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Advances in the healing of flexor tendon injuries
dc.contributor.authorSammer, Douglas M.en_US
dc.contributor.authorChung, Kevin C.en_US
dc.date.accessioned2014-05-23T15:59:06Z
dc.date.availableWITHHELD_13_MONTHSen_US
dc.date.available2014-05-23T15:59:06Z
dc.date.issued2014-05en_US
dc.identifier.citationSammer, Douglas M.; Chung, Kevin C. (2014). "Advances in the healing of flexor tendon injuries." Wound Repair and Regeneration : 25-29.en_US
dc.identifier.issn1067-1927en_US
dc.identifier.issn1524-475Xen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/106844
dc.description.abstractThe intrasynovial flexor tendons of the hand are critical for normal hand function. Injury to these tendons can result in absent finger flexion, and a subsequent loss of overall hand function. The surgical techniques used to repair these tendons have improved in the past few decades, as have the postoperative rehabilitation protocols. In spite of these advances, intrasynovial flexor tendon repairs continue to be plagued by postoperative scar formation, which limits tendon gliding and prevents a full functional recovery. This paper describes the current challenges of flexor tendon repair, and evaluates the most recent advances and strategies for achieving an excellent functional outcome.en_US
dc.publisherElsevieren_US
dc.publisherWiley Periodicals, Inc.en_US
dc.titleAdvances in the healing of flexor tendon injuriesen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMedicine (General)en_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/106844/1/wrr12161.pdf
dc.identifier.doi10.1111/wrr.12161en_US
dc.identifier.sourceWound Repair and Regenerationen_US
dc.identifier.citedreferenceSpeer DP, Feldman S, Chvapil M. The control of peritendinous adhesions using topical beta‐aminopropionitrile base. J Surg Res 1985; 38: 252 – 257.en_US
dc.identifier.citedreferenceHerzog M, Lindsay WK, McCain WG. Effect of beta‐aminioproprionitrile on adhesions following digital flexor tendon repair in chickens. Surg Forum 1970; 21: 509 – 511.en_US
dc.identifier.citedreferenceSalti NI, Tuel RJ, Mass DP. Effect of hyaluronic acid on rabbit profundus flexor tendon healing in vitro. J Surg Res 1993; 55: 411 – 415.en_US
dc.identifier.citedreferenceThomas SC, Jones LC, Hungerford DS. Hyaluronic acid and its effect on postoperative adhesions in the rabbit flexor tendon. A preliminary look. Clin Orthop Relat Res 1986; 206: 281 – 289.en_US
dc.identifier.citedreferenceKhan U, Occleston NL, Khaw PT, McGrouther DA. Single exposures to 5‐fluorouracil: a possible mode of targeted therapy to reduce contractile scarring in the injured tendon. Plast Reconstr Surg 1997; 99: 465 – 471.en_US
dc.identifier.citedreferenceZhao C, Sun YL, Kirk RL, Thoreson AR, Jay GD, Moran SL, et al. Effects of a lubricin‐containing compound on the results of flexor tendon repair in a canine model in vivo. J Bone Joint Surg Am 2010; 92: 1453 – 1461.en_US
dc.identifier.citedreferenceZhao C, Chieh HF, Bakri K, Ikeda J, Sun YL, Moran SL, et al. The effects of bone marrow stromal cell transplants on tendon healing in vitro. Med Eng Phys 2009; 31: 1271 – 1275.en_US
dc.identifier.citedreferenceMehta V, Kang Q, Luo J, He TC, Haydon RC, Mass DP. Characterization of adenovirus‐mediated gene transfer in rabbit flexor tendons. J Hand Surg [Am] 2005; 30: 136 – 141.en_US
