let‐7‐repressesed S hc translation delays replicative senescence
dc.contributor.author | Xu, Fang | en_US |
dc.contributor.author | Pang, Lijun | en_US |
dc.contributor.author | Cai, Xiaoyu | en_US |
dc.contributor.author | Liu, Xinwen | en_US |
dc.contributor.author | Yuan, Shuai | en_US |
dc.contributor.author | Fan, Xiuqin | en_US |
dc.contributor.author | Jiang, Bin | en_US |
dc.contributor.author | Zhang, Xiaowei | en_US |
dc.contributor.author | Dou, Yali | en_US |
dc.contributor.author | Gorospe, Myriam | en_US |
dc.contributor.author | Wang, Wengong | en_US |
dc.date.accessioned | 2014-02-11T17:57:19Z | |
dc.date.available | 2015-04-01T19:59:07Z | en_US |
dc.date.issued | 2014-02 | en_US |
dc.identifier.citation | Xu, Fang; Pang, Lijun; Cai, Xiaoyu; Liu, Xinwen; Yuan, Shuai; Fan, Xiuqin; Jiang, Bin; Zhang, Xiaowei; Dou, Yali; Gorospe, Myriam; Wang, Wengong (2014). "let‐7‐repressesed S hc translation delays replicative senescence." Aging Cell 13(1): 185-192. | en_US |
dc.identifier.issn | 1474-9718 | en_US |
dc.identifier.issn | 1474-9726 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/102709 | |
dc.publisher | Wiley Periodicals, Inc. | en_US |
dc.subject.other | Cellular Lifespan | en_US |
dc.subject.other | Let‐7a | en_US |
dc.subject.other | P66 S Hc | en_US |
dc.subject.other | Replicative Senescence | en_US |
dc.subject.other | Translational Regulation | en_US |
dc.title | let‐7‐repressesed S hc translation delays replicative senescence | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/102709/1/acel12176.pdf | |
dc.identifier.doi | 10.1111/acel.12176 | en_US |
dc.identifier.source | Aging Cell | en_US |
dc.identifier.citedreference | Pratt AJ, MacRae IJ ( 2009 ) The RNA‐induced silencing complex: a versatile gene‐silencing machine. J. Biol. Chem. 284, 17897 – 17901. | en_US |
dc.identifier.citedreference | Czech B, Hannon GJ ( 2011 ) Small RNA sorting: matchmaking for Argonautes. Nat. Rev. Genet. 12, 19 – 31. | en_US |
dc.identifier.citedreference | Fabrizio P, Liou LL, Moy VN, Diaspro A, Valentine JS, Gralla EB, Longo VD ( 2003 ) SOD2 functions downstream of Sch9 to extend longevity in yeast. Genetics 163, 35 – 46. | en_US |
dc.identifier.citedreference | Favetta LA, Robert C, King WA, Betts DH ( 2004 ) Expression profiles of p53 and p66Shc during oxidative stress‐induced senescence in fetal bovine fibroblasts. Exp. Cell Res. 299, 36 – 48. | en_US |
dc.identifier.citedreference | He X, Duan C, Chen J, Ou‐Yang X, Zhang Z, Li C, Peng H ( 2009 ) Let‐7a elevates p21(WAF1) levels by targeting of NIRF and suppresses the growth of A549 lung cancer cells. FEBS Lett. 583, 3501 – 3507. | en_US |
dc.identifier.citedreference | Jing Q, Huang S, Guth S, Zarubin T, Motoyama A, Chen J, Di Padova F, Lin SC, Gram H, Han J ( 2005 ) Involvement of microRNA in AU‐rich element‐mediated mRNA instability. Cell 120, 623 – 634. | en_US |
dc.identifier.citedreference | Johnson CD, Esquela‐Kerscher A, Stefani G, Byrom M, Kelnar K, Ovcharenko D, Wilson M, Wang X, Shelton J, Shingara J, Chin L, Brown D, Slack FJ ( 2007 ) The let‐7 microRNA represses cell proliferation pathways in human cells. Cancer Res. 67, 7713 – 7722. | en_US |
dc.identifier.citedreference | Kumar MS, Erkeland SJ, Pester RE, Chen CY, Ebert MS, Sharp PA, Jacks T ( 2008 ) Suppression of non‐small cell lung tumor development by the let‐7 microRNA family. Proc. Natl Acad. Sci. USA 105, 3903 – 3908. | en_US |
dc.identifier.citedreference | Lebiedzinska M, Duszynski J, Rizzuto R, Pinton P, Wieckowski MR ( 2009 ) Age‐related changes in levels of p66Shc and serine 36‐phosphorylated p66Shc in organs and mouse tissues. Arch. Biochem. Biophys. 486, 73 – 80. | en_US |
dc.identifier.citedreference | Lee ST, Chu K, Oh HJ, Im WS, Lim JY, Kim SK, Park CK, Jung KH, Lee SK, Kim M, Roh JK ( 2011 ) Let‐7 microRNA inhibits the proliferation of human glioblastoma cells. J. Neurooncol. 102, 19 – 24. | en_US |
dc.identifier.citedreference | Legesse‐Miller A, Elemento O, Pfau SJ, Forman JJ, Tavazoie S, Coller HA ( 2009 ) let‐7 overexpression leads to an increased fraction of cells in G2/M, direct down‐regulation of Cdc34, and stabilization of Wee1 kinase in primary fibroblasts. J. Biol. Chem. 284, 6605 – 6609. | en_US |
dc.identifier.citedreference | Luzi L, Confalonieri S, Di Fiore PP, Pelicci PG ( 2000 ) Evolution of Shc functions from nematode to human. Curr. Opin. Genet. Dev. 10, 668 – 674. | en_US |
