation in the TNF‐induced/canonical pathway. PLoS One 2010. 5: e9428. | en_US |
dc.identifier.citedreference | Zarnegar, B., Yamazaki, S., He, J. Q. and Cheng, G., Control of canonical NF‐kappaB activation through the NIK‐IKK complex pathway. Proc. Natl. Acad. Sci. USA 2008. 105: 3503 – 3508. | en_US |
dc.identifier.citedreference | Rakoff‐Nahoum, S., Paglino, J., Eslami‐Varzaneh, F., Edberg, S. and Medzhitov, R., Recognition of commensal microflora by toll‐like receptors is required for intestinal homeostasis. Cell 2004. 118: 229 – 241. | en_US |
dc.identifier.citedreference | Chen, G. Y., Shaw, M. H., Redondo, G. and Nunez, G., The innate immune receptor Nod1 protects the intestine from inflammation‐induced tumorigenesis. Cancer Res. 2008. 68: 10060 – 10067. | en_US |
dc.identifier.citedreference | Couturier‐Maillard, A., Secher, T., Rehman, A., Normand, S., De Arcangelis, A., Haesler, R., Huot, L. et al., NOD2‐mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer. J. Clin. Invest. 2013 123: 700 – 711. | en_US |
dc.identifier.citedreference | Zaki, M. H., Boyd, K. L., Vogel, P., Kastan, M. B., Lamkanfi, M. and Kanneganti, T. D., The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity 2010. 32: 379 – 391. | en_US |
dc.identifier.citedreference | Zaki, M. H., Vogel, P., Body‐Malapel, M., Lamkanfi, M. and Kanneganti, T. D., IL‐18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation. J. Immunol. 2010. 185: 4912 – 4920. | en_US |
dc.identifier.citedreference | Allen, I. C., TeKippe, E. M., Woodford, R. M., Uronis, J. M., Holl, E. K., Rogers, A. B., Herfarth, H. H. et al., The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis‐associated cancer. J. Exp. Med. 2010. 207: 1045 – 1056. | en_US |
dc.identifier.citedreference | Elinav, E., Strowig, T., Kau, A. L., Henao‐Mejia, J., Thaiss, C. A., Booth, C. J., Peaper, D. R. et al., NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 2011. 145: 745 – 757. | en_US |
dc.identifier.citedreference | Chen, G. Y., Liu, M., Wang, F., Bertin, J. and Nunez, G., A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. J. Immunol. 2011. 186: 7187 – 7194. | en_US |
dc.identifier.citedreference | Normand, S., Delanoye‐Crespin, A., Bressenot, A., Huot, L., Grandjean, T., Peyrin‐Biroulet, L., Lemoine, Y. et al., Nod‐like receptor pyrin domain‐containing protein 6 (NLRP6) controls epithelial self‐renewal and colorectal carcinogenesis upon injury. Proc. Natl. Acad Sci. USA 2011. 108: 9601 – 9606. | en_US |
dc.identifier.citedreference | Franchi, L., Amer, A., Body‐Malapel, M., Kanneganti, T. D., Ozoren, N., Jagirdar, R., Inohara, N. et al., Cytosolic flagellin requires Ipaf for activation of caspase‐1 and interleukin 1beta in salmonella‐infected macrophages. Nat. Immunol. 2006. 7: 576 – 582. | en_US |
dc.identifier.citedreference | Inohara, N., Ogura, Y., Fontalba, A., Gutierrez, O., Pons, F., Crespo, J., Fukase, K. et al., Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J. Biol. Chem. 2003. 278: 5509 – 5512. | en_US |
dc.identifier.citedreference | Chen, G. Y. and Nunez, G., Sterile inflammation: sensing and reacting to damage. Nat. Rev. Immunol. 2010. 10: 826 – 837. | en_US |
dc.identifier.citedreference | Inohara, N., Koseki, T., Lin, J., del Peso, L., Lucas, P. C., Chen, F. F., Ogura, Y. et al., An induced proximity model for NF‐kappa B activation in the Nod1/RICK and RIP signaling pathways. J. Biol. Chem. 2000. 275: 27823 – 27831. | en_US |
dc.identifier.citedreference | Ting, J. P., Lovering, R. C., Alnemri, E. S., Bertin, J., Boss, J. M., Davis, B. K., Flavell, R. A. et al., The NLR gene family: a standard nomenclature. Immunity 2008. 28: 285 – 287. | en_US |
dc.identifier.citedreference | Allen, I. C., Wilson, J. E., Schneider, M., Lich, J. D., Roberts, R. A., Arthur, J. C., Woodford, R. M. et al., NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF‐kappaB signaling. Immunity 2012. 36: 742 – 754. | en_US |
dc.identifier.citedreference | Zaki, M. H., Vogel, P., Malireddi, R. K., Body‐Malapel, M., Anand, P. K., Bertin, J., Green, D. R., et al., The NOD‐like receptor NLRP12 attenuates colon inflammation and tumorigenesis. Cancer Cell 2011. 20: 649 – 660. | en_US |
dc.identifier.citedreference | Couturier‐Maillard, A., Secher, T., Rehman, A., Normand, S., De Arcangelis, A., Haesler, R., Huot, L. et al., NOD2‐mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer. J. Clin. Invest. 2013. 123: 700 – 711. | en_US |
dc.identifier.citedreference | Hu, B., Elinav, E., Huber, S., Booth, C. J., Strowig, T., Jin, C., Eisenbarth, S. C. et al., Inflammation‐induced tumorigenesis in the colon is regulated by caspase‐1 and NLRC4. Proc. Natl. Acad Sci. USA 2010. 107: 21635 – 21640. | en_US |
dc.identifier.citedreference | Wang, L., Manji, G. A., Grenier, J. M., Al‐Garawi, A., Merriam, S., Lora, J. M., Geddes, B. J. et al., PYPAF7, a novel PYRIN‐containing Apaf1‐like protein that regulates activation of NF‐kappa B and caspase‐1‐dependent cytokine processing. J. Biol. Chem. 2002. 277: 29874 – 29880. | en_US |
dc.identifier.citedreference | Grenier, J. M., Wang, L., Manji, G. A., Huang, W. J., Al‐Garawi, A., Kelly, R., Carlson, A. et al., Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF‐kappaB and caspase‐1. FEBS. Lett. 2002. 530: 73 – 78. | en_US |
dc.identifier.citedreference | Srinivasula, S. M., Poyet, J. L., Razmara, M., Datta, P., Zhang, Z. and Alnemri, E. S., The PYRIN‐CARD protein ASC is an activating adaptor for caspase‐1. J. Biol. Chem. 2002. 277: 21119 – 21122. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.