dc.identifier.citedreferenceTang JB, Cao Y, Zhu B, Xin KQ, Wang XT, Liu PY. Adeno‐associated virus‐2‐mediated bFGF gene transfer to digital flexor tendons significantly increases healing strength. an in vivo study. J Bone Joint Surg Am 2008; 90: 1078 – 1089.en_US
dc.identifier.citedreferenceLou J, Tu Y, Burns M, Silva MJ, Manske P. BMP‐12 gene transfer augmentation of lacerated tendon repair. J Orthop Res 2001; 19: 1199 – 1202.en_US
dc.identifier.citedreferenceBolt P, Clerk AN, Luu HH, Kang Q, Kummer JL, Deng ZL, et al. BMP‐14 gene therapy increases tendon tensile strength in a rat model of Achilles tendon injury. J Bone Joint Surg Am 2007; 89: 1315 – 1320.en_US
dc.identifier.citedreferenceThomopoulos S, Harwood FL, Silva MJ, Amiel D, Gelberman RH. Effect of several growth factors on canine flexor tendon fibroblast proliferation and collagen synthesis in vitro. J Hand Surg [Am] 2005; 30: 441 – 447.en_US
dc.identifier.citedreferenceGelberman RH, Thomopoulos S, Sakiyama‐Elbert SE, Das R, Silva MJ. The early effects of sustained platelet‐derived growth factor administration on the functional and structural properties of repaired intrasynovial flexor tendons: an in vivo biomechanic study at 3 weeks in canines. J Hand Surg [Am] 2007; 32: 373 – 379.en_US
dc.identifier.citedreferenceThomopoulos S, Zaegel M, Das R, Harwood FL, Silva MJ, Amiel D, et al. PDGF‐BB released in tendon repair using a novel delivery system promotes cell proliferation and collagen remodeling. J Orthop Res 2007; 25: 1358 – 1368.en_US
dc.identifier.citedreferenceSakiyama‐Elbert SE, Das R, Gelberman RH, Harwood F, Amiel D, Thomopoulos S. Controlled‐release kinetics and biologic activity of platelet‐derived growth factor‐BB for use in flexor tendon repair. J Hand Surg [Am] 2008; 33: 1548 – 1557.en_US
dc.identifier.citedreferenceMorizaki Y, Zhao C, An KN, Amadio PC. The effects of platelet‐rich plasma on bone marrow stromal cell transplants for tendon healing in vitro. J Hand Surg [Am] 2010; 35: 1833 – 1841.en_US
dc.identifier.citedreferenceIkeda J, Zhao C, Moran SL, An KN, Amadio PC. Effects of synovial interposition on healing in a canine tendon explant culture model. J Hand Surg [Am] 2010; 35: 1153 – 1159.en_US
dc.identifier.citedreferenceMason ML, Allen HS. The rate of healing of tendons: an experimental study of tensile strength. Ann Surg 1941; 113: 424 – 459.en_US
dc.identifier.citedreferenceBuckwalter JA. Effects of early motion on healing of musculoskeletal tissues. Hand Clin 1996; 12: 13 – 24.en_US
dc.identifier.citedreferenceFeehan LM, Beauchene JG. Early tensile properties of healing chicken flexor tendons: early controlled passive motion versus postoperative immobilization. J Hand Surg [Am] 1990; 15: 63 – 68.en_US
dc.identifier.citedreferenceWray RC Jr, Ollinger H, Lowrey R, Weeks PM. Effect of continuous load on the mechanical properties of tendon adhesions. Hand 1981; 13: 92 – 96.en_US
dc.identifier.citedreferenceAoki M, Kubota H, Pruitt DL, Manske PR. Biomechanical and histologic characteristics of canine flexor tendon repair using early postoperative mobilization. J Hand Surg [Am] 1997; 22: 107 – 114.en_US
dc.identifier.citedreferenceTanaka H, Manske PR, Pruitt DL, Larson BJ. Effect of cyclic tension on lacerated flexor tendons in vitro. J Hand Surg [Am] 1995; 20: 467 – 473.en_US