dc.identifier.citedreference | Marasa BS, Srikantan S, Martindale JL, Kim MM, Lee EK, Gorospe M, Abdelmohsen K ( 2010 ) MicroRNA profiling in human diploid fibroblasts uncovers miR‐519 role in replicative senescence. Aging (Albany NY) 2, 333 – 343. | en_US |
dc.identifier.citedreference | Migliaccio E, Mele S, Salcini AE, Pelicci G, Lai KM, Superti‐Furga G, Pawson T, Di Fiore PP, Lanfrancone L, Pelicci PG ( 1997 ) Opposite effects of the p52shc/p46shc and p66Shc splicing isoforms on the EGF receptor‐MAP kinase‐fos signalling pathway. EMBO J. 16, 706 – 716. | en_US |
dc.identifier.citedreference | Migliaccio E, Giorgio M, Mele S, Pelicci G, Reboldi P, Pandolfi PP, Lanfrancone L, Pelicci PG ( 1999 ) The p66Shc adaptor protein controls oxidative stress response and life span in mammals. Nature 402, 309 – 313. | en_US |
dc.identifier.citedreference | Napoli C, Martin‐Padura I, de Nigris F, Giorgio M, Mansueto G, Somma P, Condorelli M, Sica G, De Rosa G, Pelicci P ( 2003 ) Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high‐fat diet. Proc. Natl Acad. Sci. USA 100, 2112 – 2116. | en_US |
dc.identifier.citedreference | Parker JD, Parker KM, Sohal BH, Sohal RS, Keller L ( 2004 ) Decreased expression of Cu‐Zn superoxide dismutase 1 in ants with extreme lifespan. Proc. Natl Acad. Sci. USA 101, 3486 – 3489. | en_US |
dc.identifier.citedreference | Pinton P, Rizzuto R ( 2008 ) p66Shc, oxidative stress and aging: importing a lifespan determinant into mitochondria. Cell Cycle 7, 304 – 308. | en_US |
dc.identifier.citedreference | Rodier F, Campisi J ( 2011 ) Four faces of cellular senescence. J Cell Biol. 192, 547 – 556. | en_US |
dc.identifier.citedreference | Sampson VB, Rong NH, Han J, Yang Q, Aris V, Soteropoulos P, Petrelli NJ, Dunn SP, Krueger LJ ( 2007 ) MicroRNA let‐7a down‐regulates MYC and reverts MYC‐induced growth in Burkitt lymphoma cells. Cancer Res. 67, 9762 – 9770. | en_US |
dc.identifier.citedreference | Trinei M, Giorgio M, Cicalese A, Barozzi S, Ventura A, Migliaccio E, Milia E, Padura IM, Raker VA, Maccarana M, Petronilli V, Minucci S, Bernardi P, Lanfrancone L, Pelicci PG ( 2002 ) A p53‐p66Shc signalling pathway controls intracellular redox status, levels of oxidation‐damaged DNA and oxidative stress‐induced apoptosis. Oncogene 21, 3872 – 3878. | en_US |
dc.identifier.citedreference | Veeramani S, Igawa T, Yuan TC, Lin FF, Lee MS, Lin JS, Johansson SL, Lin MF ( 2005 ) Expression of p66(Shc) protein correlates with proliferation of human prostate cancer cells. Oncogene 24, 7203 – 7212. | en_US |
dc.identifier.citedreference | Ventura A, Luzi L, Pacini S, Baldari CT, Pelicci PG ( 2002 ) The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter. J. Biol. Chem. 277, 22370 – 22376. | en_US |
dc.identifier.citedreference | Wright WE, Pereira‐Smith OM, Shay JW ( 1989 ) Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts. Mol. Cell. Biol. 9, 3088 – 3092. | en_US |
dc.identifier.citedreference | Yang J, Anzo M, Cohen P ( 2005 ) Control of aging and longevity by IGF‐I signaling. Exp. Gerontol. 40, 867 – 872. | en_US |
dc.identifier.citedreference | Yu F, Yao H, Zhu P, Zhang X, Pan Q, Gong C, Huang Y, Hu X, Su F, Lieberman J, Song E ( 2007 ) let‐7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 131, 1109 – 1123. | en_US |
dc.identifier.citedreference | Zhang W, Ji W, Yang L, Xu Y, Yang J, Zhuang Z ( 2010 ) Epigenetic enhancement of p66Shc during cellular replicative or prematuresenescence. Toxicology 278, 189 – 194. | en_US |
dc.identifier.citedreference | Zhang X, Liu Z, Yi J, Tang H, Xing J, Yu M, Tong T, Shang Y, Gorospe M, Wang W ( 2012 ) NSun2 stabilizes p16INK4 mRNA by methylating the p16 3′UTR. Nat. Commun. 3, 712. | en_US |
dc.identifier.citedreference | Bartel DP ( 2009 ) MicroRNAs: target recognition and regulatory functions. Cell 136, 215 – 233. | en_US |
dc.identifier.citedreference | Bordone L, Guarente L ( 2005 ) Calorie restriction, SIRT1 and metabolism: understanding longevity. Nat. Rev. Mol. Cell Biol. 6, 298 – 305. | en_US |
dc.identifier.citedreference | Chang N, Yi J, Guo G, Liu X, Shang Y, Tong T, Cui Q, Zhan M, Gorospe M, Wang W ( 2010 ) HuR uses AUF1 as a cofactor to promote p16 INK4 mRNA decay. Mol. Cell. Biol. 30, 3875 – 3886. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.