dc.identifier.citedreferenceMay EJ, Silfverskiold KL, Sollerman CJ. The correlation between controlled range of motion with dynamic traction and results after flexor tendon repair in zone II. J Hand Surg [Am] 1992; 17: 1133 – 1139.en_US
dc.identifier.citedreferenceSilfverskiold KL, May EJ, Oden A. Factors affecting results after flexor tendon repair in zone II: a multivariate prospective analysis. J Hand Surg [Am] 1993; 18: 654 – 662.en_US
dc.identifier.citedreferenceDovelle S, Heeter PK. The Washington Regimen: rehabilitation of the hand following flexor tendon injuries. Phys Ther 1989; 69: 1034 – 1040.en_US
dc.identifier.citedreferencePettengill KM. The evolution of early mobilization of the repaired flexor tendon. J Hand Ther 2005; 18: 157 – 168.en_US
dc.identifier.citedreferenceDuran R, Houser R. Controlled passive motion following flexor tendon repair in zones 2 and 3. AAOS Symposium on Tendon Surgery in the Hand. St. Louis: The C.V. Mosby Co., 1975.en_US
dc.identifier.citedreferenceMay EJ, Silfverskiold KL, Sollerman CJ. Controlled mobilization after flexor tendon repair in zone II: a prospective comparison of three methods. J Hand Surg [Am] 1992; 17: 942 – 952.en_US
dc.identifier.citedreferenceLister GD, Kleinert HE, Kutz JE, Atasoy E. Primary flexor tendon repair followed by immediate controlled mobilization. J Hand Surg [Am] 1977; 2: 441 – 451.en_US
dc.identifier.citedreferenceCannon N. Post flexor tendon repair motion protocol. Indiana Hand Center Newsl 1993; 1: 13 – 17.en_US
dc.identifier.citedreferenceCullen KW, Tolhurst P, Lang D, Page RE. Flexor tendon repair in zone 2 followed by controlled active mobilisation. J Hand Surg [Br] 1989; 14: 392 – 395.en_US
dc.identifier.citedreferenceElliot D, Moiemen NS, Flemming AF, Harris SB, Foster AJ. The rupture rate of acute flexor tendon repairs mobilized by the controlled active motion regimen. J Hand Surg [Br] 1994; 19: 607 – 612.en_US
dc.identifier.citedreferenceGratton P. Early active mobilization after flexor tendon repairs. J Hand Ther 1993; 6: 285 – 289.en_US
dc.identifier.citedreferenceSmall JO, Brennen MD, Colville J. Early active mobilisation following flexor tendon repair in zone 2. J Hand Surg [Br] 1989; 14: 383 – 391.en_US
dc.identifier.citedreferenceBainbridge LC, Robertson C, Gillies D, Elliot D. A comparison of post‐operative mobilization of flexor tendon repairs with “passive flexion‐active extension” and “controlled active motion” techniques. J Hand Surg [Br] 1994; 19: 517 – 521.en_US
dc.identifier.citedreferenceChesney A, Chauhan A, Kattan A, Farrokhyar F, Thoma A. Systematic review of flexor tendon rehabilitation protocols in zone II of the hand. Plast Reconstr Surg 2011; 127: 1583 – 1592.en_US
dc.identifier.citedreferenceTrumble TE, Vedder NB, Seiler JG 3rd, Hanel DP, Diao E, Pettrone S. Zone‐II flexor tendon repair: a randomized prospective trial of active place‐and‐hold therapy compared with passive motion therapy. J Bone Joint Surg Am 2010; 92: 1381 – 1389.en_US
dc.identifier.citedreferenceJebsen RH, Taylor N, Trieschmann RB, Trotter MJ, Howard LA. An objective and standardized test of hand function. Arch Phys Med Rehabil 1969; 50: 311 – 319.en_US
dc.identifier.citedreferenceWaljee JF, Kim HM, Burns PB, Chung KC. Development of a brief, 12‐item version of the Michigan Hand Questionnaire. Plast Reconstr Surg 2011; 128: 208 – 220.en_US
dc.identifier.citedreferenceWaljee JF, Chung KC, Kim HM, Burns PB, Burke FD, Wilgis EF, Fox DA. Validity and responsiveness of the Michigan Hand Questionnaire in patients with rheumatoid arthritis: a multicenter, international study. Arthritis Care Res (Hoboken) 2010; 62: 1569 – 1577.en_US
dc.identifier.citedreferenceShauver MJ, Chung KC. The minimal clinically important difference of the Michigan hand outcomes questionnaire. J Hand Surg [Am] 2009; 34: 509 – 514.en_US
dc.identifier.citedreferenceKotsis SV, Lau FH, Chung KC. Responsiveness of the Michigan Hand Outcomes Questionnaire and physical measurements in outcome studies of distal radius fracture treatment. J Hand Surg [Am] 2007; 32: 84 – 90.en_US
dc.identifier.citedreferenceKotsis SV, Chung KC. Responsiveness of the Michigan Hand Outcomes Questionnaire and the Disabilities of the Arm, Shoulder and Hand questionnaire in carpal tunnel surgery. J Hand Surg [Am] 2005; 30: 81 – 86.en_US
dc.identifier.citedreferenceChung KC, Hamill JB, Walters MR, Hayward RA. The Michigan Hand Outcomes Questionnaire (MHQ): assessment of responsiveness to clinical change. Ann Plast Surg 1999; 42: 619 – 622.en_US
dc.identifier.citedreferenceChung KC, Pillsbury MS, Walters MR, Hayward RA. Reliability and validity testing of the Michigan Hand Outcomes Questionnaire. J Hand Surg [Am] 1998; 23: 575 – 587.en_US
dc.identifier.citedreferenceIkuta Y, Tsuge K. Postoperative results of looped nylon suture used in injuries of the digital flexor tendons. J Hand Surg [Br] 1985; 10: 67 – 72.en_US
dc.identifier.citedreferenceKessler I. The “grasping” technique for tendon repair. Hand 1973; 5: 253 – 255.en_US
dc.identifier.citedreferenceKessler I, Nissim F. Primary repair without immobilization of flexor tendon division within the digital sheath. An experimental and clinical study. Acta Orthop Scand 1969; 40: 587 – 601.en_US
dc.identifier.citedreferenceMashadi ZB, Amis AA. The effect of locking loops on the strength of tendon repair. J Hand Surg [Br] 1991; 16: 35 – 39.en_US
dc.identifier.citedreferenceSavage R, Risitano G. Flexor tendon repair using a “six strand” method of repair and early active mobilisation. J Hand Surg [Br] 1989; 14: 396 – 399.en_US
dc.identifier.citedreferenceTsuge K, Ikuta Y, Matsuishi Y. Intra‐tendinous tendon suture in the hand—a new technique. Hand 1975; 7: 250 – 255.en_US
dc.identifier.citedreferenceWade PJ, Wetherell RG, Amis AA. Flexor tendon repair: significant gain in strength from the Halsted peripheral suture technique. J Hand Surg [Br] 1989; 14: 232 – 235.en_US
dc.identifier.citedreferenceMcLarney E, Hoffman H, Wolfe SW. Biomechanical analysis of the cruciate four‐strand flexor tendon repair. J Hand Surg [Am] 1999; 24: 295 – 301.en_US
dc.identifier.citedreferenceBecker H, Davidoff M. Eliminating the gap in flexor tendon surgery. A new method of suture. Hand 1977; 9: 306 – 311.en_US
dc.identifier.citedreferenceStrickland JW. Flexor tendon injuries. Part 2. Flexor tendon repair. Orthop Rev 1986; 15: 701 – 721.en_US
dc.identifier.citedreferenceSeiler JG 3rd. Flexor tendon injury. In: Wolfe SW, Hotchkiss RN, Pederson WC, Kozin SH, editors. Green's operative hand surgery, vol. 1, 6th ed. Philadelphia: Elsevier, 2011: 189 – 207.en_US
dc.identifier.citedreferenceAnsari U, Lawson RD, Peterson JL, Appleyard RC, Tonkin MA. Effect of partial versus complete circumferential repair on flexor tendon strength in cadavers. J Hand Surg [Am] 2009; 34: 1771 – 1776.en_US
dc.identifier.citedreferenceZeplin PH, Zahn RK, Meffert RH, Schmidt K. Biomechanical evaluation of flexor tendon repair using barbed suture material: a comparative ex vivo study. J Hand Surg [Am] 2011; 36: 446 – 449.en_US
dc.identifier.citedreferenceParikh PM, Davison SP, Higgins JP. Barbed suture tenorrhaphy: an ex vivo biomechanical analysis. Plast Reconstr Surg 2009; 124: 1551 – 1558.en_US
dc.identifier.citedreferenceMarrero‐Amadeo IC, Chauhan A, Warden SJ, Merrell GA. Flexor tendon repair with a knotless barbed suture: a comparative biomechanical study. J Hand Surg [Am] 2011; 36: 1204 – 1208.en_US
dc.identifier.citedreferenceHanff G, Hagberg L. Prevention of restrictive adhesions with expanded polytetrafluoroethylene diffusible membrane following flexor tendon repair: an experimental study in rabbits. J Hand Surg [Am] 1998; 23: 658 – 664.en_US
dc.identifier.citedreferenceSiddiqi NA, Hamada Y, Ide T, Akamatsu N. Effects of hydroxyapatite and alumina sheaths on postoperative peritendinous adhesions in chickens. J Appl Biomater 1995; 6: 43 – 53.en_US
dc.identifier.citedreferenceKarakurum G, Buyukbebeci O, Kalender M, Gulec A. Seprafilm interposition for preventing adhesion formation after tenolysis. An experimental study on the chicken flexor tendons. J Surg Res 2003; 113: 195 – 200.en_US
dc.identifier.citedreferenceSzadok K. Liquid silicones in reconstructive surgery of the tendons. Experimental studies. Polim Med 1979; 9: 187 – 207.en_US
dc.identifier.citedreferenceAustin RT, Walker F. Flexor tendon healing and adhesion formation after Sterispon wrapping: a study in the rabbit. Injury 1979; 10: 211 – 216.en_US
dc.identifier.citedreferenceEskeland G, Eskeland T, Hovig T, Teigland J. The ultrastructure of normal digital flexor tendon sheath and of the tissue formed around silicone and polyethylene implants in man. J Bone Joint Surg Br 1977; 59: 206 – 212.en_US
dc.identifier.citedreferenceGudemez E, Eksioglu F, Korkusuz P, Asan E, Gursel I, Hasirci V. Chondroitin sulfate‐coated polyhydroxyethyl methacrylate membrane prevents adhesion in full‐thickness tendon tears of rabbits. J Hand Surg [Am] 2002; 27: 293 – 306.en_US
dc.identifier.citedreferenceHagberg L, Gerdin B. Sodium hyaluronate as an adjunct in adhesion prevention after flexor tendon surgery in rabbits. J Hand Surg [Am] 1992; 17: 935 – 941.en_US
dc.identifier.citedreferenceMoran SL, Ryan CK, Orlando GS, Pratt CE, Michalko KB. Effects of 5‐fluorouracil on flexor tendon repair. J Hand Surg [Am] 2000; 25: 242 – 251.en_US
dc.identifier.citedreferenceNamba J, Shimada K, Saito M, Murase T, Yamada H, Yoshikawa H. Modulation of peritendinous adhesion formation by alginate solution in a rabbit flexor tendon model. J Biomed Mater Res B Appl Biomater 2007; 80: 273 – 279.en_US
dc.identifier.citedreferenceKapetanos G. The effect of the local corticosteroids on the healing and biomechanical properties of the partially injured tendon. Clin Orthop Relat Res 1982; 163: 170 – 179.en_US
dc.identifier.citedreferenceAlbrechtsen SJ, Harvey JS Jr. Dimethyl sulfoxide. Biomechanical effects on tendons. Am J Sports Med 1982; 10: 177 – 179.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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